hmeg3_RS21425 bb6ec3cb186444e4ea93c3cca2681057 327 Pfam PF09084 NMT1/THI5 like 40 243 4.2E-29 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS21425 bb6ec3cb186444e4ea93c3cca2681057 327 SUPERFAMILY SSF53850 27 253 5.89E-25 T 28-03-2018 hmeg3_RS21425 bb6ec3cb186444e4ea93c3cca2681057 327 Gene3D G3DSA:3.40.190.10 26 137 1.6E-16 T 28-03-2018 hmeg3_RS21425 bb6ec3cb186444e4ea93c3cca2681057 327 Gene3D G3DSA:3.40.190.10 138 325 3.2E-21 T 28-03-2018 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 149 160 3.0E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 3.0E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 282 305 3.0E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 59 78 3.0E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 Gene3D G3DSA:3.40.50.1370 4 175 1.2E-56 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 169 314 1.0E-24 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 SUPERFAMILY SSF53671 12 318 7.73E-92 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 59 66 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 12 319 40.459 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 13 161 2.2E-36 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 13 316 9.2E-89 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 Gene3D G3DSA:3.40.50.1370 176 318 1.9E-45 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 233 242 5.5E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 148 165 5.5E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 298 312 5.5E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 274 279 5.5E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 49 71 5.5E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS21380 be7c35ada16c968d539aa93e1a6c8506 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 87 96 5.5E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00267 395 567 2.4E-60 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00052 577 823 5.0E-98 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Gene3D G3DSA:3.30.450.20 281 403 8.1E-21 T 28-03-2018 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Pfam PF00989 PAS fold 159 270 2.5E-21 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Pfam PF00989 PAS fold 38 148 5.4E-18 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 159 278 1.1E-27 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 287 402 1.1E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 35 157 2.2E-27 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SUPERFAMILY SSF55785 289 392 2.93E-21 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Gene3D G3DSA:3.20.20.450 571 837 7.5E-91 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SUPERFAMILY SSF141868 583 835 1.07E-84 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Pfam PF00990 Diguanylate cyclase, GGDEF domain 407 563 1.5E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Pfam PF13426 PAS domain 292 393 3.4E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SUPERFAMILY SSF55785 28 149 2.97E-25 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SUPERFAMILY SSF55785 151 271 8.08E-27 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Gene3D G3DSA:3.30.70.270 404 570 9.7E-57 T 28-03-2018 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Pfam PF00563 EAL domain 583 818 1.3E-69 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00091 37 103 4.3E-9 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00091 281 347 0.0017 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00091 159 225 9.4E-12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00086 109 151 0.0035 T 28-03-2018 IPR001610 PAC motif hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00086 231 273 9.0E-4 T 28-03-2018 IPR001610 PAC motif hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SMART SM00086 353 395 7.2E-4 T 28-03-2018 IPR001610 PAC motif hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Gene3D G3DSA:3.30.450.20 26 156 1.8E-28 T 28-03-2018 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 Gene3D G3DSA:3.30.450.20 157 280 5.8E-29 T 28-03-2018 hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 402 566 2.9E-43 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11440 3545a35521907c3784a69eca68bb9a79 841 SUPERFAMILY SSF55073 411 568 1.18E-49 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS20450 8549ade484eed795c43ef58373a090fe 272 SUPERFAMILY SSF56300 2 252 4.68E-58 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS20450 8549ade484eed795c43ef58373a090fe 272 Pfam PF00149 Calcineurin-like phosphoesterase 4 198 3.1E-19 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS20450 8549ade484eed795c43ef58373a090fe 272 Gene3D G3DSA:3.60.21.10 1 255 2.3E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS20450 8549ade484eed795c43ef58373a090fe 272 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 255 37.668 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 hmeg3_RS12695 680f94de3231f50152ed88af45713412 449 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 436 3.3E-92 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit hmeg3_RS12695 680f94de3231f50152ed88af45713412 449 PIRSF PIRSF006066 6 448 6.9E-92 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS12695 680f94de3231f50152ed88af45713412 449 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 442 1.4E-101 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 SUPERFAMILY SSF56719 407 656 4.97E-76 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 589 652 6.9E-25 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Pfam PF01751 Toprim domain 432 541 1.4E-11 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 180 1.5E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 433 447 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 285 298 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 540 552 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 118 132 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 520 537 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 72 85 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 37 52 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 502 518 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR00418 DNA topoisomerase II family signature 592 608 9.5E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 8 660 44.02 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 SMART SM00387 34 183 8.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Gene3D G3DSA:3.30.230.10 227 410 1.8E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Gene3D G3DSA:3.30.565.10 23 226 7.5E-57 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 SMART SM00433 39 656 3.2E-196 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 SUPERFAMILY SSF55874 11 225 4.45E-57 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 144 158 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 32 45 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 184 201 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 381 406 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 467 488 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 357 380 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 313 329 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 PRINTS PR01098 Topoisomerase IV subunit B signature 330 345 1.1E-34 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Gene3D G3DSA:3.40.50.670 414 660 5.6E-80 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 Pfam PF00204 DNA gyrase B 250 404 2.4E-33 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16425 f946a1fb9f5e69e1cefe0e7e05f7e61e 662 SUPERFAMILY SSF54211 228 406 1.4E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS19195 a1bc27d341a9140b9e04622bc9198e35 254 SUPERFAMILY SSF52540 19 251 4.08E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19195 a1bc27d341a9140b9e04622bc9198e35 254 SMART SM00382 45 233 8.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19195 a1bc27d341a9140b9e04622bc9198e35 254 Gene3D G3DSA:3.40.50.300 17 252 3.0E-52 T 28-03-2018 hmeg3_RS19195 a1bc27d341a9140b9e04622bc9198e35 254 Pfam PF00005 ABC transporter 36 181 4.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19195 a1bc27d341a9140b9e04622bc9198e35 254 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 SMART SM00382 156 299 1.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 SUPERFAMILY SSF52172 2 181 7.54E-41 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Gene3D G3DSA:3.40.50.300 134 308 4.7E-31 T 28-03-2018 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Gene3D G3DSA:3.40.50.2300 2 133 6.5E-32 T 28-03-2018 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Pfam PF02954 Bacterial regulatory protein, Fis family 451 490 2.2E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 SMART SM00448 2 113 4.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 SUPERFAMILY SSF52540 135 379 2.9E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 456 473 4.2E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 473 493 4.2E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Pfam PF00158 Sigma-54 interaction domain 136 302 1.2E-69 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Gene3D G3DSA:1.10.10.60 380 496 1.8E-14 T 28-03-2018 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 490 9.7E-205 T 28-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 SUPERFAMILY SSF46689 423 492 7.17E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Pfam PF00072 Response regulator receiver domain 4 113 2.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15455 f7fdb8c74c085729b3c9b6f2b97349be 498 Gene3D G3DSA:1.10.8.60 309 379 5.3E-22 T 28-03-2018 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SMART SM00260 557 697 2.2E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 317 380 3.2E-17 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SUPERFAMILY SSF50341 564 697 7.32E-32 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SMART SM01231 317 380 8.8E-21 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Gene3D G3DSA:1.10.287.560 317 381 2.5E-20 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Gene3D G3DSA:2.40.50.180 580 650 4.5E-11 T 28-03-2018 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Gene3D G3DSA:1.20.120.160 1 144 3.1E-34 T 28-03-2018 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Pfam PF01627 Hpt domain 8 94 6.7E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SUPERFAMILY SSF47384 318 381 2.94E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Pfam PF09078 CheY binding 150 212 2.9E-16 T 28-03-2018 IPR015162 CheY binding hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Gene3D G3DSA:2.30.30.40 651 697 5.7E-21 T 28-03-2018 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SUPERFAMILY SSF47226 4 128 6.54E-33 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SUPERFAMILY SSF55874 383 563 1.83E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Pfam PF01584 CheW-like domain 570 699 1.9E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SMART SM00387 425 565 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 428 564 3.0E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Gene3D G3DSA:3.30.70.400 148 213 9.2E-19 T 28-03-2018 IPR015162 CheY binding hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 2.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 519 2.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 562 2.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 484 2.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 Gene3D G3DSA:3.30.565.10 383 569 2.0E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SMART SM00073 5 102 1.1E-31 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS08705 bbc2f3e3358d60070795dfd6d61c084b 710 SUPERFAMILY SSF55052 149 213 1.12E-12 T 28-03-2018 IPR015162 CheY binding hmeg3_RS12155 27982b613ee4b1dd434d8be228458333 217 SUPERFAMILY SSF161098 13 203 3.53E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12155 27982b613ee4b1dd434d8be228458333 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 107 5.4E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS12155 27982b613ee4b1dd434d8be228458333 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 201 2.4E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12155 27982b613ee4b1dd434d8be228458333 217 Gene3D G3DSA:1.10.3720.10 2 217 1.6E-33 T 28-03-2018 hmeg3_RS05240 4795f6829f3576f6543ea907264efcfb 349 Gene3D G3DSA:1.10.3470.10 4 319 3.2E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS05240 4795f6829f3576f6543ea907264efcfb 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 313 3.0E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02215 103deb117fb1e7205bfef9f65e016835 193 SUPERFAMILY SSF50182 112 185 2.58E-11 T 28-03-2018 IPR010920 LSM domain hmeg3_RS02215 103deb117fb1e7205bfef9f65e016835 193 Pfam PF00924 Mechanosensitive ion channel 67 183 6.4E-14 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 hmeg3_RS02215 103deb117fb1e7205bfef9f65e016835 193 Gene3D G3DSA:2.30.30.60 127 185 1.0E-15 T 28-03-2018 hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 Gene3D G3DSA:3.40.50.300 2 318 1.1E-82 T 28-03-2018 hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 SUPERFAMILY SSF52540 5 251 1.97E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 SMART SM00382 37 229 2.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 296 5.2E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 Pfam PF00005 ABC transporter 29 179 1.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24440 80092b20a69e805fd952f7d56829c355 318 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 316 3.1E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 SUPERFAMILY SSF52540 276 491 1.01E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 Gene3D G3DSA:3.40.50.300 15 244 2.5E-49 T 28-03-2018 hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 SUPERFAMILY SSF52540 20 240 5.02E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 SMART SM00382 291 487 4.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 SMART SM00382 42 231 5.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 Gene3D G3DSA:3.40.50.300 269 504 1.1E-35 T 28-03-2018 hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 ProSitePatterns PS00211 ABC transporters family signature. 411 425 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 Pfam PF00005 ABC transporter 285 438 5.5E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07030 afc34b3ddac497fdbc9271213cc32fa4 525 Pfam PF00005 ABC transporter 33 183 2.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS22600 de37a95ed1cdd9b5f72921037fd95875 150 Pfam PF06347 Bacterial SH3 domain 103 149 3.4E-5 T 28-03-2018 IPR010466 Protein of unknown function DUF1058 hmeg3_RS22600 de37a95ed1cdd9b5f72921037fd95875 150 Pfam PF06347 Bacterial SH3 domain 33 83 6.6E-11 T 28-03-2018 IPR010466 Protein of unknown function DUF1058 hmeg3_RS22600 de37a95ed1cdd9b5f72921037fd95875 150 Gene3D G3DSA:2.40.50.110 16 82 5.4E-5 T 28-03-2018 hmeg3_RS22600 de37a95ed1cdd9b5f72921037fd95875 150 Gene3D G3DSA:2.40.50.110 83 147 0.021 T 28-03-2018 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 SUPERFAMILY SSF53850 104 318 8.87E-21 T 28-03-2018 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 Gene3D G3DSA:3.40.190.10 106 199 3.2E-9 T 28-03-2018 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 Gene3D G3DSA:3.40.190.10 200 289 1.6E-9 T 28-03-2018 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 Pfam PF03466 LysR substrate binding domain 104 315 1.9E-20 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 Gene3D G3DSA:1.10.10.10 17 105 2.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 77 1.2E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 SUPERFAMILY SSF46785 15 126 1.65E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 66 4.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 4.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06380 811d4f8202397a15c2636eac8d56aebf 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 55 4.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19680 aa724b67d4697d3740f45c1b7c589bac 164 SUPERFAMILY SSF55826 8 160 3.27E-38 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS19680 aa724b67d4697d3740f45c1b7c589bac 164 Gene3D G3DSA:3.90.960.10 1 162 5.0E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS19680 aa724b67d4697d3740f45c1b7c589bac 164 Pfam PF04073 Aminoacyl-tRNA editing domain 40 148 9.8E-24 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS19680 aa724b67d4697d3740f45c1b7c589bac 164 PIRSF PIRSF006181 6 163 6.6E-44 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC hmeg3_RS19680 aa724b67d4697d3740f45c1b7c589bac 164 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 11 154 4.8E-46 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 7.7E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 7.7E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 7.7E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 93 189 1.8E-10 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 9 183 1.9E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 184 4.2E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 SUPERFAMILY SSF56784 5 220 3.47E-39 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 7 200 5.5E-52 T 28-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 hmeg3_RS03760 b71f6b88980427e54d3538cdcc0185b2 222 Gene3D G3DSA:3.40.50.1000 2 210 8.4E-19 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SMART SM00388 437 507 1.3E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SUPERFAMILY SSF55785 285 413 1.26E-23 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SMART SM00091 300 367 5.8E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Pfam PF00512 His Kinase A (phospho-acceptor) domain 437 504 1.3E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 549 666 3.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SMART SM00086 373 415 3.3E-6 T 28-03-2018 IPR001610 PAC motif hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SMART SM00387 549 668 5.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SUPERFAMILY SSF47384 427 504 9.22E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Gene3D G3DSA:3.30.450.20 42 199 1.9E-6 T 28-03-2018 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Pfam PF00989 PAS fold 302 412 1.4E-14 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 SUPERFAMILY SSF55874 510 665 6.29E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Gene3D G3DSA:3.30.565.10 505 668 2.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 613 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 665 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 627 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 646 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Gene3D G3DSA:1.10.287.130 429 503 4.4E-9 T 28-03-2018 hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 298 419 6.3E-26 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19715 fdc736d10dd0fa9e7385449802827b83 671 Gene3D G3DSA:3.30.450.20 276 428 6.1E-27 T 28-03-2018 hmeg3_RS11030 9ee38c57812258d255784c6d37c63bac 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 298 4.9E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11030 9ee38c57812258d255784c6d37c63bac 304 Gene3D G3DSA:1.10.3720.10 28 292 1.5E-37 T 28-03-2018 hmeg3_RS11030 9ee38c57812258d255784c6d37c63bac 304 SUPERFAMILY SSF161098 34 304 5.42E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23410 5fe46e1bf37732f865b8f91cd5b730b6 308 Gene3D G3DSA:3.40.50.720 13 118 1.9E-12 T 28-03-2018 hmeg3_RS23410 5fe46e1bf37732f865b8f91cd5b730b6 308 Gene3D G3DSA:3.40.50.720 119 274 1.1E-36 T 28-03-2018 hmeg3_RS23410 5fe46e1bf37732f865b8f91cd5b730b6 308 SUPERFAMILY SSF52283 37 91 1.06E-6 T 28-03-2018 hmeg3_RS23410 5fe46e1bf37732f865b8f91cd5b730b6 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 273 1.5E-43 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS23410 5fe46e1bf37732f865b8f91cd5b730b6 308 SUPERFAMILY SSF51735 94 274 3.88E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 Pfam PF00072 Response regulator receiver domain 5 116 4.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 Gene3D G3DSA:3.40.50.2300 1 122 5.4E-36 T 28-03-2018 hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 SUPERFAMILY SSF46894 134 229 8.5E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 SMART SM00862 152 228 1.3E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 SUPERFAMILY SSF52172 2 125 1.12E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 Gene3D G3DSA:1.10.10.10 123 235 1.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 SMART SM00448 3 115 1.3E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11050 f4f6c2ce18112852e64b42a6fe0c2fb8 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 7.9E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 Pfam PF00672 HAMP domain 357 402 1.7E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 Gene3D G3DSA:1.10.287.950 460 659 8.3E-50 T 28-03-2018 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 SMART SM00304 355 407 1.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 Gene3D G3DSA:1.10.287.950 328 459 7.4E-12 T 28-03-2018 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 Gene3D G3DSA:3.30.450.20 46 327 2.0E-30 T 28-03-2018 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 467 622 2.1E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 SUPERFAMILY SSF103190 107 214 7.46E-15 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 SMART SM00283 408 655 2.0E-94 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 SUPERFAMILY SSF58104 375 656 9.68E-76 T 28-03-2018 hmeg3_RS19770 7dd271da94c0735e04c1c39a0a70da58 713 Pfam PF17201 Cache 3/Cache 2 fusion domain 45 332 2.6E-93 T 28-03-2018 IPR033462 Cache 3/Cache 2 fusion domain hmeg3_RS10095 99067cc11c4a0e4141313dea8717e5bb 407 SUPERFAMILY SSF103473 16 392 1.83E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10095 99067cc11c4a0e4141313dea8717e5bb 407 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 30 392 1.4E-67 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB hmeg3_RS10095 99067cc11c4a0e4141313dea8717e5bb 407 Gene3D G3DSA:1.20.1250.20 13 207 7.4E-20 T 28-03-2018 hmeg3_RS10095 99067cc11c4a0e4141313dea8717e5bb 407 Gene3D G3DSA:1.20.1250.20 220 393 1.5E-14 T 28-03-2018 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 Gene3D G3DSA:3.30.70.360 200 311 5.3E-22 T 28-03-2018 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 Pfam PF07687 Peptidase dimerisation domain 193 302 6.1E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 29 399 5.3E-107 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 Gene3D G3DSA:3.40.630.10 17 199 4.5E-31 T 28-03-2018 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 SUPERFAMILY SSF53187 322 404 9.57E-56 T 28-03-2018 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 SUPERFAMILY SSF53187 25 196 9.57E-56 T 28-03-2018 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 Pfam PF01546 Peptidase family M20/M25/M40 89 400 5.4E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS01860 901cf9a6881defa097b9fef4cbd930c4 408 SUPERFAMILY SSF55031 197 301 5.83E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Pfam PF13193 AMP-binding enzyme C-terminal domain 513 596 6.4E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 1 631 0.0 T 28-03-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Gene3D G3DSA:2.30.38.10 406 497 6.4E-10 T 28-03-2018 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 SUPERFAMILY SSF56801 4 623 5.63E-154 T 28-03-2018 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Gene3D G3DSA:3.40.50.980 49 241 1.6E-41 T 28-03-2018 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Gene3D G3DSA:3.40.50.980 242 405 1.2E-33 T 28-03-2018 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 5 57 7.8E-21 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Pfam PF00501 AMP-binding enzyme 62 504 1.7E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS15415 91d7a2a797a4a2265a3ef53cdf3ee5c3 632 Gene3D G3DSA:3.30.300.30 498 611 4.1E-23 T 28-03-2018 hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 Pfam PF00990 Diguanylate cyclase, GGDEF domain 212 364 6.3E-42 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 SUPERFAMILY SSF55073 216 363 8.63E-44 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 Pfam PF01590 GAF domain 89 200 7.6E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 Gene3D G3DSA:3.30.450.40 36 208 5.0E-15 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 SMART SM00267 200 368 2.3E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 SMART SM00065 41 208 0.0062 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 Gene3D G3DSA:3.30.70.270 209 365 7.2E-49 T 28-03-2018 hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 207 365 1.3E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS24380 d1918e2d33ea5e26af379de3c421405b 369 SUPERFAMILY SSF55781 44 210 4.66E-16 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS10890 d0bccdbabae05c168b579f2b7351f313 292 Pfam PF05726 Pirin C-terminal cupin domain 176 272 3.7E-23 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 hmeg3_RS10890 d0bccdbabae05c168b579f2b7351f313 292 PIRSF PIRSF006232 1 282 3.8E-83 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 hmeg3_RS10890 d0bccdbabae05c168b579f2b7351f313 292 Gene3D G3DSA:2.60.120.10 12 247 2.1E-65 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS10890 d0bccdbabae05c168b579f2b7351f313 292 SUPERFAMILY SSF51182 15 282 4.11E-74 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS10890 d0bccdbabae05c168b579f2b7351f313 292 Pfam PF02678 Pirin 18 123 3.0E-33 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 SMART SM00490 262 343 1.1E-27 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 Gene3D G3DSA:3.40.50.300 227 463 9.6E-41 T 28-03-2018 hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 Pfam PF00271 Helicase conserved C-terminal domain 243 342 4.7E-25 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 Gene3D G3DSA:3.40.50.300 19 226 6.7E-58 T 28-03-2018 hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 SUPERFAMILY SSF52540 80 364 3.52E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 Pfam PF00270 DEAD/DEAH box helicase 34 200 6.6E-47 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 SMART SM00487 29 226 4.5E-62 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS10400 decc8f07c2cdca009ada6a908e280835 468 Pfam PF03880 DbpA RNA binding domain 393 463 1.9E-21 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Pfam PF00563 EAL domain 448 683 1.5E-77 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SMART SM00267 258 432 8.3E-28 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SUPERFAMILY SSF55785 131 256 3.54E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SMART SM00448 6 118 2.9E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 267 423 3.4E-15 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SMART SM00091 143 210 4.1E-7 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SUPERFAMILY SSF141868 448 695 1.1E-93 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Gene3D G3DSA:3.20.20.450 436 699 6.1E-106 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SUPERFAMILY SSF55073 274 433 5.02E-24 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SUPERFAMILY SSF52172 5 135 6.26E-24 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Gene3D G3DSA:3.30.70.270 267 435 1.7E-32 T 28-03-2018 hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 264 2.6E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Gene3D G3DSA:3.30.450.20 138 266 3.3E-24 T 28-03-2018 hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Pfam PF08448 PAS fold 157 258 2.6E-9 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Pfam PF00072 Response regulator receiver domain 8 118 6.8E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 SMART SM00052 442 688 1.8E-119 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Gene3D G3DSA:3.40.50.2300 1 137 3.7E-24 T 28-03-2018 hmeg3_RS12645 7814c9d56ab0aca7e7ff3e1be623b713 700 Pfam PF00990 Diguanylate cyclase, GGDEF domain 270 422 4.6E-23 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Gene3D G3DSA:3.30.450.20 198 312 5.7E-5 T 28-03-2018 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Gene3D G3DSA:3.40.50.2300 611 729 6.9E-25 T 28-03-2018 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 591 1.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Pfam PF00072 Response regulator receiver domain 617 721 3.0E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 SMART SM00448 615 728 7.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Gene3D G3DSA:1.10.287.130 363 422 8.2E-4 T 28-03-2018 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Pfam PF02743 Cache domain 118 300 1.8E-13 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 SMART SM00387 476 593 1.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 SUPERFAMILY SSF55874 433 591 1.31E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Gene3D G3DSA:3.30.565.10 423 606 5.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 550 1.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 536 1.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 1.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 1.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 SUPERFAMILY SSF52172 613 726 2.99E-25 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06430 51b2bafa90db00ab1923457797834e62 729 Gene3D G3DSA:3.30.450.20 89 197 3.3E-12 T 28-03-2018 hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 Pfam PF00005 ABC transporter 25 173 5.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 SMART SM00382 34 228 2.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 Gene3D G3DSA:3.40.50.300 1 240 3.8E-63 T 28-03-2018 hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 Pfam PF12704 MacB-like periplasmic core domain 276 494 9.0E-39 T 28-03-2018 IPR025857 MacB-like periplasmic core domain hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 Pfam PF02687 FtsX-like permease family 557 645 1.7E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 hmeg3_RS08250 3c26e0c3bacbd7f493d243ca3dac430f 652 SUPERFAMILY SSF52540 5 227 1.04E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10950 71bf33b7bffb29d2e6ec2eea886060c8 340 SUPERFAMILY SSF53850 33 272 1.09E-26 T 28-03-2018 hmeg3_RS10950 71bf33b7bffb29d2e6ec2eea886060c8 340 Gene3D G3DSA:3.40.190.10 28 139 3.9E-7 T 28-03-2018 hmeg3_RS10950 71bf33b7bffb29d2e6ec2eea886060c8 340 Pfam PF13379 NMT1-like family 28 273 1.0E-17 T 28-03-2018 hmeg3_RS10950 71bf33b7bffb29d2e6ec2eea886060c8 340 Gene3D G3DSA:3.40.190.10 140 338 8.9E-20 T 28-03-2018 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SUPERFAMILY SSF52540 6 288 1.95E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SUPERFAMILY SSF54980 409 486 1.65E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SUPERFAMILY SSF54980 609 698 2.19E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SMART SM00889 485 604 1.2E-76 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Pfam PF00679 Elongation factor G C-terminus 606 693 5.3E-32 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Gene3D G3DSA:2.40.30.10 289 404 1.2E-28 T 28-03-2018 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SUPERFAMILY SSF50447 271 407 1.63E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Gene3D G3DSA:3.30.70.870 405 498 1.1E-37 T 28-03-2018 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.0E-64 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SMART SM00838 606 695 1.4E-54 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 111.721 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Gene3D G3DSA:3.40.50.300 1 288 2.4E-58 T 28-03-2018 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 SUPERFAMILY SSF54211 484 605 2.17E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Gene3D G3DSA:3.30.230.10 499 614 5.7E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Pfam PF03764 Elongation factor G, domain IV 484 604 4.5E-49 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Gene3D G3DSA:3.30.70.240 615 694 1.1E-32 T 28-03-2018 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Pfam PF03144 Elongation factor Tu domain 2 329 396 5.0E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.3E-30 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS22875 5650c6eaac7584e6520c1e818db7be85 701 Pfam PF14492 Elongation Factor G, domain II 409 483 1.3E-34 T 28-03-2018 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 Pfam PF03466 LysR substrate binding domain 91 294 1.2E-34 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 SUPERFAMILY SSF46785 4 114 7.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 Gene3D G3DSA:3.40.190.10 181 270 2.6E-15 T 28-03-2018 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 Gene3D G3DSA:1.10.10.10 1 87 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 Gene3D G3DSA:3.40.190.10 92 180 3.3E-18 T 28-03-2018 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 SUPERFAMILY SSF53850 91 280 1.07E-33 T 28-03-2018 hmeg3_RS13370 28045cca0584646682824a408b646ff9 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.1E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 SMART SM00283 267 514 4.4E-68 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 SMART SM00304 214 266 5.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 Pfam PF00672 HAMP domain 214 262 7.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 189 209 1.5E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 SUPERFAMILY SSF47170 40 173 4.45E-6 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 Pfam PF02203 Tar ligand binding domain homologue 1 152 4.0E-12 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 SUPERFAMILY SSF58104 234 520 1.57E-64 T 28-03-2018 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 481 2.8E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 Gene3D G3DSA:1.10.287.950 29 322 5.7E-18 T 28-03-2018 hmeg3_RS13130 c3b7dc1d1f64ef6b7f01833aa8387d0c 554 Gene3D G3DSA:1.10.287.950 323 518 3.8E-42 T 28-03-2018 hmeg3_RS02310 0c722bc5939b4479dbc3ba2a3f26254d 265 SMART SM00382 43 245 2.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02310 0c722bc5939b4479dbc3ba2a3f26254d 265 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 19 265 2.7E-116 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 hmeg3_RS02310 0c722bc5939b4479dbc3ba2a3f26254d 265 SUPERFAMILY SSF52540 18 254 3.4E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02310 0c722bc5939b4479dbc3ba2a3f26254d 265 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS02310 0c722bc5939b4479dbc3ba2a3f26254d 265 Pfam PF00005 ABC transporter 34 190 7.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS02310 0c722bc5939b4479dbc3ba2a3f26254d 265 Gene3D G3DSA:3.40.50.300 15 263 6.1E-68 T 28-03-2018 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 PRINTS PR00147 DNA photolyase signature 358 376 1.7E-27 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 PRINTS PR00147 DNA photolyase signature 338 354 1.7E-27 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 PRINTS PR00147 DNA photolyase signature 397 411 1.7E-27 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 PRINTS PR00147 DNA photolyase signature 147 163 1.7E-27 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 SUPERFAMILY SSF52425 7 181 5.1E-49 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 Gene3D G3DSA:1.10.579.10 306 491 3.8E-77 T 28-03-2018 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 SUPERFAMILY SSF48173 211 491 3.92E-108 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 Gene3D G3DSA:3.40.50.620 3 134 1.5E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 Gene3D G3DSA:1.25.40.80 136 305 2.0E-37 T 28-03-2018 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 Pfam PF03441 FAD binding domain of DNA photolyase 286 487 5.1E-87 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 Pfam PF00875 DNA photolyase 7 167 1.5E-47 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 hmeg3_RS16965 a1e92edd8c5a845278d3ee320988e92f 498 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 358 377 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 SUPERFAMILY SSF54782 223 311 5.49E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 230 297 9.8E-16 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 234 250 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 SUPERFAMILY SSF53850 8 222 4.88E-80 T 28-03-2018 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 PRINTS PR00151 Porphobilinogen deaminase signature 79 98 1.2E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 PRINTS PR00151 Porphobilinogen deaminase signature 146 163 1.2E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 PRINTS PR00151 Porphobilinogen deaminase signature 233 250 1.2E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 PRINTS PR00151 Porphobilinogen deaminase signature 127 144 1.2E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 PRINTS PR00151 Porphobilinogen deaminase signature 48 68 1.2E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 8 300 37.003 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 9 300 8.7E-106 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 Gene3D G3DSA:3.40.190.10 110 202 6.2E-36 T 28-03-2018 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 PIRSF PIRSF001438 2 315 5.7E-113 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 Gene3D G3DSA:3.30.160.40 224 307 4.2E-21 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 Gene3D G3DSA:3.40.190.10 2 109 8.5E-45 T 28-03-2018 hmeg3_RS16905 9cd38bc082f363d4d118fb7cf8fffad7 317 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 9 215 2.8E-74 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 SUPERFAMILY SSF56176 212 293 1.99E-20 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 SUPERFAMILY SSF54631 65 199 1.39E-30 T 28-03-2018 hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 SMART SM00116 78 127 16.0 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 SMART SM00116 139 187 0.11 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 Pfam PF03471 Transporter associated domain 214 285 2.8E-19 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 Gene3D G3DSA:3.10.580.10 50 196 5.9E-33 T 28-03-2018 hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 SMART SM01091 206 286 5.0E-24 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 Pfam PF00571 CBS domain 133 187 6.1E-6 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 Pfam PF00571 CBS domain 69 127 2.0E-4 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19840 7de222d77eba9013124cf00cac3ad6e2 295 Gene3D G3DSA:3.30.465.10 197 286 8.0E-24 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 419 447 1.3E-9 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 PIRSF PIRSF001604 9 684 4.4E-243 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:3.30.470.30 131 264 3.2E-52 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 343 358 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:2.40.50.140 329 402 3.2E-33 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:3.40.50.10190 627 684 2.0E-18 T 28-03-2018 IPR001357 BRCT domain hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SUPERFAMILY SSF56091 15 328 1.48E-114 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SMART SM00532 15 461 8.4E-253 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 608 679 1.1E-13 T 28-03-2018 IPR001357 BRCT domain hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SUPERFAMILY SSF50249 330 413 1.39E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 334 410 4.8E-34 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:1.10.150.20 568 626 5.9E-9 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 17 330 8.8E-124 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Pfam PF12826 Helix-hairpin-helix motif 523 586 1.8E-24 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SMART SM00278 493 512 180.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SMART SM00278 525 544 2600.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SMART SM00278 557 576 1.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SMART SM00278 459 478 240.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Hamap MF_01588 DNA ligase [ligA]. 18 680 53.293 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 127 156 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:1.10.150.20 445 516 4.0E-24 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 676 1.5E-256 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SMART SM00292 606 683 3.2E-16 T 28-03-2018 IPR001357 BRCT domain hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:1.10.150.20 517 567 6.9E-26 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SUPERFAMILY SSF52113 606 683 7.12E-20 T 28-03-2018 IPR001357 BRCT domain hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 SUPERFAMILY SSF47781 416 597 3.19E-61 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Pfam PF14520 Helix-hairpin-helix domain 459 515 4.6E-4 T 28-03-2018 hmeg3_RS09885 fdbf3cf20ee62c08b9420fc82857f860 694 Gene3D G3DSA:1.10.287.610 10 79 5.6E-22 T 28-03-2018 hmeg3_RS03530 ff8805dfcdcf94986129a82bec30fcf5 70 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 2.6E-22 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 hmeg3_RS03530 ff8805dfcdcf94986129a82bec30fcf5 70 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 67 22.946 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 hmeg3_RS03530 ff8805dfcdcf94986129a82bec30fcf5 70 Pfam PF02416 mttA/Hcf106 family 5 54 1.7E-15 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 67 83 8.9E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 43 59 8.9E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 138 156 8.9E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 PIRSF PIRSF005900 1 162 3.4E-48 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 Pfam PF00210 Ferritin-like domain 24 161 9.9E-28 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 ProSitePatterns PS00819 Dps protein family signature 2. 69 83 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 SUPERFAMILY SSF47240 8 161 5.8E-49 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 Gene3D G3DSA:1.20.1260.10 2 162 1.7E-51 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS21530 ecf643a6a750f4155d6a6658823d8b34 162 ProSitePatterns PS00818 Dps protein family signature 1. 43 59 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 320 3.5E-27 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 SUPERFAMILY SSF52283 2 135 6.24E-35 T 28-03-2018 hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 Gene3D G3DSA:3.40.50.720 1 113 3.3E-32 T 28-03-2018 hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 SUPERFAMILY SSF51735 101 289 7.37E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 Gene3D G3DSA:3.40.50.720 114 289 7.9E-53 T 28-03-2018 hmeg3_RS14570 f293e7df0770002735d87a62e4166dc6 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 288 1.2E-58 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 Gene3D G3DSA:1.10.10.10 3 88 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 Gene3D G3DSA:3.40.190.10 90 182 6.2E-14 T 28-03-2018 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 SUPERFAMILY SSF53850 90 287 9.23E-25 T 28-03-2018 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 SUPERFAMILY SSF46785 5 89 5.75E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 Pfam PF03466 LysR substrate binding domain 89 278 2.9E-21 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS06330 f9fdbba98b071cb05bb0b857cb9c7e83 299 Gene3D G3DSA:3.40.190.10 183 258 0.004 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Gene3D G3DSA:3.30.70.1430 585 676 3.2E-18 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82714 729 822 9.68E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82693 589 673 3.4E-13 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82693 40 133 1.57E-23 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Gene3D G3DSA:3.30.70.1430 40 141 1.2E-26 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82866 296 503 9.94E-45 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82714 189 272 4.32E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82693 153 188 3.84E-13 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82693 274 332 3.84E-13 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Gene3D G3DSA:3.30.2090.10 187 273 6.1E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Gene3D G3DSA:3.30.2090.10 728 823 1.1E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 477 500 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 635 649 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 3.0E-54 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Gene3D G3DSA:1.20.1640.10 274 505 4.1E-42 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Gene3D G3DSA:1.20.1640.10 824 1042 3.1E-41 T 28-03-2018 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 Pfam PF00873 AcrB/AcrD/AcrF family 4 1040 5.0E-272 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21100 bac33b24193b221aa9ebe9728d1632af 1074 SUPERFAMILY SSF82866 819 1042 4.97E-48 T 28-03-2018 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 SMART SM00228 404 480 1.8E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 SMART SM00228 294 376 2.6E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 60 485 5.1E-149 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Pfam PF13365 Trypsin-like peptidase domain 122 255 1.0E-34 T 28-03-2018 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Gene3D G3DSA:2.40.10.10 56 192 5.7E-36 T 28-03-2018 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Gene3D G3DSA:2.40.10.10 193 294 1.1E-35 T 28-03-2018 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Pfam PF13180 PDZ domain 405 487 2.7E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Pfam PF13180 PDZ domain 294 384 2.6E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 SUPERFAMILY SSF50156 252 376 2.63E-24 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 SUPERFAMILY SSF50156 404 489 7.1E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Gene3D G3DSA:2.30.42.10 399 490 6.4E-18 T 28-03-2018 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 Gene3D G3DSA:2.30.42.10 295 397 2.6E-26 T 28-03-2018 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 SUPERFAMILY SSF50494 58 285 6.63E-65 T 28-03-2018 IPR009003 Peptidase S1, PA clan hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 PRINTS PR00834 HtrA/DegQ protease family signature 152 172 9.6E-48 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 PRINTS PR00834 HtrA/DegQ protease family signature 334 346 9.6E-48 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 9.6E-48 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 9.6E-48 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 PRINTS PR00834 HtrA/DegQ protease family signature 131 143 9.6E-48 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS02030 dc8944d136e307d6f11c523cd72014cd 490 PRINTS PR00834 HtrA/DegQ protease family signature 192 216 9.6E-48 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS02610 3cc4bdf5d7e46175972fa60a2b3c26ec 198 Gene3D G3DSA:3.40.109.10 1 198 5.5E-37 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS02610 3cc4bdf5d7e46175972fa60a2b3c26ec 198 SUPERFAMILY SSF55469 6 196 2.49E-44 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS02610 3cc4bdf5d7e46175972fa60a2b3c26ec 198 Pfam PF00881 Nitroreductase family 76 164 2.3E-5 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 hmeg3_RS02610 3cc4bdf5d7e46175972fa60a2b3c26ec 198 Pfam PF00881 Nitroreductase family 19 62 1.7E-12 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 hmeg3_RS18005 f2fa3fd3781463e1a0cf0a7eac3ff8a5 228 Pfam PF00691 OmpA family 114 205 7.5E-14 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18005 f2fa3fd3781463e1a0cf0a7eac3ff8a5 228 Gene3D G3DSA:3.30.1330.60 86 228 6.5E-20 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18005 f2fa3fd3781463e1a0cf0a7eac3ff8a5 228 PRINTS PR01021 OMPA domain signature 162 178 3.2E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18005 f2fa3fd3781463e1a0cf0a7eac3ff8a5 228 PRINTS PR01021 OMPA domain signature 115 137 3.2E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18005 f2fa3fd3781463e1a0cf0a7eac3ff8a5 228 PRINTS PR01021 OMPA domain signature 147 162 3.2E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18005 f2fa3fd3781463e1a0cf0a7eac3ff8a5 228 SUPERFAMILY SSF103088 104 223 3.27E-18 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS23040 b0e7fc6ae6edad188bd1bfea74cf0744 323 SUPERFAMILY SSF103481 230 309 5.62E-7 T 28-03-2018 hmeg3_RS23040 b0e7fc6ae6edad188bd1bfea74cf0744 323 Pfam PF00892 EamA-like transporter family 161 308 3.8E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS23040 b0e7fc6ae6edad188bd1bfea74cf0744 323 Pfam PF00892 EamA-like transporter family 3 111 1.3E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS10290 d8eb0a04282ccfccaa3aedcf2646e0f1 164 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 128 4.5E-14 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 hmeg3_RS10290 d8eb0a04282ccfccaa3aedcf2646e0f1 164 Gene3D G3DSA:3.10.129.10 1 135 7.1E-31 T 28-03-2018 hmeg3_RS10290 d8eb0a04282ccfccaa3aedcf2646e0f1 164 SUPERFAMILY SSF54637 6 131 1.34E-31 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS10290 d8eb0a04282ccfccaa3aedcf2646e0f1 164 Pfam PF03061 Thioesterase superfamily 50 122 1.9E-12 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS05625 cdd50d11ce23f2d0c856f079d3a2af6e 155 Gene3D G3DSA:1.10.940.10 12 149 3.8E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 hmeg3_RS05625 cdd50d11ce23f2d0c856f079d3a2af6e 155 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 15 146 18.815 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 hmeg3_RS05625 cdd50d11ce23f2d0c856f079d3a2af6e 155 SUPERFAMILY SSF48013 15 147 1.44E-36 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 hmeg3_RS05625 cdd50d11ce23f2d0c856f079d3a2af6e 155 Pfam PF01029 NusB family 18 142 4.8E-28 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 hmeg3_RS05625 cdd50d11ce23f2d0c856f079d3a2af6e 155 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 17 144 3.3E-34 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 hmeg3_RS17475 49a0e1be693818ff8f91302afd39f7c5 126 Gene3D G3DSA:3.90.1590.10 2 121 4.4E-31 T 28-03-2018 hmeg3_RS17475 49a0e1be693818ff8f91302afd39f7c5 126 SUPERFAMILY SSF51316 3 103 2.72E-36 T 28-03-2018 IPR011057 Mss4-like hmeg3_RS17475 49a0e1be693818ff8f91302afd39f7c5 126 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 28 102 2.1E-11 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 hmeg3_RS18540 d911af664e7761538815a6cb8b1aef64 438 SUPERFAMILY SSF103473 9 435 5.62E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS18540 d911af664e7761538815a6cb8b1aef64 438 Gene3D G3DSA:1.20.1250.20 233 436 8.1E-29 T 28-03-2018 hmeg3_RS18540 d911af664e7761538815a6cb8b1aef64 438 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS18540 d911af664e7761538815a6cb8b1aef64 438 Pfam PF07690 Major Facilitator Superfamily 30 307 4.8E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18540 d911af664e7761538815a6cb8b1aef64 438 Gene3D G3DSA:1.20.1250.20 12 215 1.8E-35 T 28-03-2018 hmeg3_RS01395 32b67a1209386f41de25532feff9648b 315 Gene3D G3DSA:3.60.130.10 11 297 6.4E-69 T 28-03-2018 hmeg3_RS01395 32b67a1209386f41de25532feff9648b 315 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 17 286 2.7E-59 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS01395 32b67a1209386f41de25532feff9648b 315 SUPERFAMILY SSF51197 17 294 2.61E-81 T 28-03-2018 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:3.20.20.330 7 348 1.0E-109 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:1.10.288.10 1036 1108 3.2E-20 T 28-03-2018 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 SUPERFAMILY SSF51717 367 640 9.94E-93 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:3.20.20.20 355 653 1.3E-75 T 28-03-2018 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 PIRSF PIRSF000381 7 1220 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 957 1233 1.3E-118 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 SMART SM01018 664 751 1.9E-41 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Pfam PF02607 B12 binding domain 666 743 1.8E-24 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:3.10.196.10 1109 1248 1.7E-56 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Pfam PF02310 B12 binding domain 767 861 1.0E-17 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 SUPERFAMILY SSF82282 13 409 5.36E-111 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 TIGRFAM TIGR02082 metH: methionine synthase 18 1217 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Pfam PF00809 Pterin binding enzyme 370 608 1.1E-62 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 SUPERFAMILY SSF56507 925 1247 1.83E-119 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 SUPERFAMILY SSF47644 660 750 1.02E-26 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:3.40.50.280 762 918 6.0E-57 T 28-03-2018 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:1.10.1240.10 654 751 1.6E-36 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Gene3D G3DSA:1.10.288.10 958 1014 3.8E-22 T 28-03-2018 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 Pfam PF02574 Homocysteine S-methyltransferase 22 334 4.4E-76 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 hmeg3_RS02540 a4eaf733f187c862aaef268321a38855 1248 SUPERFAMILY SSF52242 763 917 5.76E-45 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 hmeg3_RS02035 3494d040389c236658feb12d7419b4bd 599 Pfam PF02254 TrkA-N domain 402 510 5.1E-22 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 hmeg3_RS02035 3494d040389c236658feb12d7419b4bd 599 Gene3D G3DSA:3.40.50.720 397 559 1.9E-19 T 28-03-2018 hmeg3_RS02035 3494d040389c236658feb12d7419b4bd 599 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 12 283 1.3E-81 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 hmeg3_RS02035 3494d040389c236658feb12d7419b4bd 599 Pfam PF00999 Sodium/hydrogen exchanger family 10 372 2.9E-65 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 hmeg3_RS02035 3494d040389c236658feb12d7419b4bd 599 Gene3D G3DSA:1.20.91.10 228 309 1.0E-13 T 28-03-2018 hmeg3_RS02035 3494d040389c236658feb12d7419b4bd 599 SUPERFAMILY SSF51735 401 531 1.27E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82866 812 1033 1.83E-45 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 1.2E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 PRINTS PR00702 Acriflavin resistance protein family signature 443 466 1.2E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 1.2E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.2E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 1.2E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 PRINTS PR00702 Acriflavin resistance protein family signature 44 62 1.2E-22 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Gene3D G3DSA:1.20.1640.10 313 508 3.1E-30 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Gene3D G3DSA:3.30.70.1430 46 150 9.4E-30 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Gene3D G3DSA:3.30.70.1320 232 312 6.3E-16 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82693 142 188 1.26E-18 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82693 274 325 1.26E-18 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Gene3D G3DSA:1.20.1640.10 820 1031 4.4E-34 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82693 46 141 3.49E-18 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Gene3D G3DSA:3.30.2090.10 729 813 9.5E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82693 575 682 1.52E-8 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82714 730 811 2.75E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Pfam PF00873 AcrB/AcrD/AcrF family 12 1028 8.6E-158 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82866 303 495 5.1E-33 T 28-03-2018 hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 SUPERFAMILY SSF82714 191 271 4.97E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS03900 551b79b2cbfcd873d8c4a53e3fa5eafe 1050 Gene3D G3DSA:3.30.70.1430 576 682 1.2E-13 T 28-03-2018 hmeg3_RS17410 50b9843b845eef8c76062dfe8d32fa7e 316 SUPERFAMILY SSF51430 2 314 5.76E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS17410 50b9843b845eef8c76062dfe8d32fa7e 316 Gene3D G3DSA:3.20.20.100 3 316 1.1E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS17410 50b9843b845eef8c76062dfe8d32fa7e 316 Pfam PF00248 Aldo/keto reductase family 15 313 3.8E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 608 8.6E-73 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 SUPERFAMILY SSF56601 252 612 9.63E-102 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 Gene3D G3DSA:3.40.710.10 248 617 2.2E-92 T 28-03-2018 hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 SUPERFAMILY SSF56519 53 251 6.28E-50 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 17 612 9.6E-239 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 237 1.2E-43 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 hmeg3_RS00730 089f342828ee61797ac8b6e6863baf94 645 Gene3D G3DSA:3.90.1310.10 30 247 5.0E-52 T 28-03-2018 hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 Gene3D G3DSA:1.10.357.10 69 212 1.5E-12 T 28-03-2018 hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 SUPERFAMILY SSF46689 19 88 1.39E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 SUPERFAMILY SSF48498 95 217 8.9E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 Gene3D G3DSA:1.10.10.60 2 68 7.6E-13 T 28-03-2018 hmeg3_RS20950 fd4b378c05351c7c69606849fd137d3e 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 1.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 Gene3D G3DSA:3.20.20.80 62 511 5.4E-119 T 28-03-2018 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 Gene3D G3DSA:1.10.510.10 812 1102 8.4E-14 T 28-03-2018 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 SUPERFAMILY SSF56112 806 865 2.24E-13 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 SUPERFAMILY SSF56112 910 1112 2.24E-13 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 616 1150 3.2E-163 T 28-03-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 Pfam PF16657 Maltogenic Amylase, C-terminal domain 512 596 5.3E-28 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 57 599 6.6E-279 T 28-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 SMART SM00642 65 464 1.2E-97 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 SUPERFAMILY SSF51445 55 375 1.39E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 SUPERFAMILY SSF51445 402 509 1.39E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 Pfam PF00128 Alpha amylase, catalytic domain 80 433 2.7E-72 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 Gene3D G3DSA:2.60.40.1180 512 610 3.8E-24 T 28-03-2018 hmeg3_RS11325 97d6dddab8e19845a06fff8196557c77 1158 SUPERFAMILY SSF51011 516 599 1.04E-14 T 28-03-2018 hmeg3_RS07150 5e987fb87a1502360930ea1c79b10935 381 Pfam PF05230 MASE2 domain 49 137 4.0E-27 T 28-03-2018 IPR007894 MASE2 hmeg3_RS07150 5e987fb87a1502360930ea1c79b10935 381 SUPERFAMILY SSF55073 224 377 1.02E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS07150 5e987fb87a1502360930ea1c79b10935 381 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 216 378 3.6E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07150 5e987fb87a1502360930ea1c79b10935 381 Pfam PF00990 Diguanylate cyclase, GGDEF domain 220 374 2.6E-43 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07150 5e987fb87a1502360930ea1c79b10935 381 SMART SM00267 208 379 3.8E-53 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07150 5e987fb87a1502360930ea1c79b10935 381 Gene3D G3DSA:3.30.70.270 209 380 1.2E-51 T 28-03-2018 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 SUPERFAMILY SSF55347 134 353 4.48E-68 T 28-03-2018 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 260 274 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 3 365 1.9E-208 T 28-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 366 31.954 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 SMART SM00859 3 122 1.8E-30 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 122 7.9E-27 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 Gene3D G3DSA:3.30.360.10 146 348 2.2E-53 T 28-03-2018 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 SUPERFAMILY SSF51735 2 147 2.91E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 PIRSF PIRSF000148 1 368 1.7E-62 T 28-03-2018 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 352 2.0E-47 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS17235 29b96262d433d761b066cc45c8404987 368 Gene3D G3DSA:3.40.50.720 1 145 8.4E-21 T 28-03-2018 hmeg3_RS20365 7901aad4005101cf92a95f31f2f37011 213 Pfam PF01712 Deoxynucleoside kinase 9 201 8.2E-42 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain hmeg3_RS20365 7901aad4005101cf92a95f31f2f37011 213 SUPERFAMILY SSF52540 5 204 9.27E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20365 7901aad4005101cf92a95f31f2f37011 213 PIRSF PIRSF000705 1 208 3.3E-64 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 hmeg3_RS20365 7901aad4005101cf92a95f31f2f37011 213 Gene3D G3DSA:3.40.50.300 3 211 4.8E-39 T 28-03-2018 hmeg3_RS06090 ef9b5e305573d081cd2ebb05017347ed 352 SUPERFAMILY SSF53850 45 276 1.8E-23 T 28-03-2018 hmeg3_RS06090 ef9b5e305573d081cd2ebb05017347ed 352 Gene3D G3DSA:3.40.190.10 41 147 8.5E-9 T 28-03-2018 hmeg3_RS06090 ef9b5e305573d081cd2ebb05017347ed 352 Pfam PF13379 NMT1-like family 43 278 2.4E-26 T 28-03-2018 hmeg3_RS06090 ef9b5e305573d081cd2ebb05017347ed 352 Gene3D G3DSA:3.40.190.10 148 332 1.3E-24 T 28-03-2018 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 93 22.557 T 28-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 179 2.4E-42 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 SUPERFAMILY SSF50715 2 190 1.29E-55 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 Gene3D G3DSA:2.40.240.10 1 93 7.7E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 Pfam PF01386 Ribosomal L25p family 5 90 9.5E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 30.909 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 183 8.3E-30 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 Gene3D G3DSA:2.170.120.20 97 188 1.0E-29 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain hmeg3_RS04295 a263571e6f13f92f705241faed1d8ae6 202 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 1.0E-37 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 SMART SM00387 373 475 9.2E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 474 1.3E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 Gene3D G3DSA:1.10.287.130 247 331 1.1E-7 T 28-03-2018 hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 Gene3D G3DSA:3.30.565.10 333 476 1.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 SMART SM00304 202 256 0.0013 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 SUPERFAMILY SSF47384 262 334 2.16E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 333 8.3E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 SMART SM00388 269 335 2.0E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02295 a3d30348d405fe72d31e55d2cea70274 478 SUPERFAMILY SSF55874 343 468 1.83E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 SUPERFAMILY SSF48557 6 457 7.54E-119 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 ProSitePatterns PS00163 Fumarate lyases signature. 278 287 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 457 2.5E-150 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 1.4E-23 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00149 Fumarate lyase superfamily signature 278 294 1.4E-23 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00149 Fumarate lyase superfamily signature 234 261 1.4E-23 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 1.4E-23 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 Pfam PF14698 Argininosuccinate lyase C-terminal 366 434 1.1E-21 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 Hamap MF_00006 Argininosuccinate lyase [argH]. 5 456 36.685 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 Gene3D G3DSA:1.10.275.10 5 109 4.7E-22 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 Pfam PF00206 Lyase 10 303 9.6E-53 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 Gene3D G3DSA:1.10.40.30 378 435 5.5E-23 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 Gene3D G3DSA:1.20.200.10 110 377 9.3E-75 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 2.7E-51 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00145 Argininosuccinate lyase family signature 196 212 2.7E-51 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00145 Argininosuccinate lyase family signature 278 294 2.7E-51 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00145 Argininosuccinate lyase family signature 313 332 2.7E-51 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00145 Argininosuccinate lyase family signature 234 258 2.7E-51 T 28-03-2018 hmeg3_RS23435 b4cbc4ace9ef856f286def611c86e494 483 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 2.7E-51 T 28-03-2018 hmeg3_RS01010 c9a6dd7135be051839f465541bbf9dc9 183 Pfam PF01613 Flavin reductase like domain 18 159 3.1E-21 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS01010 c9a6dd7135be051839f465541bbf9dc9 183 Gene3D G3DSA:2.30.110.10 2 177 3.5E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS01010 c9a6dd7135be051839f465541bbf9dc9 183 SUPERFAMILY SSF50475 7 169 1.18E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS01010 c9a6dd7135be051839f465541bbf9dc9 183 SMART SM00903 16 166 2.4E-11 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS07950 f43c42bffa4987394306ff101a4d5e44 293 Gene3D G3DSA:1.10.3470.10 12 281 1.7E-22 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS07950 f43c42bffa4987394306ff101a4d5e44 293 SUPERFAMILY SSF81345 16 274 7.19E-25 T 28-03-2018 IPR029022 ABC transporter, BtuC-like hmeg3_RS07950 f43c42bffa4987394306ff101a4d5e44 293 Pfam PF00950 ABC 3 transport family 18 276 9.6E-54 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 hmeg3_RS06850 e17e8628ed8cb5227e5ee3578f403569 161 SUPERFAMILY SSF89963 2 87 1.1E-30 T 28-03-2018 IPR007551 Protein of unknown function DUF520 hmeg3_RS06850 e17e8628ed8cb5227e5ee3578f403569 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 1.9E-66 T 28-03-2018 IPR007551 Protein of unknown function DUF520 hmeg3_RS06850 e17e8628ed8cb5227e5ee3578f403569 161 SUPERFAMILY SSF89963 89 161 5.23E-28 T 28-03-2018 IPR007551 Protein of unknown function DUF520 hmeg3_RS06850 e17e8628ed8cb5227e5ee3578f403569 161 Gene3D G3DSA:3.30.70.990 10 95 2.3E-32 T 28-03-2018 IPR035570 UPF0234 N-terminal domain hmeg3_RS06850 e17e8628ed8cb5227e5ee3578f403569 161 Gene3D G3DSA:3.30.70.860 96 160 1.7E-32 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain hmeg3_RS06850 e17e8628ed8cb5227e5ee3578f403569 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 27.796 T 28-03-2018 IPR007551 Protein of unknown function DUF520 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 SUPERFAMILY SSF53738 3 184 5.49E-49 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Gene3D G3DSA:3.40.120.10 271 375 2.1E-28 T 28-03-2018 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 444 1.1E-183 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 138 4.2E-44 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 SUPERFAMILY SSF53738 159 259 3.45E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 SUPERFAMILY SSF55957 360 444 1.7E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 442 46.108 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Gene3D G3DSA:3.30.310.50 376 445 1.1E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 443 1.6E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 99 108 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Gene3D G3DSA:3.40.120.10 3 157 1.1E-51 T 28-03-2018 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 367 1.9E-30 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Gene3D G3DSA:3.40.120.10 159 270 1.0E-29 T 28-03-2018 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 177 196 9.0E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 9.0E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 9.0E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 SUPERFAMILY SSF53738 261 367 5.1E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS06555 70d7d60186ce7e8ac0d368392d3d21eb 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 257 1.3E-17 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS03870 1ef90e3fa739d7dc78b3e5d7fa45af93 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 308 2.3E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03870 1ef90e3fa739d7dc78b3e5d7fa45af93 312 SUPERFAMILY SSF161098 105 292 3.16E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03870 1ef90e3fa739d7dc78b3e5d7fa45af93 312 Gene3D G3DSA:1.10.3720.10 30 300 1.7E-41 T 28-03-2018 hmeg3_RS03870 1ef90e3fa739d7dc78b3e5d7fa45af93 312 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 81 3.6E-10 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS17085 6e0d144a8d48fc7811ff796313965f64 371 Pfam PF13478 XdhC Rossmann domain 193 335 4.1E-36 T 28-03-2018 IPR027051 XdhC Rossmann domain hmeg3_RS17085 6e0d144a8d48fc7811ff796313965f64 371 Pfam PF02625 XdhC and CoxI family 16 69 1.8E-16 T 28-03-2018 IPR003777 XdhC- CoxI hmeg3_RS17085 6e0d144a8d48fc7811ff796313965f64 371 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 19 336 5.2E-94 T 28-03-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC hmeg3_RS17085 6e0d144a8d48fc7811ff796313965f64 371 Gene3D G3DSA:3.40.50.20 191 279 1.9E-4 T 28-03-2018 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 Gene3D G3DSA:3.40.190.10 182 263 2.5E-16 T 28-03-2018 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 Pfam PF03466 LysR substrate binding domain 92 293 1.8E-34 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 SUPERFAMILY SSF53850 94 295 5.97E-38 T 28-03-2018 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 Gene3D G3DSA:3.40.190.10 96 181 1.9E-18 T 28-03-2018 hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 SUPERFAMILY SSF46785 6 89 1.15E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 Gene3D G3DSA:1.10.10.10 6 90 7.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24090 bc7cd74722cdb0574cfebea8fd25cbfb 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 2.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23055 a5c57b47a37d975ff2eafc7f011980db 405 Gene3D G3DSA:1.20.1250.20 204 398 2.0E-15 T 28-03-2018 hmeg3_RS23055 a5c57b47a37d975ff2eafc7f011980db 405 Pfam PF07690 Major Facilitator Superfamily 33 303 2.4E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS23055 a5c57b47a37d975ff2eafc7f011980db 405 Gene3D G3DSA:1.20.1250.20 4 201 4.0E-20 T 28-03-2018 hmeg3_RS23055 a5c57b47a37d975ff2eafc7f011980db 405 SUPERFAMILY SSF103473 17 396 3.66E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 SUPERFAMILY SSF53244 324 462 1.52E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Gene3D G3DSA:3.40.1190.10 96 322 8.2E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 SUPERFAMILY SSF63418 4 103 3.92E-25 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 463 32.287 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Gene3D G3DSA:3.40.1390.10 1 95 9.6E-29 T 28-03-2018 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Pfam PF08245 Mur ligase middle domain 111 304 9.1E-41 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 393 7.3E-13 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Pfam PF01225 Mur ligase family, catalytic domain 29 101 2.6E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 SUPERFAMILY SSF53623 105 322 4.32E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 Gene3D G3DSA:3.90.190.20 324 474 1.2E-41 T 28-03-2018 hmeg3_RS22030 c1266fd4b0d80a07cbcef082ddc6f07f 478 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 462 2.2E-126 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS01360 9b239cde4b4a6b41ecca98a673deb450 398 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 376 1.6E-35 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01360 9b239cde4b4a6b41ecca98a673deb450 398 Gene3D G3DSA:3.30.70.270 205 381 1.6E-45 T 28-03-2018 hmeg3_RS01360 9b239cde4b4a6b41ecca98a673deb450 398 SUPERFAMILY SSF55073 226 378 4.79E-38 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS01360 9b239cde4b4a6b41ecca98a673deb450 398 SMART SM00267 210 380 1.1E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01360 9b239cde4b4a6b41ecca98a673deb450 398 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 218 378 1.8E-35 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 Gene3D G3DSA:1.10.287.1060 240 325 0.025 T 28-03-2018 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 186 1.4E-29 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 SUPERFAMILY SSF58104 233 515 1.7E-76 T 28-03-2018 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 Gene3D G3DSA:1.20.120.30 26 187 1.9E-17 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 SMART SM00283 266 513 1.7E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 SMART SM00304 213 265 7.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 Pfam PF00672 HAMP domain 215 260 1.5E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 Gene3D G3DSA:1.10.287.950 326 517 1.5E-48 T 28-03-2018 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 7.4E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 7.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 7.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 7.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 7.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11515 3c926e687f9135ecbfa80a748d132a79 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 7.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 SUPERFAMILY SSF46589 1 112 1.62E-29 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 PIRSF PIRSF001529 1 432 4.3E-179 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 231 406 3.0E-38 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.0E-30 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 PRINTS PR00981 Seryl-tRNA synthetase signature 341 357 9.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 PRINTS PR00981 Seryl-tRNA synthetase signature 359 375 9.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 PRINTS PR00981 Seryl-tRNA synthetase signature 284 297 9.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 PRINTS PR00981 Seryl-tRNA synthetase signature 324 337 9.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 PRINTS PR00981 Seryl-tRNA synthetase signature 272 284 9.3E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 SUPERFAMILY SSF55681 116 425 3.48E-102 T 28-03-2018 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 Gene3D G3DSA:1.10.287.40 2 104 1.6E-24 T 28-03-2018 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 429 39.734 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 Gene3D G3DSA:3.30.930.10 105 432 2.7E-95 T 28-03-2018 hmeg3_RS16805 694a4e4d1b4085c5f2690619a3eb3bbc 432 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 424 2.0E-164 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 SUPERFAMILY SSF81901 11 161 1.22E-10 T 28-03-2018 hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Gene3D G3DSA:2.60.40.1180 296 370 5.8E-6 T 28-03-2018 hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Gene3D G3DSA:2.60.40.1180 371 405 0.0083 T 28-03-2018 hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Gene3D G3DSA:2.60.40.1180 3 144 2.4E-8 T 28-03-2018 hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 SUPERFAMILY SSF81901 253 400 1.14E-16 T 28-03-2018 hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Pfam PF08238 Sel1 repeat 18 53 2.1E-6 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Pfam PF08238 Sel1 repeat 357 392 6.0E-4 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Pfam PF08238 Sel1 repeat 78 90 240.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 Pfam PF08238 Sel1 repeat 327 354 6.7 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 SMART SM00671 356 392 0.084 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 SMART SM00671 320 355 0.16 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS18035 eb12757d3b864475432dfac92494d3e2 529 SMART SM00671 18 54 4.3E-6 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS20670 a6fe317a39440a0c734fbfb31a583e05 347 SUPERFAMILY SSF53474 146 329 5.52E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20670 a6fe317a39440a0c734fbfb31a583e05 347 Gene3D G3DSA:3.40.50.1820 27 340 9.6E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SUPERFAMILY SSF48452 16 177 2.37E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Pfam PF13432 Tetratricopeptide repeat 26 81 6.0E-4 T 28-03-2018 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Pfam PF13432 Tetratricopeptide repeat 87 147 4.2E-9 T 28-03-2018 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Gene3D G3DSA:3.40.50.150 263 439 3.0E-21 T 28-03-2018 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SUPERFAMILY SSF53335 243 444 2.26E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Gene3D G3DSA:1.10.150.200 159 192 0.048 T 28-03-2018 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Gene3D G3DSA:1.25.40.10 10 101 2.2E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Gene3D G3DSA:1.25.40.10 102 158 7.6E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Gene3D G3DSA:1.25.40.10 193 240 0.0038 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 Pfam PF08241 Methyltransferase domain 285 377 1.0E-10 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SMART SM00028 48 81 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SMART SM00028 184 217 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SMART SM00028 116 149 3.3E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SMART SM00028 82 115 0.0011 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SMART SM00028 150 183 480.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS13900 3feed1ba382bc7f54cf8e011b4a18cf4 445 SMART SM00028 14 47 31.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 4 464 39.158 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 Gene3D G3DSA:1.20.120.640 311 395 2.8E-17 T 28-03-2018 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 Pfam PF09190 DALR domain 348 403 2.6E-18 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 SUPERFAMILY SSF52374 4 317 1.51E-100 T 28-03-2018 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 317 5.1E-134 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 27 38 1.9E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 1.9E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 63 72 1.9E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 1.9E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 SUPERFAMILY SSF47323 321 463 2.88E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 Gene3D G3DSA:3.40.50.620 1 310 1.5E-93 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 SMART SM00840 348 403 3.6E-24 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 hmeg3_RS09005 9f16ff54fdba233e6270a2d13b288a85 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 1.3E-173 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 Pfam PF08245 Mur ligase middle domain 485 698 3.0E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 Gene3D G3DSA:3.30.1490.20 202 287 1.7E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 217 303 4.6E-8 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 Gene3D G3DSA:3.30.470.20 288 459 2.4E-21 T 28-03-2018 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 SUPERFAMILY SSF53623 480 714 1.01E-27 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 SMART SM01209 216 349 0.0068 T 28-03-2018 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 SUPERFAMILY SSF56059 217 493 2.19E-34 T 28-03-2018 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 5 721 0.0 T 28-03-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 hmeg3_RS09905 6203ba9b7623eeb09349d6ad85f0087f 732 Gene3D G3DSA:3.40.1190.10 467 717 2.2E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 Pfam PF00106 short chain dehydrogenase 6 196 5.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 181 8.7E-4 T 28-03-2018 hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 SUPERFAMILY SSF51735 1 235 3.62E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 Gene3D G3DSA:3.40.50.720 1 215 6.4E-50 T 28-03-2018 hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01520 f51b487c4ebf71cf96df74bf1a1bc7b5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 PIRSF PIRSF000103 1 289 2.8E-67 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 SUPERFAMILY SSF51735 3 168 6.26E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 Gene3D G3DSA:1.10.1040.10 165 290 2.4E-34 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 SUPERFAMILY SSF48179 166 288 3.29E-38 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 Gene3D G3DSA:3.40.50.720 1 164 1.3E-29 T 28-03-2018 hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 286 1.3E-37 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 hmeg3_RS03110 cf8aa7629332e375a71dc45603f7f6de 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 161 3.2E-38 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SUPERFAMILY SSF47384 170 210 5.69E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 146 7.3E-12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 Pfam PF08447 PAS fold 47 131 3.5E-21 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 1.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 1.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 1.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 1.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SUPERFAMILY SSF55785 35 141 2.9E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SUPERFAMILY SSF55874 264 424 1.15E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SMART SM00388 175 278 0.0092 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SMART SM00387 318 426 8.6E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 Gene3D G3DSA:3.30.565.10 276 426 8.4E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SMART SM00086 97 139 4.9E-9 T 28-03-2018 IPR001610 PAC motif hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 425 8.5E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 Gene3D G3DSA:1.10.287.130 170 274 1.8E-9 T 28-03-2018 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 Pfam PF00512 His Kinase A (phospho-acceptor) domain 176 275 2.9E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 Gene3D G3DSA:3.30.450.20 16 169 6.8E-28 T 28-03-2018 hmeg3_RS03610 e43e2afed9d4a52be0f71526c58a0a0d 426 SMART SM00091 22 92 5.3E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS24200 bf7f2438779f0ebf3c1f4dffac0ba317 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 282 6.8E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS24200 bf7f2438779f0ebf3c1f4dffac0ba317 294 Gene3D G3DSA:1.10.3470.10 3 286 2.2E-42 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 PRINTS PR00045 Sigma-54 factor signature 393 405 4.5E-29 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 PRINTS PR00045 Sigma-54 factor signature 467 485 4.5E-29 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 PRINTS PR00045 Sigma-54 factor signature 409 420 4.5E-29 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 PRINTS PR00045 Sigma-54 factor signature 205 222 4.5E-29 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 381 400 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 Pfam PF04552 Sigma-54, DNA binding domain 338 491 5.9E-66 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 Pfam PF04963 Sigma-54 factor, core binding domain 132 323 4.6E-57 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 472 479 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 PIRSF PIRSF000774 1 493 1.5E-152 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 491 7.2E-140 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 48 1.2E-15 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04025 9c76548733896f9f24687dbccf13bb6d 493 Gene3D G3DSA:1.10.10.10 340 427 3.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05690 cba5365d158d08a3ccd56cca84fd744f 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 131 2.1E-33 T 28-03-2018 hmeg3_RS05690 cba5365d158d08a3ccd56cca84fd744f 179 SUPERFAMILY SSF54593 8 147 2.96E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS05690 cba5365d158d08a3ccd56cca84fd744f 179 Gene3D G3DSA:3.10.180.10 3 164 7.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS02890 c1825309fc1537e4aa3c0bef6043cd02 280 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 6 278 9.7E-100 T 28-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 hmeg3_RS02890 c1825309fc1537e4aa3c0bef6043cd02 280 Pfam PF02219 Methylenetetrahydrofolate reductase 4 278 1.1E-88 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 hmeg3_RS02890 c1825309fc1537e4aa3c0bef6043cd02 280 SUPERFAMILY SSF51730 4 278 5.69E-95 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like hmeg3_RS02890 c1825309fc1537e4aa3c0bef6043cd02 280 Gene3D G3DSA:3.20.20.220 2 280 4.7E-95 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 SUPERFAMILY SSF54909 67 152 2.41E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 SMART SM00344 7 116 1.5E-37 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 Gene3D G3DSA:1.10.10.10 1 55 1.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 SUPERFAMILY SSF46785 6 67 9.11E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 7.4E-17 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 Gene3D G3DSA:3.30.70.920 60 144 2.0E-23 T 28-03-2018 hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 3.0E-15 T 28-03-2018 hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.9E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS17805 c2c8fe573220fcd2343ef30f66857df1 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.9E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14405 c4559e7ee828208a6c624b5bc6ed5bea 395 Pfam PF13416 Bacterial extracellular solute-binding protein 57 341 6.5E-30 T 28-03-2018 hmeg3_RS14405 c4559e7ee828208a6c624b5bc6ed5bea 395 Gene3D G3DSA:3.40.190.10 173 324 1.2E-17 T 28-03-2018 hmeg3_RS14405 c4559e7ee828208a6c624b5bc6ed5bea 395 Gene3D G3DSA:3.40.190.10 38 172 1.1E-13 T 28-03-2018 hmeg3_RS14405 c4559e7ee828208a6c624b5bc6ed5bea 395 SUPERFAMILY SSF53850 39 357 2.03E-29 T 28-03-2018 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 313 2.4E-106 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Gene3D G3DSA:1.10.150.20 243 325 3.4E-28 T 28-03-2018 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 150 5.8E-24 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 SUPERFAMILY SSF47789 248 321 3.92E-27 T 28-03-2018 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 248 305 1.0E-24 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 SUPERFAMILY SSF56553 50 174 3.79E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 314 35.599 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 224 1.4E-21 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 SMART SM00662 20 230 2.6E-99 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 323 2.0E-34 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Gene3D G3DSA:3.30.1360.10 1 103 1.6E-15 T 28-03-2018 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 Gene3D G3DSA:3.30.1360.10 108 227 2.4E-31 T 28-03-2018 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 SUPERFAMILY SSF55257 175 228 1.86E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22730 d93835a3d952dda9de197bccd15a9ba4 325 SUPERFAMILY SSF55257 2 50 1.86E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 Gene3D G3DSA:3.40.50.1360 1 137 9.1E-42 T 28-03-2018 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 SUPERFAMILY SSF100950 1 146 1.26E-45 T 28-03-2018 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 Gene3D G3DSA:3.30.70.260 138 200 8.8E-25 T 28-03-2018 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 SUPERFAMILY SSF75445 126 202 1.07E-22 T 28-03-2018 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 221 32.398 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 217 1.3E-58 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS17790 d8436e450ddeb2bbbdd0269a436fc297 223 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 219 4.4E-69 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 Pfam PF00890 FAD binding domain 4 392 7.8E-99 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 SUPERFAMILY SSF46977 423 521 4.71E-32 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 2 518 3.9E-194 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 Pfam PF02910 Fumarate reductase flavoprotein C-term 439 519 7.3E-15 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 6.7E-9 T 28-03-2018 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.7E-9 T 28-03-2018 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 SUPERFAMILY SSF56425 232 353 1.32E-38 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 SUPERFAMILY SSF51905 2 249 5.14E-76 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 SUPERFAMILY SSF51905 356 446 5.14E-76 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 PIRSF PIRSF000171 338 530 1.6E-12 T 28-03-2018 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 PIRSF PIRSF000171 1 252 2.0E-20 T 28-03-2018 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 Gene3D G3DSA:1.20.58.100 437 532 7.2E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS10175 e45e2aa308132c2ab24b1dc656d63d82 533 Gene3D G3DSA:3.50.50.60 1 436 8.8E-79 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16960 e962f9bb32fd57a38aa10026868eacc0 242 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16960 e962f9bb32fd57a38aa10026868eacc0 242 Pfam PF00005 ABC transporter 26 170 2.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16960 e962f9bb32fd57a38aa10026868eacc0 242 Gene3D G3DSA:3.40.50.300 4 242 1.5E-54 T 28-03-2018 hmeg3_RS16960 e962f9bb32fd57a38aa10026868eacc0 242 SUPERFAMILY SSF52540 7 240 6.06E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16960 e962f9bb32fd57a38aa10026868eacc0 242 SMART SM00382 34 221 6.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16960 e962f9bb32fd57a38aa10026868eacc0 242 PIRSF PIRSF039137 5 242 5.1E-104 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 hmeg3_RS18100 f5ac873800ee12169969ae6025543070 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 142 2.4E-27 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 Pfam PF01580 FtsK/SpoIIIE family 393 602 3.6E-66 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 SUPERFAMILY SSF52540 375 674 3.05E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 Gene3D G3DSA:1.10.10.10 709 763 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 Pfam PF09397 Ftsk gamma domain 709 769 3.8E-26 T 28-03-2018 IPR018541 FtsK gamma domain hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 SMART SM00843 707 772 2.1E-37 T 28-03-2018 IPR018541 FtsK gamma domain hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 SUPERFAMILY SSF46785 707 773 3.88E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 26 207 2.9E-48 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 SMART SM00382 428 623 0.0077 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16830 287864ee951f4383e1fe5f02dc5b6fd2 776 Gene3D G3DSA:3.40.50.300 234 640 5.5E-55 T 28-03-2018 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 Gene3D G3DSA:3.30.70.260 339 412 1.8E-22 T 28-03-2018 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 411 7.0E-112 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 Pfam PF01842 ACT domain 276 333 2.8E-10 T 28-03-2018 IPR002912 ACT domain hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 Gene3D G3DSA:3.40.1160.10 1 244 1.6E-71 T 28-03-2018 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 Pfam PF13840 ACT domain 349 409 1.1E-16 T 28-03-2018 IPR027795 GATS-like ACT domain hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 SUPERFAMILY SSF53633 4 250 4.32E-72 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 PIRSF PIRSF000726 1 62 4.1E-20 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 PIRSF PIRSF000726 53 417 6.6E-138 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 SUPERFAMILY SSF55021 257 335 9.16E-19 T 28-03-2018 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 Pfam PF00696 Amino acid kinase family 4 229 1.7E-49 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 Gene3D G3DSA:3.30.70.260 245 338 8.5E-25 T 28-03-2018 hmeg3_RS09750 66cc72648c28dd010f142f54548318a2 417 SUPERFAMILY SSF55021 341 414 2.54E-24 T 28-03-2018 hmeg3_RS03875 a559fcb970ea7d5c164b0a616d30abb0 336 Pfam PF00005 ABC transporter 25 182 3.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03875 a559fcb970ea7d5c164b0a616d30abb0 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 300 4.4E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS03875 a559fcb970ea7d5c164b0a616d30abb0 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 321 8.5E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS03875 a559fcb970ea7d5c164b0a616d30abb0 336 SUPERFAMILY SSF52540 4 253 2.66E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03875 a559fcb970ea7d5c164b0a616d30abb0 336 SMART SM00382 33 232 9.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03875 a559fcb970ea7d5c164b0a616d30abb0 336 Gene3D G3DSA:3.40.50.300 1 333 5.4E-70 T 28-03-2018 hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 Gene3D G3DSA:3.30.450.40 83 266 1.7E-44 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 SUPERFAMILY SSF55781 83 262 3.73E-42 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 Gene3D G3DSA:1.10.10.10 4 78 3.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 SMART SM00346 17 107 3.3E-27 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 Pfam PF09339 IclR helix-turn-helix domain 20 70 2.6E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 SUPERFAMILY SSF46785 17 90 3.42E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00120 a6914c4e9ea1cdeb88f291f954a51ede 277 Pfam PF01614 Bacterial transcriptional regulator 138 259 3.8E-20 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS09835 c8f60f46cadac80d36e39d0971d7e63b 268 SMART SM00062 39 260 1.6E-77 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09835 c8f60f46cadac80d36e39d0971d7e63b 268 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS09835 c8f60f46cadac80d36e39d0971d7e63b 268 Gene3D G3DSA:3.40.190.10 139 213 7.5E-19 T 28-03-2018 hmeg3_RS09835 c8f60f46cadac80d36e39d0971d7e63b 268 SUPERFAMILY SSF53850 12 260 3.17E-70 T 28-03-2018 hmeg3_RS09835 c8f60f46cadac80d36e39d0971d7e63b 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 258 1.3E-63 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09835 c8f60f46cadac80d36e39d0971d7e63b 268 Gene3D G3DSA:3.40.190.10 29 138 2.6E-36 T 28-03-2018 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Pfam PF12848 ABC transporter 224 296 1.0E-8 T 28-03-2018 IPR032781 ABC-transporter extension domain hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Gene3D G3DSA:3.40.50.300 292 551 1.1E-55 T 28-03-2018 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 SUPERFAMILY SSF52540 4 232 6.03E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 SMART SM00382 28 230 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 SMART SM00382 344 514 3.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Pfam PF00005 ABC transporter 337 469 6.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Pfam PF00005 ABC transporter 19 185 1.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Gene3D G3DSA:3.40.50.300 72 291 1.0E-42 T 28-03-2018 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 SUPERFAMILY SSF52540 313 510 1.68E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Pfam PF16326 ABC transporter C-terminal domain 564 632 1.2E-18 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 hmeg3_RS06590 dcac27891875252aefd3eaf823e16893 637 Gene3D G3DSA:3.40.50.300 9 71 8.1E-7 T 28-03-2018 hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 Pfam PF08447 PAS fold 30 116 2.9E-16 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 SUPERFAMILY SSF55785 11 124 2.62E-20 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 Gene3D G3DSA:3.30.450.20 4 139 1.8E-23 T 28-03-2018 hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 136 304 5.1E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 SMART SM00086 80 122 9.2E-6 T 28-03-2018 IPR001610 PAC motif hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 Pfam PF00990 Diguanylate cyclase, GGDEF domain 141 300 2.6E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 SMART SM00267 129 305 1.1E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 129 3.1E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 SUPERFAMILY SSF55073 145 303 4.0E-43 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS10755 eac5ab9c2b3e24227bfeddfeccece3c4 306 Gene3D G3DSA:3.30.70.270 140 306 2.1E-47 T 28-03-2018 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 18 35 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 26 36 3.0E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 13 25 3.0E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 328 334 3.0E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 42 54 3.0E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 87 99 3.0E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 361 373 3.0E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 Pfam PF01266 FAD dependent oxidoreductase 14 337 5.2E-52 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 366 376 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 394 491 5.4E-10 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 SUPERFAMILY SSF51905 327 384 3.4E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 SUPERFAMILY SSF51905 11 275 3.4E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 Gene3D G3DSA:3.50.50.60 2 407 5.0E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS15200 7c0cff66cbb84f37935db942de73c58e 512 SUPERFAMILY SSF54373 241 334 5.89E-7 T 28-03-2018 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Pfam PF13426 PAS domain 29 131 5.0E-13 T 28-03-2018 IPR000014 PAS domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SUPERFAMILY SSF52172 396 509 2.7E-25 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 261 378 3.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Gene3D G3DSA:3.40.50.2300 395 510 6.7E-23 T 28-03-2018 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SUPERFAMILY SSF55874 209 379 6.16E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 323 6.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 337 6.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 6.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 6.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Pfam PF00072 Response regulator receiver domain 397 507 2.2E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SMART SM00091 16 83 4.2E-4 T 28-03-2018 IPR000014 PAS domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Gene3D G3DSA:3.30.450.20 12 143 8.6E-27 T 28-03-2018 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SMART SM00448 395 507 2.4E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Gene3D G3DSA:1.10.287.130 144 215 2.7E-6 T 28-03-2018 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SMART SM00387 260 380 3.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 Gene3D G3DSA:3.30.565.10 219 390 6.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SUPERFAMILY SSF55785 27 131 2.44E-23 T 28-03-2018 IPR000014 PAS domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SUPERFAMILY SSF47384 149 216 1.29E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 139 8.3E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS08090 fd9fb1226c106e6e3485da00cf10d36d 511 SMART SM00388 154 219 2.2E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03220 aa922b65c764aa18f102392ea19fc5e9 367 Pfam PF11306 Protein of unknown function (DUF3108) 122 362 6.9E-22 T 28-03-2018 IPR021457 Protein of unknown function DUF3108 hmeg3_RS03220 aa922b65c764aa18f102392ea19fc5e9 367 Gene3D G3DSA:2.50.20.10 113 367 1.0E-5 T 28-03-2018 hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 Pfam PF07729 FCD domain 97 221 3.7E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 SMART SM00345 14 73 1.5E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 Gene3D G3DSA:1.20.120.530 80 232 1.3E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 SMART SM00895 97 223 8.8E-20 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 SUPERFAMILY SSF48008 93 228 7.06E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 SUPERFAMILY SSF46785 3 77 7.97E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 Gene3D G3DSA:1.10.10.10 5 75 4.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.7E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03105 b62a9acbc027c962834a0ec657baa38c 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13710 5bcfc261c528bd5892136ffa5017d7b7 187 Gene3D G3DSA:3.90.79.10 5 183 2.3E-40 T 28-03-2018 hmeg3_RS13710 5bcfc261c528bd5892136ffa5017d7b7 187 SUPERFAMILY SSF55811 11 176 2.17E-47 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS13710 5bcfc261c528bd5892136ffa5017d7b7 187 Pfam PF00293 NUDIX domain 43 153 5.0E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS13710 5bcfc261c528bd5892136ffa5017d7b7 187 ProSitePatterns PS00893 Nudix box signature. 78 99 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 hmeg3_RS02535 80fba5a0e5aff465003a88b70ed8ab4f 187 Gene3D G3DSA:3.40.50.1580 19 85 2.5E-6 T 28-03-2018 hmeg3_RS02535 80fba5a0e5aff465003a88b70ed8ab4f 187 Gene3D G3DSA:3.40.50.1580 86 179 4.7E-13 T 28-03-2018 hmeg3_RS02535 80fba5a0e5aff465003a88b70ed8ab4f 187 SUPERFAMILY SSF53167 4 185 1.96E-29 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS02535 80fba5a0e5aff465003a88b70ed8ab4f 187 Pfam PF01048 Phosphorylase superfamily 112 170 8.8E-12 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS02535 80fba5a0e5aff465003a88b70ed8ab4f 187 Pfam PF01048 Phosphorylase superfamily 26 65 1.3E-6 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 SUPERFAMILY SSF54373 336 463 1.39E-32 T 28-03-2018 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 SUPERFAMILY SSF51905 36 338 8.55E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 SUPERFAMILY SSF51905 460 515 8.55E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 Pfam PF05199 GMC oxidoreductase 458 510 3.6E-13 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 Pfam PF00732 GMC oxidoreductase 40 317 4.5E-5 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 127 150 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 Gene3D G3DSA:3.30.410.10 179 275 8.8E-16 T 28-03-2018 hmeg3_RS21430 a3617ba44461f019f63a749c39618df0 520 Gene3D G3DSA:3.30.410.10 293 455 2.8E-54 T 28-03-2018 hmeg3_RS14400 6f240d2eaa5285d040d14510d2a429f4 476 SUPERFAMILY SSF51556 1 475 8.84E-160 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS14400 6f240d2eaa5285d040d14510d2a429f4 476 Pfam PF02614 Glucuronate isomerase 18 472 2.3E-72 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 hmeg3_RS14400 6f240d2eaa5285d040d14510d2a429f4 476 Gene3D G3DSA:3.20.20.140 2 98 6.8E-25 T 28-03-2018 hmeg3_RS14400 6f240d2eaa5285d040d14510d2a429f4 476 Hamap MF_00675 Uronate isomerase [uxaC]. 1 476 40.295 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 hmeg3_RS14400 6f240d2eaa5285d040d14510d2a429f4 476 Gene3D G3DSA:3.20.20.140 104 476 2.1E-125 T 28-03-2018 hmeg3_RS24100 32d860445b4a5d99cd9103762a73a278 90 SUPERFAMILY SSF117991 5 90 2.09E-27 T 28-03-2018 IPR027471 YbeD-like domain hmeg3_RS24100 32d860445b4a5d99cd9103762a73a278 90 Pfam PF04359 Protein of unknown function (DUF493) 7 90 1.3E-30 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 hmeg3_RS24100 32d860445b4a5d99cd9103762a73a278 90 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 2 90 22.553 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 hmeg3_RS24100 32d860445b4a5d99cd9103762a73a278 90 Gene3D G3DSA:3.30.70.260 6 90 1.5E-30 T 28-03-2018 hmeg3_RS24100 32d860445b4a5d99cd9103762a73a278 90 ProDom PD061650 JHP0447 HP0495 CJ0253 11 90 0.003 T 28-03-2018 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 179 4.1E-13 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 SUPERFAMILY SSF58104 231 512 6.54E-73 T 28-03-2018 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 Pfam PF00672 HAMP domain 211 258 1.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 Gene3D G3DSA:1.10.287.950 316 515 1.3E-47 T 28-03-2018 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 2.7E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 2.7E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 2.7E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 2.7E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 479 1.0E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 SMART SM00283 264 511 9.4E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 Gene3D G3DSA:1.10.287.950 208 315 2.6E-10 T 28-03-2018 hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 Gene3D G3DSA:1.20.120.30 26 185 1.7E-7 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS06155 a03374d215ff0f3d8328fc25b2a9d519 578 SMART SM00304 211 263 4.1E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 304 5.5E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 Pfam PF00005 ABC transporter 42 188 2.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 SMART SM00382 50 238 4.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 SUPERFAMILY SSF52540 5 260 3.63E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 324 7.7E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS09580 b3e8c43cd1355159fc0f6db8f69583d1 328 Gene3D G3DSA:3.40.50.300 1 328 5.0E-82 T 28-03-2018 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 SUPERFAMILY SSF52540 354 598 8.59E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 SUPERFAMILY SSF90123 20 336 2.09E-74 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 SMART SM00382 387 573 8.7E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 Pfam PF00005 ABC transporter 379 527 1.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 Gene3D G3DSA:1.20.1560.10 2 343 1.2E-70 T 28-03-2018 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 Pfam PF00664 ABC transporter transmembrane region 32 309 8.9E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 Gene3D G3DSA:3.40.50.300 348 601 3.0E-76 T 28-03-2018 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06940 345f060f517b56a4b326bfe1375ebd1b 601 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 14 598 1.2E-250 T 28-03-2018 IPR011918 ABC transporter, ATP-binding/permease protein hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 Gene3D G3DSA:3.40.50.150 96 288 7.8E-33 T 28-03-2018 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 199 205 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 Gene3D G3DSA:1.10.8.10 7 95 8.4E-12 T 28-03-2018 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 285 1.0E-67 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 SUPERFAMILY SSF53335 34 267 2.39E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 PIRSF PIRSF037167 1 297 3.1E-127 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 1 295 49.519 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 Pfam PF05175 Methyltransferase small domain 129 210 8.7E-18 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 hmeg3_RS09845 3718f125b3080420a99db6ff16e6f21d 297 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 7 289 1.5E-123 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 hmeg3_RS12760 426464338e2ee6f40deb33feb9693e60 82 Pfam PF11730 Protein of unknown function (DUF3297) 11 81 1.8E-38 T 28-03-2018 IPR021724 Protein of unknown function DUF3297 hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 Pfam PF03466 LysR substrate binding domain 93 292 7.4E-23 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 SUPERFAMILY SSF46785 5 89 9.12E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 SUPERFAMILY SSF53850 93 293 6.7E-26 T 28-03-2018 hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 Gene3D G3DSA:3.40.190.10 91 181 3.6E-11 T 28-03-2018 hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 Gene3D G3DSA:3.40.190.10 182 263 1.9E-10 T 28-03-2018 hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 5.6E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05310 5bbeabaa96f14009660a0cff7362f5f6 300 Gene3D G3DSA:1.10.10.10 2 88 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 SUPERFAMILY SSF52172 5 137 6.26E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 Gene3D G3DSA:3.40.50.2300 2 266 8.3E-37 T 28-03-2018 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 Pfam PF00196 Bacterial regulatory proteins, luxR family 277 332 5.0E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 ProSitePatterns PS00622 LuxR-type HTH domain signature. 292 319 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 SMART SM00448 9 122 4.7E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 Pfam PF00072 Response regulator receiver domain 11 122 1.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 SMART SM00421 275 332 8.0E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 Gene3D G3DSA:1.10.10.10 277 336 1.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 292 308 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 308 320 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 278 292 2.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01450 52843b472f170240a051fd95ff915700 347 SUPERFAMILY SSF46894 269 335 7.82E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 Pfam PF02311 AraC-like ligand binding domain 30 122 1.9E-7 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 257 2.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 226 241 2.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 Gene3D G3DSA:1.10.10.60 211 263 4.4E-11 T 28-03-2018 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 Gene3D G3DSA:1.10.10.60 154 210 2.6E-5 T 28-03-2018 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 Gene3D G3DSA:2.60.120.10 9 107 2.9E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 SUPERFAMILY SSF51182 22 184 2.54E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 253 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 SMART SM00342 174 257 2.8E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 SUPERFAMILY SSF46689 213 259 2.2E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS06270 b2ab03b7024195ba3a5eb743fd38899a 272 Pfam PF12833 Helix-turn-helix domain 181 257 1.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS09770 98aad498fd995123db1779932dd773e3 238 SUPERFAMILY SSF53067 3 102 2.42E-25 T 28-03-2018 hmeg3_RS09770 98aad498fd995123db1779932dd773e3 238 SUPERFAMILY SSF53067 110 212 6.47E-21 T 28-03-2018 hmeg3_RS09770 98aad498fd995123db1779932dd773e3 238 Gene3D G3DSA:3.30.420.40 138 226 0.058 T 28-03-2018 hmeg3_RS09770 98aad498fd995123db1779932dd773e3 238 Pfam PF00814 Glycoprotease family 33 166 7.6E-29 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS09770 98aad498fd995123db1779932dd773e3 238 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 214 6.5E-59 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 hmeg3_RS09770 98aad498fd995123db1779932dd773e3 238 Gene3D G3DSA:3.30.420.40 1 137 5.8E-38 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 Gene3D G3DSA:3.50.50.60 5 353 3.4E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 Gene3D G3DSA:3.40.30.20 427 496 6.3E-10 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 SUPERFAMILY SSF52833 389 495 2.91E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.1E-39 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 2.1E-39 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.1E-39 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 2.1E-39 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.1E-39 T 28-03-2018 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 SUPERFAMILY SSF51905 6 180 2.59E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 SUPERFAMILY SSF51905 270 353 2.59E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23990 2c9fb086a40030ecf975649be37b6e74 498 Pfam PF01494 FAD binding domain 6 345 2.1E-86 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 SUPERFAMILY SSF55347 155 317 8.93E-67 T 28-03-2018 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 5.6E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 5.6E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 5.6E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 5.6E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 5.6E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 1.6E-61 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 SMART SM00846 3 155 6.8E-97 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 1.7E-39 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 1.2E-129 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 Gene3D G3DSA:3.40.50.720 1 164 8.4E-76 T 28-03-2018 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 Gene3D G3DSA:3.30.360.10 165 318 3.1E-61 T 28-03-2018 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 SUPERFAMILY SSF51735 3 176 4.43E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 PIRSF PIRSF000149 1 337 4.3E-134 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS06795 54decdd37fa98f71bd873294ce632869 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SMART SM00073 2 99 8.2E-20 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SUPERFAMILY SSF55874 331 510 2.23E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SUPERFAMILY SSF47226 2 121 1.83E-26 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SUPERFAMILY SSF50341 506 636 3.14E-12 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Pfam PF01584 CheW-like domain 518 635 1.7E-8 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Gene3D G3DSA:3.30.565.10 331 514 2.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SUPERFAMILY SSF47384 258 329 1.88E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SMART SM00387 373 512 2.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SMART SM01231 257 328 5.6E-4 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Gene3D G3DSA:1.10.287.560 257 329 1.7E-7 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Gene3D G3DSA:2.30.30.40 568 634 0.38 T 28-03-2018 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 466 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 509 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 490 2.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 258 326 1.4E-8 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 SMART SM00260 504 635 1.8E-10 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 510 5.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Gene3D G3DSA:1.20.120.160 1 157 5.6E-28 T 28-03-2018 hmeg3_RS15275 79e0ae54e9a02103ac12231f0265d6f0 648 Pfam PF01627 Hpt domain 4 94 3.0E-14 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 Gene3D G3DSA:3.30.565.10 302 453 2.2E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 SMART SM00387 340 453 2.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 Gene3D G3DSA:1.10.287.130 222 291 6.5E-14 T 28-03-2018 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 SMART SM00388 232 295 8.4E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 SUPERFAMILY SSF158472 177 230 1.57E-6 T 28-03-2018 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 SUPERFAMILY SSF47384 217 295 4.51E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 Pfam PF00672 HAMP domain 177 228 6.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 SMART SM00304 176 231 2.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 SUPERFAMILY SSF55874 285 453 8.38E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 451 8.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10040 7c3cc07fa3a8657c39325a978cfe8a47 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 295 4.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10385 08f037dcbaeb1f0f66286056c0eaa754 119 SUPERFAMILY SSF159121 28 114 4.71E-20 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 hmeg3_RS10385 08f037dcbaeb1f0f66286056c0eaa754 119 Pfam PF06486 Protein of unknown function (DUF1093) 31 106 1.6E-15 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 hmeg3_RS10385 08f037dcbaeb1f0f66286056c0eaa754 119 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 13 113 6.4E-12 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 hmeg3_RS22520 47aec66562be1ee030ccf8d8bcf99695 312 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 5 310 2.4E-36 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 hmeg3_RS22520 47aec66562be1ee030ccf8d8bcf99695 312 Gene3D G3DSA:3.40.50.720 135 294 1.7E-24 T 28-03-2018 hmeg3_RS22520 47aec66562be1ee030ccf8d8bcf99695 312 Gene3D G3DSA:3.30.1780.10 1 134 2.3E-33 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 hmeg3_RS22520 47aec66562be1ee030ccf8d8bcf99695 312 PIRSF PIRSF001439 1 312 2.1E-53 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 hmeg3_RS22520 47aec66562be1ee030ccf8d8bcf99695 312 SUPERFAMILY SSF51735 1 310 3.25E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 8.0E-97 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 Gene3D G3DSA:3.40.50.2300 1 120 2.3E-34 T 28-03-2018 hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 Pfam PF00072 Response regulator receiver domain 3 111 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 SMART SM00448 1 111 1.9E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 Gene3D G3DSA:1.10.10.10 121 225 2.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 SUPERFAMILY SSF52172 1 177 9.05E-42 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 SMART SM00862 144 219 8.5E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS05655 1c4e58aed3ba0e64afccfba9e2bd3d9d 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 8.3E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 Gene3D G3DSA:1.20.120.160 146 231 1.7E-10 T 28-03-2018 hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 SUPERFAMILY SSF52172 10 143 4.84E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 Pfam PF00072 Response regulator receiver domain 12 126 7.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 SUPERFAMILY SSF47226 109 226 1.83E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 Gene3D G3DSA:3.40.50.2300 5 145 2.9E-36 T 28-03-2018 hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 Pfam PF01627 Hpt domain 151 221 2.4E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS15485 c9e4068791fb150fa9194d06e3f1a8f3 231 SMART SM00448 10 126 2.9E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 Gene3D G3DSA:3.90.180.10 3 180 3.8E-50 T 28-03-2018 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 SUPERFAMILY SSF50129 318 368 1.41E-12 T 28-03-2018 IPR011032 GroES-like hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 SUPERFAMILY SSF50129 1 184 1.48E-70 T 28-03-2018 IPR011032 GroES-like hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 Pfam PF00107 Zinc-binding dehydrogenase 197 319 4.6E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 368 8.3E-188 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 SUPERFAMILY SSF51735 160 333 8.37E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 153 9.6E-24 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 Gene3D G3DSA:3.40.50.10730 181 307 4.9E-32 T 28-03-2018 hmeg3_RS12860 7eb6081be7ec11691191ee50478dc1cf 368 SMART SM00829 12 366 0.0068 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 4.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 Gene3D G3DSA:3.40.50.2300 1 126 2.0E-35 T 28-03-2018 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 SMART SM00448 2 115 2.5E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 4.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 4.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 4.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 SMART SM00421 149 206 8.0E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 SUPERFAMILY SSF52172 1 131 6.4E-34 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 Gene3D G3DSA:1.10.10.10 127 214 2.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 SUPERFAMILY SSF46894 142 212 6.8E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 Pfam PF00072 Response regulator receiver domain 4 116 6.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS17380 d5c527d5f7e50c794877b6f009445a73 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 2.0E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 Gene3D G3DSA:3.50.50.60 3 162 1.5E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 SUPERFAMILY SSF51905 3 364 5.77E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 445 4.4E-37 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 Gene3D G3DSA:3.40.50.720 163 324 7.1E-39 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PIRSF PIRSF000350 1 441 7.9E-85 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.5E-26 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 3.5E-26 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 3.5E-26 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 3.5E-26 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 3.5E-26 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 440 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 1.7E-68 T 28-03-2018 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 Gene3D G3DSA:3.30.390.30 325 450 4.5E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 hmeg3_RS17330 05bf1d0c1079d20e1abe302fea8068d9 450 SUPERFAMILY SSF55424 334 446 3.09E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 hmeg3_RS08190 d4ea9403346c04f618cf126b4937721b 140 PIRSF PIRSF002889 1 140 2.3E-39 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 hmeg3_RS08190 d4ea9403346c04f618cf126b4937721b 140 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site hmeg3_RS08190 d4ea9403346c04f618cf126b4937721b 140 Pfam PF00460 Flagella basal body rod protein 9 39 7.1E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 hmeg3_RS08190 d4ea9403346c04f618cf126b4937721b 140 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 8 138 3.9E-33 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Pfam PF00873 AcrB/AcrD/AcrF family 4 1014 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82693 794 843 4.36E-12 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82693 667 707 4.36E-12 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82714 183 266 5.36E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Gene3D G3DSA:3.30.2090.10 709 795 3.0E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Gene3D G3DSA:3.30.70.1430 558 658 1.3E-12 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82714 709 792 2.62E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Gene3D G3DSA:3.30.2090.10 181 268 1.4E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82693 556 653 1.65E-14 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Gene3D G3DSA:1.20.1640.10 807 1028 8.6E-34 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82866 817 1012 7.59E-43 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82693 136 182 1.23E-19 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82693 268 324 1.23E-19 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82866 290 490 3.66E-46 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Gene3D G3DSA:1.20.1640.10 269 493 1.0E-45 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 SUPERFAMILY SSF82693 40 132 9.16E-23 T 28-03-2018 hmeg3_RS15965 9867c69fd0faf81d17c85951712e8ca9 1058 Gene3D G3DSA:3.30.70.1430 40 142 3.0E-23 T 28-03-2018 hmeg3_RS18040 e9a6373142886d80811416d7ae6400e1 397 SUPERFAMILY SSF56935 21 397 8.47E-71 T 28-03-2018 hmeg3_RS18040 e9a6373142886d80811416d7ae6400e1 397 PRINTS PR00184 Neisseria sp. porin signature 58 83 5.6E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18040 e9a6373142886d80811416d7ae6400e1 397 PRINTS PR00184 Neisseria sp. porin signature 342 366 5.6E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18040 e9a6373142886d80811416d7ae6400e1 397 Pfam PF13609 Gram-negative porin 7 369 6.8E-51 T 28-03-2018 hmeg3_RS18040 e9a6373142886d80811416d7ae6400e1 397 Gene3D G3DSA:2.40.160.10 9 397 4.9E-72 T 28-03-2018 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 35 791 4.4E-265 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Pfam PF07244 Surface antigen variable number repeat 358 432 1.8E-13 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Pfam PF07244 Surface antigen variable number repeat 277 355 1.2E-10 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Pfam PF07244 Surface antigen variable number repeat 187 274 3.0E-18 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Pfam PF07244 Surface antigen variable number repeat 36 102 3.1E-7 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Pfam PF07244 Surface antigen variable number repeat 104 183 2.0E-12 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 13 791 24.941 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Gene3D G3DSA:2.40.160.50 391 791 1.8E-80 T 28-03-2018 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 PIRSF PIRSF006076 4 791 7.6E-255 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Gene3D G3DSA:3.10.20.310 31 102 1.0E-12 T 28-03-2018 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Gene3D G3DSA:3.10.20.310 278 357 1.8E-13 T 28-03-2018 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Pfam PF01103 Surface antigen 459 791 1.1E-69 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Gene3D G3DSA:3.10.20.310 186 277 6.0E-23 T 28-03-2018 hmeg3_RS09975 8531cbf7a9ae1496c036df91047f0b5b 791 Gene3D G3DSA:3.10.20.310 103 185 7.1E-16 T 28-03-2018 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 ProSitePatterns PS00056 Ribosomal protein S17 signature. 61 73 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 Pfam PF00366 Ribosomal protein S17 15 81 7.6E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 10 80 7.0E-27 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 10 80 1.3E-36 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 Gene3D G3DSA:2.40.50.140 10 87 6.5E-31 T 28-03-2018 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 10 85 25.191 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 PRINTS PR00973 Ribosomal protein S17 family signature 29 52 1.1E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 PRINTS PR00973 Ribosomal protein S17 family signature 61 71 1.1E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 PRINTS PR00973 Ribosomal protein S17 family signature 71 78 1.1E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22815 54924a5874a0a4379fdccece0fa07bf2 90 SUPERFAMILY SSF50249 10 86 2.01E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 Gene3D G3DSA:3.40.47.10 5 146 5.8E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 Gene3D G3DSA:3.40.47.10 147 273 2.6E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 SUPERFAMILY SSF53901 279 400 1.99E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 SUPERFAMILY SSF53901 13 277 9.18E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 Gene3D G3DSA:3.40.47.10 274 398 1.8E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 15 399 8.5E-127 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 PIRSF PIRSF000429 8 401 1.5E-116 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 Pfam PF02803 Thiolase, C-terminal domain 279 399 1.6E-43 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS00605 ade1c4709052c95619503acea616f9f8 401 Pfam PF00108 Thiolase, N-terminal domain 13 271 7.9E-86 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS23415 55411899f3f99a891d5e557e5e51bac2 255 SUPERFAMILY SSF53639 12 219 3.92E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS23415 55411899f3f99a891d5e557e5e51bac2 255 SMART SM01007 17 202 3.9E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS23415 55411899f3f99a891d5e557e5e51bac2 255 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 17 202 7.5E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS23415 55411899f3f99a891d5e557e5e51bac2 255 Gene3D G3DSA:3.40.225.10 2 255 6.2E-78 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS07440 440f1d42596ca632bae73e7d7132096b 219 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 217 5.2E-75 T 28-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 hmeg3_RS07440 440f1d42596ca632bae73e7d7132096b 219 Gene3D G3DSA:3.40.50.150 16 218 1.5E-22 T 28-03-2018 hmeg3_RS07440 440f1d42596ca632bae73e7d7132096b 219 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 216 3.3E-84 T 28-03-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 hmeg3_RS07440 440f1d42596ca632bae73e7d7132096b 219 SUPERFAMILY SSF53335 1 217 7.85E-55 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS07440 440f1d42596ca632bae73e7d7132096b 219 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 217 38.839 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 hmeg3_RS07440 440f1d42596ca632bae73e7d7132096b 219 PIRSF PIRSF023956 1 219 2.8E-76 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 hmeg3_RS00705 a6770cd1a9c613ed0ca3703fab8ab4ac 488 Gene3D G3DSA:3.90.1300.10 1 487 3.5E-164 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00705 a6770cd1a9c613ed0ca3703fab8ab4ac 488 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 481 90.537 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00705 a6770cd1a9c613ed0ca3703fab8ab4ac 488 ProSitePatterns PS00571 Amidases signature. 147 178 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 hmeg3_RS00705 a6770cd1a9c613ed0ca3703fab8ab4ac 488 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 11 481 2.4E-175 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00705 a6770cd1a9c613ed0ca3703fab8ab4ac 488 Pfam PF01425 Amidase 23 470 8.5E-145 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00705 a6770cd1a9c613ed0ca3703fab8ab4ac 488 SUPERFAMILY SSF75304 3 487 1.44E-154 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS16660 7f6ed78cc4c87e6d64a316f78b49889c 256 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 12 245 2.6E-102 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 hmeg3_RS16660 7f6ed78cc4c87e6d64a316f78b49889c 256 Gene3D G3DSA:3.20.20.70 11 245 2.9E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS16660 7f6ed78cc4c87e6d64a316f78b49889c 256 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 13 246 1.1E-95 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 hmeg3_RS16660 7f6ed78cc4c87e6d64a316f78b49889c 256 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 250 121.543 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 hmeg3_RS16660 7f6ed78cc4c87e6d64a316f78b49889c 256 SUPERFAMILY SSF63892 11 248 1.7E-96 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Pfam PF00072 Response regulator receiver domain 4 115 3.4E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 SUPERFAMILY SSF52540 134 373 1.71E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 SUPERFAMILY SSF52172 1 175 4.41E-30 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Pfam PF00158 Sigma-54 interaction domain 135 298 1.1E-61 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 SMART SM00448 2 114 1.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Gene3D G3DSA:3.40.50.2300 1 127 4.6E-24 T 28-03-2018 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Gene3D G3DSA:1.10.10.60 391 445 1.6E-15 T 28-03-2018 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 345 354 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Pfam PF02954 Bacterial regulatory protein, Fis family 402 440 1.4E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 218 233 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 156 169 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Gene3D G3DSA:3.40.50.300 128 304 1.4E-25 T 28-03-2018 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 SUPERFAMILY SSF46689 345 443 1.2E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 407 424 1.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 424 444 1.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 Gene3D G3DSA:1.10.8.60 305 377 6.1E-19 T 28-03-2018 hmeg3_RS02300 7a9b81fb5581dc6a21b6ef11c76fc572 448 SMART SM00382 152 294 4.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 135 37.005 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 Gene3D G3DSA:3.90.1170.10 2 139 2.8E-47 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 PRINTS PR00060 Ribosomal protein L16 signature 59 88 4.2E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 PRINTS PR00060 Ribosomal protein L16 signature 25 37 4.2E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 PRINTS PR00060 Ribosomal protein L16 signature 43 54 4.2E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 PRINTS PR00060 Ribosomal protein L16 signature 89 118 4.2E-39 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 133 7.7E-48 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 60 71 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 SUPERFAMILY SSF54686 1 136 4.71E-51 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22825 015899162a8cf499653a1428414d10b6 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 3.1E-56 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07320 c95c60e5cc11d8f436bac813d9dd3e9c 466 SMART SM00267 274 450 8.9E-61 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07320 c95c60e5cc11d8f436bac813d9dd3e9c 466 Gene3D G3DSA:3.30.70.270 278 455 1.1E-49 T 28-03-2018 hmeg3_RS07320 c95c60e5cc11d8f436bac813d9dd3e9c 466 Pfam PF17158 Membrane-associated sensor, integral membrane domain 49 271 2.9E-17 T 28-03-2018 IPR033424 Membrane-associated sensor domain hmeg3_RS07320 c95c60e5cc11d8f436bac813d9dd3e9c 466 Pfam PF00990 Diguanylate cyclase, GGDEF domain 285 446 1.6E-48 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07320 c95c60e5cc11d8f436bac813d9dd3e9c 466 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 283 449 5.0E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07320 c95c60e5cc11d8f436bac813d9dd3e9c 466 SUPERFAMILY SSF55073 290 449 5.18E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 384 434 4.1E-15 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 379 961 4.4E-261 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:3.40.50.300 458 624 7.9E-38 T 28-03-2018 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 62 100 7.0E-15 T 28-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 959 17.354 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 SUPERFAMILY SSF52156 738 868 1.09E-37 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 SUPERFAMILY SSF50447 863 959 1.94E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:3.30.56.50 387 428 7.9E-11 T 28-03-2018 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:3.30.56.50 5 37 1.9E-8 T 28-03-2018 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Pfam PF11987 Translation-initiation factor 2 746 851 5.7E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:2.40.30.10 625 728 1.7E-14 T 28-03-2018 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:3.40.50.10050 759 840 4.7E-28 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:3.40.50.300 38 290 0.06 T 28-03-2018 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Gene3D G3DSA:2.40.30.10 862 960 5.0E-29 T 28-03-2018 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 ProSitePatterns PS01176 Initiation factor 2 signature. 912 934 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 Pfam PF00009 Elongation factor Tu GTP binding domain 466 621 1.4E-34 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 SUPERFAMILY SSF50447 634 716 2.91E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 SUPERFAMILY SSF46955 4 51 2.2E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 465 620 2.5E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS05590 bf1edd201f03e55e6cf1faf53ddd726f 961 SUPERFAMILY SSF52540 454 629 3.47E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 Gene3D G3DSA:1.20.120.380 263 346 2.5E-30 T 28-03-2018 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 SUPERFAMILY SSF56349 108 332 5.59E-70 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 113 326 2.0E-37 T 28-03-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 Gene3D G3DSA:3.30.66.10 45 110 8.7E-32 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 152 171 1.8E-8 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 196 212 1.8E-8 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 175 189 1.8E-8 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 261 275 1.8E-8 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 Gene3D G3DSA:3.90.15.10 111 257 3.5E-39 T 28-03-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 hmeg3_RS14205 8cd8ed890709ef8c19d3e4f109608b4b 381 SUPERFAMILY SSF55869 52 113 1.7E-21 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 Pfam PF01434 Peptidase family M41 387 593 1.4E-77 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 SUPERFAMILY SSF52540 151 396 1.31E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 325 2.6E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 Gene3D G3DSA:1.10.8.60 337 414 8.0E-26 T 28-03-2018 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 ProSitePatterns PS00674 AAA-protein family signature. 296 314 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 SUPERFAMILY SSF140990 407 602 1.44E-70 T 28-03-2018 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 Pfam PF06480 FtsH Extracellular 10 96 2.9E-8 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 SMART SM00382 189 328 1.6E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 615 36.768 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 594 6.8E-235 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 hmeg3_RS06545 c7300fd600069d8d001e05da9eb0e527 627 Gene3D G3DSA:3.40.50.300 136 336 3.6E-62 T 28-03-2018 hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 Gene3D G3DSA:2.60.40.10 422 533 1.6E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 Gene3D G3DSA:2.70.98.10 49 418 9.9E-165 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 SUPERFAMILY SSF81296 421 533 4.9E-24 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 SUPERFAMILY SSF74650 49 419 1.88E-157 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 49 528 2.1E-193 T 28-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 PIRSF PIRSF006281 5 533 1.8E-204 T 28-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D hmeg3_RS17725 a79e9ed602f896f15a5e1a4068b5ed92 533 Hamap MF_01069 Glucans biosynthesis protein G [mdoG]. 30 532 56.264 T 28-03-2018 IPR023704 Glucan biosynthesis protein G hmeg3_RS04390 91df0447818022023dcfe260236f05ad 171 SUPERFAMILY SSF55729 9 170 5.66E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS04390 91df0447818022023dcfe260236f05ad 171 Gene3D G3DSA:3.40.630.30 2 171 5.0E-35 T 28-03-2018 hmeg3_RS04390 91df0447818022023dcfe260236f05ad 171 Pfam PF00583 Acetyltransferase (GNAT) family 56 144 8.6E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS17345 ee557959b3256f2ad09ec9292b10b43c 344 SUPERFAMILY SSF53850 21 340 7.68E-78 T 28-03-2018 hmeg3_RS17345 ee557959b3256f2ad09ec9292b10b43c 344 Gene3D G3DSA:3.40.190.10 21 140 3.5E-4 T 28-03-2018 hmeg3_RS17345 ee557959b3256f2ad09ec9292b10b43c 344 Pfam PF13416 Bacterial extracellular solute-binding protein 43 306 9.3E-26 T 28-03-2018 hmeg3_RS17345 ee557959b3256f2ad09ec9292b10b43c 344 PIRSF PIRSF002825 4 344 6.0E-79 T 28-03-2018 IPR026045 Ferric binding protein hmeg3_RS17345 ee557959b3256f2ad09ec9292b10b43c 344 Gene3D G3DSA:3.40.190.10 141 303 3.3E-37 T 28-03-2018 hmeg3_RS13890 79df9631495978d4682104675db558f2 431 SMART SM01119 318 418 1.4E-34 T 28-03-2018 IPR026956 D-serine dehydratase-like domain hmeg3_RS13890 79df9631495978d4682104675db558f2 431 SUPERFAMILY SSF51419 56 292 4.25E-24 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS13890 79df9631495978d4682104675db558f2 431 Pfam PF14031 Putative serine dehydratase domain 318 416 3.7E-15 T 28-03-2018 IPR026956 D-serine dehydratase-like domain hmeg3_RS13890 79df9631495978d4682104675db558f2 431 Gene3D G3DSA:3.20.20.10 47 302 5.7E-32 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS13890 79df9631495978d4682104675db558f2 431 Pfam PF01168 Alanine racemase, N-terminal domain 56 240 5.0E-8 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 34 171 3.4E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 305 533 6.3E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 572 653 2.4E-11 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Gene3D G3DSA:3.90.1170.50 180 316 3.6E-41 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 5.8E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 SMART SM01008 203 281 1.1E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 204 254 4.4E-5 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Gene3D G3DSA:3.30.365.10 317 411 2.7E-29 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Gene3D G3DSA:3.30.365.10 412 568 2.2E-42 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 SUPERFAMILY SSF56003 17 236 2.65E-45 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 SUPERFAMILY SSF56003 305 705 3.01E-117 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 PIRSF PIRSF036389 1 706 2.4E-257 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Gene3D G3DSA:3.30.365.10 21 179 2.2E-43 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS22305 7a18c81bec7ca65b05f7a3848698cccd 706 Gene3D G3DSA:3.30.365.10 569 706 1.9E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15590 d815858c58fa32f0efff312eceb1c07f 333 Gene3D G3DSA:2.130.10.10 1 120 7.0E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS15590 d815858c58fa32f0efff312eceb1c07f 333 SUPERFAMILY SSF50974 58 329 5.49E-45 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 hmeg3_RS15590 d815858c58fa32f0efff312eceb1c07f 333 Gene3D G3DSA:2.130.10.10 121 332 8.6E-32 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS15590 d815858c58fa32f0efff312eceb1c07f 333 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 328 7.2E-91 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 Hamap MF_00163 Peptide deformylase [def]. 2 163 30.588 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 PIRSF PIRSF004749 1 169 3.5E-58 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 Gene3D G3DSA:3.90.45.10 1 169 3.9E-64 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 Pfam PF01327 Polypeptide deformylase 4 153 2.8E-53 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 SUPERFAMILY SSF56420 1 161 1.83E-63 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 PRINTS PR01576 Peptide deformylase signature 121 150 3.0E-37 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 PRINTS PR01576 Peptide deformylase signature 90 101 3.0E-37 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 PRINTS PR01576 Peptide deformylase signature 102 120 3.0E-37 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 PRINTS PR01576 Peptide deformylase signature 33 62 3.0E-37 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS00625 03f9da7af1caf69a09657f581b15df70 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 4.5E-56 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 Pfam PF12833 Helix-turn-helix domain 247 326 3.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 Gene3D G3DSA:3.40.50.880 2 241 1.8E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 Gene3D G3DSA:1.10.10.60 280 330 1.9E-11 T 28-03-2018 hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 Pfam PF01965 DJ-1/PfpI family 8 186 1.7E-23 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 SMART SM00342 241 324 1.7E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 Gene3D G3DSA:1.10.10.60 242 279 3.0E-6 T 28-03-2018 hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 SUPERFAMILY SSF46689 225 271 5.73E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 SUPERFAMILY SSF46689 277 327 3.45E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS10870 50ff325a7bf4574bbdfae10d69682113 330 SUPERFAMILY SSF52317 8 205 1.95E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 SUPERFAMILY SSF46689 199 249 6.05E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 Pfam PF12852 Cupin 2 182 8.3E-33 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 Gene3D G3DSA:1.10.10.60 254 305 3.2E-9 T 28-03-2018 hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 Gene3D G3DSA:1.10.10.60 194 253 5.8E-12 T 28-03-2018 hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 Gene3D G3DSA:2.60.120.280 5 183 2.3E-14 T 28-03-2018 hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 Pfam PF12833 Helix-turn-helix domain 221 296 2.0E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 SUPERFAMILY SSF51182 24 79 4.89E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 SMART SM00342 215 298 5.8E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS12730 c491c007f5a80b7a78ceddb9adb3d5b4 330 SUPERFAMILY SSF46689 251 301 2.11E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01690 2e83cc8aba01909bb2e5d9f38db65936 246 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 244 2.2E-51 T 28-03-2018 IPR018648 Protein of unknown function DUF2076 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 SUPERFAMILY SSF102114 32 324 2.35E-74 T 28-03-2018 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 31 374 3.3E-117 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 31 374 40.779 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 46 57 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 Gene3D G3DSA:3.20.20.70 27 374 3.2E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 Pfam PF04055 Radical SAM superfamily 44 213 1.2E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 Pfam PF13353 4Fe-4S single cluster domain 48 159 1.9E-9 T 28-03-2018 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 Pfam PF06463 Molybdenum Cofactor Synthesis C 221 347 8.3E-38 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 hmeg3_RS09090 2587a563bf5a13100455c30186329efc 374 SMART SM00729 40 254 2.0E-8 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 SMART SM00342 248 332 3.4E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 Pfam PF14525 AraC-binding-like domain 28 200 4.2E-29 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 Gene3D G3DSA:1.10.10.60 229 283 2.3E-8 T 28-03-2018 hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 Gene3D G3DSA:1.10.10.60 284 336 8.3E-7 T 28-03-2018 hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 SUPERFAMILY SSF46689 285 332 2.37E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 Pfam PF12833 Helix-turn-helix domain 254 332 1.0E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01270 871808f80db85e96926ce050cb0303d9 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 285 328 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 Gene3D G3DSA:3.30.420.150 115 295 2.6E-33 T 28-03-2018 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 Pfam PF02541 Ppx/GppA phosphatase family 18 297 1.2E-66 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 Gene3D G3DSA:3.30.420.40 1 114 2.3E-38 T 28-03-2018 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 SUPERFAMILY SSF53067 126 297 7.4E-42 T 28-03-2018 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 SUPERFAMILY SSF109604 303 482 9.57E-34 T 28-03-2018 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 PIRSF PIRSF001267 1 484 1.1E-155 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 hmeg3_RS09130 e330395ff23e3aebd75e11e019e996e5 485 SUPERFAMILY SSF53067 2 121 3.11E-33 T 28-03-2018 hmeg3_RS18395 8425a6c660f706461ca515a99fdeddbf 342 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 28 328 1.2E-72 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 hmeg3_RS18395 8425a6c660f706461ca515a99fdeddbf 342 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 10 341 39.068 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 hmeg3_RS18395 8425a6c660f706461ca515a99fdeddbf 342 SUPERFAMILY SSF52540 55 185 2.49E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18395 8425a6c660f706461ca515a99fdeddbf 342 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 22 336 1.7E-104 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 hmeg3_RS18395 8425a6c660f706461ca515a99fdeddbf 342 Gene3D G3DSA:3.40.50.300 55 184 4.9E-8 T 28-03-2018 hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 SUPERFAMILY SSF53383 119 479 7.69E-87 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 SMART SM00345 17 76 1.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 Gene3D G3DSA:3.90.1150.10 359 482 7.2E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 Gene3D G3DSA:1.10.10.10 6 84 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 Gene3D G3DSA:3.40.640.10 157 358 4.0E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 SUPERFAMILY SSF46785 10 80 1.01E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12270 a815263dd643e07eb8f7df2c513756ed 482 Pfam PF00155 Aminotransferase class I and II 148 436 5.8E-19 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 Gene3D G3DSA:3.30.70.980 83 174 3.7E-31 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 Pfam PF01709 Transcriptional regulator 5 237 4.4E-93 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 Gene3D G3DSA:3.30.70.980 175 241 1.5E-9 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.3E-92 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 35.241 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 SUPERFAMILY SSF75625 3 240 2.22E-94 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS18805 0c59c15294892b39222fb08f7757388c 241 Gene3D G3DSA:1.10.10.200 1 78 1.8E-31 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like hmeg3_RS13435 32b13405120ddc3372f11098cf7b10b5 210 Pfam PF01810 LysE type translocator 15 206 3.2E-36 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS13435 32b13405120ddc3372f11098cf7b10b5 210 PIRSF PIRSF006324 1 209 5.9E-61 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS03065 4000c6e5549e6eeba11ff3fd3116e3c7 350 Hamap MF_01962 Adenine deaminase. 16 332 85.781 T 28-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 hmeg3_RS03065 4000c6e5549e6eeba11ff3fd3116e3c7 350 Gene3D G3DSA:3.20.20.140 9 349 7.4E-82 T 28-03-2018 hmeg3_RS03065 4000c6e5549e6eeba11ff3fd3116e3c7 350 Pfam PF00962 Adenosine/AMP deaminase 20 341 1.6E-74 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 hmeg3_RS03065 4000c6e5549e6eeba11ff3fd3116e3c7 350 SUPERFAMILY SSF51556 15 346 3.4E-86 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS03065 4000c6e5549e6eeba11ff3fd3116e3c7 350 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 20 343 6.4E-112 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 SMART SM00344 20 129 1.1E-42 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 36 2.1E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 47 2.1E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 47 66 2.1E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 SUPERFAMILY SSF54909 83 165 3.62E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 Gene3D G3DSA:3.30.70.920 72 166 2.3E-21 T 28-03-2018 hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 Gene3D G3DSA:1.10.10.10 20 71 8.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 ProSitePatterns PS00519 AsnC-type HTH domain signature. 38 64 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 SUPERFAMILY SSF46785 19 78 4.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 Pfam PF01037 Lrp/AsnC ligand binding domain 86 160 3.5E-19 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS03850 8ef9aba9f4d5aef1f902e0a903c24407 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 20 67 1.3E-17 T 28-03-2018 hmeg3_RS20285 2b78e73ef44da8e737524887a1255610 231 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 3 223 1.1E-70 T 28-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 hmeg3_RS20285 2b78e73ef44da8e737524887a1255610 231 Gene3D G3DSA:1.10.8.60 158 224 3.2E-13 T 28-03-2018 hmeg3_RS20285 2b78e73ef44da8e737524887a1255610 231 Gene3D G3DSA:3.40.50.300 5 155 1.1E-11 T 28-03-2018 hmeg3_RS20285 2b78e73ef44da8e737524887a1255610 231 Pfam PF00308 Bacterial dnaA protein 14 202 1.9E-15 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA hmeg3_RS20285 2b78e73ef44da8e737524887a1255610 231 SUPERFAMILY SSF52540 13 203 4.08E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 SUPERFAMILY SSF53850 89 288 2.29E-29 T 28-03-2018 hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 Gene3D G3DSA:3.40.190.10 178 263 1.8E-16 T 28-03-2018 hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 Pfam PF03466 LysR substrate binding domain 88 288 2.3E-29 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 SUPERFAMILY SSF46785 1 85 4.89E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 Gene3D G3DSA:3.40.190.10 88 177 4.2E-17 T 28-03-2018 hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 Gene3D G3DSA:1.10.10.10 1 83 4.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11145 7a38401b180d1366e93b2df070d72b2b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.6E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 SUPERFAMILY SSF52402 260 520 2.05E-75 T 28-03-2018 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 PIRSF PIRSF006630 1 256 1.7E-79 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 PIRSF PIRSF006630 247 537 3.1E-117 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 Pfam PF00795 Carbon-nitrogen hydrolase 4 245 2.4E-32 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 TIGRFAM TIGR00552 nadE: NAD+ synthetase 271 515 1.7E-58 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 SUPERFAMILY SSF56317 3 248 1.44E-61 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 Pfam PF02540 NAD synthase 264 512 1.2E-71 T 28-03-2018 IPR022310 NAD/GMP synthase hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 Gene3D G3DSA:3.60.110.10 1 255 1.8E-60 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS16875 e8a98c1f973a1154445316d9967cb31b 537 Gene3D G3DSA:3.40.50.620 261 537 1.5E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS19395 a6180d966e58063046b6e76cae327a3e 431 Gene3D G3DSA:3.40.710.10 130 427 2.2E-47 T 28-03-2018 hmeg3_RS19395 a6180d966e58063046b6e76cae327a3e 431 Pfam PF00144 Beta-lactamase 137 409 3.4E-32 T 28-03-2018 IPR001466 Beta-lactamase-related hmeg3_RS19395 a6180d966e58063046b6e76cae327a3e 431 SUPERFAMILY SSF56601 101 413 2.96E-67 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 Gene3D G3DSA:1.10.10.10 171 258 8.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 SUPERFAMILY SSF51206 30 168 5.37E-28 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 SMART SM00100 37 157 6.4E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 SMART SM00419 193 241 3.7E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 Pfam PF00027 Cyclic nucleotide-binding domain 55 141 1.8E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 Pfam PF13545 Crp-like helix-turn-helix domain 174 245 6.1E-18 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 SUPERFAMILY SSF46785 172 253 3.62E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 Gene3D G3DSA:2.60.120.10 32 170 5.2E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 199 215 1.3E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11495 7dcd7735652310986b34ba7b55cf873d 265 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 215 230 1.3E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 Gene3D G3DSA:3.40.190.10 86 176 1.5E-14 T 28-03-2018 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 Pfam PF03466 LysR substrate binding domain 88 289 1.3E-44 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.1E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 SUPERFAMILY SSF46785 4 87 1.97E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 Gene3D G3DSA:1.10.10.10 3 83 5.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 SUPERFAMILY SSF53850 89 291 3.26E-45 T 28-03-2018 hmeg3_RS01430 d785eea5ebf5d1d976439c75917e4274 292 Gene3D G3DSA:3.40.190.10 177 261 7.5E-24 T 28-03-2018 hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 347 511 1.2E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 Pfam PF02743 Cache domain 54 243 1.7E-15 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 Pfam PF00990 Diguanylate cyclase, GGDEF domain 353 509 1.9E-48 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 SUPERFAMILY SSF103190 107 203 9.42E-5 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 Gene3D G3DSA:3.30.450.20 46 180 2.1E-18 T 28-03-2018 hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 Gene3D G3DSA:3.30.450.20 181 298 4.6E-12 T 28-03-2018 hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 Gene3D G3DSA:3.30.70.270 344 519 2.7E-52 T 28-03-2018 hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 SMART SM00267 340 513 2.0E-62 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12605 8d49961beaff1dd39fbfdc0f5db49995 524 SUPERFAMILY SSF55073 356 514 5.89E-45 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 4 508 7.9E-225 T 28-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 Gene3D G3DSA:3.30.420.40 246 511 1.7E-65 T 28-03-2018 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 452 7.0E-39 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 SUPERFAMILY SSF53067 4 250 6.74E-67 T 28-03-2018 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 248 1.3E-63 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 SUPERFAMILY SSF53067 251 494 2.12E-65 T 28-03-2018 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 PIRSF PIRSF000538 2 505 6.4E-141 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 Gene3D G3DSA:3.30.420.40 1 245 7.6E-67 T 28-03-2018 hmeg3_RS05105 8b1cc008bbba9ef5c98aec3e46fb3910 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 181 5.5E-16 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 SMART SM00304 213 265 6.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 Gene3D G3DSA:1.10.287.950 321 517 5.2E-50 T 28-03-2018 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 Gene3D G3DSA:1.10.287.950 82 320 8.1E-20 T 28-03-2018 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 SMART SM00283 266 513 1.6E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 479 9.8E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 SUPERFAMILY SSF58104 233 514 2.75E-78 T 28-03-2018 hmeg3_RS06325 8d7329a7f85dfdc69320255711f09925 588 Pfam PF00672 HAMP domain 214 260 4.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Gene3D G3DSA:3.40.50.300 392 639 6.1E-34 T 28-03-2018 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Gene3D G3DSA:3.40.50.300 146 282 5.9E-27 T 28-03-2018 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Gene3D G3DSA:3.40.50.300 2 145 1.3E-25 T 28-03-2018 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Pfam PF00580 UvrD/REP helicase N-terminal domain 9 272 5.9E-69 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 SUPERFAMILY SSF52540 7 654 7.17E-148 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Gene3D G3DSA:3.40.50.300 283 386 2.0E-26 T 28-03-2018 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Pfam PF13361 UvrD-like helicase C-terminal domain 278 633 2.3E-62 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS02675 aa84f104a6fed7261dda5c6e51af9640 693 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 7 682 37.869 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Pfam PF02780 Transketolase, C-terminal domain 484 600 4.3E-28 T 28-03-2018 IPR033248 Transketolase, C-terminal domain hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 SMART SM00861 308 472 1.5E-70 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 SUPERFAMILY SSF52518 306 493 1.45E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 SUPERFAMILY SSF52518 2 191 9.69E-82 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 SUPERFAMILY SSF52518 233 370 9.69E-82 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 SUPERFAMILY SSF52922 480 608 7.07E-35 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Gene3D G3DSA:3.40.50.970 1 287 3.1E-84 T 28-03-2018 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Gene3D G3DSA:3.40.50.970 288 477 6.3E-66 T 28-03-2018 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 3 606 4.0E-269 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 272 3.0E-124 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Pfam PF02779 Transketolase, pyrimidine binding domain 307 468 1.7E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Gene3D G3DSA:3.40.50.920 484 608 6.5E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 ProSitePatterns PS00802 Transketolase signature 2. 414 430 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS04815 57dd462917096ae69b509dd71874145a 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 609 46.827 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS19475 101195f1b20134fabf5697b2cdee8859 335 Pfam PF00589 Phage integrase family 164 316 8.8E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS19475 101195f1b20134fabf5697b2cdee8859 335 Gene3D G3DSA:1.10.150.130 55 164 5.1E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS19475 101195f1b20134fabf5697b2cdee8859 335 Gene3D G3DSA:1.10.443.10 165 326 5.2E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS19475 101195f1b20134fabf5697b2cdee8859 335 SUPERFAMILY SSF56349 61 322 7.65E-46 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS11780 63e2eaccf4fbdfc3d7ee3dc977729e19 491 Pfam PF02321 Outer membrane efflux protein 46 246 1.7E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS11780 63e2eaccf4fbdfc3d7ee3dc977729e19 491 Pfam PF02321 Outer membrane efflux protein 273 454 4.0E-14 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS11780 63e2eaccf4fbdfc3d7ee3dc977729e19 491 Gene3D G3DSA:1.20.1600.10 34 455 2.5E-43 T 28-03-2018 hmeg3_RS11780 63e2eaccf4fbdfc3d7ee3dc977729e19 491 SUPERFAMILY SSF56954 2 455 6.15E-57 T 28-03-2018 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 PIRSF PIRSF000194 7 167 8.4E-60 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 Gene3D G3DSA:3.40.430.10 6 167 1.4E-56 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 Pfam PF00186 Dihydrofolate reductase 11 166 8.0E-60 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 PRINTS PR00070 Dihydrofolate reductase signature 22 32 1.2E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 PRINTS PR00070 Dihydrofolate reductase signature 49 60 1.2E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 PRINTS PR00070 Dihydrofolate reductase signature 99 113 1.2E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 PRINTS PR00070 Dihydrofolate reductase signature 36 44 1.2E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 22 44 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 hmeg3_RS17730 1cfc6ddac0ea596d7d189b04127c47d9 167 SUPERFAMILY SSF53597 11 167 3.02E-58 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 hmeg3_RS13320 86fcd504c6e7e5101082a89b65408d56 295 SUPERFAMILY SSF53335 9 291 7.84E-91 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS13320 86fcd504c6e7e5101082a89b65408d56 295 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 282 39.986 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 hmeg3_RS13320 86fcd504c6e7e5101082a89b65408d56 295 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 285 1.5E-75 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 hmeg3_RS13320 86fcd504c6e7e5101082a89b65408d56 295 Gene3D G3DSA:3.40.50.150 1 295 2.9E-83 T 28-03-2018 hmeg3_RS19915 81d414b3b8551cac3a30404ce40b8293 342 Gene3D G3DSA:3.90.1200.10 102 340 1.0E-38 T 28-03-2018 hmeg3_RS19915 81d414b3b8551cac3a30404ce40b8293 342 SUPERFAMILY SSF56112 31 314 7.56E-59 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS19915 81d414b3b8551cac3a30404ce40b8293 342 Pfam PF01636 Phosphotransferase enzyme family 32 256 9.5E-35 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase hmeg3_RS19915 81d414b3b8551cac3a30404ce40b8293 342 Gene3D G3DSA:3.30.200.20 8 101 2.0E-29 T 28-03-2018 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 Gene3D G3DSA:3.40.190.10 123 215 7.4E-20 T 28-03-2018 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 Pfam PF01634 ATP phosphoribosyltransferase 54 209 5.4E-49 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 149 170 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 Gene3D G3DSA:3.40.190.10 1 122 9.8E-41 T 28-03-2018 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 214 56.347 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 SUPERFAMILY SSF53850 5 210 1.61E-65 T 28-03-2018 hmeg3_RS03475 d5c944a3a58d55664bf3481c306ef217 217 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 190 3.9E-59 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 hmeg3_RS22690 4ed92c014a63f99c469c5ca11b2f3a24 379 Gene3D G3DSA:1.20.1090.10 184 379 2.4E-50 T 28-03-2018 hmeg3_RS22690 4ed92c014a63f99c469c5ca11b2f3a24 379 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 hmeg3_RS22690 4ed92c014a63f99c469c5ca11b2f3a24 379 Gene3D G3DSA:3.40.50.1970 8 183 5.5E-44 T 28-03-2018 hmeg3_RS22690 4ed92c014a63f99c469c5ca11b2f3a24 379 SUPERFAMILY SSF56796 4 377 5.1E-109 T 28-03-2018 hmeg3_RS22690 4ed92c014a63f99c469c5ca11b2f3a24 379 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 370 4.0E-106 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 hmeg3_RS19955 07c42dc0a9aa14be294178d3ae9cf83a 173 Pfam PF00293 NUDIX domain 7 122 3.7E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS19955 07c42dc0a9aa14be294178d3ae9cf83a 173 SUPERFAMILY SSF55811 5 145 2.44E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS19955 07c42dc0a9aa14be294178d3ae9cf83a 173 Gene3D G3DSA:3.90.79.10 1 156 2.0E-23 T 28-03-2018 hmeg3_RS09010 5b1b5f9f0afa30b6e28145d76efa9aaa 218 SUPERFAMILY SSF48150 38 209 1.05E-38 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 hmeg3_RS09010 5b1b5f9f0afa30b6e28145d76efa9aaa 218 Gene3D G3DSA:1.10.1670.10 175 214 1.8E-13 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 hmeg3_RS09010 5b1b5f9f0afa30b6e28145d76efa9aaa 218 Gene3D G3DSA:1.10.340.30 19 174 1.5E-33 T 28-03-2018 hmeg3_RS09010 5b1b5f9f0afa30b6e28145d76efa9aaa 218 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 55 191 5.2E-12 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS09010 5b1b5f9f0afa30b6e28145d76efa9aaa 218 SMART SM00478 58 210 5.4E-12 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS23195 9ed32b2ed9321897d1353ebf6f9512f6 186 Gene3D G3DSA:1.20.120.20 93 184 6.1E-4 T 28-03-2018 hmeg3_RS23195 9ed32b2ed9321897d1353ebf6f9512f6 186 Pfam PF09361 Phasin protein 6 109 6.7E-24 T 28-03-2018 IPR018968 Phasin hmeg3_RS23195 9ed32b2ed9321897d1353ebf6f9512f6 186 TIGRFAM TIGR01841 phasin: phasin family protein 31 116 4.0E-21 T 28-03-2018 IPR010127 Phasin, subfamily 1 hmeg3_RS08700 e289b4e8ac7a7863264b6c15a5739def 121 SMART SM00448 3 116 7.3E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08700 e289b4e8ac7a7863264b6c15a5739def 121 Pfam PF00072 Response regulator receiver domain 5 116 1.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08700 e289b4e8ac7a7863264b6c15a5739def 121 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-37 T 28-03-2018 hmeg3_RS08700 e289b4e8ac7a7863264b6c15a5739def 121 SUPERFAMILY SSF52172 3 120 3.13E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS07820 f5d334de27c66be88b7e060f7d64a1f3 259 Pfam PF01522 Polysaccharide deacetylase 31 151 2.7E-19 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 hmeg3_RS07820 f5d334de27c66be88b7e060f7d64a1f3 259 SUPERFAMILY SSF88713 27 250 3.61E-30 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS07820 f5d334de27c66be88b7e060f7d64a1f3 259 Gene3D G3DSA:3.20.20.370 29 259 1.8E-31 T 28-03-2018 hmeg3_RS03785 1e3e5d6a5657b53b44a90c6d3be0a88b 245 Gene3D G3DSA:2.60.120.10 129 239 5.9E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS03785 1e3e5d6a5657b53b44a90c6d3be0a88b 245 Pfam PF05899 Protein of unknown function (DUF861) 167 233 2.3E-9 T 28-03-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 hmeg3_RS03785 1e3e5d6a5657b53b44a90c6d3be0a88b 245 SUPERFAMILY SSF51182 42 239 3.08E-14 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS03785 1e3e5d6a5657b53b44a90c6d3be0a88b 245 Gene3D G3DSA:2.60.120.10 16 128 4.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.0E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 9.0E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 9.0E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 9.0E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 9.0E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 Gene3D G3DSA:3.40.50.720 1 264 3.6E-55 T 28-03-2018 hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 SUPERFAMILY SSF51735 1 240 2.67E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11790 e2716ef60664c3b1a39eb897a899908b 268 Pfam PF00106 short chain dehydrogenase 3 185 5.0E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05430 ef24a77b1c0ad945bff07dfad7db3060 123 Gene3D G3DSA:3.40.50.2300 2 122 1.7E-33 T 28-03-2018 hmeg3_RS05430 ef24a77b1c0ad945bff07dfad7db3060 123 SMART SM00448 5 116 1.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05430 ef24a77b1c0ad945bff07dfad7db3060 123 SUPERFAMILY SSF52172 6 121 4.13E-33 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05430 ef24a77b1c0ad945bff07dfad7db3060 123 Pfam PF00072 Response regulator receiver domain 7 116 6.6E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS03130 fd614bb644080b1558498d075166340f 268 PIRSF PIRSF006241 1 260 7.1E-92 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 hmeg3_RS03130 fd614bb644080b1558498d075166340f 268 Pfam PF01261 Xylose isomerase-like TIM barrel 21 217 1.4E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain hmeg3_RS03130 fd614bb644080b1558498d075166340f 268 Gene3D G3DSA:3.20.20.150 1 260 1.5E-50 T 28-03-2018 hmeg3_RS03130 fd614bb644080b1558498d075166340f 268 SUPERFAMILY SSF51658 1 258 1.52E-78 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain hmeg3_RS05665 f3f788e8de9066cd2fa71dbdbe64a160 394 SUPERFAMILY SSF111369 67 305 1.44E-58 T 28-03-2018 hmeg3_RS05665 f3f788e8de9066cd2fa71dbdbe64a160 394 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 300 3.2E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS05665 f3f788e8de9066cd2fa71dbdbe64a160 394 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 51 380 3.0E-77 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS05665 f3f788e8de9066cd2fa71dbdbe64a160 394 Gene3D G3DSA:2.40.50.100 75 147 1.8E-18 T 28-03-2018 hmeg3_RS05665 f3f788e8de9066cd2fa71dbdbe64a160 394 Gene3D G3DSA:2.40.50.100 179 381 3.0E-6 T 28-03-2018 hmeg3_RS13885 07053a456db7c8d1676135bae768453c 293 SUPERFAMILY SSF53697 104 283 5.98E-34 T 28-03-2018 hmeg3_RS13885 07053a456db7c8d1676135bae768453c 293 Gene3D G3DSA:3.40.50.10490 99 284 2.5E-33 T 28-03-2018 hmeg3_RS13885 07053a456db7c8d1676135bae768453c 293 Gene3D G3DSA:1.10.10.10 1 83 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13885 07053a456db7c8d1676135bae768453c 293 Pfam PF01380 SIS domain 129 258 1.8E-16 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS13885 07053a456db7c8d1676135bae768453c 293 SUPERFAMILY SSF46689 5 78 1.45E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS13885 07053a456db7c8d1676135bae768453c 293 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 79 9.7E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 Pfam PF01553 Acyltransferase 443 569 6.6E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 Gene3D G3DSA:3.40.1130.10 419 624 2.0E-36 T 28-03-2018 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 Pfam PF07690 Major Facilitator Superfamily 19 323 6.5E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 Gene3D G3DSA:1.20.1250.20 2 211 5.5E-12 T 28-03-2018 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 SUPERFAMILY SSF103473 9 427 1.22E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 SMART SM00563 457 573 6.2E-28 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 SUPERFAMILY SSF69593 406 609 1.57E-31 T 28-03-2018 hmeg3_RS17275 ca85c538a8629ad9f68bdc6dab231152 628 Gene3D G3DSA:1.20.1250.20 213 418 1.2E-12 T 28-03-2018 hmeg3_RS05970 b8e4d0b79487aa7937bd7e8e06e2a246 196 Gene3D G3DSA:1.10.10.60 6 59 2.7E-14 T 28-03-2018 hmeg3_RS05970 b8e4d0b79487aa7937bd7e8e06e2a246 196 Gene3D G3DSA:1.10.357.10 60 194 5.5E-22 T 28-03-2018 hmeg3_RS05970 b8e4d0b79487aa7937bd7e8e06e2a246 196 SUPERFAMILY SSF46689 4 74 1.49E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05970 b8e4d0b79487aa7937bd7e8e06e2a246 196 Pfam PF16925 Bacterial transcriptional repressor C-terminal 103 184 8.1E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS05970 b8e4d0b79487aa7937bd7e8e06e2a246 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 53 2.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS05970 b8e4d0b79487aa7937bd7e8e06e2a246 196 SUPERFAMILY SSF48498 80 193 1.81E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 299 319 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 Pfam PF01180 Dihydroorotate dehydrogenase 51 343 5.4E-88 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 SUPERFAMILY SSF51395 6 343 5.66E-99 T 28-03-2018 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 7 342 5.1E-125 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 6 343 50.506 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 83 102 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 PIRSF PIRSF000164 20 344 7.7E-92 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 hmeg3_RS14325 26964df13d78d165a4fa5b4728f064a5 344 Gene3D G3DSA:3.20.20.70 2 344 6.2E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS11445 96aa80dc7312c516a5d48a7399cc954e 161 Gene3D G3DSA:1.10.287.70 7 156 4.7E-17 T 28-03-2018 hmeg3_RS11445 96aa80dc7312c516a5d48a7399cc954e 161 SUPERFAMILY SSF81324 5 144 2.22E-20 T 28-03-2018 hmeg3_RS11445 96aa80dc7312c516a5d48a7399cc954e 161 Pfam PF07885 Ion channel 37 110 4.2E-13 T 28-03-2018 IPR013099 Potassium channel domain hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 80 103 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Gene3D G3DSA:3.30.830.10 505 711 1.7E-28 T 28-03-2018 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Gene3D G3DSA:3.30.830.10 716 913 1.1E-34 T 28-03-2018 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 SUPERFAMILY SSF63411 744 911 1.91E-30 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 SUPERFAMILY SSF63411 49 264 1.06E-51 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Pfam PF05193 Peptidase M16 inactive domain 215 387 1.8E-20 T 28-03-2018 IPR007863 Peptidase M16, C-terminal hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Pfam PF05193 Peptidase M16 inactive domain 660 838 5.5E-30 T 28-03-2018 IPR007863 Peptidase M16, C-terminal hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 SUPERFAMILY SSF63411 277 459 1.31E-20 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Pfam PF00675 Insulinase (Peptidase family M16) 65 205 8.5E-19 T 28-03-2018 IPR011765 Peptidase M16, N-terminal hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 SUPERFAMILY SSF63411 506 707 8.62E-30 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Gene3D G3DSA:3.30.830.10 35 258 3.0E-55 T 28-03-2018 hmeg3_RS17785 e42ef95761c6398fcc49130682ae1653 913 Gene3D G3DSA:3.30.830.10 259 462 1.3E-17 T 28-03-2018 hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 Gene3D G3DSA:1.20.120.160 399 506 5.4E-17 T 28-03-2018 hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SUPERFAMILY SSF55785 348 396 6.02E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 Gene3D G3DSA:3.30.565.10 507 762 5.6E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 760 6.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SMART SM00304 207 260 9.8E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SMART SM00387 625 772 4.6E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 Pfam PF01627 Hpt domain 423 493 6.6E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SUPERFAMILY SSF158472 207 257 2.75E-5 T 28-03-2018 hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SUPERFAMILY SSF47226 422 504 5.36E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SMART SM00086 352 394 0.0016 T 28-03-2018 IPR001610 PAC motif hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 SUPERFAMILY SSF55874 587 749 8.32E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11380 acb5e3344f0f6c94509c71d57b9786a4 806 Gene3D G3DSA:3.30.450.20 249 398 5.2E-13 T 28-03-2018 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 Pfam PF02743 Cache domain 25 240 2.2E-16 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 SMART SM00304 350 402 9.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 SUPERFAMILY SSF55073 402 554 4.39E-40 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 Pfam PF00672 HAMP domain 350 398 2.7E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 Gene3D G3DSA:3.30.450.20 189 325 1.0E-13 T 28-03-2018 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 SUPERFAMILY SSF158472 350 398 3.01E-7 T 28-03-2018 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 396 554 2.5E-41 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 Gene3D G3DSA:3.30.70.270 387 557 8.8E-48 T 28-03-2018 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 SMART SM00267 386 558 4.5E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 Gene3D G3DSA:3.30.450.20 73 188 7.0E-17 T 28-03-2018 hmeg3_RS13375 5a559f96ccea608d9ba39a1568a77534 577 Pfam PF00990 Diguanylate cyclase, GGDEF domain 399 554 1.6E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 SUPERFAMILY SSF52540 277 487 7.9E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 Gene3D G3DSA:3.40.50.300 259 497 1.3E-22 T 28-03-2018 hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 Pfam PF00005 ABC transporter 278 434 1.4E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 Pfam PF00005 ABC transporter 24 168 1.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 Gene3D G3DSA:3.40.50.300 5 258 6.9E-60 T 28-03-2018 hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 SUPERFAMILY SSF52540 8 224 1.08E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03000 1ace0f2fc3832f1d6ef5a8d10752bd8f 520 SMART SM00382 32 224 1.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 TIGRFAM TIGR03247 glucar-dehydr: glucarate dehydratase 9 448 2.9E-260 T 28-03-2018 IPR017653 Glucarate dehydratase GO:0000287|GO:0008872|GO:0019394 KEGG: 00053+4.2.1.40|MetaCyc: PWY-6499 hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 SUPERFAMILY SSF54826 11 140 2.53E-33 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 SUPERFAMILY SSF51604 142 417 1.25E-80 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 SMART SM00922 188 288 1.7E-13 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 Gene3D G3DSA:3.30.390.10 2 143 2.4E-33 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 49 140 1.2E-4 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 Pfam PF13378 Enolase C-terminal domain-like 191 408 7.6E-36 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS24585 04824986a51c1398d8da1b860b49f24f 448 Gene3D G3DSA:3.20.20.120 144 415 2.5E-50 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS18300 502d4805c875bef240a710513eb8625b 320 Pfam PF02401 LytB protein 8 285 2.6E-94 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 hmeg3_RS18300 502d4805c875bef240a710513eb8625b 320 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 7 286 6.8E-103 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 hmeg3_RS18300 502d4805c875bef240a710513eb8625b 320 Gene3D G3DSA:3.40.50.2300 2 288 9.1E-4 T 28-03-2018 hmeg3_RS18300 502d4805c875bef240a710513eb8625b 320 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 6 288 38.25 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 Gene3D G3DSA:3.40.640.10 148 393 1.5E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 88 5.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 SMART SM00345 29 88 5.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 Gene3D G3DSA:1.10.10.10 20 90 2.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 3.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 3.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 Pfam PF00155 Aminotransferase class I and II 165 434 3.5E-22 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 Gene3D G3DSA:3.90.1150.10 394 500 3.2E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 SUPERFAMILY SSF53383 127 499 5.49E-87 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS12565 ff589097ad6b59827d19b169c07f0445 501 SUPERFAMILY SSF46785 20 92 6.36E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 SUPERFAMILY SSF46689 100 174 2.42E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 Gene3D G3DSA:1.10.10.60 132 174 4.2E-12 T 28-03-2018 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 158 178 4.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 141 158 4.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 SUPERFAMILY SSF52172 7 131 2.56E-25 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 Gene3D G3DSA:3.40.50.2300 1 131 1.4E-23 T 28-03-2018 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 SMART SM00448 5 117 3.3E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 Pfam PF02954 Bacterial regulatory protein, Fis family 136 174 5.9E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS11275 2271cedab8630e280250b0b25cf844bb 178 Pfam PF00072 Response regulator receiver domain 8 116 5.9E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 3.4E-121 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 Pfam PF00005 ABC transporter 18 164 2.3E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 Pfam PF12857 TOBE-like domain 288 345 1.6E-18 T 28-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 SUPERFAMILY SSF52540 3 247 1.69E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 SUPERFAMILY SSF50331 239 350 3.68E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 Gene3D G3DSA:3.40.50.300 1 241 1.1E-79 T 28-03-2018 hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 SMART SM00382 27 214 2.5E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14380 dade432860bb31c5351dd65458663648 366 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS02425 883efd7a0a73e1b0c0e1f6ac53523126 156 SUPERFAMILY SSF81573 63 121 2.22E-11 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain hmeg3_RS02425 883efd7a0a73e1b0c0e1f6ac53523126 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 8.8E-40 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 hmeg3_RS02425 883efd7a0a73e1b0c0e1f6ac53523126 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 4.2E-30 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 hmeg3_RS02425 883efd7a0a73e1b0c0e1f6ac53523126 156 Gene3D G3DSA:1.20.5.620 53 122 6.9E-12 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain hmeg3_RS02425 883efd7a0a73e1b0c0e1f6ac53523126 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 12.315 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 hmeg3_RS16490 a2b38031f11e1fc9e7067259268e4843 417 SUPERFAMILY SSF54631 27 147 1.54E-6 T 28-03-2018 hmeg3_RS16490 a2b38031f11e1fc9e7067259268e4843 417 SUPERFAMILY SSF81606 191 390 3.92E-6 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 hmeg3_RS16490 a2b38031f11e1fc9e7067259268e4843 417 Gene3D G3DSA:3.60.40.10 150 412 2.6E-20 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 hmeg3_RS16490 a2b38031f11e1fc9e7067259268e4843 417 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 206 410 4.6E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 hmeg3_RS16490 a2b38031f11e1fc9e7067259268e4843 417 Gene3D G3DSA:3.10.580.10 15 149 5.1E-5 T 28-03-2018 hmeg3_RS16490 a2b38031f11e1fc9e7067259268e4843 417 SMART SM00331 182 410 1.4E-7 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 hmeg3_RS05455 e2af1a1e659b987277bfcdc6c8860bae 185 Pfam PF12883 Protein of unknown function (DUF3828) 30 162 5.1E-9 T 28-03-2018 IPR024289 Domain of unknown function DUF3828 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 SUPERFAMILY SSF53732 3 465 6.41E-161 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 133 148 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 119 132 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 209 222 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 400 413 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 195 208 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 108 116 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 343 354 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 82 95 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 PRINTS PR00415 Aconitase family signature 286 300 7.3E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 Gene3D G3DSA:3.30.499.10 2 153 7.2E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 59.286 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 Gene3D G3DSA:3.40.1060.10 154 288 2.1E-42 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 Gene3D G3DSA:3.30.499.10 305 466 1.9E-50 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 2.1E-237 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 hmeg3_RS17260 74bf4e6491ab8716135c4a329cd911bc 466 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 1.6E-156 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS19725 b9921db4303e5fb9a755e751f9b17065 296 Pfam PF03547 Membrane transport protein 151 292 4.7E-10 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 SMART SM00283 264 511 1.3E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 SUPERFAMILY SSF58104 231 514 5.49E-75 T 28-03-2018 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 Gene3D G3DSA:1.10.287.950 323 515 1.5E-47 T 28-03-2018 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 Gene3D G3DSA:1.10.287.1060 230 322 0.015 T 28-03-2018 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 Pfam PF00672 HAMP domain 211 259 1.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 478 1.5E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 Gene3D G3DSA:1.20.120.30 24 185 1.2E-15 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 Pfam PF02203 Tar ligand binding domain homologue 5 171 2.1E-20 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS03935 00c2a2ffe57d2a5471c3c19fd58b2696 578 SMART SM00304 211 263 6.0E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02830 24cb488c3abb6149ad1c2e11af216cc3 244 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 197 2.6E-13 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS02830 24cb488c3abb6149ad1c2e11af216cc3 244 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 9 195 3.3E-47 T 28-03-2018 IPR010237 Pyrimidine 5-nucleotidase hmeg3_RS02830 24cb488c3abb6149ad1c2e11af216cc3 244 Gene3D G3DSA:3.40.50.1000 3 240 2.0E-23 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS02830 24cb488c3abb6149ad1c2e11af216cc3 244 SUPERFAMILY SSF56784 8 207 5.41E-30 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS02830 24cb488c3abb6149ad1c2e11af216cc3 244 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 197 6.7E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 Gene3D G3DSA:3.30.565.10 307 451 3.8E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 300 5.3E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 1.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 1.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.2E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 SMART SM00388 241 304 6.2E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 Gene3D G3DSA:1.10.287.130 231 300 4.3E-9 T 28-03-2018 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 SMART SM00304 187 240 5.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 SUPERFAMILY SSF55874 301 449 1.83E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 SMART SM00387 349 452 1.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 447 8.2E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS22255 05c77187becdf232aa47c83e432ff671 452 SUPERFAMILY SSF47384 224 301 6.67E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS14710 00394bc34210ed2214f9256e72a53d5e 467 Gene3D G3DSA:1.20.1600.10 32 454 1.1E-50 T 28-03-2018 hmeg3_RS14710 00394bc34210ed2214f9256e72a53d5e 467 Pfam PF02321 Outer membrane efflux protein 73 245 4.9E-16 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS14710 00394bc34210ed2214f9256e72a53d5e 467 Pfam PF02321 Outer membrane efflux protein 269 447 7.6E-9 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS14710 00394bc34210ed2214f9256e72a53d5e 467 SUPERFAMILY SSF56954 4 23 4.05E-60 T 28-03-2018 hmeg3_RS14710 00394bc34210ed2214f9256e72a53d5e 467 SUPERFAMILY SSF56954 69 449 4.05E-60 T 28-03-2018 hmeg3_RS01420 1cdbe84fff58a977724120b9b4f19ed2 247 SUPERFAMILY SSF47413 6 67 3.08E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS01420 1cdbe84fff58a977724120b9b4f19ed2 247 SMART SM00530 10 64 1.4E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS01420 1cdbe84fff58a977724120b9b4f19ed2 247 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 11 67 1.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS01420 1cdbe84fff58a977724120b9b4f19ed2 247 Gene3D G3DSA:1.10.260.40 8 85 1.8E-6 T 28-03-2018 hmeg3_RS02050 f89dda150502e11ecc5fb93ac4f9e62e 101 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 99 1.6E-26 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 499 9.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 518 9.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 462 9.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 412 518 5.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 SUPERFAMILY SSF55874 368 518 4.32E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 Pfam PF00512 His Kinase A (phospho-acceptor) domain 307 368 5.3E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 SUPERFAMILY SSF47384 288 368 1.26E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 SMART SM00388 301 369 3.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 SMART SM00387 410 521 3.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 Gene3D G3DSA:1.10.287.130 292 365 1.3E-12 T 28-03-2018 hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 Pfam PF17158 Membrane-associated sensor, integral membrane domain 52 278 3.8E-32 T 28-03-2018 IPR033424 Membrane-associated sensor domain hmeg3_RS03640 c156d97fa69914581819e00adf4bba1c 535 Gene3D G3DSA:3.30.565.10 374 519 3.8E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 SUPERFAMILY SSF52518 18 200 2.78E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 SMART SM00861 36 200 9.1E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 Gene3D G3DSA:3.40.50.970 7 211 7.7E-39 T 28-03-2018 hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 Pfam PF02780 Transketolase, C-terminal domain 212 333 4.4E-28 T 28-03-2018 IPR033248 Transketolase, C-terminal domain hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 Pfam PF02779 Transketolase, pyrimidine binding domain 41 199 1.4E-36 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 SUPERFAMILY SSF52922 206 343 2.75E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS21570 2b7c646b6d23e52a9a5d3950e1fc5614 343 Gene3D G3DSA:3.40.50.920 212 343 2.0E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS09445 58bda0a53cf9b8da36c6546b58483e61 98 Pfam PF07883 Cupin domain 37 95 4.7E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS09445 58bda0a53cf9b8da36c6546b58483e61 98 Gene3D G3DSA:2.60.120.10 1 98 8.2E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS09445 58bda0a53cf9b8da36c6546b58483e61 98 SUPERFAMILY SSF51182 2 97 2.35E-12 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 20 226 2.6E-79 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 250 312 7.1E-13 T 28-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 Gene3D G3DSA:2.30.130.10 248 316 4.7E-16 T 28-03-2018 IPR002478 PUA domain GO:0003723 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 SUPERFAMILY SSF55120 19 243 2.42E-80 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 41 188 1.3E-57 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 189 246 1.0E-12 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 SUPERFAMILY SSF88697 249 313 4.67E-8 T 28-03-2018 IPR015947 PUA-like domain hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 19 312 18.73 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05600 de1c18002c1257db7836eb8864a93dfd 317 Gene3D G3DSA:3.30.2350.10 18 239 1.5E-79 T 28-03-2018 hmeg3_RS23820 b6712510c9d008c966eaecfff56c5b67 565 Gene3D G3DSA:3.10.20.310 72 146 3.3E-8 T 28-03-2018 hmeg3_RS23820 b6712510c9d008c966eaecfff56c5b67 565 Gene3D G3DSA:2.40.160.50 174 565 1.0E-46 T 28-03-2018 hmeg3_RS23820 b6712510c9d008c966eaecfff56c5b67 565 Pfam PF17287 POTRA domain 147 201 3.0E-18 T 28-03-2018 IPR035251 ShlB, POTRA domain hmeg3_RS23820 b6712510c9d008c966eaecfff56c5b67 565 PIRSF PIRSF029745 1 565 2.7E-152 T 28-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 hmeg3_RS23820 b6712510c9d008c966eaecfff56c5b67 565 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 210 529 8.9E-105 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal hmeg3_RS23820 b6712510c9d008c966eaecfff56c5b67 565 Pfam PF08479 POTRA domain, ShlB-type 67 146 1.4E-20 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 PRINTS PR00061 Ribosomal protein L19 signature 36 65 2.0E-36 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 PRINTS PR00061 Ribosomal protein L19 signature 6 35 2.0E-36 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 PRINTS PR00061 Ribosomal protein L19 signature 90 115 2.0E-36 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 Pfam PF01245 Ribosomal protein L19 3 115 1.5E-47 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 115 4.4E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 116 30.488 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 SUPERFAMILY SSF50104 1 118 1.2E-45 T 28-03-2018 IPR008991 Translation protein SH3-like domain hmeg3_RS16025 8aed45708d707d857592b9e63a38ab64 128 PIRSF PIRSF002191 1 128 3.1E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM01079 71 263 7.5E-63 T 28-03-2018 IPR006189 CHASE domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM00086 428 470 4.8E-9 T 28-03-2018 IPR001610 PAC motif hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM00086 549 591 6.1E-6 T 28-03-2018 IPR001610 PAC motif hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SUPERFAMILY SSF55073 607 770 1.65E-45 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Gene3D G3DSA:3.30.450.20 484 598 3.0E-25 T 28-03-2018 hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SUPERFAMILY SSF141868 784 1031 1.44E-88 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Pfam PF00990 Diguanylate cyclase, GGDEF domain 602 763 1.7E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Pfam PF08447 PAS fold 379 457 2.4E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Gene3D G3DSA:3.20.20.450 772 1036 1.2E-100 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Gene3D G3DSA:3.30.450.20 332 483 2.7E-28 T 28-03-2018 hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SUPERFAMILY SSF55785 488 600 2.62E-29 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM00052 778 1024 1.6E-116 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Pfam PF13426 PAS domain 488 590 3.1E-18 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM00267 591 768 6.0E-58 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SUPERFAMILY SSF55785 345 468 2.44E-20 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Gene3D G3DSA:3.30.70.270 599 771 2.3E-56 T 28-03-2018 hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 485 597 3.0E-20 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 350 477 1.5E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Pfam PF00563 EAL domain 786 1019 8.1E-73 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 600 766 5.6E-43 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM00091 477 543 2.5E-4 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 SMART SM00091 354 422 0.12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18675 ae248574f883fb63c84d044ac1d67352 1037 Pfam PF03924 CHASE domain 75 261 7.0E-49 T 28-03-2018 IPR006189 CHASE domain hmeg3_RS00520 9911c7cbaefcdb9447b96e920d4c220f 415 SUPERFAMILY SSF103473 16 411 2.09E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00520 9911c7cbaefcdb9447b96e920d4c220f 415 Gene3D G3DSA:1.20.1250.20 23 227 1.8E-17 T 28-03-2018 hmeg3_RS00520 9911c7cbaefcdb9447b96e920d4c220f 415 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 38 404 2.9E-60 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB hmeg3_RS00520 9911c7cbaefcdb9447b96e920d4c220f 415 Gene3D G3DSA:1.20.1250.20 228 409 3.2E-17 T 28-03-2018 hmeg3_RS18830 41a95ebeb2566c7fead705d575352e78 245 SUPERFAMILY SSF81301 1 109 1.96E-34 T 28-03-2018 hmeg3_RS18830 41a95ebeb2566c7fead705d575352e78 245 Pfam PF02410 Ribosomal silencing factor during starvation 9 104 7.1E-24 T 28-03-2018 hmeg3_RS18830 41a95ebeb2566c7fead705d575352e78 245 Gene3D G3DSA:3.30.460.10 1 120 4.0E-31 T 28-03-2018 hmeg3_RS18830 41a95ebeb2566c7fead705d575352e78 245 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 22.982 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS hmeg3_RS18830 41a95ebeb2566c7fead705d575352e78 245 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.8E-32 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 Pfam PF00989 PAS fold 12 59 1.6E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 1.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 1.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 1.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 SUPERFAMILY SSF55874 202 355 1.57E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 Gene3D G3DSA:3.30.450.20 9 129 6.8E-7 T 28-03-2018 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 194 1.9E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 SMART SM00387 238 357 6.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 SMART SM00388 130 198 2.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 SUPERFAMILY SSF55785 11 95 1.92E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 356 8.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 Gene3D G3DSA:1.10.287.130 130 194 6.4E-15 T 28-03-2018 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 SUPERFAMILY SSF47384 120 194 6.08E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15460 ce7702578ed2a672e52a819f09da72c0 357 Gene3D G3DSA:3.30.565.10 199 357 7.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Pfam PF09382 RQC domain 415 526 5.4E-37 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Pfam PF00270 DEAD/DEAH box helicase 37 195 4.2E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SMART SM00956 420 523 2.1E-48 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SUPERFAMILY SSF52540 215 466 2.23E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 23 471 1.7E-159 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SMART SM00487 29 225 1.5E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SMART SM00341 543 619 2.1E-14 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Gene3D G3DSA:1.10.150.80 534 619 2.1E-26 T 28-03-2018 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Pfam PF00570 HRDC domain 547 613 5.5E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Pfam PF00271 Helicase conserved C-terminal domain 233 338 3.3E-17 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SMART SM00490 258 339 1.2E-25 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 22 615 3.0E-253 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SUPERFAMILY SSF52540 17 211 2.26E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Gene3D G3DSA:1.10.10.10 412 533 4.8E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Gene3D G3DSA:3.40.50.300 10 215 2.8E-35 T 28-03-2018 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Pfam PF16124 RecQ zinc-binding 351 413 1.3E-17 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 SUPERFAMILY SSF47819 540 615 8.94E-23 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 hmeg3_RS20870 413fc6458e457084664543fd84e65e61 620 Gene3D G3DSA:3.40.50.300 217 411 4.8E-43 T 28-03-2018 hmeg3_RS20355 2ede4e19b58527c80cf8e765d8f38d29 359 Gene3D G3DSA:1.10.287.950 89 194 8.8E-4 T 28-03-2018 hmeg3_RS20355 2ede4e19b58527c80cf8e765d8f38d29 359 Gene3D G3DSA:1.10.287.500 198 317 9.9E-12 T 28-03-2018 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 1.1E-157 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 Pfam PF00764 Arginosuccinate synthase 16 411 4.0E-57 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 444 69.386 T 28-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 Gene3D G3DSA:3.90.1260.10 179 374 4.5E-55 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 Gene3D G3DSA:1.10.287.400 378 437 1.5E-28 T 28-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 SUPERFAMILY SSF69864 190 443 8.24E-78 T 28-03-2018 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 Gene3D G3DSA:3.40.50.620 2 178 8.5E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 SUPERFAMILY SSF52402 7 186 1.16E-30 T 28-03-2018 hmeg3_RS06865 9788ac442054f420732e03e883b1afd1 446 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 SMART SM00345 17 75 2.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 SMART SM00895 85 208 1.1E-14 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 SUPERFAMILY SSF46785 10 79 4.46E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 Gene3D G3DSA:1.10.10.10 3 77 5.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 4.3E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 SUPERFAMILY SSF48008 80 213 3.92E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 Pfam PF07729 FCD domain 85 207 5.6E-22 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS20720 3bffe85ebdbab0e9f9656b9ee8130c35 217 Gene3D G3DSA:1.20.120.530 78 215 1.3E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 1.6E-11 T 28-03-2018 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.6E-11 T 28-03-2018 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.6E-11 T 28-03-2018 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 Gene3D G3DSA:3.50.50.60 5 129 2.4E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 Gene3D G3DSA:3.50.50.60 130 283 8.6E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 Pfam PF04324 BFD-like [2Fe-2S] binding domain 389 441 2.3E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 1.4E-5 T 28-03-2018 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.4E-5 T 28-03-2018 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 1.4E-5 T 28-03-2018 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 330 3.0E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 SUPERFAMILY SSF51905 7 342 2.79E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 PIRSF PIRSF037495 1 477 7.0E-138 T 28-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 hmeg3_RS24540 3967cc45b9ca2a09829be9371420243c 500 Gene3D G3DSA:3.50.50.60 284 373 2.5E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 Pfam PF01494 FAD binding domain 7 361 8.0E-76 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 SUPERFAMILY SSF51905 6 184 3.2E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 SUPERFAMILY SSF51905 283 389 3.2E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.2E-39 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 4.2E-39 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 4.2E-39 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 4.2E-39 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 347 4.2E-39 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 363 4.2E-39 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 Gene3D G3DSA:3.40.30.20 461 545 0.088 T 28-03-2018 hmeg3_RS20885 1146d7e5e984bedd1c5321d6581d3ca0 549 Gene3D G3DSA:3.50.50.60 4 408 3.5E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 SMART SM00535 18 146 4.4E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 29.206 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 219 1.7E-69 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 SMART SM00358 153 221 7.8E-15 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 SUPERFAMILY SSF69065 5 150 6.45E-48 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 Gene3D G3DSA:1.10.1520.10 4 144 4.5E-43 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 Pfam PF14622 Ribonuclease-III-like 16 138 7.6E-37 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 SUPERFAMILY SSF54768 106 220 9.9E-25 T 28-03-2018 hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 Pfam PF00035 Double-stranded RNA binding motif 153 218 3.7E-8 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain hmeg3_RS16680 c4bc5eb0932d1ca5e753e936d09b9688 358 Gene3D G3DSA:3.30.160.20 145 217 3.7E-15 T 28-03-2018 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 Pfam PF00108 Thiolase, N-terminal domain 5 211 3.7E-13 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 SUPERFAMILY SSF53901 5 121 6.61E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 SUPERFAMILY SSF53901 209 385 6.61E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 Gene3D G3DSA:3.40.47.10 243 403 4.9E-17 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 Gene3D G3DSA:3.40.47.10 6 242 5.5E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 PIRSF PIRSF000429 1 407 1.1E-56 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS20970 0f8b01e94d4d58bf4e7acdb573e2635a 416 Pfam PF02803 Thiolase, C-terminal domain 293 391 2.6E-9 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 SUPERFAMILY SSF89095 300 406 3.4E-32 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 147 161 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 Pfam PF02934 GatB/GatE catalytic domain 5 292 4.6E-114 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 Gene3D G3DSA:1.10.10.410 424 485 4.0E-22 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 SMART SM00845 331 484 7.0E-74 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 Pfam PF02637 GatB domain 332 484 4.2E-48 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 484 5.5E-172 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 485 38.255 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 hmeg3_RS00700 55517a0f270428935943307b8a47f307 486 SUPERFAMILY SSF55931 4 299 3.53E-120 T 28-03-2018 hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 Gene3D G3DSA:2.60.120.330 4 325 2.4E-100 T 28-03-2018 IPR027443 Isopenicillin N synthase-like hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 185 281 2.1E-22 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 PRINTS PR00682 Isopenicillin N synthase signature 36 53 6.4E-13 T 28-03-2018 hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 PRINTS PR00682 Isopenicillin N synthase signature 207 228 6.4E-13 T 28-03-2018 hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 PRINTS PR00682 Isopenicillin N synthase signature 243 269 6.4E-13 T 28-03-2018 hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 SUPERFAMILY SSF51197 12 324 8.24E-97 T 28-03-2018 hmeg3_RS21420 bb76ddbdb0e872769353e474ec9fd8f6 331 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 13 137 2.8E-31 T 28-03-2018 IPR026992 Non-haem dioxygenase N-terminal domain hmeg3_RS14450 6ad7bbf27e7dd80dcdd3e990b00db435 71 Pfam PF03459 TOBE domain 8 67 1.2E-15 T 28-03-2018 IPR005116 Transport-associated OB, type 1 hmeg3_RS14450 6ad7bbf27e7dd80dcdd3e990b00db435 71 Gene3D G3DSA:2.40.50.100 5 70 5.2E-17 T 28-03-2018 hmeg3_RS14450 6ad7bbf27e7dd80dcdd3e990b00db435 71 SUPERFAMILY SSF50331 6 69 4.37E-17 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS14450 6ad7bbf27e7dd80dcdd3e990b00db435 71 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 6 69 1.1E-17 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 hmeg3_RS02970 41fe76bf6ab62a856b18538779366b47 271 Pfam PF13614 AAA domain 3 164 5.9E-20 T 28-03-2018 IPR025669 AAA domain hmeg3_RS02970 41fe76bf6ab62a856b18538779366b47 271 Gene3D G3DSA:3.40.50.300 1 252 7.7E-51 T 28-03-2018 hmeg3_RS02970 41fe76bf6ab62a856b18538779366b47 271 PIRSF PIRSF003092 1 271 2.9E-90 T 28-03-2018 IPR025501 ATP binding protein MinD hmeg3_RS02970 41fe76bf6ab62a856b18538779366b47 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 2.7E-104 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 hmeg3_RS02970 41fe76bf6ab62a856b18538779366b47 271 SUPERFAMILY SSF52540 2 269 4.66E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 3.2E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 348 367 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 Gene3D G3DSA:1.10.540.10 5 128 8.4E-38 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 PIRSF PIRSF016578 10 394 6.4E-15 T 28-03-2018 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 Gene3D G3DSA:1.20.140.10 227 394 1.4E-51 T 28-03-2018 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 389 6.7E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 124 8.2E-37 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 SUPERFAMILY SSF56645 8 248 4.32E-85 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 SUPERFAMILY SSF47203 234 391 2.42E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS00610 1cf59354c0230be50071a04860a9c38a 394 Gene3D G3DSA:2.40.110.10 129 226 1.1E-40 T 28-03-2018 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 59 291 5.6E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 PRINTS PR00046 Major sigma-70 factor signature 240 252 5.6E-20 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 PRINTS PR00046 Major sigma-70 factor signature 111 119 5.6E-20 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 PRINTS PR00046 Major sigma-70 factor signature 87 100 5.6E-20 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 PRINTS PR00046 Major sigma-70 factor signature 277 288 5.6E-20 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 PRINTS PR00046 Major sigma-70 factor signature 262 277 5.6E-20 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 PIRSF PIRSF000770 15 295 4.8E-34 T 28-03-2018 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 SUPERFAMILY SSF88946 24 132 2.62E-40 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 11 294 50.851 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 Gene3D G3DSA:1.10.10.10 230 295 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 24 293 2.5E-122 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 262 288 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 Gene3D G3DSA:1.10.601.10 17 132 2.3E-35 T 28-03-2018 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 SUPERFAMILY SSF88659 197 293 5.05E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 Pfam PF04545 Sigma-70, region 4 236 289 6.5E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS03340 5b436b69171d44533513a8c86685691e 296 Pfam PF04542 Sigma-70 region 2 63 132 3.4E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS11985 ae05240cdf61bd84c0ad363ff7be4101 276 SUPERFAMILY SSF54593 17 127 2.38E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS11985 ae05240cdf61bd84c0ad363ff7be4101 276 Pfam PF13468 Glyoxalase-like domain 19 194 3.9E-28 T 28-03-2018 IPR025870 Glyoxalase-like domain hmeg3_RS11985 ae05240cdf61bd84c0ad363ff7be4101 276 Gene3D G3DSA:3.10.180.10 4 266 2.0E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 4.5E-158 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 SUPERFAMILY SSF56059 1 238 1.26E-82 T 28-03-2018 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 Gene3D G3DSA:3.30.470.20 96 239 1.5E-54 T 28-03-2018 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 PIRSF PIRSF001554 1 388 1.5E-154 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 Gene3D G3DSA:3.30.1490.20 21 95 3.6E-27 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 SUPERFAMILY SSF52210 239 385 3.53E-55 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.634 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 Pfam PF08442 ATP-grasp domain 2 202 3.3E-78 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 Pfam PF00549 CoA-ligase 262 382 1.5E-24 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS20150 f9bbe56d84f7cbae594ef969fafa32f1 388 Gene3D G3DSA:3.40.50.261 240 385 2.4E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 SMART SM00260 17 161 5.0E-15 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 PIRSF PIRSF002867 1 320 2.4E-100 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 SUPERFAMILY SSF52172 186 319 2.85E-24 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 Pfam PF01584 CheW-like domain 21 163 1.5E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 Pfam PF00072 Response regulator receiver domain 189 312 5.3E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 Gene3D G3DSA:2.40.50.180 45 108 5.2E-12 T 28-03-2018 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 SMART SM00448 187 312 2.5E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 Gene3D G3DSA:2.30.30.40 109 155 2.2E-6 T 28-03-2018 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 SUPERFAMILY SSF50341 17 163 6.15E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS11510 c2284e6ed176f123190d299fd1e80489 332 Gene3D G3DSA:3.40.50.2300 173 324 4.1E-25 T 28-03-2018 hmeg3_RS12700 5a6e39ee227589ecceea7e11da724b56 187 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 48 178 4.2E-30 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 Gene3D G3DSA:3.30.190.20 150 228 4.4E-20 T 28-03-2018 hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 SUPERFAMILY SSF56808 6 225 1.44E-79 T 28-03-2018 IPR023674 Ribosomal protein L1-like hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 2.3E-50 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 3.3E-102 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.492 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 PIRSF PIRSF002155 1 227 2.2E-75 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22920 11830fbf8890e5c3b7de0ac1a6d012a1 231 Gene3D G3DSA:3.40.50.790 68 149 1.2E-35 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 8.9E-5 T 28-03-2018 hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 8.9E-5 T 28-03-2018 hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 8.9E-5 T 28-03-2018 hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 SUPERFAMILY SSF103473 7 400 2.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 Pfam PF07690 Major Facilitator Superfamily 23 362 2.3E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 Gene3D G3DSA:1.20.1250.20 2 199 3.7E-32 T 28-03-2018 hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 Gene3D G3DSA:1.20.1250.20 206 408 5.3E-14 T 28-03-2018 hmeg3_RS00420 b245593c5233c793dc26321c1cb619c1 408 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 17 396 7.9E-102 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 hmeg3_RS18535 3bde3e557ed05603ca179edb85c964f2 442 SUPERFAMILY SSF51182 13 437 4.89E-171 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS18535 3bde3e557ed05603ca179edb85c964f2 442 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 13 436 71.192 T 28-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 hmeg3_RS18535 3bde3e557ed05603ca179edb85c964f2 442 Pfam PF04209 homogentisate 1,2-dioxygenase 13 434 1.3E-206 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 hmeg3_RS18535 3bde3e557ed05603ca179edb85c964f2 442 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 12 434 1.5E-200 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 hmeg3_RS18535 3bde3e557ed05603ca179edb85c964f2 442 Gene3D G3DSA:2.60.120.10 281 404 1.6E-52 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS18535 3bde3e557ed05603ca179edb85c964f2 442 Gene3D G3DSA:2.60.120.10 202 240 1.4E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS24505 ffcfc011e4c7f50f28737c774c0f9468 224 SUPERFAMILY SSF161098 18 212 1.44E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24505 ffcfc011e4c7f50f28737c774c0f9468 224 Gene3D G3DSA:1.10.3720.10 2 224 1.4E-36 T 28-03-2018 hmeg3_RS24505 ffcfc011e4c7f50f28737c774c0f9468 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 219 8.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24505 ffcfc011e4c7f50f28737c774c0f9468 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 120 9.2E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 SUPERFAMILY SSF55811 4 157 1.62E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 Gene3D G3DSA:3.90.79.10 1 164 8.7E-31 T 28-03-2018 hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.634 T 28-03-2018 IPR022927 RNA pyrophosphohydrolase RppH hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 PRINTS PR00502 NUDIX hydrolase family signature 47 62 9.6E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 PRINTS PR00502 NUDIX hydrolase family signature 33 47 9.6E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 hmeg3_RS21860 dc688eea171239c265fce2b343f44fb8 197 Pfam PF00293 NUDIX domain 7 136 2.5E-24 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 Gene3D G3DSA:1.10.10.10 1 84 5.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 SUPERFAMILY SSF53850 89 296 4.5E-37 T 28-03-2018 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.3E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 SUPERFAMILY SSF46785 3 83 1.61E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 Gene3D G3DSA:3.40.190.10 89 176 3.0E-21 T 28-03-2018 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 Gene3D G3DSA:3.40.190.10 177 268 1.6E-23 T 28-03-2018 hmeg3_RS04900 68e010055bd76aac6e7ad0ef5ec424e3 301 Pfam PF03466 LysR substrate binding domain 88 291 4.6E-40 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 Gene3D G3DSA:3.40.50.1000 449 581 1.0E-33 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 Gene3D G3DSA:3.40.1110.10 319 448 2.5E-21 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 Gene3D G3DSA:1.20.1110.10 56 318 3.7E-24 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 SUPERFAMILY SSF56784 302 322 1.85E-38 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 SUPERFAMILY SSF56784 393 572 1.85E-38 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 SUPERFAMILY SSF81665 21 96 8.89E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 SUPERFAMILY SSF81665 201 298 8.89E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 147 161 3.6E-24 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 468 478 3.6E-24 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 544 556 3.6E-24 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 3.6E-24 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 521 540 3.6E-24 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 306 312 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 1 685 41.312 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 373 609 1.6E-42 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 65 340 1.4E-32 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 535 1.4E-32 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 Pfam PF00122 E1-E2 ATPase 107 283 1.3E-31 T 28-03-2018 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 SUPERFAMILY SSF81653 107 200 2.22E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 hmeg3_RS06050 88b96306c877afa0b04136b789b7e2e6 687 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 2 681 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 hmeg3_RS04135 6d5ffc174a015ba5c0b42f83499cdfc6 204 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 161 183 2.6E-5 T 28-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 hmeg3_RS04135 6d5ffc174a015ba5c0b42f83499cdfc6 204 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 10 33 2.6E-5 T 28-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 hmeg3_RS04135 6d5ffc174a015ba5c0b42f83499cdfc6 204 SUPERFAMILY SSF81342 3 197 1.57E-35 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 hmeg3_RS04135 6d5ffc174a015ba5c0b42f83499cdfc6 204 Pfam PF01292 Prokaryotic cytochrome b561 8 195 2.2E-24 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 hmeg3_RS04135 6d5ffc174a015ba5c0b42f83499cdfc6 204 Gene3D G3DSA:1.20.950.20 1 204 8.2E-38 T 28-03-2018 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 94 3.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 SUPERFAMILY SSF46785 26 102 2.65E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 SUPERFAMILY SSF53383 89 500 8.93E-87 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 SMART SM00345 35 94 8.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 Gene3D G3DSA:3.90.1150.10 402 501 7.2E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 1.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 1.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 Pfam PF00155 Aminotransferase class I and II 163 467 7.3E-23 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 Gene3D G3DSA:1.10.10.10 12 96 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12000 903e78077e4cbded947ab7c216699760 518 Gene3D G3DSA:3.40.640.10 158 401 2.6E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS20955 dbd0e8d2649a3b44fa7d6c8bff00bd2b 446 Pfam PF00501 AMP-binding enzyme 93 299 1.1E-14 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS20955 dbd0e8d2649a3b44fa7d6c8bff00bd2b 446 Pfam PF14535 AMP-binding enzyme C-terminal domain 350 443 2.8E-17 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal hmeg3_RS20955 dbd0e8d2649a3b44fa7d6c8bff00bd2b 446 SUPERFAMILY SSF56801 44 444 1.44E-48 T 28-03-2018 hmeg3_RS20955 dbd0e8d2649a3b44fa7d6c8bff00bd2b 446 Gene3D G3DSA:3.30.300.30 340 445 2.3E-8 T 28-03-2018 hmeg3_RS20955 dbd0e8d2649a3b44fa7d6c8bff00bd2b 446 Gene3D G3DSA:3.40.50.980 96 273 3.8E-22 T 28-03-2018 hmeg3_RS15190 1e2003ba73c5e436f46fecebe8be46c3 159 Gene3D G3DSA:3.40.630.30 2 159 1.6E-24 T 28-03-2018 hmeg3_RS15190 1e2003ba73c5e436f46fecebe8be46c3 159 Pfam PF00583 Acetyltransferase (GNAT) family 39 132 6.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS15190 1e2003ba73c5e436f46fecebe8be46c3 159 SUPERFAMILY SSF55729 3 157 4.22E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS22585 00769bcf27ba5c9b001dedb032a8afb6 141 SUPERFAMILY SSF52821 9 134 3.67E-30 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS22585 00769bcf27ba5c9b001dedb032a8afb6 141 Pfam PF00581 Rhodanese-like domain 37 126 5.1E-16 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS22585 00769bcf27ba5c9b001dedb032a8afb6 141 Gene3D G3DSA:3.40.250.10 25 138 5.9E-27 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS22585 00769bcf27ba5c9b001dedb032a8afb6 141 SMART SM00450 33 130 1.6E-24 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS00335 89064cc3aeefb66c2928dc89c6253923 279 SUPERFAMILY SSF47240 12 187 5.88E-35 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS00335 89064cc3aeefb66c2928dc89c6253923 279 Gene3D G3DSA:1.10.620.20 2 258 1.4E-30 T 28-03-2018 hmeg3_RS04275 03bc2d2d5651fc46d969abf56d636340 241 Pfam PF01797 Transposase IS200 like 12 122 7.1E-16 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 hmeg3_RS04275 03bc2d2d5651fc46d969abf56d636340 241 Gene3D G3DSA:3.30.70.1290 3 130 2.6E-28 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 hmeg3_RS04275 03bc2d2d5651fc46d969abf56d636340 241 SUPERFAMILY SSF143422 3 127 1.96E-31 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 hmeg3_RS04275 03bc2d2d5651fc46d969abf56d636340 241 SMART SM01321 9 124 1.5E-42 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 SMART SM01086 771 860 2.5E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Gene3D G3DSA:3.40.50.300 157 342 3.0E-25 T 28-03-2018 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 SUPERFAMILY SSF81923 4 140 1.47E-39 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 SUPERFAMILY SSF52540 160 550 3.18E-99 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 337 1.2E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 771 851 3.6E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Gene3D G3DSA:1.10.8.60 343 551 8.7E-43 T 28-03-2018 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Gene3D G3DSA:3.40.50.300 552 784 2.8E-50 T 28-03-2018 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Pfam PF07724 AAA domain (Cdc48 subfamily) 603 765 1.1E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 SMART SM00382 603 758 1.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 SMART SM00382 198 343 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 860 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 5.3E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 1.6E-9 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Gene3D G3DSA:1.10.8.60 785 863 2.1E-21 T 28-03-2018 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 SUPERFAMILY SSF52540 552 855 9.24E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 Gene3D G3DSA:1.10.1780.10 2 154 7.6E-34 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 2.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 2.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 2.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 2.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS13380 236067e810dc6de36eed19c892bd3ed1 863 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 748 767 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 772 781 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 839 847 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 685 692 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 816 832 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 785 796 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 712 721 1.3E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 Gene3D G3DSA:3.40.50.360 378 565 6.3E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 Gene3D G3DSA:2.40.30.10 566 731 1.4E-18 T 28-03-2018 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 SUPERFAMILY SSF63380 572 738 6.29E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00369 Flavodoxin signature 416 429 1.9E-10 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00369 Flavodoxin signature 496 506 1.9E-10 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00369 Flavodoxin signature 464 475 1.9E-10 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 PRINTS PR00369 Flavodoxin signature 520 539 1.9E-10 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 SUPERFAMILY SSF52218 415 555 2.51E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 Pfam PF00175 Oxidoreductase NAD-binding domain 749 853 6.6E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 Gene3D G3DSA:3.40.50.80 735 879 9.1E-23 T 28-03-2018 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 SUPERFAMILY SSF52343 742 880 2.62E-33 T 28-03-2018 hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 Pfam PF03929 PepSY-associated TM region 7 382 3.0E-66 T 28-03-2018 IPR005625 PepSY-associated TM protein hmeg3_RS18570 60693e9a7d7d6e34db47e0674aace820 880 Pfam PF00258 Flavodoxin 418 541 9.5E-28 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.9E-26 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 SUPERFAMILY SSF55307 201 316 5.26E-37 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 12 319 1.8E-110 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 Gene3D G3DSA:3.30.1330.20 212 321 2.8E-38 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 SMART SM00865 204 322 1.4E-44 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 171 2.3E-34 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 ProSitePatterns PS01135 FtsZ protein signature 2. 95 116 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 PRINTS PR00423 Cell division protein FtsZ signature 186 208 3.9E-44 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 PRINTS PR00423 Cell division protein FtsZ signature 209 230 3.9E-44 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 PRINTS PR00423 Cell division protein FtsZ signature 96 116 3.9E-44 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 PRINTS PR00423 Cell division protein FtsZ signature 124 145 3.9E-44 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 SMART SM00864 14 202 2.8E-99 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 SUPERFAMILY SSF52490 15 205 1.16E-59 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 340 33.748 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 hmeg3_RS21985 63959974c1c90869ee3272003748c93f 398 Gene3D G3DSA:3.40.50.1440 7 211 9.3E-37 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 hmeg3_RS21020 519bc9857cb5b40b3517ea099cda7144 218 SUPERFAMILY SSF161098 9 201 2.88E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21020 519bc9857cb5b40b3517ea099cda7144 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 214 1.3E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21020 519bc9857cb5b40b3517ea099cda7144 218 Gene3D G3DSA:1.10.3720.10 1 217 5.0E-42 T 28-03-2018 hmeg3_RS02580 88da3e592a49ec7fee0efc2c7684ed49 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 8.0E-25 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS02580 88da3e592a49ec7fee0efc2c7684ed49 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.997 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS02580 88da3e592a49ec7fee0efc2c7684ed49 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS02580 88da3e592a49ec7fee0efc2c7684ed49 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 32 2.0E-9 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS02580 88da3e592a49ec7fee0efc2c7684ed49 45 Pfam PF00468 Ribosomal protein L34 1 44 4.7E-24 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 Gene3D G3DSA:2.40.170.20 205 745 3.4E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 Pfam PF07715 TonB-dependent Receptor Plug Domain 92 186 2.2E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 91 745 1.5E-106 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 SUPERFAMILY SSF56935 47 745 4.27E-103 T 28-03-2018 hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 728 745 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 Pfam PF00593 TonB dependent receptor 282 743 4.9E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10340 c1197cd85645f0a1096dfd11b9e6599f 745 Gene3D G3DSA:2.170.130.10 41 204 6.5E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS08310 d0ccea371dc2d89f23dab197665f92b0 232 PRINTS PR01003 Flagellar assembly protein FliH signature 185 201 4.2E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 hmeg3_RS08310 d0ccea371dc2d89f23dab197665f92b0 232 PRINTS PR01003 Flagellar assembly protein FliH signature 58 80 4.2E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 hmeg3_RS08310 d0ccea371dc2d89f23dab197665f92b0 232 PRINTS PR01003 Flagellar assembly protein FliH signature 202 227 4.2E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 hmeg3_RS08310 d0ccea371dc2d89f23dab197665f92b0 232 PRINTS PR01003 Flagellar assembly protein FliH signature 81 99 4.2E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 hmeg3_RS08310 d0ccea371dc2d89f23dab197665f92b0 232 Pfam PF02108 Flagellar assembly protein FliH 94 220 4.2E-37 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE hmeg3_RS23645 693725953b794c3fd478cfa3aef2dd24 181 Gene3D G3DSA:4.10.1070.10 55 164 3.6E-5 T 28-03-2018 hmeg3_RS23645 693725953b794c3fd478cfa3aef2dd24 181 Gene3D G3DSA:3.90.1340.10 2 54 9.4E-21 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS23645 693725953b794c3fd478cfa3aef2dd24 181 SUPERFAMILY SSF88874 2 175 1.44E-45 T 28-03-2018 hmeg3_RS23645 693725953b794c3fd478cfa3aef2dd24 181 Pfam PF07484 Phage Tail Collar Domain 7 63 4.9E-25 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS05440 6a7af2063ac645e2dcd65c1b21f87a38 436 Pfam PF13487 HD domain 236 298 5.2E-12 T 28-03-2018 hmeg3_RS05440 6a7af2063ac645e2dcd65c1b21f87a38 436 Gene3D G3DSA:1.10.3210.10 130 347 3.5E-40 T 28-03-2018 hmeg3_RS05440 6a7af2063ac645e2dcd65c1b21f87a38 436 SUPERFAMILY SSF109604 180 344 5.8E-30 T 28-03-2018 hmeg3_RS05440 6a7af2063ac645e2dcd65c1b21f87a38 436 Pfam PF11871 Domain of unknown function (DUF3391) 4 153 3.9E-32 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 hmeg3_RS05440 6a7af2063ac645e2dcd65c1b21f87a38 436 SMART SM00471 181 317 6.9E-9 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS18895 c66692152f9547722c033b0dad0bc4d2 185 SUPERFAMILY SSF47413 6 73 1.21E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS18895 c66692152f9547722c033b0dad0bc4d2 185 Pfam PF01381 Helix-turn-helix 13 64 3.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS18895 c66692152f9547722c033b0dad0bc4d2 185 Gene3D G3DSA:2.60.120.10 76 184 1.5E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS18895 c66692152f9547722c033b0dad0bc4d2 185 SMART SM00530 12 67 3.7E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS18895 c66692152f9547722c033b0dad0bc4d2 185 SUPERFAMILY SSF51182 53 181 1.07E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS18895 c66692152f9547722c033b0dad0bc4d2 185 Gene3D G3DSA:1.10.260.40 1 75 2.6E-16 T 28-03-2018 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 244 355 2.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 SMART SM00387 243 357 1.3E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 Gene3D G3DSA:3.30.565.10 163 356 2.3E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 SUPERFAMILY SSF55874 188 357 1.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 335 5.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 354 5.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 316 5.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 302 5.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 Gene3D G3DSA:3.30.450.20 53 162 4.8E-5 T 28-03-2018 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 SMART SM00388 131 201 1.1E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 SUPERFAMILY SSF47384 119 198 6.67E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05420 61afa3b5bafc372fe0f8eb429545b2a5 363 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 198 7.1E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 242 4.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 SUPERFAMILY SSF52172 11 139 7.54E-40 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 SMART SM00862 166 242 7.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 Pfam PF00072 Response regulator receiver domain 16 125 2.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 SUPERFAMILY SSF46894 143 243 7.37E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 Gene3D G3DSA:1.10.10.10 137 249 2.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 Gene3D G3DSA:3.40.50.2300 6 136 2.9E-38 T 28-03-2018 hmeg3_RS06470 49689d7d19c5d88a411fd7e41432b96b 251 SMART SM00448 14 125 6.2E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 SMART SM01049 36 130 8.0E-32 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 Gene3D G3DSA:1.10.287.950 224 316 7.9E-6 T 28-03-2018 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 481 1.9E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 Gene3D G3DSA:1.10.287.950 317 517 7.1E-46 T 28-03-2018 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 SUPERFAMILY SSF58104 248 515 7.32E-60 T 28-03-2018 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 Pfam PF17200 Single Cache domain 2 40 189 1.6E-35 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 Gene3D G3DSA:3.30.450.20 29 193 2.0E-40 T 28-03-2018 hmeg3_RS01875 17ae0541655c331cf998c04ec127b581 517 SMART SM00283 267 514 3.4E-66 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01555 7dbd4f8e91f17199dce8605210acf04c 448 Gene3D G3DSA:1.20.1250.20 214 431 8.5E-22 T 28-03-2018 hmeg3_RS01555 7dbd4f8e91f17199dce8605210acf04c 448 Gene3D G3DSA:1.20.1250.20 2 213 8.4E-25 T 28-03-2018 hmeg3_RS01555 7dbd4f8e91f17199dce8605210acf04c 448 SUPERFAMILY SSF103473 4 422 5.36E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01555 7dbd4f8e91f17199dce8605210acf04c 448 Pfam PF00083 Sugar (and other) transporter 230 424 1.5E-10 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 hmeg3_RS01555 7dbd4f8e91f17199dce8605210acf04c 448 Pfam PF00083 Sugar (and other) transporter 7 215 1.1E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 hmeg3_RS01555 7dbd4f8e91f17199dce8605210acf04c 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 287 304 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 PIRSF PIRSF005925 505 951 2.3E-145 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 PIRSF PIRSF005925 376 514 2.1E-10 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 SUPERFAMILY SSF55073 520 678 4.24E-50 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Pfam PF00990 Diguanylate cyclase, GGDEF domain 515 671 9.0E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 SMART SM00267 504 676 4.7E-62 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Gene3D G3DSA:3.30.450.20 359 519 2.6E-27 T 28-03-2018 hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Gene3D G3DSA:3.30.70.270 520 679 4.1E-59 T 28-03-2018 hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 SUPERFAMILY SSF55785 394 502 2.09E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Pfam PF13426 PAS domain 400 502 3.4E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Pfam PF00563 EAL domain 693 927 2.0E-76 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Gene3D G3DSA:3.20.20.450 680 946 6.9E-113 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 Pfam PF03924 CHASE domain 79 271 1.8E-39 T 28-03-2018 IPR006189 CHASE domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 SMART SM00052 686 932 9.1E-137 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 388 511 5.1E-16 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 SMART SM01079 75 273 1.1E-47 T 28-03-2018 IPR006189 CHASE domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 SUPERFAMILY SSF141868 691 939 7.98E-100 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23300 8e7be2d7db6b3ba52c4565f242d5d3d1 953 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 511 674 3.2E-44 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 Gene3D G3DSA:3.40.50.300 311 557 3.1E-38 T 28-03-2018 hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 Pfam PF00005 ABC transporter 344 479 2.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 5 529 2.1E-133 T 28-03-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 SMART SM00382 351 530 6.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 Gene3D G3DSA:1.20.1560.10 1 310 6.7E-26 T 28-03-2018 hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 SUPERFAMILY SSF52540 322 541 2.25E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 SUPERFAMILY SSF90123 5 298 4.32E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS11685 dacb3b4ec974542f5936b2c8eb55e827 560 Pfam PF00664 ABC transporter transmembrane region 34 253 8.5E-8 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS17040 1228d5157e3f9f001ba390d096800735 420 Gene3D G3DSA:3.40.1480.10 244 420 1.2E-67 T 28-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 hmeg3_RS17040 1228d5157e3f9f001ba390d096800735 420 SUPERFAMILY SSF82544 2 419 2.35E-152 T 28-03-2018 hmeg3_RS17040 1228d5157e3f9f001ba390d096800735 420 Pfam PF13660 Domain of unknown function (DUF4147) 9 228 2.6E-83 T 28-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 hmeg3_RS17040 1228d5157e3f9f001ba390d096800735 420 Gene3D G3DSA:3.40.50.10180 16 243 2.1E-90 T 28-03-2018 hmeg3_RS17040 1228d5157e3f9f001ba390d096800735 420 Pfam PF05161 MOFRL family 308 413 1.8E-37 T 28-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Gene3D G3DSA:2.170.190.11 75 150 8.8E-26 T 28-03-2018 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Pfam PF00994 Probable molybdopterin binding domain 200 337 8.0E-31 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 SUPERFAMILY SSF63882 19 194 3.27E-52 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Gene3D G3DSA:2.40.340.10 350 422 9.1E-22 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Pfam PF03454 MoeA C-terminal region (domain IV) 352 424 1.1E-19 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 195 334 6.9E-31 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Gene3D G3DSA:3.40.980.10 180 346 1.3E-53 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 SMART SM00852 198 339 5.1E-45 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 SUPERFAMILY SSF63867 348 426 7.59E-24 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Pfam PF03453 MoeA N-terminal region (domain I and II) 22 185 3.7E-43 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Gene3D G3DSA:3.90.105.10 40 74 1.7E-9 T 28-03-2018 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 Gene3D G3DSA:3.90.105.10 151 179 2.4E-10 T 28-03-2018 hmeg3_RS09080 0a209b78f0397b4f1e232a8d1b779fb8 428 SUPERFAMILY SSF53218 195 342 5.37E-44 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 Gene3D G3DSA:3.20.20.60 1 82 1.1E-16 T 28-03-2018 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 Gene3D G3DSA:3.20.20.60 167 323 1.1E-51 T 28-03-2018 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 Gene3D G3DSA:2.40.33.10 83 166 1.1E-22 T 28-03-2018 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 474 1.8E-148 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 Pfam PF02887 Pyruvate kinase, alpha/beta domain 360 472 2.5E-27 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 SUPERFAMILY SSF50800 71 164 2.09E-24 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 SUPERFAMILY SSF51621 166 340 4.54E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 SUPERFAMILY SSF51621 2 76 4.54E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 Pfam PF00224 Pyruvate kinase, barrel domain 3 340 5.5E-111 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 246 270 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 219 245 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 271 295 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 296 314 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 PRINTS PR01050 Pyruvate kinase family signature 315 331 1.1E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 SUPERFAMILY SSF52935 325 475 3.4E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS20080 70e54d18f7c6e75f76c9c66b852a353a 477 Gene3D G3DSA:3.40.1380.20 324 475 2.1E-43 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS12215 0d68bde93336936b600d34ade04a5ffa 246 Gene3D G3DSA:3.40.630.40 13 243 4.2E-45 T 28-03-2018 hmeg3_RS12215 0d68bde93336936b600d34ade04a5ffa 246 SUPERFAMILY SSF53187 15 237 2.86E-48 T 28-03-2018 hmeg3_RS12215 0d68bde93336936b600d34ade04a5ffa 246 Pfam PF05013 N-formylglutamate amidohydrolase 15 217 5.9E-26 T 28-03-2018 IPR007709 N-formylglutamate amidohydrolase hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 SMART SM00382 42 233 2.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 323 1.0E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 SUPERFAMILY SSF52540 11 255 9.57E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 Gene3D G3DSA:3.40.50.300 8 327 8.9E-82 T 28-03-2018 hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 304 6.3E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS14165 c8a8a5f56eb046f15f69d4ce2b5b7aea 329 Pfam PF00005 ABC transporter 34 184 3.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 SUPERFAMILY SSF46785 2 80 6.53E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 Gene3D G3DSA:3.40.190.10 91 184 4.9E-12 T 28-03-2018 hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 Pfam PF03466 LysR substrate binding domain 93 298 1.2E-24 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 SUPERFAMILY SSF53850 91 297 1.57E-40 T 28-03-2018 hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 64 2.0E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 Gene3D G3DSA:3.40.190.10 185 270 8.7E-22 T 28-03-2018 hmeg3_RS23565 c657e368266aea164f1a6a66ba0c1120 302 Gene3D G3DSA:1.10.10.10 1 84 2.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07935 74291095526b795ea6ef6205570ce43a 236 SUPERFAMILY SSF52540 6 223 4.96E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07935 74291095526b795ea6ef6205570ce43a 236 Pfam PF00005 ABC transporter 27 180 8.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07935 74291095526b795ea6ef6205570ce43a 236 SMART SM00382 32 228 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07935 74291095526b795ea6ef6205570ce43a 236 Gene3D G3DSA:3.40.50.300 1 234 1.1E-49 T 28-03-2018 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 10 301 43.762 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 PIRSF PIRSF001365 6 303 1.0E-55 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 SMART SM01130 10 301 1.6E-79 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 Pfam PF00701 Dihydrodipicolinate synthetase family 12 297 2.5E-52 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 3 299 2.0E-129 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 SUPERFAMILY SSF51569 10 300 4.71E-67 T 28-03-2018 hmeg3_RS12170 b7b7ca965cdc6cad8d1f6a5faad111ae 303 Gene3D G3DSA:3.20.20.70 5 302 2.6E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Gene3D G3DSA:3.30.450.20 134 287 1.3E-23 T 28-03-2018 hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Gene3D G3DSA:3.30.450.20 1 133 1.1E-13 T 28-03-2018 hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Pfam PF13426 PAS domain 4 107 0.013 T 28-03-2018 IPR000014 PAS domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 SUPERFAMILY SSF55874 355 481 1.13E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 SMART SM00086 65 108 0.019 T 28-03-2018 IPR001610 PAC motif hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 SMART SM00086 213 255 5.0E-9 T 28-03-2018 IPR001610 PAC motif hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 SUPERFAMILY SSF55785 145 257 1.68E-19 T 28-03-2018 IPR000014 PAS domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 71 115 1.2E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 262 2.8E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 484 1.6E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Gene3D G3DSA:3.30.565.10 349 486 5.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 SUPERFAMILY SSF55785 4 117 4.36E-11 T 28-03-2018 IPR000014 PAS domain hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Pfam PF08447 PAS fold 161 248 4.6E-17 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS01625 37d383fbbcffd8fbdc5f3f24b288c82e 486 Pfam PF07730 Histidine kinase 283 351 1.1E-9 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS19035 27b1e743890465fee09e9d369cac1764 325 Pfam PF05035 2-keto-3-deoxy-galactonokinase 13 316 2.4E-100 T 28-03-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 hmeg3_RS19035 27b1e743890465fee09e9d369cac1764 325 Gene3D G3DSA:3.30.420.40 1 224 1.0E-5 T 28-03-2018 hmeg3_RS07640 e7eff54a5bc776b651f872568c84e043 152 Gene3D G3DSA:3.30.1330.40 1 152 1.6E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS07640 e7eff54a5bc776b651f872568c84e043 152 SUPERFAMILY SSF55298 1 151 2.67E-50 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS07640 e7eff54a5bc776b651f872568c84e043 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 151 5.8E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS12815 be62ef7f5128e01de65dfb4c906fc97c 147 PIRSF PIRSF002030 19 147 5.6E-32 T 28-03-2018 IPR016339 Truncated hemoglobin, group 1 hmeg3_RS12815 be62ef7f5128e01de65dfb4c906fc97c 147 Pfam PF01152 Bacterial-like globin 32 144 4.8E-13 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 hmeg3_RS12815 be62ef7f5128e01de65dfb4c906fc97c 147 SUPERFAMILY SSF46458 24 144 7.4E-26 T 28-03-2018 IPR009050 Globin-like hmeg3_RS12815 be62ef7f5128e01de65dfb4c906fc97c 147 Gene3D G3DSA:1.10.490.10 32 147 2.6E-28 T 28-03-2018 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 Gene3D G3DSA:2.40.160.10 9 407 4.3E-65 T 28-03-2018 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 SUPERFAMILY SSF56935 21 281 2.66E-70 T 28-03-2018 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 SUPERFAMILY SSF56935 309 407 2.66E-70 T 28-03-2018 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 PRINTS PR00184 Neisseria sp. porin signature 62 87 2.6E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 PRINTS PR00184 Neisseria sp. porin signature 352 376 2.6E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 355 372 3.6E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 171 182 3.6E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 253 265 3.6E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 60 71 3.6E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS09540 2c0791f1652c0f7dfa5475eb49d71e69 407 Pfam PF13609 Gram-negative porin 9 379 3.1E-44 T 28-03-2018 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 SUPERFAMILY SSF50156 148 239 4.21E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 SMART SM00228 272 362 2.6E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 SMART SM00228 148 230 1.7E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 Gene3D G3DSA:2.30.42.10 271 379 4.7E-17 T 28-03-2018 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 Gene3D G3DSA:2.30.42.10 146 247 4.9E-22 T 28-03-2018 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 SUPERFAMILY SSF50156 288 372 8.15E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 Pfam PF13180 PDZ domain 302 371 2.0E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06415 7e06e6d9fc28b026570fc5c4f6aa202a 485 Pfam PF13180 PDZ domain 170 238 8.7E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS12125 b3248fa9330a075732755c8232a7b4e1 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 306 6.7E-78 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS12125 b3248fa9330a075732755c8232a7b4e1 321 Gene3D G3DSA:3.40.50.1100 160 321 8.2E-36 T 28-03-2018 hmeg3_RS12125 b3248fa9330a075732755c8232a7b4e1 321 Gene3D G3DSA:3.40.50.1100 12 159 2.0E-40 T 28-03-2018 hmeg3_RS12125 b3248fa9330a075732755c8232a7b4e1 321 SUPERFAMILY SSF53686 6 312 3.67E-96 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 Pfam PF00920 Dehydratase family 34 611 7.1E-216 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 Gene3D G3DSA:3.40.50.2300 55 186 4.3E-5 T 28-03-2018 hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 SUPERFAMILY SSF52016 425 616 1.73E-57 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 SUPERFAMILY SSF143975 4 424 2.88E-131 T 28-03-2018 hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 614 2.6E-246 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 513 524 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS01660 214e1dcf4ce06cb44b96d43445ba7359 620 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 614 44.555 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS15055 11396ae209b5522a20821f2cc8fa5b18 359 Gene3D G3DSA:3.40.50.1970 7 166 5.1E-37 T 28-03-2018 hmeg3_RS15055 11396ae209b5522a20821f2cc8fa5b18 359 Gene3D G3DSA:1.20.1090.10 167 358 2.5E-50 T 28-03-2018 hmeg3_RS15055 11396ae209b5522a20821f2cc8fa5b18 359 Pfam PF00465 Iron-containing alcohol dehydrogenase 16 343 2.8E-78 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 hmeg3_RS15055 11396ae209b5522a20821f2cc8fa5b18 359 SUPERFAMILY SSF56796 14 355 7.46E-90 T 28-03-2018 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Hamap MF_01262 CCA-adding enzyme [cca]. 1 399 40.085 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Pfam PF01743 Poly A polymerase head domain 3 121 1.3E-16 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 SUPERFAMILY SSF81301 1 119 7.52E-31 T 28-03-2018 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 147 210 6.4E-12 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 SUPERFAMILY SSF81891 121 359 1.19E-50 T 28-03-2018 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Pfam PF01966 HD domain 229 306 2.1E-8 T 28-03-2018 IPR006674 HD domain hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 PIRSF PIRSF000813 1 407 1.3E-189 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 406 51.617 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Gene3D G3DSA:1.10.3090.10 119 405 1.8E-50 T 28-03-2018 hmeg3_RS02915 cafd6479a565e021728d0c21b8e430f8 407 Gene3D G3DSA:3.30.460.10 1 118 8.1E-29 T 28-03-2018 hmeg3_RS15290 31ca6ca2b70efa3538f4fbc956008172 257 Pfam PF01925 Sulfite exporter TauE/SafE 6 255 3.1E-41 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 Pfam PF13377 Periplasmic binding protein-like domain 166 327 3.8E-42 T 28-03-2018 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 8.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 8.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 Gene3D G3DSA:3.40.50.2300 55 172 1.6E-40 T 28-03-2018 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 SUPERFAMILY SSF47413 1 59 7.32E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 SUPERFAMILY SSF53822 61 328 3.08E-88 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 Gene3D G3DSA:1.10.260.40 2 54 1.3E-20 T 28-03-2018 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.6E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 SMART SM00354 1 71 1.2E-33 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 Gene3D G3DSA:3.40.50.2300 173 330 5.4E-50 T 28-03-2018 hmeg3_RS07020 efed2e12ed07c975818c6988c0ca96bf 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 1.8E-123 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 Gene3D G3DSA:3.40.50.720 1 124 2.3E-38 T 28-03-2018 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 Gene3D G3DSA:3.40.50.261 125 293 4.5E-48 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 293 39.535 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 Pfam PF00549 CoA-ligase 156 267 1.1E-14 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 SMART SM00881 4 103 3.2E-28 T 28-03-2018 IPR003781 CoA-binding GO:0048037 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 Pfam PF02629 CoA binding domain 6 102 9.6E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 SUPERFAMILY SSF52210 128 292 1.83E-52 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 SUPERFAMILY SSF51735 1 127 3.01E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 PIRSF PIRSF001553 1 293 5.7E-113 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 1.7E-31 T 28-03-2018 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 1.7E-31 T 28-03-2018 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 1.7E-31 T 28-03-2018 hmeg3_RS20145 8790cd63ede5fb8d5d167b0004dfb106 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 1.7E-31 T 28-03-2018 hmeg3_RS16335 5a7e7d5a745777a84dfe3879b69a129e 453 Gene3D G3DSA:3.90.1300.10 4 451 1.3E-115 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS16335 5a7e7d5a745777a84dfe3879b69a129e 453 SUPERFAMILY SSF75304 4 451 7.98E-114 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS16335 5a7e7d5a745777a84dfe3879b69a129e 453 Pfam PF01425 Amidase 21 441 1.0E-78 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 PIRSF PIRSF001220 26 356 1.0E-84 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 17 353 1.5E-121 T 28-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 PRINTS PR00139 Asparaginase/glutaminase family signature 112 130 8.2E-21 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 PRINTS PR00139 Asparaginase/glutaminase family signature 290 308 8.2E-21 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 PRINTS PR00139 Asparaginase/glutaminase family signature 32 43 8.2E-21 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 PIRSF PIRSF500176 28 356 2.4E-73 T 28-03-2018 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 Gene3D G3DSA:3.40.50.40 243 355 2.8E-22 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 113 123 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 Gene3D G3DSA:3.40.50.1170 27 239 1.6E-53 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 SUPERFAMILY SSF53774 31 355 4.32E-95 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 34 42 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 SMART SM00870 31 350 7.4E-132 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS17630 1ba002c007d51b77056304d9721a494a 356 Pfam PF00710 Asparaginase, N-terminal 31 221 2.6E-55 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 Pfam PF03466 LysR substrate binding domain 97 299 2.3E-24 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 Gene3D G3DSA:1.10.10.10 2 91 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 SUPERFAMILY SSF46785 6 86 1.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 Gene3D G3DSA:3.40.190.10 184 271 1.0E-16 T 28-03-2018 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 SUPERFAMILY SSF53850 91 298 1.43E-42 T 28-03-2018 hmeg3_RS18545 b7bc11108b940c9bc58fe0c82e9931b3 301 Gene3D G3DSA:3.40.190.10 95 183 1.7E-11 T 28-03-2018 hmeg3_RS15060 3b9c2d411b92348657584e4f4e65ecdb 287 Pfam PF04444 Catechol dioxygenase N terminus 23 95 1.8E-30 T 28-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 hmeg3_RS15060 3b9c2d411b92348657584e4f4e65ecdb 287 Gene3D G3DSA:2.60.130.10 1 287 6.9E-82 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS15060 3b9c2d411b92348657584e4f4e65ecdb 287 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 129 157 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 hmeg3_RS15060 3b9c2d411b92348657584e4f4e65ecdb 287 Pfam PF00775 Dioxygenase 101 285 1.9E-54 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 hmeg3_RS15060 3b9c2d411b92348657584e4f4e65ecdb 287 SUPERFAMILY SSF49482 1 286 1.31E-91 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 23 331 2.0E-149 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 Gene3D G3DSA:3.40.190.10 132 251 4.2E-28 T 28-03-2018 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 Gene3D G3DSA:3.40.190.10 252 334 2.5E-25 T 28-03-2018 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 SUPERFAMILY SSF53850 26 332 7.91E-90 T 28-03-2018 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 Gene3D G3DSA:3.40.190.10 25 131 2.8E-22 T 28-03-2018 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 151 159 - T 28-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 hmeg3_RS14480 3ace097831614483450e067cd000980b 337 Pfam PF13531 Bacterial extracellular solute-binding protein 40 285 1.7E-43 T 28-03-2018 hmeg3_RS08445 ecac097b135442adfe59f081283ad879 373 Gene3D G3DSA:3.40.640.10 1 239 1.8E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS08445 ecac097b135442adfe59f081283ad879 373 Gene3D G3DSA:3.90.1150.10 240 373 2.4E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS08445 ecac097b135442adfe59f081283ad879 373 SUPERFAMILY SSF53383 5 372 1.88E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS08445 ecac097b135442adfe59f081283ad879 373 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 368 1.9E-111 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS08445 ecac097b135442adfe59f081283ad879 373 PIRSF PIRSF000390 1 373 8.4E-104 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS09590 bc5c147864ce03ba7fd0df1cdb709724 418 Gene3D G3DSA:1.10.150.130 104 229 7.7E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS09590 bc5c147864ce03ba7fd0df1cdb709724 418 SUPERFAMILY SSF56349 115 400 8.54E-51 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS09590 bc5c147864ce03ba7fd0df1cdb709724 418 Pfam PF13356 Arm DNA-binding domain 8 101 3.6E-17 T 28-03-2018 IPR025166 Integrase, DNA-binding domain hmeg3_RS09590 bc5c147864ce03ba7fd0df1cdb709724 418 Pfam PF00589 Phage integrase family 238 359 6.9E-14 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS09590 bc5c147864ce03ba7fd0df1cdb709724 418 Gene3D G3DSA:1.10.443.10 230 400 1.5E-19 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 SUPERFAMILY SSF52518 27 215 5.3E-20 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 Gene3D G3DSA:3.40.50.920 280 418 7.7E-9 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 SUPERFAMILY SSF52922 275 416 6.54E-8 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 Gene3D G3DSA:3.40.50.970 464 655 3.3E-30 T 28-03-2018 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 759 946 4.5E-26 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 Gene3D G3DSA:3.40.50.970 11 235 5.4E-20 T 28-03-2018 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 SUPERFAMILY SSF53323 750 999 3.53E-36 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 Gene3D G3DSA:3.40.920.10 749 963 4.6E-49 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 480 563 6.3E-6 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 hmeg3_RS02930 41778ee23b70cf3984727f23b03696f3 1199 SUPERFAMILY SSF52518 460 639 9.57E-13 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS12660 dbb5232fa2cfe057766f176a0a311c60 312 Pfam PF00698 Acyl transferase domain 8 284 2.7E-15 T 28-03-2018 IPR014043 Acyl transferase hmeg3_RS12660 dbb5232fa2cfe057766f176a0a311c60 312 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 306 3.6E-12 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain hmeg3_RS12660 dbb5232fa2cfe057766f176a0a311c60 312 Gene3D G3DSA:3.40.366.10 1 291 1.7E-36 T 28-03-2018 hmeg3_RS12660 dbb5232fa2cfe057766f176a0a311c60 312 SUPERFAMILY SSF52151 5 123 9.16E-41 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS12660 dbb5232fa2cfe057766f176a0a311c60 312 SUPERFAMILY SSF52151 187 307 9.16E-41 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS17005 2ec79b8314fbc35e71d53dea91a32b34 453 Gene3D G3DSA:2.30.40.10 1 74 7.4E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS17005 2ec79b8314fbc35e71d53dea91a32b34 453 Gene3D G3DSA:3.20.20.140 75 391 3.5E-63 T 28-03-2018 hmeg3_RS17005 2ec79b8314fbc35e71d53dea91a32b34 453 SUPERFAMILY SSF51338 5 61 2.94E-25 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS17005 2ec79b8314fbc35e71d53dea91a32b34 453 SUPERFAMILY SSF51338 374 447 2.94E-25 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS17005 2ec79b8314fbc35e71d53dea91a32b34 453 SUPERFAMILY SSF51556 61 374 2.9E-97 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS17005 2ec79b8314fbc35e71d53dea91a32b34 453 Pfam PF01979 Amidohydrolase family 58 422 1.4E-62 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 Gene3D G3DSA:3.40.50.720 7 52 1.7E-6 T 28-03-2018 hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 Gene3D G3DSA:3.40.50.720 53 262 3.8E-58 T 28-03-2018 hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 SUPERFAMILY SSF51735 14 258 7.25E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 2.6E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06420 1e1b90eba0775a58eeba4d9afc9d6ce2 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 258 2.8E-59 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:1.10.1200.10 1065 1131 9.2E-18 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.559.10 64 295 1.3E-40 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.559.10 1560 1806 5.3E-40 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.559.10 3066 3305 7.0E-28 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 93 271 7.0E-42 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 3113 3284 2.33E-34 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF47336 1054 1124 5.89E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 1774 2022 2.78E-48 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 2847 3095 5.45E-28 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2202 2213 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF56801 539 1072 5.1E-126 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00550 Phosphopantetheine attachment site 1062 1124 2.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00550 Phosphopantetheine attachment site 2568 2630 2.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 1585 1788 2.08E-44 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF47336 2563 2622 1.03E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.300.30 2448 2572 3.1E-34 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.300.30 943 1064 5.9E-31 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.40.50.980 2202 2352 3.2E-30 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:1.10.1200.10 2573 2635 2.7E-17 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.559.10 2636 2829 2.0E-30 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.30.559.10 1132 1325 4.3E-26 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 277 519 1.17E-54 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 1318 1576 1.56E-22 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1084 1099 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2073 2477 3.8E-122 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 568 972 2.4E-107 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.40.50.980 687 862 9.9E-37 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:2.30.38.10 2362 2443 2.1E-24 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2591 2606 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:2.30.38.10 863 940 1.8E-17 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.40.50.980 2045 2201 7.2E-39 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Gene3D G3DSA:3.40.50.980 540 686 2.5E-34 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF13193 AMP-binding enzyme C-terminal domain 956 1029 1.2E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF13193 AMP-binding enzyme C-terminal domain 2461 2538 3.3E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SMART SM00823 Phosphopantetheine attachment site 1060 1128 0.0031 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SMART SM00823 Phosphopantetheine attachment site 2567 2637 0.061 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF56801 2043 2580 3.14E-141 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 2659 2836 4.22E-35 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 3285 3519 5.45E-43 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 685 696 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00501 AMP-binding enzyme 549 948 3.0E-75 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00501 AMP-binding enzyme 2053 2453 4.3E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 SUPERFAMILY SSF52777 1148 1310 1.03E-28 T 28-03-2018 hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00668 Condensation domain 3112 3517 2.4E-56 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00668 Condensation domain 2656 3094 1.3E-49 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00668 Condensation domain 1589 2030 6.2E-83 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11700 4d3c9cc7da887a25042f5a25ef670bfa 3531 Pfam PF00668 Condensation domain 88 528 9.6E-90 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 SUPERFAMILY SSF51735 100 288 6.84E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 SUPERFAMILY SSF52283 1 133 8.29E-26 T 28-03-2018 hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 317 1.5E-22 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 Gene3D G3DSA:3.40.50.720 114 288 1.4E-54 T 28-03-2018 hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 8.5E-62 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS16065 c3a6ab46d6bfef39b6b3d506450e3a9b 319 Gene3D G3DSA:3.40.50.720 2 113 1.2E-25 T 28-03-2018 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 SUPERFAMILY SSF103039 52 230 6.54E-22 T 28-03-2018 IPR028976 CheC-like domain hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 8.2E-26 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 89 105 8.2E-26 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 114 133 8.2E-26 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 8.2E-26 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 Pfam PF02154 Flagellar motor switch protein FliM 38 230 1.5E-69 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 PIRSF PIRSF002888 2 329 1.1E-94 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 Gene3D G3DSA:2.30.330.10 239 331 9.9E-17 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 Gene3D G3DSA:3.40.1550.10 46 235 1.4E-40 T 28-03-2018 IPR028976 CheC-like domain hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 SUPERFAMILY SSF101801 249 321 6.02E-14 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 319 7.4E-103 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 hmeg3_RS08285 9b1270388527c264d5100b12cd5c8c37 337 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 251 320 6.9E-20 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 SUPERFAMILY SSF51735 7 158 2.29E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 134 288 4.1E-65 T 28-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 Gene3D G3DSA:3.30.360.10 149 288 4.7E-70 T 28-03-2018 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 314 143.757 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 SUPERFAMILY SSF55347 134 288 2.75E-66 T 28-03-2018 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 SMART SM00859 10 126 1.1E-11 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 Gene3D G3DSA:3.40.50.720 3 148 3.9E-11 T 28-03-2018 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 8 312 8.8E-142 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 PIRSF PIRSF015689 5 314 3.6E-133 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 hmeg3_RS19560 4e185637090f150d418eedad36fff9bc 314 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 11 123 7.3E-14 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Pfam PF00990 Diguanylate cyclase, GGDEF domain 622 778 2.2E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Pfam PF13185 GAF domain 466 610 1.4E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SMART SM00065 467 619 0.0022 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Gene3D G3DSA:3.30.450.20 155 282 7.4E-4 T 28-03-2018 hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SMART SM00052 793 1039 2.3E-112 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SMART SM00091 330 397 0.0014 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Gene3D G3DSA:3.30.70.270 620 786 2.6E-59 T 28-03-2018 hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SMART SM00267 611 783 1.8E-61 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Pfam PF00563 EAL domain 799 1034 3.0E-74 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SUPERFAMILY SSF141868 798 1048 1.57E-87 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 619 781 2.1E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Gene3D G3DSA:3.30.450.40 450 619 1.0E-16 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 327 449 1.3E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SUPERFAMILY SSF55781 467 622 8.72E-16 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SUPERFAMILY SSF55073 627 785 9.42E-49 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 SUPERFAMILY SSF55785 320 443 1.92E-12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Gene3D G3DSA:3.30.450.20 313 449 1.9E-15 T 28-03-2018 hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Gene3D G3DSA:3.20.20.450 787 1051 1.3E-98 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12865 33d64ef1b3306f6da12e5addb232dc3d 1052 Pfam PF08448 PAS fold 339 447 1.1E-5 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Gene3D G3DSA:3.40.50.670 432 829 2.1E-105 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Pfam PF01751 Toprim domain 451 563 1.4E-18 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 761 821 6.2E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 SUPERFAMILY SSF54211 248 423 3.22E-55 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 14 832 96.846 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 44 202 6.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Gene3D G3DSA:3.30.230.10 252 424 9.4E-61 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 SUPERFAMILY SSF55874 16 244 1.96E-65 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 17 832 2.6E-285 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Gene3D G3DSA:3.30.565.10 11 251 3.5E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 SMART SM00433 47 825 4.5E-244 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 SMART SM00387 43 203 4.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 ProSitePatterns PS00177 DNA topoisomerase II signature. 454 462 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 557 569 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 537 554 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 519 535 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 452 466 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 47 62 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 764 780 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 82 95 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 129 143 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR00418 DNA topoisomerase II family signature 300 313 1.6E-66 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 223 236 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 785 797 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 502 511 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 406 426 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 801 817 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 208 223 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 17 27 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 247 269 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 274 292 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 392 406 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 PRINTS PR01159 DNA gyrase subunit B signature 344 360 2.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 Pfam PF00204 DNA gyrase B 248 422 1.4E-57 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 SUPERFAMILY SSF56719 758 821 1.23E-83 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 hmeg3_RS24275 c27441aaedc7c6ce0be670d2d208285e 832 SUPERFAMILY SSF56719 426 592 1.23E-83 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 SMART SM00014 73 183 2.9E-12 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 245 253 1.1E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 291 306 1.1E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 327 343 1.1E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 Pfam PF01569 PAP2 superfamily 74 186 4.1E-21 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 199 352 15.708 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 Gene3D G3DSA:1.20.144.10 14 187 6.0E-24 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 SUPERFAMILY SSF48317 9 194 1.83E-33 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 Pfam PF01252 Signal peptidase (SPase) II 208 345 6.0E-35 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS11835 17dfe536b882136fc50ca584580334e0 359 TIGRFAM TIGR00077 lspA: signal peptidase II 199 350 2.7E-40 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS00615 76e085f0bb735fb8aa72853469a04e55 143 SUPERFAMILY SSF46955 3 113 2.49E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS00615 76e085f0bb735fb8aa72853469a04e55 143 Gene3D G3DSA:1.10.1660.10 1 59 6.5E-19 T 28-03-2018 hmeg3_RS00615 76e085f0bb735fb8aa72853469a04e55 143 SMART SM00422 4 74 1.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS00615 76e085f0bb735fb8aa72853469a04e55 143 Gene3D G3DSA:1.10.1660.10 60 143 6.8E-13 T 28-03-2018 hmeg3_RS00615 76e085f0bb735fb8aa72853469a04e55 143 Pfam PF13411 MerR HTH family regulatory protein 4 72 1.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS16980 b781d9fdf6709d1e56962d9f8070292e 544 Gene3D G3DSA:1.10.275.10 2 207 4.4E-59 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS16980 b781d9fdf6709d1e56962d9f8070292e 544 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 hmeg3_RS16980 b781d9fdf6709d1e56962d9f8070292e 544 Gene3D G3DSA:1.20.200.10 209 542 1.2E-104 T 28-03-2018 hmeg3_RS16980 b781d9fdf6709d1e56962d9f8070292e 544 SUPERFAMILY SSF48557 3 533 6.2E-158 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS16980 b781d9fdf6709d1e56962d9f8070292e 544 Pfam PF00221 Aromatic amino acid lyase 11 504 3.7E-159 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:1.10.1200.10 1253 1330 8.9E-17 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Pfam PF08659 KR domain 945 1113 4.3E-33 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.40.50.720 715 918 0.32 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:2.30.38.10 520 601 9.2E-17 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Pfam PF00501 AMP-binding enzyme 198 609 3.2E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 SUPERFAMILY SSF51735 738 931 6.3E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.40.50.720 937 1171 1.2E-29 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.40.50.980 186 355 1.4E-21 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.30.300.30 602 714 8.1E-15 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 SUPERFAMILY SSF56801 187 719 1.57E-91 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.30.300.30 1201 1242 0.15 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.30.300.30 32 124 0.047 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 SUPERFAMILY SSF47336 1251 1322 8.11E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Gene3D G3DSA:3.40.50.980 356 519 1.0E-27 T 28-03-2018 hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 SUPERFAMILY SSF51735 942 1166 7.87E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 Pfam PF00550 Phosphopantetheine attachment site 1259 1321 8.0E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 ProSitePatterns PS00455 Putative AMP-binding domain signature. 349 360 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11690 2e8e30105379221c29131413e745f982 1358 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 945 1128 4.1E-16 T 28-03-2018 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 1.5E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 Gene3D G3DSA:1.10.10.10 3 89 7.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 SUPERFAMILY SSF53850 96 301 2.34E-40 T 28-03-2018 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 SUPERFAMILY SSF46785 6 116 2.12E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 3.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 3.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 3.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 Pfam PF03466 LysR substrate binding domain 94 296 4.9E-41 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 Gene3D G3DSA:3.40.190.10 182 273 1.6E-22 T 28-03-2018 hmeg3_RS03695 cdce341481f52b470a452a5a72b2e703 306 Gene3D G3DSA:3.40.190.10 95 181 2.3E-22 T 28-03-2018 hmeg3_RS21555 d82d97f2677dc2d0e3ed02088c9ca7d5 637 Pfam PF01964 Radical SAM ThiC family 139 599 4.2E-199 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 hmeg3_RS21555 d82d97f2677dc2d0e3ed02088c9ca7d5 637 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 137 604 56.418 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 hmeg3_RS21555 d82d97f2677dc2d0e3ed02088c9ca7d5 637 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 137 602 1.2E-216 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 hmeg3_RS21555 d82d97f2677dc2d0e3ed02088c9ca7d5 637 Pfam PF13667 ThiC-associated domain 21 97 1.9E-32 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 hmeg3_RS06135 cb03b40a763048aa22d81864c25e0770 255 SUPERFAMILY SSF55729 20 224 1.31E-41 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS06135 cb03b40a763048aa22d81864c25e0770 255 Gene3D G3DSA:3.40.630.30 16 201 1.2E-37 T 28-03-2018 hmeg3_RS06135 cb03b40a763048aa22d81864c25e0770 255 Pfam PF13444 Acetyltransferase (GNAT) domain 34 135 5.9E-35 T 28-03-2018 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 Pfam PF01048 Phosphorylase superfamily 280 446 1.3E-13 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 10 499 5.5E-196 T 28-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 11 164 4.7E-54 T 28-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 Gene3D G3DSA:3.40.50.1580 176 481 1.3E-65 T 28-03-2018 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 SUPERFAMILY SSF53167 7 499 5.11E-148 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 Gene3D G3DSA:3.30.1730.10 5 165 5.6E-60 T 28-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 hmeg3_RS04240 9e896daa701a9ef50d6b440bb231e12b 499 Hamap MF_01932 AMP nucleosidase [amn]. 2 499 60.742 T 28-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 260 1.3E-11 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Gene3D G3DSA:3.40.50.2300 4 135 1.1E-16 T 28-03-2018 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 SUPERFAMILY SSF55874 351 477 3.01E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Gene3D G3DSA:3.30.565.10 258 479 1.1E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 SMART SM00448 5 116 2.7E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 SUPERFAMILY SSF55785 129 251 3.14E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 SMART SM00387 382 480 9.8E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Gene3D G3DSA:3.30.450.20 136 257 2.7E-21 T 28-03-2018 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 479 4.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 2.6E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 477 2.6E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 2.6E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Pfam PF07730 Histidine kinase 281 344 1.9E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 SMART SM00091 141 207 8.4E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 SUPERFAMILY SSF52172 4 167 1.71E-22 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Pfam PF00072 Response regulator receiver domain 7 112 3.1E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10520 7e6b22c1ee7ad6637807f59c57a7ed02 485 Pfam PF08448 PAS fold 148 254 8.9E-13 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS15220 a6d0e7ec7d0f339dd12003d0286f315c 199 SUPERFAMILY SSF46689 2 82 1.09E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS15220 a6d0e7ec7d0f339dd12003d0286f315c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS15220 a6d0e7ec7d0f339dd12003d0286f315c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS15220 a6d0e7ec7d0f339dd12003d0286f315c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS15220 a6d0e7ec7d0f339dd12003d0286f315c 199 Gene3D G3DSA:1.10.10.60 1 52 3.6E-17 T 28-03-2018 hmeg3_RS15220 a6d0e7ec7d0f339dd12003d0286f315c 199 Gene3D G3DSA:1.10.10.60 53 136 6.0E-12 T 28-03-2018 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 Gene3D G3DSA:2.40.50.140 295 342 6.5E-11 T 28-03-2018 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 Gene3D G3DSA:2.40.50.100 240 294 7.9E-12 T 28-03-2018 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 Pfam PF00005 ABC transporter 20 161 6.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 SUPERFAMILY SSF50331 236 359 1.19E-28 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 SMART SM00382 28 211 9.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 Pfam PF08402 TOBE domain 283 351 1.7E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 Gene3D G3DSA:3.40.50.300 1 239 2.8E-70 T 28-03-2018 hmeg3_RS17520 9c1a6c75754333cd4b3d10dae03fa178 362 SUPERFAMILY SSF52540 4 242 9.96E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Gene3D G3DSA:3.30.413.10 406 557 4.5E-32 T 28-03-2018 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 273 1.3E-44 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 547 3.6E-11 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 345 398 4.6E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 49 109 1.4E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Gene3D G3DSA:3.30.413.10 120 237 9.0E-29 T 28-03-2018 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 SUPERFAMILY SSF55124 315 421 6.05E-27 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 SUPERFAMILY SSF55124 252 276 6.05E-27 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 SUPERFAMILY SSF56014 407 549 2.49E-39 T 28-03-2018 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 SUPERFAMILY SSF55124 1 125 1.28E-29 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 SUPERFAMILY SSF56014 120 286 1.31E-50 T 28-03-2018 hmeg3_RS15295 6f2efd03ee9bd27e3b1cf904cd392182 564 Gene3D G3DSA:3.90.480.10 238 405 2.9E-22 T 28-03-2018 hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 Gene3D G3DSA:3.40.190.10 182 259 1.5E-6 T 28-03-2018 hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 SUPERFAMILY SSF46785 2 85 1.42E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 Pfam PF03466 LysR substrate binding domain 91 292 2.5E-20 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 Gene3D G3DSA:3.40.190.10 91 181 3.8E-10 T 28-03-2018 hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 SUPERFAMILY SSF53850 91 293 3.62E-23 T 28-03-2018 hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 Gene3D G3DSA:1.10.10.10 2 86 1.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18435 9c4971545d952ba140271eda492a9f02 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.8E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03795 55b5c6f0047c53f0e5d94b48643fb454 485 Gene3D G3DSA:3.40.309.10 271 466 1.6E-64 T 28-03-2018 hmeg3_RS03795 55b5c6f0047c53f0e5d94b48643fb454 485 Gene3D G3DSA:3.40.605.10 3 270 1.9E-89 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03795 55b5c6f0047c53f0e5d94b48643fb454 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03795 55b5c6f0047c53f0e5d94b48643fb454 485 Pfam PF00171 Aldehyde dehydrogenase family 23 480 1.3E-154 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03795 55b5c6f0047c53f0e5d94b48643fb454 485 SUPERFAMILY SSF53720 12 481 2.49E-155 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03410 f5323eaa17fd16092990acd0283d4317 304 SUPERFAMILY SSF53335 62 194 7.74E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS03410 f5323eaa17fd16092990acd0283d4317 304 Pfam PF13679 Methyltransferase domain 56 196 7.1E-44 T 28-03-2018 IPR025714 Methyltransferase domain hmeg3_RS03410 f5323eaa17fd16092990acd0283d4317 304 Gene3D G3DSA:3.40.50.150 50 284 4.3E-10 T 28-03-2018 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 Gene3D G3DSA:3.40.50.1260 180 381 2.8E-77 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 Gene3D G3DSA:3.40.50.1260 5 179 1.3E-59 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 39.328 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 36 58 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 313 338 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 191 210 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 14 30 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 168 190 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 1.9E-79 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 PIRSF PIRSF000724 1 396 2.2E-138 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 Pfam PF00162 Phosphoglycerate kinase 13 383 1.8E-140 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 19 29 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS20085 b4d8cd2f177dc1aacbfe085e499db4d3 396 SUPERFAMILY SSF53748 10 392 1.06E-141 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 SMART SM00862 146 221 3.9E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 Gene3D G3DSA:1.10.10.10 121 228 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 SUPERFAMILY SSF52172 3 119 5.83E-32 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 Gene3D G3DSA:3.40.50.2300 2 120 5.1E-28 T 28-03-2018 hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 Pfam PF00072 Response regulator receiver domain 4 114 5.8E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 SMART SM00448 2 113 1.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 3.1E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS22260 f8ba46d953142a0f610575310de6c11a 232 SUPERFAMILY SSF46894 124 221 3.97E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 Gene3D G3DSA:3.40.190.10 179 266 1.7E-17 T 28-03-2018 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 Pfam PF03466 LysR substrate binding domain 89 292 4.0E-29 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 SUPERFAMILY SSF53850 86 293 1.44E-29 T 28-03-2018 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 Gene3D G3DSA:1.10.10.10 1 83 4.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.5E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 Gene3D G3DSA:3.40.190.10 88 178 2.2E-12 T 28-03-2018 hmeg3_RS01870 578a98fbd27e604a6266b25a73dfa320 296 SUPERFAMILY SSF46785 1 86 3.31E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04530 9961b5049c0225751997bb1be1f73f10 511 Pfam PF08666 SAF domain 14 83 3.3E-12 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS04530 9961b5049c0225751997bb1be1f73f10 511 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 509 4.0E-163 T 28-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 hmeg3_RS04530 9961b5049c0225751997bb1be1f73f10 511 SMART SM00858 14 84 2.4E-13 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 TIGRFAM TIGR01138 cysM: cysteine synthase B 5 298 2.0E-135 T 28-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 Gene3D G3DSA:3.40.50.1100 44 139 3.7E-35 T 28-03-2018 hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 SUPERFAMILY SSF53686 5 298 7.2E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 Gene3D G3DSA:3.40.50.1100 140 300 6.3E-44 T 28-03-2018 hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 287 1.7E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS05710 4ca5edd6c5c61ce326f0c8314cdaf51a 300 TIGRFAM TIGR01136 cysKM: cysteine synthase 6 298 2.2E-115 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 Gene3D G3DSA:1.10.3810.10 52 249 1.7E-72 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 Pfam PF17092 Penicillin-binding protein OB-like domain 324 428 1.2E-18 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 Pfam PF00912 Transglycosylase 59 237 2.5E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 Gene3D G3DSA:3.40.710.10 250 726 3.8E-121 T 28-03-2018 hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 SUPERFAMILY SSF53955 46 260 5.62E-71 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 SUPERFAMILY SSF56601 219 241 7.27E-121 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 SUPERFAMILY SSF56601 270 321 7.27E-121 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 SUPERFAMILY SSF56601 425 732 7.27E-121 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 69 712 4.5E-184 T 28-03-2018 hmeg3_RS03205 7f50caa810a0d4167393a3984447d6ae 771 Pfam PF00905 Penicillin binding protein transpeptidase domain 431 687 1.8E-37 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 hmeg3_RS16695 740d495acc97469f0a84469ba93e555c 87 Pfam PF05768 Glutaredoxin-like domain (DUF836) 7 83 1.1E-13 T 28-03-2018 IPR008554 Glutaredoxin-like hmeg3_RS16695 740d495acc97469f0a84469ba93e555c 87 Gene3D G3DSA:3.40.30.10 3 84 3.2E-8 T 28-03-2018 hmeg3_RS16695 740d495acc97469f0a84469ba93e555c 87 SUPERFAMILY SSF52833 4 59 1.83E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 9.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 Gene3D G3DSA:1.10.10.10 157 220 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 SUPERFAMILY SSF46894 153 220 2.89E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 Gene3D G3DSA:3.40.50.2300 6 150 4.4E-23 T 28-03-2018 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 Pfam PF00072 Response regulator receiver domain 9 124 9.8E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 SMART SM00448 7 125 2.7E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 SUPERFAMILY SSF52172 8 128 3.84E-21 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15910 3c62768bb1f7103391c10615d9fd9a40 220 SMART SM00421 157 214 7.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 4.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 SUPERFAMILY SSF46785 7 92 1.98E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 Pfam PF03466 LysR substrate binding domain 92 295 2.5E-25 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 SUPERFAMILY SSF53850 97 297 8.87E-27 T 28-03-2018 hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 Gene3D G3DSA:3.40.190.10 97 182 2.8E-10 T 28-03-2018 hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 Gene3D G3DSA:1.10.10.10 6 96 2.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10875 39e9946ad5bb8e7f12822073487249fa 307 Gene3D G3DSA:3.40.190.10 183 264 3.0E-10 T 28-03-2018 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Pfam PF10410 DnaB-helicase binding domain of primase 373 427 1.7E-9 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 SMART SM00766 461 587 1.6E-6 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 TIGRFAM TIGR01391 dnaG: DNA primase 2 421 1.7E-136 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Hamap MF_00974 DNA primase [dnaG]. 1 587 28.367 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 SUPERFAMILY SSF117023 463 589 6.15E-6 T 28-03-2018 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Gene3D G3DSA:1.20.50.20 373 425 2.9E-13 T 28-03-2018 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Pfam PF08278 DNA primase DnaG DnaB-binding 462 586 6.2E-16 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Gene3D G3DSA:3.40.1360.10 245 372 1.4E-31 T 28-03-2018 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 255 8.4E-37 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 SMART SM00493 263 334 2.9E-11 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 SMART SM00400 33 87 4.8E-35 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 PIRSF PIRSF002811 1 597 2.7E-145 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 SUPERFAMILY SSF57783 2 96 8.84E-36 T 28-03-2018 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Pfam PF01807 CHC2 zinc finger 3 97 7.9E-39 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Gene3D G3DSA:3.90.580.10 1 99 1.9E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Gene3D G3DSA:1.10.860.10 444 593 1.8E-22 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Pfam PF13662 Toprim domain 265 329 3.3E-14 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 SUPERFAMILY SSF56731 116 425 1.24E-99 T 28-03-2018 hmeg3_RS19490 3bce9ac70285507f8b166c35ea6a23a4 602 Gene3D G3DSA:3.90.980.10 109 244 2.6E-43 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal hmeg3_RS06165 b2b2d8ced8407911b98a44da6cc99e99 152 SUPERFAMILY SSF53254 2 134 1.22E-19 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS06165 b2b2d8ced8407911b98a44da6cc99e99 152 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 72 1.5E-7 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS06165 b2b2d8ced8407911b98a44da6cc99e99 152 Gene3D G3DSA:3.40.50.1240 1 146 2.8E-19 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS06165 b2b2d8ced8407911b98a44da6cc99e99 152 PIRSF PIRSF000709 3 71 0.0096 T 28-03-2018 hmeg3_RS06165 b2b2d8ced8407911b98a44da6cc99e99 152 PIRSF PIRSF000709 90 119 52.0 T 28-03-2018 hmeg3_RS06165 b2b2d8ced8407911b98a44da6cc99e99 152 SMART SM00855 2 106 4.3E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS10570 7d0e804ec555b1ee03d5b05301dd3f60 417 SUPERFAMILY SSF56801 114 353 3.01E-26 T 28-03-2018 hmeg3_RS10570 7d0e804ec555b1ee03d5b05301dd3f60 417 Pfam PF00501 AMP-binding enzyme 132 280 1.5E-11 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS10570 7d0e804ec555b1ee03d5b05301dd3f60 417 Gene3D G3DSA:3.40.50.980 108 237 3.2E-13 T 28-03-2018 hmeg3_RS05485 8a039a288bea5e71f3f76bc0fd5cf4cb 134 Pfam PF12779 YXWGXW repeat (2 copies) 51 73 2.2E-7 T 28-03-2018 IPR024447 YXWGXW repeat hmeg3_RS12225 c32e12730c0fc9085b1b3b20475816ca 142 SMART SM00448 4 127 1.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12225 c32e12730c0fc9085b1b3b20475816ca 142 Pfam PF00072 Response regulator receiver domain 6 127 8.9E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12225 c32e12730c0fc9085b1b3b20475816ca 142 Gene3D G3DSA:3.40.50.2300 1 141 1.2E-24 T 28-03-2018 hmeg3_RS12225 c32e12730c0fc9085b1b3b20475816ca 142 SUPERFAMILY SSF52172 3 135 1.01E-27 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS24460 9a39326bca7781d77f0becef5aac513a 120 Pfam PF11804 Protein of unknown function (DUF3325) 10 111 9.1E-28 T 28-03-2018 IPR021762 Protein of unknown function DUF3325 hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 Pfam PF00005 ABC transporter 622 769 2.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 Pfam PF00005 ABC transporter 362 516 6.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 ProSitePatterns PS00211 ABC transporters family signature. 742 756 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 SUPERFAMILY SSF52540 606 832 6.63E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 293 5.3E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 SMART SM00382 631 817 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 SMART SM00382 370 587 9.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 Gene3D G3DSA:1.10.3470.10 5 308 1.6E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 SUPERFAMILY SSF52540 345 585 1.92E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 Gene3D G3DSA:3.40.50.300 336 585 8.0E-48 T 28-03-2018 hmeg3_RS17665 0ce35320192feb4855db66b772bd63b8 840 Gene3D G3DSA:3.40.50.300 600 838 1.5E-58 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 474 2.7E-162 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 Gene3D G3DSA:3.40.50.720 180 343 4.6E-36 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 SUPERFAMILY SSF51905 1 347 1.44E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 Gene3D G3DSA:3.30.390.30 344 473 1.7E-42 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 Gene3D G3DSA:3.50.50.60 1 179 9.8E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 356 465 1.1E-37 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 337 1.1E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PIRSF PIRSF000350 1 474 1.1E-81 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 SUPERFAMILY SSF55424 352 473 9.62E-42 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.7E-77 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 2.1E-41 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.1E-41 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.1E-41 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 2.1E-41 T 28-03-2018 hmeg3_RS08790 a4d3ca9d38488bf7104f8766e5371bc1 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 2.1E-41 T 28-03-2018 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Gene3D G3DSA:3.40.1190.10 480 712 4.7E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Gene3D G3DSA:3.90.190.20 713 851 8.4E-22 T 28-03-2018 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 204 287 3.2E-8 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 SUPERFAMILY SSF56059 366 445 3.36E-35 T 28-03-2018 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 SUPERFAMILY SSF56059 204 314 3.36E-35 T 28-03-2018 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Gene3D G3DSA:3.30.470.20 274 479 1.6E-24 T 28-03-2018 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 3 854 0.0 T 28-03-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 SMART SM01209 203 323 0.0098 T 28-03-2018 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 473 496 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 SUPERFAMILY SSF53623 433 722 1.31E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 SUPERFAMILY SSF53244 711 838 4.58E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Gene3D G3DSA:3.30.1490.20 188 273 5.3E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Pfam PF08245 Mur ligase middle domain 475 686 1.7E-19 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS09900 5f9f44413e0a7f20491ae0282406da17 856 Pfam PF02875 Mur ligase family, glutamate ligase domain 711 785 1.5E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS03555 434fb191084662d86d192ad181ae3d46 256 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 7 255 1.2E-56 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 hmeg3_RS03555 434fb191084662d86d192ad181ae3d46 256 Gene3D G3DSA:3.40.1390.30 1 113 3.7E-23 T 28-03-2018 hmeg3_RS03555 434fb191084662d86d192ad181ae3d46 256 SUPERFAMILY SSF102705 7 255 1.19E-73 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 hmeg3_RS03555 434fb191084662d86d192ad181ae3d46 256 Gene3D G3DSA:3.40.1390.30 114 227 4.2E-28 T 28-03-2018 hmeg3_RS03555 434fb191084662d86d192ad181ae3d46 256 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 11 243 2.4E-50 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 hmeg3_RS21830 a20d661d3e54014cd29c2befde4fb6c4 320 SUPERFAMILY SSF53850 26 244 4.04E-43 T 28-03-2018 hmeg3_RS21830 a20d661d3e54014cd29c2befde4fb6c4 320 SMART SM00062 32 251 0.0037 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS21830 a20d661d3e54014cd29c2befde4fb6c4 320 Gene3D G3DSA:3.40.190.10 124 314 4.7E-29 T 28-03-2018 hmeg3_RS21830 a20d661d3e54014cd29c2befde4fb6c4 320 Gene3D G3DSA:3.40.190.10 22 123 2.3E-8 T 28-03-2018 hmeg3_RS21830 a20d661d3e54014cd29c2befde4fb6c4 320 Pfam PF09084 NMT1/THI5 like 52 244 5.9E-26 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Gene3D G3DSA:3.40.50.2300 652 776 6.3E-34 T 28-03-2018 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SUPERFAMILY SSF47226 11 120 1.06E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SUPERFAMILY SSF50341 496 628 6.93E-23 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Pfam PF01627 Hpt domain 11 105 5.2E-12 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SUPERFAMILY SSF55874 321 495 7.07E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Gene3D G3DSA:3.30.565.10 319 498 1.1E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SMART SM00260 489 628 2.0E-13 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Gene3D G3DSA:1.10.287.560 197 300 3.4E-4 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SMART SM00073 8 111 2.4E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SMART SM00387 354 497 3.3E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Pfam PF00072 Response regulator receiver domain 658 770 5.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 496 5.5E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SUPERFAMILY SSF52172 655 774 2.56E-33 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Pfam PF01584 CheW-like domain 503 632 8.4E-16 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 SMART SM00448 656 770 2.3E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Gene3D G3DSA:1.20.120.160 4 191 4.4E-20 T 28-03-2018 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 1.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 1.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 1.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Gene3D G3DSA:2.30.30.40 565 628 3.2E-12 T 28-03-2018 hmeg3_RS14885 a021447709afb3f4258991ce0748a5b7 777 Gene3D G3DSA:2.30.30.40 499 561 0.15 T 28-03-2018 hmeg3_RS12290 49d9e406d8081bb2447fd08e9dc9b05a 445 Pfam PF07690 Major Facilitator Superfamily 39 401 2.8E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS12290 49d9e406d8081bb2447fd08e9dc9b05a 445 Gene3D G3DSA:1.20.1250.20 20 230 6.2E-39 T 28-03-2018 hmeg3_RS12290 49d9e406d8081bb2447fd08e9dc9b05a 445 Gene3D G3DSA:1.20.1250.20 245 445 1.3E-17 T 28-03-2018 hmeg3_RS12290 49d9e406d8081bb2447fd08e9dc9b05a 445 SUPERFAMILY SSF103473 21 442 2.22E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 3.0E-24 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.854 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.7E-14 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.7E-14 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.7E-14 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 Pfam PF01632 Ribosomal protein L35 2 62 1.6E-22 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07760 0d2240dfd47a670f14e91c9284108cae 65 SUPERFAMILY SSF143034 2 63 1.31E-21 T 28-03-2018 hmeg3_RS07185 a0d893d2210bd7bb489337dba3d744db 159 Pfam PF02464 Competence-damaged protein 6 158 1.7E-58 T 28-03-2018 IPR008136 CinA, C-terminal hmeg3_RS07185 a0d893d2210bd7bb489337dba3d744db 159 Gene3D G3DSA:3.90.950.20 2 159 3.3E-57 T 28-03-2018 hmeg3_RS07185 a0d893d2210bd7bb489337dba3d744db 159 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 11 158 3.7E-47 T 28-03-2018 IPR008136 CinA, C-terminal hmeg3_RS07185 a0d893d2210bd7bb489337dba3d744db 159 SUPERFAMILY SSF142433 4 158 5.89E-56 T 28-03-2018 IPR008136 CinA, C-terminal hmeg3_RS16230 73cb11f45e9fbdb16c70ebdff2433999 810 SUPERFAMILY SSF82866 622 798 1.83E-22 T 28-03-2018 hmeg3_RS16230 73cb11f45e9fbdb16c70ebdff2433999 810 SUPERFAMILY SSF82866 246 418 5.36E-19 T 28-03-2018 hmeg3_RS16230 73cb11f45e9fbdb16c70ebdff2433999 810 Pfam PF03176 MMPL family 61 423 4.5E-8 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 hmeg3_RS16230 73cb11f45e9fbdb16c70ebdff2433999 810 Gene3D G3DSA:1.20.1640.10 221 423 4.3E-19 T 28-03-2018 hmeg3_RS16230 73cb11f45e9fbdb16c70ebdff2433999 810 Gene3D G3DSA:1.20.1640.10 609 801 3.0E-20 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Pfam PF03797 Autotransporter beta-domain 1484 1736 9.0E-38 T 28-03-2018 IPR005546 Autotransporter beta-domain hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SUPERFAMILY SSF49313 471 542 4.08E-9 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.40.128.130 1360 1755 3.9E-46 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.500.10 904 993 1.5E-10 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.500.10 1175 1262 6.2E-9 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.500.10 1084 1174 6.4E-15 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.500.10 371 453 3.0E-11 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.500.10 635 724 9.5E-12 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.500.10 1263 1359 8.6E-10 T 28-03-2018 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SMART SM00869 1481 1746 5.0E-30 T 28-03-2018 IPR005546 Autotransporter beta-domain hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SUPERFAMILY SSF49313 732 814 7.06E-8 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SUPERFAMILY SSF49313 184 269 4.71E-7 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SUPERFAMILY SSF49313 993 1082 1.57E-5 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SUPERFAMILY SSF49313 545 621 4.76E-10 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 SUPERFAMILY SSF103515 1473 1755 1.44E-35 T 28-03-2018 IPR005546 Autotransporter beta-domain hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 170 267 6.8E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 725 814 1.4E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 268 365 9.7E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 454 540 3.4E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 815 902 2.3E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 541 631 3.9E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Gene3D G3DSA:2.60.40.10 994 1082 0.0016 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Pfam PF05345 Putative Ig domain 757 792 6.5E-8 T 28-03-2018 IPR008009 Putative Ig hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Pfam PF05345 Putative Ig domain 215 255 3.2E-5 T 28-03-2018 IPR008009 Putative Ig hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Pfam PF05345 Putative Ig domain 479 528 7.5E-5 T 28-03-2018 IPR008009 Putative Ig hmeg3_RS23655 0b701e28c8025e09d21f78da142fae7d 1758 Pfam PF05345 Putative Ig domain 576 618 2.4E-12 T 28-03-2018 IPR008009 Putative Ig hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 Pfam PF00072 Response regulator receiver domain 22 132 5.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 SUPERFAMILY SSF109604 205 376 6.98E-18 T 28-03-2018 hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 Pfam PF13487 HD domain 268 327 8.4E-17 T 28-03-2018 hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 Gene3D G3DSA:3.40.50.2300 12 184 1.8E-35 T 28-03-2018 hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 SUPERFAMILY SSF52172 18 185 2.7E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 SMART SM00448 20 132 1.4E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS03615 07c2166f34c5a0fecca1da601f7d2b46 449 Gene3D G3DSA:1.10.3210.10 194 402 2.2E-28 T 28-03-2018 hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 Pfam PF00072 Response regulator receiver domain 18 128 4.9E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 SUPERFAMILY SSF46894 145 246 3.68E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 Gene3D G3DSA:3.40.50.2300 2 140 1.0E-38 T 28-03-2018 hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 SMART SM00448 16 127 3.4E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 Gene3D G3DSA:1.10.10.10 141 249 8.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 SMART SM00862 168 244 4.7E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 SUPERFAMILY SSF52172 8 134 9.39E-42 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS09820 a6a6be21f28859253cf1e5a695fb205a 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 244 5.9E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82866 297 496 3.92E-49 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 1.1E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Gene3D G3DSA:1.20.1640.10 814 1026 8.0E-36 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82714 182 271 3.14E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Gene3D G3DSA:1.20.1640.10 287 510 3.0E-44 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Gene3D G3DSA:3.30.70.1430 568 666 1.3E-24 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Gene3D G3DSA:3.30.70.1440 670 766 4.2E-23 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82693 566 668 5.23E-33 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82693 38 131 8.89E-26 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82714 720 804 1.57E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1040 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82866 804 1026 8.76E-43 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Gene3D G3DSA:3.30.2090.10 180 275 2.5E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Gene3D G3DSA:3.30.70.1430 38 140 1.1E-27 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82693 135 182 1.92E-25 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 SUPERFAMILY SSF82693 274 330 1.92E-25 T 28-03-2018 hmeg3_RS21130 52ff8e9dbdb5c9f6d02145aadab4644d 1048 Pfam PF00873 AcrB/AcrD/AcrF family 2 1024 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03755 cbe60500ce467d04fdfdaa59e79ebb80 296 Gene3D G3DSA:3.40.630.30 12 145 1.8E-17 T 28-03-2018 hmeg3_RS03755 cbe60500ce467d04fdfdaa59e79ebb80 296 SUPERFAMILY SSF55729 16 275 8.49E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS03755 cbe60500ce467d04fdfdaa59e79ebb80 296 Gene3D G3DSA:3.40.630.30 146 224 7.3E-4 T 28-03-2018 hmeg3_RS03755 cbe60500ce467d04fdfdaa59e79ebb80 296 Pfam PF13673 Acetyltransferase (GNAT) domain 82 138 9.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 SUPERFAMILY SSF51120 1942 2062 7.72E-6 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1370 1434 1.6E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1308 1369 3.5E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1496 1562 1.4E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1045 1105 1.1E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 788 850 2.5E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1823 1890 3.1E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 2370 2448 5.8E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1435 1495 1.1E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 981 1044 3.0E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1757 1822 1.7E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 662 720 6.7E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 851 918 1.0E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1631 1691 6.8E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 721 787 2.6E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1956 2021 4.9E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1242 1307 5.6E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 599 661 1.1E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 2309 2369 1.7E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 2162 2235 7.5E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 533 598 5.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1173 1241 2.9E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 412 475 5.3E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1692 1756 2.7E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1106 1172 5.4E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 919 980 2.2E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 2022 2094 1.3E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 476 532 6.8E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 2236 2308 4.4E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1563 1630 1.9E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 2095 2161 7.1E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.60.120.10 1891 1955 1.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 SUPERFAMILY SSF51120 370 419 1.27E-9 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal hmeg3_RS07610 b02e26b31db1773bb8a4326a948fd5c6 2618 Gene3D G3DSA:2.150.10.10 183 411 7.3E-11 T 28-03-2018 hmeg3_RS14340 73982f87676f4bd54c46255ba647e613 259 SUPERFAMILY SSF53850 6 252 3.36E-65 T 28-03-2018 hmeg3_RS14340 73982f87676f4bd54c46255ba647e613 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 250 1.7E-59 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS14340 73982f87676f4bd54c46255ba647e613 259 Gene3D G3DSA:3.40.190.10 7 145 2.1E-33 T 28-03-2018 hmeg3_RS14340 73982f87676f4bd54c46255ba647e613 259 SMART SM00062 29 252 2.2E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS14340 73982f87676f4bd54c46255ba647e613 259 SMART SM00079 29 251 2.3E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS14340 73982f87676f4bd54c46255ba647e613 259 Gene3D G3DSA:3.40.190.10 146 251 9.7E-17 T 28-03-2018 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 Pfam PF03466 LysR substrate binding domain 96 297 9.3E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 Gene3D G3DSA:1.10.10.10 3 90 4.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 SUPERFAMILY SSF46785 8 110 2.49E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 SUPERFAMILY SSF53850 98 302 1.81E-31 T 28-03-2018 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 Gene3D G3DSA:3.40.190.10 189 274 1.9E-16 T 28-03-2018 hmeg3_RS19120 7634a4ba73c4989c5033eff5be5114cf 307 Gene3D G3DSA:3.40.190.10 97 188 7.2E-19 T 28-03-2018 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 Pfam PF10502 Signal peptidase, peptidase S26 251 290 9.8E-8 T 28-03-2018 IPR019533 Peptidase S26 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 Gene3D G3DSA:2.10.109.10 95 302 1.4E-55 T 28-03-2018 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 SUPERFAMILY SSF51306 97 299 6.28E-70 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 ProSitePatterns PS00501 Signal peptidases I serine active site. 108 115 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 Pfam PF00717 Peptidase S24-like 105 187 5.2E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 85 292 3.0E-52 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 ProSitePatterns PS00760 Signal peptidases I lysine active site. 165 177 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 163 175 3.5E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 253 272 3.5E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 99 115 3.5E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 hmeg3_RS16685 0a7ad14c38664746a8a0b449a7848d70 303 ProSitePatterns PS00761 Signal peptidases I signature 3. 258 271 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 SUPERFAMILY SSF51735 14 257 1.2E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 196 0.0079 T 28-03-2018 hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 Gene3D G3DSA:3.40.50.720 2 258 2.1E-67 T 28-03-2018 hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 4.1E-58 T 28-03-2018 hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 1.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00105 f373e2b18b1b9bd19d4b839f4c64a5b8 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 SUPERFAMILY SSF55681 171 515 4.98E-114 T 28-03-2018 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 Pfam PF00152 tRNA synthetases class II (D, K and N) 171 514 5.6E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 SUPERFAMILY SSF50249 18 164 4.9E-40 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 Gene3D G3DSA:2.40.50.140 20 164 5.1E-36 T 28-03-2018 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 26 517 43.23 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 Gene3D G3DSA:3.30.930.10 165 514 4.1E-97 T 28-03-2018 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 Pfam PF01336 OB-fold nucleic acid binding domain 73 155 4.4E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 253 266 8.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 399 415 8.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 271 288 8.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 224 240 8.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 208 218 8.4E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS09165 b492472886d15e5b110d7c17b7599a14 518 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 21 516 1.8E-194 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS03360 e8d28452c2a905ac3c4cbaf0415440a4 463 Pfam PF00675 Insulinase (Peptidase family M16) 45 189 4.6E-30 T 28-03-2018 IPR011765 Peptidase M16, N-terminal hmeg3_RS03360 e8d28452c2a905ac3c4cbaf0415440a4 463 Pfam PF05193 Peptidase M16 inactive domain 199 381 2.0E-32 T 28-03-2018 IPR007863 Peptidase M16, C-terminal hmeg3_RS03360 e8d28452c2a905ac3c4cbaf0415440a4 463 Gene3D G3DSA:3.30.830.10 31 252 3.8E-68 T 28-03-2018 hmeg3_RS03360 e8d28452c2a905ac3c4cbaf0415440a4 463 Gene3D G3DSA:3.30.830.10 259 449 1.8E-41 T 28-03-2018 hmeg3_RS03360 e8d28452c2a905ac3c4cbaf0415440a4 463 SUPERFAMILY SSF63411 255 448 2.55E-37 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS03360 e8d28452c2a905ac3c4cbaf0415440a4 463 SUPERFAMILY SSF63411 37 244 2.17E-62 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 Pfam PF02254 TrkA-N domain 417 530 1.5E-19 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 Pfam PF00999 Sodium/hydrogen exchanger family 10 381 1.9E-68 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 Gene3D G3DSA:1.20.91.10 236 316 1.0E-11 T 28-03-2018 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 Gene3D G3DSA:3.30.70.1450 579 662 3.3E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 Pfam PF02080 TrkA-C domain 593 659 1.4E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 Gene3D G3DSA:3.40.50.720 406 531 5.5E-19 T 28-03-2018 hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 SUPERFAMILY SSF51735 414 554 1.26E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04055 622dcbd277a1a1f31ef728c6782b5767 662 SUPERFAMILY SSF116726 579 657 5.75E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Pfam PF01568 Molydopterin dinucleotide binding domain 693 759 1.4E-5 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 626 4.1E-210 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Gene3D G3DSA:2.20.25.90 209 274 5.3E-4 T 28-03-2018 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 SUPERFAMILY SSF54292 1 74 5.04E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Gene3D G3DSA:3.40.50.740 275 674 1.7E-55 T 28-03-2018 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 SUPERFAMILY SSF50692 689 758 7.25E-6 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 SMART SM00929 83 123 1.5E-20 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 SUPERFAMILY SSF53706 214 650 5.63E-91 T 28-03-2018 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Pfam PF00384 Molybdopterin oxidoreductase 273 626 6.2E-34 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 119 1.9E-16 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Gene3D G3DSA:2.40.40.20 691 771 3.7E-8 T 28-03-2018 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 SUPERFAMILY SSF54862 76 211 1.46E-37 T 28-03-2018 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Gene3D G3DSA:3.10.20.30 1 162 7.1E-16 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13755 283bb08190b722c179193d14d5295d5a 775 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 75 5.7E-19 T 28-03-2018 hmeg3_RS08795 ff1b3bd67e1f61a2f0a076131e30d4d3 365 SUPERFAMILY SSF52540 48 179 8.61E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08795 ff1b3bd67e1f61a2f0a076131e30d4d3 365 Gene3D G3DSA:3.40.50.300 18 355 3.9E-15 T 28-03-2018 hmeg3_RS08795 ff1b3bd67e1f61a2f0a076131e30d4d3 365 Pfam PF03969 AFG1-like ATPase 3 354 1.9E-125 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 hmeg3_RS17820 242040146be187e099416da379ec4273 556 SUPERFAMILY SSF52016 379 555 4.08E-56 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS17820 242040146be187e099416da379ec4273 556 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17820 242040146be187e099416da379ec4273 556 SUPERFAMILY SSF143975 3 377 3.92E-135 T 28-03-2018 hmeg3_RS17820 242040146be187e099416da379ec4273 556 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 464 475 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17820 242040146be187e099416da379ec4273 556 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 555 3.2E-229 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17820 242040146be187e099416da379ec4273 556 Pfam PF00920 Dehydratase family 35 553 3.4E-207 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17820 242040146be187e099416da379ec4273 556 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 556 44.167 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS00415 73c3dc3752615c294bc66efff479147f 438 SUPERFAMILY SSF53850 29 429 1.96E-56 T 28-03-2018 hmeg3_RS00415 73c3dc3752615c294bc66efff479147f 438 Gene3D G3DSA:3.40.190.10 155 434 3.7E-37 T 28-03-2018 hmeg3_RS00415 73c3dc3752615c294bc66efff479147f 438 Gene3D G3DSA:3.20.20.70 58 149 0.17 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS00415 73c3dc3752615c294bc66efff479147f 438 Pfam PF13416 Bacterial extracellular solute-binding protein 63 345 8.8E-31 T 28-03-2018 hmeg3_RS03370 29658ea54d82b76c373a8fd4fac8e028 438 Gene3D G3DSA:3.30.830.10 24 245 3.8E-32 T 28-03-2018 hmeg3_RS03370 29658ea54d82b76c373a8fd4fac8e028 438 SUPERFAMILY SSF63411 252 435 1.65E-42 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS03370 29658ea54d82b76c373a8fd4fac8e028 438 Pfam PF05193 Peptidase M16 inactive domain 195 370 1.9E-29 T 28-03-2018 IPR007863 Peptidase M16, C-terminal hmeg3_RS03370 29658ea54d82b76c373a8fd4fac8e028 438 SUPERFAMILY SSF63411 22 244 1.83E-32 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 hmeg3_RS03370 29658ea54d82b76c373a8fd4fac8e028 438 Gene3D G3DSA:3.30.830.10 254 438 7.1E-37 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82714 726 814 5.23E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82714 193 275 5.36E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Gene3D G3DSA:3.30.70.1430 42 135 1.4E-23 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Gene3D G3DSA:1.20.1640.10 818 1037 3.3E-38 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82693 42 127 1.49E-22 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Gene3D G3DSA:3.30.70.1430 568 670 6.3E-13 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82866 299 506 9.81E-35 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Gene3D G3DSA:3.30.2090.10 725 817 2.1E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Gene3D G3DSA:3.30.2090.10 190 277 5.6E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Pfam PF00873 AcrB/AcrD/AcrF family 5 1036 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1041 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82693 155 191 2.44E-20 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82693 277 333 2.44E-20 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.8E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.8E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.8E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 1.8E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.8E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82866 813 1036 2.75E-56 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 Gene3D G3DSA:1.20.1640.10 293 520 1.3E-35 T 28-03-2018 hmeg3_RS19070 17fd0577a67f0c843aa538a435abe9a9 1071 SUPERFAMILY SSF82693 575 667 1.1E-5 T 28-03-2018 hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 Gene3D G3DSA:3.40.50.720 48 249 1.1E-60 T 28-03-2018 hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 Gene3D G3DSA:3.40.50.720 1 47 3.7E-7 T 28-03-2018 hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 1.3E-66 T 28-03-2018 hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS21580 df2f4b0de82d4c7c5ec0628b8c66fab2 249 SUPERFAMILY SSF51735 4 248 1.82E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 Pfam PF08281 Sigma-70, region 4 112 163 6.9E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 Pfam PF04542 Sigma-70 region 2 18 76 1.6E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 SUPERFAMILY SSF88946 12 75 3.53E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 SUPERFAMILY SSF88659 95 167 2.06E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 Gene3D G3DSA:1.10.1740.10 4 81 5.9E-11 T 28-03-2018 hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 Gene3D G3DSA:1.10.10.10 90 167 6.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11630 7c098ce132b8da86368c8a3aaf8ec594 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 165 4.4E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 495 8.5E-228 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 251 1.0E-85 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 SUPERFAMILY SSF53067 253 495 1.64E-85 T 28-03-2018 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 Hamap MF_00186 Glycerol kinase [glpK]. 3 496 59.058 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 Gene3D G3DSA:3.30.420.40 248 499 4.5E-80 T 28-03-2018 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 Gene3D G3DSA:3.30.420.40 1 247 7.8E-93 T 28-03-2018 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 SUPERFAMILY SSF53067 5 254 3.2E-98 T 28-03-2018 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 PIRSF PIRSF000538 3 499 1.0E-184 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 hmeg3_RS22465 3801c456a2f91f57b0c7c40740016b06 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 449 7.0E-62 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 84 5.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 SUPERFAMILY SSF48008 93 223 2.88E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 Pfam PF07729 FCD domain 98 216 4.5E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 SMART SM00895 94 218 2.0E-16 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 SUPERFAMILY SSF46785 16 88 3.04E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 SMART SM00345 26 84 3.8E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 Gene3D G3DSA:1.10.10.10 10 86 4.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13235 c01f85df4216135dde156a3f4bcb37ad 236 Gene3D G3DSA:1.20.120.530 87 236 1.8E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 SUPERFAMILY SSF55073 345 505 1.02E-43 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 Gene3D G3DSA:3.30.450.20 169 285 7.2E-15 T 28-03-2018 hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 Pfam PF00990 Diguanylate cyclase, GGDEF domain 340 501 1.6E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 Gene3D G3DSA:3.30.70.270 333 510 1.3E-52 T 28-03-2018 hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 336 503 7.8E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 Pfam PF02743 Cache domain 41 264 7.0E-22 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 Gene3D G3DSA:3.30.450.20 35 168 5.8E-19 T 28-03-2018 hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 SMART SM00267 329 505 1.3E-54 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11500 10958e49ee13ccb0939275a87fa49fff 515 SUPERFAMILY SSF103190 101 193 4.32E-5 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 SUPERFAMILY SSF64288 82 260 8.95E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 SUPERFAMILY SSF46785 28 97 2.12E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 Gene3D G3DSA:1.10.10.10 23 95 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 93 9.4E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 5.6E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 5.6E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 SMART SM00866 113 255 3.7E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 SMART SM00345 34 93 1.1E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 Pfam PF07702 UTRA domain 116 250 3.6E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 hmeg3_RS08745 7848e35515948c22dd028e70231ce446 261 Gene3D G3DSA:3.40.1410.10 101 260 2.9E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain hmeg3_RS12675 1942c744ef0288823638ca96b71c22cb 238 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 8 228 7.3E-63 T 28-03-2018 hmeg3_RS12675 1942c744ef0288823638ca96b71c22cb 238 SUPERFAMILY SSF52096 24 199 2.17E-18 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS12675 1942c744ef0288823638ca96b71c22cb 238 Gene3D G3DSA:3.90.226.10 3 216 4.6E-16 T 28-03-2018 hmeg3_RS12675 1942c744ef0288823638ca96b71c22cb 238 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 3 230 1.6E-75 T 28-03-2018 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 PIRSF PIRSF000097 1 267 3.1E-70 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 115 132 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 PRINTS PR00069 Aldo-keto reductase signature 187 211 3.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 PRINTS PR00069 Aldo-keto reductase signature 115 132 3.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 PRINTS PR00069 Aldo-keto reductase signature 82 100 3.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 PRINTS PR00069 Aldo-keto reductase signature 26 50 3.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 PRINTS PR00069 Aldo-keto reductase signature 150 179 3.6E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 SUPERFAMILY SSF51430 3 262 2.62E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 30 47 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 Gene3D G3DSA:3.20.20.100 1 265 3.0E-83 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS18475 b550212e4caed610b19d6f4ca0d655fc 267 Pfam PF00248 Aldo/keto reductase family 8 251 1.0E-46 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS20570 a577c4947ccfa3b29afc322db3d0c8c6 366 Gene3D G3DSA:3.40.50.1820 55 366 3.2E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20570 a577c4947ccfa3b29afc322db3d0c8c6 366 Pfam PF01738 Dienelactone hydrolase family 83 196 4.0E-9 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS20570 a577c4947ccfa3b29afc322db3d0c8c6 366 SUPERFAMILY SSF53474 60 202 2.16E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20570 a577c4947ccfa3b29afc322db3d0c8c6 366 SUPERFAMILY SSF53474 258 358 2.16E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05570 f72002324096e32cb5b50abbc50046da 332 SUPERFAMILY SSF46785 1 86 1.06E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05570 f72002324096e32cb5b50abbc50046da 332 Gene3D G3DSA:1.10.10.10 85 180 1.6E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05570 f72002324096e32cb5b50abbc50046da 332 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 173 2.6E-46 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 hmeg3_RS05570 f72002324096e32cb5b50abbc50046da 332 SUPERFAMILY SSF46785 89 164 6.34E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05570 f72002324096e32cb5b50abbc50046da 332 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 180 1.7E-32 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 hmeg3_RS05570 f72002324096e32cb5b50abbc50046da 332 Gene3D G3DSA:1.10.10.10 5 82 3.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 727 2.0E-14 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 665 2.0E-14 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 364 378 2.0E-14 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 526 2.0E-14 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Pfam PF00403 Heavy-metal-associated domain 99 158 8.9E-11 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 ProSitePatterns PS01229 Hypothetical cof family signature 2. 708 730 - T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 514 520 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Gene3D G3DSA:3.40.1110.10 533 672 8.1E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Gene3D G3DSA:3.40.1110.10 673 722 0.1 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 SUPERFAMILY SSF55008 91 164 1.57E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Pfam PF00702 haloacid dehalogenase-like hydrolase 510 722 4.4E-32 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 SUPERFAMILY SSF56784 567 808 6.95E-42 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 SUPERFAMILY SSF56784 511 530 6.95E-42 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 284 790 9.5E-68 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 SUPERFAMILY SSF81653 326 413 5.23E-19 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 12 86 1.3E-18 T 28-03-2018 IPR021993 Putative metal-binding domain of cation transport ATPase hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 250 810 4.5E-150 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Pfam PF00122 E1-E2 ATPase 328 492 5.8E-44 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 SUPERFAMILY SSF81665 415 505 6.8E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 SUPERFAMILY SSF81665 258 315 6.8E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 232 810 7.0E-132 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Gene3D G3DSA:3.30.70.100 95 164 1.2E-14 T 28-03-2018 hmeg3_RS11580 537c33b59bd2204d3c8f7f2d07b83efe 820 Gene3D G3DSA:1.20.1110.10 254 532 3.4E-30 T 28-03-2018 hmeg3_RS02500 624cd272720690ddb883526f1b0e5eff 214 SUPERFAMILY SSF110997 136 212 5.75E-18 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS02500 624cd272720690ddb883526f1b0e5eff 214 Gene3D G3DSA:3.30.70.1070 133 212 2.7E-17 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS02500 624cd272720690ddb883526f1b0e5eff 214 Pfam PF05036 Sporulation related domain 139 211 2.2E-17 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS01435 66759d8e92f2ad1f5652fa65579929c4 219 SUPERFAMILY SSF52833 47 217 2.58E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS01435 66759d8e92f2ad1f5652fa65579929c4 219 Pfam PF00578 AhpC/TSA family 51 196 2.9E-32 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS01435 66759d8e92f2ad1f5652fa65579929c4 219 Gene3D G3DSA:3.40.30.10 34 218 5.1E-36 T 28-03-2018 hmeg3_RS16090 d607777717ec1b38d53840b1d8b1131d 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 3.7E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS16090 d607777717ec1b38d53840b1d8b1131d 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 206 8.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS16090 d607777717ec1b38d53840b1d8b1131d 232 Gene3D G3DSA:1.10.3720.10 2 221 1.8E-32 T 28-03-2018 hmeg3_RS16090 d607777717ec1b38d53840b1d8b1131d 232 SUPERFAMILY SSF161098 16 207 2.22E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 Pfam PF00005 ABC transporter 24 165 8.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 Gene3D G3DSA:2.40.50.100 244 292 2.3E-10 T 28-03-2018 hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 SUPERFAMILY SSF50331 240 355 4.13E-27 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 Gene3D G3DSA:2.40.50.140 293 340 3.0E-14 T 28-03-2018 hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 SMART SM00382 32 215 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 SUPERFAMILY SSF52540 4 246 6.01E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 Gene3D G3DSA:3.40.50.300 1 243 2.9E-66 T 28-03-2018 hmeg3_RS04965 77e9a39dbb50cb987ab10eb77010db1e 356 Pfam PF08402 TOBE domain 280 347 6.6E-10 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 SUPERFAMILY SSF51735 14 257 4.48E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 4.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 4.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 4.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 257 5.4E-54 T 28-03-2018 hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18980 a5541f6428fad27e3b0c3f02a06d6f34 258 Gene3D G3DSA:3.40.50.720 5 258 2.3E-58 T 28-03-2018 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 SMART SM00304 177 229 9.8E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 Pfam PF00672 HAMP domain 177 224 2.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 Gene3D G3DSA:3.30.565.10 297 439 2.3E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 Gene3D G3DSA:1.10.287.130 220 296 5.0E-8 T 28-03-2018 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 SMART SM00387 328 439 1.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 SUPERFAMILY SSF55874 311 435 1.96E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 5.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 392 5.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 5.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 SMART SM00388 230 288 4.7E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 435 9.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06305 54cb7c5a879c9f7cba2567f448060702 439 SUPERFAMILY SSF47384 215 284 4.51E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Gene3D G3DSA:3.40.50.300 1 279 3.1E-56 T 28-03-2018 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SMART SM00838 606 695 1.2E-54 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Gene3D G3DSA:3.30.70.870 402 498 7.0E-38 T 28-03-2018 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SUPERFAMILY SSF54980 409 486 5.76E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SMART SM00889 485 604 1.5E-74 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SUPERFAMILY SSF54211 484 605 1.92E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Pfam PF03764 Elongation factor G, domain IV 484 604 1.0E-46 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 110.228 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Gene3D G3DSA:2.40.30.10 280 400 1.9E-28 T 28-03-2018 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 187 6.4E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Pfam PF14492 Elongation Factor G, domain II 409 483 3.7E-35 T 28-03-2018 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Pfam PF03144 Elongation factor Tu domain 2 329 396 9.3E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 700 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Gene3D G3DSA:3.30.70.240 615 694 3.2E-32 T 28-03-2018 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SUPERFAMILY SSF50447 271 407 2.1E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SUPERFAMILY SSF54980 609 698 3.6E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Pfam PF00679 Elongation factor G C-terminus 606 694 6.4E-32 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 SUPERFAMILY SSF52540 7 288 7.19E-105 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.7E-65 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 PRINTS PR00315 GTP-binding elongation factor signature 137 146 5.6E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.6E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.6E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 PRINTS PR00315 GTP-binding elongation factor signature 85 95 5.6E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 PRINTS PR00315 GTP-binding elongation factor signature 101 112 5.6E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS02620 e1b387fd87dfd6e250603dced3b6314c 702 Gene3D G3DSA:3.30.230.10 499 614 3.3E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS02290 2f06a80222ec42d5a9ac40d612cd1334 278 Gene3D G3DSA:3.40.190.10 120 262 2.1E-18 T 28-03-2018 hmeg3_RS02290 2f06a80222ec42d5a9ac40d612cd1334 278 Gene3D G3DSA:3.40.190.10 36 119 6.4E-5 T 28-03-2018 hmeg3_RS02290 2f06a80222ec42d5a9ac40d612cd1334 278 SUPERFAMILY SSF53850 21 250 1.39E-28 T 28-03-2018 hmeg3_RS02290 2f06a80222ec42d5a9ac40d612cd1334 278 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 45 265 1.7E-48 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF55785 775 899 9.07E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 583 7.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1025 1134 9.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SMART SM00387 1024 1137 1.3E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SMART SM00387 474 585 1.6E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.30.565.10 962 1136 8.9E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF00512 His Kinase A (phospho-acceptor) domain 915 977 1.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF00512 His Kinase A (phospho-acceptor) domain 361 428 4.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF55874 417 583 1.44E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.30.450.20 41 167 5.9E-6 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.30.565.10 433 592 1.5E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF55781 268 351 1.18E-8 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:1.10.287.130 910 961 1.8E-15 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:1.10.287.130 359 424 1.1E-16 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SMART SM00448 652 764 6.2E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SMART SM00448 1162 1275 3.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF55874 967 1139 3.8E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 524 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 582 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 563 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 538 1.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF52172 1162 1283 3.98E-30 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.40.50.2300 635 775 1.5E-34 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.40.50.2300 1160 1303 1.5E-29 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF52172 647 774 5.27E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SMART SM00388 360 428 7.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SMART SM00388 914 978 4.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF47384 899 979 1.53E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 SUPERFAMILY SSF47384 344 429 1.63E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.30.450.20 776 909 1.3E-13 T 28-03-2018 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Gene3D G3DSA:3.30.450.40 168 358 1.7E-15 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF08448 PAS fold 788 902 3.4E-7 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF08448 PAS fold 69 162 5.4E-5 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF00072 Response regulator receiver domain 1164 1274 3.3E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12135 87647de6aa641d5d390040bad045846c 1307 Pfam PF00072 Response regulator receiver domain 654 765 1.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14185 43b7c2daf020fe37f8ad3cddb5923359 526 Gene3D G3DSA:3.40.190.10 164 306 3.8E-25 T 28-03-2018 hmeg3_RS14185 43b7c2daf020fe37f8ad3cddb5923359 526 Gene3D G3DSA:3.10.105.10 307 497 1.5E-26 T 28-03-2018 hmeg3_RS14185 43b7c2daf020fe37f8ad3cddb5923359 526 PIRSF PIRSF002741 10 525 2.1E-65 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS14185 43b7c2daf020fe37f8ad3cddb5923359 526 SUPERFAMILY SSF53850 41 521 9.41E-99 T 28-03-2018 hmeg3_RS14185 43b7c2daf020fe37f8ad3cddb5923359 526 Gene3D G3DSA:3.90.76.10 69 163 4.3E-25 T 28-03-2018 hmeg3_RS14185 43b7c2daf020fe37f8ad3cddb5923359 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 441 5.2E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS22710 db3976beb18a20f4d58a1a4c7700b0e2 110 Gene3D G3DSA:3.30.70.120 2 108 1.8E-41 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal hmeg3_RS22710 db3976beb18a20f4d58a1a4c7700b0e2 110 Pfam PF03091 CutA1 divalent ion tolerance protein 6 102 1.7E-37 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 hmeg3_RS22710 db3976beb18a20f4d58a1a4c7700b0e2 110 SUPERFAMILY SSF54913 2 105 1.74E-38 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 Pfam PF03705 CheR methyltransferase, all-alpha domain 16 65 1.5E-9 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 SUPERFAMILY SSF53335 82 272 8.59E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 Pfam PF01739 CheR methyltransferase, SAM binding domain 82 266 5.2E-52 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 SMART SM00138 14 275 1.3E-75 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 Gene3D G3DSA:1.10.155.10 6 80 1.9E-15 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PIRSF PIRSF000410 1 275 4.2E-88 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 SUPERFAMILY SSF47757 10 81 1.06E-14 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 Gene3D G3DSA:3.40.50.150 81 275 1.4E-45 T 28-03-2018 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PRINTS PR00996 Glutamate methyltransferase family signature 75 87 3.1E-36 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 3.1E-36 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PRINTS PR00996 Glutamate methyltransferase family signature 111 131 3.1E-36 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PRINTS PR00996 Glutamate methyltransferase family signature 36 49 3.1E-36 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PRINTS PR00996 Glutamate methyltransferase family signature 215 229 3.1E-36 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS20320 705802f4187f175fee93276744cadbac 276 PRINTS PR00996 Glutamate methyltransferase family signature 234 257 3.1E-36 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 SUPERFAMILY SSF53383 376 516 4.08E-43 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 SUPERFAMILY SSF53383 124 342 4.08E-43 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 Gene3D G3DSA:3.90.1150.10 378 520 8.6E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 Gene3D G3DSA:3.40.640.10 155 377 9.1E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 309 322 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 Pfam PF00155 Aminotransferase class I and II 189 508 8.5E-27 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS11990 72ca33d32b90bd7a958a4ecd10fe7b05 551 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 12 520 2.0E-240 T 28-03-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 216 570 43.066 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 SUPERFAMILY SSF56796 218 568 2.09E-117 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Gene3D G3DSA:3.40.50.1970 219 386 4.3E-54 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Pfam PF01761 3-dehydroquinate synthase 281 538 8.8E-109 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 SUPERFAMILY SSF52540 5 167 2.23E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 PRINTS PR01100 Shikimate kinase family signature 96 113 4.4E-24 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 PRINTS PR01100 Shikimate kinase family signature 5 20 4.4E-24 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 PRINTS PR01100 Shikimate kinase family signature 29 42 4.4E-24 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 PRINTS PR01100 Shikimate kinase family signature 57 65 4.4E-24 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 PRINTS PR01100 Shikimate kinase family signature 75 84 4.4E-24 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 227 566 8.1E-121 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Pfam PF01202 Shikimate kinase 11 167 4.4E-53 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Gene3D G3DSA:3.40.50.300 1 181 1.9E-30 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Gene3D G3DSA:1.20.1090.10 387 574 1.8E-67 T 28-03-2018 hmeg3_RS03175 8664ee968dc3816b841254a992f7e0cc 574 Hamap MF_00109 Shikimate kinase [aroK]. 2 168 30.427 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 hmeg3_RS06390 2ccf4556e4a85ab2d34ca7d7573d51a6 143 Pfam PF01047 MarR family 37 95 3.5E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06390 2ccf4556e4a85ab2d34ca7d7573d51a6 143 SUPERFAMILY SSF46785 5 142 1.94E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06390 2ccf4556e4a85ab2d34ca7d7573d51a6 143 SMART SM00347 30 140 1.3E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06390 2ccf4556e4a85ab2d34ca7d7573d51a6 143 Gene3D G3DSA:1.10.10.10 8 143 3.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03880 f0774379905abf15a1ea36a600c73196 281 SUPERFAMILY SSF52540 20 260 4.99E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03880 f0774379905abf15a1ea36a600c73196 281 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03880 f0774379905abf15a1ea36a600c73196 281 Pfam PF00005 ABC transporter 42 190 1.4E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03880 f0774379905abf15a1ea36a600c73196 281 SMART SM00382 50 239 1.1E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03880 f0774379905abf15a1ea36a600c73196 281 Gene3D G3DSA:3.40.50.300 13 272 2.3E-74 T 28-03-2018 hmeg3_RS05080 06e8a71b8ea323d62943e8c94f4565a9 291 SUPERFAMILY SSF69572 18 287 4.45E-61 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 hmeg3_RS05080 06e8a71b8ea323d62943e8c94f4565a9 291 Pfam PF00899 ThiF family 28 173 5.2E-35 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 hmeg3_RS05080 06e8a71b8ea323d62943e8c94f4565a9 291 Gene3D G3DSA:3.40.50.720 13 290 5.6E-51 T 28-03-2018 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 PIRSF PIRSF003095 1 448 5.0E-120 T 28-03-2018 IPR005215 Trigger factor GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Gene3D G3DSA:1.10.3120.10 239 403 4.7E-45 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 SUPERFAMILY SSF109998 260 443 3.66E-48 T 28-03-2018 IPR027304 Trigger factor/SurA domain hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 TIGRFAM TIGR00115 tig: trigger factor 11 426 3.0E-127 T 28-03-2018 IPR005215 Trigger factor GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 SUPERFAMILY SSF54534 97 252 1.1E-28 T 28-03-2018 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Gene3D G3DSA:3.10.50.40 139 238 8.2E-12 T 28-03-2018 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Gene3D G3DSA:3.30.70.1050 1 120 1.6E-28 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 275 426 1.6E-35 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Hamap MF_00303 Trigger factor [tig]. 1 432 20.357 T 28-03-2018 IPR005215 Trigger factor GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 SUPERFAMILY SSF102735 1 130 4.19E-32 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 169 249 1.9E-13 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain hmeg3_RS10445 1db2617e4bfc03f60387a5c8ecf3b6ad 448 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 8.8E-35 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 hmeg3_RS14240 71754138fad2dce9a27b217047160089 211 Gene3D G3DSA:2.30.110.10 1 210 2.7E-64 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS14240 71754138fad2dce9a27b217047160089 211 PIRSF PIRSF010372 1 211 5.5E-76 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type hmeg3_RS14240 71754138fad2dce9a27b217047160089 211 SUPERFAMILY SSF50475 9 193 6.73E-38 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS14240 71754138fad2dce9a27b217047160089 211 Pfam PF04299 Putative FMN-binding domain 2 168 9.7E-65 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 Gene3D G3DSA:1.10.220.30 70 189 8.7E-20 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 Gene3D G3DSA:1.10.220.30 193 331 7.4E-31 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PIRSF PIRSF003161 1 331 3.0E-117 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 328 6.6E-110 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 SUPERFAMILY SSF48029 2 114 6.54E-23 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 112 135 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 246 266 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 32 58 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 270 296 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 3 19 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 193 218 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 224 244 1.6E-65 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 Pfam PF01706 FliG C-terminal domain 216 322 2.7E-40 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 Pfam PF14842 FliG N-terminal domain 5 101 2.4E-29 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 Gene3D G3DSA:1.10.220.30 1 67 9.8E-9 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 SUPERFAMILY SSF48029 112 322 1.2E-65 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical hmeg3_RS08315 592f97aff517ca5735d6b9d6fd9f84b2 331 Pfam PF14841 FliG middle domain 114 186 2.2E-25 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 Gene3D G3DSA:2.40.110.10 120 220 4.5E-39 T 28-03-2018 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 Gene3D G3DSA:1.10.540.10 2 119 2.9E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 SUPERFAMILY SSF56645 9 242 7.46E-75 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 378 1.4E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 217 7.9E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 117 2.6E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 SUPERFAMILY SSF47203 227 381 3.06E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 Gene3D G3DSA:1.20.140.10 221 385 1.5E-58 T 28-03-2018 hmeg3_RS20930 ffdf6dc6197a7983926f42da93e0d18e 385 PIRSF PIRSF016578 2 383 6.4E-20 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:1.10.1200.10 603 690 1.9E-14 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:1.10.1200.10 1688 1754 1.6E-17 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:2.30.38.10 3019 3100 3.1E-24 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:2.30.38.10 1480 1560 7.9E-22 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 896 1141 4.11E-42 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.40.50.980 1158 1317 5.0E-38 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF47336 3209 3283 1.7E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF56801 2693 3230 6.8E-162 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:1.10.1200.10 3221 3279 1.7E-17 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 2251 2419 3.56E-38 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1706 1721 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.559.10 1755 1954 5.9E-29 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:2.30.38.10 359 452 3.0E-18 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 1949 2209 2.78E-32 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF13193 AMP-binding enzyme C-terminal domain 1578 1651 6.7E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF13193 AMP-binding enzyme C-terminal domain 3118 3192 3.2E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1312 1323 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00668 Condensation domain 3305 3750 2.3E-107 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00668 Condensation domain 710 1144 1.7E-73 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00668 Condensation domain 1768 2210 3.3E-59 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00668 Condensation domain 2246 2682 4.8E-82 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 2420 2666 2.22E-49 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2078 2231 3.2E-41 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 ProSitePatterns PS00012 Phosphopantetheine attachment site. 636 651 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.40.50.980 178 350 2.2E-39 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.40.50.980 2858 3018 1.5E-41 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.40.50.980 1318 1479 5.8E-33 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 3310 3490 7.23E-46 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF56801 1161 1695 3.4E-133 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00501 AMP-binding enzyme 19 461 9.4E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00501 AMP-binding enzyme 2713 3110 7.7E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00501 AMP-binding enzyme 1167 1570 3.6E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.60.130.10 3803 4121 1.4E-64 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF56801 15 575 6.93E-106 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.40.50.980 2695 2857 2.2E-44 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.40.50.980 9 177 5.9E-30 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 715 888 3.11E-42 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.300.30 453 566 6.3E-13 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2853 2864 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 1768 1937 7.23E-31 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF47336 1677 1743 1.83E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2725 3134 1.7E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1189 1593 1.2E-105 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00550 Phosphopantetheine attachment site 611 677 7.6E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00550 Phosphopantetheine attachment site 3218 3283 3.5E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF00550 Phosphopantetheine attachment site 1685 1743 1.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.559.10 2225 2431 6.0E-35 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.559.10 691 913 1.5E-37 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.559.10 3280 3514 8.1E-42 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF47336 606 709 4.19E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF51197 3807 4119 9.16E-80 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 3825 4118 2.1E-47 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.300.30 3105 3220 3.0E-36 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 Gene3D G3DSA:3.30.300.30 1565 1687 1.5E-35 T 28-03-2018 hmeg3_RS11650 4e29d18f9a8d6d669179e335dbb54c1a 4149 SUPERFAMILY SSF52777 3497 3740 1.45E-54 T 28-03-2018 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 SUPERFAMILY SSF52540 144 382 8.74E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Pfam PF02954 Bacterial regulatory protein, Fis family 409 446 1.6E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Gene3D G3DSA:3.40.50.2300 1 140 1.9E-30 T 28-03-2018 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Gene3D G3DSA:3.40.50.300 141 316 2.7E-27 T 28-03-2018 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 412 429 7.8E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 449 7.8E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 SMART SM00448 2 112 1.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 SUPERFAMILY SSF46689 354 448 4.35E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Gene3D G3DSA:1.10.8.60 317 386 3.8E-21 T 28-03-2018 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Pfam PF00158 Sigma-54 interaction domain 145 310 7.1E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 SUPERFAMILY SSF52172 1 189 1.85E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 SMART SM00382 164 307 7.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01725 5155f90a411ff8ab82e4792609016d7e 449 Gene3D G3DSA:1.10.10.60 392 449 2.5E-16 T 28-03-2018 hmeg3_RS13875 0b38a18b5617bd41897b09a04c987899 127 SUPERFAMILY SSF55298 17 126 1.12E-34 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS13875 0b38a18b5617bd41897b09a04c987899 127 Gene3D G3DSA:3.30.1330.40 16 127 2.8E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS13875 0b38a18b5617bd41897b09a04c987899 127 Pfam PF01042 Endoribonuclease L-PSP 20 124 8.2E-26 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 SMART SM00382 244 394 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Pfam PF06506 Propionate catabolism activator 37 202 1.1E-49 T 28-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Gene3D G3DSA:1.20.5.170 181 222 1.1E-21 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Gene3D G3DSA:1.10.8.60 404 480 6.1E-16 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Gene3D G3DSA:3.40.50.300 223 403 5.4E-26 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Pfam PF02954 Bacterial regulatory protein, Fis family 514 544 4.9E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 448 457 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 SUPERFAMILY SSF159800 15 198 3.92E-53 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 512 529 6.5E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 529 547 6.5E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Gene3D G3DSA:1.10.10.60 495 544 4.8E-11 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 SUPERFAMILY SSF46689 448 544 5.08E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Gene3D G3DSA:3.40.50.10660 100 180 9.0E-25 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Gene3D G3DSA:3.40.50.2300 3 99 7.3E-24 T 28-03-2018 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 SUPERFAMILY SSF52540 224 469 1.15E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 Pfam PF00158 Sigma-54 interaction domain 225 397 2.0E-64 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS15445 d5a46cc233d4a75f418d06ae923377bc 547 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 12 543 6.5E-244 T 28-03-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 Gene3D G3DSA:3.90.170.10 272 437 2.6E-68 T 28-03-2018 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 138 149 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 16 23 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 437 210.797 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 SMART SM00788 9 431 1.8E-288 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 11 436 5.0E-177 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 Pfam PF00709 Adenylosuccinate synthetase 10 430 4.0E-175 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 Gene3D G3DSA:3.40.440.10 6 160 1.2E-52 T 28-03-2018 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 Gene3D G3DSA:3.40.440.10 161 271 1.9E-22 T 28-03-2018 hmeg3_RS08920 e977e47d1195538b7383d6286c4dd9d6 437 SUPERFAMILY SSF52540 8 436 1.27E-171 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11105 72fcd0293ec1169731a09ec1c77b2f87 525 PIRSF PIRSF002741 7 524 3.6E-100 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS11105 72fcd0293ec1169731a09ec1c77b2f87 525 Gene3D G3DSA:3.10.105.10 297 496 3.2E-50 T 28-03-2018 hmeg3_RS11105 72fcd0293ec1169731a09ec1c77b2f87 525 Gene3D G3DSA:3.40.190.10 150 296 9.7E-37 T 28-03-2018 hmeg3_RS11105 72fcd0293ec1169731a09ec1c77b2f87 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 435 2.5E-86 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS11105 72fcd0293ec1169731a09ec1c77b2f87 525 Gene3D G3DSA:3.90.76.10 26 149 8.6E-25 T 28-03-2018 hmeg3_RS11105 72fcd0293ec1169731a09ec1c77b2f87 525 SUPERFAMILY SSF53850 24 506 1.38E-122 T 28-03-2018 hmeg3_RS19360 3b53f96b111e5216c15f8dcb285a704f 278 Gene3D G3DSA:3.40.830.10 1 278 5.6E-54 T 28-03-2018 hmeg3_RS19360 3b53f96b111e5216c15f8dcb285a704f 278 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 273 8.6E-74 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 hmeg3_RS19360 3b53f96b111e5216c15f8dcb285a704f 278 SUPERFAMILY SSF53213 2 276 1.7E-93 T 28-03-2018 hmeg3_RS19030 dc012b409cd04f096549b8aa79f4f236 300 SUPERFAMILY SSF74650 6 298 2.45E-50 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS19030 dc012b409cd04f096549b8aa79f4f236 300 Pfam PF01263 Aldose 1-epimerase 8 295 3.3E-35 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 hmeg3_RS19030 dc012b409cd04f096549b8aa79f4f236 300 Gene3D G3DSA:2.70.98.10 2 300 3.5E-50 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 SUPERFAMILY SSF51366 4 217 4.84E-77 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 215 3.9E-98 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 Gene3D G3DSA:3.20.20.70 1 219 2.3E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 202 4.2E-91 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS04460 7be13dc3deae995407198d5b381aa395 220 PIRSF PIRSF001461 1 220 5.8E-105 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 hmeg3_RS17230 c1bd6d572e118306209463df5630ef14 915 Pfam PF01476 LysM domain 295 349 2.2E-4 T 28-03-2018 IPR018392 LysM domain hmeg3_RS17230 c1bd6d572e118306209463df5630ef14 915 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 301 373 5.6E-26 T 28-03-2018 IPR020012 Motility protein FimV, N-terminal hmeg3_RS17230 c1bd6d572e118306209463df5630ef14 915 Gene3D G3DSA:1.25.40.10 641 914 1.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS17230 c1bd6d572e118306209463df5630ef14 915 Gene3D G3DSA:3.10.350.10 281 368 1.6E-11 T 28-03-2018 hmeg3_RS17230 c1bd6d572e118306209463df5630ef14 915 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 871 914 5.2E-17 T 28-03-2018 IPR020011 Motility protein FimV, C-terminal hmeg3_RS22385 8928003eea69a61219fdf362ff60c4c5 264 Gene3D G3DSA:3.60.10.10 1 262 5.4E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS22385 8928003eea69a61219fdf362ff60c4c5 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 254 1.1E-19 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS22385 8928003eea69a61219fdf362ff60c4c5 264 SUPERFAMILY SSF56219 1 261 4.84E-47 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 Gene3D G3DSA:3.40.50.720 48 253 1.5E-61 T 28-03-2018 hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 3.2E-63 T 28-03-2018 hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 Gene3D G3DSA:3.40.50.10090 1 47 5.8E-8 T 28-03-2018 hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 SUPERFAMILY SSF51735 6 252 1.15E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 0.0061 T 28-03-2018 hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.7E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17395 04d889b79a267e1ebab9badeed0d9874 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00990 95a82260bb6a1979c31c5610621ae2cd 313 Pfam PF00296 Luciferase-like monooxygenase 33 234 7.5E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS00990 95a82260bb6a1979c31c5610621ae2cd 313 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 7 312 8.1E-106 T 28-03-2018 IPR020020 Luciferase-type oxidoreductase hmeg3_RS00990 95a82260bb6a1979c31c5610621ae2cd 313 SUPERFAMILY SSF51679 17 313 4.27E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS00990 95a82260bb6a1979c31c5610621ae2cd 313 Gene3D G3DSA:3.20.20.30 2 313 1.2E-51 T 28-03-2018 hmeg3_RS22660 d803ec005c12c3617324638cf324247e 257 SUPERFAMILY SSF161098 58 239 2.09E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS22660 d803ec005c12c3617324638cf324247e 257 Gene3D G3DSA:1.10.3720.10 4 254 4.1E-28 T 28-03-2018 hmeg3_RS22660 d803ec005c12c3617324638cf324247e 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 251 4.4E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 Gene3D G3DSA:3.40.50.2300 2 140 3.7E-23 T 28-03-2018 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 Pfam PF00072 Response regulator receiver domain 3 118 1.4E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 Gene3D G3DSA:1.10.10.10 141 196 2.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 SMART SM00421 138 195 2.4E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 194 5.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 3.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 3.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 3.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 SUPERFAMILY SSF52172 4 140 1.57E-26 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 SMART SM00448 1 118 4.7E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 SUPERFAMILY SSF46894 131 194 9.52E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS19720 3102aa7e838f8988f2da02c9c5e5a731 196 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10940 2b1b8837ac9851d7430f1e2e99aabf00 267 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS10940 2b1b8837ac9851d7430f1e2e99aabf00 267 Pfam PF00005 ABC transporter 43 184 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10940 2b1b8837ac9851d7430f1e2e99aabf00 267 SMART SM00382 51 232 1.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10940 2b1b8837ac9851d7430f1e2e99aabf00 267 Gene3D G3DSA:3.40.50.300 19 261 8.7E-63 T 28-03-2018 hmeg3_RS10940 2b1b8837ac9851d7430f1e2e99aabf00 267 SUPERFAMILY SSF52540 22 241 1.18E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 1.2E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 1.2E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 1.2E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 1.2E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 20 45 1.2E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 Gene3D G3DSA:1.10.287.950 318 514 2.4E-45 T 28-03-2018 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 Gene3D G3DSA:1.10.287.950 134 317 3.6E-23 T 28-03-2018 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 SMART SM00304 210 262 2.8E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 478 7.8E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 SMART SM00283 263 510 1.3E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 SUPERFAMILY SSF58104 230 511 1.19E-70 T 28-03-2018 hmeg3_RS09545 ddebdeca02f70ca0a9ea191e27675369 535 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 172 9.4E-9 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS17690 49c6d8f2da003695b78ea48426fb4988 592 SUPERFAMILY SSF54373 439 496 1.02E-7 T 28-03-2018 hmeg3_RS17690 49c6d8f2da003695b78ea48426fb4988 592 SUPERFAMILY SSF51905 522 583 2.99E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17690 49c6d8f2da003695b78ea48426fb4988 592 SUPERFAMILY SSF51905 7 342 2.99E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17690 49c6d8f2da003695b78ea48426fb4988 592 Pfam PF00732 GMC oxidoreductase 202 344 2.4E-9 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS17690 49c6d8f2da003695b78ea48426fb4988 592 Pfam PF05199 GMC oxidoreductase 447 572 2.8E-18 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS17690 49c6d8f2da003695b78ea48426fb4988 592 Gene3D G3DSA:3.50.50.60 2 585 3.5E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16250 20de87130b3b4f7d0def435ff7af109f 151 Gene3D G3DSA:3.10.129.10 1 139 3.4E-22 T 28-03-2018 hmeg3_RS16250 20de87130b3b4f7d0def435ff7af109f 151 PIRSF PIRSF020565 1 151 2.9E-51 T 28-03-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted hmeg3_RS16250 20de87130b3b4f7d0def435ff7af109f 151 SUPERFAMILY SSF54637 4 143 1.57E-21 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SMART SM00896 709 807 1.4E-33 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Pfam PF03147 Ferredoxin-fold anticodon binding domain 709 807 5.0E-27 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Gene3D G3DSA:2.40.50.140 39 144 8.0E-42 T 28-03-2018 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Gene3D G3DSA:3.50.40.10 201 400 1.7E-64 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SUPERFAMILY SSF55681 473 697 2.68E-46 T 28-03-2018 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SUPERFAMILY SSF46955 411 481 1.01E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Gene3D G3DSA:3.30.56.10 408 481 3.0E-22 T 28-03-2018 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Pfam PF03484 tRNA synthetase B5 domain 412 477 5.6E-18 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SUPERFAMILY SSF54991 704 807 2.75E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SUPERFAMILY SSF50249 35 202 7.43E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Pfam PF01588 Putative tRNA binding domain 45 150 1.2E-24 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SMART SM00874 409 477 1.9E-27 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Gene3D G3DSA:3.30.56.10 145 189 3.6E-6 T 28-03-2018 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 801 43.545 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Pfam PF03483 B3/4 domain 218 390 7.1E-62 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 807 3.4E-235 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SMART SM00873 217 390 2.5E-80 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Gene3D G3DSA:3.30.70.380 705 807 3.3E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 SUPERFAMILY SSF56037 203 391 2.28E-65 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 hmeg3_RS07775 58c4cc674af5ca9ec76b43c25fc06ece 808 Gene3D G3DSA:3.30.930.10 500 698 1.0E-35 T 28-03-2018 hmeg3_RS15525 5f2631d6a93895ee0de6c1e6e4cbfd1a 204 PIRSF PIRSF006324 1 204 5.5E-55 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS15525 5f2631d6a93895ee0de6c1e6e4cbfd1a 204 Pfam PF01810 LysE type translocator 13 201 1.2E-34 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS02910 012fe440e8d6cb6d82eda39d65a929af 232 Pfam PF13417 Glutathione S-transferase, N-terminal domain 30 101 1.3E-12 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS02910 012fe440e8d6cb6d82eda39d65a929af 232 Gene3D G3DSA:1.20.1050.10 112 229 6.1E-21 T 28-03-2018 hmeg3_RS02910 012fe440e8d6cb6d82eda39d65a929af 232 SUPERFAMILY SSF47616 102 220 1.26E-19 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS02910 012fe440e8d6cb6d82eda39d65a929af 232 Pfam PF14497 Glutathione S-transferase, C-terminal domain 151 221 8.5E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS02910 012fe440e8d6cb6d82eda39d65a929af 232 SUPERFAMILY SSF52833 24 106 1.37E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02910 012fe440e8d6cb6d82eda39d65a929af 232 Gene3D G3DSA:3.40.30.10 20 111 3.6E-20 T 28-03-2018 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 3.3E-55 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 PRINTS PR00834 HtrA/DegQ protease family signature 122 134 3.3E-55 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 PRINTS PR00834 HtrA/DegQ protease family signature 143 163 3.3E-55 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 PRINTS PR00834 HtrA/DegQ protease family signature 183 207 3.3E-55 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 3.3E-55 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 PRINTS PR00834 HtrA/DegQ protease family signature 326 338 3.3E-55 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 Pfam PF13180 PDZ domain 286 376 5.2E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 59 382 1.2E-131 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 SMART SM00228 286 368 2.1E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 Pfam PF13365 Trypsin-like peptidase domain 113 247 2.1E-33 T 28-03-2018 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 Gene3D G3DSA:2.40.10.10 164 276 1.2E-40 T 28-03-2018 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 SUPERFAMILY SSF50494 56 283 1.45E-67 T 28-03-2018 IPR009003 Peptidase S1, PA clan hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 Gene3D G3DSA:2.40.10.10 56 163 2.5E-36 T 28-03-2018 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 SUPERFAMILY SSF50156 245 367 1.58E-24 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS03550 6c183a82c47ae328709208c4a57cb758 389 Gene3D G3DSA:2.30.42.10 281 389 1.1E-26 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:2.30.38.10 1869 1951 1.1E-23 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:2.30.38.10 823 902 8.8E-15 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF52777 44 222 9.45E-34 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.50.980 505 659 4.6E-45 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.50.980 1563 1713 1.4E-36 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF51735 3077 3293 3.59E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF52777 1112 1281 2.78E-39 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.30.559.10 26 234 5.3E-27 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF47336 3577 3647 3.66E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 655 666 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.50.980 1714 1863 1.8E-30 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF47336 1019 1085 1.13E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF56801 1542 2057 2.49E-134 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00550 Phosphopantetheine attachment site 2077 2140 2.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00550 Phosphopantetheine attachment site 1026 1085 1.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00550 Phosphopantetheine attachment site 3583 3646 1.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF52151 2895 2986 1.44E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF52151 2694 2828 1.44E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SMART SM00823 Phosphopantetheine attachment site 1023 1092 1.0E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SMART SM00823 Phosphopantetheine attachment site 2075 2144 5.3E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SMART SM00823 Phosphopantetheine attachment site 3581 3650 2.3E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF13193 AMP-binding enzyme C-terminal domain 920 995 3.7E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF13193 AMP-binding enzyme C-terminal domain 1969 2042 1.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 535 936 3.6E-106 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1591 1984 1.1E-116 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.366.10 2691 2839 7.1E-38 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF56801 467 1035 1.83E-136 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00668 Condensation domain 41 481 2.6E-59 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00668 Condensation domain 1111 1541 4.6E-69 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.47.10 2155 2424 3.5E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.366.10 2884 3009 1.3E-23 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00501 AMP-binding enzyme 1570 1961 5.4E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00501 AMP-binding enzyme 512 912 3.5E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF51735 3306 3556 6.3E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1712 1723 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.30.300.30 907 1028 4.5E-25 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.30.300.30 1958 2081 7.4E-29 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.50.980 660 822 2.5E-38 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:1.10.1200.10 3573 3658 1.3E-20 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.30.70.250 2840 2883 1.0E-16 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF52777 233 476 1.22E-44 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2698 3002 1.3E-86 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00698 Acyl transferase domain 2697 2984 2.5E-38 T 28-03-2018 IPR014043 Acyl transferase hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:1.10.1200.10 1029 1091 1.1E-17 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:1.10.1200.10 2082 2146 3.8E-19 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.47.10 2429 2589 6.8E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1047 1062 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF47336 2074 2175 2.88E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SMART SM00825 Beta-ketoacyl synthase 2163 2591 2.5E-178 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2161 2413 2.9E-68 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF08659 KR domain 3308 3485 1.6E-43 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.30.559.10 1092 1304 2.5E-34 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Gene3D G3DSA:3.40.50.720 3304 3562 8.9E-39 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF52777 1289 1531 8.23E-47 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2539 2653 1.4E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2326 2342 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3308 3487 8.1E-36 T 28-03-2018 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3605 3620 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2421 2536 7.2E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF53901 2157 2279 5.89E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF53901 2309 2532 5.89E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF53901 2566 2586 5.89E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS11695 df229b323cae716c7fae0fb4a155d93f 3661 SUPERFAMILY SSF55048 2826 2894 6.8E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 Pfam PF03466 LysR substrate binding domain 101 308 8.4E-30 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 Gene3D G3DSA:3.40.190.10 104 195 4.8E-20 T 28-03-2018 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 SUPERFAMILY SSF46785 14 113 3.75E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 SUPERFAMILY SSF53850 102 311 2.17E-31 T 28-03-2018 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 4.8E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 Gene3D G3DSA:1.10.10.10 10 97 1.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22695 47bb1745a764a5cca6dd441582190595 314 Gene3D G3DSA:3.40.190.10 196 281 8.7E-13 T 28-03-2018 hmeg3_RS18010 5dbb4ca2012615576f7824481748ce8e 206 PRINTS PR01021 OMPA domain signature 145 161 6.8E-19 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18010 5dbb4ca2012615576f7824481748ce8e 206 PRINTS PR01021 OMPA domain signature 130 145 6.8E-19 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18010 5dbb4ca2012615576f7824481748ce8e 206 PRINTS PR01021 OMPA domain signature 100 122 6.8E-19 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18010 5dbb4ca2012615576f7824481748ce8e 206 Pfam PF00691 OmpA family 99 194 3.1E-23 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18010 5dbb4ca2012615576f7824481748ce8e 206 Gene3D G3DSA:3.30.1330.60 75 206 7.3E-45 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18010 5dbb4ca2012615576f7824481748ce8e 206 SUPERFAMILY SSF103088 89 200 3.79E-39 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS09880 fbe816971884558e1ba1c4f2c8920b9b 462 SUPERFAMILY SSF64383 319 445 7.19E-21 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 hmeg3_RS09880 fbe816971884558e1ba1c4f2c8920b9b 462 Gene3D G3DSA:3.30.1400.10 321 441 4.6E-23 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 hmeg3_RS09880 fbe816971884558e1ba1c4f2c8920b9b 462 SMART SM00771 320 438 1.3E-12 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 hmeg3_RS09880 fbe816971884558e1ba1c4f2c8920b9b 462 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 327 436 5.7E-11 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 hmeg3_RS14680 3a83f0665612303154a79b043980421f 330 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 130 1.4E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 hmeg3_RS14680 3a83f0665612303154a79b043980421f 330 Gene3D G3DSA:3.40.50.720 5 142 3.5E-32 T 28-03-2018 hmeg3_RS14680 3a83f0665612303154a79b043980421f 330 SUPERFAMILY SSF51735 7 162 1.41E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14680 3a83f0665612303154a79b043980421f 330 Gene3D G3DSA:3.30.360.10 143 326 1.4E-23 T 28-03-2018 hmeg3_RS14680 3a83f0665612303154a79b043980421f 330 SUPERFAMILY SSF55347 136 293 1.02E-20 T 28-03-2018 hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 95 3.2E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 9.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 9.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 Pfam PF07729 FCD domain 121 245 2.3E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 SMART SM00895 119 246 1.2E-20 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 SUPERFAMILY SSF46785 27 99 4.12E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 SMART SM00345 36 95 2.7E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 SUPERFAMILY SSF48008 117 253 1.07E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 Gene3D G3DSA:1.20.120.530 113 256 5.8E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS10700 621e3871d5a4c0fcae9bb264439efa0e 258 Gene3D G3DSA:1.10.10.10 26 96 9.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 Gene3D G3DSA:1.10.10.10 1 83 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 SUPERFAMILY SSF46785 1 111 8.16E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.3E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 Gene3D G3DSA:3.40.190.10 91 173 2.8E-11 T 28-03-2018 hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 Gene3D G3DSA:3.40.190.10 174 255 6.1E-13 T 28-03-2018 hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 SUPERFAMILY SSF53850 90 287 8.14E-40 T 28-03-2018 hmeg3_RS05780 37964142b69eb68540aeb875ddd16b11 291 Pfam PF03466 LysR substrate binding domain 88 284 8.8E-38 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04350 e4df28158a43d274b3910b4c650fe746 168 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 19 165 6.5E-50 T 28-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 hmeg3_RS04350 e4df28158a43d274b3910b4c650fe746 168 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 19 148 1.0E-20 T 28-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 hmeg3_RS04350 e4df28158a43d274b3910b4c650fe746 168 SUPERFAMILY SSF56925 6 168 1.33E-38 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS04350 e4df28158a43d274b3910b4c650fe746 168 Gene3D G3DSA:2.40.160.20 9 168 1.1E-44 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS22430 67bac1579b38815229b3ad4ad5dca7c2 612 SUPERFAMILY SSF48208 222 610 1.45E-88 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 hmeg3_RS22430 67bac1579b38815229b3ad4ad5dca7c2 612 Gene3D G3DSA:1.50.10.10 209 558 3.8E-84 T 28-03-2018 hmeg3_RS22430 67bac1579b38815229b3ad4ad5dca7c2 612 Gene3D G3DSA:1.50.10.10 559 611 0.11 T 28-03-2018 hmeg3_RS22430 67bac1579b38815229b3ad4ad5dca7c2 612 Pfam PF00723 Glycosyl hydrolases family 15 239 546 1.7E-29 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 Pfam PF00171 Aldehyde dehydrogenase family 33 483 1.4E-144 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 SUPERFAMILY SSF53720 17 487 1.57E-140 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 Gene3D G3DSA:3.40.309.10 278 468 4.5E-64 T 28-03-2018 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 Gene3D G3DSA:3.40.605.10 7 277 5.2E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 TIGRFAM TIGR03250 PhnAcAld_DH: putative phosphonoacetaldehyde dehydrogenase 18 488 7.1E-264 T 28-03-2018 IPR017656 Putative phosphonoacetaldehyde dehydrogenase KEGG: 00430+1.2.1.73|MetaCyc: PWY-5982 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 289 300 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09345 ea1b634b582e20fa107941dea027e22a 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Gene3D G3DSA:1.25.40.10 240 287 3.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Gene3D G3DSA:1.25.40.10 365 446 2.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Pfam PF00072 Response regulator receiver domain 15 128 1.4E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Pfam PF14559 Tetratricopeptide repeat 179 246 9.9E-8 T 28-03-2018 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SMART SM00448 12 128 1.9E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SMART SM00028 237 270 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SMART SM00028 169 202 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SMART SM00028 446 479 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SMART SM00028 382 415 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SMART SM00028 203 236 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SUPERFAMILY SSF48452 276 445 8.46E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Gene3D G3DSA:1.25.40.10 447 538 0.025 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Gene3D G3DSA:1.25.40.10 288 364 5.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Pfam PF13432 Tetratricopeptide repeat 277 338 0.0028 T 28-03-2018 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Gene3D G3DSA:1.25.40.10 148 239 2.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 Gene3D G3DSA:3.40.50.2300 9 147 3.0E-24 T 28-03-2018 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SUPERFAMILY SSF48452 169 341 1.58E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20170 9bae6ba71aebfa672ed032b2eece7bf6 542 SUPERFAMILY SSF52172 11 140 3.13E-23 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 SUPERFAMILY SSF56784 450 469 6.34E-53 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 SUPERFAMILY SSF56784 510 752 6.34E-53 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 453 459 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 Pfam PF00122 E1-E2 ATPase 251 431 2.7E-54 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 Pfam PF00702 haloacid dehalogenase-like hydrolase 448 665 1.0E-33 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 Gene3D G3DSA:3.40.1110.10 466 606 7.5E-40 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 SUPERFAMILY SSF81665 199 254 4.84E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 SUPERFAMILY SSF81665 351 437 4.84E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 200 755 1.3E-177 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 Gene3D G3DSA:3.30.70.100 47 120 2.1E-5 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 223 483 1.2E-35 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 552 731 7.3E-37 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 688 3.0E-24 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 671 3.0E-24 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 609 3.0E-24 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 300 314 3.0E-24 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 451 465 3.0E-24 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 SUPERFAMILY SSF81653 253 350 1.01E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 SUPERFAMILY SSF55008 51 109 3.93E-8 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 Gene3D G3DSA:1.20.1110.10 607 753 6.6E-21 T 28-03-2018 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00941 Cadmium-transporting ATPase signature 335 349 1.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00941 Cadmium-transporting ATPase signature 164 181 1.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00941 Cadmium-transporting ATPase signature 181 193 1.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00941 Cadmium-transporting ATPase signature 235 255 1.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 PRINTS PR00941 Cadmium-transporting ATPase signature 316 332 1.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14690 deb2b7cb77f63a4b8ce31693226d2f4e 759 Gene3D G3DSA:1.20.1110.10 143 465 7.0E-32 T 28-03-2018 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Pfam PF13291 ACT domain 684 762 4.1E-15 T 28-03-2018 IPR002912 ACT domain hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Gene3D G3DSA:3.10.20.30 433 506 5.4E-20 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 SUPERFAMILY SSF109604 55 242 1.36E-70 T 28-03-2018 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 SMART SM00954 286 396 1.7E-60 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Pfam PF04607 Region found in RelA / SpoT proteins 286 396 8.1E-32 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Gene3D G3DSA:3.30.460.10 245 376 6.6E-35 T 28-03-2018 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Gene3D G3DSA:3.30.70.260 685 764 1.6E-11 T 28-03-2018 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 77 760 2.6E-223 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 SMART SM00471 92 204 1.1E-10 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 SUPERFAMILY SSF55021 687 762 2.75E-6 T 28-03-2018 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 SUPERFAMILY SSF81301 232 443 3.43E-60 T 28-03-2018 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Pfam PF02824 TGS domain 439 498 1.5E-17 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 SUPERFAMILY SSF81271 426 499 2.18E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 hmeg3_RS13280 750467989facef610c1eb95a95ba3279 765 Pfam PF13328 HD domain 77 226 3.0E-50 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS00435 375b113f03350cbc108bdd0541bb49bb 317 Gene3D G3DSA:1.10.3720.10 3 304 5.9E-42 T 28-03-2018 hmeg3_RS00435 375b113f03350cbc108bdd0541bb49bb 317 SUPERFAMILY SSF161098 91 301 2.35E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00435 375b113f03350cbc108bdd0541bb49bb 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 315 1.8E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS22420 7e9724d8fd315ef2a50de3736280b34e 128 Pfam PF09723 Zinc ribbon domain 1 40 3.0E-15 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain hmeg3_RS22420 7e9724d8fd315ef2a50de3736280b34e 128 SMART SM00834 1 42 1.6E-18 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain hmeg3_RS22420 7e9724d8fd315ef2a50de3736280b34e 128 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 6.3E-22 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 Gene3D G3DSA:3.30.70.1450 172 292 1.0E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 SUPERFAMILY SSF116726 306 379 1.44E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 SUPERFAMILY SSF116726 230 288 1.01E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 394 546 3.5E-22 T 28-03-2018 IPR006512 YidE/YbjL duplication hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 2 562 1.8E-231 T 28-03-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 Gene3D G3DSA:3.30.70.1450 295 379 1.4E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 Pfam PF06826 Predicted Permease Membrane Region 15 178 9.8E-34 T 28-03-2018 IPR006512 YidE/YbjL duplication hmeg3_RS11995 93526c7ccc540d804c3a387291dd032e 562 Pfam PF06826 Predicted Permease Membrane Region 391 559 5.2E-33 T 28-03-2018 IPR006512 YidE/YbjL duplication hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 PIRSF PIRSF003180 18 427 7.3E-112 T 28-03-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 SUPERFAMILY SSF109604 199 423 1.0E-35 T 28-03-2018 hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 Pfam PF00563 EAL domain 16 208 1.3E-14 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 Pfam PF08668 HDOD domain 232 341 7.5E-12 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 Gene3D G3DSA:1.10.3210.10 211 333 3.9E-13 T 28-03-2018 hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 Gene3D G3DSA:3.20.20.450 12 210 3.4E-22 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 SMART SM00052 7 213 4.3E-6 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13315 13b6ad7bd95ac3f8ab9c465651cbcff0 445 SUPERFAMILY SSF141868 18 212 5.36E-29 T 28-03-2018 IPR001633 EAL domain hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Pfam PF00270 DEAD/DEAH box helicase 59 206 1.3E-5 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 626 702 1.1E-14 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Gene3D G3DSA:3.40.50.300 234 432 2.5E-44 T 28-03-2018 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Pfam PF11898 Domain of unknown function (DUF3418) 716 1345 2.4E-214 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Pfam PF04408 Helicase associated domain (HA2) 475 557 2.9E-18 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Gene3D G3DSA:3.40.50.300 49 208 1.6E-30 T 28-03-2018 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 SMART SM00490 312 412 2.6E-13 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 SMART SM00382 65 378 3.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 38 1019 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 Pfam PF00271 Helicase conserved C-terminal domain 295 411 1.9E-11 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 SUPERFAMILY SSF52540 47 245 1.25E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 SUPERFAMILY SSF52540 279 570 1.25E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 SMART SM00847 472 562 7.7E-36 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 hmeg3_RS17765 3829791eef808d8e63c5577938378a02 1349 SMART SM00487 48 240 3.9E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS12230 1c4d5b628708d3c5f04e420dda8fd0de 438 Pfam PF03929 PepSY-associated TM region 8 393 3.0E-55 T 28-03-2018 IPR005625 PepSY-associated TM protein hmeg3_RS13870 ebe51cee019ac0da51e5865d0ec11df0 450 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 9 450 6.0E-151 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS13870 ebe51cee019ac0da51e5865d0ec11df0 450 PIRSF PIRSF002746 4 450 6.7E-156 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS13870 ebe51cee019ac0da51e5865d0ec11df0 450 Pfam PF02447 GntP family permease 8 448 1.6E-162 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS00875 7a72804eb7b525f1a29fc8c22fb2aae3 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00875 7a72804eb7b525f1a29fc8c22fb2aae3 216 SMART SM00882 6 206 1.0E-79 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00875 7a72804eb7b525f1a29fc8c22fb2aae3 216 Pfam PF01144 Coenzyme A transferase 7 204 2.0E-37 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00875 7a72804eb7b525f1a29fc8c22fb2aae3 216 Gene3D G3DSA:3.40.1080.10 3 216 5.9E-70 T 28-03-2018 hmeg3_RS00875 7a72804eb7b525f1a29fc8c22fb2aae3 216 SUPERFAMILY SSF100950 3 214 2.97E-72 T 28-03-2018 hmeg3_RS00875 7a72804eb7b525f1a29fc8c22fb2aae3 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 3.2E-96 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF81665 245 299 2.62E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF81665 745 755 2.62E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF81665 397 490 2.62E-16 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Gene3D G3DSA:3.30.70.100 18 96 7.0E-7 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Gene3D G3DSA:3.30.70.100 97 178 3.3E-10 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF56784 554 795 4.01E-53 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF56784 496 515 4.01E-53 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Gene3D G3DSA:1.20.1110.10 207 512 1.6E-38 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 695 714 7.5E-24 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 719 731 7.5E-24 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 653 7.5E-24 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 346 360 7.5E-24 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 511 7.5E-24 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 227 797 3.0E-123 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 709 6.9E-41 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF81653 300 396 1.83E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 268 779 3.7E-79 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Pfam PF00122 E1-E2 ATPase 296 477 5.0E-56 T 28-03-2018 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 499 505 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00941 Cadmium-transporting ATPase signature 381 395 4.0E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00941 Cadmium-transporting ATPase signature 226 238 4.0E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00941 Cadmium-transporting ATPase signature 280 300 4.0E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00941 Cadmium-transporting ATPase signature 362 378 4.0E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 PRINTS PR00941 Cadmium-transporting ATPase signature 34 43 4.0E-15 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 245 798 6.4E-178 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Gene3D G3DSA:3.40.50.1000 621 763 3.5E-37 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Pfam PF00403 Heavy-metal-associated domain 33 88 4.3E-5 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF55008 28 98 1.57E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 Gene3D G3DSA:3.40.1110.10 513 620 2.3E-26 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS11830 133bc2ac5f63ed7b97aaa7eea94111d1 801 SUPERFAMILY SSF55008 100 171 4.32E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Gene3D G3DSA:2.160.10.10 85 204 3.3E-25 T 28-03-2018 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 262 46.035 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 176 261 4.2E-29 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Gene3D G3DSA:2.160.10.10 1 84 2.1E-14 T 28-03-2018 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 SUPERFAMILY SSF51161 3 262 5.66E-77 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 PIRSF PIRSF000456 1 262 1.2E-102 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 3 34 4.1E-4 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 139 1.3E-8 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 260 5.8E-103 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 hmeg3_RS09995 a9df724d0affb7a0481bd27096870270 262 Gene3D G3DSA:1.20.1180.10 205 262 6.9E-24 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 SMART SM00382 30 222 2.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 6 247 9.6E-118 T 28-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 221 242 2.1E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 Pfam PF00005 ABC transporter 22 172 5.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 SUPERFAMILY SSF52540 6 243 4.22E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04030 59e21cbad6de0bad3bb4da8933d3d5a1 247 Gene3D G3DSA:3.40.50.300 2 243 2.2E-61 T 28-03-2018 hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 SUPERFAMILY SSF50129 8 144 2.67E-35 T 28-03-2018 IPR011032 GroES-like hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 339 1.2E-142 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 2.9E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 Gene3D G3DSA:3.90.180.10 1 208 6.4E-53 T 28-03-2018 hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 SMART SM00829 13 336 2.7E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 SUPERFAMILY SSF51735 118 286 2.75E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 Pfam PF13602 Zinc-binding dehydrogenase 195 336 1.3E-20 T 28-03-2018 hmeg3_RS10625 7cb5166d947ab7dc62566fbc18df8e73 339 Gene3D G3DSA:3.90.180.10 220 337 1.1E-4 T 28-03-2018 hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.7E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 Gene3D G3DSA:3.40.190.10 94 179 5.4E-20 T 28-03-2018 hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 Pfam PF03466 LysR substrate binding domain 93 298 5.5E-37 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 SUPERFAMILY SSF46785 9 115 1.74E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 SUPERFAMILY SSF53850 95 301 5.43E-38 T 28-03-2018 hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 Gene3D G3DSA:1.10.10.10 1 88 4.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03855 dc83e799573d4e27f666e4ca6a9a00a3 303 Gene3D G3DSA:3.40.190.10 180 272 8.5E-16 T 28-03-2018 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 PRINTS PR00123 ATP synthase A subunit signature 251 266 1.2E-12 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 PRINTS PR00123 ATP synthase A subunit signature 98 114 1.2E-12 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 PRINTS PR00123 ATP synthase A subunit signature 197 219 1.2E-12 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 SUPERFAMILY SSF81336 91 264 3.79E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 Pfam PF00119 ATP synthase A chain 40 264 5.0E-54 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 Hamap MF_01393 ATP synthase subunit a [atpB]. 30 271 13.911 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 Gene3D G3DSA:1.20.120.220 89 271 5.4E-42 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 32 266 3.1E-40 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02415 d6fbac65dc1865da7c7370962fba4de2 271 ProSitePatterns PS00449 ATP synthase a subunit signature. 200 209 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 17 759 1.1E-234 T 28-03-2018 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 498 2.1E-134 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Gene3D G3DSA:2.120.10.90 521 769 7.9E-46 T 28-03-2018 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 SUPERFAMILY SSF56719 39 513 1.83E-150 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 12 768 32.666 T 28-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 675 716 2.0E-6 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 571 603 0.3 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Gene3D G3DSA:3.90.199.10 42 295 2.1E-112 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 SUPERFAMILY SSF101904 528 762 4.19E-47 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 SMART SM00434 19 491 4.4E-220 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS16435 5d25410aea6a682339784668b0594baf 770 Gene3D G3DSA:1.10.268.10 374 513 4.3E-44 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 Gene3D G3DSA:1.10.10.60 251 300 1.0E-13 T 28-03-2018 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 Gene3D G3DSA:1.10.10.60 192 250 6.0E-12 T 28-03-2018 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 Pfam PF12833 Helix-turn-helix domain 218 295 5.7E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 Gene3D G3DSA:2.60.120.280 39 183 1.1E-13 T 28-03-2018 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 Pfam PF12852 Cupin 3 179 3.1E-24 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 263 278 6.9E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 294 6.9E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 SUPERFAMILY SSF46689 248 298 4.33E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 SUPERFAMILY SSF51182 41 70 1.42E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 249 290 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 SUPERFAMILY SSF46689 195 245 4.07E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS13515 4d1ddd737fd6d1ded1a7a7808220aa8d 312 SMART SM00342 212 294 2.5E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 9 703 3.3E-241 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 261 287 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 119 139 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 329 341 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 239 260 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 91 116 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 166 187 3.5E-67 T 28-03-2018 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 279 301 5.1E-18 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 522 543 5.1E-18 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 45 64 5.1E-18 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 433 455 5.1E-18 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 93 113 5.1E-18 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 67 91 5.1E-18 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 73 130 7.5E-26 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13730 76fec13b95859a7a66ff5294310642d7 709 Pfam PF00361 Proton-conducting membrane transporter 142 424 3.1E-83 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 Pfam PF01965 DJ-1/PfpI family 35 170 3.1E-18 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 SUPERFAMILY SSF46689 208 255 1.16E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 SUPERFAMILY SSF46689 261 311 3.94E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 Gene3D G3DSA:3.40.50.880 1 227 2.3E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 SMART SM00342 225 308 2.2E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 Gene3D G3DSA:1.10.10.60 268 315 3.8E-9 T 28-03-2018 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 Pfam PF12833 Helix-turn-helix domain 231 309 6.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 Gene3D G3DSA:1.10.10.60 228 267 9.6E-13 T 28-03-2018 hmeg3_RS23930 a59ab60bd20e77bdecd65f329e6adeeb 315 SUPERFAMILY SSF52317 1 191 1.01E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS06465 790943738b6adde92ac4ae362041a18f 230 SUPERFAMILY SSF53448 2 208 5.53E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS06465 790943738b6adde92ac4ae362041a18f 230 Pfam PF00535 Glycosyl transferase family 2 4 128 1.0E-10 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS06465 790943738b6adde92ac4ae362041a18f 230 Gene3D G3DSA:3.90.550.10 1 215 7.7E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 SUPERFAMILY SSF81442 29 536 5.63E-194 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 Gene3D G3DSA:1.20.210.10 28 537 8.7E-222 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 482 8.9E-152 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 149 161 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 207 226 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 79 102 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 32 57 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 106 130 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 196 6.6E-120 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03290 b541f6538ca29a6a2c6f5835862fe0a5 537 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 33 536 1.1E-211 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 hmeg3_RS20375 f9e650db288518b7fa353ed9aa9b8c51 226 SUPERFAMILY SSF53056 6 213 4.84E-70 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS20375 f9e650db288518b7fa353ed9aa9b8c51 226 Pfam PF00484 Carbonic anhydrase 45 195 1.8E-46 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS20375 f9e650db288518b7fa353ed9aa9b8c51 226 Gene3D G3DSA:3.40.1050.10 5 222 1.9E-65 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS20375 f9e650db288518b7fa353ed9aa9b8c51 226 SMART SM00947 37 200 3.2E-58 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS24205 5178e40838ddeec2f79fb3aaa350dbae 405 SUPERFAMILY SSF53822 34 404 4.37E-94 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS24205 5178e40838ddeec2f79fb3aaa350dbae 405 Gene3D G3DSA:3.40.50.2300 30 170 6.0E-23 T 28-03-2018 hmeg3_RS24205 5178e40838ddeec2f79fb3aaa350dbae 405 Pfam PF13458 Periplasmic binding protein 34 369 6.8E-90 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS24205 5178e40838ddeec2f79fb3aaa350dbae 405 Gene3D G3DSA:3.40.50.2300 171 314 1.5E-32 T 28-03-2018 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SUPERFAMILY SSF52540 370 417 1.06E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SUPERFAMILY SSF52540 3 226 1.06E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SMART SM00957 4 404 0.0 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Pfam PF07516 SecA Wing and Scaffold domain 626 838 2.7E-66 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 19.897 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Gene3D G3DSA:3.10.450.50 745 924 4.0E-49 T 28-03-2018 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 ProSitePatterns PS01312 SecA family signature. 502 517 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Gene3D G3DSA:1.10.3060.10 643 744 1.2E-28 T 28-03-2018 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SUPERFAMILY SSF52540 418 627 1.8E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SMART SM00958 226 360 3.4E-79 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SUPERFAMILY SSF81767 225 370 4.32E-42 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Gene3D G3DSA:3.90.1440.10 241 370 5.2E-42 T 28-03-2018 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Pfam PF01043 SecA preprotein cross-linking domain 231 360 9.4E-36 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SUPERFAMILY SSF81886 900 912 4.84E-81 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 SUPERFAMILY SSF81886 631 849 4.84E-81 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 99 113 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 61 85 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 115 125 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 415 428 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 168 188 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 341 363 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 PRINTS PR00906 SecA protein signature 378 395 3.4E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Gene3D G3DSA:3.40.50.300 7 240 1.6E-54 T 28-03-2018 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 825 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Pfam PF07517 SecA DEAD-like domain 5 404 2.3E-132 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Gene3D G3DSA:3.40.50.300 419 642 2.5E-54 T 28-03-2018 hmeg3_RS21960 20eaf8187b7a264c5dcf94447abf3238 924 Pfam PF02810 SEC-C motif 904 922 1.8E-10 T 28-03-2018 IPR004027 SEC-C motif hmeg3_RS04040 2422e4e5583ad1058ec6bea991ba7204 200 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 16 195 3.2E-49 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 hmeg3_RS04040 2422e4e5583ad1058ec6bea991ba7204 200 Gene3D G3DSA:2.60.450.10 63 197 1.6E-7 T 28-03-2018 hmeg3_RS04040 2422e4e5583ad1058ec6bea991ba7204 200 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 22 196 8.4E-44 T 28-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 SUPERFAMILY SSF69075 331 431 1.12E-25 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 Gene3D G3DSA:1.10.1200.70 346 430 3.3E-23 T 28-03-2018 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 SUPERFAMILY SSF69742 1 172 1.7E-42 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 432 28.65 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 170 1.6E-45 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 186 320 1.1E-42 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 430 3.4E-122 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 113 136 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 Gene3D G3DSA:3.40.50.720 175 327 1.7E-22 T 28-03-2018 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 334 430 1.7E-26 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 PIRSF PIRSF000445 1 433 6.1E-142 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 hmeg3_RS02950 f74641add17552f7780430054c8e80ba 433 SUPERFAMILY SSF51735 177 329 1.73E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05295 f20aa477d42d853164f4fc082fa307a2 209 Gene3D G3DSA:3.40.50.360 1 208 3.2E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS05295 f20aa477d42d853164f4fc082fa307a2 209 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 203 24.572 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 hmeg3_RS05295 f20aa477d42d853164f4fc082fa307a2 209 SUPERFAMILY SSF52218 1 204 1.05E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS05295 f20aa477d42d853164f4fc082fa307a2 209 Pfam PF02525 Flavodoxin-like fold 1 198 3.1E-36 T 28-03-2018 IPR003680 Flavodoxin-like fold hmeg3_RS03280 13be0c46a3a177c2ef71e7f2b654a140 146 Pfam PF10003 Integral membrane protein (DUF2244) 8 142 5.2E-37 T 28-03-2018 IPR019253 Protein of unknown function DUF2244, transmembrane hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 PIRSF PIRSF016578 15 409 2.2E-34 T 28-03-2018 hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 21 412 2.4E-189 T 28-03-2018 IPR023922 Sulphate-starvation-induced SfnB hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 SUPERFAMILY SSF47203 251 411 4.83E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 27 133 2.1E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 255 388 2.6E-23 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 Gene3D G3DSA:1.10.540.10 25 136 2.3E-18 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 Gene3D G3DSA:2.40.110.10 137 236 1.5E-15 T 28-03-2018 hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 Gene3D G3DSA:1.20.140.10 237 413 6.6E-27 T 28-03-2018 hmeg3_RS23170 eebdb054146520383166572f1d6a5be4 413 SUPERFAMILY SSF56645 34 237 5.89E-46 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 SUPERFAMILY SSF56935 129 769 1.17E-101 T 28-03-2018 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 Gene3D G3DSA:2.40.170.20 247 769 1.7E-63 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 752 769 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 Pfam PF07660 Secretin and TonB N terminus short domain 38 84 9.1E-7 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 Pfam PF00593 TonB dependent receptor 302 767 1.5E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 Pfam PF07715 TonB-dependent Receptor Plug Domain 132 231 1.2E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 SMART SM00965 36 87 8.2E-11 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 Gene3D G3DSA:2.170.130.10 89 241 3.0E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23975 e37875cbc6cc493964ad58e3b434c1d3 769 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 134 769 1.2E-104 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 Pfam PF00285 Citrate synthase, C-terminal domain 71 388 2.8E-62 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 SUPERFAMILY SSF48256 29 396 3.79E-72 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 PRINTS PR00143 Citrate synthase signature 212 227 4.0E-12 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 PRINTS PR00143 Citrate synthase signature 290 310 4.0E-12 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 PRINTS PR00143 Citrate synthase signature 234 262 4.0E-12 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 Gene3D G3DSA:1.10.580.10 321 385 1.7E-5 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 Gene3D G3DSA:1.10.1660.10 1 69 4.7E-8 T 28-03-2018 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 Pfam PF12728 Helix-turn-helix domain 4 54 2.1E-6 T 28-03-2018 hmeg3_RS14700 b1b1bb17d78a0206b322aa1887d2f618 409 Gene3D G3DSA:1.10.580.10 74 302 6.9E-38 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 SMART SM00895 97 220 1.7E-14 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 Pfam PF07729 FCD domain 97 219 3.6E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 SUPERFAMILY SSF48008 94 226 2.88E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 SMART SM00345 29 87 7.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 Gene3D G3DSA:1.20.120.530 84 234 6.0E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 3.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 Gene3D G3DSA:1.10.10.10 9 83 5.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03050 15bf5ed7a3868e6588cd79b8ebd6c732 241 SUPERFAMILY SSF46785 23 91 5.93E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.1E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 Gene3D G3DSA:3.40.190.10 176 267 3.4E-26 T 28-03-2018 hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 Pfam PF03466 LysR substrate binding domain 87 285 3.4E-42 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 SUPERFAMILY SSF53850 90 294 2.17E-38 T 28-03-2018 hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 Gene3D G3DSA:1.10.10.10 1 91 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 SUPERFAMILY SSF46785 2 84 1.42E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01280 b379d8dcb2f325ed5baf962eeb1c0d76 301 Gene3D G3DSA:3.40.190.10 92 175 5.4E-21 T 28-03-2018 hmeg3_RS08605 ce15845be76782913e202816a8faeccb 267 Pfam PF13525 Outer membrane lipoprotein 35 238 1.9E-67 T 28-03-2018 hmeg3_RS08605 ce15845be76782913e202816a8faeccb 267 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 6 251 3.4E-86 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD hmeg3_RS08605 ce15845be76782913e202816a8faeccb 267 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 3 245 37.974 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD hmeg3_RS08605 ce15845be76782913e202816a8faeccb 267 Gene3D G3DSA:1.25.20.10 33 249 2.6E-19 T 28-03-2018 hmeg3_RS08605 ce15845be76782913e202816a8faeccb 267 SUPERFAMILY SSF48452 182 231 6.75E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08605 ce15845be76782913e202816a8faeccb 267 SUPERFAMILY SSF48452 38 110 6.75E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS13220 750bc61d5366136f30f62f6c41ba347b 342 SUPERFAMILY SSF53167 39 166 2.97E-42 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS13220 750bc61d5366136f30f62f6c41ba347b 342 SUPERFAMILY SSF53167 240 314 2.97E-42 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS13220 750bc61d5366136f30f62f6c41ba347b 342 Pfam PF01048 Phosphorylase superfamily 39 316 5.4E-45 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 hmeg3_RS13220 750bc61d5366136f30f62f6c41ba347b 342 Gene3D G3DSA:3.40.50.1580 22 338 1.3E-46 T 28-03-2018 hmeg3_RS00070 6040eb53ab5e5e83cb0c9d97c92c88cb 422 Gene3D G3DSA:3.50.50.60 1 422 2.2E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00070 6040eb53ab5e5e83cb0c9d97c92c88cb 422 SUPERFAMILY SSF51905 1 54 5.18E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00070 6040eb53ab5e5e83cb0c9d97c92c88cb 422 SUPERFAMILY SSF51905 364 419 5.18E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00070 6040eb53ab5e5e83cb0c9d97c92c88cb 422 SUPERFAMILY SSF51905 111 274 5.18E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00070 6040eb53ab5e5e83cb0c9d97c92c88cb 422 Pfam PF01266 FAD dependent oxidoreductase 2 401 4.2E-67 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS00070 6040eb53ab5e5e83cb0c9d97c92c88cb 422 SUPERFAMILY SSF54373 274 364 3.27E-17 T 28-03-2018 hmeg3_RS15650 e868e316ad10b934bff78c2f9a6b69af 257 SMART SM00382 26 213 1.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15650 e868e316ad10b934bff78c2f9a6b69af 257 PIRSF PIRSF039085 1 241 5.4E-119 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS15650 e868e316ad10b934bff78c2f9a6b69af 257 Pfam PF00005 ABC transporter 17 165 6.1E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS15650 e868e316ad10b934bff78c2f9a6b69af 257 Gene3D G3DSA:3.40.50.300 1 251 6.6E-77 T 28-03-2018 hmeg3_RS15650 e868e316ad10b934bff78c2f9a6b69af 257 SUPERFAMILY SSF52540 1 235 4.18E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15650 e868e316ad10b934bff78c2f9a6b69af 257 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24490 a1cf6c2345fa5bef44401c265966fff0 301 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 270 1.4E-46 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS24490 a1cf6c2345fa5bef44401c265966fff0 301 SUPERFAMILY SSF53850 1 273 5.1E-61 T 28-03-2018 hmeg3_RS24490 a1cf6c2345fa5bef44401c265966fff0 301 SMART SM00062 40 272 9.3E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS24490 a1cf6c2345fa5bef44401c265966fff0 301 Gene3D G3DSA:3.40.190.10 168 301 9.3E-19 T 28-03-2018 hmeg3_RS24490 a1cf6c2345fa5bef44401c265966fff0 301 Gene3D G3DSA:3.40.190.10 7 167 2.4E-24 T 28-03-2018 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.593 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 7.7E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 7.7E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 7.7E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 Pfam PF00203 Ribosomal protein S19 3 83 1.7E-37 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 PIRSF PIRSF002144 1 91 1.1E-33 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 Gene3D G3DSA:3.30.860.10 1 91 1.8E-41 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 2.9E-45 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22840 da8d93d81c3f4591463c300332d9dbde 91 SUPERFAMILY SSF54570 3 84 2.22E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 Pfam PF01037 Lrp/AsnC ligand binding domain 77 151 5.4E-21 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 SMART SM00344 11 120 3.7E-47 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 29 55 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 SUPERFAMILY SSF54909 73 160 2.41E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 Gene3D G3DSA:3.30.70.920 64 157 3.5E-26 T 28-03-2018 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 57 4.4E-19 T 28-03-2018 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 SUPERFAMILY SSF46785 10 70 1.59E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 8.1E-19 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 8.1E-19 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 8.1E-19 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14195 756e60d1d7f45a4fc24f3a0b8e438db7 162 Gene3D G3DSA:1.10.10.10 6 62 4.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 SUPERFAMILY SSF56784 3 221 1.28E-55 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 Gene3D G3DSA:3.40.50.1000 82 222 1.5E-32 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 56 189 4.3E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 Gene3D G3DSA:1.10.150.240 33 81 5.3E-20 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 Gene3D G3DSA:3.40.50.1000 1 32 0.22 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 8.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 8.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 8.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 216 4.5E-67 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 186 1.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS04455 a60eef1b838754d6d120f98a2a593d7d 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 192 1.5E-33 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 SUPERFAMILY SSF55874 285 430 6.42E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 294 3.3E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 SMART SM00388 230 295 1.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 Gene3D G3DSA:3.30.565.10 300 451 1.0E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 SMART SM00387 339 451 7.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 Gene3D G3DSA:1.20.5.1040 10 58 1.8E-9 T 28-03-2018 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 Gene3D G3DSA:1.20.5.1040 131 177 1.0E-9 T 28-03-2018 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 1.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 1.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 404 1.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 SUPERFAMILY SSF47384 215 294 1.08E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 Gene3D G3DSA:1.10.287.130 220 291 4.1E-10 T 28-03-2018 hmeg3_RS11905 189a0e1a6bb621c95a07aa84a15bc310 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 434 3.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS21175 5e48e295d0edd12c6c327cf63a660f33 364 Pfam PF00534 Glycosyl transferases group 1 181 336 2.6E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 hmeg3_RS21175 5e48e295d0edd12c6c327cf63a660f33 364 Pfam PF13579 Glycosyl transferase 4-like domain 61 146 1.6E-7 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 hmeg3_RS21175 5e48e295d0edd12c6c327cf63a660f33 364 SUPERFAMILY SSF53756 20 360 3.23E-59 T 28-03-2018 hmeg3_RS21175 5e48e295d0edd12c6c327cf63a660f33 364 Gene3D G3DSA:3.40.50.2000 19 164 2.9E-11 T 28-03-2018 hmeg3_RS21175 5e48e295d0edd12c6c327cf63a660f33 364 Gene3D G3DSA:3.40.50.2000 165 354 6.5E-37 T 28-03-2018 hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 Gene3D G3DSA:3.40.190.10 178 264 3.3E-25 T 28-03-2018 hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 SUPERFAMILY SSF53850 87 296 1.21E-42 T 28-03-2018 hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 Pfam PF03466 LysR substrate binding domain 89 293 3.2E-39 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 Gene3D G3DSA:3.40.190.10 92 177 1.3E-12 T 28-03-2018 hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 Gene3D G3DSA:1.10.10.10 3 84 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS09760 8afe245ffad856a4d1eac023db1218ee 302 SUPERFAMILY SSF46785 4 83 7.63E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23135 0a9bf331f1c46874184a26066876a575 459 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 11 436 1.6E-172 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS23135 0a9bf331f1c46874184a26066876a575 459 SUPERFAMILY SSF51679 6 439 1.44E-129 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS23135 0a9bf331f1c46874184a26066876a575 459 PIRSF PIRSF000337 6 451 2.9E-144 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS23135 0a9bf331f1c46874184a26066876a575 459 Gene3D G3DSA:3.20.20.30 5 458 1.9E-115 T 28-03-2018 hmeg3_RS23135 0a9bf331f1c46874184a26066876a575 459 Pfam PF00296 Luciferase-like monooxygenase 29 389 2.2E-59 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS12035 537600791b34090d954187922f6af574 286 SUPERFAMILY SSF46689 178 229 9.41E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS12035 537600791b34090d954187922f6af574 286 SMART SM00342 194 276 2.1E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS12035 537600791b34090d954187922f6af574 286 SUPERFAMILY SSF51215 25 136 6.15E-15 T 28-03-2018 hmeg3_RS12035 537600791b34090d954187922f6af574 286 Gene3D G3DSA:1.10.10.60 232 280 6.7E-12 T 28-03-2018 hmeg3_RS12035 537600791b34090d954187922f6af574 286 Gene3D G3DSA:1.10.10.60 124 231 2.3E-12 T 28-03-2018 hmeg3_RS12035 537600791b34090d954187922f6af574 286 Pfam PF02311 AraC-like ligand binding domain 19 131 6.2E-18 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 hmeg3_RS12035 537600791b34090d954187922f6af574 286 Gene3D G3DSA:2.60.120.10 9 92 3.0E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS12035 537600791b34090d954187922f6af574 286 Pfam PF12833 Helix-turn-helix domain 201 277 8.3E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS12035 537600791b34090d954187922f6af574 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 231 272 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS12035 537600791b34090d954187922f6af574 286 SUPERFAMILY SSF46689 231 279 3.94E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS08750 e070e2ed5ef9b929b5c07586e35745a4 136 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 21 127 3.5E-27 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08750 e070e2ed5ef9b929b5c07586e35745a4 136 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 18 129 1.2E-36 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08750 e070e2ed5ef9b929b5c07586e35745a4 136 SUPERFAMILY SSF81343 5 132 1.26E-29 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08750 e070e2ed5ef9b929b5c07586e35745a4 136 PIRSF PIRSF000178 3 133 1.1E-27 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08750 e070e2ed5ef9b929b5c07586e35745a4 136 Gene3D G3DSA:1.20.1300.10 21 135 1.5E-24 T 28-03-2018 hmeg3_RS03515 7ca07f6e8c55948868885f2907e19cfe 150 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 111 32.238 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 hmeg3_RS03515 7ca07f6e8c55948868885f2907e19cfe 150 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 109 3.0E-23 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 hmeg3_RS03515 7ca07f6e8c55948868885f2907e19cfe 150 SUPERFAMILY SSF141734 5 114 2.62E-47 T 28-03-2018 hmeg3_RS03515 7ca07f6e8c55948868885f2907e19cfe 150 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 107 2.3E-36 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 hmeg3_RS19890 45741b4822996739add9f74e5fddac34 117 Pfam PF12844 Helix-turn-helix domain 4 61 2.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS19890 45741b4822996739add9f74e5fddac34 117 SUPERFAMILY SSF47413 1 67 6.93E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS19890 45741b4822996739add9f74e5fddac34 117 Gene3D G3DSA:1.10.260.40 1 78 7.6E-15 T 28-03-2018 hmeg3_RS19890 45741b4822996739add9f74e5fddac34 117 SMART SM00530 6 61 2.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 Pfam PF00072 Response regulator receiver domain 15 124 2.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 Gene3D G3DSA:3.40.50.2300 5 171 9.5E-36 T 28-03-2018 hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 Pfam PF13188 PAS domain 182 229 2.7E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 SUPERFAMILY SSF52172 12 168 1.57E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 Gene3D G3DSA:3.30.450.20 172 248 5.5E-7 T 28-03-2018 hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 SMART SM00448 12 124 6.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS03620 eda79f6d575f79bbddb9c611d6d58594 272 SUPERFAMILY SSF55785 181 213 6.07E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS07000 d75ea3ac1dfb556482b516e1ecf8b19c 356 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 169 354 4.0E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS07000 d75ea3ac1dfb556482b516e1ecf8b19c 356 Gene3D G3DSA:1.10.3720.10 24 342 3.1E-46 T 28-03-2018 hmeg3_RS07000 d75ea3ac1dfb556482b516e1ecf8b19c 356 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 60 3.4E-7 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS07000 d75ea3ac1dfb556482b516e1ecf8b19c 356 SUPERFAMILY SSF161098 150 337 2.09E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS08130 2e49a037dc978998f9b93d9bbe56dee7 131 SMART SM00448 6 120 7.0E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08130 2e49a037dc978998f9b93d9bbe56dee7 131 Pfam PF00072 Response regulator receiver domain 9 119 4.2E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08130 2e49a037dc978998f9b93d9bbe56dee7 131 Gene3D G3DSA:3.40.50.2300 2 129 3.7E-37 T 28-03-2018 hmeg3_RS08130 2e49a037dc978998f9b93d9bbe56dee7 131 SUPERFAMILY SSF52172 5 125 1.85E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS09050 df90c804ad70c752e336b479e583fee9 130 Pfam PF07007 Lysozyme inhibitor LprI 26 115 3.3E-17 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal hmeg3_RS09050 df90c804ad70c752e336b479e583fee9 130 ProDom PD498860 RC0070 98 129 4.0E-4 T 28-03-2018 hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 SUPERFAMILY SSF50346 107 184 5.1E-17 T 28-03-2018 IPR011033 PRC-barrel-like hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 SUPERFAMILY SSF50447 14 100 3.88E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 Pfam PF05239 PRC-barrel domain 105 182 1.7E-5 T 28-03-2018 IPR027275 PRC-barrel domain hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 Gene3D G3DSA:2.40.30.60 14 101 2.9E-22 T 28-03-2018 IPR002676 RimM protein GO:0006364 hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 16 184 6.1E-44 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 Pfam PF01782 RimM N-terminal domain 18 97 3.6E-23 T 28-03-2018 IPR002676 RimM protein GO:0006364 hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 15 187 23.107 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 hmeg3_RS16035 dfb188e68ead4b0f86b52044b91f3a60 187 Gene3D G3DSA:2.30.30.240 103 182 9.4E-23 T 28-03-2018 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 328 488 4.2E-48 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 Pfam PF05683 Fumarase C-terminus 290 491 5.2E-81 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 PIRSF PIRSF001394 1 507 6.4E-212 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 SUPERFAMILY SSF117457 320 489 1.7E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 11 287 3.9E-62 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 Gene3D G3DSA:3.20.130.10 317 490 7.7E-65 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 hmeg3_RS15895 61a10301d88a05500a8a0268711688ac 514 Pfam PF05681 Fumarate hydratase (Fumerase) 11 286 2.1E-99 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 SUPERFAMILY SSF142695 204 365 3.66E-46 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 199 2.2E-73 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 PIRSF PIRSF001259 2 368 1.1E-117 T 28-03-2018 hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.984 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 SUPERFAMILY SSF55821 3 203 3.66E-86 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 Pfam PF00925 GTP cyclohydrolase II 207 364 2.0E-37 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 Gene3D G3DSA:3.90.870.10 1 212 4.2E-92 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain hmeg3_RS05615 9b7101b12b84c6c1b8c4929b194397b0 370 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 2.2E-82 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS00820 e3530b97bc325f09198428f9e4244721 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 4.8E-35 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00820 e3530b97bc325f09198428f9e4244721 286 Gene3D G3DSA:1.10.3470.10 1 277 1.0E-47 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 SUPERFAMILY SSF46689 238 283 1.61E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 239 281 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 Pfam PF06719 AraC-type transcriptional regulator N-terminus 24 173 5.4E-41 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 Gene3D G3DSA:1.10.10.60 136 241 7.8E-12 T 28-03-2018 hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 Gene3D G3DSA:1.10.10.60 242 287 1.1E-9 T 28-03-2018 hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 SMART SM00342 202 285 4.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 SUPERFAMILY SSF46689 188 236 2.87E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01840 0a5f8641def86f3cfcdfab6aee007070 294 Pfam PF12833 Helix-turn-helix domain 208 282 1.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 SUPERFAMILY SSF118215 8 404 2.48E-110 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 Gene3D G3DSA:1.10.3860.10 3 410 3.5E-105 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 3.6E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS11175 43abedb5de86cd9e6712e64626352a30 426 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 1.9E-29 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 Gene3D G3DSA:3.20.20.100 1 273 5.6E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 Pfam PF00248 Aldo/keto reductase family 25 257 7.0E-48 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 SUPERFAMILY SSF51430 3 262 7.46E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 8.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 8.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 8.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 8.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PRINTS PR00069 Aldo-keto reductase signature 35 59 8.1E-42 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PIRSF PIRSF000097 111 271 3.2E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS20590 a157c3221c6e3d26309eef7a2d21bba7 283 PIRSF PIRSF000097 1 114 5.1E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 802 909 2.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Pfam PF13493 Domain of unknown function (DUF4118) 423 527 9.8E-30 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Pfam PF00512 His Kinase A (phospho-acceptor) domain 689 754 5.4E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 SUPERFAMILY SSF55874 743 911 1.44E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 SUPERFAMILY SSF47384 682 755 2.16E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 SUPERFAMILY SSF55781 536 683 8.5E-6 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Gene3D G3DSA:1.20.120.620 423 521 2.8E-27 T 28-03-2018 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 853 863 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 893 906 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 886 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 835 849 9.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 SUPERFAMILY SSF52402 265 367 4.1E-8 T 28-03-2018 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Gene3D G3DSA:3.30.450.40 522 680 5.1E-9 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 SMART SM00388 688 754 5.5E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 SMART SM00387 798 909 8.2E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Gene3D G3DSA:1.10.287.130 681 748 3.9E-15 T 28-03-2018 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Gene3D G3DSA:3.40.50.300 35 162 3.6E-22 T 28-03-2018 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 36 244 1.5E-96 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Gene3D G3DSA:3.40.50.620 241 422 6.0E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Pfam PF13492 GAF domain 549 669 2.9E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS06060 678b0a6f47b34880df7cbb1b0c6c49ca 917 Gene3D G3DSA:3.30.565.10 749 909 2.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 SUPERFAMILY SSF56935 24 343 2.17E-54 T 28-03-2018 hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 Gene3D G3DSA:2.40.160.10 11 343 1.6E-52 T 28-03-2018 hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 PRINTS PR00184 Neisseria sp. porin signature 54 79 1.6E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 PRINTS PR00184 Neisseria sp. porin signature 89 108 1.6E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 PRINTS PR00184 Neisseria sp. porin signature 285 309 1.6E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 PRINTS PR00184 Neisseria sp. porin signature 147 164 1.6E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19630 480f4c1003912b77e65f3abefae877a6 343 Pfam PF13609 Gram-negative porin 8 314 3.0E-39 T 28-03-2018 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 Gene3D G3DSA:3.40.47.10 3 170 1.6E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 328 5.5E-122 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 1.5E-33 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 Gene3D G3DSA:3.40.47.10 171 328 1.2E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 SUPERFAMILY SSF53901 5 328 1.06E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 328 69.267 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 hmeg3_RS16745 70cba6a54c10c2f0d0c152c5ec4cf1f8 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 328 7.0E-37 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 hmeg3_RS14855 648f0928804202f6dda28654b86e98d5 284 Pfam PF07731 Multicopper oxidase 46 161 5.3E-22 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 hmeg3_RS14855 648f0928804202f6dda28654b86e98d5 284 Gene3D G3DSA:2.60.40.420 24 198 1.9E-33 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS14855 648f0928804202f6dda28654b86e98d5 284 SUPERFAMILY SSF49503 4 157 6.63E-32 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS14855 648f0928804202f6dda28654b86e98d5 284 ProSitePatterns PS00080 Multicopper oxidases signature 2. 145 156 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 hmeg3_RS00355 39f9d454067cdac62b342e7b3ed5a127 87 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.9E-31 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 hmeg3_RS00355 39f9d454067cdac62b342e7b3ed5a127 87 SUPERFAMILY SSF50249 1 71 1.03E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS00355 39f9d454067cdac62b342e7b3ed5a127 87 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 74 26.119 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 hmeg3_RS00355 39f9d454067cdac62b342e7b3ed5a127 87 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 2.4E-23 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 hmeg3_RS00355 39f9d454067cdac62b342e7b3ed5a127 87 Gene3D G3DSA:2.40.50.140 1 72 1.0E-31 T 28-03-2018 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Pfam PF00226 DnaJ domain 5 67 9.6E-30 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 SMART SM00271 4 62 3.3E-33 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 SUPERFAMILY SSF46565 1 108 5.76E-38 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 PRINTS PR00625 DnaJ domain signature 42 62 1.6E-33 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 PRINTS PR00625 DnaJ domain signature 62 81 1.6E-33 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 PRINTS PR00625 DnaJ domain signature 7 25 1.6E-33 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 PRINTS PR00625 DnaJ domain signature 25 40 1.6E-33 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Gene3D G3DSA:2.10.230.10 147 211 5.7E-20 T 28-03-2018 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Gene3D G3DSA:2.60.260.20 212 257 2.6E-12 T 28-03-2018 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Pfam PF00684 DnaJ central domain 150 210 9.2E-15 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Gene3D G3DSA:2.60.260.20 258 369 1.3E-28 T 28-03-2018 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 352 2.5E-138 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Pfam PF01556 DnaJ C terminal domain 124 336 4.6E-41 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 SUPERFAMILY SSF57938 137 213 5.62E-22 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Gene3D G3DSA:1.10.287.110 1 114 1.9E-37 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 28-03-2018 IPR018253 DnaJ domain, conserved site hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 375 42.139 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 SUPERFAMILY SSF49493 261 347 2.62E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 SUPERFAMILY SSF49493 217 260 3.79E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 hmeg3_RS20380 e7abd787ff96d9a1ff9f50e7cdc9a73f 377 SUPERFAMILY SSF49493 118 158 3.79E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 Gene3D G3DSA:1.20.58.220 118 236 1.1E-25 T 28-03-2018 hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 Pfam PF01895 PhoU domain 129 211 5.1E-15 T 28-03-2018 IPR026022 PhoU domain hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 Pfam PF01895 PhoU domain 23 108 1.2E-21 T 28-03-2018 IPR026022 PhoU domain hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 Gene3D G3DSA:1.20.58.220 2 116 2.4E-29 T 28-03-2018 hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 220 1.2E-67 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 PIRSF PIRSF003107 4 225 1.1E-61 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 hmeg3_RS06195 4074e2d5d037a6ad84554ab6e8bd2a0c 236 SUPERFAMILY SSF109755 8 224 1.47E-67 T 28-03-2018 hmeg3_RS10680 e0c61875442ae0c4c9dc616e365cf9b0 438 SUPERFAMILY SSF103473 20 432 4.05E-86 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10680 e0c61875442ae0c4c9dc616e365cf9b0 438 Gene3D G3DSA:1.20.1250.20 20 230 3.2E-40 T 28-03-2018 hmeg3_RS10680 e0c61875442ae0c4c9dc616e365cf9b0 438 Pfam PF07690 Major Facilitator Superfamily 35 397 4.1E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS10680 e0c61875442ae0c4c9dc616e365cf9b0 438 Gene3D G3DSA:1.20.1250.20 240 437 3.9E-23 T 28-03-2018 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 Pfam PF00107 Zinc-binding dehydrogenase 151 275 2.2E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 1.9E-151 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 Gene3D G3DSA:3.90.180.10 1 141 4.5E-41 T 28-03-2018 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 Gene3D G3DSA:3.40.50.720 142 248 1.8E-30 T 28-03-2018 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 99 1.2E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 SUPERFAMILY SSF50129 1 140 2.28E-38 T 28-03-2018 IPR011032 GroES-like hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 SUPERFAMILY SSF51735 111 287 1.07E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 Gene3D G3DSA:3.90.180.10 249 326 1.4E-8 T 28-03-2018 hmeg3_RS13805 5c6da0ffb6543009638ce542e85c3395 326 SMART SM00829 10 323 3.7E-47 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Gene3D G3DSA:3.30.1330.10 190 224 0.0065 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Gene3D G3DSA:3.30.1330.10 225 447 1.4E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF56042 454 637 8.07E-51 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Gene3D G3DSA:3.30.1330.10 666 835 8.9E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Pfam PF02769 AIR synthase related protein, C-terminal domain 860 1006 5.0E-9 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Pfam PF02769 AIR synthase related protein, C-terminal domain 454 611 6.9E-25 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF55326 227 449 1.92E-57 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF109736 161 226 5.1E-22 T 28-03-2018 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF52317 1084 1338 2.19E-90 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF82697 1 157 7.32E-42 T 28-03-2018 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Gene3D G3DSA:3.90.650.10 843 1042 1.4E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Gene3D G3DSA:3.90.650.10 448 629 1.3E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 5 1338 0.0 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Gene3D G3DSA:3.40.50.880 1086 1338 4.4E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1087 1338 7.7E-100 T 28-03-2018 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF55326 641 838 1.41E-66 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1339 21.182 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SMART SM01211 1087 1338 2.3E-143 T 28-03-2018 hmeg3_RS10630 6cbeae5c4ab29b98c6561524f154bbff 1339 SUPERFAMILY SSF56042 847 1080 2.99E-49 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 164 695 1.1E-117 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Gene3D G3DSA:3.30.365.10 588 757 2.4E-44 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 SUPERFAMILY SSF54665 15 152 5.5E-37 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 SUPERFAMILY SSF56003 162 754 9.16E-147 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Gene3D G3DSA:3.30.365.10 451 587 1.2E-29 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Gene3D G3DSA:3.30.365.10 276 441 1.7E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Gene3D G3DSA:3.30.365.10 165 275 2.0E-25 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 SMART SM01008 36 147 4.1E-39 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Gene3D G3DSA:3.90.1170.50 8 147 1.5E-34 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS23555 3f20f704fd4ff7e29db7c19c5faadd75 760 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 36 146 5.0E-22 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 SUPERFAMILY SSF51419 26 299 2.36E-77 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 Gene3D G3DSA:2.40.37.10 278 431 6.8E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 Gene3D G3DSA:3.20.20.10 34 277 3.5E-57 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01181 Diaminopimelate decarboxylase signature 84 101 9.6E-31 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01181 Diaminopimelate decarboxylase signature 315 333 9.6E-31 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01181 Diaminopimelate decarboxylase signature 173 182 9.6E-31 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01181 Diaminopimelate decarboxylase signature 395 417 9.6E-31 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 2.1E-25 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 86 98 2.1E-25 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 84 2.1E-25 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 2.1E-25 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 2.1E-25 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 428 41.654 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 SUPERFAMILY SSF50621 277 429 1.9E-53 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 30 385 4.0E-27 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 62 297 4.3E-67 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 hmeg3_RS22450 18d5a2c57f23dfabef4910642ca06d17 431 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 427 1.1E-155 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 Gene3D G3DSA:1.20.58.220 440 535 6.9E-8 T 28-03-2018 hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 SUPERFAMILY SSF109755 321 533 2.2E-33 T 28-03-2018 hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 306 5.9E-94 T 28-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 Gene3D G3DSA:1.20.58.220 324 439 2.8E-16 T 28-03-2018 hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 Pfam PF01895 PhoU domain 341 425 4.9E-11 T 28-03-2018 IPR026022 PhoU domain hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 Pfam PF02690 Na+/Pi-cotransporter 156 249 2.8E-9 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 hmeg3_RS15210 248a772bfbbca963b012172528e1dff9 566 Pfam PF02690 Na+/Pi-cotransporter 13 148 2.8E-32 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 hmeg3_RS22890 5a6742aa32ee6f45126f53aa95883783 379 Gene3D G3DSA:3.40.1570.10 32 212 1.1E-43 T 28-03-2018 hmeg3_RS22890 5a6742aa32ee6f45126f53aa95883783 379 Gene3D G3DSA:3.40.1570.10 220 378 1.8E-45 T 28-03-2018 hmeg3_RS22890 5a6742aa32ee6f45126f53aa95883783 379 Pfam PF05171 Haemin-degrading HemS.ChuX domain 244 376 5.1E-38 T 28-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 hmeg3_RS22890 5a6742aa32ee6f45126f53aa95883783 379 Pfam PF06228 Haem utilisation ChuX/HutX 52 188 2.5E-27 T 28-03-2018 IPR010413 Heme utilization carrier protein HutX-like hmeg3_RS22890 5a6742aa32ee6f45126f53aa95883783 379 SUPERFAMILY SSF144064 33 378 3.34E-104 T 28-03-2018 hmeg3_RS16770 dea52287447c9c26a0a5fb290f593ea5 221 SUPERFAMILY SSF52499 43 199 1.44E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS16770 dea52287447c9c26a0a5fb290f593ea5 221 Pfam PF00857 Isochorismatase family 54 186 7.3E-22 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS16770 dea52287447c9c26a0a5fb290f593ea5 221 Gene3D G3DSA:3.40.50.850 43 207 6.3E-24 T 28-03-2018 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 Gene3D G3DSA:3.40.50.300 5 54 5.6E-6 T 28-03-2018 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 10 187 1.5E-71 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 Gene3D G3DSA:3.30.63.10 55 87 1.2E-24 T 28-03-2018 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 Gene3D G3DSA:3.40.50.300 88 190 4.1E-27 T 28-03-2018 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 SMART SM00072 8 190 2.6E-56 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 SUPERFAMILY SSF52540 7 192 4.62E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 ProSitePatterns PS00856 Guanylate kinase-like signature. 43 60 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 Hamap MF_00328 Guanylate kinase [gmk]. 7 190 35.79 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 hmeg3_RS13270 b5a5e2118e462c2995120e5d7dbae36c 213 Pfam PF00625 Guanylate kinase 12 188 5.0E-47 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 Pfam PF02769 AIR synthase related protein, C-terminal domain 213 312 5.0E-11 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 TIGRFAM TIGR04049 AIR_rel_sll0787: AIR synthase-related protein, sll0787 family 17 334 2.1E-146 T 28-03-2018 IPR024030 AIR synthase-related protein, sll0787 family hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 Gene3D G3DSA:3.90.650.10 154 331 1.7E-21 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 164 8.1E-17 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 SUPERFAMILY SSF55326 27 166 1.41E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 PIRSF PIRSF036540 15 337 2.2E-99 T 28-03-2018 IPR011413 Uncharacterised conserved protein UCP036540 hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 SUPERFAMILY SSF56042 174 327 1.64E-22 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS03670 924dbb5566dcc4e76de85aa485740ddc 341 Gene3D G3DSA:3.30.1330.10 20 153 2.6E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS00535 91ecce571afbf9603996d7ba2bb2e6d6 159 Pfam PF03724 META domain 31 143 9.8E-26 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ hmeg3_RS00535 91ecce571afbf9603996d7ba2bb2e6d6 159 Gene3D G3DSA:3.40.190.10 1 139 6.6E-4 T 28-03-2018 hmeg3_RS20125 f550341a6c354ab6408b031141172899 522 Gene3D G3DSA:3.30.2010.10 77 170 6.2E-17 T 28-03-2018 hmeg3_RS20125 f550341a6c354ab6408b031141172899 522 SUPERFAMILY SSF48452 340 460 4.05E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20125 f550341a6c354ab6408b031141172899 522 Gene3D G3DSA:1.25.40.10 171 376 0.0066 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20125 f550341a6c354ab6408b031141172899 522 Pfam PF14559 Tetratricopeptide repeat 386 451 6.7E-6 T 28-03-2018 hmeg3_RS20125 f550341a6c354ab6408b031141172899 522 Gene3D G3DSA:1.25.40.10 377 512 2.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS20125 f550341a6c354ab6408b031141172899 522 Pfam PF01435 Peptidase family M48 120 285 3.9E-31 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 hmeg3_RS08260 b43e89be56376ae8bda08fb9bba20161 267 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 14 253 5.7E-69 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 hmeg3_RS08260 b43e89be56376ae8bda08fb9bba20161 267 Pfam PF01311 Bacterial export proteins, family 1 14 246 1.8E-68 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS08260 b43e89be56376ae8bda08fb9bba20161 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 2.4E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS08260 b43e89be56376ae8bda08fb9bba20161 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 2.4E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS08260 b43e89be56376ae8bda08fb9bba20161 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 2.4E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS08260 b43e89be56376ae8bda08fb9bba20161 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 2.4E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS08510 1d94a28d429c22f4cf06c500b23993f4 164 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 160 1.2E-67 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 hmeg3_RS08510 1d94a28d429c22f4cf06c500b23993f4 164 Gene3D G3DSA:3.30.1330.50 1 162 2.4E-72 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 hmeg3_RS08510 1d94a28d429c22f4cf06c500b23993f4 164 Pfam PF02542 YgbB family 5 158 1.2E-64 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 hmeg3_RS08510 1d94a28d429c22f4cf06c500b23993f4 164 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 36.045 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 hmeg3_RS08510 1d94a28d429c22f4cf06c500b23993f4 164 SUPERFAMILY SSF69765 4 160 1.96E-65 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 hmeg3_RS08510 1d94a28d429c22f4cf06c500b23993f4 164 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 hmeg3_RS20765 4d6807d19588344c3a86185b1dfcdf7f 292 PIRSF PIRSF016184 1 292 2.1E-58 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 hmeg3_RS20765 4d6807d19588344c3a86185b1dfcdf7f 292 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 283 9.8E-48 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 hmeg3_RS20765 4d6807d19588344c3a86185b1dfcdf7f 292 Gene3D G3DSA:3.10.310.10 1 123 3.3E-22 T 28-03-2018 hmeg3_RS20765 4d6807d19588344c3a86185b1dfcdf7f 292 Pfam PF02567 Phenazine biosynthesis-like protein 8 279 4.6E-44 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 hmeg3_RS20765 4d6807d19588344c3a86185b1dfcdf7f 292 SUPERFAMILY SSF54506 3 282 2.09E-57 T 28-03-2018 hmeg3_RS20765 4d6807d19588344c3a86185b1dfcdf7f 292 Gene3D G3DSA:3.10.310.10 124 281 8.2E-33 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Gene3D G3DSA:3.30.70.1430 38 140 1.3E-27 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82714 723 809 1.96E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82693 38 131 3.92E-26 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82693 566 670 1.78E-30 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82693 136 182 9.77E-27 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82693 274 330 9.77E-27 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82714 182 272 5.49E-23 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Gene3D G3DSA:3.30.2090.10 180 272 1.7E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1040 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Gene3D G3DSA:1.20.1640.10 273 500 1.1E-44 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Gene3D G3DSA:1.20.1640.10 828 1031 4.6E-34 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Gene3D G3DSA:3.30.70.1440 673 769 3.6E-18 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Gene3D G3DSA:3.30.70.1430 568 669 1.6E-19 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 3.8E-111 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82866 297 497 6.93E-48 T 28-03-2018 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00680 89ccb323afd56d74e9b569d803afa84c 1052 SUPERFAMILY SSF82866 807 1030 7.59E-42 T 28-03-2018 hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 Gene3D G3DSA:3.20.20.450 1 255 1.9E-62 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 SUPERFAMILY SSF54631 291 415 1.22E-10 T 28-03-2018 hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 SUPERFAMILY SSF141868 17 249 1.44E-61 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 Pfam PF00990 Diguanylate cyclase, GGDEF domain 422 508 7.0E-12 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 SMART SM00052 11 253 7.5E-37 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 SUPERFAMILY SSF55073 423 591 6.43E-24 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 Gene3D G3DSA:3.30.70.270 414 594 8.7E-27 T 28-03-2018 hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 Gene3D G3DSA:3.10.580.10 270 413 5.7E-13 T 28-03-2018 hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 Pfam PF00563 EAL domain 19 248 5.5E-46 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 435 590 4.3E-13 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16800 de4335ded1b3385af94d4b3d1f40b0fd 604 SMART SM00267 406 593 1.8E-10 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 Gene3D G3DSA:3.40.30.10 1 86 2.4E-25 T 28-03-2018 hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 5 84 1.1E-34 T 28-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 PRINTS PR00160 Glutaredoxin signature 48 61 1.8E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 PRINTS PR00160 Glutaredoxin signature 62 75 1.8E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 PRINTS PR00160 Glutaredoxin signature 5 23 1.8E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 SUPERFAMILY SSF52833 3 85 3.09E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS22590 701c4dfd207f15a686a0085b99637f19 86 Pfam PF00462 Glutaredoxin 5 65 5.9E-19 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 Gene3D G3DSA:1.10.10.10 3 86 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 Pfam PF03466 LysR substrate binding domain 88 290 2.2E-41 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 SUPERFAMILY SSF46785 4 87 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 Gene3D G3DSA:3.40.190.10 88 175 2.7E-14 T 28-03-2018 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.9E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 SUPERFAMILY SSF53850 90 295 3.26E-43 T 28-03-2018 hmeg3_RS00515 9ae49669581ffe4c5cec6ab3c7ffe9aa 300 Gene3D G3DSA:3.40.190.10 176 263 9.9E-25 T 28-03-2018 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 Gene3D G3DSA:3.30.450.90 1 100 3.5E-22 T 28-03-2018 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 5 343 3.8E-145 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 SMART SM00382 122 247 9.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 Gene3D G3DSA:3.40.50.300 114 272 6.6E-27 T 28-03-2018 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 Gene3D G3DSA:3.40.50.300 273 346 5.2E-13 T 28-03-2018 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 Pfam PF00437 Type II/IV secretion system protein 12 265 1.2E-44 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 hmeg3_RS04925 36adc84aa34558fae78425224dfa37ad 346 SUPERFAMILY SSF52540 6 336 4.36E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 SUPERFAMILY SSF74731 2 115 6.54E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 9.4E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 9.4E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 9.4E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-21 T 28-03-2018 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 3.1E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 Gene3D G3DSA:1.10.1900.20 55 116 1.8E-28 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 Pfam PF00453 Ribosomal protein L20 3 109 1.2E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.299 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS07765 9593e988b38336bd084840a2cbf646d6 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS17025 d996991bef7cd6ef548a7650800b3c81 199 Gene3D G3DSA:3.30.1450.10 111 198 0.037 T 28-03-2018 hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 12 252 1.6E-50 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 Gene3D G3DSA:3.90.25.10 179 333 4.7E-39 T 28-03-2018 hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 SUPERFAMILY SSF51735 4 329 1.74E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 Gene3D G3DSA:3.40.50.720 7 178 3.2E-22 T 28-03-2018 hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 PRINTS PR01713 Nucleotide sugar epimerase signature 246 261 1.2E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 PRINTS PR01713 Nucleotide sugar epimerase signature 288 305 1.2E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS21200 8cf710743daa686768fec4624d98c33f 334 PRINTS PR01713 Nucleotide sugar epimerase signature 223 238 1.2E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:3.10.20.30 15 136 1.3E-15 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:2.40.40.20 796 944 3.4E-35 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Pfam PF12838 4Fe-4S dicluster domain 171 228 4.2E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:3.40.50.740 301 503 1.0E-48 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:2.20.25.90 235 300 2.8E-15 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 247 922 2.0E-284 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 215 226 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 SMART SM00926 242 296 3.9E-14 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 SUPERFAMILY SSF50692 782 923 1.6E-40 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 SUPERFAMILY SSF54862 98 235 1.34E-38 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Pfam PF00384 Molybdopterin oxidoreductase 299 731 3.2E-75 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Pfam PF01568 Molydopterin dinucleotide binding domain 814 918 2.1E-28 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 100 1.2E-21 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 244 294 5.9E-15 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:3.30.70.20 148 181 3.9E-4 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 SUPERFAMILY SSF53706 244 829 3.27E-192 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 PIRSF PIRSF036643 15 953 0.0 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 145 2.0E-17 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:3.40.50.740 504 782 1.3E-76 T 28-03-2018 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 SUPERFAMILY SSF54292 20 97 3.0E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 SMART SM00929 106 146 1.3E-19 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16120 a1210ac60d9c2dc6ab9c182340caeaa0 959 Gene3D G3DSA:3.30.70.20 182 230 1.3E-9 T 28-03-2018 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 SMART SM00478 59 210 4.0E-48 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 Pfam PF14815 NUDIX domain 254 367 2.2E-22 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 26 293 3.0E-105 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 Gene3D G3DSA:1.10.1670.10 139 244 1.3E-33 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 Gene3D G3DSA:3.90.79.10 245 375 2.9E-10 T 28-03-2018 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 56 186 1.6E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 Pfam PF00633 Helix-hairpin-helix motif 119 148 4.8E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 ProSitePatterns PS01155 Endonuclease III family signature. 122 151 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 Gene3D G3DSA:1.10.340.30 41 138 5.0E-33 T 28-03-2018 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 212 228 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 SUPERFAMILY SSF48150 25 245 4.4E-72 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 hmeg3_RS04330 c1c909624904276fd3b180385a31ce57 378 SUPERFAMILY SSF55811 240 367 2.19E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Gene3D G3DSA:3.30.565.10 429 614 5.4E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SUPERFAMILY SSF50341 612 738 3.92E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SUPERFAMILY SSF47226 8 114 1.15E-25 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Gene3D G3DSA:2.40.50.180 628 691 4.2E-13 T 28-03-2018 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 612 2.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SUPERFAMILY SSF47384 368 428 7.06E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SUPERFAMILY SSF55874 429 611 3.8E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 368 424 1.2E-6 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Gene3D G3DSA:1.10.287.560 367 428 1.6E-10 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SMART SM00387 472 613 5.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Gene3D G3DSA:2.30.30.40 692 738 5.8E-20 T 28-03-2018 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SMART SM00073 1 100 7.3E-25 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SMART SM01231 367 427 4.1E-12 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 SMART SM00260 605 738 8.6E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Pfam PF01627 Hpt domain 7 105 5.4E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Pfam PF01584 CheW-like domain 619 739 2.9E-23 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 567 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 591 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 610 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20340 4348df461c215045c2675ab0db8722f8 762 Gene3D G3DSA:1.20.120.160 1 179 6.4E-27 T 28-03-2018 hmeg3_RS19315 4d86c2aa0f7c94975e5aff454b8358c9 145 SUPERFAMILY SSF54427 5 144 3.55E-26 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS19315 4d86c2aa0f7c94975e5aff454b8358c9 145 Gene3D G3DSA:3.10.450.50 3 144 8.0E-26 T 28-03-2018 hmeg3_RS19315 4d86c2aa0f7c94975e5aff454b8358c9 145 Pfam PF13577 SnoaL-like domain 11 140 6.3E-18 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS00170 505fa1f73a0d7f8d4c4fb984bd008c5c 144 Gene3D G3DSA:3.30.1330.40 9 135 3.8E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS00170 505fa1f73a0d7f8d4c4fb984bd008c5c 144 SUPERFAMILY SSF55298 25 135 1.48E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS00170 505fa1f73a0d7f8d4c4fb984bd008c5c 144 Pfam PF01042 Endoribonuclease L-PSP 24 134 9.8E-15 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS19290 5fded951e0c8577e3e63cc032a9c0a9d 249 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 85 238 3.4E-7 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS19290 5fded951e0c8577e3e63cc032a9c0a9d 249 SUPERFAMILY SSF56529 5 244 3.66E-35 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS19290 5fded951e0c8577e3e63cc032a9c0a9d 249 Gene3D G3DSA:3.90.850.10 1 249 1.1E-22 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS17940 ef348ec780e603f0cd34503c2819f22f 309 Gene3D G3DSA:3.40.1190.20 2 309 1.2E-59 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS17940 ef348ec780e603f0cd34503c2819f22f 309 Pfam PF00294 pfkB family carbohydrate kinase 11 301 8.3E-43 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB hmeg3_RS17940 ef348ec780e603f0cd34503c2819f22f 309 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 308 4.3E-122 T 28-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 hmeg3_RS17940 ef348ec780e603f0cd34503c2819f22f 309 SUPERFAMILY SSF53613 11 307 3.27E-56 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 SUPERFAMILY SSF54292 210 314 2.75E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 Gene3D G3DSA:2.40.30.10 2 101 2.4E-15 T 28-03-2018 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 76 90 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 52 66 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 90 104 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 137 146 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 187 195 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 30 40 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 40 52 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 112 131 1.5E-48 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 238 305 1.2E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 Gene3D G3DSA:3.40.50.80 102 217 9.9E-22 T 28-03-2018 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 265 273 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 SUPERFAMILY SSF52343 98 220 1.44E-25 T 28-03-2018 hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 Gene3D G3DSA:3.10.20.30 218 316 1.3E-22 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS00175 7d9a18f53f35ee42249c10fa8e4c0605 316 SUPERFAMILY SSF63380 4 100 2.0E-26 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 Pfam PF02954 Bacterial regulatory protein, Fis family 324 360 9.5E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 50 63 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 SMART SM00382 46 190 1.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 113 128 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 Gene3D G3DSA:1.10.10.60 268 366 6.2E-11 T 28-03-2018 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 Gene3D G3DSA:3.40.50.300 21 199 3.7E-21 T 28-03-2018 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 SUPERFAMILY SSF46689 324 362 5.89E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 SUPERFAMILY SSF52540 26 269 4.66E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 Pfam PF00158 Sigma-54 interaction domain 27 189 7.7E-61 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS04905 28d136735cb1b1c81986dacbfe723b9e 379 Gene3D G3DSA:1.10.8.60 200 267 2.9E-12 T 28-03-2018 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 89 107 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 7 328 2.7E-136 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 SUPERFAMILY SSF51395 8 315 8.55E-71 T 28-03-2018 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 331 50.563 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 Pfam PF01207 Dihydrouridine synthase (Dus) 10 314 9.2E-80 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 Gene3D G3DSA:3.20.20.70 5 245 9.1E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS05610 15cc9999432ffd014212bc0e3c2ad7ff 335 PIRSF PIRSF006621 1 327 3.7E-75 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 SUPERFAMILY SSF46785 2 93 3.79E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 Gene3D G3DSA:1.10.10.10 1 90 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 SMART SM00418 8 89 2.2E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 Pfam PF12840 Helix-turn-helix domain 10 69 1.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.9E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.9E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS14835 0ec44941dce3a4d476dade6c4cc4a43b 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.9E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 Gene3D G3DSA:3.40.50.300 19 300 7.7E-59 T 28-03-2018 hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 Gene3D G3DSA:3.40.50.300 301 628 4.4E-64 T 28-03-2018 hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 SMART SM00382 335 526 1.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 SMART SM00382 52 251 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 533 599 1.6E-9 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 SUPERFAMILY SSF52540 36 273 1.17E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 SUPERFAMILY SSF52540 303 547 2.66E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 Pfam PF00005 ABC transporter 326 478 5.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 Pfam PF00005 ABC transporter 43 201 8.0E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03780 b3cdb9f2a5aa87423a38a057f7a86f41 639 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS22500 f5a460143c07feab451fba9ae7699d3c 241 SUPERFAMILY SSF52540 4 239 1.93E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS22500 f5a460143c07feab451fba9ae7699d3c 241 Gene3D G3DSA:3.40.50.300 1 241 6.4E-56 T 28-03-2018 hmeg3_RS22500 f5a460143c07feab451fba9ae7699d3c 241 SMART SM00382 30 219 4.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22500 f5a460143c07feab451fba9ae7699d3c 241 PIRSF PIRSF039137 1 241 9.5E-106 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 hmeg3_RS22500 f5a460143c07feab451fba9ae7699d3c 241 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS22500 f5a460143c07feab451fba9ae7699d3c 241 Pfam PF00005 ABC transporter 22 168 1.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS18280 f5a460143c07feab451fba9ae7699d3c 241 SUPERFAMILY SSF52540 4 239 1.93E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18280 f5a460143c07feab451fba9ae7699d3c 241 Gene3D G3DSA:3.40.50.300 1 241 6.4E-56 T 28-03-2018 hmeg3_RS18280 f5a460143c07feab451fba9ae7699d3c 241 SMART SM00382 30 219 4.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS18280 f5a460143c07feab451fba9ae7699d3c 241 PIRSF PIRSF039137 1 241 9.5E-106 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 hmeg3_RS18280 f5a460143c07feab451fba9ae7699d3c 241 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS18280 f5a460143c07feab451fba9ae7699d3c 241 Pfam PF00005 ABC transporter 22 168 1.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09235 eaf4d46ecda52545914e8fc11de8b87b 236 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09235 eaf4d46ecda52545914e8fc11de8b87b 236 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 14 232 3.4E-95 T 28-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 hmeg3_RS09235 eaf4d46ecda52545914e8fc11de8b87b 236 SMART SM00382 43 232 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09235 eaf4d46ecda52545914e8fc11de8b87b 236 SUPERFAMILY SSF52540 15 229 1.82E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09235 eaf4d46ecda52545914e8fc11de8b87b 236 Gene3D G3DSA:3.40.50.300 10 234 3.3E-59 T 28-03-2018 hmeg3_RS09235 eaf4d46ecda52545914e8fc11de8b87b 236 Pfam PF00005 ABC transporter 34 182 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS22835 6e36574192567a183c7fff9945bad002 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22835 6e36574192567a183c7fff9945bad002 109 SUPERFAMILY SSF54843 1 108 4.06E-39 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22835 6e36574192567a183c7fff9945bad002 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 24.58 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22835 6e36574192567a183c7fff9945bad002 109 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 1.5E-34 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22835 6e36574192567a183c7fff9945bad002 109 Gene3D G3DSA:3.90.470.10 1 109 7.6E-40 T 28-03-2018 hmeg3_RS22835 6e36574192567a183c7fff9945bad002 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.3E-43 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 Pfam PF03466 LysR substrate binding domain 94 237 5.7E-18 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 Gene3D G3DSA:3.40.190.10 95 179 4.9E-12 T 28-03-2018 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 SUPERFAMILY SSF53850 94 283 1.32E-19 T 28-03-2018 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 Gene3D G3DSA:3.40.190.10 180 266 2.7E-7 T 28-03-2018 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.1E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 SUPERFAMILY SSF46785 8 91 1.68E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 Gene3D G3DSA:1.10.10.10 2 93 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16460 44ebd589d8508784d97a59cd952c4cbd 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07270 1d34db5dac2d5f8afcb97e1684fe35c1 240 Pfam PF10670 Domain of unknown function (DUF4198) 140 197 7.9E-9 T 28-03-2018 IPR019613 Protein of unknown function DUF4198 hmeg3_RS07270 1d34db5dac2d5f8afcb97e1684fe35c1 240 Gene3D G3DSA:2.60.40.10 145 227 0.001 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS09460 01b55a8e24313e655d39c0b5d4366917 345 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 164 330 2.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09460 01b55a8e24313e655d39c0b5d4366917 345 Gene3D G3DSA:1.10.3720.10 137 337 9.9E-21 T 28-03-2018 hmeg3_RS09460 01b55a8e24313e655d39c0b5d4366917 345 SUPERFAMILY SSF161098 142 322 1.27E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 261 43.501 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 Gene3D G3DSA:3.60.15.10 1 261 1.1E-70 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 261 8.8E-101 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 SUPERFAMILY SSF56281 2 260 3.67E-69 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 SMART SM00849 11 167 1.2E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 168 261 1.3E-24 T 28-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 PIRSF PIRSF005457 1 261 4.8E-101 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 hmeg3_RS07045 dcb9cc75f766d4e0ccda7f31a9130708 262 Pfam PF00753 Metallo-beta-lactamase superfamily 14 167 2.4E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 Pfam PF03466 LysR substrate binding domain 89 293 4.3E-43 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 SUPERFAMILY SSF53850 90 296 3.94E-45 T 28-03-2018 hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 Gene3D G3DSA:3.40.190.10 177 264 8.3E-28 T 28-03-2018 hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.9E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 SUPERFAMILY SSF46785 4 112 1.36E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 Gene3D G3DSA:1.10.10.10 2 86 3.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10620 cd3e1cffa5b393427a8fc6c0a6fee3cc 309 Gene3D G3DSA:3.40.190.10 87 176 5.9E-20 T 28-03-2018 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 Pfam PF05191 Adenylate kinase, active site lid 123 158 8.9E-18 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 187 3.3E-72 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 SUPERFAMILY SSF52540 1 185 1.74E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 PRINTS PR00094 Adenylate kinase signature 4 17 1.4E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 PRINTS PR00094 Adenylate kinase signature 81 97 1.4E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 PRINTS PR00094 Adenylate kinase signature 173 187 1.4E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 PRINTS PR00094 Adenylate kinase signature 156 171 1.4E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 PRINTS PR00094 Adenylate kinase signature 32 46 1.4E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 Gene3D G3DSA:3.40.50.300 1 218 5.1E-62 T 28-03-2018 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 Hamap MF_00235 Adenylate kinase [adk]. 1 217 52.799 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 hmeg3_RS18380 f3adce72ac5439af76ba3290c5e4e391 218 Pfam PF00406 Adenylate kinase 5 185 2.4E-57 T 28-03-2018 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 177 4.1E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 Pfam PF08281 Sigma-70, region 4 124 173 1.1E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 TIGRFAM TIGR02943 Sig70_famx1: RNA polymerase sigma-70 factor, TIGR02943 family 7 183 3.3E-65 T 28-03-2018 IPR014289 RNA polymerase sigma-24-related hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 SUPERFAMILY SSF88946 4 86 1.88E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 Gene3D G3DSA:1.10.10.10 108 181 9.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 Gene3D G3DSA:1.10.1740.10 2 78 1.6E-14 T 28-03-2018 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 Pfam PF04542 Sigma-70 region 2 14 75 7.2E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS06580 1cc950842b8ac5f19ce2e557ce52c5d1 189 SUPERFAMILY SSF88659 102 180 2.8E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 Gene3D G3DSA:3.40.50.720 1 248 1.1E-57 T 28-03-2018 hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 SUPERFAMILY SSF51735 1 239 7.5E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 7.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 7.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 7.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 7.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 Pfam PF00106 short chain dehydrogenase 2 181 3.1E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13520 0dc7fa34b92dec7a474c03d26582d624 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.2E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13685 8be58aa49336e830ebc1471cee58f9d8 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 279 1.4E-33 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS13685 8be58aa49336e830ebc1471cee58f9d8 296 Gene3D G3DSA:1.10.3470.10 1 283 1.2E-45 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS07975 d3fe8ff52b8d57cee14e512700b37193 361 PRINTS PR00184 Neisseria sp. porin signature 302 326 1.9E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS07975 d3fe8ff52b8d57cee14e512700b37193 361 PRINTS PR00184 Neisseria sp. porin signature 53 78 1.9E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS07975 d3fe8ff52b8d57cee14e512700b37193 361 PRINTS PR00184 Neisseria sp. porin signature 89 108 1.9E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS07975 d3fe8ff52b8d57cee14e512700b37193 361 SUPERFAMILY SSF56935 21 361 1.34E-53 T 28-03-2018 hmeg3_RS07975 d3fe8ff52b8d57cee14e512700b37193 361 Pfam PF13609 Gram-negative porin 9 330 1.1E-38 T 28-03-2018 hmeg3_RS07975 d3fe8ff52b8d57cee14e512700b37193 361 Gene3D G3DSA:2.40.160.10 7 361 2.5E-48 T 28-03-2018 hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 Pfam PF00005 ABC transporter 21 166 2.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 SMART SM00382 29 216 1.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 SUPERFAMILY SSF52540 3 241 4.28E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 Gene3D G3DSA:3.40.50.300 1 240 1.3E-67 T 28-03-2018 hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 SUPERFAMILY SSF50331 280 357 2.45E-8 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS17340 e19f4129eb446ce718440c5a1ea4a228 361 Pfam PF08402 TOBE domain 288 356 4.6E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Gene3D G3DSA:3.20.20.140 9 245 1.0E-27 T 28-03-2018 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 12 891 3.9E-166 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 293 715 2.7E-147 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Gene3D G3DSA:2.40.50.140 931 1046 1.8E-7 T 28-03-2018 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Pfam PF01336 OB-fold nucleic acid binding domain 964 1025 1.4E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Pfam PF02811 PHP domain 17 130 7.8E-15 T 28-03-2018 IPR004013 PHP domain GO:0003824 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 SUPERFAMILY SSF89550 17 72 1.16E-5 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 10 1051 13.545 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 Pfam PF14579 Helix-hairpin-helix motif 789 883 1.3E-17 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS15565 ae127d9173f6c70032d6bd065a009443 1051 SMART SM00481 11 78 8.7E-12 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal hmeg3_RS03975 05a7819d5d5f68aa429cab16701ea7a1 136 Pfam PF13673 Acetyltransferase (GNAT) domain 37 125 1.1E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS03975 05a7819d5d5f68aa429cab16701ea7a1 136 SUPERFAMILY SSF55729 13 121 1.96E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS03975 05a7819d5d5f68aa429cab16701ea7a1 136 Gene3D G3DSA:3.40.630.30 2 123 8.7E-15 T 28-03-2018 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 188 1.2E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 Pfam PF04542 Sigma-70 region 2 26 88 7.5E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 SUPERFAMILY SSF88659 127 188 6.92E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 Gene3D G3DSA:1.10.10.10 99 191 4.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 48 79 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 3 192 6.4E-98 T 28-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 Gene3D G3DSA:1.10.1740.10 2 98 9.0E-28 T 28-03-2018 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 SUPERFAMILY SSF88946 6 112 4.6E-32 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS16715 8309b2c0b086daf49bd82da80fd2e7a5 200 Pfam PF08281 Sigma-70, region 4 136 183 7.5E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12840 d67e9ef545a3e87b9cd5663a667730bc 498 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 477 1.3E-131 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS12840 d67e9ef545a3e87b9cd5663a667730bc 498 SUPERFAMILY SSF56954 11 479 4.05E-101 T 28-03-2018 hmeg3_RS12840 d67e9ef545a3e87b9cd5663a667730bc 498 Pfam PF02321 Outer membrane efflux protein 77 266 1.0E-22 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS12840 d67e9ef545a3e87b9cd5663a667730bc 498 Pfam PF02321 Outer membrane efflux protein 299 475 3.4E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS12840 d67e9ef545a3e87b9cd5663a667730bc 498 Gene3D G3DSA:1.20.1600.10 37 483 2.4E-95 T 28-03-2018 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 Pfam PF13609 Gram-negative porin 7 331 5.0E-61 T 28-03-2018 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00184 Neisseria sp. porin signature 303 327 3.0E-12 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00184 Neisseria sp. porin signature 156 173 3.0E-12 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00184 Neisseria sp. porin signature 56 81 3.0E-12 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 SUPERFAMILY SSF56935 24 358 1.7E-80 T 28-03-2018 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 Gene3D G3DSA:2.40.160.10 11 358 2.9E-76 T 28-03-2018 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 306 323 6.9E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 157 168 6.9E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 6.9E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05270 dae953b63c7e385319b07de34941a070 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 6.9E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS03305 6289939c3eb28d64981939a8b9b04e4b 286 Gene3D G3DSA:1.20.120.80 75 286 5.5E-70 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03305 6289939c3eb28d64981939a8b9b04e4b 286 Gene3D G3DSA:1.10.287.70 4 74 7.7E-17 T 28-03-2018 hmeg3_RS03305 6289939c3eb28d64981939a8b9b04e4b 286 SUPERFAMILY SSF81452 6 286 7.22E-80 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03305 6289939c3eb28d64981939a8b9b04e4b 286 Pfam PF00510 Cytochrome c oxidase subunit III 11 285 2.2E-58 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 Gene3D G3DSA:3.20.19.10 624 863 1.0E-67 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 Pfam PF00330 Aconitase family (aconitate hydratase) 70 538 2.9E-147 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 191 204 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 281 294 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 205 220 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 267 280 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 162 170 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 407 418 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 138 151 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 360 374 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 PRINTS PR00415 Aconitase family signature 469 482 1.2E-28 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 Gene3D G3DSA:3.30.499.10 2 227 3.2E-59 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 Pfam PF00694 Aconitase C-terminal domain 661 791 6.2E-30 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 863 0.0 T 28-03-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 SUPERFAMILY SSF52016 603 861 5.1E-67 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 Gene3D G3DSA:3.40.1060.10 228 359 9.7E-41 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 Gene3D G3DSA:3.30.499.10 360 552 2.8E-53 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS15430 e9a1c5fe6c39622cc2609034748cf186 869 SUPERFAMILY SSF53732 15 591 3.01E-182 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 Gene3D G3DSA:1.20.1250.20 1 189 4.3E-27 T 28-03-2018 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 SUPERFAMILY SSF103473 3 179 3.27E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 SUPERFAMILY SSF103473 188 437 9.16E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 66 88 8.4E-5 T 28-03-2018 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 8.4E-5 T 28-03-2018 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 6 30 8.4E-5 T 28-03-2018 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 152 8.4E-5 T 28-03-2018 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 Gene3D G3DSA:1.20.1250.20 249 448 2.0E-26 T 28-03-2018 hmeg3_RS05785 1ef6e0b08730bc10370e82218f248076 454 Pfam PF07690 Major Facilitator Superfamily 7 335 1.2E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 Gene3D G3DSA:3.20.20.140 78 404 1.0E-74 T 28-03-2018 hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 Gene3D G3DSA:2.30.40.10 9 77 3.8E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 Pfam PF07969 Amidohydrolase family 53 466 2.2E-43 T 28-03-2018 IPR013108 Amidohydrolase 3 hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 SUPERFAMILY SSF51338 422 471 4.78E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 SUPERFAMILY SSF51338 10 63 4.78E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 SUPERFAMILY SSF51556 64 422 9.35E-88 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS13880 eaf019b4c18134ee1eed778872ebb051 498 Gene3D G3DSA:2.30.40.10 405 470 5.8E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS05160 6ac9714ef5c7bc0d2be269303da51512 154 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 3.8E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05160 6ac9714ef5c7bc0d2be269303da51512 154 SUPERFAMILY SSF54523 12 132 3.92E-18 T 28-03-2018 hmeg3_RS05160 6ac9714ef5c7bc0d2be269303da51512 154 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 32 4.4E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05160 6ac9714ef5c7bc0d2be269303da51512 154 Gene3D G3DSA:3.30.700.10 12 154 3.0E-16 T 28-03-2018 hmeg3_RS05160 6ac9714ef5c7bc0d2be269303da51512 154 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 33 132 7.8E-17 T 28-03-2018 IPR031982 Type IV minor pilin ComP hmeg3_RS01195 15779353ad5c763fe8ee85d5d4423d79 395 Gene3D G3DSA:3.40.50.2300 163 289 8.4E-30 T 28-03-2018 hmeg3_RS01195 15779353ad5c763fe8ee85d5d4423d79 395 Gene3D G3DSA:3.40.50.2300 27 162 6.8E-12 T 28-03-2018 hmeg3_RS01195 15779353ad5c763fe8ee85d5d4423d79 395 Pfam PF13458 Periplasmic binding protein 32 376 3.0E-63 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS01195 15779353ad5c763fe8ee85d5d4423d79 395 SUPERFAMILY SSF53822 32 387 2.15E-79 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01195 15779353ad5c763fe8ee85d5d4423d79 395 Gene3D G3DSA:3.40.50.2300 290 365 0.024 T 28-03-2018 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 SMART SM00342 172 254 1.5E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 Gene3D G3DSA:1.10.10.60 129 208 0.0063 T 28-03-2018 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 Gene3D G3DSA:1.10.10.60 209 268 4.3E-11 T 28-03-2018 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 SUPERFAMILY SSF46689 208 256 2.73E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 Pfam PF12833 Helix-turn-helix domain 178 254 2.9E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 223 238 3.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 254 3.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS06215 bb1e600753432b2468bf1c012910ca38 269 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 250 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Gene3D G3DSA:2.60.40.10 462 559 2.3E-33 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Gene3D G3DSA:3.20.20.80 23 366 1.1E-9 T 28-03-2018 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Gene3D G3DSA:3.20.20.80 686 1054 6.1E-61 T 28-03-2018 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Gene3D G3DSA:1.20.58.280 560 660 2.4E-8 T 28-03-2018 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Gene3D G3DSA:2.60.40.1180 1055 1170 9.0E-25 T 28-03-2018 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 SUPERFAMILY SSF51445 81 319 2.56E-16 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 462 1167 46.047 T 28-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 SUPERFAMILY SSF51445 688 1051 1.14E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 Pfam PF11896 Domain of unknown function (DUF3416) 465 684 9.0E-52 T 28-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 hmeg3_RS11320 d4412a3abdc83196a75289dfb74462e5 1170 SMART SM00642 694 1044 5.0E-5 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS02705 1fd09c7ea616a944336d19eb26114983 315 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 102 311 2.3E-18 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 hmeg3_RS02705 1fd09c7ea616a944336d19eb26114983 315 PIRSF PIRSF017082 11 315 2.4E-67 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 hmeg3_RS02705 1fd09c7ea616a944336d19eb26114983 315 Gene3D G3DSA:3.40.190.10 112 226 3.2E-15 T 28-03-2018 hmeg3_RS02705 1fd09c7ea616a944336d19eb26114983 315 SUPERFAMILY SSF53850 91 231 4.44E-10 T 28-03-2018 hmeg3_RS04535 460b79247a196f3a49dbf6f0e2afc66c 268 Gene3D G3DSA:3.40.190.10 28 133 1.0E-28 T 28-03-2018 hmeg3_RS04535 460b79247a196f3a49dbf6f0e2afc66c 268 Gene3D G3DSA:3.40.190.10 134 214 1.8E-18 T 28-03-2018 hmeg3_RS04535 460b79247a196f3a49dbf6f0e2afc66c 268 SMART SM00062 38 258 4.2E-51 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04535 460b79247a196f3a49dbf6f0e2afc66c 268 SUPERFAMILY SSF53850 9 258 1.7E-58 T 28-03-2018 hmeg3_RS04535 460b79247a196f3a49dbf6f0e2afc66c 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 256 1.9E-54 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 6.0E-105 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 5.6E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 Gene3D G3DSA:3.90.180.10 1 134 3.6E-39 T 28-03-2018 hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 SUPERFAMILY SSF50129 1 146 1.73E-36 T 28-03-2018 IPR011032 GroES-like hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 Gene3D G3DSA:3.40.50.720 135 310 1.8E-38 T 28-03-2018 hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 SUPERFAMILY SSF51735 112 288 2.13E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 SMART SM00829 10 324 2.3E-55 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS23765 6175a6f3a56d004b77e6ccb33ae0e68b 326 Pfam PF00107 Zinc-binding dehydrogenase 152 270 8.3E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 Hamap MF_00564 Ribonuclease PH [rph]. 5 241 48.022 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 SUPERFAMILY SSF54211 5 185 1.52E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 6 240 6.4E-114 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.6E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 Pfam PF03725 3' exoribonuclease family, domain 2 162 227 4.4E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 Gene3D G3DSA:3.30.230.70 2 243 7.3E-58 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 SUPERFAMILY SSF55666 156 240 7.33E-25 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13260 e71403ae5517706e510684afcd268b10 244 ProSitePatterns PS01277 Ribonuclease PH signature. 120 133 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PIRSF PIRSF000126 1 269 1.3E-73 T 28-03-2018 hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 Pfam PF00106 short chain dehydrogenase 13 203 1.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 Gene3D G3DSA:3.40.50.720 9 269 1.3E-52 T 28-03-2018 hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00905 966b51d92dfaa82e14fcd39edf57cdf5 269 SUPERFAMILY SSF51735 10 231 4.13E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 Pfam PF00563 EAL domain 153 386 4.3E-72 T 28-03-2018 IPR001633 EAL domain hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 Gene3D G3DSA:3.40.50.2300 12 152 5.5E-21 T 28-03-2018 hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 Gene3D G3DSA:3.20.20.450 153 405 2.8E-87 T 28-03-2018 IPR001633 EAL domain hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 SMART SM00052 146 391 1.9E-89 T 28-03-2018 IPR001633 EAL domain hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 SUPERFAMILY SSF141868 153 399 4.97E-82 T 28-03-2018 IPR001633 EAL domain hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 SUPERFAMILY SSF52172 12 142 9.25E-24 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 SMART SM00448 11 130 2.4E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20305 497e0f9eae52f569b65ecfe31388b680 423 Pfam PF00072 Response regulator receiver domain 14 130 6.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23315 88f8308c09035d3208c7bc1f6b0c4bbc 422 Gene3D G3DSA:1.20.1250.20 224 420 2.8E-17 T 28-03-2018 hmeg3_RS23315 88f8308c09035d3208c7bc1f6b0c4bbc 422 Pfam PF07690 Major Facilitator Superfamily 44 345 3.0E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS23315 88f8308c09035d3208c7bc1f6b0c4bbc 422 SUPERFAMILY SSF103473 37 416 7.19E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS23315 88f8308c09035d3208c7bc1f6b0c4bbc 422 Gene3D G3DSA:1.20.1250.20 31 222 1.6E-19 T 28-03-2018 hmeg3_RS20565 4cf0fcf3c35353b9f965b5f4f0050d8d 400 SUPERFAMILY SSF111352 6 374 2.35E-95 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 hmeg3_RS20565 4cf0fcf3c35353b9f965b5f4f0050d8d 400 ProSitePatterns PS01219 Ammonium transporters signature. 156 181 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 hmeg3_RS20565 4cf0fcf3c35353b9f965b5f4f0050d8d 400 Gene3D G3DSA:1.10.3430.10 1 374 1.5E-91 T 28-03-2018 hmeg3_RS20565 4cf0fcf3c35353b9f965b5f4f0050d8d 400 Pfam PF00909 Ammonium Transporter Family 12 389 2.0E-87 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 hmeg3_RS23175 8b77536faf84b68a0383b35d47f96740 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 1.7E-14 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 hmeg3_RS23175 8b77536faf84b68a0383b35d47f96740 226 SMART SM00702 1 177 1.4E-24 T 28-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 hmeg3_RS23175 8b77536faf84b68a0383b35d47f96740 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 44.274 T 28-03-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 hmeg3_RS23175 8b77536faf84b68a0383b35d47f96740 226 Gene3D G3DSA:2.60.120.620 2 189 8.8E-33 T 28-03-2018 hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 3 76 2.0E-16 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 45 59 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 112 11.545 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 Gene3D G3DSA:3.30.230.10 1 114 3.6E-23 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 SUPERFAMILY SSF54211 2 103 3.29E-19 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 85 2.0E-12 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 hmeg3_RS02585 3f5743f3e612735093427214b36b926a 122 Pfam PF00825 Ribonuclease P 3 102 7.9E-19 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 24 540 8.1E-206 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SMART SM00316 210 280 1.4E-29 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SMART SM00316 39 107 6.0E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SMART SM00316 295 367 7.1E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SMART SM00316 382 454 7.3E-20 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SMART SM00316 123 191 6.0E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SMART SM00316 469 540 6.2E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Gene3D G3DSA:2.40.50.140 116 197 1.7E-9 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Gene3D G3DSA:2.40.50.140 202 286 2.1E-27 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Gene3D G3DSA:2.40.50.140 19 112 9.3E-8 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SUPERFAMILY SSF50249 367 457 6.27E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SUPERFAMILY SSF50249 275 374 7.86E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SUPERFAMILY SSF50249 28 132 2.14E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 59 73 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 146 163 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 41 59 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 104 123 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 175 195 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 350 368 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 128 144 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 310 329 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PRINTS PR00681 Ribosomal protein S1 signature 232 253 2.6E-81 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 PIRSF PIRSF002111 9 554 3.6E-215 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Gene3D G3DSA:2.40.50.140 472 567 2.7E-21 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Pfam PF00575 S1 RNA binding domain 123 191 3.5E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Pfam PF00575 S1 RNA binding domain 470 540 1.1E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Pfam PF00575 S1 RNA binding domain 39 105 1.1E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Pfam PF00575 S1 RNA binding domain 381 454 7.4E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Pfam PF00575 S1 RNA binding domain 209 280 1.7E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Pfam PF00575 S1 RNA binding domain 296 367 5.0E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SUPERFAMILY SSF50249 209 297 4.29E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SUPERFAMILY SSF50249 449 557 5.15E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Gene3D G3DSA:2.40.50.140 294 368 8.9E-26 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 Gene3D G3DSA:2.40.50.140 381 455 4.8E-19 T 28-03-2018 hmeg3_RS17965 62099b0c89c62631033c27fb02a36893 579 SUPERFAMILY SSF50249 122 205 8.58E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 Gene3D G3DSA:3.40.47.10 6 152 1.6E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 Pfam PF02803 Thiolase, C-terminal domain 291 411 9.1E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 411 1.7E-108 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 Gene3D G3DSA:3.40.47.10 163 410 2.4E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 SUPERFAMILY SSF53901 247 411 2.18E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 SUPERFAMILY SSF53901 10 133 2.18E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 PIRSF PIRSF000429 8 414 5.7E-105 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 ProSitePatterns PS00737 Thiolases signature 2. 359 375 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 hmeg3_RS01120 21e813a5ddf4bc919e6c312a75744ffb 418 Pfam PF00108 Thiolase, N-terminal domain 15 281 3.3E-47 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS16955 a628f180921583ad24fc98e1518cc878 253 SMART SM00382 27 226 1.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16955 a628f180921583ad24fc98e1518cc878 253 Gene3D G3DSA:3.40.50.300 1 253 1.4E-64 T 28-03-2018 hmeg3_RS16955 a628f180921583ad24fc98e1518cc878 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 2.7E-12 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS16955 a628f180921583ad24fc98e1518cc878 253 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16955 a628f180921583ad24fc98e1518cc878 253 Pfam PF00005 ABC transporter 18 179 5.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16955 a628f180921583ad24fc98e1518cc878 253 SUPERFAMILY SSF52540 2 250 2.0E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17970 f0afe7035fe961f0cc5fcf9e9fcc31bb 220 SUPERFAMILY SSF52540 8 217 8.07E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17970 f0afe7035fe961f0cc5fcf9e9fcc31bb 220 Hamap MF_00238 Cytidylate kinase [cmk]. 7 220 31.715 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 hmeg3_RS17970 f0afe7035fe961f0cc5fcf9e9fcc31bb 220 Pfam PF02224 Cytidylate kinase 9 215 5.0E-72 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 hmeg3_RS17970 f0afe7035fe961f0cc5fcf9e9fcc31bb 220 TIGRFAM TIGR00017 cmk: cytidylate kinase 7 215 3.5E-71 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 hmeg3_RS17970 f0afe7035fe961f0cc5fcf9e9fcc31bb 220 Gene3D G3DSA:3.40.50.300 5 220 1.9E-44 T 28-03-2018 hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 Gene3D G3DSA:3.90.76.10 86 183 2.0E-21 T 28-03-2018 hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 516 9.3E-81 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 SUPERFAMILY SSF53850 47 367 7.78E-113 T 28-03-2018 hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 SUPERFAMILY SSF53850 400 603 7.78E-113 T 28-03-2018 hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 Gene3D G3DSA:3.10.105.10 333 571 4.0E-47 T 28-03-2018 hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 PIRSF PIRSF002741 1 602 1.5E-100 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS06990 89625e62f6bc03e017ae7a76fab585de 605 Gene3D G3DSA:3.40.190.10 184 332 3.0E-30 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 SUPERFAMILY SSF52540 312 586 1.08E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 9.9E-98 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 PIRSF PIRSF001174 1 775 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 TIGRFAM TIGR00763 lon: endopeptidase La 13 771 6.4E-300 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 1.5E-55 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 1.5E-55 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 1.5E-55 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 1.5E-55 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 1.5E-55 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Gene3D G3DSA:2.30.130.40 1 119 5.3E-32 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 1.3E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 SMART SM00382 348 492 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Gene3D G3DSA:3.40.50.300 288 504 9.0E-31 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Hamap MF_01973 Lon protease [lon]. 12 772 71.585 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 SUPERFAMILY SSF54211 595 770 3.49E-60 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Gene3D G3DSA:1.10.8.60 505 576 6.9E-35 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 SUPERFAMILY SSF88697 11 202 1.12E-52 T 28-03-2018 IPR015947 PUA-like domain hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 12 199 4.8E-42 T 28-03-2018 IPR003111 Lon, substrate-binding domain hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Gene3D G3DSA:1.10.4060.10 123 212 4.6E-30 T 28-03-2018 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 SMART SM00464 11 203 3.6E-71 T 28-03-2018 IPR003111 Lon, substrate-binding domain hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 hmeg3_RS10460 af7ea4f0dffb1175c923aca03ed6da6b 802 Gene3D G3DSA:3.30.230.10 577 794 4.7E-69 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS13895 1dbc428659f6cdb84ef0364a8f207fa7 307 Pfam PF00294 pfkB family carbohydrate kinase 3 294 5.3E-52 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB hmeg3_RS13895 1dbc428659f6cdb84ef0364a8f207fa7 307 Gene3D G3DSA:3.40.1190.20 1 305 4.6E-66 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS13895 1dbc428659f6cdb84ef0364a8f207fa7 307 SUPERFAMILY SSF53613 2 300 3.74E-80 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS09990 107d6a1021e38f484e1b21c575029481 154 SUPERFAMILY SSF54637 6 147 6.28E-48 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS09990 107d6a1021e38f484e1b21c575029481 154 Gene3D G3DSA:3.10.129.10 1 152 2.6E-56 T 28-03-2018 hmeg3_RS09990 107d6a1021e38f484e1b21c575029481 154 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 4 143 4.7E-61 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 hmeg3_RS09990 107d6a1021e38f484e1b21c575029481 154 Pfam PF07977 FabA-like domain 13 137 5.6E-39 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 hmeg3_RS09990 107d6a1021e38f484e1b21c575029481 154 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 4 146 34.495 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 hmeg3_RS21235 262948a2ce70f452e80f16abf83a382e 343 TIGRFAM TIGR04440 glyco_TIGR04440: glycosyltransferase domain 4 221 1.4E-36 T 28-03-2018 IPR031042 Glycosyltransferase domain hmeg3_RS21235 262948a2ce70f452e80f16abf83a382e 343 SUPERFAMILY SSF53448 2 164 5.38E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21235 262948a2ce70f452e80f16abf83a382e 343 Pfam PF00535 Glycosyl transferase family 2 6 118 1.7E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS21235 262948a2ce70f452e80f16abf83a382e 343 Gene3D G3DSA:3.90.550.10 1 247 1.4E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS03415 bc954a12e2d5d1b7d415527290602b37 421 Gene3D G3DSA:1.20.1250.20 26 225 3.1E-32 T 28-03-2018 hmeg3_RS03415 bc954a12e2d5d1b7d415527290602b37 421 Pfam PF07690 Major Facilitator Superfamily 43 257 2.9E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS03415 bc954a12e2d5d1b7d415527290602b37 421 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 35 411 3.5E-96 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 hmeg3_RS03415 bc954a12e2d5d1b7d415527290602b37 421 SUPERFAMILY SSF103473 30 417 1.02E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS03415 bc954a12e2d5d1b7d415527290602b37 421 Gene3D G3DSA:1.20.1250.20 226 421 8.9E-15 T 28-03-2018 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 SMART SM00382 362 548 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 SUPERFAMILY SSF52540 329 573 1.52E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 8 574 1.2E-221 T 28-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 Gene3D G3DSA:3.40.50.300 322 578 7.7E-75 T 28-03-2018 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 Pfam PF00005 ABC transporter 353 502 6.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 SUPERFAMILY SSF90123 8 317 9.16E-74 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 Gene3D G3DSA:1.20.1560.10 4 321 1.0E-63 T 28-03-2018 hmeg3_RS18900 747e5bca1f14b5d26d19116c7077c97f 578 Pfam PF00664 ABC transporter transmembrane region 22 292 1.6E-51 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS20875 b803c11b3ff5431dcadab453fdb8784e 290 Pfam PF02673 Bacitracin resistance protein BacA 23 278 8.2E-72 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 hmeg3_RS20875 b803c11b3ff5431dcadab453fdb8784e 290 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 16 284 16.118 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 hmeg3_RS20875 b803c11b3ff5431dcadab453fdb8784e 290 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 24 277 4.5E-67 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 hmeg3_RS19285 294d309d7ee2c08f632640eac4893b07 208 SMART SM00903 19 169 3.4E-16 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS19285 294d309d7ee2c08f632640eac4893b07 208 SUPERFAMILY SSF50475 1 193 6.38E-43 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS19285 294d309d7ee2c08f632640eac4893b07 208 Pfam PF01613 Flavin reductase like domain 22 165 4.4E-15 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS19285 294d309d7ee2c08f632640eac4893b07 208 Gene3D G3DSA:2.30.110.10 15 208 2.7E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS06680 2d2f9a253aaee2f94e59d48f9867be67 358 Pfam PF00581 Rhodanese-like domain 265 348 2.5E-6 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS06680 2d2f9a253aaee2f94e59d48f9867be67 358 Gene3D G3DSA:3.40.50.720 5 245 1.0E-63 T 28-03-2018 hmeg3_RS06680 2d2f9a253aaee2f94e59d48f9867be67 358 SMART SM00450 260 355 3.7E-6 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS06680 2d2f9a253aaee2f94e59d48f9867be67 358 Gene3D G3DSA:3.40.250.10 246 352 2.2E-13 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS06680 2d2f9a253aaee2f94e59d48f9867be67 358 Pfam PF00899 ThiF family 11 245 4.0E-58 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 hmeg3_RS06680 2d2f9a253aaee2f94e59d48f9867be67 358 SUPERFAMILY SSF69572 10 326 1.57E-81 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 5.0E-52 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 35.109 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 Pfam PF00547 Urease, gamma subunit 1 99 7.8E-48 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 4.0E-42 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 Gene3D G3DSA:3.30.280.10 2 99 4.8E-48 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 SUPERFAMILY SSF54111 1 99 2.62E-46 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00300 acec679278c0a587f29a34d3f92a9f20 100 PIRSF PIRSF001223 1 100 1.3E-51 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS22445 0bb1cef41cf576afa424071cad02a734 249 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 16 210 21.316 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 hmeg3_RS22445 0bb1cef41cf576afa424071cad02a734 249 Gene3D G3DSA:3.10.300.10 10 212 5.9E-40 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 hmeg3_RS22445 0bb1cef41cf576afa424071cad02a734 249 SUPERFAMILY SSF50486 12 216 4.79E-49 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 hmeg3_RS22445 0bb1cef41cf576afa424071cad02a734 249 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 18 202 3.3E-34 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 hmeg3_RS09285 d9d2692f14ea5807a7c89d8d63137f95 201 Pfam PF04973 Nicotinamide mononucleotide transporter 17 194 1.3E-52 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 hmeg3_RS09285 d9d2692f14ea5807a7c89d8d63137f95 201 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 17 194 2.5E-22 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 38 126 3.2E-25 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 SUPERFAMILY SSF54675 22 127 2.59E-31 T 28-03-2018 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 128 291 2.8E-52 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 SUPERFAMILY SSF51690 128 293 6.67E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 PIRSF PIRSF006250 21 295 4.9E-91 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 Gene3D G3DSA:3.20.20.70 154 283 2.6E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 30 293 1.8E-89 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 hmeg3_RS10150 e6297a124c81b3359f1aacfb6bb96845 295 Gene3D G3DSA:3.90.1170.20 18 153 3.2E-44 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:3.30.70.1320 777 854 2.8E-7 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:3.30.70.1430 40 142 3.6E-26 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:3.30.70.1430 589 678 2.6E-17 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82714 185 273 3.4E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82693 277 333 1.62E-26 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82693 139 184 1.62E-26 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82866 841 1036 1.57E-43 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:3.30.2090.10 186 275 6.2E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82866 299 499 2.75E-51 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82693 41 134 2.93E-26 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:1.20.1640.10 519 588 0.18 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:1.20.1640.10 280 501 1.8E-50 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:1.20.1640.10 855 1038 5.7E-40 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 Gene3D G3DSA:3.30.70.1440 682 776 1.2E-20 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.3E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1051 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82714 732 818 6.28E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82693 818 867 4.97E-25 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82693 682 731 4.97E-25 T 28-03-2018 hmeg3_RS22160 c03ca01d500bc00f1842130a329b1b45 1070 SUPERFAMILY SSF82693 575 681 9.42E-26 T 28-03-2018 hmeg3_RS06175 6d3881b3c1c3fb09f90115333cb76470 349 SUPERFAMILY SSF53850 28 338 2.31E-96 T 28-03-2018 hmeg3_RS06175 6d3881b3c1c3fb09f90115333cb76470 349 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 338 4.2E-118 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 hmeg3_RS06175 6d3881b3c1c3fb09f90115333cb76470 349 Gene3D G3DSA:3.40.190.10 28 192 1.5E-31 T 28-03-2018 hmeg3_RS06175 6d3881b3c1c3fb09f90115333cb76470 349 Pfam PF12849 PBP superfamily domain 21 310 5.4E-63 T 28-03-2018 IPR024370 PBP domain hmeg3_RS06175 6d3881b3c1c3fb09f90115333cb76470 349 PIRSF PIRSF002756 5 341 3.3E-103 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 hmeg3_RS06175 6d3881b3c1c3fb09f90115333cb76470 349 Gene3D G3DSA:3.40.190.10 195 349 1.7E-24 T 28-03-2018 hmeg3_RS17245 55ecfb52738cc01f3094fe6c31818463 215 Pfam PF00694 Aconitase C-terminal domain 1 132 5.2E-38 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS17245 55ecfb52738cc01f3094fe6c31818463 215 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 211 44.3 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 hmeg3_RS17245 55ecfb52738cc01f3094fe6c31818463 215 SUPERFAMILY SSF52016 1 201 3.14E-63 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS17245 55ecfb52738cc01f3094fe6c31818463 215 Gene3D G3DSA:3.20.19.10 1 185 7.6E-48 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS17245 55ecfb52738cc01f3094fe6c31818463 215 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 197 1.2E-83 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 hmeg3_RS03630 411409c1eec9f910e7861a067c1d1210 285 Gene3D G3DSA:1.10.3210.10 2 278 1.3E-45 T 28-03-2018 hmeg3_RS03630 411409c1eec9f910e7861a067c1d1210 285 Pfam PF08668 HDOD domain 16 203 5.0E-58 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS03630 411409c1eec9f910e7861a067c1d1210 285 SMART SM00471 106 240 9.7E-6 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS03630 411409c1eec9f910e7861a067c1d1210 285 SUPERFAMILY SSF109604 9 272 1.11E-64 T 28-03-2018 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 SUPERFAMILY SSF54980 292 370 2.52E-17 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 TIGRFAM TIGR01393 lepA: elongation factor 4 3 597 1.4E-296 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 174 1.6E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Gene3D G3DSA:3.30.70.240 392 551 2.7E-27 T 28-03-2018 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Pfam PF03144 Elongation factor Tu domain 2 205 275 8.1E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 SUPERFAMILY SSF52540 2 205 3.43E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 SUPERFAMILY SSF54980 401 495 3.41E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Gene3D G3DSA:3.40.50.300 1 190 5.1E-36 T 28-03-2018 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 SMART SM00838 403 488 0.0061 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Hamap MF_00071 Elongation factor 4 [lepA]. 1 599 303.692 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Gene3D G3DSA:2.40.30.10 191 287 1.1E-22 T 28-03-2018 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Pfam PF06421 GTP-binding protein LepA C-terminus 489 595 2.3E-47 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Pfam PF00679 Elongation factor G C-terminus 401 485 1.3E-22 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 5.2E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 Gene3D G3DSA:3.30.70.870 288 367 1.4E-27 T 28-03-2018 hmeg3_RS16690 1344db54503d273ec13af6a763b520eb 599 SUPERFAMILY SSF50447 165 288 3.53E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 SMART SM00342 244 327 2.8E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 Pfam PF12833 Helix-turn-helix domain 250 328 2.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 SUPERFAMILY SSF46689 280 329 3.26E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 SUPERFAMILY SSF52317 13 209 5.24E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 Pfam PF01965 DJ-1/PfpI family 13 189 1.9E-14 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 SUPERFAMILY SSF46689 228 278 8.36E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 Gene3D G3DSA:1.10.10.60 225 277 5.7E-12 T 28-03-2018 hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 Gene3D G3DSA:3.40.50.880 7 224 3.0E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS09195 845adb3ef5ebb2bdeb6100f79ce0c309 335 Gene3D G3DSA:1.10.10.60 278 334 3.3E-8 T 28-03-2018 hmeg3_RS09715 eb1c5c161bb35e5a002b88b4746cf3db 341 Pfam PF01738 Dienelactone hydrolase family 80 259 3.8E-14 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS09715 eb1c5c161bb35e5a002b88b4746cf3db 341 SUPERFAMILY SSF53474 71 260 6.83E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09715 eb1c5c161bb35e5a002b88b4746cf3db 341 Gene3D G3DSA:3.40.50.1820 3 273 9.0E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00895 9ddb79a6b14285db756d69327577cb7f 208 SUPERFAMILY SSF52833 5 90 2.95E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS00895 9ddb79a6b14285db756d69327577cb7f 208 Gene3D G3DSA:3.40.30.10 1 98 8.7E-32 T 28-03-2018 hmeg3_RS00895 9ddb79a6b14285db756d69327577cb7f 208 Pfam PF00043 Glutathione S-transferase, C-terminal domain 128 194 3.9E-9 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS00895 9ddb79a6b14285db756d69327577cb7f 208 Gene3D G3DSA:1.20.1050.10 99 195 1.1E-19 T 28-03-2018 hmeg3_RS00895 9ddb79a6b14285db756d69327577cb7f 208 SUPERFAMILY SSF47616 77 200 2.73E-24 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS00895 9ddb79a6b14285db756d69327577cb7f 208 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 85 2.3E-16 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS23630 eccd23c72c3af64f0c549c4fe876097f 407 SUPERFAMILY SSF53756 6 398 4.55E-29 T 28-03-2018 hmeg3_RS23630 eccd23c72c3af64f0c549c4fe876097f 407 Pfam PF13524 Glycosyl transferases group 1 351 394 1.4E-5 T 28-03-2018 hmeg3_RS23630 eccd23c72c3af64f0c549c4fe876097f 407 Gene3D G3DSA:3.40.50.2000 150 383 1.1E-23 T 28-03-2018 hmeg3_RS18285 359f0569f45eb40ce6d80ebe76a89e27 255 SMART SM00382 30 229 5.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS18285 359f0569f45eb40ce6d80ebe76a89e27 255 SUPERFAMILY SSF52540 5 252 7.24E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18285 359f0569f45eb40ce6d80ebe76a89e27 255 Pfam PF00005 ABC transporter 21 181 3.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS18285 359f0569f45eb40ce6d80ebe76a89e27 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 252 1.4E-10 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS18285 359f0569f45eb40ce6d80ebe76a89e27 255 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS18285 359f0569f45eb40ce6d80ebe76a89e27 255 Gene3D G3DSA:3.40.50.300 1 254 5.2E-57 T 28-03-2018 hmeg3_RS22505 359f0569f45eb40ce6d80ebe76a89e27 255 SMART SM00382 30 229 5.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22505 359f0569f45eb40ce6d80ebe76a89e27 255 SUPERFAMILY SSF52540 5 252 7.24E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS22505 359f0569f45eb40ce6d80ebe76a89e27 255 Pfam PF00005 ABC transporter 21 181 3.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS22505 359f0569f45eb40ce6d80ebe76a89e27 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 252 1.4E-10 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS22505 359f0569f45eb40ce6d80ebe76a89e27 255 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS22505 359f0569f45eb40ce6d80ebe76a89e27 255 Gene3D G3DSA:3.40.50.300 1 254 5.2E-57 T 28-03-2018 hmeg3_RS02505 895bf52bc0a46186e6503111c63d6cd1 236 SUPERFAMILY SSF52833 26 189 4.22E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02505 895bf52bc0a46186e6503111c63d6cd1 236 Gene3D G3DSA:3.40.30.10 23 229 8.3E-41 T 28-03-2018 hmeg3_RS02505 895bf52bc0a46186e6503111c63d6cd1 236 Pfam PF01323 DSBA-like thioredoxin domain 96 184 2.8E-14 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 hmeg3_RS02505 895bf52bc0a46186e6503111c63d6cd1 236 PIRSF PIRSF001488 4 216 5.5E-47 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL hmeg3_RS01210 43082b8e0c454282b0106913d51b1050 352 Gene3D G3DSA:2.102.10.10 2 106 4.4E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01210 43082b8e0c454282b0106913d51b1050 352 Gene3D G3DSA:3.90.380.10 107 348 1.1E-46 T 28-03-2018 hmeg3_RS01210 43082b8e0c454282b0106913d51b1050 352 SUPERFAMILY SSF55961 102 345 7.54E-56 T 28-03-2018 hmeg3_RS01210 43082b8e0c454282b0106913d51b1050 352 Pfam PF00355 Rieske [2Fe-2S] domain 6 86 2.0E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01210 43082b8e0c454282b0106913d51b1050 352 SUPERFAMILY SSF50022 3 111 6.29E-32 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01210 43082b8e0c454282b0106913d51b1050 352 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 47 69 - T 28-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 SUPERFAMILY SSF56322 31 400 1.83E-98 T 28-03-2018 IPR005801 ADC synthase GO:0009058 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 Pfam PF01063 Amino-transferase class IV 407 607 2.3E-36 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 SUPERFAMILY SSF56752 347 606 1.11E-47 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 60 398 1.8E-103 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 PRINTS PR00095 Anthranilate synthase component I signature 231 244 1.3E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 PRINTS PR00095 Anthranilate synthase component I signature 245 258 1.3E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 PRINTS PR00095 Anthranilate synthase component I signature 325 339 1.3E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 Gene3D G3DSA:3.60.120.10 1 397 6.1E-120 T 28-03-2018 IPR005801 ADC synthase GO:0009058 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 Gene3D G3DSA:3.30.470.10 398 479 6.4E-19 T 28-03-2018 hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 Pfam PF00425 chorismate binding enzyme 129 394 3.3E-81 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal hmeg3_RS15945 c81c4468a9ebfc6c3a7bdce77bfd891c 615 Gene3D G3DSA:3.20.10.10 480 612 5.5E-29 T 28-03-2018 hmeg3_RS13255 bace524c1b34c1dc1ead45ad5503f09a 194 Gene3D G3DSA:3.90.950.10 1 194 2.6E-74 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like hmeg3_RS13255 bace524c1b34c1dc1ead45ad5503f09a 194 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 193 1.7E-50 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 hmeg3_RS13255 bace524c1b34c1dc1ead45ad5503f09a 194 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 3 194 46.191 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 hmeg3_RS13255 bace524c1b34c1dc1ead45ad5503f09a 194 Pfam PF01725 Ham1 family 5 191 7.3E-53 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 hmeg3_RS13255 bace524c1b34c1dc1ead45ad5503f09a 194 SUPERFAMILY SSF52972 2 193 1.2E-68 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like hmeg3_RS08425 b3f31b408055fb4a51d0dfad2065736e 314 SUPERFAMILY SSF88713 206 287 7.23E-20 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS08425 b3f31b408055fb4a51d0dfad2065736e 314 SUPERFAMILY SSF88713 4 38 7.23E-20 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS08425 b3f31b408055fb4a51d0dfad2065736e 314 SUPERFAMILY SSF88713 86 170 7.23E-20 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS08425 b3f31b408055fb4a51d0dfad2065736e 314 Pfam PF01522 Polysaccharide deacetylase 15 170 1.5E-5 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 hmeg3_RS08425 b3f31b408055fb4a51d0dfad2065736e 314 Gene3D G3DSA:3.20.20.370 2 293 5.2E-21 T 28-03-2018 hmeg3_RS15535 10d768cdfdf7f9cc05d63f04bc8c5988 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 106 1.5E-37 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 hmeg3_RS15535 10d768cdfdf7f9cc05d63f04bc8c5988 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 5.1E-26 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 hmeg3_RS15535 10d768cdfdf7f9cc05d63f04bc8c5988 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 hmeg3_RS15535 10d768cdfdf7f9cc05d63f04bc8c5988 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 4.9E-52 T 28-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 hmeg3_RS15535 10d768cdfdf7f9cc05d63f04bc8c5988 107 Gene3D G3DSA:2.60.300.12 2 107 5.6E-38 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 hmeg3_RS15535 10d768cdfdf7f9cc05d63f04bc8c5988 107 SUPERFAMILY SSF89360 1 96 2.49E-32 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 Gene3D G3DSA:1.10.1660.10 56 135 2.5E-20 T 28-03-2018 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 SUPERFAMILY SSF46955 1 126 8.42E-39 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 SMART SM00422 1 70 7.4E-32 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 Pfam PF09278 MerR, DNA binding 45 108 1.4E-18 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 Pfam PF00376 MerR family regulatory protein 2 39 1.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.0E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.0E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.0E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 2.0E-50 T 28-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 hmeg3_RS14675 dff2e0a6fb7a58823cded2328bf6cbe8 136 Gene3D G3DSA:1.10.1660.10 1 55 1.1E-21 T 28-03-2018 hmeg3_RS21780 5436bd9b899bfc927cf04f243eb03197 184 PIRSF PIRSF000239 24 184 3.8E-19 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS21780 5436bd9b899bfc927cf04f243eb03197 184 Gene3D G3DSA:3.40.30.10 20 179 5.3E-31 T 28-03-2018 hmeg3_RS21780 5436bd9b899bfc927cf04f243eb03197 184 SUPERFAMILY SSF52833 27 179 1.1E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS21780 5436bd9b899bfc927cf04f243eb03197 184 Pfam PF00578 AhpC/TSA family 31 158 2.8E-26 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 SUPERFAMILY SSF46785 34 117 3.69E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 Gene3D G3DSA:1.10.10.10 28 117 5.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 SUPERFAMILY SSF53850 118 323 6.88E-39 T 28-03-2018 hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 34 92 1.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 Gene3D G3DSA:3.40.190.10 118 205 1.4E-10 T 28-03-2018 hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 Gene3D G3DSA:3.40.190.10 206 295 3.0E-27 T 28-03-2018 hmeg3_RS13545 33b475c0de092dd7b862155fc739bbce 325 Pfam PF03466 LysR substrate binding domain 118 321 1.7E-39 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 SMART SM00421 151 208 1.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 Pfam PF00072 Response regulator receiver domain 7 120 1.6E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 2.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 Gene3D G3DSA:3.40.50.2300 4 130 2.5E-19 T 28-03-2018 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 5.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 5.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 5.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 SMART SM00448 5 120 3.5E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 SUPERFAMILY SSF46894 143 214 2.31E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 SUPERFAMILY SSF52172 4 134 7.26E-20 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15705 20aae8bfce889500c07fbc865ea02b5e 222 Gene3D G3DSA:1.10.10.10 131 218 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 Gene3D G3DSA:3.40.50.980 202 402 4.9E-40 T 28-03-2018 hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 SUPERFAMILY SSF56801 10 299 4.84E-111 T 28-03-2018 hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 SUPERFAMILY SSF56801 352 616 4.84E-111 T 28-03-2018 hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 Gene3D G3DSA:3.30.300.30 477 618 1.7E-6 T 28-03-2018 hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 Pfam PF00501 AMP-binding enzyme 20 479 6.0E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 Gene3D G3DSA:3.40.50.980 8 201 4.2E-37 T 28-03-2018 hmeg3_RS10540 bc96601990618d22712b6bf2e02eaab2 657 Gene3D G3DSA:2.30.38.10 403 475 1.2E-18 T 28-03-2018 hmeg3_RS11065 82f7186cafd41ef61fa2c0030a94f8a7 182 Gene3D G3DSA:1.20.120.620 28 127 7.9E-10 T 28-03-2018 hmeg3_RS11065 82f7186cafd41ef61fa2c0030a94f8a7 182 Pfam PF13493 Domain of unknown function (DUF4118) 30 132 4.8E-8 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain hmeg3_RS12765 a457fe1cbc0b823212e8007d3a0b453d 197 SUPERFAMILY SSF109604 6 185 2.71E-43 T 28-03-2018 hmeg3_RS12765 a457fe1cbc0b823212e8007d3a0b453d 197 Pfam PF13023 HD domain 16 179 1.5E-46 T 28-03-2018 IPR006674 HD domain hmeg3_RS12765 a457fe1cbc0b823212e8007d3a0b453d 197 Gene3D G3DSA:1.10.3210.10 1 195 3.7E-45 T 28-03-2018 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 290 61.035 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 1.3E-68 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 1.3E-68 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 1.3E-68 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 1.3E-68 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 1.3E-68 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 250 266 1.3E-68 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 289 1.2E-149 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 296 1.4E-158 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 SUPERFAMILY SSF55681 3 289 1.77E-132 T 28-03-2018 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 Gene3D G3DSA:3.30.930.10 1 213 1.8E-88 T 28-03-2018 hmeg3_RS19850 5f76f3c49e3bd1b7f7a6286a668554ae 306 Gene3D G3DSA:1.20.58.180 215 291 8.1E-34 T 28-03-2018 hmeg3_RS16550 5159f6264641cebfc212eee9d405af7c 134 SMART SM00448 5 121 6.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS16550 5159f6264641cebfc212eee9d405af7c 134 Pfam PF00072 Response regulator receiver domain 8 122 1.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS16550 5159f6264641cebfc212eee9d405af7c 134 SUPERFAMILY SSF52172 8 129 1.71E-33 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS16550 5159f6264641cebfc212eee9d405af7c 134 Gene3D G3DSA:3.40.50.2300 4 133 1.2E-33 T 28-03-2018 hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 Gene3D G3DSA:1.20.120.530 73 212 2.5E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 Pfam PF07729 FCD domain 80 201 1.2E-18 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 SMART SM00345 12 70 1.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 Gene3D G3DSA:1.10.10.10 1 72 3.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 SMART SM00895 80 202 5.5E-16 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 SUPERFAMILY SSF46785 6 87 1.17E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 70 1.2E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03095 cf283ccfdfaed8010e4dffb186b9ef5b 266 SUPERFAMILY SSF48008 75 207 6.28E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 SMART SM00342 266 348 6.7E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 Pfam PF12833 Helix-turn-helix domain 277 349 3.8E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 317 332 4.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 332 348 4.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 SUPERFAMILY SSF46689 300 349 2.69E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 Gene3D G3DSA:1.10.10.60 235 291 0.0073 T 28-03-2018 hmeg3_RS23390 b28d2dcb5b42daecba496746ec2c96b2 357 Gene3D G3DSA:1.10.10.60 299 350 1.5E-12 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 1.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82714 723 807 3.53E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82693 46 126 2.88E-19 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1043 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82866 806 1042 7.06E-44 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Gene3D G3DSA:3.30.2090.10 721 809 9.3E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Gene3D G3DSA:3.30.2090.10 183 271 4.4E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82866 294 505 8.89E-38 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82714 185 270 7.46E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Gene3D G3DSA:3.30.70.1430 567 665 4.0E-9 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Pfam PF00873 AcrB/AcrD/AcrF family 6 1036 1.3E-237 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Gene3D G3DSA:1.20.1640.10 826 1046 3.0E-26 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Gene3D G3DSA:1.20.1640.10 288 517 3.8E-43 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82693 271 328 4.97E-22 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 SUPERFAMILY SSF82693 137 184 4.97E-22 T 28-03-2018 hmeg3_RS14775 c27bd2f9e0a0c956a7c3729236ec8841 1046 Gene3D G3DSA:3.30.70.1430 45 137 2.9E-18 T 28-03-2018 hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 ProSitePatterns PS00194 Thioredoxin family active site. 130 148 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 SUPERFAMILY SSF52833 105 245 1.5E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 Pfam PF10411 Disulfide bond isomerase protein N-terminus 41 93 3.9E-18 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 SUPERFAMILY SSF54423 37 92 1.61E-11 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 Gene3D G3DSA:3.40.30.10 113 249 2.2E-19 T 28-03-2018 hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 Pfam PF13098 Thioredoxin-like domain 122 244 1.4E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03145 98b897237ee9e806217cc4b558a327d3 249 Gene3D G3DSA:3.10.450.70 32 95 2.0E-19 T 28-03-2018 hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 Gene3D G3DSA:2.160.10.10 92 262 2.4E-34 T 28-03-2018 hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 71 4.9E-25 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 Gene3D G3DSA:1.10.166.10 4 71 4.6E-27 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 277 55.317 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 171 0.0013 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 SUPERFAMILY SSF51161 4 261 5.54E-69 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 180 214 4.4E-14 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09860 e7ba1fe3ad9b79d065d9ac658ee1a25e 278 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 277 2.5E-139 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 SMART SM00437 279 560 5.2E-73 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 331 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Gene3D G3DSA:3.40.50.140 3 154 3.9E-35 T 28-03-2018 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Gene3D G3DSA:1.10.460.10 486 620 3.0E-20 T 28-03-2018 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Gene3D G3DSA:1.10.460.10 159 359 1.1E-38 T 28-03-2018 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 7.9E-27 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 7.9E-27 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 322 331 7.9E-27 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 404 420 7.9E-27 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 523 537 7.9E-27 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 SUPERFAMILY SSF56712 3 613 8.89E-175 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Pfam PF01131 DNA topoisomerase 156 598 1.6E-118 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Pfam PF01751 Toprim domain 4 132 6.5E-11 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Gene3D G3DSA:2.70.20.10 367 485 7.8E-25 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 SMART SM00436 126 221 1.5E-23 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 636 1.3E-174 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Pfam PF13342 C-terminal repeat of topoisomerase 762 821 4.0E-16 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 Pfam PF13342 C-terminal repeat of topoisomerase 649 713 1.9E-20 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat hmeg3_RS00645 4989a772b74912f941afe8ef3a3b9218 883 SMART SM00493 3 126 4.4E-11 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS18700 bffd6a2c62b55aedf6c944f448b7867e 151 Gene3D G3DSA:3.40.630.30 16 151 6.9E-20 T 28-03-2018 hmeg3_RS18700 bffd6a2c62b55aedf6c944f448b7867e 151 SUPERFAMILY SSF55729 11 143 5.98E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS18700 bffd6a2c62b55aedf6c944f448b7867e 151 Pfam PF13508 Acetyltransferase (GNAT) domain 65 135 2.5E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS20360 c1b7e2e860540fdc0bde2a9496089a23 115 PIRSF PIRSF021239 3 115 1.3E-52 T 28-03-2018 IPR007437 Putative member of DMT superfamily hmeg3_RS20360 c1b7e2e860540fdc0bde2a9496089a23 115 Pfam PF04342 Putative member of DMT superfamily (DUF486) 9 113 3.2E-46 T 28-03-2018 IPR007437 Putative member of DMT superfamily hmeg3_RS08905 51d62f7ec5ebdc417d7311f1be10c6f2 440 SMART SM00244 106 279 4.7E-19 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS08905 51d62f7ec5ebdc417d7311f1be10c6f2 440 SUPERFAMILY SSF117892 170 286 1.96E-19 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS08905 51d62f7ec5ebdc417d7311f1be10c6f2 440 Pfam PF01145 SPFH domain / Band 7 family 110 294 1.8E-27 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS08905 51d62f7ec5ebdc417d7311f1be10c6f2 440 Pfam PF12221 Bacterial membrane protein N terminal 13 67 3.2E-10 T 28-03-2018 IPR020980 Menbrane protein HflK, N-terminal hmeg3_RS08905 51d62f7ec5ebdc417d7311f1be10c6f2 440 TIGRFAM TIGR01933 hflK: HflK protein 108 381 6.6E-92 T 28-03-2018 IPR010201 HflK GO:0016021 hmeg3_RS20395 7800c3ca77120b6035c5635d7f2c60a2 368 TIGRFAM TIGR00109 hemH: ferrochelatase 16 330 2.0E-95 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 hmeg3_RS20395 7800c3ca77120b6035c5635d7f2c60a2 368 Pfam PF00762 Ferrochelatase 17 332 2.3E-115 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 hmeg3_RS20395 7800c3ca77120b6035c5635d7f2c60a2 368 SUPERFAMILY SSF53800 16 341 1.57E-107 T 28-03-2018 hmeg3_RS20395 7800c3ca77120b6035c5635d7f2c60a2 368 Gene3D G3DSA:3.40.50.1400 13 187 7.5E-54 T 28-03-2018 hmeg3_RS20395 7800c3ca77120b6035c5635d7f2c60a2 368 Gene3D G3DSA:3.40.50.1400 188 314 1.1E-42 T 28-03-2018 hmeg3_RS20395 7800c3ca77120b6035c5635d7f2c60a2 368 Hamap MF_00323 Ferrochelatase [hemH]. 15 335 36.788 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 hmeg3_RS14390 96cf4b58575e0e03015b3563b26d8201 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 281 6.8E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14390 96cf4b58575e0e03015b3563b26d8201 287 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 14 276 1.1E-98 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 hmeg3_RS14390 96cf4b58575e0e03015b3563b26d8201 287 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 17 280 1.2E-129 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 hmeg3_RS14390 96cf4b58575e0e03015b3563b26d8201 287 Gene3D G3DSA:1.10.3720.10 20 284 6.8E-46 T 28-03-2018 hmeg3_RS14390 96cf4b58575e0e03015b3563b26d8201 287 SUPERFAMILY SSF161098 22 274 7.46E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11935 6b135ba5dae27299e99e1320b3cc8ac5 347 Gene3D G3DSA:3.40.190.10 193 347 6.6E-25 T 28-03-2018 hmeg3_RS11935 6b135ba5dae27299e99e1320b3cc8ac5 347 Gene3D G3DSA:3.40.190.10 25 160 1.0E-32 T 28-03-2018 hmeg3_RS11935 6b135ba5dae27299e99e1320b3cc8ac5 347 SUPERFAMILY SSF53850 28 336 3.26E-96 T 28-03-2018 hmeg3_RS11935 6b135ba5dae27299e99e1320b3cc8ac5 347 PIRSF PIRSF002756 9 339 2.3E-102 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 hmeg3_RS11935 6b135ba5dae27299e99e1320b3cc8ac5 347 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 28 336 6.6E-120 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 hmeg3_RS11935 6b135ba5dae27299e99e1320b3cc8ac5 347 Pfam PF12849 PBP superfamily domain 27 308 8.1E-61 T 28-03-2018 IPR024370 PBP domain hmeg3_RS13940 fb36b2c6554f05d0c93f54e2e8337119 213 Gene3D G3DSA:2.70.70.10 55 110 0.0045 T 28-03-2018 hmeg3_RS13940 fb36b2c6554f05d0c93f54e2e8337119 213 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 9 213 37.133 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 hmeg3_RS13940 fb36b2c6554f05d0c93f54e2e8337119 213 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 9 212 2.2E-73 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 hmeg3_RS13940 fb36b2c6554f05d0c93f54e2e8337119 213 Pfam PF02666 Phosphatidylserine decarboxylase 43 210 2.5E-34 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 hmeg3_RS13940 fb36b2c6554f05d0c93f54e2e8337119 213 Gene3D G3DSA:2.40.50.100 111 211 3.8E-4 T 28-03-2018 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 SUPERFAMILY SSF56672 402 802 1.22E-111 T 28-03-2018 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 SMART SM00486 166 573 2.5E-68 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 433 446 1.9E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 507 519 1.9E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 559 567 1.9E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 Pfam PF03104 DNA polymerase family B, exonuclease domain 81 180 8.8E-6 T 28-03-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 Pfam PF03104 DNA polymerase family B, exonuclease domain 216 314 1.0E-7 T 28-03-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 ProSitePatterns PS00116 DNA polymerase family B signature. 561 569 - T 28-03-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 Gene3D G3DSA:3.30.420.10 169 365 2.1E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 Pfam PF00136 DNA polymerase family B 396 761 5.1E-41 T 28-03-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 Gene3D G3DSA:3.90.1600.10 410 619 1.3E-49 T 28-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10815 4ed68eb2e977348719a205b922248e35 806 SUPERFAMILY SSF53098 15 407 1.52E-95 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS14545 34bb5706545d8cb349bbe24ec07320de 328 Pfam PF04116 Fatty acid hydroxylase superfamily 135 278 5.4E-31 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF05594 Haemagluttinin repeat 746 807 0.046 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF05594 Haemagluttinin repeat 258 335 1.6E-4 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF05594 Haemagluttinin repeat 1543 1612 0.0094 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF05594 Haemagluttinin repeat 1810 1828 200.0 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF05594 Haemagluttinin repeat 873 967 12.0 T 28-03-2018 IPR008619 Filamentous haemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 SUPERFAMILY SSF54060 3240 3301 4.71E-5 T 28-03-2018 hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 530 558 0.25 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1550 1579 0.003 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 908 945 2.6E-5 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 851 885 1.9 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 355 383 0.36 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1775 1804 0.052 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 423 463 2.6E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 1590 1802 0.053 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 890 1039 6.1E-4 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 791 889 0.13 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 2032 2250 0.044 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF13930 DNA/RNA non-specific endonuclease 3202 3324 3.0E-25 T 28-03-2018 hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF04829 Pre-toxin domain with VENN motif 2897 2947 2.8E-12 T 28-03-2018 IPR006914 VENN motif-containing domain hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 415 496 1.7E-6 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 363 414 3.2E-5 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 497 587 0.0025 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 588 730 0.0022 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 731 790 5.8E-6 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Gene3D G3DSA:2.160.20.10 78 362 4.6E-60 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 25 2.8E-8 T 28-03-2018 IPR024973 ESPR domain hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 SMART SM00912 91 211 8.8E-47 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF05860 haemagglutination activity domain 78 209 8.1E-32 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 110 205 1.9E-21 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF13332 Haemagluttinin repeat 2073 2232 2.1E-15 T 28-03-2018 IPR025157 Hemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF13332 Haemagluttinin repeat 1939 2025 1.2E-7 T 28-03-2018 IPR025157 Hemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 Pfam PF13332 Haemagluttinin repeat 2390 2555 2.9E-35 T 28-03-2018 IPR025157 Hemagglutinin repeat hmeg3_RS23815 b1fce3eca0c57a6181dc0b8b866f375e 3335 SUPERFAMILY SSF51126 81 351 2.26E-64 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor hmeg3_RS23380 020221dbfa4b105a9791d9f63eef9306 744 SUPERFAMILY SSF53659 5 743 0.0 T 28-03-2018 hmeg3_RS23380 020221dbfa4b105a9791d9f63eef9306 744 PIRSF PIRSF009407 1 744 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 hmeg3_RS23380 020221dbfa4b105a9791d9f63eef9306 744 Gene3D G3DSA:3.40.718.10 422 717 7.6E-42 T 28-03-2018 hmeg3_RS23380 020221dbfa4b105a9791d9f63eef9306 744 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 hmeg3_RS23380 020221dbfa4b105a9791d9f63eef9306 744 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 744 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 hmeg3_RS23380 020221dbfa4b105a9791d9f63eef9306 744 Gene3D G3DSA:3.40.718.10 73 368 4.1E-45 T 28-03-2018 hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 Gene3D G3DSA:3.40.50.720 1 240 8.0E-51 T 28-03-2018 hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 237 8.2E-46 T 28-03-2018 hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.8E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 8.8E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.8E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.8E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.8E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.8E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 7.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01530 4f372057294725bb657c80710bfe4f49 240 SUPERFAMILY SSF51735 11 237 2.59E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 SUPERFAMILY SSF53850 113 327 4.89E-34 T 28-03-2018 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 86 9.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 Gene3D G3DSA:3.40.190.10 208 292 3.6E-12 T 28-03-2018 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 Gene3D G3DSA:1.10.10.10 21 108 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 Gene3D G3DSA:3.40.190.10 113 207 2.2E-20 T 28-03-2018 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 SUPERFAMILY SSF46785 25 136 4.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 64 2.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 75 2.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19540 e89fdbe4338f227a4e64f8fdefd64631 328 Pfam PF03466 LysR substrate binding domain 112 325 3.6E-31 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 Gene3D G3DSA:3.40.50.1100 118 218 1.6E-13 T 28-03-2018 hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 96 339 9.4E-11 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 TIGRFAM TIGR00260 thrC: threonine synthase 108 446 6.8E-70 T 28-03-2018 IPR004450 Threonine synthase-like hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 SUPERFAMILY SSF53686 1 484 1.38E-146 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 Gene3D G3DSA:3.90.1380.10 1 89 6.6E-32 T 28-03-2018 IPR029144 Threonine synthase, N-terminal hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 Gene3D G3DSA:3.40.50.1100 219 452 6.5E-80 T 28-03-2018 hmeg3_RS08480 df15839f0f12cc19ac5af417dcb23111 486 Pfam PF14821 Threonine synthase N terminus 2 79 2.0E-29 T 28-03-2018 IPR029144 Threonine synthase, N-terminal hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 SUPERFAMILY SSF51735 2 161 3.26E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 SUPERFAMILY SSF48179 163 291 1.93E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 PIRSF PIRSF000103 1 292 1.5E-71 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 Gene3D G3DSA:3.40.50.720 1 162 5.9E-35 T 28-03-2018 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 283 4.5E-37 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 6.0E-49 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 Gene3D G3DSA:1.10.1040.10 163 290 5.3E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS17045 22776f0c2810999c28e6c1c85465a2b2 295 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 3 292 1.1E-127 T 28-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 hmeg3_RS21610 0306af85f9384bc90965dc6ee1f34a24 378 SUPERFAMILY SSF53822 31 372 5.18E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS21610 0306af85f9384bc90965dc6ee1f34a24 378 Pfam PF13458 Periplasmic binding protein 35 362 2.8E-39 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS21610 0306af85f9384bc90965dc6ee1f34a24 378 Gene3D G3DSA:3.40.50.2300 201 359 2.0E-23 T 28-03-2018 hmeg3_RS21610 0306af85f9384bc90965dc6ee1f34a24 378 Gene3D G3DSA:3.40.50.2300 28 200 1.8E-20 T 28-03-2018 hmeg3_RS12405 73afe1393965df20631037f254a2d3e5 273 Pfam PF11760 Cobalamin synthesis G N-terminal 56 135 2.0E-27 T 28-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 hmeg3_RS12405 73afe1393965df20631037f254a2d3e5 273 SUPERFAMILY SSF159672 15 134 3.01E-35 T 28-03-2018 hmeg3_RS12405 73afe1393965df20631037f254a2d3e5 273 SUPERFAMILY SSF159672 172 253 3.01E-35 T 28-03-2018 hmeg3_RS12405 73afe1393965df20631037f254a2d3e5 273 Pfam PF01890 Cobalamin synthesis G C-terminus 140 257 2.4E-32 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 hmeg3_RS12405 73afe1393965df20631037f254a2d3e5 273 Gene3D G3DSA:3.30.420.180 131 261 2.1E-36 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 hmeg3_RS05925 5e69a7c5360db1d712157c77f46d39ac 278 SUPERFAMILY SSF51556 10 278 2.85E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS05925 5e69a7c5360db1d712157c77f46d39ac 278 Pfam PF04909 Amidohydrolase 15 278 4.1E-36 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS05925 5e69a7c5360db1d712157c77f46d39ac 278 Gene3D G3DSA:3.20.20.140 1 278 9.3E-38 T 28-03-2018 hmeg3_RS18955 3cc064d9af16ab869d1d782213e6ee05 227 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 25 226 2.5E-51 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18955 3cc064d9af16ab869d1d782213e6ee05 227 Gene3D G3DSA:3.90.850.10 8 227 1.6E-75 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18955 3cc064d9af16ab869d1d782213e6ee05 227 SUPERFAMILY SSF56529 20 227 1.31E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS21245 6be71f01697926778bb7e51733188a28 282 SUPERFAMILY SSF51735 18 263 3.81E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21245 6be71f01697926778bb7e51733188a28 282 Gene3D G3DSA:3.40.50.720 60 276 1.2E-18 T 28-03-2018 hmeg3_RS21245 6be71f01697926778bb7e51733188a28 282 Gene3D G3DSA:3.40.50.720 14 59 0.0084 T 28-03-2018 hmeg3_RS21245 6be71f01697926778bb7e51733188a28 282 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 214 1.6E-16 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS03375 0b5a326ec122c7183db02c55bbe7c1d4 212 PIRSF PIRSF004553 19 210 3.8E-41 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 hmeg3_RS03375 0b5a326ec122c7183db02c55bbe7c1d4 212 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 142 148 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS03375 0b5a326ec122c7183db02c55bbe7c1d4 212 Pfam PF03602 Conserved hypothetical protein 95 20 206 7.6E-47 T 28-03-2018 hmeg3_RS03375 0b5a326ec122c7183db02c55bbe7c1d4 212 Gene3D G3DSA:3.40.50.150 7 211 5.0E-34 T 28-03-2018 hmeg3_RS03375 0b5a326ec122c7183db02c55bbe7c1d4 212 SUPERFAMILY SSF53335 19 207 1.67E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS03375 0b5a326ec122c7183db02c55bbe7c1d4 212 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 15 208 1.4E-43 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SMART SM01068 2113 2178 8.3E-29 T 28-03-2018 IPR009342 Putative carbohydrate binding domain hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SMART SM01068 1603 1664 2.0E-24 T 28-03-2018 IPR009342 Putative carbohydrate binding domain hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Gene3D G3DSA:3.90.550.10 489 762 9.0E-7 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2407 2833 2.5E-117 T 28-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SUPERFAMILY SSF53448 532 563 7.5E-6 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SUPERFAMILY SSF53448 680 791 7.5E-6 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SUPERFAMILY SSF53448 594 648 7.5E-6 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Pfam PF06165 Glycosyltransferase family 36 2136 2375 2.1E-80 T 28-03-2018 IPR010383 Glycosyl hydrolase 94 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Pfam PF06165 Glycosyltransferase family 36 1626 1875 5.1E-86 T 28-03-2018 IPR010383 Glycosyl hydrolase 94 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Gene3D G3DSA:2.70.98.40 1609 1889 3.7E-95 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Gene3D G3DSA:2.70.98.40 2114 2389 2.9E-92 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SUPERFAMILY SSF48208 2390 2875 7.48E-96 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Gene3D G3DSA:2.60.420.10 2824 2917 1.9E-17 T 28-03-2018 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Pfam PF10091 Putative glucoamylase 1370 1556 2.1E-12 T 28-03-2018 IPR019282 Domain of unknown function DUF2329 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SUPERFAMILY SSF74650 2113 2377 2.64E-87 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 Gene3D G3DSA:1.50.10.10 2422 2797 1.6E-82 T 28-03-2018 hmeg3_RS15680 84f1d99fbcf07e3f062272fb9e9c4c93 2919 SUPERFAMILY SSF74650 1610 1877 5.34E-83 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 71 114 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 87 102 1.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 102 118 1.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 SUPERFAMILY SSF46689 74 121 7.18E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 SMART SM00342 36 118 2.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 Gene3D G3DSA:1.10.10.60 10 70 6.6E-4 T 28-03-2018 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 Pfam PF12833 Helix-turn-helix domain 44 119 1.7E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS23460 006475c800feac3e584e47efa4f6cdf2 133 Gene3D G3DSA:1.10.10.60 71 124 5.0E-15 T 28-03-2018 hmeg3_RS13555 f04a85796c78b515e486093678c28ebb 201 Gene3D G3DSA:3.40.50.150 6 200 4.7E-20 T 28-03-2018 hmeg3_RS13555 f04a85796c78b515e486093678c28ebb 201 Pfam PF13649 Methyltransferase domain 45 140 2.8E-11 T 28-03-2018 hmeg3_RS13555 f04a85796c78b515e486093678c28ebb 201 SUPERFAMILY SSF53335 14 194 7.08E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 Pfam PF00012 Hsp70 protein 4 604 1.6E-259 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 Gene3D G3DSA:3.30.420.40 198 367 4.7E-47 T 28-03-2018 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 Gene3D G3DSA:1.20.1270.10 533 618 3.5E-23 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 199 209 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 470 486 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 366 386 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 335 351 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 389 408 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.6E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 SUPERFAMILY SSF53067 4 184 2.04E-65 T 28-03-2018 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.2E-285 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 SUPERFAMILY SSF100920 386 540 4.05E-61 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 Gene3D G3DSA:3.30.420.40 1 197 1.7E-81 T 28-03-2018 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 SUPERFAMILY SSF100934 508 604 3.14E-22 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 SUPERFAMILY SSF53067 188 383 6.79E-65 T 28-03-2018 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 646 36.642 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 hmeg3_RS20385 651e23af341e6c538cab01e1ec9daf4c 647 Gene3D G3DSA:2.60.34.10 391 532 2.3E-66 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 hmeg3_RS08120 4076114efa898e480d7cccb1defe691b 201 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 19 173 29.326 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 hmeg3_RS08120 4076114efa898e480d7cccb1defe691b 201 Pfam PF03975 CheD chemotactic sensory transduction 66 169 3.3E-34 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 hmeg3_RS08120 4076114efa898e480d7cccb1defe691b 201 SUPERFAMILY SSF64438 25 176 1.65E-52 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 371 384 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 386 9.6E-130 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 325 332 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 313 334 9.7E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 50 71 9.7E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 77 97 9.7E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 174 192 9.7E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 16 386 4.9E-116 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 SUPERFAMILY SSF56542 229 427 1.16E-105 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 SUPERFAMILY SSF56542 7 119 1.16E-105 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 Gene3D G3DSA:3.90.770.10 221 390 5.6E-38 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 SUPERFAMILY SSF55035 111 219 4.97E-33 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 Gene3D G3DSA:3.90.770.10 4 117 9.8E-26 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 176 190 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS13460 0b904025731319a6f2062a2a18602cff 428 Gene3D G3DSA:3.30.70.420 118 219 2.4E-28 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 SMART SM00387 474 586 1.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 SUPERFAMILY SSF55874 437 586 1.24E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Gene3D G3DSA:3.30.565.10 437 589 7.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Pfam PF13426 PAS domain 239 338 2.2E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 585 2.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Pfam PF05227 CHASE3 domain 45 172 6.5E-14 T 28-03-2018 IPR007891 CHASE3 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Gene3D G3DSA:1.10.287.130 357 431 4.8E-14 T 28-03-2018 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Pfam PF00512 His Kinase A (phospho-acceptor) domain 369 435 5.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 1.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 1.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 527 1.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 SUPERFAMILY SSF55785 223 321 2.09E-12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 Gene3D G3DSA:3.30.450.20 198 356 1.5E-15 T 28-03-2018 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 SUPERFAMILY SSF47384 353 436 5.89E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 226 346 3.2E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS10515 29e70babd513f41018f71170ac0a971c 590 SMART SM00388 367 435 2.9E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15305 e1d01459e0af597bc805107ddb4d93e4 244 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 32 227 1.7E-83 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 hmeg3_RS15305 e1d01459e0af597bc805107ddb4d93e4 244 Gene3D G3DSA:3.40.50.620 1 241 1.4E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS15305 e1d01459e0af597bc805107ddb4d93e4 244 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 203 2.1E-41 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 hmeg3_RS15305 e1d01459e0af597bc805107ddb4d93e4 244 PIRSF PIRSF000857 2 234 6.6E-84 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 hmeg3_RS15305 e1d01459e0af597bc805107ddb4d93e4 244 SUPERFAMILY SSF52402 5 191 1.44E-46 T 28-03-2018 hmeg3_RS15305 e1d01459e0af597bc805107ddb4d93e4 244 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 27 228 6.6E-50 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 hmeg3_RS23625 19f1a4c0f31b8726fbf380e20f21f524 521 SMART SM00457 123 313 4.7E-10 T 28-03-2018 IPR020864 Membrane attack complex component/perforin (MACPF) domain hmeg3_RS23625 19f1a4c0f31b8726fbf380e20f21f524 521 Pfam PF01823 MAC/Perforin domain 106 311 1.4E-27 T 28-03-2018 IPR020864 Membrane attack complex component/perforin (MACPF) domain hmeg3_RS05595 d9dd48d1c3940052c274896826004490 129 Pfam PF02033 Ribosome-binding factor A 11 115 6.0E-30 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 hmeg3_RS05595 d9dd48d1c3940052c274896826004490 129 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 11 119 7.2E-30 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 hmeg3_RS05595 d9dd48d1c3940052c274896826004490 129 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 14 102 1.0E-27 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 hmeg3_RS05595 d9dd48d1c3940052c274896826004490 129 Gene3D G3DSA:3.30.300.20 10 122 6.3E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS05595 d9dd48d1c3940052c274896826004490 129 SUPERFAMILY SSF89919 11 118 1.02E-31 T 28-03-2018 IPR023799 Ribosome-binding factor A domain hmeg3_RS05595 d9dd48d1c3940052c274896826004490 129 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 7 122 21.168 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 SUPERFAMILY SSF63867 339 411 5.49E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Pfam PF00994 Probable molybdopterin binding domain 185 327 6.4E-28 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Pfam PF03454 MoeA C-terminal region (domain IV) 344 409 9.7E-10 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Gene3D G3DSA:2.40.340.10 339 411 1.5E-12 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 258 291 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 SUPERFAMILY SSF53218 182 334 3.93E-42 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 181 325 9.1E-27 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Gene3D G3DSA:3.90.105.10 27 61 6.8E-9 T 28-03-2018 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 SUPERFAMILY SSF63882 7 180 1.31E-49 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 SMART SM00852 185 329 8.8E-45 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Gene3D G3DSA:3.40.980.10 155 336 1.0E-51 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Gene3D G3DSA:2.170.190.11 62 146 2.8E-27 T 28-03-2018 hmeg3_RS13450 63564dc4ac70caaab605587f568d3b1a 414 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 172 7.2E-42 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS08910 9307d4d61548f3e169fe4a69d86183d8 294 SUPERFAMILY SSF117892 54 191 2.75E-23 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS08910 9307d4d61548f3e169fe4a69d86183d8 294 TIGRFAM TIGR01932 hflC: HflC protein 153 284 5.0E-47 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 hmeg3_RS08910 9307d4d61548f3e169fe4a69d86183d8 294 SMART SM00244 20 185 2.1E-25 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS08910 9307d4d61548f3e169fe4a69d86183d8 294 Pfam PF01145 SPFH domain / Band 7 family 24 198 3.0E-27 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS08910 9307d4d61548f3e169fe4a69d86183d8 294 PIRSF PIRSF005651 1 294 1.3E-94 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SUPERFAMILY SSF47781 482 568 3.56E-26 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Gene3D G3DSA:1.10.150.310 511 642 1.3E-41 T 28-03-2018 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Pfam PF09371 Tex-like protein N-terminal domain 10 201 4.5E-67 T 28-03-2018 IPR018974 Tex-like protein, N-terminal hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Gene3D G3DSA:1.10.3500.10 103 364 4.8E-76 T 28-03-2018 IPR023323 Tex-like domain hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SUPERFAMILY SSF47781 572 644 8.23E-21 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Pfam PF16921 Tex protein YqgF-like domain 338 463 5.9E-52 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Gene3D G3DSA:1.10.3500.10 365 510 1.1E-39 T 28-03-2018 IPR023323 Tex-like domain hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SMART SM00316 661 732 8.7E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SMART SM00732 337 436 1.1E-35 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Pfam PF00575 S1 RNA binding domain 662 732 3.1E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Pfam PF12836 Helix-hairpin-helix motif 503 567 2.6E-25 T 28-03-2018 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Gene3D G3DSA:1.10.10.650 3 102 1.6E-31 T 28-03-2018 IPR023319 Tex-like protein, HTH domain hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 Gene3D G3DSA:2.40.50.140 664 769 6.4E-26 T 28-03-2018 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SUPERFAMILY SSF50249 649 738 7.31E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SUPERFAMILY SSF53098 333 481 1.29E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS03155 dc4d1969572de6a4dc628d7ca9f79824 783 SUPERFAMILY SSF158832 2 332 5.36E-112 T 28-03-2018 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 SUPERFAMILY SSF55031 183 296 1.7E-32 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 Pfam PF01546 Peptidase family M20/M25/M40 73 391 4.7E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 SUPERFAMILY SSF53187 298 394 1.89E-90 T 28-03-2018 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 SUPERFAMILY SSF53187 4 197 1.89E-90 T 28-03-2018 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 Pfam PF07687 Peptidase dimerisation domain 185 281 8.4E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 PIRSF PIRSF005962 3 397 2.8E-132 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 382 4.4E-116 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 Gene3D G3DSA:3.40.630.10 231 397 7.2E-22 T 28-03-2018 hmeg3_RS07540 58e9b760bda4264e16090deec19846e2 397 Gene3D G3DSA:3.40.630.10 3 225 3.9E-53 T 28-03-2018 hmeg3_RS12685 53ac3c64cf3b8537fad04af6334c7376 103 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 97 8.0E-28 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit hmeg3_RS12685 53ac3c64cf3b8537fad04af6334c7376 103 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 19 98 7.5E-26 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein hmeg3_RS12685 53ac3c64cf3b8537fad04af6334c7376 103 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 98 3.2E-35 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit hmeg3_RS12685 53ac3c64cf3b8537fad04af6334c7376 103 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 103 49.517 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 Gene3D G3DSA:1.10.287.1060 242 327 0.028 T 28-03-2018 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 SMART SM00283 266 513 4.3E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.7E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.7E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.7E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.7E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 Gene3D G3DSA:1.10.287.950 328 517 3.7E-50 T 28-03-2018 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 SUPERFAMILY SSF58104 233 519 1.16E-76 T 28-03-2018 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 SMART SM00304 213 265 3.5E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 185 3.7E-20 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 Gene3D G3DSA:1.20.120.30 24 187 2.1E-17 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS19760 c6426f98c1dd0575d875da65e06e342c 582 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 2.6E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS18765 29f84fdcdfa8498e356e7df5d31c77b3 296 SUPERFAMILY SSF103481 210 288 2.48E-5 T 28-03-2018 hmeg3_RS18765 29f84fdcdfa8498e356e7df5d31c77b3 296 SUPERFAMILY SSF103481 72 148 7.06E-5 T 28-03-2018 hmeg3_RS18765 29f84fdcdfa8498e356e7df5d31c77b3 296 TIGRFAM TIGR00688 rarD: protein RarD 8 262 1.5E-49 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 hmeg3_RS19180 3192ee588eab7f3fcade0c191a220dc5 288 Gene3D G3DSA:1.10.3470.10 1 280 1.9E-44 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS19180 3192ee588eab7f3fcade0c191a220dc5 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 275 3.2E-42 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS07645 b45d801f3ad73aa22d167325586f053c 397 SUPERFAMILY SSF53383 11 393 4.4E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS07645 b45d801f3ad73aa22d167325586f053c 397 Gene3D G3DSA:3.90.1150.10 272 396 1.5E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS07645 b45d801f3ad73aa22d167325586f053c 397 Pfam PF00155 Aminotransferase class I and II 53 389 2.6E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS07645 b45d801f3ad73aa22d167325586f053c 397 Gene3D G3DSA:3.40.640.10 62 271 7.0E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS07035 5bce43bcbf2d94b4c140d013b2fcc615 318 SUPERFAMILY SSF53822 10 317 4.38E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS07035 5bce43bcbf2d94b4c140d013b2fcc615 318 Gene3D G3DSA:3.40.50.2300 157 309 1.5E-38 T 28-03-2018 hmeg3_RS07035 5bce43bcbf2d94b4c140d013b2fcc615 318 Pfam PF13407 Periplasmic binding protein domain 34 296 3.3E-51 T 28-03-2018 IPR025997 Periplasmic binding protein hmeg3_RS07035 5bce43bcbf2d94b4c140d013b2fcc615 318 Gene3D G3DSA:3.40.50.2300 30 156 8.6E-21 T 28-03-2018 hmeg3_RS19665 26b988396cc0ccb274087a5a605d655a 324 Pfam PF00591 Glycosyl transferase family, a/b domain 105 308 7.2E-10 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS19665 26b988396cc0ccb274087a5a605d655a 324 Gene3D G3DSA:1.20.970.10 9 94 5.3E-15 T 28-03-2018 hmeg3_RS19665 26b988396cc0ccb274087a5a605d655a 324 SUPERFAMILY SSF47648 18 83 4.32E-15 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS19665 26b988396cc0ccb274087a5a605d655a 324 Gene3D G3DSA:3.40.1030.10 95 324 4.0E-44 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS19665 26b988396cc0ccb274087a5a605d655a 324 SUPERFAMILY SSF52418 87 318 9.42E-45 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS19665 26b988396cc0ccb274087a5a605d655a 324 Pfam PF02885 Glycosyl transferase family, helical bundle domain 19 76 1.6E-10 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS03210 3422b19114a074e64a739e19ea4c685b 239 PIRSF PIRSF006293 8 239 1.3E-69 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 hmeg3_RS03210 3422b19114a074e64a739e19ea4c685b 239 Pfam PF06508 Queuosine biosynthesis protein QueC 11 235 2.3E-72 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 hmeg3_RS03210 3422b19114a074e64a739e19ea4c685b 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 12 228 1.0E-60 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 hmeg3_RS03210 3422b19114a074e64a739e19ea4c685b 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 10 236 49.005 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 hmeg3_RS03210 3422b19114a074e64a739e19ea4c685b 239 SUPERFAMILY SSF52402 11 235 1.1E-53 T 28-03-2018 hmeg3_RS03210 3422b19114a074e64a739e19ea4c685b 239 Gene3D G3DSA:3.40.50.620 9 239 4.8E-46 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 Gene3D G3DSA:1.10.10.10 8 77 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 SUPERFAMILY SSF46785 14 105 6.56E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 SUPERFAMILY SSF48008 88 227 2.38E-14 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 SMART SM00345 24 82 7.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 SMART SM00895 92 221 3.6E-9 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 Gene3D G3DSA:1.20.120.530 78 229 2.7E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 6.7E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17650 77562447487cc66da83c860b297ae54c 235 Pfam PF07729 FCD domain 92 213 7.0E-14 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS23480 273f5400e33428c68c267a0a6abb5a06 222 Pfam PF01339 CheB methylesterase 17 192 2.2E-57 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS23480 273f5400e33428c68c267a0a6abb5a06 222 SUPERFAMILY SSF52738 14 198 3.27E-57 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS23480 273f5400e33428c68c267a0a6abb5a06 222 Gene3D G3DSA:3.40.50.180 8 205 6.2E-67 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 SUPERFAMILY SSF53850 94 302 5.21E-32 T 28-03-2018 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 Pfam PF03466 LysR substrate binding domain 91 296 9.6E-38 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.4E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 Gene3D G3DSA:1.10.10.10 1 86 4.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 Gene3D G3DSA:3.40.190.10 182 274 2.1E-22 T 28-03-2018 hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 SUPERFAMILY SSF46785 4 88 2.45E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17750 46229965b953fa43225e4e0a0339c837 313 Gene3D G3DSA:3.40.190.10 91 181 4.9E-18 T 28-03-2018 hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 Pfam PF00176 SNF2 family N-terminal domain 379 647 9.0E-57 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 SUPERFAMILY SSF52540 577 829 3.34E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 SUPERFAMILY SSF52540 338 575 6.55E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 SMART SM00487 360 544 2.0E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 Gene3D G3DSA:3.40.50.300 652 814 1.0E-35 T 28-03-2018 hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 SMART SM00490 694 776 4.3E-20 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 Gene3D G3DSA:3.40.50.10810 340 584 1.5E-50 T 28-03-2018 hmeg3_RS18795 2d6434e91594476533cd9465f67bdc27 840 Pfam PF00271 Helicase conserved C-terminal domain 665 776 3.9E-17 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 Pfam PF01938 TRAM domain 378 443 5.2E-15 T 28-03-2018 IPR002792 TRAM domain hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 SMART SM00729 147 367 2.2E-52 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 443 5.5E-178 T 28-03-2018 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 Pfam PF04055 Radical SAM superfamily 151 325 1.6E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 SUPERFAMILY SSF102114 129 371 7.85E-59 T 28-03-2018 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 444 72.571 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 4.4E-30 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 440 4.3E-144 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 hmeg3_RS19805 8070a5bfd84cadf4c8f341da68818c13 446 Gene3D G3DSA:3.80.30.20 144 381 1.9E-53 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 Gene3D G3DSA:3.40.140.10 1 121 1.8E-30 T 28-03-2018 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 Pfam PF01872 RibD C-terminal domain 144 347 2.3E-49 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 85 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 Gene3D G3DSA:3.40.430.10 122 354 6.8E-69 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 96 6.5E-18 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 SUPERFAMILY SSF53927 1 141 1.76E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 347 1.1E-111 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 143 351 3.7E-56 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 SUPERFAMILY SSF53597 142 352 7.85E-59 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 hmeg3_RS05150 8a6adb91f16ac0525cf1b1af3e6998c2 354 PIRSF PIRSF006769 1 354 1.7E-117 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Gene3D G3DSA:1.10.730.10 629 851 4.1E-53 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 32 877 5.4E-264 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Gene3D G3DSA:3.40.50.620 418 628 9.9E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Pfam PF06827 Zinc finger found in FPG and IleRS 925 952 1.7E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 SUPERFAMILY SSF50677 218 429 2.3E-48 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 19 955 20.264 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 SUPERFAMILY SSF52374 429 681 1.34E-127 T 28-03-2018 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 SUPERFAMILY SSF52374 25 216 1.34E-127 T 28-03-2018 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Gene3D G3DSA:3.40.50.620 64 227 7.3E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Pfam PF08264 Anticodon-binding domain of tRNA 718 877 3.1E-23 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 44 674 3.5E-190 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 68 79 3.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 427 442 3.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 558 571 3.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 594 603 3.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 253 276 3.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Gene3D G3DSA:3.30.2320.20 852 930 9.7E-19 T 28-03-2018 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 Gene3D G3DSA:3.90.740.10 228 417 5.0E-53 T 28-03-2018 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 75 86 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS06665 35e56db49917d24a9717ea63b0236120 964 SUPERFAMILY SSF47323 685 954 1.48E-66 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS16430 9657fe0f933eb2a6fa398bd342b676fe 250 SUPERFAMILY SSF53955 73 212 1.55E-42 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS16430 9657fe0f933eb2a6fa398bd342b676fe 250 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 99 127 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 hmeg3_RS16430 9657fe0f933eb2a6fa398bd342b676fe 250 Pfam PF01464 Transglycosylase SLT domain 84 189 2.9E-30 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 hmeg3_RS16430 9657fe0f933eb2a6fa398bd342b676fe 250 Gene3D G3DSA:1.10.530.10 57 214 3.1E-43 T 28-03-2018 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 SUPERFAMILY SSF118215 10 402 1.15E-119 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 2.6E-32 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 2.6E-32 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 2.6E-32 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 2.6E-32 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 2.6E-32 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 PRINTS PR00173 Glutamate-aspartate symporter signature 45 65 2.6E-32 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 37 52 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 3 429 38.239 T 28-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 Gene3D G3DSA:1.10.3860.10 4 409 1.1E-113 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS10300 e2e3aaa449029cf4ab8a81b2ecd33afb 439 Pfam PF00375 Sodium:dicarboxylate symporter family 10 402 6.0E-109 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 Gene3D G3DSA:3.40.50.180 193 381 5.7E-71 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 Gene3D G3DSA:3.40.50.2300 1 142 2.2E-28 T 28-03-2018 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 PIRSF PIRSF000876 1 381 2.3E-125 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 SUPERFAMILY SSF52738 196 380 6.28E-67 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 382 37.956 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 SMART SM00448 3 126 1.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 Pfam PF01339 CheB methylesterase 199 376 2.6E-57 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 Pfam PF00072 Response regulator receiver domain 5 108 1.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20310 7ca9b583bf0ded94d685fcf41541af43 382 SUPERFAMILY SSF52172 2 130 3.27E-27 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 Gene3D G3DSA:3.30.300.30 350 465 1.9E-16 T 28-03-2018 hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 Gene3D G3DSA:3.40.50.980 142 296 3.0E-20 T 28-03-2018 hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 SUPERFAMILY SSF56801 15 462 1.57E-50 T 28-03-2018 hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 Gene3D G3DSA:3.40.50.980 6 92 0.19 T 28-03-2018 hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 Gene3D G3DSA:3.40.50.980 93 141 0.13 T 28-03-2018 hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 SUPERFAMILY SSF54637 481 563 1.08E-12 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 Pfam PF00501 AMP-binding enzyme 113 309 2.0E-16 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS16200 ead5248de60e854593dd7592d0a68921 586 Gene3D G3DSA:3.10.129.10 472 585 1.9E-18 T 28-03-2018 hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 Gene3D G3DSA:3.40.50.720 1 261 3.7E-56 T 28-03-2018 hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 SUPERFAMILY SSF51735 6 262 1.39E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 261 3.1E-39 T 28-03-2018 hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 5.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 5.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS12940 3d2c44df210aac9e778e55f90e627274 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 5.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 SUPERFAMILY SSF48008 107 238 1.7E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 Pfam PF07729 FCD domain 112 233 2.6E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 SUPERFAMILY SSF46785 41 119 3.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 SMART SM00895 111 234 1.2E-18 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 Gene3D G3DSA:1.10.10.10 22 97 8.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 43 101 2.3E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 SMART SM00345 43 101 3.5E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS06085 846d6858a368ca74fe8155e036a24fb2 258 Gene3D G3DSA:1.20.120.530 98 251 5.8E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS22915 991e887bccedcfb203bef7903c948c91 165 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22915 991e887bccedcfb203bef7903c948c91 165 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 25.743 T 28-03-2018 IPR022973 Ribosomal protein L10 hmeg3_RS22915 991e887bccedcfb203bef7903c948c91 165 Pfam PF00466 Ribosomal protein L10 6 100 9.9E-22 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 hmeg3_RS22915 991e887bccedcfb203bef7903c948c91 165 SUPERFAMILY SSF160369 4 159 1.44E-46 T 28-03-2018 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 Gene3D G3DSA:3.40.190.10 80 186 9.1E-16 T 28-03-2018 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 Gene3D G3DSA:3.40.190.10 187 267 1.2E-12 T 28-03-2018 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 Gene3D G3DSA:1.10.10.10 1 79 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 SUPERFAMILY SSF46785 1 111 2.41E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 Pfam PF03466 LysR substrate binding domain 89 279 1.5E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23510 088260a8e20d1da2729714d5daae30d2 320 SUPERFAMILY SSF53850 90 280 5.43E-32 T 28-03-2018 hmeg3_RS10905 1fba3c9056362ae1dc6438aa937b1375 402 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 289 295 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS10905 1fba3c9056362ae1dc6438aa937b1375 402 Gene3D G3DSA:3.40.50.150 45 400 2.7E-25 T 28-03-2018 hmeg3_RS10905 1fba3c9056362ae1dc6438aa937b1375 402 Pfam PF05175 Methyltransferase small domain 219 340 2.3E-11 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 hmeg3_RS10905 1fba3c9056362ae1dc6438aa937b1375 402 SUPERFAMILY SSF53335 187 339 2.37E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 SUPERFAMILY SSF55874 283 446 2.1E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 288 4.2E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 SMART SM00387 331 446 1.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 444 2.6E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 SMART SM00388 233 292 3.3E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 Gene3D G3DSA:3.30.565.10 298 455 4.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 SMART SM00304 180 232 1.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 Pfam PF00672 HAMP domain 182 228 9.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 46 151 3.3E-38 T 28-03-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 5.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 400 5.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 5.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 5.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 SUPERFAMILY SSF158472 182 229 6.41E-6 T 28-03-2018 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 SUPERFAMILY SSF47384 219 288 1.1E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS09815 62d40c1f87c4179c187247a18b6a9f30 456 Gene3D G3DSA:1.10.287.130 223 288 4.1E-9 T 28-03-2018 hmeg3_RS02895 36d103aa56c80189260958f34cff0be7 202 SUPERFAMILY SSF100950 28 201 7.12E-39 T 28-03-2018 hmeg3_RS02895 36d103aa56c80189260958f34cff0be7 202 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 29 200 1.2E-23 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase hmeg3_RS02895 36d103aa56c80189260958f34cff0be7 202 Gene3D G3DSA:3.40.50.10420 17 202 2.0E-44 T 28-03-2018 hmeg3_RS02895 36d103aa56c80189260958f34cff0be7 202 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 29 200 1.2E-38 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase hmeg3_RS02895 36d103aa56c80189260958f34cff0be7 202 PIRSF PIRSF006806 24 202 1.2E-34 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 PIRSF PIRSF005902 1 259 3.0E-80 T 28-03-2018 IPR001130 TatD family GO:0016788 hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 Gene3D G3DSA:3.20.20.140 1 259 5.9E-85 T 28-03-2018 hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 123 133 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 256 5.3E-84 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 Pfam PF01026 TatD related DNase 3 256 3.9E-78 T 28-03-2018 IPR001130 TatD family GO:0016788 hmeg3_RS10365 d63cdc784054af43e6ffd3cb5fc3c967 259 SUPERFAMILY SSF51556 1 257 2.04E-87 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 3.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 289 302 3.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 3.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 SUPERFAMILY SSF53822 30 391 6.77E-75 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 Gene3D G3DSA:3.40.50.2300 28 209 4.4E-36 T 28-03-2018 hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 Gene3D G3DSA:3.40.50.2300 210 377 8.1E-19 T 28-03-2018 hmeg3_RS06000 8dceb08e637d5c21bf43924f6f72bcd5 395 Pfam PF13458 Periplasmic binding protein 32 361 3.9E-55 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 PIRSF PIRSF001365 4 301 1.0E-51 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.0E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 1.0E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 1.0E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 Pfam PF00701 Dihydrodipicolinate synthetase family 8 296 2.2E-43 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 SUPERFAMILY SSF51569 8 299 8.37E-72 T 28-03-2018 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 SMART SM01130 7 298 5.6E-73 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS08025 70463a4a4b85d7c2da6ad36c30eab583 306 Gene3D G3DSA:3.20.20.70 1 299 1.1E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS12550 03c7dd49e05d59d5cf0dc4243e988efd 315 PIRSF PIRSF037442 3 285 6.1E-91 T 28-03-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 hmeg3_RS12550 03c7dd49e05d59d5cf0dc4243e988efd 315 Gene3D G3DSA:3.40.50.1820 3 284 7.7E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12550 03c7dd49e05d59d5cf0dc4243e988efd 315 SUPERFAMILY SSF53474 206 284 9.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12550 03c7dd49e05d59d5cf0dc4243e988efd 315 SUPERFAMILY SSF53474 5 143 9.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12550 03c7dd49e05d59d5cf0dc4243e988efd 315 Pfam PF12146 Serine aminopeptidase, S33 44 149 1.7E-9 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 Pfam PF00005 ABC transporter 34 177 2.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 Gene3D G3DSA:2.40.50.140 288 351 2.8E-4 T 28-03-2018 hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 SMART SM00382 43 227 1.6E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 SUPERFAMILY SSF50331 253 358 2.25E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 Pfam PF08402 TOBE domain 287 355 2.1E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 Gene3D G3DSA:3.40.50.300 13 262 1.3E-72 T 28-03-2018 hmeg3_RS20455 2663a55fbf85fce528c5b8d0d1abec4f 369 SUPERFAMILY SSF52540 18 256 1.45E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 333 346 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 89 360 58.008 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 SMART SM00382 159 338 2.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 Gene3D G3DSA:1.20.120.140 272 360 8.4E-25 T 28-03-2018 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 SUPERFAMILY SSF52540 158 359 6.19E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 SUPERFAMILY SSF47364 65 139 5.76E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 Gene3D G3DSA:1.20.120.140 64 159 4.4E-17 T 28-03-2018 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 SMART SM00962 160 360 2.4E-106 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 Gene3D G3DSA:3.40.50.300 160 271 3.4E-11 T 28-03-2018 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 Pfam PF00448 SRP54-type protein, GTPase domain 161 359 7.2E-72 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 Pfam PF02881 SRP54-type protein, helical bundle domain 80 140 7.7E-10 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 91 359 5.3E-101 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 hmeg3_RS03355 7d021380fc192af6e0a00f262b74f564 360 SMART SM00963 70 146 3.1E-16 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Gene3D G3DSA:2.160.10.10 22 174 1.2E-19 T 28-03-2018 hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 264 293 0.017 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 8 330 35.486 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 163 1.7E-4 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 226 261 6.6E-6 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 22 91 6.2E-21 T 28-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 7 333 1.6E-106 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 Gene3D G3DSA:2.160.10.10 175 357 2.8E-26 T 28-03-2018 hmeg3_RS09985 0670d3541340795fb262452a6f4785cb 358 SUPERFAMILY SSF51161 31 320 7.48E-75 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS20800 391192ab68556c0efef7955951271ba7 207 Gene3D G3DSA:3.40.30.10 1 98 2.7E-28 T 28-03-2018 hmeg3_RS20800 391192ab68556c0efef7955951271ba7 207 Pfam PF00043 Glutathione S-transferase, C-terminal domain 119 196 3.6E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS20800 391192ab68556c0efef7955951271ba7 207 Pfam PF13417 Glutathione S-transferase, N-terminal domain 7 79 3.7E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS20800 391192ab68556c0efef7955951271ba7 207 SUPERFAMILY SSF47616 79 201 2.37E-31 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS20800 391192ab68556c0efef7955951271ba7 207 Gene3D G3DSA:1.20.1050.10 99 201 4.7E-25 T 28-03-2018 hmeg3_RS20800 391192ab68556c0efef7955951271ba7 207 SUPERFAMILY SSF52833 1 85 2.01E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS20420 008eb537489d0116f0ef20ba41c90a63 141 Pfam PF01475 Ferric uptake regulator family 11 130 6.3E-45 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 hmeg3_RS20420 008eb537489d0116f0ef20ba41c90a63 141 Gene3D G3DSA:1.10.10.10 4 90 5.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20420 008eb537489d0116f0ef20ba41c90a63 141 SUPERFAMILY SSF46785 7 135 8.25E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08925 57b445a530262b3224735b823e483faa 178 Pfam PF00156 Phosphoribosyl transferase domain 13 158 1.2E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 hmeg3_RS08925 57b445a530262b3224735b823e483faa 178 SUPERFAMILY SSF53271 5 175 1.28E-32 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS08925 57b445a530262b3224735b823e483faa 178 Gene3D G3DSA:3.40.50.2020 3 158 1.6E-21 T 28-03-2018 hmeg3_RS22040 35d9e4b5e14b5d76fd13ac9a3cbc87db 593 Gene3D G3DSA:3.40.710.10 245 590 6.5E-85 T 28-03-2018 hmeg3_RS22040 35d9e4b5e14b5d76fd13ac9a3cbc87db 593 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 563 2.7E-72 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 hmeg3_RS22040 35d9e4b5e14b5d76fd13ac9a3cbc87db 593 SUPERFAMILY SSF56601 244 573 9.68E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS22040 35d9e4b5e14b5d76fd13ac9a3cbc87db 593 Pfam PF03717 Penicillin-binding Protein dimerisation domain 81 229 3.9E-21 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 hmeg3_RS22040 35d9e4b5e14b5d76fd13ac9a3cbc87db 593 Gene3D G3DSA:3.90.1310.10 50 244 1.3E-46 T 28-03-2018 hmeg3_RS22040 35d9e4b5e14b5d76fd13ac9a3cbc87db 593 SUPERFAMILY SSF56519 77 243 1.27E-44 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 PRINTS PR00127 Clp protease catalytic subunit P signature 67 87 9.2E-51 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 PRINTS PR00127 Clp protease catalytic subunit P signature 27 42 9.2E-51 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 PRINTS PR00127 Clp protease catalytic subunit P signature 98 115 9.2E-51 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 PRINTS PR00127 Clp protease catalytic subunit P signature 119 138 9.2E-51 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 9.2E-51 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 Pfam PF00574 Clp protease 21 199 1.0E-82 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 120 133 - T 28-03-2018 IPR033135 ClpP, histidine active site hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 10 198 2.8E-96 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 Gene3D G3DSA:3.90.226.10 10 202 6.2E-44 T 28-03-2018 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 11 201 43.027 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS12100 ecbb772e4e49c3beffc70b60466eefc9 205 SUPERFAMILY SSF52096 19 202 3.73E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 453 1.2E-117 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 SMART SM00851 14 129 5.6E-64 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 Gene3D G3DSA:3.40.50.1380 1 192 9.8E-77 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 523 44.486 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 SUPERFAMILY SSF53927 214 523 5.01E-124 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 Gene3D G3DSA:3.40.140.20 230 369 3.1E-50 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 Pfam PF02142 MGS-like domain 14 128 4.7E-30 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 SMART SM00798 134 455 2.4E-202 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 523 1.7E-222 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 PIRSF PIRSF000414 1 523 3.8E-213 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 Gene3D G3DSA:3.40.140.20 370 513 1.4E-48 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS21645 9b7847194e64daa71c8cf3c23a512ce4 523 SUPERFAMILY SSF52335 2 192 2.22E-70 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS21515 6421679b1328d5a565f02a4f72840eb0 300 Gene3D G3DSA:3.40.1190.20 5 300 5.1E-50 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS21515 6421679b1328d5a565f02a4f72840eb0 300 SUPERFAMILY SSF53613 5 297 1.29E-58 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS21515 6421679b1328d5a565f02a4f72840eb0 300 Pfam PF00294 pfkB family carbohydrate kinase 8 289 4.6E-37 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 395 401 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SUPERFAMILY SSF56784 551 705 8.65E-39 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Gene3D G3DSA:2.70.150.10 59 294 3.0E-43 T 28-03-2018 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SUPERFAMILY SSF81665 294 387 9.02E-106 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SUPERFAMILY SSF81665 710 918 9.02E-106 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SUPERFAMILY SSF81665 53 161 9.02E-106 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Gene3D G3DSA:3.40.1110.10 350 568 3.2E-41 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Pfam PF00122 E1-E2 ATPase 189 373 2.9E-44 T 28-03-2018 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SMART SM00831 50 123 8.2E-10 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 632 750 4.0E-29 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 194 414 8.9E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SUPERFAMILY SSF81660 362 565 1.26E-43 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Pfam PF00690 Cation transporter/ATPase, N-terminus 53 118 5.2E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 41 920 0.0 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 427 440 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 789 805 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 306 322 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 737 748 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 874 895 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 323 342 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 769 782 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 719 734 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 PRINTS PR01836 Magnesium-transporting ATPase signature 824 845 2.6E-84 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 SUPERFAMILY SSF81653 190 292 7.59E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Pfam PF00689 Cation transporting ATPase, C-terminus 744 910 1.1E-16 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Pfam PF00702 haloacid dehalogenase-like hydrolase 389 675 1.1E-20 T 28-03-2018 hmeg3_RS07140 2aac5cd9f298277a49c96cf2ae7b989f 920 Gene3D G3DSA:1.20.1110.10 583 915 8.7E-57 T 28-03-2018 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 Gene3D G3DSA:1.10.760.10 101 222 1.9E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 Gene3D G3DSA:1.10.760.10 223 312 9.4E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 47 93 7.7E-23 T 28-03-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 PIRSF PIRSF000006 5 306 3.8E-98 T 28-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 234 299 8.9E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 140 212 1.6E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 SUPERFAMILY SSF46626 117 226 4.51E-33 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 SUPERFAMILY SSF46626 66 89 4.51E-33 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 SUPERFAMILY SSF46626 231 308 6.73E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11605 cd4876770a02234722c5e2714d09d3ad 312 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 45 304 3.6E-87 T 28-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III hmeg3_RS10285 f62ced77c4d8466b6e333f4fbde8e9ef 100 SUPERFAMILY SSF54909 2 100 5.37E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS10285 f62ced77c4d8466b6e333f4fbde8e9ef 100 SMART SM00886 2 100 7.2E-35 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel hmeg3_RS10285 f62ced77c4d8466b6e333f4fbde8e9ef 100 Gene3D G3DSA:3.30.70.100 1 100 1.1E-28 T 28-03-2018 hmeg3_RS10285 f62ced77c4d8466b6e333f4fbde8e9ef 100 Pfam PF07876 Stress responsive A/B Barrel Domain 2 100 2.6E-24 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel hmeg3_RS00220 a4deada39c09f8dc32137eea22ab754d 475 Gene3D G3DSA:1.20.1250.20 275 475 1.1E-25 T 28-03-2018 hmeg3_RS00220 a4deada39c09f8dc32137eea22ab754d 475 Gene3D G3DSA:1.20.1250.20 27 217 6.0E-29 T 28-03-2018 hmeg3_RS00220 a4deada39c09f8dc32137eea22ab754d 475 SUPERFAMILY SSF103473 264 462 3.92E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00220 a4deada39c09f8dc32137eea22ab754d 475 SUPERFAMILY SSF103473 28 215 3.92E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00220 a4deada39c09f8dc32137eea22ab754d 475 Pfam PF07690 Major Facilitator Superfamily 36 426 8.4E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 SUPERFAMILY SSF53223 2 100 2.88E-29 T 28-03-2018 hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 9.8E-23 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 Gene3D G3DSA:3.40.50.10860 1 110 1.3E-33 T 28-03-2018 hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 SUPERFAMILY SSF51735 101 271 3.49E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 191 5.5E-12 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 272 30.501 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 Gene3D G3DSA:3.40.50.720 111 276 1.9E-32 T 28-03-2018 hmeg3_RS21710 0fc29b63f5b0ea9055408412286d4232 276 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 273 2.3E-80 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SUPERFAMILY SSF56672 526 931 2.33E-157 T 28-03-2018 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Gene3D G3DSA:3.40.50.1010 3 180 4.8E-64 T 28-03-2018 IPR029060 PIN domain-like hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SMART SM00279 169 204 1.2E-10 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SUPERFAMILY SSF53098 337 520 3.79E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Gene3D G3DSA:3.30.420.10 344 545 1.4E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Pfam PF00476 DNA polymerase family A 555 929 4.3E-155 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 ProSitePatterns PS00447 DNA polymerase family A signature. 757 776 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 7.0E-51 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SUPERFAMILY SSF47807 167 286 3.89E-30 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SMART SM00475 2 252 1.2E-102 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Gene3D G3DSA:1.10.150.20 181 256 6.1E-20 T 28-03-2018 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 251 4.6E-23 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Gene3D G3DSA:1.20.1060.10 546 659 1.7E-36 T 28-03-2018 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 TIGRFAM TIGR00593 pola: DNA polymerase I 5 931 2.0E-277 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Gene3D G3DSA:3.30.70.370 660 748 5.6E-16 T 28-03-2018 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Gene3D G3DSA:3.30.70.370 757 931 2.0E-48 T 28-03-2018 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SMART SM00474 334 520 3.6E-35 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 816 827 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 805 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 696 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 757 782 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 878 891 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 848 864 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 703 726 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 658 680 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 PRINTS PR00868 DNA-polymerase family A (pol I) signature 733 746 9.3E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SUPERFAMILY SSF88723 2 166 2.72E-53 T 28-03-2018 IPR029060 PIN domain-like hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 Pfam PF01612 3'-5' exonuclease 334 520 3.1E-35 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 hmeg3_RS21445 a33dc2e091fa755ad37d0ba7fc529433 931 SMART SM00482 689 895 5.1E-117 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 Pfam PF00072 Response regulator receiver domain 187 310 8.6E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 Gene3D G3DSA:3.40.50.2300 171 316 3.3E-21 T 28-03-2018 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 Gene3D G3DSA:2.30.30.40 109 148 1.1E-7 T 28-03-2018 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 Pfam PF01584 CheW-like domain 22 164 2.3E-31 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 SUPERFAMILY SSF52172 184 315 6.55E-20 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 SUPERFAMILY SSF50341 17 165 3.14E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 SMART SM00448 185 310 1.7E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 Gene3D G3DSA:2.40.50.180 45 108 4.3E-12 T 28-03-2018 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 SMART SM00260 17 161 1.2E-18 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS16620 c0409e29a3dfaec221bf7811435b0769 316 PIRSF PIRSF002867 1 316 5.0E-100 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 Pfam PF13533 Biotin-lipoyl like 45 91 9.7E-19 T 28-03-2018 hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 SUPERFAMILY SSF111369 42 185 3.79E-22 T 28-03-2018 hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 228 1.3E-33 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 Pfam PF13437 HlyD family secretion protein 155 235 1.6E-10 T 28-03-2018 hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 Gene3D G3DSA:2.40.50.100 114 150 0.43 T 28-03-2018 hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 Gene3D G3DSA:2.40.50.100 45 113 8.9E-17 T 28-03-2018 hmeg3_RS13415 73d4856ebe775ae77f0878ed373239cf 295 Gene3D G3DSA:2.40.50.100 151 282 6.2E-7 T 28-03-2018 hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 Gene3D G3DSA:3.30.450.20 158 275 1.1E-14 T 28-03-2018 hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 Gene3D G3DSA:3.30.450.20 26 157 7.4E-10 T 28-03-2018 hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 SUPERFAMILY SSF55073 321 479 1.18E-44 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 SMART SM00267 305 480 2.0E-58 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 Pfam PF02743 Cache domain 37 262 3.9E-16 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 Gene3D G3DSA:3.30.70.270 304 483 2.1E-52 T 28-03-2018 hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 Pfam PF00990 Diguanylate cyclase, GGDEF domain 316 476 7.2E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19205 455cd74fdb34041e5175de8d7a45953d 498 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 312 479 5.7E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 Gene3D G3DSA:3.40.190.10 177 264 1.8E-20 T 28-03-2018 hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 Pfam PF03466 LysR substrate binding domain 89 294 2.6E-38 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 SUPERFAMILY SSF46785 4 111 1.87E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 Gene3D G3DSA:3.40.190.10 92 176 4.0E-17 T 28-03-2018 hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 9.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 SUPERFAMILY SSF53850 90 298 2.79E-43 T 28-03-2018 hmeg3_RS00010 9619a97fe58cf4954d4aecfa045242ff 299 Gene3D G3DSA:1.10.10.10 3 84 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08110 c5e5f1a93fc367a3a21fc812bc099762 574 Gene3D G3DSA:1.10.287.950 136 355 2.5E-40 T 28-03-2018 hmeg3_RS08110 c5e5f1a93fc367a3a21fc812bc099762 574 Gene3D G3DSA:1.10.287.950 50 135 0.0044 T 28-03-2018 hmeg3_RS08110 c5e5f1a93fc367a3a21fc812bc099762 574 SMART SM00283 89 350 6.7E-47 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08110 c5e5f1a93fc367a3a21fc812bc099762 574 SUPERFAMILY SSF58104 81 346 6.45E-52 T 28-03-2018 hmeg3_RS08110 c5e5f1a93fc367a3a21fc812bc099762 574 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 161 314 2.3E-38 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 Pfam PF00107 Zinc-binding dehydrogenase 156 251 2.5E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 Gene3D G3DSA:3.90.180.10 2 141 2.1E-33 T 28-03-2018 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 SMART SM00829 17 326 4.0E-25 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 Gene3D G3DSA:3.40.50.720 142 314 2.1E-30 T 28-03-2018 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 95 1.2E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 SUPERFAMILY SSF50129 16 146 1.05E-31 T 28-03-2018 IPR011032 GroES-like hmeg3_RS20790 30939781579df8b972bcb380da7794b1 328 SUPERFAMILY SSF51735 117 259 1.77E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06455 9a6eb7c62360cf9837acce3bad6d54fb 261 Gene3D G3DSA:3.40.50.10320 14 253 5.6E-39 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 hmeg3_RS06455 9a6eb7c62360cf9837acce3bad6d54fb 261 SUPERFAMILY SSF102588 49 259 5.75E-43 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 hmeg3_RS06455 9a6eb7c62360cf9837acce3bad6d54fb 261 Pfam PF02585 GlcNAc-PI de-N-acetylase 53 177 3.1E-21 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 hmeg3_RS14900 7db21e7eaf8c0a07a225dd227a58c7ed 153 SUPERFAMILY SSF50341 3 142 8.24E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14900 7db21e7eaf8c0a07a225dd227a58c7ed 153 Gene3D G3DSA:2.40.50.180 21 117 4.1E-14 T 28-03-2018 hmeg3_RS14900 7db21e7eaf8c0a07a225dd227a58c7ed 153 Pfam PF01584 CheW-like domain 3 140 4.9E-22 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14900 7db21e7eaf8c0a07a225dd227a58c7ed 153 SMART SM00260 1 138 4.3E-5 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS11365 fa73fda0d956e6bc8483ec68b4348aba 164 SUPERFAMILY SSF51316 1 154 1.36E-30 T 28-03-2018 IPR011057 Mss4-like hmeg3_RS11365 fa73fda0d956e6bc8483ec68b4348aba 164 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 26 112 3.9E-8 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 hmeg3_RS11365 fa73fda0d956e6bc8483ec68b4348aba 164 Gene3D G3DSA:3.90.1590.10 1 161 2.4E-29 T 28-03-2018 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Pfam PF01568 Molydopterin dinucleotide binding domain 603 714 9.1E-31 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 SUPERFAMILY SSF50692 575 718 1.45E-45 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 10 28 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Gene3D G3DSA:2.40.40.20 558 719 9.7E-45 T 28-03-2018 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Pfam PF04324 BFD-like [2Fe-2S] binding domain 852 900 1.8E-13 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 SMART SM00926 5 59 1.9E-16 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Gene3D G3DSA:3.40.50.740 65 255 3.2E-50 T 28-03-2018 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 SUPERFAMILY SSF53706 8 605 2.36E-189 T 28-03-2018 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Pfam PF00384 Molybdopterin oxidoreductase 62 492 3.7E-82 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Gene3D G3DSA:3.40.50.740 261 557 3.3E-76 T 28-03-2018 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 8 58 1.6E-16 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 Gene3D G3DSA:2.20.25.90 6 59 3.7E-17 T 28-03-2018 hmeg3_RS13205 d248825a7322509e8dab18fa3f897637 909 PIRSF PIRSF036643 3 725 3.6E-157 T 28-03-2018 hmeg3_RS11885 84a8ede89f83b44aaff56ac37e7af86e 329 SUPERFAMILY SSF56349 98 308 2.74E-37 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS11885 84a8ede89f83b44aaff56ac37e7af86e 329 Pfam PF00589 Phage integrase family 134 298 7.6E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS11885 84a8ede89f83b44aaff56ac37e7af86e 329 Gene3D G3DSA:1.10.150.130 2 99 7.8E-8 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS11885 84a8ede89f83b44aaff56ac37e7af86e 329 SUPERFAMILY SSF47823 7 98 3.92E-25 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal hmeg3_RS11885 84a8ede89f83b44aaff56ac37e7af86e 329 Gene3D G3DSA:1.10.443.10 100 301 1.4E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 SUPERFAMILY SSF55031 196 308 3.66E-29 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 PIRSF PIRSF005962 12 400 4.5E-122 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 SUPERFAMILY SSF53187 310 398 2.01E-80 T 28-03-2018 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 SUPERFAMILY SSF53187 15 209 2.01E-80 T 28-03-2018 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 Gene3D G3DSA:3.40.630.10 2 249 2.4E-49 T 28-03-2018 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 Gene3D G3DSA:3.40.630.10 250 400 2.9E-19 T 28-03-2018 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 Pfam PF07687 Peptidase dimerisation domain 197 292 5.4E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 386 9.6E-105 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS18860 921a4c5c15bbc75be437798929d8f620 402 Pfam PF01546 Peptidase family M20/M25/M40 84 395 4.2E-33 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS13705 ffedeaca14540e831c66a8161b3c688c 362 Gene3D G3DSA:3.40.50.1820 29 357 8.7E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS13705 ffedeaca14540e831c66a8161b3c688c 362 Pfam PF00561 alpha/beta hydrolase fold 72 329 6.4E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS13705 ffedeaca14540e831c66a8161b3c688c 362 PIRSF PIRSF000443 21 361 1.5E-56 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 hmeg3_RS13705 ffedeaca14540e831c66a8161b3c688c 362 SUPERFAMILY SSF53474 42 332 1.93E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 Gene3D G3DSA:3.40.50.1220 193 359 2.1E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 SUPERFAMILY SSF52518 3 186 5.61E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 Gene3D G3DSA:3.40.50.970 360 582 2.7E-42 T 28-03-2018 hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 590 0.0 T 28-03-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 2.2E-34 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 Gene3D G3DSA:3.40.50.970 1 192 6.5E-50 T 28-03-2018 hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 553 8.7E-34 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 SUPERFAMILY SSF52467 185 376 1.39E-46 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 SUPERFAMILY SSF52518 369 573 8.5E-52 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS17055 eeb4643e6b3f3b37c6df5944c684cd1c 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 1.8E-51 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 Pfam PF06472 ABC transporter transmembrane region 2 12 298 4.9E-68 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 SUPERFAMILY SSF52540 368 561 4.44E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 Pfam PF00005 ABC transporter 386 518 1.8E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 SUPERFAMILY SSF90123 12 342 6.15E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 SMART SM00382 393 565 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 Gene3D G3DSA:3.40.50.300 347 564 1.7E-38 T 28-03-2018 hmeg3_RS24110 cabfe99b7f9890c59cfa871c2928f479 580 Gene3D G3DSA:1.20.1560.10 10 346 4.0E-43 T 28-03-2018 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 341 82.892 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 Gene3D G3DSA:3.30.43.10 3 76 6.1E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 218 341 3.7E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 Gene3D G3DSA:3.90.78.10 233 341 1.3E-39 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 Gene3D G3DSA:3.30.465.10 77 230 5.5E-49 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 Pfam PF01565 FAD binding domain 36 157 8.8E-18 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 SUPERFAMILY SSF56194 214 341 1.14E-46 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 SUPERFAMILY SSF56176 10 199 2.18E-40 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS06855 65da6418ba088cc67545389e425a549c 341 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 13 340 1.1E-73 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS18090 215d4c9a6cb178e485d000109d3dcdc3 155 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 20 144 4.1E-31 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 hmeg3_RS18090 215d4c9a6cb178e485d000109d3dcdc3 155 PIRSF PIRSF003230 8 155 1.6E-44 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 hmeg3_RS18090 215d4c9a6cb178e485d000109d3dcdc3 155 Gene3D G3DSA:3.10.129.10 9 155 4.9E-40 T 28-03-2018 hmeg3_RS18090 215d4c9a6cb178e485d000109d3dcdc3 155 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 17 149 2.0E-48 T 28-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 hmeg3_RS18090 215d4c9a6cb178e485d000109d3dcdc3 155 Pfam PF03061 Thioesterase superfamily 31 113 1.8E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS18090 215d4c9a6cb178e485d000109d3dcdc3 155 SUPERFAMILY SSF54637 16 153 3.48E-41 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS11090 01bc91798e7050656ed5369e227965bd 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 309 1.4E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11090 01bc91798e7050656ed5369e227965bd 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 67 2.2E-10 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS11090 01bc91798e7050656ed5369e227965bd 311 Gene3D G3DSA:1.10.3720.10 21 300 6.2E-46 T 28-03-2018 hmeg3_RS11090 01bc91798e7050656ed5369e227965bd 311 SUPERFAMILY SSF161098 103 296 8.5E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Pfam PF00072 Response regulator receiver domain 471 582 1.3E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Gene3D G3DSA:3.30.450.20 180 224 6.6E-6 T 28-03-2018 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 SMART SM00448 469 583 2.0E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Gene3D G3DSA:3.40.50.2300 460 593 7.8E-22 T 28-03-2018 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Gene3D G3DSA:3.30.565.10 271 444 2.2E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Gene3D G3DSA:1.10.287.130 225 270 1.3E-10 T 28-03-2018 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 SMART SM00387 333 446 1.6E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 SUPERFAMILY SSF47384 202 289 3.53E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 219 289 1.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 443 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 SMART SM00388 219 289 3.6E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 SUPERFAMILY SSF52172 470 588 2.7E-22 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23665 0df45bbd29430e9dc393b9e4eb3c47a9 593 SUPERFAMILY SSF55874 280 444 1.31E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 Gene3D G3DSA:2.40.50.140 291 353 7.1E-9 T 28-03-2018 hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 Gene3D G3DSA:3.40.50.300 4 255 1.8E-71 T 28-03-2018 hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 Pfam PF08402 TOBE domain 288 358 1.9E-10 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 SUPERFAMILY SSF50331 259 360 1.8E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 SUPERFAMILY SSF52540 8 257 2.66E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 Pfam PF00005 ABC transporter 32 174 4.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14410 7c0574ee360187ba72cc8b2242d2f723 366 SMART SM00382 41 224 9.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS20260 a7cd54529d802031c23ad2d4761428da 471 SUPERFAMILY SSF56059 45 210 1.36E-64 T 28-03-2018 hmeg3_RS20260 a7cd54529d802031c23ad2d4761428da 471 SUPERFAMILY SSF56059 317 462 1.36E-64 T 28-03-2018 hmeg3_RS20260 a7cd54529d802031c23ad2d4761428da 471 Pfam PF14403 Circularly permuted ATP-grasp type 2 72 447 1.3E-164 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 hmeg3_RS20260 a7cd54529d802031c23ad2d4761428da 471 Gene3D G3DSA:3.30.470.20 336 460 1.2E-5 T 28-03-2018 hmeg3_RS20260 a7cd54529d802031c23ad2d4761428da 471 PIRSF PIRSF005522 1 471 1.1E-233 T 28-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 hmeg3_RS08440 abb0c46142075e653bfd83839bad7025 318 Gene3D G3DSA:3.90.550.10 1 226 8.6E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS08440 abb0c46142075e653bfd83839bad7025 318 SUPERFAMILY SSF53448 2 254 1.33E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS08440 abb0c46142075e653bfd83839bad7025 318 Pfam PF00535 Glycosyl transferase family 2 6 151 6.1E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Pfam PF12344 Ultra-violet resistance protein B 573 615 6.7E-20 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 SMART SM00487 31 447 1.5E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 SMART SM00490 481 567 1.2E-20 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Pfam PF02151 UvrB/uvrC motif 650 684 7.4E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 SUPERFAMILY SSF52540 480 605 6.09E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 SUPERFAMILY SSF52540 59 104 6.09E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Pfam PF00271 Helicase conserved C-terminal domain 457 565 3.3E-19 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 27 682 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Gene3D G3DSA:4.10.860.10 628 689 6.9E-17 T 28-03-2018 IPR001943 UVR domain GO:0005515 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Pfam PF04851 Type III restriction enzyme, res subunit 39 160 1.4E-8 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 SUPERFAMILY SSF46600 639 686 1.57E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 SUPERFAMILY SSF52540 27 436 7.91E-132 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Gene3D G3DSA:3.40.50.300 436 610 7.1E-31 T 28-03-2018 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Hamap MF_00204 UvrABC system protein B [uvrB]. 25 684 42.624 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 hmeg3_RS08055 f5afa00f17ee9061a200776682a0d5e1 697 Gene3D G3DSA:3.40.50.300 32 435 1.4E-30 T 28-03-2018 hmeg3_RS06490 97b3e9547c276660dced4198b7d405ce 489 Pfam PF02321 Outer membrane efflux protein 86 275 8.9E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS06490 97b3e9547c276660dced4198b7d405ce 489 Pfam PF02321 Outer membrane efflux protein 301 484 4.6E-29 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS06490 97b3e9547c276660dced4198b7d405ce 489 Gene3D G3DSA:1.20.1600.10 35 489 8.4E-93 T 28-03-2018 hmeg3_RS06490 97b3e9547c276660dced4198b7d405ce 489 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 26 486 8.0E-120 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS06490 97b3e9547c276660dced4198b7d405ce 489 SUPERFAMILY SSF56954 76 488 6.93E-105 T 28-03-2018 hmeg3_RS06490 97b3e9547c276660dced4198b7d405ce 489 SUPERFAMILY SSF56954 19 47 6.93E-105 T 28-03-2018 hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 Pfam PF00691 OmpA family 72 167 6.7E-20 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 SUPERFAMILY SSF103088 63 173 2.22E-31 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 ProSitePatterns PS01068 OmpA-like domain. 105 149 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 Gene3D G3DSA:3.30.1330.60 24 174 4.1E-31 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 PRINTS PR01021 OMPA domain signature 73 95 2.9E-15 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 PRINTS PR01021 OMPA domain signature 103 118 2.9E-15 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 PRINTS PR01021 OMPA domain signature 118 134 2.9E-15 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS18115 076a59960ddb4a68359697a8dfd84d2c 174 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 70 173 3.7E-42 T 28-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 hmeg3_RS12220 318ba16f7d750edb259ef9eadad5b08d 268 SUPERFAMILY SSF54001 49 251 8.97E-43 T 28-03-2018 hmeg3_RS12220 318ba16f7d750edb259ef9eadad5b08d 268 Gene3D G3DSA:3.90.260.10 146 231 1.4E-7 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS12220 318ba16f7d750edb259ef9eadad5b08d 268 Pfam PF01841 Transglutaminase-like superfamily 125 225 3.5E-20 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS12220 318ba16f7d750edb259ef9eadad5b08d 268 SMART SM00460 161 227 5.7E-13 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS21920 264f84d494bba7ae352e6031ea6ede9f 214 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 13 195 2.6E-50 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 hmeg3_RS21920 264f84d494bba7ae352e6031ea6ede9f 214 Gene3D G3DSA:3.40.50.300 3 213 1.9E-37 T 28-03-2018 hmeg3_RS21920 264f84d494bba7ae352e6031ea6ede9f 214 Pfam PF01121 Dephospho-CoA kinase 13 186 1.5E-58 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 hmeg3_RS21920 264f84d494bba7ae352e6031ea6ede9f 214 SUPERFAMILY SSF52540 11 204 5.33E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21920 264f84d494bba7ae352e6031ea6ede9f 214 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 10 205 27.002 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 hmeg3_RS05740 0ffb35ecb6f98797f694dfeee5b58f43 334 SUPERFAMILY SSF46689 32 106 2.33E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05740 0ffb35ecb6f98797f694dfeee5b58f43 334 Pfam PF01380 SIS domain 160 285 2.0E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS05740 0ffb35ecb6f98797f694dfeee5b58f43 334 Pfam PF01418 Helix-turn-helix domain, rpiR family 36 101 4.8E-7 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 hmeg3_RS05740 0ffb35ecb6f98797f694dfeee5b58f43 334 SUPERFAMILY SSF53697 130 290 8.45E-14 T 28-03-2018 hmeg3_RS05740 0ffb35ecb6f98797f694dfeee5b58f43 334 Gene3D G3DSA:1.10.10.10 26 100 9.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05740 0ffb35ecb6f98797f694dfeee5b58f43 334 Gene3D G3DSA:3.40.50.10490 101 310 1.3E-12 T 28-03-2018 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 Pfam PF00311 Phosphoenolpyruvate carboxylase 164 965 1.3E-296 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 167 178 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 Gene3D G3DSA:1.20.1440.90 312 436 2.4E-23 T 28-03-2018 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 SUPERFAMILY SSF51621 38 965 2.83E-300 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 29 965 19.396 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 605 617 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 166 179 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 783 809 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 603 623 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 283 298 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 218 234 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 645 674 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS16910 70882b5ff884de34eee18fb82c714c76 965 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 434 454 5.3E-55 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 hmeg3_RS05965 8e86e430d3e4b0f2a165acfb71ffc2ed 183 SUPERFAMILY SSF54427 56 181 2.37E-33 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS05965 8e86e430d3e4b0f2a165acfb71ffc2ed 183 Pfam PF07366 SnoaL-like polyketide cyclase 55 178 2.2E-39 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS05965 8e86e430d3e4b0f2a165acfb71ffc2ed 183 Gene3D G3DSA:3.10.450.50 38 181 1.5E-26 T 28-03-2018 hmeg3_RS09755 0cca2f802d459e7f04c49a56d695475d 90 Pfam PF13663 Domain of unknown function (DUF4148) 1 60 5.7E-15 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 SUPERFAMILY SSF51735 162 356 4.86E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 144 1.8E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 Gene3D G3DSA:3.90.180.10 5 183 4.1E-37 T 28-03-2018 hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 Pfam PF00107 Zinc-binding dehydrogenase 197 265 3.5E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 SUPERFAMILY SSF50129 4 188 1.1E-62 T 28-03-2018 IPR011032 GroES-like hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 3 395 1.2E-229 T 28-03-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 hmeg3_RS19390 bd1c13d411aa1f430187d30dc585ddca 398 Gene3D G3DSA:3.40.50.720 184 338 6.0E-25 T 28-03-2018 hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Gene3D G3DSA:3.40.190.10 46 168 2.0E-23 T 28-03-2018 hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 323 436 3.3E-11 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 443 606 4.7E-40 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Gene3D G3DSA:3.20.20.450 615 867 5.0E-91 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Pfam PF13426 PAS domain 330 432 3.3E-13 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 269 1.4E-29 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SMART SM00086 391 433 7.1E-5 T 28-03-2018 IPR001610 PAC motif hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Gene3D G3DSA:3.30.450.20 299 441 4.5E-21 T 28-03-2018 hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SUPERFAMILY SSF141868 625 865 4.84E-86 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SMART SM00052 618 864 5.8E-109 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Gene3D G3DSA:3.30.70.270 442 614 1.0E-52 T 28-03-2018 hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SUPERFAMILY SSF53850 50 269 2.51E-39 T 28-03-2018 hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Pfam PF00990 Diguanylate cyclase, GGDEF domain 444 604 3.3E-44 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Gene3D G3DSA:3.40.190.10 169 277 1.6E-9 T 28-03-2018 hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SMART SM00267 433 608 1.3E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SMART SM00062 49 272 2.2E-31 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SUPERFAMILY SSF55785 328 433 6.28E-20 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 Pfam PF00563 EAL domain 625 859 9.1E-71 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13115 8333bf10cda57942adf10b66bcd4bb46 867 SUPERFAMILY SSF55073 449 608 7.45E-44 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 PIRSF PIRSF001500 1 358 6.3E-142 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Gene3D G3DSA:3.40.190.10 99 179 9.1E-32 T 28-03-2018 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Gene3D G3DSA:3.40.190.10 180 255 2.9E-24 T 28-03-2018 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 304 311 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Pfam PF01817 Chorismate mutase type II 11 88 4.1E-26 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 SMART SM00830 11 90 2.3E-34 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 SUPERFAMILY SSF53850 92 274 1.19E-56 T 28-03-2018 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 TIGRFAM TIGR01807 CM_P2: chorismate mutase 7 80 6.6E-28 T 28-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Gene3D G3DSA:3.30.70.260 268 358 1.1E-28 T 28-03-2018 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Gene3D G3DSA:1.20.59.10 1 98 7.7E-38 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Pfam PF01842 ACT domain 278 341 3.8E-8 T 28-03-2018 IPR002912 ACT domain hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 SUPERFAMILY SSF55021 261 356 9.51E-26 T 28-03-2018 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 SUPERFAMILY SSF48600 6 94 5.68E-23 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS17990 fe563c4d72404bdc717eeba7a88216af 358 Pfam PF00800 Prephenate dehydratase 92 266 5.8E-61 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 hmeg3_RS15230 9d52be88ec656d4c3f1c62f4d35d1a3f 68 Pfam PF11943 Protein of unknown function (DUF3460) 9 67 5.8E-28 T 28-03-2018 IPR021853 Protein of unknown function DUF3460 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 189 1.2E-53 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Gene3D G3DSA:1.10.150.20 82 120 4.7E-17 T 28-03-2018 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 SMART SM00278 108 127 0.0011 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 SMART SM00278 73 92 1.8 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Pfam PF01330 RuvA N terminal domain 1 62 6.9E-20 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Pfam PF07499 RuvA, C-terminal domain 148 190 6.0E-12 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 190 30.82 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Gene3D G3DSA:1.10.340.30 56 81 0.16 T 28-03-2018 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Gene3D G3DSA:2.40.50.140 1 55 3.8E-23 T 28-03-2018 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Gene3D G3DSA:1.10.150.20 121 146 0.032 T 28-03-2018 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 SUPERFAMILY SSF46929 146 191 2.49E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 SUPERFAMILY SSF50249 1 63 2.06E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Gene3D G3DSA:1.10.8.10 147 192 3.4E-11 T 28-03-2018 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 Pfam PF14520 Helix-hairpin-helix domain 72 129 1.6E-18 T 28-03-2018 hmeg3_RS21630 f950f1016018c7714a50f4dfd85eb6f6 192 SUPERFAMILY SSF47781 66 133 5.72E-21 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS23115 c712abe652fdaf312388804c2d7550e0 131 Gene3D G3DSA:3.10.450.50 10 129 1.1E-12 T 28-03-2018 hmeg3_RS23115 c712abe652fdaf312388804c2d7550e0 131 SUPERFAMILY SSF54427 10 129 1.48E-29 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS23115 c712abe652fdaf312388804c2d7550e0 131 Pfam PF12893 Putative lumazine-binding 15 127 3.2E-26 T 28-03-2018 hmeg3_RS14455 33954d2ef20f0bf15c3139f32c352d41 260 Pfam PF00005 ABC transporter 21 151 3.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14455 33954d2ef20f0bf15c3139f32c352d41 260 SMART SM00382 30 201 3.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14455 33954d2ef20f0bf15c3139f32c352d41 260 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS14455 33954d2ef20f0bf15c3139f32c352d41 260 SUPERFAMILY SSF52540 8 213 6.74E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14455 33954d2ef20f0bf15c3139f32c352d41 260 Gene3D G3DSA:3.40.50.300 4 220 2.3E-58 T 28-03-2018 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 Pfam PF00231 ATP synthase 5 288 2.6E-94 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 275 288 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 Gene3D G3DSA:1.10.287.80 180 270 2.2E-29 T 28-03-2018 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 4.6E-105 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 SUPERFAMILY SSF52943 2 289 1.44E-92 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 Gene3D G3DSA:1.10.287.80 2 60 1.5E-17 T 28-03-2018 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 4.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 4.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 4.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 4.8E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 35.591 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02440 e7c519e252bbd86903658e0a5608d6f3 289 Gene3D G3DSA:3.40.1380.10 63 179 1.0E-36 T 28-03-2018 hmeg3_RS06190 94f75ca113b5a58456fefdf87e71b70b 261 SMART SM00382 39 249 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06190 94f75ca113b5a58456fefdf87e71b70b 261 SUPERFAMILY SSF52540 14 247 3.96E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06190 94f75ca113b5a58456fefdf87e71b70b 261 Pfam PF00005 ABC transporter 30 186 3.2E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06190 94f75ca113b5a58456fefdf87e71b70b 261 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06190 94f75ca113b5a58456fefdf87e71b70b 261 Gene3D G3DSA:3.40.50.300 1 259 3.7E-61 T 28-03-2018 hmeg3_RS06190 94f75ca113b5a58456fefdf87e71b70b 261 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 15 261 2.0E-119 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 hmeg3_RS14320 7c03a38c3be9bc29ecc20bc5fb2b283c 241 PIRSF PIRSF037208 4 241 1.7E-93 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 hmeg3_RS14320 7c03a38c3be9bc29ecc20bc5fb2b283c 241 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 2.8E-19 T 28-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 hmeg3_RS14320 7c03a38c3be9bc29ecc20bc5fb2b283c 241 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 3 241 45.737 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 hmeg3_RS14320 7c03a38c3be9bc29ecc20bc5fb2b283c 241 Gene3D G3DSA:3.40.630.30 84 229 1.6E-5 T 28-03-2018 hmeg3_RS14320 7c03a38c3be9bc29ecc20bc5fb2b283c 241 SUPERFAMILY SSF55729 85 237 5.82E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS14320 7c03a38c3be9bc29ecc20bc5fb2b283c 241 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 232 2.5E-40 T 28-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 hmeg3_RS14620 b7e59dc8730097e30b31f9d40569827b 174 Gene3D G3DSA:2.60.40.1090 25 174 3.1E-34 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS14620 b7e59dc8730097e30b31f9d40569827b 174 SUPERFAMILY SSF49401 26 174 1.14E-28 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS14620 b7e59dc8730097e30b31f9d40569827b 174 Pfam PF16970 Type-1 fimbrial protein, A 51 173 2.0E-19 T 28-03-2018 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SUPERFAMILY SSF158472 318 364 1.7E-8 T 28-03-2018 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Gene3D G3DSA:3.30.450.20 367 533 2.0E-14 T 28-03-2018 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Pfam PF00512 His Kinase A (phospho-acceptor) domain 539 606 1.4E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 650 766 3.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Gene3D G3DSA:1.10.287.130 534 606 6.5E-10 T 28-03-2018 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SUPERFAMILY SSF47384 535 607 5.69E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Pfam PF13188 PAS domain 381 426 1.9E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 728 1.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 714 1.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 729 747 1.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SUPERFAMILY SSF55874 600 766 4.19E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Gene3D G3DSA:1.20.1250.20 2 321 6.2E-4 T 28-03-2018 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Pfam PF00672 HAMP domain 317 362 3.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SMART SM00304 315 367 3.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SMART SM00388 538 610 1.7E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SUPERFAMILY SSF55785 367 438 3.66E-9 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 PIRSF PIRSF037532 1 773 9.3E-219 T 28-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 SMART SM00387 650 770 1.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23070 6393f157ddfd8317b76b2fdd14e0d197 773 Gene3D G3DSA:3.30.565.10 611 772 2.1E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 Gene3D G3DSA:3.40.50.2300 1 123 5.8E-31 T 28-03-2018 hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 Gene3D G3DSA:1.10.10.60 179 240 7.0E-13 T 28-03-2018 hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 SMART SM00448 2 114 3.7E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 Pfam PF02954 Bacterial regulatory protein, Fis family 194 233 3.4E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 SUPERFAMILY SSF46689 159 235 4.03E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 SUPERFAMILY SSF52172 1 130 8.4E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23075 a01761e13a81f5b6ec666f4c15381605 245 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12115 080eb03689ccfd3ebd17c9e02afa1dff 119 SUPERFAMILY SSF56601 15 113 1.22E-11 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS12115 080eb03689ccfd3ebd17c9e02afa1dff 119 Gene3D G3DSA:3.40.710.10 2 116 1.0E-9 T 28-03-2018 hmeg3_RS12115 080eb03689ccfd3ebd17c9e02afa1dff 119 Pfam PF00144 Beta-lactamase 19 86 4.1E-10 T 28-03-2018 IPR001466 Beta-lactamase-related hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 SUPERFAMILY SSF46785 5 78 1.47E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 Pfam PF09339 IclR helix-turn-helix domain 7 55 5.3E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 Gene3D G3DSA:3.30.450.40 77 251 4.8E-40 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 SUPERFAMILY SSF55781 70 250 2.42E-41 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 SMART SM00346 5 94 1.4E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 Pfam PF01614 Bacterial transcriptional regulator 122 244 2.1E-28 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS09550 c93474f81781a01c3201919e41bd41e8 253 Gene3D G3DSA:1.10.10.10 2 65 9.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10195 d6203d3f73763d8e07199c478c612c7e 232 Gene3D G3DSA:3.40.50.2300 27 149 8.4E-21 T 28-03-2018 hmeg3_RS10195 d6203d3f73763d8e07199c478c612c7e 232 SMART SM00448 27 139 2.1E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10195 d6203d3f73763d8e07199c478c612c7e 232 SUPERFAMILY SSF52172 29 155 2.56E-20 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10195 d6203d3f73763d8e07199c478c612c7e 232 Pfam PF00072 Response regulator receiver domain 29 139 4.9E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10195 d6203d3f73763d8e07199c478c612c7e 232 SUPERFAMILY SSF46894 162 220 1.05E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS10195 d6203d3f73763d8e07199c478c612c7e 232 Gene3D G3DSA:1.10.10.10 150 232 6.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 257 286 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 Gene3D G3DSA:3.40.50.20 1 104 9.9E-38 T 28-03-2018 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 Pfam PF01820 D-ala D-ala ligase N-terminus 12 93 1.1E-20 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 SUPERFAMILY SSF52440 12 104 3.84E-31 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 Gene3D G3DSA:3.30.470.20 178 323 1.8E-41 T 28-03-2018 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 SUPERFAMILY SSF56059 104 320 6.01E-54 T 28-03-2018 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 Gene3D G3DSA:3.30.1490.20 105 177 1.4E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 12 315 1.2E-98 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 Pfam PF07478 D-ala D-ala ligase C-terminus 114 312 3.3E-57 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 71 82 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 11 316 35.381 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 PIRSF PIRSF039102 49 323 1.4E-84 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22000 484b50fb8fd2e78906b4d91165dff03e 341 PIRSF PIRSF039102 8 53 8.0E-9 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS17365 3cfc9402c9bcb0ea44561f15d44d773d 286 SUPERFAMILY SSF52540 6 222 7.81E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17365 3cfc9402c9bcb0ea44561f15d44d773d 286 SMART SM00382 32 214 4.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17365 3cfc9402c9bcb0ea44561f15d44d773d 286 Gene3D G3DSA:3.40.50.300 1 262 1.5E-60 T 28-03-2018 hmeg3_RS17365 3cfc9402c9bcb0ea44561f15d44d773d 286 Pfam PF00005 ABC transporter 24 164 3.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS17365 3cfc9402c9bcb0ea44561f15d44d773d 286 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 Pfam PF05199 GMC oxidoreductase 394 531 4.3E-37 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 Gene3D G3DSA:3.40.50.720 2 40 0.0022 T 28-03-2018 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 Gene3D G3DSA:4.10.450.10 41 106 1.9E-28 T 28-03-2018 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 PIRSF PIRSF000137 1 542 5.1E-147 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 SUPERFAMILY SSF51905 6 295 1.02E-89 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 SUPERFAMILY SSF51905 479 540 1.02E-89 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 261 275 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 Pfam PF00732 GMC oxidoreductase 7 302 9.1E-77 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 SUPERFAMILY SSF54373 297 480 3.63E-53 T 28-03-2018 hmeg3_RS24220 31ec38bb8696fa442628a041d266a063 542 Gene3D G3DSA:3.30.560.10 107 495 3.0E-94 T 28-03-2018 hmeg3_RS10185 e4d5a5d57595cfafce3f56154ba4f6a0 400 SUPERFAMILY SSF56935 21 89 2.32E-47 T 28-03-2018 hmeg3_RS10185 e4d5a5d57595cfafce3f56154ba4f6a0 400 SUPERFAMILY SSF56935 125 400 2.32E-47 T 28-03-2018 hmeg3_RS10185 e4d5a5d57595cfafce3f56154ba4f6a0 400 Pfam PF13609 Gram-negative porin 17 366 1.2E-39 T 28-03-2018 hmeg3_RS10185 e4d5a5d57595cfafce3f56154ba4f6a0 400 Gene3D G3DSA:2.40.160.10 10 399 3.8E-54 T 28-03-2018 hmeg3_RS03505 938916040dcc4a01fef7923bf719ffb3 268 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 244 1.1E-73 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 hmeg3_RS03505 938916040dcc4a01fef7923bf719ffb3 268 SUPERFAMILY SSF51366 1 246 3.06E-72 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS03505 938916040dcc4a01fef7923bf719ffb3 268 Pfam PF00977 Histidine biosynthesis protein 3 240 8.2E-77 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 hmeg3_RS03505 938916040dcc4a01fef7923bf719ffb3 268 Gene3D G3DSA:3.20.20.70 2 252 9.4E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS03505 938916040dcc4a01fef7923bf719ffb3 268 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 248 35.176 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 41.831 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 250 4.9E-96 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 3.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 3.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 3.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 3.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 SUPERFAMILY SSF55920 4 253 4.06E-93 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 Pfam PF00557 Metallopeptidase family M24 13 242 2.1E-53 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS05875 8363642fdd2d5d7be80cb21f9ec34d01 254 Gene3D G3DSA:3.90.230.10 2 254 1.2E-87 T 28-03-2018 hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.7E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 2.7E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 2.7E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 Gene3D G3DSA:1.10.10.10 2 99 4.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 SUPERFAMILY SSF46785 7 96 9.97E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 Pfam PF12840 Helix-turn-helix domain 12 72 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02330 3f3dccaa6434e175bcfc102b944d7809 115 SMART SM00418 11 88 8.3E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 Gene3D G3DSA:3.30.420.40 8 173 3.9E-40 T 28-03-2018 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 Pfam PF06723 MreB/Mbl protein 10 340 8.8E-150 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 SUPERFAMILY SSF53067 154 339 2.71E-49 T 28-03-2018 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 SUPERFAMILY SSF53067 9 153 6.18E-37 T 28-03-2018 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 2.0E-156 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 5.4E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 5.4E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 5.4E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 5.4E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 5.4E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 Gene3D G3DSA:3.90.640.10 191 257 1.8E-28 T 28-03-2018 hmeg3_RS00715 aad8bdcb3bbe93afffbf5fe3a7a0573f 347 Gene3D G3DSA:3.30.420.40 258 322 8.7E-9 T 28-03-2018 hmeg3_RS10070 d05813a8936aa29565d8f3732673ef2a 102 Pfam PF03658 RnfH family Ubiquitin 13 94 1.1E-30 T 28-03-2018 IPR005346 RnfH protein hmeg3_RS10070 d05813a8936aa29565d8f3732673ef2a 102 SUPERFAMILY SSF54285 11 86 9.81E-24 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp hmeg3_RS10070 d05813a8936aa29565d8f3732673ef2a 102 Gene3D G3DSA:3.10.20.280 6 95 1.1E-31 T 28-03-2018 IPR005346 RnfH protein hmeg3_RS10070 d05813a8936aa29565d8f3732673ef2a 102 Hamap MF_00460 Protein RnfH [rnfH]. 12 102 23.026 T 28-03-2018 IPR005346 RnfH protein hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.40.50.980 1610 1777 3.4E-42 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.40.50.980 1778 1937 1.1E-29 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.40.50.980 679 839 1.2E-41 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 1156 1326 1.01E-42 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1062 1077 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.40.50.1820 3251 3527 3.5E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF47336 3164 3241 7.85E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 2413 2660 1.22E-42 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:1.10.1200.10 2149 2210 2.8E-20 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 1328 1582 2.22E-51 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 2691 2888 1.56E-37 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00550 Phosphopantetheine attachment site 1039 1100 1.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00550 Phosphopantetheine attachment site 3172 3240 8.2E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00550 Phosphopantetheine attachment site 2145 2204 2.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:1.10.1200.10 1042 1113 5.1E-21 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:1.10.1200.10 3164 3244 5.9E-14 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.40.50.980 513 678 1.1E-44 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF13193 AMP-binding enzyme C-terminal domain 2039 2113 5.5E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF13193 AMP-binding enzyme C-terminal domain 939 1013 2.7E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF56801 479 1051 5.23E-165 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 243 484 7.23E-57 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2532 2682 1.1E-38 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.30.559.10 1131 1337 2.5E-38 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF56801 1577 2150 2.22E-141 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF47336 1030 1100 2.36E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00501 AMP-binding enzyme 1618 2030 7.5E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00501 AMP-binding enzyme 531 931 4.9E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF53474 3260 3522 2.67E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.30.559.10 2211 2428 7.3E-35 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.30.559.10 32 257 1.8E-35 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.30.559.10 2685 2893 5.3E-37 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 2877 3131 1.78E-46 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2167 2182 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 2227 2402 1.56E-39 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:2.30.38.10 1940 2021 1.5E-21 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:2.30.38.10 840 921 2.6E-24 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00975 Thioesterase domain 3268 3370 4.3E-9 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 543 955 2.7E-140 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1639 2055 2.7E-118 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.30.300.30 926 1041 2.5E-36 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Gene3D G3DSA:3.30.300.30 2026 2148 7.1E-36 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 674 685 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00668 Condensation domain 1153 1599 2.3E-84 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00668 Condensation domain 2695 3135 4.5E-66 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00668 Condensation domain 2228 2660 2.3E-80 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 Pfam PF00668 Condensation domain 43 501 7.5E-93 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF52777 45 235 3.72E-39 T 28-03-2018 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SUPERFAMILY SSF47336 2138 2204 3.14E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SMART SM00823 Phosphopantetheine attachment site 3169 3245 0.019 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SMART SM00823 Phosphopantetheine attachment site 2143 2211 0.0016 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 SMART SM00823 Phosphopantetheine attachment site 1038 1106 0.015 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11660 ebaa71e8092cf9b14f99b5beba9eda0f 3527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1772 1783 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS19880 0984db069df63292dccc970186439052 678 Pfam PF02378 Phosphotransferase system, EIIC 68 314 1.2E-13 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 hmeg3_RS19880 0984db069df63292dccc970186439052 678 Pfam PF00563 EAL domain 428 651 3.0E-55 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19880 0984db069df63292dccc970186439052 678 SUPERFAMILY SSF141868 428 662 1.44E-60 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19880 0984db069df63292dccc970186439052 678 SMART SM00052 411 657 1.5E-59 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19880 0984db069df63292dccc970186439052 678 Gene3D G3DSA:3.20.20.450 408 661 1.3E-64 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19740 5096e80babe96c091bea9be8fb09e8bc 164 SUPERFAMILY SSF52540 28 142 1.78E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19740 5096e80babe96c091bea9be8fb09e8bc 164 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 12 136 8.8E-36 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 hmeg3_RS19740 5096e80babe96c091bea9be8fb09e8bc 164 Gene3D G3DSA:3.40.50.300 4 160 1.4E-46 T 28-03-2018 hmeg3_RS19740 5096e80babe96c091bea9be8fb09e8bc 164 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 11 147 6.9E-37 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 hmeg3_RS19365 b02c212e930615d890199c7a07c76bef 367 Gene3D G3DSA:3.90.380.10 124 358 2.0E-34 T 28-03-2018 hmeg3_RS19365 b02c212e930615d890199c7a07c76bef 367 Gene3D G3DSA:2.102.10.10 21 123 3.1E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS19365 b02c212e930615d890199c7a07c76bef 367 SUPERFAMILY SSF55961 122 356 8.61E-35 T 28-03-2018 hmeg3_RS19365 b02c212e930615d890199c7a07c76bef 367 SUPERFAMILY SSF50022 19 129 3.27E-31 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS19365 b02c212e930615d890199c7a07c76bef 367 Pfam PF00355 Rieske [2Fe-2S] domain 24 104 6.8E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 Gene3D G3DSA:3.90.1150.10 2 190 6.5E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 Gene3D G3DSA:3.40.640.10 191 327 7.3E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 Pfam PF00202 Aminotransferase class-III 27 436 2.5E-94 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 SUPERFAMILY SSF53383 1 438 1.05E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 Gene3D G3DSA:3.90.1150.10 328 440 1.4E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 PIRSF PIRSF000521 178 439 2.6E-20 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS00835 e99d463fb8ba3a1fe2fe92cb572b9d91 440 PIRSF PIRSF000521 24 143 5.5E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 195 8.5E-4 T 28-03-2018 hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 Gene3D G3DSA:3.40.50.720 1 257 2.5E-76 T 28-03-2018 hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 1.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 SUPERFAMILY SSF51735 13 256 6.2E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 254 2.6E-67 T 28-03-2018 hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16735 40a84bd5acf94fd6a491c7ee778a6d8d 257 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 17 255 3.3E-98 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 Pfam PF00206 Lyase 116 318 3.8E-31 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00149 Fumarate lyase superfamily signature 293 309 4.1E-9 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 4.1E-9 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 4.1E-9 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 Gene3D G3DSA:1.20.200.10 118 385 1.5E-50 T 28-03-2018 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 Pfam PF14698 Argininosuccinate lyase C-terminal 378 439 1.2E-9 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 Gene3D G3DSA:1.10.40.30 386 462 1.7E-11 T 28-03-2018 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00145 Argininosuccinate lyase family signature 157 177 1.3E-21 T 28-03-2018 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00145 Argininosuccinate lyase family signature 116 138 1.3E-21 T 28-03-2018 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00145 Argininosuccinate lyase family signature 208 224 1.3E-21 T 28-03-2018 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 PRINTS PR00145 Argininosuccinate lyase family signature 293 309 1.3E-21 T 28-03-2018 hmeg3_RS20685 54678cf61c8462f54dabcc9a1e9139eb 515 SUPERFAMILY SSF48557 49 485 2.36E-70 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS23680 fab89a9f9fa3fd46eda9e4882d1db1a7 486 SUPERFAMILY SSF48452 73 167 3.72E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23680 fab89a9f9fa3fd46eda9e4882d1db1a7 486 SUPERFAMILY SSF56935 331 486 9.61E-10 T 28-03-2018 hmeg3_RS23680 fab89a9f9fa3fd46eda9e4882d1db1a7 486 Gene3D G3DSA:1.25.40.10 61 186 1.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23680 fab89a9f9fa3fd46eda9e4882d1db1a7 486 Gene3D G3DSA:2.40.160.20 189 384 1.8E-8 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS23680 fab89a9f9fa3fd46eda9e4882d1db1a7 486 Pfam PF04575 Protein of unknown function (DUF560) 194 470 2.2E-14 T 28-03-2018 IPR007655 Protein of unknown function DUF560 hmeg3_RS23680 fab89a9f9fa3fd46eda9e4882d1db1a7 486 Gene3D G3DSA:2.40.160.20 385 486 5.9E-5 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 SUPERFAMILY SSF46785 4 87 4.36E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 Pfam PF03466 LysR substrate binding domain 88 295 1.8E-39 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 SUPERFAMILY SSF53850 89 298 1.03E-37 T 28-03-2018 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 Gene3D G3DSA:3.40.190.10 176 266 1.0E-20 T 28-03-2018 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 Gene3D G3DSA:1.10.10.10 2 84 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04420 47db8f11b0ca2375d3563ffb3e0655e9 310 Gene3D G3DSA:3.40.190.10 88 175 9.8E-13 T 28-03-2018 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 Gene3D G3DSA:3.40.50.10230 301 516 8.9E-66 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 Pfam PF02570 Precorrin-8X methylmutase 306 500 2.0E-61 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 Gene3D G3DSA:3.40.50.1400 120 248 5.2E-25 T 28-03-2018 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 SUPERFAMILY SSF53800 1 247 1.74E-52 T 28-03-2018 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 Pfam PF01903 CbiX 136 239 3.4E-20 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 Pfam PF01903 CbiX 6 110 1.6E-21 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 SUPERFAMILY SSF63965 302 501 6.15E-61 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 hmeg3_RS12425 616e36bc5a6ba6c743d56a8acd5c3e2c 521 Gene3D G3DSA:3.40.50.1400 1 104 9.0E-25 T 28-03-2018 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 Pfam PF00158 Sigma-54 interaction domain 148 314 9.9E-72 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 SUPERFAMILY SSF46689 401 449 3.72E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 SMART SM00382 168 311 4.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 Gene3D G3DSA:1.10.10.60 389 451 2.1E-8 T 28-03-2018 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 SMART SM00448 9 120 7.8E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 Pfam PF00072 Response regulator receiver domain 12 120 7.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 Gene3D G3DSA:1.10.8.60 321 388 1.3E-21 T 28-03-2018 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 SUPERFAMILY SSF52172 7 192 4.84E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 Gene3D G3DSA:3.40.50.2300 1 139 5.0E-32 T 28-03-2018 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 Gene3D G3DSA:3.40.50.300 143 320 7.4E-26 T 28-03-2018 hmeg3_RS00235 0736ca7a5610b307de58f2707cfdb0bf 467 SUPERFAMILY SSF52540 148 392 7.06E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Pfam PF00679 Elongation factor G C-terminus 402 484 2.1E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Gene3D G3DSA:3.40.50.300 71 191 1.3E-29 T 28-03-2018 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 SMART SM00838 403 488 0.0019 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Pfam PF03144 Elongation factor Tu domain 2 222 293 8.0E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Gene3D G3DSA:3.40.50.300 1 70 3.3E-11 T 28-03-2018 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Gene3D G3DSA:3.30.70.870 306 405 4.1E-30 T 28-03-2018 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 144 3.8E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Gene3D G3DSA:3.30.70.240 406 487 6.4E-20 T 28-03-2018 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 606 2.3E-285 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 SUPERFAMILY SSF54980 306 392 3.31E-12 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 SUPERFAMILY SSF54980 403 519 3.64E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 PRINTS PR00315 GTP-binding elongation factor signature 74 84 3.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 PRINTS PR00315 GTP-binding elongation factor signature 10 23 3.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 PRINTS PR00315 GTP-binding elongation factor signature 90 101 3.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 PRINTS PR00315 GTP-binding elongation factor signature 126 135 3.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 PRINTS PR00315 GTP-binding elongation factor signature 54 62 3.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 SUPERFAMILY SSF52540 3 209 4.67E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Gene3D G3DSA:2.40.50.250 490 580 1.6E-39 T 28-03-2018 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Pfam PF00009 Elongation factor Tu GTP binding domain 7 198 1.8E-55 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 SUPERFAMILY SSF50447 154 303 2.83E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS05605 1e544e99d87ebb86cbd20daa083de7ed 611 Gene3D G3DSA:2.40.30.10 192 304 1.5E-21 T 28-03-2018 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 Gene3D G3DSA:1.10.10.10 6 93 4.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 Gene3D G3DSA:3.40.190.10 174 262 5.4E-24 T 28-03-2018 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 SUPERFAMILY SSF46785 4 85 1.56E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 Pfam PF03466 LysR substrate binding domain 91 292 1.4E-35 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 64 2.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 SUPERFAMILY SSF53850 93 295 1.81E-38 T 28-03-2018 hmeg3_RS23220 0b81011664e6b03b94235ad0a2178b39 301 Gene3D G3DSA:3.40.190.10 94 173 3.1E-9 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 SUPERFAMILY SSF50939 1203 1360 1.43E-5 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 SUPERFAMILY SSF49313 1588 1677 4.24E-17 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.1310 599 687 8.9E-5 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.1310 793 899 4.3E-19 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.1310 688 792 1.0E-5 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.1310 1344 1447 1.8E-4 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.1310 1252 1343 7.3E-7 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.10 1189 1251 8.8E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.10 534 598 0.099 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.650 411 520 4.9E-8 T 28-03-2018 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Pfam PF14252 Domain of unknown function (DUF4347) 84 242 2.3E-50 T 28-03-2018 IPR025592 Domain of unknown function DUF4347 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Gene3D G3DSA:2.60.40.10 1583 1680 5.6E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 SMART SM00736 1585 1685 2.0E-11 T 28-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Pfam PF12245 Bacterial Ig-like domain (group 3) 591 609 3.6 T 28-03-2018 IPR022038 Bacterial Ig-like domain hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Pfam PF12245 Bacterial Ig-like domain (group 3) 695 713 0.21 T 28-03-2018 IPR022038 Bacterial Ig-like domain hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Pfam PF12245 Bacterial Ig-like domain (group 3) 799 818 1.1 T 28-03-2018 IPR022038 Bacterial Ig-like domain hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Pfam PF12245 Bacterial Ig-like domain (group 3) 1246 1260 4.3 T 28-03-2018 IPR022038 Bacterial Ig-like domain hmeg3_RS11760 a1754e28eea4a620e268e073ced1fbb5 1737 Pfam PF12245 Bacterial Ig-like domain (group 3) 1350 1368 3.1 T 28-03-2018 IPR022038 Bacterial Ig-like domain hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 SUPERFAMILY SSF46785 3 86 4.58E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 SUPERFAMILY SSF53850 94 296 1.1E-32 T 28-03-2018 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 Gene3D G3DSA:3.40.190.10 178 264 9.8E-17 T 28-03-2018 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 Gene3D G3DSA:3.40.190.10 90 177 1.5E-17 T 28-03-2018 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 Gene3D G3DSA:1.10.10.10 5 87 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 5.9E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10915 6546b435c77a6a2578df1cbe833012b9 306 Pfam PF03466 LysR substrate binding domain 92 293 2.8E-31 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS07085 981b4805a56a03fe6b7f591087002bd3 337 Pfam PF09084 NMT1/THI5 like 49 260 1.0E-21 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS07085 981b4805a56a03fe6b7f591087002bd3 337 Gene3D G3DSA:3.40.190.10 134 313 6.5E-23 T 28-03-2018 hmeg3_RS07085 981b4805a56a03fe6b7f591087002bd3 337 Gene3D G3DSA:3.40.190.10 28 133 3.1E-13 T 28-03-2018 hmeg3_RS07085 981b4805a56a03fe6b7f591087002bd3 337 SMART SM00062 31 277 0.0058 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS07085 981b4805a56a03fe6b7f591087002bd3 337 SUPERFAMILY SSF53850 31 279 6.35E-38 T 28-03-2018 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 SUPERFAMILY SSF56176 184 364 3.02E-51 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 SUPERFAMILY SSF54292 4 89 7.35E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Gene3D G3DSA:3.30.43.10 196 248 5.0E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Pfam PF01799 [2Fe-2S] binding domain 84 161 1.3E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 199 363 5.7E-46 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 70 6.2E-5 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 PIRSF PIRSF036557 2 485 1.6E-215 T 28-03-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Gene3D G3DSA:3.30.390.50 366 482 1.3E-30 T 28-03-2018 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 SUPERFAMILY SSF55447 370 475 4.58E-34 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 5 472 1.6E-206 T 28-03-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Gene3D G3DSA:3.30.465.10 249 364 1.6E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Gene3D G3DSA:3.10.20.30 2 84 1.1E-26 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Gene3D G3DSA:1.10.150.120 85 195 9.3E-35 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 SMART SM01092 371 472 3.9E-38 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 372 471 1.9E-31 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal hmeg3_RS17075 4540b26c443e7703fb4ef5be2a5b48a1 504 SUPERFAMILY SSF47741 96 209 1.7E-32 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS22725 537ed8b82869a9efcc0dfeec5b55a8b7 129 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 6.5E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22725 537ed8b82869a9efcc0dfeec5b55a8b7 129 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.798 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22725 537ed8b82869a9efcc0dfeec5b55a8b7 129 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22725 537ed8b82869a9efcc0dfeec5b55a8b7 129 SUPERFAMILY SSF64263 1 119 4.97E-50 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22725 537ed8b82869a9efcc0dfeec5b55a8b7 129 Gene3D G3DSA:3.90.1030.10 1 117 1.9E-48 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22725 537ed8b82869a9efcc0dfeec5b55a8b7 129 Pfam PF01196 Ribosomal protein L17 20 116 4.8E-34 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 Hamap MF_00105 Transcription elongation factor GreA [greA]. 26 179 27.451 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 SUPERFAMILY SSF54534 106 180 3.27E-20 T 28-03-2018 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 Gene3D G3DSA:1.10.287.180 27 99 1.8E-27 T 28-03-2018 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 PIRSF PIRSF006092 25 182 3.0E-44 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 Pfam PF03449 Transcription elongation factor, N-terminal 28 98 2.6E-24 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 107 180 6.9E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 Hamap MF_00930 Transcription elongation factor GreB [greB]. 25 181 51.042 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 Gene3D G3DSA:3.10.50.30 103 185 5.3E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 27 181 6.8E-66 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 41 72 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 hmeg3_RS13300 912e0ca8b77167da100f135db948a9f2 185 SUPERFAMILY SSF46557 27 101 1.26E-26 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SUPERFAMILY SSF52172 701 820 1.85E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Gene3D G3DSA:3.30.565.10 387 550 1.5E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Gene3D G3DSA:1.10.287.130 308 379 1.1E-17 T 28-03-2018 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SUPERFAMILY SSF47226 798 811 1.57E-18 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SUPERFAMILY SSF47226 845 943 1.57E-18 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Gene3D G3DSA:3.40.50.2300 687 827 1.1E-43 T 28-03-2018 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Pfam PF00072 Response regulator receiver domain 702 814 5.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SMART SM00387 430 546 4.0E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Gene3D G3DSA:3.40.50.2300 554 673 7.1E-4 T 28-03-2018 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Gene3D G3DSA:1.20.120.160 842 956 1.1E-12 T 28-03-2018 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 1.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 1.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 1.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 1.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SMART SM00388 318 383 8.9E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SMART SM00448 700 815 2.5E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SUPERFAMILY SSF47384 305 384 1.06E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Pfam PF00512 His Kinase A (phospho-acceptor) domain 318 383 5.5E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 SUPERFAMILY SSF55874 372 544 2.1E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11545 f108f597a155759c2894e1838a1480df 956 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 430 545 3.9E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07435 9b469a6dd86c56c3311f738def41f134 146 SUPERFAMILY SSF46785 5 102 4.88E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07435 9b469a6dd86c56c3311f738def41f134 146 Gene3D G3DSA:1.10.10.10 2 144 7.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07435 9b469a6dd86c56c3311f738def41f134 146 Pfam PF01638 HxlR-like helix-turn-helix 16 99 2.8E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS20905 7bc2bc9e555c3241f17d9ab307b0626a 287 Pfam PF00005 ABC transporter 58 195 4.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS20905 7bc2bc9e555c3241f17d9ab307b0626a 287 Gene3D G3DSA:3.40.50.300 32 252 2.3E-59 T 28-03-2018 hmeg3_RS20905 7bc2bc9e555c3241f17d9ab307b0626a 287 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS20905 7bc2bc9e555c3241f17d9ab307b0626a 287 SMART SM00382 65 255 2.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS20905 7bc2bc9e555c3241f17d9ab307b0626a 287 SUPERFAMILY SSF52540 36 250 8.14E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 SUPERFAMILY SSF53850 89 297 3.62E-49 T 28-03-2018 hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 Gene3D G3DSA:1.10.10.10 2 84 7.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 Pfam PF03466 LysR substrate binding domain 89 291 1.0E-44 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 Gene3D G3DSA:3.40.190.10 92 176 2.6E-17 T 28-03-2018 hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 SUPERFAMILY SSF46785 4 83 1.14E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 Gene3D G3DSA:3.40.190.10 177 263 6.5E-28 T 28-03-2018 hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.0E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.0E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20525 6a88402ce71b5155824388b6b06d4522 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.0E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 Gene3D G3DSA:3.40.50.620 1 182 1.4E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 SMART SM00893 3 181 5.0E-55 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 PIRSF PIRSF000089 1 309 3.2E-108 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 271 8.1E-37 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 Gene3D G3DSA:3.40.50.1220 184 309 5.6E-62 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 Pfam PF01012 Electron transfer flavoprotein domain 4 168 2.4E-37 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 252 278 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 SUPERFAMILY SSF52402 3 183 1.95E-55 T 28-03-2018 hmeg3_RS16055 6e8f61318427c4d4770c6266b7e75d84 309 SUPERFAMILY SSF52467 188 308 5.54E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS22200 73e92c63445d17c9a48d016c8ba59254 432 Pfam PF07690 Major Facilitator Superfamily 62 389 8.3E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS22200 73e92c63445d17c9a48d016c8ba59254 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS22200 73e92c63445d17c9a48d016c8ba59254 432 Gene3D G3DSA:1.20.1250.20 6 228 1.2E-22 T 28-03-2018 hmeg3_RS22200 73e92c63445d17c9a48d016c8ba59254 432 Gene3D G3DSA:1.20.1250.20 235 431 1.9E-23 T 28-03-2018 hmeg3_RS22200 73e92c63445d17c9a48d016c8ba59254 432 SUPERFAMILY SSF103473 10 428 1.28E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 SUPERFAMILY SSF53850 91 296 5.83E-47 T 28-03-2018 hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 Pfam PF03466 LysR substrate binding domain 90 292 1.0E-43 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 Gene3D G3DSA:3.40.190.10 176 264 6.4E-28 T 28-03-2018 hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 SUPERFAMILY SSF46785 4 85 5.99E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 Gene3D G3DSA:1.10.10.10 3 84 6.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.8E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17060 c67f146d4897c221989e639c0edec831 302 Gene3D G3DSA:3.40.190.10 89 175 7.8E-13 T 28-03-2018 hmeg3_RS06595 47e5e2ba10cbdb8f5be3858f89aa11b7 279 SUPERFAMILY SSF48452 14 33 3.08E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS06595 47e5e2ba10cbdb8f5be3858f89aa11b7 279 SUPERFAMILY SSF48452 168 258 3.08E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS06595 47e5e2ba10cbdb8f5be3858f89aa11b7 279 Pfam PF13371 Tetratricopeptide repeat 197 268 4.0E-20 T 28-03-2018 hmeg3_RS06595 47e5e2ba10cbdb8f5be3858f89aa11b7 279 Pfam PF13369 Transglutaminase-like superfamily 41 195 1.4E-47 T 28-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 hmeg3_RS06595 47e5e2ba10cbdb8f5be3858f89aa11b7 279 Gene3D G3DSA:1.25.40.10 10 277 1.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS14550 1feff630dc333bb7387ac12646699a19 281 Pfam PF01522 Polysaccharide deacetylase 41 189 4.5E-19 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 hmeg3_RS14550 1feff630dc333bb7387ac12646699a19 281 SUPERFAMILY SSF88713 39 267 5.0E-38 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS14550 1feff630dc333bb7387ac12646699a19 281 Gene3D G3DSA:3.20.20.370 39 274 9.9E-35 T 28-03-2018 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 90 134 1.0E-8 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 SUPERFAMILY SSF51344 4 87 1.44E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 Gene3D G3DSA:2.60.15.10 1 91 7.7E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 85 2.6E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 SUPERFAMILY SSF46604 89 137 3.66E-12 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 132 21.371 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 134 3.6E-42 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 88 1.0E-29 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02450 94c4dcf86aaaea3ea00ecaae0f9e85cb 140 Gene3D G3DSA:1.20.5.440 92 137 1.2E-7 T 28-03-2018 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 390 44.48 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 SUPERFAMILY SSF54675 1 137 2.59E-44 T 28-03-2018 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 SUPERFAMILY SSF51690 118 388 4.32E-88 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 PIRSF PIRSF000484 1 380 1.7E-65 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 164 389 3.6E-74 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 Gene3D G3DSA:3.20.140.10 1 390 1.5E-100 T 28-03-2018 hmeg3_RS14580 63f3a2334c0187634232ba9003d4af32 390 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 389 2.0E-143 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 hmeg3_RS16080 4275df512499d7ee63517225f923f0ad 244 Gene3D G3DSA:3.40.50.300 1 243 6.6E-75 T 28-03-2018 hmeg3_RS16080 4275df512499d7ee63517225f923f0ad 244 PIRSF PIRSF039085 1 242 2.1E-106 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS16080 4275df512499d7ee63517225f923f0ad 244 SUPERFAMILY SSF52540 3 237 1.13E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16080 4275df512499d7ee63517225f923f0ad 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16080 4275df512499d7ee63517225f923f0ad 244 Pfam PF00005 ABC transporter 19 167 3.9E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16080 4275df512499d7ee63517225f923f0ad 244 SMART SM00382 28 215 3.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS18880 d75d51a708ab7dd682f73d6533a9e3d6 408 Gene3D G3DSA:1.20.1250.20 198 408 1.6E-16 T 28-03-2018 hmeg3_RS18880 d75d51a708ab7dd682f73d6533a9e3d6 408 Gene3D G3DSA:1.20.1250.20 6 189 4.9E-17 T 28-03-2018 hmeg3_RS18880 d75d51a708ab7dd682f73d6533a9e3d6 408 Pfam PF07690 Major Facilitator Superfamily 24 353 6.0E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18880 d75d51a708ab7dd682f73d6533a9e3d6 408 SUPERFAMILY SSF103473 10 400 1.31E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 SUPERFAMILY SSF55136 145 296 2.49E-27 T 28-03-2018 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 Pfam PF06445 GyrI-like small molecule binding domain 145 296 1.2E-28 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 SMART SM00342 31 114 1.4E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 Gene3D G3DSA:3.20.80.10 210 297 2.9E-10 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 SMART SM00871 144 297 1.3E-30 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 SUPERFAMILY SSF46689 15 65 3.18E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 Gene3D G3DSA:1.10.10.60 5 67 5.3E-11 T 28-03-2018 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 SUPERFAMILY SSF46689 67 124 1.21E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 Gene3D G3DSA:1.10.10.60 68 120 2.5E-12 T 28-03-2018 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 Pfam PF12833 Helix-turn-helix domain 39 115 2.9E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 Gene3D G3DSA:3.20.80.10 121 209 3.2E-13 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain hmeg3_RS10820 a128f894d3df38f6c0ee45aba4683e2f 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 68 110 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS05330 a1f7de3a69d2889fbc8f13204f5f3757 88 Pfam PF07235 Protein of unknown function (DUF1427) 2 83 4.6E-34 T 28-03-2018 IPR009872 Protein of unknown function DUF1427 hmeg3_RS05330 a1f7de3a69d2889fbc8f13204f5f3757 88 TIGRFAM TIGR03510 XapX: XapX domain 3 50 1.6E-18 T 28-03-2018 IPR020017 XapX domain hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 Gene3D G3DSA:1.10.10.10 1 89 1.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 SUPERFAMILY SSF46785 3 112 4.46E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 Gene3D G3DSA:3.40.190.10 177 261 3.9E-15 T 28-03-2018 hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 SUPERFAMILY SSF53850 91 296 6.7E-34 T 28-03-2018 hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 Gene3D G3DSA:3.40.190.10 93 176 2.3E-12 T 28-03-2018 hmeg3_RS12545 ea6dcf3d91d1973130c38366b9f2fb4e 298 Pfam PF03466 LysR substrate binding domain 90 295 2.4E-30 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 Pfam PF01494 FAD binding domain 8 322 1.8E-19 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 SUPERFAMILY SSF51905 284 397 3.59E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 SUPERFAMILY SSF51905 7 182 3.59E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.6E-19 T 28-03-2018 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 1.6E-19 T 28-03-2018 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 1.6E-19 T 28-03-2018 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.6E-19 T 28-03-2018 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 397 5.0E-111 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 hmeg3_RS03140 d8b87d4f21ff039631802a628256eb31 400 Gene3D G3DSA:3.50.50.60 1 324 4.3E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 Gene3D G3DSA:3.40.190.10 30 185 3.0E-39 T 28-03-2018 hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 SMART SM00079 40 263 2.5E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 Gene3D G3DSA:3.40.190.10 186 265 1.2E-14 T 28-03-2018 hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 SMART SM00062 40 264 2.6E-65 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 262 1.1E-66 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS02665 c7c6aad5feb292e813be6cc0085b1164 265 SUPERFAMILY SSF53850 6 263 2.04E-68 T 28-03-2018 hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 SUPERFAMILY SSF51735 1 130 1.97E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 Gene3D G3DSA:3.40.50.720 1 177 2.0E-26 T 28-03-2018 hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 Gene3D G3DSA:1.10.1040.10 178 309 1.6E-26 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 179 302 6.4E-21 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 4 304 1.9E-58 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 SUPERFAMILY SSF48179 179 303 1.43E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS00915 7e36e15afcb9e16b82259ffc8eb28157 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 151 1.3E-35 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 SUPERFAMILY SSF75217 85 243 1.57E-48 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 Pfam PF00588 SpoU rRNA Methylase family 96 236 3.2E-38 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 SUPERFAMILY SSF55315 3 76 1.88E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 SMART SM00967 5 81 7.5E-17 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 Gene3D G3DSA:3.40.1280.10 79 245 5.4E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 242 2.8E-71 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 Gene3D G3DSA:3.30.1330.30 1 76 5.9E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 77 4.1E-17 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 hmeg3_RS08970 a55e50b11e3faaac8698954d5b6b1867 245 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 243 43.757 T 28-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 SUPERFAMILY SSF55120 7 270 9.06E-88 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 Pfam PF01416 tRNA pseudouridine synthase 162 264 4.8E-32 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 Pfam PF01416 tRNA pseudouridine synthase 15 100 2.6E-5 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 8 263 35.361 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 Gene3D G3DSA:3.30.70.660 125 262 1.7E-40 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 9 258 4.4E-64 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 Gene3D G3DSA:3.30.70.580 5 124 1.5E-29 T 28-03-2018 hmeg3_RS17225 609d0316e26b8674c1bbf42389a64d2c 279 PIRSF PIRSF001430 7 276 3.2E-73 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 Gene3D G3DSA:3.40.190.10 27 121 3.3E-5 T 28-03-2018 hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 Gene3D G3DSA:3.40.190.10 122 261 2.9E-34 T 28-03-2018 hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 SMART SM00062 28 257 0.01 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 247 3.9E-81 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 1 280 1.8E-81 T 28-03-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 SUPERFAMILY SSF53850 50 239 2.79E-49 T 28-03-2018 hmeg3_RS12320 412c8bde664f4adcf8e49bf141ca5bdb 288 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 31 270 8.7E-72 T 28-03-2018 hmeg3_RS01770 da0a1afdad0896effdc5e2a3d12711b7 209 SMART SM00947 27 193 9.7E-68 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS01770 da0a1afdad0896effdc5e2a3d12711b7 209 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS01770 da0a1afdad0896effdc5e2a3d12711b7 209 SUPERFAMILY SSF53056 2 198 5.36E-64 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS01770 da0a1afdad0896effdc5e2a3d12711b7 209 Gene3D G3DSA:3.40.1050.10 1 209 5.5E-66 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS01770 da0a1afdad0896effdc5e2a3d12711b7 209 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS01770 da0a1afdad0896effdc5e2a3d12711b7 209 Pfam PF00484 Carbonic anhydrase 34 188 1.2E-49 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 318 1.5E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 Pfam PF00005 ABC transporter 33 196 6.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 SUPERFAMILY SSF52540 12 267 7.06E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 SMART SM00382 41 246 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 Gene3D G3DSA:3.40.50.300 9 341 3.2E-74 T 28-03-2018 hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 337 1.7E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS14170 5292fa4081c0bc76d9ecdac0ff124ab6 342 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 SUPERFAMILY SSF53850 90 296 3.62E-46 T 28-03-2018 hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.4E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 Gene3D G3DSA:3.40.190.10 175 264 2.7E-26 T 28-03-2018 hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 Pfam PF03466 LysR substrate binding domain 89 293 3.6E-45 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 Gene3D G3DSA:3.40.190.10 89 174 2.4E-12 T 28-03-2018 hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 SUPERFAMILY SSF46785 4 111 5.53E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13595 7c1473df93df451cef7478dfcd189203 304 Gene3D G3DSA:1.10.10.10 3 84 4.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17335 6b86408c543fc5e702d5451cf666e9b3 539 SUPERFAMILY SSF161098 3 248 7.98E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17335 6b86408c543fc5e702d5451cf666e9b3 539 SUPERFAMILY SSF161098 283 534 7.33E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17335 6b86408c543fc5e702d5451cf666e9b3 539 Gene3D G3DSA:1.10.3720.10 318 539 6.0E-20 T 28-03-2018 hmeg3_RS17335 6b86408c543fc5e702d5451cf666e9b3 539 Gene3D G3DSA:1.10.3720.10 33 254 2.4E-22 T 28-03-2018 hmeg3_RS17335 6b86408c543fc5e702d5451cf666e9b3 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 254 2.7E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17335 6b86408c543fc5e702d5451cf666e9b3 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 536 3.6E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21340 d9b6a30d4b833a728d282fad378b8f24 493 SUPERFAMILY SSF54637 23 114 9.12E-10 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS21340 d9b6a30d4b833a728d282fad378b8f24 493 Pfam PF01575 MaoC like domain 29 106 1.1E-6 T 28-03-2018 IPR002539 MaoC-like domain hmeg3_RS21340 d9b6a30d4b833a728d282fad378b8f24 493 SUPERFAMILY SSF51735 293 470 2.06E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21340 d9b6a30d4b833a728d282fad378b8f24 493 Gene3D G3DSA:3.10.129.10 12 130 1.2E-9 T 28-03-2018 hmeg3_RS21340 d9b6a30d4b833a728d282fad378b8f24 493 Gene3D G3DSA:3.40.50.720 292 484 2.7E-11 T 28-03-2018 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 SUPERFAMILY SSF46600 212 263 7.85E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Gene3D G3DSA:4.10.860.10 202 264 2.7E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 SUPERFAMILY SSF82771 38 121 8.76E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 30 613 8.8E-174 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 SMART SM00278 580 599 0.98 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 SMART SM00278 612 631 340.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Pfam PF02151 UvrB/uvrC motif 225 257 1.6E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Pfam PF14520 Helix-hairpin-helix domain 582 632 8.4E-7 T 28-03-2018 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 419 566 3.7E-47 T 28-03-2018 IPR001162 UvrC family homology region hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 SMART SM00465 38 119 2.3E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Pfam PF01541 GIY-YIG catalytic domain 40 113 3.8E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Hamap MF_00203 UvrABC system protein C [uvrC]. 25 631 26.574 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Gene3D G3DSA:1.10.150.20 578 633 1.1E-12 T 28-03-2018 hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 SUPERFAMILY SSF47781 532 633 2.86E-20 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS16645 5643ce2dfa83eaa849a2608186ca6725 633 Gene3D G3DSA:3.40.1440.10 25 122 1.2E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 SUPERFAMILY SSF55073 241 415 6.91E-42 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 414 1.0E-31 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 SUPERFAMILY SSF141868 430 677 1.96E-92 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 SMART SM00267 225 414 1.4E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 SMART SM00052 424 672 5.1E-124 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 Pfam PF13185 GAF domain 72 215 9.4E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 409 9.9E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 Gene3D G3DSA:3.30.450.40 34 246 1.4E-17 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 Pfam PF00563 EAL domain 430 666 7.0E-77 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 Gene3D G3DSA:3.20.20.450 423 685 4.9E-108 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 Gene3D G3DSA:3.30.70.270 247 422 1.2E-55 T 28-03-2018 hmeg3_RS00785 d02a8cf141f9ca6050fee77e85da5f61 696 SUPERFAMILY SSF55781 50 212 1.77E-10 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS23425 d1b02d85edbf76ec714e3e8c8145a2f8 263 Gene3D G3DSA:3.40.50.300 10 263 1.7E-72 T 28-03-2018 hmeg3_RS23425 d1b02d85edbf76ec714e3e8c8145a2f8 263 PIRSF PIRSF039085 10 263 4.4E-116 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS23425 d1b02d85edbf76ec714e3e8c8145a2f8 263 Pfam PF00005 ABC transporter 29 187 4.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23425 d1b02d85edbf76ec714e3e8c8145a2f8 263 SUPERFAMILY SSF52540 13 257 9.41E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23425 d1b02d85edbf76ec714e3e8c8145a2f8 263 SMART SM00382 38 235 2.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23425 d1b02d85edbf76ec714e3e8c8145a2f8 263 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11740 c4369e3f1c486597cdeb67ad79511fe8 257 SUPERFAMILY SSF56214 45 125 4.01E-11 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS11740 c4369e3f1c486597cdeb67ad79511fe8 257 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 134 197 2.5E-11 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS11740 c4369e3f1c486597cdeb67ad79511fe8 257 Gene3D G3DSA:3.90.470.20 36 142 7.7E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS11740 c4369e3f1c486597cdeb67ad79511fe8 257 Gene3D G3DSA:3.90.470.20 143 250 1.1E-10 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS11740 c4369e3f1c486597cdeb67ad79511fe8 257 SUPERFAMILY SSF56214 133 252 1.57E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 4.7E-37 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 SMART SM01387 8 88 4.5E-51 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 SUPERFAMILY SSF47060 3 89 2.06E-34 T 28-03-2018 IPR009068 S15/NS1, RNA-binding hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 Gene3D G3DSA:1.10.287.10 2 89 4.0E-34 T 28-03-2018 hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 3.0E-31 T 28-03-2018 hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 Pfam PF00312 Ribosomal protein S15 8 88 3.2E-36 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS13860 226445d9da01e4c75185b8495fb507ca 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 89 21.725 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS09635 738f19ac34af0cc76a44ea15dd94a47c 206 SUPERFAMILY SSF52141 48 193 8.5E-11 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS09635 738f19ac34af0cc76a44ea15dd94a47c 206 Pfam PF03167 Uracil DNA glycosylase superfamily 55 190 7.4E-10 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS09635 738f19ac34af0cc76a44ea15dd94a47c 206 Gene3D G3DSA:3.40.470.10 13 206 1.0E-16 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS24295 318a4997a5fcdcac7495f1a9a3e8bfe7 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 143 2.1E-28 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 hmeg3_RS24295 318a4997a5fcdcac7495f1a9a3e8bfe7 148 Gene3D G3DSA:3.30.530.20 2 148 1.2E-30 T 28-03-2018 IPR023393 START-like domain hmeg3_RS24295 318a4997a5fcdcac7495f1a9a3e8bfe7 148 SUPERFAMILY SSF55961 3 144 3.02E-41 T 28-03-2018 hmeg3_RS05840 2c1dba0926329afd94faa4557c217ef2 410 Pfam PF07690 Major Facilitator Superfamily 24 366 2.3E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS05840 2c1dba0926329afd94faa4557c217ef2 410 Gene3D G3DSA:1.20.1250.20 17 200 3.6E-23 T 28-03-2018 hmeg3_RS05840 2c1dba0926329afd94faa4557c217ef2 410 Gene3D G3DSA:1.20.1250.20 204 408 1.5E-14 T 28-03-2018 hmeg3_RS05840 2c1dba0926329afd94faa4557c217ef2 410 SUPERFAMILY SSF103473 11 405 1.44E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS06080 87e32537eb117159c1da286ab43ae02a 269 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 44 269 2.2E-61 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 hmeg3_RS06080 87e32537eb117159c1da286ab43ae02a 269 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 28 269 2.9E-52 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 Gene3D G3DSA:3.40.630.10 270 417 1.2E-20 T 28-03-2018 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 Gene3D G3DSA:3.40.630.10 6 269 7.3E-32 T 28-03-2018 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 25 411 1.4E-103 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 SUPERFAMILY SSF53187 342 415 2.31E-69 T 28-03-2018 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 SUPERFAMILY SSF53187 14 230 2.31E-69 T 28-03-2018 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 Pfam PF01546 Peptidase family M20/M25/M40 85 414 7.2E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 SUPERFAMILY SSF55031 220 330 4.88E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS11180 9f2f1477f6999ad1cfc999575002cbb0 417 PIRSF PIRSF001235 9 417 6.1E-116 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 Pfam PF03466 LysR substrate binding domain 92 289 1.5E-21 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS11075 e4295175e688a3834722237814635a62 309 Gene3D G3DSA:1.10.10.10 1 83 1.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11075 e4295175e688a3834722237814635a62 309 SUPERFAMILY SSF46785 1 79 2.01E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11075 e4295175e688a3834722237814635a62 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 4.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 SUPERFAMILY SSF53850 92 294 2.53E-23 T 28-03-2018 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 Gene3D G3DSA:3.40.190.10 89 175 2.6E-11 T 28-03-2018 hmeg3_RS11075 e4295175e688a3834722237814635a62 309 Gene3D G3DSA:3.40.190.10 176 261 1.5E-14 T 28-03-2018 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 Gene3D G3DSA:3.40.190.10 181 271 6.8E-18 T 28-03-2018 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 SUPERFAMILY SSF46785 3 86 3.78E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 Gene3D G3DSA:1.10.10.10 2 92 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 SUPERFAMILY SSF53850 89 298 2.17E-27 T 28-03-2018 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 Gene3D G3DSA:3.40.190.10 93 180 7.1E-16 T 28-03-2018 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 Pfam PF03466 LysR substrate binding domain 89 292 1.8E-30 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04785 41bb325fc6da0c4cd0686ea16fb48311 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02065 ef2b0ba4b7df3605f2cd2a9477e21f99 218 PRINTS PR01021 OMPA domain signature 112 134 3.2E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS02065 ef2b0ba4b7df3605f2cd2a9477e21f99 218 PRINTS PR01021 OMPA domain signature 157 173 3.2E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS02065 ef2b0ba4b7df3605f2cd2a9477e21f99 218 PRINTS PR01021 OMPA domain signature 142 157 3.2E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS02065 ef2b0ba4b7df3605f2cd2a9477e21f99 218 SUPERFAMILY SSF103088 99 212 3.92E-36 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS02065 ef2b0ba4b7df3605f2cd2a9477e21f99 218 Gene3D G3DSA:3.30.1330.60 78 218 8.3E-42 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS02065 ef2b0ba4b7df3605f2cd2a9477e21f99 218 Pfam PF00691 OmpA family 112 206 2.1E-20 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 Pfam PF00005 ABC transporter 31 182 7.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 Pfam PF00005 ABC transporter 283 437 7.1E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 Gene3D G3DSA:3.40.50.300 1 241 4.6E-50 T 28-03-2018 hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 SMART SM00382 291 486 9.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 SMART SM00382 40 230 8.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 SUPERFAMILY SSF52540 15 239 2.17E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 SUPERFAMILY SSF52540 271 497 1.4E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS21060 c2df96c01eac204acb6354b52e568e92 519 Gene3D G3DSA:3.40.50.300 267 517 4.8E-38 T 28-03-2018 hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 Pfam PF13410 Glutathione S-transferase, C-terminal domain 142 181 1.2E-8 T 28-03-2018 hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 Gene3D G3DSA:3.40.30.10 1 94 1.3E-25 T 28-03-2018 hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 Gene3D G3DSA:1.20.1050.10 95 216 2.9E-25 T 28-03-2018 hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 83 4.2E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 SUPERFAMILY SSF47616 85 214 1.71E-31 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 SUPERFAMILY SSF52833 2 88 3.12E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS18525 7eed24789dd35aade18082ac243a54b9 216 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 5 215 1.5E-91 T 28-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 Gene3D G3DSA:1.10.443.10 118 314 4.1E-37 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 Pfam PF00589 Phage integrase family 119 306 3.4E-34 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 SUPERFAMILY SSF56349 14 312 3.24E-42 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 92 1.2E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 15 322 1.1E-101 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 Gene3D G3DSA:1.10.150.130 10 117 8.0E-23 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS02840 02972227c7db02fd39053704e7698545 326 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 320 54.935 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD hmeg3_RS04120 40ad6390b5b742d9b6b552fe10045a1e 210 SUPERFAMILY SSF47616 77 203 1.09E-30 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS04120 40ad6390b5b742d9b6b552fe10045a1e 210 SUPERFAMILY SSF52833 2 85 3.1E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS04120 40ad6390b5b742d9b6b552fe10045a1e 210 Pfam PF00043 Glutathione S-transferase, C-terminal domain 134 196 1.2E-11 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS04120 40ad6390b5b742d9b6b552fe10045a1e 210 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 80 5.7E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS04120 40ad6390b5b742d9b6b552fe10045a1e 210 Gene3D G3DSA:3.40.30.10 1 100 2.3E-27 T 28-03-2018 hmeg3_RS04120 40ad6390b5b742d9b6b552fe10045a1e 210 Gene3D G3DSA:1.20.1050.10 101 209 1.4E-24 T 28-03-2018 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Gene3D G3DSA:3.30.300.30 529 644 9.1E-27 T 28-03-2018 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Pfam PF00501 AMP-binding enzyme 95 535 5.9E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Gene3D G3DSA:3.40.50.980 80 272 1.4E-48 T 28-03-2018 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 658 1.5E-298 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Gene3D G3DSA:3.40.50.980 273 441 8.7E-39 T 28-03-2018 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 87 7.8E-21 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 9 660 51.88 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Gene3D G3DSA:2.30.38.10 442 528 1.6E-10 T 28-03-2018 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 SUPERFAMILY SSF56801 15 655 1.83E-173 T 28-03-2018 hmeg3_RS15885 edc0d49d49108952eaccc0d6f6d53902 660 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 625 4.6E-28 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82693 575 667 2.01E-8 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Gene3D G3DSA:3.30.70.1430 42 134 3.2E-24 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1046 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Gene3D G3DSA:3.30.70.1430 568 670 1.6E-15 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.1E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 1.1E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.1E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.1E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.1E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Gene3D G3DSA:3.30.2090.10 190 277 3.5E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Gene3D G3DSA:3.30.2090.10 725 819 6.0E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82866 299 506 8.89E-35 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82714 193 275 4.32E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Pfam PF00873 AcrB/AcrD/AcrF family 5 1037 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Gene3D G3DSA:1.20.1640.10 293 519 8.9E-36 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82693 155 191 2.09E-20 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82693 277 333 2.09E-20 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82714 726 816 2.09E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 Gene3D G3DSA:1.20.1640.10 820 1040 1.0E-40 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82693 42 127 1.07E-22 T 28-03-2018 hmeg3_RS02175 f40516c8cbbdc2dd478284945a82ee92 1065 SUPERFAMILY SSF82866 816 1036 4.71E-58 T 28-03-2018 hmeg3_RS13780 b442c961a52711f93ac8ea2e2840b44c 158 SUPERFAMILY SSF56770 9 153 2.62E-67 T 28-03-2018 hmeg3_RS13780 b442c961a52711f93ac8ea2e2840b44c 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.551 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13780 b442c961a52711f93ac8ea2e2840b44c 158 Gene3D G3DSA:3.40.50.700 10 156 6.1E-49 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13780 b442c961a52711f93ac8ea2e2840b44c 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.0E-77 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13780 b442c961a52711f93ac8ea2e2840b44c 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 3.8E-22 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13780 b442c961a52711f93ac8ea2e2840b44c 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 SUPERFAMILY SSF56601 1 280 3.6E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 259 1.8E-68 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 SMART SM00936 280 370 2.6E-31 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 Gene3D G3DSA:3.40.710.10 3 297 2.9E-54 T 28-03-2018 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 3.1E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 132 3.1E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 3.1E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 Gene3D G3DSA:2.60.410.10 298 369 1.0E-21 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 280 368 3.3E-24 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS02780 9e439cafe47976f58cc517685469fc8a 386 SUPERFAMILY SSF69189 280 372 4.9E-25 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS18710 fd128fa2a0214f4846fa5fa0fdbcbca2 150 SMART SM00347 34 137 2.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS18710 fd128fa2a0214f4846fa5fa0fdbcbca2 150 Pfam PF01047 MarR family 41 101 6.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS18710 fd128fa2a0214f4846fa5fa0fdbcbca2 150 Gene3D G3DSA:1.10.10.10 2 149 6.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18710 fd128fa2a0214f4846fa5fa0fdbcbca2 150 SUPERFAMILY SSF46785 14 148 4.69E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08200 853cbd83f84be44385e92a35ae13f8e5 238 Gene3D G3DSA:2.60.40.10 107 231 0.0011 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS08200 853cbd83f84be44385e92a35ae13f8e5 238 Pfam PF13861 FlgD Tudor-like domain 89 234 1.9E-18 T 28-03-2018 IPR025963 FlgD Tudor-like domain hmeg3_RS08200 853cbd83f84be44385e92a35ae13f8e5 238 Pfam PF13860 FlgD Ig-like domain 122 195 8.0E-23 T 28-03-2018 IPR025965 FlgD Ig-like domain hmeg3_RS08200 853cbd83f84be44385e92a35ae13f8e5 238 Pfam PF03963 Flagellar hook capping protein - N-terminal region 15 79 1.3E-21 T 28-03-2018 IPR005648 Flagellar hook capping protein hmeg3_RS18850 e4d33bbf7909cd9c3c81ac65e01cca1f 175 SMART SM00986 9 167 1.9E-6 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS18850 e4d33bbf7909cd9c3c81ac65e01cca1f 175 SMART SM00987 9 167 1.9E-6 T 28-03-2018 hmeg3_RS18850 e4d33bbf7909cd9c3c81ac65e01cca1f 175 Gene3D G3DSA:3.40.470.10 2 174 1.4E-47 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS18850 e4d33bbf7909cd9c3c81ac65e01cca1f 175 Pfam PF03167 Uracil DNA glycosylase superfamily 10 166 3.8E-23 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS18850 e4d33bbf7909cd9c3c81ac65e01cca1f 175 SUPERFAMILY SSF52141 8 167 3.6E-42 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 169 5.2E-63 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 169 33.467 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 Gene3D G3DSA:3.30.160.20 16 78 1.9E-22 T 28-03-2018 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 ProSitePatterns PS00585 Ribosomal protein S5 signature. 34 66 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 80 2.2E-24 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 SUPERFAMILY SSF54211 85 165 1.26E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 SUPERFAMILY SSF54768 15 82 4.71E-21 T 28-03-2018 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 Pfam PF03719 Ribosomal protein S5, C-terminal domain 92 163 7.0E-30 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22775 c49fbb555ac126a075bad3a8c23e3725 172 Gene3D G3DSA:3.30.230.10 82 172 1.1E-32 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 Pfam PF13458 Periplasmic binding protein 28 369 2.7E-60 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 SUPERFAMILY SSF53822 28 375 1.12E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 Gene3D G3DSA:3.40.50.2300 162 318 3.3E-28 T 28-03-2018 hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 3.7E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 338 353 3.7E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 283 296 3.7E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 3.7E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01135 8fd872a21b5f00b97283652b7bb75d0f 391 Gene3D G3DSA:3.40.50.2300 17 161 2.4E-20 T 28-03-2018 hmeg3_RS21360 11277a596502d63b08bcac23411cddfd 293 SUPERFAMILY SSF53448 7 211 9.19E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21360 11277a596502d63b08bcac23411cddfd 293 Gene3D G3DSA:3.90.550.10 2 270 1.1E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21360 11277a596502d63b08bcac23411cddfd 293 Pfam PF00535 Glycosyl transferase family 2 11 168 4.5E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS08420 ca1861669efdb9c8248501388e48f9ab 147 PIRSF PIRSF000239 1 147 1.5E-28 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS08420 ca1861669efdb9c8248501388e48f9ab 147 Pfam PF00578 AhpC/TSA family 1 124 1.8E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS08420 ca1861669efdb9c8248501388e48f9ab 147 Gene3D G3DSA:3.40.30.10 1 146 3.0E-33 T 28-03-2018 hmeg3_RS08420 ca1861669efdb9c8248501388e48f9ab 147 SUPERFAMILY SSF52833 1 146 3.17E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS15365 b3ba1bd92a19fab7b2564bdfebef4e5c 406 Pfam PF07690 Major Facilitator Superfamily 12 291 4.2E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS15365 b3ba1bd92a19fab7b2564bdfebef4e5c 406 SUPERFAMILY SSF103473 4 392 7.46E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS15365 b3ba1bd92a19fab7b2564bdfebef4e5c 406 Gene3D G3DSA:1.20.1250.20 1 185 3.1E-23 T 28-03-2018 hmeg3_RS15365 b3ba1bd92a19fab7b2564bdfebef4e5c 406 Gene3D G3DSA:1.20.1250.20 202 404 3.4E-9 T 28-03-2018 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 312 4.6E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 Pfam PF00672 HAMP domain 194 242 3.3E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 Gene3D G3DSA:1.10.287.130 237 309 2.9E-10 T 28-03-2018 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 SUPERFAMILY SSF158472 196 243 1.96E-5 T 28-03-2018 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 467 1.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 SUPERFAMILY SSF55874 303 466 2.62E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 SMART SM00387 356 468 2.4E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 SMART SM00388 247 313 1.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 Gene3D G3DSA:3.30.565.10 317 471 2.9E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 9.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 9.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 9.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 SUPERFAMILY SSF47384 231 312 3.92E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 6 465 1.5E-147 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 hmeg3_RS02205 bad043d4b9efc291edfd0e5af76d49e4 471 SMART SM00304 193 246 8.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15930 bfc45e17701e95320eb3b6a59456b977 328 SUPERFAMILY SSF144083 264 325 2.62E-16 T 28-03-2018 hmeg3_RS15930 bfc45e17701e95320eb3b6a59456b977 328 SUPERFAMILY SSF143865 5 260 2.75E-67 T 28-03-2018 hmeg3_RS15930 bfc45e17701e95320eb3b6a59456b977 328 Gene3D G3DSA:3.30.460.20 2 136 3.0E-30 T 28-03-2018 hmeg3_RS15930 bfc45e17701e95320eb3b6a59456b977 328 Pfam PF01544 CorA-like Mg2+ transporter protein 36 322 3.1E-63 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 hmeg3_RS15930 bfc45e17701e95320eb3b6a59456b977 328 Gene3D G3DSA:1.20.58.340 260 328 3.1E-17 T 28-03-2018 hmeg3_RS15930 bfc45e17701e95320eb3b6a59456b977 328 Gene3D G3DSA:1.20.58.340 137 259 2.4E-29 T 28-03-2018 hmeg3_RS24510 97e093ee342dbcdf5b8486de3eae1f1b 321 SUPERFAMILY SSF51735 107 286 2.43E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS24510 97e093ee342dbcdf5b8486de3eae1f1b 321 Gene3D G3DSA:3.40.50.720 118 287 5.8E-43 T 28-03-2018 hmeg3_RS24510 97e093ee342dbcdf5b8486de3eae1f1b 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 286 7.6E-42 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS24510 97e093ee342dbcdf5b8486de3eae1f1b 321 Gene3D G3DSA:3.40.50.720 15 117 1.5E-6 T 28-03-2018 hmeg3_RS08465 01a0ba91bbd27b581ae272c2f46fec52 409 Pfam PF00155 Aminotransferase class I and II 34 387 5.3E-55 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS08465 01a0ba91bbd27b581ae272c2f46fec52 409 Gene3D G3DSA:3.90.1150.10 281 405 6.7E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS08465 01a0ba91bbd27b581ae272c2f46fec52 409 Gene3D G3DSA:3.40.640.10 53 280 2.7E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS08465 01a0ba91bbd27b581ae272c2f46fec52 409 SUPERFAMILY SSF53383 7 390 1.2E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 SUPERFAMILY SSF52172 68 193 6.55E-21 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 Gene3D G3DSA:3.40.50.2300 68 200 4.0E-19 T 28-03-2018 hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 8 54 3.2E-14 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 SMART SM00448 72 187 2.1E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 Gene3D G3DSA:1.10.1660.10 1 60 5.5E-7 T 28-03-2018 hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 SUPERFAMILY SSF46955 8 53 3.48E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 Pfam PF12728 Helix-turn-helix domain 7 54 6.2E-12 T 28-03-2018 hmeg3_RS11535 3d0b441bbf45387b5e4da22f767afbc1 200 Pfam PF00072 Response regulator receiver domain 74 184 6.1E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 Gene3D G3DSA:3.40.50.1980 16 187 3.8E-53 T 28-03-2018 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 Gene3D G3DSA:3.40.50.1980 188 309 2.8E-39 T 28-03-2018 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 Pfam PF01297 Zinc-uptake complex component A periplasmic 30 304 1.0E-79 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 SUPERFAMILY SSF53807 24 308 1.67E-87 T 28-03-2018 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 195 212 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 27 48 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 287 305 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 244 261 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 266 284 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 137 156 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00691 Adhesin B signature 52 70 5.4E-29 T 28-03-2018 IPR006129 Adhesin B GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00690 Adhesin family signature 58 71 1.8E-28 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00690 Adhesin family signature 248 266 1.8E-28 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00690 Adhesin family signature 274 293 1.8E-28 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00690 Adhesin family signature 195 216 1.8E-28 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00690 Adhesin family signature 71 88 1.8E-28 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 hmeg3_RS07955 4d9b6bcd6b9cdbe897bfbf43ce4b5b04 311 PRINTS PR00690 Adhesin family signature 27 45 1.8E-28 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 355 1.1E-82 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 SMART SM01329 6 355 1.5E-166 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 Gene3D G3DSA:3.40.718.10 212 360 2.3E-52 T 28-03-2018 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 Gene3D G3DSA:3.40.718.10 1 211 6.1E-59 T 28-03-2018 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 358 6.5E-157 T 28-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS03740 d37a56bda152873a833db7fa262a53b8 368 SUPERFAMILY SSF53659 2 358 3.06E-111 T 28-03-2018 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Gene3D G3DSA:2.40.50.140 621 701 1.7E-23 T 28-03-2018 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.9E-13 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF03725 3' exoribonuclease family, domain 2 466 534 1.3E-5 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF54791 560 644 7.21E-22 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Gene3D G3DSA:3.30.230.70 14 233 6.1E-50 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Gene3D G3DSA:1.10.10.400 234 320 3.4E-19 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SMART SM00316 625 695 6.9E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF00013 KH domain 562 619 5.8E-10 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Gene3D G3DSA:3.30.230.70 321 549 3.8E-60 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SMART SM00322 557 622 5.1E-12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF55666 145 236 1.68E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 325 6.9E-19 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.3E-20 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 9.7E-23 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF46915 239 326 1.31E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 PIRSF PIRSF005499 1 712 1.6E-297 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF55666 455 552 1.96E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF50249 625 704 1.34E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF54211 300 493 4.1E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.456 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Pfam PF00575 S1 RNA binding domain 624 695 9.6E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 Gene3D G3DSA:3.30.1370.10 550 620 1.3E-14 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 hmeg3_RS13855 8dc28954c90a0fbc6c721d538f9811c6 712 SUPERFAMILY SSF54211 2 144 1.01E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS11210 1bb15f73cd56fae8c1a286e5fc5acf49 265 SUPERFAMILY SSF161098 60 247 2.35E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11210 1bb15f73cd56fae8c1a286e5fc5acf49 265 Gene3D G3DSA:1.10.3720.10 15 258 2.9E-25 T 28-03-2018 hmeg3_RS11210 1bb15f73cd56fae8c1a286e5fc5acf49 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 254 3.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82714 706 776 1.83E-9 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82693 558 653 1.88E-15 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 608 622 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.9E-83 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Gene3D G3DSA:3.30.2090.10 706 829 1.0E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82693 136 182 9.77E-23 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82693 268 324 9.77E-23 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Pfam PF00873 AcrB/AcrD/AcrF family 4 1049 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Gene3D G3DSA:1.20.1640.10 842 1058 8.3E-33 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Gene3D G3DSA:1.20.1640.10 281 503 5.2E-48 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Gene3D G3DSA:3.30.70.1430 40 142 1.2E-24 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82693 829 874 4.19E-5 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82693 664 704 4.19E-5 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82693 40 133 1.28E-22 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82866 290 490 1.22E-47 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Gene3D G3DSA:3.30.2090.10 181 269 9.8E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82714 183 265 9.29E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 Gene3D G3DSA:3.30.70.1430 560 655 3.7E-12 T 28-03-2018 hmeg3_RS15960 0cf6d59e4d7b517b1687bf28112ea4fd 1081 SUPERFAMILY SSF82866 853 1050 3.92E-41 T 28-03-2018 hmeg3_RS13250 decddf3f598d7da64493821260d91cba 419 SUPERFAMILY SSF102114 44 417 1.44E-106 T 28-03-2018 hmeg3_RS13250 decddf3f598d7da64493821260d91cba 419 Pfam PF06969 HemN C-terminal domain 348 406 2.5E-8 T 28-03-2018 IPR010723 HemN, C-terminal hmeg3_RS13250 decddf3f598d7da64493821260d91cba 419 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 46 386 2.6E-109 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 hmeg3_RS13250 decddf3f598d7da64493821260d91cba 419 Gene3D G3DSA:3.20.20.70 42 346 4.0E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS13250 decddf3f598d7da64493821260d91cba 419 SMART SM00729 45 264 4.3E-49 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS13250 decddf3f598d7da64493821260d91cba 419 Pfam PF04055 Radical SAM superfamily 50 215 1.0E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 Gene3D G3DSA:1.10.287.130 205 276 8.0E-16 T 28-03-2018 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 Gene3D G3DSA:3.30.565.10 282 431 8.2E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 SUPERFAMILY SSF55874 270 429 4.98E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 SUPERFAMILY SSF47384 198 279 3.34E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 280 8.5E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 429 2.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 1.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 374 1.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 388 1.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 Gene3D G3DSA:1.20.5.1040 2 59 3.8E-11 T 28-03-2018 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 Gene3D G3DSA:1.20.5.1040 112 162 2.8E-8 T 28-03-2018 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 SMART SM00388 215 280 2.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02025 fbe5bfa39c564c64f51ec1ca294db57b 432 SMART SM00387 323 431 6.5E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 Gene3D G3DSA:3.50.50.60 158 336 1.5E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 SUPERFAMILY SSF51905 20 324 6.33E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.0E-14 T 28-03-2018 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.0E-14 T 28-03-2018 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 1.0E-14 T 28-03-2018 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 1.0E-14 T 28-03-2018 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 1.0E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 77 87 1.0E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 1.0E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 164 188 1.0E-12 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 309 2.4E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 Hamap MF_01685 Ferredoxin--NADP reductase. 18 345 40.947 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 hmeg3_RS14595 007297c087791563a2ebdd986e3b8b1c 360 Gene3D G3DSA:3.50.50.60 13 155 1.9E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS05685 78eb8dd6d5edb115b0c67029dfe8fcc6 627 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 219 623 3.3E-85 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS05685 78eb8dd6d5edb115b0c67029dfe8fcc6 627 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 44 169 7.6E-29 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component hmeg3_RS05685 78eb8dd6d5edb115b0c67029dfe8fcc6 627 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 211 621 7.5E-93 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 Gene3D G3DSA:3.30.70.270 398 576 1.4E-51 T 28-03-2018 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 SUPERFAMILY SSF55073 410 568 4.63E-44 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 Pfam PF00672 HAMP domain 333 378 7.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 Gene3D G3DSA:3.30.450.20 68 188 1.9E-12 T 28-03-2018 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 Pfam PF02743 Cache domain 62 294 7.0E-22 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 Pfam PF00990 Diguanylate cyclase, GGDEF domain 407 566 6.6E-44 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 Gene3D G3DSA:3.30.450.20 189 311 1.4E-15 T 28-03-2018 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 SUPERFAMILY SSF158472 333 379 3.92E-5 T 28-03-2018 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 SMART SM00304 332 385 0.0022 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 SMART SM00267 394 570 1.1E-58 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20700 593aea9395bddaba2dd50c9d5372a237 578 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 401 569 3.7E-48 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11195 36803dd36f8d6466c0d83b36bf65acbd 191 Pfam PF16157 Domain of unknown function (DUF4865) 1 179 5.2E-50 T 28-03-2018 IPR032349 Protein of unknown function DUF4865 hmeg3_RS19550 0aee3a42d0c9e509aeeb6551634949e7 134 Pfam PF01042 Endoribonuclease L-PSP 17 129 1.8E-25 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS19550 0aee3a42d0c9e509aeeb6551634949e7 134 Gene3D G3DSA:3.30.1330.40 5 134 3.7E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS19550 0aee3a42d0c9e509aeeb6551634949e7 134 SUPERFAMILY SSF55298 8 132 2.36E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS13605 89e11040497b0f74daceb6f7869fadcb 223 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 5 186 2.5E-56 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 hmeg3_RS13605 89e11040497b0f74daceb6f7869fadcb 223 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 200 34.653 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 hmeg3_RS13605 89e11040497b0f74daceb6f7869fadcb 223 Pfam PF00694 Aconitase C-terminal domain 5 122 4.5E-31 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13605 89e11040497b0f74daceb6f7869fadcb 223 Gene3D G3DSA:3.20.19.10 1 174 1.4E-41 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS13605 89e11040497b0f74daceb6f7869fadcb 223 SUPERFAMILY SSF52016 5 190 8.63E-50 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 116 301 1.6E-8 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 368 431 6.2E-5 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 SUPERFAMILY SSF52518 481 707 1.96E-92 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 SUPERFAMILY SSF52518 64 474 4.72E-137 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 Gene3D G3DSA:3.40.50.970 63 476 2.9E-85 T 28-03-2018 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 SUPERFAMILY SSF52922 710 896 3.49E-57 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 12 897 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 Gene3D G3DSA:3.40.50.920 714 898 4.2E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 Gene3D G3DSA:3.40.50.970 478 713 1.0E-59 T 28-03-2018 hmeg3_RS17570 ba692e843cdc8ec832892ed2405a5cb8 898 PIRSF PIRSF000156 3 898 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 SUPERFAMILY SSF54292 38 114 1.44E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 SUPERFAMILY SSF47741 120 186 1.31E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 43 96 2.1E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 75 83 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 Pfam PF01799 [2Fe-2S] binding domain 109 181 9.2E-31 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 Gene3D G3DSA:3.10.20.30 36 110 1.6E-26 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS23545 75c0f69d4d9fb64f3fc2b075a8d76fd0 188 Gene3D G3DSA:1.10.150.120 111 188 8.5E-35 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SUPERFAMILY SSF55785 12 120 1.34E-19 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 PIRSF PIRSF005925 121 253 2.6E-10 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 PIRSF PIRSF005925 243 687 2.5E-147 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 PIRSF PIRSF005925 5 120 4.5 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SMART SM00052 428 674 5.8E-123 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Gene3D G3DSA:3.30.70.270 272 425 7.3E-61 T 28-03-2018 hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 416 5.1E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SUPERFAMILY SSF55785 137 242 3.87E-27 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Pfam PF13426 PAS domain 143 244 4.1E-15 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Gene3D G3DSA:3.30.450.20 134 271 6.9E-27 T 28-03-2018 hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Gene3D G3DSA:3.30.450.20 9 133 1.6E-20 T 28-03-2018 hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SMART SM00267 246 418 3.5E-66 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SMART SM00091 10 77 1.2E-7 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SMART SM00091 132 198 5.1E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Pfam PF00989 PAS fold 20 111 3.7E-10 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SMART SM00086 84 124 2.4 T 28-03-2018 IPR001610 PAC motif hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SMART SM00086 204 246 6.0E-7 T 28-03-2018 IPR001610 PAC motif hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SUPERFAMILY SSF55073 262 420 1.02E-50 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 SUPERFAMILY SSF141868 433 678 3.53E-91 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Pfam PF00990 Diguanylate cyclase, GGDEF domain 257 413 1.0E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 128 1.1E-18 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 253 6.1E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Gene3D G3DSA:3.20.20.450 426 678 1.7E-103 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18595 479395a83482199e5f48652a8a59ff53 688 Pfam PF00563 EAL domain 434 669 5.9E-73 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05180 b82aebeb3bbb5322cfe27b523e816fb9 210 Gene3D G3DSA:1.25.40.10 97 210 1.6E-37 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS05180 b82aebeb3bbb5322cfe27b523e816fb9 210 Gene3D G3DSA:1.20.58.320 2 96 1.7E-25 T 28-03-2018 hmeg3_RS05180 b82aebeb3bbb5322cfe27b523e816fb9 210 SUPERFAMILY SSF48452 5 206 8.72E-63 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS05180 b82aebeb3bbb5322cfe27b523e816fb9 210 Pfam PF06041 Bacterial protein of unknown function (DUF924) 10 206 1.0E-64 T 28-03-2018 IPR010323 Protein of unknown function DUF924 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 Pfam PF00108 Thiolase, N-terminal domain 4 261 8.1E-110 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 SUPERFAMILY SSF53901 3 269 1.08E-88 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.7E-150 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 Gene3D G3DSA:3.40.47.10 1 185 4.8E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 Gene3D G3DSA:3.40.47.10 186 264 8.4E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 Gene3D G3DSA:3.40.47.10 265 389 1.0E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 SUPERFAMILY SSF53901 271 391 2.37E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 PIRSF PIRSF000429 1 391 2.8E-130 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS22370 623d0ff78aa8d0aeabad74b276f818fe 391 Pfam PF02803 Thiolase, C-terminal domain 270 391 2.4E-52 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 Gene3D G3DSA:3.40.1010.10 1 120 1.0E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 Gene3D G3DSA:3.30.950.10 121 234 9.7E-25 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 249 6.5E-102 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 5.0E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 SUPERFAMILY SSF53790 2 233 4.71E-63 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12410 40d97e1be1d38368e2c8abc1598b152f 273 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 hmeg3_RS14990 98b7a52c7248869e565d2182c768511b 326 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 10 326 54.367 T 28-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 hmeg3_RS14990 98b7a52c7248869e565d2182c768511b 326 Gene3D G3DSA:3.90.420.10 63 326 3.7E-57 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS14990 98b7a52c7248869e565d2182c768511b 326 SUPERFAMILY SSF56524 74 322 4.45E-87 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS14990 98b7a52c7248869e565d2182c768511b 326 Pfam PF00174 Oxidoreductase molybdopterin binding domain 106 261 1.0E-28 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS02590 430dcbb90b8a528035acefd9ff5e0c74 89 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 9.1E-25 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor hmeg3_RS02590 430dcbb90b8a528035acefd9ff5e0c74 89 SMART SM01234 1 68 1.4E-41 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor hmeg3_RS02590 430dcbb90b8a528035acefd9ff5e0c74 89 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.265 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor hmeg3_RS02590 430dcbb90b8a528035acefd9ff5e0c74 89 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 65 5.0E-14 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor hmeg3_RS02590 430dcbb90b8a528035acefd9ff5e0c74 89 Pfam PF01809 Haemolytic domain 5 68 1.3E-27 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Gene3D G3DSA:3.30.300.20 363 436 4.9E-25 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Gene3D G3DSA:1.20.120.430 1 67 3.8E-14 T 28-03-2018 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Pfam PF01926 50S ribosome-binding GTPase 181 299 6.1E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Pfam PF01926 50S ribosome-binding GTPase 5 120 2.9E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 435 4.9E-171 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 357 435 5.2E-24 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Gene3D G3DSA:1.20.120.430 68 249 5.3E-46 T 28-03-2018 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 SUPERFAMILY SSF52540 4 163 1.0E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 PIRSF PIRSF006485 1 443 3.7E-170 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Gene3D G3DSA:1.20.120.430 250 362 4.9E-11 T 28-03-2018 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 SUPERFAMILY SSF52540 138 441 1.17E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.6E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 3.6E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 Hamap MF_00195 GTPase Der [der]. 2 438 38.17 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 3.3E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 179 343 5.3E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 SMART SM00382 178 319 0.35 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS08890 f3d858289b283599f3dbca24acb60b40 446 SMART SM00382 1 169 1.1 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS18160 918fe3250bfb5b5f28213859add856f7 235 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 151 217 1.2E-9 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS18160 918fe3250bfb5b5f28213859add856f7 235 SUPERFAMILY SSF58104 111 226 1.83E-14 T 28-03-2018 hmeg3_RS18160 918fe3250bfb5b5f28213859add856f7 235 Gene3D G3DSA:1.10.287.950 110 229 1.8E-14 T 28-03-2018 hmeg3_RS18160 918fe3250bfb5b5f28213859add856f7 235 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 36 101 4.8E-7 T 28-03-2018 IPR029095 NarX-like, N-terminal hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 71 91 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 29 52 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 331 355 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 355 378 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 412 432 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 397 412 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 298 319 5.2E-37 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 21 432 3.7E-110 T 28-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 ProSitePatterns PS00543 HlyD family secretion proteins signature. 397 419 - T 28-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 Pfam PF13437 HlyD family secretion protein 286 400 4.2E-16 T 28-03-2018 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 Gene3D G3DSA:2.40.50.100 283 373 5.9E-7 T 28-03-2018 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 Gene3D G3DSA:2.40.50.100 54 184 7.5E-7 T 28-03-2018 hmeg3_RS07595 d5e2983ebd21c2853f466d3913030fe0 434 Gene3D G3DSA:1.20.5.730 214 282 6.7E-5 T 28-03-2018 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 273 337 2.0E-27 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 Pfam PF07836 DmpG-like communication domain 275 335 1.6E-31 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 Gene3D G3DSA:3.20.20.70 6 281 1.9E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 SUPERFAMILY SSF89000 289 338 2.9E-19 T 28-03-2018 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 Pfam PF00682 HMGL-like 6 263 4.6E-72 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 SUPERFAMILY SSF51569 2 277 4.58E-65 T 28-03-2018 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 Gene3D G3DSA:1.10.8.60 282 338 1.6E-33 T 28-03-2018 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 344 218.946 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 hmeg3_RS19565 974129ed6e0ba5acd22795682550002b 345 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 5 337 6.8E-176 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 hmeg3_RS08135 113099b07c9ad0d0eab884eeeda95a91 220 Gene3D G3DSA:1.10.287.500 45 177 2.0E-15 T 28-03-2018 hmeg3_RS08135 113099b07c9ad0d0eab884eeeda95a91 220 Gene3D G3DSA:1.20.5.590 15 42 1.4E-7 T 28-03-2018 hmeg3_RS08135 113099b07c9ad0d0eab884eeeda95a91 220 PIRSF PIRSF002884 10 220 2.9E-65 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 hmeg3_RS08135 113099b07c9ad0d0eab884eeeda95a91 220 SUPERFAMILY SSF75708 22 219 1.24E-57 T 28-03-2018 hmeg3_RS08135 113099b07c9ad0d0eab884eeeda95a91 220 Pfam PF04344 Chemotaxis phosphatase, CheZ 26 220 1.9E-70 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 PRINTS PR00969 Pili chaperone signature 80 101 8.6E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 PRINTS PR00969 Pili chaperone signature 108 125 8.6E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 PRINTS PR00969 Pili chaperone signature 136 151 8.6E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 PRINTS PR00969 Pili chaperone signature 31 40 8.6E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 PRINTS PR00969 Pili chaperone signature 177 192 8.6E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 SUPERFAMILY SSF49584 148 255 1.09E-14 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 Gene3D G3DSA:2.60.40.10 159 260 1.2E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 31 154 6.9E-45 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 Gene3D G3DSA:2.60.40.10 30 155 1.8E-40 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 107 124 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 SUPERFAMILY SSF49354 26 154 4.45E-43 T 28-03-2018 IPR008962 PapD-like hmeg3_RS03825 379a692a4c41538bd57ed613d1a94808 261 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 183 253 1.6E-14 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal hmeg3_RS22645 21eb1fce541ee6d2a89c49e80973099e 245 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 217 26.182 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 hmeg3_RS22645 21eb1fce541ee6d2a89c49e80973099e 245 Gene3D G3DSA:3.40.50.300 6 226 4.4E-26 T 28-03-2018 hmeg3_RS22645 21eb1fce541ee6d2a89c49e80973099e 245 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 213 1.4E-60 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 hmeg3_RS22645 21eb1fce541ee6d2a89c49e80973099e 245 Pfam PF01926 50S ribosome-binding GTPase 26 160 3.6E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS22645 21eb1fce541ee6d2a89c49e80973099e 245 SUPERFAMILY SSF52540 14 215 5.07E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 Gene3D G3DSA:2.60.120.10 31 170 2.9E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 SUPERFAMILY SSF46785 170 250 2.04E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 Gene3D G3DSA:1.10.10.10 171 253 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 198 214 1.2E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 214 229 1.2E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 Pfam PF00027 Cyclic nucleotide-binding domain 54 140 6.3E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 Pfam PF13545 Crp-like helix-turn-helix domain 173 246 5.7E-18 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 SUPERFAMILY SSF51206 28 166 3.54E-27 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 ProSitePatterns PS00042 Crp-type HTH domain signature. 200 223 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 SMART SM00419 192 240 7.2E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS10855 08adb3f736071a4246cafd68023c9557 254 SMART SM00100 35 153 6.7E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS13430 9bb82dc941aa6e265e4ab89a23337b3c 458 Pfam PF02447 GntP family permease 18 453 1.8E-135 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS13430 9bb82dc941aa6e265e4ab89a23337b3c 458 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 19 454 6.2E-128 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS13430 9bb82dc941aa6e265e4ab89a23337b3c 458 PIRSF PIRSF002746 12 458 1.9E-138 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 Pfam PF00990 Diguanylate cyclase, GGDEF domain 344 489 1.4E-32 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 Gene3D G3DSA:3.30.450.20 168 345 8.9E-20 T 28-03-2018 hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 SUPERFAMILY SSF55785 238 339 7.61E-11 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 Pfam PF13188 PAS domain 185 283 1.3E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 Pfam PF13188 PAS domain 29 123 6.9E-4 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 Gene3D G3DSA:3.30.450.20 26 167 8.5E-9 T 28-03-2018 hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 339 491 6.9E-30 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 SUPERFAMILY SSF55073 348 490 1.57E-31 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 Gene3D G3DSA:3.30.70.270 346 500 1.0E-37 T 28-03-2018 hmeg3_RS13915 a1c857f050dacf9eb3ef308d790f63ee 506 SMART SM00267 332 494 8.4E-30 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 Gene3D G3DSA:1.10.10.60 198 255 2.9E-6 T 28-03-2018 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 269 284 1.9E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 300 1.9E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 SUPERFAMILY SSF46689 255 302 2.87E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 Pfam PF12833 Helix-turn-helix domain 223 301 7.6E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 SUPERFAMILY SSF51182 44 106 1.47E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 SMART SM00342 217 300 2.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 Gene3D G3DSA:1.10.10.60 256 303 8.0E-14 T 28-03-2018 hmeg3_RS01250 7a6a8e5887ca398327991f686e65daad 306 Gene3D G3DSA:2.60.120.280 23 186 2.3E-10 T 28-03-2018 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 5.4E-132 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PRINTS PR00148 Enolase signature 363 380 2.2E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PRINTS PR00148 Enolase signature 311 322 2.2E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PRINTS PR00148 Enolase signature 161 174 2.2E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PRINTS PR00148 Enolase signature 37 51 2.2E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PRINTS PR00148 Enolase signature 334 348 2.2E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PRINTS PR00148 Enolase signature 107 123 2.2E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 PIRSF PIRSF001400 1 425 1.4E-188 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 1.4E-207 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 SUPERFAMILY SSF54826 4 136 7.95E-55 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 Gene3D G3DSA:3.20.20.120 128 427 7.9E-103 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 SMART SM01192 139 425 2.4E-222 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 SUPERFAMILY SSF51604 139 426 5.23E-130 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 Pfam PF03952 Enolase, N-terminal domain 4 133 1.3E-57 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 SMART SM01193 4 134 8.1E-93 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 Hamap MF_00318 Enolase [eno]. 2 411 44.545 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS09275 7f3160d8ffb1bf4b56ab14f3da8a96da 427 Gene3D G3DSA:3.30.390.10 3 127 4.9E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS05990 05938b26c47b77dcf8a9116bccef51ab 398 Gene3D G3DSA:3.90.1300.10 7 396 2.1E-92 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS05990 05938b26c47b77dcf8a9116bccef51ab 398 SUPERFAMILY SSF75304 12 394 9.16E-88 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS05990 05938b26c47b77dcf8a9116bccef51ab 398 Pfam PF01425 Amidase 278 384 1.8E-7 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS05990 05938b26c47b77dcf8a9116bccef51ab 398 Pfam PF01425 Amidase 27 204 2.4E-50 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 7 352 5.6E-127 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 3.9E-40 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 3.9E-40 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 3.9E-40 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 3.9E-40 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 3.9E-40 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 Gene3D G3DSA:3.40.1690.10 218 353 3.9E-58 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 347 8.4E-127 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS08140 fe87c5574d2451e75ac1a22707cf7772 393 SUPERFAMILY SSF160544 244 351 6.02E-41 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 Gene3D G3DSA:3.40.50.300 9 264 8.9E-75 T 28-03-2018 hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 SMART SM00382 36 219 1.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 SUPERFAMILY SSF50331 244 354 8.99E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 Gene3D G3DSA:2.40.50.140 278 339 2.9E-15 T 28-03-2018 hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 Pfam PF00005 ABC transporter 28 169 5.8E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 Pfam PF08402 TOBE domain 275 346 1.3E-16 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 SUPERFAMILY SSF52540 12 250 7.78E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10975 a6b086fd45fe53495fc3fe14af07b43b 355 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS13795 fadcdc176566ad879bdbe7e3170d2d8f 124 Pfam PF03840 Preprotein translocase SecG subunit 7 75 1.9E-19 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 hmeg3_RS13795 fadcdc176566ad879bdbe7e3170d2d8f 124 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 3.5E-35 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 hmeg3_RS13795 fadcdc176566ad879bdbe7e3170d2d8f 124 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 3.5E-35 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 hmeg3_RS13795 fadcdc176566ad879bdbe7e3170d2d8f 124 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 3.5E-35 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 hmeg3_RS13795 fadcdc176566ad879bdbe7e3170d2d8f 124 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 3.5E-35 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 hmeg3_RS13795 fadcdc176566ad879bdbe7e3170d2d8f 124 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 1.4E-24 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 hmeg3_RS04125 4687cf783eebc821cf480a5a22e27a52 312 Gene3D G3DSA:3.90.226.10 37 247 3.7E-42 T 28-03-2018 hmeg3_RS04125 4687cf783eebc821cf480a5a22e27a52 312 Gene3D G3DSA:1.10.12.10 248 312 1.5E-7 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS04125 4687cf783eebc821cf480a5a22e27a52 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 61 311 1.3E-34 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS04125 4687cf783eebc821cf480a5a22e27a52 312 SUPERFAMILY SSF52096 52 312 9.09E-55 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS15325 15145894f202a72639dd0360fcfe172d 123 Gene3D G3DSA:2.40.50.140 11 123 7.2E-19 T 28-03-2018 hmeg3_RS15325 15145894f202a72639dd0360fcfe172d 123 Pfam PF01588 Putative tRNA binding domain 25 120 1.6E-13 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 hmeg3_RS15325 15145894f202a72639dd0360fcfe172d 123 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 17 122 2.1E-46 T 28-03-2018 IPR008231 Probable chaperone CsaA hmeg3_RS15325 15145894f202a72639dd0360fcfe172d 123 SUPERFAMILY SSF50249 15 122 4.16E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS06625 cc9c22474592e93ab7f8827c8090c8ae 417 SMART SM01329 29 413 3.7E-171 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS06625 cc9c22474592e93ab7f8827c8090c8ae 417 Gene3D G3DSA:3.40.718.10 9 417 1.9E-130 T 28-03-2018 hmeg3_RS06625 cc9c22474592e93ab7f8827c8090c8ae 417 SUPERFAMILY SSF53659 2 417 4.03E-144 T 28-03-2018 hmeg3_RS06625 cc9c22474592e93ab7f8827c8090c8ae 417 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 1 417 8.6E-219 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 hmeg3_RS06625 cc9c22474592e93ab7f8827c8090c8ae 417 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 304 323 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS06625 cc9c22474592e93ab7f8827c8090c8ae 417 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 413 2.4E-113 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS06975 87cc2d7a96765d12b7728a5d6e4fd9d3 213 Gene3D G3DSA:3.40.50.10610 16 211 2.0E-49 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component hmeg3_RS06975 87cc2d7a96765d12b7728a5d6e4fd9d3 213 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 43 196 1.9E-39 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component hmeg3_RS06975 87cc2d7a96765d12b7728a5d6e4fd9d3 213 SUPERFAMILY SSF159594 45 203 5.23E-33 T 28-03-2018 hmeg3_RS24160 84568130018cb1022eb0330bef470921 256 Pfam PF13614 AAA domain 3 178 1.3E-63 T 28-03-2018 IPR025669 AAA domain hmeg3_RS24160 84568130018cb1022eb0330bef470921 256 SUPERFAMILY SSF52540 1 254 2.39E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24160 84568130018cb1022eb0330bef470921 256 Gene3D G3DSA:3.40.50.300 1 256 3.6E-59 T 28-03-2018 hmeg3_RS24160 84568130018cb1022eb0330bef470921 256 PIRSF PIRSF009320 86 255 3.8E-9 T 28-03-2018 hmeg3_RS24160 84568130018cb1022eb0330bef470921 256 PIRSF PIRSF009320 2 54 1.2E-13 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Gene3D G3DSA:3.30.870.10 333 512 1.7E-22 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 21 692 1.5E-279 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 SUPERFAMILY SSF56024 329 508 2.64E-56 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 SUPERFAMILY SSF140356 19 119 1.57E-28 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Pfam PF02503 Polyphosphate kinase middle domain 133 336 9.5E-61 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Gene3D G3DSA:3.30.1840.10 123 320 5.7E-61 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Pfam PF13090 Polyphosphate kinase C-terminal domain 343 691 2.9E-151 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 SUPERFAMILY SSF56024 513 693 1.26E-67 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 SUPERFAMILY SSF143724 121 326 3.92E-61 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Gene3D G3DSA:1.20.58.310 23 122 3.6E-30 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Pfam PF13089 Polyphosphate kinase N-terminal domain 21 123 4.0E-31 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 PIRSF PIRSF015589 2 698 5.3E-267 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Gene3D G3DSA:3.30.870.10 513 698 1.4E-32 T 28-03-2018 hmeg3_RS06170 05a7feeb977b8e65941992cf37470066 703 Hamap MF_00347 Polyphosphate kinase [ppk]. 19 696 28.209 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 hmeg3_RS18450 20f33118df007722f136b2bb21ae9721 156 Pfam PF07681 DoxX 33 116 9.8E-11 T 28-03-2018 IPR032808 DoxX family hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Gene3D G3DSA:3.30.365.10 463 623 2.9E-50 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 SUPERFAMILY SSF56003 144 781 2.22E-201 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 SUPERFAMILY SSF54665 14 144 1.31E-44 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 23 784 0.0 T 28-03-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Gene3D G3DSA:3.30.365.10 166 274 3.0E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 165 713 2.0E-195 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 37 144 8.1E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Gene3D G3DSA:3.30.365.10 624 785 1.8E-59 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 SMART SM01008 37 144 9.4E-51 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Gene3D G3DSA:3.90.1170.50 21 144 3.4E-35 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS17080 52babf180e5d6e6824993431dc9b6f4c 790 Gene3D G3DSA:3.30.365.10 275 443 2.2E-51 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 276 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 Gene3D G3DSA:3.90.1150.10 319 432 2.9E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 Gene3D G3DSA:3.40.640.10 191 318 1.1E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 Gene3D G3DSA:3.90.1150.10 4 190 2.1E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 SUPERFAMILY SSF53383 7 429 4.03E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 Pfam PF00202 Aminotransferase class-III 38 401 1.2E-75 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 9 431 101.978 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 hmeg3_RS04740 070970999a48f595c3d21b6ff942e761 432 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 10 430 2.9E-186 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 hmeg3_RS24210 3b89d2e467d2ace5aafd75c07a919f17 249 Gene3D G3DSA:3.40.50.300 13 249 2.9E-50 T 28-03-2018 hmeg3_RS24210 3b89d2e467d2ace5aafd75c07a919f17 249 SUPERFAMILY SSF52540 17 241 3.62E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24210 3b89d2e467d2ace5aafd75c07a919f17 249 Pfam PF00005 ABC transporter 34 176 1.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24210 3b89d2e467d2ace5aafd75c07a919f17 249 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24210 3b89d2e467d2ace5aafd75c07a919f17 249 SMART SM00382 43 228 8.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03580 c9300651335b5fab78b9645d33cd46a5 203 Gene3D G3DSA:3.40.30.10 1 87 5.9E-28 T 28-03-2018 hmeg3_RS03580 c9300651335b5fab78b9645d33cd46a5 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 188 2.6E-8 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS03580 c9300651335b5fab78b9645d33cd46a5 203 SUPERFAMILY SSF47616 80 200 4.69E-23 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS03580 c9300651335b5fab78b9645d33cd46a5 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 4.9E-18 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS03580 c9300651335b5fab78b9645d33cd46a5 203 SUPERFAMILY SSF52833 1 101 2.1E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03580 c9300651335b5fab78b9645d33cd46a5 203 Gene3D G3DSA:1.20.1050.10 88 203 8.8E-22 T 28-03-2018 hmeg3_RS18865 bb1af8679ddb64b03eeefb74958ecb97 499 Pfam PF00474 Sodium:solute symporter family 50 433 4.8E-19 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SMART SM00388 327 392 1.4E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Gene3D G3DSA:1.10.287.130 297 388 2.1E-9 T 28-03-2018 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Gene3D G3DSA:3.40.50.2300 565 700 3.4E-30 T 28-03-2018 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SUPERFAMILY SSF55785 162 269 1.21E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SUPERFAMILY SSF52172 572 692 3.56E-32 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SUPERFAMILY SSF47384 321 389 2.35E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Pfam PF08447 PAS fold 175 259 6.5E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SMART SM00448 572 681 5.7E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Pfam PF00512 His Kinase A (phospho-acceptor) domain 329 390 4.8E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 548 6.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Gene3D G3DSA:3.40.50.2300 3 124 0.14 T 28-03-2018 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Gene3D G3DSA:3.30.450.20 125 296 5.3E-21 T 28-03-2018 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SMART SM00387 433 550 9.5E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 SUPERFAMILY SSF55874 382 548 3.41E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 1.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 1.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 1.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 1.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 148 273 3.4E-7 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Pfam PF00072 Response regulator receiver domain 574 680 4.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11280 05a0ac97357b6493a526b1275e4216f0 702 Gene3D G3DSA:3.30.565.10 390 550 1.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09225 011e93f3ea0dcc501efb2f1ed2b0f233 359 PIRSF PIRSF015283 1 352 1.3E-75 T 28-03-2018 IPR016631 Regulatory, RpfE hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 SUPERFAMILY SSF56003 329 734 9.81E-100 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 52 190 2.5E-11 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 611 688 6.0E-9 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 325 567 3.1E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Gene3D G3DSA:3.30.365.10 342 436 7.6E-25 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Gene3D G3DSA:3.90.1170.50 194 341 8.4E-25 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Gene3D G3DSA:3.30.365.10 437 599 2.9E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 SUPERFAMILY SSF56003 37 249 2.02E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Gene3D G3DSA:3.30.365.10 34 193 7.0E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 Gene3D G3DSA:3.30.365.10 600 737 2.4E-26 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 PIRSF PIRSF036389 7 738 1.8E-208 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related hmeg3_RS01060 8f4e120b061ea6759266eeada91c1614 738 SMART SM01008 217 303 8.0E-18 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 SUPERFAMILY SSF51735 1 158 1.21E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 Pfam PF00742 Homoserine dehydrogenase 137 315 3.8E-66 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 Pfam PF01842 ACT domain 354 420 4.7E-14 T 28-03-2018 IPR002912 ACT domain hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 Gene3D G3DSA:3.40.50.720 1 157 1.3E-34 T 28-03-2018 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 SUPERFAMILY SSF55347 137 302 8.5E-54 T 28-03-2018 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 5.5E-20 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 Gene3D G3DSA:3.30.360.10 158 298 4.6E-54 T 28-03-2018 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 Gene3D G3DSA:3.30.70.260 350 431 2.7E-19 T 28-03-2018 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 PIRSF PIRSF000098 1 435 2.0E-165 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 hmeg3_RS08470 1c9b8eadb3fe132a923f1a404bba9deb 436 SUPERFAMILY SSF55021 353 423 4.01E-13 T 28-03-2018 hmeg3_RS15065 da63d11f956133b082afe7f919eed3e8 141 Gene3D G3DSA:2.20.25.10 4 47 4.8E-20 T 28-03-2018 hmeg3_RS15065 da63d11f956133b082afe7f919eed3e8 141 SUPERFAMILY SSF82784 1 140 1.57E-45 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS15065 da63d11f956133b082afe7f919eed3e8 141 Pfam PF02566 OsmC-like protein 43 138 1.1E-16 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS15065 da63d11f956133b082afe7f919eed3e8 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 3.4E-56 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 hmeg3_RS15065 da63d11f956133b082afe7f919eed3e8 141 Gene3D G3DSA:3.30.300.20 48 141 6.6E-23 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS12415 0cf17637df0e0f3fb6aa835aaea74bfb 244 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 213 9.9E-41 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12415 0cf17637df0e0f3fb6aa835aaea74bfb 244 SUPERFAMILY SSF53790 1 233 1.7E-34 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12415 0cf17637df0e0f3fb6aa835aaea74bfb 244 Gene3D G3DSA:3.40.1010.10 1 147 4.4E-22 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12415 0cf17637df0e0f3fb6aa835aaea74bfb 244 PIRSF PIRSF036427 1 242 1.5E-59 T 28-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 hmeg3_RS12415 0cf17637df0e0f3fb6aa835aaea74bfb 244 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 2 235 3.2E-64 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 hmeg3_RS13620 e10696175d31ba3518090cad04ee6200 399 Pfam PF07690 Major Facilitator Superfamily 3 357 1.0E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS13620 e10696175d31ba3518090cad04ee6200 399 SUPERFAMILY SSF103473 1 393 3.01E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS13620 e10696175d31ba3518090cad04ee6200 399 Gene3D G3DSA:1.20.1250.20 204 398 2.0E-19 T 28-03-2018 hmeg3_RS13620 e10696175d31ba3518090cad04ee6200 399 Gene3D G3DSA:1.20.1250.20 1 190 5.6E-30 T 28-03-2018 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 13 259 7.4E-57 T 28-03-2018 IPR013360 Pilus biogenesis/stability type IV, PilW hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 Gene3D G3DSA:1.25.40.10 24 118 5.8E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 Gene3D G3DSA:1.25.40.10 141 208 2.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 Pfam PF13181 Tetratricopeptide repeat 161 192 0.086 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 Gene3D G3DSA:1.25.40.10 209 274 0.042 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 SMART SM00028 90 123 1.8E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 SMART SM00028 56 89 100.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 SMART SM00028 160 193 8.8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 Gene3D G3DSA:1.25.40.10 119 140 4.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 SUPERFAMILY SSF48452 56 154 4.17E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 SUPERFAMILY SSF48452 125 246 6.26E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08860 dbe3908e90e397db6516669285c13412 274 Pfam PF13432 Tetratricopeptide repeat 96 155 6.2E-7 T 28-03-2018 hmeg3_RS17895 6b587b4c908c772ff174098c878b90ea 345 Pfam PF13379 NMT1-like family 33 263 1.4E-26 T 28-03-2018 hmeg3_RS17895 6b587b4c908c772ff174098c878b90ea 345 Gene3D G3DSA:3.40.190.10 31 137 1.4E-14 T 28-03-2018 hmeg3_RS17895 6b587b4c908c772ff174098c878b90ea 345 Gene3D G3DSA:3.40.190.10 138 341 2.5E-27 T 28-03-2018 hmeg3_RS17895 6b587b4c908c772ff174098c878b90ea 345 SUPERFAMILY SSF53850 35 284 3.72E-44 T 28-03-2018 hmeg3_RS17895 6b587b4c908c772ff174098c878b90ea 345 SMART SM00062 35 281 0.0039 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04045 fe3cbbb444dbf9ad6f2f1d216f91085e 183 Gene3D G3DSA:3.40.50.1000 14 180 5.8E-28 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04045 fe3cbbb444dbf9ad6f2f1d216f91085e 183 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 19 172 2.3E-51 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 hmeg3_RS04045 fe3cbbb444dbf9ad6f2f1d216f91085e 183 SUPERFAMILY SSF56784 16 176 1.65E-40 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04045 fe3cbbb444dbf9ad6f2f1d216f91085e 183 Pfam PF08282 haloacid dehalogenase-like hydrolase 91 162 2.0E-8 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04045 fe3cbbb444dbf9ad6f2f1d216f91085e 183 PIRSF PIRSF006118 6 182 4.1E-67 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00184 Neisseria sp. porin signature 51 76 1.1E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00184 Neisseria sp. porin signature 148 165 1.1E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00184 Neisseria sp. porin signature 310 334 1.1E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 Gene3D G3DSA:2.40.160.10 7 367 1.3E-69 T 28-03-2018 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 Pfam PF13609 Gram-negative porin 9 334 3.3E-42 T 28-03-2018 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 SUPERFAMILY SSF56935 19 206 7.33E-79 T 28-03-2018 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 SUPERFAMILY SSF56935 234 367 7.33E-79 T 28-03-2018 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 149 160 1.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 93 103 1.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 313 330 1.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19125 a37d876d01229edf433a9e234c5a4d46 367 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 49 60 1.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 SUPERFAMILY SSF53187 384 472 2.69E-45 T 28-03-2018 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 SUPERFAMILY SSF53187 29 223 2.69E-45 T 28-03-2018 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 137 176 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 Pfam PF01546 Peptidase family M20/M25/M40 103 469 1.6E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 Gene3D G3DSA:3.30.70.360 228 381 1.2E-19 T 28-03-2018 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 Gene3D G3DSA:3.40.630.10 26 227 1.3E-31 T 28-03-2018 hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 SUPERFAMILY SSF55031 318 369 2.56E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 SUPERFAMILY SSF55031 227 272 2.56E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS04605 30b893152736b43678e581abde961ef3 473 Pfam PF07687 Peptidase dimerisation domain 221 370 1.9E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 308 51.721 T 28-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 SUPERFAMILY SSF51735 6 139 1.36E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 SMART SM00859 5 106 3.0E-15 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 4 306 1.0E-123 T 28-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 Gene3D G3DSA:3.30.360.10 125 289 9.9E-46 T 28-03-2018 hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 SUPERFAMILY SSF55347 117 289 3.27E-38 T 28-03-2018 hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 Gene3D G3DSA:3.40.50.720 8 124 7.0E-20 T 28-03-2018 hmeg3_RS12725 3f6075f26a01566b46e86eddcbe37433 309 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 45 100 8.8E-10 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS14800 d19463730dbb59d10ae1ad8c5081330f 110 SUPERFAMILY SSF103481 10 107 9.94E-6 T 28-03-2018 hmeg3_RS14800 d19463730dbb59d10ae1ad8c5081330f 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 107 1.6E-35 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 hmeg3_RS14800 d19463730dbb59d10ae1ad8c5081330f 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 108 22.415 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 hmeg3_RS22300 ef82069924302fc053064a7fecf076e7 243 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 71 242 6.0E-88 T 28-03-2018 IPR018655 Protein of unknown function DUF2086 hmeg3_RS22300 ef82069924302fc053064a7fecf076e7 243 Gene3D G3DSA:2.60.120.620 20 243 5.1E-28 T 28-03-2018 hmeg3_RS04750 cc205720d0a0fec9d6a7bdfe5a825145 50 ProSitePatterns PS00202 Rubredoxin signature. 29 39 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 hmeg3_RS04750 cc205720d0a0fec9d6a7bdfe5a825145 50 Gene3D G3DSA:2.20.28.10 1 49 2.7E-23 T 28-03-2018 hmeg3_RS04750 cc205720d0a0fec9d6a7bdfe5a825145 50 PIRSF PIRSF000071 1 50 2.0E-24 T 28-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 hmeg3_RS04750 cc205720d0a0fec9d6a7bdfe5a825145 50 Pfam PF00301 Rubredoxin 1 45 3.6E-22 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 hmeg3_RS04750 cc205720d0a0fec9d6a7bdfe5a825145 50 SUPERFAMILY SSF57802 1 48 3.2E-21 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 1.3E-13 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 1.3E-13 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 1.3E-13 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 1.3E-13 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 Gene3D G3DSA:3.50.50.60 6 124 2.1E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 8.0E-22 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 8.0E-22 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 8.0E-22 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 8.0E-22 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 8.0E-22 T 28-03-2018 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 SUPERFAMILY SSF51905 157 315 2.85E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 292 4.6E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 Gene3D G3DSA:3.50.50.60 198 325 2.2E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 SUPERFAMILY SSF51905 13 201 2.16E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13200 e908f56a6adb6d3623e434e19541f89d 420 Gene3D G3DSA:3.50.50.60 125 197 1.8E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10000 341c57007801c53d0de56a2d207a3cec 383 Gene3D G3DSA:3.40.50.2000 163 356 6.3E-18 T 28-03-2018 hmeg3_RS10000 341c57007801c53d0de56a2d207a3cec 383 SUPERFAMILY SSF53756 2 349 1.33E-28 T 28-03-2018 hmeg3_RS10000 341c57007801c53d0de56a2d207a3cec 383 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 1 369 2.4E-98 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 hmeg3_RS10000 341c57007801c53d0de56a2d207a3cec 383 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 1 373 33.552 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 hmeg3_RS10000 341c57007801c53d0de56a2d207a3cec 383 Pfam PF02684 Lipid-A-disaccharide synthetase 1 347 8.3E-95 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 Gene3D G3DSA:3.90.100.10 638 754 9.5E-35 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 1.6E-38 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 PIRSF PIRSF009393 1 754 2.7E-278 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 SUPERFAMILY SSF53383 151 602 1.57E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 Gene3D G3DSA:3.40.640.10 151 458 3.3E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 583 6.5E-151 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 Gene3D G3DSA:3.90.1150.10 459 637 1.8E-70 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 610 739 3.7E-45 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 hmeg3_RS17735 e58333dce3f9cd39721a6c88eb5193ad 754 SUPERFAMILY SSF55904 605 754 2.09E-44 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 SUPERFAMILY SSF81901 242 395 1.83E-15 T 28-03-2018 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 SMART SM00671 315 350 8.1 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 SMART SM00671 351 387 110.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 SMART SM00671 236 269 160.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 SMART SM00671 18 54 3.4E-5 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Gene3D G3DSA:2.60.40.1180 366 397 0.029 T 28-03-2018 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Gene3D G3DSA:2.60.40.1180 2 88 1.3E-8 T 28-03-2018 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Gene3D G3DSA:2.60.40.1180 295 359 0.013 T 28-03-2018 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Gene3D G3DSA:2.60.40.1180 194 289 0.15 T 28-03-2018 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 SUPERFAMILY SSF81901 13 137 9.59E-11 T 28-03-2018 hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Pfam PF08238 Sel1 repeat 76 90 160.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Pfam PF08238 Sel1 repeat 18 53 2.9E-6 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Pfam PF08238 Sel1 repeat 296 313 210.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Pfam PF08238 Sel1 repeat 372 387 0.011 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02235 e7b3217b2017e89fb5d7b43685c14882 519 Pfam PF08238 Sel1 repeat 333 349 7.3 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS07570 773247d179dceacfaac7b37b3be28825 210 SUPERFAMILY SSF55729 6 150 1.5E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS07570 773247d179dceacfaac7b37b3be28825 210 Gene3D G3DSA:3.40.630.30 2 183 2.4E-27 T 28-03-2018 hmeg3_RS07570 773247d179dceacfaac7b37b3be28825 210 Pfam PF13302 Acetyltransferase (GNAT) domain 9 150 7.0E-33 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS21140 9a7ad126e8df5139f6fdd0a16e2fef53 423 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 213 2.5E-60 T 28-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 hmeg3_RS21140 9a7ad126e8df5139f6fdd0a16e2fef53 423 Gene3D G3DSA:3.20.20.70 81 221 0.16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS21140 9a7ad126e8df5139f6fdd0a16e2fef53 423 SUPERFAMILY SSF53756 60 407 5.73E-14 T 28-03-2018 hmeg3_RS21140 9a7ad126e8df5139f6fdd0a16e2fef53 423 Gene3D G3DSA:3.40.50.2000 222 407 7.6E-14 T 28-03-2018 hmeg3_RS09780 0be2c4c7c600bdebf5d34421b8f2f69e 336 Gene3D G3DSA:3.40.470.10 136 336 4.2E-57 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS09780 0be2c4c7c600bdebf5d34421b8f2f69e 336 Pfam PF03167 Uracil DNA glycosylase superfamily 172 324 3.0E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS09780 0be2c4c7c600bdebf5d34421b8f2f69e 336 SUPERFAMILY SSF52141 147 329 1.14E-56 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS09780 0be2c4c7c600bdebf5d34421b8f2f69e 336 SMART SM00987 172 325 2.0E-40 T 28-03-2018 hmeg3_RS09780 0be2c4c7c600bdebf5d34421b8f2f69e 336 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 158 325 1.0E-53 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 hmeg3_RS09780 0be2c4c7c600bdebf5d34421b8f2f69e 336 SMART SM00986 172 325 2.0E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 Gene3D G3DSA:3.40.50.2000 274 472 6.2E-37 T 28-03-2018 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 Pfam PF08323 Starch synthase catalytic domain 4 245 2.2E-59 T 28-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 Hamap MF_00484 Glycogen synthase [glgA]. 3 489 38.14 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 4 488 5.9E-141 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 Gene3D G3DSA:3.40.50.2000 2 273 1.5E-7 T 28-03-2018 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 Pfam PF00534 Glycosyl transferases group 1 305 461 1.5E-18 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 hmeg3_RS11315 3ae4bf3d5ba998f8e19b89f68f40bebc 517 SUPERFAMILY SSF53756 4 489 1.5E-102 T 28-03-2018 hmeg3_RS02165 c0e4391216e4a36e2d40da9eb391120b 310 Pfam PF01545 Cation efflux family 18 209 1.4E-43 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 hmeg3_RS02165 c0e4391216e4a36e2d40da9eb391120b 310 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 290 1.2E-89 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 hmeg3_RS02165 c0e4391216e4a36e2d40da9eb391120b 310 SUPERFAMILY SSF160240 215 288 5.36E-7 T 28-03-2018 hmeg3_RS02165 c0e4391216e4a36e2d40da9eb391120b 310 Gene3D G3DSA:3.30.70.1350 212 291 4.9E-12 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain hmeg3_RS02165 c0e4391216e4a36e2d40da9eb391120b 310 Gene3D G3DSA:1.20.1510.10 13 209 1.1E-55 T 28-03-2018 hmeg3_RS02165 c0e4391216e4a36e2d40da9eb391120b 310 SUPERFAMILY SSF161111 12 210 2.22E-56 T 28-03-2018 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Pfam PF00158 Sigma-54 interaction domain 150 315 1.7E-63 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Gene3D G3DSA:1.10.10.60 404 441 3.0E-13 T 28-03-2018 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 SUPERFAMILY SSF46689 395 441 2.51E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 SUPERFAMILY SSF52540 150 385 1.65E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 SUPERFAMILY SSF52172 13 194 7.83E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 SMART SM00382 170 316 2.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 SMART SM00448 10 121 1.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Gene3D G3DSA:3.40.50.300 148 320 8.9E-24 T 28-03-2018 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 235 250 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Gene3D G3DSA:3.40.50.2300 1 147 8.3E-28 T 28-03-2018 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Pfam PF00072 Response regulator receiver domain 13 120 2.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 1.8E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 1.8E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Pfam PF02954 Bacterial regulatory protein, Fis family 401 439 6.9E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 174 187 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS07415 1d9152dea8bd41d62ca14687ea991299 445 Gene3D G3DSA:1.10.8.60 321 403 2.7E-20 T 28-03-2018 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 SMART SM00283 266 513 8.3E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 SMART SM00304 213 265 4.0E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 174 2.7E-21 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 8.3E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 Pfam PF00672 HAMP domain 215 261 1.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 2.1E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 2.1E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 2.1E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 2.1E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 Gene3D G3DSA:1.10.287.950 86 321 3.5E-20 T 28-03-2018 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 Gene3D G3DSA:1.10.287.950 322 517 3.6E-48 T 28-03-2018 hmeg3_RS07400 e9fc7fc50e9952785ebe918401d8ca4d 540 SUPERFAMILY SSF58104 233 514 1.16E-76 T 28-03-2018 hmeg3_RS00310 fefe64dbe9d799947702716eb85f8991 232 SMART SM00382 26 211 1.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00310 fefe64dbe9d799947702716eb85f8991 232 Gene3D G3DSA:3.40.50.300 1 231 3.1E-54 T 28-03-2018 hmeg3_RS00310 fefe64dbe9d799947702716eb85f8991 232 SUPERFAMILY SSF52540 2 220 2.72E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00310 fefe64dbe9d799947702716eb85f8991 232 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 232 4.1E-105 T 28-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE hmeg3_RS00310 fefe64dbe9d799947702716eb85f8991 232 Pfam PF00005 ABC transporter 17 161 2.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 SMART SM01049 32 126 4.1E-36 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 Pfam PF17200 Single Cache domain 2 37 182 4.0E-39 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 1.6E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 1.6E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 1.6E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 1.6E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 SUPERFAMILY SSF58104 242 517 2.35E-73 T 28-03-2018 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 SMART SM00283 265 512 2.2E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 Gene3D G3DSA:1.10.287.950 320 516 3.8E-51 T 28-03-2018 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 Gene3D G3DSA:1.10.287.950 184 319 1.9E-19 T 28-03-2018 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 478 1.1E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS07300 970d449d7cdda331cebc9982db5f3114 591 Gene3D G3DSA:3.30.450.20 25 183 5.6E-45 T 28-03-2018 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 316 472 3.1E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 SMART SM01049 30 122 1.0E-14 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 Gene3D G3DSA:3.30.450.20 21 172 1.5E-25 T 28-03-2018 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 SUPERFAMILY SSF58104 225 505 3.27E-71 T 28-03-2018 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 Gene3D G3DSA:1.10.287.950 313 508 9.6E-49 T 28-03-2018 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 Gene3D G3DSA:1.10.287.950 173 312 1.3E-18 T 28-03-2018 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 Pfam PF17200 Single Cache domain 2 34 176 1.2E-24 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 384 413 2.0E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 355 382 2.0E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 278 307 2.0E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 10 2.0E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 432 461 2.0E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS23965 dd1719bcba26ff1c74745831fcd9ff38 512 SMART SM00283 257 504 2.3E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS07220 0aea0d76fe96fa59eb687bc76baecdee 204 Pfam PF00994 Probable molybdopterin binding domain 14 157 2.8E-27 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS07220 0aea0d76fe96fa59eb687bc76baecdee 204 Gene3D G3DSA:3.40.980.10 6 198 4.4E-39 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS07220 0aea0d76fe96fa59eb687bc76baecdee 204 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 hmeg3_RS07220 0aea0d76fe96fa59eb687bc76baecdee 204 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 156 2.2E-36 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS07220 0aea0d76fe96fa59eb687bc76baecdee 204 SMART SM00852 13 163 1.3E-23 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS07220 0aea0d76fe96fa59eb687bc76baecdee 204 SUPERFAMILY SSF53218 11 198 5.89E-47 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS20030 cc1f6da7194cb805246ab765d48a2fd0 403 Gene3D G3DSA:3.40.50.150 105 383 6.1E-62 T 28-03-2018 hmeg3_RS20030 cc1f6da7194cb805246ab765d48a2fd0 403 PIRSF PIRSF003085 3 400 3.5E-130 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 hmeg3_RS20030 cc1f6da7194cb805246ab765d48a2fd0 403 Pfam PF02353 Mycolic acid cyclopropane synthetase 107 379 8.2E-102 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20030 cc1f6da7194cb805246ab765d48a2fd0 403 SUPERFAMILY SSF53335 117 383 2.3E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS14260 f341adcc787ae4ef5856f106246cefda 308 Gene3D G3DSA:1.10.3470.10 3 297 8.7E-53 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS14260 f341adcc787ae4ef5856f106246cefda 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 1.4E-53 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16615 b397652185cc2803779bdec146f726a1 344 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 9 341 34.194 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS16615 b397652185cc2803779bdec146f726a1 344 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 11 339 8.4E-135 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS16615 b397652185cc2803779bdec146f726a1 344 SUPERFAMILY SSF52733 14 341 4.32E-116 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS16615 b397652185cc2803779bdec146f726a1 344 Gene3D G3DSA:3.40.50.10210 68 322 4.9E-106 T 28-03-2018 hmeg3_RS16615 b397652185cc2803779bdec146f726a1 344 Gene3D G3DSA:1.10.1610.10 2 67 2.1E-26 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS16615 b397652185cc2803779bdec146f726a1 344 Pfam PF02277 Phosphoribosyltransferase 10 339 7.6E-130 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS11345 3b15a99a474ba73ef46f455b65960717 715 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 137 694 9.1E-103 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 hmeg3_RS11345 3b15a99a474ba73ef46f455b65960717 715 Gene3D G3DSA:3.20.20.80 169 710 4.3E-153 T 28-03-2018 hmeg3_RS11345 3b15a99a474ba73ef46f455b65960717 715 Pfam PF02446 4-alpha-glucanotransferase 179 690 6.1E-112 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 hmeg3_RS11345 3b15a99a474ba73ef46f455b65960717 715 SUPERFAMILY SSF51445 633 701 4.83E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11345 3b15a99a474ba73ef46f455b65960717 715 SUPERFAMILY SSF51445 173 599 4.83E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS04015 7c4b12fa9a4533a55035f8ff6fe4dcd7 103 Gene3D G3DSA:3.40.30.10 2 103 3.6E-30 T 28-03-2018 hmeg3_RS04015 7c4b12fa9a4533a55035f8ff6fe4dcd7 103 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 1.3E-44 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related hmeg3_RS04015 7c4b12fa9a4533a55035f8ff6fe4dcd7 103 Pfam PF00462 Glutaredoxin 17 82 2.4E-18 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 hmeg3_RS04015 7c4b12fa9a4533a55035f8ff6fe4dcd7 103 SUPERFAMILY SSF52833 1 102 1.4E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS04015 7c4b12fa9a4533a55035f8ff6fe4dcd7 103 PIRSF PIRSF005894 1 103 5.3E-47 T 28-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.8E-45 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.712 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 SUPERFAMILY SSF55658 1 56 1.92E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 SUPERFAMILY SSF55653 60 148 1.7E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 Gene3D G3DSA:3.40.5.10 1 49 9.6E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 Gene3D G3DSA:3.10.430.100 63 147 6.3E-27 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 1.6E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.0E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08395 5c6d61c09a9c2b442cc16caa042a3417 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Pfam PF08335 GlnD PII-uridylyltransferase 161 299 5.1E-32 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 PIRSF PIRSF006288 1 850 0.0 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Pfam PF01909 Nucleotidyltransferase domain 51 102 2.9E-6 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 SUPERFAMILY SSF81593 180 283 3.06E-7 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Pfam PF01966 HD domain 436 538 6.7E-9 T 28-03-2018 IPR006674 HD domain hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Gene3D G3DSA:1.10.3090.10 325 614 3.5E-40 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 16 848 1.3E-243 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Gene3D G3DSA:3.30.70.260 778 848 3.2E-9 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Gene3D G3DSA:3.30.460.10 14 157 3.5E-28 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Gene3D G3DSA:1.20.120.330 159 304 3.9E-25 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 SUPERFAMILY SSF55021 669 732 1.3E-8 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 SUPERFAMILY SSF81301 37 146 5.18E-20 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Gene3D G3DSA:3.30.70.260 667 777 3.5E-7 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 SMART SM00471 431 578 6.6E-5 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 850 315.244 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 SUPERFAMILY SSF109604 402 525 6.91E-16 T 28-03-2018 hmeg3_RS09925 f1347391dec40246605e49abde8d8e7b 850 SUPERFAMILY SSF55021 778 830 7.4E-10 T 28-03-2018 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.399 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 8.1E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Gene3D G3DSA:3.40.50.300 75 205 2.0E-30 T 28-03-2018 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.6E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 SUPERFAMILY SSF50447 207 303 1.71E-27 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Pfam PF03144 Elongation factor Tu domain 2 227 295 2.0E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.6E-226 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Gene3D G3DSA:2.40.30.10 302 395 3.5E-32 T 28-03-2018 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 6.4E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Gene3D G3DSA:2.40.30.10 208 301 1.9E-28 T 28-03-2018 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 SUPERFAMILY SSF50465 304 396 2.88E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 Gene3D G3DSA:3.40.50.300 2 74 2.2E-10 T 28-03-2018 hmeg3_RS22870 0e96b154b1ab427782385e9e1719d45d 398 SUPERFAMILY SSF52540 5 221 9.26E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 Pfam PF03466 LysR substrate binding domain 92 293 3.7E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 Gene3D G3DSA:3.40.190.10 91 177 1.0E-11 T 28-03-2018 hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 7.5E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 SUPERFAMILY SSF53850 93 295 1.99E-38 T 28-03-2018 hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 Gene3D G3DSA:3.40.190.10 178 263 4.5E-20 T 28-03-2018 hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 SUPERFAMILY SSF46785 3 82 2.53E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04835 83246bb22b1294273c8356354799a587 296 Gene3D G3DSA:1.10.10.10 5 84 6.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 SUPERFAMILY SSF53850 100 301 9.59E-34 T 28-03-2018 hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 3.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 3.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 3.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 Gene3D G3DSA:1.10.10.10 1 94 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 SUPERFAMILY SSF46785 10 121 8.31E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 Gene3D G3DSA:3.40.190.10 102 186 2.9E-17 T 28-03-2018 hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 Gene3D G3DSA:3.40.190.10 187 268 1.1E-10 T 28-03-2018 hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 Pfam PF03466 LysR substrate binding domain 99 297 2.4E-30 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS14365 d522663161dd3657005dadf742ed8648 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 3.8E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01575 71eab7a1b3419b594e96b0721c4db162 182 Gene3D G3DSA:1.20.1290.10 43 167 3.6E-15 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS01575 71eab7a1b3419b594e96b0721c4db162 182 Pfam PF02627 Carboxymuconolactone decarboxylase family 49 101 5.0E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS01575 71eab7a1b3419b594e96b0721c4db162 182 SUPERFAMILY SSF69118 1 177 8.64E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS01575 71eab7a1b3419b594e96b0721c4db162 182 Gene3D G3DSA:1.20.5.810 10 42 5.2E-10 T 28-03-2018 hmeg3_RS01575 71eab7a1b3419b594e96b0721c4db162 182 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 99 7.0E-8 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS23310 73b4979e09a7732a20af76c0663c81c3 215 SUPERFAMILY SSF142695 18 187 5.23E-66 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 hmeg3_RS23310 73b4979e09a7732a20af76c0663c81c3 215 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 16 211 44.333 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 hmeg3_RS23310 73b4979e09a7732a20af76c0663c81c3 215 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 22 209 5.0E-77 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 hmeg3_RS23310 73b4979e09a7732a20af76c0663c81c3 215 Pfam PF00925 GTP cyclohydrolase II 23 185 3.2E-67 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 hmeg3_RS02560 143fab28476757157f5a9ace0a0b41d9 204 Gene3D G3DSA:1.10.4060.10 118 201 8.8E-17 T 28-03-2018 hmeg3_RS02560 143fab28476757157f5a9ace0a0b41d9 204 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 3 197 8.3E-22 T 28-03-2018 IPR003111 Lon, substrate-binding domain hmeg3_RS02560 143fab28476757157f5a9ace0a0b41d9 204 Gene3D G3DSA:2.30.130.40 1 114 2.0E-23 T 28-03-2018 hmeg3_RS02560 143fab28476757157f5a9ace0a0b41d9 204 SUPERFAMILY SSF88697 3 197 1.94E-51 T 28-03-2018 IPR015947 PUA-like domain hmeg3_RS02560 143fab28476757157f5a9ace0a0b41d9 204 SMART SM00464 3 199 1.1E-6 T 28-03-2018 IPR003111 Lon, substrate-binding domain hmeg3_RS05560 74ca42d24ce1e966263b51c5e71240d4 536 PIRSF PIRSF006429 4 534 4.6E-158 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein hmeg3_RS05560 74ca42d24ce1e966263b51c5e71240d4 536 Gene3D G3DSA:3.20.20.70 97 498 6.3E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS05560 74ca42d24ce1e966263b51c5e71240d4 536 Pfam PF01645 Conserved region in glutamate synthase 154 469 2.7E-83 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 hmeg3_RS05560 74ca42d24ce1e966263b51c5e71240d4 536 SUPERFAMILY SSF51395 19 491 7.33E-131 T 28-03-2018 hmeg3_RS05560 74ca42d24ce1e966263b51c5e71240d4 536 PIRSF PIRSF500060 9 527 5.1E-231 T 28-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 Gene3D G3DSA:1.20.1290.10 159 394 9.0E-34 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 SUPERFAMILY SSF69118 176 389 5.76E-37 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 Gene3D G3DSA:2.60.120.10 31 158 3.9E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 Pfam PF07883 Cupin domain 70 127 3.7E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 SUPERFAMILY SSF51182 45 158 9.78E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 Pfam PF02627 Carboxymuconolactone decarboxylase family 301 370 7.8E-8 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS20580 4bb0ad3154a3e90712aaf7c9b8c331e2 394 Pfam PF02627 Carboxymuconolactone decarboxylase family 180 244 5.2E-5 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS07945 9c73fac2c90bdeca2ed50b6e4fb437dc 259 SMART SM00382 29 209 8.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07945 9c73fac2c90bdeca2ed50b6e4fb437dc 259 SUPERFAMILY SSF52540 4 219 3.22E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07945 9c73fac2c90bdeca2ed50b6e4fb437dc 259 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS07945 9c73fac2c90bdeca2ed50b6e4fb437dc 259 Pfam PF00005 ABC transporter 20 160 4.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07945 9c73fac2c90bdeca2ed50b6e4fb437dc 259 Gene3D G3DSA:3.40.50.300 1 242 1.2E-49 T 28-03-2018 hmeg3_RS23180 81ec74a0e7b0100afa538d04488cd24c 769 Pfam PF00593 TonB dependent receptor 264 767 3.1E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23180 81ec74a0e7b0100afa538d04488cd24c 769 Gene3D G3DSA:2.170.130.10 53 189 1.2E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23180 81ec74a0e7b0100afa538d04488cd24c 769 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 767 5.8E-77 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS23180 81ec74a0e7b0100afa538d04488cd24c 769 SUPERFAMILY SSF56935 72 767 2.3E-115 T 28-03-2018 hmeg3_RS23180 81ec74a0e7b0100afa538d04488cd24c 769 Gene3D G3DSA:2.40.170.20 198 769 5.0E-78 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS23180 81ec74a0e7b0100afa538d04488cd24c 769 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 181 3.8E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS04945 5babb0c96856782d9fe5beb8ed85b20d 288 Pfam PF01040 UbiA prenyltransferase family 26 268 1.1E-59 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 hmeg3_RS04945 5babb0c96856782d9fe5beb8ed85b20d 288 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 3 286 27.49 T 28-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 hmeg3_RS04945 5babb0c96856782d9fe5beb8ed85b20d 288 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 9 285 2.1E-94 T 28-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 hmeg3_RS04945 5babb0c96856782d9fe5beb8ed85b20d 288 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 65 87 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site hmeg3_RS10560 abc2c75b1c7396d56389e27d3fe795d4 439 Gene3D G3DSA:3.40.50.2300 162 436 5.5E-23 T 28-03-2018 hmeg3_RS10560 abc2c75b1c7396d56389e27d3fe795d4 439 Pfam PF13458 Periplasmic binding protein 31 400 7.7E-73 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS10560 abc2c75b1c7396d56389e27d3fe795d4 439 SUPERFAMILY SSF53822 33 406 2.93E-51 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS10560 abc2c75b1c7396d56389e27d3fe795d4 439 Gene3D G3DSA:3.40.50.2300 33 161 7.9E-11 T 28-03-2018 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 SUPERFAMILY SSF46785 10 91 2.78E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 Gene3D G3DSA:3.40.190.10 101 187 5.7E-11 T 28-03-2018 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 Gene3D G3DSA:1.10.10.10 6 96 2.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 72 2.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 Pfam PF03466 LysR substrate binding domain 101 307 9.6E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 SUPERFAMILY SSF53850 101 309 4.16E-36 T 28-03-2018 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 Gene3D G3DSA:3.40.190.10 188 278 7.5E-25 T 28-03-2018 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 4.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 4.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23280 cd6e1556ee0d8fbbb1c3d266c8d4a0b4 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 4.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12525 f2958b55eae95a244baff49ae295f823 381 Pfam PF13458 Periplasmic binding protein 28 369 5.1E-58 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS12525 f2958b55eae95a244baff49ae295f823 381 Gene3D G3DSA:3.40.50.2300 202 357 3.2E-25 T 28-03-2018 hmeg3_RS12525 f2958b55eae95a244baff49ae295f823 381 Gene3D G3DSA:3.40.50.2300 20 201 3.6E-28 T 28-03-2018 hmeg3_RS12525 f2958b55eae95a244baff49ae295f823 381 SUPERFAMILY SSF53822 27 374 5.44E-79 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 Pfam PF01590 GAF domain 30 154 4.9E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 SUPERFAMILY SSF55073 165 314 5.1E-39 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 SMART SM00267 147 321 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 SUPERFAMILY SSF55781 30 154 3.71E-20 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 Gene3D G3DSA:3.30.450.40 23 175 3.4E-20 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 Pfam PF00990 Diguanylate cyclase, GGDEF domain 160 316 1.2E-40 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 Gene3D G3DSA:3.30.70.270 176 321 2.1E-45 T 28-03-2018 hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 159 315 1.2E-41 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20740 24e50d34c43aaa8acd553e4c2bc8a74f 338 SMART SM00065 26 164 3.6E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 SUPERFAMILY SSF53738 312 451 3.92E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 184 1.6E-33 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 SUPERFAMILY SSF55957 441 550 7.46E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 146 155 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Gene3D G3DSA:3.40.120.10 35 222 4.9E-42 T 28-03-2018 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 216 320 4.2E-14 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Gene3D G3DSA:3.40.120.10 332 449 3.8E-23 T 28-03-2018 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Gene3D G3DSA:3.40.120.10 223 331 3.2E-21 T 28-03-2018 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 327 445 9.9E-26 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Gene3D G3DSA:3.30.310.50 450 553 4.6E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 SUPERFAMILY SSF53738 215 322 4.88E-13 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 485 541 2.9E-7 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 3 550 5.0E-256 T 28-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 hmeg3_RS12485 a989c913e7142e5bd5caf7118acfec3d 555 SUPERFAMILY SSF53738 27 241 6.59E-45 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 SUPERFAMILY SSF143800 1 80 2.24E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 25.384 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 9.4E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 PRINTS PR01249 Ribosomal protein L31 signature 59 77 1.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 PRINTS PR01249 Ribosomal protein L31 signature 44 59 1.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS19640 30a93237aac29ee0f41bfb578d334a35 89 Pfam PF01197 Ribosomal protein L31 1 78 2.3E-31 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 4.6E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 Gene3D G3DSA:3.40.50.1360 64 237 2.6E-34 T 28-03-2018 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 SMART SM00420 6 58 2.7E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 SUPERFAMILY SSF46785 4 59 6.68E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 SUPERFAMILY SSF100950 76 230 1.88E-22 T 28-03-2018 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 Pfam PF00455 DeoR C terminal sensor domain 75 230 7.8E-41 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-10 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-10 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 SMART SM01134 71 232 1.5E-54 T 28-03-2018 hmeg3_RS12240 25179e89d978b5912df1f18e538dd804 251 Gene3D G3DSA:1.10.10.10 1 63 5.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04930 b9c08ec32b5da3ca5cf77aa3101920a3 232 Gene3D G3DSA:3.20.20.10 1 232 6.2E-72 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS04930 b9c08ec32b5da3ca5cf77aa3101920a3 232 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 230 1.1E-75 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein hmeg3_RS04930 b9c08ec32b5da3ca5cf77aa3101920a3 232 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein hmeg3_RS04930 b9c08ec32b5da3ca5cf77aa3101920a3 232 Pfam PF01168 Alanine racemase, N-terminal domain 17 230 1.7E-29 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS04930 b9c08ec32b5da3ca5cf77aa3101920a3 232 PIRSF PIRSF004848 1 232 3.0E-74 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein hmeg3_RS04930 b9c08ec32b5da3ca5cf77aa3101920a3 232 SUPERFAMILY SSF51419 1 228 1.96E-79 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 416 5.0E-124 T 28-03-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 Gene3D G3DSA:3.40.1060.10 149 272 6.5E-36 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 Pfam PF00330 Aconitase family (aconitate hydratase) 27 410 1.7E-78 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 SUPERFAMILY SSF53732 2 418 3.27E-111 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 Gene3D G3DSA:3.30.499.10 1 148 1.7E-22 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 PRINTS PR00415 Aconitase family signature 187 200 7.2E-11 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 PRINTS PR00415 Aconitase family signature 296 307 7.2E-11 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 PRINTS PR00415 Aconitase family signature 201 214 7.2E-11 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 PRINTS PR00415 Aconitase family signature 112 125 7.2E-11 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 PRINTS PR00415 Aconitase family signature 352 365 7.2E-11 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS20915 61fceccdcb4707f0fff50cbcaaeba519 424 Gene3D G3DSA:3.30.499.10 273 422 7.8E-46 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 216 1.5E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 SMART SM00862 146 217 5.8E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 Gene3D G3DSA:3.40.50.2300 1 121 1.4E-33 T 28-03-2018 hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 Gene3D G3DSA:1.10.10.10 122 220 5.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 SMART SM00448 1 112 5.9E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 SUPERFAMILY SSF52172 1 118 1.18E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11910 47c0e8b847fa59dbf93e11a066ae272c 221 SUPERFAMILY SSF46894 119 216 7.94E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 SUPERFAMILY SSF51735 1 216 2.14E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 Pfam PF00106 short chain dehydrogenase 6 194 7.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 Gene3D G3DSA:3.40.50.720 1 234 1.5E-48 T 28-03-2018 hmeg3_RS23920 d03a8f7b856f1abf0f0ce45b6ed67baa 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS00210 eedc2fac3fcafe367d79288fa2bb7103 141 SUPERFAMILY SSF54975 1 131 2.78E-37 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 hmeg3_RS00210 eedc2fac3fcafe367d79288fa2bb7103 141 Pfam PF04940 Sensors of blue-light using FAD 2 93 8.4E-29 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 hmeg3_RS00210 eedc2fac3fcafe367d79288fa2bb7103 141 SMART SM01034 2 94 2.3E-39 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 hmeg3_RS07995 e999ba5bf3922748795890189a61f54c 293 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 78 289 3.9E-74 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS07995 e999ba5bf3922748795890189a61f54c 293 SUPERFAMILY SSF56529 72 291 5.1E-74 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS07995 e999ba5bf3922748795890189a61f54c 293 Gene3D G3DSA:3.90.850.10 20 293 1.2E-79 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 Pfam PF00027 Cyclic nucleotide-binding domain 35 121 1.6E-17 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 Gene3D G3DSA:1.10.10.10 148 226 4.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 SUPERFAMILY SSF46785 153 225 7.92E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 SMART SM00100 16 137 7.4E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 8.2E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 Gene3D G3DSA:2.60.120.10 2 145 1.1E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 SUPERFAMILY SSF51206 10 144 5.24E-26 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like hmeg3_RS10535 363712e90508c285ba59edeb07ca75ba 227 SMART SM00419 170 218 1.7E-4 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 ProSitePatterns PS01244 Aconitase family signature 2. 494 507 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 Gene3D G3DSA:3.40.1060.10 237 369 1.3E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 Gene3D G3DSA:3.30.499.10 370 577 1.3E-62 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 895 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 Pfam PF00330 Aconitase family (aconitate hydratase) 70 563 7.2E-178 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 SUPERFAMILY SSF52016 638 895 2.16E-80 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 ProSitePatterns PS00450 Aconitase family signature 1. 428 444 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 Gene3D G3DSA:3.20.19.10 656 896 4.1E-87 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 SUPERFAMILY SSF53732 16 616 4.71E-213 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 494 507 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 276 289 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 370 384 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 432 443 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 171 179 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 200 213 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 290 303 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 214 229 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 PRINTS PR00415 Aconitase family signature 147 160 3.2E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 Gene3D G3DSA:3.30.499.10 29 236 2.1E-70 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS08725 57c32d1f59933e7bcb106f479a302c1a 897 Pfam PF00694 Aconitase C-terminal domain 695 820 3.5E-43 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS07785 21cc9c5aea04cde64d50bbd748025af5 131 SUPERFAMILY SSF46955 20 123 1.69E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS07785 21cc9c5aea04cde64d50bbd748025af5 131 SMART SM00422 22 92 2.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS07785 21cc9c5aea04cde64d50bbd748025af5 131 Gene3D G3DSA:1.10.1660.10 15 130 2.1E-27 T 28-03-2018 hmeg3_RS07785 21cc9c5aea04cde64d50bbd748025af5 131 Pfam PF13411 MerR HTH family regulatory protein 22 90 2.4E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS03895 819c6a2bdb6df24f5e5f59862fdb86b0 484 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 475 2.8E-96 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS03895 819c6a2bdb6df24f5e5f59862fdb86b0 484 Pfam PF02321 Outer membrane efflux protein 77 267 1.6E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS03895 819c6a2bdb6df24f5e5f59862fdb86b0 484 Pfam PF02321 Outer membrane efflux protein 296 475 2.3E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS03895 819c6a2bdb6df24f5e5f59862fdb86b0 484 Gene3D G3DSA:1.20.1600.10 23 482 2.1E-71 T 28-03-2018 hmeg3_RS03895 819c6a2bdb6df24f5e5f59862fdb86b0 484 SUPERFAMILY SSF56954 6 35 6.28E-85 T 28-03-2018 hmeg3_RS03895 819c6a2bdb6df24f5e5f59862fdb86b0 484 SUPERFAMILY SSF56954 68 477 6.28E-85 T 28-03-2018 hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 Pfam PF00271 Helicase conserved C-terminal domain 469 539 2.2E-6 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 TIGRFAM TIGR00595 priA: primosomal protein N' 163 678 2.5E-162 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 Pfam PF00270 DEAD/DEAH box helicase 145 311 1.7E-13 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 SUPERFAMILY SSF52540 445 564 7.14E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 SUPERFAMILY SSF52540 355 384 7.14E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 Gene3D G3DSA:3.40.50.300 140 311 2.5E-24 T 28-03-2018 hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 SUPERFAMILY SSF52540 140 321 3.98E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 SMART SM00487 138 342 3.9E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 680 22.206 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 SMART SM00490 442 539 5.3E-9 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS02485 2abcd980bb39759c64474afa16736886 680 Gene3D G3DSA:3.40.50.300 344 597 6.8E-19 T 28-03-2018 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 SUPERFAMILY SSF46626 31 130 3.02E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 PRINTS PR00604 Class IA and IB cytochrome C signature 103 113 2.0E-18 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 PRINTS PR00604 Class IA and IB cytochrome C signature 120 128 2.0E-18 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 PRINTS PR00604 Class IA and IB cytochrome C signature 43 50 2.0E-18 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 PRINTS PR00604 Class IA and IB cytochrome C signature 54 69 2.0E-18 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 PRINTS PR00604 Class IA and IB cytochrome C signature 70 80 2.0E-18 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 PRINTS PR00604 Class IA and IB cytochrome C signature 84 100 2.0E-18 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 Pfam PF00034 Cytochrome c 36 130 1.2E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03920 09185bcab00ebc6c17502becae1dfcd0 130 Gene3D G3DSA:1.10.760.10 5 130 7.4E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06535 64827bf0982f9fab05f49caabe4489d3 154 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 12 87 4.0E-27 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 hmeg3_RS06535 64827bf0982f9fab05f49caabe4489d3 154 Gene3D G3DSA:3.30.110.60 3 100 9.5E-20 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 hmeg3_RS06535 64827bf0982f9fab05f49caabe4489d3 154 SUPERFAMILY SSF75471 3 93 1.7E-25 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 hmeg3_RS06535 64827bf0982f9fab05f49caabe4489d3 154 Pfam PF01985 CRS1 / YhbY (CRM) domain 4 87 1.0E-14 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 hmeg3_RS06535 64827bf0982f9fab05f49caabe4489d3 154 SMART SM01103 4 87 3.4E-37 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Gene3D G3DSA:3.90.190.20 311 467 2.1E-36 T 28-03-2018 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 461 7.0E-161 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Gene3D G3DSA:3.40.1190.10 94 310 9.4E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Gene3D G3DSA:3.40.50.720 1 93 2.8E-16 T 28-03-2018 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Pfam PF01225 Mur ligase family, catalytic domain 8 105 5.6E-25 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Pfam PF08245 Mur ligase middle domain 110 290 1.1E-28 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 468 42.334 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 SUPERFAMILY SSF51984 6 92 1.1E-29 T 28-03-2018 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 406 2.3E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 SUPERFAMILY SSF53623 91 308 3.53E-70 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22005 60aeada4e99d528726399136a1c9ce74 474 SUPERFAMILY SSF53244 309 463 2.38E-43 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS06925 cd40ea9349eef52dd8ce9a41db1b16b4 193 Gene3D G3DSA:1.10.340.30 3 185 1.4E-77 T 28-03-2018 hmeg3_RS06925 cd40ea9349eef52dd8ce9a41db1b16b4 193 SUPERFAMILY SSF48150 4 186 1.41E-75 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 hmeg3_RS06925 cd40ea9349eef52dd8ce9a41db1b16b4 193 Pfam PF03352 Methyladenine glycosylase 8 184 1.8E-76 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 Gene3D G3DSA:3.40.50.300 1 256 5.0E-77 T 28-03-2018 hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 Pfam PF09383 NIL domain 262 334 2.3E-18 T 28-03-2018 IPR018449 NIL domain hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 SUPERFAMILY SSF52540 1 241 3.19E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 SMART SM00382 30 218 5.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 SMART SM00930 260 335 1.1E-19 T 28-03-2018 IPR018449 NIL domain hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 Pfam PF00005 ABC transporter 21 170 3.8E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 Gene3D G3DSA:3.30.70.260 257 336 3.8E-20 T 28-03-2018 hmeg3_RS09430 94cbae27591e64ac0a32e76c68e2a6ab 336 SUPERFAMILY SSF55021 259 335 1.37E-17 T 28-03-2018 hmeg3_RS09125 e9c338c18f06346d8ef7a3345b77733b 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 33 226 1.1E-7 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS09125 e9c338c18f06346d8ef7a3345b77733b 253 PIRSF PIRSF005917 1 251 4.1E-51 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS09125 e9c338c18f06346d8ef7a3345b77733b 253 Gene3D G3DSA:3.30.950.10 134 252 1.2E-24 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS09125 e9c338c18f06346d8ef7a3345b77733b 253 SUPERFAMILY SSF53790 3 251 2.09E-58 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS09125 e9c338c18f06346d8ef7a3345b77733b 253 Gene3D G3DSA:3.40.1010.10 2 133 2.9E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.30.450.20 513 544 0.012 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SMART SM00086 467 509 0.004 T 28-03-2018 IPR001610 PAC motif hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.40.50.2300 954 1095 2.0E-39 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:1.10.287.130 545 613 5.7E-18 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.30.565.10 614 782 3.8E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF47384 540 620 1.88E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF55785 406 516 3.7E-23 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF52172 795 924 4.27E-27 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.30.450.20 95 227 1.2E-39 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SMART SM00387 666 782 2.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:1.20.120.160 1121 1240 2.9E-11 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 392 516 2.7E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF00512 His Kinase A (phospho-acceptor) domain 554 619 4.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF47226 1066 1079 2.09E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF47226 1129 1212 2.09E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF00072 Response regulator receiver domain 970 1083 7.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF00072 Response regulator receiver domain 798 916 2.9E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 PRINTS PR00344 Bacterial sensor protein C-terminal signature 742 760 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 PRINTS PR00344 Bacterial sensor protein C-terminal signature 766 779 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 PRINTS PR00344 Bacterial sensor protein C-terminal signature 707 721 1.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF52172 966 1090 8.97E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF103190 59 228 2.22E-47 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SMART SM00448 968 1083 9.2E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SMART SM00448 796 916 3.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.30.450.20 236 328 2.7E-22 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SMART SM00091 395 461 8.3E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF01627 Hpt domain 1150 1212 6.0E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF55874 608 784 3.01E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.30.450.20 370 512 1.3E-23 T 28-03-2018 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 666 781 4.3E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SUPERFAMILY SSF103190 237 327 5.49E-17 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF00989 PAS fold 398 506 8.9E-14 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Pfam PF02743 Cache domain 96 319 4.8E-14 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 SMART SM00388 554 619 5.0E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23495 46e5050b7cf35b32769ab27c66b1c193 1243 Gene3D G3DSA:3.40.50.2300 783 935 2.8E-28 T 28-03-2018 hmeg3_RS22750 50dc1b57a49884c36ae6834a4c1691e6 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 3.0E-8 T 28-03-2018 hmeg3_RS22750 50dc1b57a49884c36ae6834a4c1691e6 37 Pfam PF00444 Ribosomal protein L36 1 37 6.6E-18 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22750 50dc1b57a49884c36ae6834a4c1691e6 37 SUPERFAMILY SSF57840 1 37 3.27E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22750 50dc1b57a49884c36ae6834a4c1691e6 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.842 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22750 50dc1b57a49884c36ae6834a4c1691e6 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22750 50dc1b57a49884c36ae6834a4c1691e6 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.6E-21 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 Gene3D G3DSA:3.30.70.920 53 151 1.2E-26 T 28-03-2018 hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 SMART SM00344 1 110 1.6E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 Gene3D G3DSA:1.10.10.10 1 52 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 SUPERFAMILY SSF54909 61 150 9.39E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 Pfam PF01037 Lrp/AsnC ligand binding domain 69 141 4.4E-23 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 SUPERFAMILY SSF46785 1 60 1.28E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14355 9222f191db75a9ee08abd968a3d3826c 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 5.9E-17 T 28-03-2018 hmeg3_RS13230 0fb7e91db96ace9138ddcda65a52a62d 438 Gene3D G3DSA:1.20.1250.20 16 225 1.2E-33 T 28-03-2018 hmeg3_RS13230 0fb7e91db96ace9138ddcda65a52a62d 438 Pfam PF07690 Major Facilitator Superfamily 33 395 1.8E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS13230 0fb7e91db96ace9138ddcda65a52a62d 438 Gene3D G3DSA:1.20.1250.20 240 438 6.5E-24 T 28-03-2018 hmeg3_RS13230 0fb7e91db96ace9138ddcda65a52a62d 438 SUPERFAMILY SSF103473 20 430 3.4E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04950 d34272e66b442c2f55e3687717415a62 435 Gene3D G3DSA:3.40.190.10 159 359 1.8E-41 T 28-03-2018 hmeg3_RS04950 d34272e66b442c2f55e3687717415a62 435 SUPERFAMILY SSF53850 26 423 9.83E-76 T 28-03-2018 hmeg3_RS04950 d34272e66b442c2f55e3687717415a62 435 Pfam PF13416 Bacterial extracellular solute-binding protein 44 359 1.2E-44 T 28-03-2018 hmeg3_RS04950 d34272e66b442c2f55e3687717415a62 435 Gene3D G3DSA:3.40.190.10 25 158 1.5E-12 T 28-03-2018 hmeg3_RS08845 534016d871d9f6b38ef8fdeb18643042 230 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 21 222 2.8E-45 T 28-03-2018 IPR006214 Bax inhibitor 1-related hmeg3_RS10965 8d8cbc0f94649c1cb5eb6e1d12e3f5df 304 Gene3D G3DSA:1.20.58.370 9 52 6.7E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain hmeg3_RS10965 8d8cbc0f94649c1cb5eb6e1d12e3f5df 304 Gene3D G3DSA:1.10.3720.10 71 302 5.0E-44 T 28-03-2018 hmeg3_RS10965 8d8cbc0f94649c1cb5eb6e1d12e3f5df 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 301 3.0E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10965 8d8cbc0f94649c1cb5eb6e1d12e3f5df 304 SUPERFAMILY SSF161098 65 289 2.88E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS22805 0e9d615324fe5d0303f25c2e7e9533d2 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 102 1.0E-31 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22805 0e9d615324fe5d0303f25c2e7e9533d2 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 103 17.299 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22805 0e9d615324fe5d0303f25c2e7e9533d2 104 Gene3D G3DSA:2.30.30.30 2 92 7.6E-26 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 hmeg3_RS22805 0e9d615324fe5d0303f25c2e7e9533d2 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22805 0e9d615324fe5d0303f25c2e7e9533d2 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 9.9E-21 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22805 0e9d615324fe5d0303f25c2e7e9533d2 104 SUPERFAMILY SSF50104 3 101 1.42E-29 T 28-03-2018 IPR008991 Translation protein SH3-like domain hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 SUPERFAMILY SSF103473 17 426 1.57E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 Gene3D G3DSA:1.20.1250.20 229 431 4.4E-21 T 28-03-2018 hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 Pfam PF07690 Major Facilitator Superfamily 30 386 1.5E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 98 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS22405 58efb2a33b07912402e06dbb205d1a80 433 Gene3D G3DSA:1.20.1250.20 18 228 3.5E-25 T 28-03-2018 hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 SMART SM00346 21 109 1.2E-25 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 SUPERFAMILY SSF55781 85 264 4.25E-44 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 Gene3D G3DSA:3.30.450.40 85 264 2.7E-47 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 18 263 6.5E-93 T 28-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 SUPERFAMILY SSF46785 23 92 1.03E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 Pfam PF01614 Bacterial transcriptional regulator 139 253 2.3E-32 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 Gene3D G3DSA:1.10.10.10 21 80 1.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01245 e1754874c017c15e30342d757ae83c9a 264 Pfam PF09339 IclR helix-turn-helix domain 24 72 9.5E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 1.6E-18 T 28-03-2018 hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 SMART SM00344 7 116 1.0E-39 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 SUPERFAMILY SSF46785 7 66 4.92E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 Gene3D G3DSA:3.30.70.920 57 154 1.3E-15 T 28-03-2018 hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 SUPERFAMILY SSF54909 68 149 2.95E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 3.0E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 Gene3D G3DSA:1.10.10.10 7 56 6.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.1E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.1E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03805 04b1b989dfff409f3e3ed03e2a7d5728 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.1E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS10590 d012a49cde39ba6260461e5c56f65271 210 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 34 193 2.1E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain hmeg3_RS10590 d012a49cde39ba6260461e5c56f65271 210 Gene3D G3DSA:3.40.50.1110 28 210 5.2E-37 T 28-03-2018 hmeg3_RS10590 d012a49cde39ba6260461e5c56f65271 210 SUPERFAMILY SSF52266 29 209 7.79E-47 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 Gene3D G3DSA:1.10.275.10 1 116 2.1E-40 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 Pfam PF00206 Lyase 14 312 1.1E-64 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 452 6.3E-133 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 SUPERFAMILY SSF48557 4 446 8.64E-109 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 1.3E-18 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 1.3E-18 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 PRINTS PR00149 Fumarate lyase superfamily signature 116 134 1.3E-18 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 1.3E-18 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 Gene3D G3DSA:1.20.200.10 117 390 3.0E-87 T 28-03-2018 hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 Gene3D G3DSA:1.10.40.30 391 445 1.1E-31 T 28-03-2018 hmeg3_RS20005 e04bbe72a2cf5b75ea9d16399d26bb20 455 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 2.6E-52 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 Pfam PF06745 KaiC 21 245 3.6E-41 T 28-03-2018 IPR014774 KaiC-like domain hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 Pfam PF06745 KaiC 260 479 2.7E-23 T 28-03-2018 IPR014774 KaiC-like domain hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 SUPERFAMILY SSF52540 19 248 5.21E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 PIRSF PIRSF039117 5 501 1.6E-115 T 28-03-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 SUPERFAMILY SSF52540 259 490 2.19E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 Gene3D G3DSA:3.40.50.300 258 481 1.8E-34 T 28-03-2018 hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 Gene3D G3DSA:3.40.50.300 19 252 3.0E-37 T 28-03-2018 hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 SMART SM00382 37 206 1.2 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 SMART SM00382 277 440 0.026 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 PRINTS PR01874 DNA repair protein radA signature 269 297 2.8E-9 T 28-03-2018 hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 PRINTS PR01874 DNA repair protein radA signature 311 328 2.8E-9 T 28-03-2018 hmeg3_RS11285 1a45426e9cccb3a133341f62d4d51ec6 505 PRINTS PR01874 DNA repair protein radA signature 410 438 2.8E-9 T 28-03-2018 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 SUPERFAMILY SSF48179 159 268 2.04E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 96 9.4E-18 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 264 26.505 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 264 1.3E-77 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 Gene3D G3DSA:1.10.3730.10 162 269 2.3E-35 T 28-03-2018 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 SUPERFAMILY SSF51735 3 157 1.51E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 PIRSF PIRSF000193 1 267 1.8E-73 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 Gene3D G3DSA:3.40.50.720 1 161 3.2E-31 T 28-03-2018 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 219 242 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 hmeg3_RS04935 68e74feeb438e6b1ba94c666266ff325 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 5.8E-32 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 hmeg3_RS20540 80fe30a5fcf4634d8b08e2dc235d3748 429 PIRSF PIRSF002808 1 428 2.0E-38 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 hmeg3_RS20540 80fe30a5fcf4634d8b08e2dc235d3748 429 SUPERFAMILY SSF103473 7 420 9.42E-84 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS20540 80fe30a5fcf4634d8b08e2dc235d3748 429 Gene3D G3DSA:1.20.1250.20 218 421 5.8E-29 T 28-03-2018 hmeg3_RS20540 80fe30a5fcf4634d8b08e2dc235d3748 429 Pfam PF07690 Major Facilitator Superfamily 20 383 2.0E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS20540 80fe30a5fcf4634d8b08e2dc235d3748 429 Gene3D G3DSA:1.20.1250.20 4 203 3.8E-36 T 28-03-2018 hmeg3_RS14045 d6681353532fbcdcca9c75f00ad21bd1 112 SUPERFAMILY SSF117782 58 111 1.7E-7 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 hmeg3_RS14045 d6681353532fbcdcca9c75f00ad21bd1 112 Pfam PF01906 Putative heavy-metal-binding 64 109 1.6E-5 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 PRINTS PR00095 Anthranilate synthase component I signature 346 359 7.3E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 PRINTS PR00095 Anthranilate synthase component I signature 332 345 7.3E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 PRINTS PR00095 Anthranilate synthase component I signature 441 455 7.3E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 PRINTS PR00095 Anthranilate synthase component I signature 426 440 7.3E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 SUPERFAMILY SSF56322 14 492 1.83E-150 T 28-03-2018 IPR005801 ADC synthase GO:0009058 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 Gene3D G3DSA:3.60.120.10 13 494 3.5E-159 T 28-03-2018 IPR005801 ADC synthase GO:0009058 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 Pfam PF00425 chorismate binding enzyme 221 484 8.3E-92 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 492 1.6E-163 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04450 f53c1433f36538441b2ea838ac554ebd 503 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 172 1.4E-33 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04315 f32945ba0bbd0ee78694d2dfa1369a69 209 Gene3D G3DSA:2.50.20.10 30 209 2.0E-32 T 28-03-2018 hmeg3_RS04315 f32945ba0bbd0ee78694d2dfa1369a69 209 Pfam PF03550 Outer membrane lipoprotein LolB 44 206 3.5E-36 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 hmeg3_RS04315 f32945ba0bbd0ee78694d2dfa1369a69 209 SUPERFAMILY SSF89392 20 207 5.89E-32 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX hmeg3_RS03660 1729fee371891edf58d60ae0e34f5558 359 SMART SM00729 115 322 2.7E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS03660 1729fee371891edf58d60ae0e34f5558 359 SUPERFAMILY SSF102114 99 323 5.76E-28 T 28-03-2018 hmeg3_RS03660 1729fee371891edf58d60ae0e34f5558 359 TIGRFAM TIGR04043 rSAM_MSMEG_0568: radical SAM protein, MSMEG_0568 family 2 355 4.9E-182 T 28-03-2018 IPR016779 Radical SAM enzyme, MSMEG0568 hmeg3_RS03660 1729fee371891edf58d60ae0e34f5558 359 Gene3D G3DSA:3.20.20.70 115 355 8.9E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS03660 1729fee371891edf58d60ae0e34f5558 359 Pfam PF04055 Radical SAM superfamily 125 282 9.1E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS03660 1729fee371891edf58d60ae0e34f5558 359 PIRSF PIRSF020870 1 356 9.7E-173 T 28-03-2018 IPR016779 Radical SAM enzyme, MSMEG0568 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 759 805 2.7E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 809 853 2.5E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 703 9.1E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 708 753 1.8E-14 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 599 649 2.4E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 594 1.6E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Gene3D G3DSA:2.120.10.90 544 873 5.4E-130 T 28-03-2018 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Gene3D G3DSA:3.90.199.10 286 375 2.6E-10 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 SUPERFAMILY SSF101904 544 865 1.31E-108 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 SUPERFAMILY SSF56719 30 522 8.5E-178 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Gene3D G3DSA:1.10.268.10 376 504 8.7E-49 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Gene3D G3DSA:3.90.199.10 34 285 5.7E-116 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 513 3.0E-155 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 SMART SM00434 11 506 4.6E-285 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 857 23.856 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 hmeg3_RS18000 f0e8e33ed5359f68323cff1228e123ac 890 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 856 0.0 T 28-03-2018 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 Pfam PF07730 Histidine kinase 475 539 1.6E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 Gene3D G3DSA:3.30.450.20 441 480 0.045 T 28-03-2018 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 442 4.6E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 Gene3D G3DSA:3.30.565.10 538 677 3.0E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 SUPERFAMILY SSF55785 333 445 1.39E-15 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 SUPERFAMILY SSF55874 534 672 4.06E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 SMART SM00387 579 673 1.0E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 Gene3D G3DSA:3.30.450.20 307 440 1.1E-24 T 28-03-2018 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 629 3.1E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 657 670 3.1E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 Pfam PF08448 PAS fold 329 438 2.1E-15 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 581 671 1.7E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18220 d4f1a498bfc4e68c4abf3a1b18bdc813 690 SMART SM00091 322 389 0.0016 T 28-03-2018 IPR000014 PAS domain hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 SMART SM00345 34 93 4.0E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 1.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 1.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 Gene3D G3DSA:1.20.120.530 99 258 2.7E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 SMART SM00895 117 243 1.8E-17 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 Gene3D G3DSA:1.10.10.10 24 95 5.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 SUPERFAMILY SSF48008 115 248 4.18E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 Pfam PF07729 FCD domain 118 242 4.0E-21 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 93 6.8E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15110 c9cfadafbe1193f7a33b15ef8ab600a4 274 SUPERFAMILY SSF46785 27 97 5.75E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 Pfam PF01584 CheW-like domain 686 827 7.6E-21 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 SUPERFAMILY SSF50341 678 828 3.66E-21 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 Gene3D G3DSA:3.30.450.20 91 209 5.1E-9 T 28-03-2018 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 Gene3D G3DSA:3.30.450.20 422 554 3.3E-12 T 28-03-2018 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 Pfam PF02743 Cache domain 401 616 6.3E-13 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 SMART SM00260 681 825 1.0E-12 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 Gene3D G3DSA:2.30.30.40 772 818 5.8E-7 T 28-03-2018 hmeg3_RS23465 efd76cceae71c437ac008553026a4bcd 853 Gene3D G3DSA:2.40.50.180 702 771 9.4E-12 T 28-03-2018 hmeg3_RS17810 8cec2ea2a023d9dad6ead8579b950b06 378 SUPERFAMILY SSF53822 24 372 6.75E-91 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS17810 8cec2ea2a023d9dad6ead8579b950b06 378 Gene3D G3DSA:3.40.50.2300 22 358 7.4E-68 T 28-03-2018 hmeg3_RS17810 8cec2ea2a023d9dad6ead8579b950b06 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 5.1E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS17810 8cec2ea2a023d9dad6ead8579b950b06 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 5.1E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS17810 8cec2ea2a023d9dad6ead8579b950b06 378 Pfam PF13458 Periplasmic binding protein 26 369 1.3E-57 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS19690 f091bb462b80c0ead07b38add855b555 165 SUPERFAMILY SSF46767 76 162 1.83E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS19690 f091bb462b80c0ead07b38add855b555 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 160 3.6E-23 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS19690 f091bb462b80c0ead07b38add855b555 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 78 162 7.6E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS19690 f091bb462b80c0ead07b38add855b555 165 SUPERFAMILY SSF53155 11 82 7.45E-5 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS19690 f091bb462b80c0ead07b38add855b555 165 Gene3D G3DSA:1.10.10.10 70 163 5.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 SMART SM00387 336 442 3.1E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 284 1.2E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 439 6.2E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 6.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 6.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 439 6.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 6.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 Gene3D G3DSA:3.30.565.10 289 443 1.9E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 SUPERFAMILY SSF55874 292 439 1.14E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 Gene3D G3DSA:1.10.287.130 209 285 3.8E-10 T 28-03-2018 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 SUPERFAMILY SSF47384 215 285 1.26E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS01730 a268f1f3d87fbbedc8ecf2fcb1da4f4c 443 SMART SM00388 221 289 8.5E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 Pfam PF00106 short chain dehydrogenase 7 203 3.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 0.0041 T 28-03-2018 hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 4.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 4.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 SUPERFAMILY SSF51735 3 248 9.29E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01115 b058675982eb33d449471043cdf64de2 254 Gene3D G3DSA:3.40.50.720 1 252 1.2E-58 T 28-03-2018 hmeg3_RS15950 0dda6d1ce2ee74f9cd94250cf06df37f 391 Pfam PF08378 Nuclease-related domain 20 136 8.4E-10 T 28-03-2018 IPR011528 Nuclease-related domain, NERD hmeg3_RS15035 da96ec98b8598ece56080ee73c7f6562 71 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 26 4.6E-14 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 hmeg3_RS15035 da96ec98b8598ece56080ee73c7f6562 71 Pfam PF08173 Membrane bound YbgT-like protein 1 26 1.2E-14 T 28-03-2018 IPR012994 Membrane bound YbgT-like hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 Gene3D G3DSA:3.40.50.300 1 305 5.4E-51 T 28-03-2018 hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 Gene3D G3DSA:3.40.50.300 306 408 7.0E-18 T 28-03-2018 hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 Gene3D G3DSA:3.40.50.300 446 650 3.2E-29 T 28-03-2018 hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 SUPERFAMILY SSF52540 4 633 1.18E-127 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 Pfam PF00580 UvrD/REP helicase N-terminal domain 31 294 6.4E-54 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 Pfam PF13361 UvrD-like helicase C-terminal domain 562 623 4.0E-17 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS11130 cf6c11a0a701297fc87aded491e935e9 691 Pfam PF13361 UvrD-like helicase C-terminal domain 302 454 9.3E-22 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 SUPERFAMILY SSF52540 4 243 1.64E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 Gene3D G3DSA:2.40.50.140 301 364 7.0E-12 T 28-03-2018 hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 SMART SM00382 29 212 6.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 Gene3D G3DSA:2.40.50.100 240 300 5.6E-13 T 28-03-2018 hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 Pfam PF00005 ABC transporter 20 162 4.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 Gene3D G3DSA:3.40.50.300 1 238 5.6E-72 T 28-03-2018 hmeg3_RS19090 0dcc752caab8cc4a4615cfab3258deb2 380 SUPERFAMILY SSF50331 237 379 5.59E-23 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS07360 3005dceac53200ea1a773b9f57dfb6c2 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 24 152 1.6E-32 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 hmeg3_RS07360 3005dceac53200ea1a773b9f57dfb6c2 160 SUPERFAMILY SSF55961 16 157 2.36E-43 T 28-03-2018 hmeg3_RS07360 3005dceac53200ea1a773b9f57dfb6c2 160 Gene3D G3DSA:3.30.530.20 8 160 7.9E-31 T 28-03-2018 IPR023393 START-like domain hmeg3_RS20115 ed9a41e9e1520c68b34c57a42d6ca96a 316 Gene3D G3DSA:3.40.50.1820 35 313 1.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20115 ed9a41e9e1520c68b34c57a42d6ca96a 316 SUPERFAMILY SSF53474 20 295 3.21E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20115 ed9a41e9e1520c68b34c57a42d6ca96a 316 Pfam PF00561 alpha/beta hydrolase fold 55 292 4.7E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS20115 ed9a41e9e1520c68b34c57a42d6ca96a 316 PIRSF PIRSF005211 1 316 8.8E-95 T 28-03-2018 IPR012020 AB hydrolase 4 family hmeg3_RS00985 77899b14ecd686fbfd8d63281818bd34 312 SMART SM01130 11 304 4.0E-62 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS00985 77899b14ecd686fbfd8d63281818bd34 312 Pfam PF00701 Dihydrodipicolinate synthetase family 13 297 1.4E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS00985 77899b14ecd686fbfd8d63281818bd34 312 Gene3D G3DSA:3.20.20.70 6 309 5.4E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS00985 77899b14ecd686fbfd8d63281818bd34 312 SUPERFAMILY SSF51569 9 306 3.45E-67 T 28-03-2018 hmeg3_RS00985 77899b14ecd686fbfd8d63281818bd34 312 PIRSF PIRSF001365 8 311 1.4E-51 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS11590 fb27b13fb7b1136e874e8dd6eb362190 475 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 201 256 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11590 fb27b13fb7b1136e874e8dd6eb362190 475 SUPERFAMILY SSF81442 7 465 2.62E-121 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11590 fb27b13fb7b1136e874e8dd6eb362190 475 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 6 471 2.3E-233 T 28-03-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 hmeg3_RS11590 fb27b13fb7b1136e874e8dd6eb362190 475 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 10 441 5.1E-117 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11590 fb27b13fb7b1136e874e8dd6eb362190 475 Gene3D G3DSA:1.20.210.10 2 470 7.0E-96 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS12235 f4e3235556fc6b8419dd8b1728b471fc 196 Gene3D G3DSA:3.90.79.10 1 193 3.9E-34 T 28-03-2018 hmeg3_RS12235 f4e3235556fc6b8419dd8b1728b471fc 196 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 8 188 1.6E-45 T 28-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 hmeg3_RS12235 f4e3235556fc6b8419dd8b1728b471fc 196 SUPERFAMILY SSF55811 11 190 4.62E-44 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS12235 f4e3235556fc6b8419dd8b1728b471fc 196 Pfam PF00293 NUDIX domain 46 171 4.0E-7 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS08550 a024e004a8be598567b9e39817b806f2 134 SUPERFAMILY SSF51182 14 116 5.45E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS08550 a024e004a8be598567b9e39817b806f2 134 Pfam PF07883 Cupin domain 42 113 8.6E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS08550 a024e004a8be598567b9e39817b806f2 134 Gene3D G3DSA:2.60.120.10 1 129 2.3E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS18815 0bf9a8b2a144b3426cfc0b56bbd07132 286 SUPERFAMILY SSF50182 106 170 5.56E-17 T 28-03-2018 IPR010920 LSM domain hmeg3_RS18815 0bf9a8b2a144b3426cfc0b56bbd07132 286 Gene3D G3DSA:3.30.70.100 174 257 8.8E-12 T 28-03-2018 hmeg3_RS18815 0bf9a8b2a144b3426cfc0b56bbd07132 286 SUPERFAMILY SSF82861 20 103 1.7E-12 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 hmeg3_RS18815 0bf9a8b2a144b3426cfc0b56bbd07132 286 Gene3D G3DSA:2.30.30.60 121 170 5.5E-16 T 28-03-2018 hmeg3_RS18815 0bf9a8b2a144b3426cfc0b56bbd07132 286 SUPERFAMILY SSF82689 174 262 5.62E-17 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 hmeg3_RS18815 0bf9a8b2a144b3426cfc0b56bbd07132 286 Pfam PF00924 Mechanosensitive ion channel 65 257 5.2E-40 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 4.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 4.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 4.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 4.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 4.3E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 695 3.5E-16 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Gene3D G3DSA:1.20.58.130 708 799 4.5E-5 T 28-03-2018 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 SUPERFAMILY SSF50447 454 552 3.88E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 SMART SM00863 653 695 6.1E-19 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Pfam PF02272 DHHA1 domain 733 870 1.7E-28 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 SUPERFAMILY SSF101353 257 446 1.83E-59 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Gene3D G3DSA:3.30.930.10 1 253 4.4E-113 T 28-03-2018 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 SUPERFAMILY SSF55186 552 706 5.76E-49 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 SUPERFAMILY SSF55681 2 256 1.17E-104 T 28-03-2018 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 853 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Gene3D G3DSA:3.30.980.10 553 707 1.3E-42 T 28-03-2018 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 201.635 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 hmeg3_RS05545 ed4c20d2b5810f860dcabb2096262143 874 Pfam PF01411 tRNA synthetases class II (A) 5 555 3.5E-218 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 Gene3D G3DSA:1.20.1260.10 1 78 2.0E-18 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 Pfam PF00210 Ferritin-like domain 8 143 7.8E-41 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 SUPERFAMILY SSF47240 1 154 3.42E-55 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 1.3E-72 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 Gene3D G3DSA:1.20.5.420 85 138 1.2E-23 T 28-03-2018 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 44 64 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 65 85 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 86 106 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 107 127 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 3 22 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 23 43 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PRINTS PR00601 Bacterioferritin signature 128 149 4.6E-66 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS19995 f80140e187f2aaf63a7b4d27ee84bb5d 157 PIRSF PIRSF002560 1 157 9.7E-73 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 SMART SM01091 352 432 2.7E-22 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 Pfam PF03471 Transporter associated domain 353 430 3.1E-18 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 Gene3D G3DSA:3.20.20.70 158 358 7.2E-19 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 Gene3D G3DSA:3.30.465.10 359 441 4.2E-20 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 Pfam PF01595 Domain of unknown function DUF21 11 202 5.7E-37 T 28-03-2018 IPR002550 Domain of unknown function DUF21 hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 Pfam PF00571 CBS domain 291 338 8.7E-5 T 28-03-2018 IPR000644 CBS domain hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 SUPERFAMILY SSF56176 350 434 5.18E-20 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS14115 04171eb96ac28fbab86cae12e09cc4b1 441 SUPERFAMILY SSF54631 204 340 2.71E-20 T 28-03-2018 hmeg3_RS11460 980ec90c400e7e8f8be09980f8d93018 190 Pfam PF09361 Phasin protein 24 109 8.1E-5 T 28-03-2018 IPR018968 Phasin hmeg3_RS16840 eb68beb26b43bcc5a4fbfb641c5097c2 103 Pfam PF11720 Peptidase inhibitor I78 family 39 103 5.0E-13 T 28-03-2018 IPR021719 Proteinase inhibitor I78 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 168 368 7.5E-37 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 SUPERFAMILY SSF50022 4 144 1.22E-34 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 1.5E-5 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 1.5E-5 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 SUPERFAMILY SSF55961 164 365 3.3E-41 T 28-03-2018 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 Pfam PF00355 Rieske [2Fe-2S] domain 53 121 3.9E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 Gene3D G3DSA:3.90.380.10 125 375 2.8E-38 T 28-03-2018 hmeg3_RS04800 38ecc381085bb4212d3fd4841b6c00f4 375 Gene3D G3DSA:2.20.25.10 79 124 1.6E-18 T 28-03-2018 hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 Gene3D G3DSA:1.20.200.10 103 370 3.6E-69 T 28-03-2018 hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 1.6E-15 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 PRINTS PR00149 Fumarate lyase superfamily signature 100 118 1.6E-15 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 PRINTS PR00149 Fumarate lyase superfamily signature 230 257 1.6E-15 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 PRINTS PR00149 Fumarate lyase superfamily signature 145 163 1.6E-15 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 Pfam PF00206 Lyase 11 290 4.1E-40 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 SUPERFAMILY SSF48557 6 447 2.04E-93 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 SMART SM00998 363 446 8.5E-14 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 Gene3D G3DSA:1.10.275.10 1 102 5.7E-12 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 Gene3D G3DSA:1.10.40.30 371 446 5.6E-16 T 28-03-2018 hmeg3_RS01230 1d098eac7913384ad4214b84296396e6 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 364 444 2.1E-12 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 Gene3D G3DSA:3.40.309.10 277 468 1.4E-75 T 28-03-2018 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 SUPERFAMILY SSF53720 7 485 1.57E-174 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 Pfam PF00171 Aldehyde dehydrogenase family 23 480 1.5E-170 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 34 480 7.1E-229 T 28-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 hmeg3_RS12030 10e6affa6a1f15844762a1e83ce2d9b6 487 Gene3D G3DSA:3.40.605.10 11 276 5.6E-102 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS11070 981ec963d9a22d6054b9944dba97653c 385 Gene3D G3DSA:3.90.1150.10 269 382 6.4E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS11070 981ec963d9a22d6054b9944dba97653c 385 Gene3D G3DSA:3.40.640.10 13 262 4.1E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS11070 981ec963d9a22d6054b9944dba97653c 385 Pfam PF00266 Aminotransferase class-V 5 368 5.2E-81 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS11070 981ec963d9a22d6054b9944dba97653c 385 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site hmeg3_RS11070 981ec963d9a22d6054b9944dba97653c 385 PIRSF PIRSF005572 2 382 1.6E-124 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 hmeg3_RS11070 981ec963d9a22d6054b9944dba97653c 385 SUPERFAMILY SSF53383 4 378 2.13E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 SUPERFAMILY SSF52540 310 527 5.55E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 Gene3D G3DSA:3.40.50.300 312 660 2.1E-48 T 28-03-2018 hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 Pfam PF00005 ABC transporter 17 182 2.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 Pfam PF00005 ABC transporter 344 473 2.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 Gene3D G3DSA:3.40.50.300 1 303 1.0E-52 T 28-03-2018 hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 SMART SM00382 351 518 2.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 SMART SM00382 26 228 3.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 SUPERFAMILY SSF52540 2 92 2.89E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 SUPERFAMILY SSF52540 123 253 2.89E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 Pfam PF12848 ABC transporter 221 303 6.3E-24 T 28-03-2018 IPR032781 ABC-transporter extension domain hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09840 0cb8828b2c43aebee4c60bf211d8aadd 669 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS07740 ea7cd3873e3ef6dfed67f80aa54a9ff7 255 SUPERFAMILY SSF56529 8 252 1.34E-35 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS07740 ea7cd3873e3ef6dfed67f80aa54a9ff7 255 Gene3D G3DSA:3.90.850.10 4 255 6.5E-21 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Pfam PF00072 Response regulator receiver domain 635 749 5.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 SUPERFAMILY SSF47384 341 418 3.14E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 SUPERFAMILY SSF55874 406 582 1.44E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Pfam PF00512 His Kinase A (phospho-acceptor) domain 352 417 2.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Gene3D G3DSA:3.30.450.20 67 203 9.9E-13 T 28-03-2018 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Gene3D G3DSA:1.10.287.130 342 413 6.0E-19 T 28-03-2018 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 SMART SM00448 633 749 5.9E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 SUPERFAMILY SSF52172 634 756 1.21E-40 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 SMART SM00387 464 582 1.8E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Gene3D G3DSA:3.30.565.10 421 590 1.2E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 SMART SM00388 352 417 3.5E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Gene3D G3DSA:3.40.50.2300 629 763 1.5E-43 T 28-03-2018 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 579 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 560 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 1.0E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 466 580 2.3E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11520 9480cc72635f6506278096662812bbf8 764 Pfam PF02743 Cache domain 56 242 5.5E-13 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS24500 576bf9b9a6fdf757bc1ed0599ac891c2 244 SUPERFAMILY SSF161098 23 221 7.19E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24500 576bf9b9a6fdf757bc1ed0599ac891c2 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 235 5.8E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24500 576bf9b9a6fdf757bc1ed0599ac891c2 244 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 130 2.6E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS24500 576bf9b9a6fdf757bc1ed0599ac891c2 244 Gene3D G3DSA:1.10.3720.10 17 236 7.6E-40 T 28-03-2018 hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 Pfam PF07729 FCD domain 98 224 4.4E-25 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.9E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.9E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 Gene3D G3DSA:1.10.10.10 6 80 3.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 SUPERFAMILY SSF46785 11 104 1.91E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 SMART SM00345 19 78 1.3E-24 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 SMART SM00895 98 224 3.3E-22 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 SUPERFAMILY SSF48008 96 232 1.12E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 Gene3D G3DSA:1.20.120.530 96 234 6.6E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS05050 c16151b6c48becc8a75f160f21c1f6f8 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 7.1E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 Gene3D G3DSA:1.10.10.10 12 86 1.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 Gene3D G3DSA:3.40.640.10 157 404 3.4E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 Pfam PF00155 Aminotransferase class I and II 170 496 2.1E-24 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 Gene3D G3DSA:3.90.1150.10 405 503 6.1E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 3.8E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 SMART SM00345 25 84 2.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 SUPERFAMILY SSF53383 136 499 8.16E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS10745 827a076ba7f6ded6341f0537e629640d 506 SUPERFAMILY SSF46785 20 87 5.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10865 f2ba12a2f044b5d7b6d7b9481c356897 417 SUPERFAMILY SSF103473 20 407 1.11E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10865 f2ba12a2f044b5d7b6d7b9481c356897 417 Gene3D G3DSA:1.20.1250.20 17 209 1.9E-16 T 28-03-2018 hmeg3_RS10865 f2ba12a2f044b5d7b6d7b9481c356897 417 Pfam PF07690 Major Facilitator Superfamily 32 253 1.6E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS10865 f2ba12a2f044b5d7b6d7b9481c356897 417 Pfam PF07690 Major Facilitator Superfamily 279 407 1.9E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS10865 f2ba12a2f044b5d7b6d7b9481c356897 417 Gene3D G3DSA:1.20.1250.20 219 415 9.9E-24 T 28-03-2018 hmeg3_RS20045 e02a6d87d61498a00485c3399c6320b7 248 Gene3D G3DSA:2.40.160.20 28 248 8.9E-29 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS20045 e02a6d87d61498a00485c3399c6320b7 248 Pfam PF03922 OmpW family 30 248 3.8E-28 T 28-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 hmeg3_RS20045 e02a6d87d61498a00485c3399c6320b7 248 SUPERFAMILY SSF56925 57 248 3.4E-18 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 SUPERFAMILY SSF46785 5 85 8.18E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 Pfam PF03466 LysR substrate binding domain 91 291 2.9E-34 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 Gene3D G3DSA:3.40.190.10 85 178 5.7E-20 T 28-03-2018 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 Gene3D G3DSA:1.10.10.10 3 84 1.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 SUPERFAMILY SSF53850 93 292 7.78E-34 T 28-03-2018 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 6.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04975 6502c19ac37e6eb6d2e85b5f93c524ec 304 Gene3D G3DSA:3.40.190.10 179 259 3.0E-17 T 28-03-2018 hmeg3_RS21980 c0b414f261373bdc20832b25a08c3569 168 Gene3D G3DSA:3.40.30.10 1 167 3.3E-26 T 28-03-2018 hmeg3_RS21980 c0b414f261373bdc20832b25a08c3569 168 SUPERFAMILY SSF52833 1 166 1.44E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS21980 c0b414f261373bdc20832b25a08c3569 168 Pfam PF08534 Redoxin 4 164 1.1E-36 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 hmeg3_RS08350 95fd51aaff1e5637849e86438ef4636a 139 SUPERFAMILY SSF101116 10 129 1.1E-35 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 hmeg3_RS08350 95fd51aaff1e5637849e86438ef4636a 139 Pfam PF02561 Flagellar protein FliS 10 127 6.5E-36 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 hmeg3_RS08350 95fd51aaff1e5637849e86438ef4636a 139 PIRSF PIRSF039090 3 138 3.9E-40 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 hmeg3_RS08350 95fd51aaff1e5637849e86438ef4636a 139 Gene3D G3DSA:1.20.120.340 4 131 1.6E-38 T 28-03-2018 hmeg3_RS08350 95fd51aaff1e5637849e86438ef4636a 139 TIGRFAM TIGR00208 fliS: flagellar protein FliS 5 126 3.8E-32 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 hmeg3_RS00215 fba979a54d82ada54143649e3cd8d065 415 SMART SM00471 165 301 3.6E-10 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS00215 fba979a54d82ada54143649e3cd8d065 415 TIGRFAM TIGR00277 HDIG: HDIG domain 169 245 3.8E-8 T 28-03-2018 IPR006675 HDIG domain hmeg3_RS00215 fba979a54d82ada54143649e3cd8d065 415 SUPERFAMILY SSF109604 164 318 9.84E-31 T 28-03-2018 hmeg3_RS00215 fba979a54d82ada54143649e3cd8d065 415 Pfam PF01966 HD domain 170 291 1.3E-13 T 28-03-2018 IPR006674 HD domain hmeg3_RS00215 fba979a54d82ada54143649e3cd8d065 415 Pfam PF11871 Domain of unknown function (DUF3391) 2 138 4.8E-32 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 hmeg3_RS00215 fba979a54d82ada54143649e3cd8d065 415 Gene3D G3DSA:1.10.3210.10 95 335 1.4E-42 T 28-03-2018 hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 Gene3D G3DSA:3.20.20.140 349 382 0.0011 T 28-03-2018 hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 Pfam PF01979 Amidohydrolase family 54 402 3.2E-42 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 SUPERFAMILY SSF51556 58 365 9.9E-87 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 SUPERFAMILY SSF51338 365 402 1.65E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 SUPERFAMILY SSF51338 3 58 1.65E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 Gene3D G3DSA:3.20.20.140 96 348 1.7E-39 T 28-03-2018 hmeg3_RS22400 b33eb48b97f28599417adfe1c1bf2359 410 Gene3D G3DSA:2.30.40.10 1 95 7.5E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS18295 5d10e69975a85b1ff563e7267cd45445 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 7.6E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS18295 5d10e69975a85b1ff563e7267cd45445 309 Gene3D G3DSA:1.10.3470.10 1 298 1.1E-55 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS22515 5d10e69975a85b1ff563e7267cd45445 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 7.6E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22515 5d10e69975a85b1ff563e7267cd45445 309 Gene3D G3DSA:1.10.3470.10 1 298 1.1E-55 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 Gene3D G3DSA:3.30.360.10 127 235 2.9E-36 T 28-03-2018 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 Gene3D G3DSA:3.40.50.720 1 123 2.4E-29 T 28-03-2018 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 266 34.607 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 PIRSF PIRSF000161 2 268 8.9E-86 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 2.5E-94 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 SUPERFAMILY SSF51735 237 267 3.55E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 SUPERFAMILY SSF51735 4 127 3.55E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 SUPERFAMILY SSF55347 128 237 2.4E-38 T 28-03-2018 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 126 5.0E-36 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS20430 578d13e61e194e1444d68255a82053ec 268 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 129 265 1.6E-42 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 PIRSF PIRSF000197 14 1221 0.0 T 28-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 SUPERFAMILY SSF53720 565 1031 7.59E-120 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Pfam PF01619 Proline dehydrogenase 208 502 2.8E-99 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Gene3D G3DSA:3.40.309.10 824 1013 3.8E-46 T 28-03-2018 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Gene3D G3DSA:1.20.5.550 29 77 5.3E-15 T 28-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 SUPERFAMILY SSF81935 28 198 5.75E-64 T 28-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 85 196 3.2E-46 T 28-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 SUPERFAMILY SSF51730 199 545 1.88E-119 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 835 846 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Gene3D G3DSA:3.40.605.10 1037 1170 0.22 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Pfam PF00171 Aldehyde dehydrogenase family 589 1027 1.2E-108 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Gene3D G3DSA:3.40.605.10 563 823 2.7E-65 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 Gene3D G3DSA:3.20.20.220 123 536 1.9E-104 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like hmeg3_RS22490 d8e20ff9f5ffd48adeaa91859fd83a96 1222 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 537 1030 3.8E-231 T 28-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 Gene3D G3DSA:3.40.50.2300 1 141 7.1E-22 T 28-03-2018 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 SUPERFAMILY SSF52172 2 102 3.56E-21 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 SUPERFAMILY SSF52738 166 347 8.76E-59 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 349 31.199 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 PIRSF PIRSF000876 1 349 5.0E-99 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 SMART SM00448 1 125 7.7E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 Gene3D G3DSA:3.40.50.180 158 349 9.8E-70 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 Pfam PF01339 CheB methylesterase 168 344 8.0E-57 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS14880 2ba024d8528f936bfcc31cf0e8acfb44 349 Pfam PF00072 Response regulator receiver domain 3 102 6.3E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS00685 919fb0e5ae3b57510f2e4f7ca6b63fdc 499 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 478 1.3E-126 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS00685 919fb0e5ae3b57510f2e4f7ca6b63fdc 499 Gene3D G3DSA:1.20.1600.10 29 484 2.5E-105 T 28-03-2018 hmeg3_RS00685 919fb0e5ae3b57510f2e4f7ca6b63fdc 499 Pfam PF02321 Outer membrane efflux protein 296 470 3.4E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00685 919fb0e5ae3b57510f2e4f7ca6b63fdc 499 Pfam PF02321 Outer membrane efflux protein 73 263 5.5E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00685 919fb0e5ae3b57510f2e4f7ca6b63fdc 499 SUPERFAMILY SSF56954 15 481 4.45E-116 T 28-03-2018 hmeg3_RS22720 0d5a4bcc6f8842fd6bb85d88c966fe24 313 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS22720 0d5a4bcc6f8842fd6bb85d88c966fe24 313 SUPERFAMILY SSF52540 9 234 7.52E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS22720 0d5a4bcc6f8842fd6bb85d88c966fe24 313 Pfam PF00005 ABC transporter 30 172 3.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS22720 0d5a4bcc6f8842fd6bb85d88c966fe24 313 Gene3D G3DSA:3.40.50.300 6 267 2.7E-70 T 28-03-2018 hmeg3_RS22720 0d5a4bcc6f8842fd6bb85d88c966fe24 313 SMART SM00382 38 220 1.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22015 aad1877dada1e6c4bedf8715e76efd22 421 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 50 411 3.8E-119 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 hmeg3_RS22015 aad1877dada1e6c4bedf8715e76efd22 421 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 47 420 38.948 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 hmeg3_RS22015 aad1877dada1e6c4bedf8715e76efd22 421 Pfam PF01098 Cell cycle protein 53 413 2.3E-101 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 28 578 8.9E-126 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 SMART SM01016 7 95 4.2E-34 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Pfam PF00750 tRNA synthetases class I (R) 104 406 1.5E-24 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 SUPERFAMILY SSF52374 118 470 5.91E-81 T 28-03-2018 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Gene3D G3DSA:1.10.730.10 426 578 4.4E-46 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 578 25.347 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 SMART SM00836 460 578 1.6E-52 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Gene3D G3DSA:3.40.50.620 110 376 8.7E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Pfam PF05746 DALR anticodon binding domain 460 578 6.5E-35 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 1.6E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 312 333 1.6E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 1.6E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 1.6E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 SUPERFAMILY SSF47323 455 578 3.27E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 94 5.0E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 SUPERFAMILY SSF55190 5 115 5.89E-21 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS02495 7ace5ce17ac2d0e7951ed10a6ab106e7 578 Gene3D G3DSA:3.30.1360.70 1 109 5.7E-32 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 7 410 2.8E-199 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 SUPERFAMILY SSF53901 217 412 4.61E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 SMART SM00825 Beta-ketoacyl synthase 9 410 6.0E-16 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 Gene3D G3DSA:3.40.47.10 9 263 9.4E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 Gene3D G3DSA:3.40.47.10 264 413 2.7E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 250 5.2E-61 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 158 174 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 PIRSF PIRSF000447 4 413 3.4E-187 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 SUPERFAMILY SSF53901 7 255 7.13E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16725 88949cc221e1649d4868dd5fb52f23ce 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 258 370 2.9E-35 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal hmeg3_RS18215 0bae6f16b3704fabed96f1004162e973 57 Pfam PF05532 CsbD-like 4 56 3.3E-15 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS18215 0bae6f16b3704fabed96f1004162e973 57 Gene3D G3DSA:1.10.1470.10 1 57 3.9E-15 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS18215 0bae6f16b3704fabed96f1004162e973 57 SUPERFAMILY SSF69047 1 56 6.15E-15 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 SUPERFAMILY SSF51735 9 255 1.79E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 212 0.0093 T 28-03-2018 hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 Gene3D G3DSA:3.40.50.720 1 42 2.5E-6 T 28-03-2018 hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 Gene3D G3DSA:3.40.50.720 43 255 2.0E-53 T 28-03-2018 hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 254 1.4E-53 T 28-03-2018 hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00065 4e1fbe07e872f8275e10ce5800b78a0d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14330 10cefbf870ed49ce3f3d853f7d51b002 240 PIRSF PIRSF039085 1 240 1.2E-118 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS14330 10cefbf870ed49ce3f3d853f7d51b002 240 SUPERFAMILY SSF52540 1 235 1.9E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14330 10cefbf870ed49ce3f3d853f7d51b002 240 SMART SM00382 26 213 1.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14330 10cefbf870ed49ce3f3d853f7d51b002 240 Pfam PF00005 ABC transporter 17 165 7.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14330 10cefbf870ed49ce3f3d853f7d51b002 240 Gene3D G3DSA:3.40.50.300 1 239 1.1E-75 T 28-03-2018 hmeg3_RS14330 10cefbf870ed49ce3f3d853f7d51b002 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS05800 7e0a8a5731f0bef1ac084bf523922dd1 406 Gene3D G3DSA:3.40.50.2300 29 207 8.8E-26 T 28-03-2018 hmeg3_RS05800 7e0a8a5731f0bef1ac084bf523922dd1 406 Pfam PF13458 Periplasmic binding protein 42 374 9.8E-43 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS05800 7e0a8a5731f0bef1ac084bf523922dd1 406 SUPERFAMILY SSF53822 40 383 1.15E-64 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS05800 7e0a8a5731f0bef1ac084bf523922dd1 406 Gene3D G3DSA:3.40.50.2300 208 366 3.0E-17 T 28-03-2018 hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 SUPERFAMILY SSF54631 214 358 1.95E-19 T 28-03-2018 hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 Pfam PF03471 Transporter associated domain 355 429 8.4E-17 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 Gene3D G3DSA:3.30.465.10 352 432 8.4E-19 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 Pfam PF01595 Domain of unknown function DUF21 9 195 6.9E-48 T 28-03-2018 IPR002550 Domain of unknown function DUF21 hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 Gene3D G3DSA:3.10.580.10 200 351 2.6E-23 T 28-03-2018 hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 SMART SM01091 354 432 1.4E-20 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 SUPERFAMILY SSF56176 352 431 5.18E-16 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS06120 fbb07145d22eb23c1c355555a5df9126 444 Pfam PF00571 CBS domain 288 339 0.0023 T 28-03-2018 IPR000644 CBS domain hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 Pfam PF06463 Molybdenum Cofactor Synthesis C 221 348 6.9E-37 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 Pfam PF13394 4Fe-4S single cluster domain 47 138 3.7E-9 T 28-03-2018 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 SUPERFAMILY SSF102114 32 325 1.24E-75 T 28-03-2018 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 31 369 1.7E-114 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 Pfam PF04055 Radical SAM superfamily 44 213 1.2E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 46 57 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 Gene3D G3DSA:3.20.20.70 27 369 5.3E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 SMART SM00729 40 254 4.2E-9 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS02285 05e92436a8a74567f6dafd51fa75c4eb 369 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 31 369 40.584 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 Gene3D G3DSA:3.40.605.10 294 423 5.7E-26 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 8 422 42.098 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 Pfam PF00171 Aldehyde dehydrogenase family 14 289 6.2E-19 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 Pfam PF00171 Aldehyde dehydrogenase family 315 379 2.1E-8 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 350 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 16 412 2.3E-153 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 PIRSF PIRSF000151 1 423 2.9E-178 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 Gene3D G3DSA:3.40.309.10 242 293 1.6E-7 T 28-03-2018 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 Gene3D G3DSA:3.40.605.10 6 241 3.8E-44 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20495 e52ec9a2fee87d8e43ccfa4a614a9458 423 SUPERFAMILY SSF53720 8 422 1.09E-122 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS07335 97aba77977a8ce2ddd11c425ffb7abe0 492 SUPERFAMILY SSF103473 26 217 1.29E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07335 97aba77977a8ce2ddd11c425ffb7abe0 492 SUPERFAMILY SSF103473 270 488 1.29E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07335 97aba77977a8ce2ddd11c425ffb7abe0 492 Pfam PF07690 Major Facilitator Superfamily 47 443 6.1E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS07335 97aba77977a8ce2ddd11c425ffb7abe0 492 Gene3D G3DSA:1.20.1250.20 38 222 7.0E-23 T 28-03-2018 hmeg3_RS07335 97aba77977a8ce2ddd11c425ffb7abe0 492 Gene3D G3DSA:1.20.1250.20 283 491 7.8E-9 T 28-03-2018 hmeg3_RS23080 db7eeeee380b72c587423114716c2a3a 85 Pfam PF12091 Protein of unknown function (DUF3567) 1 85 1.0E-32 T 28-03-2018 IPR021951 Protein of unknown function DUF3567 hmeg3_RS05935 9c1a10095dccb44bbd70b95d3595fa79 377 Gene3D G3DSA:3.60.21.10 149 363 2.5E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS05935 9c1a10095dccb44bbd70b95d3595fa79 377 SUPERFAMILY SSF56300 152 374 1.18E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS05935 9c1a10095dccb44bbd70b95d3595fa79 377 Pfam PF00149 Calcineurin-like phosphoesterase 152 319 9.3E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 Gene3D G3DSA:3.40.50.300 499 645 2.5E-8 T 28-03-2018 hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 Gene3D G3DSA:1.10.486.10 646 803 3.2E-24 T 28-03-2018 hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 Gene3D G3DSA:3.40.50.300 22 494 4.7E-50 T 28-03-2018 hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 SUPERFAMILY SSF52540 371 525 4.16E-101 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 SUPERFAMILY SSF52540 31 92 4.16E-101 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 SUPERFAMILY SSF52540 132 205 4.16E-101 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 SUPERFAMILY SSF52540 888 914 4.16E-101 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 SUPERFAMILY SSF52540 553 843 4.16E-101 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 Gene3D G3DSA:3.90.320.10 804 1122 1.7E-4 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 Pfam PF13361 UvrD-like helicase C-terminal domain 581 910 2.2E-22 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS19520 a0d81493b418cb998d672e918de0229b 1131 Pfam PF00580 UvrD/REP helicase N-terminal domain 32 486 2.6E-50 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 hmeg3_RS05290 dbd05fde0a46f832a6549707399c36ed 145 SUPERFAMILY SSF55729 8 128 3.31E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS05290 dbd05fde0a46f832a6549707399c36ed 145 Pfam PF00583 Acetyltransferase (GNAT) family 25 126 1.8E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS05290 dbd05fde0a46f832a6549707399c36ed 145 Gene3D G3DSA:3.40.630.30 1 130 2.0E-16 T 28-03-2018 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Pfam PF02785 Biotin carboxylase C-terminal domain 336 455 1.6E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 8.5E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Gene3D G3DSA:3.30.470.20 210 457 1.2E-107 T 28-03-2018 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 SUPERFAMILY SSF56059 83 348 2.12E-68 T 28-03-2018 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 SMART SM00878 336 454 2.6E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Gene3D G3DSA:2.40.50.100 598 668 3.9E-18 T 28-03-2018 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 SUPERFAMILY SSF52440 1 113 1.15E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Gene3D G3DSA:3.30.1490.20 124 209 1.9E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Gene3D G3DSA:3.40.50.20 1 123 3.2E-53 T 28-03-2018 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Pfam PF00364 Biotin-requiring enzyme 602 665 1.3E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 SUPERFAMILY SSF51246 331 460 4.03E-39 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 3.7E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 SUPERFAMILY SSF51230 587 666 2.36E-20 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS00580 d5f02775d3e26e81c578040c8497ca18 670 SMART SM01209 114 293 0.0023 T 28-03-2018 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 Pfam PF03466 LysR substrate binding domain 86 295 2.3E-16 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 Gene3D G3DSA:3.40.190.10 84 178 5.9E-4 T 28-03-2018 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 SUPERFAMILY SSF53850 86 297 3.98E-15 T 28-03-2018 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 Gene3D G3DSA:3.40.190.10 179 257 6.2E-7 T 28-03-2018 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 Gene3D G3DSA:1.10.10.10 1 83 3.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.2E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01800 5fa92ff17c580f1d85580a6b07a8a63b 301 SUPERFAMILY SSF46785 1 84 6.43E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 Gene3D G3DSA:1.10.10.10 119 223 4.9E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 1.5E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 Pfam PF00072 Response regulator receiver domain 3 112 2.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 SMART SM00862 144 219 4.4E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 1.1E-104 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 SUPERFAMILY SSF52172 1 175 9.16E-40 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 SMART SM00448 1 111 1.4E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02200 da278057fc368a0490637f6c1db065b7 223 Gene3D G3DSA:3.40.50.2300 1 118 2.6E-33 T 28-03-2018 hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 Pfam PF00561 alpha/beta hydrolase fold 35 258 4.0E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 1.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 SUPERFAMILY SSF53474 11 271 1.59E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS19260 1dc944a293c7d916c66e9032ce77dce9 274 Gene3D G3DSA:3.40.50.1820 9 268 3.0E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS22530 d8ee3321fe96bbdc7ab7a64c961a0676 375 Pfam PF13458 Periplasmic binding protein 26 367 3.8E-58 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS22530 d8ee3321fe96bbdc7ab7a64c961a0676 375 Gene3D G3DSA:3.40.50.2300 288 368 1.6E-9 T 28-03-2018 hmeg3_RS22530 d8ee3321fe96bbdc7ab7a64c961a0676 375 Gene3D G3DSA:3.40.50.2300 154 287 6.4E-35 T 28-03-2018 hmeg3_RS22530 d8ee3321fe96bbdc7ab7a64c961a0676 375 Gene3D G3DSA:3.40.50.2300 25 153 9.6E-16 T 28-03-2018 hmeg3_RS22530 d8ee3321fe96bbdc7ab7a64c961a0676 375 SUPERFAMILY SSF53822 26 368 7.57E-87 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 3.0E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 Pfam PF00672 HAMP domain 213 261 3.6E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 Gene3D G3DSA:1.10.287.950 324 517 4.3E-50 T 28-03-2018 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 SUPERFAMILY SSF58104 233 514 8.63E-77 T 28-03-2018 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 Gene3D G3DSA:1.10.287.1060 220 323 0.16 T 28-03-2018 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 Gene3D G3DSA:1.20.120.30 26 187 8.9E-23 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 185 1.3E-36 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 SMART SM00304 213 265 9.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 SMART SM00283 266 513 1.9E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 2.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 2.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 2.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 190 210 2.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 42 2.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00975 6f97f898d8d93379be56c3b2e71eff0b 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 2.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09200 d3452f4f4991ee537fe3a12a1223762d 268 SUPERFAMILY SSF53850 30 260 2.09E-48 T 28-03-2018 hmeg3_RS09200 d3452f4f4991ee537fe3a12a1223762d 268 Gene3D G3DSA:3.40.190.10 150 256 1.2E-7 T 28-03-2018 hmeg3_RS09200 d3452f4f4991ee537fe3a12a1223762d 268 SMART SM00062 38 258 7.5E-30 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09200 d3452f4f4991ee537fe3a12a1223762d 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 256 3.2E-43 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09200 d3452f4f4991ee537fe3a12a1223762d 268 Gene3D G3DSA:3.40.190.10 33 149 1.3E-28 T 28-03-2018 hmeg3_RS14500 279387a8dcbbfc345f78de97348d202c 372 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 108 335 5.3E-59 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 hmeg3_RS14500 279387a8dcbbfc345f78de97348d202c 372 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 192 209 1.3E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 hmeg3_RS14500 279387a8dcbbfc345f78de97348d202c 372 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 219 232 1.3E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 hmeg3_RS14500 279387a8dcbbfc345f78de97348d202c 372 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 153 1.3E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 hmeg3_RS14500 279387a8dcbbfc345f78de97348d202c 372 SUPERFAMILY SSF56601 114 351 1.79E-56 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS14500 279387a8dcbbfc345f78de97348d202c 372 Gene3D G3DSA:3.40.710.10 17 361 4.8E-43 T 28-03-2018 hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 Pfam PF09339 IclR helix-turn-helix domain 20 70 5.1E-17 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 Gene3D G3DSA:1.10.10.10 14 86 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 SUPERFAMILY SSF46785 19 90 1.47E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 SMART SM00346 18 108 1.5E-28 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 Pfam PF01614 Bacterial transcriptional regulator 138 261 1.2E-30 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 Gene3D G3DSA:3.30.450.40 87 266 2.4E-44 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS15635 4fed1d2a2cb8b412caca5da7410b77a7 267 SUPERFAMILY SSF55781 85 262 9.16E-46 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 Pfam PF00672 HAMP domain 211 259 2.5E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 SMART SM00304 211 263 2.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 20 3.0E-16 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 376 403 3.0E-16 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 3.0E-16 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 504 6.0E-34 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 Gene3D G3DSA:1.10.287.950 319 542 8.8E-47 T 28-03-2018 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 Gene3D G3DSA:1.10.287.950 87 318 1.3E-8 T 28-03-2018 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 179 5.0E-21 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 SUPERFAMILY SSF58104 231 540 7.98E-61 T 28-03-2018 hmeg3_RS14905 75462b807c71edd6aa59d1867911c5cf 542 SMART SM00283 271 539 1.8E-48 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 2.1E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 SMART SM00448 1 112 5.2E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 Gene3D G3DSA:1.10.10.10 120 225 6.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 Pfam PF00072 Response regulator receiver domain 3 112 2.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 SMART SM00862 145 221 5.8E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 Gene3D G3DSA:3.40.50.2300 1 119 4.9E-36 T 28-03-2018 hmeg3_RS02700 b7229ec94278f126ef1a4e902a5a45bb 225 SUPERFAMILY SSF52172 1 177 8.25E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 Pfam PF01479 S4 domain 6 44 1.0E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 SUPERFAMILY SSF55174 4 50 1.02E-7 T 28-03-2018 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 Gene3D G3DSA:3.10.290.10 3 58 2.4E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 103 117 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 Gene3D G3DSA:3.30.70.1560 148 208 2.2E-15 T 28-03-2018 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 Gene3D G3DSA:3.30.70.580 59 147 2.5E-17 T 28-03-2018 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 69 228 1.0E-36 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 SUPERFAMILY SSF55120 49 231 1.01E-38 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS14010 1ac5c6a4cff8e032dd77a6377d8e5a52 240 Pfam PF00849 RNA pseudouridylate synthase 65 196 2.1E-15 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 Gene3D G3DSA:2.40.30.20 1 91 5.6E-19 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 PIRSF PIRSF000498 1 204 2.0E-67 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 SUPERFAMILY SSF63380 1 90 6.55E-18 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 203 1.6E-54 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 Gene3D G3DSA:2.40.30.20 96 197 6.9E-33 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 SUPERFAMILY SSF63380 95 201 1.45E-31 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 Pfam PF00677 Lumazine binding domain 3 88 2.2E-14 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05145 cee264bdd931be14b5a1a2215c006a82 204 Pfam PF00677 Lumazine binding domain 102 190 6.4E-23 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS13360 16d6137ecf090fc77acb878b02e7afb3 742 Pfam PF12805 FUSC-like inner membrane protein yccS 68 336 4.4E-57 T 28-03-2018 IPR032692 Integral membrane protein YccS, N-terminal hmeg3_RS13360 16d6137ecf090fc77acb878b02e7afb3 742 Pfam PF13515 Fusaric acid resistance protein-like 406 528 6.9E-18 T 28-03-2018 hmeg3_RS21840 b23934fc3ab2fd3725178ff5a579f8bf 153 Pfam PF02201 SWIB/MDM2 domain 79 152 5.9E-29 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 hmeg3_RS21840 b23934fc3ab2fd3725178ff5a579f8bf 153 Gene3D G3DSA:1.10.245.10 60 153 2.2E-28 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 hmeg3_RS21840 b23934fc3ab2fd3725178ff5a579f8bf 153 SUPERFAMILY SSF47592 72 152 2.03E-26 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 hmeg3_RS21840 b23934fc3ab2fd3725178ff5a579f8bf 153 SMART SM00151 77 153 3.5E-33 T 28-03-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858 hmeg3_RS22240 fe98d73e83c28b5699994cbce155f63c 534 Gene3D G3DSA:3.10.20.310 20 90 2.3E-15 T 28-03-2018 hmeg3_RS22240 fe98d73e83c28b5699994cbce155f63c 534 Pfam PF08479 POTRA domain, ShlB-type 16 90 1.8E-16 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type hmeg3_RS22240 fe98d73e83c28b5699994cbce155f63c 534 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 155 486 1.3E-30 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal hmeg3_RS22240 fe98d73e83c28b5699994cbce155f63c 534 Gene3D G3DSA:2.40.160.50 123 531 1.3E-37 T 28-03-2018 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 Pfam PF01479 S4 domain 357 396 1.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 Gene3D G3DSA:3.10.290.10 337 411 1.5E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 64 86 9.4E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 196 218 9.4E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 229 241 9.4E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 179 194 9.4E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 70 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 Gene3D G3DSA:3.40.50.620 13 236 2.4E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 SUPERFAMILY SSF52374 22 331 3.15E-90 T 28-03-2018 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 SUPERFAMILY SSF55174 315 411 1.57E-18 T 28-03-2018 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 16 412 46.972 T 28-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 Pfam PF00579 tRNA synthetases class I (W and Y) 49 327 1.2E-73 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 SMART SM00363 352 413 8.8E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 Gene3D G3DSA:1.10.240.10 237 336 1.1E-22 T 28-03-2018 hmeg3_RS21675 760272efc332ab7326227967a377f3af 413 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 21 411 2.1E-113 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 hmeg3_RS11920 c07aa4c994c2759898ace3b64de69b11 189 SUPERFAMILY SSF81342 17 188 3.06E-31 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 hmeg3_RS11920 c07aa4c994c2759898ace3b64de69b11 189 Gene3D G3DSA:1.20.950.20 11 189 4.2E-31 T 28-03-2018 hmeg3_RS11920 c07aa4c994c2759898ace3b64de69b11 189 Pfam PF01292 Prokaryotic cytochrome b561 17 188 5.4E-27 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.25.40.10 9 63 8.5E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.25.40.10 213 266 6.2E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.25.40.10 145 198 5.5E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.25.40.10 77 130 2.1E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Pfam PF13414 TPR repeat 153 190 1.2E-9 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Pfam PF00515 Tetratricopeptide repeat 113 145 6.8E-8 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.10.287.1110 199 212 4.6E-6 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.10.287.1110 64 76 0.002 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.10.287.1110 131 144 5.2E-4 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Pfam PF14559 Tetratricopeptide repeat 229 285 7.8E-6 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 44 77 1.8E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 112 145 2.2E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 78 111 0.95 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 180 213 7.3E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 10 43 0.0036 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 146 179 1.6E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 248 281 61.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SMART SM00028 214 247 0.22 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Pfam PF13432 Tetratricopeptide repeat 16 76 1.4E-10 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SUPERFAMILY SSF53756 335 462 3.98E-5 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 536 570 2.3E-5 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:3.40.50.2000 334 618 4.4E-33 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SUPERFAMILY SSF53756 532 600 5.02E-13 T 28-03-2018 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SUPERFAMILY SSF48452 224 309 1.14E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 Gene3D G3DSA:1.25.40.10 267 322 3.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18960 2665b07db2bee096b0baed32d0ef301e 620 SUPERFAMILY SSF48452 12 249 2.02E-48 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23260 318faf4cb0601c69838205168066b064 398 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 19 376 7.7E-105 T 28-03-2018 IPR010640 Low temperature requirement A hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 Pfam PF13609 Gram-negative porin 7 325 4.1E-50 T 28-03-2018 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 Gene3D G3DSA:2.40.160.10 8 361 8.6E-66 T 28-03-2018 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 182 194 2.6E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 94 104 2.6E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 50 61 2.6E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 154 165 2.6E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 301 318 2.6E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00184 Neisseria sp. porin signature 310 336 3.0E-9 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00184 Neisseria sp. porin signature 153 170 3.0E-9 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 PRINTS PR00184 Neisseria sp. porin signature 52 77 3.0E-9 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS00180 adf456b120f58006977abe3e4288edb0 361 SUPERFAMILY SSF56935 20 361 2.53E-75 T 28-03-2018 hmeg3_RS02475 d30fc5668f10d83a1ed03845feb55b11 257 SUPERFAMILY SSF53850 1 256 2.77E-49 T 28-03-2018 hmeg3_RS02475 d30fc5668f10d83a1ed03845feb55b11 257 Gene3D G3DSA:3.40.190.10 26 148 2.0E-23 T 28-03-2018 hmeg3_RS02475 d30fc5668f10d83a1ed03845feb55b11 257 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 256 7.5E-38 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS02475 d30fc5668f10d83a1ed03845feb55b11 257 Gene3D G3DSA:3.40.190.10 154 257 2.4E-8 T 28-03-2018 hmeg3_RS02475 d30fc5668f10d83a1ed03845feb55b11 257 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS02475 d30fc5668f10d83a1ed03845feb55b11 257 SMART SM00062 36 257 1.6E-37 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04675 d4a05aefd75f805003736f2e197a12e3 315 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 267 3.4E-45 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04675 d4a05aefd75f805003736f2e197a12e3 315 Gene3D G3DSA:3.40.190.10 143 231 1.5E-16 T 28-03-2018 hmeg3_RS04675 d4a05aefd75f805003736f2e197a12e3 315 Gene3D G3DSA:3.40.190.10 27 142 4.1E-23 T 28-03-2018 hmeg3_RS04675 d4a05aefd75f805003736f2e197a12e3 315 SMART SM00062 37 269 1.1E-51 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04675 d4a05aefd75f805003736f2e197a12e3 315 SUPERFAMILY SSF53850 1 270 2.75E-54 T 28-03-2018 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:2.30.30.40 1366 1430 4.7E-15 T 28-03-2018 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM01231 977 1113 3.9E-6 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1162 1298 6.3E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM00073 657 754 0.058 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM00073 500 604 0.018 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM00073 825 925 2.0E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM00260 1291 1430 2.4E-16 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM00387 1158 1299 2.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SUPERFAMILY SSF47226 659 778 4.45E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF00072 Response regulator receiver domain 1456 1567 5.5E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:3.30.565.10 1110 1300 5.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF01627 Hpt domain 502 581 1.2E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF01627 Hpt domain 661 750 1.2E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF01627 Hpt domain 827 898 1.8E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF01584 CheW-like domain 1303 1431 5.9E-19 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:3.40.50.2300 1445 1589 2.6E-37 T 28-03-2018 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SUPERFAMILY SSF52172 1453 1572 1.85E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 980 1112 2.7E-5 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SMART SM00448 1454 1567 2.5E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SUPERFAMILY SSF47226 500 622 7.85E-19 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:1.10.287.560 978 1109 7.8E-7 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SUPERFAMILY SSF55874 1115 1297 2.88E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SUPERFAMILY SSF47226 824 934 8.24E-22 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:1.20.120.160 657 797 5.4E-13 T 28-03-2018 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1203 1217 4.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1259 1277 4.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1283 1296 4.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1243 1253 4.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 SUPERFAMILY SSF50341 1298 1429 4.32E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:1.20.120.160 496 640 9.3E-23 T 28-03-2018 hmeg3_RS04775 988f74b95de6a9e2115021807fae8501 1619 Gene3D G3DSA:1.20.120.160 823 952 1.6E-22 T 28-03-2018 hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 SUPERFAMILY SSF47384 216 299 2.16E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 441 6.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 Gene3D G3DSA:1.10.287.130 217 313 1.2E-4 T 28-03-2018 hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 Gene3D G3DSA:3.30.565.10 314 454 9.0E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 SUPERFAMILY SSF55874 288 449 2.88E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 2.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 2.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 SMART SM00387 344 454 7.1E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 SMART SM00304 179 232 5.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02220 eef55709fc484069ee8a4700aeb4d80e 454 SUPERFAMILY SSF158472 180 231 3.27E-7 T 28-03-2018 hmeg3_RS06935 d65ead5d81d4cdc794c6c400e6f9c93a 371 Gene3D G3DSA:3.20.20.70 1 370 4.3E-122 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS06935 d65ead5d81d4cdc794c6c400e6f9c93a 371 SUPERFAMILY SSF51395 3 353 6.11E-118 T 28-03-2018 hmeg3_RS06935 d65ead5d81d4cdc794c6c400e6f9c93a 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 342 2.9E-77 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 487 7.5E-116 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 SUPERFAMILY SSF51735 9 192 1.44E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 14 189 7.5E-56 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 SUPERFAMILY SSF55347 179 488 3.2E-113 T 28-03-2018 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 Gene3D G3DSA:3.40.50.720 8 190 3.9E-59 T 28-03-2018 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 4.3E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 4.3E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 4.3E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 4.3E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 4.3E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 10 489 79.453 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 13 489 1.6E-174 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 Gene3D G3DSA:3.30.360.10 191 490 4.7E-128 T 28-03-2018 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 PIRSF PIRSF000110 1 491 2.3E-170 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS19110 311217adbbdbdf3b68baeb2fd01388c8 491 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 179 185 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS24070 789e156fa5ea21498991f3c6fcbe8365 299 Pfam PF01522 Polysaccharide deacetylase 43 173 1.3E-12 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 hmeg3_RS24070 789e156fa5ea21498991f3c6fcbe8365 299 Gene3D G3DSA:3.20.20.370 33 258 2.6E-29 T 28-03-2018 hmeg3_RS24070 789e156fa5ea21498991f3c6fcbe8365 299 SUPERFAMILY SSF88713 43 257 2.64E-28 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 Gene3D G3DSA:1.20.1560.10 18 338 5.8E-29 T 28-03-2018 hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 Pfam PF00005 ABC transporter 381 534 1.8E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 SUPERFAMILY SSF90123 19 338 1.7E-47 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 Pfam PF00664 ABC transporter transmembrane region 42 306 2.7E-11 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 Gene3D G3DSA:3.40.50.300 344 607 2.9E-75 T 28-03-2018 hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 SMART SM00382 389 580 1.2E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 SUPERFAMILY SSF52540 351 604 7.01E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24115 55a580ad8f9fe7b2bd745115725bae69 613 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06995 0441b89d0374015fbc2f2f675aab21fc 348 Gene3D G3DSA:1.10.3720.10 2 331 3.0E-38 T 28-03-2018 hmeg3_RS06995 0441b89d0374015fbc2f2f675aab21fc 348 SUPERFAMILY SSF161098 114 325 1.27E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS06995 0441b89d0374015fbc2f2f675aab21fc 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 341 7.8E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23125 db891663fc304a2b6db07d0a9cd6375b 273 PIRSF PIRSF002854 1 273 1.4E-96 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS23125 db891663fc304a2b6db07d0a9cd6375b 273 Gene3D G3DSA:3.40.190.10 126 273 8.1E-48 T 28-03-2018 hmeg3_RS23125 db891663fc304a2b6db07d0a9cd6375b 273 Pfam PF03180 NLPA lipoprotein 32 273 1.0E-83 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS23125 db891663fc304a2b6db07d0a9cd6375b 273 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 273 6.6E-73 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS23125 db891663fc304a2b6db07d0a9cd6375b 273 Gene3D G3DSA:3.40.190.10 31 125 7.7E-20 T 28-03-2018 hmeg3_RS23125 db891663fc304a2b6db07d0a9cd6375b 273 SUPERFAMILY SSF53850 31 273 9.62E-80 T 28-03-2018 hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 SMART SM00052 501 747 2.9E-111 T 28-03-2018 IPR001633 EAL domain hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 SMART SM00267 317 491 1.7E-64 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 SUPERFAMILY SSF55073 334 492 6.59E-50 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 Gene3D G3DSA:3.30.70.270 322 494 2.2E-60 T 28-03-2018 hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 Gene3D G3DSA:3.20.20.450 495 758 4.6E-99 T 28-03-2018 IPR001633 EAL domain hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 SUPERFAMILY SSF141868 508 754 8.24E-88 T 28-03-2018 IPR001633 EAL domain hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 Pfam PF00990 Diguanylate cyclase, GGDEF domain 329 485 3.4E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 Pfam PF00563 EAL domain 508 742 3.3E-72 T 28-03-2018 IPR001633 EAL domain hmeg3_RS04220 8d5a92669271c2637de9230d1164316e 760 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 328 489 2.5E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16985 e5eb7be4ae7fa7845f72f2d1dd53f31d 426 Gene3D G3DSA:1.10.760.10 307 423 2.4E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS16985 e5eb7be4ae7fa7845f72f2d1dd53f31d 426 SUPERFAMILY SSF46626 327 424 3.36E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS16985 e5eb7be4ae7fa7845f72f2d1dd53f31d 426 Pfam PF06181 Urate oxidase N-terminal 8 304 5.2E-140 T 28-03-2018 IPR010389 Urate oxidase N-terminal hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 228 2.6E-85 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 6 110 2.9E-34 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 SUPERFAMILY SSF54292 2 105 6.18E-30 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 Gene3D G3DSA:3.10.20.30 1 105 6.6E-34 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 SUPERFAMILY SSF46548 106 233 3.49E-37 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 Gene3D G3DSA:1.10.1060.10 106 236 1.1E-30 T 28-03-2018 hmeg3_RS08765 4173dc136a708f47ac0b3c754ed1e285 236 Pfam PF13534 4Fe-4S dicluster domain 146 219 3.3E-9 T 28-03-2018 hmeg3_RS11020 7bbcb329fe3f258bdd190df9f801a8cd 303 SUPERFAMILY SSF53067 6 115 1.3E-18 T 28-03-2018 hmeg3_RS11020 7bbcb329fe3f258bdd190df9f801a8cd 303 Gene3D G3DSA:3.30.420.40 1 130 1.7E-16 T 28-03-2018 hmeg3_RS11020 7bbcb329fe3f258bdd190df9f801a8cd 303 Gene3D G3DSA:3.30.420.40 131 283 6.5E-32 T 28-03-2018 hmeg3_RS11020 7bbcb329fe3f258bdd190df9f801a8cd 303 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 9 281 2.0E-25 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 hmeg3_RS11020 7bbcb329fe3f258bdd190df9f801a8cd 303 SUPERFAMILY SSF53067 118 295 1.4E-36 T 28-03-2018 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 Gene3D G3DSA:1.10.287.950 113 320 2.6E-18 T 28-03-2018 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 Gene3D G3DSA:1.10.287.950 321 517 1.0E-48 T 28-03-2018 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 5.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 5.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 191 211 5.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 5.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 5.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 5.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 1.0E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 SMART SM00283 266 513 5.6E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 Pfam PF00672 HAMP domain 213 260 5.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 SUPERFAMILY SSF58104 233 514 2.62E-74 T 28-03-2018 hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 174 3.6E-16 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS00400 56543735fd3ebf49b02e769cfdd18ed9 517 SMART SM00304 213 265 1.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 ProSitePatterns PS00211 ABC transporters family signature. 418 432 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 Gene3D G3DSA:3.40.50.300 265 503 7.3E-38 T 28-03-2018 hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 Gene3D G3DSA:3.40.50.300 11 258 8.3E-46 T 28-03-2018 hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 Pfam PF00005 ABC transporter 295 445 1.4E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 Pfam PF00005 ABC transporter 30 182 3.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 SMART SM00382 39 230 4.9E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 SMART SM00382 300 494 8.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 SUPERFAMILY SSF52540 13 239 5.11E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19020 db48313227c0b609aa286e2012e02382 530 SUPERFAMILY SSF52540 286 494 2.17E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08180 737f68a08fd452eac774f27ccdc99811 104 Gene3D G3DSA:1.10.287.1160 64 92 6.1E-14 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 hmeg3_RS08180 737f68a08fd452eac774f27ccdc99811 104 SUPERFAMILY SSF101498 22 94 4.05E-15 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 hmeg3_RS08180 737f68a08fd452eac774f27ccdc99811 104 Pfam PF04316 Anti-sigma-28 factor, FlgM 41 92 2.1E-14 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal hmeg3_RS08180 737f68a08fd452eac774f27ccdc99811 104 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 18 95 1.2E-20 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 Gene3D G3DSA:3.40.50.80 100 212 2.1E-19 T 28-03-2018 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 SUPERFAMILY SSF52343 94 224 2.62E-26 T 28-03-2018 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 Pfam PF00175 Oxidoreductase NAD-binding domain 110 200 1.3E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 SUPERFAMILY SSF63380 2 96 3.62E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 26 36 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 48 62 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 108 127 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 72 86 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 86 100 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 133 142 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 36 48 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 187 195 3.2E-41 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 Gene3D G3DSA:3.10.20.30 213 314 9.2E-18 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 263 271 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 237 305 8.6E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 Gene3D G3DSA:2.40.30.10 1 99 3.0E-16 T 28-03-2018 hmeg3_RS01185 f69c26e9619a24fbbfc69e44c238d989 314 SUPERFAMILY SSF54292 210 313 5.64E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 SUPERFAMILY SSF53955 60 272 5.91E-77 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 Pfam PF17092 Penicillin-binding protein OB-like domain 334 438 3.9E-22 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 Gene3D G3DSA:3.40.710.10 260 737 6.8E-117 T 28-03-2018 hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 Gene3D G3DSA:1.10.3810.10 66 259 1.2E-78 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 SUPERFAMILY SSF56601 435 744 1.57E-114 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 SUPERFAMILY SSF56601 229 251 1.57E-114 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 SUPERFAMILY SSF56601 280 331 1.57E-114 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 83 723 4.1E-187 T 28-03-2018 hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 Pfam PF00905 Penicillin binding protein transpeptidase domain 442 698 1.1E-32 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 hmeg3_RS06585 0cc819e4ecb3f3edd0a7fc86d54b0643 808 Pfam PF00912 Transglycosylase 74 247 3.4E-65 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 SUPERFAMILY SSF81342 22 294 4.24E-97 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 PIRSF PIRSF038885 12 481 1.0E-148 T 28-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 SUPERFAMILY SSF81648 364 468 4.58E-12 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 SUPERFAMILY SSF81648 296 353 3.27E-9 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 Gene3D G3DSA:1.20.810.10 21 474 4.6E-160 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 Pfam PF00033 Cytochrome b/b6/petB 38 226 3.0E-67 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 hmeg3_RS03570 7303ac0de96e277c466091c942b7e8a7 482 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 292 455 1.7E-33 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 PIRSF PIRSF000110 2 484 1.9E-176 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 5 482 83.554 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 184 2.1E-57 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 140 153 6.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 325 351 6.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 234 250 6.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 216 233 6.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 192 6.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 Gene3D G3DSA:3.40.50.720 3 185 1.9E-61 T 28-03-2018 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 SUPERFAMILY SSF55347 174 481 8.83E-119 T 28-03-2018 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 174 180 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 6 482 6.4E-181 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 186 481 6.6E-119 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 Gene3D G3DSA:3.30.360.10 186 483 4.6E-133 T 28-03-2018 hmeg3_RS17860 74e0aa3b4779f40554ec7404b37aa891 488 SUPERFAMILY SSF51735 4 187 3.23E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20155 ecf694eb0122b5a432297f755b3d6d9e 155 Pfam PF02631 RecX family 36 145 1.5E-22 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 hmeg3_RS20155 ecf694eb0122b5a432297f755b3d6d9e 155 Hamap MF_01114 Regulatory protein RecX [recX]. 3 150 12.683 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 hmeg3_RS20155 ecf694eb0122b5a432297f755b3d6d9e 155 Gene3D G3DSA:1.10.10.10 55 93 2.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20155 ecf694eb0122b5a432297f755b3d6d9e 155 Gene3D G3DSA:1.10.10.10 101 149 2.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20155 ecf694eb0122b5a432297f755b3d6d9e 155 Gene3D G3DSA:1.10.10.10 6 53 1.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 191 4.7E-4 T 28-03-2018 hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 Gene3D G3DSA:3.40.50.720 47 250 1.3E-52 T 28-03-2018 hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 Gene3D G3DSA:3.40.50.720 1 46 1.2E-10 T 28-03-2018 hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 1.8E-55 T 28-03-2018 hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.9E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.9E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.9E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 SUPERFAMILY SSF51735 4 247 1.25E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 8.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06350 8cd9b0d5b04843ba54017f318878d1b6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 2.5E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 PIRSF PIRSF000077 2 108 7.9E-44 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 Gene3D G3DSA:3.40.30.10 1 107 2.3E-36 T 28-03-2018 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 PRINTS PR00421 Thioredoxin family signature 32 41 5.4E-10 T 28-03-2018 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 PRINTS PR00421 Thioredoxin family signature 72 83 5.4E-10 T 28-03-2018 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 PRINTS PR00421 Thioredoxin family signature 24 32 5.4E-10 T 28-03-2018 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 Pfam PF00085 Thioredoxin 5 106 6.1E-35 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 hmeg3_RS19530 0cd0922e50f6403a919d7a9487adaa90 108 SUPERFAMILY SSF52833 3 107 4.5E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 Gene3D G3DSA:3.30.565.10 213 364 4.8E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 SMART SM00388 145 210 1.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 Gene3D G3DSA:1.10.287.130 139 206 1.9E-14 T 28-03-2018 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 362 1.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 SMART SM00387 254 364 5.6E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 SUPERFAMILY SSF55874 199 363 4.85E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 SUPERFAMILY SSF52172 4 143 1.25E-30 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 319 6.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 361 6.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 6.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 SMART SM00448 5 119 1.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 Gene3D G3DSA:3.40.50.2300 2 138 7.7E-30 T 28-03-2018 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 207 6.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 Pfam PF00072 Response regulator receiver domain 8 118 2.5E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23475 ab302e210271c109e45ff517db88b34c 391 SUPERFAMILY SSF47384 132 207 1.35E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 SUPERFAMILY SSF53850 87 297 3.57E-22 T 28-03-2018 hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 Gene3D G3DSA:1.10.10.10 1 85 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 Gene3D G3DSA:3.40.190.10 87 182 1.4E-8 T 28-03-2018 hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 8.4E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 Gene3D G3DSA:3.40.190.10 183 269 1.3E-11 T 28-03-2018 hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 Pfam PF03466 LysR substrate binding domain 87 294 4.3E-25 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS22205 6a38e9a315aebdb834232c400d12000c 304 SUPERFAMILY SSF46785 5 84 2.31E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04960 47b1ffc9f343e8b4b572427526dc1032 283 SUPERFAMILY SSF161098 4 279 6.82E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04960 47b1ffc9f343e8b4b572427526dc1032 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 278 1.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04960 47b1ffc9f343e8b4b572427526dc1032 283 Gene3D G3DSA:1.10.3720.10 3 272 6.4E-32 T 28-03-2018 hmeg3_RS06480 6c06bd354cba3459853d1a01645d815b 427 SUPERFAMILY SSF111369 64 312 1.57E-83 T 28-03-2018 hmeg3_RS06480 6c06bd354cba3459853d1a01645d815b 427 Pfam PF00529 HlyD membrane-fusion protein of T1SS 287 372 4.6E-6 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS06480 6c06bd354cba3459853d1a01645d815b 427 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 54 383 5.0E-78 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS06480 6c06bd354cba3459853d1a01645d815b 427 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 305 3.1E-10 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS06480 6c06bd354cba3459853d1a01645d815b 427 Gene3D G3DSA:1.20.1600.10 67 330 2.1E-28 T 28-03-2018 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 SUPERFAMILY SSF47005 112 153 3.66E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 SUPERFAMILY SSF52777 185 414 4.45E-88 T 28-03-2018 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 185 413 3.4E-80 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Gene3D G3DSA:3.30.559.10 170 413 3.4E-89 T 28-03-2018 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Gene3D G3DSA:4.10.320.10 119 169 8.1E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Pfam PF00364 Biotin-requiring enzyme 5 77 4.1E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Pfam PF02817 e3 binding domain 117 150 2.0E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Gene3D G3DSA:3.90.1170.30 1 47 1.8E-13 T 28-03-2018 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 Gene3D G3DSA:2.40.50.100 48 118 1.0E-5 T 28-03-2018 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 414 4.8E-169 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 SUPERFAMILY SSF51230 2 95 2.75E-25 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS08785 5e437a27ee1a1440ede0188d0b2ddbf9 415 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 SUPERFAMILY SSF52096 27 284 1.85E-86 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 Gene3D G3DSA:3.90.226.10 14 290 1.1E-70 T 28-03-2018 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 37.726 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 4.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 4.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 4.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 4.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 4.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 Pfam PF01039 Carboxyl transferase domain 115 243 8.6E-16 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 hmeg3_RS17205 1617ea81f31a0146ad677ce9f0115517 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 1.9E-127 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 SUPERFAMILY SSF53901 8 237 2.45E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 Gene3D G3DSA:3.40.47.10 3 247 2.2E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 Gene3D G3DSA:3.40.47.10 262 376 1.4E-8 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 PIRSF PIRSF000429 5 393 1.2E-59 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 Pfam PF02803 Thiolase, C-terminal domain 261 364 1.6E-8 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 Pfam PF00108 Thiolase, N-terminal domain 21 189 9.2E-16 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS04875 caa022986c248facf32b3838b0d26cda 395 SUPERFAMILY SSF53901 249 381 2.98E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22270 6f3d852b30d46aa15b387e3873262c2b 345 Gene3D G3DSA:3.40.50.720 2 344 5.9E-53 T 28-03-2018 hmeg3_RS22270 6f3d852b30d46aa15b387e3873262c2b 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 246 3.5E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS22270 6f3d852b30d46aa15b387e3873262c2b 345 SUPERFAMILY SSF51735 3 334 4.03E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 Pfam PF07729 FCD domain 75 195 1.6E-18 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 SMART SM00895 75 197 1.4E-14 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 SUPERFAMILY SSF48008 71 197 2.62E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 5.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 SMART SM00345 7 65 9.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 Gene3D G3DSA:1.20.120.530 74 210 1.0E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 SUPERFAMILY SSF46785 3 82 1.42E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19305 88a8ce82438c369b4a7bd2b181c6d09c 259 Gene3D G3DSA:1.10.10.10 1 73 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 Gene3D G3DSA:1.20.1250.20 1 220 4.4E-34 T 28-03-2018 hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 PRINTS PR01035 Tetracycline resistance protein signature 122 143 1.9E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 PRINTS PR01035 Tetracycline resistance protein signature 33 49 1.9E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 PRINTS PR01035 Tetracycline resistance protein signature 152 174 1.9E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 Gene3D G3DSA:1.20.1250.20 221 407 4.2E-22 T 28-03-2018 hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 SUPERFAMILY SSF103473 20 406 6.1E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01590 0943b321ff66adc79f88b8314f03e858 410 Pfam PF07690 Major Facilitator Superfamily 28 254 4.2E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Gene3D G3DSA:3.40.50.80 199 331 5.8E-16 T 28-03-2018 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Pfam PF00557 Metallopeptidase family M24 352 507 2.7E-19 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 SUPERFAMILY SSF52343 205 324 5.89E-22 T 28-03-2018 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Gene3D G3DSA:3.90.230.10 347 560 5.5E-21 T 28-03-2018 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 SUPERFAMILY SSF63380 102 200 1.08E-18 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Pfam PF00175 Oxidoreductase NAD-binding domain 211 304 1.4E-8 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 82 2.1E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Gene3D G3DSA:3.10.20.30 1 98 2.5E-17 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Gene3D G3DSA:2.40.30.10 99 198 3.7E-18 T 28-03-2018 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 Pfam PF00970 Oxidoreductase FAD-binding domain 105 200 1.2E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 SUPERFAMILY SSF55920 350 556 1.44E-25 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS10750 2d088cfe91ad72b0986290d24f3a118f 576 SUPERFAMILY SSF54292 3 92 8.91E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 PRINTS PR01438 Universal stress protein signature 106 118 3.3E-22 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 PRINTS PR01438 Universal stress protein signature 2 20 3.3E-22 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 PRINTS PR01438 Universal stress protein signature 124 146 3.3E-22 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 PIRSF PIRSF006276 1 149 1.9E-19 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 Gene3D G3DSA:3.40.50.620 1 152 7.3E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 SUPERFAMILY SSF52402 1 146 3.35E-36 T 28-03-2018 hmeg3_RS10895 e07b1ff3626b203fce7ace7991a67bdc 152 Pfam PF00582 Universal stress protein family 1 146 4.6E-32 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS05315 ce39c0f960252038090e4dc6b0320683 307 SMART SM00342 219 302 9.2E-32 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS05315 ce39c0f960252038090e4dc6b0320683 307 Gene3D G3DSA:1.10.10.60 206 259 2.5E-17 T 28-03-2018 hmeg3_RS05315 ce39c0f960252038090e4dc6b0320683 307 Gene3D G3DSA:1.10.10.60 260 307 1.7E-16 T 28-03-2018 hmeg3_RS05315 ce39c0f960252038090e4dc6b0320683 307 SUPERFAMILY SSF46689 256 305 2.33E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05315 ce39c0f960252038090e4dc6b0320683 307 SUPERFAMILY SSF46689 205 252 1.32E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05315 ce39c0f960252038090e4dc6b0320683 307 Pfam PF12833 Helix-turn-helix domain 225 304 1.1E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14000 30c1855a9bfe5ba143f05819b28fcbfd 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.5E-8 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS14000 30c1855a9bfe5ba143f05819b28fcbfd 174 SUPERFAMILY SSF51161 4 169 6.38E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS14000 30c1855a9bfe5ba143f05819b28fcbfd 174 Gene3D G3DSA:2.160.10.10 1 174 1.8E-44 T 28-03-2018 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 TIGRFAM TIGR00067 glut_race: glutamate racemase 9 261 2.0E-54 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 Hamap MF_00258 Glutamate racemase [murI]. 7 266 33.665 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 73 81 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 Gene3D G3DSA:3.40.50.1860 116 274 3.4E-34 T 28-03-2018 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 SUPERFAMILY SSF53681 112 271 8.18E-28 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 Gene3D G3DSA:3.40.50.1860 23 115 1.5E-19 T 28-03-2018 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 223 1.3E-29 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 SUPERFAMILY SSF53681 8 110 3.86E-30 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS15900 620dce0428a4be4248061db78c781c87 277 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 185 195 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS19580 21944f761e786159686cb35aa147e516 190 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 4 172 32.755 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 hmeg3_RS19580 21944f761e786159686cb35aa147e516 190 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 8 166 9.8E-79 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 hmeg3_RS19580 21944f761e786159686cb35aa147e516 190 SUPERFAMILY SSF51182 4 173 1.6E-53 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS19580 21944f761e786159686cb35aa147e516 190 Gene3D G3DSA:2.60.120.10 9 174 1.7E-44 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS19580 21944f761e786159686cb35aa147e516 190 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 6 154 4.3E-46 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 hmeg3_RS03490 65d8e75476cd9e380123217413c4aab6 367 Pfam PF00155 Aminotransferase class I and II 34 351 1.0E-42 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS03490 65d8e75476cd9e380123217413c4aab6 367 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 358 54.035 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 hmeg3_RS03490 65d8e75476cd9e380123217413c4aab6 367 Gene3D G3DSA:3.40.640.10 55 249 5.9E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS03490 65d8e75476cd9e380123217413c4aab6 367 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 356 7.5E-95 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 hmeg3_RS03490 65d8e75476cd9e380123217413c4aab6 367 Gene3D G3DSA:3.90.1150.10 250 366 3.8E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS03490 65d8e75476cd9e380123217413c4aab6 367 SUPERFAMILY SSF53383 12 356 3.94E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 SUPERFAMILY SSF46557 3 78 2.22E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 Pfam PF03449 Transcription elongation factor, N-terminal 4 71 1.3E-29 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 PIRSF PIRSF006092 1 160 4.5E-48 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 Gene3D G3DSA:1.10.287.180 3 76 1.8E-29 T 28-03-2018 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 Gene3D G3DSA:3.10.50.30 80 160 6.1E-26 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 SUPERFAMILY SSF54534 85 159 1.57E-22 T 28-03-2018 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 158 31.172 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 157 1.3E-52 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 hmeg3_RS06530 9eedd6f2464ef82ccbf955a1bb3f484e 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 159 2.9E-28 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 hmeg3_RS03425 24142e9086a9f23659455a91328cd5ee 267 Gene3D G3DSA:3.40.50.300 1 248 1.1E-66 T 28-03-2018 hmeg3_RS03425 24142e9086a9f23659455a91328cd5ee 267 Pfam PF00005 ABC transporter 21 169 2.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03425 24142e9086a9f23659455a91328cd5ee 267 SUPERFAMILY SSF52540 4 233 1.08E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03425 24142e9086a9f23659455a91328cd5ee 267 SMART SM00382 29 226 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03425 24142e9086a9f23659455a91328cd5ee 267 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 298 732 3.6E-171 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 SMART SM00481 7 74 2.9E-22 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Pfam PF14579 Helix-hairpin-helix motif 808 900 2.1E-27 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Gene3D G3DSA:1.10.150.280 832 898 1.6E-9 T 28-03-2018 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 SUPERFAMILY SSF89550 6 268 1.28E-10 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1028 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Pfam PF01336 OB-fold nucleic acid binding domain 993 1069 3.2E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Pfam PF02811 PHP domain 8 178 8.6E-43 T 28-03-2018 IPR004013 PHP domain GO:0003824 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Gene3D G3DSA:2.40.50.140 974 1071 5.3E-15 T 28-03-2018 hmeg3_RS18925 a797b9fc8747c4431317da0569910d0e 1153 Gene3D G3DSA:3.20.20.140 3 253 6.2E-34 T 28-03-2018 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Gene3D G3DSA:2.20.25.90 12 73 6.6E-15 T 28-03-2018 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Gene3D G3DSA:3.40.228.10 171 267 3.9E-24 T 28-03-2018 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 433 450 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Pfam PF00384 Molybdopterin oxidoreductase 72 488 3.7E-55 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Gene3D G3DSA:3.40.50.740 74 170 1.8E-17 T 28-03-2018 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 17 69 1.9E-10 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 SMART SM00926 14 69 1.7E-15 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 SUPERFAMILY SSF50692 542 702 2.49E-36 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Pfam PF01568 Molydopterin dinucleotide binding domain 588 696 1.8E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Gene3D G3DSA:3.40.50.740 268 572 6.4E-42 T 28-03-2018 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 SUPERFAMILY SSF53706 17 589 2.22E-166 T 28-03-2018 hmeg3_RS04620 d307d451295992ef37d0951c7ad9f5bd 708 Gene3D G3DSA:2.40.40.20 573 708 1.6E-31 T 28-03-2018 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 507 7.9E-245 T 28-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 Gene3D G3DSA:3.40.50.1100 156 330 2.0E-36 T 28-03-2018 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 294 6.6E-75 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 Gene3D G3DSA:3.40.1020.10 333 508 2.5E-75 T 28-03-2018 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 SUPERFAMILY SSF55021 414 507 4.35E-28 T 28-03-2018 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 Gene3D G3DSA:3.40.50.1100 7 155 1.3E-42 T 28-03-2018 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 325 413 1.2E-26 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 423 507 4.8E-23 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 hmeg3_RS04360 9391c02caf9be0be00a85c5ebb6c7093 508 SUPERFAMILY SSF53686 4 361 1.7E-98 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS20960 129ae436d40f3b178b3564f9b114e05d 257 SUPERFAMILY SSF52096 3 257 5.87E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS20960 129ae436d40f3b178b3564f9b114e05d 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 256 4.4E-57 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS20960 129ae436d40f3b178b3564f9b114e05d 257 Gene3D G3DSA:1.10.12.10 214 257 1.0E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS20960 129ae436d40f3b178b3564f9b114e05d 257 Gene3D G3DSA:3.90.226.10 4 213 1.2E-61 T 28-03-2018 hmeg3_RS20960 129ae436d40f3b178b3564f9b114e05d 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 Gene3D G3DSA:2.40.30.10 189 273 2.7E-22 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 396 1.1E-116 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 SUPERFAMILY SSF51905 341 398 1.85E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 SUPERFAMILY SSF51905 1 189 1.85E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 Pfam PF03486 HI0933-like protein 5 396 4.2E-139 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 Gene3D G3DSA:3.50.50.60 1 181 4.9E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 SUPERFAMILY SSF160996 190 344 2.35E-38 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 Gene3D G3DSA:1.10.8.260 274 325 1.6E-15 T 28-03-2018 IPR023166 HI0933 insert-like domain hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 4.5E-6 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 4.5E-6 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.5E-6 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.1E-6 T 28-03-2018 hmeg3_RS19505 23e7df0b8accf6579cc736fcfa281f31 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 2.1E-6 T 28-03-2018 hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 Pfam PF00593 TonB dependent receptor 264 720 6.4E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 722 9.0E-111 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 Gene3D G3DSA:2.170.130.10 26 175 2.4E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 SUPERFAMILY SSF56935 27 722 1.7E-100 T 28-03-2018 hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 Gene3D G3DSA:2.40.170.20 176 722 8.4E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 705 722 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site hmeg3_RS05765 adf8214d0ea450e2d52cd32ba7aba010 722 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 163 9.7E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 405 560 2.9E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Pfam PF00672 HAMP domain 292 339 6.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 SUPERFAMILY SSF103190 111 174 3.88E-10 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Gene3D G3DSA:3.30.450.20 154 260 7.6E-20 T 28-03-2018 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Gene3D G3DSA:3.30.450.20 24 153 1.5E-19 T 28-03-2018 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Gene3D G3DSA:1.10.287.950 261 397 4.1E-10 T 28-03-2018 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 SUPERFAMILY SSF58104 313 594 7.46E-75 T 28-03-2018 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 SMART SM00304 291 345 4.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 SMART SM00283 346 593 5.7E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Gene3D G3DSA:1.10.287.950 398 597 3.6E-49 T 28-03-2018 hmeg3_RS08045 74e95b251132ec1d32c99d3424a2dcba 657 Pfam PF02743 Cache domain 38 253 3.9E-25 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 Gene3D G3DSA:3.50.50.60 239 332 0.15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 Gene3D G3DSA:3.30.950.10 123 238 4.4E-40 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 SUPERFAMILY SSF53790 1 244 6.54E-48 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 242 3.7E-85 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 262 511 1.4E-72 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 Gene3D G3DSA:3.40.50.2300 333 523 2.0E-10 T 28-03-2018 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 Gene3D G3DSA:3.40.1010.10 2 122 1.9E-27 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 261 510 5.5E-58 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 hmeg3_RS12400 2c76954514f63ae4065d4df52a03e7b4 525 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 210 7.1E-34 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 Gene3D G3DSA:1.10.357.10 58 190 6.0E-19 T 28-03-2018 hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 SUPERFAMILY SSF48498 78 189 1.92E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 SUPERFAMILY SSF46689 4 71 1.95E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 Gene3D G3DSA:1.10.10.60 2 57 2.5E-10 T 28-03-2018 hmeg3_RS06395 487de06d22848f673e3e933747cc9859 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 Pfam PF13378 Enolase C-terminal domain-like 174 387 7.5E-51 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 32 135 1.1E-9 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 Gene3D G3DSA:3.30.390.10 1 142 3.6E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 Gene3D G3DSA:3.20.20.120 143 395 6.9E-58 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 SUPERFAMILY SSF54826 1 135 2.19E-26 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 SUPERFAMILY SSF51604 135 396 9.69E-72 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS13225 11ae894a55c8ffa81498d414237a9226 424 SMART SM00922 171 265 1.7E-22 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 216 454 6.4E-78 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 PRINTS PR00084 Mannitol dehydrogenase signature 178 191 8.5E-20 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 PRINTS PR00084 Mannitol dehydrogenase signature 29 39 8.5E-20 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 PRINTS PR00084 Mannitol dehydrogenase signature 217 230 8.5E-20 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 PRINTS PR00084 Mannitol dehydrogenase signature 247 262 8.5E-20 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 Gene3D G3DSA:1.10.1040.10 281 484 1.0E-66 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 SUPERFAMILY SSF48179 284 482 2.01E-58 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 SUPERFAMILY SSF51735 1 281 1.38E-100 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 Gene3D G3DSA:3.40.50.720 1 280 9.8E-117 T 28-03-2018 hmeg3_RS14425 a8362c3a24bc1beb69e6497ab8f05f46 485 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 28 187 2.7E-45 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 hmeg3_RS04380 a46010165f8e7e32006a6ef6abeaadc8 144 SUPERFAMILY SSF54197 4 138 2.94E-37 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 hmeg3_RS04380 a46010165f8e7e32006a6ef6abeaadc8 144 PIRSF PIRSF000714 4 143 1.8E-42 T 28-03-2018 IPR026026 Histidine triad hydrolase, Hint-type hmeg3_RS04380 a46010165f8e7e32006a6ef6abeaadc8 144 Gene3D G3DSA:3.30.428.10 3 144 2.8E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 hmeg3_RS04380 a46010165f8e7e32006a6ef6abeaadc8 144 Pfam PF01230 HIT domain 16 100 3.6E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 PIRSF PIRSF000094 1 258 1.3E-111 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 SUPERFAMILY SSF51735 5 252 8.74E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 Gene3D G3DSA:3.40.50.720 1 256 1.0E-36 T 28-03-2018 hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06985 8fd35adb290c4495561936171dbe128f 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 252 1.1E-83 T 28-03-2018 hmeg3_RS04940 8b178ac42c42783f00c71fe83b7ea3e1 247 Gene3D G3DSA:2.70.70.10 83 245 2.1E-34 T 28-03-2018 hmeg3_RS04940 8b178ac42c42783f00c71fe83b7ea3e1 247 Gene3D G3DSA:3.10.350.10 22 77 1.5E-13 T 28-03-2018 hmeg3_RS04940 8b178ac42c42783f00c71fe83b7ea3e1 247 SUPERFAMILY SSF51261 29 242 2.62E-41 T 28-03-2018 IPR011055 Duplicated hybrid motif hmeg3_RS04940 8b178ac42c42783f00c71fe83b7ea3e1 247 Pfam PF01551 Peptidase family M23 146 238 4.8E-28 T 28-03-2018 IPR016047 Peptidase M23 hmeg3_RS04940 8b178ac42c42783f00c71fe83b7ea3e1 247 Pfam PF01476 LysM domain 29 71 1.0E-10 T 28-03-2018 IPR018392 LysM domain hmeg3_RS04940 8b178ac42c42783f00c71fe83b7ea3e1 247 SMART SM00257 28 72 4.6E-10 T 28-03-2018 IPR018392 LysM domain hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 107 119 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 36 355 1.4E-53 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 SUPERFAMILY SSF53335 33 360 3.32E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 Gene3D G3DSA:3.40.50.150 33 203 2.1E-49 T 28-03-2018 hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 Pfam PF00145 C-5 cytosine-specific DNA methylase 35 359 2.2E-62 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 Gene3D G3DSA:3.90.120.10 204 346 2.7E-23 T 28-03-2018 hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 146 160 2.5E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 193 206 2.5E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 hmeg3_RS24280 69351d1c0682fcb6a8cf2a165ec35c8e 383 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 34 50 2.5E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 hmeg3_RS07285 edac54bdb88da18a227e4a5064d432d4 460 Pfam PF08666 SAF domain 362 426 2.2E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS07285 edac54bdb88da18a227e4a5064d432d4 460 Gene3D G3DSA:3.40.50.720 11 207 1.8E-24 T 28-03-2018 hmeg3_RS07285 edac54bdb88da18a227e4a5064d432d4 460 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 24 134 8.6E-6 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 hmeg3_RS07285 edac54bdb88da18a227e4a5064d432d4 460 SUPERFAMILY SSF51735 15 151 2.81E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS07285 edac54bdb88da18a227e4a5064d432d4 460 SMART SM00858 362 427 1.6E-5 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS24030 8f54aae7304e69893ffa704531d6bb5b 180 SUPERFAMILY SSF69118 2 175 1.03E-43 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS24030 8f54aae7304e69893ffa704531d6bb5b 180 Gene3D G3DSA:1.20.1290.10 57 176 2.1E-19 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS24030 8f54aae7304e69893ffa704531d6bb5b 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 54 109 7.0E-14 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS24030 8f54aae7304e69893ffa704531d6bb5b 180 Gene3D G3DSA:1.20.5.810 12 53 2.3E-12 T 28-03-2018 hmeg3_RS24030 8f54aae7304e69893ffa704531d6bb5b 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 56 100 1.3E-13 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 Gene3D G3DSA:3.40.50.620 115 235 4.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 Gene3D G3DSA:3.40.50.620 8 114 7.3E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 25 36 1.7E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 208 1.7E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 11 23 1.7E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 40 53 1.7E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 184 194 1.7E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 SUPERFAMILY SSF52374 8 278 6.14E-78 T 28-03-2018 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 252 6.4E-39 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 8 297 41.273 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 hmeg3_RS18945 8adab79bcf0e05d9e43abd82de92827b 298 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 8 277 5.8E-113 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 SUPERFAMILY SSF53901 263 385 7.82E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 SUPERFAMILY SSF53901 5 232 4.78E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 78 96 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 Pfam PF00108 Thiolase, N-terminal domain 5 190 5.7E-19 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 Pfam PF02803 Thiolase, C-terminal domain 273 372 3.1E-11 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 PIRSF PIRSF000429 1 396 8.8E-63 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 Gene3D G3DSA:3.40.47.10 2 242 9.1E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20940 73a1e8457cf800da79cc8f4f62c8ac7c 397 Gene3D G3DSA:3.40.47.10 246 395 6.9E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 SUPERFAMILY SSF46785 12 124 1.51E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 4.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 4.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 4.5E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 Pfam PF03466 LysR substrate binding domain 100 307 5.9E-27 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 Gene3D G3DSA:1.10.10.10 9 96 3.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 SUPERFAMILY SSF53850 100 311 2.64E-28 T 28-03-2018 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 Gene3D G3DSA:3.40.190.10 195 279 2.2E-13 T 28-03-2018 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 Gene3D G3DSA:3.40.190.10 101 194 1.2E-17 T 28-03-2018 hmeg3_RS18975 53113a1323554d8f6724bc44c5082480 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 1.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13575 710f9fdaf007fd9e6a946e000c49d2dd 214 SUPERFAMILY SSF161098 116 208 9.16E-5 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS13575 710f9fdaf007fd9e6a946e000c49d2dd 214 PIRSF PIRSF006324 1 209 1.6E-51 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS13575 710f9fdaf007fd9e6a946e000c49d2dd 214 Pfam PF01810 LysE type translocator 16 206 4.8E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS16175 38bd966852ad88436d26d282d8f95b6c 255 SUPERFAMILY SSF53901 37 177 1.44E-8 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16175 38bd966852ad88436d26d282d8f95b6c 255 Gene3D G3DSA:3.40.47.10 7 218 9.4E-7 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16175 38bd966852ad88436d26d282d8f95b6c 255 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 26 252 1.8E-68 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal hmeg3_RS02730 af01a44dc529424ce337c1c5fe2a55af 165 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 75 85 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 hmeg3_RS02730 af01a44dc529424ce337c1c5fe2a55af 165 SUPERFAMILY SSF53774 3 154 2.22E-33 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS02730 af01a44dc529424ce337c1c5fe2a55af 165 Gene3D G3DSA:3.40.50.1170 1 157 3.6E-28 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 hmeg3_RS02730 af01a44dc529424ce337c1c5fe2a55af 165 PRINTS PR00139 Asparaginase/glutaminase family signature 74 92 1.9E-7 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS02730 af01a44dc529424ce337c1c5fe2a55af 165 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 1.9E-7 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS02730 af01a44dc529424ce337c1c5fe2a55af 165 Pfam PF00710 Asparaginase, N-terminal 4 153 1.1E-23 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 SUPERFAMILY SSF47648 4 71 1.83E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 68 1.6E-11 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 36.302 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 11 336 1.2E-123 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 SUPERFAMILY SSF52418 78 340 2.09E-94 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 Gene3D G3DSA:1.20.970.10 1 72 3.9E-16 T 28-03-2018 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 Pfam PF00591 Glycosyl transferase family, a/b domain 78 328 2.2E-89 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS04440 fb5e54a6e027800f06e8b68bb9710ea6 345 Gene3D G3DSA:3.40.1030.10 73 345 1.3E-102 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 SMART SM01086 344 443 3.7E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Gene3D G3DSA:1.10.8.60 343 452 1.9E-24 T 28-03-2018 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 3 452 2.2E-203 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Gene3D G3DSA:1.10.8.10 211 253 3.8E-15 T 28-03-2018 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Pfam PF07724 AAA domain (Cdc48 subfamily) 194 338 1.2E-41 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 96 3.3E-6 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 344 413 1.4E-4 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Gene3D G3DSA:1.10.8.10 124 210 3.2E-29 T 28-03-2018 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Gene3D G3DSA:3.40.50.300 1 123 2.7E-13 T 28-03-2018 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 452 42.412 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 SMART SM00382 48 341 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22480 31de3bb5345119f42bef72b6cac7679c 452 SUPERFAMILY SSF52540 2 449 4.04E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11150 ea95940297b5b05a794aabc0f853cdc4 168 Pfam PF03928 Haem-degrading 41 163 2.0E-30 T 28-03-2018 IPR005624 Haem-degrading hmeg3_RS11150 ea95940297b5b05a794aabc0f853cdc4 168 SUPERFAMILY SSF143744 36 166 3.4E-34 T 28-03-2018 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 Pfam PF01479 S4 domain 53 98 1.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 169 183 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 SUPERFAMILY SSF55174 52 102 1.68E-8 T 28-03-2018 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 Gene3D G3DSA:3.10.290.10 37 109 6.1E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 SUPERFAMILY SSF55120 112 344 3.29E-72 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 Pfam PF00849 RNA pseudouridylate synthase 127 281 1.2E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 50 337 5.1E-86 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 Gene3D G3DSA:3.30.2350.10 117 342 9.0E-69 T 28-03-2018 hmeg3_RS08610 0b5c13c5912b5366f3e10039a4fc8d47 352 SMART SM00363 52 106 2.1E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 142 1.0E-44 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 Pfam PF01220 Dehydroquinase class II 5 141 1.3E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 SUPERFAMILY SSF52304 4 143 7.33E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 145 70.209 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 PIRSF PIRSF001399 1 145 1.5E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 Gene3D G3DSA:3.40.50.9100 3 145 1.6E-65 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS21750 eb0779c73b0bafd43dff0fe571f56a3d 145 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 143 1.5E-58 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS22245 991a03f430b082763d89d2a5a8b590da 754 SMART SM01080 36 398 1.0E-70 T 28-03-2018 IPR007890 CHASE2 hmeg3_RS22245 991a03f430b082763d89d2a5a8b590da 754 Gene3D G3DSA:3.30.70.1230 490 684 1.1E-45 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 hmeg3_RS22245 991a03f430b082763d89d2a5a8b590da 754 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 496 672 1.7E-31 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 hmeg3_RS22245 991a03f430b082763d89d2a5a8b590da 754 SUPERFAMILY SSF55073 492 678 1.04E-56 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS22245 991a03f430b082763d89d2a5a8b590da 754 Pfam PF05226 CHASE2 domain 26 397 4.5E-55 T 28-03-2018 IPR007890 CHASE2 hmeg3_RS22245 991a03f430b082763d89d2a5a8b590da 754 SMART SM00044 458 659 1.4E-17 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SUPERFAMILY SSF143517 999 1150 7.45E-42 T 28-03-2018 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SMART SM01058 484 581 2.8E-49 T 28-03-2018 IPR003711 CarD-like/TRCF domain hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Pfam PF02559 CarD-like/TRCF domain 485 580 2.1E-26 T 28-03-2018 IPR003711 CarD-like/TRCF domain hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Gene3D G3DSA:3.40.50.300 793 961 1.6E-26 T 28-03-2018 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SUPERFAMILY SSF52540 361 469 8.41E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Pfam PF00271 Helicase conserved C-terminal domain 809 914 2.0E-17 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 34 1112 27.88 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SUPERFAMILY SSF141259 477 553 6.02E-23 T 28-03-2018 IPR003711 CarD-like/TRCF domain hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Gene3D G3DSA:3.30.2060.10 142 187 8.2E-5 T 28-03-2018 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Gene3D G3DSA:3.40.50.300 395 791 6.0E-38 T 28-03-2018 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SMART SM00490 831 915 4.5E-17 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SUPERFAMILY SSF52540 788 995 2.96E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SMART SM00982 1013 1113 6.6E-49 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 159 1086 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Pfam PF00270 DEAD/DEAH box helicase 610 767 7.9E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SUPERFAMILY SSF52540 7 351 2.81E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SMART SM00487 605 795 7.7E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 SUPERFAMILY SSF52540 528 788 4.35E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08520 1260b5332362b5ec76c6c4ec3843af11 1151 Pfam PF03461 TRCF domain 1014 1106 3.3E-26 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 hmeg3_RS07695 903307c08d38b9c92a8487f1d4c177f4 288 SUPERFAMILY SSF53474 18 278 1.82E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07695 903307c08d38b9c92a8487f1d4c177f4 288 Gene3D G3DSA:3.40.50.1820 3 286 4.6E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07695 903307c08d38b9c92a8487f1d4c177f4 288 Pfam PF12697 Alpha/beta hydrolase family 34 279 4.1E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS07695 903307c08d38b9c92a8487f1d4c177f4 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS07695 903307c08d38b9c92a8487f1d4c177f4 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS07695 903307c08d38b9c92a8487f1d4c177f4 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 233 247 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS16135 84b60f2c3add5bc0e9fc0eac679ed1e4 547 Gene3D G3DSA:1.20.1250.20 251 489 5.6E-20 T 28-03-2018 hmeg3_RS16135 84b60f2c3add5bc0e9fc0eac679ed1e4 547 Pfam PF07690 Major Facilitator Superfamily 28 428 2.1E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS16135 84b60f2c3add5bc0e9fc0eac679ed1e4 547 Gene3D G3DSA:1.20.1250.20 7 242 4.0E-19 T 28-03-2018 hmeg3_RS16135 84b60f2c3add5bc0e9fc0eac679ed1e4 547 SUPERFAMILY SSF103473 15 476 1.07E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 SUPERFAMILY SSF54862 458 558 7.38E-29 T 28-03-2018 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 454 556 1.7E-50 T 28-03-2018 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 2.6E-5 T 28-03-2018 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 376 2.6E-5 T 28-03-2018 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 Gene3D G3DSA:3.50.50.60 4 395 2.3E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 SUPERFAMILY SSF51905 317 456 3.41E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 SUPERFAMILY SSF51905 15 220 3.41E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 Pfam PF13450 NAD(P)-binding Rossmann-like domain 23 71 6.9E-6 T 28-03-2018 hmeg3_RS13700 8af07bf25659f92fcbd701f5ae517f77 558 SUPERFAMILY SSF54373 221 316 2.9E-38 T 28-03-2018 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 Gene3D G3DSA:3.30.160.20 209 291 2.0E-33 T 28-03-2018 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 2.1E-163 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 Gene3D G3DSA:1.20.58.410 4 94 9.4E-17 T 28-03-2018 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 40.642 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 Pfam PF00472 RF-1 domain 211 321 2.3E-42 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 Pfam PF03462 PCRF domain 13 203 8.2E-72 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 SUPERFAMILY SSF75620 12 353 2.62E-137 T 28-03-2018 hmeg3_RS02945 7fd158595eaf8f07f0f6af15b3568e64 360 SMART SM00937 63 178 4.1E-66 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 SUPERFAMILY SSF54292 2 78 3.54E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 63 1.5E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 Gene3D G3DSA:1.10.150.120 75 154 6.1E-32 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 Pfam PF01799 [2Fe-2S] binding domain 73 145 4.7E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 Gene3D G3DSA:3.10.20.30 1 74 5.2E-26 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS22310 d98241ffff56d9f06265f9c30a91cede 154 SUPERFAMILY SSF47741 73 152 3.66E-32 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS03035 ad6d7547256990b414b5e3310fab1d6d 310 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 7 307 2.0E-161 T 28-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 hmeg3_RS03035 ad6d7547256990b414b5e3310fab1d6d 310 Pfam PF01522 Polysaccharide deacetylase 77 176 9.8E-11 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 hmeg3_RS03035 ad6d7547256990b414b5e3310fab1d6d 310 SUPERFAMILY SSF88713 6 308 1.17E-93 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS03035 ad6d7547256990b414b5e3310fab1d6d 310 Gene3D G3DSA:3.20.20.370 3 310 2.6E-64 T 28-03-2018 hmeg3_RS13120 90313d16f7eae004a9654544d74e1f1d 97 Pfam PF03795 YCII-related domain 1 83 2.8E-12 T 28-03-2018 IPR005545 YCII-related hmeg3_RS13120 90313d16f7eae004a9654544d74e1f1d 97 SUPERFAMILY SSF54909 1 85 8.85E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS13120 90313d16f7eae004a9654544d74e1f1d 97 Gene3D G3DSA:3.30.70.1060 1 86 1.9E-18 T 28-03-2018 hmeg3_RS01130 8c3e37d05f3bec580a80d32e8f60f8f9 261 Gene3D G3DSA:1.10.12.10 204 245 8.5E-19 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS01130 8c3e37d05f3bec580a80d32e8f60f8f9 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 hmeg3_RS01130 8c3e37d05f3bec580a80d32e8f60f8f9 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 238 2.0E-35 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS01130 8c3e37d05f3bec580a80d32e8f60f8f9 261 SUPERFAMILY SSF52096 7 252 7.78E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS01130 8c3e37d05f3bec580a80d32e8f60f8f9 261 Gene3D G3DSA:3.90.226.10 1 201 9.4E-53 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 SUPERFAMILY SSF51230 2 96 1.33E-24 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Gene3D G3DSA:3.40.50.720 291 468 1.7E-30 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 166 176 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Gene3D G3DSA:2.40.50.100 13 63 2.1E-14 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 407 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 180 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 275 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 436 443 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 471 492 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 536 551 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 558 578 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 154 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 326 2.4E-69 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 475 583 2.1E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 SUPERFAMILY SSF55424 471 594 2.06E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 SUPERFAMILY SSF51905 128 466 4.63E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Pfam PF00364 Biotin-requiring enzyme 5 74 8.0E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 132 456 1.5E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PIRSF PIRSF000350 31 594 5.3E-82 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Gene3D G3DSA:3.30.390.30 469 591 1.0E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Gene3D G3DSA:3.90.1170.30 64 100 2.9E-5 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 131 587 1.8E-141 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 152 3.9E-39 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 392 408 3.9E-39 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 281 3.9E-39 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 421 443 3.9E-39 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 319 3.9E-39 T 28-03-2018 hmeg3_RS17560 87db218406887f83fdeff45719255cc6 600 Gene3D G3DSA:3.50.50.60 128 290 2.1E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS06360 2665d0cde90d3576947937e648f0c6e6 229 Gene3D G3DSA:1.10.357.10 77 229 3.0E-23 T 28-03-2018 hmeg3_RS06360 2665d0cde90d3576947937e648f0c6e6 229 SUPERFAMILY SSF46689 8 72 5.13E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS06360 2665d0cde90d3576947937e648f0c6e6 229 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 222 2.7E-5 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 hmeg3_RS06360 2665d0cde90d3576947937e648f0c6e6 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 4.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS06360 2665d0cde90d3576947937e648f0c6e6 229 Gene3D G3DSA:1.10.10.60 1 66 6.7E-15 T 28-03-2018 hmeg3_RS06360 2665d0cde90d3576947937e648f0c6e6 229 SUPERFAMILY SSF48498 80 223 3.56E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 Gene3D G3DSA:2.40.160.10 20 371 3.1E-59 T 28-03-2018 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 SUPERFAMILY SSF56935 32 371 1.19E-67 T 28-03-2018 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 317 334 2.8E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 65 76 2.8E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 109 119 2.8E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 PRINTS PR00184 Neisseria sp. porin signature 67 92 2.4E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 PRINTS PR00184 Neisseria sp. porin signature 314 338 2.4E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19310 327995befa629a25c8a9ca9595baf44a 371 Pfam PF13609 Gram-negative porin 19 342 1.7E-44 T 28-03-2018 hmeg3_RS17175 fa867befa6d5b85957c3d50d8eb3b69b 198 Gene3D G3DSA:3.40.50.450 1 195 1.9E-58 T 28-03-2018 hmeg3_RS17175 fa867befa6d5b85957c3d50d8eb3b69b 198 Pfam PF03641 Possible lysine decarboxylase 46 174 1.0E-40 T 28-03-2018 IPR031100 LOG family hmeg3_RS17175 fa867befa6d5b85957c3d50d8eb3b69b 198 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 6.7E-60 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG hmeg3_RS17175 fa867befa6d5b85957c3d50d8eb3b69b 198 SUPERFAMILY SSF102405 1 179 1.36E-59 T 28-03-2018 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 Gene3D G3DSA:1.10.10.10 2 66 4.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 34 52 5.2E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 20 34 5.2E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 SUPERFAMILY SSF46785 2 73 4.08E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 Pfam PF00455 DeoR C terminal sensor domain 70 228 9.0E-41 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 SMART SM01134 68 229 5.5E-52 T 28-03-2018 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 Pfam PF08220 DeoR-like helix-turn-helix domain 2 55 1.2E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 SMART SM00420 2 54 1.4E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 SUPERFAMILY SSF100950 69 228 3.39E-22 T 28-03-2018 hmeg3_RS10980 e918e6b4f4d898d1f459ea2c6687e227 271 Gene3D G3DSA:3.40.50.1360 67 232 4.9E-33 T 28-03-2018 hmeg3_RS06370 c5762b174299697739a842dcd8d4c874 128 Gene3D G3DSA:3.10.129.10 1 127 1.6E-16 T 28-03-2018 hmeg3_RS06370 c5762b174299697739a842dcd8d4c874 128 Pfam PF13279 Thioesterase-like superfamily 8 123 1.6E-6 T 28-03-2018 hmeg3_RS06370 c5762b174299697739a842dcd8d4c874 128 SUPERFAMILY SSF54637 1 116 2.09E-21 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 Pfam PF09349 OHCU decarboxylase 16 171 3.1E-41 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 Pfam PF01546 Peptidase family M20/M25/M40 252 584 2.2E-23 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 17 174 1.5E-56 T 28-03-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 SUPERFAMILY SSF55031 388 504 6.63E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 Gene3D G3DSA:3.40.630.10 168 419 2.6E-34 T 28-03-2018 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 Gene3D G3DSA:3.40.630.10 420 589 3.1E-22 T 28-03-2018 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 186 581 3.5E-110 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 Pfam PF07687 Peptidase dimerisation domain 394 488 6.7E-5 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 SUPERFAMILY SSF158694 15 176 2.62E-47 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 Gene3D G3DSA:1.10.3330.10 2 167 2.3E-49 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 SUPERFAMILY SSF53187 186 398 2.34E-71 T 28-03-2018 hmeg3_RS17000 a5790a8bc3a06bcfa13ac338c53e9cb8 589 SUPERFAMILY SSF53187 512 585 2.34E-71 T 28-03-2018 hmeg3_RS16995 a8ae5c0a80539ee83e8114973bf3f867 467 TIGRFAM TIGR03173 pbuX: xanthine permease 23 446 1.7E-165 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 hmeg3_RS16995 a8ae5c0a80539ee83e8114973bf3f867 467 Pfam PF00860 Permease family 19 412 2.6E-103 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS16995 a8ae5c0a80539ee83e8114973bf3f867 467 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 14 443 1.6E-121 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 hmeg3_RS16995 a8ae5c0a80539ee83e8114973bf3f867 467 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 360 380 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 Gene3D G3DSA:3.40.50.720 1 158 5.5E-47 T 28-03-2018 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 339 41.501 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 SMART SM00859 3 141 4.5E-60 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 SUPERFAMILY SSF51735 2 173 9.45E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 141 1.0E-37 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 SUPERFAMILY SSF55347 149 313 1.9E-52 T 28-03-2018 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 316 5.8E-20 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 345 4.6E-130 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS04720 6bfd92890de1d15d4b3e961565ad27b9 345 Gene3D G3DSA:3.30.360.10 159 313 5.0E-57 T 28-03-2018 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 SUPERFAMILY SSF53850 96 297 2.17E-40 T 28-03-2018 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 Gene3D G3DSA:1.10.10.10 7 89 9.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 Pfam PF03466 LysR substrate binding domain 94 295 1.5E-40 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 Gene3D G3DSA:3.40.190.10 181 266 2.2E-17 T 28-03-2018 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 2.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.2E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.2E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.2E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 Gene3D G3DSA:3.40.190.10 95 180 6.6E-22 T 28-03-2018 hmeg3_RS22395 5d49adadaa69a4a50f287cf3a4dcc451 302 SUPERFAMILY SSF46785 7 85 3.03E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16190 8bbc02afb8511e8bc6076afc4f2c40f5 92 SUPERFAMILY SSF47336 6 88 2.75E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS16190 8bbc02afb8511e8bc6076afc4f2c40f5 92 Gene3D G3DSA:1.10.1200.10 1 92 1.1E-17 T 28-03-2018 hmeg3_RS16190 8bbc02afb8511e8bc6076afc4f2c40f5 92 Pfam PF00550 Phosphopantetheine attachment site 16 81 2.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS14015 70a510e2bd16f6b9f9ab4f66cd33efbe 257 SUPERFAMILY SSF75217 12 171 5.82E-34 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS14015 70a510e2bd16f6b9f9ab4f66cd33efbe 257 Pfam PF00588 SpoU rRNA Methylase family 14 165 1.5E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 hmeg3_RS14015 70a510e2bd16f6b9f9ab4f66cd33efbe 257 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 12 246 6.7E-65 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 hmeg3_RS14015 70a510e2bd16f6b9f9ab4f66cd33efbe 257 Gene3D G3DSA:3.40.1280.10 2 176 2.1E-41 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS14015 70a510e2bd16f6b9f9ab4f66cd33efbe 257 PIRSF PIRSF004808 9 254 5.0E-70 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 hmeg3_RS11640 7220a4901d4ba8562255ff9ec3d9c9be 255 Pfam PF00975 Thioesterase domain 3 224 2.4E-39 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 hmeg3_RS11640 7220a4901d4ba8562255ff9ec3d9c9be 255 Gene3D G3DSA:3.40.50.1820 2 230 2.9E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11640 7220a4901d4ba8562255ff9ec3d9c9be 255 SUPERFAMILY SSF53474 3 227 1.89E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 Gene3D G3DSA:1.10.10.10 5 84 2.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 82 5.8E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 SMART SM00895 93 218 1.3E-16 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 Pfam PF07729 FCD domain 93 216 3.9E-17 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 SUPERFAMILY SSF48008 89 218 3.14E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 SUPERFAMILY SSF46785 22 92 1.25E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 SMART SM00345 25 83 1.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS19165 a3241583801f1f5c2af566169269eee1 243 Gene3D G3DSA:1.20.120.530 85 229 3.8E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS11670 2d645cd0f738947e5330837cf6b07cbd 734 Gene3D G3DSA:2.40.170.20 202 734 2.0E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS11670 2d645cd0f738947e5330837cf6b07cbd 734 SUPERFAMILY SSF56935 39 717 3.66E-129 T 28-03-2018 hmeg3_RS11670 2d645cd0f738947e5330837cf6b07cbd 734 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 86 724 1.4E-118 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS11670 2d645cd0f738947e5330837cf6b07cbd 734 Pfam PF00593 TonB dependent receptor 271 711 5.1E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS11670 2d645cd0f738947e5330837cf6b07cbd 734 Gene3D G3DSA:2.170.130.10 39 201 1.3E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS11670 2d645cd0f738947e5330837cf6b07cbd 734 Pfam PF07715 TonB-dependent Receptor Plug Domain 85 189 8.1E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 Pfam PF02938 GAD domain 311 409 8.8E-27 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 SUPERFAMILY SSF55261 294 419 5.23E-43 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 567 1.7E-106 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 Gene3D G3DSA:2.40.50.140 2 110 1.7E-26 T 28-03-2018 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 591 2.5E-239 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 Gene3D G3DSA:3.30.930.10 116 566 1.4E-97 T 28-03-2018 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 Pfam PF01336 OB-fold nucleic acid binding domain 20 104 1.5E-18 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 SUPERFAMILY SSF55681 113 295 3.02E-105 T 28-03-2018 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 SUPERFAMILY SSF55681 433 594 3.02E-105 T 28-03-2018 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 593 33.394 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 SUPERFAMILY SSF50249 3 107 2.48E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 527 541 3.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 3.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 483 499 3.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS22410 ee3bb702abe53876947c6094d7f79949 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 3.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS11290 ea9ef58f174e99bfdf6229065bee102b 144 Pfam PF00072 Response regulator receiver domain 23 129 1.6E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11290 ea9ef58f174e99bfdf6229065bee102b 144 SMART SM00448 21 129 3.0E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11290 ea9ef58f174e99bfdf6229065bee102b 144 SUPERFAMILY SSF52172 19 134 4.41E-26 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11290 ea9ef58f174e99bfdf6229065bee102b 144 Gene3D G3DSA:3.40.50.2300 12 143 3.3E-26 T 28-03-2018 hmeg3_RS01980 a832e533f9e6914386bd03eb4123d8b3 355 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 322 2.0E-101 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01980 a832e533f9e6914386bd03eb4123d8b3 355 Gene3D G3DSA:3.90.25.10 227 332 2.9E-29 T 28-03-2018 hmeg3_RS01980 a832e533f9e6914386bd03eb4123d8b3 355 SUPERFAMILY SSF51735 2 349 1.19E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01980 a832e533f9e6914386bd03eb4123d8b3 355 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 335 3.3E-151 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 hmeg3_RS01980 a832e533f9e6914386bd03eb4123d8b3 355 Gene3D G3DSA:3.40.50.720 1 226 8.3E-57 T 28-03-2018 hmeg3_RS22975 9c37fb7ad65b322383a3b68bebd21ac2 379 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 1 368 48.357 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 hmeg3_RS22975 9c37fb7ad65b322383a3b68bebd21ac2 379 PIRSF PIRSF000443 1 377 3.6E-138 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 hmeg3_RS22975 9c37fb7ad65b322383a3b68bebd21ac2 379 SUPERFAMILY SSF53474 6 365 7.34E-103 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS22975 9c37fb7ad65b322383a3b68bebd21ac2 379 Pfam PF00561 alpha/beta hydrolase fold 44 355 9.1E-33 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS22975 9c37fb7ad65b322383a3b68bebd21ac2 379 Gene3D G3DSA:3.40.50.1820 22 369 9.7E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS22975 9c37fb7ad65b322383a3b68bebd21ac2 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 15 365 1.6E-138 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 hmeg3_RS08050 3457f5f95cbc0d4caefac62ef34f417e 264 SUPERFAMILY SSF52141 16 247 1.55E-23 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS08050 3457f5f95cbc0d4caefac62ef34f417e 264 Gene3D G3DSA:3.40.470.10 3 263 1.7E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 Gene3D G3DSA:1.10.1040.10 180 338 5.2E-58 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 SUPERFAMILY SSF51735 1 182 3.26E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 SUPERFAMILY SSF48179 183 332 9.69E-72 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 3.1E-132 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.766 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 Gene3D G3DSA:3.40.50.720 34 179 2.1E-54 T 28-03-2018 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.7E-71 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 PIRSF PIRSF000116 2 204 2.5E-46 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 PIRSF PIRSF000116 201 333 1.3E-15 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS04910 ce5880b1c8767217e9730a1f5eefc13d 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 3.1E-65 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS20040 ce2a02d0de04c6257f3a7a26be832fd3 168 Gene3D G3DSA:2.30.110.10 1 167 2.2E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS20040 ce2a02d0de04c6257f3a7a26be832fd3 168 SUPERFAMILY SSF50475 13 164 2.89E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS20040 ce2a02d0de04c6257f3a7a26be832fd3 168 SMART SM00903 22 165 9.7E-61 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS20040 ce2a02d0de04c6257f3a7a26be832fd3 168 Pfam PF01613 Flavin reductase like domain 23 164 2.3E-35 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS24195 5ed318138204cd4f81907eb1686ef435 326 Gene3D G3DSA:1.10.3470.10 5 308 9.0E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS24195 5ed318138204cd4f81907eb1686ef435 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 25 279 5.0E-31 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03815 90082aabea890c089c9d4835581b19b3 355 Gene3D G3DSA:3.90.1200.10 125 344 2.0E-15 T 28-03-2018 hmeg3_RS03815 90082aabea890c089c9d4835581b19b3 355 Gene3D G3DSA:3.30.200.20 5 123 7.5E-13 T 28-03-2018 hmeg3_RS03815 90082aabea890c089c9d4835581b19b3 355 Pfam PF01636 Phosphotransferase enzyme family 41 264 7.5E-29 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase hmeg3_RS03815 90082aabea890c089c9d4835581b19b3 355 SUPERFAMILY SSF56112 18 334 1.31E-47 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 50.156 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 Gene3D G3DSA:1.10.645.10 2 233 1.3E-63 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 Gene3D G3DSA:1.10.645.10 234 409 2.5E-45 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 7.5E-188 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 1.5E-124 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13770 7a30acf700bfe406d21fcb989bd8de42 417 SUPERFAMILY SSF56762 16 417 8.37E-138 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS06790 712ddd088228518343421cb6813604d9 196 Gene3D G3DSA:3.40.630.30 14 110 3.3E-16 T 28-03-2018 hmeg3_RS06790 712ddd088228518343421cb6813604d9 196 Pfam PF00583 Acetyltransferase (GNAT) family 74 157 3.3E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS06790 712ddd088228518343421cb6813604d9 196 Gene3D G3DSA:3.40.630.30 111 160 4.6E-11 T 28-03-2018 hmeg3_RS06790 712ddd088228518343421cb6813604d9 196 SUPERFAMILY SSF55729 19 183 8.06E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 SMART SM00862 147 222 9.3E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 Gene3D G3DSA:1.10.10.10 125 225 2.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 Pfam PF00072 Response regulator receiver domain 4 113 5.6E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-32 T 28-03-2018 hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 SMART SM00448 1 113 8.5E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 SUPERFAMILY SSF52172 1 178 8.88E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS02225 20b1be30ca3cd3d5a56844e9ae96ef84 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 1.0E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS00770 7a90203512ec5a35204b202250296763 217 SMART SM00749 138 201 0.05 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS00770 7a90203512ec5a35204b202250296763 217 SMART SM00749 60 123 1.7 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS00770 7a90203512ec5a35204b202250296763 217 Pfam PF04972 BON domain 134 194 1.3E-8 T 28-03-2018 IPR007055 BON domain hmeg3_RS00770 7a90203512ec5a35204b202250296763 217 Pfam PF04972 BON domain 75 123 3.3E-9 T 28-03-2018 IPR007055 BON domain hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 290 7.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 290 306 7.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 Gene3D G3DSA:2.60.120.280 39 192 2.7E-8 T 28-03-2018 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 SUPERFAMILY SSF46689 207 256 1.16E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 SUPERFAMILY SSF46689 260 309 6.72E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 Pfam PF12852 Cupin 2 190 2.6E-32 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 Gene3D G3DSA:1.10.10.60 202 261 9.7E-9 T 28-03-2018 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 260 302 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 SMART SM00342 223 306 2.9E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 Gene3D G3DSA:1.10.10.60 262 318 3.3E-15 T 28-03-2018 hmeg3_RS01045 9f1ea60d973f957634ffa77b39688405 319 Pfam PF12833 Helix-turn-helix domain 229 308 7.2E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 Pfam PF01479 S4 domain 303 346 2.7E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 Gene3D G3DSA:3.30.70.1560 447 509 1.6E-18 T 28-03-2018 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 Gene3D G3DSA:3.10.290.10 300 357 3.8E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 368 528 5.2E-51 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 Pfam PF00849 RNA pseudouridylate synthase 364 497 2.2E-15 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 402 416 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 SUPERFAMILY SSF55120 361 529 1.17E-40 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 SMART SM00363 301 361 1.9E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 Gene3D G3DSA:3.30.70.580 358 446 2.3E-16 T 28-03-2018 hmeg3_RS05575 0cde2c2f4fa49291c263532daa81e801 661 SUPERFAMILY SSF55174 303 394 6.67E-15 T 28-03-2018 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 SMART SM00304 192 245 3.4E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 465 5.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 311 2.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 SUPERFAMILY SSF158472 195 242 8.76E-6 T 28-03-2018 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 5.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 5.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 5.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 SUPERFAMILY SSF55874 302 466 1.57E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 Gene3D G3DSA:1.10.287.130 236 308 6.9E-13 T 28-03-2018 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 SMART SM00388 246 312 2.7E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 8 466 3.9E-133 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 Pfam PF00672 HAMP domain 197 241 1.8E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 SUPERFAMILY SSF47384 229 311 4.51E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 Gene3D G3DSA:3.30.565.10 316 470 2.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15000 7f743d7ef5db9a843035c0604dd3d783 470 SMART SM00387 357 469 1.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 Pfam PF01842 ACT domain 6 68 5.9E-9 T 28-03-2018 IPR002912 ACT domain hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 SUPERFAMILY SSF55021 6 86 2.58E-19 T 28-03-2018 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 SUPERFAMILY SSF53328 90 289 1.11E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 Pfam PF00551 Formyl transferase 90 270 5.2E-33 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 Gene3D G3DSA:3.30.70.260 1 93 2.8E-28 T 28-03-2018 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 Gene3D G3DSA:3.40.50.170 94 289 1.5E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PIRSF PIRSF036480 3 289 7.2E-108 T 28-03-2018 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 6.1E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 6.1E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 90 112 6.1E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 262 287 6.1E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 112 139 6.1E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 240 262 6.1E-52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 288 46.774 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS14910 de8b24878395f960f6723fa105c03311 289 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 7 288 6.6E-101 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 SUPERFAMILY SSF56235 38 226 4.37E-209 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 SUPERFAMILY SSF56235 257 807 4.37E-209 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 Gene3D G3DSA:3.60.20.10 269 364 1.6E-25 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 Gene3D G3DSA:1.10.439.10 30 200 3.5E-45 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 PIRSF PIRSF001227 3 808 8.1E-224 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 Pfam PF01804 Penicillin amidase 43 796 1.9E-210 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 Gene3D G3DSA:1.10.1400.10 561 679 4.9E-23 T 28-03-2018 hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 Gene3D G3DSA:3.60.20.10 680 798 7.6E-17 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS19730 2fcc328a2680bf7567de8382f70ff34a 809 Gene3D G3DSA:3.60.20.10 365 560 2.3E-48 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS17500 1a49032ff2e260b8503fcf3d9cee176a 324 SUPERFAMILY SSF53850 112 286 3.91E-10 T 28-03-2018 hmeg3_RS17500 1a49032ff2e260b8503fcf3d9cee176a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 9.7E-52 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 hmeg3_RS17500 1a49032ff2e260b8503fcf3d9cee176a 324 Gene3D G3DSA:3.40.190.10 124 235 2.0E-13 T 28-03-2018 hmeg3_RS17500 1a49032ff2e260b8503fcf3d9cee176a 324 PIRSF PIRSF017082 1 324 9.1E-81 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 hmeg3_RS06055 20b719f0e3cef64c6b0dd75f00f8e496 192 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 5 188 5.2E-68 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 hmeg3_RS06055 20b719f0e3cef64c6b0dd75f00f8e496 192 Pfam PF02669 K+-transporting ATPase, c chain 6 187 6.9E-74 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 hmeg3_RS06055 20b719f0e3cef64c6b0dd75f00f8e496 192 PIRSF PIRSF001296 1 192 2.2E-74 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 hmeg3_RS06055 20b719f0e3cef64c6b0dd75f00f8e496 192 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 189 34.476 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 hmeg3_RS19065 e5245cbc40c4d94f27f530ed197b8d39 431 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 113 409 1.3E-47 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS19065 e5245cbc40c4d94f27f530ed197b8d39 431 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 115 346 2.2E-42 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS19065 e5245cbc40c4d94f27f530ed197b8d39 431 SUPERFAMILY SSF111369 128 350 1.44E-25 T 28-03-2018 hmeg3_RS19065 e5245cbc40c4d94f27f530ed197b8d39 431 Gene3D G3DSA:1.20.1600.10 143 375 1.4E-22 T 28-03-2018 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 Gene3D G3DSA:1.10.357.10 74 204 9.2E-11 T 28-03-2018 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 Gene3D G3DSA:1.10.10.60 2 42 1.9E-14 T 28-03-2018 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 Gene3D G3DSA:1.10.260.40 43 73 2.5E-12 T 28-03-2018 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 8.2E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS12835 4086f5dd24e637d2cce14035756366c2 208 SUPERFAMILY SSF46689 8 83 8.98E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Pfam PF02875 Mur ligase family, glutamate ligase domain 343 429 2.8E-21 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 SUPERFAMILY SSF53623 99 340 1.26E-62 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Gene3D G3DSA:3.90.190.20 350 504 6.5E-45 T 28-03-2018 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Pfam PF08245 Mur ligase middle domain 108 322 7.0E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Gene3D G3DSA:3.40.1390.10 2 98 4.1E-19 T 28-03-2018 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 SUPERFAMILY SSF53244 343 496 1.83E-42 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Pfam PF01225 Mur ligase family, catalytic domain 22 85 7.6E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Gene3D G3DSA:3.40.1190.10 99 347 1.5E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 496 1.6E-133 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 SUPERFAMILY SSF63418 17 97 2.22E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 hmeg3_RS22035 1c7ab47e29f664d6cca7e37469539b5f 506 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 3 496 31.145 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 hmeg3_RS05910 1e3ba33670bb45630a079f3031f1b1eb 177 Pfam PF04773 FecR protein 86 173 1.1E-11 T 28-03-2018 IPR006860 FecR protein hmeg3_RS04105 2895581ad25a784dee662f0f8476ee26 101 Pfam PF12840 Helix-turn-helix domain 12 68 4.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04105 2895581ad25a784dee662f0f8476ee26 101 SMART SM00418 8 89 1.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS04105 2895581ad25a784dee662f0f8476ee26 101 Gene3D G3DSA:1.10.10.10 1 86 6.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04105 2895581ad25a784dee662f0f8476ee26 101 SUPERFAMILY SSF46785 7 90 1.19E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08240 d24f80354b2b65d7e1f6c89fdb6ad169 377 Gene3D G3DSA:1.20.1330.10 225 371 0.071 T 28-03-2018 hmeg3_RS08240 d24f80354b2b65d7e1f6c89fdb6ad169 377 Gene3D G3DSA:1.20.1330.10 38 221 5.1E-17 T 28-03-2018 hmeg3_RS08240 d24f80354b2b65d7e1f6c89fdb6ad169 377 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 376 1.0E-70 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 hmeg3_RS08240 d24f80354b2b65d7e1f6c89fdb6ad169 377 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 1.0E-13 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 hmeg3_RS08240 d24f80354b2b65d7e1f6c89fdb6ad169 377 SUPERFAMILY SSF64518 1 377 3.92E-48 T 28-03-2018 hmeg3_RS23085 9af4158f8c9c072431959a65a722e27c 232 Pfam PF02390 Putative methyltransferase 54 218 1.7E-12 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 hmeg3_RS23085 9af4158f8c9c072431959a65a722e27c 232 SUPERFAMILY SSF53335 45 219 2.97E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS23085 9af4158f8c9c072431959a65a722e27c 232 Gene3D G3DSA:3.40.50.150 21 223 1.8E-11 T 28-03-2018 hmeg3_RS11215 4950d54829f4151333948b540da0db7a 277 Gene3D G3DSA:3.40.50.300 3 252 5.4E-63 T 28-03-2018 hmeg3_RS11215 4950d54829f4151333948b540da0db7a 277 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11215 4950d54829f4151333948b540da0db7a 277 SUPERFAMILY SSF52540 7 240 1.46E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11215 4950d54829f4151333948b540da0db7a 277 SMART SM00382 35 232 3.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11215 4950d54829f4151333948b540da0db7a 277 Pfam PF00005 ABC transporter 26 165 3.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10690 511f81fa2b7127b2026116d7e4d87090 477 Gene3D G3DSA:3.40.309.10 262 458 1.2E-60 T 28-03-2018 hmeg3_RS10690 511f81fa2b7127b2026116d7e4d87090 477 Gene3D G3DSA:3.40.605.10 1 261 4.2E-99 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS10690 511f81fa2b7127b2026116d7e4d87090 477 SUPERFAMILY SSF53720 3 475 3.01E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS10690 511f81fa2b7127b2026116d7e4d87090 477 Pfam PF00171 Aldehyde dehydrogenase family 10 472 7.0E-158 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS10690 511f81fa2b7127b2026116d7e4d87090 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS10690 511f81fa2b7127b2026116d7e4d87090 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 21 243 4.0E-75 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 12 243 36.162 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 Gene3D G3DSA:3.40.50.150 16 241 4.4E-44 T 28-03-2018 hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 Pfam PF01209 ubiE/COQ5 methyltransferase family 17 243 1.7E-86 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 SUPERFAMILY SSF53335 1 235 9.91E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 152 166 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 hmeg3_RS04395 8bfa6b7ec00bf50f821213c054da3231 244 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 32 47 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 hmeg3_RS08340 6fe328eea6a9fd857837d58759bf6fb0 391 Pfam PF02120 Flagellar hook-length control protein FliK 317 389 2.4E-12 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal hmeg3_RS21935 e051cd94939c2c22380983eeffc5ee7c 143 Gene3D G3DSA:3.90.79.10 12 137 5.3E-29 T 28-03-2018 hmeg3_RS21935 e051cd94939c2c22380983eeffc5ee7c 143 Pfam PF00293 NUDIX domain 19 125 1.4E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS21935 e051cd94939c2c22380983eeffc5ee7c 143 PRINTS PR00502 NUDIX hydrolase family signature 45 59 1.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 hmeg3_RS21935 e051cd94939c2c22380983eeffc5ee7c 143 PRINTS PR00502 NUDIX hydrolase family signature 59 74 1.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 hmeg3_RS21935 e051cd94939c2c22380983eeffc5ee7c 143 SUPERFAMILY SSF55811 15 129 7.72E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS21935 e051cd94939c2c22380983eeffc5ee7c 143 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 Gene3D G3DSA:2.40.170.20 179 754 3.7E-74 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 SUPERFAMILY SSF56935 38 755 1.28E-112 T 28-03-2018 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 Gene3D G3DSA:2.170.130.10 35 178 1.7E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 181 1.8E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 43 755 7.4E-108 T 28-03-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 Pfam PF00593 TonB dependent receptor 307 753 7.9E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22895 f995a6f1376a3656246ec2e30e70a924 755 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 45 755 6.9E-114 T 28-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 hmeg3_RS14210 c7f618e109cf965ba7c4f9cd0f873c16 411 Gene3D G3DSA:1.20.1250.20 15 210 8.3E-23 T 28-03-2018 hmeg3_RS14210 c7f618e109cf965ba7c4f9cd0f873c16 411 Pfam PF07690 Major Facilitator Superfamily 31 368 2.5E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS14210 c7f618e109cf965ba7c4f9cd0f873c16 411 SUPERFAMILY SSF103473 1 406 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS14210 c7f618e109cf965ba7c4f9cd0f873c16 411 Gene3D G3DSA:1.20.1250.20 211 406 3.0E-23 T 28-03-2018 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 SUPERFAMILY SSF82679 21 132 1.44E-39 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 SMART SM00738 21 130 6.9E-48 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 PRINTS PR00338 Transcription termination factor NUSG signature 172 188 2.1E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 PRINTS PR00338 Transcription termination factor NUSG signature 154 169 2.1E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 PRINTS PR00338 Transcription termination factor NUSG signature 76 88 2.1E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 21 196 25.248 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 Gene3D G3DSA:2.30.30.30 137 196 2.1E-20 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 SMART SM00739 142 169 1.4E-4 T 28-03-2018 IPR005824 KOW hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 Gene3D G3DSA:3.30.70.940 21 134 1.2E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 ProSitePatterns PS01014 Transcription termination factor nusG signature. 179 188 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 SUPERFAMILY SSF50104 140 196 1.2E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 24 196 3.3E-67 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 Pfam PF00467 KOW motif 145 177 1.5E-6 T 28-03-2018 IPR005824 KOW hmeg3_RS22930 924b94bbfc92f8bd78b86deb2a4fb177 196 Pfam PF02357 Transcription termination factor nusG 22 127 2.9E-26 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 SUPERFAMILY SSF53850 92 298 5.67E-36 T 28-03-2018 hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 Gene3D G3DSA:3.40.190.10 180 271 3.7E-17 T 28-03-2018 hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 Gene3D G3DSA:1.10.10.10 1 90 4.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 SUPERFAMILY SSF46785 4 115 9.24E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 Pfam PF03466 LysR substrate binding domain 92 294 4.5E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS08620 4e307e8c5128b5542912d449558bb88f 303 Gene3D G3DSA:3.40.190.10 92 179 8.8E-19 T 28-03-2018 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 SUPERFAMILY SSF46785 14 84 2.41E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 Gene3D G3DSA:3.90.1150.10 388 486 2.0E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 Gene3D G3DSA:3.40.640.10 144 387 3.9E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 1.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 1.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 SUPERFAMILY SSF53383 121 485 9.37E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 Gene3D G3DSA:1.10.10.10 12 85 9.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 Pfam PF00155 Aminotransferase class I and II 153 445 1.8E-25 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 1.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05285 e39d25403996160140a056acc8d8ec22 486 SMART SM00345 24 83 1.5E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 Gene3D G3DSA:3.50.50.60 5 265 4.2E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 628 2.0E-272 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 SUPERFAMILY SSF51905 6 66 8.96E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 SUPERFAMILY SSF51905 97 262 8.96E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 631 42.286 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 SMART SM01228 553 624 1.3E-44 T 28-03-2018 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 Pfam PF13932 GidA associated domain 403 623 2.9E-78 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 hmeg3_RS24180 cf6c9e861326061a8c34a97c2d31c647 651 Pfam PF01134 Glucose inhibited division protein A 8 399 1.2E-163 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Gene3D G3DSA:3.90.190.20 326 470 6.4E-27 T 28-03-2018 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Pfam PF08245 Mur ligase middle domain 108 304 9.9E-23 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 SUPERFAMILY SSF53244 324 469 7.46E-36 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Gene3D G3DSA:3.40.50.720 1 90 8.8E-13 T 28-03-2018 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 469 7.8E-212 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Gene3D G3DSA:3.40.1190.10 91 325 2.9E-47 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 470 58.035 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 SUPERFAMILY SSF51984 1 90 4.71E-22 T 28-03-2018 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 376 6.6E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 Pfam PF01225 Mur ligase family, catalytic domain 2 100 1.1E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 hmeg3_RS21735 e9fedc50a4dde8606abc4405eecaee56 470 SUPERFAMILY SSF53623 97 321 1.07E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 Pfam PF00005 ABC transporter 44 193 2.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 329 4.8E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 Gene3D G3DSA:3.40.50.300 11 343 1.8E-82 T 28-03-2018 hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 SUPERFAMILY SSF52540 14 265 1.98E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 SMART SM00382 52 243 3.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00445 b0b745d2b785cb689301326505daf340 348 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 310 9.5E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 SUPERFAMILY SSF53850 92 295 3.09E-32 T 28-03-2018 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 Pfam PF03466 LysR substrate binding domain 90 294 1.2E-30 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 Gene3D G3DSA:1.10.10.10 1 85 1.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 Gene3D G3DSA:3.40.190.10 180 266 2.2E-15 T 28-03-2018 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 SUPERFAMILY SSF46785 2 112 5.93E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 Gene3D G3DSA:3.40.190.10 89 179 2.2E-16 T 28-03-2018 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23600 8397ed2cc60d3328dba5f135a92ce176 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11400 c1ff41ad702177eeded647722df735e1 465 Gene3D G3DSA:3.20.20.70 146 452 1.3E-165 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS11400 c1ff41ad702177eeded647722df735e1 465 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 15 446 5.0E-224 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 hmeg3_RS11400 c1ff41ad702177eeded647722df735e1 465 PIRSF PIRSF018788 4 461 2.4E-239 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 hmeg3_RS11400 c1ff41ad702177eeded647722df735e1 465 Gene3D G3DSA:2.30.170.30 5 56 1.2E-23 T 28-03-2018 hmeg3_RS11400 c1ff41ad702177eeded647722df735e1 465 Gene3D G3DSA:1.10.220.70 59 143 1.1E-38 T 28-03-2018 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.1E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.1E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 3.1E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 3.1E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 3.1E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 SUPERFAMILY SSF54919 1 139 1.44E-56 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 Gene3D G3DSA:3.30.70.141 1 54 3.2E-17 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 Gene3D G3DSA:3.30.70.141 55 140 3.0E-31 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 SMART SM00562 3 140 7.3E-81 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 Pfam PF00334 Nucleoside diphosphate kinase 4 136 1.6E-54 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS08850 d3b57ecdc385d70acbc8665f577ddf87 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.708 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 Pfam PF00361 Proton-conducting membrane transporter 136 418 6.0E-77 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 489 4.6E-186 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 3.9E-49 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 3.9E-49 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 3.9E-49 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 240 264 3.9E-49 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 170 194 3.9E-49 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13725 e7e91dacb18135e24a3eb23fd6c9383a 496 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 75 127 3.7E-5 T 28-03-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 Gene3D G3DSA:3.40.190.10 179 265 8.6E-20 T 28-03-2018 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 Pfam PF03466 LysR substrate binding domain 93 294 2.4E-44 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 SUPERFAMILY SSF46785 5 115 9.54E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 3.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 Gene3D G3DSA:1.10.10.10 1 87 5.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 8.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 8.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 8.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 Gene3D G3DSA:3.40.190.10 93 178 7.8E-25 T 28-03-2018 hmeg3_RS10270 d42cfe92eab1a8b17c99d494366afa86 301 SUPERFAMILY SSF53850 94 296 4.28E-45 T 28-03-2018 hmeg3_RS07110 37e2a2ebf9ce89f44a74e6938c20a11d 740 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 159 8.9E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07110 37e2a2ebf9ce89f44a74e6938c20a11d 740 Gene3D G3DSA:2.40.170.20 172 739 1.8E-73 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07110 37e2a2ebf9ce89f44a74e6938c20a11d 740 SUPERFAMILY SSF56935 31 739 1.44E-118 T 28-03-2018 hmeg3_RS07110 37e2a2ebf9ce89f44a74e6938c20a11d 740 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 63 738 1.8E-76 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS07110 37e2a2ebf9ce89f44a74e6938c20a11d 740 Pfam PF00593 TonB dependent receptor 245 739 3.1E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07110 37e2a2ebf9ce89f44a74e6938c20a11d 740 Gene3D G3DSA:2.170.130.10 27 166 2.1E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 Gene3D G3DSA:3.40.50.2300 4 170 4.3E-30 T 28-03-2018 hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 SUPERFAMILY SSF53822 13 363 6.28E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 Gene3D G3DSA:3.40.50.2300 171 344 1.5E-18 T 28-03-2018 hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 Pfam PF13458 Periplasmic binding protein 13 352 4.8E-65 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 34 50 1.6E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 71 1.6E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14585 08ee51dca490e41ee4a2c0be6e604a91 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 321 336 1.6E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS03075 0f51f9a0cb2e2541a891b7c6856fc3d2 242 SUPERFAMILY SSF52540 3 237 3.79E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03075 0f51f9a0cb2e2541a891b7c6856fc3d2 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03075 0f51f9a0cb2e2541a891b7c6856fc3d2 242 Pfam PF00005 ABC transporter 19 167 6.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03075 0f51f9a0cb2e2541a891b7c6856fc3d2 242 PIRSF PIRSF039085 1 242 6.1E-108 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS03075 0f51f9a0cb2e2541a891b7c6856fc3d2 242 Gene3D G3DSA:3.40.50.300 1 242 1.9E-72 T 28-03-2018 hmeg3_RS03075 0f51f9a0cb2e2541a891b7c6856fc3d2 242 SMART SM00382 28 215 1.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Gene3D G3DSA:3.30.450.20 37 165 1.5E-6 T 28-03-2018 hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Pfam PF00563 EAL domain 645 880 7.4E-71 T 28-03-2018 IPR001633 EAL domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Gene3D G3DSA:3.30.450.20 303 447 5.6E-8 T 28-03-2018 hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Gene3D G3DSA:3.30.70.270 448 631 1.9E-50 T 28-03-2018 hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Gene3D G3DSA:3.20.20.450 632 888 3.9E-94 T 28-03-2018 IPR001633 EAL domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 SUPERFAMILY SSF55073 454 631 1.18E-39 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 542 627 1.1E-12 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 448 518 6.4E-19 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Pfam PF00990 Diguanylate cyclase, GGDEF domain 542 625 4.8E-15 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Pfam PF00990 Diguanylate cyclase, GGDEF domain 450 521 2.0E-19 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 SMART SM00267 438 629 1.3E-40 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 SUPERFAMILY SSF141868 644 896 1.44E-84 T 28-03-2018 IPR001633 EAL domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 Gene3D G3DSA:3.30.450.20 166 283 1.0E-7 T 28-03-2018 hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 SUPERFAMILY SSF55785 349 445 6.28E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS14965 bb05b47ea4015ca31437f88fb14b1030 904 SMART SM00052 639 885 3.7E-99 T 28-03-2018 IPR001633 EAL domain hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 35 131 30.989 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 PRINTS PR01727 Prokaryotic integration host factor signature 94 107 2.7E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 PRINTS PR01727 Prokaryotic integration host factor signature 110 124 2.7E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 PRINTS PR01727 Prokaryotic integration host factor signature 76 91 2.7E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 SMART SM00411 37 126 3.7E-40 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 Pfam PF00216 Bacterial DNA-binding protein 37 125 1.7E-30 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 SUPERFAMILY SSF47729 37 127 5.15E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 82 101 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 36 128 2.9E-46 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 hmeg3_RS07780 903eb2adc0ceaaa091323f82710e2a79 137 Gene3D G3DSA:4.10.520.10 35 132 2.1E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 Gene3D G3DSA:1.10.287.950 320 517 1.8E-48 T 28-03-2018 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 Gene3D G3DSA:1.10.287.950 106 319 1.0E-14 T 28-03-2018 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 Pfam PF05227 CHASE3 domain 40 180 1.7E-35 T 28-03-2018 IPR007891 CHASE3 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 SUPERFAMILY SSF58104 233 514 1.96E-73 T 28-03-2018 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.4E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 SMART SM00304 213 265 1.7E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 SMART SM00283 266 513 4.4E-89 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 Pfam PF00672 HAMP domain 214 260 4.0E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 190 210 1.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 1.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15250 3e505b610e1450fd1295e751f40112ff 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 Gene3D G3DSA:1.10.287.950 33 369 3.1E-17 T 28-03-2018 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 Gene3D G3DSA:1.10.287.950 370 549 2.2E-44 T 28-03-2018 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 403 430 2.9E-26 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 326 355 2.9E-26 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 432 461 2.9E-26 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 SUPERFAMILY SSF58104 280 546 1.22E-61 T 28-03-2018 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 SMART SM00283 312 545 5.3E-69 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20335 8131a8c799b6118d1594d1cd50a1e8f4 599 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 372 531 2.7E-34 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS18105 887f555c227b37bb437f77503347e177 306 Pfam PF13103 TonB C terminal 217 300 1.7E-16 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 hmeg3_RS18105 887f555c227b37bb437f77503347e177 306 TIGRFAM TIGR02794 tolA_full: protein TolA 103 297 1.5E-23 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 hmeg3_RS18105 887f555c227b37bb437f77503347e177 306 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 245 298 5.9E-8 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 hmeg3_RS18105 887f555c227b37bb437f77503347e177 306 SUPERFAMILY SSF74653 217 295 1.57E-12 T 28-03-2018 hmeg3_RS18105 887f555c227b37bb437f77503347e177 306 Gene3D G3DSA:2.130.10.10 10 208 2.5E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS18105 887f555c227b37bb437f77503347e177 306 Gene3D G3DSA:3.30.1150.10 224 299 1.4E-13 T 28-03-2018 hmeg3_RS01995 8d9f81b5e58cbe2c3bb2fc7355c6b54e 325 Gene3D G3DSA:3.40.50.620 32 265 9.8E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS01995 8d9f81b5e58cbe2c3bb2fc7355c6b54e 325 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 32 295 56.695 T 28-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 hmeg3_RS01995 8d9f81b5e58cbe2c3bb2fc7355c6b54e 325 Pfam PF01171 PP-loop family 65 230 1.0E-17 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 hmeg3_RS01995 8d9f81b5e58cbe2c3bb2fc7355c6b54e 325 PIRSF PIRSF004976 21 298 4.5E-69 T 28-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 hmeg3_RS01995 8d9f81b5e58cbe2c3bb2fc7355c6b54e 325 SUPERFAMILY SSF52402 52 282 7.24E-55 T 28-03-2018 hmeg3_RS21345 9b8980f0b5ba966f2e1ee45ba8f5575f 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 241 8.4E-80 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS21345 9b8980f0b5ba966f2e1ee45ba8f5575f 313 SUPERFAMILY SSF51735 7 309 1.37E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21345 9b8980f0b5ba966f2e1ee45ba8f5575f 313 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 7 309 47.667 T 28-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 hmeg3_RS21345 9b8980f0b5ba966f2e1ee45ba8f5575f 313 Gene3D G3DSA:3.40.50.720 3 169 3.3E-9 T 28-03-2018 hmeg3_RS21345 9b8980f0b5ba966f2e1ee45ba8f5575f 313 Gene3D G3DSA:3.90.25.10 170 312 4.4E-43 T 28-03-2018 hmeg3_RS07860 b497fb07af2e85bf689e1c0af7222915 460 Pfam PF02706 Chain length determinant protein 14 97 1.3E-6 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 hmeg3_RS07860 b497fb07af2e85bf689e1c0af7222915 460 Gene3D G3DSA:3.30.1890.10 41 408 1.5E-17 T 28-03-2018 hmeg3_RS04885 afbcfb8a4d6893d74683331824992652 628 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 219 623 3.3E-85 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS04885 afbcfb8a4d6893d74683331824992652 628 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 44 169 7.4E-29 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component hmeg3_RS04885 afbcfb8a4d6893d74683331824992652 628 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 211 621 7.6E-93 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit hmeg3_RS07225 391b62e4322671597f13dbf68de6f921 203 Pfam PF04751 Protein of unknown function (DUF615) 22 175 6.3E-54 T 28-03-2018 IPR006839 Ribosome-associated, YjgA hmeg3_RS07225 391b62e4322671597f13dbf68de6f921 203 PIRSF PIRSF016183 10 183 2.3E-63 T 28-03-2018 IPR006839 Ribosome-associated, YjgA hmeg3_RS07225 391b62e4322671597f13dbf68de6f921 203 SUPERFAMILY SSF158710 32 177 3.27E-48 T 28-03-2018 IPR023153 PSPTO4464-like domain hmeg3_RS07225 391b62e4322671597f13dbf68de6f921 203 Gene3D G3DSA:1.10.60.30 111 185 1.5E-26 T 28-03-2018 hmeg3_RS07225 391b62e4322671597f13dbf68de6f921 203 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 12 179 21.741 T 28-03-2018 IPR006839 Ribosome-associated, YjgA hmeg3_RS07225 391b62e4322671597f13dbf68de6f921 203 Gene3D G3DSA:1.10.60.30 34 105 1.8E-27 T 28-03-2018 hmeg3_RS08555 f5d9fad6d4938aa6de566a497025ef07 247 Gene3D G3DSA:3.40.50.720 4 238 1.5E-20 T 28-03-2018 hmeg3_RS08555 f5d9fad6d4938aa6de566a497025ef07 247 SUPERFAMILY SSF51735 2 242 8.48E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08555 f5d9fad6d4938aa6de566a497025ef07 247 Pfam PF13460 NAD(P)H-binding 9 180 1.4E-9 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21265 a7b060446cd965479775d8f42db98bff 363 Pfam PF16363 GDP-mannose 4,6 dehydratase 19 326 2.6E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21265 a7b060446cd965479775d8f42db98bff 363 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 12 350 4.0E-148 T 28-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 hmeg3_RS21265 a7b060446cd965479775d8f42db98bff 363 SUPERFAMILY SSF51735 15 335 8.28E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21265 a7b060446cd965479775d8f42db98bff 363 Gene3D G3DSA:3.40.50.720 9 201 1.5E-30 T 28-03-2018 hmeg3_RS21265 a7b060446cd965479775d8f42db98bff 363 Gene3D G3DSA:3.90.25.10 202 354 2.5E-24 T 28-03-2018 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 SUPERFAMILY SSF54631 93 201 4.88E-25 T 28-03-2018 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 SMART SM01240 6 472 0.0 T 28-03-2018 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 SMART SM00116 95 142 1.8E-7 T 28-03-2018 IPR000644 CBS domain hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 SMART SM00116 156 204 1.1E-6 T 28-03-2018 IPR000644 CBS domain hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 Pfam PF00571 CBS domain 94 138 8.6E-8 T 28-03-2018 IPR000644 CBS domain hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 Pfam PF00571 CBS domain 153 199 5.4E-6 T 28-03-2018 IPR000644 CBS domain hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 PIRSF PIRSF000130 1 486 3.5E-207 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 Gene3D G3DSA:3.20.20.70 2 179 1.2E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 Gene3D G3DSA:3.20.20.70 180 482 1.1E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 454 2.4E-190 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 84.292 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 1.4E-165 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 SUPERFAMILY SSF51412 215 476 1.09E-127 T 28-03-2018 hmeg3_RS10075 c37edc95d558c3dcdee9aed39ea9a806 486 SUPERFAMILY SSF51412 2 89 1.09E-127 T 28-03-2018 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 SMART SM00841 128 188 3.7E-14 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Pfam PF09285 Elongation factor P, C-terminal 128 186 1.3E-19 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 SMART SM01185 67 120 3.7E-20 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Hamap MF_00141 Elongation factor P [efp]. 1 189 38.676 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Gene3D G3DSA:2.40.50.140 128 187 3.5E-19 T 28-03-2018 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Gene3D G3DSA:2.40.50.140 65 125 2.7E-21 T 28-03-2018 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 4.0E-11 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 SUPERFAMILY SSF50249 128 187 1.54E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 PIRSF PIRSF005901 1 190 6.2E-47 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 SUPERFAMILY SSF50104 1 63 6.02E-12 T 28-03-2018 IPR008991 Translation protein SH3-like domain hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Gene3D G3DSA:2.30.30.30 2 61 4.6E-12 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 1.1E-17 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 hmeg3_RS15090 62b2fe77ea6c76065290749967decd80 191 SUPERFAMILY SSF50249 65 126 1.2E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS06905 94f270eac91021324f76073ceabc47c7 250 Pfam PF01925 Sulfite exporter TauE/SafE 12 243 1.5E-22 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 SUPERFAMILY SSF53067 5 171 1.45E-29 T 28-03-2018 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 SUPERFAMILY SSF53067 291 411 2.36E-31 T 28-03-2018 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 SUPERFAMILY SSF53067 174 242 2.36E-31 T 28-03-2018 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 Gene3D G3DSA:3.30.420.40 1 183 1.1E-36 T 28-03-2018 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.8E-5 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.8E-5 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 PRINTS PR00301 70kDa heat shock protein signature 119 139 1.8E-5 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 PRINTS PR00301 70kDa heat shock protein signature 185 195 1.8E-5 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 Pfam PF00012 Hsp70 protein 95 225 7.8E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 Pfam PF00012 Hsp70 protein 293 388 6.0E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 Pfam PF00012 Hsp70 protein 5 85 3.2E-6 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS22250 09efe16303fad6d0b9aaea5c506c6b85 416 Gene3D G3DSA:3.30.420.40 184 393 1.2E-29 T 28-03-2018 hmeg3_RS06310 b0871b6641d6aa2be8760aad384fe943 139 Gene3D G3DSA:2.20.25.10 1 45 3.9E-19 T 28-03-2018 hmeg3_RS06310 b0871b6641d6aa2be8760aad384fe943 139 SUPERFAMILY SSF82784 6 138 1.83E-39 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS06310 b0871b6641d6aa2be8760aad384fe943 139 Pfam PF02566 OsmC-like protein 41 136 4.7E-17 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS06310 b0871b6641d6aa2be8760aad384fe943 139 Gene3D G3DSA:3.30.300.20 46 139 1.3E-21 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS06310 b0871b6641d6aa2be8760aad384fe943 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 8 137 7.7E-47 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 Gene3D G3DSA:3.30.1440.10 1 179 2.5E-74 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.156 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 SUPERFAMILY SSF55282 3 179 8.71E-75 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 PIRSF PIRSF002161 1 179 1.4E-62 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.6E-39 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22800 ceae9b0e60de99b390996f337ee80fa3 179 Pfam PF00281 Ribosomal protein L5 24 80 2.5E-25 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 Gene3D G3DSA:3.40.50.980 216 374 2.8E-41 T 28-03-2018 hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 547 1.3E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 Gene3D G3DSA:3.40.50.980 20 215 4.2E-41 T 28-03-2018 hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 Pfam PF00501 AMP-binding enzyme 32 464 3.4E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 Gene3D G3DSA:3.30.300.30 458 563 6.3E-28 T 28-03-2018 hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 SUPERFAMILY SSF56801 17 559 4.97E-152 T 28-03-2018 hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS04630 0a6e882a34cc7c7cc1c577cdcbbbabaf 564 Gene3D G3DSA:2.30.38.10 375 457 7.9E-28 T 28-03-2018 hmeg3_RS20190 f2dbff70b47eee8a6be75fc1aa8cec96 140 Pfam PF02566 OsmC-like protein 41 136 2.8E-21 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS20190 f2dbff70b47eee8a6be75fc1aa8cec96 140 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 2 136 4.2E-55 T 28-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 hmeg3_RS20190 f2dbff70b47eee8a6be75fc1aa8cec96 140 SUPERFAMILY SSF82784 2 138 8.9E-38 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS20190 f2dbff70b47eee8a6be75fc1aa8cec96 140 Gene3D G3DSA:3.30.300.20 1 140 2.5E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 15 231 9.6E-65 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 252 18.293 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 Pfam PF00902 Sec-independent protein translocase protein (TatC) 17 226 1.2E-63 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 90 108 2.2E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 159 187 2.2E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 108 134 2.2E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS03540 21ec865f762a59f2da48d2ac40c362a5 257 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 13 40 2.2E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 hmeg3_RS08185 f63ac5f67b84f0eea954928a19331ea3 240 Pfam PF13144 Chaperone for flagella basal body P-ring formation 40 238 7.3E-52 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal hmeg3_RS08185 f63ac5f67b84f0eea954928a19331ea3 240 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 104 239 1.4E-38 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal hmeg3_RS08185 f63ac5f67b84f0eea954928a19331ea3 240 Gene3D G3DSA:3.90.1210.10 115 188 5.1E-11 T 28-03-2018 hmeg3_RS08185 f63ac5f67b84f0eea954928a19331ea3 240 SMART SM00858 116 178 5.0E-11 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 SMART SM00283 394 641 1.7E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 SUPERFAMILY SSF58104 361 642 9.81E-76 T 28-03-2018 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 8.1E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 521 550 8.1E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 492 519 8.1E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 569 598 8.1E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 Pfam PF08376 Nitrate and nitrite sensing 60 297 2.5E-12 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 455 609 2.2E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 Gene3D G3DSA:1.10.287.950 82 448 2.0E-17 T 28-03-2018 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 Gene3D G3DSA:1.10.287.950 449 645 4.5E-48 T 28-03-2018 hmeg3_RS06150 c61dbde0a8a4ffef0019922d9d90bbdb 720 SMART SM00304 341 393 1.3E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS20530 d3564d65c4885bdb467898a96b25a113 175 Pfam PF12973 ChrR Cupin-like domain 39 126 3.6E-16 T 28-03-2018 IPR025979 ChrR-like cupin domain hmeg3_RS20530 d3564d65c4885bdb467898a96b25a113 175 Gene3D G3DSA:2.60.120.10 24 175 3.6E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS20530 d3564d65c4885bdb467898a96b25a113 175 SUPERFAMILY SSF51182 32 156 7.29E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS13865 5c3f56b8d6f1adc0ccd77773dc1f27cd 165 Gene3D G3DSA:3.30.1450.10 20 79 0.072 T 28-03-2018 hmeg3_RS13865 5c3f56b8d6f1adc0ccd77773dc1f27cd 165 Gene3D G3DSA:3.30.1450.10 80 153 1.8E-8 T 28-03-2018 hmeg3_RS13865 5c3f56b8d6f1adc0ccd77773dc1f27cd 165 Pfam PF04355 SmpA / OmlA family 85 150 4.0E-5 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 SUPERFAMILY SSF53850 88 294 1.48E-22 T 28-03-2018 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 SUPERFAMILY SSF46785 4 86 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 Pfam PF03466 LysR substrate binding domain 88 285 1.2E-21 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 Gene3D G3DSA:3.40.190.10 180 266 2.6E-8 T 28-03-2018 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 Gene3D G3DSA:1.10.10.10 3 88 3.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 Gene3D G3DSA:3.40.190.10 89 179 1.9E-9 T 28-03-2018 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS03970 70e98951a24a3b77808c253a176bf9b7 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.6E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 SUPERFAMILY SSF160240 220 297 1.57E-22 T 28-03-2018 hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 Gene3D G3DSA:3.30.70.1350 215 297 3.1E-22 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 SUPERFAMILY SSF161111 16 217 5.49E-54 T 28-03-2018 hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 Pfam PF01545 Cation efflux family 24 216 8.6E-44 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 20 296 4.7E-65 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 221 296 3.1E-23 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain hmeg3_RS20610 e5b412f5ed14812730c4b7be2bb43f9a 297 Gene3D G3DSA:1.20.1510.10 19 214 3.5E-43 T 28-03-2018 hmeg3_RS20895 70f9c16fd9e8967bff7404c85818cb5e 317 SUPERFAMILY SSF51197 8 281 1.92E-77 T 28-03-2018 hmeg3_RS20895 70f9c16fd9e8967bff7404c85818cb5e 317 Gene3D G3DSA:3.60.130.10 2 284 1.5E-62 T 28-03-2018 hmeg3_RS20895 70f9c16fd9e8967bff7404c85818cb5e 317 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 277 8.1E-61 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS01970 75fef7f266cef0832eeb368317b420ab 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 3.0E-73 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 hmeg3_RS01970 75fef7f266cef0832eeb368317b420ab 181 SUPERFAMILY SSF51182 1 178 5.56E-77 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS01970 75fef7f266cef0832eeb368317b420ab 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 1.9E-82 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 hmeg3_RS01970 75fef7f266cef0832eeb368317b420ab 181 Gene3D G3DSA:2.60.120.10 1 180 2.6E-74 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS01970 75fef7f266cef0832eeb368317b420ab 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 1.2E-74 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 SMART SM00100 30 151 1.8E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 SMART SM00419 187 235 8.1E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 SUPERFAMILY SSF46785 166 245 1.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 SUPERFAMILY SSF51206 23 162 1.96E-28 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 Pfam PF13545 Crp-like helix-turn-helix domain 168 242 1.5E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 Gene3D G3DSA:1.10.10.10 165 251 3.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 Pfam PF00027 Cyclic nucleotide-binding domain 49 133 1.6E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 Gene3D G3DSA:2.60.120.10 26 164 2.0E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 209 224 2.9E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 209 2.9E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 hmeg3_RS12185 b91dded9005cb257063adf140b68ef88 252 ProSitePatterns PS00042 Crp-type HTH domain signature. 195 218 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 hmeg3_RS02325 8b745e52bd7b0ff71e25f1f1a9c02f51 343 SUPERFAMILY SSF53850 28 337 7.65E-97 T 28-03-2018 hmeg3_RS02325 8b745e52bd7b0ff71e25f1f1a9c02f51 343 Gene3D G3DSA:3.40.190.10 158 340 1.7E-23 T 28-03-2018 hmeg3_RS02325 8b745e52bd7b0ff71e25f1f1a9c02f51 343 Gene3D G3DSA:3.40.190.10 26 157 5.4E-32 T 28-03-2018 hmeg3_RS02325 8b745e52bd7b0ff71e25f1f1a9c02f51 343 PIRSF PIRSF002756 4 339 2.4E-106 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 hmeg3_RS02325 8b745e52bd7b0ff71e25f1f1a9c02f51 343 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 337 3.8E-124 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 hmeg3_RS02325 8b745e52bd7b0ff71e25f1f1a9c02f51 343 Pfam PF12849 PBP superfamily domain 25 308 4.8E-58 T 28-03-2018 IPR024370 PBP domain hmeg3_RS21550 04de3817d7c50c022fcf13a9e7f16038 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 9.7E-17 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis hmeg3_RS21550 04de3817d7c50c022fcf13a9e7f16038 66 Pfam PF02597 ThiS family 4 66 2.2E-11 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 hmeg3_RS21550 04de3817d7c50c022fcf13a9e7f16038 66 SUPERFAMILY SSF54285 2 65 2.45E-14 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp hmeg3_RS21550 04de3817d7c50c022fcf13a9e7f16038 66 Gene3D G3DSA:3.10.20.30 1 66 6.1E-19 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 Gene3D G3DSA:3.40.50.20 1 128 7.1E-48 T 28-03-2018 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 311 7.2E-128 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 SUPERFAMILY SSF56059 122 309 8.52E-57 T 28-03-2018 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 Gene3D G3DSA:3.30.470.20 191 299 1.1E-15 T 28-03-2018 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 119 1.5E-43 T 28-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 123 296 1.1E-71 T 28-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 Hamap MF_00162 Glutathione synthetase [gshB]. 1 315 159.328 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 Gene3D G3DSA:3.30.1490.20 137 190 3.7E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS22995 d2a938257f9d22d1e313b70763f98754 315 SUPERFAMILY SSF52440 1 121 4.32E-41 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS20910 d7d06ae339b51c474b067e45c4bc2201 174 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 15 170 2.7E-36 T 28-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 hmeg3_RS20910 d7d06ae339b51c474b067e45c4bc2201 174 SUPERFAMILY SSF52016 15 170 9.81E-20 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS20910 d7d06ae339b51c474b067e45c4bc2201 174 Gene3D G3DSA:3.20.19.10 9 174 6.5E-25 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS15130 a141692f1e8f6a288058311cd6182b67 502 SUPERFAMILY SSF53720 6 486 7.59E-146 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15130 a141692f1e8f6a288058311cd6182b67 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15130 a141692f1e8f6a288058311cd6182b67 502 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 485 1.2E-212 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 hmeg3_RS15130 a141692f1e8f6a288058311cd6182b67 502 Pfam PF00171 Aldehyde dehydrogenase family 18 481 6.2E-137 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15130 a141692f1e8f6a288058311cd6182b67 502 Gene3D G3DSA:3.40.309.10 268 463 2.3E-59 T 28-03-2018 hmeg3_RS15130 a141692f1e8f6a288058311cd6182b67 502 Gene3D G3DSA:3.40.605.10 1 267 9.0E-89 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20460 70b0588b631391f190660988267536fe 267 Gene3D G3DSA:1.10.3720.10 7 267 9.8E-34 T 28-03-2018 hmeg3_RS20460 70b0588b631391f190660988267536fe 267 SUPERFAMILY SSF161098 4 257 2.49E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS20460 70b0588b631391f190660988267536fe 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 264 1.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 Gene3D G3DSA:3.20.20.450 5 83 0.025 T 28-03-2018 IPR001633 EAL domain hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 Pfam PF08668 HDOD domain 232 339 5.8E-10 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 Gene3D G3DSA:3.20.20.450 84 207 2.2E-17 T 28-03-2018 IPR001633 EAL domain hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 PIRSF PIRSF003180 15 426 2.4E-109 T 28-03-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 Pfam PF00563 EAL domain 14 205 4.7E-12 T 28-03-2018 IPR001633 EAL domain hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 SUPERFAMILY SSF109604 196 422 1.19E-31 T 28-03-2018 hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 Gene3D G3DSA:1.10.3210.10 208 358 5.6E-13 T 28-03-2018 hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 SMART SM00052 2 210 1.0E-5 T 28-03-2018 IPR001633 EAL domain hmeg3_RS01630 89251a38293350ed9a2c254a99bd9f4e 434 SUPERFAMILY SSF141868 15 205 6.54E-30 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 2.7E-5 T 28-03-2018 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 2.7E-5 T 28-03-2018 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.2E-35 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 2.2E-35 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 2.2E-35 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 2.2E-35 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 89.968 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 Gene3D G3DSA:1.10.275.10 1 137 2.0E-59 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 Gene3D G3DSA:1.10.40.30 417 461 1.6E-26 T 28-03-2018 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 SUPERFAMILY SSF48557 4 461 1.12E-154 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 Pfam PF00206 Lyase 13 341 2.2E-111 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 459 3.7E-236 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 Pfam PF10415 Fumarase C C-terminus 407 460 1.0E-25 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS16005 91b26f4da6d2c601b9c6dec7015f05c7 462 Gene3D G3DSA:1.20.200.10 138 416 2.8E-88 T 28-03-2018 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 Pfam PF02803 Thiolase, C-terminal domain 275 397 3.5E-43 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 SUPERFAMILY SSF53901 4 272 8.02E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 Gene3D G3DSA:3.40.47.10 278 395 3.4E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 SUPERFAMILY SSF53901 276 397 7.88E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 396 3.3E-138 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 Gene3D G3DSA:3.40.47.10 1 143 6.4E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 Gene3D G3DSA:3.40.47.10 145 277 1.4E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 Pfam PF00108 Thiolase, N-terminal domain 9 267 4.6E-72 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 PIRSF PIRSF000429 2 398 3.9E-120 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS22345 4e034327bf43802cedd2e3d16ba4fdbb 398 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 hmeg3_RS17265 f962c297585d81f9b058ea612ce76564 279 Pfam PF01435 Peptidase family M48 82 262 8.6E-36 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 hmeg3_RS17265 f962c297585d81f9b058ea612ce76564 279 Gene3D G3DSA:3.30.2010.10 70 168 1.6E-24 T 28-03-2018 hmeg3_RS19075 d7bd8d834fac0f30c96fce8a13c44843 290 Gene3D G3DSA:3.40.50.1010 1 272 2.3E-8 T 28-03-2018 IPR029060 PIN domain-like hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 7.5E-23 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 SUPERFAMILY SSF64484 12 232 0.0 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 SUPERFAMILY SSF64484 349 945 0.0 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 SUPERFAMILY SSF64484 1058 1366 0.0 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:2.40.50.150 835 1064 1.4E-51 T 28-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 6.8E-32 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:3.90.1800.10 1293 1336 9.0E-12 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:2.40.270.10 1065 1268 4.5E-78 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1364 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF00562 RNA polymerase Rpb2, domain 6 725 1290 1.2E-156 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:2.40.50.100 721 801 6.7E-27 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF04561 RNA polymerase Rpb2, domain 2 156 227 3.4E-7 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF04561 RNA polymerase Rpb2, domain 2 356 460 3.0E-17 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:3.90.1100.10 651 719 8.7E-15 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:3.90.1100.10 19 266 5.8E-45 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Gene3D G3DSA:3.90.1100.10 382 650 4.7E-83 T 28-03-2018 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1368 12.148 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF04563 RNA polymerase beta subunit 27 506 4.7E-36 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22905 a49f92695648804bb1b0bd5f2b7cfcd4 1368 Pfam PF04560 RNA polymerase Rpb2, domain 7 1292 1366 1.0E-25 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 PIRSF PIRSF037677 15 875 1.8E-143 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Pfam PF01624 MutS domain I 22 133 3.0E-40 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Gene3D G3DSA:3.40.1170.10 10 144 2.1E-44 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 SUPERFAMILY SSF55271 18 129 7.59E-41 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 21 895 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 SMART SM00534 638 825 1.8E-115 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 SUPERFAMILY SSF48334 292 598 1.44E-78 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 SUPERFAMILY SSF52540 599 828 2.06E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Pfam PF05188 MutS domain II 153 277 1.7E-16 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Gene3D G3DSA:3.30.420.110 145 287 9.6E-19 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Pfam PF05192 MutS domain III 294 591 3.9E-32 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 SUPERFAMILY SSF53150 128 290 2.22E-27 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Gene3D G3DSA:3.40.50.300 599 865 2.1E-40 T 28-03-2018 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 21 889 24.17 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 719 735 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Pfam PF00488 MutS domain V 642 828 6.1E-84 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Pfam PF05190 MutS family domain IV 460 551 2.6E-30 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Gene3D G3DSA:1.10.1420.10 440 567 2.0E-30 T 28-03-2018 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 Gene3D G3DSA:1.10.1420.10 289 439 1.4E-31 T 28-03-2018 hmeg3_RS17100 c52396132d6576db74933230a7e07dee 899 SMART SM00533 312 623 3.1E-84 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 hmeg3_RS02975 125ccd1474a283d062a1305e18940de1 264 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 5 99 3.2E-7 T 28-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 hmeg3_RS02975 125ccd1474a283d062a1305e18940de1 264 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 156 256 5.2E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 hmeg3_RS02975 125ccd1474a283d062a1305e18940de1 264 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 257 2.1E-53 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 hmeg3_RS02975 125ccd1474a283d062a1305e18940de1 264 SUPERFAMILY SSF63848 154 260 6.15E-29 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 hmeg3_RS02975 125ccd1474a283d062a1305e18940de1 264 Gene3D G3DSA:2.160.20.70 136 264 1.3E-32 T 28-03-2018 hmeg3_RS02975 125ccd1474a283d062a1305e18940de1 264 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 261 24.319 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 SUPERFAMILY SSF58014 37 127 2.88E-24 T 28-03-2018 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 Gene3D G3DSA:3.90.20.20 2 128 3.3E-24 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 Pfam PF01025 GrpE 24 185 6.4E-47 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 PRINTS PR00773 GrpE protein signature 164 183 3.3E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 PRINTS PR00773 GrpE protein signature 85 100 3.3E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 PRINTS PR00773 GrpE protein signature 138 153 3.3E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 PRINTS PR00773 GrpE protein signature 57 73 3.3E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 Gene3D G3DSA:2.30.22.10 130 187 2.0E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 SUPERFAMILY SSF51064 131 186 6.41E-15 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 Hamap MF_01151 Protein GrpE [grpE]. 2 185 19.07 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS20390 efc1faf7c22d6006a38f338874ca063d 187 ProSitePatterns PS01071 grpE protein signature. 141 183 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 SMART SM00304 210 263 5.1E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 479 1.2E-56 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 SUPERFAMILY SSF58104 231 514 2.22E-76 T 28-03-2018 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 Gene3D G3DSA:1.10.287.1060 240 321 0.01 T 28-03-2018 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 SMART SM00283 264 511 1.6E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 Gene3D G3DSA:1.10.287.950 322 515 3.5E-51 T 28-03-2018 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 182 2.3E-15 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 1.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 1.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 11 36 1.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 1.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 1.0E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01005 d7b46a103e14d5522277cc174e84adb4 553 Gene3D G3DSA:1.20.120.30 19 184 2.4E-22 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS15340 5831556b908c9562864a18e367166b9d 375 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 346 1.1E-58 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 hmeg3_RS15340 5831556b908c9562864a18e367166b9d 375 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 348 2.1E-118 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 Gene3D G3DSA:2.40.150.20 1 122 1.9E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.2E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.866 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 SMART SM01374 1 122 4.5E-82 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.2E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 SUPERFAMILY SSF50193 1 122 4.45E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22810 00baea9080220ac8b4cfa68d04b19019 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 Gene3D G3DSA:1.10.10.10 118 222 9.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 SMART SM00862 144 217 1.8E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 Pfam PF00072 Response regulator receiver domain 3 111 4.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 SMART SM00448 1 111 1.8E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.6E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 SUPERFAMILY SSF52172 1 177 1.12E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10935 c8118f32ff0f81d9dd294721a87936e5 232 Gene3D G3DSA:3.40.50.2300 1 117 2.1E-32 T 28-03-2018 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 SMART SM00304 213 265 2.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 Pfam PF00672 HAMP domain 213 260 3.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 SMART SM00283 266 513 3.9E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 7.1E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 Gene3D G3DSA:1.20.120.30 25 187 6.1E-19 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 5.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 5.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 5.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 5.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 5.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 190 210 5.5E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 186 9.9E-35 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 SUPERFAMILY SSF58104 233 519 6.93E-78 T 28-03-2018 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 Gene3D G3DSA:1.10.287.950 326 517 5.9E-49 T 28-03-2018 hmeg3_RS12250 8b1242ed3edcdfd2b2aacc3a3ca65c63 580 Gene3D G3DSA:1.10.287.1060 240 325 0.31 T 28-03-2018 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 Gene3D G3DSA:2.40.30.10 1 98 6.0E-19 T 28-03-2018 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 267 275 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 237 309 8.0E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 SUPERFAMILY SSF52343 100 224 5.11E-30 T 28-03-2018 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 SUPERFAMILY SSF63380 3 98 8.6E-29 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 74 88 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 38 50 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 50 64 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 109 128 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 196 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 134 143 1.8E-43 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 Pfam PF00175 Oxidoreductase NAD-binding domain 110 201 2.3E-7 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 Gene3D G3DSA:3.10.20.30 220 318 4.1E-21 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 Gene3D G3DSA:3.40.50.80 99 219 3.6E-21 T 28-03-2018 hmeg3_RS01215 e0184a70b82ddefbf81c46ed10b1feb6 318 SUPERFAMILY SSF54292 210 317 2.49E-30 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 SUPERFAMILY SSF88946 10 86 3.88E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 Pfam PF08281 Sigma-70, region 4 109 154 3.7E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 Pfam PF04542 Sigma-70 region 2 11 76 2.0E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 Gene3D G3DSA:1.10.10.10 104 165 5.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 155 5.6E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 SUPERFAMILY SSF88659 101 157 1.55E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12050 95889c4c1d8ced567d38db74f3ac27e6 171 Gene3D G3DSA:1.10.1740.10 5 78 1.6E-14 T 28-03-2018 hmeg3_RS17525 c0688b88501cf94beca2155f81ef98a9 445 SUPERFAMILY SSF53850 49 444 1.25E-55 T 28-03-2018 hmeg3_RS17525 c0688b88501cf94beca2155f81ef98a9 445 Pfam PF13416 Bacterial extracellular solute-binding protein 71 382 4.6E-36 T 28-03-2018 hmeg3_RS17525 c0688b88501cf94beca2155f81ef98a9 445 Gene3D G3DSA:3.40.190.10 160 442 9.6E-34 T 28-03-2018 hmeg3_RS01235 a23c6a8a108484f7bffc38b62bd7a443 172 Gene3D G3DSA:2.60.130.10 1 171 5.8E-26 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS01235 a23c6a8a108484f7bffc38b62bd7a443 172 SUPERFAMILY SSF49482 4 170 6.93E-22 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 Gene3D G3DSA:3.40.50.2300 208 366 4.3E-23 T 28-03-2018 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 SUPERFAMILY SSF53822 34 383 3.7E-83 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 Gene3D G3DSA:3.40.50.2300 31 207 5.1E-30 T 28-03-2018 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 35 51 1.0E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 342 357 1.0E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 97 107 1.0E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 288 301 1.0E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01220 79bf866e7e2cc42ce43b8ed348371180 395 Pfam PF13458 Periplasmic binding protein 34 373 1.1E-66 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 3.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 3.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 5.7E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 SMART SM00866 93 237 1.3E-17 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 SUPERFAMILY SSF46785 4 81 1.21E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 SMART SM00345 13 72 1.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 SUPERFAMILY SSF64288 60 244 4.4E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 Gene3D G3DSA:1.10.10.10 2 74 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 Pfam PF07702 UTRA domain 106 236 5.8E-16 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 hmeg3_RS16360 28a55eef760652ae216eb0fe6700cc37 245 Gene3D G3DSA:3.40.1410.10 78 245 1.6E-30 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain hmeg3_RS07055 178764d0a3c136dd517ff612314eb091 144 SUPERFAMILY SSF53098 1 141 7.46E-58 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS07055 178764d0a3c136dd517ff612314eb091 144 Gene3D G3DSA:3.30.420.10 1 144 1.6E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS07055 178764d0a3c136dd517ff612314eb091 144 Hamap MF_00042 Ribonuclease H [rnhA]. 1 144 33.507 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 hmeg3_RS07055 178764d0a3c136dd517ff612314eb091 144 Pfam PF00075 RNase H 3 140 6.5E-51 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 Gene3D G3DSA:1.10.1240.20 403 469 1.3E-20 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 Gene3D G3DSA:1.10.530.10 472 641 8.6E-34 T 28-03-2018 hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 SUPERFAMILY SSF48435 38 476 2.35E-109 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 SUPERFAMILY SSF53955 489 639 2.25E-43 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 Pfam PF14718 Soluble lytic murein transglycosylase L domain 406 466 1.1E-6 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 Pfam PF01464 Transglycosylase SLT domain 491 589 1.1E-22 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 hmeg3_RS02900 14c7b12308dd9bae78b58c2a42be68d3 652 Gene3D G3DSA:1.25.20.10 34 387 1.6E-38 T 28-03-2018 hmeg3_RS23690 aaa09dd5a3c604279facbc995f9d562d 254 Gene3D G3DSA:1.10.3720.10 7 253 5.1E-21 T 28-03-2018 hmeg3_RS23690 aaa09dd5a3c604279facbc995f9d562d 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 247 1.6E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23690 aaa09dd5a3c604279facbc995f9d562d 254 SUPERFAMILY SSF161098 54 239 4.84E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS15225 704d4c3208f3b098f2e1015c87a7b0a4 170 Gene3D G3DSA:3.30.1450.10 32 91 0.1 T 28-03-2018 hmeg3_RS15225 704d4c3208f3b098f2e1015c87a7b0a4 170 Pfam PF04355 SmpA / OmlA family 96 138 2.0E-7 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 hmeg3_RS15225 704d4c3208f3b098f2e1015c87a7b0a4 170 Gene3D G3DSA:3.30.1450.10 92 167 1.1E-14 T 28-03-2018 hmeg3_RS14730 f66ca8c6df62e9750a9917cf9d5384a4 416 Gene3D G3DSA:1.10.443.10 52 259 1.4E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS14730 f66ca8c6df62e9750a9917cf9d5384a4 416 SUPERFAMILY SSF56349 59 122 6.28E-5 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS14730 f66ca8c6df62e9750a9917cf9d5384a4 416 SUPERFAMILY SSF56349 202 261 6.28E-5 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS11960 fa084e34a471c787a9de0b81cddfbc13 107 Gene3D G3DSA:3.30.70.120 1 107 1.1E-23 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal hmeg3_RS11960 fa084e34a471c787a9de0b81cddfbc13 107 SUPERFAMILY SSF54913 1 100 3.45E-25 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta hmeg3_RS11960 fa084e34a471c787a9de0b81cddfbc13 107 Pfam PF02641 Uncharacterized ACR, COG1993 6 85 1.6E-14 T 28-03-2018 IPR003793 Domain of unknown function DUF190 hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 81 3.5E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 Pfam PF07729 FCD domain 100 225 4.8E-25 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 Gene3D G3DSA:1.20.120.530 99 240 5.0E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 Gene3D G3DSA:1.10.10.10 10 82 6.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 SUPERFAMILY SSF48008 98 228 1.07E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 SUPERFAMILY SSF46785 15 85 5.18E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 7.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 7.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 SMART SM00345 22 81 1.4E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS14395 d6fb233ed6175044aeb67ce3c075f106 246 SMART SM00895 100 225 1.1E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS16890 7b5f04058fb8e6b1cfb164e2cb1b0c61 399 Gene3D G3DSA:1.25.40.10 229 395 1.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS16890 7b5f04058fb8e6b1cfb164e2cb1b0c61 399 Pfam PF07219 HemY protein N-terminus 26 131 2.2E-30 T 28-03-2018 IPR010817 HemY, N-terminal hmeg3_RS16890 7b5f04058fb8e6b1cfb164e2cb1b0c61 399 SUPERFAMILY SSF48452 262 392 3.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS16890 7b5f04058fb8e6b1cfb164e2cb1b0c61 399 Gene3D G3DSA:1.25.40.10 53 228 0.088 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS16890 7b5f04058fb8e6b1cfb164e2cb1b0c61 399 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 2 392 7.8E-121 T 28-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 hmeg3_RS05230 2062b5e7675fdad46e73fb97fe498f06 428 Gene3D G3DSA:3.40.50.2300 31 196 7.0E-36 T 28-03-2018 hmeg3_RS05230 2062b5e7675fdad46e73fb97fe498f06 428 SUPERFAMILY SSF53822 34 426 2.09E-74 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS05230 2062b5e7675fdad46e73fb97fe498f06 428 Pfam PF13458 Periplasmic binding protein 34 377 2.0E-53 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS05230 2062b5e7675fdad46e73fb97fe498f06 428 Gene3D G3DSA:3.40.50.2300 317 392 0.15 T 28-03-2018 hmeg3_RS05230 2062b5e7675fdad46e73fb97fe498f06 428 Gene3D G3DSA:3.40.50.2300 197 316 3.3E-17 T 28-03-2018 hmeg3_RS03710 689264e0828d7685306fb6639ee60893 385 Pfam PF01266 FAD dependent oxidoreductase 16 358 1.3E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS03710 689264e0828d7685306fb6639ee60893 385 Gene3D G3DSA:3.50.50.60 7 385 4.0E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03710 689264e0828d7685306fb6639ee60893 385 SUPERFAMILY SSF51905 15 227 8.09E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03710 689264e0828d7685306fb6639ee60893 385 SUPERFAMILY SSF51905 320 374 8.09E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 SUPERFAMILY SSF109709 122 227 2.41E-33 T 28-03-2018 hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 SUPERFAMILY SSF110849 36 131 1.6E-26 T 28-03-2018 IPR003115 ParB/Sulfiredoxin hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 32 213 8.8E-57 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 Pfam PF02195 ParB-like nuclease domain 38 128 2.4E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 Gene3D G3DSA:1.10.10.730 130 177 2.0E-19 T 28-03-2018 hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 Gene3D G3DSA:3.90.1530.10 26 129 1.0E-31 T 28-03-2018 hmeg3_RS24155 c2549c30ef4fa4e34170f2365ea0546c 302 SMART SM00470 35 129 5.9E-31 T 28-03-2018 IPR003115 ParB/Sulfiredoxin hmeg3_RS10510 1e87a06e7f96827ea4b61ab13bf6326d 152 Pfam PF05229 Spore Coat Protein U domain 18 149 5.7E-32 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS10510 1e87a06e7f96827ea4b61ab13bf6326d 152 Gene3D G3DSA:2.60.40.1090 16 152 9.6E-4 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS10510 1e87a06e7f96827ea4b61ab13bf6326d 152 SMART SM00972 91 149 9.7E-20 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS03545 e7367f25d27aa5ff399d3474d099a14d 228 Pfam PF09365 Conserved hypothetical protein (DUF2461) 7 218 5.3E-61 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 hmeg3_RS03545 e7367f25d27aa5ff399d3474d099a14d 228 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 6 222 5.0E-57 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 hmeg3_RS03545 e7367f25d27aa5ff399d3474d099a14d 228 PIRSF PIRSF028451 1 224 7.3E-56 T 28-03-2018 IPR015996 Uncharacterised conserved protein UCP028451 hmeg3_RS02640 19f3768822cc2bcac7757c5c0a6f70d9 180 Pfam PF00419 Fimbrial protein 27 180 6.8E-15 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS02640 19f3768822cc2bcac7757c5c0a6f70d9 180 Gene3D G3DSA:2.60.40.1090 25 180 9.6E-33 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS02640 19f3768822cc2bcac7757c5c0a6f70d9 180 SUPERFAMILY SSF49401 26 180 4.82E-29 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 387 46.758 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 Pfam PF13288 DXP reductoisomerase C-terminal domain 266 382 8.0E-41 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 SUPERFAMILY SSF51735 3 150 1.5E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 SUPERFAMILY SSF69055 296 387 9.02E-29 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 234 2.5E-37 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 PIRSF PIRSF006205 1 389 9.0E-155 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 Gene3D G3DSA:3.40.50.720 1 150 7.8E-51 T 28-03-2018 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 1.7E-48 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 384 4.0E-153 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 SUPERFAMILY SSF55347 126 269 8.5E-61 T 28-03-2018 hmeg3_RS09965 a629d8339cbe947b6369135f8519c79e 390 Gene3D G3DSA:1.10.1740.10 307 389 2.5E-27 T 28-03-2018 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 Gene3D G3DSA:3.30.565.10 331 498 8.6E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 494 3.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 SUPERFAMILY SSF47384 246 327 2.55E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 Pfam PF00672 HAMP domain 212 259 3.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 SMART SM00387 373 496 2.3E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 SUPERFAMILY SSF55874 316 495 3.54E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 SMART SM00304 210 262 2.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 493 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 474 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 449 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 435 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 SMART SM00388 263 327 4.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 SUPERFAMILY SSF158472 212 258 1.07E-8 T 28-03-2018 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 Gene3D G3DSA:3.30.450.20 151 267 0.0024 T 28-03-2018 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 Gene3D G3DSA:1.10.287.130 268 322 7.2E-14 T 28-03-2018 hmeg3_RS06475 4f0bb9250b00f0432860fd4f1adc781e 505 Pfam PF00512 His Kinase A (phospho-acceptor) domain 264 327 1.3E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS16225 b105610be9fdc4ac70841b9938071946 199 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 35 187 7.3E-9 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like hmeg3_RS16225 b105610be9fdc4ac70841b9938071946 199 SUPERFAMILY SSF89392 21 185 7.85E-13 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX hmeg3_RS16225 b105610be9fdc4ac70841b9938071946 199 Gene3D G3DSA:2.50.20.10 18 191 1.3E-13 T 28-03-2018 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Pfam PF02743 Cache domain 40 261 5.7E-12 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 SMART SM00387 429 540 1.7E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 SMART SM00388 317 382 1.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 SUPERFAMILY SSF47384 300 383 2.94E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Gene3D G3DSA:3.30.450.20 159 278 3.8E-11 T 28-03-2018 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 430 538 3.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Pfam PF00512 His Kinase A (phospho-acceptor) domain 318 382 2.0E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Gene3D G3DSA:3.30.450.20 23 158 2.2E-12 T 28-03-2018 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Gene3D G3DSA:3.30.565.10 386 548 2.8E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 518 8.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 537 8.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 493 8.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 479 8.2E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 Gene3D G3DSA:1.10.287.130 308 377 1.8E-15 T 28-03-2018 hmeg3_RS11530 aee5e35cfd9e7e66a71ef8b2d40be34f 551 SUPERFAMILY SSF55874 372 538 4.98E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 SUPERFAMILY SSF51735 6 254 2.29E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 7.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 1.7E-58 T 28-03-2018 hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 Gene3D G3DSA:3.40.50.720 1 52 8.0E-7 T 28-03-2018 hmeg3_RS17670 f13cfe3b3854c68252d798e52ddc2b78 260 Gene3D G3DSA:3.40.50.720 53 258 8.9E-60 T 28-03-2018 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 Gene3D G3DSA:3.40.190.10 181 267 1.3E-19 T 28-03-2018 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 SUPERFAMILY SSF53850 92 298 1.99E-40 T 28-03-2018 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 Pfam PF03466 LysR substrate binding domain 89 292 1.1E-40 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 SUPERFAMILY SSF46785 2 83 1.52E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 Gene3D G3DSA:1.10.10.10 1 83 6.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 Gene3D G3DSA:3.40.190.10 90 180 1.4E-22 T 28-03-2018 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 4.6E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS15285 f7d99551292ab7776b70ea75f2298d1a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11140 a0705cc5bd34284c45fc90247afc2dda 504 SMART SM00267 309 483 1.7E-64 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11140 a0705cc5bd34284c45fc90247afc2dda 504 Gene3D G3DSA:3.30.70.270 304 484 1.9E-60 T 28-03-2018 hmeg3_RS11140 a0705cc5bd34284c45fc90247afc2dda 504 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 482 5.0E-44 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS11140 a0705cc5bd34284c45fc90247afc2dda 504 SUPERFAMILY SSF55073 326 485 4.0E-50 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS11140 a0705cc5bd34284c45fc90247afc2dda 504 Pfam PF00990 Diguanylate cyclase, GGDEF domain 321 477 2.9E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18930 19fe3574f0c6f23ccf9c7b2f93cab7bc 304 SUPERFAMILY SSF52821 107 245 1.03E-24 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS18930 19fe3574f0c6f23ccf9c7b2f93cab7bc 304 Gene3D G3DSA:3.40.250.10 118 239 6.5E-20 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS18930 19fe3574f0c6f23ccf9c7b2f93cab7bc 304 Pfam PF00581 Rhodanese-like domain 133 225 3.5E-5 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS18930 19fe3574f0c6f23ccf9c7b2f93cab7bc 304 Hamap MF_00469 UPF0176 protein YceA [yceA]. 13 269 36.543 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 hmeg3_RS18930 19fe3574f0c6f23ccf9c7b2f93cab7bc 304 SMART SM00450 130 231 8.9E-11 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 Pfam PF05036 Sporulation related domain 319 393 5.5E-11 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 Gene3D G3DSA:3.30.70.1070 316 395 2.4E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 14 230 23.964 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 Pfam PF03330 Lytic transglycolase 138 222 1.7E-23 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 140 229 6.6E-38 T 28-03-2018 IPR012997 Rare lipoprotein A hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 SUPERFAMILY SSF110997 320 393 1.96E-8 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 SUPERFAMILY SSF50685 138 220 3.98E-9 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain hmeg3_RS00740 0611037e9475c653fae9f46c6aaf0bef 395 Gene3D G3DSA:2.40.40.10 120 229 5.0E-22 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 SMART SM00342 229 312 1.3E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 Gene3D G3DSA:1.10.10.60 208 268 5.8E-13 T 28-03-2018 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 Pfam PF12833 Helix-turn-helix domain 235 313 1.9E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 Gene3D G3DSA:1.10.10.60 269 329 2.0E-15 T 28-03-2018 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 SUPERFAMILY SSF46689 266 316 9.86E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 SUPERFAMILY SSF51182 38 85 1.34E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 312 7.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 296 7.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 SUPERFAMILY SSF46689 212 262 3.23E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 Gene3D G3DSA:2.60.120.280 15 197 2.2E-13 T 28-03-2018 hmeg3_RS20665 cf13165d0fb1ebebc0e395cd0ba7930f 331 Pfam PF12852 Cupin 6 196 9.0E-35 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 PIRSF PIRSF037238 32 413 2.0E-104 T 28-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 Pfam PF07687 Peptidase dimerisation domain 212 310 8.3E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 SUPERFAMILY SSF53187 335 412 1.34E-47 T 28-03-2018 hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 SUPERFAMILY SSF53187 33 223 1.34E-47 T 28-03-2018 hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 SUPERFAMILY SSF55031 215 326 1.7E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 Pfam PF01546 Peptidase family M20/M25/M40 110 409 2.2E-29 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS12920 e4ada8b12437ec4a6d7aecf36be04cef 416 Gene3D G3DSA:3.40.630.10 27 416 1.3E-50 T 28-03-2018 hmeg3_RS16385 3f60a5c8253330089f9ff618d52004ec 321 SUPERFAMILY SSF53850 1 274 1.14E-59 T 28-03-2018 hmeg3_RS16385 3f60a5c8253330089f9ff618d52004ec 321 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 273 1.7E-49 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS16385 3f60a5c8253330089f9ff618d52004ec 321 SMART SM00062 43 275 6.4E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS16385 3f60a5c8253330089f9ff618d52004ec 321 Gene3D G3DSA:3.40.190.10 170 282 4.7E-11 T 28-03-2018 hmeg3_RS16385 3f60a5c8253330089f9ff618d52004ec 321 Gene3D G3DSA:3.40.190.10 2 169 6.9E-33 T 28-03-2018 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 SUPERFAMILY SSF53187 292 373 1.18E-63 T 28-03-2018 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 SUPERFAMILY SSF53187 3 178 1.18E-63 T 28-03-2018 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 Pfam PF01546 Peptidase family M20/M25/M40 62 372 5.1E-44 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 373 1.2E-159 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 Gene3D G3DSA:3.40.630.10 1 280 2.9E-60 T 28-03-2018 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 SUPERFAMILY SSF55031 179 288 2.09E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 375 51.23 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 hmeg3_RS09850 e802400584ab0315a50d81ea5ed8c717 375 Pfam PF07687 Peptidase dimerisation domain 175 282 1.9E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS21125 4c142b662dd0587883fa9f88b874f3b1 411 Pfam PF00529 HlyD membrane-fusion protein of T1SS 48 360 1.5E-6 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS21125 4c142b662dd0587883fa9f88b874f3b1 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 375 4.4E-90 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS21125 4c142b662dd0587883fa9f88b874f3b1 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 294 4.7E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS21125 4c142b662dd0587883fa9f88b874f3b1 411 SUPERFAMILY SSF111369 52 300 7.19E-84 T 28-03-2018 hmeg3_RS21125 4c142b662dd0587883fa9f88b874f3b1 411 Gene3D G3DSA:1.20.1600.10 14 319 2.6E-34 T 28-03-2018 hmeg3_RS09280 d7a541f07708d7e33b3bf0898fe91afa 142 Gene3D G3DSA:1.20.5.1000 28 76 2.3E-5 T 28-03-2018 hmeg3_RS09280 d7a541f07708d7e33b3bf0898fe91afa 142 Pfam PF04977 Septum formation initiator 11 88 6.8E-28 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 hmeg3_RS09280 d7a541f07708d7e33b3bf0898fe91afa 142 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 35.181 T 28-03-2018 IPR023081 Cell division protein FtsB hmeg3_RS09085 ed344289907f415e80c26ed49b4dbd70 214 Pfam PF12804 MobA-like NTP transferase domain 12 168 5.1E-33 T 28-03-2018 IPR025877 MobA-like NTP transferase hmeg3_RS09085 ed344289907f415e80c26ed49b4dbd70 214 Gene3D G3DSA:3.90.550.10 6 206 1.0E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS09085 ed344289907f415e80c26ed49b4dbd70 214 SUPERFAMILY SSF53448 10 199 3.6E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS09085 ed344289907f415e80c26ed49b4dbd70 214 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 10 199 3.0E-64 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 hmeg3_RS09085 ed344289907f415e80c26ed49b4dbd70 214 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 8 202 27.357 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 hmeg3_RS02715 11c006d56ff5ce7b528bb88435397181 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 401 587 8.0E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02715 11c006d56ff5ce7b528bb88435397181 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 294 5.0E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02715 11c006d56ff5ce7b528bb88435397181 603 Gene3D G3DSA:1.10.3720.10 318 601 1.5E-29 T 28-03-2018 hmeg3_RS02715 11c006d56ff5ce7b528bb88435397181 603 Gene3D G3DSA:1.10.3720.10 22 302 2.3E-33 T 28-03-2018 hmeg3_RS02715 11c006d56ff5ce7b528bb88435397181 603 SUPERFAMILY SSF161098 19 302 1.83E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02715 11c006d56ff5ce7b528bb88435397181 603 SUPERFAMILY SSF161098 316 597 1.7E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 Gene3D G3DSA:1.10.10.10 2 68 7.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 130 140 1.4E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 169 181 1.4E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 141 152 1.4E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 SUPERFAMILY SSF46785 3 70 3.34E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 Pfam PF00717 Peptidase S24-like 133 198 9.3E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 Hamap MF_00015 LexA repressor [lexA]. 3 218 31.493 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 Gene3D G3DSA:2.10.109.10 99 218 1.2E-22 T 28-03-2018 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 Pfam PF01726 LexA DNA binding domain 1 65 2.5E-28 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 TIGRFAM TIGR00498 lexA: repressor LexA 1 217 6.3E-71 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 hmeg3_RS08375 c91f2bc3f05dfb0bc1545571bdcd95a1 219 SUPERFAMILY SSF51306 94 216 1.36E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C hmeg3_RS13985 cc8ade68eb2a6c28a78afad854dfa2db 310 SUPERFAMILY SSF53474 108 297 7.34E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS13985 cc8ade68eb2a6c28a78afad854dfa2db 310 Pfam PF07819 PGAP1-like protein 158 214 4.3E-9 T 28-03-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 hmeg3_RS13985 cc8ade68eb2a6c28a78afad854dfa2db 310 Gene3D G3DSA:3.40.50.1820 103 309 2.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05735 eadad72d6d09dbc6c3fd6bf69f4fed2b 262 Gene3D G3DSA:3.40.190.10 26 178 3.2E-29 T 28-03-2018 hmeg3_RS05735 eadad72d6d09dbc6c3fd6bf69f4fed2b 262 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 254 6.1E-45 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS05735 eadad72d6d09dbc6c3fd6bf69f4fed2b 262 SUPERFAMILY SSF53850 1 255 7.76E-51 T 28-03-2018 hmeg3_RS05735 eadad72d6d09dbc6c3fd6bf69f4fed2b 262 Gene3D G3DSA:3.40.190.10 179 259 8.2E-11 T 28-03-2018 hmeg3_RS05735 eadad72d6d09dbc6c3fd6bf69f4fed2b 262 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS05735 eadad72d6d09dbc6c3fd6bf69f4fed2b 262 SMART SM00062 37 256 3.0E-38 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 Gene3D G3DSA:1.10.760.10 179 317 1.3E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 SUPERFAMILY SSF46626 28 157 2.12E-24 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 PIRSF PIRSF000018 2 438 7.9E-162 T 28-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 SUPERFAMILY SSF46626 331 435 6.75E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 Pfam PF00034 Cytochrome c 34 131 3.8E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 Pfam PF00034 Cytochrome c 190 288 1.6E-4 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 PRINTS PR00605 Class IC cytochrome C signature 391 413 3.2E-6 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 PRINTS PR00605 Class IC cytochrome C signature 338 349 3.2E-6 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 330 413 6.2E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 Gene3D G3DSA:1.10.760.10 318 438 3.3E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 SUPERFAMILY SSF46626 180 290 3.69E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17695 b9cbaabae2b14b1e2ccccd2b80886f7d 438 Gene3D G3DSA:1.10.760.10 3 147 3.3E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS09105 7f36bad04a685b26385342a8521d053b 219 Gene3D G3DSA:1.10.150.240 32 75 4.0E-17 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 hmeg3_RS09105 7f36bad04a685b26385342a8521d053b 219 SUPERFAMILY SSF56784 6 216 7.86E-55 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS09105 7f36bad04a685b26385342a8521d053b 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 185 3.8E-33 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS09105 7f36bad04a685b26385342a8521d053b 219 Gene3D G3DSA:3.40.50.1000 76 219 5.8E-28 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS09105 7f36bad04a685b26385342a8521d053b 219 Gene3D G3DSA:3.40.50.1000 1 31 0.066 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS09105 7f36bad04a685b26385342a8521d053b 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 180 4.4E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS15390 36b54620ebfb83055219ea8d883d072c 459 Gene3D G3DSA:1.20.1250.20 255 445 9.5E-14 T 28-03-2018 hmeg3_RS15390 36b54620ebfb83055219ea8d883d072c 459 SUPERFAMILY SSF103473 27 450 9.94E-76 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS15390 36b54620ebfb83055219ea8d883d072c 459 Gene3D G3DSA:1.20.1250.20 28 237 3.4E-37 T 28-03-2018 hmeg3_RS15390 36b54620ebfb83055219ea8d883d072c 459 Pfam PF07690 Major Facilitator Superfamily 45 408 2.1E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS09795 1930046d15e1e71818bdf6ae5ec978c2 420 SUPERFAMILY SSF103473 3 407 6.93E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS09795 1930046d15e1e71818bdf6ae5ec978c2 420 Gene3D G3DSA:1.20.1250.20 1 208 9.3E-17 T 28-03-2018 hmeg3_RS09795 1930046d15e1e71818bdf6ae5ec978c2 420 Gene3D G3DSA:1.20.1250.20 220 412 7.6E-9 T 28-03-2018 hmeg3_RS09795 1930046d15e1e71818bdf6ae5ec978c2 420 Pfam PF07690 Major Facilitator Superfamily 9 342 3.8E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS11525 2637d861add24f2b56084006d90c974e 130 Gene3D G3DSA:1.20.120.160 3 115 1.7E-13 T 28-03-2018 hmeg3_RS11525 2637d861add24f2b56084006d90c974e 130 SUPERFAMILY SSF47226 5 110 1.27E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS11525 2637d861add24f2b56084006d90c974e 130 Pfam PF01627 Hpt domain 27 89 7.8E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 Gene3D G3DSA:3.40.50.2300 18 152 5.4E-10 T 28-03-2018 hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 Gene3D G3DSA:1.10.10.10 153 204 3.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 SMART SM01012 148 203 9.9E-24 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 Pfam PF03861 ANTAR domain 154 203 1.9E-19 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 PIRSF PIRSF036382 20 210 9.3E-57 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 Pfam PF00072 Response regulator receiver domain 39 127 1.1E-4 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18185 caec23beba7a5202451fe1b68390f273 210 SUPERFAMILY SSF52172 28 203 1.46E-40 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS24300 f6728764362b5ec7007caf95af853270 103 ProDom PD052090 YDCA PRECURSOR SIGNAL ECS2024 19 55 1.0E-7 T 28-03-2018 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Gene3D G3DSA:1.10.150.20 442 484 9.3E-5 T 28-03-2018 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 29.091 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SUPERFAMILY SSF54814 202 280 3.66E-29 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SUPERFAMILY SSF47794 353 416 3.61E-16 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Pfam PF13184 NusA-like KH domain 232 299 1.5E-25 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SUPERFAMILY SSF69705 1 129 4.97E-35 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SUPERFAMILY SSF47794 426 483 1.32E-5 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Gene3D G3DSA:3.30.1480.10 1 132 4.2E-39 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SMART SM00316 136 202 4.0E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 5.6E-21 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 344 3.2E-120 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Gene3D G3DSA:3.30.300.20 201 278 2.9E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SUPERFAMILY SSF50249 136 201 1.33E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Gene3D G3DSA:1.10.150.20 355 423 8.1E-12 T 28-03-2018 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Pfam PF08529 NusA N-terminal domain 5 127 1.9E-33 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 SUPERFAMILY SSF54814 281 344 3.4E-15 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Gene3D G3DSA:3.30.300.20 280 350 5.3E-14 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Pfam PF00575 S1 RNA binding domain 140 196 6.1E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS05585 01ccf807287891bb45d79ba327ed453e 520 Gene3D G3DSA:2.40.50.140 139 200 4.3E-14 T 28-03-2018 hmeg3_RS18410 b9a175d4f674983276aa98c6d95fb507 457 Pfam PF13742 OB-fold nucleic acid binding domain 22 113 1.0E-29 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 hmeg3_RS18410 b9a175d4f674983276aa98c6d95fb507 457 Gene3D G3DSA:2.40.50.140 20 124 2.2E-5 T 28-03-2018 hmeg3_RS18410 b9a175d4f674983276aa98c6d95fb507 457 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 18 450 28.57 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS18410 b9a175d4f674983276aa98c6d95fb507 457 Pfam PF02601 Exonuclease VII, large subunit 137 446 3.4E-100 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 hmeg3_RS18410 b9a175d4f674983276aa98c6d95fb507 457 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 23 448 3.5E-145 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS01240 bc7f8c9119555a88cce4fe9e7069772c 230 Gene3D G3DSA:2.60.130.10 3 229 2.1E-57 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS01240 bc7f8c9119555a88cce4fe9e7069772c 230 Pfam PF00775 Dioxygenase 55 222 2.1E-55 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 hmeg3_RS01240 bc7f8c9119555a88cce4fe9e7069772c 230 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 9 32 7.6E-9 T 28-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 hmeg3_RS01240 bc7f8c9119555a88cce4fe9e7069772c 230 SUPERFAMILY SSF49482 13 227 3.66E-67 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS01240 bc7f8c9119555a88cce4fe9e7069772c 230 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 12 228 3.2E-97 T 28-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 hmeg3_RS01240 bc7f8c9119555a88cce4fe9e7069772c 230 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 73 101 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 Gene3D G3DSA:3.40.190.10 192 278 3.5E-21 T 28-03-2018 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 Gene3D G3DSA:1.10.10.10 15 98 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 77 4.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 SUPERFAMILY SSF53850 105 309 2.35E-39 T 28-03-2018 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 Pfam PF03466 LysR substrate binding domain 104 307 1.1E-35 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 SUPERFAMILY SSF46785 18 125 1.59E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23320 0d73ae3ed5007a32318b1e428d2b6723 318 Gene3D G3DSA:3.40.190.10 106 191 1.1E-15 T 28-03-2018 hmeg3_RS16105 53ade9f5c169a2b4d300738c3d116aa6 530 Pfam PF00563 EAL domain 267 499 3.2E-59 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16105 53ade9f5c169a2b4d300738c3d116aa6 530 SUPERFAMILY SSF141868 267 512 1.83E-71 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16105 53ade9f5c169a2b4d300738c3d116aa6 530 SMART SM00052 261 505 2.1E-91 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16105 53ade9f5c169a2b4d300738c3d116aa6 530 Gene3D G3DSA:3.20.20.450 260 516 8.7E-77 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16105 53ade9f5c169a2b4d300738c3d116aa6 530 Pfam PF12792 CSS motif domain associated with EAL 37 215 6.7E-26 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 Pfam PF00005 ABC transporter 37 179 4.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 Gene3D G3DSA:3.40.50.300 18 306 3.5E-74 T 28-03-2018 hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 Gene3D G3DSA:2.40.50.140 307 364 0.0022 T 28-03-2018 hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 SUPERFAMILY SSF50331 256 376 1.53E-7 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 SUPERFAMILY SSF52540 22 260 1.24E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 Pfam PF08402 TOBE domain 300 376 5.6E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 SMART SM00382 46 229 1.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10725 d7e683e405949f73aece543947a2faef 377 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 20 377 1.9E-158 T 28-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 hmeg3_RS13440 f775d75187a2e83bfee55278722ab93d 209 SUPERFAMILY SSF53335 35 197 2.89E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS13440 f775d75187a2e83bfee55278722ab93d 209 Pfam PF13649 Methyltransferase domain 54 143 3.0E-15 T 28-03-2018 hmeg3_RS13440 f775d75187a2e83bfee55278722ab93d 209 Gene3D G3DSA:3.40.50.150 15 208 3.3E-32 T 28-03-2018 hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 Gene3D G3DSA:1.20.58.220 28 144 3.3E-17 T 28-03-2018 hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 34 247 6.9E-51 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 Gene3D G3DSA:1.20.58.220 146 262 7.7E-21 T 28-03-2018 hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 Pfam PF01895 PhoU domain 50 132 1.1E-10 T 28-03-2018 IPR026022 PhoU domain hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 Pfam PF01895 PhoU domain 155 237 8.5E-13 T 28-03-2018 IPR026022 PhoU domain hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 PIRSF PIRSF003107 29 250 8.6E-50 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 hmeg3_RS02305 691e2bee4b4e1e994588bd2c2eebbd20 262 SUPERFAMILY SSF109755 34 253 2.3E-51 T 28-03-2018 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 SUPERFAMILY SSF100934 508 619 1.67E-32 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 Gene3D G3DSA:2.60.34.10 391 532 1.1E-48 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 Gene3D G3DSA:3.30.420.40 209 362 3.8E-38 T 28-03-2018 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 SUPERFAMILY SSF53067 199 379 7.78E-49 T 28-03-2018 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 335 349 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 620 43.402 T 28-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 204 217 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 SUPERFAMILY SSF100920 388 541 2.75E-49 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 Pfam PF00012 Hsp70 protein 21 603 3.6E-184 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 SUPERFAMILY SSF53067 19 195 1.42E-53 T 28-03-2018 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 Gene3D G3DSA:1.20.1270.10 533 619 3.2E-11 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 619 1.5E-278 T 28-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 470 486 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 48 60 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 210 220 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 332 348 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 20 33 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 363 383 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 389 408 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 PRINTS PR00301 70kDa heat shock protein signature 151 171 3.5E-56 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 hmeg3_RS15520 95f9ce43e7a89766f04f34232f4ca6b4 621 Gene3D G3DSA:3.30.420.40 19 208 3.6E-59 T 28-03-2018 hmeg3_RS20325 b3e74e2a2810f80577e61f793db88873 185 SMART SM00260 21 162 1.1E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20325 b3e74e2a2810f80577e61f793db88873 185 SUPERFAMILY SSF50341 22 165 6.02E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20325 b3e74e2a2810f80577e61f793db88873 185 Gene3D G3DSA:2.40.50.180 33 102 3.9E-17 T 28-03-2018 hmeg3_RS20325 b3e74e2a2810f80577e61f793db88873 185 Pfam PF01584 CheW-like domain 25 163 1.2E-32 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20325 b3e74e2a2810f80577e61f793db88873 185 Gene3D G3DSA:2.40.50.180 145 180 0.21 T 28-03-2018 hmeg3_RS20325 b3e74e2a2810f80577e61f793db88873 185 Gene3D G3DSA:2.30.30.40 103 144 8.9E-14 T 28-03-2018 hmeg3_RS23585 c96d7d83e8816539edefb43cd13acbf9 548 Gene3D G3DSA:3.20.20.450 260 516 3.7E-83 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23585 c96d7d83e8816539edefb43cd13acbf9 548 SMART SM00052 261 505 3.5E-100 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23585 c96d7d83e8816539edefb43cd13acbf9 548 Pfam PF00563 EAL domain 268 499 6.7E-63 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23585 c96d7d83e8816539edefb43cd13acbf9 548 Pfam PF12792 CSS motif domain associated with EAL 37 236 9.6E-29 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain hmeg3_RS23585 c96d7d83e8816539edefb43cd13acbf9 548 SUPERFAMILY SSF141868 267 513 6.93E-76 T 28-03-2018 IPR001633 EAL domain hmeg3_RS04010 836dfb747892bf017a2719919677ae8b 204 Pfam PF02441 Flavoprotein 16 177 1.4E-23 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 hmeg3_RS04010 836dfb747892bf017a2719919677ae8b 204 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 15 198 37.558 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 hmeg3_RS04010 836dfb747892bf017a2719919677ae8b 204 Gene3D G3DSA:3.40.50.1950 15 204 1.5E-53 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 hmeg3_RS04010 836dfb747892bf017a2719919677ae8b 204 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 16 196 2.6E-74 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 hmeg3_RS04010 836dfb747892bf017a2719919677ae8b 204 SUPERFAMILY SSF52507 16 198 1.83E-62 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 Gene3D G3DSA:3.40.47.10 272 419 6.0E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 SUPERFAMILY SSF53901 14 263 9.51E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 375 3.5E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 SUPERFAMILY SSF53901 231 419 8.37E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 SMART SM00825 Beta-ketoacyl synthase 16 419 6.0E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 258 2.4E-41 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 167 183 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site hmeg3_RS16260 34c5fdbdc576ca5f1a07aa0c4632a972 420 Gene3D G3DSA:3.40.47.10 6 270 7.9E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 2.0E-4 T 28-03-2018 hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 Gene3D G3DSA:3.40.50.720 46 275 4.4E-58 T 28-03-2018 hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 Gene3D G3DSA:3.40.50.720 1 45 6.9E-9 T 28-03-2018 hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 SUPERFAMILY SSF51735 6 274 4.96E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20935 49d486244158a46ae8b61b468fa48fa1 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 273 2.6E-49 T 28-03-2018 hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 SMART SM00267 252 423 3.4E-66 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 261 421 2.1E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Pfam PF00563 EAL domain 439 674 5.2E-70 T 28-03-2018 IPR001633 EAL domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 SMART SM00052 433 679 6.9E-118 T 28-03-2018 IPR001633 EAL domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Gene3D G3DSA:3.30.70.270 264 431 5.1E-63 T 28-03-2018 hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 SUPERFAMILY SSF141868 439 685 3.4E-90 T 28-03-2018 IPR001633 EAL domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 245 6.5E-11 T 28-03-2018 IPR005330 MHYT domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Pfam PF03707 Bacterial signalling protein N terminal repeat 115 167 1.1E-16 T 28-03-2018 IPR005330 MHYT domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Pfam PF03707 Bacterial signalling protein N terminal repeat 52 108 1.8E-22 T 28-03-2018 IPR005330 MHYT domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 418 1.3E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 Gene3D G3DSA:3.20.20.450 432 693 2.0E-100 T 28-03-2018 IPR001633 EAL domain hmeg3_RS17320 1d1eaeb98b34e5981b9d10a8e3c2c3b3 695 SUPERFAMILY SSF55073 268 424 6.28E-52 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS10115 50e9a98e6e64bc1b39f5dd5487906c5e 211 Gene3D G3DSA:3.20.20.70 25 205 1.2E-11 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS10115 50e9a98e6e64bc1b39f5dd5487906c5e 211 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 210 2.6E-105 T 28-03-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 hmeg3_RS10115 50e9a98e6e64bc1b39f5dd5487906c5e 211 SUPERFAMILY SSF102114 46 134 3.01E-6 T 28-03-2018 hmeg3_RS10115 50e9a98e6e64bc1b39f5dd5487906c5e 211 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 211 33.907 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 hmeg3_RS10115 50e9a98e6e64bc1b39f5dd5487906c5e 211 PIRSF PIRSF000370 1 211 3.3E-37 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 hmeg3_RS10115 50e9a98e6e64bc1b39f5dd5487906c5e 211 Pfam PF13394 4Fe-4S single cluster domain 25 122 2.3E-6 T 28-03-2018 hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 SUPERFAMILY SSF56601 240 621 4.17E-87 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 39 624 7.7E-189 T 28-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 Pfam PF00905 Penicillin binding protein transpeptidase domain 312 543 3.1E-13 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 Gene3D G3DSA:1.10.3810.10 46 258 1.6E-49 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 SUPERFAMILY SSF53955 46 219 3.66E-44 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 Gene3D G3DSA:3.40.710.10 259 626 3.9E-79 T 28-03-2018 hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 628 715 7.9E-18 T 28-03-2018 IPR009647 Penicillin-binding, C-terminal hmeg3_RS08950 1193a823d1420bc53f6df957f77538fc 739 Pfam PF00912 Transglycosylase 53 228 4.8E-46 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS17375 a032d973a614bb19c0c4181ebfb8b5a6 469 Gene3D G3DSA:3.40.190.10 110 219 4.6E-9 T 28-03-2018 hmeg3_RS17375 a032d973a614bb19c0c4181ebfb8b5a6 469 Pfam PF13379 NMT1-like family 110 348 7.4E-79 T 28-03-2018 hmeg3_RS17375 a032d973a614bb19c0c4181ebfb8b5a6 469 Gene3D G3DSA:3.40.190.10 220 423 7.2E-38 T 28-03-2018 hmeg3_RS17375 a032d973a614bb19c0c4181ebfb8b5a6 469 SUPERFAMILY SSF53850 112 334 2.76E-38 T 28-03-2018 hmeg3_RS23735 6753230403622fd3d4d2350fc91a3da4 228 Pfam PF13410 Glutathione S-transferase, C-terminal domain 138 201 8.4E-8 T 28-03-2018 hmeg3_RS23735 6753230403622fd3d4d2350fc91a3da4 228 SUPERFAMILY SSF52833 1 91 3.28E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS23735 6753230403622fd3d4d2350fc91a3da4 228 Gene3D G3DSA:1.20.1050.10 98 213 9.5E-19 T 28-03-2018 hmeg3_RS23735 6753230403622fd3d4d2350fc91a3da4 228 Gene3D G3DSA:3.40.30.10 1 97 7.5E-21 T 28-03-2018 hmeg3_RS23735 6753230403622fd3d4d2350fc91a3da4 228 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 82 6.3E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS23735 6753230403622fd3d4d2350fc91a3da4 228 SUPERFAMILY SSF47616 84 212 1.18E-19 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS02920 6cc0988e30ab393009e99942bdb4f9f9 232 Pfam PF00583 Acetyltransferase (GNAT) family 93 170 8.9E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS02920 6cc0988e30ab393009e99942bdb4f9f9 232 SUPERFAMILY SSF55729 39 175 4.33E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS02920 6cc0988e30ab393009e99942bdb4f9f9 232 Gene3D G3DSA:3.40.630.30 19 211 3.3E-14 T 28-03-2018 hmeg3_RS03520 48dac279d9f01825e0786e126c1dc5b2 114 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 95 6.7E-29 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 hmeg3_RS03520 48dac279d9f01825e0786e126c1dc5b2 114 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 98 6.9E-15 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 hmeg3_RS03520 48dac279d9f01825e0786e126c1dc5b2 114 Gene3D G3DSA:1.10.287.1080 1 100 5.8E-22 T 28-03-2018 hmeg3_RS03520 48dac279d9f01825e0786e126c1dc5b2 114 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 95 21.815 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 hmeg3_RS03520 48dac279d9f01825e0786e126c1dc5b2 114 SUPERFAMILY SSF101386 4 99 1.53E-22 T 28-03-2018 hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 SUPERFAMILY SSF50249 191 296 3.71E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 Gene3D G3DSA:3.30.1490.70 153 206 3.8E-12 T 28-03-2018 hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 Pfam PF14743 DNA ligase OB-like domain 231 296 2.9E-30 T 28-03-2018 IPR029319 DNA ligase, OB-like domain hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 SUPERFAMILY SSF56091 47 217 7.38E-40 T 28-03-2018 hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 Pfam PF01068 ATP dependent DNA ligase domain 101 217 5.0E-8 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 Gene3D G3DSA:3.30.470.30 39 152 5.1E-16 T 28-03-2018 hmeg3_RS14110 ec0adb9edd8ae099d0c16dfcd6acd5b7 298 Gene3D G3DSA:2.40.50.140 207 298 1.1E-21 T 28-03-2018 hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 110 127 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 SUPERFAMILY SSF51230 79 153 1.2E-24 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 83 96 7.4E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 115 128 7.4E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 114 7.4E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 Gene3D G3DSA:2.40.50.100 4 154 5.9E-20 T 28-03-2018 hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 Pfam PF00364 Biotin-requiring enzyme 81 153 1.5E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment hmeg3_RS21755 602a8e330c7ebb7a85cf0543c8f7fac8 154 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 5.5E-56 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 hmeg3_RS16650 86e7115a4ae6af16cff7ad279af325ee 352 SUPERFAMILY SSF51445 18 311 2.63E-75 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS16650 86e7115a4ae6af16cff7ad279af325ee 352 Gene3D G3DSA:3.20.20.300 17 329 1.1E-71 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 hmeg3_RS16650 86e7115a4ae6af16cff7ad279af325ee 352 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 23 313 3.4E-70 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 hmeg3_RS16650 86e7115a4ae6af16cff7ad279af325ee 352 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 250 267 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 hmeg3_RS16650 86e7115a4ae6af16cff7ad279af325ee 352 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 19 352 49.519 T 28-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 Gene3D G3DSA:3.40.50.970 373 549 3.0E-35 T 28-03-2018 hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 SUPERFAMILY SSF52518 371 548 1.47E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 192 5.5E-41 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 SUPERFAMILY SSF52467 206 360 4.36E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 SUPERFAMILY SSF52518 26 198 3.13E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 Gene3D G3DSA:3.40.50.970 19 205 4.6E-35 T 28-03-2018 hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 401 546 2.6E-28 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 Gene3D G3DSA:3.40.50.1220 206 372 1.7E-21 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 211 339 1.2E-16 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 hmeg3_RS23605 346106a71c17f564c195f928893edbb7 549 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Gene3D G3DSA:1.25.40.10 186 213 6.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Gene3D G3DSA:1.25.40.10 214 343 5.7E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SUPERFAMILY SSF48452 12 264 1.14E-32 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SMART SM00028 171 204 48.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SMART SM00028 103 136 0.73 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SMART SM00028 137 170 0.044 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SMART SM00028 35 68 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SMART SM00028 205 238 0.0012 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SMART SM00028 69 102 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Pfam PF13432 Tetratricopeptide repeat 73 136 1.3E-5 T 28-03-2018 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Pfam PF13432 Tetratricopeptide repeat 141 204 0.0024 T 28-03-2018 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Pfam PF13432 Tetratricopeptide repeat 7 68 0.0024 T 28-03-2018 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Gene3D G3DSA:1.25.40.10 85 132 1.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Gene3D G3DSA:1.25.40.10 133 185 1.1E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Gene3D G3DSA:3.40.50.2000 391 558 8.3E-32 T 28-03-2018 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 SUPERFAMILY SSF53756 291 549 8.89E-19 T 28-03-2018 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 472 503 8.0E-5 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 hmeg3_RS15005 10913c493de72d6e3968cb6d1f77e58b 558 Gene3D G3DSA:1.25.40.10 1 84 2.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS13050 17929134e1c8564798757bae63cd9ec7 365 SMART SM00220 28 333 6.8E-9 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 hmeg3_RS13050 17929134e1c8564798757bae63cd9ec7 365 Pfam PF00069 Protein kinase domain 35 320 3.8E-12 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 hmeg3_RS13050 17929134e1c8564798757bae63cd9ec7 365 SUPERFAMILY SSF56112 23 325 2.02E-22 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS13050 17929134e1c8564798757bae63cd9ec7 365 Gene3D G3DSA:3.30.200.20 18 129 2.8E-6 T 28-03-2018 hmeg3_RS13050 17929134e1c8564798757bae63cd9ec7 365 Gene3D G3DSA:1.10.510.10 130 333 1.1E-13 T 28-03-2018 hmeg3_RS10315 5f8a21bd552dc98b96cd751f07f9383b 355 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 255 331 2.1E-4 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 hmeg3_RS10315 5f8a21bd552dc98b96cd751f07f9383b 355 SUPERFAMILY SSF103025 41 271 6.12E-61 T 28-03-2018 hmeg3_RS10315 5f8a21bd552dc98b96cd751f07f9383b 355 Pfam PF01571 Aminomethyltransferase folate-binding domain 50 236 1.9E-12 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal hmeg3_RS10315 5f8a21bd552dc98b96cd751f07f9383b 355 Gene3D G3DSA:3.30.70.1400 52 268 1.9E-25 T 28-03-2018 hmeg3_RS10315 5f8a21bd552dc98b96cd751f07f9383b 355 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 216 278 3.6E-25 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site hmeg3_RS10315 5f8a21bd552dc98b96cd751f07f9383b 355 PIRSF PIRSF006487 6 355 6.2E-13 T 28-03-2018 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 Gene3D G3DSA:3.20.20.70 1 331 4.0E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 8.5E-178 T 28-03-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 SUPERFAMILY SSF51569 3 329 3.08E-103 T 28-03-2018 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 1.2E-97 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 PIRSF PIRSF001359 1 329 2.1E-82 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 hmeg3_RS20075 f1bf67ed67070327d9ab2a3e70028ba4 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 328 8.5E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 hmeg3_RS24590 3a16e539c7f25b40c5773c1c23b5a9e8 443 Pfam PF07690 Major Facilitator Superfamily 37 399 6.5E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS24590 3a16e539c7f25b40c5773c1c23b5a9e8 443 SUPERFAMILY SSF103473 26 435 2.09E-86 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS24590 3a16e539c7f25b40c5773c1c23b5a9e8 443 Gene3D G3DSA:1.20.1250.20 20 229 8.6E-36 T 28-03-2018 hmeg3_RS24590 3a16e539c7f25b40c5773c1c23b5a9e8 443 Gene3D G3DSA:1.20.1250.20 248 443 4.5E-29 T 28-03-2018 hmeg3_RS21890 75d9c5267ca980444f2b8f74554b3877 329 Pfam PF00348 Polyprenyl synthetase 38 273 3.4E-78 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 hmeg3_RS21890 75d9c5267ca980444f2b8f74554b3877 329 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site hmeg3_RS21890 75d9c5267ca980444f2b8f74554b3877 329 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 88 102 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site hmeg3_RS21890 75d9c5267ca980444f2b8f74554b3877 329 Gene3D G3DSA:1.10.600.10 2 329 1.1E-105 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS21890 75d9c5267ca980444f2b8f74554b3877 329 SUPERFAMILY SSF48576 11 328 1.23E-101 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS21150 0a3e10c5ed4a58052b5c04cbb50c0f88 343 Gene3D G3DSA:3.40.50.2000 1 168 1.0E-39 T 28-03-2018 hmeg3_RS21150 0a3e10c5ed4a58052b5c04cbb50c0f88 343 SUPERFAMILY SSF53756 2 323 3.92E-66 T 28-03-2018 hmeg3_RS21150 0a3e10c5ed4a58052b5c04cbb50c0f88 343 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 306 1.5E-42 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 hmeg3_RS21150 0a3e10c5ed4a58052b5c04cbb50c0f88 343 Gene3D G3DSA:3.40.50.2000 170 328 1.1E-24 T 28-03-2018 hmeg3_RS21150 0a3e10c5ed4a58052b5c04cbb50c0f88 343 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 322 3.1E-102 T 28-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 SUPERFAMILY SSF53335 3 257 7.97E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 Gene3D G3DSA:3.40.50.150 1 203 3.8E-50 T 28-03-2018 hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 Gene3D G3DSA:1.10.8.100 204 261 2.4E-20 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 3 256 53.564 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 SMART SM00650 19 191 3.8E-75 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 Pfam PF00398 Ribosomal RNA adenine dimethylase 5 256 7.6E-60 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 35 62 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 hmeg3_RS19895 20a222354d6ddfb830684de680b7ffa2 261 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 254 3.6E-78 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 416 3.8E-69 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 Pfam PF07690 Major Facilitator Superfamily 18 404 3.9E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 Gene3D G3DSA:1.20.1250.20 258 466 8.5E-17 T 28-03-2018 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 Gene3D G3DSA:1.20.1250.20 5 199 8.7E-30 T 28-03-2018 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 SUPERFAMILY SSF103473 8 196 4.84E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 SUPERFAMILY SSF103473 247 462 4.84E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 162 186 6.7E-5 T 28-03-2018 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 6.7E-5 T 28-03-2018 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 6.7E-5 T 28-03-2018 hmeg3_RS04415 e708119c10c252d2c798408dc9b4d2ac 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 6.7E-5 T 28-03-2018 hmeg3_RS07700 28747dfe7fd6abe5ab3be33db68fbe4f 116 SUPERFAMILY SSF55298 12 115 1.88E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS07700 28747dfe7fd6abe5ab3be33db68fbe4f 116 Pfam PF01042 Endoribonuclease L-PSP 7 114 1.6E-25 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS07700 28747dfe7fd6abe5ab3be33db68fbe4f 116 Gene3D G3DSA:3.30.1330.40 2 116 5.5E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS07700 28747dfe7fd6abe5ab3be33db68fbe4f 116 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 91 109 - T 28-03-2018 IPR019897 RidA, conserved site hmeg3_RS11060 b393d481f395071cafce96b6c7ffb6d5 299 Pfam PF12146 Serine aminopeptidase, S33 19 255 4.7E-15 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS11060 b393d481f395071cafce96b6c7ffb6d5 299 PIRSF PIRSF017388 6 143 1.9E-17 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 hmeg3_RS11060 b393d481f395071cafce96b6c7ffb6d5 299 PIRSF PIRSF017388 159 272 1.5E-15 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 hmeg3_RS11060 b393d481f395071cafce96b6c7ffb6d5 299 Gene3D G3DSA:3.40.50.1820 3 273 4.9E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11060 b393d481f395071cafce96b6c7ffb6d5 299 SUPERFAMILY SSF53474 22 270 2.11E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00020 abc324a880142ebc24ea9919658c49e5 505 Gene3D G3DSA:3.40.309.10 274 472 5.3E-47 T 28-03-2018 hmeg3_RS00020 abc324a880142ebc24ea9919658c49e5 505 SUPERFAMILY SSF53720 17 492 5.37E-125 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00020 abc324a880142ebc24ea9919658c49e5 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00020 abc324a880142ebc24ea9919658c49e5 505 Pfam PF00171 Aldehyde dehydrogenase family 17 483 1.8E-121 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00020 abc324a880142ebc24ea9919658c49e5 505 Gene3D G3DSA:3.40.605.10 11 273 1.0E-71 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Pfam PF04607 Region found in RelA / SpoT proteins 256 365 7.9E-38 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Gene3D G3DSA:3.10.20.30 414 485 7.1E-21 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 SMART SM00954 256 366 3.0E-65 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Gene3D G3DSA:3.30.460.10 213 346 8.5E-43 T 28-03-2018 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 56 750 1.4E-180 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 SUPERFAMILY SSF55021 675 751 1.12E-13 T 28-03-2018 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Pfam PF02824 TGS domain 419 478 9.9E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 SUPERFAMILY SSF81271 406 478 2.4E-19 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Gene3D G3DSA:3.30.70.260 675 752 1.7E-8 T 28-03-2018 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Pfam PF13291 ACT domain 675 751 4.3E-13 T 28-03-2018 IPR002912 ACT domain hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 SUPERFAMILY SSF109604 17 211 5.65E-41 T 28-03-2018 hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 Pfam PF13328 HD domain 30 197 5.2E-44 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS07705 a74ff6f2c5dc917121cc1c2a191c9a1c 752 SUPERFAMILY SSF81301 213 388 3.92E-64 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 SUPERFAMILY SSF49503 184 326 6.69E-52 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 SUPERFAMILY SSF49503 127 154 6.69E-52 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 39 120 1.4E-14 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 SUPERFAMILY SSF46626 282 379 2.58E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 109 129 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 226 243 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 244 261 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 182 203 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 206 226 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 97 109 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 PRINTS PR01166 Cytochrome c oxidase subunit II signature 131 150 1.6E-37 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 SUPERFAMILY SSF81464 36 129 1.08E-27 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 Gene3D G3DSA:1.10.760.10 304 390 9.9E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 Gene3D G3DSA:1.10.287.90 37 126 4.7E-28 T 28-03-2018 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 207 255 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 135 262 2.0E-37 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 Gene3D G3DSA:2.60.40.420 127 303 2.1E-50 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 296 366 7.7E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03285 e015770f7a0ec6e149f16920818abb61 390 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 48 271 1.6E-58 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS15075 4388a447d12c37702597795535835f68 318 Pfam PF00583 Acetyltransferase (GNAT) family 192 296 5.9E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS15075 4388a447d12c37702597795535835f68 318 SUPERFAMILY SSF46785 12 146 2.24E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15075 4388a447d12c37702597795535835f68 318 Gene3D G3DSA:1.10.10.10 2 164 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15075 4388a447d12c37702597795535835f68 318 SMART SM00347 32 132 1.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15075 4388a447d12c37702597795535835f68 318 SUPERFAMILY SSF55729 186 308 7.72E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS15075 4388a447d12c37702597795535835f68 318 Pfam PF12802 MarR family 40 95 3.1E-11 T 28-03-2018 hmeg3_RS15075 4388a447d12c37702597795535835f68 318 Gene3D G3DSA:3.40.630.30 173 315 1.6E-22 T 28-03-2018 hmeg3_RS22575 aa0ab8bb6933f51524e423f0aab42d21 475 Gene3D G3DSA:3.30.420.10 5 106 1.1E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS22575 aa0ab8bb6933f51524e423f0aab42d21 475 Pfam PF01551 Peptidase family M23 375 468 9.3E-27 T 28-03-2018 IPR016047 Peptidase M23 hmeg3_RS22575 aa0ab8bb6933f51524e423f0aab42d21 475 SUPERFAMILY SSF51261 269 471 2.51E-43 T 28-03-2018 IPR011055 Duplicated hybrid motif hmeg3_RS22575 aa0ab8bb6933f51524e423f0aab42d21 475 Gene3D G3DSA:2.70.70.10 266 475 9.3E-39 T 28-03-2018 hmeg3_RS09855 6f8eecb0802f34e66af634e2a0c5974b 120 Pfam PF03960 ArsC family 8 117 5.6E-11 T 28-03-2018 IPR006660 Arsenate reductase-like hmeg3_RS09855 6f8eecb0802f34e66af634e2a0c5974b 120 Gene3D G3DSA:3.40.30.10 4 119 2.4E-32 T 28-03-2018 hmeg3_RS09855 6f8eecb0802f34e66af634e2a0c5974b 120 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 6 117 3.4E-28 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR hmeg3_RS09855 6f8eecb0802f34e66af634e2a0c5974b 120 SUPERFAMILY SSF52833 5 118 4.98E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00184 Neisseria sp. porin signature 59 84 2.5E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00184 Neisseria sp. porin signature 324 348 2.5E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00184 Neisseria sp. porin signature 161 178 2.5E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 SUPERFAMILY SSF56935 21 386 1.26E-74 T 28-03-2018 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 190 202 1.5E-9 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 162 173 1.5E-9 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 327 344 1.5E-9 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 104 114 1.5E-9 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 57 68 1.5E-9 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 Pfam PF13609 Gram-negative porin 7 352 8.2E-54 T 28-03-2018 hmeg3_RS02230 63e5219ffe9919c2bc445a67ec9f8d66 386 Gene3D G3DSA:2.40.160.10 9 386 2.0E-73 T 28-03-2018 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 Pfam PF08281 Sigma-70, region 4 114 162 4.3E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 SUPERFAMILY SSF88946 10 90 2.47E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 SUPERFAMILY SSF88659 86 165 4.3E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 Gene3D G3DSA:1.10.1740.10 1 75 3.2E-14 T 28-03-2018 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 Gene3D G3DSA:3.10.450.50 157 294 1.0E-8 T 28-03-2018 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 Gene3D G3DSA:1.10.10.10 76 156 1.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 164 1.0E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12095 931d12d6bc24f54962436e574055bc41 313 Pfam PF04542 Sigma-70 region 2 12 77 5.9E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS17555 be89fbb184b12a7946020331b9f2b36c 309 SUPERFAMILY SSF51430 2 289 1.96E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS17555 be89fbb184b12a7946020331b9f2b36c 309 Gene3D G3DSA:3.20.20.100 1 307 1.1E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS17555 be89fbb184b12a7946020331b9f2b36c 309 Pfam PF00248 Aldo/keto reductase family 9 288 7.6E-77 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 Gene3D G3DSA:2.40.30.10 15 100 9.8E-17 T 28-03-2018 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 58 65 4.7E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 229 237 4.7E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 118 137 4.7E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 Pfam PF00175 Oxidoreductase NAD-binding domain 119 243 3.0E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 Gene3D G3DSA:3.40.50.80 105 268 1.2E-21 T 28-03-2018 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 Pfam PF00970 Oxidoreductase FAD-binding domain 25 97 3.0E-8 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 SUPERFAMILY SSF63380 13 106 8.96E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS15915 1c2e668979631e973079879ee47a13cd 268 SUPERFAMILY SSF52343 111 254 1.83E-29 T 28-03-2018 hmeg3_RS20920 52f4669c747967952d3c82a70a35939e 296 Gene3D G3DSA:3.20.20.60 1 290 7.3E-84 T 28-03-2018 hmeg3_RS20920 52f4669c747967952d3c82a70a35939e 296 Pfam PF13714 Phosphoenolpyruvate phosphomutase 9 248 1.5E-54 T 28-03-2018 hmeg3_RS20920 52f4669c747967952d3c82a70a35939e 296 SUPERFAMILY SSF51621 6 281 2.06E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS20645 c9e2a94e1e93afa66d8a4e1883f0cdea 228 Gene3D G3DSA:1.10.10.10 1 65 9.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20645 c9e2a94e1e93afa66d8a4e1883f0cdea 228 Pfam PF13280 WYL domain 137 221 1.3E-14 T 28-03-2018 IPR026881 WYL domain hmeg3_RS20645 c9e2a94e1e93afa66d8a4e1883f0cdea 228 SUPERFAMILY SSF46785 1 60 2.99E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20645 c9e2a94e1e93afa66d8a4e1883f0cdea 228 Pfam PF08279 HTH domain 6 59 8.0E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 hmeg3_RS01985 2e23bf66c3e0a27b114757b61c621821 336 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 332 1.3E-137 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 hmeg3_RS01985 2e23bf66c3e0a27b114757b61c621821 336 SUPERFAMILY SSF51735 1 333 5.0E-99 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01985 2e23bf66c3e0a27b114757b61c621821 336 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 322 5.1E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01985 2e23bf66c3e0a27b114757b61c621821 336 Gene3D G3DSA:3.90.25.10 207 251 1.2E-9 T 28-03-2018 hmeg3_RS01985 2e23bf66c3e0a27b114757b61c621821 336 Gene3D G3DSA:3.90.25.10 252 335 3.3E-23 T 28-03-2018 hmeg3_RS01985 2e23bf66c3e0a27b114757b61c621821 336 Gene3D G3DSA:3.40.50.720 1 206 1.2E-45 T 28-03-2018 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 SUPERFAMILY SSF47413 1 77 2.5E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 Pfam PF02560 Cyanate lyase C-terminal domain 80 145 4.3E-35 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 TIGRFAM TIGR00673 cynS: cyanase 4 147 3.3E-50 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 Gene3D G3DSA:1.10.260.40 1 80 1.7E-6 T 28-03-2018 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 PIRSF PIRSF001263 1 147 1.4E-49 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 SUPERFAMILY SSF55234 80 147 3.92E-30 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 SMART SM01116 75 147 7.5E-49 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 79.637 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 Gene3D G3DSA:3.30.1160.10 81 146 5.6E-37 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 PRINTS PR01693 Cyanase signature 14 29 2.5E-26 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 PRINTS PR01693 Cyanase signature 34 51 2.5E-26 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 PRINTS PR01693 Cyanase signature 132 142 2.5E-26 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 PRINTS PR01693 Cyanase signature 83 97 2.5E-26 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS17360 aa1cc1281a167eb0d5ee5048d699737d 147 PRINTS PR01693 Cyanase signature 101 117 2.5E-26 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS20840 d51f633ae276851ba9908056b531afad 135 Gene3D G3DSA:3.30.160.20 4 135 1.2E-37 T 28-03-2018 hmeg3_RS20840 d51f633ae276851ba9908056b531afad 135 Pfam PF00472 RF-1 domain 7 130 5.0E-22 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 hmeg3_RS20840 d51f633ae276851ba9908056b531afad 135 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 19 35 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 hmeg3_RS20840 d51f633ae276851ba9908056b531afad 135 SUPERFAMILY SSF75620 7 98 4.32E-11 T 28-03-2018 hmeg3_RS21510 e4e859960c1d5eb53db9c783b03cc8e6 322 SUPERFAMILY SSF100950 63 319 3.89E-57 T 28-03-2018 hmeg3_RS21510 e4e859960c1d5eb53db9c783b03cc8e6 322 Gene3D G3DSA:3.40.50.1360 54 320 8.6E-32 T 28-03-2018 hmeg3_RS21510 e4e859960c1d5eb53db9c783b03cc8e6 322 Pfam PF04198 Putative sugar-binding domain 58 318 5.7E-63 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 hmeg3_RS21510 e4e859960c1d5eb53db9c783b03cc8e6 322 Gene3D G3DSA:1.10.10.60 1 53 1.9E-12 T 28-03-2018 hmeg3_RS02835 704059630811a6a902db1b77af9a29ea 191 SUPERFAMILY SSF46785 28 150 5.96E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02835 704059630811a6a902db1b77af9a29ea 191 Pfam PF01475 Ferric uptake regulator family 32 107 2.1E-6 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 hmeg3_RS02835 704059630811a6a902db1b77af9a29ea 191 Gene3D G3DSA:1.10.10.10 25 112 3.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 50.405 T 28-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 Gene3D G3DSA:3.30.9.10 148 214 1.0E-9 T 28-03-2018 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 Gene3D G3DSA:3.40.50.720 1 147 5.3E-8 T 28-03-2018 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 SUPERFAMILY SSF54373 269 359 1.57E-18 T 28-03-2018 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 Pfam PF01266 FAD dependent oxidoreductase 2 397 1.6E-72 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 SUPERFAMILY SSF51905 107 271 9.45E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 SUPERFAMILY SSF51905 1 54 9.45E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 SUPERFAMILY SSF51905 359 416 9.45E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14200 eb0e80ebd02ad5838b0d8b97a0d677b6 427 Gene3D G3DSA:3.30.9.10 215 358 1.5E-22 T 28-03-2018 hmeg3_RS14970 5ee009696b2683d7c9b7d7ff6bee4d81 469 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 80 120 2.1E-9 T 28-03-2018 IPR011964 YVTN beta-propeller repeat hmeg3_RS14970 5ee009696b2683d7c9b7d7ff6bee4d81 469 SUPERFAMILY SSF50974 6 335 8.11E-58 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 hmeg3_RS14970 5ee009696b2683d7c9b7d7ff6bee4d81 469 Gene3D G3DSA:2.130.10.10 15 67 0.0016 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS14970 5ee009696b2683d7c9b7d7ff6bee4d81 469 Gene3D G3DSA:2.130.10.10 204 378 4.1E-18 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS14970 5ee009696b2683d7c9b7d7ff6bee4d81 469 Gene3D G3DSA:2.130.10.10 68 203 4.0E-28 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS21015 40be2f798a5c433c75bf47701a4925a6 428 SMART SM00382 107 294 2.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21015 40be2f798a5c433c75bf47701a4925a6 428 Pfam PF00005 ABC transporter 98 246 4.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21015 40be2f798a5c433c75bf47701a4925a6 428 Gene3D G3DSA:3.40.50.300 75 326 3.9E-76 T 28-03-2018 hmeg3_RS21015 40be2f798a5c433c75bf47701a4925a6 428 SUPERFAMILY SSF52540 80 316 1.69E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21015 40be2f798a5c433c75bf47701a4925a6 428 Gene3D G3DSA:3.30.70.260 327 408 1.6E-10 T 28-03-2018 hmeg3_RS21015 40be2f798a5c433c75bf47701a4925a6 428 ProSitePatterns PS00211 ABC transporters family signature. 218 232 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF55008 8 76 3.8E-20 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 ProSitePatterns PS01047 Heavy-metal-associated domain. 84 113 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Gene3D G3DSA:3.30.70.100 10 77 1.6E-20 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 223 810 5.5E-189 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 727 2.0E-24 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 507 2.0E-24 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 343 357 2.0E-24 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 731 743 2.0E-24 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 659 2.0E-24 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Pfam PF00702 haloacid dehalogenase-like hydrolase 490 722 9.8E-37 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Gene3D G3DSA:3.40.50.1000 630 779 1.9E-41 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 ProSitePatterns PS01229 Hypothetical cof family signature 2. 708 730 - T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF81665 394 487 2.22E-17 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF81665 757 786 2.22E-17 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF81665 240 297 2.22E-17 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 14 75 1.2E-9 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 80 142 2.1E-12 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 495 501 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 205 811 2.2E-169 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 46 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF56784 491 511 3.57E-56 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF56784 549 808 3.57E-56 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Gene3D G3DSA:1.20.1110.10 260 507 2.5E-43 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF81653 296 393 3.66E-26 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Pfam PF00403 Heavy-metal-associated domain 14 74 1.1E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Pfam PF00403 Heavy-metal-associated domain 81 140 8.2E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 624 791 1.9E-38 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 266 514 4.0E-43 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Gene3D G3DSA:3.30.70.100 78 146 2.8E-22 T 28-03-2018 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Gene3D G3DSA:3.40.1110.10 508 629 2.3E-25 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 SUPERFAMILY SSF55008 78 145 1.15E-20 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00941 Cadmium-transporting ATPase signature 359 375 1.4E-9 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00941 Cadmium-transporting ATPase signature 298 314 1.4E-9 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00941 Cadmium-transporting ATPase signature 15 24 1.4E-9 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00941 Cadmium-transporting ATPase signature 93 114 1.4E-9 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 PRINTS PR00941 Cadmium-transporting ATPase signature 378 392 1.4E-9 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 hmeg3_RS14670 691c8940fdfcf001330a76170e666d4a 831 Pfam PF00122 E1-E2 ATPase 294 472 2.6E-54 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 Gene3D G3DSA:1.20.1250.20 16 212 4.3E-24 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 416 435 4.7E-7 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 176 200 4.7E-7 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 4.7E-7 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 4.7E-7 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 SUPERFAMILY SSF103473 12 206 4.32E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 SUPERFAMILY SSF103473 264 435 4.32E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 SUPERFAMILY SSF103473 494 521 4.32E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 Pfam PF07690 Major Facilitator Superfamily 32 425 5.4E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 Gene3D G3DSA:1.20.1250.20 275 532 8.4E-28 T 28-03-2018 hmeg3_RS00930 343a8d469797795614cdbcbf196c63d8 532 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 517 6.3E-120 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 465 1.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 SMART SM00304 204 256 1.3E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 Pfam PF00672 HAMP domain 205 253 2.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 Gene3D G3DSA:1.10.287.130 247 319 1.4E-6 T 28-03-2018 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 SMART SM00387 354 466 4.0E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 SUPERFAMILY SSF55874 316 464 1.31E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 Gene3D G3DSA:3.30.565.10 320 467 4.0E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 9.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 9.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 9.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15985 1903722b5e36063c5e8ff2fe3caf8f07 484 SUPERFAMILY SSF47384 241 311 1.41E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 221 228 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 Pfam PF00171 Aldehyde dehydrogenase family 20 449 1.8E-79 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 Gene3D G3DSA:3.40.605.10 3 240 1.2E-53 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 249 260 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 Gene3D G3DSA:3.40.309.10 241 430 1.5E-54 T 28-03-2018 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 SUPERFAMILY SSF53720 14 452 9.56E-104 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS09075 7be3d6cfd498d6ba016144728e612bfa 479 PIRSF PIRSF036492 1 479 3.8E-149 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 hmeg3_RS17290 9a76c6e8dfcf3f6c2c5c40b85f5ee14d 434 Pfam PF03631 Virulence factor BrkB 22 268 1.2E-56 T 28-03-2018 IPR017039 Virulence factor BrkB hmeg3_RS17290 9a76c6e8dfcf3f6c2c5c40b85f5ee14d 434 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 268 1.1E-69 T 28-03-2018 IPR017039 Virulence factor BrkB hmeg3_RS17290 9a76c6e8dfcf3f6c2c5c40b85f5ee14d 434 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 9 299 22.875 T 28-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 SMART SM00304 245 297 8.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 475 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 461 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 Gene3D G3DSA:1.10.287.130 288 361 3.9E-12 T 28-03-2018 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 SUPERFAMILY SSF47384 281 361 2.75E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 SUPERFAMILY SSF55874 355 519 1.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 SMART SM00387 410 522 1.8E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 Gene3D G3DSA:3.30.565.10 362 522 3.3E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 SMART SM00388 298 366 2.3E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 411 521 1.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS00225 3c4df325199ef1d1a247d09f7435bab5 522 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 360 2.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 308 4.2E-91 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 Pfam PF00551 Formyl transferase 3 188 5.7E-42 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 SUPERFAMILY SSF50486 212 313 1.57E-30 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 312 36.3 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 SUPERFAMILY SSF53328 1 214 4.97E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 Gene3D G3DSA:3.40.50.170 1 213 5.8E-70 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 140 163 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 Gene3D G3DSA:3.10.25.10 214 316 6.5E-32 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS02515 85b3d9b863d117af5563df05cbf8aac2 317 Pfam PF02911 Formyl transferase, C-terminal domain 211 309 1.5E-27 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 PIRSF PIRSF036389 5 766 1.9E-256 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Gene3D G3DSA:3.30.365.10 348 442 2.6E-30 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Gene3D G3DSA:3.30.365.10 618 765 8.7E-37 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Gene3D G3DSA:3.90.1170.50 199 347 1.5E-32 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Gene3D G3DSA:3.30.365.10 27 198 7.0E-39 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 SUPERFAMILY SSF56003 332 760 1.83E-111 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 332 611 3.2E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 26 195 1.5E-15 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 628 707 4.1E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 Gene3D G3DSA:3.30.365.10 443 617 6.2E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 SUPERFAMILY SSF56003 25 254 7.67E-44 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS12630 d2a20988443527c177c92a3c6480fcaa 769 SMART SM01008 221 310 3.6E-27 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS00855 3cef24d983369d816542c51f04a44d0a 301 Pfam PF00753 Metallo-beta-lactamase superfamily 50 236 2.1E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00855 3cef24d983369d816542c51f04a44d0a 301 SUPERFAMILY SSF56281 36 260 2.66E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00855 3cef24d983369d816542c51f04a44d0a 301 SMART SM00849 51 236 3.4E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00855 3cef24d983369d816542c51f04a44d0a 301 Gene3D G3DSA:3.60.15.10 23 265 2.8E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 SMART SM00487 35 240 7.0E-61 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 Gene3D G3DSA:3.40.50.300 3 240 2.6E-63 T 28-03-2018 hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 Pfam PF00271 Helicase conserved C-terminal domain 252 357 2.3E-28 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 SUPERFAMILY SSF52540 92 378 7.71E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 SMART SM00490 276 357 1.1E-32 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 171 179 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 Pfam PF00270 DEAD/DEAH box helicase 40 214 7.1E-52 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS18950 067aa768c7b7cd80870a3962e701e77b 503 Gene3D G3DSA:3.40.50.300 241 390 1.5E-47 T 28-03-2018 hmeg3_RS18935 742affbf79cfbed686a24a3b0042d063 191 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 hmeg3_RS18935 742affbf79cfbed686a24a3b0042d063 191 Pfam PF03358 NADPH-dependent FMN reductase 13 131 9.0E-11 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS18935 742affbf79cfbed686a24a3b0042d063 191 SUPERFAMILY SSF52218 1 190 3.67E-50 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS18935 742affbf79cfbed686a24a3b0042d063 191 Gene3D G3DSA:3.40.50.360 1 191 2.5E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 4.4E-104 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.7E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 SMART SM01130 1 289 1.5E-146 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 SUPERFAMILY SSF51569 2 288 1.47E-105 T 28-03-2018 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 Gene3D G3DSA:3.20.20.70 1 292 8.0E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 PIRSF PIRSF001365 1 292 3.8E-96 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 286 2.3E-111 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 67.022 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS17135 54dd31277c9269cd86e95de309720f91 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 hmeg3_RS02125 c7ff77cea2f221c461d60a35aff7da22 323 Pfam PF05275 Copper resistance protein B precursor (CopB) 117 323 1.4E-83 T 28-03-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 hmeg3_RS02125 c7ff77cea2f221c461d60a35aff7da22 323 Gene3D G3DSA:2.60.40.420 23 312 9.3E-5 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS04710 c5035ba62fb481ae5a7d1513687fc34d 142 Pfam PF00572 Ribosomal protein L13 14 138 2.7E-53 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS04710 c5035ba62fb481ae5a7d1513687fc34d 142 PIRSF PIRSF002181 1 141 9.6E-46 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS04710 c5035ba62fb481ae5a7d1513687fc34d 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 26.481 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS04710 c5035ba62fb481ae5a7d1513687fc34d 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 3.8E-60 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS04710 c5035ba62fb481ae5a7d1513687fc34d 142 SUPERFAMILY SSF52161 1 139 3.14E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS04710 c5035ba62fb481ae5a7d1513687fc34d 142 Gene3D G3DSA:3.90.1180.10 1 142 4.9E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS17530 63d67bf688481cb0a3d232f1732ac594 299 Gene3D G3DSA:1.10.3720.10 63 295 2.8E-39 T 28-03-2018 hmeg3_RS17530 63d67bf688481cb0a3d232f1732ac594 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 286 2.2E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17530 63d67bf688481cb0a3d232f1732ac594 299 SUPERFAMILY SSF161098 54 281 1.96E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17530 63d67bf688481cb0a3d232f1732ac594 299 Gene3D G3DSA:1.20.58.370 1 43 2.6E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain hmeg3_RS16495 122c032b9e6e10566793a9abec0d1245 354 SUPERFAMILY SSF74650 3 350 2.89E-110 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS16495 122c032b9e6e10566793a9abec0d1245 354 PIRSF PIRSF005096 1 353 8.8E-121 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 hmeg3_RS16495 122c032b9e6e10566793a9abec0d1245 354 Gene3D G3DSA:2.70.98.10 4 354 1.1E-115 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 hmeg3_RS16495 122c032b9e6e10566793a9abec0d1245 354 Pfam PF01263 Aldose 1-epimerase 17 349 1.9E-88 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 207 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 SUPERFAMILY SSF51735 2 183 9.29E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 181 2.3E-49 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 258 3.2E-16 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 Gene3D G3DSA:3.40.50.720 1 183 1.1E-42 T 28-03-2018 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 SUPERFAMILY SSF48179 186 263 8.5E-15 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 Gene3D G3DSA:1.10.1040.10 186 280 1.1E-18 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS17675 63c29d0e7cead5b7b111d7d353215105 310 PIRSF PIRSF000105 1 286 3.8E-69 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 Gene3D G3DSA:3.30.499.10 325 470 6.2E-51 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 Gene3D G3DSA:3.40.1060.10 156 289 1.6E-31 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 466 8.2E-188 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 Gene3D G3DSA:3.30.499.10 1 155 3.2E-33 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 Pfam PF00330 Aconitase family (aconitate hydratase) 8 458 2.7E-135 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 196 209 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 210 223 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 120 133 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 344 355 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 83 96 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 109 117 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 134 149 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 287 301 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 PRINTS PR00415 Aconitase family signature 400 413 5.3E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS13600 fc43eab12f59aa9ec601a6c75a6a3ed6 471 SUPERFAMILY SSF53732 2 466 9.16E-146 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 hmeg3_RS05325 74f711aa9181afbba1526a70ec44077d 140 SMART SM00448 18 129 2.5E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05325 74f711aa9181afbba1526a70ec44077d 140 Pfam PF00072 Response regulator receiver domain 20 129 1.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05325 74f711aa9181afbba1526a70ec44077d 140 SUPERFAMILY SSF52172 20 135 2.56E-25 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05325 74f711aa9181afbba1526a70ec44077d 140 Gene3D G3DSA:3.40.50.2300 1 140 3.3E-25 T 28-03-2018 hmeg3_RS04725 cce4078d329d67b71d170f3c17340d9b 234 SUPERFAMILY SSF90257 53 113 8.11E-5 T 28-03-2018 hmeg3_RS04725 cce4078d329d67b71d170f3c17340d9b 234 Gene3D G3DSA:1.20.5.10 105 140 0.024 T 28-03-2018 hmeg3_RS04725 cce4078d329d67b71d170f3c17340d9b 234 Gene3D G3DSA:1.20.5.340 50 104 2.2E-7 T 28-03-2018 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 17 478 31.363 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 18 324 1.9E-104 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 SUPERFAMILY SSF48163 318 477 3.92E-37 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 3.8E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 3.8E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 33 3.8E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 46 3.8E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 PRINTS PR00987 Glutamyl-tRNA synthetase signature 50 63 3.8E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 18 476 8.7E-171 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 24 35 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Gene3D G3DSA:3.40.50.620 13 137 1.5E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Gene3D G3DSA:1.10.8.70 336 379 1.7E-6 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Gene3D G3DSA:1.10.1160.10 251 332 5.2E-35 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 SUPERFAMILY SSF52374 17 317 6.97E-113 T 28-03-2018 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Gene3D G3DSA:1.10.10.350 385 478 8.3E-17 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 hmeg3_RS15170 f624506af032e9bd6f8bd5868329576e 478 Gene3D G3DSA:3.40.50.620 138 250 2.6E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 Pfam PF03466 LysR substrate binding domain 90 286 6.8E-35 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 SUPERFAMILY SSF53850 90 288 1.09E-32 T 28-03-2018 hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 Gene3D G3DSA:1.10.10.10 1 86 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 SUPERFAMILY SSF46785 4 113 2.11E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 Gene3D G3DSA:3.40.190.10 182 267 1.1E-14 T 28-03-2018 hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 Gene3D G3DSA:3.40.190.10 91 181 1.4E-20 T 28-03-2018 hmeg3_RS12720 effbdadb7318e8363094a17662275761 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 SUPERFAMILY SSF53822 32 374 2.56E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 7.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 97 107 7.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 263 281 7.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 Gene3D G3DSA:3.40.50.2300 211 361 7.8E-22 T 28-03-2018 hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 Gene3D G3DSA:3.40.50.2300 28 210 7.5E-26 T 28-03-2018 hmeg3_RS22110 9313812b5e986f66b0f15d302e5764ff 384 Pfam PF13458 Periplasmic binding protein 32 370 4.3E-57 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 Pfam PF16925 Bacterial transcriptional repressor C-terminal 78 188 3.0E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 52 7.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 SUPERFAMILY SSF46689 3 63 7.48E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 SUPERFAMILY SSF48498 76 186 6.68E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 Gene3D G3DSA:1.10.357.10 57 188 2.0E-23 T 28-03-2018 hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS05845 ac06d80cb4cd44f838de5fb1add619cb 191 Gene3D G3DSA:1.10.10.60 2 56 4.3E-20 T 28-03-2018 hmeg3_RS24355 0022ec8e298fc627c647a4900f9b0bcf 66 Gene3D G3DSA:3.30.70.20 1 65 3.5E-9 T 28-03-2018 hmeg3_RS24355 0022ec8e298fc627c647a4900f9b0bcf 66 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS24355 0022ec8e298fc627c647a4900f9b0bcf 66 Pfam PF00037 4Fe-4S binding domain 39 60 3.1E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS24355 0022ec8e298fc627c647a4900f9b0bcf 66 SUPERFAMILY SSF54862 1 62 7.61E-11 T 28-03-2018 hmeg3_RS03585 3a201d1271e5d8d27522e8afe89c3ca4 162 Gene3D G3DSA:2.30.30.220 7 103 5.6E-37 T 28-03-2018 IPR007481 Stringent starvation protein B hmeg3_RS03585 3a201d1271e5d8d27522e8afe89c3ca4 162 PIRSF PIRSF005276 1 162 1.5E-50 T 28-03-2018 IPR007481 Stringent starvation protein B hmeg3_RS03585 3a201d1271e5d8d27522e8afe89c3ca4 162 SUPERFAMILY SSF101738 3 113 1.7E-45 T 28-03-2018 IPR007481 Stringent starvation protein B hmeg3_RS03585 3a201d1271e5d8d27522e8afe89c3ca4 162 Pfam PF04386 Stringent starvation protein B 5 160 1.8E-36 T 28-03-2018 IPR007481 Stringent starvation protein B hmeg3_RS01110 dac9d209b11a81603a56247d4915b757 139 Gene3D G3DSA:3.10.129.10 1 139 2.8E-25 T 28-03-2018 hmeg3_RS01110 dac9d209b11a81603a56247d4915b757 139 Pfam PF13279 Thioesterase-like superfamily 11 132 1.2E-10 T 28-03-2018 hmeg3_RS01110 dac9d209b11a81603a56247d4915b757 139 SUPERFAMILY SSF54637 1 137 9.08E-32 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 Gene3D G3DSA:3.30.420.40 13 198 4.1E-53 T 28-03-2018 hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 Gene3D G3DSA:3.30.420.40 228 388 8.3E-25 T 28-03-2018 hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 14 387 40.825 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 SUPERFAMILY SSF53067 80 125 3.93E-26 T 28-03-2018 hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 SUPERFAMILY SSF53067 155 359 3.93E-26 T 28-03-2018 hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 SUPERFAMILY SSF53067 15 50 3.93E-26 T 28-03-2018 hmeg3_RS21685 6a3c48a5bcb8aa0a01a730b9b35cf854 388 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 15 387 1.4E-134 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 hmeg3_RS06605 c72cdac6d329b43e6c5cc1822de21818 88 Pfam PF01649 Ribosomal protein S20 2 84 6.7E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS06605 c72cdac6d329b43e6c5cc1822de21818 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 2.4E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS06605 c72cdac6d329b43e6c5cc1822de21818 88 SUPERFAMILY SSF46992 3 86 7.19E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS06605 c72cdac6d329b43e6c5cc1822de21818 88 Gene3D G3DSA:1.20.58.110 1 88 5.5E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS06605 c72cdac6d329b43e6c5cc1822de21818 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 20 70 9.0E-9 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS06605 c72cdac6d329b43e6c5cc1822de21818 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.621 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Gene3D G3DSA:3.40.50.300 1 144 9.3E-29 T 28-03-2018 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Gene3D G3DSA:1.10.3710.10 333 430 3.7E-33 T 28-03-2018 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 SUPERFAMILY SSF52540 5 220 6.42E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Gene3D G3DSA:1.10.8.60 145 227 3.5E-20 T 28-03-2018 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Pfam PF16193 AAA C-terminal domain 176 251 9.8E-22 T 28-03-2018 IPR032423 AAA C-terminal domain hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 418 1.3E-64 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 SUPERFAMILY SSF48019 236 418 3.74E-72 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 43 150 4.9E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 Gene3D G3DSA:1.20.272.10 236 330 2.7E-37 T 28-03-2018 hmeg3_RS16815 8615c9037407d618b4060cfb22d68dfd 430 SMART SM00382 39 156 4.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02995 073d34bef111f86cdc054256d252a590 366 Gene3D G3DSA:1.10.3470.10 18 354 2.4E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS02995 073d34bef111f86cdc054256d252a590 366 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 350 2.5E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 SMART SM00283 268 515 3.5E-92 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 188 1.2E-11 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 Gene3D G3DSA:1.10.287.950 323 519 9.3E-50 T 28-03-2018 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 Gene3D G3DSA:1.10.287.950 80 322 1.8E-16 T 28-03-2018 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 SUPERFAMILY SSF58104 235 516 1.31E-76 T 28-03-2018 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 424 2.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 366 393 2.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 443 472 2.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 289 318 2.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 483 2.2E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 SMART SM00304 215 267 9.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS03990 ad957e2b331aa139991f9b32fceec5c6 566 Pfam PF00672 HAMP domain 215 258 1.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 275 290 1.1E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 226 246 1.1E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 6 468 31.371 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Pfam PF12631 MnmE helical domain 130 465 3.2E-52 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 373 1.0E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Gene3D G3DSA:1.20.120.430 129 287 2.1E-22 T 28-03-2018 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 468 6.2E-101 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Pfam PF10396 GTP-binding protein TrmE N-terminus 7 127 6.1E-38 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Gene3D G3DSA:3.30.1360.120 1 128 1.1E-43 T 28-03-2018 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 SUPERFAMILY SSF116878 388 468 1.83E-46 T 28-03-2018 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 SUPERFAMILY SSF116878 128 227 1.83E-46 T 28-03-2018 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 SUPERFAMILY SSF52540 75 185 1.17E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 SUPERFAMILY SSF52540 219 380 1.17E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Gene3D G3DSA:1.20.120.430 291 468 4.6E-31 T 28-03-2018 hmeg3_RS02600 0741ad3828c0b88a68bbed5865dc4929 468 Pfam PF01926 50S ribosome-binding GTPase 225 344 1.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS17420 fc3f808b670a458eba51151c883c4c0f 542 Gene3D G3DSA:3.40.720.10 158 516 4.4E-27 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 hmeg3_RS17420 fc3f808b670a458eba51151c883c4c0f 542 TIGRFAM TIGR03397 acid_phos_Burk: acid phosphatase, Burkholderia-type 45 537 1.3E-230 T 28-03-2018 IPR017768 Acid phosphatase, AcpA GO:0003993 hmeg3_RS17420 fc3f808b670a458eba51151c883c4c0f 542 SUPERFAMILY SSF53649 306 497 8.37E-21 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 hmeg3_RS17420 fc3f808b670a458eba51151c883c4c0f 542 SUPERFAMILY SSF53649 186 227 8.37E-21 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 hmeg3_RS17420 fc3f808b670a458eba51151c883c4c0f 542 Pfam PF04185 Phosphoesterase family 45 510 7.7E-102 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.1E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 SUPERFAMILY SSF47413 3 60 8.13E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 Gene3D G3DSA:1.10.260.40 4 58 4.0E-19 T 28-03-2018 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 Pfam PF13377 Periplasmic binding protein-like domain 170 311 5.5E-30 T 28-03-2018 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 Gene3D G3DSA:3.40.50.2300 59 175 1.7E-33 T 28-03-2018 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 SUPERFAMILY SSF53822 59 313 4.08E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 SMART SM00354 2 72 5.2E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS20475 524268b408ead51dbb7e7f2e43fac797 339 Gene3D G3DSA:3.40.50.2300 176 309 3.3E-36 T 28-03-2018 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Pfam PF00308 Bacterial dnaA protein 141 357 2.5E-84 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Pfam PF11638 DnaA N-terminal domain 3 64 4.6E-19 T 28-03-2018 IPR024633 DnaA N-terminal domain hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 474 31.277 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 SUPERFAMILY SSF52540 143 351 1.41E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 SUPERFAMILY SSF48295 371 474 4.97E-37 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 SMART SM00760 383 452 7.2E-44 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 271 298 3.8E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 237 251 3.8E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 219 3.8E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 433 452 3.8E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 173 193 3.8E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Gene3D G3DSA:1.10.8.60 306 376 5.9E-27 T 28-03-2018 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Gene3D G3DSA:1.10.1750.10 377 474 2.2E-35 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 ProSitePatterns PS01008 DnaA protein signature. 433 452 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 SMART SM00382 172 303 5.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Gene3D G3DSA:3.40.50.300 137 304 3.2E-19 T 28-03-2018 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 473 7.4E-170 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 hmeg3_RS24265 27e791b714f07a2fc2d0dea67b13dc24 475 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 384 452 1.8E-32 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 SUPERFAMILY SSF54826 1 112 4.42E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 Pfam PF13378 Enolase C-terminal domain-like 129 355 9.3E-65 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 2.1E-26 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 SUPERFAMILY SSF51604 95 359 4.06E-82 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 Gene3D G3DSA:3.20.20.120 98 353 4.8E-79 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 Gene3D G3DSA:3.30.390.10 12 97 1.1E-29 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS19045 6a584f338be0867e5b7fbed9686a8f92 382 SMART SM00922 125 230 1.6E-24 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Pfam PF00072 Response regulator receiver domain 935 1045 1.8E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Pfam PF00512 His Kinase A (phospho-acceptor) domain 687 753 7.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Gene3D G3DSA:3.30.565.10 748 910 2.2E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 SUPERFAMILY SSF52172 931 1053 1.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 SMART SM00387 800 911 5.3E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 PRINTS PR00344 Bacterial sensor protein C-terminal signature 836 850 1.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 PRINTS PR00344 Bacterial sensor protein C-terminal signature 895 908 1.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 PRINTS PR00344 Bacterial sensor protein C-terminal signature 871 889 1.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 PRINTS PR00344 Bacterial sensor protein C-terminal signature 854 864 1.5E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 SMART SM00448 933 1045 9.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 SUPERFAMILY SSF47384 673 755 5.49E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Gene3D G3DSA:3.30.450.20 377 690 1.3E-4 T 28-03-2018 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Gene3D G3DSA:1.10.287.130 691 747 4.1E-18 T 28-03-2018 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 SUPERFAMILY SSF55874 743 907 2.23E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Gene3D G3DSA:3.40.50.2300 927 1075 3.3E-30 T 28-03-2018 hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 801 908 2.6E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS01455 c4b2b7cca26cb03fe301fb3b63977bd8 1155 SMART SM00388 687 753 2.2E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 PIRSF PIRSF005962 1 397 2.7E-135 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 Gene3D G3DSA:3.40.630.10 2 216 1.6E-52 T 28-03-2018 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 Gene3D G3DSA:3.40.630.10 249 397 1.6E-25 T 28-03-2018 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 SUPERFAMILY SSF55031 183 296 1.44E-31 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 382 2.0E-115 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 Pfam PF07687 Peptidase dimerisation domain 186 281 2.2E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 SUPERFAMILY SSF53187 298 395 9.43E-91 T 28-03-2018 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 SUPERFAMILY SSF53187 2 197 9.43E-91 T 28-03-2018 hmeg3_RS04580 694820f68c5ad7e22bd84083bc6ed282 397 Pfam PF01546 Peptidase family M20/M25/M40 73 391 8.3E-40 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 SUPERFAMILY SSF55031 189 302 6.8E-33 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 SUPERFAMILY SSF53187 10 203 1.79E-84 T 28-03-2018 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 SUPERFAMILY SSF53187 304 390 1.79E-84 T 28-03-2018 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 Gene3D G3DSA:3.40.630.10 265 392 4.9E-24 T 28-03-2018 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 Gene3D G3DSA:3.40.630.10 7 264 1.5E-48 T 28-03-2018 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 Pfam PF07687 Peptidase dimerisation domain 191 287 9.3E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 377 4.0E-111 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 PIRSF PIRSF005962 4 392 1.1E-125 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS03890 d5722f8861cd9805786f1a4f40bc6d9d 392 Pfam PF01546 Peptidase family M20/M25/M40 77 387 9.4E-34 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 PIRSF PIRSF000524 4 377 5.1E-60 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 Gene3D G3DSA:3.90.1150.10 258 370 5.0E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 Pfam PF00266 Aminotransferase class-V 31 317 3.0E-26 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 12 365 1.6E-149 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 SUPERFAMILY SSF53383 12 369 3.17E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 Gene3D G3DSA:3.40.640.10 21 257 9.0E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 9 366 8.9E-159 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 hmeg3_RS09375 eabc274630c59fc486a41ec569ce0aac 377 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 374 201.704 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 hmeg3_RS05445 74291fb289a5c5708f403b89dc473a43 478 Pfam PF00929 Exonuclease 7 188 2.7E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS05445 74291fb289a5c5708f403b89dc473a43 478 Gene3D G3DSA:3.30.420.10 1 197 8.9E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS05445 74291fb289a5c5708f403b89dc473a43 478 SUPERFAMILY SSF53098 5 463 5.16E-122 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS05445 74291fb289a5c5708f403b89dc473a43 478 Pfam PF08411 Exonuclease C-terminal 209 471 1.5E-99 T 28-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 hmeg3_RS05445 74291fb289a5c5708f403b89dc473a43 478 PIRSF PIRSF000977 1 478 8.0E-205 T 28-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 hmeg3_RS17440 d5c42d29e0efea6aa0b82b1b9aecbb5e 257 Gene3D G3DSA:1.10.3720.10 14 256 6.7E-27 T 28-03-2018 hmeg3_RS17440 d5c42d29e0efea6aa0b82b1b9aecbb5e 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 238 7.7E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17440 d5c42d29e0efea6aa0b82b1b9aecbb5e 257 SUPERFAMILY SSF161098 57 240 2.49E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09350 9e0da9b8d2fe0545b21e44f78c1c3fd7 419 Gene3D G3DSA:3.30.1360.110 254 361 1.7E-41 T 28-03-2018 IPR023116 Phosphonoacetate hydrolase, insert domain KEGG: 00440+3.11.1.2 hmeg3_RS09350 9e0da9b8d2fe0545b21e44f78c1c3fd7 419 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 19 352 5.9E-30 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 hmeg3_RS09350 9e0da9b8d2fe0545b21e44f78c1c3fd7 419 SUPERFAMILY SSF53649 5 402 1.18E-105 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 hmeg3_RS09350 9e0da9b8d2fe0545b21e44f78c1c3fd7 419 TIGRFAM TIGR02335 hydr_PhnA: phosphonoacetate hydrolase 5 406 1.5E-184 T 28-03-2018 IPR012710 Phosphonoacetate hydrolase GO:0047400 KEGG: 00440+3.11.1.2 hmeg3_RS09350 9e0da9b8d2fe0545b21e44f78c1c3fd7 419 Gene3D G3DSA:3.40.720.10 17 132 2.7E-9 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 hmeg3_RS07090 cb530a675351f655e664e4b2901b6dab 273 SMART SM00382 49 244 1.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07090 cb530a675351f655e664e4b2901b6dab 273 SUPERFAMILY SSF52540 20 246 2.92E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07090 cb530a675351f655e664e4b2901b6dab 273 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS07090 cb530a675351f655e664e4b2901b6dab 273 Gene3D G3DSA:3.40.50.300 15 253 5.5E-63 T 28-03-2018 hmeg3_RS07090 cb530a675351f655e664e4b2901b6dab 273 Pfam PF00005 ABC transporter 40 179 4.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07105 d717a6b41d07a24c3226d824f9617267 228 Gene3D G3DSA:2.60.120.620 3 188 2.1E-30 T 28-03-2018 hmeg3_RS07105 d717a6b41d07a24c3226d824f9617267 228 SMART SM00702 1 179 5.1E-17 T 28-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 hmeg3_RS07105 d717a6b41d07a24c3226d824f9617267 228 SUPERFAMILY SSF51197 5 180 3.75E-5 T 28-03-2018 hmeg3_RS07105 d717a6b41d07a24c3226d824f9617267 228 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 85 178 2.8E-14 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 hmeg3_RS07105 d717a6b41d07a24c3226d824f9617267 228 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 228 44.267 T 28-03-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 hmeg3_RS23590 a3c9ab8d6b087ff1b1618d893640f790 452 Gene3D G3DSA:1.20.1250.20 239 445 1.4E-21 T 28-03-2018 hmeg3_RS23590 a3c9ab8d6b087ff1b1618d893640f790 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS23590 a3c9ab8d6b087ff1b1618d893640f790 452 SUPERFAMILY SSF103473 12 433 6.28E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS23590 a3c9ab8d6b087ff1b1618d893640f790 452 Gene3D G3DSA:1.20.1250.20 13 213 1.8E-36 T 28-03-2018 hmeg3_RS23590 a3c9ab8d6b087ff1b1618d893640f790 452 Pfam PF07690 Major Facilitator Superfamily 28 293 7.3E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 2.1E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 Gene3D G3DSA:1.10.10.60 11 53 1.4E-15 T 28-03-2018 hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 SUPERFAMILY SSF46689 14 82 2.46E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 Gene3D G3DSA:1.10.10.60 54 194 9.3E-10 T 28-03-2018 hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS04170 a8ca7aa556bfbf888e8d063a7a06b650 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 SUPERFAMILY SSF51735 6 258 8.78E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 Gene3D G3DSA:3.40.50.720 4 261 2.7E-63 T 28-03-2018 hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 258 1.2E-46 T 28-03-2018 hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23840 6f95597e1d5e6627e4d3d5575500258d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 SUPERFAMILY SSF52540 3 223 7.66E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 SUPERFAMILY SSF52540 243 494 4.76E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 Pfam PF00005 ABC transporter 20 171 2.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 Pfam PF00005 ABC transporter 280 435 1.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 Gene3D G3DSA:3.40.50.300 1 253 3.3E-48 T 28-03-2018 hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 SMART SM00382 29 234 5.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 SMART SM00382 288 485 5.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19000 efcdb2451e3a8803b6d1338f2ca74136 512 Gene3D G3DSA:3.40.50.300 255 507 1.1E-38 T 28-03-2018 hmeg3_RS01320 fd70209aa2bb47c066c86f55e050ada2 392 Pfam PF13458 Periplasmic binding protein 29 358 7.6E-66 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS01320 fd70209aa2bb47c066c86f55e050ada2 392 Gene3D G3DSA:3.40.50.2300 194 354 1.1E-19 T 28-03-2018 hmeg3_RS01320 fd70209aa2bb47c066c86f55e050ada2 392 Gene3D G3DSA:3.40.50.2300 13 193 1.1E-29 T 28-03-2018 hmeg3_RS01320 fd70209aa2bb47c066c86f55e050ada2 392 SUPERFAMILY SSF53822 29 390 2.07E-77 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01345 a1b908149f8f951f0d7a5cd3cd30b8f6 287 Pfam PF07859 alpha/beta hydrolase fold 80 187 1.1E-14 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS01345 a1b908149f8f951f0d7a5cd3cd30b8f6 287 Gene3D G3DSA:3.40.50.1820 36 284 6.6E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01345 a1b908149f8f951f0d7a5cd3cd30b8f6 287 SUPERFAMILY SSF53474 25 270 1.73E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06335 b7dec3bab4ba7320978e302d36e2a880 152 Pfam PF05232 Chlorhexidine efflux transporter 82 144 3.0E-24 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter hmeg3_RS06335 b7dec3bab4ba7320978e302d36e2a880 152 Pfam PF05232 Chlorhexidine efflux transporter 5 68 7.6E-25 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter hmeg3_RS08020 47d892e337c2618d6266c352f8b24590 307 Pfam PF07859 alpha/beta hydrolase fold 83 199 1.4E-21 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS08020 47d892e337c2618d6266c352f8b24590 307 Gene3D G3DSA:3.40.50.1820 204 304 0.1 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS08020 47d892e337c2618d6266c352f8b24590 307 SUPERFAMILY SSF53474 36 301 1.1E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS08020 47d892e337c2618d6266c352f8b24590 307 Gene3D G3DSA:3.40.50.1820 32 203 1.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 Gene3D G3DSA:3.90.1150.10 361 485 1.2E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 SUPERFAMILY SSF53383 112 483 5.19E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 7.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 SMART SM00345 16 75 7.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 Gene3D G3DSA:1.10.10.10 1 87 6.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 SUPERFAMILY SSF46785 7 79 3.93E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 Gene3D G3DSA:3.40.640.10 143 360 6.5E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS14150 428d71e3b02fc52919187c2b4db220df 485 Pfam PF00155 Aminotransferase class I and II 162 477 1.8E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 PIRSF PIRSF003101 1 410 7.9E-153 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 SUPERFAMILY SSF53067 197 376 5.56E-48 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Pfam PF14450 Cell division protein FtsA 10 189 6.8E-11 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Pfam PF14450 Cell division protein FtsA 206 373 1.9E-26 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 2.0E-32 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 410 31.573 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Gene3D G3DSA:3.30.420.40 1 185 4.3E-39 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Gene3D G3DSA:3.30.420.40 258 351 3.5E-19 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 Gene3D G3DSA:3.30.420.40 196 257 2.5E-8 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 376 1.3E-148 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 SUPERFAMILY SSF53067 8 196 4.37E-62 T 28-03-2018 hmeg3_RS21990 cb238ec445768e02bb35f4e289182e9e 410 SMART SM00842 9 195 7.4E-103 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 Pfam PF03466 LysR substrate binding domain 87 302 3.5E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 Gene3D G3DSA:3.40.190.10 176 277 3.9E-19 T 28-03-2018 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 SUPERFAMILY SSF53850 87 307 3.26E-30 T 28-03-2018 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 SUPERFAMILY SSF46785 1 84 9.98E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 Gene3D G3DSA:3.40.190.10 88 175 6.6E-18 T 28-03-2018 hmeg3_RS20695 2e59b2f8592688d72897cd9b19ac47ac 311 Gene3D G3DSA:1.10.10.10 1 86 2.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22700 af0f3ceec03f8c6e6ab7800b7145545d 212 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 195 7.2E-9 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS22700 af0f3ceec03f8c6e6ab7800b7145545d 212 PIRSF PIRSF000239 1 209 8.1E-77 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS22700 af0f3ceec03f8c6e6ab7800b7145545d 212 SUPERFAMILY SSF52833 3 209 1.68E-65 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS22700 af0f3ceec03f8c6e6ab7800b7145545d 212 Gene3D G3DSA:3.30.1020.10 152 212 6.5E-23 T 28-03-2018 hmeg3_RS22700 af0f3ceec03f8c6e6ab7800b7145545d 212 Pfam PF00578 AhpC/TSA family 6 135 8.3E-31 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS22700 af0f3ceec03f8c6e6ab7800b7145545d 212 Gene3D G3DSA:3.40.30.10 1 151 8.8E-40 T 28-03-2018 hmeg3_RS08930 2b8606919f3af7614f8ec881192921fd 351 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 103 5.9E-6 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS08930 2b8606919f3af7614f8ec881192921fd 351 Gene3D G3DSA:3.40.50.720 2 351 1.3E-32 T 28-03-2018 hmeg3_RS08930 2b8606919f3af7614f8ec881192921fd 351 SUPERFAMILY SSF51735 302 347 2.5E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08930 2b8606919f3af7614f8ec881192921fd 351 SUPERFAMILY SSF51735 5 264 2.5E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08010 46b0c6405bfae3b8d10df027ad54aec8 247 SUPERFAMILY SSF161098 48 233 3.4E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS08010 46b0c6405bfae3b8d10df027ad54aec8 247 Gene3D G3DSA:1.10.3720.10 43 242 2.0E-24 T 28-03-2018 hmeg3_RS08010 46b0c6405bfae3b8d10df027ad54aec8 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 238 2.6E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS06765 7fd97528f48de0127e66c44f5ce82de4 609 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 49 606 8.0E-240 T 28-03-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 hmeg3_RS06765 7fd97528f48de0127e66c44f5ce82de4 609 Gene3D G3DSA:3.90.1300.10 10 477 6.4E-112 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS06765 7fd97528f48de0127e66c44f5ce82de4 609 Pfam PF01425 Amidase 56 450 1.4E-85 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS06765 7fd97528f48de0127e66c44f5ce82de4 609 SUPERFAMILY SSF75304 14 461 5.89E-113 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS06765 7fd97528f48de0127e66c44f5ce82de4 609 Gene3D G3DSA:3.10.490.10 478 609 1.1E-25 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 Gene3D G3DSA:1.20.1250.20 4 188 7.2E-28 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 Pfam PF07690 Major Facilitator Superfamily 13 404 2.0E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 382 401 5.2E-10 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 5.2E-10 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 5.2E-10 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 5.2E-10 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 5.2E-10 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 Gene3D G3DSA:1.20.1250.20 254 466 2.1E-19 T 28-03-2018 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 415 4.9E-69 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 SUPERFAMILY SSF103473 244 451 1.07E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS15940 0e1e9d1c424a8ba1d82438d70c289c40 474 SUPERFAMILY SSF103473 11 198 1.07E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10845 f19d138bd3a9624bbcb0346162c0abc2 325 Gene3D G3DSA:3.40.50.10330 1 136 9.3E-26 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 hmeg3_RS10845 f19d138bd3a9624bbcb0346162c0abc2 325 Pfam PF00781 Diacylglycerol kinase catalytic domain 10 132 4.3E-24 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 hmeg3_RS10845 f19d138bd3a9624bbcb0346162c0abc2 325 SMART SM00046 10 135 1.2E-8 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 hmeg3_RS10845 f19d138bd3a9624bbcb0346162c0abc2 325 SUPERFAMILY SSF111331 9 306 1.4E-63 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 Gene3D G3DSA:3.40.50.300 224 466 8.0E-45 T 28-03-2018 hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 Pfam PF00270 DEAD/DEAH box helicase 25 197 1.1E-47 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 SUPERFAMILY SSF52540 77 362 1.69E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 Gene3D G3DSA:3.40.50.300 7 223 8.1E-61 T 28-03-2018 hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 462 50.814 T 28-03-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 SMART SM00490 260 341 1.3E-31 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 SMART SM00487 20 221 8.7E-60 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 Pfam PF00271 Helicase conserved C-terminal domain 235 341 7.8E-28 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS14050 7a4a5fb952cfbff7aa5ec0f42f1b2921 466 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SUPERFAMILY SSF47384 478 561 4.71E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SUPERFAMILY SSF52172 803 918 1.57E-25 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SMART SM00065 261 403 0.0025 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Gene3D G3DSA:1.10.287.130 482 556 2.1E-17 T 28-03-2018 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SUPERFAMILY SSF52172 921 1051 3.7E-22 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SUPERFAMILY SSF52172 1069 1194 1.28E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Gene3D G3DSA:3.40.50.2300 1067 1196 2.8E-39 T 28-03-2018 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SMART SM00448 803 913 6.4E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SMART SM00448 925 1039 5.8E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SMART SM00448 1071 1190 6.8E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SMART SM00388 492 560 6.6E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SUPERFAMILY SSF55781 234 393 7.46E-15 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SUPERFAMILY SSF55874 549 717 1.17E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF13185 GAF domain 260 391 3.8E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 PRINTS PR00344 Bacterial sensor protein C-terminal signature 662 672 4.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 PRINTS PR00344 Bacterial sensor protein C-terminal signature 703 716 4.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 658 4.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 697 4.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Gene3D G3DSA:3.30.450.40 232 425 1.4E-18 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF00512 His Kinase A (phospho-acceptor) domain 493 560 3.8E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF00072 Response regulator receiver domain 805 913 5.9E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF00072 Response regulator receiver domain 1073 1190 6.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF00072 Response regulator receiver domain 927 1037 9.2E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF05227 CHASE3 domain 66 200 7.1E-45 T 28-03-2018 IPR007891 CHASE3 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Gene3D G3DSA:3.30.565.10 565 727 2.0E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Gene3D G3DSA:3.40.50.2300 794 921 6.0E-24 T 28-03-2018 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Gene3D G3DSA:3.40.50.2300 922 1066 5.0E-22 T 28-03-2018 hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 608 716 8.9E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23490 1d0f7ddb205bd03443922b7d31a901bb 1196 SMART SM00387 607 719 1.1E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 30 570 1.1E-239 T 28-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 SUPERFAMILY SSF161098 27 278 1.01E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 SUPERFAMILY SSF161098 311 554 4.49E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 Gene3D G3DSA:1.10.3720.10 27 290 4.2E-37 T 28-03-2018 hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 Gene3D G3DSA:1.10.3720.10 307 567 8.0E-22 T 28-03-2018 hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 285 1.2E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09370 5cd0ec08255dd3fc64ff9a7cd7c59912 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 391 561 7.3E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 Gene3D G3DSA:1.10.287.130 215 285 1.2E-8 T 28-03-2018 hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 8.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 420 8.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 SUPERFAMILY SSF47384 208 287 3.34E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 SUPERFAMILY SSF55874 279 440 1.96E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 425 2.2E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 SMART SM00387 335 442 2.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 282 5.9E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 Gene3D G3DSA:3.30.565.10 296 446 1.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 Pfam PF08521 Two-component sensor kinase N-terminal 15 147 2.5E-29 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal hmeg3_RS10930 dc88e020ffd936b91ebc1f805c9a8ede 446 SMART SM00388 225 290 3.7E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 SUPERFAMILY SSF88946 18 123 1.83E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 188 2.1E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 Gene3D G3DSA:1.10.1740.10 25 109 3.5E-19 T 28-03-2018 hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 Pfam PF04542 Sigma-70 region 2 42 106 2.5E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 SUPERFAMILY SSF88659 131 188 1.87E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 Gene3D G3DSA:1.10.10.10 131 192 2.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13165 8091c6a47a0b8e5475cbd1b1f9726baa 194 Pfam PF08281 Sigma-70, region 4 136 186 3.4E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS04250 daeeaf42e9561549a3694bf420e2f6f1 405 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 25 388 6.3E-99 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB hmeg3_RS04250 daeeaf42e9561549a3694bf420e2f6f1 405 SUPERFAMILY SSF103473 11 395 6.28E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04250 daeeaf42e9561549a3694bf420e2f6f1 405 Gene3D G3DSA:1.20.1250.20 10 192 3.4E-9 T 28-03-2018 hmeg3_RS04250 daeeaf42e9561549a3694bf420e2f6f1 405 Gene3D G3DSA:1.20.1250.20 215 404 1.2E-14 T 28-03-2018 hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 Gene3D G3DSA:1.10.10.10 1 91 3.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.1E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.1E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.1E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 SUPERFAMILY SSF46785 2 93 3.16E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 SMART SM00418 8 88 5.8E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS13090 c740001fdfa2af06a4afa04f81e95c21 111 Pfam PF12840 Helix-turn-helix domain 10 69 1.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03115 ef05befa32a068ede040a6285e1e2dac 430 Gene3D G3DSA:3.40.50.10840 9 243 1.8E-78 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain hmeg3_RS03115 ef05befa32a068ede040a6285e1e2dac 430 Pfam PF07005 Putative sugar-binding N-terminal domain 10 234 3.0E-73 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain hmeg3_RS03115 ef05befa32a068ede040a6285e1e2dac 430 SUPERFAMILY SSF142764 10 425 6.02E-129 T 28-03-2018 hmeg3_RS03115 ef05befa32a068ede040a6285e1e2dac 430 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 262 418 3.4E-44 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 363 505 5.5E-14 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 SUPERFAMILY SSF56645 123 358 3.8E-46 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 SUPERFAMILY SSF47203 363 510 2.09E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 Pfam PF09317 Domain of unknown function (DUF1974) 517 807 1.5E-106 T 28-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 Gene3D G3DSA:1.20.140.10 353 511 3.3E-26 T 28-03-2018 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 Gene3D G3DSA:2.40.110.10 239 352 2.7E-16 T 28-03-2018 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 Gene3D G3DSA:1.10.540.10 79 238 9.0E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS05205 4db567d1405ad7a7eabd0c8b8776f3ef 829 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 128 236 3.4E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Gene3D G3DSA:1.20.5.1040 152 197 1.0E-5 T 28-03-2018 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Gene3D G3DSA:1.20.5.1040 11 63 5.6E-4 T 28-03-2018 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 323 7.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 5.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 SUPERFAMILY SSF47384 233 323 2.16E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Gene3D G3DSA:3.30.565.10 329 491 1.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 SMART SM00387 368 489 7.1E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Pfam PF08521 Two-component sensor kinase N-terminal 25 173 3.1E-41 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 SMART SM00388 250 323 3.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 486 2.7E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 SUPERFAMILY SSF55874 312 487 1.31E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02695 ccea0c90f8e16035a9d64304d64eba2d 491 Gene3D G3DSA:1.10.287.130 240 319 5.6E-11 T 28-03-2018 hmeg3_RS06675 18f4aeb4cd5b6efb38b4886e0d935f06 264 Pfam PF08241 Methyltransferase domain 78 170 3.0E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS06675 18f4aeb4cd5b6efb38b4886e0d935f06 264 SUPERFAMILY SSF53335 23 220 5.63E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS06675 18f4aeb4cd5b6efb38b4886e0d935f06 264 Gene3D G3DSA:3.40.50.150 38 214 7.9E-22 T 28-03-2018 hmeg3_RS04670 c34a005ccffc4aa5f39d77040bb770ed 304 SMART SM00062 42 274 5.0E-40 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04670 c34a005ccffc4aa5f39d77040bb770ed 304 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 272 8.6E-42 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04670 c34a005ccffc4aa5f39d77040bb770ed 304 SUPERFAMILY SSF53850 17 274 9.37E-53 T 28-03-2018 hmeg3_RS04670 c34a005ccffc4aa5f39d77040bb770ed 304 Gene3D G3DSA:3.40.190.10 168 274 7.8E-12 T 28-03-2018 hmeg3_RS04670 c34a005ccffc4aa5f39d77040bb770ed 304 SMART SM00079 42 273 7.5E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS04670 c34a005ccffc4aa5f39d77040bb770ed 304 Gene3D G3DSA:3.40.190.10 22 167 5.9E-25 T 28-03-2018 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 Hamap MF_00013 Octanoyltransferase [lipB]. 4 215 33.513 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 74 131 4.0E-14 T 28-03-2018 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 Gene3D G3DSA:3.30.930.10 1 213 4.6E-54 T 28-03-2018 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 28 210 8.6E-51 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 SUPERFAMILY SSF55681 5 213 5.8E-58 T 28-03-2018 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 PIRSF PIRSF016262 1 218 2.1E-53 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 70 85 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 hmeg3_RS24080 0f4fcc949b0ca1706f6cc59666f121ae 218 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 167 2.9E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 hmeg3_RS21105 c512d8bfa2dd554b5492d30323facd21 215 Gene3D G3DSA:3.40.50.150 1 214 4.2E-30 T 28-03-2018 hmeg3_RS21105 c512d8bfa2dd554b5492d30323facd21 215 SUPERFAMILY SSF53335 1 173 5.17E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS21105 c512d8bfa2dd554b5492d30323facd21 215 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 9 191 1.5E-31 T 28-03-2018 hmeg3_RS21105 c512d8bfa2dd554b5492d30323facd21 215 SMART SM00650 65 203 0.0094 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 141 438 5.3E-51 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 Gene3D G3DSA:3.90.850.10 133 426 5.5E-83 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 Gene3D G3DSA:2.30.30.230 15 131 3.3E-27 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 Pfam PF09298 Fumarylacetoacetase N-terminal 30 135 6.3E-22 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 SUPERFAMILY SSF56529 137 441 3.66E-91 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 SUPERFAMILY SSF63433 14 135 2.48E-30 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 hmeg3_RS18530 727b162ac5638798ae475be622ffb3a8 444 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 15 441 9.7E-167 T 28-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 Pfam PF01380 SIS domain 59 189 9.8E-29 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 Pfam PF00571 CBS domain 287 339 5.4E-7 T 28-03-2018 IPR000644 CBS domain hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 Pfam PF00571 CBS domain 219 275 3.1E-6 T 28-03-2018 IPR000644 CBS domain hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 Gene3D G3DSA:3.40.50.10490 15 215 7.1E-53 T 28-03-2018 hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 63 332 5.2E-108 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 Gene3D G3DSA:3.10.580.10 216 342 1.3E-22 T 28-03-2018 hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 PIRSF PIRSF004692 9 342 2.7E-130 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 SMART SM00116 293 341 0.015 T 28-03-2018 IPR000644 CBS domain hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 SMART SM00116 228 276 14.0 T 28-03-2018 IPR000644 CBS domain hmeg3_RS04050 184ef5fd52596d1376649b02e90d39c8 342 SUPERFAMILY SSF53697 29 339 8.68E-67 T 28-03-2018 hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 Gene3D G3DSA:3.40.190.10 144 253 4.2E-9 T 28-03-2018 hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 Gene3D G3DSA:3.40.190.10 5 143 1.0E-33 T 28-03-2018 hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 SUPERFAMILY SSF53850 6 254 1.09E-54 T 28-03-2018 hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 SMART SM00062 35 255 1.0E-43 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 SMART SM00079 35 254 0.0077 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS03090 2fa558d97316dca6da71d88c95f63f6d 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 2.5E-50 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Gene3D G3DSA:3.50.50.60 415 487 1.6E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 SUPERFAMILY SSF51971 373 481 1.01E-10 T 28-03-2018 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 SUPERFAMILY SSF51971 142 410 5.65E-66 T 28-03-2018 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 3.6E-25 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 468 1.0E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 2.5E-21 T 28-03-2018 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 2.5E-21 T 28-03-2018 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 PRINTS PR00419 Adrenodoxin reductase family signature 296 310 2.5E-21 T 28-03-2018 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Gene3D G3DSA:3.50.50.60 337 410 0.016 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Gene3D G3DSA:3.50.50.60 253 336 1.9E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 486 6.3E-229 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 SUPERFAMILY SSF46548 2 154 4.19E-41 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Gene3D G3DSA:1.10.1060.10 3 143 2.9E-41 T 28-03-2018 hmeg3_RS04285 0396e2f6c35f90c1593a6a398df32f25 487 Gene3D G3DSA:3.40.50.720 144 252 8.6E-23 T 28-03-2018 hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 Pfam PF00106 short chain dehydrogenase 9 204 3.8E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 SUPERFAMILY SSF51735 7 268 9.11E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 2.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 Gene3D G3DSA:3.40.50.720 1 53 4.5E-13 T 28-03-2018 hmeg3_RS00125 dd68bec8562468b8a653021ee1e5cf6a 271 Gene3D G3DSA:3.40.50.720 54 271 5.4E-45 T 28-03-2018 hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 245 3.9E-55 T 28-03-2018 hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 Gene3D G3DSA:3.40.50.720 37 247 1.9E-57 T 28-03-2018 hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 Gene3D G3DSA:3.40.50.720 1 36 7.8E-7 T 28-03-2018 hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.1E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01845 64a8d4be262ff714e08b5b7d443c953b 247 SUPERFAMILY SSF51735 3 246 1.72E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01810 e8d2f09e0487e76f5dea23ed042e5d37 296 SMART SM00062 36 268 8.1E-51 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS01810 e8d2f09e0487e76f5dea23ed042e5d37 296 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 266 2.6E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS01810 e8d2f09e0487e76f5dea23ed042e5d37 296 Gene3D G3DSA:3.40.190.10 165 296 4.5E-13 T 28-03-2018 hmeg3_RS01810 e8d2f09e0487e76f5dea23ed042e5d37 296 SUPERFAMILY SSF53850 10 268 8.4E-59 T 28-03-2018 hmeg3_RS01810 e8d2f09e0487e76f5dea23ed042e5d37 296 Gene3D G3DSA:3.40.190.10 1 164 8.0E-33 T 28-03-2018 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 SUPERFAMILY SSF53271 71 304 5.59E-64 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 314 1.9E-27 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 315 49.425 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 Gene3D G3DSA:3.40.50.2020 159 316 3.3E-45 T 28-03-2018 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 Gene3D G3DSA:3.40.50.2020 3 158 5.6E-67 T 28-03-2018 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 4.6E-122 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 123 4.6E-49 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 hmeg3_RS04300 2221eed7866e49eb23eae97698a910c7 316 SMART SM01400 6 123 6.9E-78 T 28-03-2018 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 SMART SM01005 236 360 5.2E-65 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 Gene3D G3DSA:2.40.37.10 208 360 3.2E-58 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 TIGRFAM TIGR00492 alr: alanine racemase 4 356 1.4E-111 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 SUPERFAMILY SSF50621 230 357 6.63E-46 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 Hamap MF_01201 Alanine racemase. 2 360 33.647 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 Pfam PF00842 Alanine racemase, C-terminal domain 236 356 1.7E-40 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 Pfam PF01168 Alanine racemase, N-terminal domain 9 223 1.8E-64 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 SUPERFAMILY SSF51419 9 237 6.54E-60 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 27 43 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 61 79 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 342 355 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 123 135 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 269 284 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 157 168 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 196 223 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 252 267 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 PRINTS PR00992 Alanine racemase signature 290 307 4.2E-66 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 hmeg3_RS09800 ea6d6964c2a4d73f2039b321d59135a5 361 Gene3D G3DSA:3.20.20.10 6 207 9.9E-37 T 28-03-2018 IPR029066 PLP-binding barrel hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Gene3D G3DSA:3.40.50.620 2 666 4.0E-151 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Pfam PF09334 tRNA synthetases class I (M) 44 177 1.5E-20 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 SUPERFAMILY SSF52374 4 233 4.28E-145 T 28-03-2018 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 SUPERFAMILY SSF52374 433 687 4.28E-145 T 28-03-2018 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 575 585 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 504 522 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 542 564 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 241 8.9E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 229 420 9.8E-64 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 SUPERFAMILY SSF50677 233 431 1.44E-48 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 590 1.0E-9 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 637 677 7.3E-6 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 881 22.366 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Gene3D G3DSA:1.10.730.10 667 819 1.1E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 880 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 Pfam PF08264 Anticodon-binding domain of tRNA 720 845 1.0E-19 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 hmeg3_RS20480 e28fc0508b48434a797d24cb15096b89 881 SUPERFAMILY SSF47323 681 880 2.99E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 Gene3D G3DSA:1.20.120.530 68 223 6.2E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 SUPERFAMILY SSF48008 77 209 9.42E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 Pfam PF07729 FCD domain 82 204 3.5E-19 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 SMART SM00895 81 205 2.0E-14 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 SMART SM00345 13 71 5.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 SUPERFAMILY SSF46785 3 95 1.08E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06710 e9c0da1cb57528139e53745d53d3913c 230 Gene3D G3DSA:1.10.10.10 1 67 3.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10765 02627045d326ccd51ee62211347d6c36 550 SUPERFAMILY SSF51905 484 546 1.94E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10765 02627045d326ccd51ee62211347d6c36 550 SUPERFAMILY SSF51905 9 330 1.94E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10765 02627045d326ccd51ee62211347d6c36 550 Gene3D G3DSA:3.50.50.60 10 550 1.0E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10765 02627045d326ccd51ee62211347d6c36 550 Pfam PF05199 GMC oxidoreductase 419 539 5.3E-18 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS00720 0055b5a9fb61e7869e3dc58aadda95e6 376 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 22 272 2.1E-54 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 hmeg3_RS00720 0055b5a9fb61e7869e3dc58aadda95e6 376 Pfam PF04085 rod shape-determining protein MreC 128 271 9.0E-35 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 hmeg3_RS12450 7447222c1cd9a192f45d0c8d5c50f837 249 TIGRFAM TIGR02458 CbtA: cobalt transporter subunit CbtA (proposed) 6 246 6.2E-71 T 28-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative hmeg3_RS12450 7447222c1cd9a192f45d0c8d5c50f837 249 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 7 245 7.4E-57 T 28-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative hmeg3_RS14985 84ae3adaac8faee2c316bc8a01266c7f 231 Pfam PF01794 Ferric reductase like transmembrane component 55 168 4.6E-19 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain hmeg3_RS14985 84ae3adaac8faee2c316bc8a01266c7f 231 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 13 210 21.832 T 28-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 hmeg3_RS02350 3889b15c9655b914c5cd2749ec571726 143 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 115 1.7E-42 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 hmeg3_RS02350 3889b15c9655b914c5cd2749ec571726 143 SUPERFAMILY SSF52833 3 137 4.65E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02350 3889b15c9655b914c5cd2749ec571726 143 Pfam PF03960 ArsC family 6 114 4.5E-18 T 28-03-2018 IPR006660 Arsenate reductase-like hmeg3_RS02350 3889b15c9655b914c5cd2749ec571726 143 Gene3D G3DSA:3.40.30.10 1 140 1.6E-43 T 28-03-2018 hmeg3_RS10275 b820137981b6b410e61111f52df4203f 552 Gene3D G3DSA:1.20.1250.20 225 552 3.3E-33 T 28-03-2018 hmeg3_RS10275 b820137981b6b410e61111f52df4203f 552 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS10275 b820137981b6b410e61111f52df4203f 552 SUPERFAMILY SSF103473 453 546 7.67E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10275 b820137981b6b410e61111f52df4203f 552 SUPERFAMILY SSF103473 13 335 7.67E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10275 b820137981b6b410e61111f52df4203f 552 Pfam PF00083 Sugar (and other) transporter 19 226 8.5E-29 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 hmeg3_RS10275 b820137981b6b410e61111f52df4203f 552 Gene3D G3DSA:1.20.1250.20 9 224 3.4E-26 T 28-03-2018 hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 162 8.6E-43 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 SUPERFAMILY SSF48179 164 288 1.7E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 Gene3D G3DSA:3.40.50.720 1 175 2.3E-35 T 28-03-2018 hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 PIRSF PIRSF000103 1 288 1.7E-67 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 SUPERFAMILY SSF51735 1 162 1.75E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 Gene3D G3DSA:1.10.1040.10 176 288 7.6E-25 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS18150 e7d9439ebcf7057c1b059125c0b9a6e7 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 285 7.0E-33 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 SUPERFAMILY SSF51735 5 245 4.45E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 207 0.0045 T 28-03-2018 hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 Gene3D G3DSA:3.40.50.720 3 291 5.1E-52 T 28-03-2018 hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 Pfam PF00106 short chain dehydrogenase 5 192 3.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24035 8a45847823a8373f0d5e4ca60eaaa5b0 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04175 90daab1f291ab043dc5deca08a93bad1 427 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 79 5.2E-14 T 28-03-2018 hmeg3_RS04175 90daab1f291ab043dc5deca08a93bad1 427 Gene3D G3DSA:3.40.50.720 1 47 9.5E-5 T 28-03-2018 hmeg3_RS04175 90daab1f291ab043dc5deca08a93bad1 427 Gene3D G3DSA:3.90.660.20 48 418 2.1E-28 T 28-03-2018 hmeg3_RS04175 90daab1f291ab043dc5deca08a93bad1 427 SUPERFAMILY SSF51905 7 303 1.04E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS04175 90daab1f291ab043dc5deca08a93bad1 427 SUPERFAMILY SSF51905 385 414 1.04E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16450 f6374f55697b3b2d798a72f0fe2565e6 402 Gene3D G3DSA:1.20.1250.20 218 401 3.2E-17 T 28-03-2018 hmeg3_RS16450 f6374f55697b3b2d798a72f0fe2565e6 402 Gene3D G3DSA:1.20.1250.20 2 203 2.6E-14 T 28-03-2018 hmeg3_RS16450 f6374f55697b3b2d798a72f0fe2565e6 402 SUPERFAMILY SSF103473 21 391 1.57E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS16450 f6374f55697b3b2d798a72f0fe2565e6 402 Pfam PF07690 Major Facilitator Superfamily 227 390 1.9E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS16450 f6374f55697b3b2d798a72f0fe2565e6 402 Pfam PF07690 Major Facilitator Superfamily 25 202 3.3E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS17450 9d9bc435202ee5802c6be4a1e5f874c7 261 Gene3D G3DSA:3.40.50.300 1 251 6.4E-58 T 28-03-2018 hmeg3_RS17450 9d9bc435202ee5802c6be4a1e5f874c7 261 Pfam PF00005 ABC transporter 19 157 2.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS17450 9d9bc435202ee5802c6be4a1e5f874c7 261 SUPERFAMILY SSF52540 3 225 3.68E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17450 9d9bc435202ee5802c6be4a1e5f874c7 261 SMART SM00382 27 212 5.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17450 9d9bc435202ee5802c6be4a1e5f874c7 261 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 Pfam PF03466 LysR substrate binding domain 89 295 1.6E-39 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 Gene3D G3DSA:1.10.10.10 2 85 5.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 SUPERFAMILY SSF46785 1 113 6.54E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 Gene3D G3DSA:3.40.190.10 179 269 8.6E-18 T 28-03-2018 hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 Gene3D G3DSA:3.40.190.10 90 178 3.7E-19 T 28-03-2018 hmeg3_RS12930 13388ce9d052bc1f4074b0ab4e6417c0 308 SUPERFAMILY SSF53850 90 298 3.91E-38 T 28-03-2018 hmeg3_RS06930 6625f9c702a2eb8c8887c6a23f59e19f 477 Gene3D G3DSA:3.40.309.10 267 458 2.4E-67 T 28-03-2018 hmeg3_RS06930 6625f9c702a2eb8c8887c6a23f59e19f 477 Gene3D G3DSA:3.40.605.10 1 266 2.1E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS06930 6625f9c702a2eb8c8887c6a23f59e19f 477 Pfam PF00171 Aldehyde dehydrogenase family 13 472 2.5E-160 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS06930 6625f9c702a2eb8c8887c6a23f59e19f 477 SUPERFAMILY SSF53720 2 472 1.96E-163 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS19695 785c2772c2db9241cfb37453d58ba285 215 SUPERFAMILY SSF54593 1 102 9.19E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS19695 785c2772c2db9241cfb37453d58ba285 215 Gene3D G3DSA:3.10.180.10 1 105 1.4E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS19695 785c2772c2db9241cfb37453d58ba285 215 Pfam PF13468 Glyoxalase-like domain 7 177 2.4E-41 T 28-03-2018 IPR025870 Glyoxalase-like domain hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 Gene3D G3DSA:1.20.120.530 73 220 3.1E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 SMART SM00895 79 203 3.1E-21 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 3.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 SMART SM00345 11 69 1.7E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 SUPERFAMILY SSF48008 75 208 1.57E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 SUPERFAMILY SSF46785 4 73 1.18E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 Pfam PF07729 FCD domain 79 201 2.6E-27 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS12710 ed90490fcdbcadc2750b2e8c94a03ecf 234 Gene3D G3DSA:1.10.10.10 1 72 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23795 a29e3e9aaf74f0f9c4baf535cb75bbf1 341 Pfam PF01548 Transposase 7 143 1.1E-12 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 hmeg3_RS23795 a29e3e9aaf74f0f9c4baf535cb75bbf1 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 289 2.8E-26 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 hmeg3_RS14485 a29e3e9aaf74f0f9c4baf535cb75bbf1 341 Pfam PF01548 Transposase 7 143 1.1E-12 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 hmeg3_RS14485 a29e3e9aaf74f0f9c4baf535cb75bbf1 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 289 2.8E-26 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 hmeg3_RS02250 a29e3e9aaf74f0f9c4baf535cb75bbf1 341 Pfam PF01548 Transposase 7 143 1.1E-12 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 hmeg3_RS02250 a29e3e9aaf74f0f9c4baf535cb75bbf1 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 289 2.8E-26 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 hmeg3_RS10955 a8f0bc6f69d806538ac50567fc9735c1 262 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 4.2E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS10955 a8f0bc6f69d806538ac50567fc9735c1 262 Gene3D G3DSA:3.60.21.10 1 259 3.2E-43 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS10955 a8f0bc6f69d806538ac50567fc9735c1 262 SUPERFAMILY SSF56300 1 251 3.19E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS10955 a8f0bc6f69d806538ac50567fc9735c1 262 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 252 36.533 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 PIRSF PIRSF002122 3 156 6.8E-57 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.031 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.4E-65 T 28-03-2018 IPR023798 Ribosomal protein S7 domain hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 3.1E-63 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 SUPERFAMILY SSF47973 2 149 3.4E-61 T 28-03-2018 IPR023798 Ribosomal protein S7 domain hmeg3_RS22880 383ef028cab40e5102ae42640fba42fe 156 Gene3D G3DSA:1.10.455.10 6 156 6.1E-58 T 28-03-2018 IPR023798 Ribosomal protein S7 domain hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 SUPERFAMILY SSF50615 2 72 9.42E-24 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 465 2.4E-247 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 SUPERFAMILY SSF47917 350 465 3.66E-53 T 28-03-2018 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 Gene3D G3DSA:3.40.50.300 74 352 5.8E-88 T 28-03-2018 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 Gene3D G3DSA:1.10.1140.10 353 463 1.9E-44 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 SMART SM00382 140 332 0.0076 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 SUPERFAMILY SSF52540 75 352 2.57E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 9.2E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.169 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 347 2.5E-61 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02445 40e8dce0356e66d295255fae3be807a6 466 Gene3D G3DSA:2.40.10.170 1 73 1.7E-27 T 28-03-2018 hmeg3_RS20985 2eb5552f122be8ecd3eb0911c8d17ffc 277 Pfam PF05726 Pirin C-terminal cupin domain 192 265 4.0E-7 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 hmeg3_RS20985 2eb5552f122be8ecd3eb0911c8d17ffc 277 Gene3D G3DSA:2.60.120.10 1 266 6.4E-40 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS20985 2eb5552f122be8ecd3eb0911c8d17ffc 277 SUPERFAMILY SSF51182 7 262 3.08E-33 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS20985 2eb5552f122be8ecd3eb0911c8d17ffc 277 PIRSF PIRSF006232 2 275 2.8E-36 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 hmeg3_RS20985 2eb5552f122be8ecd3eb0911c8d17ffc 277 Pfam PF02678 Pirin 27 130 1.3E-15 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 75 3.1E-35 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.432 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 Gene3D G3DSA:1.10.1200.10 1 79 5.4E-27 T 28-03-2018 hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 Pfam PF00550 Phosphopantetheine attachment site 6 72 1.7E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 SUPERFAMILY SSF47336 1 77 7.33E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS16730 3044d47c6f78ca592d067e86e64cf793 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 2.0E-11 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 196 231 2.4E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 281 300 5.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 11 100 1.9E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 301 384 5.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 232 280 1.2E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Pfam PF13432 Tetratricopeptide repeat 126 179 0.0022 T 28-03-2018 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Pfam PF13432 Tetratricopeptide repeat 58 117 3.3E-9 T 28-03-2018 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Pfam PF13432 Tetratricopeptide repeat 227 291 1.8E-8 T 28-03-2018 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 142 195 2.5E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SUPERFAMILY SSF48452 131 355 1.23E-36 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:3.40.50.2000 481 652 4.3E-34 T 28-03-2018 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SUPERFAMILY SSF53756 384 626 1.95E-25 T 28-03-2018 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 257 291 0.02 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 53 86 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 223 256 7.0E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 121 154 42.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 155 188 17.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 189 222 1.5E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 292 325 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SMART SM00028 87 120 0.0019 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 562 624 6.1E-6 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 Gene3D G3DSA:1.25.40.10 101 141 8.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08370 0d1ccd36559775684d50663bc06a891a 654 SUPERFAMILY SSF48452 46 175 1.98E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15070 836053a433d1a920964fb3077112b807 158 SMART SM00347 41 137 1.3E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15070 836053a433d1a920964fb3077112b807 158 Pfam PF01047 MarR family 48 106 1.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15070 836053a433d1a920964fb3077112b807 158 Gene3D G3DSA:1.10.10.10 3 155 1.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15070 836053a433d1a920964fb3077112b807 158 SUPERFAMILY SSF46785 16 152 6.83E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 Gene3D G3DSA:3.30.950.10 145 260 2.0E-41 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 37 306 3.8E-81 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 36 257 35.805 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 37 236 2.4E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 PIRSF PIRSF005917 25 311 2.8E-100 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 114 125 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 SUPERFAMILY SSF53790 36 255 1.13E-75 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS00750 d43e907ae4bbf0751b1fea85da5b84fb 313 Gene3D G3DSA:3.40.1010.10 34 144 3.4E-37 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS22115 710a4c5d693e66d9123155b23abdc3ed 394 Pfam PF13458 Periplasmic binding protein 44 385 1.2E-50 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS22115 710a4c5d693e66d9123155b23abdc3ed 394 SUPERFAMILY SSF53822 44 389 9.76E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS22115 710a4c5d693e66d9123155b23abdc3ed 394 Gene3D G3DSA:3.40.50.2300 40 373 1.5E-54 T 28-03-2018 hmeg3_RS11485 3c503b22b4b810e8899a800306726cb5 217 Pfam PF04972 BON domain 78 145 1.8E-14 T 28-03-2018 IPR007055 BON domain hmeg3_RS11485 3c503b22b4b810e8899a800306726cb5 217 Pfam PF04972 BON domain 4 69 1.1E-13 T 28-03-2018 IPR007055 BON domain hmeg3_RS11485 3c503b22b4b810e8899a800306726cb5 217 Pfam PF04972 BON domain 152 215 3.6E-11 T 28-03-2018 IPR007055 BON domain hmeg3_RS11485 3c503b22b4b810e8899a800306726cb5 217 SMART SM00749 8 71 0.019 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS11485 3c503b22b4b810e8899a800306726cb5 217 SMART SM00749 154 217 62.0 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS11485 3c503b22b4b810e8899a800306726cb5 217 SMART SM00749 83 146 12.0 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS15870 ac87d6f50a3a8163f817ac689ae4fbc3 525 SUPERFAMILY SSF141868 275 515 3.4E-68 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15870 ac87d6f50a3a8163f817ac689ae4fbc3 525 Gene3D G3DSA:3.20.20.450 266 519 3.6E-75 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15870 ac87d6f50a3a8163f817ac689ae4fbc3 525 Pfam PF00563 EAL domain 274 502 1.9E-54 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15870 ac87d6f50a3a8163f817ac689ae4fbc3 525 SMART SM00052 267 508 2.4E-84 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15870 ac87d6f50a3a8163f817ac689ae4fbc3 525 Pfam PF12792 CSS motif domain associated with EAL 52 188 4.0E-13 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 SUPERFAMILY SSF50447 278 409 2.65E-29 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 22 545 52.09 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 SUPERFAMILY SSF52540 28 294 3.06E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Gene3D G3DSA:2.40.30.10 297 403 1.3E-24 T 28-03-2018 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 SUPERFAMILY SSF54980 410 485 5.04E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Pfam PF00009 Elongation factor Tu GTP binding domain 31 294 1.3E-50 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Gene3D G3DSA:3.30.70.870 406 482 1.7E-8 T 28-03-2018 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Gene3D G3DSA:3.40.50.300 24 296 7.5E-39 T 28-03-2018 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 PRINTS PR00315 GTP-binding elongation factor signature 103 113 1.4E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 PRINTS PR00315 GTP-binding elongation factor signature 33 46 1.4E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.4E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 PRINTS PR00315 GTP-binding elongation factor signature 119 130 1.4E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 PRINTS PR00315 GTP-binding elongation factor signature 83 91 1.4E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Pfam PF16658 Class II release factor RF3, C-terminal domain 404 532 1.4E-42 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 Pfam PF03144 Elongation factor Tu domain 2 331 395 4.6E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 33 174 7.9E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 76 91 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS09135 797687ba84a4723d94c50ee74efe728c 552 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 24 547 3.8E-241 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 hmeg3_RS05480 f1255472365c9a523c9ba136b3dbcc13 337 Gene3D G3DSA:3.30.460.20 13 147 3.1E-9 T 28-03-2018 hmeg3_RS05480 f1255472365c9a523c9ba136b3dbcc13 337 SUPERFAMILY SSF143865 5 270 6.15E-41 T 28-03-2018 hmeg3_RS05480 f1255472365c9a523c9ba136b3dbcc13 337 Gene3D G3DSA:1.20.58.340 150 270 2.3E-18 T 28-03-2018 hmeg3_RS05480 f1255472365c9a523c9ba136b3dbcc13 337 Pfam PF01544 CorA-like Mg2+ transporter protein 48 334 2.5E-58 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 hmeg3_RS05480 f1255472365c9a523c9ba136b3dbcc13 337 Gene3D G3DSA:1.20.58.340 271 337 2.2E-13 T 28-03-2018 hmeg3_RS05480 f1255472365c9a523c9ba136b3dbcc13 337 SUPERFAMILY SSF144083 272 334 3.92E-14 T 28-03-2018 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 SUPERFAMILY SSF52172 9 139 5.27E-32 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 SMART SM00421 153 210 1.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 Gene3D G3DSA:1.10.10.10 134 217 7.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 SUPERFAMILY SSF46894 147 216 8.84E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 Pfam PF00072 Response regulator receiver domain 11 123 4.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 SMART SM00448 9 122 1.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09295 8e82499b04e19a8f1e45bba5e8755198 217 Gene3D G3DSA:3.40.50.2300 8 133 2.3E-35 T 28-03-2018 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 Pfam PF00224 Pyruvate kinase, barrel domain 5 334 9.3E-117 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 470 1.8E-158 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 4.0E-27 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 SUPERFAMILY SSF50800 73 168 1.1E-26 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 Gene3D G3DSA:3.40.1380.20 319 471 2.1E-46 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 214 240 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 266 290 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 62 78 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 310 326 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 187 201 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 291 309 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 PRINTS PR01050 Pyruvate kinase family signature 241 265 2.5E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 SUPERFAMILY SSF51621 2 78 9.77E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 SUPERFAMILY SSF51621 168 340 9.77E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 SUPERFAMILY SSF52935 320 470 1.7E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 Gene3D G3DSA:3.20.20.60 5 166 8.5E-36 T 28-03-2018 hmeg3_RS17035 c7a52788e20e78dfdf99c122465af06b 472 Gene3D G3DSA:3.20.20.60 167 318 9.1E-59 T 28-03-2018 hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 Gene3D G3DSA:1.10.10.10 1 84 3.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 Pfam PF03466 LysR substrate binding domain 89 285 4.4E-28 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.5E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 Gene3D G3DSA:3.40.190.10 178 256 3.0E-10 T 28-03-2018 hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 SUPERFAMILY SSF46785 1 112 4.08E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 SUPERFAMILY SSF53850 90 288 5.61E-33 T 28-03-2018 hmeg3_RS15140 372e2af16ca40045e10009afe63e684a 305 Gene3D G3DSA:3.40.190.10 92 177 3.1E-13 T 28-03-2018 hmeg3_RS16085 2b11fe218388c9d7b8be5a919ee1ed84 216 SUPERFAMILY SSF161098 13 198 5.89E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS16085 2b11fe218388c9d7b8be5a919ee1ed84 216 Gene3D G3DSA:1.10.3720.10 2 216 4.0E-36 T 28-03-2018 hmeg3_RS16085 2b11fe218388c9d7b8be5a919ee1ed84 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 2.2E-28 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS16085 2b11fe218388c9d7b8be5a919ee1ed84 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 212 1.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 PIRSF PIRSF006337 16 611 6.8E-211 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Pfam PF11941 Domain of unknown function (DUF3459) 536 630 3.0E-10 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Gene3D G3DSA:2.60.40.1180 556 634 3.4E-15 T 28-03-2018 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 19 94 1.9E-4 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Gene3D G3DSA:2.60.40.10 16 118 3.6E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Gene3D G3DSA:3.20.20.80 119 472 8.5E-65 T 28-03-2018 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 SUPERFAMILY SSF51445 110 543 2.3E-102 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Pfam PF00128 Alpha amylase, catalytic domain 142 228 1.6E-15 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 30 588 4.5E-197 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 Gene3D G3DSA:1.10.10.760 473 511 1.4E-13 T 28-03-2018 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 SMART SM00642 131 483 9.6E-11 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11340 7a71075aff392ce84c19c532c224e349 636 SUPERFAMILY SSF81296 14 112 5.4E-15 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 9.0E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 SMART SM00382 33 232 3.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 Gene3D G3DSA:3.40.50.300 1 317 1.1E-73 T 28-03-2018 hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 SUPERFAMILY SSF52540 5 253 6.2E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 Pfam PF00005 ABC transporter 25 182 3.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS04595 1619dcf3b7db6ee3c4a87be2b461a021 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 315 3.7E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS06695 8353a091eff04b29703cf802c4c81260 437 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 42 422 7.4E-54 T 28-03-2018 IPR003776 YcaO-like domain hmeg3_RS06695 8353a091eff04b29703cf802c4c81260 437 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 91 411 4.4E-48 T 28-03-2018 IPR003776 YcaO-like domain hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 7.3E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.3E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.3E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.3E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.3E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.3E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 7.8E-55 T 28-03-2018 hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 Gene3D G3DSA:3.40.50.720 1 37 1.7E-5 T 28-03-2018 hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 Gene3D G3DSA:3.40.50.720 38 249 4.5E-59 T 28-03-2018 hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 SUPERFAMILY SSF51735 4 248 1.46E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS07555 c80d506605834e389a66d75220611b09 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 189 0.0013 T 28-03-2018 hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 SUPERFAMILY SSF53448 5 293 6.34E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 SUPERFAMILY SSF51182 189 480 4.34E-85 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 Gene3D G3DSA:2.60.120.10 349 459 1.8E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 Pfam PF00483 Nucleotidyl transferase 6 296 8.6E-67 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 Gene3D G3DSA:3.90.550.10 3 348 1.7E-94 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 Pfam PF01050 Mannose-6-phosphate isomerase 326 476 6.0E-72 T 28-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 hmeg3_RS17925 17f911cca49763afea50971929fa6bdf 481 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 4 480 1.6E-211 T 28-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 SUPERFAMILY SSF58104 317 598 3.01E-75 T 28-03-2018 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Gene3D G3DSA:1.10.287.950 405 598 1.1E-47 T 28-03-2018 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Gene3D G3DSA:1.10.287.950 283 404 7.6E-18 T 28-03-2018 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 409 563 2.1E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Pfam PF02743 Cache domain 41 257 1.1E-27 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Gene3D G3DSA:3.30.450.20 155 274 3.3E-22 T 28-03-2018 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 477 506 9.4E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 448 475 9.4E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 525 554 9.4E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 400 9.4E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 SMART SM00283 350 597 7.0E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 SUPERFAMILY SSF103190 112 173 6.8E-8 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Pfam PF00672 HAMP domain 299 344 3.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 SMART SM00304 295 349 5.8E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11190 b4723c90a0c86ed5e0898bcf1c76e6f6 598 Gene3D G3DSA:3.30.450.20 32 154 5.3E-18 T 28-03-2018 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 Pfam PF02416 mttA/Hcf106 family 4 43 1.4E-7 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 3 71 2.8E-20 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.6E-14 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.6E-14 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.6E-14 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 Gene3D G3DSA:1.20.5.1230 25 133 3.3E-4 T 28-03-2018 hmeg3_RS03535 15e41a79808e13fffb59c32823d7f503 166 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 119 15.981 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 hmeg3_RS01295 21e37f4f2bf9fac23e8c669693b85073 96 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 9.0E-18 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 hmeg3_RS01295 21e37f4f2bf9fac23e8c669693b85073 96 Pfam PF02426 Muconolactone delta-isomerase 1 90 9.5E-40 T 28-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 hmeg3_RS01295 21e37f4f2bf9fac23e8c669693b85073 96 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 2.1E-45 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 hmeg3_RS01295 21e37f4f2bf9fac23e8c669693b85073 96 PIRSF PIRSF001486 1 94 7.1E-47 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 hmeg3_RS01295 21e37f4f2bf9fac23e8c669693b85073 96 SUPERFAMILY SSF54909 1 95 6.97E-37 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 Gene3D G3DSA:3.90.1150.10 348 472 1.8E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 4.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 SMART SM00345 25 84 6.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 SUPERFAMILY SSF46785 19 88 8.39E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 SUPERFAMILY SSF53383 121 472 5.36E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 Pfam PF00155 Aminotransferase class I and II 155 467 4.7E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 Gene3D G3DSA:3.40.640.10 135 347 2.8E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS00840 5f8026812fceb2c7881e0f0b0f0a2818 472 Gene3D G3DSA:1.10.10.10 2 86 1.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 9 431 28.785 T 28-03-2018 IPR026593 Protein translocase subunit SecY hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 19 427 7.7E-133 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 Pfam PF00344 SecY translocase 73 415 3.0E-118 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PIRSF PIRSF004557 3 438 1.9E-125 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 Gene3D G3DSA:1.10.3370.10 11 437 2.6E-158 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 ProSitePatterns PS00756 Protein secY signature 2. 167 184 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 SUPERFAMILY SSF103491 17 422 1.44E-130 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 148 173 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 266 285 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 313 335 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 20 38 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 400 418 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 368 386 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 174 197 1.3E-94 T 28-03-2018 hmeg3_RS22760 f3aa3b5d7dc24dfa2668eaa219655d8b 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 1.3E-94 T 28-03-2018 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 241 270 2.8E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 318 345 2.8E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 347 376 2.8E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 424 2.8E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 Gene3D G3DSA:1.10.287.950 274 470 2.4E-44 T 28-03-2018 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 Gene3D G3DSA:1.10.287.950 155 273 3.9E-11 T 28-03-2018 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 280 435 1.3E-49 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 SMART SM00283 220 467 6.9E-81 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11420 a3c31e959d74aec365779d510dd37f9c 470 SUPERFAMILY SSF58104 195 468 5.67E-62 T 28-03-2018 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 SUPERFAMILY SSF47323 623 885 1.33E-61 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 612 1.0E-207 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 SUPERFAMILY SSF50677 192 343 1.24E-61 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Gene3D G3DSA:1.10.730.10 601 783 2.8E-54 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Gene3D G3DSA:1.10.287.380 864 934 1.2E-21 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Gene3D G3DSA:3.40.50.620 4 600 3.0E-135 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 SUPERFAMILY SSF52374 590 622 7.3E-138 T 28-03-2018 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 SUPERFAMILY SSF52374 342 552 7.3E-138 T 28-03-2018 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 SUPERFAMILY SSF52374 3 193 7.3E-138 T 28-03-2018 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 871 936 2.2E-19 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 PRINTS PR00986 Valyl-tRNA synthetase signature 37 48 8.1E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 8.1E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 PRINTS PR00986 Valyl-tRNA synthetase signature 456 477 8.1E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 PRINTS PR00986 Valyl-tRNA synthetase signature 347 360 8.1E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 PRINTS PR00986 Valyl-tRNA synthetase signature 487 505 8.1E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 918 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 936 15.752 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 SUPERFAMILY SSF46589 871 935 1.26E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 hmeg3_RS21595 6f730eca5022c09128b34a33fed4ca6d 936 Pfam PF08264 Anticodon-binding domain of tRNA 663 817 5.7E-38 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 hmeg3_RS10130 a3eafcfd93b1d2e1e1d0d850d18fb00f 319 SUPERFAMILY SSF141986 152 304 9.81E-45 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain hmeg3_RS10130 a3eafcfd93b1d2e1e1d0d850d18fb00f 319 SUPERFAMILY SSF52317 16 170 6.87E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10130 a3eafcfd93b1d2e1e1d0d850d18fb00f 319 PIRSF PIRSF028757 13 314 4.0E-79 T 28-03-2018 IPR003507 Peptidase family S66 hmeg3_RS10130 a3eafcfd93b1d2e1e1d0d850d18fb00f 319 Gene3D G3DSA:3.50.30.60 158 313 3.1E-46 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain hmeg3_RS10130 a3eafcfd93b1d2e1e1d0d850d18fb00f 319 Gene3D G3DSA:3.40.50.10740 8 157 2.0E-47 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain hmeg3_RS10130 a3eafcfd93b1d2e1e1d0d850d18fb00f 319 Pfam PF02016 LD-carboxypeptidase 22 299 9.7E-78 T 28-03-2018 IPR003507 Peptidase family S66 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Pfam PF04898 Glutamate synthase central domain 466 752 1.2E-110 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Gene3D G3DSA:2.160.20.60 1263 1557 6.4E-114 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Gene3D G3DSA:3.20.20.70 796 1261 3.4E-165 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 SUPERFAMILY SSF69336 1257 1543 3.01E-94 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Gene3D G3DSA:3.20.20.70 448 795 1.3E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 SUPERFAMILY SSF56235 16 441 4.63E-155 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 SUPERFAMILY SSF51395 461 922 8.55E-261 T 28-03-2018 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 SUPERFAMILY SSF51395 950 1244 8.55E-261 T 28-03-2018 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Pfam PF01645 Conserved region in glutamate synthase 813 1210 7.1E-155 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Pfam PF01493 GXGXG motif 1288 1474 2.9E-80 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Pfam PF00310 Glutamine amidotransferases class-II 16 439 5.8E-186 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain hmeg3_RS04280 1cabd192ba6c7754ddd589dcf8b5a5ca 1558 Gene3D G3DSA:3.60.20.10 16 447 1.8E-163 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 SUPERFAMILY SSF55781 10 205 9.6E-29 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 SUPERFAMILY SSF109604 413 519 2.29E-14 T 28-03-2018 hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 SUPERFAMILY SSF109604 203 283 2.29E-14 T 28-03-2018 hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 Pfam PF01966 HD domain 226 289 2.5E-7 T 28-03-2018 IPR006674 HD domain hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 Gene3D G3DSA:1.10.3210.10 207 538 6.4E-49 T 28-03-2018 hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 SMART SM00471 220 483 5.9E-8 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 SMART SM00065 27 203 3.0E-21 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 Pfam PF13487 HD domain 400 465 3.1E-23 T 28-03-2018 hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 Gene3D G3DSA:3.30.450.40 1 206 6.0E-27 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS22220 da1539daab3a1c4197fa5a28f173a83f 543 Pfam PF01590 GAF domain 30 193 8.2E-16 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS17625 f2a48ebfde34c7e302b3940a40e36372 346 SMART SM00267 142 324 1.4E-42 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17625 f2a48ebfde34c7e302b3940a40e36372 346 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 152 323 2.7E-38 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17625 f2a48ebfde34c7e302b3940a40e36372 346 Gene3D G3DSA:3.30.70.270 146 331 5.2E-50 T 28-03-2018 hmeg3_RS17625 f2a48ebfde34c7e302b3940a40e36372 346 SUPERFAMILY SSF55073 158 325 2.98E-40 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS17625 f2a48ebfde34c7e302b3940a40e36372 346 Pfam PF00990 Diguanylate cyclase, GGDEF domain 155 320 3.8E-36 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01815 025979bdfe89a551496b2e9867158521 237 Gene3D G3DSA:1.10.3720.10 3 236 6.0E-39 T 28-03-2018 hmeg3_RS01815 025979bdfe89a551496b2e9867158521 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 236 3.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS01815 025979bdfe89a551496b2e9867158521 237 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 130 2.2E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS01815 025979bdfe89a551496b2e9867158521 237 SUPERFAMILY SSF161098 25 222 5.76E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS22670 931e831560cefce87602d93a4353bb27 233 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 224 2.0E-45 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22670 931e831560cefce87602d93a4353bb27 233 TIGRFAM TIGR00035 asp_race: aspartate racemase 5 209 5.4E-35 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 hmeg3_RS22670 931e831560cefce87602d93a4353bb27 233 SUPERFAMILY SSF53681 6 113 3.11E-29 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22670 931e831560cefce87602d93a4353bb27 233 SUPERFAMILY SSF53681 119 226 4.25E-15 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22670 931e831560cefce87602d93a4353bb27 233 Gene3D G3DSA:3.40.50.1860 2 118 1.0E-29 T 28-03-2018 hmeg3_RS22670 931e831560cefce87602d93a4353bb27 233 Gene3D G3DSA:3.40.50.1860 119 214 3.6E-13 T 28-03-2018 hmeg3_RS15820 3dbe060797fa877444842f8e2e1bb5b5 433 SUPERFAMILY SSF52540 86 357 6.92E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15820 3dbe060797fa877444842f8e2e1bb5b5 433 Gene3D G3DSA:3.40.50.300 84 359 4.5E-74 T 28-03-2018 hmeg3_RS15820 3dbe060797fa877444842f8e2e1bb5b5 433 SMART SM00382 155 336 9.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15820 3dbe060797fa877444842f8e2e1bb5b5 433 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 18 430 2.4E-126 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS15820 3dbe060797fa877444842f8e2e1bb5b5 433 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 343 352 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS15820 3dbe060797fa877444842f8e2e1bb5b5 433 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 143 352 2.2E-70 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS17870 c7fa87bcccd2bcb829d5350491d98707 415 Gene3D G3DSA:1.50.10.10 13 414 4.0E-73 T 28-03-2018 hmeg3_RS17870 c7fa87bcccd2bcb829d5350491d98707 415 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 44 399 1.0E-106 T 28-03-2018 hmeg3_RS17870 c7fa87bcccd2bcb829d5350491d98707 415 SUPERFAMILY SSF48208 19 401 2.62E-111 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Gene3D G3DSA:3.40.30.10 103 197 9.1E-8 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Gene3D G3DSA:3.50.50.60 442 531 4.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 312 330 8.8E-40 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 8.8E-40 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 465 487 8.8E-40 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 439 455 8.8E-40 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 372 8.8E-40 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 313 321 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 347 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 350 374 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 402 418 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 441 462 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 475 493 9.2E-65 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 342 362 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Pfam PF13192 Thioredoxin domain 125 193 5.5E-7 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Gene3D G3DSA:3.50.50.60 199 338 3.7E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Gene3D G3DSA:3.40.30.10 1 94 5.7E-29 T 28-03-2018 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 514 5.5E-247 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 PIRSF PIRSF000238 1 518 1.9E-265 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 SUPERFAMILY SSF52833 104 197 8.96E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 501 2.5E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 Gene3D G3DSA:3.50.50.60 339 441 2.5E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 SUPERFAMILY SSF52833 1 101 3.13E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02775 0d0b45d764254a796732c6d5f8a21f42 531 SUPERFAMILY SSF51905 207 511 4.28E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00460 ffcb0fe608b79c29c1e2c562550cbee1 181 SUPERFAMILY SSF51182 14 179 4.01E-41 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS00460 ffcb0fe608b79c29c1e2c562550cbee1 181 Gene3D G3DSA:2.60.120.480 13 181 9.8E-43 T 28-03-2018 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 hmeg3_RS00460 ffcb0fe608b79c29c1e2c562550cbee1 181 Pfam PF04115 Ureidoglycolate lyase 13 174 1.5E-41 T 28-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 hmeg3_RS00460 ffcb0fe608b79c29c1e2c562550cbee1 181 PIRSF PIRSF017306 13 178 8.1E-24 T 28-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 Gene3D G3DSA:3.30.1490.20 138 200 7.0E-14 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 Pfam PF02222 ATP-grasp domain 136 301 1.0E-48 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 Gene3D G3DSA:3.40.50.20 22 107 1.3E-20 T 28-03-2018 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 SUPERFAMILY SSF56059 119 320 2.83E-54 T 28-03-2018 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 SUPERFAMILY SSF52440 16 114 5.32E-24 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 SUPERFAMILY SSF51246 324 398 1.1E-16 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 23 385 40.432 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 Gene3D G3DSA:3.30.470.20 201 399 9.1E-46 T 28-03-2018 hmeg3_RS20055 7e9fbaca21429c7d976bf3e2ab801e75 403 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 24 387 6.0E-115 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 SUPERFAMILY SSF52317 287 544 2.37E-80 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 Pfam PF06418 CTP synthase N-terminus 3 265 1.1E-123 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 Pfam PF00117 Glutamine amidotransferase class-I 300 539 9.7E-52 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 TIGRFAM TIGR00337 PyrG: CTP synthase 1 539 2.0E-236 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 Hamap MF_01227 CTP synthase [pyrG]. 2 544 50.362 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 Gene3D G3DSA:3.40.50.300 1 284 2.4E-127 T 28-03-2018 hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 Gene3D G3DSA:3.40.50.880 285 547 5.4E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS09265 d5ad9b74502c8e8b57d9a595b1cb18ec 556 SUPERFAMILY SSF52540 1 267 5.67E-120 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01850 4f90e500c66feaea4252e00f1e1741c1 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 3.8E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS01850 4f90e500c66feaea4252e00f1e1741c1 134 Gene3D G3DSA:3.10.180.10 3 134 2.3E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS01850 4f90e500c66feaea4252e00f1e1741c1 134 SUPERFAMILY SSF54593 2 127 6.33E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS00305 93a959c91c5323f8af50bc2866d49e54 280 Hamap MF_01384 Urease accessory protein UreD [ureD]. 7 264 29.521 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 hmeg3_RS00305 93a959c91c5323f8af50bc2866d49e54 280 Pfam PF01774 UreD urease accessory protein 50 253 1.5E-50 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 hmeg3_RS02550 64ee7dd561a2509e74a8182fb4b6dbfa 425 Gene3D G3DSA:1.20.1250.20 18 213 1.2E-22 T 28-03-2018 hmeg3_RS02550 64ee7dd561a2509e74a8182fb4b6dbfa 425 Gene3D G3DSA:1.20.1250.20 221 414 6.7E-24 T 28-03-2018 hmeg3_RS02550 64ee7dd561a2509e74a8182fb4b6dbfa 425 Pfam PF07690 Major Facilitator Superfamily 32 315 1.1E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS02550 64ee7dd561a2509e74a8182fb4b6dbfa 425 SUPERFAMILY SSF103473 12 413 1.96E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 SUPERFAMILY SSF53335 110 417 1.19E-71 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 296 308 1.3E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 198 212 1.3E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 237 1.3E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 399 416 1.3E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 346 362 1.3E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 Pfam PF01189 16S rRNA methyltransferase RsmB/F 219 414 2.5E-50 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 Gene3D G3DSA:3.30.70.1170 149 206 3.4E-18 T 28-03-2018 hmeg3_RS18345 56f67194700ea4d0c2eb8e633be1f251 418 Gene3D G3DSA:3.40.50.150 207 418 8.6E-59 T 28-03-2018 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 SUPERFAMILY SSF56003 319 749 2.79E-107 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Gene3D G3DSA:3.30.365.10 56 189 3.9E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 PIRSF PIRSF036389 2 748 4.1E-188 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Gene3D G3DSA:3.90.1170.50 190 333 1.9E-29 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Gene3D G3DSA:3.30.365.10 334 427 9.9E-22 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 SUPERFAMILY SSF56003 58 254 3.29E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 SMART SM01008 221 298 9.8E-18 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 322 611 1.1E-27 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 63 185 3.5E-25 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 613 694 8.7E-17 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Gene3D G3DSA:3.30.365.10 598 752 1.1E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS15610 92fb33124a9652082f6e7c86a0ef9410 752 Gene3D G3DSA:3.30.365.10 428 597 1.7E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS03010 e7b931b5c09e0e869e01ea367101887b 258 SMART SM00382 29 217 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03010 e7b931b5c09e0e869e01ea367101887b 258 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03010 e7b931b5c09e0e869e01ea367101887b 258 Pfam PF00005 ABC transporter 21 166 4.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03010 e7b931b5c09e0e869e01ea367101887b 258 Gene3D G3DSA:3.40.50.300 2 251 5.8E-59 T 28-03-2018 hmeg3_RS03010 e7b931b5c09e0e869e01ea367101887b 258 SUPERFAMILY SSF52540 3 234 4.28E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06760 15b4e0f27be26fca726c0afdd7842379 326 Pfam PF09084 NMT1/THI5 like 44 263 1.6E-20 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS06760 15b4e0f27be26fca726c0afdd7842379 326 SUPERFAMILY SSF53850 30 264 3.46E-37 T 28-03-2018 hmeg3_RS06760 15b4e0f27be26fca726c0afdd7842379 326 Gene3D G3DSA:3.40.190.10 131 265 1.5E-19 T 28-03-2018 hmeg3_RS06760 15b4e0f27be26fca726c0afdd7842379 326 Gene3D G3DSA:3.40.190.10 28 130 9.7E-15 T 28-03-2018 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 Gene3D G3DSA:3.30.420.10 1 156 9.5E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 112 146 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 SUPERFAMILY SSF53098 1 153 1.87E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 152 46.929 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 137 149 4.3E-34 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 82 98 4.3E-34 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 60 76 4.3E-34 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 4.3E-34 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 106 125 4.3E-34 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 2.2E-55 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS21640 20404561664f8ac5351c353879fc8e94 180 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 149 2.8E-53 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 hmeg3_RS01930 2c43854a0712bfedf895cf88e3a0fb55 680 Gene3D G3DSA:3.40.50.2000 173 342 1.3E-26 T 28-03-2018 hmeg3_RS01930 2c43854a0712bfedf895cf88e3a0fb55 680 Gene3D G3DSA:3.90.550.10 364 663 7.4E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01930 2c43854a0712bfedf895cf88e3a0fb55 680 Pfam PF00534 Glycosyl transferases group 1 185 306 9.1E-18 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 hmeg3_RS01930 2c43854a0712bfedf895cf88e3a0fb55 680 Pfam PF00535 Glycosyl transferase family 2 427 525 6.9E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS01930 2c43854a0712bfedf895cf88e3a0fb55 680 SUPERFAMILY SSF53448 424 620 4.22E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01930 2c43854a0712bfedf895cf88e3a0fb55 680 SUPERFAMILY SSF53756 12 361 8.24E-45 T 28-03-2018 hmeg3_RS24325 6c9cea220e56ef84c10a675db65c85cd 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 67 194 1.7E-5 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS24325 6c9cea220e56ef84c10a675db65c85cd 232 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 8 185 3.8E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS24325 6c9cea220e56ef84c10a675db65c85cd 232 SUPERFAMILY SSF56784 5 228 2.07E-33 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS24325 6c9cea220e56ef84c10a675db65c85cd 232 Gene3D G3DSA:3.40.50.1000 79 232 9.0E-18 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS24325 6c9cea220e56ef84c10a675db65c85cd 232 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 158 8.7E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS04735 d74ad88c750f936ce3f1632b8a91a33d 121 Gene3D G3DSA:2.60.300.12 16 121 3.4E-38 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 hmeg3_RS04735 d74ad88c750f936ce3f1632b8a91a33d 121 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 18 120 2.8E-38 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 hmeg3_RS04735 d74ad88c750f936ce3f1632b8a91a33d 121 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 121 36.662 T 28-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 hmeg3_RS04735 d74ad88c750f936ce3f1632b8a91a33d 121 SUPERFAMILY SSF89360 13 107 9.81E-31 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 hmeg3_RS04735 d74ad88c750f936ce3f1632b8a91a33d 121 Pfam PF01521 Iron-sulphur cluster biosynthesis 17 116 1.7E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 hmeg3_RS04735 d74ad88c750f936ce3f1632b8a91a33d 121 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 102 119 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 hmeg3_RS13345 6004d1329eac4f767ef1400b5b379813 223 Gene3D G3DSA:3.40.50.300 3 223 3.0E-54 T 28-03-2018 hmeg3_RS13345 6004d1329eac4f767ef1400b5b379813 223 SUPERFAMILY SSF52540 19 222 1.49E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13345 6004d1329eac4f767ef1400b5b379813 223 Pfam PF00005 ABC transporter 28 168 2.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS13345 6004d1329eac4f767ef1400b5b379813 223 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS13345 6004d1329eac4f767ef1400b5b379813 223 SMART SM00382 27 218 6.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS08150 6e439f5f5a23966bcb1cd67092a211f2 482 SMART SM00382 252 418 2.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS08150 6e439f5f5a23966bcb1cd67092a211f2 482 SUPERFAMILY SSF52540 249 443 1.19E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08150 6e439f5f5a23966bcb1cd67092a211f2 482 SMART SM00962 253 445 4.5E-51 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS08150 6e439f5f5a23966bcb1cd67092a211f2 482 Pfam PF00448 SRP54-type protein, GTPase domain 255 443 1.1E-32 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS08150 6e439f5f5a23966bcb1cd67092a211f2 482 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 341 2.8E-85 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 hmeg3_RS08150 6e439f5f5a23966bcb1cd67092a211f2 482 Gene3D G3DSA:3.40.50.300 250 446 4.6E-19 T 28-03-2018 hmeg3_RS17760 e9a901d6ddaba266b3c4f877c137233d 188 Pfam PF00692 dUTPase 82 184 3.7E-6 T 28-03-2018 IPR029054 dUTPase-like hmeg3_RS17760 e9a901d6ddaba266b3c4f877c137233d 188 SUPERFAMILY SSF51283 3 187 9.16E-53 T 28-03-2018 IPR029054 dUTPase-like hmeg3_RS17760 e9a901d6ddaba266b3c4f877c137233d 188 Gene3D G3DSA:2.70.40.10 1 161 6.9E-59 T 28-03-2018 hmeg3_RS17760 e9a901d6ddaba266b3c4f877c137233d 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.384 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 hmeg3_RS17760 e9a901d6ddaba266b3c4f877c137233d 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 187 5.6E-49 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 PRINTS PR00412 Epoxide hydrolase signature 47 62 8.1E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 PRINTS PR00412 Epoxide hydrolase signature 214 230 8.1E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 PRINTS PR00412 Epoxide hydrolase signature 27 45 8.1E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 Gene3D G3DSA:3.40.50.1820 1 273 1.4E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 Pfam PF00561 alpha/beta hydrolase fold 22 259 2.0E-31 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.5E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.5E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.5E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05355 ae2f8fc54cff94e0f5dca709ebcdbd1d 274 SUPERFAMILY SSF53474 2 272 1.92E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 SMART SM00863 169 218 2.8E-23 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Pfam PF02824 TGS domain 4 61 2.1E-7 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 5.0E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 5.0E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 5.0E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 5.0E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 5.0E-53 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 3.9E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Pfam PF03129 Anticodon binding domain 540 628 3.3E-19 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.407 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 SUPERFAMILY SSF55681 242 525 4.98E-100 T 28-03-2018 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Gene3D G3DSA:3.30.980.10 65 141 1.2E-24 T 28-03-2018 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 SUPERFAMILY SSF55186 64 240 5.76E-68 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 317 528 7.2E-43 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Gene3D G3DSA:3.30.930.10 220 530 3.2E-122 T 28-03-2018 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Gene3D G3DSA:3.10.20.30 1 64 1.1E-17 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Gene3D G3DSA:3.30.54.20 142 186 6.5E-19 T 28-03-2018 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 SUPERFAMILY SSF81271 2 61 1.47E-14 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 Gene3D G3DSA:3.40.50.800 531 635 5.7E-25 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 SUPERFAMILY SSF52954 529 632 1.66E-30 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS07750 b16ff5ce5bed1e714090810c9dc56e51 635 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 8.6E-219 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 hmeg3_RS07155 fc4793cddc7766a142d737e006389a63 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 109 5.2E-40 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 hmeg3_RS07155 fc4793cddc7766a142d737e006389a63 111 SUPERFAMILY SSF103481 10 108 8.76E-5 T 28-03-2018 hmeg3_RS07155 fc4793cddc7766a142d737e006389a63 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 108 24.925 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 hmeg3_RS03575 31905786ef8f278b8dd1068e218c664b 254 SUPERFAMILY SSF46626 195 218 1.83E-52 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03575 31905786ef8f278b8dd1068e218c664b 254 SUPERFAMILY SSF46626 18 166 1.83E-52 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS03575 31905786ef8f278b8dd1068e218c664b 254 Pfam PF02167 Cytochrome C1 family 34 252 5.6E-20 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 hmeg3_RS03575 31905786ef8f278b8dd1068e218c664b 254 Gene3D G3DSA:1.20.5.100 222 254 7.7E-12 T 28-03-2018 hmeg3_RS03575 31905786ef8f278b8dd1068e218c664b 254 Gene3D G3DSA:1.10.760.10 26 219 2.3E-58 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS14145 2e4c839f2d5a9bf8c1564cc32a6080c4 222 Gene3D G3DSA:1.20.1050.10 98 221 1.2E-22 T 28-03-2018 hmeg3_RS14145 2e4c839f2d5a9bf8c1564cc32a6080c4 222 SUPERFAMILY SSF52833 1 85 2.02E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS14145 2e4c839f2d5a9bf8c1564cc32a6080c4 222 Gene3D G3DSA:3.40.30.10 1 97 4.9E-24 T 28-03-2018 hmeg3_RS14145 2e4c839f2d5a9bf8c1564cc32a6080c4 222 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 74 1.2E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS14145 2e4c839f2d5a9bf8c1564cc32a6080c4 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 142 206 2.5E-9 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS14145 2e4c839f2d5a9bf8c1564cc32a6080c4 222 SUPERFAMILY SSF47616 83 212 5.99E-23 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS05930 1ed7ef6abeb20c7e11857e0ee2cca568 329 Pfam PF13460 NAD(P)H-binding 22 141 3.7E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05930 1ed7ef6abeb20c7e11857e0ee2cca568 329 SUPERFAMILY SSF51735 17 226 1.06E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05930 1ed7ef6abeb20c7e11857e0ee2cca568 329 Gene3D G3DSA:3.40.50.720 15 281 1.8E-19 T 28-03-2018 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 27 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Gene3D G3DSA:1.10.730.10 379 546 1.5E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 575 692 6.1E-40 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Gene3D G3DSA:3.40.50.620 258 378 4.3E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 SUPERFAMILY SSF52374 7 143 1.06E-92 T 28-03-2018 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 SUPERFAMILY SSF52374 178 392 1.06E-92 T 28-03-2018 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 SUPERFAMILY SSF57770 144 178 1.7E-11 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 SUPERFAMILY SSF50249 581 691 1.27E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Gene3D G3DSA:2.40.50.140 578 692 9.9E-28 T 28-03-2018 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Gene3D G3DSA:3.40.50.620 5 79 3.8E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Pfam PF01588 Putative tRNA binding domain 592 677 6.7E-22 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Pfam PF09334 tRNA synthetases class I (M) 10 402 1.0E-141 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 269 2.0E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 PRINTS PR01041 Methionyl-tRNA synthetase signature 390 401 2.0E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 PRINTS PR01041 Methionyl-tRNA synthetase signature 91 102 2.0E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 PRINTS PR01041 Methionyl-tRNA synthetase signature 43 57 2.0E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 PRINTS PR01041 Methionyl-tRNA synthetase signature 296 311 2.0E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 PRINTS PR01041 Methionyl-tRNA synthetase signature 11 24 2.0E-23 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Hamap MF_00098 Methionine--tRNA ligase [metG]. 7 555 38.051 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Gene3D G3DSA:2.170.220.10 168 257 6.5E-18 T 28-03-2018 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 SUPERFAMILY SSF47323 392 600 4.11E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 Gene3D G3DSA:2.20.28.20 144 167 5.8E-14 T 28-03-2018 hmeg3_RS15185 ab40b87e67aab88c61fdf158c0dbca6d 692 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 10 523 2.9E-159 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 Gene3D G3DSA:1.10.1660.10 1 58 1.8E-21 T 28-03-2018 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 Gene3D G3DSA:1.10.1660.10 59 139 1.8E-19 T 28-03-2018 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.8E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.8E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.8E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 3 129 4.2E-53 T 28-03-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 SUPERFAMILY SSF46955 4 126 1.17E-34 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 SMART SM00422 3 72 1.5E-29 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11825 b4f3780a1953d0b124c28a53bdade4f5 146 Pfam PF13411 MerR HTH family regulatory protein 4 69 6.4E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Pfam PF08447 PAS fold 767 853 1.3E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SUPERFAMILY SSF47384 879 947 1.57E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 994 1107 3.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Gene3D G3DSA:3.30.565.10 950 1108 4.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1092 1105 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1039 1053 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1068 1086 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1057 1067 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SMART SM00086 818 859 8.8E-5 T 28-03-2018 IPR001610 PAC motif hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SMART SM00387 993 1108 1.2E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Gene3D G3DSA:3.30.450.40 551 720 5.5E-19 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Gene3D G3DSA:1.10.510.10 28 295 5.0E-26 T 28-03-2018 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SUPERFAMILY SSF56112 73 308 9.65E-29 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Pfam PF00512 His Kinase A (phospho-acceptor) domain 883 948 4.8E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Gene3D G3DSA:3.30.450.20 721 875 3.7E-23 T 28-03-2018 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SUPERFAMILY SSF55874 943 1110 1.22E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SMART SM00388 881 951 1.5E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SMART SM00065 561 726 1.7E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Pfam PF01590 GAF domain 562 716 2.8E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Gene3D G3DSA:1.25.40.10 296 550 4.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SMART SM00220 31 306 2.8E-7 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 791 866 1.4E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Gene3D G3DSA:1.10.287.130 876 947 2.4E-6 T 28-03-2018 hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SUPERFAMILY SSF55781 546 632 3.49E-17 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SUPERFAMILY SSF55781 671 735 3.49E-17 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 SUPERFAMILY SSF55785 766 861 1.77E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05320 8383660ea02c43d9672adc3a12ade6e9 1114 Pfam PF00069 Protein kinase domain 79 294 3.4E-16 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 45.667 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 SUPERFAMILY SSF50104 126 271 1.81E-58 T 28-03-2018 IPR008991 Translation protein SH3-like domain hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 271 5.4E-125 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 SUPERFAMILY SSF50249 3 124 7.54E-46 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 Gene3D G3DSA:2.30.30.30 118 194 2.0E-30 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 Gene3D G3DSA:2.40.50.140 1 113 1.7E-43 T 28-03-2018 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 SMART SM01383 41 117 1.5E-43 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 41 116 1.3E-32 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 PIRSF PIRSF002158 13 274 8.1E-98 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 217 228 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 124 249 2.8E-54 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 Gene3D G3DSA:4.10.950.10 196 272 9.0E-34 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 hmeg3_RS22845 235d8d7f38eb174d7756dfd87bcdb7ce 274 SMART SM01382 123 251 1.1E-86 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 484 1.8E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 SMART SM00283 269 516 6.0E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 SUPERFAMILY SSF58104 244 517 6.8E-73 T 28-03-2018 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 178 2.3E-16 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 SMART SM00304 210 268 9.5E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 4.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 4.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 4.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 4.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 4.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 Gene3D G3DSA:1.10.287.950 31 323 3.0E-19 T 28-03-2018 hmeg3_RS22190 ff758f096a9536e4cf178bdf85bbccec 536 Gene3D G3DSA:1.10.287.950 324 520 4.3E-46 T 28-03-2018 hmeg3_RS06845 aa56e00223252b06c6f307d811e4caca 674 ProSitePatterns PS00018 EF-hand calcium-binding domain. 365 377 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site hmeg3_RS06845 aa56e00223252b06c6f307d811e4caca 674 Pfam PF07196 Flagellin hook IN motif 130 178 1.2E-7 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 hmeg3_RS06845 aa56e00223252b06c6f307d811e4caca 674 Pfam PF07196 Flagellin hook IN motif 369 404 5.2E-5 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 hmeg3_RS06845 aa56e00223252b06c6f307d811e4caca 674 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 433 657 1.2E-44 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 hmeg3_RS06945 53d363348b1d6396a048f232e5ebd46a 314 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 13 310 6.8E-114 T 28-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 hmeg3_RS06945 53d363348b1d6396a048f232e5ebd46a 314 SUPERFAMILY SSF53335 28 189 3.2E-8 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS06945 53d363348b1d6396a048f232e5ebd46a 314 SUPERFAMILY SSF53335 276 312 3.2E-8 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS06945 53d363348b1d6396a048f232e5ebd46a 314 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 13 312 1.6E-98 T 28-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent hmeg3_RS06945 53d363348b1d6396a048f232e5ebd46a 314 Gene3D G3DSA:3.40.50.150 17 313 3.9E-17 T 28-03-2018 hmeg3_RS06945 53d363348b1d6396a048f232e5ebd46a 314 PIRSF PIRSF018005 2 314 3.6E-110 T 28-03-2018 IPR017804 Methyltransferase EgtD-like hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 2.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 2.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 2.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 2.7E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Gene3D G3DSA:3.30.450.20 168 210 0.004 T 28-03-2018 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 271 3.5E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Pfam PF13188 PAS domain 101 148 1.6E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 426 4.4E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Gene3D G3DSA:1.10.287.130 211 266 8.6E-17 T 28-03-2018 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Gene3D G3DSA:3.30.565.10 267 428 1.6E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 SMART SM00388 205 272 2.0E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 SUPERFAMILY SSF55874 262 426 2.1E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 SMART SM00387 315 428 7.8E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 99 424 1.1E-118 T 28-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Pfam PF11808 Domain of unknown function (DUF3329) 12 93 1.4E-19 T 28-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 SUPERFAMILY SSF47384 193 271 2.55E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 SUPERFAMILY SSF55785 92 150 2.93E-7 T 28-03-2018 IPR000014 PAS domain hmeg3_RS06205 23b5d4d0dc90f4f0565a700eac35a2ef 439 Gene3D G3DSA:3.30.450.20 91 159 8.0E-6 T 28-03-2018 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Gene3D G3DSA:3.30.559.10 311 551 1.0E-79 T 28-03-2018 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 99 550 1.6E-188 T 28-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 SUPERFAMILY SSF51230 120 212 4.35E-24 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Gene3D G3DSA:3.90.1170.30 1 45 1.9E-9 T 28-03-2018 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Gene3D G3DSA:3.90.1170.30 46 162 2.8E-23 T 28-03-2018 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 SUPERFAMILY SSF47005 238 282 8.5E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Pfam PF00364 Biotin-requiring enzyme 121 191 4.9E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Pfam PF00364 Biotin-requiring enzyme 5 75 1.5E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Pfam PF02817 e3 binding domain 244 278 1.6E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Gene3D G3DSA:2.40.50.100 163 237 1.1E-7 T 28-03-2018 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 321 548 6.4E-80 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 SUPERFAMILY SSF51230 2 94 6.67E-24 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 Gene3D G3DSA:4.10.320.10 238 301 1.1E-17 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 143 172 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 hmeg3_RS17565 180d77db848a093ee5518df4a8568f8a 551 SUPERFAMILY SSF52777 310 550 1.11E-81 T 28-03-2018 hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 Gene3D G3DSA:3.30.70.790 71 156 2.4E-30 T 28-03-2018 hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 SMART SM00988 1 64 5.0E-20 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 PIRSF PIRSF036402 2 151 1.2E-45 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 138 22.774 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 SUPERFAMILY SSF69287 1 69 7.06E-15 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 SUPERFAMILY SSF69737 71 137 1.83E-19 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 Gene3D G3DSA:2.60.260.20 1 70 3.6E-23 T 28-03-2018 hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 Pfam PF02814 UreE urease accessory protein, N-terminal domain 15 64 1.1E-14 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal hmeg3_RS00285 6c6999b537d7cf71d68dfb95f9d6ca47 170 Pfam PF05194 UreE urease accessory protein, C-terminal domain 72 151 1.1E-26 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 hmeg3_RS08410 8beda81c14be0d3ee46074178d79317f 335 Pfam PF01384 Phosphate transporter family 25 324 4.8E-89 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 hmeg3_RS04810 55bd8cd0a1338ec6406a01538ab879b9 303 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 89 105 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site hmeg3_RS04810 55bd8cd0a1338ec6406a01538ab879b9 303 SUPERFAMILY SSF48576 10 296 9.66E-84 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS04810 55bd8cd0a1338ec6406a01538ab879b9 303 Pfam PF00348 Polyprenyl synthetase 39 272 7.8E-56 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 hmeg3_RS04810 55bd8cd0a1338ec6406a01538ab879b9 303 Gene3D G3DSA:1.10.600.10 2 303 2.0E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS04810 55bd8cd0a1338ec6406a01538ab879b9 303 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 340 1.3E-35 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 SUPERFAMILY SSF53756 3 356 3.14E-109 T 28-03-2018 hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 Gene3D G3DSA:3.40.50.2000 171 350 1.2E-33 T 28-03-2018 hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 142 1.1E-28 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 Gene3D G3DSA:3.40.50.2000 1 170 3.6E-37 T 28-03-2018 hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 352 1.6E-90 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS22010 1ddb05a84bc9fe70e23bde075e529eb0 358 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 356 31.92 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS00950 003e95e4f79b4b63e2633c0c97d24ade 482 Pfam PF02321 Outer membrane efflux protein 292 461 5.4E-29 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00950 003e95e4f79b4b63e2633c0c97d24ade 482 Pfam PF02321 Outer membrane efflux protein 70 264 1.9E-19 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00950 003e95e4f79b4b63e2633c0c97d24ade 482 SUPERFAMILY SSF56954 11 476 1.96E-109 T 28-03-2018 hmeg3_RS00950 003e95e4f79b4b63e2633c0c97d24ade 482 Gene3D G3DSA:1.20.1600.10 24 479 8.0E-103 T 28-03-2018 hmeg3_RS00950 003e95e4f79b4b63e2633c0c97d24ade 482 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 472 1.1E-122 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 148 1.1E-44 T 28-03-2018 hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 Gene3D G3DSA:3.40.50.300 194 442 4.3E-23 T 28-03-2018 hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 SUPERFAMILY SSF54211 10 175 3.45E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 Pfam PF01078 Magnesium chelatase, subunit ChlI 198 401 9.2E-97 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 SUPERFAMILY SSF52540 197 502 6.88E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 SMART SM00382 218 399 1.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 324 337 2.3E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 217 232 2.3E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 296 310 2.3E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 501 1.8E-186 T 28-03-2018 IPR004482 Mg chelatase-related protein hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 Gene3D G3DSA:3.30.230.10 2 193 5.0E-47 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS23025 65e7cb1d03847a83d0a1fcff899da30e 507 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 409 501 9.2E-30 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain hmeg3_RS24020 5402b53de85cd3a0c7ef976791c96b0c 263 Gene3D G3DSA:3.40.30.10 24 211 3.1E-14 T 28-03-2018 hmeg3_RS24020 5402b53de85cd3a0c7ef976791c96b0c 263 SUPERFAMILY SSF52833 57 167 6.09E-7 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS24020 5402b53de85cd3a0c7ef976791c96b0c 263 Pfam PF05988 Bacterial protein of unknown function (DUF899) 11 242 2.5E-92 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like hmeg3_RS13185 79438ecb90c840b61976c2fb32cb97a6 445 Gene3D G3DSA:1.20.1250.20 231 436 2.4E-17 T 28-03-2018 hmeg3_RS13185 79438ecb90c840b61976c2fb32cb97a6 445 Gene3D G3DSA:1.20.1250.20 1 224 3.4E-27 T 28-03-2018 hmeg3_RS13185 79438ecb90c840b61976c2fb32cb97a6 445 Pfam PF07690 Major Facilitator Superfamily 32 392 3.2E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS13185 79438ecb90c840b61976c2fb32cb97a6 445 SUPERFAMILY SSF103473 20 424 8.76E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 Gene3D G3DSA:1.10.1040.10 180 338 2.9E-58 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.822 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 1.7E-65 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 1.9E-132 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 SUPERFAMILY SSF48179 183 332 6.8E-72 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 PIRSF PIRSF000116 201 333 1.4E-15 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 PIRSF PIRSF000116 2 204 2.5E-46 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 Gene3D G3DSA:3.40.50.720 34 179 2.1E-54 T 28-03-2018 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.7E-71 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 hmeg3_RS13950 da17d8b8b3135f93afa2313a020bb908 338 SUPERFAMILY SSF51735 1 182 3.33E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS16790 266d703d87f6df92b9d8aeb40e9ea475 575 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 409 572 6.7E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16790 266d703d87f6df92b9d8aeb40e9ea475 575 Gene3D G3DSA:3.30.70.270 405 575 6.5E-53 T 28-03-2018 hmeg3_RS16790 266d703d87f6df92b9d8aeb40e9ea475 575 SMART SM00267 402 574 3.5E-62 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16790 266d703d87f6df92b9d8aeb40e9ea475 575 Pfam PF00990 Diguanylate cyclase, GGDEF domain 414 570 1.9E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16790 266d703d87f6df92b9d8aeb40e9ea475 575 SUPERFAMILY SSF158472 345 391 2.35E-5 T 28-03-2018 hmeg3_RS16790 266d703d87f6df92b9d8aeb40e9ea475 575 SUPERFAMILY SSF55073 418 573 1.02E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 4.6E-105 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 Gene3D G3DSA:3.30.70.250 143 184 1.6E-22 T 28-03-2018 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 SUPERFAMILY SSF55048 127 196 3.01E-18 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 305 3.3E-35 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 Pfam PF00698 Acyl transferase domain 6 274 1.2E-35 T 28-03-2018 IPR014043 Acyl transferase hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 PIRSF PIRSF000446 1 310 1.3E-112 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 Gene3D G3DSA:3.40.366.10 185 310 1.0E-29 T 28-03-2018 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 Gene3D G3DSA:3.40.366.10 3 142 1.4E-36 T 28-03-2018 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 SUPERFAMILY SSF52151 189 309 1.49E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS16740 0752ab4eccdba04e53e3c38f94160bc0 310 SUPERFAMILY SSF52151 4 121 1.49E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS13585 1103818e9d1698c7086260d3bbefa456 459 Gene3D G3DSA:3.30.70.270 284 459 5.1E-54 T 28-03-2018 hmeg3_RS13585 1103818e9d1698c7086260d3bbefa456 459 SMART SM00267 283 459 9.1E-63 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13585 1103818e9d1698c7086260d3bbefa456 459 SUPERFAMILY SSF55073 299 458 6.28E-47 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS13585 1103818e9d1698c7086260d3bbefa456 459 Pfam PF00990 Diguanylate cyclase, GGDEF domain 295 455 2.5E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13585 1103818e9d1698c7086260d3bbefa456 459 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 291 458 7.4E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 182 1.2E-4 T 28-03-2018 hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 SUPERFAMILY SSF51735 7 248 5.11E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 Gene3D G3DSA:3.40.50.720 1 250 1.1E-69 T 28-03-2018 hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18495 21d7dd49933eaf75cd72ae023047e87a 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 248 4.8E-58 T 28-03-2018 hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 Pfam PF06719 AraC-type transcriptional regulator N-terminus 19 168 7.5E-42 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 SUPERFAMILY SSF46689 234 284 3.48E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 SMART SM00342 197 280 3.3E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 Pfam PF12833 Helix-turn-helix domain 203 277 1.2E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 Gene3D G3DSA:1.10.10.60 153 235 1.1E-12 T 28-03-2018 hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 Gene3D G3DSA:1.10.10.60 236 290 3.0E-12 T 28-03-2018 hmeg3_RS01500 4774c7869d5aa420b130239df92d8ff7 302 SUPERFAMILY SSF46689 181 231 5.07E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 Gene3D G3DSA:3.40.50.1100 160 338 1.4E-24 T 28-03-2018 hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 321 5.6E-43 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 2 337 1.3E-192 T 28-03-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 Gene3D G3DSA:3.40.50.1100 50 159 5.4E-30 T 28-03-2018 hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 SUPERFAMILY SSF53686 5 334 2.74E-99 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 Hamap MF_00807 1-aminocyclopropane-1-carboxylate deaminase [acdS]. 2 338 71.903 T 28-03-2018 IPR020601 1-aminocyclopropane-1-carboxylate deaminase, bacterial GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 hmeg3_RS03845 7e7cab36c1bfa92534cb3bfa5a001f1c 338 PIRSF PIRSF006278 1 338 2.2E-122 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 SUPERFAMILY SSF54810 400 526 1.83E-48 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 208 526 4.4E-147 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Gene3D G3DSA:3.40.50.880 1 216 1.3E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 SUPERFAMILY SSF52317 1 232 6.88E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 PRINTS PR00097 Anthranilate synthase component II signature 76 87 1.4E-5 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.4E-5 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 PRINTS PR00097 Anthranilate synthase component II signature 172 185 1.4E-5 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Gene3D G3DSA:3.30.300.10 396 526 6.3E-53 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 3.2E-7 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 3.2E-7 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 172 185 3.2E-7 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Pfam PF00958 GMP synthase C terminal domain 438 525 4.4E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 526 55.713 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 200 1.1E-72 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Pfam PF00117 Glutamine amidotransferase class-I 7 194 2.3E-38 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 SUPERFAMILY SSF52402 192 414 7.72E-60 T 28-03-2018 hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Pfam PF02540 NAD synthase 211 287 6.4E-8 T 28-03-2018 IPR022310 NAD/GMP synthase hmeg3_RS10080 c2c6344395248791e88c2e8c460756c9 526 Gene3D G3DSA:3.40.50.620 217 395 6.3E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 135 7.6E-8 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 Gene3D G3DSA:3.30.390.10 1 178 2.1E-43 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 Gene3D G3DSA:3.20.20.120 179 425 2.0E-63 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 Pfam PF13378 Enolase C-terminal domain-like 201 416 1.1E-55 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 SUPERFAMILY SSF51604 183 424 1.11E-66 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 SUPERFAMILY SSF54826 3 138 1.43E-39 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 SMART SM00922 198 294 2.1E-25 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal hmeg3_RS21075 ee51aec605750f599e90542ac7a2e331 425 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 244 275 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PIRSF PIRSF500210 1 334 7.2E-129 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PIRSF PIRSF000904 1 334 1.2E-125 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 Gene3D G3DSA:3.40.190.80 201 334 5.3E-56 T 28-03-2018 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 4.3E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 4.3E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 308 333 4.3E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 206 233 4.3E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 180 203 4.3E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 149 172 4.3E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 194 2.6E-62 T 28-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 334 47.094 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 Gene3D G3DSA:3.30.540.10 9 200 1.1E-60 T 28-03-2018 hmeg3_RS18770 27598e810d06af1ac228cfc3e97ae201 334 SUPERFAMILY SSF56655 2 332 7.66E-119 T 28-03-2018 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 SUPERFAMILY SSF55073 421 581 4.97E-36 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 Pfam PF02743 Cache domain 41 331 5.6E-21 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 Gene3D G3DSA:3.30.450.20 206 348 1.7E-17 T 28-03-2018 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 Gene3D G3DSA:3.30.450.20 83 205 6.7E-16 T 28-03-2018 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 417 582 1.2E-36 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 SUPERFAMILY SSF103190 146 229 2.67E-5 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 SUPERFAMILY SSF158472 370 417 4.58E-8 T 28-03-2018 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 Pfam PF00672 HAMP domain 370 417 4.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 Gene3D G3DSA:3.30.70.270 406 583 3.0E-44 T 28-03-2018 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 SMART SM00267 406 586 2.4E-34 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 SMART SM00304 369 421 1.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS01390 60ffe592c4005dc24edff643788b2f15 591 Pfam PF00990 Diguanylate cyclase, GGDEF domain 418 581 6.5E-37 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 Gene3D G3DSA:3.40.800.10 1 298 6.3E-85 T 28-03-2018 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 TIGRFAM TIGR01229 rocF_arginase: arginase 6 299 1.8E-88 T 28-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 ProSitePatterns PS01053 Arginase family signature. 225 246 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 SUPERFAMILY SSF52768 5 297 8.28E-90 T 28-03-2018 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 Pfam PF00491 Arginase family 4 295 5.2E-80 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 PIRSF PIRSF036979 2 297 1.9E-33 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 PRINTS PR00116 Arginase signature 93 108 3.1E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 PRINTS PR00116 Arginase signature 120 147 3.1E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 PRINTS PR00116 Arginase signature 174 192 3.1E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 PRINTS PR00116 Arginase signature 257 271 3.1E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS14345 82637a4e92d82bcff1a835c7baa1e751 302 PRINTS PR00116 Arginase signature 222 251 3.1E-44 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 SUPERFAMILY SSF46458 1 142 1.3E-36 T 28-03-2018 IPR009050 Globin-like hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Gene3D G3DSA:1.10.490.10 1 159 5.1E-38 T 28-03-2018 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Pfam PF00042 Globin 7 103 8.1E-8 T 28-03-2018 IPR000971 Globin GO:0020037 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Hamap MF_01252 Flavohemoprotein [hmp]. 1 392 51.836 T 28-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 SUPERFAMILY SSF63380 151 253 5.62E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Gene3D G3DSA:3.40.50.80 254 392 2.3E-24 T 28-03-2018 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 SUPERFAMILY SSF52343 257 389 5.89E-34 T 28-03-2018 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Pfam PF00175 Oxidoreductase NAD-binding domain 264 368 1.2E-12 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Gene3D G3DSA:2.40.30.10 160 252 4.0E-28 T 28-03-2018 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 180 190 1.1E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 241 255 1.1E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 263 282 1.1E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 hmeg3_RS12260 99d932724d05075eac033bbed3a09136 393 Pfam PF00970 Oxidoreductase FAD-binding domain 158 253 8.5E-15 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 Gene3D G3DSA:3.40.50.300 200 366 1.0E-31 T 28-03-2018 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 Pfam PF00158 Sigma-54 interaction domain 194 360 1.1E-68 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 218 231 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 280 295 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 SMART SM00382 214 357 2.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 SUPERFAMILY SSF55781 25 170 1.48E-11 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 482 499 1.6E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 499 519 1.6E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 Gene3D G3DSA:1.10.8.60 367 475 1.9E-16 T 28-03-2018 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 Gene3D G3DSA:1.10.10.60 476 519 6.2E-13 T 28-03-2018 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 SUPERFAMILY SSF52540 193 430 3.2E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 Pfam PF02954 Bacterial regulatory protein, Fis family 479 511 7.7E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 SUPERFAMILY SSF46689 471 518 1.84E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 407 416 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site hmeg3_RS12255 5406750ac44ea28395a384f9e1d9601f 519 Gene3D G3DSA:3.30.450.40 6 199 7.8E-16 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS08385 bb8e61e18f6e4f1084d4dc8963539259 97 PIRSF PIRSF003135 1 96 2.1E-15 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 hmeg3_RS08385 bb8e61e18f6e4f1084d4dc8963539259 97 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 5.0E-30 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 hmeg3_RS08385 bb8e61e18f6e4f1084d4dc8963539259 97 SUPERFAMILY SSF50249 1 94 7.71E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08385 bb8e61e18f6e4f1084d4dc8963539259 97 Hamap MF_00720 Primosomal replication protein N [priB]. 1 96 22.495 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 hmeg3_RS12420 2e75a7f1fdae96a07ae2be6e42f6615d 392 SUPERFAMILY SSF111342 11 311 6.02E-75 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 hmeg3_RS12420 2e75a7f1fdae96a07ae2be6e42f6615d 392 Pfam PF01888 CbiD 19 296 4.1E-79 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 hmeg3_RS12420 2e75a7f1fdae96a07ae2be6e42f6615d 392 Gene3D G3DSA:3.30.2110.10 21 199 1.2E-58 T 28-03-2018 hmeg3_RS12420 2e75a7f1fdae96a07ae2be6e42f6615d 392 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 26 390 2.1E-55 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 hmeg3_RS12420 2e75a7f1fdae96a07ae2be6e42f6615d 392 PIRSF PIRSF026782 16 392 5.9E-103 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 hmeg3_RS12420 2e75a7f1fdae96a07ae2be6e42f6615d 392 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 19 392 26.92 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 hmeg3_RS00710 6680a290c55f3f6705c73c2939707be9 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 95 3.5E-17 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 hmeg3_RS00710 6680a290c55f3f6705c73c2939707be9 100 SUPERFAMILY SSF141000 6 98 5.1E-26 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 hmeg3_RS00710 6680a290c55f3f6705c73c2939707be9 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 100 1.5E-28 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 hmeg3_RS00710 6680a290c55f3f6705c73c2939707be9 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 100 21.299 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 hmeg3_RS19700 6eb66b27335247f44ddc1046de0bec3a 426 PIRSF PIRSF006066 1 426 4.3E-160 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS19700 6eb66b27335247f44ddc1046de0bec3a 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 416 3.1E-134 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit hmeg3_RS19700 6eb66b27335247f44ddc1046de0bec3a 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 8.4E-161 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS06410 bf0220778ca37530361df4a23c7b1d1b 347 Gene3D G3DSA:2.30.42.10 251 347 6.1E-20 T 28-03-2018 hmeg3_RS06410 bf0220778ca37530361df4a23c7b1d1b 347 SMART SM00228 267 334 5.6E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06410 bf0220778ca37530361df4a23c7b1d1b 347 Pfam PF13180 PDZ domain 255 343 1.3E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06410 bf0220778ca37530361df4a23c7b1d1b 347 SUPERFAMILY SSF50156 253 342 7.1E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 SUPERFAMILY SSF53448 1 247 1.71E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Gene3D G3DSA:2.160.10.10 310 433 8.2E-36 T 28-03-2018 hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 447 41.553 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 SUPERFAMILY SSF51161 250 431 4.55E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Gene3D G3DSA:2.160.10.10 235 309 2.8E-13 T 28-03-2018 hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Pfam PF12804 MobA-like NTP transferase domain 3 130 2.2E-22 T 28-03-2018 IPR025877 MobA-like NTP transferase hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 346 4.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 390 424 2.5E-7 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 Gene3D G3DSA:3.90.550.10 1 234 3.3E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01900 64c191d6db7dbe506a1b0e3da72d0340 452 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 449 7.2E-191 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 hmeg3_RS21770 db0f6f391fbcfadb2331dd1269d025f5 409 Pfam PF13719 zinc-ribbon domain 3 38 2.5E-13 T 28-03-2018 IPR011723 Zinc finger/thioredoxin putative hmeg3_RS21770 db0f6f391fbcfadb2331dd1269d025f5 409 Pfam PF11906 Protein of unknown function (DUF3426) 261 405 1.7E-37 T 28-03-2018 IPR021834 Protein of unknown function DUF3426 hmeg3_RS21770 db0f6f391fbcfadb2331dd1269d025f5 409 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 4 38 7.5E-14 T 28-03-2018 IPR011723 Zinc finger/thioredoxin putative hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 Pfam PF14698 Argininosuccinate lyase C-terminal 371 439 4.1E-26 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 Gene3D G3DSA:1.20.200.10 115 382 4.1E-99 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 1.0E-66 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 1.0E-66 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 1.0E-66 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 1.0E-66 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 1.0E-66 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 1.0E-66 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 SUPERFAMILY SSF48557 12 462 3.3E-152 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 Gene3D G3DSA:1.10.40.30 383 440 2.3E-27 T 28-03-2018 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 TIGRFAM TIGR00838 argH: argininosuccinate lyase 12 462 4.8E-185 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 Pfam PF00206 Lyase 15 308 8.9E-73 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 1.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 1.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 1.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 1.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 Gene3D G3DSA:1.10.275.10 10 114 8.2E-35 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS16935 a3c03412f92f298804057865bd56e3d3 463 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 461 43.054 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS21390 678452746a22b15f8589076cb046fc68 130 Gene3D G3DSA:3.30.420.140 1 130 4.9E-35 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 hmeg3_RS21390 678452746a22b15f8589076cb046fc68 130 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 2 127 20.215 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 hmeg3_RS21390 678452746a22b15f8589076cb046fc68 130 SMART SM00732 2 102 5.7E-23 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 hmeg3_RS21390 678452746a22b15f8589076cb046fc68 130 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 5 124 9.9E-28 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 hmeg3_RS21390 678452746a22b15f8589076cb046fc68 130 Pfam PF03652 Holliday junction resolvase 3 124 2.7E-33 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 hmeg3_RS21390 678452746a22b15f8589076cb046fc68 130 SUPERFAMILY SSF53098 3 125 2.73E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS15740 c84ba7461facbcc14d1c93a07ca24307 78 Pfam PF09392 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF 35 77 1.8E-14 T 28-03-2018 IPR021123 Type III secretion, needle-protein-like GO:0009405|GO:0015031 hmeg3_RS15740 c84ba7461facbcc14d1c93a07ca24307 78 SUPERFAMILY SSF140129 34 73 6.67E-13 T 28-03-2018 hmeg3_RS15740 c84ba7461facbcc14d1c93a07ca24307 78 TIGRFAM TIGR02105 III_needle: type III secretion apparatus needle protein 36 77 2.6E-11 T 28-03-2018 IPR011841 Type III secretion system, needle protein GO:0008565|GO:0009405|GO:0015031 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 SMART SM00342 304 387 1.4E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 Pfam PF13377 Periplasmic binding protein-like domain 115 271 1.7E-31 T 28-03-2018 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 Gene3D G3DSA:1.10.10.60 342 394 2.9E-13 T 28-03-2018 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 Gene3D G3DSA:1.10.10.60 278 341 3.0E-6 T 28-03-2018 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 Gene3D G3DSA:3.40.50.2300 113 276 8.6E-30 T 28-03-2018 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 SUPERFAMILY SSF53822 15 271 7.97E-38 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 SUPERFAMILY SSF46689 341 390 2.02E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 Pfam PF12833 Helix-turn-helix domain 311 388 2.3E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 SUPERFAMILY SSF46689 287 335 1.1E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS16500 2ccba595a80293a60763d6c8fa34fc2c 417 Gene3D G3DSA:3.40.50.2300 44 112 5.5E-6 T 28-03-2018 hmeg3_RS23235 eff4f02a90bcabf3f1f5bf575fd2e80d 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 1.1E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23235 eff4f02a90bcabf3f1f5bf575fd2e80d 221 SUPERFAMILY SSF161098 12 201 1.14E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23235 eff4f02a90bcabf3f1f5bf575fd2e80d 221 Gene3D G3DSA:1.10.3720.10 1 219 3.2E-48 T 28-03-2018 hmeg3_RS23235 eff4f02a90bcabf3f1f5bf575fd2e80d 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.1E-30 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 SUPERFAMILY SSF51905 12 232 2.1E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 Gene3D G3DSA:3.50.50.60 9 164 6.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 Gene3D G3DSA:3.50.50.60 356 429 0.15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 140 7.3E-7 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 14 36 7.3E-7 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 171 195 7.3E-7 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 Gene3D G3DSA:3.40.50.720 165 355 4.6E-12 T 28-03-2018 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 TIGRFAM TIGR04046 MSMEG_0569_nitr: flavin-dependent oxidoreductase, MSMEG_0569 family 13 413 3.7E-199 T 28-03-2018 IPR024000 Conserved hypothetical protein CHP04046, FMN-dependent hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 16 212 2.0E-27 T 28-03-2018 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 4.8E-5 T 28-03-2018 hmeg3_RS03685 6ebe16f4d1b3964f54c4762e820c5dd4 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 4.8E-5 T 28-03-2018 hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 53 113 1.6E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 Pfam PF07729 FCD domain 123 244 6.1E-24 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 SUPERFAMILY SSF46785 47 117 1.11E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 SUPERFAMILY SSF48008 118 251 1.07E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 Gene3D G3DSA:1.20.120.530 110 263 9.2E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 SMART SM00345 55 113 2.2E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 Gene3D G3DSA:1.10.10.10 10 109 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05985 50518d9c6b70e128b397cb9718a9e8ad 269 SMART SM00895 123 246 9.5E-21 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS13820 c277723d7f964f60f6f9a583483e93f8 336 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 324 2.0E-101 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B hmeg3_RS13820 c277723d7f964f60f6f9a583483e93f8 336 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 298 8.2E-90 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B hmeg3_RS13820 c277723d7f964f60f6f9a583483e93f8 336 SUPERFAMILY SSF50891 190 305 1.25E-12 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS13820 c277723d7f964f60f6f9a583483e93f8 336 SMART SM00797 23 315 3.5E-130 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 Gene3D G3DSA:3.40.50.720 1 246 4.0E-70 T 28-03-2018 hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 8.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 SUPERFAMILY SSF51735 4 245 8.25E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 Pfam PF00106 short chain dehydrogenase 5 196 4.4E-63 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS08645 5c126b9188d9471862a31ec9e8accb84 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 245 9.4E-120 T 28-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 hmeg3_RS03955 9386279b6c166dc8928d6297d578519f 273 Gene3D G3DSA:1.10.3720.10 2 259 1.0E-44 T 28-03-2018 hmeg3_RS03955 9386279b6c166dc8928d6297d578519f 273 SUPERFAMILY SSF161098 64 251 1.09E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03955 9386279b6c166dc8928d6297d578519f 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 270 2.1E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 SUPERFAMILY SSF51182 17 211 3.11E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 SMART SM00342 171 253 3.2E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 Pfam PF02311 AraC-like ligand binding domain 22 103 5.7E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 Gene3D G3DSA:1.10.10.60 154 207 6.4E-11 T 28-03-2018 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 Pfam PF12833 Helix-turn-helix domain 178 254 2.3E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 Gene3D G3DSA:2.60.120.10 1 99 7.3E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 Gene3D G3DSA:1.10.10.60 208 254 3.5E-11 T 28-03-2018 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 253 2.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 222 237 2.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 SUPERFAMILY SSF46689 208 252 1.93E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS14095 27417599a8cdde5170984c80b8d86955 254 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 249 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS09270 9712e79c99ba280fb3bbdc7e87313610 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 276 52.148 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 hmeg3_RS09270 9712e79c99ba280fb3bbdc7e87313610 284 Pfam PF00793 DAHP synthetase I family 7 274 8.2E-69 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 hmeg3_RS09270 9712e79c99ba280fb3bbdc7e87313610 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 275 2.4E-121 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 hmeg3_RS09270 9712e79c99ba280fb3bbdc7e87313610 284 Gene3D G3DSA:3.20.20.70 11 277 4.7E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS09270 9712e79c99ba280fb3bbdc7e87313610 284 SUPERFAMILY SSF51569 2 277 2.56E-101 T 28-03-2018 hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 Pfam PF12848 ABC transporter 224 309 3.4E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 Pfam PF00005 ABC transporter 18 184 6.4E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 Pfam PF00005 ABC transporter 335 469 7.0E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 Gene3D G3DSA:3.40.50.300 1 286 4.8E-51 T 28-03-2018 hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 Gene3D G3DSA:3.40.50.300 287 532 3.1E-45 T 28-03-2018 hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 SUPERFAMILY SSF52540 301 524 2.03E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 SMART SM00382 343 514 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 SMART SM00382 26 238 5.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10140 3330c396e5b032353546e1d3943612ee 532 SUPERFAMILY SSF52540 6 237 4.16E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 201 3.7E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 SUPERFAMILY SSF46894 140 207 3.33E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 Gene3D G3DSA:3.40.50.2300 9 134 4.6E-35 T 28-03-2018 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 SUPERFAMILY SSF52172 9 139 1.05E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 Gene3D G3DSA:1.10.10.10 135 213 3.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 Pfam PF00072 Response regulator receiver domain 12 122 4.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 SMART SM00448 10 123 8.6E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05395 11bd64f399fc7793eb391330936899f0 213 SMART SM00421 147 204 2.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05680 ee480b3b0cb390a2734ae8a61ecc6b27 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 313 5.1E-75 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS05680 ee480b3b0cb390a2734ae8a61ecc6b27 341 Gene3D G3DSA:3.40.190.10 154 307 0.27 T 28-03-2018 hmeg3_RS05680 ee480b3b0cb390a2734ae8a61ecc6b27 341 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 31 1.6E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal hmeg3_RS05680 ee480b3b0cb390a2734ae8a61ecc6b27 341 PIRSF PIRSF006470 7 338 5.4E-79 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS05680 ee480b3b0cb390a2734ae8a61ecc6b27 341 Gene3D G3DSA:3.40.190.10 16 124 0.069 T 28-03-2018 hmeg3_RS05680 ee480b3b0cb390a2734ae8a61ecc6b27 341 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 40 295 5.8E-70 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 SUPERFAMILY SSF52540 1 209 3.4E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 Gene3D G3DSA:1.10.8.60 142 221 4.0E-24 T 28-03-2018 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 SUPERFAMILY SSF48019 211 337 2.21E-30 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 215 334 4.0E-8 T 28-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 Pfam PF06144 DNA polymerase III, delta subunit 20 188 1.7E-21 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 336 3.8E-85 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 Gene3D G3DSA:1.20.272.10 222 339 8.5E-31 T 28-03-2018 hmeg3_RS20490 12195ad48eea4cc2b5350c77dd937e4d 339 Gene3D G3DSA:3.40.50.300 1 139 5.6E-19 T 28-03-2018 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 207 267 6.4E-19 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 SUPERFAMILY SSF81891 178 413 4.05E-53 T 28-03-2018 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 Gene3D G3DSA:3.30.460.10 21 176 8.4E-51 T 28-03-2018 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 SUPERFAMILY SSF81301 29 177 1.2E-39 T 28-03-2018 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 Pfam PF01743 Poly A polymerase head domain 55 180 3.3E-36 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 19 459 35.91 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 Pfam PF12626 Polymerase A arginine-rich C-terminus 321 454 1.2E-37 T 28-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 Gene3D G3DSA:1.10.3090.10 177 427 5.2E-42 T 28-03-2018 hmeg3_RS20295 3dbd4b0e3aa08ca5f51947f4cc54c511 475 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 25 423 2.8E-145 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 hmeg3_RS07525 9031ed967be19a416ce62c600c819870 274 SUPERFAMILY SSF53335 46 261 2.48E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS07525 9031ed967be19a416ce62c600c819870 274 Gene3D G3DSA:3.40.50.150 28 269 3.0E-22 T 28-03-2018 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 PIRSF PIRSF001365 7 304 1.0E-54 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 SMART SM01130 11 302 5.7E-73 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 Pfam PF00701 Dihydrodipicolinate synthetase family 13 300 1.8E-54 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 SUPERFAMILY SSF51569 13 302 8.16E-65 T 28-03-2018 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 11 302 43.216 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 Gene3D G3DSA:3.20.20.70 4 303 2.6E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS15575 482c0191cc481ac2d91774c2c4a2cd69 304 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 4 300 2.8E-136 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 hmeg3_RS15235 de62e2603a80ceec0e0a88155c0b9893 291 Hamap MF_01805 Segregation and condensation protein A [scpA]. 58 288 21.007 T 28-03-2018 IPR003768 Segregation and condensation protein A hmeg3_RS15235 de62e2603a80ceec0e0a88155c0b9893 291 Pfam PF02616 Segregation and condensation protein ScpA 75 286 1.6E-31 T 28-03-2018 IPR003768 Segregation and condensation protein A hmeg3_RS15235 de62e2603a80ceec0e0a88155c0b9893 291 Gene3D G3DSA:1.10.10.580 220 286 9.8E-14 T 28-03-2018 hmeg3_RS01290 897a079da296e99ff0102675fbf5fe84 303 Pfam PF00775 Dioxygenase 100 285 1.4E-59 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 hmeg3_RS01290 897a079da296e99ff0102675fbf5fe84 303 Pfam PF04444 Catechol dioxygenase N terminus 22 90 5.6E-25 T 28-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 hmeg3_RS01290 897a079da296e99ff0102675fbf5fe84 303 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 130 158 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 hmeg3_RS01290 897a079da296e99ff0102675fbf5fe84 303 SUPERFAMILY SSF49482 3 294 7.33E-93 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS01290 897a079da296e99ff0102675fbf5fe84 303 Gene3D G3DSA:2.60.130.10 1 303 1.0E-73 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 hmeg3_RS01290 897a079da296e99ff0102675fbf5fe84 303 TIGRFAM TIGR02439 catechol_proteo: catechol 1,2-dioxygenase 3 284 3.0E-137 T 28-03-2018 IPR012801 Catechol 1,2-dioxygenase, proteobacteria GO:0005506|GO:0018576|GO:0019614|GO:0055114 KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 PIRSF PIRSF000097 116 269 1.4E-21 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 PIRSF PIRSF000097 1 119 4.0E-18 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 SUPERFAMILY SSF51430 4 270 3.93E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 PRINTS PR00069 Aldo-keto reductase signature 128 145 9.1E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 PRINTS PR00069 Aldo-keto reductase signature 202 226 9.1E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 PRINTS PR00069 Aldo-keto reductase signature 98 116 9.1E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 PRINTS PR00069 Aldo-keto reductase signature 42 66 9.1E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 Gene3D G3DSA:3.20.20.100 4 280 1.7E-83 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS22295 4ac653582efb7da943eb03e423c4f537 280 Pfam PF00248 Aldo/keto reductase family 18 267 7.7E-56 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS18165 efcade8ce061b0d37bd0b71eedbdadc2 266 SUPERFAMILY SSF52540 4 228 3.79E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18165 efcade8ce061b0d37bd0b71eedbdadc2 266 Gene3D G3DSA:3.40.50.300 1 265 4.0E-58 T 28-03-2018 hmeg3_RS18165 efcade8ce061b0d37bd0b71eedbdadc2 266 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS18165 efcade8ce061b0d37bd0b71eedbdadc2 266 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 24 254 1.1E-99 T 28-03-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 hmeg3_RS18165 efcade8ce061b0d37bd0b71eedbdadc2 266 Pfam PF00005 ABC transporter 24 166 6.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS18165 efcade8ce061b0d37bd0b71eedbdadc2 266 SMART SM00382 33 216 1.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06225 891c3cbb354cb487a7004db5c1670d9a 270 SUPERFAMILY SSF47413 36 83 6.22E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS06225 891c3cbb354cb487a7004db5c1670d9a 270 SMART SM00530 16 85 3.3E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS06225 891c3cbb354cb487a7004db5c1670d9a 270 Gene3D G3DSA:1.10.260.40 3 102 8.7E-15 T 28-03-2018 hmeg3_RS06225 891c3cbb354cb487a7004db5c1670d9a 270 Pfam PF13560 Helix-turn-helix domain 12 90 2.4E-16 T 28-03-2018 hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 SUPERFAMILY SSF51735 2 231 7.93E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 Pfam PF00106 short chain dehydrogenase 2 187 7.0E-53 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS18085 7c173399ae74b411b4001e4ae794fd70 249 Gene3D G3DSA:3.40.50.720 1 234 1.5E-58 T 28-03-2018 hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 SUPERFAMILY SSF55785 192 305 2.3E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 SUPERFAMILY SSF55073 331 488 3.06E-25 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 Pfam PF00563 EAL domain 502 736 3.5E-60 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 Pfam PF00990 Diguanylate cyclase, GGDEF domain 327 481 8.0E-23 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 SMART SM00052 496 741 1.7E-86 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 Gene3D G3DSA:3.30.450.20 191 321 3.1E-11 T 28-03-2018 hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 SMART SM00267 312 486 8.1E-22 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 Gene3D G3DSA:3.30.70.270 323 494 5.2E-35 T 28-03-2018 hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 SUPERFAMILY SSF141868 501 747 1.11E-73 T 28-03-2018 IPR001633 EAL domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 325 486 1.1E-15 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00980 e7c4a762763710689aba08c02154f1ae 749 Gene3D G3DSA:3.20.20.450 495 749 3.0E-81 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 Gene3D G3DSA:3.10.105.10 294 499 8.9E-54 T 28-03-2018 hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 Gene3D G3DSA:3.90.76.10 44 147 3.2E-30 T 28-03-2018 hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 434 8.2E-96 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 PIRSF PIRSF002741 4 532 7.1E-139 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 SUPERFAMILY SSF53850 26 529 2.71E-138 T 28-03-2018 hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 77 99 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site hmeg3_RS23155 c5a6a5a877579d32c1c99558dfae888b 539 Gene3D G3DSA:3.40.190.10 148 293 3.9E-45 T 28-03-2018 hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 Gene3D G3DSA:3.40.190.10 173 250 2.0E-10 T 28-03-2018 hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 SUPERFAMILY SSF53850 89 285 1.52E-33 T 28-03-2018 hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 Gene3D G3DSA:3.40.190.10 88 172 1.4E-14 T 28-03-2018 hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 Gene3D G3DSA:1.10.10.10 1 87 4.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 Pfam PF03466 LysR substrate binding domain 88 280 9.9E-34 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01745 38b7539bf0043bcc477a1212b50cfd94 291 SUPERFAMILY SSF46785 1 82 8.94E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 Pfam PF03466 LysR substrate binding domain 88 293 6.2E-43 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 SUPERFAMILY SSF53850 90 298 2.72E-46 T 28-03-2018 hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 Gene3D G3DSA:1.10.10.10 3 84 3.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 Gene3D G3DSA:3.40.190.10 88 176 3.1E-14 T 28-03-2018 hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 SUPERFAMILY SSF46785 4 87 5.53E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 Gene3D G3DSA:3.40.190.10 177 265 1.2E-22 T 28-03-2018 hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02520 98afeaa83e3265b2e14fe62b3966e83d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 SUPERFAMILY SSF52518 125 552 7.07E-87 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 14 943 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Gene3D G3DSA:3.40.50.970 172 531 8.0E-85 T 28-03-2018 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Pfam PF02779 Transketolase, pyrimidine binding domain 600 797 5.2E-63 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 49 1.6E-16 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 PIRSF PIRSF000157 1 946 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 SMART SM00861 600 797 1.9E-57 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Gene3D G3DSA:1.10.287.1150 88 171 2.3E-21 T 28-03-2018 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 SUPERFAMILY SSF52518 583 803 9.81E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 802 944 1.7E-50 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Gene3D G3DSA:3.40.50.970 597 809 1.3E-56 T 28-03-2018 hmeg3_RS08780 b2e38f65a41ef276567eb57ed16662c7 954 Pfam PF00676 Dehydrogenase E1 component 220 521 1.4E-46 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 hmeg3_RS04760 2a57e814e6322f4bb90c2cc637a0f3fd 122 Gene3D G3DSA:3.40.50.2300 1 122 2.4E-36 T 28-03-2018 hmeg3_RS04760 2a57e814e6322f4bb90c2cc637a0f3fd 122 Pfam PF00072 Response regulator receiver domain 6 117 1.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS04760 2a57e814e6322f4bb90c2cc637a0f3fd 122 SMART SM00448 4 117 7.7E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS04760 2a57e814e6322f4bb90c2cc637a0f3fd 122 SUPERFAMILY SSF52172 4 120 4.7E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 Gene3D G3DSA:3.40.309.10 281 479 4.3E-72 T 28-03-2018 hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 Gene3D G3DSA:3.40.605.10 4 280 8.3E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 SUPERFAMILY SSF53720 14 496 3.93E-167 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 Pfam PF00171 Aldehyde dehydrogenase family 28 492 2.0E-167 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS19545 6cfb47fa2f0cf66ebdb0a3eacc0e1dd0 497 TIGRFAM TIGR03216 OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase 17 497 3.6E-270 T 28-03-2018 IPR017628 2-hydroxymuconic semialdehyde dehydrogenase GO:0016620|GO:0055114 hmeg3_RS24015 7b2dc3386bce916835f45abb5564a79b 223 Gene3D G3DSA:2.140.10.10 77 211 1.6E-18 T 28-03-2018 hmeg3_RS24015 7b2dc3386bce916835f45abb5564a79b 223 SUPERFAMILY SSF50969 32 218 7.46E-24 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like hmeg3_RS24015 7b2dc3386bce916835f45abb5564a79b 223 Gene3D G3DSA:2.140.10.10 9 76 0.016 T 28-03-2018 hmeg3_RS19615 99f11d7abc0bfdcf90fd8eb72c472d64 404 SUPERFAMILY SSF53822 33 403 1.28E-92 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS19615 99f11d7abc0bfdcf90fd8eb72c472d64 404 Gene3D G3DSA:3.40.50.2300 17 163 2.9E-21 T 28-03-2018 hmeg3_RS19615 99f11d7abc0bfdcf90fd8eb72c472d64 404 Pfam PF13458 Periplasmic binding protein 33 368 5.0E-91 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS19615 99f11d7abc0bfdcf90fd8eb72c472d64 404 Gene3D G3DSA:3.40.50.2300 164 313 2.2E-32 T 28-03-2018 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.0E-17 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 SMART SM00382 103 250 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Pfam PF00448 SRP54-type protein, GTPase domain 105 300 1.1E-69 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Gene3D G3DSA:1.10.260.30 332 437 1.8E-33 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 444 32.47 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 SMART SM00963 1 86 1.1E-29 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 SUPERFAMILY SSF47446 302 435 8.5E-42 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Gene3D G3DSA:1.20.120.140 1 90 1.9E-24 T 28-03-2018 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Gene3D G3DSA:3.40.50.300 103 213 2.0E-17 T 28-03-2018 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Gene3D G3DSA:1.20.120.140 214 314 1.1E-30 T 28-03-2018 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 434 1.6E-165 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 SUPERFAMILY SSF47364 1 89 3.14E-24 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 SUPERFAMILY SSF52540 97 302 6.16E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 SMART SM00962 104 300 2.6E-107 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 hmeg3_RS21835 22dab202bb15e21ff795ae5c094b995e 455 Pfam PF02978 Signal peptide binding domain 332 432 1.0E-30 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 SUPERFAMILY SSF111369 192 262 1.14E-6 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 Gene3D G3DSA:1.10.287.470 134 177 3.0E-11 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 Pfam PF13533 Biotin-lipoyl like 56 104 1.9E-10 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 Pfam PF13437 HlyD family secretion protein 213 333 4.3E-15 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 Gene3D G3DSA:2.40.50.100 204 372 1.7E-7 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 Gene3D G3DSA:2.40.50.100 55 133 2.7E-9 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 SUPERFAMILY SSF111369 115 178 2.75E-5 T 28-03-2018 hmeg3_RS12845 829f4af12f4de9a958f3362c0198a586 398 SUPERFAMILY SSF111369 55 110 1.44E-6 T 28-03-2018 hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 SUPERFAMILY SSF74982 3 127 9.29E-49 T 28-03-2018 IPR023620 Small protein B hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 3.0E-53 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 1.5E-54 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 Gene3D G3DSA:2.40.280.10 3 122 1.7E-46 T 28-03-2018 IPR023620 Small protein B hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 Hamap MF_00023 SsrA-binding protein [smpB]. 1 149 71.383 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 hmeg3_RS10060 0f2d4b0e77606609059d5d8cbae59eae 149 Pfam PF01668 SmpB protein 3 145 3.5E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 hmeg3_RS00570 57bfc549a2ef8761523eaf473041fbd0 309 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 213 229 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site hmeg3_RS00570 57bfc549a2ef8761523eaf473041fbd0 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 274 7.6E-44 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS00570 57bfc549a2ef8761523eaf473041fbd0 309 Gene3D G3DSA:3.40.50.720 106 275 3.3E-42 T 28-03-2018 hmeg3_RS00570 57bfc549a2ef8761523eaf473041fbd0 309 Gene3D G3DSA:3.40.50.720 3 105 1.1E-6 T 28-03-2018 hmeg3_RS00570 57bfc549a2ef8761523eaf473041fbd0 309 SUPERFAMILY SSF52283 30 123 4.59E-5 T 28-03-2018 hmeg3_RS00570 57bfc549a2ef8761523eaf473041fbd0 309 SUPERFAMILY SSF51735 95 274 7.45E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21315 198e31ba50b42d36dbe3fece4640ad01 112 Gene3D G3DSA:1.10.10.10 4 104 2.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21315 198e31ba50b42d36dbe3fece4640ad01 112 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 50 3.4E-14 T 28-03-2018 hmeg3_RS21315 198e31ba50b42d36dbe3fece4640ad01 112 SUPERFAMILY SSF46785 2 104 8.83E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21315 198e31ba50b42d36dbe3fece4640ad01 112 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 3 105 1.2E-46 T 28-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family hmeg3_RS00655 d4c245d17769606c1c8d176c5091f4c1 220 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 220 32.718 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS00655 d4c245d17769606c1c8d176c5091f4c1 220 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 191 3.0E-56 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS00655 d4c245d17769606c1c8d176c5091f4c1 220 SUPERFAMILY SSF53271 5 203 1.75E-44 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS00655 d4c245d17769606c1c8d176c5091f4c1 220 Pfam PF00156 Phosphoribosyl transferase domain 39 164 7.1E-15 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 hmeg3_RS00655 d4c245d17769606c1c8d176c5091f4c1 220 Gene3D G3DSA:3.40.50.2020 1 197 6.6E-46 T 28-03-2018 hmeg3_RS13465 62d15fce5172f50f3c150cdf51ee0c47 406 Pfam PF13458 Periplasmic binding protein 34 368 4.7E-86 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS13465 62d15fce5172f50f3c150cdf51ee0c47 406 Gene3D G3DSA:3.40.50.2300 164 314 2.2E-32 T 28-03-2018 hmeg3_RS13465 62d15fce5172f50f3c150cdf51ee0c47 406 SUPERFAMILY SSF53822 34 403 2.56E-87 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS13465 62d15fce5172f50f3c150cdf51ee0c47 406 Gene3D G3DSA:3.40.50.2300 32 163 1.4E-6 T 28-03-2018 hmeg3_RS05700 31eae149238001bba7406d91ac355d96 437 Pfam PF07005 Putative sugar-binding N-terminal domain 6 246 6.2E-49 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain hmeg3_RS05700 31eae149238001bba7406d91ac355d96 437 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 276 429 5.6E-30 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain hmeg3_RS05700 31eae149238001bba7406d91ac355d96 437 Gene3D G3DSA:3.40.50.10840 5 254 5.4E-50 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain hmeg3_RS05700 31eae149238001bba7406d91ac355d96 437 SUPERFAMILY SSF142764 6 433 1.31E-85 T 28-03-2018 hmeg3_RS01175 fa6c6dcb4fcf508a0ef2bdf2ec712d07 258 Gene3D G3DSA:3.40.50.300 2 258 4.5E-52 T 28-03-2018 hmeg3_RS01175 fa6c6dcb4fcf508a0ef2bdf2ec712d07 258 SUPERFAMILY SSF52540 12 253 4.02E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01175 fa6c6dcb4fcf508a0ef2bdf2ec712d07 258 Pfam PF00005 ABC transporter 30 183 1.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01175 fa6c6dcb4fcf508a0ef2bdf2ec712d07 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 253 2.4E-8 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS01175 fa6c6dcb4fcf508a0ef2bdf2ec712d07 258 SMART SM00382 37 230 6.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 185 205 2.2E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 2.2E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 2.2E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 2.2E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 2.2E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 SMART SM00283 266 513 2.8E-102 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 7.1E-57 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 Pfam PF17200 Single Cache domain 2 34 185 4.0E-39 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 Gene3D G3DSA:1.10.287.950 223 317 9.9E-13 T 28-03-2018 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 SMART SM01049 31 125 9.5E-39 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 SUPERFAMILY SSF58104 234 513 2.22E-74 T 28-03-2018 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 Gene3D G3DSA:1.10.287.950 318 517 4.0E-53 T 28-03-2018 hmeg3_RS09870 723f8aade77cc8d3a9f77f66bad655e5 589 Gene3D G3DSA:3.30.450.20 22 194 1.7E-46 T 28-03-2018 hmeg3_RS03235 9bb2b5e4cfa50e8c9221bd2340d08fd8 157 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 15 157 2.5E-55 T 28-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 hmeg3_RS03235 9bb2b5e4cfa50e8c9221bd2340d08fd8 157 Pfam PF01467 Cytidylyltransferase-like 27 121 3.1E-14 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 hmeg3_RS03235 9bb2b5e4cfa50e8c9221bd2340d08fd8 157 Gene3D G3DSA:3.40.50.620 23 146 4.3E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS03235 9bb2b5e4cfa50e8c9221bd2340d08fd8 157 SUPERFAMILY SSF52374 24 151 9.6E-21 T 28-03-2018 hmeg3_RS03235 9bb2b5e4cfa50e8c9221bd2340d08fd8 157 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 25 89 2.6E-11 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 hmeg3_RS19570 64064bf4bdf1f21bd5fedd9f77b053d8 261 Gene3D G3DSA:3.90.850.10 1 261 4.1E-38 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS19570 64064bf4bdf1f21bd5fedd9f77b053d8 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 101 255 3.2E-9 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS19570 64064bf4bdf1f21bd5fedd9f77b053d8 261 SUPERFAMILY SSF56529 1 256 7.94E-59 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 197 228 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 131 1.2E-31 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 Gene3D G3DSA:3.20.20.120 136 382 2.5E-58 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 SUPERFAMILY SSF51604 119 373 3.54E-65 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 8 375 5.7E-171 T 28-03-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 SUPERFAMILY SSF54826 8 132 4.13E-33 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 106 131 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 Gene3D G3DSA:3.30.390.10 3 135 3.6E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 SMART SM00922 149 247 8.6E-16 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal hmeg3_RS01300 980c36cd1a9b36369dd9bcdbc1207865 384 Pfam PF13378 Enolase C-terminal domain-like 154 367 1.0E-49 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 Pfam PF05746 DALR anticodon binding domain 595 696 1.1E-8 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 701 1.2E-195 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 SUPERFAMILY SSF109604 352 504 3.4E-19 T 28-03-2018 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 Gene3D G3DSA:1.10.3210.10 338 520 1.3E-4 T 28-03-2018 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 564 1.8E-190 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 Gene3D G3DSA:1.10.730.10 588 700 1.1E-11 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 701 23.83 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 SMART SM00836 598 701 0.0019 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 407 426 9.7E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 51 63 9.7E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 331 347 9.7E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 259 274 9.7E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS19855 8dfe918d5f5eb453838899137adfb07e 703 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 9.7E-33 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 hmeg3_RS15855 820312cfd77bafe0770d00afa3c8e12f 167 Pfam PF01464 Transglycosylase SLT domain 34 146 2.1E-28 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 hmeg3_RS15855 820312cfd77bafe0770d00afa3c8e12f 167 Gene3D G3DSA:1.10.530.10 21 160 1.4E-25 T 28-03-2018 hmeg3_RS15855 820312cfd77bafe0770d00afa3c8e12f 167 SUPERFAMILY SSF53955 25 155 7.1E-34 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 Gene3D G3DSA:1.10.10.10 124 217 4.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 Gene3D G3DSA:3.40.50.2300 1 123 4.4E-33 T 28-03-2018 hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 SMART SM00448 1 112 2.2E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 Pfam PF00072 Response regulator receiver domain 3 112 1.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 6.5E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 SUPERFAMILY SSF52172 1 132 9.82E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 SMART SM00862 145 216 6.3E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02020 06de46030e451ed2ce81e3e0514f2c8f 218 SUPERFAMILY SSF46894 118 215 2.18E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Gene3D G3DSA:3.30.70.1430 40 142 5.6E-20 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82714 726 800 3.66E-5 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82693 40 135 9.42E-17 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Gene3D G3DSA:1.20.1640.10 842 1059 1.1E-30 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Gene3D G3DSA:1.20.1640.10 281 496 7.2E-38 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 9.4E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Gene3D G3DSA:3.30.2090.10 184 265 6.8E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82693 137 182 6.28E-17 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82693 268 324 6.28E-17 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Gene3D G3DSA:3.30.70.1430 565 675 1.8E-12 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Gene3D G3DSA:3.30.2090.10 724 827 1.1E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82866 824 1048 7.98E-47 T 28-03-2018 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82714 185 266 2.35E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 Pfam PF00873 AcrB/AcrD/AcrF family 3 1045 3.2E-206 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00940 824bb9121707c9dbd2b04c8cd45d12c5 1080 SUPERFAMILY SSF82866 290 490 5.62E-41 T 28-03-2018 hmeg3_RS19610 367a41e36790c3830b274af67b731c3a 265 Pfam PF13490 Putative zinc-finger 5 37 9.7E-10 T 28-03-2018 IPR027383 Putative zinc-finger hmeg3_RS10730 b00991d7efca6131e9a292322cb5f136 159 Pfam PF13103 TonB C terminal 49 124 1.1E-4 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 hmeg3_RS10730 b00991d7efca6131e9a292322cb5f136 159 Gene3D G3DSA:3.30.1150.10 39 135 3.8E-10 T 28-03-2018 hmeg3_RS10730 b00991d7efca6131e9a292322cb5f136 159 SUPERFAMILY SSF74653 43 142 1.2E-8 T 28-03-2018 hmeg3_RS23875 24979a2c882a0268035410f7f44dc950 343 SUPERFAMILY SSF53686 25 338 3.27E-86 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS23875 24979a2c882a0268035410f7f44dc950 343 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 63 76 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 hmeg3_RS23875 24979a2c882a0268035410f7f44dc950 343 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 330 3.2E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS23875 24979a2c882a0268035410f7f44dc950 343 Gene3D G3DSA:3.40.50.1100 20 85 0.068 T 28-03-2018 hmeg3_RS23875 24979a2c882a0268035410f7f44dc950 343 Gene3D G3DSA:3.40.50.1100 127 343 1.3E-37 T 28-03-2018 hmeg3_RS23875 24979a2c882a0268035410f7f44dc950 343 Gene3D G3DSA:3.40.50.1100 86 126 3.9E-22 T 28-03-2018 hmeg3_RS05525 506c72f485a8dd9b4c5ada8eac77379a 97 Pfam PF13239 2TM domain 15 93 9.4E-22 T 28-03-2018 IPR025698 2TM domain hmeg3_RS09380 2af8dd8b93309899cbd6c18ea35858d9 176 Pfam PF10634 Fe2+ transport protein 22 169 3.8E-71 T 28-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type hmeg3_RS09380 2af8dd8b93309899cbd6c18ea35858d9 176 PIRSF PIRSF017018 2 176 2.0E-81 T 28-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type hmeg3_RS03250 db10d4b0399226d3dae1fa1781a0541c 324 SUPERFAMILY SSF53822 33 285 5.42E-16 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS03250 db10d4b0399226d3dae1fa1781a0541c 324 Gene3D G3DSA:3.40.50.2300 153 287 3.1E-18 T 28-03-2018 hmeg3_RS03250 db10d4b0399226d3dae1fa1781a0541c 324 Gene3D G3DSA:3.40.50.2300 6 152 1.8E-18 T 28-03-2018 hmeg3_RS03250 db10d4b0399226d3dae1fa1781a0541c 324 Pfam PF04392 ABC transporter substrate binding protein 35 322 3.8E-99 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 Pfam PF01029 NusB family 18 137 3.6E-5 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 Gene3D G3DSA:3.30.70.1170 184 239 3.2E-14 T 28-03-2018 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 18 409 8.3E-91 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 Gene3D G3DSA:1.10.287.730 157 183 1.8E-12 T 28-03-2018 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 260 270 6.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 231 245 6.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 328 340 6.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 378 394 6.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 418 435 6.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 SUPERFAMILY SSF53335 153 435 1.52E-64 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 Pfam PF01189 16S rRNA methyltransferase RsmB/F 250 409 2.3E-44 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 SUPERFAMILY SSF48013 18 160 3.05E-16 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 Gene3D G3DSA:1.10.940.10 16 156 1.8E-20 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 Gene3D G3DSA:3.40.50.150 240 438 3.1E-44 T 28-03-2018 hmeg3_RS23060 5296bc76b69383d9664ff1597a745306 438 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 327 338 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 PRINTS PR00834 HtrA/DegQ protease family signature 190 202 1.2E-12 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 PRINTS PR00834 HtrA/DegQ protease family signature 311 328 1.2E-12 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 PRINTS PR00834 HtrA/DegQ protease family signature 289 306 1.2E-12 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 PRINTS PR00834 HtrA/DegQ protease family signature 213 233 1.2E-12 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 Gene3D G3DSA:2.40.10.10 46 240 4.9E-18 T 28-03-2018 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 Pfam PF13365 Trypsin-like peptidase domain 181 318 1.2E-21 T 28-03-2018 hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 SUPERFAMILY SSF50494 170 352 8.26E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan hmeg3_RS20820 320c7083af93c84972dfb43267907499 386 Gene3D G3DSA:2.40.10.10 248 359 1.1E-18 T 28-03-2018 hmeg3_RS07730 d994e12fcdbf85f58941a2a61dd3ea4a 405 Gene3D G3DSA:3.40.640.10 20 280 2.2E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS07730 d994e12fcdbf85f58941a2a61dd3ea4a 405 SUPERFAMILY SSF53383 10 378 6.82E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS07730 d994e12fcdbf85f58941a2a61dd3ea4a 405 Gene3D G3DSA:3.90.1150.10 281 402 2.1E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS07730 d994e12fcdbf85f58941a2a61dd3ea4a 405 Pfam PF00266 Aminotransferase class-V 13 341 3.1E-30 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS07730 d994e12fcdbf85f58941a2a61dd3ea4a 405 PIRSF PIRSF000524 7 399 2.6E-123 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 hmeg3_RS24530 e2b747018db96647c79b163df85c0088 264 Gene3D G3DSA:1.10.3720.10 7 256 4.9E-41 T 28-03-2018 hmeg3_RS24530 e2b747018db96647c79b163df85c0088 264 SUPERFAMILY SSF161098 8 253 1.11E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24530 e2b747018db96647c79b163df85c0088 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 254 1.9E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23430 6f5036a5c98011a9169bf86c0ae55fa6 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 277 1.0E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23430 6f5036a5c98011a9169bf86c0ae55fa6 303 SUPERFAMILY SSF161098 64 269 1.18E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23430 6f5036a5c98011a9169bf86c0ae55fa6 303 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 64 172 1.2E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS23430 6f5036a5c98011a9169bf86c0ae55fa6 303 Gene3D G3DSA:1.10.3720.10 25 283 1.1E-41 T 28-03-2018 hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 SMART SM00382 372 558 1.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 SUPERFAMILY SSF90123 25 329 1.44E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 Gene3D G3DSA:1.20.1560.10 7 335 5.6E-20 T 28-03-2018 hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 Pfam PF00664 ABC transporter transmembrane region 39 296 3.6E-7 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 SUPERFAMILY SSF52540 339 570 3.3E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 Pfam PF00005 ABC transporter 363 511 4.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 Gene3D G3DSA:3.40.50.300 342 571 1.4E-62 T 28-03-2018 hmeg3_RS07605 dc3020f5f4edb234f96aa012163660e2 571 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 SUPERFAMILY SSF54506 3 282 4.71E-54 T 28-03-2018 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 Gene3D G3DSA:3.10.310.10 126 270 1.1E-49 T 28-03-2018 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 Pfam PF01678 Diaminopimelate epimerase 161 274 9.3E-28 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 Pfam PF01678 Diaminopimelate epimerase 5 125 1.4E-33 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 281 1.1E-88 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 283 38.188 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 hmeg3_RS02860 d77617ace9154c5f74f02f4d9c174051 283 Gene3D G3DSA:3.10.310.10 1 125 1.4E-49 T 28-03-2018 hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 9.8E-60 T 28-03-2018 hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 Gene3D G3DSA:3.40.50.720 1 36 4.7E-7 T 28-03-2018 hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 Gene3D G3DSA:3.40.50.720 37 246 5.4E-60 T 28-03-2018 hmeg3_RS24040 634fc1accf19405708f5298ab1103e2a 246 SUPERFAMILY SSF51735 6 245 9.48E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00165 fbde4ea2d837e7a6569773a0fc2c35d4 348 Pfam PF00355 Rieske [2Fe-2S] domain 21 99 7.5E-15 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS00165 fbde4ea2d837e7a6569773a0fc2c35d4 348 SUPERFAMILY SSF55961 133 332 1.54E-44 T 28-03-2018 hmeg3_RS00165 fbde4ea2d837e7a6569773a0fc2c35d4 348 SUPERFAMILY SSF50022 11 125 3.93E-26 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS00165 fbde4ea2d837e7a6569773a0fc2c35d4 348 Gene3D G3DSA:3.90.380.10 124 338 5.7E-32 T 28-03-2018 hmeg3_RS00165 fbde4ea2d837e7a6569773a0fc2c35d4 348 Gene3D G3DSA:2.102.10.10 15 123 3.2E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS18350 80107c1a7d9881d153adb5d127466105 206 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 191 2.6E-71 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 hmeg3_RS18350 80107c1a7d9881d153adb5d127466105 206 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.978 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 hmeg3_RS18350 80107c1a7d9881d153adb5d127466105 206 Gene3D G3DSA:3.40.50.170 2 205 1.3E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS18350 80107c1a7d9881d153adb5d127466105 206 Pfam PF00551 Formyl transferase 4 182 3.4E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS18350 80107c1a7d9881d153adb5d127466105 206 SUPERFAMILY SSF53328 4 199 1.96E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Gene3D G3DSA:2.40.50.100 1113 1168 0.016 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Pfam PF00623 RNA polymerase Rpb1, domain 2 406 485 1.1E-26 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 394 3.8E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Pfam PF05000 RNA polymerase Rpb1, domain 4 675 764 1.1E-17 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Gene3D G3DSA:2.40.40.20 346 488 6.6E-40 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 645 1.7E-22 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 8.6E-86 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Gene3D G3DSA:2.40.50.100 1014 1042 0.088 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 SMART SM00663 235 514 1.1E-173 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Gene3D G3DSA:2.40.50.100 908 1013 3.7E-30 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Gene3D G3DSA:2.40.50.100 1169 1215 1.1E-11 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Pfam PF04998 RNA polymerase Rpb1, domain 5 767 1318 1.1E-77 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Gene3D G3DSA:2.40.50.100 1043 1112 3.3E-12 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 13 1379 18.735 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 SUPERFAMILY SSF64484 16 945 0.0 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 SUPERFAMILY SSF64484 1136 1366 0.0 T 28-03-2018 hmeg3_RS22900 5ae070909c11719bf2c354c606494e10 1412 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1369 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 Gene3D G3DSA:1.10.390.10 267 464 7.8E-26 T 28-03-2018 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 Pfam PF05299 M61 glycyl aminopeptidase 279 394 3.4E-46 T 28-03-2018 IPR007963 Peptidase M61, catalytic domain hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 SUPERFAMILY SSF50156 483 574 4.34E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 Gene3D G3DSA:2.30.42.10 488 592 1.7E-8 T 28-03-2018 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 SMART SM00228 474 558 0.0049 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 Pfam PF13180 PDZ domain 492 567 6.3E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 PIRSF PIRSF016493 1 595 2.3E-215 T 28-03-2018 IPR024191 Peptidase M61 hmeg3_RS04290 e854aefb398ab7c9c64f7bb2ccdfdca0 597 SUPERFAMILY SSF55486 214 464 6.44E-10 T 28-03-2018 hmeg3_RS12365 b02815d16215e160adb24c9a67cbedf4 346 SUPERFAMILY SSF53383 3 328 2.62E-57 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS12365 b02815d16215e160adb24c9a67cbedf4 346 Pfam PF00155 Aminotransferase class I and II 60 279 9.0E-29 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS12365 b02815d16215e160adb24c9a67cbedf4 346 Gene3D G3DSA:3.40.640.10 42 228 3.0E-26 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS12365 b02815d16215e160adb24c9a67cbedf4 346 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 4 328 3.8E-104 T 28-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 hmeg3_RS12365 b02815d16215e160adb24c9a67cbedf4 346 Gene3D G3DSA:3.90.1150.10 229 340 1.3E-10 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12365 b02815d16215e160adb24c9a67cbedf4 346 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 194 207 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 8.4E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 252 261 8.4E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 8.4E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 287 8.4E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 Gene3D G3DSA:3.40.50.1370 1 143 7.0E-55 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 Gene3D G3DSA:3.40.50.1370 144 301 4.1E-52 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 300 73.906 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 120 134 2.5E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 216 226 2.5E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 278 289 2.5E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 47 61 2.5E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 80 93 2.5E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 299 4.8E-107 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 SUPERFAMILY SSF53671 2 299 8.45E-102 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 143 1.3E-48 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 hmeg3_RS06875 e84c962b1ca7a4b4e8211373bc88d606 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 297 4.3E-48 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 hmeg3_RS21650 720ae5e08e23496ed9bd2039afc09a58 77 Pfam PF02954 Bacterial regulatory protein, Fis family 37 74 7.2E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS21650 720ae5e08e23496ed9bd2039afc09a58 77 PIRSF PIRSF002097 1 77 1.7E-30 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 hmeg3_RS21650 720ae5e08e23496ed9bd2039afc09a58 77 Gene3D G3DSA:1.10.10.60 2 77 3.3E-18 T 28-03-2018 hmeg3_RS21650 720ae5e08e23496ed9bd2039afc09a58 77 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 40 57 3.2E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS21650 720ae5e08e23496ed9bd2039afc09a58 77 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 57 77 3.2E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS21650 720ae5e08e23496ed9bd2039afc09a58 77 SUPERFAMILY SSF46689 10 76 3.44E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS21790 1bf89ab0091960efc390ca17e5b07649 239 Pfam PF07382 Histone H1-like nucleoprotein HC2 102 235 5.4E-11 T 28-03-2018 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 hmeg3_RS21790 1bf89ab0091960efc390ca17e5b07649 239 PRINTS PR00624 Histone H5 signature 23 37 2.2E-6 T 28-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 hmeg3_RS21790 1bf89ab0091960efc390ca17e5b07649 239 PRINTS PR00624 Histone H5 signature 54 71 2.2E-6 T 28-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 hmeg3_RS21790 1bf89ab0091960efc390ca17e5b07649 239 PRINTS PR00624 Histone H5 signature 76 95 2.2E-6 T 28-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Pfam PF07695 7TM diverse intracellular signalling 178 379 1.7E-35 T 28-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Gene3D G3DSA:3.30.565.10 493 662 4.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Gene3D G3DSA:1.20.120.160 798 920 8.4E-8 T 28-03-2018 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SMART SM00387 536 652 2.5E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Gene3D G3DSA:1.10.287.130 416 484 1.1E-8 T 28-03-2018 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Gene3D G3DSA:3.40.50.2300 673 793 2.1E-18 T 28-03-2018 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SMART SM00448 677 791 4.0E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SUPERFAMILY SSF47384 409 483 5.49E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Pfam PF07696 7TMR-DISM extracellular 2 33 155 1.0E-14 T 28-03-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SMART SM00388 426 489 7.8E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 536 648 3.3E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 611 629 5.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 649 5.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 592 5.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SUPERFAMILY SSF55874 529 675 1.96E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Pfam PF00072 Response regulator receiver domain 679 790 6.1E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SUPERFAMILY SSF52172 675 792 1.07E-16 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 Pfam PF00512 His Kinase A (phospho-acceptor) domain 426 485 3.3E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS10205 b273002c186481a4ac57b3097291ff92 925 SUPERFAMILY SSF47226 814 919 3.66E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS12740 05126441307305299a8d705889b08a10 130 Gene3D G3DSA:1.10.10.10 2 130 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12740 05126441307305299a8d705889b08a10 130 Pfam PF12802 MarR family 18 76 2.3E-10 T 28-03-2018 hmeg3_RS12740 05126441307305299a8d705889b08a10 130 SUPERFAMILY SSF46785 16 127 1.87E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12740 05126441307305299a8d705889b08a10 130 SMART SM00347 12 112 4.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS12740 05126441307305299a8d705889b08a10 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 4.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS12740 05126441307305299a8d705889b08a10 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 122 4.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS12740 05126441307305299a8d705889b08a10 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 68 4.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS24545 c31d747c0e7780d457cc9129f63d52f0 406 Gene3D G3DSA:3.30.9.10 78 325 7.2E-39 T 28-03-2018 hmeg3_RS24545 c31d747c0e7780d457cc9129f63d52f0 406 SUPERFAMILY SSF51905 18 238 1.08E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24545 c31d747c0e7780d457cc9129f63d52f0 406 SUPERFAMILY SSF51905 329 393 1.08E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24545 c31d747c0e7780d457cc9129f63d52f0 406 Gene3D G3DSA:3.50.50.60 2 77 9.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24545 c31d747c0e7780d457cc9129f63d52f0 406 SUPERFAMILY SSF54373 248 327 2.62E-7 T 28-03-2018 hmeg3_RS24545 c31d747c0e7780d457cc9129f63d52f0 406 Pfam PF01266 FAD dependent oxidoreductase 19 368 4.4E-63 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS09525 ec065b5e30a24e60ddeb0ac367165152 309 Gene3D G3DSA:1.10.3130.10 59 183 5.2E-39 T 28-03-2018 hmeg3_RS09525 ec065b5e30a24e60ddeb0ac367165152 309 Gene3D G3DSA:2.160.10.10 184 299 1.4E-25 T 28-03-2018 hmeg3_RS09525 ec065b5e30a24e60ddeb0ac367165152 309 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 249 283 1.4E-5 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS09525 ec065b5e30a24e60ddeb0ac367165152 309 SUPERFAMILY SSF51161 104 290 3.05E-44 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS09525 ec065b5e30a24e60ddeb0ac367165152 309 PIRSF PIRSF000441 122 295 2.6E-52 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 hmeg3_RS21335 3705295a7eec83f0d5446d40fae255d0 553 TIGRFAM TIGR01686 FkbH: FkbH domain 182 507 2.2E-76 T 28-03-2018 IPR010037 FkbH domain hmeg3_RS21335 3705295a7eec83f0d5446d40fae255d0 553 Gene3D G3DSA:3.40.50.1000 181 347 1.3E-9 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS21335 3705295a7eec83f0d5446d40fae255d0 553 SUPERFAMILY SSF56784 183 301 5.3E-7 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS21335 3705295a7eec83f0d5446d40fae255d0 553 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 184 305 8.8E-16 T 28-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC hmeg3_RS18265 f683875b8ddf7aaf1f954897fcc6966b 71 Gene3D G3DSA:1.10.1470.10 1 69 2.1E-5 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS18265 f683875b8ddf7aaf1f954897fcc6966b 71 SUPERFAMILY SSF69047 1 61 1.28E-6 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 Pfam PF00202 Aminotransferase class-III 29 443 6.5E-90 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 PIRSF PIRSF000521 29 447 9.2E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 Gene3D G3DSA:3.90.1150.10 327 451 7.9E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 Gene3D G3DSA:3.90.1150.10 1 69 1.4E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 Gene3D G3DSA:3.40.640.10 70 326 1.2E-67 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS03725 f234f50b709ba40fdcac377371c81008 458 SUPERFAMILY SSF53383 10 446 1.09E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS10325 5996a008e44063f5a78b067c79e50630 202 Pfam PF02223 Thymidylate kinase 9 195 3.0E-51 T 28-03-2018 hmeg3_RS10325 5996a008e44063f5a78b067c79e50630 202 Hamap MF_00165 Thymidylate kinase [tmk]. 5 199 27.542 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 hmeg3_RS10325 5996a008e44063f5a78b067c79e50630 202 SUPERFAMILY SSF52540 1 201 1.6E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10325 5996a008e44063f5a78b067c79e50630 202 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 195 1.2E-54 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 hmeg3_RS10325 5996a008e44063f5a78b067c79e50630 202 Gene3D G3DSA:3.40.50.300 1 200 5.3E-52 T 28-03-2018 hmeg3_RS09960 9354654df447d667f7e7d8ce7f9f2ba9 271 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 229 255 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 hmeg3_RS09960 9354654df447d667f7e7d8ce7f9f2ba9 271 Pfam PF01148 Cytidylyltransferase family 3 266 1.8E-54 T 28-03-2018 hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 Gene3D G3DSA:1.10.1740.10 6 78 4.2E-15 T 28-03-2018 hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 Gene3D G3DSA:1.10.10.10 79 176 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 SUPERFAMILY SSF88946 9 91 7.06E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 Pfam PF04542 Sigma-70 region 2 13 75 2.8E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 174 1.1E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 Pfam PF08281 Sigma-70, region 4 119 171 3.1E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19605 eec028de8deb4eec6e4b14cefad79e1d 182 SUPERFAMILY SSF88659 114 175 1.1E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 Pfam PF13426 PAS domain 19 118 7.9E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS00865 b600bc3916000016cab784740926a512 186 SUPERFAMILY SSF55785 9 118 6.63E-12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS00865 b600bc3916000016cab784740926a512 186 Gene3D G3DSA:3.30.450.20 3 118 6.7E-12 T 28-03-2018 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 SUPERFAMILY SSF46894 114 182 1.05E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 ProSitePatterns PS00622 LuxR-type HTH domain signature. 141 168 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 SMART SM00421 124 181 9.0E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 120 1.8E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS00865 b600bc3916000016cab784740926a512 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 127 141 3.9E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 157 3.9E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 169 3.9E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 Pfam PF00196 Bacterial regulatory proteins, luxR family 127 179 2.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS00865 b600bc3916000016cab784740926a512 186 Gene3D G3DSA:1.10.10.10 119 183 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15595 e3a4ed21dbfd87c5746695f6316ab383 527 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 18 527 5.0E-282 T 28-03-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 hmeg3_RS15595 e3a4ed21dbfd87c5746695f6316ab383 527 SMART SM00858 25 95 1.9E-13 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS15595 e3a4ed21dbfd87c5746695f6316ab383 527 Pfam PF08666 SAF domain 25 93 8.1E-12 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS15595 e3a4ed21dbfd87c5746695f6316ab383 527 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 124 524 6.3E-144 T 28-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 hmeg3_RS05255 837ccf507b81eaa565c3fca15d877c07 260 Hamap MF_01830 UPF0317 protein . 11 260 51.201 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 hmeg3_RS05255 837ccf507b81eaa565c3fca15d877c07 260 PIRSF PIRSF029755 2 260 2.5E-118 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 hmeg3_RS05255 837ccf507b81eaa565c3fca15d877c07 260 Pfam PF07286 Protein of unknown function (DUF1445) 114 256 9.6E-66 T 28-03-2018 IPR009906 D-glutamate cyclase hmeg3_RS05255 837ccf507b81eaa565c3fca15d877c07 260 Gene3D G3DSA:3.40.1640.10 3 166 1.2E-66 T 28-03-2018 hmeg3_RS05255 837ccf507b81eaa565c3fca15d877c07 260 Gene3D G3DSA:3.40.1640.10 202 260 2.0E-7 T 28-03-2018 hmeg3_RS05255 837ccf507b81eaa565c3fca15d877c07 260 SUPERFAMILY SSF160920 10 256 1.57E-111 T 28-03-2018 hmeg3_RS20880 61da58bfa5969adf9386fa1720a8dd45 284 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 268 5.5E-72 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 hmeg3_RS20880 61da58bfa5969adf9386fa1720a8dd45 284 Pfam PF02673 Bacitracin resistance protein BacA 9 270 7.0E-86 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 hmeg3_RS20880 61da58bfa5969adf9386fa1720a8dd45 284 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 275 17.861 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 196 429 2.7E-74 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 107 121 1.4E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 357 368 1.4E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 187 209 1.4E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 229 249 1.4E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 50 178 1.8E-55 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 115 128 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 PIRSF PIRSF000185 22 432 6.1E-162 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 SMART SM00839 198 429 1.4E-94 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 Gene3D G3DSA:3.40.50.720 196 432 8.3E-77 T 28-03-2018 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 SUPERFAMILY SSF51735 196 431 7.04E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 Gene3D G3DSA:3.40.50.10860 52 195 1.3E-54 T 28-03-2018 hmeg3_RS04665 0e8c16c05353567f41caabb5c8fe60bf 432 SUPERFAMILY SSF53223 9 198 1.66E-68 T 28-03-2018 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Gene3D G3DSA:3.30.1490.100 266 372 4.1E-28 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 SUPERFAMILY SSF100879 263 367 1.43E-26 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 SUPERFAMILY SSF56672 5 256 5.07E-74 T 28-03-2018 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Gene3D G3DSA:1.10.150.20 191 265 1.3E-20 T 28-03-2018 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Gene3D G3DSA:3.30.70.270 141 190 4.3E-16 T 28-03-2018 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Gene3D G3DSA:3.30.70.270 65 140 1.8E-16 T 28-03-2018 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Pfam PF11799 impB/mucB/samB family C-terminal domain 255 367 6.8E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Pfam PF11798 IMS family HHH motif 188 218 7.8E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Pfam PF00817 impB/mucB/samB family 11 175 2.2E-41 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 hmeg3_RS02645 c96c4e759eeab646a2d26cdc98d0b6a2 391 Hamap MF_01113 DNA polymerase IV [dinB]. 5 381 32.032 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 9.9E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 Gene3D G3DSA:3.40.50.2300 1 138 1.3E-26 T 28-03-2018 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 SUPERFAMILY SSF52172 1 133 1.71E-26 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 SMART SM00421 153 210 1.0E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 Gene3D G3DSA:1.10.10.10 146 218 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 SUPERFAMILY SSF46894 148 216 4.42E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 Pfam PF00072 Response regulator receiver domain 4 121 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23670 cde6809a9b6c5f36c5f87fef8d23fe2f 218 SMART SM00448 2 121 3.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15550 da9445c3ddc51da93f8a2ded94c76008 167 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 1.4E-43 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type hmeg3_RS15550 da9445c3ddc51da93f8a2ded94c76008 167 Pfam PF02082 Transcriptional regulator 1 83 7.7E-27 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type hmeg3_RS15550 da9445c3ddc51da93f8a2ded94c76008 167 Gene3D G3DSA:1.10.10.10 1 146 8.2E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15550 da9445c3ddc51da93f8a2ded94c76008 167 SUPERFAMILY SSF46785 2 138 2.4E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15550 da9445c3ddc51da93f8a2ded94c76008 167 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 139 3.9E-64 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 hmeg3_RS20315 929a3d3198fcac4ba38aea1d7794b0aa 191 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 158 23.415 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 hmeg3_RS20315 929a3d3198fcac4ba38aea1d7794b0aa 191 Pfam PF03975 CheD chemotactic sensory transduction 47 154 1.4E-22 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 hmeg3_RS20315 929a3d3198fcac4ba38aea1d7794b0aa 191 SUPERFAMILY SSF64438 4 157 4.49E-39 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic hmeg3_RS04150 08b7d4856fae093534b62762ec8d7bb0 477 Gene3D G3DSA:1.20.1600.10 24 477 7.5E-98 T 28-03-2018 hmeg3_RS04150 08b7d4856fae093534b62762ec8d7bb0 477 SUPERFAMILY SSF56954 5 473 6.15E-107 T 28-03-2018 hmeg3_RS04150 08b7d4856fae093534b62762ec8d7bb0 477 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 471 1.1E-116 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS04150 08b7d4856fae093534b62762ec8d7bb0 477 Pfam PF02321 Outer membrane efflux protein 71 260 5.0E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS04150 08b7d4856fae093534b62762ec8d7bb0 477 Pfam PF02321 Outer membrane efflux protein 291 469 1.1E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 SUPERFAMILY SSF52343 407 549 7.73E-35 T 28-03-2018 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 Pfam PF00258 Flavodoxin 92 215 1.0E-25 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 SUPERFAMILY SSF52218 88 226 3.99E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS14120 edfba4828b9157551a79831592171606 549 Gene3D G3DSA:3.40.50.80 404 548 4.7E-23 T 28-03-2018 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 Pfam PF00175 Oxidoreductase NAD-binding domain 418 523 9.6E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00369 Flavodoxin signature 194 213 4.3E-9 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00369 Flavodoxin signature 170 180 4.3E-9 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00369 Flavodoxin signature 91 104 4.3E-9 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00369 Flavodoxin signature 139 150 4.3E-9 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 Gene3D G3DSA:2.40.30.10 243 400 6.4E-20 T 28-03-2018 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 Gene3D G3DSA:3.40.50.360 65 230 6.4E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 485 501 4.9E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 353 360 4.9E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 508 516 4.9E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 441 450 4.9E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 417 436 4.9E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 454 465 4.9E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS14120 edfba4828b9157551a79831592171606 549 SUPERFAMILY SSF63380 237 408 5.45E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 1.8E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 313 8.6E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 SMART SM00382 32 231 1.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 Pfam PF00005 ABC transporter 23 181 1.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 SUPERFAMILY SSF52540 33 302 9.84E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 Gene3D G3DSA:3.40.50.300 1 313 5.2E-69 T 28-03-2018 hmeg3_RS09575 f14021044f8bf21b605bed473570936e 320 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 Gene3D G3DSA:1.10.10.60 5 83 8.0E-17 T 28-03-2018 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 Gene3D G3DSA:1.10.357.10 84 223 1.1E-9 T 28-03-2018 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 85 2.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 SUPERFAMILY SSF48498 115 217 1.33E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 4.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 4.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 SUPERFAMILY SSF46689 28 93 5.64E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS03910 a8834fe8ae6b59b2fb003818431ef214 251 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 129 221 1.5E-6 T 28-03-2018 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 Gene3D G3DSA:1.10.760.10 25 106 2.4E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 SUPERFAMILY SSF46626 28 105 1.68E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 PRINTS PR00606 Class ID cytochrome C signature 29 42 4.1E-24 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 PRINTS PR00606 Class ID cytochrome C signature 94 104 4.1E-24 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 PRINTS PR00606 Class ID cytochrome C signature 67 80 4.1E-24 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 PRINTS PR00606 Class ID cytochrome C signature 82 92 4.1E-24 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 PRINTS PR00606 Class ID cytochrome C signature 44 57 4.1E-24 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS17815 04abb51767cd262f82809e011881b6f1 106 Pfam PF00034 Cytochrome c 29 106 2.2E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 Gene3D G3DSA:1.10.8.10 1 56 1.9E-18 T 28-03-2018 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 287 4.7E-92 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 SUPERFAMILY SSF46934 3 56 1.03E-12 T 28-03-2018 IPR009060 UBA-like GO:0005515 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 287 77.579 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 SUPERFAMILY SSF54713 56 145 9.16E-26 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 SUPERFAMILY SSF54713 149 287 1.88E-49 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 Gene3D G3DSA:3.30.479.20 155 286 1.6E-46 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 Pfam PF00889 Elongation factor TS 71 270 2.7E-70 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS09940 6236d978bc0b7a4560107609627ec7f0 294 Gene3D G3DSA:3.30.479.20 58 154 5.8E-25 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82714 185 270 3.4E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Gene3D G3DSA:3.30.2090.10 183 271 1.4E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Gene3D G3DSA:3.30.2090.10 721 809 5.9E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1043 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82693 46 126 2.88E-19 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 7.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 7.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 7.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 7.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 7.5E-21 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Gene3D G3DSA:3.30.70.1430 45 137 2.9E-18 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82866 806 1042 3.01E-44 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Pfam PF00873 AcrB/AcrD/AcrF family 6 1036 9.5E-237 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82714 723 807 2.75E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Gene3D G3DSA:1.20.1640.10 288 517 3.2E-43 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82866 294 505 1.44E-37 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Gene3D G3DSA:3.30.70.1430 567 665 4.0E-9 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82693 271 328 1.05E-21 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 SUPERFAMILY SSF82693 137 184 1.05E-21 T 28-03-2018 hmeg3_RS02145 0797d67ada9cfc383e3c1cc3ed0c9967 1046 Gene3D G3DSA:1.20.1640.10 827 1040 3.2E-26 T 28-03-2018 hmeg3_RS15795 79380d603dba7393b2c123390e4f3484 84 Pfam PF01313 Bacterial export proteins, family 3 4 74 1.7E-23 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS15795 79380d603dba7393b2c123390e4f3484 84 TIGRFAM TIGR01403 fliQ_rel_III: type III secretion protein, HrpO family 3 80 3.0E-30 T 28-03-2018 IPR006306 Type III secretion protein HrpO GO:0006810|GO:0016021 hmeg3_RS15795 79380d603dba7393b2c123390e4f3484 84 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 16 37 3.0E-25 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS15795 79380d603dba7393b2c123390e4f3484 84 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 52 74 3.0E-25 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS15795 79380d603dba7393b2c123390e4f3484 84 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 37 52 3.0E-25 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS15795 79380d603dba7393b2c123390e4f3484 84 PIRSF PIRSF004669 2 83 1.7E-21 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS16330 85091dea86cc7a61dd068f1e71234481 224 Pfam PF11010 Protein of unknown function (DUF2848) 22 215 5.6E-84 T 28-03-2018 IPR021269 Protein of unknown function DUF2848 hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 Gene3D G3DSA:1.10.10.10 3 84 3.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 Gene3D G3DSA:3.40.190.10 176 262 2.3E-25 T 28-03-2018 hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 SUPERFAMILY SSF46785 4 111 3.63E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 Pfam PF03466 LysR substrate binding domain 89 291 1.6E-41 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 SUPERFAMILY SSF53850 91 295 2.35E-45 T 28-03-2018 hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS08485 41ece8ab687a97344ce0aa82a55b0f66 300 Gene3D G3DSA:3.40.190.10 88 175 4.3E-14 T 28-03-2018 hmeg3_RS17510 9b6db599309f79869d2f57de49b6b965 575 SUPERFAMILY SSF52016 377 562 1.18E-59 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS17510 9b6db599309f79869d2f57de49b6b965 575 Pfam PF00920 Dehydratase family 42 557 8.8E-182 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17510 9b6db599309f79869d2f57de49b6b965 575 SUPERFAMILY SSF143975 9 374 1.26E-120 T 28-03-2018 hmeg3_RS17510 9b6db599309f79869d2f57de49b6b965 575 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS21695 b51fd584a6263f6853ecdf94027dc06c 367 SUPERFAMILY SSF53822 20 363 3.1E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS21695 b51fd584a6263f6853ecdf94027dc06c 367 Gene3D G3DSA:3.40.50.2300 17 201 5.4E-28 T 28-03-2018 hmeg3_RS21695 b51fd584a6263f6853ecdf94027dc06c 367 Gene3D G3DSA:3.40.50.2300 202 347 1.8E-20 T 28-03-2018 hmeg3_RS21695 b51fd584a6263f6853ecdf94027dc06c 367 Pfam PF13458 Periplasmic binding protein 27 355 8.7E-51 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 455 484 2.7E-42 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 378 405 2.7E-42 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 301 330 2.7E-42 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 407 436 2.7E-42 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 Pfam PF13426 PAS domain 29 114 2.1E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 493 7.1E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 SMART SM00283 280 527 2.6E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 30 110 1.3E-9 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 SMART SM00091 16 82 5.9E-4 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 Pfam PF00672 HAMP domain 226 274 1.1E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 SUPERFAMILY SSF58104 249 527 1.96E-61 T 28-03-2018 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 SUPERFAMILY SSF55785 28 118 4.01E-20 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 Gene3D G3DSA:1.10.287.950 335 530 3.4E-41 T 28-03-2018 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 Gene3D G3DSA:1.10.287.950 125 334 2.6E-11 T 28-03-2018 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 SMART SM00304 225 279 3.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19235 2045efe21bab2540893ca22a36568018 530 Gene3D G3DSA:3.40.50.10600 11 124 5.4E-19 T 28-03-2018 hmeg3_RS16210 7a7f61262abf8caeaff9aafcfc96cc44 329 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 117 314 3.4E-10 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 hmeg3_RS16210 7a7f61262abf8caeaff9aafcfc96cc44 329 PIRSF PIRSF028561 14 329 4.4E-79 T 28-03-2018 IPR014548 Predicted acyltransferase hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Gene3D G3DSA:1.10.287.130 515 576 1.4E-20 T 28-03-2018 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Gene3D G3DSA:1.20.120.160 1024 1121 1.7E-7 T 28-03-2018 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SMART SM00448 895 1006 2.7E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SUPERFAMILY SSF47384 498 581 1.79E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SUPERFAMILY SSF47226 989 1112 1.07E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SMART SM00388 515 580 6.1E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Gene3D G3DSA:3.30.450.20 220 335 9.7E-5 T 28-03-2018 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SMART SM00387 627 744 4.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SUPERFAMILY SSF52172 895 1019 2.99E-35 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Gene3D G3DSA:3.40.50.2300 889 1023 7.1E-37 T 28-03-2018 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 PRINTS PR00344 Bacterial sensor protein C-terminal signature 728 741 4.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 PRINTS PR00344 Bacterial sensor protein C-terminal signature 687 697 4.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 PRINTS PR00344 Bacterial sensor protein C-terminal signature 669 683 4.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 PRINTS PR00344 Bacterial sensor protein C-terminal signature 704 722 4.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Pfam PF00512 His Kinase A (phospho-acceptor) domain 515 579 1.5E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Gene3D G3DSA:3.30.565.10 584 749 5.3E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Gene3D G3DSA:3.30.450.20 370 514 2.9E-8 T 28-03-2018 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 627 743 3.9E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 Pfam PF00072 Response regulator receiver domain 897 1003 1.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15750 e22c745f091b47003f5ca409fc9ba558 1122 SUPERFAMILY SSF55874 569 744 8.25E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS21905 fa1e6d53f3b3c86cee7fc728d503b35b 427 Gene3D G3DSA:3.30.450.90 11 145 1.9E-44 T 28-03-2018 hmeg3_RS21905 fa1e6d53f3b3c86cee7fc728d503b35b 427 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 240 254 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 hmeg3_RS21905 fa1e6d53f3b3c86cee7fc728d503b35b 427 SUPERFAMILY SSF52540 35 423 1.91E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21905 fa1e6d53f3b3c86cee7fc728d503b35b 427 Gene3D G3DSA:3.40.50.300 146 426 2.3E-60 T 28-03-2018 hmeg3_RS21905 fa1e6d53f3b3c86cee7fc728d503b35b 427 Pfam PF00437 Type II/IV secretion system protein 46 312 7.0E-86 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 SUPERFAMILY SSF51735 5 192 4.35E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 189 1.6E-45 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Gene3D G3DSA:1.10.1040.10 348 436 1.9E-10 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Gene3D G3DSA:3.40.50.720 2 191 2.9E-40 T 28-03-2018 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Gene3D G3DSA:1.10.1040.10 192 299 2.1E-18 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 293 3.9E-14 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Pfam PF00378 Enoyl-CoA hydratase/isomerase 500 649 2.0E-14 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 SUPERFAMILY SSF48179 192 310 5.36E-21 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 Gene3D G3DSA:3.90.226.10 474 793 8.2E-38 T 28-03-2018 hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 SUPERFAMILY SSF52096 478 791 6.22E-37 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS22350 1a3163e60794ecc7bbe05b08315404ac 795 SUPERFAMILY SSF48179 343 457 1.36E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 Gene3D G3DSA:3.30.70.920 56 154 5.9E-19 T 28-03-2018 hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 SUPERFAMILY SSF46785 6 65 6.43E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 SUPERFAMILY SSF54909 68 147 3.35E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.2E-17 T 28-03-2018 hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 Pfam PF01037 Lrp/AsnC ligand binding domain 72 145 3.7E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 Gene3D G3DSA:1.10.10.10 1 55 7.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.0E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.0E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.0E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS01895 41d71402efe7d7a27f7c66771683efa3 155 SMART SM00344 6 115 3.4E-29 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 6.8E-106 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 Gene3D G3DSA:3.40.30.10 4 152 1.4E-34 T 28-03-2018 hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 Pfam PF00578 AhpC/TSA family 8 132 1.6E-33 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 SUPERFAMILY SSF52833 1 187 2.7E-58 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 PIRSF PIRSF000239 1 187 6.2E-57 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 5.8E-6 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 hmeg3_RS02770 514049709aabc13f26475cfdccfcf72c 187 Gene3D G3DSA:3.30.1020.10 153 183 1.3E-10 T 28-03-2018 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 SUPERFAMILY SSF53613 226 497 6.7E-64 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 233 495 9.0E-58 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 Gene3D G3DSA:3.40.50.10260 2 228 6.7E-53 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 Pfam PF01256 Carbohydrate kinase 250 472 1.7E-49 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 14 213 2.2E-30 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 SUPERFAMILY SSF64153 4 248 4.32E-51 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 227 499 20.718 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 PIRSF PIRSF017184 3 502 2.2E-104 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 Gene3D G3DSA:3.40.1190.20 229 501 2.6E-47 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 Pfam PF03853 YjeF-related protein N-terminus 25 193 3.3E-38 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 hmeg3_RS10605 38c7fa49ad0fadc6db3c8d20af65c360 503 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 214 20.645 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 hmeg3_RS00045 931884111e19d9724d2a346a1f7d14ef 341 Gene3D G3DSA:2.60.40.1090 29 185 0.062 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS00045 931884111e19d9724d2a346a1f7d14ef 341 Gene3D G3DSA:2.60.40.1090 209 341 2.8E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS00045 931884111e19d9724d2a346a1f7d14ef 341 Pfam PF00419 Fimbrial protein 198 341 9.9E-8 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS00045 931884111e19d9724d2a346a1f7d14ef 341 SUPERFAMILY SSF49401 207 341 4.82E-14 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.2E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 145 198 6.1E-10 T 28-03-2018 hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 Gene3D G3DSA:1.10.357.10 61 201 1.4E-15 T 28-03-2018 hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 SUPERFAMILY SSF46689 2 76 1.89E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS00670 e8415ecaa77e694882b9c3edc927877a 211 Gene3D G3DSA:1.10.10.60 1 60 6.1E-20 T 28-03-2018 hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 Gene3D G3DSA:3.20.20.450 410 679 7.7E-100 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SUPERFAMILY SSF55785 136 241 3.7E-23 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SMART SM00091 124 191 3.7E-7 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 Pfam PF00990 Diguanylate cyclase, GGDEF domain 247 404 9.3E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 Gene3D G3DSA:3.30.450.20 98 240 6.6E-29 T 28-03-2018 hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SMART SM00052 421 666 6.0E-118 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 Pfam PF00563 EAL domain 430 661 3.7E-71 T 28-03-2018 IPR001633 EAL domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SMART SM00086 194 236 1.9E-8 T 28-03-2018 IPR001610 PAC motif hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 244 404 1.3E-38 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 124 241 3.5E-25 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 Gene3D G3DSA:3.30.70.270 241 405 2.2E-56 T 28-03-2018 hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SUPERFAMILY SSF55073 252 404 4.16E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SMART SM00267 236 408 1.8E-57 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 Pfam PF13426 PAS domain 136 235 1.3E-15 T 28-03-2018 IPR000014 PAS domain hmeg3_RS13240 54361b7c35c1586f1def895e87e4af71 681 SUPERFAMILY SSF141868 427 673 5.1E-89 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18485 a54e6ffa52e6300af5477bf420521d36 432 Pfam PF07690 Major Facilitator Superfamily 27 360 1.2E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18485 a54e6ffa52e6300af5477bf420521d36 432 Gene3D G3DSA:1.20.1250.20 2 226 1.7E-26 T 28-03-2018 hmeg3_RS18485 a54e6ffa52e6300af5477bf420521d36 432 Gene3D G3DSA:1.20.1250.20 232 429 1.5E-22 T 28-03-2018 hmeg3_RS18485 a54e6ffa52e6300af5477bf420521d36 432 SUPERFAMILY SSF103473 14 427 1.57E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS22665 ff875f2994b2199cac89a277b9b7a47d 270 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS22665 ff875f2994b2199cac89a277b9b7a47d 270 Gene3D G3DSA:3.40.50.300 8 230 7.0E-61 T 28-03-2018 hmeg3_RS22665 ff875f2994b2199cac89a277b9b7a47d 270 Pfam PF00005 ABC transporter 31 170 4.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS22665 ff875f2994b2199cac89a277b9b7a47d 270 SMART SM00382 40 221 4.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22665 ff875f2994b2199cac89a277b9b7a47d 270 SUPERFAMILY SSF52540 11 239 1.52E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21275 441e6c6a350260397540a59abb6b723e 344 Gene3D G3DSA:2.60.120.620 79 313 1.3E-22 T 28-03-2018 hmeg3_RS21275 441e6c6a350260397540a59abb6b723e 344 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 90 296 2.6E-7 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase hmeg3_RS21275 441e6c6a350260397540a59abb6b723e 344 SUPERFAMILY SSF51197 84 316 2.66E-20 T 28-03-2018 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Gene3D G3DSA:1.10.10.10 273 340 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 103 331 2.6E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Pfam PF04539 Sigma-70 region 3 187 263 3.1E-12 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 302 328 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 SUPERFAMILY SSF88946 68 177 1.02E-44 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 PRINTS PR00046 Major sigma-70 factor signature 281 293 5.1E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 PRINTS PR00046 Major sigma-70 factor signature 317 328 5.1E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 PRINTS PR00046 Major sigma-70 factor signature 155 163 5.1E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 PRINTS PR00046 Major sigma-70 factor signature 302 317 5.1E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 PRINTS PR00046 Major sigma-70 factor signature 131 144 5.1E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 60 343 1.4E-130 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 SUPERFAMILY SSF88659 180 254 2.18E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Gene3D G3DSA:1.10.601.10 4 176 1.2E-59 T 28-03-2018 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Gene3D G3DSA:1.10.10.10 177 230 3.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 4 343 37.943 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Pfam PF04542 Sigma-70 region 2 107 176 1.2E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Pfam PF04545 Sigma-70, region 4 277 329 7.7E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 SUPERFAMILY SSF88659 240 335 5.79E-24 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 131 144 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08835 ade38dc04983651cbdd4ea000b6e11de 343 Pfam PF00140 Sigma-70 factor, region 1.2 69 102 6.4E-9 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 148 163 9.7E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 47 62 9.7E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 73 85 9.7E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 68 85 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 SUPERFAMILY SSF50891 30 193 2.78E-57 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 Gene3D G3DSA:2.40.100.10 19 194 9.4E-51 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 PIRSF PIRSF001467 19 193 6.5E-26 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 hmeg3_RS08990 a9c20cc174926de9fbe124804abf769e 194 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 34 192 3.8E-46 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS19940 5a8e06ada614dcc5ab75515b7a71bf8e 478 PIRSF PIRSF000204 1 478 6.6E-209 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 hmeg3_RS19940 5a8e06ada614dcc5ab75515b7a71bf8e 478 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 475 1.5E-189 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 hmeg3_RS19940 5a8e06ada614dcc5ab75515b7a71bf8e 478 SUPERFAMILY SSF52467 307 478 1.0E-71 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS19940 5a8e06ada614dcc5ab75515b7a71bf8e 478 Gene3D G3DSA:3.40.50.1220 305 478 2.5E-81 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS04430 bf05fbd0e0dc24f55ca76b44f12c9042 266 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 60 78 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 hmeg3_RS04430 bf05fbd0e0dc24f55ca76b44f12c9042 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 4.2E-91 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 hmeg3_RS04430 bf05fbd0e0dc24f55ca76b44f12c9042 266 Gene3D G3DSA:3.20.20.70 11 266 2.5E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS04430 bf05fbd0e0dc24f55ca76b44f12c9042 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 266 34.456 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 hmeg3_RS04430 bf05fbd0e0dc24f55ca76b44f12c9042 266 SUPERFAMILY SSF51366 1 265 6.12E-84 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS17545 79a15ae501128e1d4a229e9c3813da45 256 Pfam PF01738 Dienelactone hydrolase family 40 253 6.5E-34 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS17545 79a15ae501128e1d4a229e9c3813da45 256 SUPERFAMILY SSF53474 39 254 1.26E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS17545 79a15ae501128e1d4a229e9c3813da45 256 Gene3D G3DSA:3.40.50.1820 79 256 3.2E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 3.7E-57 T 28-03-2018 hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 SUPERFAMILY SSF51735 10 252 1.81E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 Gene3D G3DSA:3.40.50.720 47 253 1.2E-59 T 28-03-2018 hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 Gene3D G3DSA:3.40.50.720 2 46 4.9E-6 T 28-03-2018 hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23210 a0dbf81e50ae3e155f0281d67248cfec 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23640 6ec581a2efa8dd13778fad03d62f51dd 187 Pfam PF07484 Phage Tail Collar Domain 5 60 6.0E-21 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS23640 6ec581a2efa8dd13778fad03d62f51dd 187 Gene3D G3DSA:3.90.1340.10 1 65 7.6E-17 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS23640 6ec581a2efa8dd13778fad03d62f51dd 187 SUPERFAMILY SSF88874 2 172 2.62E-35 T 28-03-2018 hmeg3_RS18735 5513f0cc2337f0b62e9758e1e31cab63 59 Pfam PF11755 Protein of unknown function (DUF3311) 4 51 4.9E-20 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 hmeg3_RS00465 fd3f76eae765541f4ea4c8af61dfc9e5 292 SUPERFAMILY SSF103481 33 138 6.28E-12 T 28-03-2018 hmeg3_RS00465 fd3f76eae765541f4ea4c8af61dfc9e5 292 Pfam PF00892 EamA-like transporter family 2 135 1.3E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS00465 fd3f76eae765541f4ea4c8af61dfc9e5 292 TIGRFAM TIGR00688 rarD: protein RarD 5 252 4.1E-64 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 hmeg3_RS00465 fd3f76eae765541f4ea4c8af61dfc9e5 292 SUPERFAMILY SSF103481 200 278 5.75E-7 T 28-03-2018 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 7.0E-251 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 SUPERFAMILY SSF53697 243 605 3.62E-111 T 28-03-2018 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 39.472 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Gene3D G3DSA:3.40.50.10490 455 603 4.3E-48 T 28-03-2018 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Gene3D G3DSA:3.40.50.10490 238 454 5.8E-59 T 28-03-2018 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Gene3D G3DSA:3.60.20.10 2 237 6.0E-66 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Pfam PF13522 Glutamine amidotransferase domain 61 190 1.0E-22 T 28-03-2018 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 SUPERFAMILY SSF56235 2 232 6.26E-72 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Pfam PF01380 SIS domain 289 412 3.1E-27 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS01890 d7a0bfca857fe26dd488929c8d5be1bb 605 Pfam PF01380 SIS domain 459 587 1.7E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS13145 5f7eaf1396b33307c8cfbc2883af6393 280 Hamap MF_00697 UPF0276 protein . 7 280 44.54 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 hmeg3_RS13145 5f7eaf1396b33307c8cfbc2883af6393 280 SUPERFAMILY SSF51658 40 227 1.89E-6 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain hmeg3_RS13145 5f7eaf1396b33307c8cfbc2883af6393 280 Gene3D G3DSA:3.20.20.150 2 277 1.3E-81 T 28-03-2018 hmeg3_RS13145 5f7eaf1396b33307c8cfbc2883af6393 280 Pfam PF05114 Protein of unknown function (DUF692) 6 273 3.4E-103 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 hmeg3_RS06880 d3c78fa161014c6d3fcb52cb79dbc330 721 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 173 3.3E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS06880 d3c78fa161014c6d3fcb52cb79dbc330 721 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 80 721 3.3E-93 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS06880 d3c78fa161014c6d3fcb52cb79dbc330 721 Gene3D G3DSA:2.40.170.20 186 721 1.4E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS06880 d3c78fa161014c6d3fcb52cb79dbc330 721 SUPERFAMILY SSF56935 40 721 1.62E-119 T 28-03-2018 hmeg3_RS06880 d3c78fa161014c6d3fcb52cb79dbc330 721 Pfam PF00593 TonB dependent receptor 252 720 4.3E-53 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS06880 d3c78fa161014c6d3fcb52cb79dbc330 721 Gene3D G3DSA:2.170.130.10 43 180 7.6E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS19495 3756577589fac596285c2af6b16ecedb 149 Gene3D G3DSA:1.10.10.410 91 147 1.6E-19 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal hmeg3_RS19495 3756577589fac596285c2af6b16ecedb 149 SUPERFAMILY SSF89095 1 146 2.3E-44 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 hmeg3_RS19495 3756577589fac596285c2af6b16ecedb 149 Gene3D G3DSA:1.10.1510.10 1 90 3.2E-30 T 28-03-2018 hmeg3_RS19495 3756577589fac596285c2af6b16ecedb 149 Pfam PF09424 Yqey-like protein 4 146 8.9E-56 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 SUPERFAMILY SSF52374 3 172 1.39E-83 T 28-03-2018 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 SUPERFAMILY SSF52374 243 397 1.39E-83 T 28-03-2018 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 2.7E-21 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 145 166 2.7E-21 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 2.7E-21 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 Pfam PF00579 tRNA synthetases class I (W and Y) 243 309 1.2E-9 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 Pfam PF00579 tRNA synthetases class I (W and Y) 5 175 9.8E-47 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 Gene3D G3DSA:3.40.50.620 2 264 7.3E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 173 2.8E-56 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS17140 295d36dbcc0be99a03082e3f8c3814a3 399 Gene3D G3DSA:1.10.240.10 265 393 2.7E-25 T 28-03-2018 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 SUPERFAMILY SSF52540 225 478 1.48E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 SUPERFAMILY SSF52540 541 580 2.66E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 SUPERFAMILY SSF52540 404 486 2.66E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 SUPERFAMILY SSF52540 616 689 2.66E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 Gene3D G3DSA:3.40.50.300 44 478 1.1E-24 T 28-03-2018 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 4 707 1.8E-183 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 SMART SM00487 264 491 1.2E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 Gene3D G3DSA:3.40.50.300 698 1025 0.041 T 28-03-2018 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 Pfam PF04851 Type III restriction enzyme, res subunit 265 453 1.3E-14 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 2 207 4.2E-43 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 Gene3D G3DSA:3.40.50.300 532 697 2.0E-5 T 28-03-2018 hmeg3_RS12995 2db0045e764b64423985c214ffb4ee4a 1040 Pfam PF11867 Domain of unknown function (DUF3387) 706 1035 1.9E-122 T 28-03-2018 IPR021810 Protein of unknown function DUF3387 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 SUPERFAMILY SSF47384 219 301 9.22E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 SUPERFAMILY SSF55874 291 461 8.25E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 Gene3D G3DSA:3.30.565.10 307 465 1.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 Pfam PF08521 Two-component sensor kinase N-terminal 17 159 1.1E-34 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 Gene3D G3DSA:1.10.287.130 223 297 2.8E-10 T 28-03-2018 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 Gene3D G3DSA:1.20.5.1040 3 58 6.5E-7 T 28-03-2018 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 SMART SM00388 236 301 1.8E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 SMART SM00387 348 463 2.1E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 300 6.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 418 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07070 8e059c292c8604fb011845ae27c61e49 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 461 1.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Gene3D G3DSA:1.10.10.60 155 202 2.7E-4 T 28-03-2018 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Pfam PF02805 Metal binding domain of Ada 27 90 4.1E-33 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Pfam PF12833 Helix-turn-helix domain 122 198 3.8E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 SUPERFAMILY SSF46767 285 366 2.75E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 101 145 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 286 365 2.4E-35 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 336 342 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Gene3D G3DSA:1.10.10.10 284 369 1.1E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 SMART SM00342 115 198 8.3E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 SUPERFAMILY SSF53155 205 284 1.67E-21 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Gene3D G3DSA:1.10.10.60 96 154 9.0E-15 T 28-03-2018 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 287 366 3.3E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 SUPERFAMILY SSF46689 103 148 2.1E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Gene3D G3DSA:3.40.10.10 18 93 2.2E-27 T 28-03-2018 IPR035451 Ada-like domain hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 SUPERFAMILY SSF57884 25 108 1.12E-32 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 PIRSF PIRSF000409 13 369 2.5E-144 T 28-03-2018 IPR016221 Bifunctional regulatory protein Ada hmeg3_RS14220 94383a53c71d3513917af1bc207732c2 370 Gene3D G3DSA:3.30.160.70 203 283 6.9E-21 T 28-03-2018 hmeg3_RS07390 40368a1403671795552c2309209206df 292 Pfam PF03466 LysR substrate binding domain 88 284 3.0E-36 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS07390 40368a1403671795552c2309209206df 292 Gene3D G3DSA:3.40.190.10 91 174 4.9E-16 T 28-03-2018 hmeg3_RS07390 40368a1403671795552c2309209206df 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07390 40368a1403671795552c2309209206df 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07390 40368a1403671795552c2309209206df 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07390 40368a1403671795552c2309209206df 292 SUPERFAMILY SSF53850 88 287 6.33E-35 T 28-03-2018 hmeg3_RS07390 40368a1403671795552c2309209206df 292 SUPERFAMILY SSF46785 2 84 9.74E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07390 40368a1403671795552c2309209206df 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07390 40368a1403671795552c2309209206df 292 Gene3D G3DSA:3.40.190.10 175 254 1.4E-15 T 28-03-2018 hmeg3_RS07390 40368a1403671795552c2309209206df 292 Gene3D G3DSA:1.10.10.10 1 88 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 Pfam PF01494 FAD binding domain 2 340 1.5E-81 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 SUPERFAMILY SSF51905 1 171 6.76E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 SUPERFAMILY SSF51905 273 386 6.76E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 Gene3D G3DSA:3.50.50.60 3 167 1.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 SUPERFAMILY SSF54373 174 274 1.49E-42 T 28-03-2018 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 Gene3D G3DSA:3.30.9.10 168 282 3.9E-49 T 28-03-2018 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 Gene3D G3DSA:3.30.9.10 307 387 1.6E-16 T 28-03-2018 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.8E-28 T 28-03-2018 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 2.8E-28 T 28-03-2018 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.8E-28 T 28-03-2018 hmeg3_RS01255 a91e83acda5506aa41edc15db20920f6 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.8E-28 T 28-03-2018 hmeg3_RS13835 e8eaf61b4f21cabb188352fcdd2d2840 328 Pfam PF06166 Protein of unknown function (DUF979) 10 327 2.3E-121 T 28-03-2018 IPR009323 Protein of unknown function DUF979 hmeg3_RS17660 be9ea31ff48e28a729ccdd798252b6ed 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 275 2.1E-33 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS17660 be9ea31ff48e28a729ccdd798252b6ed 291 Gene3D G3DSA:1.10.3470.10 1 279 2.7E-42 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS02155 abba9b366dde5f51d1eaa85c91606daf 414 Pfam PF02321 Outer membrane efflux protein 29 213 7.1E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS02155 abba9b366dde5f51d1eaa85c91606daf 414 Pfam PF02321 Outer membrane efflux protein 238 409 8.8E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS02155 abba9b366dde5f51d1eaa85c91606daf 414 SUPERFAMILY SSF56954 3 413 3.92E-56 T 28-03-2018 hmeg3_RS02155 abba9b366dde5f51d1eaa85c91606daf 414 Gene3D G3DSA:1.20.1600.10 20 414 1.1E-45 T 28-03-2018 hmeg3_RS18825 3b84444a8fe6086ec6bc659eb4659f59 218 Pfam PF01467 Cytidylyltransferase-like 9 189 4.0E-22 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 hmeg3_RS18825 3b84444a8fe6086ec6bc659eb4659f59 218 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 5 217 27.367 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 hmeg3_RS18825 3b84444a8fe6086ec6bc659eb4659f59 218 SUPERFAMILY SSF52374 6 217 3.85E-47 T 28-03-2018 hmeg3_RS18825 3b84444a8fe6086ec6bc659eb4659f59 218 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 9 216 5.2E-47 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 hmeg3_RS18825 3b84444a8fe6086ec6bc659eb4659f59 218 Gene3D G3DSA:3.40.50.620 1 218 5.8E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 Gene3D G3DSA:1.10.10.10 1 93 5.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 SUPERFAMILY SSF46785 3 93 1.21E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 Pfam PF12840 Helix-turn-helix domain 10 69 5.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 SMART SM00418 8 89 2.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS02370 0e43233f67910728258be80cd4f12f68 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS12325 aa158b0eb3ca1713b384eede0de347ff 277 Gene3D G3DSA:3.40.50.300 1 270 3.3E-62 T 28-03-2018 hmeg3_RS12325 aa158b0eb3ca1713b384eede0de347ff 277 SUPERFAMILY SSF52540 1 238 4.65E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12325 aa158b0eb3ca1713b384eede0de347ff 277 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 241 3.2E-97 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 hmeg3_RS12325 aa158b0eb3ca1713b384eede0de347ff 277 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS12325 aa158b0eb3ca1713b384eede0de347ff 277 Pfam PF00005 ABC transporter 17 173 6.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS12325 aa158b0eb3ca1713b384eede0de347ff 277 SMART SM00382 26 230 1.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 SUPERFAMILY SSF51735 9 240 8.66E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 6.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 Gene3D G3DSA:3.40.50.720 2 241 3.3E-71 T 28-03-2018 hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 238 9.9E-57 T 28-03-2018 hmeg3_RS20545 66eef04daecba209b4e766655bc93a9f 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS00140 6a0cb5cfd82fe135569f0d9cbd741ff6 494 Gene3D G3DSA:3.40.605.10 2 269 1.8E-84 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00140 6a0cb5cfd82fe135569f0d9cbd741ff6 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00140 6a0cb5cfd82fe135569f0d9cbd741ff6 494 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00140 6a0cb5cfd82fe135569f0d9cbd741ff6 494 SUPERFAMILY SSF53720 8 485 3.53E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00140 6a0cb5cfd82fe135569f0d9cbd741ff6 494 Gene3D G3DSA:3.40.309.10 270 467 2.0E-72 T 28-03-2018 hmeg3_RS00140 6a0cb5cfd82fe135569f0d9cbd741ff6 494 Pfam PF00171 Aldehyde dehydrogenase family 22 480 2.0E-167 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 Pfam PF02754 Cysteine-rich domain 171 258 9.3E-11 T 28-03-2018 IPR004017 Cysteine-rich domain hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 Pfam PF02754 Cysteine-rich domain 312 396 6.8E-13 T 28-03-2018 IPR004017 Cysteine-rich domain hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 Gene3D G3DSA:3.30.70.20 6 33 0.0099 T 28-03-2018 hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 SUPERFAMILY SSF54862 22 122 2.09E-20 T 28-03-2018 hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 PIRSF PIRSF000139 7 417 7.1E-118 T 28-03-2018 hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 Gene3D G3DSA:3.30.70.20 34 76 4.4E-8 T 28-03-2018 hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 Gene3D G3DSA:3.30.70.20 77 363 1.7E-4 T 28-03-2018 hmeg3_RS04850 3dfdb3523165e98a79a59c1f7ef5b35d 417 Pfam PF12838 4Fe-4S dicluster domain 24 89 1.4E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 Gene3D G3DSA:3.30.70.20 11 89 1.5E-8 T 28-03-2018 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 7 161 6.6E-64 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 Pfam PF04060 Putative Fe-S cluster 17 49 4.9E-14 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 PIRSF PIRSF005784 180 215 1000.0 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 PIRSF PIRSF005784 3 163 9.4E-62 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 119 130 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 Pfam PF14697 4Fe-4S dicluster domain 82 136 4.2E-17 T 28-03-2018 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 Gene3D G3DSA:3.30.70.20 121 161 2.9E-6 T 28-03-2018 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 SUPERFAMILY SSF54862 12 141 1.29E-29 T 28-03-2018 hmeg3_RS14605 8864155dcb237333453d046cefa5642f 237 Gene3D G3DSA:3.30.70.20 90 120 2.6E-11 T 28-03-2018 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 Gene3D G3DSA:1.10.274.10 28 145 8.4E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 Pfam PF05524 PEP-utilising enzyme, N-terminal 7 130 3.3E-28 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 193 204 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 Gene3D G3DSA:3.20.20.60 264 584 5.2E-89 T 28-03-2018 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 459 474 2.5E-20 T 28-03-2018 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 302 321 2.5E-20 T 28-03-2018 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 476 491 2.5E-20 T 28-03-2018 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 524 2.5E-20 T 28-03-2018 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 SUPERFAMILY SSF47831 29 147 1.44E-31 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 SUPERFAMILY SSF52009 129 255 9.55E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 Gene3D G3DSA:3.50.30.10 146 263 1.7E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 6 569 1.7E-154 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 260 552 5.7E-103 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 459 477 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 Pfam PF00391 PEP-utilising enzyme, mobile domain 164 234 4.3E-21 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 PIRSF PIRSF000732 1 585 7.9E-199 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 hmeg3_RS22980 8d4307c6f3bd6357e4b3182e15dd1986 597 SUPERFAMILY SSF51621 259 558 6.81E-93 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 SMART SM00448 1 112 2.9E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 SUPERFAMILY SSF52172 1 121 1.99E-37 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 1.9E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 SMART SM00862 145 218 4.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 Pfam PF00072 Response regulator receiver domain 3 112 5.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 SUPERFAMILY SSF46894 119 219 2.83E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 Gene3D G3DSA:3.40.50.2300 1 115 4.0E-36 T 28-03-2018 hmeg3_RS20205 e5824118042e74afc143e18376200c27 238 Gene3D G3DSA:1.10.10.10 116 223 4.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07620 4b6baa4fcb5ea4cf2bdb0180bdb78165 340 Gene3D G3DSA:3.40.50.1100 143 321 4.4E-32 T 28-03-2018 hmeg3_RS07620 4b6baa4fcb5ea4cf2bdb0180bdb78165 340 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 309 4.2E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS07620 4b6baa4fcb5ea4cf2bdb0180bdb78165 340 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 45 59 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 hmeg3_RS07620 4b6baa4fcb5ea4cf2bdb0180bdb78165 340 SUPERFAMILY SSF53686 8 318 3.01E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS07620 4b6baa4fcb5ea4cf2bdb0180bdb78165 340 Gene3D G3DSA:3.40.50.1100 32 142 1.3E-25 T 28-03-2018 hmeg3_RS03320 d957d4caa37b588f07eae08b0b3c42b8 203 SUPERFAMILY SSF52833 59 199 3.26E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03320 d957d4caa37b588f07eae08b0b3c42b8 203 Gene3D G3DSA:3.40.30.10 124 200 5.8E-4 T 28-03-2018 hmeg3_RS03320 d957d4caa37b588f07eae08b0b3c42b8 203 Gene3D G3DSA:3.40.30.10 56 117 3.9E-6 T 28-03-2018 hmeg3_RS07315 07e8d96b52cb414c01abc963ac2bf7fe 279 Gene3D G3DSA:3.40.50.1820 2 279 3.7E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07315 07e8d96b52cb414c01abc963ac2bf7fe 279 Pfam PF12146 Serine aminopeptidase, S33 28 259 6.0E-68 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS07315 07e8d96b52cb414c01abc963ac2bf7fe 279 SUPERFAMILY SSF53474 12 262 7.43E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06495 0cfa5e6c51c45c601c40d49d1b190c2b 299 SUPERFAMILY SSF53474 8 297 1.8E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06495 0cfa5e6c51c45c601c40d49d1b190c2b 299 Gene3D G3DSA:3.40.50.1820 5 299 1.2E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06495 0cfa5e6c51c45c601c40d49d1b190c2b 299 PRINTS PR00412 Epoxide hydrolase signature 60 75 1.3E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06495 0cfa5e6c51c45c601c40d49d1b190c2b 299 PRINTS PR00412 Epoxide hydrolase signature 274 296 1.3E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06495 0cfa5e6c51c45c601c40d49d1b190c2b 299 PRINTS PR00412 Epoxide hydrolase signature 40 58 1.3E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06495 0cfa5e6c51c45c601c40d49d1b190c2b 299 Pfam PF00561 alpha/beta hydrolase fold 35 172 8.1E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS17150 6ed38d7f110c3d64e629368221db953e 208 Gene3D G3DSA:3.90.870.10 1 206 1.9E-61 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain hmeg3_RS17150 6ed38d7f110c3d64e629368221db953e 208 SUPERFAMILY SSF55821 1 204 1.13E-63 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain hmeg3_RS17150 6ed38d7f110c3d64e629368221db953e 208 Pfam PF01300 Telomere recombination 23 199 6.7E-46 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 hmeg3_RS17150 6ed38d7f110c3d64e629368221db953e 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 9.6E-62 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 hmeg3_RS21240 1eb5b72e6b2b48f04e5217011111766a 218 Gene3D G3DSA:2.160.10.10 84 212 3.5E-5 T 28-03-2018 hmeg3_RS21240 1eb5b72e6b2b48f04e5217011111766a 218 SUPERFAMILY SSF51161 16 192 4.85E-7 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 SMART SM00028 139 167 41.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 SMART SM00028 105 138 5.2E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 SMART SM00028 71 104 96.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 SUPERFAMILY SSF48452 47 177 1.31E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 SUPERFAMILY SSF54427 306 411 6.87E-18 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 Gene3D G3DSA:1.25.40.10 41 124 3.7E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 Pfam PF14559 Tetratricopeptide repeat 81 140 4.4E-9 T 28-03-2018 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 Gene3D G3DSA:3.10.450.50 297 416 7.2E-11 T 28-03-2018 hmeg3_RS09000 fa84eb6bc2f293e2b0f25313b861e684 417 Gene3D G3DSA:1.25.40.10 125 183 5.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 SMART SM00922 128 257 5.3E-14 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 SUPERFAMILY SSF51604 98 386 4.06E-75 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 1.2E-32 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 Gene3D G3DSA:3.20.20.120 101 375 5.8E-62 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 Gene3D G3DSA:3.30.390.10 6 100 7.3E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 SUPERFAMILY SSF54826 1 112 6.37E-33 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 hmeg3_RS05045 0c89a8404ffa22e40ba16509f970c1ad 402 Pfam PF13378 Enolase C-terminal domain-like 187 377 2.0E-41 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 SUPERFAMILY SSF51621 476 800 1.41E-89 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Gene3D G3DSA:3.30.470.20 204 368 1.1E-44 T 28-03-2018 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 10 800 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 493 799 2.2E-58 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Gene3D G3DSA:3.20.20.60 489 802 1.1E-97 T 28-03-2018 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 360 5.1E-118 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Pfam PF00391 PEP-utilising enzyme, mobile domain 395 466 5.1E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 SUPERFAMILY SSF56059 8 396 3.18E-109 T 28-03-2018 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 425 436 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Gene3D G3DSA:3.30.1490.20 6 203 9.8E-56 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 PIRSF PIRSF000854 4 802 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 Gene3D G3DSA:3.50.30.10 369 487 2.7E-37 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 SUPERFAMILY SSF52009 359 478 6.15E-34 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 hmeg3_RS10025 848ead1f2d9b62c36400011c2b5fe1d6 802 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 705 723 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 hmeg3_RS23240 cb5541049fff0eda37375f027f21c3c8 266 PIRSF PIRSF039085 6 254 8.0E-114 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS23240 cb5541049fff0eda37375f027f21c3c8 266 SMART SM00382 34 226 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23240 cb5541049fff0eda37375f027f21c3c8 266 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS23240 cb5541049fff0eda37375f027f21c3c8 266 Pfam PF00005 ABC transporter 25 178 3.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23240 cb5541049fff0eda37375f027f21c3c8 266 Gene3D G3DSA:3.40.50.300 5 266 2.7E-75 T 28-03-2018 hmeg3_RS23240 cb5541049fff0eda37375f027f21c3c8 266 SUPERFAMILY SSF52540 9 248 4.09E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS22265 57176170fc61a34b37e14766ff7dbfb9 269 Pfam PF06629 MltA-interacting protein MipA 53 269 1.9E-40 T 28-03-2018 IPR010583 MltA-interacting MipA hmeg3_RS09510 e0badc41850f005bfbf31ba70f710a71 610 SUPERFAMILY SSF53383 205 604 1.07E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS09510 e0badc41850f005bfbf31ba70f710a71 610 Pfam PF00266 Aminotransferase class-V 227 596 3.7E-148 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS09510 e0badc41850f005bfbf31ba70f710a71 610 Gene3D G3DSA:3.90.1150.10 485 603 7.5E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS09510 e0badc41850f005bfbf31ba70f710a71 610 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 209 602 1.0E-170 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 hmeg3_RS09510 e0badc41850f005bfbf31ba70f710a71 610 Gene3D G3DSA:3.40.640.10 236 484 1.2E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 Gene3D G3DSA:3.40.50.980 189 345 6.8E-33 T 28-03-2018 hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 SUPERFAMILY SSF56801 11 534 8.5E-135 T 28-03-2018 hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 Gene3D G3DSA:3.30.300.30 432 538 5.2E-26 T 28-03-2018 hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 Pfam PF00501 AMP-binding enzyme 20 436 2.8E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 522 4.5E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 Gene3D G3DSA:3.40.50.980 11 188 2.0E-31 T 28-03-2018 hmeg3_RS04870 2b6c78eb631b62db23b1187dcb70db4c 540 Gene3D G3DSA:2.30.38.10 346 431 9.6E-28 T 28-03-2018 hmeg3_RS17295 675093cb554beb00fc6b22feb1c76adf 203 Gene3D G3DSA:3.40.50.360 1 203 1.0E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS17295 675093cb554beb00fc6b22feb1c76adf 203 Pfam PF03358 NADPH-dependent FMN reductase 15 145 1.3E-7 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS17295 675093cb554beb00fc6b22feb1c76adf 203 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 8 200 1.7E-45 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 hmeg3_RS17295 675093cb554beb00fc6b22feb1c76adf 203 ProSitePatterns PS00201 Flavodoxin signature. 11 27 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 hmeg3_RS17295 675093cb554beb00fc6b22feb1c76adf 203 SUPERFAMILY SSF52218 8 200 1.09E-60 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS05630 32718519511e528db9f5456951117c61 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 hmeg3_RS05630 32718519511e528db9f5456951117c61 389 Gene3D G3DSA:3.90.1150.10 1 142 4.5E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS05630 32718519511e528db9f5456951117c61 389 Gene3D G3DSA:3.90.1150.10 201 388 4.8E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS05630 32718519511e528db9f5456951117c61 389 SUPERFAMILY SSF53383 6 387 1.5E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS05630 32718519511e528db9f5456951117c61 389 Pfam PF00155 Aminotransferase class I and II 34 382 7.4E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS12175 24cb902e60789bbde1c2663d4d9a3a4f 152 Gene3D G3DSA:3.10.450.50 26 148 9.3E-17 T 28-03-2018 hmeg3_RS12175 24cb902e60789bbde1c2663d4d9a3a4f 152 Pfam PF14534 Domain of unknown function (DUF4440) 35 139 8.7E-15 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 hmeg3_RS12175 24cb902e60789bbde1c2663d4d9a3a4f 152 SUPERFAMILY SSF54427 29 145 2.74E-22 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS21765 faec7fb0f5c9ea557b85cee4b823b430 304 SUPERFAMILY SSF53335 91 280 5.88E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS21765 faec7fb0f5c9ea557b85cee4b823b430 304 PIRSF PIRSF000401 1 303 3.1E-96 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 hmeg3_RS21765 faec7fb0f5c9ea557b85cee4b823b430 304 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 301 31.468 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 hmeg3_RS21765 faec7fb0f5c9ea557b85cee4b823b430 304 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 300 8.2E-90 T 28-03-2018 hmeg3_RS21765 faec7fb0f5c9ea557b85cee4b823b430 304 Gene3D G3DSA:3.40.50.150 106 301 3.0E-35 T 28-03-2018 hmeg3_RS21765 faec7fb0f5c9ea557b85cee4b823b430 304 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 295 2.8E-71 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 hmeg3_RS01350 ad24efe7765155c559af7571c3854316 307 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 159 174 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site hmeg3_RS01350 ad24efe7765155c559af7571c3854316 307 Gene3D G3DSA:3.40.50.1820 37 241 2.2E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01350 ad24efe7765155c559af7571c3854316 307 Pfam PF07859 alpha/beta hydrolase fold 95 212 5.8E-13 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS01350 ad24efe7765155c559af7571c3854316 307 SUPERFAMILY SSF53474 35 290 5.17E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09980 80c6cef784b4fd1b61934a14b2e4c3c9 171 Pfam PF03938 Outer membrane protein (OmpH-like) 16 169 7.7E-33 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 hmeg3_RS09980 80c6cef784b4fd1b61934a14b2e4c3c9 171 Gene3D G3DSA:3.30.910.20 18 170 1.9E-22 T 28-03-2018 hmeg3_RS09980 80c6cef784b4fd1b61934a14b2e4c3c9 171 SUPERFAMILY SSF111384 29 169 1.57E-33 T 28-03-2018 IPR024930 Skp domain hmeg3_RS09980 80c6cef784b4fd1b61934a14b2e4c3c9 171 PIRSF PIRSF002094 5 171 4.0E-48 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 hmeg3_RS09980 80c6cef784b4fd1b61934a14b2e4c3c9 171 SMART SM00935 18 170 3.3E-55 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 hmeg3_RS03965 47d10de439e08acf2522e7340ab55b18 292 Pfam PF10503 Esterase PHB depolymerase 37 163 2.1E-5 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 hmeg3_RS03965 47d10de439e08acf2522e7340ab55b18 292 Gene3D G3DSA:3.40.50.1820 20 291 7.1E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS03965 47d10de439e08acf2522e7340ab55b18 292 SUPERFAMILY SSF53474 30 282 5.22E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02630 38ea2081b1737c51c5b280d83d681317 308 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 38.067 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 hmeg3_RS02630 38ea2081b1737c51c5b280d83d681317 308 Pfam PF04381 Putative exonuclease, RdgC 1 295 1.2E-121 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 hmeg3_RS17435 95d35e8d85997d35dfe9fce2f396839d 267 Gene3D G3DSA:3.40.190.10 21 174 1.2E-12 T 28-03-2018 hmeg3_RS17435 95d35e8d85997d35dfe9fce2f396839d 267 Gene3D G3DSA:3.40.190.10 175 257 2.4E-5 T 28-03-2018 hmeg3_RS17435 95d35e8d85997d35dfe9fce2f396839d 267 SUPERFAMILY SSF53850 26 253 1.26E-21 T 28-03-2018 hmeg3_RS17435 95d35e8d85997d35dfe9fce2f396839d 267 SMART SM00062 40 253 7.2E-4 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS17435 95d35e8d85997d35dfe9fce2f396839d 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 60 251 5.2E-16 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Gene3D G3DSA:1.10.287.130 238 295 3.1E-12 T 28-03-2018 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 297 2.6E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Pfam PF08521 Two-component sensor kinase N-terminal 17 153 1.3E-31 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 SUPERFAMILY SSF55874 288 451 2.62E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 5.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 451 2.9E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 SUPERFAMILY SSF47384 217 299 1.02E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Gene3D G3DSA:1.20.5.1040 3 55 0.0042 T 28-03-2018 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Gene3D G3DSA:3.30.450.20 61 237 9.9E-4 T 28-03-2018 hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 SMART SM00387 344 453 4.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 Gene3D G3DSA:3.30.565.10 306 456 4.6E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07120 3198023bd2385dd315e8016c292e34a6 457 SMART SM00388 233 299 5.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 Gene3D G3DSA:3.40.50.10090 2 49 6.7E-10 T 28-03-2018 hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 Gene3D G3DSA:3.40.50.720 50 254 8.3E-62 T 28-03-2018 hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 1.1E-54 T 28-03-2018 hmeg3_RS04110 b26fc9dc15257cc5ef19b26730fa21fb 254 SUPERFAMILY SSF51735 6 253 2.03E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 Pfam PF07690 Major Facilitator Superfamily 253 425 4.4E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 Gene3D G3DSA:1.20.1250.20 12 220 2.5E-27 T 28-03-2018 hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 SUPERFAMILY SSF103473 17 424 1.44E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 Gene3D G3DSA:1.20.1250.20 221 430 3.6E-22 T 28-03-2018 hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 25 411 2.4E-136 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 hmeg3_RS07405 a35e52e4faf6ae6b1d3fad8d2a17f3ef 431 Pfam PF00083 Sugar (and other) transporter 21 216 3.9E-26 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 hmeg3_RS06830 baf5deb3c1e456ebfe6c7dec57837ea7 356 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 348 1.2E-162 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 hmeg3_RS06830 baf5deb3c1e456ebfe6c7dec57837ea7 356 PIRSF PIRSF001361 1 350 7.9E-158 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 hmeg3_RS06830 baf5deb3c1e456ebfe6c7dec57837ea7 356 Pfam PF00793 DAHP synthetase I family 40 333 5.5E-102 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 hmeg3_RS06830 baf5deb3c1e456ebfe6c7dec57837ea7 356 SUPERFAMILY SSF51569 6 347 1.57E-134 T 28-03-2018 hmeg3_RS06830 baf5deb3c1e456ebfe6c7dec57837ea7 356 Gene3D G3DSA:3.20.20.70 7 353 5.2E-129 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 SMART SM00448 8 118 7.4E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 Pfam PF00072 Response regulator receiver domain 10 119 2.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 SMART SM00862 159 235 5.6E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 235 1.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 SUPERFAMILY SSF52172 4 134 1.85E-42 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 Gene3D G3DSA:1.10.10.10 134 241 2.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 SUPERFAMILY SSF46894 136 236 3.12E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS15980 87e91c676134c000c71b1bc94356d841 245 Gene3D G3DSA:3.40.50.2300 5 133 2.6E-39 T 28-03-2018 hmeg3_RS13385 b7cde9838b281b261db75e205cdc259e 188 SUPERFAMILY SSF52218 9 174 3.71E-28 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS13385 b7cde9838b281b261db75e205cdc259e 188 Gene3D G3DSA:3.40.50.360 6 187 3.8E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS13385 b7cde9838b281b261db75e205cdc259e 188 Pfam PF03358 NADPH-dependent FMN reductase 9 143 5.3E-26 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS23255 e106e877bdec34bc688466adf7876d51 536 SUPERFAMILY SSF51905 480 530 7.13E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23255 e106e877bdec34bc688466adf7876d51 536 SUPERFAMILY SSF51905 102 288 7.13E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23255 e106e877bdec34bc688466adf7876d51 536 Gene3D G3DSA:3.50.50.60 87 535 1.6E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23255 e106e877bdec34bc688466adf7876d51 536 Pfam PF01593 Flavin containing amine oxidoreductase 215 270 3.4E-4 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 hmeg3_RS23255 e106e877bdec34bc688466adf7876d51 536 PIRSF PIRSF038984 1 536 2.6E-240 T 28-03-2018 IPR028348 FAD dependent protein hmeg3_RS18715 22b1201e6cf765f3c1245c8b7cba9f93 145 Pfam PF01878 EVE domain 4 132 4.9E-13 T 28-03-2018 IPR002740 EVE domain hmeg3_RS18715 22b1201e6cf765f3c1245c8b7cba9f93 145 Gene3D G3DSA:3.10.590.10 2 135 3.6E-9 T 28-03-2018 hmeg3_RS18715 22b1201e6cf765f3c1245c8b7cba9f93 145 Hamap MF_00771 UPF0310 protein . 2 134 24.069 T 28-03-2018 IPR022996 Uncharacterised protein family UPF0310 hmeg3_RS18715 22b1201e6cf765f3c1245c8b7cba9f93 145 SUPERFAMILY SSF88697 5 134 1.69E-22 T 28-03-2018 IPR015947 PUA-like domain hmeg3_RS24240 a8c2c48cc96ae1fe61290ab317f46677 678 Pfam PF05170 AsmA family 182 553 5.9E-69 T 28-03-2018 IPR007844 AsmA hmeg3_RS24240 a8c2c48cc96ae1fe61290ab317f46677 678 Pfam PF05170 AsmA family 10 149 8.4E-27 T 28-03-2018 IPR007844 AsmA hmeg3_RS19200 50eda76a22b5062f8580dfb46c85e16a 235 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 207 2.1E-16 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS19200 50eda76a22b5062f8580dfb46c85e16a 235 SUPERFAMILY SSF53681 153 208 5.56E-5 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS19200 50eda76a22b5062f8580dfb46c85e16a 235 Gene3D G3DSA:3.40.50.1860 6 112 1.5E-5 T 28-03-2018 hmeg3_RS19200 50eda76a22b5062f8580dfb46c85e16a 235 Gene3D G3DSA:3.40.50.1860 113 202 2.9E-15 T 28-03-2018 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 SUPERFAMILY SSF52317 1 194 3.12E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 SUPERFAMILY SSF46689 213 262 6.81E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 Gene3D G3DSA:1.10.10.60 267 321 8.2E-9 T 28-03-2018 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 Gene3D G3DSA:1.10.10.60 213 240 1.9E-5 T 28-03-2018 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 Pfam PF01965 DJ-1/PfpI family 2 173 1.2E-22 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 SMART SM00342 229 312 6.4E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 SUPERFAMILY SSF46689 265 316 4.18E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 Gene3D G3DSA:3.40.50.880 1 212 4.8E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 Gene3D G3DSA:1.10.260.40 241 266 3.6E-7 T 28-03-2018 hmeg3_RS01655 74af7f0e35a7f81b6ef499a9b0006b59 344 Pfam PF12833 Helix-turn-helix domain 235 314 3.6E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS13960 2509bb56977865104a6c971503925623 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 395 542 1.9E-45 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 hmeg3_RS13960 2509bb56977865104a6c971503925623 572 Gene3D G3DSA:3.40.50.970 1 194 6.2E-65 T 28-03-2018 hmeg3_RS13960 2509bb56977865104a6c971503925623 572 SUPERFAMILY SSF52518 3 186 1.14E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS13960 2509bb56977865104a6c971503925623 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 1.6E-59 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 hmeg3_RS13960 2509bb56977865104a6c971503925623 572 SUPERFAMILY SSF52467 190 363 2.29E-63 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS13960 2509bb56977865104a6c971503925623 572 SUPERFAMILY SSF52518 373 567 1.97E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS13960 2509bb56977865104a6c971503925623 572 Gene3D G3DSA:3.40.50.1220 195 355 2.2E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS13960 2509bb56977865104a6c971503925623 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 6 566 6.4E-250 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 hmeg3_RS13960 2509bb56977865104a6c971503925623 572 Gene3D G3DSA:3.40.50.970 356 565 5.0E-48 T 28-03-2018 hmeg3_RS13960 2509bb56977865104a6c971503925623 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 332 2.6E-45 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 hmeg3_RS03655 4a9182596a394fcd6f930af6d0cddf42 361 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 160 173 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 hmeg3_RS03655 4a9182596a394fcd6f930af6d0cddf42 361 TIGRFAM TIGR04048 nitrile_sll0784: putative nitrilase, sll0784 family 6 305 1.6E-173 T 28-03-2018 IPR023919 Nitrilase-related, sll0784 hmeg3_RS03655 4a9182596a394fcd6f930af6d0cddf42 361 Pfam PF00795 Carbon-nitrogen hydrolase 9 281 3.5E-58 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS03655 4a9182596a394fcd6f930af6d0cddf42 361 SUPERFAMILY SSF56317 6 301 1.31E-78 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS03655 4a9182596a394fcd6f930af6d0cddf42 361 Gene3D G3DSA:3.60.110.10 1 308 5.0E-68 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 193 0.0032 T 28-03-2018 hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 SUPERFAMILY SSF51735 13 252 5.04E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 5.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 5.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 252 3.9E-62 T 28-03-2018 hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 Gene3D G3DSA:3.40.50.720 55 253 2.4E-62 T 28-03-2018 hmeg3_RS04425 6d62a8733175fd134c9f0e585ae23c21 253 Gene3D G3DSA:3.40.50.10090 6 54 2.0E-10 T 28-03-2018 hmeg3_RS01190 ff01acc08975cd2ffeae9bfc26bb8f77 342 Gene3D G3DSA:2.102.10.10 4 106 7.6E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01190 ff01acc08975cd2ffeae9bfc26bb8f77 342 SUPERFAMILY SSF50022 4 112 8.51E-32 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01190 ff01acc08975cd2ffeae9bfc26bb8f77 342 SUPERFAMILY SSF55961 116 334 6.41E-33 T 28-03-2018 hmeg3_RS01190 ff01acc08975cd2ffeae9bfc26bb8f77 342 Gene3D G3DSA:3.90.380.10 107 342 2.6E-35 T 28-03-2018 hmeg3_RS01190 ff01acc08975cd2ffeae9bfc26bb8f77 342 Pfam PF00355 Rieske [2Fe-2S] domain 6 88 1.9E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 Gene3D G3DSA:3.40.190.10 175 262 1.2E-25 T 28-03-2018 hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 2.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 Pfam PF03466 LysR substrate binding domain 89 290 2.3E-44 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 SUPERFAMILY SSF46785 3 112 6.09E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 Gene3D G3DSA:1.10.10.10 1 85 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 SUPERFAMILY SSF53850 90 290 1.05E-42 T 28-03-2018 hmeg3_RS08940 a2db565442dd21e78f466652651ffd8e 293 Gene3D G3DSA:3.40.190.10 90 174 4.2E-15 T 28-03-2018 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 Gene3D G3DSA:3.40.50.300 1 79 7.6E-9 T 28-03-2018 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 PIRSF PIRSF006641 1 363 2.6E-149 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.062 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 Gene3D G3DSA:1.10.150.300 110 200 7.0E-27 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 4.6E-153 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 Pfam PF01926 50S ribosome-binding GTPase 5 122 1.9E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 6.8E-38 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 SUPERFAMILY SSF52540 3 300 3.66E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.7E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.7E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.7E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.7E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 Gene3D G3DSA:3.10.20.30 263 362 4.5E-44 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS03420 aa73bbfc257d7b7592286ae5ff2d28e4 363 SUPERFAMILY SSF81271 279 359 7.85E-35 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 hmeg3_RS23145 5a48e13e9cce3fcc1e98636f46d809c4 300 Gene3D G3DSA:1.10.3720.10 19 288 6.1E-43 T 28-03-2018 hmeg3_RS23145 5a48e13e9cce3fcc1e98636f46d809c4 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 63 1.3E-5 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS23145 5a48e13e9cce3fcc1e98636f46d809c4 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 297 2.5E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23145 5a48e13e9cce3fcc1e98636f46d809c4 300 SUPERFAMILY SSF161098 94 284 1.02E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 SUPERFAMILY SSF56935 22 347 1.74E-69 T 28-03-2018 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00184 Neisseria sp. porin signature 181 198 3.6E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00184 Neisseria sp. porin signature 285 309 3.6E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00184 Neisseria sp. porin signature 54 79 3.6E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00184 Neisseria sp. porin signature 151 168 3.6E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 Pfam PF13609 Gram-negative porin 14 313 3.0E-51 T 28-03-2018 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 Gene3D G3DSA:2.40.160.10 10 347 1.5E-64 T 28-03-2018 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 180 192 9.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 266 283 9.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 9.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 96 106 9.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19230 d9dfecae76fffb7c8896cc663938ea37 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 152 163 9.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21775 ef6c3a2f8b3b1cb80c56fe496cc4ad93 311 Gene3D G3DSA:3.40.1190.20 1 308 2.8E-50 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS21775 ef6c3a2f8b3b1cb80c56fe496cc4ad93 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 hmeg3_RS21775 ef6c3a2f8b3b1cb80c56fe496cc4ad93 311 Pfam PF00294 pfkB family carbohydrate kinase 32 294 1.5E-39 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB hmeg3_RS21775 ef6c3a2f8b3b1cb80c56fe496cc4ad93 311 SUPERFAMILY SSF53613 4 297 9.82E-61 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 SMART SM00344 4 113 6.8E-45 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 SUPERFAMILY SSF46785 3 62 3.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 SUPERFAMILY SSF54909 66 153 2.55E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 Pfam PF01037 Lrp/AsnC ligand binding domain 70 144 3.1E-21 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 3.0E-18 T 28-03-2018 hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 Gene3D G3DSA:1.10.10.10 1 55 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 Gene3D G3DSA:3.30.70.920 57 150 2.0E-25 T 28-03-2018 hmeg3_RS22535 e37b394a827588de53e12ae4f8ad7178 154 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.2E-15 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.2E-15 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.2E-15 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 Gene3D G3DSA:4.10.520.10 1 94 4.1E-35 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 SMART SM00411 1 90 3.5E-39 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 SUPERFAMILY SSF47729 1 91 2.36E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS22060 fb265d52e7137101525ef6189c176abc 94 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.6E-33 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS07660 bebbc87372252de0c122db43c16489f1 118 Pfam PF16786 Recombination enhancement, RecA-dependent nuclease 9 100 8.3E-23 T 28-03-2018 IPR031875 Recombination enhancement, RecA-dependent nuclease hmeg3_RS00195 94a6976b4b19b1f5c8714d9e5f8cf9ff 366 SMART SM00062 80 297 1.6E-13 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS00195 94a6976b4b19b1f5c8714d9e5f8cf9ff 366 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 82 361 9.6E-62 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 hmeg3_RS00195 94a6976b4b19b1f5c8714d9e5f8cf9ff 366 Pfam PF13379 NMT1-like family 80 302 4.9E-15 T 28-03-2018 hmeg3_RS00195 94a6976b4b19b1f5c8714d9e5f8cf9ff 366 SUPERFAMILY SSF53850 78 309 2.9E-44 T 28-03-2018 hmeg3_RS00195 94a6976b4b19b1f5c8714d9e5f8cf9ff 366 Gene3D G3DSA:3.40.190.10 76 172 3.7E-15 T 28-03-2018 hmeg3_RS00195 94a6976b4b19b1f5c8714d9e5f8cf9ff 366 Gene3D G3DSA:3.40.190.10 173 305 1.7E-26 T 28-03-2018 hmeg3_RS23730 bebad0f278a79d4e5bff6b654dfcff3a 168 Gene3D G3DSA:3.40.630.30 1 89 2.4E-10 T 28-03-2018 hmeg3_RS23730 bebad0f278a79d4e5bff6b654dfcff3a 168 Gene3D G3DSA:3.40.630.30 90 158 5.6E-18 T 28-03-2018 hmeg3_RS23730 bebad0f278a79d4e5bff6b654dfcff3a 168 Pfam PF00583 Acetyltransferase (GNAT) family 38 140 9.7E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS23730 bebad0f278a79d4e5bff6b654dfcff3a 168 SUPERFAMILY SSF55729 5 167 4.39E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS22790 8a00e5f4ef71c29b8338c8c1a25e11f3 131 Gene3D G3DSA:3.30.1490.10 75 130 3.5E-22 T 28-03-2018 hmeg3_RS22790 8a00e5f4ef71c29b8338c8c1a25e11f3 131 SUPERFAMILY SSF56047 2 130 2.62E-47 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22790 8a00e5f4ef71c29b8338c8c1a25e11f3 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.442 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22790 8a00e5f4ef71c29b8338c8c1a25e11f3 131 Gene3D G3DSA:3.30.1370.30 1 67 4.2E-26 T 28-03-2018 hmeg3_RS22790 8a00e5f4ef71c29b8338c8c1a25e11f3 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22790 8a00e5f4ef71c29b8338c8c1a25e11f3 131 Pfam PF00410 Ribosomal protein S8 5 130 1.9E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 SUPERFAMILY SSF46689 235 281 2.82E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 Gene3D G3DSA:1.10.10.60 191 236 5.5E-8 T 28-03-2018 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 SUPERFAMILY SSF46689 185 230 6.9E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 SMART SM00342 199 281 1.2E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 Pfam PF12833 Helix-turn-helix domain 205 281 3.2E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 Pfam PF02311 AraC-like ligand binding domain 38 149 2.0E-18 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 236 277 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 SUPERFAMILY SSF51215 37 152 1.44E-17 T 28-03-2018 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 Gene3D G3DSA:1.10.10.60 237 283 1.0E-11 T 28-03-2018 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 265 281 4.0E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 265 4.0E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 hmeg3_RS04615 63e4a3d60931bdb36409e573e0cfa33b 284 Gene3D G3DSA:2.60.120.280 29 190 1.5E-15 T 28-03-2018 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 254 3.6E-93 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 Gene3D G3DSA:3.90.230.10 2 262 1.7E-86 T 28-03-2018 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 Hamap MF_01974 Methionine aminopeptidase [map]. 4 256 40.921 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 198 210 4.8E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 97 113 4.8E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 4.8E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 75 88 4.8E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 SUPERFAMILY SSF55920 4 257 5.5E-91 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS09930 4a5e8788200dba675bc3b110db9f3267 274 Pfam PF00557 Metallopeptidase family M24 13 247 1.9E-53 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS21205 4c27238a3c605692b1d10c427216b6d1 290 SUPERFAMILY SSF53335 96 262 5.5E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS21205 4c27238a3c605692b1d10c427216b6d1 290 TIGRFAM TIGR04325 MTase_LIC12133: putative methyltransferase, LIC12133 family 44 288 2.1E-58 T 28-03-2018 IPR027612 Putative methyltransferase, LIC12133 family hmeg3_RS21205 4c27238a3c605692b1d10c427216b6d1 290 Gene3D G3DSA:3.40.50.150 27 252 3.1E-5 T 28-03-2018 hmeg3_RS24215 bd6e9f9034ab12447d169bad1fcf2b30 256 SMART SM00382 30 223 3.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24215 bd6e9f9034ab12447d169bad1fcf2b30 256 Gene3D G3DSA:3.40.50.300 1 251 6.5E-55 T 28-03-2018 hmeg3_RS24215 bd6e9f9034ab12447d169bad1fcf2b30 256 SUPERFAMILY SSF52540 4 247 5.22E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24215 bd6e9f9034ab12447d169bad1fcf2b30 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 3.2E-8 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS24215 bd6e9f9034ab12447d169bad1fcf2b30 256 Pfam PF00005 ABC transporter 22 177 8.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 PIRSF PIRSF003165 1 161 4.8E-52 T 28-03-2018 IPR016379 Type III secretion system, low calcium response, chaperone LcrH/SycD, subgroup hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 Gene3D G3DSA:1.25.40.10 2 153 4.1E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 73 95 4.7E-16 T 28-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 24 47 4.7E-16 T 28-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 49 68 4.7E-16 T 28-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 105 127 4.7E-16 T 28-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 Pfam PF07720 Tetratricopeptide repeat 38 70 1.5E-11 T 28-03-2018 IPR011716 Tetratricopeptide TPR-3 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 Pfam PF07720 Tetratricopeptide repeat 73 99 3.9E-4 T 28-03-2018 IPR011716 Tetratricopeptide TPR-3 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 SUPERFAMILY SSF48452 29 141 9.99E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS15780 79dd34feecca7d20f28923625334897d 171 TIGRFAM TIGR02552 LcrH_SycD: type III secretion low calcium response chaperone LcrH/SycD 22 150 5.8E-35 T 28-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 hmeg3_RS23005 a3cfad19565f4f67b6a62b8ce7b61a14 519 TIGRFAM TIGR00836 amt: ammonium transporter 89 517 2.9E-131 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 hmeg3_RS23005 a3cfad19565f4f67b6a62b8ce7b61a14 519 SUPERFAMILY SSF111352 86 498 3.27E-124 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 hmeg3_RS23005 a3cfad19565f4f67b6a62b8ce7b61a14 519 Gene3D G3DSA:1.10.3430.10 82 498 1.7E-130 T 28-03-2018 hmeg3_RS23005 a3cfad19565f4f67b6a62b8ce7b61a14 519 Pfam PF00909 Ammonium Transporter Family 91 517 5.5E-120 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 hmeg3_RS23005 a3cfad19565f4f67b6a62b8ce7b61a14 519 ProSitePatterns PS01219 Ammonium transporters signature. 265 290 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 hmeg3_RS06185 19c2ef82179dcdcd7819bb63518b7ce6 281 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 14 275 6.4E-79 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 hmeg3_RS06185 19c2ef82179dcdcd7819bb63518b7ce6 281 Gene3D G3DSA:1.10.3720.10 4 272 4.1E-36 T 28-03-2018 hmeg3_RS06185 19c2ef82179dcdcd7819bb63518b7ce6 281 SUPERFAMILY SSF161098 26 270 3.18E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS06185 19c2ef82179dcdcd7819bb63518b7ce6 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 274 2.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 8.8E-170 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 SMART SM01209 101 294 2.2E-137 T 28-03-2018 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 SMART SM01210 328 420 2.5E-50 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Gene3D G3DSA:3.40.50.20 2 84 2.4E-35 T 28-03-2018 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 42.406 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 418 3.3E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 6.5E-36 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 SUPERFAMILY SSF56059 102 323 4.77E-62 T 28-03-2018 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Gene3D G3DSA:3.90.600.10 328 421 9.5E-32 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Gene3D G3DSA:3.30.1490.20 85 187 1.3E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Gene3D G3DSA:3.30.470.20 189 327 2.1E-60 T 28-03-2018 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 SUPERFAMILY SSF52440 1 101 5.18E-35 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 SUPERFAMILY SSF51246 327 420 3.82E-30 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 hmeg3_RS18810 d7759d002250e3464772702ed7d22ca1 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 294 3.4E-78 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 SMART SM00138 1 261 1.0E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 Gene3D G3DSA:1.10.155.10 2 64 2.1E-6 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 PRINTS PR00996 Glutamate methyltransferase family signature 201 215 8.4E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 PRINTS PR00996 Glutamate methyltransferase family signature 220 243 8.4E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 8.4E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 PRINTS PR00996 Glutamate methyltransferase family signature 98 118 8.4E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 PRINTS PR00996 Glutamate methyltransferase family signature 131 147 8.4E-20 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 SUPERFAMILY SSF48452 328 418 1.6E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 Pfam PF01739 CheR methyltransferase, SAM binding domain 68 242 1.9E-34 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 Gene3D G3DSA:1.25.40.120 293 433 3.1E-13 T 28-03-2018 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 Gene3D G3DSA:3.40.50.150 66 254 1.6E-39 T 28-03-2018 hmeg3_RS14895 e77a02b2acaea54ca0ca77d014ff73f8 434 SUPERFAMILY SSF53335 67 248 3.13E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 Pfam PF12833 Helix-turn-helix domain 187 264 6.2E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 Gene3D G3DSA:1.10.10.60 219 269 5.0E-13 T 28-03-2018 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 Pfam PF02311 AraC-like ligand binding domain 18 145 6.2E-21 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 SUPERFAMILY SSF51215 13 131 4.18E-16 T 28-03-2018 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 SMART SM00342 181 263 1.1E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 SUPERFAMILY SSF46689 217 264 1.88E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 SUPERFAMILY SSF46689 167 214 2.78E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS15400 66bfc1e6939dfdd76fcdf9616a34a636 270 Gene3D G3DSA:1.10.10.60 85 218 2.0E-12 T 28-03-2018 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 Gene3D G3DSA:3.40.50.970 62 321 1.3E-20 T 28-03-2018 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 SUPERFAMILY SSF52922 318 450 5.76E-8 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 SUPERFAMILY SSF52518 491 679 1.43E-17 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 511 661 5.7E-8 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 Gene3D G3DSA:3.40.50.970 494 685 1.7E-31 T 28-03-2018 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 Gene3D G3DSA:3.40.50.920 322 456 2.9E-9 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 788 974 5.3E-25 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 Gene3D G3DSA:3.40.920.10 779 990 3.4E-50 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 SUPERFAMILY SSF52518 94 242 2.12E-18 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS10790 48b43e7e2d41957c91175bfd93ee789d 1223 SUPERFAMILY SSF53323 780 1023 4.05E-29 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 Gene3D G3DSA:3.30.70.270 163 321 7.8E-46 T 28-03-2018 hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 SUPERFAMILY SSF55781 27 161 4.71E-26 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 Gene3D G3DSA:3.30.450.40 14 162 1.4E-22 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 SMART SM00065 26 168 1.3E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 SMART SM00267 154 321 2.4E-38 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 SUPERFAMILY SSF55073 169 319 7.3E-39 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 162 320 1.9E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 Pfam PF01590 GAF domain 27 157 6.7E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS17930 590121cb37b699c59a21e0f0bf191c2b 322 Pfam PF00990 Diguanylate cyclase, GGDEF domain 164 320 5.4E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 Gene3D G3DSA:1.10.10.60 1 58 9.4E-19 T 28-03-2018 hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 SUPERFAMILY SSF46689 2 66 1.4E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 Gene3D G3DSA:1.10.357.10 59 193 1.2E-26 T 28-03-2018 hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site hmeg3_RS13160 98f3a4f8ae17dd432c25fba27d33e762 194 SUPERFAMILY SSF48498 79 192 8.66E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 SUPERFAMILY SSF46946 134 225 4.06E-26 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 4.1E-22 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 273 40.709 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 SUPERFAMILY SSF81624 2 142 2.75E-37 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 SUPERFAMILY SSF57716 221 272 4.85E-16 T 28-03-2018 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 272 9.5E-84 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 Gene3D G3DSA:3.20.190.10 2 134 9.8E-36 T 28-03-2018 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 ProSitePatterns PS01242 Zinc finger FPG-type signature. 248 272 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 SMART SM01232 133 225 1.7E-40 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 Gene3D G3DSA:1.10.8.50 135 273 8.3E-45 T 28-03-2018 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 SMART SM00898 2 115 1.5E-44 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 hmeg3_RS04325 a415df6079607aa1f4d1acba50dc806d 273 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 7.0E-31 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 Gene3D G3DSA:3.40.50.720 143 241 1.7E-22 T 28-03-2018 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 SUPERFAMILY SSF50129 5 151 7.15E-37 T 28-03-2018 IPR011032 GroES-like hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 92 2.2E-12 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 Gene3D G3DSA:3.90.180.10 1 142 7.4E-42 T 28-03-2018 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 Gene3D G3DSA:3.90.180.10 242 310 0.059 T 28-03-2018 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 SMART SM00829 13 306 4.6E-23 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 Pfam PF13602 Zinc-binding dehydrogenase 188 306 7.5E-19 T 28-03-2018 hmeg3_RS01740 d813ef40015d7c8185324a5c24417f04 310 SUPERFAMILY SSF51735 118 245 9.87E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS03245 0b6826f7201bca2fad02dd3ca0a05966 325 Gene3D G3DSA:3.40.50.2300 29 152 8.2E-22 T 28-03-2018 hmeg3_RS03245 0b6826f7201bca2fad02dd3ca0a05966 325 Gene3D G3DSA:3.40.50.2300 153 289 1.5E-19 T 28-03-2018 hmeg3_RS03245 0b6826f7201bca2fad02dd3ca0a05966 325 SUPERFAMILY SSF53822 33 289 1.07E-22 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS03245 0b6826f7201bca2fad02dd3ca0a05966 325 Pfam PF04392 ABC transporter substrate binding protein 33 323 5.5E-111 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein hmeg3_RS20445 8a66707a6d2d5aa81191356a768ab037 108 Pfam PF01337 Barstar (barnase inhibitor) 5 96 1.4E-24 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) hmeg3_RS20445 8a66707a6d2d5aa81191356a768ab037 108 Gene3D G3DSA:3.30.370.10 1 101 2.7E-20 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) hmeg3_RS20445 8a66707a6d2d5aa81191356a768ab037 108 SUPERFAMILY SSF52038 5 86 6.67E-13 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 Pfam PF00106 short chain dehydrogenase 7 197 7.7E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 SUPERFAMILY SSF51735 4 232 4.03E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 Gene3D G3DSA:3.40.50.720 1 200 6.4E-57 T 28-03-2018 hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.3E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.3E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.3E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04005 d8e4028c432cb368ed76657bbbab168f 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS13695 b5e07fe107aa30f277e911a45118182f 136 Pfam PF13279 Thioesterase-like superfamily 15 131 4.9E-15 T 28-03-2018 hmeg3_RS13695 b5e07fe107aa30f277e911a45118182f 136 Gene3D G3DSA:3.10.129.10 4 136 2.2E-34 T 28-03-2018 hmeg3_RS13695 b5e07fe107aa30f277e911a45118182f 136 SUPERFAMILY SSF54637 7 135 4.27E-35 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS19920 083b7bb1aac8571127ab8395c4731278 236 SUPERFAMILY SSF53448 1 231 1.15E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS19920 083b7bb1aac8571127ab8395c4731278 236 Gene3D G3DSA:3.90.550.10 1 236 1.5E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS19920 083b7bb1aac8571127ab8395c4731278 236 Pfam PF00483 Nucleotidyl transferase 2 118 5.2E-20 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS21450 bd65db7339b523b761d394a4afb37f0f 248 SUPERFAMILY SSF102405 26 223 2.75E-59 T 28-03-2018 hmeg3_RS21450 bd65db7339b523b761d394a4afb37f0f 248 Gene3D G3DSA:3.40.50.450 27 240 2.1E-67 T 28-03-2018 hmeg3_RS21450 bd65db7339b523b761d394a4afb37f0f 248 Pfam PF03641 Possible lysine decarboxylase 93 221 7.7E-33 T 28-03-2018 IPR031100 LOG family hmeg3_RS21450 bd65db7339b523b761d394a4afb37f0f 248 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 51 225 3.3E-41 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG hmeg3_RS04590 266c217f36da8646470dfa9679efc96d 303 SUPERFAMILY SSF161098 94 285 1.31E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04590 266c217f36da8646470dfa9679efc96d 303 Gene3D G3DSA:1.10.3720.10 27 302 4.8E-45 T 28-03-2018 hmeg3_RS04590 266c217f36da8646470dfa9679efc96d 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 58 7.6E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS04590 266c217f36da8646470dfa9679efc96d 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 300 1.2E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 Gene3D G3DSA:1.20.120.530 74 219 4.6E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 3.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 Pfam PF07729 FCD domain 80 201 4.8E-15 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 Gene3D G3DSA:1.10.10.10 2 73 7.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 SUPERFAMILY SSF48008 75 208 3.66E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 SMART SM00345 12 70 2.2E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 SMART SM00895 80 202 3.4E-6 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS23705 3d0d9ef72e6aa8c067a5739d968b8894 228 SUPERFAMILY SSF46785 7 74 2.17E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10380 efc7b9e3ee13dd827ec3ecd61610169c 455 Gene3D G3DSA:3.50.50.60 2 455 5.1E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10380 efc7b9e3ee13dd827ec3ecd61610169c 455 Pfam PF01593 Flavin containing amine oxidoreductase 21 452 5.8E-24 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 hmeg3_RS10380 efc7b9e3ee13dd827ec3ecd61610169c 455 SUPERFAMILY SSF51905 415 452 2.63E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10380 efc7b9e3ee13dd827ec3ecd61610169c 455 SUPERFAMILY SSF51905 12 317 2.63E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10380 efc7b9e3ee13dd827ec3ecd61610169c 455 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 13 453 2.1E-123 T 28-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 ProSitePatterns PS00211 ABC transporters family signature. 837 851 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 SUPERFAMILY SSF52540 623 920 4.89E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 SUPERFAMILY SSF52540 1 206 1.75E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 SUPERFAMILY SSF52540 438 577 1.75E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 Gene3D G3DSA:3.40.50.300 1 141 3.4E-18 T 28-03-2018 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 Gene3D G3DSA:1.10.8.280 291 409 5.5E-35 T 28-03-2018 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 Gene3D G3DSA:3.40.50.300 421 621 1.2E-23 T 28-03-2018 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 Gene3D G3DSA:3.30.190.20 142 252 4.3E-42 T 28-03-2018 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 932 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 947 22.228 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 Gene3D G3DSA:3.40.50.300 622 951 2.4E-55 T 28-03-2018 hmeg3_RS04075 bfc6d2f803293b29711c330905184721 951 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06740 d04f72ad1e8082c2e9eb5387429201d3 380 Pfam PF02653 Branched-chain amino acid transport system / permease component 71 343 1.9E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06740 d04f72ad1e8082c2e9eb5387429201d3 380 Gene3D G3DSA:1.10.3470.10 16 356 4.0E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 Gene3D G3DSA:3.30.565.10 375 533 1.1E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 SUPERFAMILY SSF55874 361 529 6.02E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 SMART SM00387 412 527 3.0E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 SUPERFAMILY SSF47384 268 368 3.53E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 469 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 412 526 3.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 Pfam PF05227 CHASE3 domain 36 170 7.6E-7 T 28-03-2018 IPR007891 CHASE3 hmeg3_RS18620 926e7893eecb75d5d3a90f6ae427ed08 543 Gene3D G3DSA:1.10.287.130 273 367 6.9E-10 T 28-03-2018 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 Gene3D G3DSA:3.40.50.80 214 348 5.0E-21 T 28-03-2018 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 145 155 2.8E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 161 168 2.8E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 221 240 2.8E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 246 255 2.8E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 313 321 2.8E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 Pfam PF00175 Oxidoreductase NAD-binding domain 222 326 1.7E-18 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 Gene3D G3DSA:2.40.30.10 121 213 1.0E-17 T 28-03-2018 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 SUPERFAMILY SSF50022 1 105 1.83E-30 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 SUPERFAMILY SSF52343 214 346 2.36E-34 T 28-03-2018 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 Pfam PF00355 Rieske [2Fe-2S] domain 4 90 2.6E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 SUPERFAMILY SSF63380 116 212 4.26E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 Gene3D G3DSA:2.102.10.10 1 120 1.2E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 Pfam PF00970 Oxidoreductase FAD-binding domain 121 212 4.3E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 157 7.7E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 221 240 7.7E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 246 255 7.7E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 161 168 7.7E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 206 215 7.7E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS01315 5129a3ff9418eda0c62bff546b773d09 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 313 321 7.7E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 SUPERFAMILY SSF46785 893 958 1.14E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 SMART SM00843 893 958 5.1E-38 T 28-03-2018 IPR018541 FtsK gamma domain hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 Pfam PF01580 FtsK/SpoIIIE family 579 789 9.1E-66 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 Gene3D G3DSA:1.10.10.10 895 949 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 Pfam PF09397 Ftsk gamma domain 895 955 1.3E-25 T 28-03-2018 IPR018541 FtsK gamma domain hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 Gene3D G3DSA:3.40.50.300 572 829 2.8E-56 T 28-03-2018 hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 SUPERFAMILY SSF52540 557 861 3.05E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12285 95ad09b69c1f568da0891ac18cb0a662 961 SMART SM00382 615 810 0.0076 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 Pfam PF02253 Phospholipase A1 220 437 1.5E-39 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 PRINTS PR01486 Bacterial phospholipase A1 protein signature 265 284 5.6E-16 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 PRINTS PR01486 Bacterial phospholipase A1 protein signature 409 429 5.6E-16 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 PRINTS PR01486 Bacterial phospholipase A1 protein signature 218 235 5.6E-16 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 PRINTS PR01486 Bacterial phospholipase A1 protein signature 348 366 5.6E-16 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 Gene3D G3DSA:2.40.230.10 193 439 3.8E-60 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS17325 7e42d8d9d04c5c59a30e06785da8a29c 439 SUPERFAMILY SSF56931 197 438 1.23E-58 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Gene3D G3DSA:2.40.50.140 56 140 3.9E-5 T 28-03-2018 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SUPERFAMILY SSF50249 59 136 1.04E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Gene3D G3DSA:1.10.10.10 8 55 2.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 TIGRFAM TIGR02063 RNase_R: ribonuclease R 9 584 4.3E-203 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 65 739 2.8E-207 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SUPERFAMILY SSF50249 658 738 9.36E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Pfam PF08206 Ribonuclease B OB domain 76 133 1.3E-22 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Hamap MF_01895 Ribonuclease R [rnr]. 27 739 55.02 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SMART SM00955 248 580 1.5E-181 T 28-03-2018 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Pfam PF00575 S1 RNA binding domain 655 736 4.1E-11 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Gene3D G3DSA:2.40.50.140 655 740 2.3E-18 T 28-03-2018 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SMART SM00316 656 739 3.0E-13 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SMART SM00316 69 131 13.0 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 Pfam PF00773 RNB domain 248 578 7.7E-104 T 28-03-2018 hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 ProSitePatterns PS01175 Ribonuclease II family signature. 547 571 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SUPERFAMILY SSF50249 175 490 7.2E-139 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SUPERFAMILY SSF50249 526 581 7.2E-139 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SUPERFAMILY SSF50249 616 656 7.2E-139 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08965 a1a99624f6dd4abff58d6e07ec75cc97 838 SMART SM00357 75 134 3.1E-15 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 251 1.0E-93 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 Hamap MF_01974 Methionine aminopeptidase [map]. 5 252 40.472 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 Gene3D G3DSA:3.90.230.10 1 261 2.1E-84 T 28-03-2018 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 Pfam PF00557 Metallopeptidase family M24 15 243 7.1E-54 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 4.3E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 4.3E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 4.3E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 4.3E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 hmeg3_RS12755 3cefccc7a80ad17082d242511ee50267 264 SUPERFAMILY SSF55920 6 255 1.44E-92 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS09360 511e23318b8df041d7a33e11680f933f 344 Gene3D G3DSA:3.40.190.10 149 285 1.1E-29 T 28-03-2018 hmeg3_RS09360 511e23318b8df041d7a33e11680f933f 344 SUPERFAMILY SSF53850 29 335 4.64E-70 T 28-03-2018 hmeg3_RS09360 511e23318b8df041d7a33e11680f933f 344 PIRSF PIRSF002825 1 338 1.1E-90 T 28-03-2018 IPR026045 Ferric binding protein hmeg3_RS09360 511e23318b8df041d7a33e11680f933f 344 Pfam PF13343 Bacterial extracellular solute-binding protein 79 303 1.2E-29 T 28-03-2018 hmeg3_RS09360 511e23318b8df041d7a33e11680f933f 344 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 24 342 2.3E-159 T 28-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative hmeg3_RS09360 511e23318b8df041d7a33e11680f933f 344 Gene3D G3DSA:3.40.190.10 20 148 3.9E-13 T 28-03-2018 hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 Gene3D G3DSA:3.40.50.1100 226 418 2.1E-38 T 28-03-2018 hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 108 122 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 81 405 3.1E-45 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 29 418 51.554 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 Gene3D G3DSA:3.40.50.1100 36 225 5.1E-43 T 28-03-2018 hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 34 417 9.0E-190 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 SUPERFAMILY SSF53686 30 415 1.19E-148 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS17215 20a2923cb08dee2177a0dbfd891c2256 419 PIRSF PIRSF001413 17 419 3.2E-163 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS10995 523197702470c276128de9321e053d18 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS10995 523197702470c276128de9321e053d18 432 Gene3D G3DSA:1.20.1250.20 13 223 3.3E-24 T 28-03-2018 hmeg3_RS10995 523197702470c276128de9321e053d18 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS10995 523197702470c276128de9321e053d18 432 Pfam PF00083 Sugar (and other) transporter 21 421 1.6E-31 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 hmeg3_RS10995 523197702470c276128de9321e053d18 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 312 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS10995 523197702470c276128de9321e053d18 432 SUPERFAMILY SSF103473 18 424 2.35E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10995 523197702470c276128de9321e053d18 432 Gene3D G3DSA:1.20.1250.20 224 427 7.1E-21 T 28-03-2018 hmeg3_RS06095 9e32fab7edd543c35897a1c123a9168e 271 Gene3D G3DSA:1.10.3720.10 14 264 3.2E-25 T 28-03-2018 hmeg3_RS06095 9e32fab7edd543c35897a1c123a9168e 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 254 1.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS06095 9e32fab7edd543c35897a1c123a9168e 271 SUPERFAMILY SSF161098 65 251 2.22E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09485 9cf397c31f9b4809f110a6c7764cf6b2 244 SUPERFAMILY SSF161098 46 227 7.72E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09485 9cf397c31f9b4809f110a6c7764cf6b2 244 Gene3D G3DSA:1.10.3720.10 44 241 4.4E-24 T 28-03-2018 hmeg3_RS09485 9cf397c31f9b4809f110a6c7764cf6b2 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 239 6.9E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21260 ce22444d5da7ffd8ae48159562ca86eb 183 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 174 8.5E-49 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 hmeg3_RS21260 ce22444d5da7ffd8ae48159562ca86eb 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 21 174 7.0E-58 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 hmeg3_RS21260 ce22444d5da7ffd8ae48159562ca86eb 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 1.3E-59 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 hmeg3_RS21260 ce22444d5da7ffd8ae48159562ca86eb 183 Gene3D G3DSA:2.60.120.10 1 181 1.2E-61 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS21260 ce22444d5da7ffd8ae48159562ca86eb 183 SUPERFAMILY SSF51182 1 178 1.94E-64 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS09785 e4245cdd0774b0a0bbf64ca23c56263c 348 Pfam PF08907 Domain of unknown function (DUF1853) 46 329 4.0E-77 T 28-03-2018 IPR015003 Protein of unknown function DUF1853 hmeg3_RS05850 46bb276edf3642289d972c4348fcd658 375 Pfam PF01266 FAD dependent oxidoreductase 6 368 1.5E-64 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS05850 46bb276edf3642289d972c4348fcd658 375 Gene3D G3DSA:3.40.50.720 3 94 2.2E-9 T 28-03-2018 hmeg3_RS05850 46bb276edf3642289d972c4348fcd658 375 Gene3D G3DSA:3.30.9.10 95 202 4.1E-19 T 28-03-2018 hmeg3_RS05850 46bb276edf3642289d972c4348fcd658 375 Gene3D G3DSA:3.30.9.10 205 328 1.5E-22 T 28-03-2018 hmeg3_RS05850 46bb276edf3642289d972c4348fcd658 375 SUPERFAMILY SSF51905 6 327 3.84E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16575 24a52cfddf68b82ac6687a772662a0c6 171 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 158 22.398 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS16575 24a52cfddf68b82ac6687a772662a0c6 171 SUPERFAMILY SSF52121 10 158 2.35E-45 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS16575 24a52cfddf68b82ac6687a772662a0c6 171 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 152 1.6E-35 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS16575 24a52cfddf68b82ac6687a772662a0c6 171 Gene3D G3DSA:3.40.50.960 13 167 7.6E-46 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 Pfam PF01327 Polypeptide deformylase 4 159 6.2E-48 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 Gene3D G3DSA:3.90.45.10 1 168 5.1E-55 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 Hamap MF_00163 Peptide deformylase [def]. 2 171 26.275 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 SUPERFAMILY SSF56420 2 166 7.85E-56 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 PRINTS PR01576 Peptide deformylase signature 34 63 9.1E-28 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 PRINTS PR01576 Peptide deformylase signature 98 109 9.1E-28 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 PRINTS PR01576 Peptide deformylase signature 110 128 9.1E-28 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 PRINTS PR01576 Peptide deformylase signature 129 158 9.1E-28 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 PIRSF PIRSF004749 1 171 3.0E-46 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS09895 d5461599339bda26b3a83db4bb08718a 178 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 6.1E-34 T 28-03-2018 IPR023635 Peptide deformylase hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 275 6.5E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 525 557 2.3E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 SMART SM00382 331 523 4.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 SMART SM00382 29 227 3.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 ProSitePatterns PS00211 ABC transporters family signature. 446 460 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 Pfam PF00005 ABC transporter 20 177 2.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 Pfam PF00005 ABC transporter 323 473 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 SUPERFAMILY SSF52540 4 248 1.63E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 SUPERFAMILY SSF52540 302 545 1.28E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 Gene3D G3DSA:3.40.50.300 299 568 4.5E-79 T 28-03-2018 hmeg3_RS23130 74818f2a32438f8ec217541344ea35d5 571 Gene3D G3DSA:3.40.50.300 1 284 4.0E-70 T 28-03-2018 hmeg3_RS20615 263977fef8f7a0ddae4ed5d28318feca 542 Pfam PF03961 Flagellar Assembly Protein A 84 537 2.9E-103 T 28-03-2018 IPR005646 Flagellar assembly protein A hmeg3_RS20615 263977fef8f7a0ddae4ed5d28318feca 542 SUPERFAMILY SSF63848 280 324 2.75E-5 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 hmeg3_RS20615 263977fef8f7a0ddae4ed5d28318feca 542 Gene3D G3DSA:2.160.20.70 263 350 6.4E-11 T 28-03-2018 hmeg3_RS20510 0a32225995ddf1ad65f5d9982be6092a 413 Pfam PF01170 Putative RNA methylase family UPF0020 173 391 1.4E-45 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS20510 0a32225995ddf1ad65f5d9982be6092a 413 SMART SM00981 67 165 3.1E-17 T 28-03-2018 IPR004114 THUMP domain GO:0003723 hmeg3_RS20510 0a32225995ddf1ad65f5d9982be6092a 413 Gene3D G3DSA:3.40.50.150 104 386 3.9E-29 T 28-03-2018 hmeg3_RS20510 0a32225995ddf1ad65f5d9982be6092a 413 Pfam PF02926 THUMP domain 52 163 1.9E-9 T 28-03-2018 IPR004114 THUMP domain GO:0003723 hmeg3_RS20510 0a32225995ddf1ad65f5d9982be6092a 413 SUPERFAMILY SSF53335 264 392 1.42E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20510 0a32225995ddf1ad65f5d9982be6092a 413 SUPERFAMILY SSF53335 158 228 1.42E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS00100 d4f5f0440889048f96c26f4dab4575eb 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 274 6.5E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00100 d4f5f0440889048f96c26f4dab4575eb 286 SUPERFAMILY SSF161098 81 262 4.19E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00100 d4f5f0440889048f96c26f4dab4575eb 286 Gene3D G3DSA:1.10.3720.10 33 277 5.5E-26 T 28-03-2018 hmeg3_RS05280 b5c7b3a35371ea24a2b0738458ed2e07 193 Gene3D G3DSA:1.10.10.10 39 190 2.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05280 b5c7b3a35371ea24a2b0738458ed2e07 193 SUPERFAMILY SSF46785 47 183 3.38E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05280 b5c7b3a35371ea24a2b0738458ed2e07 193 Pfam PF13463 Winged helix DNA-binding domain 75 140 6.1E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS05280 b5c7b3a35371ea24a2b0738458ed2e07 193 PIRSF PIRSF036158 3 193 2.2E-69 T 28-03-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain hmeg3_RS19675 692892b243d25fe066d2bcadd6f34744 202 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 198 19.921 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 hmeg3_RS19675 692892b243d25fe066d2bcadd6f34744 202 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 199 5.9E-58 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 hmeg3_RS19675 692892b243d25fe066d2bcadd6f34744 202 SMART SM01207 8 190 2.3E-81 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 hmeg3_RS19675 692892b243d25fe066d2bcadd6f34744 202 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 189 2.9E-49 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 hmeg3_RS14460 0d0f1dd84d218ccde17a71ddb9236fa9 286 Gene3D G3DSA:1.10.3720.10 38 283 3.2E-26 T 28-03-2018 hmeg3_RS14460 0d0f1dd84d218ccde17a71ddb9236fa9 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 276 2.0E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14460 0d0f1dd84d218ccde17a71ddb9236fa9 286 SUPERFAMILY SSF161098 85 268 1.2E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 Gene3D G3DSA:3.90.226.10 23 321 1.6E-65 T 28-03-2018 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 8 319 49.299 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 9.2E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 9.2E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 9.2E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 9.2E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 9.2E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 9.2E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 SUPERFAMILY SSF52096 9 319 4.54E-100 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 9 151 1.2E-65 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS09015 81dc7b6e0dd4c5885c81489eaf968802 326 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 6 321 1.6E-149 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 hmeg3_RS02045 368effa81d8abb0373ca8f257b6e64d5 346 Gene3D G3DSA:3.40.50.880 89 345 7.1E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS02045 368effa81d8abb0373ca8f257b6e64d5 346 Pfam PF07722 Peptidase C26 106 318 2.2E-53 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 hmeg3_RS02045 368effa81d8abb0373ca8f257b6e64d5 346 SUPERFAMILY SSF52317 138 343 8.36E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS22125 a77529bfb3e5418e0f4c50091e8bf593 251 SUPERFAMILY SSF51621 1 246 2.3E-65 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS22125 a77529bfb3e5418e0f4c50091e8bf593 251 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 238 3.1E-32 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 hmeg3_RS22125 a77529bfb3e5418e0f4c50091e8bf593 251 Gene3D G3DSA:3.20.20.60 1 251 5.8E-41 T 28-03-2018 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 SUPERFAMILY SSF51395 10 319 3.3E-88 T 28-03-2018 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 Gene3D G3DSA:1.10.1200.80 252 330 6.9E-24 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 49.165 T 28-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 Pfam PF01207 Dihydrouridine synthase (Dus) 14 316 1.7E-104 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 PIRSF PIRSF006621 2 328 3.2E-104 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 Gene3D G3DSA:3.20.20.70 8 240 7.6E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS21655 6fda03d5ad3113cc1282ea668d08b132 338 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 5.4E-120 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 hmeg3_RS05725 607d49abfe9be8c1b2f7376cf0ca66d6 178 SUPERFAMILY SSF52980 2 176 3.49E-74 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 hmeg3_RS05725 607d49abfe9be8c1b2f7376cf0ca66d6 178 Pfam PF07152 YaeQ protein 1 172 2.1E-80 T 28-03-2018 IPR009822 YaeQ hmeg3_RS05725 607d49abfe9be8c1b2f7376cf0ca66d6 178 SMART SM01322 1 175 1.2E-120 T 28-03-2018 IPR009822 YaeQ hmeg3_RS05725 607d49abfe9be8c1b2f7376cf0ca66d6 178 PIRSF PIRSF011484 1 178 3.4E-76 T 28-03-2018 IPR009822 YaeQ hmeg3_RS05725 607d49abfe9be8c1b2f7376cf0ca66d6 178 Gene3D G3DSA:3.10.640.10 1 173 1.5E-81 T 28-03-2018 hmeg3_RS17710 65831b1afc608495527e435b5472b7ee 501 Pfam PF02321 Outer membrane efflux protein 89 266 5.4E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS17710 65831b1afc608495527e435b5472b7ee 501 Pfam PF02321 Outer membrane efflux protein 293 474 3.1E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS17710 65831b1afc608495527e435b5472b7ee 501 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 476 6.3E-107 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS17710 65831b1afc608495527e435b5472b7ee 501 SUPERFAMILY SSF56954 74 480 3.92E-102 T 28-03-2018 hmeg3_RS17710 65831b1afc608495527e435b5472b7ee 501 SUPERFAMILY SSF56954 9 40 3.92E-102 T 28-03-2018 hmeg3_RS17710 65831b1afc608495527e435b5472b7ee 501 Gene3D G3DSA:1.20.1600.10 31 481 1.1E-91 T 28-03-2018 hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 Pfam PF00501 AMP-binding enzyme 28 446 4.7E-89 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 Gene3D G3DSA:2.30.38.10 352 438 1.0E-18 T 28-03-2018 hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 Gene3D G3DSA:3.40.50.980 193 351 3.9E-36 T 28-03-2018 hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 Gene3D G3DSA:3.40.50.980 17 192 5.3E-33 T 28-03-2018 hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 537 1.4E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 Gene3D G3DSA:3.30.300.30 439 548 2.6E-24 T 28-03-2018 hmeg3_RS14870 215f6a9bca44bcbd5e5332ae9551308c 549 SUPERFAMILY SSF56801 13 548 3.53E-132 T 28-03-2018 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 SUPERFAMILY SSF52540 90 371 1.9E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 SMART SM00382 170 349 1.5E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 SUPERFAMILY SSF68912 1 46 1.02E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.2E-14 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 SMART SM00959 5 47 4.6E-16 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 Gene3D G3DSA:3.40.50.300 129 419 1.9E-56 T 28-03-2018 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 242.946 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.3E-30 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 6.1E-209 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 SUPERFAMILY SSF50249 49 125 2.06E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 SMART SM00357 52 118 1.6E-15 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.1E-23 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS19535 f390f73fa26b0e42b63aecebe9a56a80 420 Gene3D G3DSA:2.40.50.140 2 126 1.1E-42 T 28-03-2018 hmeg3_RS23370 dbf7dc3376404ff0eef698be56a05186 138 SUPERFAMILY SSF54427 16 131 7.56E-28 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS23370 dbf7dc3376404ff0eef698be56a05186 138 Pfam PF12680 SnoaL-like domain 19 123 1.3E-22 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS23370 dbf7dc3376404ff0eef698be56a05186 138 Gene3D G3DSA:3.10.450.50 15 134 5.9E-27 T 28-03-2018 hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 Gene3D G3DSA:3.40.50.300 4 334 4.1E-80 T 28-03-2018 hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 331 2.3E-30 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 SUPERFAMILY SSF52540 53 325 7.28E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 Pfam PF00005 ABC transporter 44 195 2.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 SMART SM00382 53 245 3.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11100 10ee0d77f960f1dc85c18e2b5237b0a7 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 5.8E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS19860 32b574b36fda1527d82029da6ff87e4a 222 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 39 182 3.2E-33 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 hmeg3_RS19860 32b574b36fda1527d82029da6ff87e4a 222 Gene3D G3DSA:3.40.50.1000 38 217 2.1E-34 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS19860 32b574b36fda1527d82029da6ff87e4a 222 PIRSF PIRSF004682 33 216 1.9E-51 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 hmeg3_RS19860 32b574b36fda1527d82029da6ff87e4a 222 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 40 183 1.5E-45 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 hmeg3_RS19860 32b574b36fda1527d82029da6ff87e4a 222 SUPERFAMILY SSF56784 35 214 1.38E-44 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS19860 32b574b36fda1527d82029da6ff87e4a 222 Pfam PF08645 Polynucleotide kinase 3 phosphatase 49 151 1.0E-9 T 28-03-2018 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 hmeg3_RS22965 0152b8f5df0d93a1572048afcde45672 422 SUPERFAMILY SSF103473 8 410 4.32E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS22965 0152b8f5df0d93a1572048afcde45672 422 Gene3D G3DSA:1.20.1250.20 2 210 8.5E-19 T 28-03-2018 hmeg3_RS22965 0152b8f5df0d93a1572048afcde45672 422 Gene3D G3DSA:1.20.1250.20 215 417 5.5E-17 T 28-03-2018 hmeg3_RS22965 0152b8f5df0d93a1572048afcde45672 422 Pfam PF07690 Major Facilitator Superfamily 20 368 1.2E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS00810 5c0a738867fa4373292c89e9203313df 264 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS00810 5c0a738867fa4373292c89e9203313df 264 SUPERFAMILY SSF52540 4 247 3.77E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00810 5c0a738867fa4373292c89e9203313df 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 1.3E-8 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS00810 5c0a738867fa4373292c89e9203313df 264 SMART SM00382 30 225 4.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00810 5c0a738867fa4373292c89e9203313df 264 Pfam PF00005 ABC transporter 21 178 9.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00810 5c0a738867fa4373292c89e9203313df 264 Gene3D G3DSA:3.40.50.300 2 264 3.0E-59 T 28-03-2018 hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 201 1.7E-4 T 28-03-2018 hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 260 7.9E-59 T 28-03-2018 hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 SUPERFAMILY SSF51735 18 261 1.66E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 6.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 6.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 6.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 6.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 6.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 6.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 6.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 6.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 6.8E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15080 70f27da668c95a20939d376e298c2642 263 Gene3D G3DSA:3.40.50.720 2 263 1.2E-69 T 28-03-2018 hmeg3_RS01855 e15760d970dd48ecea485068906b4b2f 101 SUPERFAMILY SSF54909 8 66 9.12E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS04985 cc8d042ec8fe1f19fa89f7932a6f22ef 200 SUPERFAMILY SSF64438 23 172 2.29E-49 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic hmeg3_RS04985 cc8d042ec8fe1f19fa89f7932a6f22ef 200 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 18 173 28.787 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 hmeg3_RS04985 cc8d042ec8fe1f19fa89f7932a6f22ef 200 Pfam PF03975 CheD chemotactic sensory transduction 65 169 2.1E-32 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 hmeg3_RS17495 fad7c731d7f8ce4b5106959d2ae97e7b 157 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 7 148 2.1E-21 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 Gene3D G3DSA:3.40.630.10 7 258 4.7E-41 T 28-03-2018 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 Gene3D G3DSA:3.40.630.10 259 416 5.6E-22 T 28-03-2018 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 Pfam PF07687 Peptidase dimerisation domain 218 315 6.4E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 15 411 3.2E-123 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 SUPERFAMILY SSF55031 218 334 8.2E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 SUPERFAMILY SSF53187 6 228 5.14E-93 T 28-03-2018 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 SUPERFAMILY SSF53187 341 413 5.14E-93 T 28-03-2018 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 PIRSF PIRSF001235 9 418 1.4E-128 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 hmeg3_RS00800 3aaad43387bfff4c674b34a9a29cb769 418 Pfam PF01546 Peptidase family M20/M25/M40 86 411 3.9E-35 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS12040 21bef1eaf559e8d970c58b3ae2f4bd8d 156 PIRSF PIRSF033736 19 156 9.0E-30 T 28-03-2018 IPR017021 Uncharacterised conserved protein UCP033763 hmeg3_RS12040 21bef1eaf559e8d970c58b3ae2f4bd8d 156 SUPERFAMILY SSF102462 25 155 1.05E-29 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 hmeg3_RS12040 21bef1eaf559e8d970c58b3ae2f4bd8d 156 Pfam PF09391 Protein of unknown function (DUF2000) 25 156 5.3E-39 T 28-03-2018 IPR018988 Protein of unknown function DUF2000 hmeg3_RS12040 21bef1eaf559e8d970c58b3ae2f4bd8d 156 Gene3D G3DSA:3.40.1490.10 25 154 9.6E-38 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 Pfam PF01799 [2Fe-2S] binding domain 75 147 8.1E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 SUPERFAMILY SSF54292 2 80 6.16E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 Gene3D G3DSA:1.10.150.120 77 156 2.3E-32 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 SUPERFAMILY SSF47741 86 153 2.36E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 Gene3D G3DSA:3.10.20.30 1 76 1.4E-26 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS15615 9be02e537aabb4de03f80e790d6c7c95 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 56 2.6E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 Pfam PF00155 Aminotransferase class I and II 141 450 7.6E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 1.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 Gene3D G3DSA:1.10.10.10 4 79 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 SUPERFAMILY SSF46785 9 81 1.25E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 Gene3D G3DSA:3.90.1150.10 337 467 2.3E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 SMART SM00345 18 77 1.9E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 Gene3D G3DSA:3.40.640.10 135 336 9.0E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS13455 24f471dd4eb5e0311e3bdbdf86817aa9 467 SUPERFAMILY SSF53383 108 465 2.02E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 108 118 4.8E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 163 174 4.8E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 65 76 4.8E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 313 330 4.8E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 SUPERFAMILY SSF56935 31 369 1.25E-66 T 28-03-2018 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 Pfam PF13609 Gram-negative porin 20 339 4.5E-43 T 28-03-2018 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00184 Neisseria sp. porin signature 310 334 2.8E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00184 Neisseria sp. porin signature 162 179 2.8E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 PRINTS PR00184 Neisseria sp. porin signature 67 92 2.8E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS18970 cecdfa2dc666de3e0e1455f8391b7612 369 Gene3D G3DSA:2.40.160.10 19 369 4.5E-55 T 28-03-2018 hmeg3_RS03940 057218bc7f344a22b37e03b1f60b7f7b 378 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 132 353 2.6E-11 T 28-03-2018 IPR005079 Peptidase C45 hmeg3_RS03940 057218bc7f344a22b37e03b1f60b7f7b 378 Gene3D G3DSA:3.60.60.10 114 372 3.6E-26 T 28-03-2018 hmeg3_RS09070 a55ca9636b4f7e8012119fb8bc0b12f9 486 SUPERFAMILY SSF58113 103 218 9.94E-5 T 28-03-2018 hmeg3_RS09070 a55ca9636b4f7e8012119fb8bc0b12f9 486 Pfam PF02646 RmuC family 177 467 2.3E-81 T 28-03-2018 IPR003798 DNA recombination RmuC hmeg3_RS09070 a55ca9636b4f7e8012119fb8bc0b12f9 486 Gene3D G3DSA:1.20.120.20 26 214 3.5E-7 T 28-03-2018 hmeg3_RS09070 a55ca9636b4f7e8012119fb8bc0b12f9 486 Gene3D G3DSA:1.20.1480.30 366 460 0.0017 T 28-03-2018 hmeg3_RS08525 bc7d26b9f528c1fbaddd897d3a22377a 280 Pfam PF12710 haloacid dehalogenase-like hydrolase 77 244 9.1E-15 T 28-03-2018 hmeg3_RS08525 bc7d26b9f528c1fbaddd897d3a22377a 280 SUPERFAMILY SSF56784 72 279 1.76E-44 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS08525 bc7d26b9f528c1fbaddd897d3a22377a 280 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 72 278 1.2E-67 T 28-03-2018 hmeg3_RS08525 bc7d26b9f528c1fbaddd897d3a22377a 280 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 75 244 8.0E-31 T 28-03-2018 hmeg3_RS08525 bc7d26b9f528c1fbaddd897d3a22377a 280 Gene3D G3DSA:3.40.50.1000 133 279 3.8E-20 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS08525 bc7d26b9f528c1fbaddd897d3a22377a 280 Gene3D G3DSA:1.10.150.210 86 132 5.2E-23 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 hmeg3_RS17585 61215b47b1795a469d93f289f047c0dd 264 SMART SM00062 36 257 3.9E-66 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS17585 61215b47b1795a469d93f289f047c0dd 264 Gene3D G3DSA:3.40.190.10 25 179 5.7E-45 T 28-03-2018 hmeg3_RS17585 61215b47b1795a469d93f289f047c0dd 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 255 4.3E-65 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS17585 61215b47b1795a469d93f289f047c0dd 264 SUPERFAMILY SSF53850 5 256 1.23E-66 T 28-03-2018 hmeg3_RS17585 61215b47b1795a469d93f289f047c0dd 264 SMART SM00079 36 256 0.0026 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS17585 61215b47b1795a469d93f289f047c0dd 264 Gene3D G3DSA:3.40.190.10 180 254 6.3E-9 T 28-03-2018 hmeg3_RS11255 9681c250020280ccb07fa8f7c6d9ab12 211 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 31 210 5.5E-83 T 28-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 hmeg3_RS11255 9681c250020280ccb07fa8f7c6d9ab12 211 SUPERFAMILY SSF81452 27 208 3.14E-57 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11255 9681c250020280ccb07fa8f7c6d9ab12 211 Pfam PF00510 Cytochrome c oxidase subunit III 28 208 2.6E-15 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11255 9681c250020280ccb07fa8f7c6d9ab12 211 Gene3D G3DSA:1.20.120.80 25 210 1.8E-50 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS22440 4ee0497203842c43ec83994f832050b9 487 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 410 430 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22440 4ee0497203842c43ec83994f832050b9 487 Pfam PF00474 Sodium:solute symporter family 32 428 1.9E-47 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS14245 db832256e3788c18b3135657cd03d015 234 SUPERFAMILY SSF52540 2 231 1.36E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14245 db832256e3788c18b3135657cd03d015 234 SMART SM00382 26 212 2.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14245 db832256e3788c18b3135657cd03d015 234 Pfam PF00005 ABC transporter 17 161 2.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14245 db832256e3788c18b3135657cd03d015 234 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS14245 db832256e3788c18b3135657cd03d015 234 Gene3D G3DSA:3.40.50.300 1 234 3.1E-56 T 28-03-2018 hmeg3_RS14245 db832256e3788c18b3135657cd03d015 234 PIRSF PIRSF039137 1 234 5.9E-106 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 SMART SM00387 346 459 1.4E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 Gene3D G3DSA:1.10.287.130 225 297 2.7E-12 T 28-03-2018 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 SUPERFAMILY SSF55874 290 450 1.44E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 SMART SM00304 181 234 1.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 2.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 2.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 2.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 3 454 1.5E-127 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 Gene3D G3DSA:3.30.565.10 309 456 3.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 SMART SM00388 235 301 2.9E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 SUPERFAMILY SSF158472 184 231 5.23E-5 T 28-03-2018 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 301 6.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 453 1.2E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 Pfam PF00672 HAMP domain 181 230 9.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05650 3b5de6d24ca29ebf846935dc6b0cf178 460 SUPERFAMILY SSF47384 218 301 1.69E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82693 137 182 8.55E-20 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82693 280 336 8.55E-20 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82693 804 849 4.88E-10 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82693 674 715 4.88E-10 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82714 719 800 4.97E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Pfam PF00873 AcrB/AcrD/AcrF family 4 1024 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82866 302 502 9.42E-47 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82714 183 266 1.44E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82693 568 663 1.67E-10 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Gene3D G3DSA:3.30.2090.10 715 806 6.8E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Gene3D G3DSA:3.30.2090.10 181 269 1.5E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82693 40 132 5.06E-22 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Gene3D G3DSA:1.20.1640.10 817 1038 4.0E-34 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Gene3D G3DSA:1.20.1640.10 293 515 1.9E-46 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Gene3D G3DSA:3.30.70.1430 40 142 8.5E-25 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 Gene3D G3DSA:3.30.70.1430 570 666 3.7E-10 T 28-03-2018 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 369 390 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 555 572 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 618 632 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 475 498 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 342 365 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 450 473 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 PRINTS PR00702 Acriflavin resistance protein family signature 397 421 5.7E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05660 9163a506e40030ac096a204c7d2f35f5 1055 SUPERFAMILY SSF82866 829 1026 1.57E-41 T 28-03-2018 hmeg3_RS17850 990e78b32cd4a587de2f2aac4a8ec98d 616 SUPERFAMILY SSF143975 4 420 4.97E-148 T 28-03-2018 hmeg3_RS17850 990e78b32cd4a587de2f2aac4a8ec98d 616 SUPERFAMILY SSF52016 421 602 2.04E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS17850 990e78b32cd4a587de2f2aac4a8ec98d 616 Pfam PF00920 Dehydratase family 68 599 8.6E-166 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17850 990e78b32cd4a587de2f2aac4a8ec98d 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 156 166 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS17850 990e78b32cd4a587de2f2aac4a8ec98d 616 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 5 604 2.0E-301 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 hmeg3_RS17850 990e78b32cd4a587de2f2aac4a8ec98d 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 1.0E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 1.0E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 89 1.0E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 1.0E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 Pfam PF01047 MarR family 58 113 3.6E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 Gene3D G3DSA:1.10.10.10 7 160 3.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 SUPERFAMILY SSF46785 23 159 2.66E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01075 bd4bb94fabd3b54b16f0b1bf2728145d 164 SMART SM00347 49 149 5.7E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS02820 0b265117404b187391b0da1777dfa2d6 299 Hamap MF_00082_B Acetylglutamate kinase [argB]. 30 298 35.302 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS02820 0b265117404b187391b0da1777dfa2d6 299 Pfam PF00696 Amino acid kinase family 32 275 3.6E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS02820 0b265117404b187391b0da1777dfa2d6 299 PIRSF PIRSF000728 17 298 2.7E-101 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS02820 0b265117404b187391b0da1777dfa2d6 299 TIGRFAM TIGR00761 argB: acetylglutamate kinase 33 273 3.7E-73 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 hmeg3_RS02820 0b265117404b187391b0da1777dfa2d6 299 SUPERFAMILY SSF53633 15 298 1.7E-87 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS02820 0b265117404b187391b0da1777dfa2d6 299 Gene3D G3DSA:3.40.1160.10 4 299 4.9E-69 T 28-03-2018 hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 Pfam PF07729 FCD domain 100 219 9.1E-28 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 SMART SM00895 99 221 9.2E-25 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.0E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 SUPERFAMILY SSF48008 97 228 2.62E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 Gene3D G3DSA:1.10.10.10 1 75 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 Gene3D G3DSA:1.20.120.530 77 239 1.3E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 SUPERFAMILY SSF46785 8 78 1.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17400 c01616b2a94c0cdd1d885c0f8b39d331 239 SMART SM00345 15 74 6.2E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS10595 2928efe8918910d8cdbcbe7023d072d1 246 SUPERFAMILY SSF52540 44 245 1.24E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10595 2928efe8918910d8cdbcbe7023d072d1 246 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS10595 2928efe8918910d8cdbcbe7023d072d1 246 Pfam PF00005 ABC transporter 49 195 9.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10595 2928efe8918910d8cdbcbe7023d072d1 246 SMART SM00382 58 245 2.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10595 2928efe8918910d8cdbcbe7023d072d1 246 Gene3D G3DSA:3.40.50.300 17 246 2.6E-60 T 28-03-2018 hmeg3_RS01965 2bb562126f7518594603f9455a044b21 309 Gene3D G3DSA:3.90.25.10 169 204 5.4E-6 T 28-03-2018 hmeg3_RS01965 2bb562126f7518594603f9455a044b21 309 Gene3D G3DSA:3.40.50.720 1 168 4.0E-17 T 28-03-2018 hmeg3_RS01965 2bb562126f7518594603f9455a044b21 309 Gene3D G3DSA:3.90.25.10 205 278 9.0E-21 T 28-03-2018 hmeg3_RS01965 2bb562126f7518594603f9455a044b21 309 Pfam PF04321 RmlD substrate binding domain 2 298 1.0E-95 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 hmeg3_RS01965 2bb562126f7518594603f9455a044b21 309 SUPERFAMILY SSF51735 1 298 1.74E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01965 2bb562126f7518594603f9455a044b21 309 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 297 1.9E-94 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 SUPERFAMILY SSF88659 92 180 3.18E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 Gene3D G3DSA:1.10.10.10 81 184 5.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 Pfam PF08281 Sigma-70, region 4 122 162 1.0E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 Pfam PF04542 Sigma-70 region 2 18 81 3.3E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 SUPERFAMILY SSF88946 8 95 1.37E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 Gene3D G3DSA:1.10.1740.10 2 80 1.8E-16 T 28-03-2018 hmeg3_RS24375 3be94d0050adb3697b9cb73db4c4c097 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 178 7.2E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS10355 71d4028f96783537d3e3158b1fc22016 748 Gene3D G3DSA:2.170.130.10 39 172 3.4E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10355 71d4028f96783537d3e3158b1fc22016 748 Pfam PF00593 TonB dependent receptor 290 741 1.6E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10355 71d4028f96783537d3e3158b1fc22016 748 Gene3D G3DSA:2.40.170.20 173 748 6.0E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10355 71d4028f96783537d3e3158b1fc22016 748 Pfam PF07715 TonB-dependent Receptor Plug Domain 79 180 1.2E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS10355 71d4028f96783537d3e3158b1fc22016 748 SUPERFAMILY SSF56935 43 745 5.72E-115 T 28-03-2018 hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 Gene3D G3DSA:1.10.150.240 29 100 3.6E-33 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 11 263 2.3E-107 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 SUPERFAMILY SSF56784 11 262 9.05E-55 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 Gene3D G3DSA:3.40.50.1000 101 270 1.8E-20 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 275 124.892 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 210 1.4E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS12340 d71f85774cdd6f4258cb31810e496059 275 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 209 7.5E-10 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 7.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 7.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 7.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 4.2E-59 T 28-03-2018 hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 SUPERFAMILY SSF51735 6 248 8.61E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 182 2.0E-4 T 28-03-2018 hmeg3_RS22285 4c1c06a9f50e1ff49afe7a746abe401e 251 Gene3D G3DSA:3.40.50.720 1 250 1.0E-68 T 28-03-2018 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 Gene3D G3DSA:3.40.50.1820 158 419 3.5E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01225 63db63afba6240155f529687dc394059 420 SUPERFAMILY SSF69118 7 136 1.24E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 125 3.9E-14 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 PRINTS PR00111 Alpha/beta hydrolase fold signature 262 275 2.8E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 219 2.8E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 PRINTS PR00111 Alpha/beta hydrolase fold signature 248 261 2.8E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 PRINTS PR00111 Alpha/beta hydrolase fold signature 363 377 2.8E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 SUPERFAMILY SSF53474 163 417 6.85E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01225 63db63afba6240155f529687dc394059 420 Gene3D G3DSA:1.20.1290.10 19 127 5.4E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS01225 63db63afba6240155f529687dc394059 420 Pfam PF00561 alpha/beta hydrolase fold 181 404 1.6E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 SUPERFAMILY SSF118215 9 406 8.63E-111 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 Gene3D G3DSA:1.10.3860.10 1 412 2.9E-110 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 Pfam PF00375 Sodium:dicarboxylate symporter family 10 405 2.3E-106 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 52 72 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 150 172 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS09180 a4e3a4f22162e7a18f05c5c7378a1363 432 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 1.1E-35 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 117 233 2.0E-45 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 SUPERFAMILY SSF55973 117 234 2.98E-49 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 PIRSF PIRSF000497 1 386 2.9E-171 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 384 1.1E-182 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 SUPERFAMILY SSF55973 235 385 1.81E-69 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 SUPERFAMILY SSF55973 4 111 7.06E-46 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 1.3E-40 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 385 56.705 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Gene3D G3DSA:3.30.300.10 12 129 2.5E-43 T 28-03-2018 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 374 9.1E-69 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Gene3D G3DSA:3.30.300.10 248 387 1.7E-49 T 28-03-2018 hmeg3_RS02875 3ea88b25a96abc89c13097a5529d7343 387 Gene3D G3DSA:3.30.300.10 130 235 3.8E-44 T 28-03-2018 hmeg3_RS08640 35b575de2a98f95c1e1f30e4efc756f4 578 SUPERFAMILY SSF53474 214 503 2.05E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS08640 35b575de2a98f95c1e1f30e4efc756f4 578 Gene3D G3DSA:3.40.50.1820 212 546 8.7E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS08640 35b575de2a98f95c1e1f30e4efc756f4 578 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 55 575 8.6E-219 T 28-03-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 hmeg3_RS08640 35b575de2a98f95c1e1f30e4efc756f4 578 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 88 254 4.2E-69 T 28-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 hmeg3_RS17090 52624592a4878c8651945dc27a4a890c 432 Gene3D G3DSA:3.20.20.140 78 372 2.2E-67 T 28-03-2018 hmeg3_RS17090 52624592a4878c8651945dc27a4a890c 432 SUPERFAMILY SSF51338 13 86 4.86E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS17090 52624592a4878c8651945dc27a4a890c 432 Gene3D G3DSA:2.30.40.10 10 77 4.4E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS17090 52624592a4878c8651945dc27a4a890c 432 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 27 426 1.1E-170 T 28-03-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 hmeg3_RS17090 52624592a4878c8651945dc27a4a890c 432 Pfam PF01979 Amidohydrolase family 67 428 1.8E-62 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS17090 52624592a4878c8651945dc27a4a890c 432 SUPERFAMILY SSF51556 70 373 1.72E-96 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 Gene3D G3DSA:3.40.190.10 177 264 1.3E-19 T 28-03-2018 hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 SUPERFAMILY SSF53850 90 296 4.65E-36 T 28-03-2018 hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 Gene3D G3DSA:3.40.190.10 92 176 5.3E-16 T 28-03-2018 hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 7.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 Pfam PF03466 LysR substrate binding domain 89 292 5.4E-36 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 Gene3D G3DSA:1.10.10.10 3 84 8.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02755 55ae27f92442680710303e6e9bacc868 298 SUPERFAMILY SSF46785 3 112 1.36E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 337 46.092 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 SUPERFAMILY SSF46589 14 99 3.77E-20 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 Pfam PF01409 tRNA synthetases class II core domain (F) 92 337 1.6E-94 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 Gene3D G3DSA:3.30.930.10 7 338 6.9E-87 T 28-03-2018 hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 1.6E-22 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 SUPERFAMILY SSF55681 92 338 4.98E-76 T 28-03-2018 hmeg3_RS07770 dd01971d7c260f800b2e1b367129d74f 338 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 337 4.1E-99 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 SUPERFAMILY SSF51905 1 121 1.91E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PIRSF PIRSF037149 1 844 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Gene3D G3DSA:3.50.50.60 124 254 2.1E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 641 762 1.3E-15 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Gene3D G3DSA:3.50.50.60 2 123 3.2E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Pfam PF04324 BFD-like [2Fe-2S] binding domain 433 480 1.8E-9 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 3 810 0.0 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.5E-9 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 1.5E-9 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.5E-9 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 1.5E-9 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 688 704 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 288 5.4E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Gene3D G3DSA:3.50.50.60 255 364 1.1E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Gene3D G3DSA:3.90.480.10 472 637 2.1E-17 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Gene3D G3DSA:3.30.413.10 640 825 7.4E-38 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 SUPERFAMILY SSF56014 642 818 5.76E-51 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 569 631 1.9E-11 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 SUPERFAMILY SSF51905 107 314 7.16E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00397 Sirohaem Fe-binding site signature 688 706 1.4E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00397 Sirohaem Fe-binding site signature 645 663 1.4E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.1E-15 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.1E-15 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 1.1E-15 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.1E-15 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.1E-15 T 28-03-2018 hmeg3_RS13190 5010418a4d4806da8726a4123f18356a 858 SUPERFAMILY SSF55124 511 650 1.5E-26 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 hmeg3_RS16520 8e53524961cff619137d50c0123c2e1d 403 SUPERFAMILY SSF56529 164 370 1.3E-23 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS16520 8e53524961cff619137d50c0123c2e1d 403 Gene3D G3DSA:3.90.850.10 87 370 3.6E-24 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS20640 db9e40cc7a07911d574d9e19515604bd 126 SUPERFAMILY SSF54593 1 125 3.81E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS20640 db9e40cc7a07911d574d9e19515604bd 126 Gene3D G3DSA:3.10.180.10 1 124 2.4E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS12795 64a0713970e44d43fee092a4d19fcd22 681 PIRSF PIRSF015380 4 680 1.3E-169 T 28-03-2018 IPR011385 Putative site-specific recombinase Gcr hmeg3_RS12795 64a0713970e44d43fee092a4d19fcd22 681 Pfam PF10136 Site-specific recombinase 16 665 5.3E-235 T 28-03-2018 IPR011385 Putative site-specific recombinase Gcr hmeg3_RS12795 64a0713970e44d43fee092a4d19fcd22 681 Gene3D G3DSA:1.20.1080.10 320 533 5.6E-42 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 hmeg3_RS09385 711ecfb41cd6e12302ee80a2d2d6dddb 118 Pfam PF13473 Cupredoxin-like domain 18 117 5.1E-29 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain hmeg3_RS09385 711ecfb41cd6e12302ee80a2d2d6dddb 118 SUPERFAMILY SSF49503 18 116 1.91E-15 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS09385 711ecfb41cd6e12302ee80a2d2d6dddb 118 Gene3D G3DSA:2.60.40.420 29 117 3.1E-5 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS04060 03953b8c2faca10a4e419f498faad48c 306 Pfam PF03547 Membrane transport protein 11 147 9.3E-11 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 hmeg3_RS04060 03953b8c2faca10a4e419f498faad48c 306 Pfam PF03547 Membrane transport protein 151 295 3.5E-12 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 Gene3D G3DSA:3.40.190.10 90 175 1.9E-14 T 28-03-2018 hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 Pfam PF03466 LysR substrate binding domain 86 292 4.3E-42 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 SUPERFAMILY SSF53850 87 292 1.55E-45 T 28-03-2018 hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 Gene3D G3DSA:1.10.10.10 3 83 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 Gene3D G3DSA:3.40.190.10 176 262 3.0E-25 T 28-03-2018 hmeg3_RS16850 e4673d6bc862508f22eff648215f61fe 295 SUPERFAMILY SSF46785 4 85 4.62E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.7E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 19 39 1.7E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 Pfam PF01926 50S ribosome-binding GTPase 19 132 2.5E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 Gene3D G3DSA:3.40.50.300 9 192 2.4E-32 T 28-03-2018 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 SUPERFAMILY SSF54814 189 304 2.09E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 TIGRFAM TIGR00436 era: GTP-binding protein Era 17 286 7.3E-79 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 SUPERFAMILY SSF52540 19 212 2.7E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 Hamap MF_00367 GTPase Era [era]. 14 303 33.423 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 177 3.2E-28 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 Pfam PF07650 KH domain 216 291 6.2E-17 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS16675 c6d917e797c175b94a752ea65596102f 304 Gene3D G3DSA:3.30.300.20 193 304 5.4E-37 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS13965 b9ffed2886c675ac849dd1dda4a41b4c 189 SUPERFAMILY SSF88946 10 82 6.67E-7 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13965 b9ffed2886c675ac849dd1dda4a41b4c 189 Gene3D G3DSA:1.10.10.10 84 185 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13965 b9ffed2886c675ac849dd1dda4a41b4c 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 182 2.2E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13965 b9ffed2886c675ac849dd1dda4a41b4c 189 SUPERFAMILY SSF88659 118 182 8.41E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS13965 b9ffed2886c675ac849dd1dda4a41b4c 189 Gene3D G3DSA:1.10.1740.10 2 83 7.4E-6 T 28-03-2018 hmeg3_RS13965 b9ffed2886c675ac849dd1dda4a41b4c 189 Pfam PF08281 Sigma-70, region 4 127 174 2.9E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS00805 b35f5f1839fbe7943386f40378a21217 234 SUPERFAMILY SSF52540 2 224 1.64E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00805 b35f5f1839fbe7943386f40378a21217 234 Pfam PF00005 ABC transporter 18 158 5.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00805 b35f5f1839fbe7943386f40378a21217 234 SMART SM00382 27 234 6.9E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00805 b35f5f1839fbe7943386f40378a21217 234 Gene3D G3DSA:3.40.50.300 1 230 1.2E-53 T 28-03-2018 hmeg3_RS00805 b35f5f1839fbe7943386f40378a21217 234 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS13635 a470ec6271cd528c43055107778615a7 697 Pfam PF00593 TonB dependent receptor 265 696 2.7E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS13635 a470ec6271cd528c43055107778615a7 697 SUPERFAMILY SSF56935 26 697 8.85E-120 T 28-03-2018 hmeg3_RS13635 a470ec6271cd528c43055107778615a7 697 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 63 696 9.1E-102 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS13635 a470ec6271cd528c43055107778615a7 697 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 158 4.5E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS13635 a470ec6271cd528c43055107778615a7 697 Gene3D G3DSA:2.40.170.20 172 697 2.6E-74 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS13635 a470ec6271cd528c43055107778615a7 697 Gene3D G3DSA:2.170.130.10 24 166 3.0E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 Pfam PF09339 IclR helix-turn-helix domain 17 65 1.6E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 Gene3D G3DSA:3.30.450.40 80 256 1.5E-45 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 SUPERFAMILY SSF46785 14 86 3.06E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 Pfam PF01614 Bacterial transcriptional regulator 132 251 9.8E-31 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 SMART SM00346 14 103 1.0E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 SUPERFAMILY SSF55781 71 256 1.05E-44 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS14495 69b7d790a9f706842107a1cbd1ba5810 264 Gene3D G3DSA:1.10.10.10 1 74 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11120 add3565b28780c72b79017a0b5301213 196 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 19 193 4.8E-65 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related hmeg3_RS11120 add3565b28780c72b79017a0b5301213 196 Pfam PF02627 Carboxymuconolactone decarboxylase family 57 133 1.0E-12 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS11120 add3565b28780c72b79017a0b5301213 196 SUPERFAMILY SSF69118 13 191 3.84E-45 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS11120 add3565b28780c72b79017a0b5301213 196 Gene3D G3DSA:1.20.1290.10 30 195 1.4E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS11120 add3565b28780c72b79017a0b5301213 196 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 75 104 2.0E-9 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 SUPERFAMILY SSF46785 2 93 5.68E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 SMART SM00344 3 112 1.9E-40 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 Gene3D G3DSA:1.10.10.10 3 54 2.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.7E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.7E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.7E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 Pfam PF01037 Lrp/AsnC ligand binding domain 69 143 3.2E-23 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 SUPERFAMILY SSF54909 63 152 5.9E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 2.5E-17 T 28-03-2018 hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site hmeg3_RS03995 a216a000848eb30cd5dac2d11d7a6305 158 Gene3D G3DSA:3.30.70.920 56 153 5.4E-27 T 28-03-2018 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 249 6.8E-26 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 137 2.4E-39 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 SUPERFAMILY SSF53738 254 353 1.02E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 200 213 2.0E-23 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 229 244 2.0E-23 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 2.0E-23 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 166 185 2.0E-23 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 362 3.4E-21 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Gene3D G3DSA:3.40.120.10 257 356 2.0E-24 T 28-03-2018 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Gene3D G3DSA:3.40.120.10 159 256 5.4E-32 T 28-03-2018 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 SUPERFAMILY SSF53738 150 251 2.32E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 SUPERFAMILY SSF53738 4 141 1.65E-43 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Gene3D G3DSA:3.40.120.10 2 158 2.2E-42 T 28-03-2018 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 370 445 6.5E-11 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 SUPERFAMILY SSF55957 363 456 7.32E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS21155 951e7dbbc206316555fa400909fc39db 457 Gene3D G3DSA:3.30.310.50 357 453 3.2E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 312 9.0E-21 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 Gene3D G3DSA:3.40.50.720 114 284 2.2E-42 T 28-03-2018 hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 SUPERFAMILY SSF51735 101 281 3.26E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 Gene3D G3DSA:3.40.50.720 1 113 1.8E-24 T 28-03-2018 hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 1.8E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 SUPERFAMILY SSF52283 1 131 3.78E-24 T 28-03-2018 hmeg3_RS17515 4bdb147d5c0d457079cbab8503b2c48e 318 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 hmeg3_RS08805 5542a9cda68a6d8060d54d1f0e76f29a 66 Pfam PF04325 Protein of unknown function (DUF465) 13 56 5.9E-9 T 28-03-2018 IPR007420 Protein of unknown function DUF465 hmeg3_RS14470 8e458e46de5791d9e9399c7313f6b318 322 Pfam PF09084 NMT1/THI5 like 65 260 6.1E-16 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS14470 8e458e46de5791d9e9399c7313f6b318 322 SMART SM00062 39 256 3.3E-20 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS14470 8e458e46de5791d9e9399c7313f6b318 322 Gene3D G3DSA:3.40.190.10 143 322 4.6E-34 T 28-03-2018 hmeg3_RS14470 8e458e46de5791d9e9399c7313f6b318 322 Gene3D G3DSA:3.40.190.10 34 142 6.3E-19 T 28-03-2018 hmeg3_RS14470 8e458e46de5791d9e9399c7313f6b318 322 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 40 320 1.8E-72 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 hmeg3_RS14470 8e458e46de5791d9e9399c7313f6b318 322 SUPERFAMILY SSF53850 39 265 1.54E-50 T 28-03-2018 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 Pfam PF00460 Flagella basal body rod protein 7 35 1.6E-6 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 Gene3D G3DSA:1.20.120.20 73 310 2.4E-4 T 28-03-2018 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 SUPERFAMILY SSF64518 125 460 2.75E-24 T 28-03-2018 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 699 750 4.6E-12 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 SUPERFAMILY SSF64518 440 752 6.54E-21 T 28-03-2018 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 5.5E-24 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 PRINTS PR01005 Flagellar hook-associated protein signature 216 234 5.5E-24 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 PRINTS PR01005 Flagellar hook-associated protein signature 359 381 5.5E-24 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 PRINTS PR01005 Flagellar hook-associated protein signature 50 72 5.5E-24 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 PRINTS PR01005 Flagellar hook-associated protein signature 157 181 5.5E-24 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 PRINTS PR01005 Flagellar hook-associated protein signature 259 281 5.5E-24 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS08235 617adfec79123fb6ba6beecdffcf2aeb 755 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 383 4.0E-81 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 hmeg3_RS14130 f0446732d4e04bc989014e08febe53cc 272 Pfam PF10670 Domain of unknown function (DUF4198) 22 248 8.6E-66 T 28-03-2018 IPR019613 Protein of unknown function DUF4198 hmeg3_RS14130 f0446732d4e04bc989014e08febe53cc 272 Gene3D G3DSA:2.60.120.380 31 124 0.079 T 28-03-2018 hmeg3_RS14130 f0446732d4e04bc989014e08febe53cc 272 Gene3D G3DSA:2.60.40.10 170 265 1.1E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS14130 f0446732d4e04bc989014e08febe53cc 272 SUPERFAMILY SSF49478 194 252 5.89E-5 T 28-03-2018 hmeg3_RS14820 69159bbf382e2b22c739a2bbd0b17a99 402 Gene3D G3DSA:1.20.1250.20 1 195 5.9E-17 T 28-03-2018 hmeg3_RS14820 69159bbf382e2b22c739a2bbd0b17a99 402 SUPERFAMILY SSF103473 9 390 2.75E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS14820 69159bbf382e2b22c739a2bbd0b17a99 402 Pfam PF07690 Major Facilitator Superfamily 26 344 1.4E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS14820 69159bbf382e2b22c739a2bbd0b17a99 402 Gene3D G3DSA:1.20.1250.20 196 402 1.2E-12 T 28-03-2018 hmeg3_RS22970 fde0fa9ac4087e6255da7fe161eb5bc1 200 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 10 198 9.3E-73 T 28-03-2018 IPR010743 Methionine biosynthesis MetW hmeg3_RS22970 fde0fa9ac4087e6255da7fe161eb5bc1 200 Gene3D G3DSA:3.40.50.150 5 189 5.8E-21 T 28-03-2018 hmeg3_RS22970 fde0fa9ac4087e6255da7fe161eb5bc1 200 Pfam PF07021 Methionine biosynthesis protein MetW 10 197 6.5E-69 T 28-03-2018 IPR010743 Methionine biosynthesis MetW hmeg3_RS22970 fde0fa9ac4087e6255da7fe161eb5bc1 200 SUPERFAMILY SSF53335 12 190 1.61E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS03185 5fc401e7c174402238c80a23068b8e0c 184 Pfam PF04351 Pilus assembly protein, PilP 35 179 2.2E-30 T 28-03-2018 IPR007446 Pilus assembly protein PilP hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 SUPERFAMILY SSF55874 361 507 2.1E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 Gene3D G3DSA:3.30.565.10 371 509 1.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 Gene3D G3DSA:1.10.287.130 291 370 4.7E-8 T 28-03-2018 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 8.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 8.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 507 8.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 463 8.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 SMART SM00304 248 300 2.0E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 302 381 1.5E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 SMART SM00387 397 509 9.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 399 508 1.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11055 d280aed9f35175de88371760578836cc 509 SUPERFAMILY SSF47384 285 341 9.81E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 SUPERFAMILY SSF51261 209 337 3.66E-45 T 28-03-2018 IPR011055 Duplicated hybrid motif hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 Gene3D G3DSA:3.10.350.10 54 117 2.2E-16 T 28-03-2018 hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 Pfam PF01476 LysM domain 61 103 1.0E-12 T 28-03-2018 IPR018392 LysM domain hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 SMART SM00257 60 104 1.9E-12 T 28-03-2018 IPR018392 LysM domain hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 Pfam PF01551 Peptidase family M23 240 333 1.2E-29 T 28-03-2018 IPR016047 Peptidase M23 hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 Gene3D G3DSA:2.70.70.10 177 340 2.9E-38 T 28-03-2018 hmeg3_RS08830 e98107e807a65ec9a1b577d2d1f28f37 340 SUPERFAMILY SSF54106 59 104 9.81E-11 T 28-03-2018 IPR018392 LysM domain hmeg3_RS22025 832c8ba0311d2f1c194d53d6e00ad8e7 389 Pfam PF00953 Glycosyl transferase family 4 99 307 3.0E-36 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 hmeg3_RS22025 832c8ba0311d2f1c194d53d6e00ad8e7 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 389 1.1E-125 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS22025 832c8ba0311d2f1c194d53d6e00ad8e7 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS22025 832c8ba0311d2f1c194d53d6e00ad8e7 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.867 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS22025 832c8ba0311d2f1c194d53d6e00ad8e7 389 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 4.0E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS22025 832c8ba0311d2f1c194d53d6e00ad8e7 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 hmeg3_RS04880 f3138b76e3fe0c935a4c60f7389489d8 345 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 44 298 6.9E-74 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS04880 f3138b76e3fe0c935a4c60f7389489d8 345 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 8 35 2.2E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal hmeg3_RS04880 f3138b76e3fe0c935a4c60f7389489d8 345 PIRSF PIRSF006470 11 341 3.2E-79 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS04880 f3138b76e3fe0c935a4c60f7389489d8 345 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 44 318 1.3E-78 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS04880 f3138b76e3fe0c935a4c60f7389489d8 345 Gene3D G3DSA:3.40.190.10 163 231 0.042 T 28-03-2018 hmeg3_RS07250 7f6e84410a56ffa7f353eb87fbc4faec 251 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 199 9.8E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS07250 7f6e84410a56ffa7f353eb87fbc4faec 251 Gene3D G3DSA:3.40.225.10 6 251 2.8E-73 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS07250 7f6e84410a56ffa7f353eb87fbc4faec 251 SUPERFAMILY SSF53639 11 223 2.55E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS07250 7f6e84410a56ffa7f353eb87fbc4faec 251 SMART SM01007 19 199 1.0E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS11745 8060cbc5c34455e491b336d99a9477a0 307 PIRSF PIRSF000450 1 306 7.5E-119 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 hmeg3_RS11745 8060cbc5c34455e491b336d99a9477a0 307 SUPERFAMILY SSF52317 18 295 1.05E-92 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS11745 8060cbc5c34455e491b336d99a9477a0 307 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 297 2.2E-95 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 hmeg3_RS11745 8060cbc5c34455e491b336d99a9477a0 307 Gene3D G3DSA:3.40.50.880 34 300 3.1E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS11745 8060cbc5c34455e491b336d99a9477a0 307 Pfam PF04204 Homoserine O-succinyltransferase 2 297 1.0E-113 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 hmeg3_RS11745 8060cbc5c34455e491b336d99a9477a0 307 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-104 T 28-03-2018 hmeg3_RS24555 6c23bb3743a37f7867e1bc94a7f29f89 171 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 5 151 8.3E-28 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN hmeg3_RS24555 6c23bb3743a37f7867e1bc94a7f29f89 171 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 13 158 5.3E-33 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN hmeg3_RS14070 1acc1e3cf7918184543eb10d0563ceb6 216 Gene3D G3DSA:1.10.3720.10 8 212 4.7E-31 T 28-03-2018 hmeg3_RS14070 1acc1e3cf7918184543eb10d0563ceb6 216 SUPERFAMILY SSF161098 11 202 4.45E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14070 1acc1e3cf7918184543eb10d0563ceb6 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 211 1.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS08545 e60f8a28e0562d20d734894a48d88b09 150 Pfam PF01575 MaoC like domain 13 118 3.7E-23 T 28-03-2018 IPR002539 MaoC-like domain hmeg3_RS08545 e60f8a28e0562d20d734894a48d88b09 150 SUPERFAMILY SSF54637 8 147 7.47E-36 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS08545 e60f8a28e0562d20d734894a48d88b09 150 Gene3D G3DSA:3.10.129.10 1 150 4.2E-36 T 28-03-2018 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 Pfam PF03949 Malic enzyme, NAD binding domain 165 359 2.4E-21 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 755 3.9E-92 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 SMART SM00919 163 400 3.6E-136 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 Gene3D G3DSA:3.40.50.10380 5 160 1.1E-33 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 SUPERFAMILY SSF53223 10 161 2.01E-50 T 28-03-2018 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 Gene3D G3DSA:3.40.50.720 161 450 1.0E-82 T 28-03-2018 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 Pfam PF00390 Malic enzyme, N-terminal domain 20 151 2.0E-25 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 SUPERFAMILY SSF53659 429 759 3.17E-84 T 28-03-2018 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 SMART SM01274 18 151 5.0E-75 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 Gene3D G3DSA:3.40.718.10 451 725 2.4E-49 T 28-03-2018 hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 SUPERFAMILY SSF51735 163 439 6.57E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06375 e5e82cd84bd0fa397d534ff73d51fc72 763 PIRSF PIRSF036684 1 763 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 Hamap MF_00415 Flagellar L-ring protein [flgH]. 3 224 22.509 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 PRINTS PR01008 Flagellar L-ring protein signature 140 155 2.5E-19 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 PRINTS PR01008 Flagellar L-ring protein signature 187 201 2.5E-19 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 PRINTS PR01008 Flagellar L-ring protein signature 166 182 2.5E-19 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 PRINTS PR01008 Flagellar L-ring protein signature 203 217 2.5E-19 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 PRINTS PR01008 Flagellar L-ring protein signature 66 78 2.5E-19 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00085 3e285ee90fb1f80f7abe145189002a43 227 Pfam PF02107 Flagellar L-ring protein 45 224 4.3E-48 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS00945 778e541135f90041df7cf16b847fa3ec 421 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 73 397 2.1E-67 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS00945 778e541135f90041df7cf16b847fa3ec 421 Gene3D G3DSA:2.40.50.100 198 398 1.9E-5 T 28-03-2018 hmeg3_RS00945 778e541135f90041df7cf16b847fa3ec 421 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 99 318 3.3E-28 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS00945 778e541135f90041df7cf16b847fa3ec 421 Gene3D G3DSA:1.10.287.470 147 196 3.1E-10 T 28-03-2018 hmeg3_RS00945 778e541135f90041df7cf16b847fa3ec 421 SUPERFAMILY SSF111369 86 323 1.44E-36 T 28-03-2018 hmeg3_RS00945 778e541135f90041df7cf16b847fa3ec 421 Gene3D G3DSA:3.90.1170.30 26 146 1.9E-6 T 28-03-2018 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 Pfam PF13609 Gram-negative porin 9 335 6.7E-45 T 28-03-2018 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 SUPERFAMILY SSF56935 23 364 1.89E-71 T 28-03-2018 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 Gene3D G3DSA:2.40.160.10 11 364 1.2E-59 T 28-03-2018 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 PRINTS PR00184 Neisseria sp. porin signature 307 331 1.7E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 PRINTS PR00184 Neisseria sp. porin signature 58 83 1.7E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 100 110 1.5E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 56 67 1.5E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01260 5a463219d534f20d3e4fb7f1d477ffba 364 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 310 327 1.5E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS16325 1bb0d48734452f53b2c2a181307cc438 438 Gene3D G3DSA:1.20.1250.20 21 232 2.1E-39 T 28-03-2018 hmeg3_RS16325 1bb0d48734452f53b2c2a181307cc438 438 SUPERFAMILY SSF103473 25 436 9.42E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS16325 1bb0d48734452f53b2c2a181307cc438 438 Gene3D G3DSA:1.20.1250.20 247 437 8.6E-21 T 28-03-2018 hmeg3_RS16325 1bb0d48734452f53b2c2a181307cc438 438 Pfam PF07690 Major Facilitator Superfamily 38 400 3.3E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 Gene3D G3DSA:3.40.50.300 290 550 2.9E-57 T 28-03-2018 hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 Gene3D G3DSA:3.40.50.300 12 289 2.5E-54 T 28-03-2018 hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 SMART SM00382 348 524 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 SMART SM00382 31 236 4.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 Pfam PF12848 ABC transporter 230 305 3.7E-13 T 28-03-2018 IPR032781 ABC-transporter extension domain hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 Pfam PF00005 ABC transporter 22 191 7.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 Pfam PF00005 ABC transporter 340 473 2.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 552 1.7E-290 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 SUPERFAMILY SSF52540 12 236 2.04E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00470 a9fc1d84ad54640196a7cf911d54b848 555 SUPERFAMILY SSF52540 302 521 8.89E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18225 9afcce5ba7befbe385948abe2875d198 155 Pfam PF00072 Response regulator receiver domain 22 136 3.8E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18225 9afcce5ba7befbe385948abe2875d198 155 SMART SM00448 20 136 3.1E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18225 9afcce5ba7befbe385948abe2875d198 155 SUPERFAMILY SSF52172 19 141 4.84E-19 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS18225 9afcce5ba7befbe385948abe2875d198 155 Gene3D G3DSA:3.40.50.2300 2 149 1.1E-18 T 28-03-2018 hmeg3_RS22165 3a08a6dc5ce092b9dbcedc3d17f6c3ee 503 SUPERFAMILY SSF56954 68 484 2.09E-110 T 28-03-2018 hmeg3_RS22165 3a08a6dc5ce092b9dbcedc3d17f6c3ee 503 SUPERFAMILY SSF56954 9 34 2.09E-110 T 28-03-2018 hmeg3_RS22165 3a08a6dc5ce092b9dbcedc3d17f6c3ee 503 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 482 9.1E-123 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS22165 3a08a6dc5ce092b9dbcedc3d17f6c3ee 503 Pfam PF02321 Outer membrane efflux protein 296 480 1.4E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS22165 3a08a6dc5ce092b9dbcedc3d17f6c3ee 503 Pfam PF02321 Outer membrane efflux protein 77 269 3.6E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS22165 3a08a6dc5ce092b9dbcedc3d17f6c3ee 503 Gene3D G3DSA:1.20.1600.10 25 486 2.7E-105 T 28-03-2018 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 Pfam PF13609 Gram-negative porin 17 339 9.0E-43 T 28-03-2018 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 103 113 6.9E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 59 70 6.9E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 314 331 6.9E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 SUPERFAMILY SSF56935 26 368 3.66E-73 T 28-03-2018 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 Gene3D G3DSA:2.40.160.10 14 368 1.5E-58 T 28-03-2018 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 PRINTS PR00184 Neisseria sp. porin signature 61 86 4.4E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01140 e0a9182f6bd2a8e848aaebfc9403154e 368 PRINTS PR00184 Neisseria sp. porin signature 311 335 4.4E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 Gene3D G3DSA:2.30.40.10 7 74 2.5E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 SUPERFAMILY SSF51338 497 540 1.18E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 SUPERFAMILY SSF51338 3 66 1.18E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 Gene3D G3DSA:2.30.40.10 490 548 0.016 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 Gene3D G3DSA:3.20.20.140 75 489 5.5E-36 T 28-03-2018 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 Pfam PF07969 Amidohydrolase family 54 538 1.5E-119 T 28-03-2018 IPR013108 Amidohydrolase 3 hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 SUPERFAMILY SSF51556 65 127 8.85E-44 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS05345 7bfaf9402a9ef88aa09a2205b360a523 622 SUPERFAMILY SSF51556 207 498 8.85E-44 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 SUPERFAMILY SSF53850 91 292 6.52E-27 T 28-03-2018 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 Gene3D G3DSA:3.40.190.10 182 266 1.3E-11 T 28-03-2018 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 Gene3D G3DSA:1.10.10.10 1 92 3.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 5.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 Gene3D G3DSA:3.40.190.10 93 181 2.9E-10 T 28-03-2018 hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 SUPERFAMILY SSF46785 1 85 1.41E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24230 3e841e169e6383c9cd08b8af5e106e12 293 Pfam PF03466 LysR substrate binding domain 90 291 1.8E-26 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS11600 3ca3a758d86d4d4ca77994aedd82cdc3 77 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 3 49 4.7E-7 T 28-03-2018 IPR008621 Cbb3-type cytochrome oxidase component hmeg3_RS09120 59edaab82989dddcd6263935480fbab6 279 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 53 153 1.8E-4 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 hmeg3_RS09120 59edaab82989dddcd6263935480fbab6 279 Gene3D G3DSA:3.40.50.1820 12 274 7.3E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09120 59edaab82989dddcd6263935480fbab6 279 SUPERFAMILY SSF53474 29 271 1.96E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06505 ac5e51029fa073d1952f0fc09110512c 309 Pfam PF01734 Patatin-like phospholipase 53 214 2.0E-24 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 hmeg3_RS06505 ac5e51029fa073d1952f0fc09110512c 309 SUPERFAMILY SSF52151 39 304 8.02E-58 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS06505 ac5e51029fa073d1952f0fc09110512c 309 Gene3D G3DSA:3.40.1090.10 40 281 4.7E-47 T 28-03-2018 hmeg3_RS14350 1d3955e343844b7c1f0492e48b8bcb62 354 Gene3D G3DSA:3.30.1780.10 1 138 3.8E-30 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 hmeg3_RS14350 1d3955e343844b7c1f0492e48b8bcb62 354 SUPERFAMILY SSF51735 23 311 1.67E-89 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14350 1d3955e343844b7c1f0492e48b8bcb62 354 Gene3D G3DSA:3.40.50.720 139 295 1.6E-25 T 28-03-2018 hmeg3_RS14350 1d3955e343844b7c1f0492e48b8bcb62 354 PIRSF PIRSF001439 5 321 2.9E-50 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 hmeg3_RS14350 1d3955e343844b7c1f0492e48b8bcb62 354 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 20 311 2.8E-96 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 Pfam PF03466 LysR substrate binding domain 90 293 1.1E-19 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 Gene3D G3DSA:3.40.190.10 186 262 4.3E-6 T 28-03-2018 hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 Gene3D G3DSA:1.10.10.10 1 85 3.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 SUPERFAMILY SSF46785 3 112 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 SUPERFAMILY SSF53850 92 295 6.69E-25 T 28-03-2018 hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 Gene3D G3DSA:3.40.190.10 90 185 1.1E-12 T 28-03-2018 hmeg3_RS18940 b675b9cf53eb980e7ee4d1c26a870cd8 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.6E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 509 7.6E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 SMART SM00388 282 347 5.4E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 SUPERFAMILY SSF55874 336 507 2.36E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Gene3D G3DSA:3.30.565.10 354 512 5.8E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 346 1.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 SMART SM00387 394 511 2.3E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 461 3.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 483 3.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 3.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Pfam PF08521 Two-component sensor kinase N-terminal 51 205 4.8E-42 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 SMART SM00304 229 281 2.1E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 SUPERFAMILY SSF47384 265 346 1.53E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Gene3D G3DSA:1.10.287.130 272 343 1.1E-12 T 28-03-2018 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Gene3D G3DSA:1.20.5.1040 37 90 3.4E-4 T 28-03-2018 hmeg3_RS20210 2ab9a84f44f24ec9cb04b4e391f7e1e3 520 Gene3D G3DSA:1.20.5.1040 184 229 6.8E-9 T 28-03-2018 hmeg3_RS09865 111395c9b28b94437e9dccd7f4b2c59b 402 Pfam PF00155 Aminotransferase class I and II 32 392 6.9E-47 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS09865 111395c9b28b94437e9dccd7f4b2c59b 402 Gene3D G3DSA:3.90.1150.10 291 399 1.2E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS09865 111395c9b28b94437e9dccd7f4b2c59b 402 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 395 5.1E-187 T 28-03-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 hmeg3_RS09865 111395c9b28b94437e9dccd7f4b2c59b 402 SUPERFAMILY SSF53383 2 397 2.58E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS09865 111395c9b28b94437e9dccd7f4b2c59b 402 Gene3D G3DSA:3.40.640.10 66 290 4.9E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS06265 04ad0d911691a39a7776b06e9857fd6d 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 250 1.3E-46 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS06265 04ad0d911691a39a7776b06e9857fd6d 266 SUPERFAMILY SSF53850 7 250 1.41E-50 T 28-03-2018 hmeg3_RS06265 04ad0d911691a39a7776b06e9857fd6d 266 SMART SM00062 36 256 1.2E-35 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS06265 04ad0d911691a39a7776b06e9857fd6d 266 Gene3D G3DSA:3.40.190.10 179 255 0.0068 T 28-03-2018 hmeg3_RS06265 04ad0d911691a39a7776b06e9857fd6d 266 Gene3D G3DSA:3.40.190.10 25 178 3.8E-36 T 28-03-2018 hmeg3_RS20350 e1350315706c44dfb373f3d48b7a1078 123 Gene3D G3DSA:3.40.50.2300 1 122 2.5E-32 T 28-03-2018 hmeg3_RS20350 e1350315706c44dfb373f3d48b7a1078 123 SMART SM00448 4 117 2.4E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20350 e1350315706c44dfb373f3d48b7a1078 123 Pfam PF00072 Response regulator receiver domain 6 117 1.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS20350 e1350315706c44dfb373f3d48b7a1078 123 SUPERFAMILY SSF52172 1 121 2.56E-33 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS07650 0b68da79e2943cec4488dddb794d1749 109 SUPERFAMILY SSF51182 30 101 1.24E-9 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS07650 0b68da79e2943cec4488dddb794d1749 109 Gene3D G3DSA:2.60.120.10 3 109 4.1E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 SUPERFAMILY SSF55021 324 392 2.03E-7 T 28-03-2018 hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 300 1.5E-74 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 Gene3D G3DSA:3.40.50.1100 137 305 1.2E-37 T 28-03-2018 hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 SUPERFAMILY SSF53686 3 309 8.38E-90 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 Pfam PF13291 ACT domain 323 390 1.6E-8 T 28-03-2018 IPR002912 ACT domain hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 Gene3D G3DSA:3.40.50.1100 27 136 8.9E-31 T 28-03-2018 hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 Gene3D G3DSA:3.30.70.260 322 396 7.2E-12 T 28-03-2018 hmeg3_RS24390 082e6f60e1669448b00e8355233fc4ce 399 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 395 7.0E-125 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 hmeg3_RS01710 4a0031c92fe954e41b04a5640b084645 407 Gene3D G3DSA:1.20.1250.20 203 403 4.8E-17 T 28-03-2018 hmeg3_RS01710 4a0031c92fe954e41b04a5640b084645 407 SUPERFAMILY SSF103473 17 397 1.44E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01710 4a0031c92fe954e41b04a5640b084645 407 Gene3D G3DSA:1.20.1250.20 8 188 1.9E-16 T 28-03-2018 hmeg3_RS01710 4a0031c92fe954e41b04a5640b084645 407 Pfam PF07690 Major Facilitator Superfamily 24 292 7.7E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 76 150 1.2E-25 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SUPERFAMILY SSF51126 38 334 3.45E-47 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 Gene3D G3DSA:2.160.20.10 36 332 7.4E-57 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00912 41 153 2.2E-43 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 Pfam PF05860 haemagglutination activity domain 44 153 1.3E-24 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 686 705 3200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 542 578 3100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 610 631 890.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 999 1019 2400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 964 989 1900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 579 600 3300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 511 533 9300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS20680 51d0bdc6887bc6570682b88376ca3870 1307 SMART SM00710 896 918 640.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 SUPERFAMILY SSF52518 341 528 1.43E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 SUPERFAMILY SSF52922 535 663 8.9E-47 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 663 4.4E-302 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 SUPERFAMILY SSF52518 8 322 2.3E-118 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 Gene3D G3DSA:3.40.50.970 1 366 4.6E-123 T 28-03-2018 hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 Pfam PF02779 Transketolase, pyrimidine binding domain 356 526 1.1E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 Gene3D G3DSA:3.40.50.920 543 662 2.3E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 Pfam PF02780 Transketolase, C-terminal domain 542 655 7.1E-20 T 28-03-2018 IPR033248 Transketolase, C-terminal domain hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 SMART SM00861 357 527 2.2E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 Gene3D G3DSA:3.40.50.970 367 542 1.9E-40 T 28-03-2018 hmeg3_RS06785 6f28e1be836b015d9494951b40f3ba62 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 336 1.3E-160 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS23880 c8609783cde2cb17d2446baabb34b18f 301 Gene3D G3DSA:3.40.190.10 180 292 4.3E-14 T 28-03-2018 hmeg3_RS23880 c8609783cde2cb17d2446baabb34b18f 301 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 281 3.1E-47 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23880 c8609783cde2cb17d2446baabb34b18f 301 SUPERFAMILY SSF53850 21 281 9.15E-58 T 28-03-2018 hmeg3_RS23880 c8609783cde2cb17d2446baabb34b18f 301 SMART SM00062 50 282 1.6E-51 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23880 c8609783cde2cb17d2446baabb34b18f 301 Gene3D G3DSA:3.40.190.10 17 179 5.8E-26 T 28-03-2018 hmeg3_RS23880 c8609783cde2cb17d2446baabb34b18f 301 SMART SM00079 52 281 0.0063 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS20015 e39378961864d09843bca281c847d364 193 Gene3D G3DSA:2.40.128.110 27 192 1.4E-37 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS20015 e39378961864d09843bca281c847d364 193 SUPERFAMILY SSF101874 26 191 1.44E-37 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS20015 e39378961864d09843bca281c847d364 193 Pfam PF04264 YceI-like domain 30 190 2.3E-32 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS20015 e39378961864d09843bca281c847d364 193 SMART SM00867 28 192 1.1E-44 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS21850 5aac88f7c545ce349586ea98df7693a9 204 Gene3D G3DSA:1.10.530.10 22 203 4.9E-24 T 28-03-2018 hmeg3_RS21850 5aac88f7c545ce349586ea98df7693a9 204 Pfam PF01464 Transglycosylase SLT domain 95 183 1.0E-13 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 hmeg3_RS21850 5aac88f7c545ce349586ea98df7693a9 204 SUPERFAMILY SSF53955 81 184 2.13E-26 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 Hamap MF_01987 Ribokinase [rbsK]. 1 308 24.829 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 PRINTS PR00990 Ribokinase signature 174 189 1.4E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 PRINTS PR00990 Ribokinase signature 4 25 1.4E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 PRINTS PR00990 Ribokinase signature 225 236 1.4E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 PRINTS PR00990 Ribokinase signature 106 119 1.4E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 PRINTS PR00990 Ribokinase signature 31 50 1.4E-35 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 Pfam PF00294 pfkB family carbohydrate kinase 2 302 2.3E-69 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 Gene3D G3DSA:3.40.1190.20 1 307 5.6E-80 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 2 307 3.7E-106 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 hmeg3_RS07015 56486a9fd67fb674e09bf2e3e2165c40 308 SUPERFAMILY SSF53613 2 305 4.37E-83 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS01090 e0f4d77db74a936504eb348339622d4d 250 SUPERFAMILY SSF52540 11 245 2.77E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01090 e0f4d77db74a936504eb348339622d4d 250 SMART SM00382 38 226 2.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01090 e0f4d77db74a936504eb348339622d4d 250 Pfam PF00005 ABC transporter 30 175 5.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01090 e0f4d77db74a936504eb348339622d4d 250 Gene3D G3DSA:3.40.50.300 10 245 3.0E-52 T 28-03-2018 hmeg3_RS01090 e0f4d77db74a936504eb348339622d4d 250 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS10850 68ee198515e78ea6fe52dd38a72c9100 238 SMART SM00014 109 221 1.6E-16 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS10850 68ee198515e78ea6fe52dd38a72c9100 238 SUPERFAMILY SSF48317 25 234 6.15E-33 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS10850 68ee198515e78ea6fe52dd38a72c9100 238 Gene3D G3DSA:1.20.144.10 13 235 3.2E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS10850 68ee198515e78ea6fe52dd38a72c9100 238 Pfam PF01569 PAP2 superfamily 108 226 2.9E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 SMART SM00382 30 234 4.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 Pfam PF00005 ABC transporter 22 184 1.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 4.0E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 Gene3D G3DSA:3.40.50.300 1 323 1.4E-76 T 28-03-2018 hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 6.5E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS24435 a335b1e086215cd6bf9750f311ac2af1 323 SUPERFAMILY SSF52540 1 256 1.22E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 9.9E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 Gene3D G3DSA:3.40.190.10 182 271 3.2E-22 T 28-03-2018 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 SUPERFAMILY SSF53850 96 297 1.52E-47 T 28-03-2018 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 SUPERFAMILY SSF46785 4 116 2.17E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 Gene3D G3DSA:1.10.10.10 1 88 9.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 Gene3D G3DSA:3.40.190.10 93 181 1.8E-22 T 28-03-2018 hmeg3_RS11005 6a03929d308de212e49f4da279bd9542 303 Pfam PF03466 LysR substrate binding domain 93 295 9.3E-49 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS21820 f65d83709d555c4addd34b1cd1a9ff81 265 Pfam PF00005 ABC transporter 25 164 2.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21820 f65d83709d555c4addd34b1cd1a9ff81 265 SUPERFAMILY SSF52540 6 230 5.73E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21820 f65d83709d555c4addd34b1cd1a9ff81 265 SMART SM00382 34 215 1.7E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21820 f65d83709d555c4addd34b1cd1a9ff81 265 Gene3D G3DSA:3.40.50.300 1 263 2.0E-68 T 28-03-2018 hmeg3_RS21820 f65d83709d555c4addd34b1cd1a9ff81 265 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS23505 8e1a1a4a997cf33891adf1d85c8bbd4b 198 SUPERFAMILY SSF51735 1 182 2.96E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23505 8e1a1a4a997cf33891adf1d85c8bbd4b 198 Gene3D G3DSA:3.40.50.720 1 186 1.6E-33 T 28-03-2018 hmeg3_RS23505 8e1a1a4a997cf33891adf1d85c8bbd4b 198 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 3.2E-20 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal hmeg3_RS21305 a99a78b0eefb43787719e3d0484bd58a 383 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 377 9.6E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS21305 a99a78b0eefb43787719e3d0484bd58a 383 PIRSF PIRSF000390 1 383 1.6E-108 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS21305 a99a78b0eefb43787719e3d0484bd58a 383 SUPERFAMILY SSF53383 2 380 4.22E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS21305 a99a78b0eefb43787719e3d0484bd58a 383 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 1 380 6.6E-169 T 28-03-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase hmeg3_RS21305 a99a78b0eefb43787719e3d0484bd58a 383 Gene3D G3DSA:3.90.1150.10 253 383 1.9E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS21305 a99a78b0eefb43787719e3d0484bd58a 383 Gene3D G3DSA:3.40.640.10 2 252 2.8E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS00455 1cd201c63760ac3fddf48cf054fab2b8 400 Gene3D G3DSA:3.90.1300.10 5 399 1.5E-95 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00455 1cd201c63760ac3fddf48cf054fab2b8 400 Pfam PF01425 Amidase 23 193 1.3E-51 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00455 1cd201c63760ac3fddf48cf054fab2b8 400 Pfam PF01425 Amidase 293 388 1.9E-7 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00455 1cd201c63760ac3fddf48cf054fab2b8 400 SUPERFAMILY SSF75304 11 395 1.31E-88 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS00455 1cd201c63760ac3fddf48cf054fab2b8 400 ProSitePatterns PS00571 Amidases signature. 110 141 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 Gene3D G3DSA:3.30.230.40 2 91 2.8E-36 T 28-03-2018 hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 SUPERFAMILY SSF54211 5 89 6.45E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 64 77 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 Gene3D G3DSA:3.30.230.40 93 198 8.1E-33 T 28-03-2018 hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 5 198 42.959 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 34 177 1.3E-64 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 SUPERFAMILY SSF54211 91 181 4.81E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS03495 4cacd4df68a336727a2071fc40d4349c 198 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 159 171 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 Gene3D G3DSA:1.10.10.10 376 403 0.17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 Pfam PF00155 Aminotransferase class I and II 184 489 2.9E-22 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 88 1.2E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 Gene3D G3DSA:1.10.10.10 33 90 3.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 SUPERFAMILY SSF53383 127 494 1.48E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 Gene3D G3DSA:3.40.640.10 155 375 1.8E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 2.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 2.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 SMART SM00345 29 88 1.7E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 Gene3D G3DSA:3.90.1150.10 404 501 2.1E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS23360 e767a72c40c8b98f36c4f53d384a8110 508 SUPERFAMILY SSF46785 21 92 4.65E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14650 febdca8dcf3a7c43b74f0a31cd62847b 284 Gene3D G3DSA:3.40.50.300 6 217 5.4E-31 T 28-03-2018 hmeg3_RS14650 febdca8dcf3a7c43b74f0a31cd62847b 284 Pfam PF07728 AAA domain (dynein-related subfamily) 33 175 4.0E-15 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 hmeg3_RS14650 febdca8dcf3a7c43b74f0a31cd62847b 284 SUPERFAMILY SSF52540 12 241 3.82E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14650 febdca8dcf3a7c43b74f0a31cd62847b 284 SMART SM00382 29 187 7.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS22090 48c6c43071dd205fc5a300ebba70e7b1 157 Pfam PF07080 Protein of unknown function (DUF1348) 9 138 1.3E-67 T 28-03-2018 IPR009783 Protein of unknown function DUF1348 hmeg3_RS22090 48c6c43071dd205fc5a300ebba70e7b1 157 SUPERFAMILY SSF54427 3 157 2.93E-78 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS22090 48c6c43071dd205fc5a300ebba70e7b1 157 Gene3D G3DSA:3.10.450.50 12 157 2.1E-71 T 28-03-2018 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 Gene3D G3DSA:1.10.3080.10 13 436 8.4E-76 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 PRINTS PR00762 Chloride channel signature 82 99 3.4E-18 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 PRINTS PR00762 Chloride channel signature 386 405 3.4E-18 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 PRINTS PR00762 Chloride channel signature 171 190 3.4E-18 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 PRINTS PR00762 Chloride channel signature 339 359 3.4E-18 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 SUPERFAMILY SSF81340 9 435 2.75E-83 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS15280 621d69fcc89fba63952288806f4b87d3 437 Pfam PF00654 Voltage gated chloride channel 69 418 9.1E-75 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS04400 a5424445918e38137fc074d0d6478256 320 SUPERFAMILY SSF54427 198 319 1.71E-9 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS04400 a5424445918e38137fc074d0d6478256 320 SMART SM00978 188 319 2.2E-37 T 28-03-2018 IPR007379 Tim44-like domain hmeg3_RS04400 a5424445918e38137fc074d0d6478256 320 Pfam PF04280 Tim44-like domain 197 319 2.8E-13 T 28-03-2018 IPR007379 Tim44-like domain hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.1E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 Gene3D G3DSA:3.40.190.10 179 272 1.7E-11 T 28-03-2018 hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 SUPERFAMILY SSF46785 1 83 7.26E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 SUPERFAMILY SSF53850 88 267 5.25E-17 T 28-03-2018 hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 Gene3D G3DSA:1.10.10.10 1 82 4.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 Pfam PF03466 LysR substrate binding domain 88 268 3.3E-18 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS24335 1d1bdf345824120accdf936f23db9ceb 312 Gene3D G3DSA:3.40.190.10 88 178 1.9E-5 T 28-03-2018 hmeg3_RS13920 5e34a5e060c8de62b0d66ae2c479cea7 234 SUPERFAMILY SSF53474 5 215 4.87E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS13920 5e34a5e060c8de62b0d66ae2c479cea7 234 Pfam PF12697 Alpha/beta hydrolase family 29 166 3.6E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS13920 5e34a5e060c8de62b0d66ae2c479cea7 234 Gene3D G3DSA:3.40.50.1820 28 233 2.0E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 45 581 2.0E-203 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 SUPERFAMILY SSF52374 44 371 2.63E-95 T 28-03-2018 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Gene3D G3DSA:1.10.1160.10 287 364 5.3E-32 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 44 347 1.2E-104 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Gene3D G3DSA:2.40.240.10 374 492 5.6E-39 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 PRINTS PR00987 Glutamyl-tRNA synthetase signature 48 60 6.4E-11 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 PRINTS PR00987 Glutamyl-tRNA synthetase signature 231 241 6.4E-11 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 PRINTS PR00987 Glutamyl-tRNA synthetase signature 77 90 6.4E-11 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 PRINTS PR00987 Glutamyl-tRNA synthetase signature 62 73 6.4E-11 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Gene3D G3DSA:3.40.50.620 45 173 1.6E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Gene3D G3DSA:3.40.50.620 179 286 5.8E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 366 560 3.7E-51 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 62 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Gene3D G3DSA:2.40.240.10 493 579 5.5E-31 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 5 581 50.859 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 hmeg3_RS05500 df9899af64f4d52fa7d87f6e88ac6a12 584 SUPERFAMILY SSF50715 366 580 4.5E-65 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 Gene3D G3DSA:1.10.10.60 1 23 1.2E-4 T 28-03-2018 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 Pfam PF13377 Periplasmic binding protein-like domain 180 345 5.7E-23 T 28-03-2018 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 SMART SM00354 11 82 7.7E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 SUPERFAMILY SSF53822 69 336 4.52E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 SUPERFAMILY SSF47413 11 70 6.0E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 Gene3D G3DSA:3.40.50.2300 67 177 1.6E-28 T 28-03-2018 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 Gene3D G3DSA:3.40.50.2300 178 348 1.1E-31 T 28-03-2018 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 Gene3D G3DSA:1.10.260.40 24 66 1.1E-17 T 28-03-2018 hmeg3_RS16100 eb6108f24cd6463f58622b19c4a5d83e 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 59 2.9E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 Gene3D G3DSA:3.40.30.10 2 161 2.7E-51 T 28-03-2018 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 PRINTS PR01011 Glutathione peroxidase family signature 123 132 1.3E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.3E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.3E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 PIRSF PIRSF000303 1 161 9.7E-64 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 SUPERFAMILY SSF52833 3 161 3.2E-62 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 hmeg3_RS04920 a0e35ce21b807e60533bf36a3973fb8d 161 Pfam PF00255 Glutathione peroxidase 4 111 1.9E-42 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 SUPERFAMILY SSF53850 93 299 1.21E-28 T 28-03-2018 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 Gene3D G3DSA:3.40.190.10 181 273 5.4E-16 T 28-03-2018 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 5.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 Gene3D G3DSA:3.40.190.10 94 180 1.5E-11 T 28-03-2018 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 ProDom PD014532 VP3 TRANSFERASE NUCLEOTIDE-BINDING CORE GTP-BINDING INNER GUANYLYLTRANSFERASE NUCLEOTIDYLTRANSFERASE GUANYLYL 107 233 0.002 T 28-03-2018 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 Gene3D G3DSA:1.10.10.10 6 88 3.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 SUPERFAMILY SSF46785 3 85 3.06E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07965 eeee97dffba388db61a4a65ceeefdec4 314 Pfam PF03466 LysR substrate binding domain 93 295 8.1E-26 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS06900 1bcfee97a6fc7fcb4327edcca62dc59e 201 Hamap MF_00045 Oligoribonuclease [orn]. 23 201 43.041 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 hmeg3_RS06900 1bcfee97a6fc7fcb4327edcca62dc59e 201 Gene3D G3DSA:3.30.420.10 23 201 1.5E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS06900 1bcfee97a6fc7fcb4327edcca62dc59e 201 SMART SM00479 27 200 7.3E-21 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS06900 1bcfee97a6fc7fcb4327edcca62dc59e 201 Pfam PF00929 Exonuclease 29 190 1.7E-31 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS06900 1bcfee97a6fc7fcb4327edcca62dc59e 201 SUPERFAMILY SSF53098 23 200 3.04E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS08170 8796471fa89d2bea42b0fb0515f95e2a 266 Pfam PF00691 OmpA family 140 238 6.4E-21 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS08170 8796471fa89d2bea42b0fb0515f95e2a 266 SUPERFAMILY SSF103088 129 244 4.32E-30 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS08170 8796471fa89d2bea42b0fb0515f95e2a 266 Gene3D G3DSA:3.30.1330.60 87 263 1.5E-37 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS08170 8796471fa89d2bea42b0fb0515f95e2a 266 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 56 2.3E-23 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Pfam PF00501 AMP-binding enzyme 120 377 3.0E-31 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 ProSitePatterns PS00455 Putative AMP-binding domain signature. 134 145 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Gene3D G3DSA:2.30.38.10 294 373 6.3E-11 T 28-03-2018 hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Gene3D G3DSA:3.40.50.980 12 114 4.5E-5 T 28-03-2018 hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Gene3D G3DSA:3.40.50.980 115 140 0.002 T 28-03-2018 hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Pfam PF13193 AMP-binding enzyme C-terminal domain 389 462 1.5E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Gene3D G3DSA:3.30.300.30 375 478 2.6E-23 T 28-03-2018 hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 Gene3D G3DSA:3.40.50.980 141 293 6.0E-25 T 28-03-2018 hmeg3_RS16410 49e4ec9484c6d8c220925b0cf1e5f897 485 SUPERFAMILY SSF56801 12 470 8.5E-81 T 28-03-2018 hmeg3_RS21915 614d434f7b4330ad679792265bb8b2a1 296 Pfam PF01478 Type IV leader peptidase family 148 256 1.9E-28 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 hmeg3_RS21915 614d434f7b4330ad679792265bb8b2a1 296 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 33 137 2.9E-29 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal hmeg3_RS21915 614d434f7b4330ad679792265bb8b2a1 296 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 213 223 3.1E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial hmeg3_RS21915 614d434f7b4330ad679792265bb8b2a1 296 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 236 251 3.1E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial hmeg3_RS21915 614d434f7b4330ad679792265bb8b2a1 296 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 224 235 3.1E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial hmeg3_RS21915 614d434f7b4330ad679792265bb8b2a1 296 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 156 173 3.1E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 Pfam PF07729 FCD domain 94 220 7.8E-20 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 SUPERFAMILY SSF46785 17 108 2.46E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 SUPERFAMILY SSF48008 91 227 2.22E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 3.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 3.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 Gene3D G3DSA:1.20.120.530 84 242 8.1E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 1.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 Gene3D G3DSA:1.10.10.10 2 83 6.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 SMART SM00345 25 83 2.0E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13655 14fe0d4a8e06e99df0fa5a00f070292c 256 SMART SM00895 93 221 3.3E-16 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 3.0E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 9.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 9.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 9.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 9.2E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 Gene3D G3DSA:1.20.5.1150 16 52 1.3E-16 T 28-03-2018 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.498 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 Pfam PF01165 Ribosomal protein S21 4 57 5.0E-19 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS19500 9ca7d18f50e513d10f03606d57cd4fcb 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 1.6E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08455 8a466761e93bc1166cc340655c80f4cc 568 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 227 2.9E-21 T 28-03-2018 hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 Gene3D G3DSA:3.30.70.20 107 157 8.4E-6 T 28-03-2018 hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 6.9E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 8.5E-46 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 28.262 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 SUPERFAMILY SSF54862 36 145 5.02E-25 T 28-03-2018 hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 Gene3D G3DSA:3.30.70.20 74 106 2.3E-13 T 28-03-2018 hmeg3_RS13745 00f2d31f439e0b981ca904cfa5a152b1 162 Gene3D G3DSA:3.30.70.20 23 73 5.0E-7 T 28-03-2018 hmeg3_RS14155 c1dd6d87ef4456e597ad33b52e1ecefc 86 Pfam PF09339 IclR helix-turn-helix domain 29 63 5.1E-5 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS14155 c1dd6d87ef4456e597ad33b52e1ecefc 86 SUPERFAMILY SSF46785 12 85 3.91E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14155 c1dd6d87ef4456e597ad33b52e1ecefc 86 Gene3D G3DSA:1.10.10.10 2 86 6.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18015 88ca33737c9b1d7d3193d02916ba9d96 231 Pfam PF13489 Methyltransferase domain 45 198 3.4E-26 T 28-03-2018 hmeg3_RS18015 88ca33737c9b1d7d3193d02916ba9d96 231 SUPERFAMILY SSF53335 10 226 3.22E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS18015 88ca33737c9b1d7d3193d02916ba9d96 231 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 7 224 2.9E-86 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 hmeg3_RS18015 88ca33737c9b1d7d3193d02916ba9d96 231 Gene3D G3DSA:3.40.50.150 2 230 5.2E-50 T 28-03-2018 hmeg3_RS18015 88ca33737c9b1d7d3193d02916ba9d96 231 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 5 230 38.661 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 hmeg3_RS20705 b43dba81d9bf3dd06609536c302f4907 515 Pfam PF10119 Predicted methyltransferase regulatory domain 218 300 3.2E-28 T 28-03-2018 IPR018773 Methyltransferase regulatory domain, predicted hmeg3_RS20705 b43dba81d9bf3dd06609536c302f4907 515 SUPERFAMILY SSF53335 41 154 2.63E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20705 b43dba81d9bf3dd06609536c302f4907 515 SUPERFAMILY SSF53335 223 257 2.63E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20705 b43dba81d9bf3dd06609536c302f4907 515 Gene3D G3DSA:3.40.50.150 4 283 7.3E-13 T 28-03-2018 hmeg3_RS20135 d026be395ed390469af7f433c3069630 174 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 34 9.0E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS20135 d026be395ed390469af7f433c3069630 174 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 33 1.2E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS20135 d026be395ed390469af7f433c3069630 174 Gene3D G3DSA:3.30.700.10 14 174 2.2E-28 T 28-03-2018 hmeg3_RS20135 d026be395ed390469af7f433c3069630 174 Pfam PF00114 Pilin (bacterial filament) 43 173 2.6E-16 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 hmeg3_RS20135 d026be395ed390469af7f433c3069630 174 SUPERFAMILY SSF54523 14 173 5.23E-23 T 28-03-2018 hmeg3_RS20135 d026be395ed390469af7f433c3069630 174 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS08575 92d4b9fe526f38eaaa56c36d4da5cdc9 386 Gene3D G3DSA:3.40.640.10 44 299 2.2E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS08575 92d4b9fe526f38eaaa56c36d4da5cdc9 386 SUPERFAMILY SSF53383 11 385 4.44E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS08575 92d4b9fe526f38eaaa56c36d4da5cdc9 386 Pfam PF00155 Aminotransferase class I and II 32 383 2.8E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS08575 92d4b9fe526f38eaaa56c36d4da5cdc9 386 Gene3D G3DSA:3.90.1150.10 300 386 2.7E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 Gene3D G3DSA:2.40.40.10 246 399 1.9E-35 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 Pfam PF03562 MltA specific insert domain 68 299 1.4E-83 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 SUPERFAMILY SSF50685 57 398 7.67E-134 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 SMART SM00925 142 299 6.3E-94 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 Gene3D G3DSA:2.40.40.10 37 245 6.5E-43 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 Pfam PF06725 3D domain 322 395 2.8E-24 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 hmeg3_RS04470 34a6595fe33cab500d6d4bc4264673d2 399 PIRSF PIRSF019422 2 399 1.7E-131 T 28-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A hmeg3_RS12855 c94f1405e4bfc1dfeb3c6fb7b92d0f3e 282 Pfam PF00756 Putative esterase 23 275 1.4E-54 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 hmeg3_RS12855 c94f1405e4bfc1dfeb3c6fb7b92d0f3e 282 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 4 279 6.5E-138 T 28-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 hmeg3_RS12855 c94f1405e4bfc1dfeb3c6fb7b92d0f3e 282 SUPERFAMILY SSF53474 3 280 2.92E-86 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12855 c94f1405e4bfc1dfeb3c6fb7b92d0f3e 282 Gene3D G3DSA:3.40.50.1820 3 281 5.7E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07235 e41371f0337214e0e4c09053b73ee55d 255 Pfam PF00194 Eukaryotic-type carbonic anhydrase 39 249 7.3E-39 T 28-03-2018 IPR001148 Alpha carbonic anhydrase hmeg3_RS07235 e41371f0337214e0e4c09053b73ee55d 255 SMART SM01057 38 251 1.8E-72 T 28-03-2018 IPR001148 Alpha carbonic anhydrase hmeg3_RS07235 e41371f0337214e0e4c09053b73ee55d 255 SUPERFAMILY SSF51069 36 249 9.81E-59 T 28-03-2018 IPR001148 Alpha carbonic anhydrase hmeg3_RS07235 e41371f0337214e0e4c09053b73ee55d 255 ProSitePatterns PS00162 Alpha-carbonic anhydrases signature. 122 138 - T 28-03-2018 IPR018338 Carbonic anhydrase, alpha-class, conserved site GO:0004089|GO:0006730|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117|Reactome: R-HSA-1475029 hmeg3_RS07235 e41371f0337214e0e4c09053b73ee55d 255 Gene3D G3DSA:3.10.200.10 28 255 1.0E-55 T 28-03-2018 IPR001148 Alpha carbonic anhydrase hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 Pfam PF03466 LysR substrate binding domain 94 303 5.1E-29 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 Gene3D G3DSA:3.40.190.10 94 187 2.1E-16 T 28-03-2018 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 SUPERFAMILY SSF53850 89 302 2.76E-44 T 28-03-2018 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 SUPERFAMILY SSF46785 3 83 7.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 Gene3D G3DSA:3.40.190.10 188 277 5.7E-19 T 28-03-2018 hmeg3_RS24245 a989680700c203b8b9ec53ab9d10061c 316 Gene3D G3DSA:1.10.10.10 2 86 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 Gene3D G3DSA:3.40.50.720 1 38 2.6E-6 T 28-03-2018 hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 Gene3D G3DSA:3.40.50.720 39 251 9.5E-55 T 28-03-2018 hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 248 1.2E-52 T 28-03-2018 hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 SUPERFAMILY SSF51735 3 249 1.44E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 187 1.3E-4 T 28-03-2018 hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 8.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS14435 bbf7b49e27ed351256d6f50c68017d5b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11755 1368252845410766576422154f994d46 469 SUPERFAMILY SSF111369 225 411 7.32E-13 T 28-03-2018 hmeg3_RS11755 1368252845410766576422154f994d46 469 Gene3D G3DSA:2.40.50.100 230 365 4.6E-12 T 28-03-2018 hmeg3_RS11755 1368252845410766576422154f994d46 469 Pfam PF13437 HlyD family secretion protein 333 431 2.8E-11 T 28-03-2018 hmeg3_RS11755 1368252845410766576422154f994d46 469 Pfam PF13533 Biotin-lipoyl like 239 280 2.3E-7 T 28-03-2018 hmeg3_RS13570 75ee653d19803eb9a6ea8d5ee1e45a6f 166 Pfam PF06172 Cupin superfamily (DUF985) 9 145 7.9E-47 T 28-03-2018 IPR009327 Cupin domain of unknown function DUF985 hmeg3_RS13570 75ee653d19803eb9a6ea8d5ee1e45a6f 166 Gene3D G3DSA:2.60.120.10 1 166 4.5E-59 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS13570 75ee653d19803eb9a6ea8d5ee1e45a6f 166 SUPERFAMILY SSF51182 8 165 5.04E-59 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 Gene3D G3DSA:3.30.465.10 99 241 1.6E-37 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 SUPERFAMILY SSF55103 199 472 1.31E-58 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 SUPERFAMILY SSF56176 7 222 5.45E-73 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 Gene3D G3DSA:1.10.45.10 433 472 5.7E-13 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 Pfam PF01565 FAD binding domain 45 182 3.4E-37 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 472 9.4E-52 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 hmeg3_RS17305 1f069559fae82dfccb7013114fe67853 473 Gene3D G3DSA:3.30.43.10 1 98 1.4E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 Pfam PF13286 Phosphohydrolase-associated domain 285 380 1.2E-30 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 32 164 9.6E-57 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 SUPERFAMILY SSF109604 21 383 1.65E-90 T 28-03-2018 hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 SMART SM00471 65 209 1.7E-9 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 Gene3D G3DSA:1.10.3210.10 20 386 2.7E-84 T 28-03-2018 hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 9 382 38.393 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 hmeg3_RS03170 05372f7cfd3c7ea081d56b77a5d976ee 387 Pfam PF01966 HD domain 69 199 8.4E-13 T 28-03-2018 IPR006674 HD domain hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 Gene3D G3DSA:3.30.390.50 227 337 1.4E-21 T 28-03-2018 hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 232 327 1.5E-14 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 222 1.3E-47 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 SMART SM01092 231 329 3.4E-24 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 Gene3D G3DSA:3.30.465.10 60 136 2.6E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 Gene3D G3DSA:3.30.465.10 143 225 1.1E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 SUPERFAMILY SSF55447 229 329 2.75E-24 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 SUPERFAMILY SSF56176 1 222 4.14E-60 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS23550 a5c5468be5983bdaf2de156884ee2dfd 337 Gene3D G3DSA:3.30.43.10 1 56 2.6E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 PIRSF PIRSF001456 3 364 6.8E-133 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 5.2E-135 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 SUPERFAMILY SSF103263 4 353 2.35E-142 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 Gene3D G3DSA:3.60.150.10 3 362 1.2E-151 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 Pfam PF01264 Chorismate synthase 10 345 2.0E-132 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS17270 f94b9185f3e0c3cfb15b6fa7f0502ba5 365 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 35.002 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 Pfam PF01584 CheW-like domain 693 836 8.9E-14 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 Gene3D G3DSA:2.40.50.180 709 781 3.3E-8 T 28-03-2018 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 SMART SM00260 688 835 1.9E-4 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 Gene3D G3DSA:3.30.450.20 104 221 8.6E-6 T 28-03-2018 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 Gene3D G3DSA:3.30.450.20 434 561 1.2E-10 T 28-03-2018 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 Gene3D G3DSA:2.30.30.40 782 826 0.0011 T 28-03-2018 hmeg3_RS02735 1e33d5e3d7c087fa1aca5ee9a41662b1 866 SUPERFAMILY SSF50341 691 836 4.97E-15 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS20345 b30aedad6f4c308222df3d38526a5489 107 Gene3D G3DSA:3.30.750.24 1 106 3.3E-13 T 28-03-2018 IPR002645 STAS domain hmeg3_RS20345 b30aedad6f4c308222df3d38526a5489 107 Pfam PF13466 STAS domain 17 93 4.6E-12 T 28-03-2018 IPR002645 STAS domain hmeg3_RS20345 b30aedad6f4c308222df3d38526a5489 107 SUPERFAMILY SSF52091 1 104 3.53E-17 T 28-03-2018 IPR002645 STAS domain hmeg3_RS12265 fbe6a4ab132045e16e319bbb6f174f18 136 Pfam PF01814 Hemerythrin HHE cation binding domain 3 133 8.8E-10 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 hmeg3_RS12265 fbe6a4ab132045e16e319bbb6f174f18 136 Gene3D G3DSA:1.20.120.520 2 136 3.5E-10 T 28-03-2018 hmeg3_RS14815 72dca60e964304a3ab43f6bb764d7005 143 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 115 6.4E-42 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 hmeg3_RS14815 72dca60e964304a3ab43f6bb764d7005 143 Pfam PF03960 ArsC family 6 114 3.2E-18 T 28-03-2018 IPR006660 Arsenate reductase-like hmeg3_RS14815 72dca60e964304a3ab43f6bb764d7005 143 SUPERFAMILY SSF52833 3 137 7.28E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS14815 72dca60e964304a3ab43f6bb764d7005 143 Gene3D G3DSA:3.40.30.10 1 140 1.4E-43 T 28-03-2018 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Gene3D G3DSA:3.30.43.10 137 249 8.0E-14 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF11880 Domain of unknown function (DUF3400) 1289 1333 7.3E-25 T 28-03-2018 IPR021817 Protein of unknown function DUF3400 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 SUPERFAMILY SSF55103 462 593 7.48E-36 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 SUPERFAMILY SSF55103 741 822 7.48E-36 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF02913 FAD linked oxidases, C-terminal domain 721 821 2.3E-16 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF02913 FAD linked oxidases, C-terminal domain 460 579 3.0E-4 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Gene3D G3DSA:1.10.1060.10 801 962 1.2E-14 T 28-03-2018 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Gene3D G3DSA:3.30.465.10 257 451 6.5E-20 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 SUPERFAMILY SSF46548 836 956 4.97E-14 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF13183 4Fe-4S dicluster domain 861 940 1.9E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF01565 FAD binding domain 197 342 3.3E-23 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 SUPERFAMILY SSF56176 162 429 3.84E-53 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF12447 Protein of unknown function (DUF3683) 22 147 9.3E-52 T 28-03-2018 IPR022153 Protein of unknown function DUF3683 hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 926 937 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF02754 Cysteine-rich domain 1196 1286 4.8E-5 T 28-03-2018 IPR004017 Cysteine-rich domain hmeg3_RS04375 462e53c86b9bb6edf58d752653a3af71 1333 Pfam PF02754 Cysteine-rich domain 1071 1160 3.7E-6 T 28-03-2018 IPR004017 Cysteine-rich domain hmeg3_RS21415 4c11a17bf17a1f917db2922b30f68c21 343 SUPERFAMILY SSF50022 6 128 2.62E-35 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS21415 4c11a17bf17a1f917db2922b30f68c21 343 SUPERFAMILY SSF55961 119 334 6.44E-32 T 28-03-2018 hmeg3_RS21415 4c11a17bf17a1f917db2922b30f68c21 343 Gene3D G3DSA:2.102.10.10 12 110 6.9E-24 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS21415 4c11a17bf17a1f917db2922b30f68c21 343 Gene3D G3DSA:3.90.380.10 111 336 1.1E-42 T 28-03-2018 hmeg3_RS21415 4c11a17bf17a1f917db2922b30f68c21 343 Pfam PF00355 Rieske [2Fe-2S] domain 13 92 1.4E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 1.4E-31 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 Gene3D G3DSA:3.30.1340.10 1 87 3.7E-29 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 SUPERFAMILY SSF55594 1 87 1.44E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.1E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 5.6E-16 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 5.6E-16 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS22985 c2d7eaef3fa862de3b96760dd0e207e3 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 5.6E-16 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like hmeg3_RS00485 7973de4a0ccd729b32010f096923738f 306 Pfam PF01758 Sodium Bile acid symporter family 37 213 8.2E-37 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 hmeg3_RS04805 7f5750866f79aa74cc48a4d75c99079b 88 SUPERFAMILY SSF116842 7 74 3.79E-19 T 28-03-2018 hmeg3_RS04805 7f5750866f79aa74cc48a4d75c99079b 88 Pfam PF02609 Exonuclease VII small subunit 14 64 4.5E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS04805 7f5750866f79aa74cc48a4d75c99079b 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 14.357 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS04805 7f5750866f79aa74cc48a4d75c99079b 88 Gene3D G3DSA:1.10.287.1040 11 74 8.2E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS04805 7f5750866f79aa74cc48a4d75c99079b 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 13 52 1.0E-10 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS04805 7f5750866f79aa74cc48a4d75c99079b 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 13 67 1.4E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 hmeg3_RS06250 d766eddb2902fd27dbc1e8bb466cd694 201 Gene3D G3DSA:3.40.190.10 42 162 1.1E-4 T 28-03-2018 hmeg3_RS06250 d766eddb2902fd27dbc1e8bb466cd694 201 Pfam PF11008 Protein of unknown function (DUF2846) 64 160 6.7E-11 T 28-03-2018 IPR022548 Domain of unknown function DUF2846 hmeg3_RS07855 508c18ca39c6c767e6d819f58ad0fc05 318 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 101 292 1.7E-43 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 hmeg3_RS07855 508c18ca39c6c767e6d819f58ad0fc05 318 SUPERFAMILY SSF160246 16 78 8.37E-11 T 28-03-2018 hmeg3_RS07855 508c18ca39c6c767e6d819f58ad0fc05 318 Gene3D G3DSA:3.40.50.300 116 313 1.6E-30 T 28-03-2018 hmeg3_RS07855 508c18ca39c6c767e6d819f58ad0fc05 318 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 119 298 2.2E-12 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain hmeg3_RS07855 508c18ca39c6c767e6d819f58ad0fc05 318 SUPERFAMILY SSF52540 119 302 7.42E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 233 366 7.7E-19 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 PIRSF PIRSF016578 1 374 3.2E-30 T 28-03-2018 hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 Gene3D G3DSA:2.40.110.10 116 215 2.5E-13 T 28-03-2018 hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 Gene3D G3DSA:1.20.140.10 223 391 3.8E-24 T 28-03-2018 hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 SUPERFAMILY SSF47203 227 380 1.11E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 SUPERFAMILY SSF56645 16 211 2.09E-37 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 Gene3D G3DSA:1.10.540.10 7 115 4.3E-18 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS09190 b26deeab8853ea4a142bfc7117caeb12 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 110 2.3E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS01680 008ad40bffdae02942fab7b9a5b056b5 382 Gene3D G3DSA:3.30.70.270 203 380 1.6E-49 T 28-03-2018 hmeg3_RS01680 008ad40bffdae02942fab7b9a5b056b5 382 SUPERFAMILY SSF55073 224 379 2.75E-39 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS01680 008ad40bffdae02942fab7b9a5b056b5 382 SMART SM00267 208 379 7.8E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01680 008ad40bffdae02942fab7b9a5b056b5 382 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 378 4.7E-36 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01680 008ad40bffdae02942fab7b9a5b056b5 382 Pfam PF00990 Diguanylate cyclase, GGDEF domain 219 375 3.7E-36 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS23740 142ac47a4c40a195dd9a10a08623c34a 189 Gene3D G3DSA:1.10.260.40 39 59 6.2E-6 T 28-03-2018 hmeg3_RS23740 142ac47a4c40a195dd9a10a08623c34a 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 4.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS23740 142ac47a4c40a195dd9a10a08623c34a 189 Gene3D G3DSA:1.10.10.60 1 38 1.4E-13 T 28-03-2018 hmeg3_RS23740 142ac47a4c40a195dd9a10a08623c34a 189 Gene3D G3DSA:1.10.357.10 60 185 8.5E-11 T 28-03-2018 hmeg3_RS23740 142ac47a4c40a195dd9a10a08623c34a 189 SUPERFAMILY SSF46689 3 77 1.18E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS23740 142ac47a4c40a195dd9a10a08623c34a 189 SUPERFAMILY SSF48498 78 184 1.51E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS18845 61bb6bd2d2bfb664d7deccfc895bb566 490 SMART SM00316 37 121 3.5E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS18845 61bb6bd2d2bfb664d7deccfc895bb566 490 SUPERFAMILY SSF50249 39 127 7.23E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS18845 61bb6bd2d2bfb664d7deccfc895bb566 490 Gene3D G3DSA:2.40.50.140 33 126 1.3E-28 T 28-03-2018 hmeg3_RS18845 61bb6bd2d2bfb664d7deccfc895bb566 490 Pfam PF10150 Ribonuclease E/G family 123 394 1.1E-100 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 hmeg3_RS18845 61bb6bd2d2bfb664d7deccfc895bb566 490 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 427 2.8E-154 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 Gene3D G3DSA:3.30.470.20 201 399 2.8E-39 T 28-03-2018 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 Gene3D G3DSA:3.40.50.20 17 116 7.6E-21 T 28-03-2018 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 SUPERFAMILY SSF51246 328 398 7.53E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 Pfam PF02222 ATP-grasp domain 128 303 6.0E-54 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 Pfam PF01370 NAD dependent epimerase/dehydratase family 22 84 1.1E-5 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 SUPERFAMILY SSF52440 7 116 9.64E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 Gene3D G3DSA:3.30.1490.20 133 200 1.5E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 17 398 3.0E-177 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 11 400 52.25 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 hmeg3_RS10180 fbd2cb54557d8bc9abd684a48fa5eae1 403 SUPERFAMILY SSF56059 117 322 1.43E-55 T 28-03-2018 hmeg3_RS14635 661ebc306f575324367d4dc629085eb7 117 Gene3D G3DSA:1.10.760.10 6 109 2.2E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS14635 661ebc306f575324367d4dc629085eb7 117 SUPERFAMILY SSF46626 15 110 3.02E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS14635 661ebc306f575324367d4dc629085eb7 117 Pfam PF00034 Cytochrome c 26 109 5.0E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS14635 661ebc306f575324367d4dc629085eb7 117 PRINTS PR00605 Class IC cytochrome C signature 36 47 2.8E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 hmeg3_RS14635 661ebc306f575324367d4dc629085eb7 117 PRINTS PR00605 Class IC cytochrome C signature 84 106 2.8E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 hmeg3_RS17890 b288d6a27c780ddd15a292a454e0838b 269 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS17890 b288d6a27c780ddd15a292a454e0838b 269 SMART SM00382 36 216 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17890 b288d6a27c780ddd15a292a454e0838b 269 SUPERFAMILY SSF52540 21 232 2.3E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17890 b288d6a27c780ddd15a292a454e0838b 269 Gene3D G3DSA:3.40.50.300 2 240 3.8E-58 T 28-03-2018 hmeg3_RS17890 b288d6a27c780ddd15a292a454e0838b 269 Pfam PF00005 ABC transporter 29 166 1.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 440 4.2E-32 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 129 141 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 PIRSF PIRSF000538 1 488 1.8E-132 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 Gene3D G3DSA:3.30.420.40 241 482 7.6E-54 T 28-03-2018 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 Gene3D G3DSA:3.30.420.40 1 240 8.6E-75 T 28-03-2018 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 SUPERFAMILY SSF53067 246 480 7.77E-55 T 28-03-2018 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 244 1.6E-72 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 SUPERFAMILY SSF53067 2 247 1.3E-73 T 28-03-2018 hmeg3_RS21475 e7d5e230d269d99cbd8f0f1f649bad20 493 TIGRFAM TIGR01312 XylB: xylulokinase 3 479 7.7E-170 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 298 321 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 7.8E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 PRINTS PR00173 Glutamate-aspartate symporter signature 79 104 7.8E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 7.8E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 7.8E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 7.8E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 Pfam PF00375 Sodium:dicarboxylate symporter family 15 404 3.2E-93 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 Gene3D G3DSA:1.10.3860.10 5 411 1.5E-95 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS16350 64c2837fb13857769ee3b6f5dccf7057 443 SUPERFAMILY SSF118215 14 404 9.42E-100 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS21490 c537fafe48c11b00ddd8e191ef37d40a 231 SUPERFAMILY SSF56784 4 222 4.79E-44 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS21490 c537fafe48c11b00ddd8e191ef37d40a 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 188 9.3E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS21490 c537fafe48c11b00ddd8e191ef37d40a 231 Gene3D G3DSA:3.40.50.1000 1 223 2.8E-29 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS21490 c537fafe48c11b00ddd8e191ef37d40a 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 188 2.8E-19 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS18510 b6ef7c4dcfd57781620d957dfe323a08 198 Pfam PF01638 HxlR-like helix-turn-helix 20 105 2.8E-22 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS18510 b6ef7c4dcfd57781620d957dfe323a08 198 SUPERFAMILY SSF46785 5 142 6.72E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18510 b6ef7c4dcfd57781620d957dfe323a08 198 Gene3D G3DSA:1.10.10.10 1 198 1.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18790 5555e1f298a47a60a9e735c5dec1dd86 305 SUPERFAMILY SSF103481 213 303 3.14E-11 T 28-03-2018 hmeg3_RS18790 5555e1f298a47a60a9e735c5dec1dd86 305 SUPERFAMILY SSF103481 54 156 3.14E-12 T 28-03-2018 hmeg3_RS18790 5555e1f298a47a60a9e735c5dec1dd86 305 Pfam PF00892 EamA-like transporter family 19 153 1.8E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS18790 5555e1f298a47a60a9e735c5dec1dd86 305 Pfam PF00892 EamA-like transporter family 166 301 1.4E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS23525 96b348e44ea884ad44d85cc65b6e13c1 275 Gene3D G3DSA:3.40.190.10 26 180 1.1E-39 T 28-03-2018 hmeg3_RS23525 96b348e44ea884ad44d85cc65b6e13c1 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS23525 96b348e44ea884ad44d85cc65b6e13c1 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 257 1.3E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23525 96b348e44ea884ad44d85cc65b6e13c1 275 SMART SM00062 37 259 4.2E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23525 96b348e44ea884ad44d85cc65b6e13c1 275 SUPERFAMILY SSF53850 9 258 4.66E-57 T 28-03-2018 hmeg3_RS23525 96b348e44ea884ad44d85cc65b6e13c1 275 Gene3D G3DSA:3.40.190.10 181 262 7.8E-6 T 28-03-2018 hmeg3_RS22485 21568825c09ea523f653acd18167b1de 178 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 39.821 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 hmeg3_RS22485 21568825c09ea523f653acd18167b1de 178 SUPERFAMILY SSF56235 3 177 5.9E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS22485 21568825c09ea523f653acd18167b1de 178 PIRSF PIRSF039093 1 178 8.2E-83 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 hmeg3_RS22485 21568825c09ea523f653acd18167b1de 178 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 7.1E-81 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 hmeg3_RS22485 21568825c09ea523f653acd18167b1de 178 Gene3D G3DSA:3.60.20.10 7 178 3.2E-28 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS22485 21568825c09ea523f653acd18167b1de 178 Pfam PF00227 Proteasome subunit 5 174 3.1E-20 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 hmeg3_RS21225 1b272cf614e6a3bdeda58992a446c2c6 277 Pfam PF00535 Glycosyl transferase family 2 25 128 5.8E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS21225 1b272cf614e6a3bdeda58992a446c2c6 277 Gene3D G3DSA:3.90.550.10 9 276 5.0E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21225 1b272cf614e6a3bdeda58992a446c2c6 277 SUPERFAMILY SSF53448 22 229 2.38E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 SMART SM00421 166 223 7.2E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 Gene3D G3DSA:1.10.10.10 136 228 1.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 Pfam PF00072 Response regulator receiver domain 11 125 5.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 SUPERFAMILY SSF52172 9 137 2.7E-21 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 Gene3D G3DSA:3.40.50.2300 8 135 1.0E-23 T 28-03-2018 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 SUPERFAMILY SSF46894 164 226 2.55E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 SMART SM00448 9 124 1.9E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 169 219 3.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS15490 ea6c1d9c0777d9b68048ed77c771229e 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 SMART SM00382 44 227 1.4E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 SUPERFAMILY SSF52540 20 258 7.1E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 SUPERFAMILY SSF50331 253 377 3.91E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 19 377 2.0E-149 T 28-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 Gene3D G3DSA:3.40.50.300 17 272 2.3E-77 T 28-03-2018 hmeg3_RS09365 b7217444f807bcda5a095b47245fc78f 379 Pfam PF00005 ABC transporter 35 177 9.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 264 279 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 SMART SM00928 426 471 1.2E-18 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 SUPERFAMILY SSF142984 340 421 6.67E-21 T 28-03-2018 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 SUPERFAMILY SSF140490 422 508 8.5E-29 T 28-03-2018 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 439 450 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 428 509 9.6E-30 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 146 316 3.5E-47 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 SUPERFAMILY SSF52833 3 85 1.3E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS16125 a07eb9a1286771ed45e0121a8e277b3c 516 SUPERFAMILY SSF142019 97 337 6.8E-87 T 28-03-2018 hmeg3_RS17160 c58dfa1c0b2852cfb3843212be22b2ec 281 SMART SM00481 4 69 1.4E-19 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal hmeg3_RS17160 c58dfa1c0b2852cfb3843212be22b2ec 281 Pfam PF02811 PHP domain 5 157 6.6E-9 T 28-03-2018 IPR004013 PHP domain GO:0003824 hmeg3_RS17160 c58dfa1c0b2852cfb3843212be22b2ec 281 Gene3D G3DSA:3.20.20.140 1 262 9.0E-47 T 28-03-2018 hmeg3_RS17160 c58dfa1c0b2852cfb3843212be22b2ec 281 SUPERFAMILY SSF89550 1 82 3.34E-54 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 hmeg3_RS17160 c58dfa1c0b2852cfb3843212be22b2ec 281 SUPERFAMILY SSF89550 165 277 3.34E-54 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 hmeg3_RS22685 a65b0680fd0daa322129d607c5ba0651 531 Gene3D G3DSA:3.40.309.10 280 453 1.9E-18 T 28-03-2018 hmeg3_RS22685 a65b0680fd0daa322129d607c5ba0651 531 Pfam PF00171 Aldehyde dehydrogenase family 37 464 6.2E-43 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22685 a65b0680fd0daa322129d607c5ba0651 531 Gene3D G3DSA:3.40.605.10 4 279 1.8E-47 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS22685 a65b0680fd0daa322129d607c5ba0651 531 SUPERFAMILY SSF53720 24 516 3.4E-92 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 Gene3D G3DSA:3.10.20.30 11 112 3.3E-31 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 28-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 90 1.8E-11 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 SUPERFAMILY SSF54292 4 107 4.26E-31 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 PRINTS PR00355 Adrenodoxin signature 42 52 2.5E-10 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 PRINTS PR00355 Adrenodoxin signature 60 74 2.5E-10 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 PRINTS PR00355 Adrenodoxin signature 83 91 2.5E-10 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 hmeg3_RS15515 9d829a9acd41b2e8a5ad0f2e062ad11e 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 7.6E-56 T 28-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 hmeg3_RS17835 3cd800ac74986b240b79d51b720625f1 242 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 12 217 1.0E-19 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 hmeg3_RS01475 2b2ffd72d0fc41f2bcf253a01db2ed79 255 Pfam PF00005 ABC transporter 32 185 1.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01475 2b2ffd72d0fc41f2bcf253a01db2ed79 255 SUPERFAMILY SSF52540 14 253 1.98E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01475 2b2ffd72d0fc41f2bcf253a01db2ed79 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 254 1.0E-7 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS01475 2b2ffd72d0fc41f2bcf253a01db2ed79 255 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 15 255 9.3E-114 T 28-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD hmeg3_RS01475 2b2ffd72d0fc41f2bcf253a01db2ed79 255 Gene3D G3DSA:3.40.50.300 12 251 9.9E-55 T 28-03-2018 hmeg3_RS19910 0a224f2e2f4c8cabad4e9144b868ce75 761 Pfam PF03968 OstA-like protein 65 190 6.1E-5 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal hmeg3_RS19910 0a224f2e2f4c8cabad4e9144b868ce75 761 Gene3D G3DSA:2.60.450.10 52 205 9.9E-18 T 28-03-2018 hmeg3_RS19910 0a224f2e2f4c8cabad4e9144b868ce75 761 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 17 733 19.618 T 28-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 hmeg3_RS19910 0a224f2e2f4c8cabad4e9144b868ce75 761 Pfam PF04453 Organic solvent tolerance protein 300 673 1.1E-94 T 28-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 Gene3D G3DSA:3.30.1140.32 108 208 5.4E-37 T 28-03-2018 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.7E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 5.4E-92 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 Gene3D G3DSA:3.30.300.20 17 107 1.6E-26 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.441 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 SUPERFAMILY SSF54821 108 206 2.35E-39 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 Pfam PF07650 KH domain 38 110 3.0E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 SMART SM00322 60 125 1.6E-8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 hmeg3_RS22830 6b986292910b3162dee2c97622989a5d 274 SUPERFAMILY SSF54814 2 106 6.28E-37 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 hmeg3_RS01515 823a06e59f8c5b9a36df5028a11f582d 147 Pfam PF01638 HxlR-like helix-turn-helix 41 129 2.9E-23 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS01515 823a06e59f8c5b9a36df5028a11f582d 147 SUPERFAMILY SSF46785 34 144 2.39E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01515 823a06e59f8c5b9a36df5028a11f582d 147 Gene3D G3DSA:1.10.10.10 19 146 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07960 f9ef8027a96d8d86bb592f27d3b5ffc7 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 85 1.8E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain hmeg3_RS07960 f9ef8027a96d8d86bb592f27d3b5ffc7 103 Gene3D G3DSA:3.30.70.100 1 101 1.2E-22 T 28-03-2018 hmeg3_RS07960 f9ef8027a96d8d86bb592f27d3b5ffc7 103 SUPERFAMILY SSF54909 1 98 1.29E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS13735 1e5e07f6b388b94bde35562909f78e15 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 1.9E-22 T 28-03-2018 hmeg3_RS13735 1e5e07f6b388b94bde35562909f78e15 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 102 20.372 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 hmeg3_RS08870 5f2b8a5e3c437d0c99bb7271398f847e 422 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 23 408 1.6E-117 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 hmeg3_RS08870 5f2b8a5e3c437d0c99bb7271398f847e 422 Gene3D G3DSA:3.20.20.70 10 122 0.021 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS08870 5f2b8a5e3c437d0c99bb7271398f847e 422 PIRSF PIRSF004640 10 419 8.3E-129 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 hmeg3_RS08870 5f2b8a5e3c437d0c99bb7271398f847e 422 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 413 28.899 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 hmeg3_RS08870 5f2b8a5e3c437d0c99bb7271398f847e 422 Gene3D G3DSA:3.20.20.70 133 279 2.9E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS08870 5f2b8a5e3c437d0c99bb7271398f847e 422 Pfam PF04551 GcpE protein 29 408 3.6E-112 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 Pfam PF00266 Aminotransferase class-V 20 380 9.1E-88 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 210 229 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 16 408 54.139 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 PIRSF PIRSF005572 17 397 2.4E-137 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 18 417 4.0E-225 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 Gene3D G3DSA:3.40.640.10 28 275 6.8E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 SUPERFAMILY SSF53383 19 403 3.42E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS15545 8e0daf19ad1fadbec5a1d670ddb0b76d 417 Gene3D G3DSA:3.90.1150.10 282 397 1.8E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 414 52.713 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 SUPERFAMILY SSF52540 62 399 8.91E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 SMART SM00994 12 51 7.2E-24 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 394 1.6E-15 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 SMART SM01086 316 411 4.1E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 Gene3D G3DSA:1.10.8.60 316 407 2.2E-31 T 28-03-2018 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 SMART SM00382 112 332 6.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 310 1.7E-49 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 Pfam PF06689 ClpX C4-type zinc finger 13 49 9.5E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 SUPERFAMILY SSF57716 13 48 9.84E-12 T 28-03-2018 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 Gene3D G3DSA:3.40.50.300 57 314 1.1E-70 T 28-03-2018 hmeg3_RS10455 221b9e883f62a112d03ec0afb4bbe99f 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 411 3.2E-202 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 Gene3D G3DSA:3.30.300.70 2 76 2.1E-15 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 Gene3D G3DSA:2.30.30.180 83 152 6.4E-16 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 SUPERFAMILY SSF74942 80 156 4.18E-11 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 Pfam PF17384 RimP C-terminal SH3 domain 82 154 7.7E-13 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 1 155 19.491 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 Pfam PF02576 RimP N-terminal domain 6 79 5.0E-14 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal hmeg3_RS05580 7e37d2e517d616059c97ccff11b733b7 162 SUPERFAMILY SSF75420 2 79 3.27E-11 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 SUPERFAMILY SSF81923 1 143 1.1E-57 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Gene3D G3DSA:3.40.50.300 454 655 9.3E-44 T 28-03-2018 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Gene3D G3DSA:1.10.8.60 656 757 1.3E-19 T 28-03-2018 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Gene3D G3DSA:1.10.1780.10 3 154 2.6E-25 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 736 1.5E-20 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Gene3D G3DSA:3.40.50.300 168 353 1.4E-28 T 28-03-2018 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 494 512 1.5E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 612 1.5E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 565 583 1.5E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 536 554 1.5E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 737 0.0 T 28-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 214 344 3.4E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 SMART SM01086 656 746 5.2E-29 T 28-03-2018 IPR019489 Clp ATPase, C-terminal hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 521 539 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 SMART SM00382 490 666 2.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 SMART SM00382 209 355 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Pfam PF07724 AAA domain (Cdc48 subfamily) 489 650 9.7E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 SUPERFAMILY SSF52540 171 425 2.78E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 305 317 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Gene3D G3DSA:1.10.8.60 354 453 7.2E-28 T 28-03-2018 hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 SUPERFAMILY SSF52540 440 742 1.04E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06640 d853f2eababe8bd3d3ba90175bab5bf7 768 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.7E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 105 6.3E-18 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 SUPERFAMILY SSF56214 1 128 3.53E-26 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 129 2.8E-29 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 129 25.382 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 Gene3D G3DSA:3.90.470.20 1 130 1.2E-32 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 104 3.0E-34 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 hmeg3_RS16655 4b1587e250365eeb91b009c23eb4d7b6 130 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 128 8.0E-23 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 hmeg3_RS21025 62f8a8fb20397b7f14c5b35e079a8194 449 SUPERFAMILY SSF51679 8 439 1.22E-126 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS21025 62f8a8fb20397b7f14c5b35e079a8194 449 PIRSF PIRSF000337 7 447 1.8E-158 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS21025 62f8a8fb20397b7f14c5b35e079a8194 449 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 15 433 9.5E-158 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS21025 62f8a8fb20397b7f14c5b35e079a8194 449 Pfam PF00296 Luciferase-like monooxygenase 22 389 1.6E-72 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS21025 62f8a8fb20397b7f14c5b35e079a8194 449 Gene3D G3DSA:3.20.20.30 2 448 1.1E-101 T 28-03-2018 hmeg3_RS02010 594b11464fed7f33f173a298b9fe6d1d 381 SUPERFAMILY SSF53335 22 368 7.74E-94 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS02010 594b11464fed7f33f173a298b9fe6d1d 381 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 91 310 5.8E-51 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 hmeg3_RS02010 594b11464fed7f33f173a298b9fe6d1d 381 Gene3D G3DSA:3.40.50.150 75 307 6.3E-4 T 28-03-2018 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 3.9E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 3.9E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 3.9E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 Pfam PF01037 Lrp/AsnC ligand binding domain 76 148 1.0E-17 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 5.8E-19 T 28-03-2018 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 SUPERFAMILY SSF46785 8 67 6.83E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 SUPERFAMILY SSF54909 72 157 2.82E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 SMART SM00344 9 118 7.1E-35 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 Gene3D G3DSA:3.30.70.920 62 146 2.4E-15 T 28-03-2018 hmeg3_RS03720 7f1eec3a8b332fca9aaab0f4cf3e6ba0 164 Gene3D G3DSA:1.10.10.10 10 61 1.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05175 5c23e17d51ff8f698d4cc873ffa8acac 191 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 36 4.4E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05175 5c23e17d51ff8f698d4cc873ffa8acac 191 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 36 2.9E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05175 5c23e17d51ff8f698d4cc873ffa8acac 191 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 15 165 4.8E-27 T 28-03-2018 IPR013362 Pilus modification type IV, PilV hmeg3_RS07720 10bc9b7e09a9c756ecf6f4fd3141a70a 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 6 85 8.8E-38 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 hmeg3_RS07720 10bc9b7e09a9c756ecf6f4fd3141a70a 87 SUPERFAMILY SSF143011 4 84 1.83E-26 T 28-03-2018 IPR035095 Toxin RelE-like domain hmeg3_RS07720 10bc9b7e09a9c756ecf6f4fd3141a70a 87 Gene3D G3DSA:3.30.2310.20 2 85 3.2E-25 T 28-03-2018 hmeg3_RS07720 10bc9b7e09a9c756ecf6f4fd3141a70a 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 6 85 6.1E-32 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 hmeg3_RS06100 3eb8c0f5aa5a2d30d1054902b89cc1f3 263 SMART SM00382 34 227 7.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06100 3eb8c0f5aa5a2d30d1054902b89cc1f3 263 Pfam PF00005 ABC transporter 26 165 3.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06100 3eb8c0f5aa5a2d30d1054902b89cc1f3 263 Gene3D G3DSA:3.40.50.300 1 258 3.7E-59 T 28-03-2018 hmeg3_RS06100 3eb8c0f5aa5a2d30d1054902b89cc1f3 263 SUPERFAMILY SSF52540 3 242 1.33E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06100 3eb8c0f5aa5a2d30d1054902b89cc1f3 263 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS21865 0c4fc1dde3700e48a41b7186043ea455 174 Pfam PF08750 CNP1-like family 27 161 5.7E-46 T 28-03-2018 IPR014861 Uncharacterised domain CNP1 hmeg3_RS12680 a5c73c6a0afa9c4e7fa4e5dfff3a4f5d 304 Pfam PF01039 Carboxyl transferase domain 14 196 1.7E-17 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 hmeg3_RS12680 a5c73c6a0afa9c4e7fa4e5dfff3a4f5d 304 Gene3D G3DSA:3.90.226.10 5 296 2.9E-39 T 28-03-2018 hmeg3_RS12680 a5c73c6a0afa9c4e7fa4e5dfff3a4f5d 304 SUPERFAMILY SSF52096 13 207 6.04E-34 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS12680 a5c73c6a0afa9c4e7fa4e5dfff3a4f5d 304 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 8 275 1.4E-112 T 28-03-2018 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 hmeg3_RS17210 b2662a8da945da0dc1ecb2e9d59cc7c8 265 Pfam PF00290 Tryptophan synthase alpha chain 8 259 3.5E-85 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS17210 b2662a8da945da0dc1ecb2e9d59cc7c8 265 SUPERFAMILY SSF51366 1 252 1.13E-89 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS17210 b2662a8da945da0dc1ecb2e9d59cc7c8 265 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS17210 b2662a8da945da0dc1ecb2e9d59cc7c8 265 Gene3D G3DSA:3.20.20.70 2 265 3.1E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS17210 b2662a8da945da0dc1ecb2e9d59cc7c8 265 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 33.568 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS17210 b2662a8da945da0dc1ecb2e9d59cc7c8 265 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 259 2.9E-73 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 2.3E-8 T 28-03-2018 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 2.3E-8 T 28-03-2018 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 2.3E-8 T 28-03-2018 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.3E-8 T 28-03-2018 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 Gene3D G3DSA:1.20.1250.20 3 194 2.2E-30 T 28-03-2018 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 415 8.9E-76 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 Gene3D G3DSA:1.20.1250.20 251 451 5.0E-22 T 28-03-2018 hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 SUPERFAMILY SSF103473 5 190 9.55E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 SUPERFAMILY SSF103473 245 447 9.55E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07100 9a2ed77379dec7048b25bf95b297611c 455 Pfam PF07690 Major Facilitator Superfamily 17 406 2.3E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Pfam PF07676 WD40-like Beta Propeller Repeat 326 360 1.3E-11 T 28-03-2018 IPR011659 WD40-like Beta Propeller hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Pfam PF07676 WD40-like Beta Propeller Repeat 240 273 1.6E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Pfam PF07676 WD40-like Beta Propeller Repeat 199 229 4.2E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Pfam PF07676 WD40-like Beta Propeller Repeat 378 400 7.9E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Pfam PF07676 WD40-like Beta Propeller Repeat 281 316 2.6E-16 T 28-03-2018 IPR011659 WD40-like Beta Propeller hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 26 428 6.9E-156 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Gene3D G3DSA:3.40.50.10070 33 168 7.3E-28 T 28-03-2018 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Hamap MF_00671 Protein TolB [tolB]. 14 427 34.445 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Pfam PF04052 TolB amino-terminal domain 35 133 1.3E-26 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 SUPERFAMILY SSF52964 42 165 6.15E-34 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Gene3D G3DSA:2.130.10.150 169 291 1.2E-16 T 28-03-2018 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 Gene3D G3DSA:2.130.10.150 292 430 1.3E-33 T 28-03-2018 hmeg3_RS18110 15b2385197fe612d04c1c29b93606b39 432 SUPERFAMILY SSF69304 158 429 5.49E-65 T 28-03-2018 hmeg3_RS09405 6bc1a6c057a51dc07793818df832e2f2 375 SUPERFAMILY SSF53474 77 293 4.29E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09405 6bc1a6c057a51dc07793818df832e2f2 375 SUPERFAMILY SSF53474 330 370 4.29E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09405 6bc1a6c057a51dc07793818df832e2f2 375 Gene3D G3DSA:3.40.50.1820 6 374 5.2E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09405 6bc1a6c057a51dc07793818df832e2f2 375 Pfam PF10503 Esterase PHB depolymerase 93 294 1.8E-63 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 hmeg3_RS09405 6bc1a6c057a51dc07793818df832e2f2 375 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 105 288 4.9E-38 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 SMART SM00267 339 515 4.1E-54 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 511 1.5E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 Gene3D G3DSA:3.30.70.270 343 523 2.3E-52 T 28-03-2018 hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 SUPERFAMILY SSF55073 355 516 2.35E-44 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 Gene3D G3DSA:3.30.450.20 181 295 1.2E-12 T 28-03-2018 hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 Gene3D G3DSA:3.30.450.20 47 180 3.4E-17 T 28-03-2018 hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 346 514 5.3E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05890 bb80f134b737f6cec89b980771ba5dd2 525 Pfam PF02743 Cache domain 53 280 9.0E-20 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 Gene3D G3DSA:1.10.10.10 6 81 2.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 SMART SM00345 27 85 4.2E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 Gene3D G3DSA:1.20.120.530 82 228 7.1E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 Pfam PF07729 FCD domain 95 218 1.3E-24 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 SMART SM00895 95 219 2.5E-18 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 SUPERFAMILY SSF48008 92 226 7.06E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 8.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 8.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 85 6.5E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07725 786e7b1209853d7bccb893b1838ac129 244 SUPERFAMILY SSF46785 18 89 1.54E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 Gene3D G3DSA:3.40.50.300 275 550 2.4E-75 T 28-03-2018 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 Gene3D G3DSA:3.40.50.300 7 273 9.7E-66 T 28-03-2018 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 SUPERFAMILY SSF52540 279 526 1.03E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 SUPERFAMILY SSF52540 11 260 1.36E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 SMART SM00382 313 504 6.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 SMART SM00382 37 237 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 271 0.0035 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 506 533 1.5E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 Pfam PF00005 ABC transporter 304 454 3.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03950 8993e95b86dafda3d62facde3e30f711 563 Pfam PF00005 ABC transporter 29 187 3.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16155 64b16aeb238e6a37be8b06e40c6f2a9e 337 PIRSF PIRSF006470 1 331 4.8E-122 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS16155 64b16aeb238e6a37be8b06e40c6f2a9e 337 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 32 288 3.5E-92 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS16155 64b16aeb238e6a37be8b06e40c6f2a9e 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 314 1.8E-98 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 Gene3D G3DSA:3.20.20.360 80 412 3.1E-110 T 28-03-2018 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 ProSitePatterns PS00510 Malate synthase signature. 264 279 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 Gene3D G3DSA:1.20.1220.12 413 528 7.9E-42 T 28-03-2018 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 SUPERFAMILY SSF51645 6 528 4.97E-185 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 Pfam PF01274 Malate synthase 11 528 1.0E-201 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 PIRSF PIRSF001363 1 528 1.2E-247 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 hmeg3_RS08490 dd621cfb36322711c667ce13cf8e8ac6 528 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 528 8.3E-229 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 SUPERFAMILY SSF51735 23 266 4.91E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 1.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 1.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 1.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 Gene3D G3DSA:3.40.50.720 16 59 8.6E-11 T 28-03-2018 hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 Gene3D G3DSA:3.40.50.720 60 268 2.3E-64 T 28-03-2018 hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 9.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 9.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 9.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 9.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 9.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 9.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 24 208 1.9E-4 T 28-03-2018 hmeg3_RS10695 d357ad9afcfbd54abb30556e2a8a361f 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 265 2.0E-65 T 28-03-2018 hmeg3_RS00970 32f6aad85a7916b6aa99a4dae2077cab 206 Gene3D G3DSA:1.10.357.10 66 206 1.1E-14 T 28-03-2018 hmeg3_RS00970 32f6aad85a7916b6aa99a4dae2077cab 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00970 32f6aad85a7916b6aa99a4dae2077cab 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00970 32f6aad85a7916b6aa99a4dae2077cab 206 Gene3D G3DSA:1.10.10.60 1 65 3.0E-21 T 28-03-2018 hmeg3_RS00970 32f6aad85a7916b6aa99a4dae2077cab 206 SUPERFAMILY SSF46689 1 78 7.48E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS00970 32f6aad85a7916b6aa99a4dae2077cab 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 5.0E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS11185 420897ef2cfc0f180f8d73b0737025de 544 SUPERFAMILY SSF48557 3 533 1.65E-158 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS11185 420897ef2cfc0f180f8d73b0737025de 544 Pfam PF00221 Aromatic amino acid lyase 11 504 6.9E-160 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 hmeg3_RS11185 420897ef2cfc0f180f8d73b0737025de 544 Gene3D G3DSA:1.20.200.10 209 542 2.0E-105 T 28-03-2018 hmeg3_RS11185 420897ef2cfc0f180f8d73b0737025de 544 Gene3D G3DSA:1.10.275.10 2 207 4.4E-59 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS11185 420897ef2cfc0f180f8d73b0737025de 544 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 hmeg3_RS15425 a17e6520e6ed624806c0122756a7b50c 397 Gene3D G3DSA:3.10.310.10 194 375 1.2E-71 T 28-03-2018 hmeg3_RS15425 a17e6520e6ed624806c0122756a7b50c 397 SUPERFAMILY SSF54506 2 182 1.33E-71 T 28-03-2018 hmeg3_RS15425 a17e6520e6ed624806c0122756a7b50c 397 Pfam PF04303 PrpF protein 6 393 7.6E-179 T 28-03-2018 IPR007400 PrpF protein hmeg3_RS15425 a17e6520e6ed624806c0122756a7b50c 397 SUPERFAMILY SSF54506 191 395 2.51E-77 T 28-03-2018 hmeg3_RS15425 a17e6520e6ed624806c0122756a7b50c 397 Gene3D G3DSA:3.10.310.10 3 193 2.6E-84 T 28-03-2018 hmeg3_RS15425 a17e6520e6ed624806c0122756a7b50c 397 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 4 397 7.2E-233 T 28-03-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 hmeg3_RS17845 b1853b21eb46156510639c54dbbab9e0 207 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 hmeg3_RS17845 b1853b21eb46156510639c54dbbab9e0 207 Gene3D G3DSA:3.20.20.70 1 206 3.6E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS17845 b1853b21eb46156510639c54dbbab9e0 207 SUPERFAMILY SSF51569 2 204 9.34E-65 T 28-03-2018 hmeg3_RS17845 b1853b21eb46156510639c54dbbab9e0 207 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 35 44 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 hmeg3_RS17845 b1853b21eb46156510639c54dbbab9e0 207 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 4 203 3.0E-76 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 hmeg3_RS17845 b1853b21eb46156510639c54dbbab9e0 207 Pfam PF01081 KDPG and KHG aldolase 4 198 4.1E-71 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 hmeg3_RS23050 dae417e756b41cea2fb59331dc51c0dd 114 Pfam PF08895 Domain of unknown function (DUF1840) 1 112 7.5E-29 T 28-03-2018 IPR014991 Protein of unknown function DUF1840 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 SUPERFAMILY SSF46785 1 86 9.67E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 SUPERFAMILY SSF53850 88 298 1.09E-41 T 28-03-2018 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.9E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 Gene3D G3DSA:1.10.10.10 1 89 8.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 Pfam PF03466 LysR substrate binding domain 87 296 8.7E-48 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 Gene3D G3DSA:3.40.190.10 177 274 1.9E-28 T 28-03-2018 hmeg3_RS05010 35fbdcb8687a756b63cb0d4a241fb150 315 Gene3D G3DSA:3.40.190.10 90 176 3.1E-22 T 28-03-2018 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 Pfam PF00384 Molybdopterin oxidoreductase 113 495 7.2E-20 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 Gene3D G3DSA:3.40.50.740 114 338 3.6E-35 T 28-03-2018 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 Gene3D G3DSA:3.40.50.740 339 610 1.3E-40 T 28-03-2018 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 PIRSF PIRSF000144 1 774 0.0 T 28-03-2018 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 SUPERFAMILY SSF53706 51 637 7.33E-139 T 28-03-2018 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 SUPERFAMILY SSF50692 656 772 8.82E-17 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 16 769 1.4E-288 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 Pfam PF01568 Molydopterin dinucleotide binding domain 657 762 1.4E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 hmeg3_RS14160 a0d6292db57701cf825efcad0b3d970b 778 Gene3D G3DSA:2.40.40.20 644 778 5.0E-22 T 28-03-2018 hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 SMART SM01011 1 138 4.2E-62 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 Gene3D G3DSA:3.90.230.10 174 448 4.9E-87 T 28-03-2018 hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 Gene3D G3DSA:3.40.350.10 1 173 5.6E-45 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 354 366 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 124 2.6E-33 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 SUPERFAMILY SSF53092 2 176 6.8E-50 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 Pfam PF00557 Metallopeptidase family M24 183 424 1.5E-63 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS19925 101cc472391e9e966e44ce2335b7534c 448 SUPERFAMILY SSF55920 178 446 1.18E-84 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS05730 e493eda221a5b19aa0d6ded3d0b9f8ee 457 Pfam PF03972 MmgE/PrpD family 8 424 7.4E-104 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 hmeg3_RS05730 e493eda221a5b19aa0d6ded3d0b9f8ee 457 Gene3D G3DSA:1.10.4100.10 1 310 1.2E-85 T 28-03-2018 hmeg3_RS05730 e493eda221a5b19aa0d6ded3d0b9f8ee 457 SUPERFAMILY SSF103378 4 425 2.09E-97 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 hmeg3_RS08665 9158238a7ebea48b49773584e95d5152 390 Gene3D G3DSA:3.40.640.10 5 258 2.1E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS08665 9158238a7ebea48b49773584e95d5152 390 Gene3D G3DSA:3.90.1150.10 259 389 2.6E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS08665 9158238a7ebea48b49773584e95d5152 390 PIRSF PIRSF001434 2 389 2.3E-114 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS08665 9158238a7ebea48b49773584e95d5152 390 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 9 386 7.4E-123 T 28-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 hmeg3_RS08665 9158238a7ebea48b49773584e95d5152 390 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 386 2.0E-91 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS08665 9158238a7ebea48b49773584e95d5152 390 SUPERFAMILY SSF53383 23 387 1.99E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 9.1E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 Pfam PF03466 LysR substrate binding domain 88 289 8.4E-28 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 SUPERFAMILY SSF46785 1 110 2.36E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 Gene3D G3DSA:3.40.190.10 89 179 3.2E-14 T 28-03-2018 hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 SUPERFAMILY SSF53850 89 295 1.66E-28 T 28-03-2018 hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 Gene3D G3DSA:1.10.10.10 1 88 8.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16320 a7238757cf8414c8bc7deaebe814be31 309 Gene3D G3DSA:3.40.190.10 180 263 4.1E-10 T 28-03-2018 hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 SUPERFAMILY SSF53850 105 296 7.24E-26 T 28-03-2018 hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 SUPERFAMILY SSF46785 8 94 7.87E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 Gene3D G3DSA:3.40.190.10 187 269 0.0085 T 28-03-2018 hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 Pfam PF03466 LysR substrate binding domain 98 295 1.8E-23 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 1.8E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 Gene3D G3DSA:3.40.190.10 95 186 1.3E-15 T 28-03-2018 hmeg3_RS23445 44e4fc5c97fee5df2da02d9d5eed7305 298 Gene3D G3DSA:1.10.10.10 4 89 9.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 SMART SM00304 216 268 8.0E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 114 5.4E-13 T 28-03-2018 IPR000014 PAS domain hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 SMART SM00283 269 516 8.7E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 328 482 5.4E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 SMART SM00086 80 121 2.5E-4 T 28-03-2018 IPR001610 PAC motif hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 Pfam PF08447 PAS fold 31 114 6.8E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 SUPERFAMILY SSF55785 21 114 3.49E-25 T 28-03-2018 IPR000014 PAS domain hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 SUPERFAMILY SSF58104 236 517 5.36E-72 T 28-03-2018 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 Gene3D G3DSA:3.40.50.10600 12 129 9.3E-26 T 28-03-2018 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 Gene3D G3DSA:1.10.287.950 324 520 5.2E-46 T 28-03-2018 hmeg3_RS21470 d75ddbebfef8de477ab266365a615448 520 Gene3D G3DSA:1.10.287.950 222 323 2.5E-17 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Gene3D G3DSA:3.30.460.10 641 797 2.3E-51 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Gene3D G3DSA:3.30.460.10 102 278 7.7E-56 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Gene3D G3DSA:1.10.4050.10 4 100 0.014 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Gene3D G3DSA:1.10.4050.10 530 640 4.4E-22 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 SUPERFAMILY SSF81593 801 930 2.51E-28 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Pfam PF08335 GlnD PII-uridylyltransferase 291 435 9.4E-44 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Pfam PF08335 GlnD PII-uridylyltransferase 816 906 1.4E-7 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 SUPERFAMILY SSF81301 529 800 2.83E-75 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 SUPERFAMILY SSF81301 15 280 1.25E-66 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Gene3D G3DSA:1.20.120.330 798 931 2.1E-32 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 10 931 18.462 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 61 267 1.2E-57 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 557 791 1.0E-64 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 SUPERFAMILY SSF81593 281 435 8.63E-43 T 28-03-2018 hmeg3_RS06810 9d381e7475a059664d5bb5e2cd814f80 931 Gene3D G3DSA:1.20.120.330 279 439 5.6E-48 T 28-03-2018 hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 Pfam PF13899 Thioredoxin-like 512 587 2.9E-10 T 28-03-2018 hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 SUPERFAMILY SSF52833 500 613 3.33E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 Gene3D G3DSA:3.40.30.10 492 616 1.9E-17 T 28-03-2018 hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 SUPERFAMILY SSF74863 56 169 8.11E-32 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 Gene3D G3DSA:2.60.40.1250 53 178 2.1E-33 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 Pfam PF11412 Disulphide bond corrector protein DsbC 58 168 6.8E-29 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 217 418 2.6E-19 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 33 616 34.042 T 28-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 hmeg3_RS22705 a41d0391c58e7837b73c6675766cc817 616 ProSitePatterns PS00194 Thioredoxin family active site. 524 542 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 hmeg3_RS10825 9fcc3790e5e740870331d37af4d37437 293 Gene3D G3DSA:3.40.50.1820 27 292 2.3E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS10825 9fcc3790e5e740870331d37af4d37437 293 SUPERFAMILY SSF53474 37 289 3.71E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS10825 9fcc3790e5e740870331d37af4d37437 293 Pfam PF07859 alpha/beta hydrolase fold 72 165 3.8E-16 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS00030 397ec8c9d1d989371afd27af0563fd11 393 Gene3D G3DSA:3.30.360.10 137 304 5.3E-30 T 28-03-2018 hmeg3_RS00030 397ec8c9d1d989371afd27af0563fd11 393 SUPERFAMILY SSF55347 123 377 1.44E-59 T 28-03-2018 hmeg3_RS00030 397ec8c9d1d989371afd27af0563fd11 393 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 122 346 3.0E-15 T 28-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 hmeg3_RS00030 397ec8c9d1d989371afd27af0563fd11 393 SUPERFAMILY SSF51735 1 172 1.42E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00030 397ec8c9d1d989371afd27af0563fd11 393 Gene3D G3DSA:3.40.50.720 1 136 5.5E-17 T 28-03-2018 hmeg3_RS00030 397ec8c9d1d989371afd27af0563fd11 393 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 98 8.6E-13 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 hmeg3_RS00695 d8cd9189a51ac83184b86dc6a13ad1f0 289 Pfam PF08667 BetR domain 17 145 6.2E-7 T 28-03-2018 IPR013975 Transcription regulator BetR, N-terminal hmeg3_RS00695 d8cd9189a51ac83184b86dc6a13ad1f0 289 Gene3D G3DSA:3.40.50.2300 156 284 1.7E-6 T 28-03-2018 hmeg3_RS00695 d8cd9189a51ac83184b86dc6a13ad1f0 289 SUPERFAMILY SSF52172 152 282 1.85E-5 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05745 705cb9fd919b87acc1d102c18c4bc998 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 7.2E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05745 705cb9fd919b87acc1d102c18c4bc998 291 SUPERFAMILY SSF53850 97 288 5.43E-22 T 28-03-2018 hmeg3_RS05745 705cb9fd919b87acc1d102c18c4bc998 291 Pfam PF03466 LysR substrate binding domain 96 286 2.3E-19 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS05745 705cb9fd919b87acc1d102c18c4bc998 291 SUPERFAMILY SSF46785 10 93 1.26E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05745 705cb9fd919b87acc1d102c18c4bc998 291 Gene3D G3DSA:3.40.190.10 87 263 1.3E-15 T 28-03-2018 hmeg3_RS05745 705cb9fd919b87acc1d102c18c4bc998 291 Gene3D G3DSA:1.10.10.10 6 86 6.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16605 c289ad9af6847630b949836b9bce860a 184 SUPERFAMILY SSF53254 2 166 9.42E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS16605 c289ad9af6847630b949836b9bce860a 184 SMART SM00855 2 151 2.2E-8 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS16605 c289ad9af6847630b949836b9bce860a 184 PIRSF PIRSF000709 47 174 0.008 T 28-03-2018 hmeg3_RS16605 c289ad9af6847630b949836b9bce860a 184 Gene3D G3DSA:3.40.50.1240 1 183 4.1E-27 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS16605 c289ad9af6847630b949836b9bce860a 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 171 2.3E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 6 103 5.1E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 SMART SM01403 9 103 1.1E-56 T 28-03-2018 IPR027486 Ribosomal protein S10 domain hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 PRINTS PR00971 Ribosomal protein S10 family signature 7 20 3.8E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 PRINTS PR00971 Ribosomal protein S10 family signature 42 57 3.8E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 PRINTS PR00971 Ribosomal protein S10 family signature 63 77 3.8E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 ProSitePatterns PS00361 Ribosomal protein S10 signature. 31 46 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 Gene3D G3DSA:3.30.70.600 5 105 1.2E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 5 104 27.64 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 Pfam PF00338 Ribosomal protein S10p/S20e 9 103 7.4E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain hmeg3_RS22865 0a27282a168d5fda3417a9deebb70fbe 105 SUPERFAMILY SSF54999 7 104 3.14E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain hmeg3_RS21965 6d1a99566c644adde933427953a27c04 324 SUPERFAMILY SSF51261 176 305 6.28E-54 T 28-03-2018 IPR011055 Duplicated hybrid motif hmeg3_RS21965 6d1a99566c644adde933427953a27c04 324 Pfam PF01551 Peptidase family M23 207 301 6.5E-32 T 28-03-2018 IPR016047 Peptidase M23 hmeg3_RS21965 6d1a99566c644adde933427953a27c04 324 Gene3D G3DSA:2.70.70.10 64 307 4.8E-42 T 28-03-2018 hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 Gene3D G3DSA:3.30.450.40 84 263 1.3E-48 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 SUPERFAMILY SSF46785 20 88 3.14E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 Pfam PF09339 IclR helix-turn-helix domain 22 70 1.6E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 Pfam PF01614 Bacterial transcriptional regulator 134 259 3.0E-32 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 SUPERFAMILY SSF55781 75 261 4.05E-49 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 SMART SM00346 17 107 4.1E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS20550 5e29af97be76f0e80d23d4d619607970 265 Gene3D G3DSA:1.10.10.10 17 79 3.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24290 96784ca7d6023fd65a64de92ff23949f 238 Gene3D G3DSA:3.40.1800.10 146 223 1.3E-9 T 28-03-2018 hmeg3_RS24290 96784ca7d6023fd65a64de92ff23949f 238 Pfam PF01844 HNH endonuclease 167 217 6.6E-10 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 hmeg3_RS24290 96784ca7d6023fd65a64de92ff23949f 238 SMART SM00507 154 213 2.6E-4 T 28-03-2018 IPR003615 HNH nuclease hmeg3_RS17780 1f5c0a236d33b49c2ed29e627e547789 91 Gene3D G3DSA:1.10.3880.10 2 89 6.7E-41 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 hmeg3_RS17780 1f5c0a236d33b49c2ed29e627e547789 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 8.7E-43 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 hmeg3_RS17780 1f5c0a236d33b49c2ed29e627e547789 91 PIRSF PIRSF029827 1 90 2.7E-40 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 hmeg3_RS17780 1f5c0a236d33b49c2ed29e627e547789 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.622 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 hmeg3_RS17780 1f5c0a236d33b49c2ed29e627e547789 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 6.0E-33 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 hmeg3_RS17780 1f5c0a236d33b49c2ed29e627e547789 91 SUPERFAMILY SSF111148 1 89 7.32E-39 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 330 344 1.9E-10 T 28-03-2018 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 302 318 1.9E-10 T 28-03-2018 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 444 456 1.9E-10 T 28-03-2018 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 480 504 1.9E-10 T 28-03-2018 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 Gene3D G3DSA:3.40.50.150 300 669 5.6E-29 T 28-03-2018 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 Pfam PF02384 N-6 DNA Methylase 286 532 1.5E-12 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 447 453 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS02100 2530151842807fb566bacc09e5930db3 1020 SUPERFAMILY SSF53335 155 557 5.74E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS05530 e925b6435af9c336d7578ae4f3db0017 253 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 10 248 5.2E-42 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 hmeg3_RS05530 e925b6435af9c336d7578ae4f3db0017 253 SUPERFAMILY SSF51695 3 249 5.76E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 hmeg3_RS05530 e925b6435af9c336d7578ae4f3db0017 253 Gene3D G3DSA:3.20.20.190 2 253 4.9E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 hmeg3_RS21805 aef527e7144270543d862845d43a293f 210 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 67 179 1.9E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 hmeg3_RS21805 aef527e7144270543d862845d43a293f 210 SUPERFAMILY SSF55846 18 191 5.63E-63 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 hmeg3_RS21805 aef527e7144270543d862845d43a293f 210 SMART SM00644 30 178 4.6E-49 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 hmeg3_RS21805 aef527e7144270543d862845d43a293f 210 Gene3D G3DSA:3.40.80.10 15 198 2.0E-50 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 hmeg3_RS01335 6fd2e7b6b9ef7fea3129f46d003f09f7 270 SMART SM00382 36 230 6.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01335 6fd2e7b6b9ef7fea3129f46d003f09f7 270 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 252 1.1E-5 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS01335 6fd2e7b6b9ef7fea3129f46d003f09f7 270 SUPERFAMILY SSF52540 12 251 7.46E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01335 6fd2e7b6b9ef7fea3129f46d003f09f7 270 Pfam PF00005 ABC transporter 28 183 1.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01335 6fd2e7b6b9ef7fea3129f46d003f09f7 270 Gene3D G3DSA:3.40.50.300 1 270 9.8E-54 T 28-03-2018 hmeg3_RS19255 76fec9c1669b5e98e3c9d279ee1146c7 250 Hamap MF_00943 Maleate isomerase [maiA]. 5 250 50.67 T 28-03-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 hmeg3_RS19255 76fec9c1669b5e98e3c9d279ee1146c7 250 PIRSF PIRSF015736 1 250 4.4E-70 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase hmeg3_RS19255 76fec9c1669b5e98e3c9d279ee1146c7 250 Gene3D G3DSA:3.40.50.2300 127 230 2.6E-4 T 28-03-2018 hmeg3_RS18915 e85f58f02606bdfe642e4c2ead39eabd 331 Pfam PF01501 Glycosyl transferase family 8 16 264 3.0E-45 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 hmeg3_RS18915 e85f58f02606bdfe642e4c2ead39eabd 331 Gene3D G3DSA:3.90.550.10 15 290 6.1E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS18915 e85f58f02606bdfe642e4c2ead39eabd 331 Pfam PF08437 Glycosyl transferase family 8 C-terminal 271 319 1.8E-9 T 28-03-2018 IPR013645 Glycosyl transferase, family 8, C-terminal GO:0008918|GO:0009103 hmeg3_RS18915 e85f58f02606bdfe642e4c2ead39eabd 331 SUPERFAMILY SSF53448 16 284 3.37E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS19875 8a148a5860136d4a9e349146044180eb 135 Gene3D G3DSA:3.10.180.10 1 133 1.5E-36 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS19875 8a148a5860136d4a9e349146044180eb 135 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 hmeg3_RS19875 8a148a5860136d4a9e349146044180eb 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 7.4E-24 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS19875 8a148a5860136d4a9e349146044180eb 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 130 9.7E-66 T 28-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 hmeg3_RS19875 8a148a5860136d4a9e349146044180eb 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 hmeg3_RS19875 8a148a5860136d4a9e349146044180eb 135 SUPERFAMILY SSF54593 1 128 2.28E-35 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS03025 4db2d87159806d22cce18a68baa8e8f5 278 Gene3D G3DSA:2.40.230.20 21 271 1.0E-61 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 hmeg3_RS03025 4db2d87159806d22cce18a68baa8e8f5 278 SUPERFAMILY SSF111364 29 278 1.83E-35 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 hmeg3_RS08540 0539b37e44abb951c1a7afc58ba0d09b 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS08540 0539b37e44abb951c1a7afc58ba0d09b 216 SMART SM00882 6 206 1.0E-79 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS08540 0539b37e44abb951c1a7afc58ba0d09b 216 Pfam PF01144 Coenzyme A transferase 7 204 2.0E-37 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS08540 0539b37e44abb951c1a7afc58ba0d09b 216 Gene3D G3DSA:3.40.1080.10 3 216 6.3E-70 T 28-03-2018 hmeg3_RS08540 0539b37e44abb951c1a7afc58ba0d09b 216 SUPERFAMILY SSF100950 3 214 8.37E-72 T 28-03-2018 hmeg3_RS08540 0539b37e44abb951c1a7afc58ba0d09b 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 5.9E-96 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 Gene3D G3DSA:1.10.10.10 7 37 0.0031 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 SUPERFAMILY SSF47413 22 80 1.03E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 SUPERFAMILY SSF53822 82 349 9.74E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 Gene3D G3DSA:3.40.50.2300 195 337 8.1E-41 T 28-03-2018 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 24 69 1.0E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 Gene3D G3DSA:3.40.50.2300 75 194 4.0E-27 T 28-03-2018 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 Pfam PF13377 Periplasmic binding protein-like domain 189 349 1.1E-32 T 28-03-2018 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 25 43 - T 28-03-2018 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 Gene3D G3DSA:1.10.260.40 38 74 5.4E-19 T 28-03-2018 hmeg3_RS05095 901d11542076e687426f5e787bf6c52c 349 SMART SM00354 22 92 2.2E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 SUPERFAMILY SSF52507 5 184 1.57E-56 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 Gene3D G3DSA:3.40.50.10300 184 401 2.3E-62 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 Pfam PF02441 Flavoprotein 6 180 3.1E-42 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 SUPERFAMILY SSF102645 185 396 1.11E-70 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 392 2.0E-124 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 368 1.4E-63 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 hmeg3_RS06655 81d7e73d82cffa89a36a8e493b3e6432 402 Gene3D G3DSA:3.40.50.1950 1 183 1.2E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 hmeg3_RS13265 916a71f785db16a87af85a10c170087b 301 Pfam PF03755 YicC-like family, N-terminal region 1 150 4.2E-40 T 28-03-2018 IPR013527 YicC-like, N-terminal hmeg3_RS13265 916a71f785db16a87af85a10c170087b 301 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 301 2.6E-69 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 hmeg3_RS13265 916a71f785db16a87af85a10c170087b 301 Pfam PF08340 Domain of unknown function (DUF1732) 217 301 3.3E-32 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 Pfam PF01047 MarR family 49 106 1.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 Gene3D G3DSA:1.10.287.100 123 159 5.0E-5 T 28-03-2018 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 SMART SM00347 40 142 5.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 SUPERFAMILY SSF46785 17 156 2.98E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01205 e5aace2172e5e8f2205ea0244a29d756 175 Gene3D G3DSA:1.10.10.10 38 122 8.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 Gene3D G3DSA:1.10.287.950 155 320 8.0E-19 T 28-03-2018 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 Gene3D G3DSA:1.10.287.950 321 517 1.1E-45 T 28-03-2018 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 SMART SM00283 266 513 1.4E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 1.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 1.8E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS13510 256860fde28584718f6e32d5f81e6312 540 SUPERFAMILY SSF58104 241 514 2.35E-70 T 28-03-2018 hmeg3_RS11310 678fc7955226e0d237bf56c92caa8774 75 SUPERFAMILY SSF89807 10 74 1.57E-24 T 28-03-2018 IPR009923 Dodecin hmeg3_RS11310 678fc7955226e0d237bf56c92caa8774 75 Pfam PF07311 Dodecin 12 74 2.5E-28 T 28-03-2018 IPR009923 Dodecin hmeg3_RS11310 678fc7955226e0d237bf56c92caa8774 75 Gene3D G3DSA:3.30.1660.10 10 74 3.9E-29 T 28-03-2018 IPR025543 Dodecin-like hmeg3_RS09325 b21e2bc5d9159304f39d92b11afa5784 524 Gene3D G3DSA:1.10.287.950 31 320 1.4E-13 T 28-03-2018 hmeg3_RS09325 b21e2bc5d9159304f39d92b11afa5784 524 Gene3D G3DSA:1.10.287.950 321 517 4.1E-46 T 28-03-2018 hmeg3_RS09325 b21e2bc5d9159304f39d92b11afa5784 524 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.9E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS09325 b21e2bc5d9159304f39d92b11afa5784 524 SMART SM00283 266 513 3.2E-76 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS09325 b21e2bc5d9159304f39d92b11afa5784 524 SUPERFAMILY SSF58104 234 514 3.4E-68 T 28-03-2018 hmeg3_RS09325 b21e2bc5d9159304f39d92b11afa5784 524 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 171 1.8E-22 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS03080 f946dc994e1a3f5acd7b7f0bfbd2f60d 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 211 4.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03080 f946dc994e1a3f5acd7b7f0bfbd2f60d 218 SUPERFAMILY SSF161098 13 198 1.57E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03080 f946dc994e1a3f5acd7b7f0bfbd2f60d 218 Gene3D G3DSA:1.10.3720.10 3 218 2.6E-36 T 28-03-2018 hmeg3_RS03080 f946dc994e1a3f5acd7b7f0bfbd2f60d 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 107 1.0E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS06040 42a7d88bb9259db015e5591ef1b7e399 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 1.6E-11 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 hmeg3_RS06040 42a7d88bb9259db015e5591ef1b7e399 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 5.3E-10 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 hmeg3_RS00925 cdf7ac789acb0bdf6b97b3fbc1c5c33a 374 SUPERFAMILY SSF111369 204 286 9.55E-10 T 28-03-2018 hmeg3_RS00925 cdf7ac789acb0bdf6b97b3fbc1c5c33a 374 Gene3D G3DSA:1.20.1600.10 199 331 2.4E-15 T 28-03-2018 hmeg3_RS00925 cdf7ac789acb0bdf6b97b3fbc1c5c33a 374 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 310 2.3E-18 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS00925 cdf7ac789acb0bdf6b97b3fbc1c5c33a 374 SUPERFAMILY SSF111369 68 147 5.75E-8 T 28-03-2018 hmeg3_RS00925 cdf7ac789acb0bdf6b97b3fbc1c5c33a 374 Gene3D G3DSA:2.40.50.100 67 132 2.9E-13 T 28-03-2018 hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 Gene3D G3DSA:3.40.50.2300 1 145 7.9E-36 T 28-03-2018 hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 SUPERFAMILY SSF109604 159 328 7.22E-42 T 28-03-2018 hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 SMART SM00471 164 301 1.1E-9 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 Pfam PF01966 HD domain 170 291 7.7E-20 T 28-03-2018 IPR006674 HD domain hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 Gene3D G3DSA:1.10.3210.10 146 343 1.4E-50 T 28-03-2018 hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 SUPERFAMILY SSF52172 1 141 1.42E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 SMART SM00448 1 115 1.1E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11550 04504cb41255ec12a66745249894ea32 349 Pfam PF00072 Response regulator receiver domain 3 115 1.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 SUPERFAMILY SSF55073 472 635 9.42E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Gene3D G3DSA:3.30.70.270 461 632 4.2E-56 T 28-03-2018 hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 SMART SM00086 413 456 1.4E-8 T 28-03-2018 IPR001610 PAC motif hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 SMART SM00052 643 889 2.1E-108 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 SUPERFAMILY SSF55785 345 459 1.11E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Gene3D G3DSA:3.30.450.20 173 292 0.0017 T 28-03-2018 hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 SMART SM00267 456 633 5.7E-57 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 SUPERFAMILY SSF141868 648 895 1.96E-90 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 368 462 3.1E-7 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Pfam PF00563 EAL domain 649 884 1.6E-73 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Gene3D G3DSA:3.20.20.450 633 893 7.7E-100 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Pfam PF08447 PAS fold 363 449 2.3E-19 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Gene3D G3DSA:3.30.450.20 315 460 8.1E-24 T 28-03-2018 hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Pfam PF00990 Diguanylate cyclase, GGDEF domain 467 629 1.4E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 Gene3D G3DSA:3.30.450.20 55 172 5.9E-5 T 28-03-2018 hmeg3_RS05410 250aff5044d150552e4a5cedd2326d13 917 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 464 631 2.4E-40 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18840 f8ffec5a9e1008b7da1fab43d508d6d0 205 PIRSF PIRSF006305 1 200 1.9E-49 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS18840 f8ffec5a9e1008b7da1fab43d508d6d0 205 Pfam PF02545 Maf-like protein 7 194 4.9E-52 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS18840 f8ffec5a9e1008b7da1fab43d508d6d0 205 Gene3D G3DSA:3.90.950.10 1 195 2.6E-62 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like hmeg3_RS18840 f8ffec5a9e1008b7da1fab43d508d6d0 205 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 193 6.6E-46 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS18840 f8ffec5a9e1008b7da1fab43d508d6d0 205 SUPERFAMILY SSF52972 6 194 1.31E-54 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like hmeg3_RS18840 f8ffec5a9e1008b7da1fab43d508d6d0 205 Hamap MF_00528 Septum formation protein Maf [maf]. 7 199 30.104 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 SUPERFAMILY SSF54966 3 133 3.93E-37 T 28-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 139 424 7.8E-83 T 28-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 184 192 - T 28-03-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 17 129 4.5E-8 T 28-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 SUPERFAMILY SSF51649 136 427 1.96E-91 T 28-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 Gene3D G3DSA:3.20.20.110 135 426 1.7E-98 T 28-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS05695 da9d4136c14dcbf4ccf311028a0e6bc1 429 Gene3D G3DSA:3.30.70.150 1 133 8.1E-38 T 28-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 hmeg3_RS02345 0effc8498dffa38bcbf2205414e9a1f1 240 Gene3D G3DSA:3.40.50.360 22 225 9.4E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS02345 0effc8498dffa38bcbf2205414e9a1f1 240 Pfam PF03358 NADPH-dependent FMN reductase 35 177 1.3E-26 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS02345 0effc8498dffa38bcbf2205414e9a1f1 240 SUPERFAMILY SSF52218 6 227 6.05E-61 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS02345 0effc8498dffa38bcbf2205414e9a1f1 240 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 8 226 8.2E-122 T 28-03-2018 IPR014063 Arsenate resistance ArsH hmeg3_RS24260 b087ebf2979faace02756472404f74cc 255 Pfam PF13230 Glutamine amidotransferases class-II 1 254 2.4E-121 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 hmeg3_RS24260 b087ebf2979faace02756472404f74cc 255 SUPERFAMILY SSF56235 2 251 9.59E-51 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS24260 b087ebf2979faace02756472404f74cc 255 Gene3D G3DSA:3.60.20.10 1 255 9.5E-45 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS14250 a34f018c4b72e784f945b3a763a89f78 261 Gene3D G3DSA:3.40.50.300 5 261 4.2E-60 T 28-03-2018 hmeg3_RS14250 a34f018c4b72e784f945b3a763a89f78 261 SMART SM00382 36 237 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14250 a34f018c4b72e784f945b3a763a89f78 261 Pfam PF00005 ABC transporter 28 187 6.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14250 a34f018c4b72e784f945b3a763a89f78 261 SUPERFAMILY SSF52540 10 259 1.11E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14250 a34f018c4b72e784f945b3a763a89f78 261 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 239 259 4.7E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS00035 e88f44035091dbfca79bedac7a567332 280 Gene3D G3DSA:3.40.190.10 33 143 1.4E-22 T 28-03-2018 hmeg3_RS00035 e88f44035091dbfca79bedac7a567332 280 Gene3D G3DSA:3.40.190.10 144 223 6.3E-11 T 28-03-2018 hmeg3_RS00035 e88f44035091dbfca79bedac7a567332 280 SMART SM00062 43 266 4.9E-34 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS00035 e88f44035091dbfca79bedac7a567332 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 257 1.2E-32 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS00035 e88f44035091dbfca79bedac7a567332 280 SUPERFAMILY SSF53850 44 257 1.42E-44 T 28-03-2018 hmeg3_RS13935 4f4b3b9263cf268cb4e768c6e36f21ca 288 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 92 114 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 hmeg3_RS13935 4f4b3b9263cf268cb4e768c6e36f21ca 288 Pfam PF01066 CDP-alcohol phosphatidyltransferase 51 114 1.8E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 hmeg3_RS13935 4f4b3b9263cf268cb4e768c6e36f21ca 288 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 58 218 8.4E-35 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 hmeg3_RS08535 f9ca42a2dfce225571b140b6e85d2f86 231 Pfam PF01144 Coenzyme A transferase 8 217 3.8E-79 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS08535 f9ca42a2dfce225571b140b6e85d2f86 231 Gene3D G3DSA:3.40.1080.10 1 231 3.7E-96 T 28-03-2018 hmeg3_RS08535 f9ca42a2dfce225571b140b6e85d2f86 231 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS08535 f9ca42a2dfce225571b140b6e85d2f86 231 SUPERFAMILY SSF100950 2 226 2.57E-86 T 28-03-2018 hmeg3_RS08535 f9ca42a2dfce225571b140b6e85d2f86 231 SMART SM00882 5 217 3.2E-89 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS08535 f9ca42a2dfce225571b140b6e85d2f86 231 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 216 4.1E-80 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 Gene3D G3DSA:3.30.1130.10 140 279 1.5E-42 T 28-03-2018 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 PIRSF PIRSF004750 3 279 3.7E-124 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 TIGRFAM TIGR03138 QueF: queuine synthase 8 279 4.1E-122 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 Pfam PF14489 QueF-like protein 191 264 2.1E-26 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 279 153.051 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 SUPERFAMILY SSF55620 181 262 1.7E-8 T 28-03-2018 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 18 127 8.6E-48 T 28-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 hmeg3_RS04355 e552f5dd672d72e750e3df30a12e517b 279 Gene3D G3DSA:3.30.1130.10 18 131 1.2E-40 T 28-03-2018 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 Gene3D G3DSA:1.10.260.40 38 65 3.5E-13 T 28-03-2018 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 SUPERFAMILY SSF46689 2 77 1.03E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 Gene3D G3DSA:1.10.357.10 66 206 4.5E-14 T 28-03-2018 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 202 1.1E-33 T 28-03-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 SUPERFAMILY SSF48498 104 203 1.21E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 Gene3D G3DSA:1.10.10.60 2 37 8.5E-17 T 28-03-2018 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 8.5E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS21120 b4fd946e3cf8ffc5c10828921044f90a 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site hmeg3_RS20050 0a9738d6f4d71d4a34c0eb6d2f085410 342 Pfam PF01300 Telomere recombination 17 202 3.1E-51 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 hmeg3_RS20050 0a9738d6f4d71d4a34c0eb6d2f085410 342 PIRSF PIRSF004930 1 334 5.8E-96 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 hmeg3_RS20050 0a9738d6f4d71d4a34c0eb6d2f085410 342 Gene3D G3DSA:3.90.870.10 2 218 2.6E-70 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain hmeg3_RS20050 0a9738d6f4d71d4a34c0eb6d2f085410 342 SUPERFAMILY SSF55821 5 213 6.1E-55 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain hmeg3_RS20050 0a9738d6f4d71d4a34c0eb6d2f085410 342 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 213 2.5E-50 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 hmeg3_RS20050 0a9738d6f4d71d4a34c0eb6d2f085410 342 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 329 2.8E-20 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 SUPERFAMILY SSF46626 599 726 3.28E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 882 961 5.7E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 SUPERFAMILY SSF56003 100 550 1.88E-35 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 SUPERFAMILY SSF46626 746 853 4.09E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Gene3D G3DSA:3.90.1170.50 9 105 9.7E-6 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Gene3D G3DSA:3.30.365.10 351 556 5.5E-17 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Gene3D G3DSA:1.10.760.10 871 980 1.9E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Gene3D G3DSA:1.10.760.10 580 717 1.5E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Pfam PF00034 Cytochrome c 605 703 4.8E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 99 347 5.0E-6 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Gene3D G3DSA:3.30.365.10 198 350 1.1E-12 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 SUPERFAMILY SSF46626 878 980 8.57E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19240 e53ff032fc288f7d48af6bb36bccd808 993 Gene3D G3DSA:1.10.760.10 731 870 1.8E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06145 21f19fa4dbdffd4300873db4f44fe68f 345 Pfam PF13439 Glycosyltransferase Family 4 14 165 1.3E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 hmeg3_RS06145 21f19fa4dbdffd4300873db4f44fe68f 345 Pfam PF00534 Glycosyl transferases group 1 180 291 1.0E-20 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 hmeg3_RS06145 21f19fa4dbdffd4300873db4f44fe68f 345 SUPERFAMILY SSF53756 1 328 1.1E-67 T 28-03-2018 hmeg3_RS06145 21f19fa4dbdffd4300873db4f44fe68f 345 Gene3D G3DSA:3.40.50.2000 1 168 2.8E-16 T 28-03-2018 hmeg3_RS06145 21f19fa4dbdffd4300873db4f44fe68f 345 Gene3D G3DSA:3.40.50.2000 169 318 7.0E-31 T 28-03-2018 hmeg3_RS11200 a6e6e8b70cd0c95e949a1a70aeea6436 362 SUPERFAMILY SSF53850 35 264 1.6E-39 T 28-03-2018 hmeg3_RS11200 a6e6e8b70cd0c95e949a1a70aeea6436 362 Pfam PF09084 NMT1/THI5 like 59 260 1.7E-21 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS11200 a6e6e8b70cd0c95e949a1a70aeea6436 362 Gene3D G3DSA:3.40.190.10 152 341 7.8E-26 T 28-03-2018 hmeg3_RS11200 a6e6e8b70cd0c95e949a1a70aeea6436 362 Gene3D G3DSA:3.40.190.10 33 151 1.8E-16 T 28-03-2018 hmeg3_RS11200 a6e6e8b70cd0c95e949a1a70aeea6436 362 SMART SM00062 36 264 0.0037 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS13665 7be3956e58771d2d080b83c3c6933b33 487 Pfam PF13476 AAA domain 24 106 4.6E-13 T 28-03-2018 hmeg3_RS13665 7be3956e58771d2d080b83c3c6933b33 487 Gene3D G3DSA:3.40.50.300 194 307 2.6E-7 T 28-03-2018 hmeg3_RS13665 7be3956e58771d2d080b83c3c6933b33 487 Gene3D G3DSA:3.40.50.300 21 188 9.2E-14 T 28-03-2018 hmeg3_RS13665 7be3956e58771d2d080b83c3c6933b33 487 SUPERFAMILY SSF52540 22 275 3.39E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13665 7be3956e58771d2d080b83c3c6933b33 487 SMART SM00382 41 298 5.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS13665 7be3956e58771d2d080b83c3c6933b33 487 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 157 273 5.7E-10 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 Gene3D G3DSA:1.20.120.530 98 253 4.7E-33 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 SUPERFAMILY SSF48008 103 243 2.88E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 Pfam PF07729 FCD domain 108 234 1.2E-25 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 Gene3D G3DSA:1.10.10.10 11 84 2.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 SUPERFAMILY SSF46785 12 87 1.05E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 SMART SM00345 24 83 3.0E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 SMART SM00895 107 235 2.7E-24 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 83 9.2E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 1.7E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS15570 6cfb65bfce79cd2e6b74d89c05993d1f 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 1.7E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 SUPERFAMILY SSF82114 179 314 1.61E-39 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 17 312 2.7E-88 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 SUPERFAMILY SSF52374 15 179 1.86E-35 T 28-03-2018 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 Gene3D G3DSA:2.40.30.30 184 324 1.1E-35 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 PIRSF PIRSF004491 1 317 8.9E-99 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 SMART SM00904 187 312 1.3E-55 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 Pfam PF01687 Riboflavin kinase 188 311 4.6E-34 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 Gene3D G3DSA:3.40.50.620 1 183 4.7E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS06670 a9c2e4c8b5d08918adad6b9d5c625345 325 Pfam PF06574 FAD synthetase 11 170 8.6E-55 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 hmeg3_RS20235 1a2d037ee7cb15a5481b24dc38f16cab 844 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 524 833 1.7E-64 T 28-03-2018 IPR007296 Domain of unknown function DUF403 hmeg3_RS20235 1a2d037ee7cb15a5481b24dc38f16cab 844 Pfam PF14403 Circularly permuted ATP-grasp type 2 82 462 2.3E-156 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 hmeg3_RS20235 1a2d037ee7cb15a5481b24dc38f16cab 844 SUPERFAMILY SSF56059 327 460 2.15E-21 T 28-03-2018 hmeg3_RS20235 1a2d037ee7cb15a5481b24dc38f16cab 844 SUPERFAMILY SSF56059 25 220 2.15E-21 T 28-03-2018 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 PRINTS PR00604 Class IA and IB cytochrome C signature 50 65 2.9E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 PRINTS PR00604 Class IA and IB cytochrome C signature 66 76 2.9E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 PRINTS PR00604 Class IA and IB cytochrome C signature 80 96 2.9E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 PRINTS PR00604 Class IA and IB cytochrome C signature 99 109 2.9E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 PRINTS PR00604 Class IA and IB cytochrome C signature 116 124 2.9E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 PRINTS PR00604 Class IA and IB cytochrome C signature 37 44 2.9E-16 T 28-03-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 SUPERFAMILY SSF46626 26 124 5.0E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 Gene3D G3DSA:1.10.760.10 18 126 2.3E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS05015 b5a8c16a176e4bdf95874f80c85df2a7 126 Pfam PF00034 Cytochrome c 28 124 2.2E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS12905 26e74367d4df817a8f10c156fc9760db 396 Gene3D G3DSA:3.40.50.10540 2 396 2.8E-126 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS12905 26e74367d4df817a8f10c156fc9760db 396 Pfam PF02515 CoA-transferase family III 8 373 1.3E-106 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 hmeg3_RS12905 26e74367d4df817a8f10c156fc9760db 396 SUPERFAMILY SSF89796 2 396 4.45E-121 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS06575 e09a06e7ae45dd9fcab76726e911c1a7 257 SUPERFAMILY SSF46626 142 231 1.01E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06575 e09a06e7ae45dd9fcab76726e911c1a7 257 PIRSF PIRSF000005 10 234 1.9E-60 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 hmeg3_RS06575 e09a06e7ae45dd9fcab76726e911c1a7 257 SUPERFAMILY SSF46626 61 133 1.01E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06575 e09a06e7ae45dd9fcab76726e911c1a7 257 Gene3D G3DSA:1.10.760.10 26 128 1.3E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06575 e09a06e7ae45dd9fcab76726e911c1a7 257 Gene3D G3DSA:1.10.760.10 132 232 2.2E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS22195 f54cb2f91b7ba30e6a81e6eb7f5ea069 330 SUPERFAMILY SSF53187 13 322 4.3E-52 T 28-03-2018 hmeg3_RS22195 f54cb2f91b7ba30e6a81e6eb7f5ea069 330 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 44 238 2.1E-13 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 hmeg3_RS22195 f54cb2f91b7ba30e6a81e6eb7f5ea069 330 Gene3D G3DSA:3.40.630.10 38 274 1.8E-10 T 28-03-2018 hmeg3_RS12540 2b30c4c18f16cdf034b9128358c5aa6d 422 SUPERFAMILY SSF53383 9 395 6.65E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS12540 2b30c4c18f16cdf034b9128358c5aa6d 422 Gene3D G3DSA:3.90.1150.10 303 398 9.0E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12540 2b30c4c18f16cdf034b9128358c5aa6d 422 Gene3D G3DSA:3.40.640.10 51 302 1.6E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS12540 2b30c4c18f16cdf034b9128358c5aa6d 422 Pfam PF00155 Aminotransferase class I and II 37 387 6.2E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS10155 7c76a235d97d293acb8ed85e7f2ed202 438 Pfam PF05231 MASE1 11 294 4.6E-30 T 28-03-2018 IPR007895 MASE1 hmeg3_RS10155 7c76a235d97d293acb8ed85e7f2ed202 438 Gene3D G3DSA:3.30.450.20 279 431 1.4E-8 T 28-03-2018 hmeg3_RS10155 7c76a235d97d293acb8ed85e7f2ed202 438 SUPERFAMILY SSF55785 317 425 1.52E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.5E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 PRINTS PR00050 Cold shock protein signature 25 34 5.0E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 PRINTS PR00050 Cold shock protein signature 40 58 5.0E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 PRINTS PR00050 Cold shock protein signature 4 19 5.0E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 SUPERFAMILY SSF50249 1 66 9.21E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 Gene3D G3DSA:2.40.50.140 1 67 1.4E-29 T 28-03-2018 hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 SMART SM00357 3 67 4.7E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 hmeg3_RS08505 3115adc6aa7d32505c48c14e2580b662 67 PIRSF PIRSF002599 1 67 5.7E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 hmeg3_RS16925 307641d17aa2c0e156e4846496e1e179 162 SUPERFAMILY SSF55729 3 152 3.14E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS16925 307641d17aa2c0e156e4846496e1e179 162 Pfam PF00583 Acetyltransferase (GNAT) family 59 148 2.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS16925 307641d17aa2c0e156e4846496e1e179 162 Gene3D G3DSA:3.40.630.30 2 156 7.7E-23 T 28-03-2018 hmeg3_RS14665 5b229153f0fc410973abcf952eeebb96 66 Gene3D G3DSA:3.30.70.100 2 63 3.0E-15 T 28-03-2018 hmeg3_RS14665 5b229153f0fc410973abcf952eeebb96 66 SUPERFAMILY SSF55008 2 64 3.01E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS14665 5b229153f0fc410973abcf952eeebb96 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 hmeg3_RS14665 5b229153f0fc410973abcf952eeebb96 66 Pfam PF00403 Heavy-metal-associated domain 4 62 2.5E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 Pfam PF01230 HIT domain 12 116 1.7E-25 T 28-03-2018 IPR001310 Histidine triad (HIT) protein hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 SUPERFAMILY SSF54197 2 115 1.7E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 ProSitePatterns PS00892 HIT domain signature. 96 114 - T 28-03-2018 IPR019808 Histidine triad, conserved site hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 PRINTS PR00332 Histidine triad family signature 26 44 6.6E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 PRINTS PR00332 Histidine triad family signature 5 21 6.6E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 PRINTS PR00332 Histidine triad family signature 103 113 6.6E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein hmeg3_RS03525 b442ac775f2cb06ab30c3297999de9c1 127 Gene3D G3DSA:3.30.428.10 1 121 5.5E-35 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 Gene3D G3DSA:2.30.33.40 1 95 8.0E-39 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 SMART SM00883 2 94 4.5E-57 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 PRINTS PR00297 10kDa chaperonin signature 3 18 3.9E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 PRINTS PR00297 10kDa chaperonin signature 25 46 3.9E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 PRINTS PR00297 10kDa chaperonin signature 81 94 3.9E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 PRINTS PR00297 10kDa chaperonin signature 60 72 3.9E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 SUPERFAMILY SSF50129 1 95 1.05E-33 T 28-03-2018 IPR011032 GroES-like hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.618 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS05830 a87e0edb79086a0c9c5690eb39fcc4d4 96 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 2.4E-33 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 hmeg3_RS18560 1a7974c0534167ccb4cd98f9c5745944 468 Gene3D G3DSA:3.40.50.1820 1 294 2.6E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS18560 1a7974c0534167ccb4cd98f9c5745944 468 Pfam PF11678 Protein of unknown function (DUF3274) 366 426 1.0E-4 T 28-03-2018 IPR021692 Protein of unknown function DUF3274 hmeg3_RS18560 1a7974c0534167ccb4cd98f9c5745944 468 SUPERFAMILY SSF53474 4 184 2.05E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 Pfam PF00814 Glycoprotease family 24 309 2.2E-99 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 308 1.0E-116 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 SUPERFAMILY SSF53067 3 122 3.43E-28 T 28-03-2018 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 336 62.629 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 SUPERFAMILY SSF53067 102 311 7.59E-46 T 28-03-2018 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 5.7E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 5.7E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 5.7E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 5.7E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 265 274 5.7E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 5.7E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 Gene3D G3DSA:3.30.420.40 145 292 1.2E-16 T 28-03-2018 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 315 1.1E-134 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 hmeg3_RS19670 fa35c0d3461a0c0822e4ceecc84ee381 343 Gene3D G3DSA:3.30.420.40 1 144 1.1E-37 T 28-03-2018 hmeg3_RS16285 9b0c6bf4c5dfbe095880920faf83229e 305 SUPERFAMILY SSF161098 97 284 2.49E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS16285 9b0c6bf4c5dfbe095880920faf83229e 305 Gene3D G3DSA:1.10.3720.10 28 292 9.4E-45 T 28-03-2018 hmeg3_RS16285 9b0c6bf4c5dfbe095880920faf83229e 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 303 1.6E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS16285 9b0c6bf4c5dfbe095880920faf83229e 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 79 1.2E-14 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS20300 a6151a73f43f9c6f655c4b0ce5522b62 168 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 96 107 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 hmeg3_RS20300 a6151a73f43f9c6f655c4b0ce5522b62 168 SUPERFAMILY SSF55083 11 150 1.96E-48 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 hmeg3_RS20300 a6151a73f43f9c6f655c4b0ce5522b62 168 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 14 140 2.4E-36 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 hmeg3_RS20300 a6151a73f43f9c6f655c4b0ce5522b62 168 Gene3D G3DSA:3.30.70.560 9 166 2.5E-52 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 hmeg3_RS20300 a6151a73f43f9c6f655c4b0ce5522b62 168 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 13 140 5.0E-40 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 hmeg3_RS00190 d96685ffcebf72481186812dfb6dc05c 446 SUPERFAMILY SSF51679 6 441 3.66E-135 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS00190 d96685ffcebf72481186812dfb6dc05c 446 Gene3D G3DSA:3.20.20.30 1 446 1.2E-106 T 28-03-2018 hmeg3_RS00190 d96685ffcebf72481186812dfb6dc05c 446 Pfam PF00296 Luciferase-like monooxygenase 21 391 1.5E-60 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS00190 d96685ffcebf72481186812dfb6dc05c 446 PIRSF PIRSF000337 5 446 4.9E-167 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS00190 d96685ffcebf72481186812dfb6dc05c 446 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 11 435 1.4E-174 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Pfam PF00873 AcrB/AcrD/AcrF family 1 1028 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 624 638 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 PRINTS PR00702 Acriflavin resistance protein family signature 556 573 8.0E-107 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Gene3D G3DSA:3.30.70.1430 571 671 2.3E-22 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Gene3D G3DSA:3.30.70.1430 38 141 2.5E-27 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82866 834 1029 8.76E-46 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1046 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Gene3D G3DSA:3.30.2090.10 180 273 5.0E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82693 38 133 2.67E-25 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82866 296 499 1.7E-46 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82693 569 674 9.94E-28 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82714 725 811 6.28E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82693 135 182 1.88E-21 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82693 274 331 1.88E-21 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82714 182 271 3.92E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Gene3D G3DSA:3.30.70.1440 675 771 8.0E-18 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Gene3D G3DSA:1.20.1640.10 829 1032 9.1E-41 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 Gene3D G3DSA:1.20.1640.10 274 500 4.7E-43 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82693 675 724 1.75E-26 T 28-03-2018 hmeg3_RS06485 7daf73440bc39f58281ebd68c6d676aa 1055 SUPERFAMILY SSF82693 811 859 1.75E-26 T 28-03-2018 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 SUPERFAMILY SSF56634 108 611 2.88E-222 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 Pfam PF01965 DJ-1/PfpI family 643 753 2.2E-9 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 Gene3D G3DSA:2.40.180.10 102 482 1.1E-166 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PIRSF PIRSF038927 91 800 0.0 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 Pfam PF00199 Catalase 127 511 1.1E-180 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 SUPERFAMILY SSF52317 641 754 2.17E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 ProSitePatterns PS00438 Catalase proximal active site signature. 163 179 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PRINTS PR00067 Catalase signature 412 439 4.1E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PRINTS PR00067 Catalase signature 243 261 4.1E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PRINTS PR00067 Catalase signature 224 241 4.1E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PRINTS PR00067 Catalase signature 140 163 4.1E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PRINTS PR00067 Catalase signature 444 470 4.1E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 PRINTS PR00067 Catalase signature 203 221 4.1E-70 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 SMART SM01060 127 515 4.4E-282 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 Pfam PF06628 Catalase-related immune-responsive 541 604 2.7E-20 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 hmeg3_RS06445 4925327c3284b7657fc89113a3b450ac 801 Gene3D G3DSA:3.40.50.880 640 798 4.6E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS02340 b2b56f5c9715d2934035d0fc03e2c3ff 293 Pfam PF00892 EamA-like transporter family 14 138 8.5E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS02340 b2b56f5c9715d2934035d0fc03e2c3ff 293 Pfam PF00892 EamA-like transporter family 150 288 1.2E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS02340 b2b56f5c9715d2934035d0fc03e2c3ff 293 SUPERFAMILY SSF103481 56 139 5.89E-11 T 28-03-2018 hmeg3_RS02340 b2b56f5c9715d2934035d0fc03e2c3ff 293 SUPERFAMILY SSF103481 211 288 7.06E-7 T 28-03-2018 hmeg3_RS04525 4d0ee56d08c66a5d8bc4a14f4a7cd67f 390 Gene3D G3DSA:3.90.850.10 71 367 3.4E-24 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS04525 4d0ee56d08c66a5d8bc4a14f4a7cd67f 390 SUPERFAMILY SSF56529 160 365 3.53E-23 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS01180 f25bbf64336984ba8df19ca43794beed 233 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS01180 f25bbf64336984ba8df19ca43794beed 233 SMART SM00382 29 209 1.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01180 f25bbf64336984ba8df19ca43794beed 233 SUPERFAMILY SSF52540 4 223 6.99E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01180 f25bbf64336984ba8df19ca43794beed 233 Gene3D G3DSA:3.40.50.300 1 230 1.8E-49 T 28-03-2018 hmeg3_RS01180 f25bbf64336984ba8df19ca43794beed 233 Pfam PF00005 ABC transporter 20 159 8.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS13630 b1f55fbec8bceecba533a4fe803ff8f2 573 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS13630 b1f55fbec8bceecba533a4fe803ff8f2 573 SUPERFAMILY SSF143975 14 376 9.94E-116 T 28-03-2018 hmeg3_RS13630 b1f55fbec8bceecba533a4fe803ff8f2 573 Pfam PF00920 Dehydratase family 41 556 3.4E-173 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS13630 b1f55fbec8bceecba533a4fe803ff8f2 573 SUPERFAMILY SSF52016 377 563 5.02E-55 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 Gene3D G3DSA:1.10.260.40 20 72 4.9E-17 T 28-03-2018 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 21 66 3.6E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 Gene3D G3DSA:3.40.50.2300 194 333 9.3E-29 T 28-03-2018 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 Gene3D G3DSA:3.40.50.2300 73 193 5.1E-25 T 28-03-2018 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 Pfam PF13377 Periplasmic binding protein-like domain 186 350 6.7E-24 T 28-03-2018 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 SUPERFAMILY SSF47413 20 77 3.43E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 SMART SM00354 19 89 1.8E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS24580 bf535ebd254f8fb0ec76c92987c03c0d 350 SUPERFAMILY SSF53822 76 333 2.9E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS00755 7c9fb1c5a2c060ea62ebfa215d83c49e 430 Pfam PF04348 LppC putative lipoprotein 47 421 1.3E-32 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA hmeg3_RS00755 7c9fb1c5a2c060ea62ebfa215d83c49e 430 SUPERFAMILY SSF53822 70 425 2.03E-29 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS00755 7c9fb1c5a2c060ea62ebfa215d83c49e 430 Gene3D G3DSA:3.40.50.2300 213 404 1.3E-10 T 28-03-2018 hmeg3_RS00755 7c9fb1c5a2c060ea62ebfa215d83c49e 430 Gene3D G3DSA:3.40.50.2300 70 212 1.8E-8 T 28-03-2018 hmeg3_RS24480 275b5a71b02f1162bff655f238d77e2f 303 SUPERFAMILY SSF46689 20 92 1.97E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS24480 275b5a71b02f1162bff655f238d77e2f 303 Gene3D G3DSA:1.10.10.10 19 139 7.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24480 275b5a71b02f1162bff655f238d77e2f 303 Gene3D G3DSA:3.40.50.10490 140 278 1.1E-15 T 28-03-2018 hmeg3_RS24480 275b5a71b02f1162bff655f238d77e2f 303 Pfam PF01418 Helix-turn-helix domain, rpiR family 24 88 9.0E-7 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 hmeg3_RS24480 275b5a71b02f1162bff655f238d77e2f 303 Pfam PF01380 SIS domain 145 269 1.4E-12 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS24480 275b5a71b02f1162bff655f238d77e2f 303 SUPERFAMILY SSF53697 117 275 3.56E-18 T 28-03-2018 hmeg3_RS02870 39c21d2c7a4a3b19e24dfc2a33ede54a 281 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 6 270 1.3E-30 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 hmeg3_RS02870 39c21d2c7a4a3b19e24dfc2a33ede54a 281 PIRSF PIRSF026649 1 277 1.9E-70 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 hmeg3_RS24430 bef2fe40c34015c2d3cc3e195385b717 304 SUPERFAMILY SSF161098 96 285 2.49E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24430 bef2fe40c34015c2d3cc3e195385b717 304 Gene3D G3DSA:1.10.3720.10 29 292 1.2E-46 T 28-03-2018 hmeg3_RS24430 bef2fe40c34015c2d3cc3e195385b717 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 72 9.6E-13 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS24430 bef2fe40c34015c2d3cc3e195385b717 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 302 1.4E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 Gene3D G3DSA:3.40.50.970 357 549 9.4E-27 T 28-03-2018 hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 SUPERFAMILY SSF52518 370 542 2.78E-37 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 330 3.0E-20 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 540 2.5E-28 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 SUPERFAMILY SSF52467 166 354 3.52E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 SUPERFAMILY SSF52518 10 190 4.02E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 181 6.5E-43 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 Gene3D G3DSA:3.40.50.970 4 196 1.7E-40 T 28-03-2018 hmeg3_RS00130 ee8e95a7dcc58e59339f975e22468337 581 Gene3D G3DSA:3.40.50.1220 197 356 4.4E-26 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 610 47.529 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 SUPERFAMILY SSF82866 406 604 4.71E-39 T 28-03-2018 hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 SUPERFAMILY SSF82866 341 360 4.71E-39 T 28-03-2018 hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 Pfam PF07549 SecD/SecF GG Motif 125 149 7.9E-6 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 Pfam PF13721 SecD export protein N-terminal TM region 1 111 1.4E-34 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 132 595 1.4E-136 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 Pfam PF02355 Protein export membrane protein 428 599 1.8E-22 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 Gene3D G3DSA:1.20.1640.10 390 602 2.8E-29 T 28-03-2018 hmeg3_RS05070 4b0c5a5b46385c4f78a6d69e8f3a6e37 631 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 356 589 3.6E-70 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 Gene3D G3DSA:3.40.50.1820 125 429 2.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 201 430 5.3E-55 T 28-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 16 135 2.6E-32 T 28-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 PIRSF PIRSF016521 1 437 7.7E-101 T 28-03-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 SUPERFAMILY SSF53474 68 256 2.32E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 SUPERFAMILY SSF53474 415 426 2.32E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11110 973caf6973cb6d7328f90168b033c3fd 437 SUPERFAMILY SSF53474 289 386 2.32E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 Pfam PF01979 Amidohydrolase family 246 424 7.3E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 428 31.621 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 Gene3D G3DSA:3.20.20.140 71 392 7.5E-75 T 28-03-2018 hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 Gene3D G3DSA:2.30.40.10 1 70 1.3E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 SUPERFAMILY SSF51556 56 372 2.6E-83 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 SUPERFAMILY SSF51338 1 55 8.34E-30 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 SUPERFAMILY SSF51338 371 427 8.34E-30 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS21375 805f22b3c6d53f61ccf5bf5971136ffa 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 426 1.8E-94 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 SMART SM00283 264 511 1.1E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 184 1.5E-31 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 Gene3D G3DSA:1.20.120.30 24 185 9.1E-29 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 Pfam PF00672 HAMP domain 211 259 8.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 SMART SM00304 211 263 7.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 SUPERFAMILY SSF58104 231 512 2.49E-76 T 28-03-2018 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 Gene3D G3DSA:1.10.287.950 323 515 6.8E-50 T 28-03-2018 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 Gene3D G3DSA:1.10.287.1060 234 322 0.044 T 28-03-2018 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 478 9.2E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 12 37 2.9E-62 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 2.9E-62 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 188 208 2.9E-62 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 2.9E-62 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 2.9E-62 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS04065 436d84c3bb0e328375b82fe86a077c19 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 2.9E-62 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 SMART SM00388 141 205 2.3E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 358 6.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 SUPERFAMILY SSF47384 124 205 6.47E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 Gene3D G3DSA:3.30.565.10 209 364 3.2E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 SUPERFAMILY SSF55874 194 358 6.81E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 Gene3D G3DSA:1.10.287.130 116 200 8.1E-8 T 28-03-2018 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 3.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 338 3.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 299 3.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 313 3.9E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 201 9.1E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS06840 b54596c4df041a4ca7bf4c2f2684480b 364 SMART SM00387 249 360 2.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS22425 2340c751d9e60a739719e01bd252cf65 461 Gene3D G3DSA:3.40.50.2000 1 242 2.9E-60 T 28-03-2018 hmeg3_RS22425 2340c751d9e60a739719e01bd252cf65 461 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 456 2.1E-174 T 28-03-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 hmeg3_RS22425 2340c751d9e60a739719e01bd252cf65 461 SUPERFAMILY SSF53756 2 456 2.46E-148 T 28-03-2018 hmeg3_RS22425 2340c751d9e60a739719e01bd252cf65 461 Gene3D G3DSA:3.40.50.2000 243 440 4.5E-46 T 28-03-2018 hmeg3_RS22425 2340c751d9e60a739719e01bd252cf65 461 Pfam PF00982 Glycosyltransferase family 20 16 455 1.8E-131 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 hmeg3_RS15310 11d43e891f51529229343f0c8ac1158f 311 Gene3D G3DSA:3.40.50.620 4 309 2.8E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS15310 11d43e891f51529229343f0c8ac1158f 311 PIRSF PIRSF002936 9 311 1.3E-140 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 hmeg3_RS15310 11d43e891f51529229343f0c8ac1158f 311 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 18 311 1.5E-125 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 hmeg3_RS15310 11d43e891f51529229343f0c8ac1158f 311 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 264 1.7E-46 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 hmeg3_RS15310 11d43e891f51529229343f0c8ac1158f 311 SUPERFAMILY SSF52402 13 219 4.89E-64 T 28-03-2018 hmeg3_RS22230 ac859532ed27426c2a652aa876fb0f2f 255 Pfam PF04773 FecR protein 72 159 5.6E-8 T 28-03-2018 IPR006860 FecR protein hmeg3_RS17050 7272a81cb1889f85123c02dc07226c92 259 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 3 253 2.6E-117 T 28-03-2018 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 hmeg3_RS17050 7272a81cb1889f85123c02dc07226c92 259 SUPERFAMILY SSF51658 1 255 1.22E-84 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain hmeg3_RS17050 7272a81cb1889f85123c02dc07226c92 259 Pfam PF01261 Xylose isomerase-like TIM barrel 21 218 2.6E-33 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain hmeg3_RS17050 7272a81cb1889f85123c02dc07226c92 259 Gene3D G3DSA:3.20.20.150 1 257 2.8E-58 T 28-03-2018 hmeg3_RS17050 7272a81cb1889f85123c02dc07226c92 259 PIRSF PIRSF006241 1 258 1.2E-96 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 hmeg3_RS06230 c79120dcbb0e398970ec5a5feb7f4fcd 467 Gene3D G3DSA:3.40.309.10 256 447 3.5E-68 T 28-03-2018 hmeg3_RS06230 c79120dcbb0e398970ec5a5feb7f4fcd 467 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 265 276 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS06230 c79120dcbb0e398970ec5a5feb7f4fcd 467 Gene3D G3DSA:3.40.605.10 3 255 3.4E-66 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS06230 c79120dcbb0e398970ec5a5feb7f4fcd 467 Pfam PF00171 Aldehyde dehydrogenase family 13 461 2.3E-135 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS06230 c79120dcbb0e398970ec5a5feb7f4fcd 467 SUPERFAMILY SSF53720 12 464 2.62E-137 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS24140 f798f63a93c71c235e769342e45a9bef 232 SUPERFAMILY SSF55920 22 226 6.02E-25 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS24140 f798f63a93c71c235e769342e45a9bef 232 Pfam PF00557 Metallopeptidase family M24 24 200 6.9E-15 T 28-03-2018 IPR000994 Peptidase M24 hmeg3_RS24140 f798f63a93c71c235e769342e45a9bef 232 Gene3D G3DSA:3.90.230.10 19 228 7.2E-17 T 28-03-2018 hmeg3_RS01365 256f1e6055636ec9eed208a9d6976d10 127 Gene3D G3DSA:1.10.287.180 60 96 0.23 T 28-03-2018 hmeg3_RS01365 256f1e6055636ec9eed208a9d6976d10 127 Pfam PF13663 Domain of unknown function (DUF4148) 4 58 3.3E-13 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS01365 256f1e6055636ec9eed208a9d6976d10 127 Pfam PF13663 Domain of unknown function (DUF4148) 63 93 5.4E-10 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 Pfam PF00107 Zinc-binding dehydrogenase 179 305 2.4E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 136 4.0E-32 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 SMART SM00829 14 339 6.6E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 Gene3D G3DSA:3.40.50.720 172 289 9.7E-27 T 28-03-2018 hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 SUPERFAMILY SSF51735 142 310 3.94E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 SUPERFAMILY SSF50129 3 184 4.26E-54 T 28-03-2018 IPR011032 GroES-like hmeg3_RS11490 e53c7dd9c0a50f7143ecead00f611230 342 Gene3D G3DSA:3.90.180.10 1 171 3.1E-61 T 28-03-2018 hmeg3_RS21560 374490880148ed9e24dac8c77d226e4b 620 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 40 165 4.5E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component hmeg3_RS21560 374490880148ed9e24dac8c77d226e4b 620 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 210 614 1.4E-97 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit hmeg3_RS21560 374490880148ed9e24dac8c77d226e4b 620 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 215 616 9.0E-89 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS21940 978a72a4dd9ffe01dac2f81f43545775 290 SUPERFAMILY SSF52540 47 195 1.52E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21940 978a72a4dd9ffe01dac2f81f43545775 290 SMART SM00382 86 204 0.0011 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21940 978a72a4dd9ffe01dac2f81f43545775 290 Pfam PF05673 Protein of unknown function (DUF815) 35 287 2.9E-106 T 28-03-2018 IPR008533 Domain of unknown function DUF815 hmeg3_RS21940 978a72a4dd9ffe01dac2f81f43545775 290 Gene3D G3DSA:3.40.50.300 69 201 1.4E-12 T 28-03-2018 hmeg3_RS22545 7be01e486161fe4274d0026157b0b843 678 Gene3D G3DSA:2.40.170.20 178 678 1.8E-47 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22545 7be01e486161fe4274d0026157b0b843 678 SUPERFAMILY SSF56935 46 678 3.66E-85 T 28-03-2018 hmeg3_RS22545 7be01e486161fe4274d0026157b0b843 678 Gene3D G3DSA:2.170.130.10 37 169 7.6E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22545 7be01e486161fe4274d0026157b0b843 678 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 163 2.3E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS22545 7be01e486161fe4274d0026157b0b843 678 Pfam PF00593 TonB dependent receptor 306 675 1.7E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 266 7.2E-51 T 28-03-2018 hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 8.6E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 8.6E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.6E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 8.6E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 8.6E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 8.6E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 Gene3D G3DSA:3.40.50.720 1 268 1.3E-65 T 28-03-2018 hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 SUPERFAMILY SSF51735 11 267 1.49E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 156 0.0095 T 28-03-2018 hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 4.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21295 e8b16f94af79c2b6224301f1cf6854b8 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 4.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 SUPERFAMILY SSF111369 58 119 1.44E-9 T 28-03-2018 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 Gene3D G3DSA:2.40.50.100 237 366 6.1E-10 T 28-03-2018 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 Gene3D G3DSA:2.40.50.100 64 155 1.2E-9 T 28-03-2018 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 75 95 1.2E-6 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 366 381 1.2E-6 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 292 316 1.2E-6 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 260 281 1.2E-6 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 Pfam PF13533 Biotin-lipoyl like 63 111 4.6E-13 T 28-03-2018 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 Pfam PF13437 HlyD family secretion protein 248 364 8.8E-16 T 28-03-2018 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 Gene3D G3DSA:1.10.287.470 156 197 9.0E-11 T 28-03-2018 hmeg3_RS00960 9811fe6116514d485b76a633fe29b08b 421 SUPERFAMILY SSF111369 200 298 7.85E-9 T 28-03-2018 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 SUPERFAMILY SSF52413 297 409 3.14E-27 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 412 1.9E-19 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 Gene3D G3DSA:3.40.50.720 220 425 3.1E-57 T 28-03-2018 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 SUPERFAMILY SSF48179 197 288 7.82E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 176 3.5E-30 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 SMART SM00984 313 413 7.5E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 PIRSF PIRSF500136 1 426 6.0E-143 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 407 1.3E-116 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 SUPERFAMILY SSF51735 4 189 1.69E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 286 2.5E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 Gene3D G3DSA:3.40.50.720 3 195 2.0E-36 T 28-03-2018 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 PIRSF PIRSF000124 2 426 4.4E-57 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS01910 9851c46ec14cb8ea060ca11bdd75ac11 426 Gene3D G3DSA:1.20.5.170 197 219 3.0E-10 T 28-03-2018 hmeg3_RS06210 273fdc39d2f3cf714acfc9138186132e 213 Gene3D G3DSA:3.40.30.10 1 83 1.6E-18 T 28-03-2018 hmeg3_RS06210 273fdc39d2f3cf714acfc9138186132e 213 Pfam PF00043 Glutathione S-transferase, C-terminal domain 126 195 7.3E-9 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS06210 273fdc39d2f3cf714acfc9138186132e 213 Gene3D G3DSA:1.20.1050.10 84 211 1.6E-21 T 28-03-2018 hmeg3_RS06210 273fdc39d2f3cf714acfc9138186132e 213 SUPERFAMILY SSF47616 89 211 5.01E-25 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS06210 273fdc39d2f3cf714acfc9138186132e 213 SUPERFAMILY SSF52833 1 78 4.03E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS06210 273fdc39d2f3cf714acfc9138186132e 213 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 73 2.2E-13 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS12915 054c3df954d9536bbcc571419e71e763 286 SUPERFAMILY SSF54637 173 285 2.37E-14 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS12915 054c3df954d9536bbcc571419e71e763 286 Gene3D G3DSA:3.10.129.10 164 286 1.6E-19 T 28-03-2018 hmeg3_RS12915 054c3df954d9536bbcc571419e71e763 286 Pfam PF13452 N-terminal half of MaoC dehydratase 79 139 2.8E-6 T 28-03-2018 hmeg3_RS12915 054c3df954d9536bbcc571419e71e763 286 SUPERFAMILY SSF54637 45 155 7.46E-6 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS12915 054c3df954d9536bbcc571419e71e763 286 Gene3D G3DSA:3.10.129.10 12 163 2.4E-18 T 28-03-2018 hmeg3_RS11710 867311215b6f243a0704bdae1d81e047 264 Gene3D G3DSA:3.40.50.1820 2 251 1.8E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11710 867311215b6f243a0704bdae1d81e047 264 SUPERFAMILY SSF53474 18 241 3.95E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS11710 867311215b6f243a0704bdae1d81e047 264 Pfam PF00975 Thioesterase domain 23 239 1.5E-34 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 SUPERFAMILY SSF56349 126 314 2.0E-53 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 26 317 53.229 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 30 316 1.4E-110 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 24 317 57.678 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 SUPERFAMILY SSF47823 26 119 1.65E-27 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 Gene3D G3DSA:1.10.443.10 132 311 2.1E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 28 109 1.1E-16 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 Gene3D G3DSA:1.10.150.130 25 131 1.0E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS19685 89e3dd44d73879ebc72b5bef74316687 317 Pfam PF00589 Phage integrase family 131 302 6.1E-47 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS02965 99cd384c6b45559aaef02e8e06eefd3f 88 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 84 1.2E-24 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 hmeg3_RS02965 99cd384c6b45559aaef02e8e06eefd3f 88 Pfam PF03776 Septum formation topological specificity factor MinE 14 83 1.2E-20 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 hmeg3_RS02965 99cd384c6b45559aaef02e8e06eefd3f 88 SUPERFAMILY SSF55229 35 85 6.93E-13 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 hmeg3_RS02965 99cd384c6b45559aaef02e8e06eefd3f 88 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 85 16.58 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 hmeg3_RS02965 99cd384c6b45559aaef02e8e06eefd3f 88 Gene3D G3DSA:3.30.1070.10 1 84 3.1E-22 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 8.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 SMART SM00895 82 205 6.0E-15 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 Gene3D G3DSA:1.20.120.530 69 222 9.0E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 SMART SM00345 14 72 3.6E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 Pfam PF07729 FCD domain 83 204 9.4E-21 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 Gene3D G3DSA:1.10.10.10 1 68 4.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 SUPERFAMILY SSF46785 10 76 6.54E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11170 d672a32ba1a93f43f26ceeb9c6291ca2 228 SUPERFAMILY SSF48008 78 210 4.45E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00096 Glutamine amidotransferase superfamily signature 271 282 6.4E-10 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00096 Glutamine amidotransferase superfamily signature 243 252 6.4E-10 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00096 Glutamine amidotransferase superfamily signature 356 369 6.4E-10 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 SUPERFAMILY SSF52021 11 152 1.1E-55 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 10 385 47.426 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 12 139 3.3E-51 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 313 324 5.1E-40 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 254 5.1E-40 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 271 287 5.1E-40 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 288 305 5.1E-40 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 201 215 5.1E-40 T 28-03-2018 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 Pfam PF00117 Glutamine amidotransferase class-I 204 379 4.2E-49 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 Gene3D G3DSA:3.40.50.880 162 386 1.6E-66 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 12 383 1.1E-142 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 Gene3D G3DSA:3.50.30.20 9 161 1.4E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 SUPERFAMILY SSF52317 163 383 1.35E-62 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS06520 4220d466cd16171b9619971084882c28 387 SMART SM01097 10 140 7.9E-86 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS03385 1bce0d6e03062c7d0c965d4d501ac903 85 Gene3D G3DSA:3.30.70.20 1 20 9.8E-5 T 28-03-2018 hmeg3_RS03385 1bce0d6e03062c7d0c965d4d501ac903 85 Gene3D G3DSA:3.30.70.20 50 78 0.09 T 28-03-2018 hmeg3_RS03385 1bce0d6e03062c7d0c965d4d501ac903 85 SUPERFAMILY SSF54862 4 76 7.07E-19 T 28-03-2018 hmeg3_RS03385 1bce0d6e03062c7d0c965d4d501ac903 85 Pfam PF12838 4Fe-4S dicluster domain 9 57 1.6E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS03385 1bce0d6e03062c7d0c965d4d501ac903 85 Gene3D G3DSA:3.30.70.20 21 49 9.0E-9 T 28-03-2018 hmeg3_RS03385 1bce0d6e03062c7d0c965d4d501ac903 85 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS04035 400167c56dcb73923957a757c2febf83 185 Pfam PF03968 OstA-like protein 34 152 2.7E-20 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal hmeg3_RS04035 400167c56dcb73923957a757c2febf83 185 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 5 178 24.796 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 hmeg3_RS04035 400167c56dcb73923957a757c2febf83 185 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 23 177 3.0E-35 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 hmeg3_RS04035 400167c56dcb73923957a757c2febf83 185 Gene3D G3DSA:2.60.450.10 23 175 5.7E-19 T 28-03-2018 hmeg3_RS12780 6cf9d879991559643394a8ec04eb6487 98 SMART SM00530 10 65 8.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS12780 6cf9d879991559643394a8ec04eb6487 98 SUPERFAMILY SSF47413 5 66 1.58E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS12780 6cf9d879991559643394a8ec04eb6487 98 Pfam PF01381 Helix-turn-helix 11 62 5.3E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS12780 6cf9d879991559643394a8ec04eb6487 98 Gene3D G3DSA:1.10.260.40 1 76 9.8E-15 T 28-03-2018 hmeg3_RS08405 a3d911470c2226b540dc69da82ac38a7 208 Gene3D G3DSA:1.20.58.220 96 207 3.0E-11 T 28-03-2018 hmeg3_RS08405 a3d911470c2226b540dc69da82ac38a7 208 Pfam PF01865 Protein of unknown function DUF47 8 206 1.4E-29 T 28-03-2018 IPR018445 Putative phosphate transport regulator hmeg3_RS02150 9c1e8fda52a6820095b323d912b3e982 494 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 321 4.6E-69 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS02150 9c1e8fda52a6820095b323d912b3e982 494 Pfam PF11604 Copper binding periplasmic protein CusF 427 490 2.2E-21 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF hmeg3_RS02150 9c1e8fda52a6820095b323d912b3e982 494 SUPERFAMILY SSF111369 129 328 4.18E-12 T 28-03-2018 hmeg3_RS02150 9c1e8fda52a6820095b323d912b3e982 494 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 215 396 1.4E-36 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS02150 9c1e8fda52a6820095b323d912b3e982 494 Gene3D G3DSA:2.40.50.100 124 248 3.1E-10 T 28-03-2018 hmeg3_RS19525 bb1fefe531b590a9e770eaf9b7706812 913 Gene3D G3DSA:3.40.50.300 288 620 5.1E-9 T 28-03-2018 hmeg3_RS19525 bb1fefe531b590a9e770eaf9b7706812 913 Gene3D G3DSA:3.90.320.10 621 839 1.1E-7 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 hmeg3_RS19525 bb1fefe531b590a9e770eaf9b7706812 913 SUPERFAMILY SSF52540 297 612 4.67E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19525 bb1fefe531b590a9e770eaf9b7706812 913 Pfam PF12705 PD-(D/E)XK nuclease superfamily 655 908 7.9E-32 T 28-03-2018 hmeg3_RS00145 0d785f07540bf1146f44696392452f4e 323 SUPERFAMILY SSF54593 1 279 6.78E-36 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS00145 0d785f07540bf1146f44696392452f4e 323 Gene3D G3DSA:3.10.180.10 1 141 1.0E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS00145 0d785f07540bf1146f44696392452f4e 323 Gene3D G3DSA:3.10.180.10 144 293 7.6E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS00145 0d785f07540bf1146f44696392452f4e 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 152 265 1.7E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS17715 b2dadfa6d13d89ead606a6a215a0c023 416 SUPERFAMILY SSF111369 83 332 2.62E-19 T 28-03-2018 hmeg3_RS17715 b2dadfa6d13d89ead606a6a215a0c023 416 Gene3D G3DSA:2.70.70.10 205 230 0.039 T 28-03-2018 hmeg3_RS17715 b2dadfa6d13d89ead606a6a215a0c023 416 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 397 2.5E-45 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS17715 b2dadfa6d13d89ead606a6a215a0c023 416 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 79 329 1.5E-22 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS17715 b2dadfa6d13d89ead606a6a215a0c023 416 Gene3D G3DSA:2.40.50.100 93 172 1.6E-12 T 28-03-2018 hmeg3_RS17715 b2dadfa6d13d89ead606a6a215a0c023 416 Gene3D G3DSA:2.40.50.100 231 388 0.0018 T 28-03-2018 hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 Gene3D G3DSA:3.40.190.10 89 174 4.3E-11 T 28-03-2018 hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 Gene3D G3DSA:3.40.190.10 175 261 1.9E-27 T 28-03-2018 hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 SUPERFAMILY SSF46785 4 87 5.25E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 Pfam PF03466 LysR substrate binding domain 88 290 1.9E-41 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 SUPERFAMILY SSF53850 90 293 5.43E-45 T 28-03-2018 hmeg3_RS00860 ffe97670ce8a5c732f0461b4452c40e1 299 Gene3D G3DSA:1.10.10.10 3 84 5.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24085 243d6f25b28909747c1744ee2eb582e6 119 Pfam PF11142 Protein of unknown function (DUF2917) 11 66 3.6E-17 T 28-03-2018 IPR021317 Protein of unknown function DUF2917 hmeg3_RS09215 9fd01b4d627e80f603149c869dd020c3 455 Gene3D G3DSA:3.40.190.10 47 133 4.0E-7 T 28-03-2018 hmeg3_RS09215 9fd01b4d627e80f603149c869dd020c3 455 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 22 283 2.0E-27 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family hmeg3_RS09215 9fd01b4d627e80f603149c869dd020c3 455 Pfam PF16868 NMT1-like family 54 285 1.5E-22 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family hmeg3_RS09215 9fd01b4d627e80f603149c869dd020c3 455 SUPERFAMILY SSF53850 48 298 1.97E-39 T 28-03-2018 hmeg3_RS09215 9fd01b4d627e80f603149c869dd020c3 455 Gene3D G3DSA:3.40.190.10 134 261 5.7E-12 T 28-03-2018 hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 Pfam PF00072 Response regulator receiver domain 4 116 4.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 4.9E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 SUPERFAMILY SSF46894 123 223 2.61E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 Gene3D G3DSA:1.10.10.10 124 225 2.6E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 Gene3D G3DSA:3.40.50.2300 1 123 4.1E-34 T 28-03-2018 hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 SMART SM00862 149 222 3.2E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 SUPERFAMILY SSF52172 1 126 8.82E-40 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06200 26463183ed254b070f8af2859bdb586b 225 SMART SM00448 2 115 2.0E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 SUPERFAMILY SSF52540 97 383 2.88E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 SMART SM00490 282 363 2.0E-33 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 Gene3D G3DSA:3.40.50.300 9 244 3.4E-55 T 28-03-2018 hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 Pfam PF00271 Helicase conserved C-terminal domain 257 363 2.7E-27 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 176 184 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 SMART SM00487 20 245 2.3E-53 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 Pfam PF00270 DEAD/DEAH box helicase 25 213 8.2E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS06980 d7843e2c74a7ab06b342bfad1dfa35e4 480 Gene3D G3DSA:3.40.50.300 245 476 2.6E-45 T 28-03-2018 hmeg3_RS02315 81e690ba16cb3841beb28870ef6266f9 281 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 13 276 2.0E-85 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 hmeg3_RS02315 81e690ba16cb3841beb28870ef6266f9 281 Gene3D G3DSA:1.10.3720.10 1 271 7.4E-35 T 28-03-2018 hmeg3_RS02315 81e690ba16cb3841beb28870ef6266f9 281 SUPERFAMILY SSF161098 22 267 2.62E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02315 81e690ba16cb3841beb28870ef6266f9 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 272 6.3E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 SUPERFAMILY SSF53795 140 305 1.28E-33 T 28-03-2018 hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 Pfam PF07475 HPr Serine kinase C-terminal domain 134 304 9.1E-64 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 6 312 36.621 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 Gene3D G3DSA:3.40.1390.20 6 137 5.0E-29 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 SUPERFAMILY SSF75138 11 136 1.44E-27 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 8 309 5.6E-100 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 Pfam PF02603 HPr Serine kinase N terminus 8 132 1.6E-20 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 hmeg3_RS04340 29905a4fae60ddcf1caf39e9bbca9f89 312 Gene3D G3DSA:3.40.50.300 140 312 5.4E-41 T 28-03-2018 hmeg3_RS15385 f337c44d23a2334e67d0774418fd5757 254 Gene3D G3DSA:3.60.10.10 1 254 9.2E-55 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS15385 f337c44d23a2334e67d0774418fd5757 254 SUPERFAMILY SSF56219 1 254 2.22E-80 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS15385 f337c44d23a2334e67d0774418fd5757 254 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 3.9E-78 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 hmeg3_RS15385 f337c44d23a2334e67d0774418fd5757 254 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 253 1.6E-82 T 28-03-2018 hmeg3_RS15385 f337c44d23a2334e67d0774418fd5757 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 1.6E-20 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS09555 94447f00605b700216fff979e33cd7bb 507 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 48 419 6.0E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS09555 94447f00605b700216fff979e33cd7bb 507 Gene3D G3DSA:3.90.76.10 15 155 6.8E-27 T 28-03-2018 hmeg3_RS09555 94447f00605b700216fff979e33cd7bb 507 PIRSF PIRSF002741 3 501 1.4E-82 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS09555 94447f00605b700216fff979e33cd7bb 507 SUPERFAMILY SSF53850 8 490 8.32E-109 T 28-03-2018 hmeg3_RS09555 94447f00605b700216fff979e33cd7bb 507 Gene3D G3DSA:3.40.190.10 156 277 9.9E-26 T 28-03-2018 hmeg3_RS09555 94447f00605b700216fff979e33cd7bb 507 Gene3D G3DSA:3.10.105.10 278 478 1.2E-39 T 28-03-2018 hmeg3_RS11775 1e17ef2cbf77b672500e03c51d641ea9 266 Gene3D G3DSA:2.40.50.100 167 240 2.9E-4 T 28-03-2018 hmeg3_RS11775 1e17ef2cbf77b672500e03c51d641ea9 266 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 260 3.4E-34 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS11775 1e17ef2cbf77b672500e03c51d641ea9 266 SUPERFAMILY SSF111369 46 254 3.14E-23 T 28-03-2018 hmeg3_RS11775 1e17ef2cbf77b672500e03c51d641ea9 266 Pfam PF13437 HlyD family secretion protein 152 239 2.7E-17 T 28-03-2018 hmeg3_RS11775 1e17ef2cbf77b672500e03c51d641ea9 266 Gene3D G3DSA:2.40.50.100 58 166 3.6E-13 T 28-03-2018 hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 SUPERFAMILY SSF53383 3 395 1.89E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 Hamap MF_01970 Kynureninase [kynU]. 3 394 34.588 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 PIRSF PIRSF038800 1 402 2.1E-147 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 Pfam PF00266 Aminotransferase class-V 31 334 1.7E-21 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 Gene3D G3DSA:3.90.1150.10 292 411 1.0E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 Gene3D G3DSA:3.40.640.10 41 291 8.4E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS19635 3052c4c781a5358974f90f3bf65f2816 411 TIGRFAM TIGR01814 kynureninase: kynureninase 9 395 2.8E-100 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 hmeg3_RS03470 7a2c426f5a0842a4a78ee8d0e06aca90 416 SUPERFAMILY SSF55205 1 415 1.96E-141 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 hmeg3_RS03470 7a2c426f5a0842a4a78ee8d0e06aca90 416 Gene3D G3DSA:3.65.10.10 21 219 7.8E-52 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 hmeg3_RS03470 7a2c426f5a0842a4a78ee8d0e06aca90 416 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 2.7E-177 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS03470 7a2c426f5a0842a4a78ee8d0e06aca90 416 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 44.399 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS03470 7a2c426f5a0842a4a78ee8d0e06aca90 416 Gene3D G3DSA:3.65.10.10 220 416 5.6E-45 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 hmeg3_RS03470 7a2c426f5a0842a4a78ee8d0e06aca90 416 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 2.0E-106 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 SMART SM00382 389 581 3.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 Gene3D G3DSA:3.40.50.300 352 605 1.8E-76 T 28-03-2018 hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 SUPERFAMILY SSF52540 356 599 3.26E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 SUPERFAMILY SSF90123 30 352 8.24E-66 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 Pfam PF00005 ABC transporter 382 529 7.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 Pfam PF00664 ABC transporter transmembrane region 42 316 7.2E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 Gene3D G3DSA:1.20.1560.10 21 351 5.2E-60 T 28-03-2018 hmeg3_RS04655 411a154c5ae9d222f15f59d5ec905661 620 ProSitePatterns PS00211 ABC transporters family signature. 501 515 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 Pfam PF00990 Diguanylate cyclase, GGDEF domain 360 519 1.6E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 354 522 1.2E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 Pfam PF02743 Cache domain 67 290 1.0E-18 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 Gene3D G3DSA:3.30.450.20 187 303 9.3E-13 T 28-03-2018 hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 SUPERFAMILY SSF55073 363 522 1.8E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 Gene3D G3DSA:3.30.70.270 351 527 1.6E-54 T 28-03-2018 hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 SMART SM00267 347 523 4.2E-65 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20750 5a354d3465f0c9a1359f17d12192bcd2 527 Gene3D G3DSA:3.30.450.20 55 186 3.6E-14 T 28-03-2018 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 112 122 1.1E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 171 182 1.1E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 199 211 1.1E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 68 79 1.1E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 311 328 1.1E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 SUPERFAMILY SSF56935 30 399 6.02E-73 T 28-03-2018 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00184 Neisseria sp. porin signature 344 368 3.4E-12 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00184 Neisseria sp. porin signature 70 95 3.4E-12 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 PRINTS PR00184 Neisseria sp. porin signature 170 187 3.4E-12 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 Gene3D G3DSA:2.40.160.10 31 399 4.5E-70 T 28-03-2018 hmeg3_RS10985 88b6049bcda54cb8e9de92e0712ad5b0 399 Pfam PF13609 Gram-negative porin 12 372 6.6E-49 T 28-03-2018 hmeg3_RS17740 c14ed12d05f608e4f662e39c34328a0b 174 Pfam PF02417 Chromate transporter 8 169 3.4E-35 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 hmeg3_RS17740 c14ed12d05f608e4f662e39c34328a0b 174 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 18 32 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 hmeg3_RS21495 f9985fe955a8fabbfd043a3895fccb20 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 259 4.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21495 f9985fe955a8fabbfd043a3895fccb20 271 Gene3D G3DSA:1.10.3720.10 2 259 5.4E-33 T 28-03-2018 hmeg3_RS21495 f9985fe955a8fabbfd043a3895fccb20 271 SUPERFAMILY SSF161098 6 271 1.31E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS18590 b2bd67c070589905f398580e49321488 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 444 2.1E-84 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS18590 b2bd67c070589905f398580e49321488 536 Gene3D G3DSA:3.90.76.10 60 160 1.8E-26 T 28-03-2018 hmeg3_RS18590 b2bd67c070589905f398580e49321488 536 SUPERFAMILY SSF53850 39 535 7.42E-128 T 28-03-2018 hmeg3_RS18590 b2bd67c070589905f398580e49321488 536 PIRSF PIRSF002741 1 536 6.6E-124 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS18590 b2bd67c070589905f398580e49321488 536 Gene3D G3DSA:3.10.105.10 304 503 8.0E-43 T 28-03-2018 hmeg3_RS18590 b2bd67c070589905f398580e49321488 536 Gene3D G3DSA:3.40.190.10 161 303 1.7E-42 T 28-03-2018 hmeg3_RS05770 061082c85003c535606b69599121fd30 383 Gene3D G3DSA:1.10.530.10 255 382 1.1E-32 T 28-03-2018 hmeg3_RS05770 061082c85003c535606b69599121fd30 383 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 78 376 6.5E-112 T 28-03-2018 IPR011757 Lytic transglycosylase MltB hmeg3_RS05770 061082c85003c535606b69599121fd30 383 SUPERFAMILY SSF53955 69 377 4.97E-81 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS05770 061082c85003c535606b69599121fd30 383 Gene3D G3DSA:1.10.8.350 139 249 3.8E-34 T 28-03-2018 hmeg3_RS05770 061082c85003c535606b69599121fd30 383 Gene3D G3DSA:1.10.8.350 68 138 2.1E-10 T 28-03-2018 hmeg3_RS05770 061082c85003c535606b69599121fd30 383 Pfam PF13406 Transglycosylase SLT domain 74 374 1.8E-94 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 hmeg3_RS06805 e30549a7295d251c0c8494f00a87da8f 242 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 145 159 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 hmeg3_RS06805 e30549a7295d251c0c8494f00a87da8f 242 Pfam PF08241 Methyltransferase domain 59 155 1.2E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS06805 e30549a7295d251c0c8494f00a87da8f 242 SUPERFAMILY SSF53335 27 199 1.82E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS06805 e30549a7295d251c0c8494f00a87da8f 242 Gene3D G3DSA:3.40.50.150 21 225 7.8E-33 T 28-03-2018 hmeg3_RS17640 f01d4e0a88f87d4d5e164cd4f26cf9fd 397 Gene3D G3DSA:3.40.710.10 27 395 2.0E-71 T 28-03-2018 hmeg3_RS17640 f01d4e0a88f87d4d5e164cd4f26cf9fd 397 Pfam PF00144 Beta-lactamase 35 377 4.6E-56 T 28-03-2018 IPR001466 Beta-lactamase-related hmeg3_RS17640 f01d4e0a88f87d4d5e164cd4f26cf9fd 397 SUPERFAMILY SSF56601 32 386 4.7E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS19375 1e03dc85118c12b43051f5f03ddf76ed 231 Pfam PF12697 Alpha/beta hydrolase family 48 224 5.9E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19375 1e03dc85118c12b43051f5f03ddf76ed 231 Gene3D G3DSA:3.40.50.1820 2 231 9.9E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS19375 1e03dc85118c12b43051f5f03ddf76ed 231 PRINTS PR00111 Alpha/beta hydrolase fold signature 74 87 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19375 1e03dc85118c12b43051f5f03ddf76ed 231 PRINTS PR00111 Alpha/beta hydrolase fold signature 176 190 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19375 1e03dc85118c12b43051f5f03ddf76ed 231 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 73 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS19375 1e03dc85118c12b43051f5f03ddf76ed 231 SUPERFAMILY SSF53474 6 230 3.81E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 Pfam PF12840 Helix-turn-helix domain 16 72 4.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 Gene3D G3DSA:1.10.10.10 61 100 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 SUPERFAMILY SSF46785 3 92 1.44E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 Gene3D G3DSA:1.10.10.10 23 60 8.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 SMART SM00418 16 93 1.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS23860 74129f7f6fb5f4bbca8b39de64c5f349 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 1.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS14600 a39d8d505cd9867eeb05f0547eea285b 411 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 409 3.6E-186 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase hmeg3_RS14600 a39d8d505cd9867eeb05f0547eea285b 411 Gene3D G3DSA:3.40.50.1820 55 411 1.2E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS14600 a39d8d505cd9867eeb05f0547eea285b 411 Pfam PF06850 PHB de-polymerase C-terminus 209 410 9.6E-97 T 28-03-2018 IPR009656 PHB de-polymerase, C-terminal hmeg3_RS14600 a39d8d505cd9867eeb05f0547eea285b 411 PIRSF PIRSF020818 1 411 6.7E-198 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase hmeg3_RS14600 a39d8d505cd9867eeb05f0547eea285b 411 SUPERFAMILY SSF53474 105 408 8.13E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 Gene3D G3DSA:3.90.1210.10 276 345 1.0E-23 T 28-03-2018 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 SUPERFAMILY SSF51569 2 300 1.05E-91 T 28-03-2018 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 SUPERFAMILY SSF51269 284 345 1.15E-17 T 28-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 13 340 1.2E-154 T 28-03-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 SMART SM00858 288 345 9.4E-7 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 Pfam PF03102 NeuB family 33 273 2.1E-89 T 28-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 Gene3D G3DSA:3.20.20.70 1 275 2.0E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS21285 cdb94daa5b904852f10e6977ced174ce 345 Pfam PF08666 SAF domain 289 343 2.3E-10 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Gene3D G3DSA:1.20.5.730 287 373 1.3E-4 T 28-03-2018 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1164 21.895 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1155 1.7E-63 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 SUPERFAMILY SSF75553 484 673 8.76E-15 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Gene3D G3DSA:3.40.50.300 2 220 3.6E-37 T 28-03-2018 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 PIRSF PIRSF005719 1 1170 7.0E-252 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1162 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 SUPERFAMILY SSF52540 1061 1148 6.04E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 SUPERFAMILY SSF52540 2 217 6.04E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Pfam PF06470 SMC proteins Flexible Hinge Domain 521 622 9.6E-8 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Gene3D G3DSA:1.10.287.620 433 510 0.082 T 28-03-2018 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 SMART SM00968 518 626 5.4E-10 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Gene3D G3DSA:1.20.120.330 654 782 0.2 T 28-03-2018 hmeg3_RS09875 74db36d6eaa17ba52ccba09e15c36034 1175 Gene3D G3DSA:3.40.50.300 904 1167 8.1E-31 T 28-03-2018 hmeg3_RS14850 0cdd4b0e45de69aca91e2b01b7bbe893 82 Pfam PF01381 Helix-turn-helix 18 70 4.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS14850 0cdd4b0e45de69aca91e2b01b7bbe893 82 SUPERFAMILY SSF47413 11 79 1.01E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS14850 0cdd4b0e45de69aca91e2b01b7bbe893 82 SMART SM00530 17 72 3.8E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS14850 0cdd4b0e45de69aca91e2b01b7bbe893 82 Gene3D G3DSA:1.10.260.40 13 78 1.3E-16 T 28-03-2018 hmeg3_RS19415 1cf2033c75eff6a08d95fe6eca913816 414 Pfam PF00263 Bacterial type II and III secretion system protein 261 389 1.3E-18 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 hmeg3_RS19415 1cf2033c75eff6a08d95fe6eca913816 414 PRINTS PR01032 Gene IV protein signature 348 376 5.6E-5 T 28-03-2018 hmeg3_RS19415 1cf2033c75eff6a08d95fe6eca913816 414 PRINTS PR01032 Gene IV protein signature 279 302 5.6E-5 T 28-03-2018 hmeg3_RS21535 4c80a8e5c491c51b5a6bc3f62f47a676 210 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 210 22.664 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 hmeg3_RS21535 4c80a8e5c491c51b5a6bc3f62f47a676 210 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 204 2.5E-52 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 hmeg3_RS21535 4c80a8e5c491c51b5a6bc3f62f47a676 210 Pfam PF02581 Thiamine monophosphate synthase 12 192 1.1E-51 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 hmeg3_RS21535 4c80a8e5c491c51b5a6bc3f62f47a676 210 SUPERFAMILY SSF51391 7 208 3.66E-53 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 hmeg3_RS21535 4c80a8e5c491c51b5a6bc3f62f47a676 210 Gene3D G3DSA:3.20.20.70 1 209 2.9E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS15640 5631458d8be6baebbe326366b414b69e 256 Gene3D G3DSA:3.40.190.10 156 256 3.4E-15 T 28-03-2018 hmeg3_RS15640 5631458d8be6baebbe326366b414b69e 256 SMART SM00062 32 256 3.9E-44 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS15640 5631458d8be6baebbe326366b414b69e 256 SUPERFAMILY SSF53850 8 254 3.44E-53 T 28-03-2018 hmeg3_RS15640 5631458d8be6baebbe326366b414b69e 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 253 2.5E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS15640 5631458d8be6baebbe326366b414b69e 256 Gene3D G3DSA:3.40.190.10 27 155 5.9E-26 T 28-03-2018 hmeg3_RS04270 1eb72d5ed7b5405ea7db811cdad00e96 321 Pfam PF03741 Integral membrane protein TerC family 84 285 3.1E-58 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 hmeg3_RS04270 1eb72d5ed7b5405ea7db811cdad00e96 321 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 10 316 1.6E-126 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 hmeg3_RS17865 a966022ca6444845852dd6ea6ac3e7af 284 Pfam PF01380 SIS domain 124 251 1.2E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS17865 a966022ca6444845852dd6ea6ac3e7af 284 SUPERFAMILY SSF53697 92 266 8.9E-34 T 28-03-2018 hmeg3_RS17865 a966022ca6444845852dd6ea6ac3e7af 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 74 9.7E-22 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 hmeg3_RS17865 a966022ca6444845852dd6ea6ac3e7af 284 Gene3D G3DSA:1.10.10.10 1 97 1.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17865 a966022ca6444845852dd6ea6ac3e7af 284 SUPERFAMILY SSF46689 3 73 1.79E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS17865 a966022ca6444845852dd6ea6ac3e7af 284 Gene3D G3DSA:3.40.50.10490 98 277 1.2E-30 T 28-03-2018 hmeg3_RS18075 a68a80f179cbb58fee8b48d76a16e32b 160 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 5.3E-59 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 hmeg3_RS18075 a68a80f179cbb58fee8b48d76a16e32b 160 Pfam PF03477 ATP cone domain 50 136 2.2E-12 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 hmeg3_RS18075 a68a80f179cbb58fee8b48d76a16e32b 160 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.497 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 hmeg3_RS04635 bd83d57c61ccd2753b264cba6dc3cea3 207 Pfam PF01081 KDPG and KHG aldolase 3 185 6.6E-31 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 hmeg3_RS04635 bd83d57c61ccd2753b264cba6dc3cea3 207 SUPERFAMILY SSF51569 4 203 3.85E-56 T 28-03-2018 hmeg3_RS04635 bd83d57c61ccd2753b264cba6dc3cea3 207 Gene3D G3DSA:3.20.20.70 1 207 3.0E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS00530 af2c73f99c9bc2c7da0a9275148aa740 392 SUPERFAMILY SSF103473 25 387 2.62E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00530 af2c73f99c9bc2c7da0a9275148aa740 392 Gene3D G3DSA:1.20.1250.20 17 210 1.7E-16 T 28-03-2018 hmeg3_RS00530 af2c73f99c9bc2c7da0a9275148aa740 392 Gene3D G3DSA:1.20.1250.20 211 389 5.6E-16 T 28-03-2018 hmeg3_RS00530 af2c73f99c9bc2c7da0a9275148aa740 392 Pfam PF07690 Major Facilitator Superfamily 33 214 8.0E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS21435 cc62814ff819301e22bb53f6211799cf 294 Gene3D G3DSA:3.40.50.1820 52 291 2.3E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21435 cc62814ff819301e22bb53f6211799cf 294 Pfam PF01738 Dienelactone hydrolase family 70 291 5.5E-62 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS21435 cc62814ff819301e22bb53f6211799cf 294 SUPERFAMILY SSF53474 59 291 4.13E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05790 ea4c299d8a90a703d1b59780cde1f72d 317 Gene3D G3DSA:1.10.1580.10 177 277 3.0E-20 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain hmeg3_RS05790 ea4c299d8a90a703d1b59780cde1f72d 317 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 274 8.3E-95 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis hmeg3_RS05790 ea4c299d8a90a703d1b59780cde1f72d 317 Gene3D G3DSA:1.20.120.430 10 176 5.4E-27 T 28-03-2018 hmeg3_RS05790 ea4c299d8a90a703d1b59780cde1f72d 317 SUPERFAMILY SSF52540 9 185 4.65E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05790 ea4c299d8a90a703d1b59780cde1f72d 317 Pfam PF01926 50S ribosome-binding GTPase 119 178 6.8E-15 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS05790 ea4c299d8a90a703d1b59780cde1f72d 317 PIRSF PIRSF006230 1 279 1.8E-90 T 28-03-2018 IPR016478 GTPase, MTG1 hmeg3_RS14945 d7eb84c8acc655d5e99347dfbf098e03 205 SUPERFAMILY SSF48498 84 195 1.29E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS14945 d7eb84c8acc655d5e99347dfbf098e03 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS14945 d7eb84c8acc655d5e99347dfbf098e03 205 Gene3D G3DSA:1.10.357.10 65 198 9.1E-26 T 28-03-2018 hmeg3_RS14945 d7eb84c8acc655d5e99347dfbf098e03 205 Gene3D G3DSA:1.10.10.60 4 64 1.2E-11 T 28-03-2018 hmeg3_RS14945 d7eb84c8acc655d5e99347dfbf098e03 205 SUPERFAMILY SSF46689 6 77 6.67E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 Gene3D G3DSA:1.10.1050.10 1 102 6.0E-41 T 28-03-2018 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 4.4E-31 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.87 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 6.0E-79 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 Gene3D G3DSA:1.10.1050.10 146 207 6.3E-14 T 28-03-2018 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 SMART SM01390 3 96 7.5E-47 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 SMART SM00363 97 161 8.3E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 Gene3D G3DSA:3.10.290.10 103 145 5.9E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 Pfam PF01479 S4 domain 98 144 2.3E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS22735 c6952393853a7cd909f84c54ba58fd3f 207 SUPERFAMILY SSF55174 3 207 2.49E-66 T 28-03-2018 hmeg3_RS08175 d258b6a8be145e4274e6c8149186ea24 159 SUPERFAMILY SSF140566 12 132 3.01E-22 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 hmeg3_RS08175 d258b6a8be145e4274e6c8149186ea24 159 Gene3D G3DSA:1.20.58.300 10 132 1.1E-19 T 28-03-2018 hmeg3_RS08175 d258b6a8be145e4274e6c8149186ea24 159 Pfam PF05130 FlgN protein 7 147 2.0E-28 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 Pfam PF00411 Ribosomal protein S11 24 133 4.3E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 134 33.24 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 6.8E-57 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 Gene3D G3DSA:3.30.420.80 10 134 1.6E-46 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 PIRSF PIRSF002131 3 134 9.2E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 SUPERFAMILY SSF53137 18 134 7.19E-48 T 28-03-2018 hmeg3_RS22740 e064d3b7fe94b4e5032286b2a1986c69 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 32 40 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 Gene3D G3DSA:3.40.50.40 242 354 4.9E-29 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 Gene3D G3DSA:3.40.50.1170 25 238 1.9E-57 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 PIRSF PIRSF001220 24 354 2.0E-92 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 SUPERFAMILY SSF53774 27 354 3.93E-103 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 10 355 2.0E-142 T 28-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 SMART SM00870 29 349 3.8E-144 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 Pfam PF00710 Asparaginase, N-terminal 29 222 2.7E-60 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 PIRSF PIRSF500176 26 355 1.1E-80 T 28-03-2018 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 111 121 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 PRINTS PR00139 Asparaginase/glutaminase family signature 289 307 3.4E-23 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 PRINTS PR00139 Asparaginase/glutaminase family signature 110 128 3.4E-23 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS04235 499c5afbec40490f006aeb808677f7e6 355 PRINTS PR00139 Asparaginase/glutaminase family signature 30 41 3.4E-23 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 Gene3D G3DSA:3.20.20.210 2 399 8.7E-152 T 28-03-2018 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 SUPERFAMILY SSF51726 406 766 1.44E-116 T 28-03-2018 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 Gene3D G3DSA:3.20.20.210 400 769 7.4E-127 T 28-03-2018 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 SUPERFAMILY SSF51726 4 404 1.96E-110 T 28-03-2018 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 442 763 3.8E-154 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 767 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 PIRSF PIRSF000382 1 770 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 768 37.502 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS23910 a1e3071c43a382c94102c473e72ff4cc 770 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 324 1.1E-116 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Pfam PF14559 Tetratricopeptide repeat 244 296 2.4E-6 T 28-03-2018 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SUPERFAMILY SSF48452 412 577 6.5E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SUPERFAMILY SSF48452 170 334 6.5E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Gene3D G3DSA:1.25.40.10 524 589 9.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Gene3D G3DSA:1.25.40.10 242 348 2.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Gene3D G3DSA:1.25.40.10 384 474 1.5E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Pfam PF04733 Coatomer epsilon subunit 327 474 3.8E-6 T 28-03-2018 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Gene3D G3DSA:1.25.40.10 349 383 0.063 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Gene3D G3DSA:1.25.40.10 475 523 1.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Gene3D G3DSA:1.25.40.10 40 240 1.1E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 Pfam PF13432 Tetratricopeptide repeat 515 574 0.006 T 28-03-2018 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SMART SM00028 546 575 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SMART SM00028 509 542 48.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SMART SM00028 406 439 170.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SMART SM00028 440 473 28.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SMART SM00028 474 508 500.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS04320 6fee1028cb42fa1d52a5d714c731d871 589 SMART SM00028 196 229 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS24415 66775a37048a76727ddfcbb0712c8756 196 Pfam PF00583 Acetyltransferase (GNAT) family 64 166 2.2E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS24415 66775a37048a76727ddfcbb0712c8756 196 Gene3D G3DSA:3.40.630.30 7 192 7.7E-17 T 28-03-2018 hmeg3_RS24415 66775a37048a76727ddfcbb0712c8756 196 SUPERFAMILY SSF55729 13 166 2.27E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 Gene3D G3DSA:1.10.10.10 135 241 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 8.9E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 Pfam PF00072 Response regulator receiver domain 7 118 1.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 SMART SM00862 159 235 5.0E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 SUPERFAMILY SSF52172 5 137 1.2E-41 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 Gene3D G3DSA:3.40.50.2300 5 134 1.4E-38 T 28-03-2018 hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 SUPERFAMILY SSF46894 140 236 2.41E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06300 a2aee7ccfc246614c85768dac54a10a3 246 SMART SM00448 5 117 2.7E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS24535 c0a4d08674b166a23724d30befc47054 105 SUPERFAMILY SSF54292 21 99 1.01E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS24535 c0a4d08674b166a23724d30befc47054 105 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 19 96 4.2E-23 T 28-03-2018 hmeg3_RS24535 c0a4d08674b166a23724d30befc47054 105 Gene3D G3DSA:3.10.20.30 18 96 1.7E-7 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 Gene3D G3DSA:2.40.10.10 38 192 2.8E-38 T 28-03-2018 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 Pfam PF13365 Trypsin-like peptidase domain 122 253 1.1E-32 T 28-03-2018 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 Gene3D G3DSA:2.30.42.10 293 396 2.4E-24 T 28-03-2018 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 Gene3D G3DSA:2.30.42.10 404 498 3.5E-12 T 28-03-2018 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 Pfam PF13180 PDZ domain 292 383 3.2E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 SUPERFAMILY SSF50156 250 374 2.1E-23 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 SMART SM00228 406 484 0.0096 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 SMART SM00228 292 374 1.7E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 40 489 3.7E-151 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 SUPERFAMILY SSF50494 38 283 2.35E-64 T 28-03-2018 IPR009003 Peptidase S1, PA clan hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 SUPERFAMILY SSF50156 407 494 8.68E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 Gene3D G3DSA:2.40.10.10 193 292 3.1E-38 T 28-03-2018 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 PRINTS PR00834 HtrA/DegQ protease family signature 152 172 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 PRINTS PR00834 HtrA/DegQ protease family signature 246 263 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 PRINTS PR00834 HtrA/DegQ protease family signature 224 241 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 PRINTS PR00834 HtrA/DegQ protease family signature 131 143 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 PRINTS PR00834 HtrA/DegQ protease family signature 192 216 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS16700 fcf4e866b6aeba4d093c4020b5aadc76 498 PRINTS PR00834 HtrA/DegQ protease family signature 332 344 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 hmeg3_RS08825 8c6e05b8f56e0b9932b2133c48c190a1 308 Gene3D G3DSA:3.40.50.150 88 307 2.4E-31 T 28-03-2018 hmeg3_RS08825 8c6e05b8f56e0b9932b2133c48c190a1 308 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 91 307 32.885 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 hmeg3_RS08825 8c6e05b8f56e0b9932b2133c48c190a1 308 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 230 245 - T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 hmeg3_RS08825 8c6e05b8f56e0b9932b2133c48c190a1 308 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 103 303 2.3E-55 T 28-03-2018 hmeg3_RS08825 8c6e05b8f56e0b9932b2133c48c190a1 308 SUPERFAMILY SSF53335 111 305 4.87E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS08825 8c6e05b8f56e0b9932b2133c48c190a1 308 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 101 303 2.8E-56 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 Gene3D G3DSA:1.10.287.950 321 514 1.1E-46 T 28-03-2018 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 Gene3D G3DSA:1.10.287.950 65 320 1.6E-18 T 28-03-2018 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 169 5.0E-15 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 SMART SM00304 211 263 1.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 Pfam PF00672 HAMP domain 211 259 4.5E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 478 1.0E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 SMART SM00283 264 511 1.7E-80 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11900 cce7b7c621a1841ea530c1c89c70acb4 514 SUPERFAMILY SSF58104 231 512 1.83E-73 T 28-03-2018 hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 Gene3D G3DSA:3.30.565.10 310 463 2.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 457 3.6E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 SUPERFAMILY SSF55874 314 456 1.96E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 SUPERFAMILY SSF47384 229 301 2.55E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 Gene3D G3DSA:1.10.287.130 224 303 3.9E-5 T 28-03-2018 hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 5.6E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 5.6E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 5.6E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11270 c3595a19aa20f5ead10e2a25c65784a2 490 SMART SM00387 349 458 9.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 SUPERFAMILY SSF46785 5 72 4.17E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 SUPERFAMILY SSF53383 85 441 4.79E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 Gene3D G3DSA:1.10.10.10 1 73 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 Gene3D G3DSA:3.40.640.10 113 325 5.5E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 Pfam PF00155 Aminotransferase class I and II 88 433 1.6E-37 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 Gene3D G3DSA:3.90.1150.10 326 443 3.7E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 SMART SM00345 9 68 9.6E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23940 a4a02fa107faa75d10f1534f67722a5a 444 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 1.6E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 409 1.8E-94 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 348 426 5.9E-19 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 Pfam PF00460 Flagella basal body rod protein 3 33 5.4E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 SUPERFAMILY SSF117143 79 388 4.58E-70 T 28-03-2018 hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 Pfam PF07559 Flagellar basal body protein FlaE 181 307 4.5E-21 T 28-03-2018 IPR011491 Flagellar hook protein FlgE hmeg3_RS08205 cabcb4ad764447729717dde405251f91 427 Gene3D G3DSA:2.60.98.20 151 308 3.6E-26 T 28-03-2018 IPR011491 Flagellar hook protein FlgE hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 SUPERFAMILY SSF53697 437 600 1.17E-29 T 28-03-2018 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 SUPERFAMILY SSF53067 25 336 1.36E-58 T 28-03-2018 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 TIGRFAM TIGR00749 glk: glucokinase 23 326 4.9E-100 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Hamap MF_00524 Glucokinase [glk]. 21 334 33.268 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Pfam PF01418 Helix-turn-helix domain, rpiR family 343 412 1.3E-18 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Pfam PF02685 Glucokinase 23 332 1.0E-110 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Gene3D G3DSA:3.40.50.10490 420 623 5.7E-25 T 28-03-2018 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Gene3D G3DSA:3.40.367.20 127 317 2.4E-31 T 28-03-2018 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Gene3D G3DSA:3.30.420.40 9 126 2.8E-14 T 28-03-2018 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 SUPERFAMILY SSF46689 342 415 2.87E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Gene3D G3DSA:1.10.10.10 338 417 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 Pfam PF01380 SIS domain 465 591 3.2E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS19115 4fa8a883ddaebeec3d33ddd10b256a3c 653 ProSitePatterns PS00356 LacI-type HTH domain signature. 377 395 - T 28-03-2018 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 365 529 3.3E-40 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 SUPERFAMILY SSF55073 374 531 2.79E-47 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 Pfam PF00672 HAMP domain 314 358 8.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 Gene3D G3DSA:3.30.70.270 352 532 5.9E-59 T 28-03-2018 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 SMART SM00267 358 531 5.5E-60 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 Pfam PF02743 Cache domain 41 272 6.4E-17 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 Gene3D G3DSA:3.30.450.20 168 288 1.3E-12 T 28-03-2018 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 SMART SM00304 310 363 0.001 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 Gene3D G3DSA:3.30.450.20 38 167 6.5E-12 T 28-03-2018 hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 Pfam PF00990 Diguanylate cyclase, GGDEF domain 369 526 2.6E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09210 5579fbb9f4ab359cea72df712937ad16 538 SUPERFAMILY SSF158472 311 359 7.19E-7 T 28-03-2018 hmeg3_RS00490 a272db0bcf92878d392ea5ddc5b671c7 197 Gene3D G3DSA:3.90.420.10 20 182 1.5E-18 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS00490 a272db0bcf92878d392ea5ddc5b671c7 197 SUPERFAMILY SSF56524 70 166 1.43E-10 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 624 682 9.0E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 185 279 2.0E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Gene3D G3DSA:2.40.30.10 338 441 4.9E-22 T 28-03-2018 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Gene3D G3DSA:3.10.20.30 582 692 4.2E-18 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Pfam PF00970 Oxidoreductase FAD-binding domain 353 442 4.9E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 SUPERFAMILY SSF54292 575 687 9.04E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Gene3D G3DSA:3.40.50.80 443 581 7.0E-26 T 28-03-2018 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 SUPERFAMILY SSF52343 449 586 5.76E-33 T 28-03-2018 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 SUPERFAMILY SSF50475 186 301 5.89E-10 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 PRINTS PR00410 Phenol hydroxylase reductase family signature 396 403 1.5E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 PRINTS PR00410 Phenol hydroxylase reductase family signature 437 446 1.5E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 PRINTS PR00410 Phenol hydroxylase reductase family signature 550 558 1.5E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 PRINTS PR00410 Phenol hydroxylase reductase family signature 453 472 1.5E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Gene3D G3DSA:2.30.110.10 173 321 2.5E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Pfam PF00175 Oxidoreductase NAD-binding domain 454 562 7.0E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 Gene3D G3DSA:2.30.110.10 45 163 0.016 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 643 651 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS00505 22fe0c8ce7c9f75bbee6dd4e3498aeac 693 SUPERFAMILY SSF63380 343 442 4.3E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 SUPERFAMILY SSF52172 13 144 3.27E-24 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 Gene3D G3DSA:1.10.10.10 145 230 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 SUPERFAMILY SSF46894 166 233 7.48E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 SMART SM00421 170 227 4.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 SMART SM00448 13 126 2.7E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 8.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 8.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 8.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 Gene3D G3DSA:3.40.50.2300 12 144 7.2E-26 T 28-03-2018 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 187 214 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 225 2.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS23455 14c4a8877a965689050e2e15fa9dab70 235 Pfam PF00072 Response regulator receiver domain 15 126 1.2E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10430 f42247160243588adbb6aba3ff6ddf37 65 Pfam PF07866 Protein of unknown function (DUF1653) 2 59 1.0E-17 T 28-03-2018 IPR023387 DUF1653-like domain hmeg3_RS10430 f42247160243588adbb6aba3ff6ddf37 65 Gene3D G3DSA:2.30.30.320 1 65 4.2E-16 T 28-03-2018 IPR023387 DUF1653-like domain hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 SUPERFAMILY SSF55785 25 139 2.97E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 SUPERFAMILY SSF55073 153 312 7.53E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 SMART SM00267 137 310 1.2E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 Gene3D G3DSA:3.30.450.20 10 144 2.8E-11 T 28-03-2018 hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 Pfam PF00990 Diguanylate cyclase, GGDEF domain 148 306 4.6E-42 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 308 1.3E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 Gene3D G3DSA:3.30.70.270 145 315 2.5E-51 T 28-03-2018 hmeg3_RS01640 fb64a993cf04fd6ce61ded1b3f0f010f 319 Pfam PF12860 PAS fold 23 134 3.9E-12 T 28-03-2018 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 SUPERFAMILY SSF49472 1 117 1.44E-39 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 PRINTS PR00189 Transthyretin signature 95 117 1.8E-5 T 28-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 PRINTS PR00189 Transthyretin signature 3 23 1.8E-5 T 28-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 Gene3D G3DSA:2.60.40.180 1 117 5.7E-37 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 117 5.5E-38 T 28-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 Pfam PF00576 HIUase/Transthyretin family 4 116 9.3E-34 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 hmeg3_RS07265 0ffde2e7b423bcf022910587fc8d9388 117 ProSitePatterns PS00769 Transthyretin signature 2. 100 112 - T 28-03-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 hmeg3_RS16280 7b3513ef7b8abba29f5d414ebb2ca0d5 351 SUPERFAMILY SSF56266 11 338 1.65E-101 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS16280 7b3513ef7b8abba29f5d414ebb2ca0d5 351 Pfam PF03576 Peptidase family S58 18 334 9.1E-112 T 28-03-2018 IPR005321 Peptidase S58, DmpA hmeg3_RS16280 7b3513ef7b8abba29f5d414ebb2ca0d5 351 Gene3D G3DSA:3.60.70.12 3 349 1.4E-107 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS24165 60368a789f347fca8ddcd26d632b5175 210 Pfam PF01810 LysE type translocator 22 208 3.2E-39 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS24165 60368a789f347fca8ddcd26d632b5175 210 PIRSF PIRSF006324 7 210 9.2E-53 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 SUPERFAMILY SSF51905 43 85 1.51E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 SUPERFAMILY SSF51905 121 407 1.51E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 191 2.2E-10 T 28-03-2018 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 65 2.2E-10 T 28-03-2018 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 224 249 2.2E-10 T 28-03-2018 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 Gene3D G3DSA:3.50.50.60 218 442 5.8E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 1.8E-6 T 28-03-2018 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 1.8E-6 T 28-03-2018 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 224 242 1.8E-6 T 28-03-2018 hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 125 263 4.8E-12 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase hmeg3_RS11080 1067cec6d71989ae24b9d13ee1d0fc7a 487 Gene3D G3DSA:3.50.50.60 39 217 1.9E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23895 813abba94a4b265c56f17a5c260598e0 165 SMART SM00972 104 162 3.9E-22 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS23895 813abba94a4b265c56f17a5c260598e0 165 Pfam PF05229 Spore Coat Protein U domain 31 162 3.9E-35 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS19215 c383b0844863511d931cbe0132246a30 256 Gene3D G3DSA:3.40.50.300 1 254 7.0E-57 T 28-03-2018 hmeg3_RS19215 c383b0844863511d931cbe0132246a30 256 Pfam PF00005 ABC transporter 20 173 2.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19215 c383b0844863511d931cbe0132246a30 256 SMART SM00382 28 221 8.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19215 c383b0844863511d931cbe0132246a30 256 SUPERFAMILY SSF52540 3 244 9.1E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19215 c383b0844863511d931cbe0132246a30 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 1.8E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 Pfam PF03466 LysR substrate binding domain 93 295 8.1E-21 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 6.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 Gene3D G3DSA:3.40.190.10 183 269 7.9E-15 T 28-03-2018 hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 SUPERFAMILY SSF46785 2 79 1.15E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 Gene3D G3DSA:3.40.190.10 96 182 1.6E-13 T 28-03-2018 hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 Gene3D G3DSA:1.10.10.10 1 82 1.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01200 aa803d8713e7be46b711c5cc48ab678d 300 SUPERFAMILY SSF53850 88 296 2.29E-43 T 28-03-2018 hmeg3_RS09425 158f35146c93d0114d726ef8ce1eb6d7 335 Gene3D G3DSA:3.40.190.10 130 332 9.8E-25 T 28-03-2018 hmeg3_RS09425 158f35146c93d0114d726ef8ce1eb6d7 335 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 43 244 9.2E-14 T 28-03-2018 hmeg3_RS09425 158f35146c93d0114d726ef8ce1eb6d7 335 SUPERFAMILY SSF53850 27 247 2.27E-39 T 28-03-2018 hmeg3_RS09425 158f35146c93d0114d726ef8ce1eb6d7 335 SMART SM00062 29 267 2.2E-6 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09425 158f35146c93d0114d726ef8ce1eb6d7 335 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 30 329 1.8E-107 T 28-03-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 hmeg3_RS09425 158f35146c93d0114d726ef8ce1eb6d7 335 Gene3D G3DSA:3.40.190.10 25 129 1.3E-9 T 28-03-2018 hmeg3_RS14615 c10921774a2f7e8fa2c68618169147eb 173 Pfam PF16970 Type-1 fimbrial protein, A 51 173 4.7E-18 T 28-03-2018 hmeg3_RS14615 c10921774a2f7e8fa2c68618169147eb 173 Gene3D G3DSA:2.60.40.1090 25 172 3.5E-32 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS14615 c10921774a2f7e8fa2c68618169147eb 173 SUPERFAMILY SSF49401 26 172 8.95E-29 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS15660 c10921774a2f7e8fa2c68618169147eb 173 Pfam PF16970 Type-1 fimbrial protein, A 51 173 4.7E-18 T 28-03-2018 hmeg3_RS15660 c10921774a2f7e8fa2c68618169147eb 173 Gene3D G3DSA:2.60.40.1090 25 172 3.5E-32 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS15660 c10921774a2f7e8fa2c68618169147eb 173 SUPERFAMILY SSF49401 26 172 8.95E-29 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 158 8.5E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 SUPERFAMILY SSF46767 77 159 1.18E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 158 42.294 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 75 2.7E-10 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 157 1.3E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 Gene3D G3DSA:1.10.10.10 74 160 3.2E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 SUPERFAMILY SSF53155 3 83 8.63E-19 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 hmeg3_RS05820 1f4775cb3f1bbc962ca85dc89b0ffc2b 189 Gene3D G3DSA:3.30.160.70 1 73 1.0E-19 T 28-03-2018 hmeg3_RS06750 dfc217988d5d082c4b15b19f9e1b21cd 281 Pfam PF00005 ABC transporter 43 181 3.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06750 dfc217988d5d082c4b15b19f9e1b21cd 281 Gene3D G3DSA:3.40.50.300 24 274 7.1E-57 T 28-03-2018 hmeg3_RS06750 dfc217988d5d082c4b15b19f9e1b21cd 281 SUPERFAMILY SSF52540 27 249 6.14E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06750 dfc217988d5d082c4b15b19f9e1b21cd 281 SMART SM00382 51 232 2.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 9.7E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 9.7E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 Pfam PF09278 MerR, DNA binding 47 111 1.6E-20 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 Pfam PF00376 MerR family regulatory protein 5 42 1.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 SUPERFAMILY SSF46955 4 129 1.79E-35 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 SMART SM00422 4 73 8.4E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 Gene3D G3DSA:1.10.1660.10 60 141 2.8E-22 T 28-03-2018 hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 Gene3D G3DSA:1.10.1660.10 1 59 2.1E-21 T 28-03-2018 hmeg3_RS14685 22a8af00fd91dac66f6bc79070ae75b1 150 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 4 130 2.2E-57 T 28-03-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 hmeg3_RS13750 306b2f8dc81a706c2ae2e072b0f22701 359 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 71 86 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13750 306b2f8dc81a706c2ae2e072b0f22701 359 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 237 250 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13750 306b2f8dc81a706c2ae2e072b0f22701 359 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 25 354 25.023 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13750 306b2f8dc81a706c2ae2e072b0f22701 359 Pfam PF00146 NADH dehydrogenase 32 347 1.8E-126 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS15540 7630e0c1ce7af50905aa9352ada4f25d 134 Gene3D G3DSA:3.90.1010.10 1 134 5.5E-52 T 28-03-2018 hmeg3_RS15540 7630e0c1ce7af50905aa9352ada4f25d 134 Pfam PF01592 NifU-like N terminal domain 3 125 1.1E-55 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 hmeg3_RS15540 7630e0c1ce7af50905aa9352ada4f25d 134 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 2.1E-68 T 28-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 hmeg3_RS15540 7630e0c1ce7af50905aa9352ada4f25d 134 SUPERFAMILY SSF82649 2 125 1.05E-48 T 28-03-2018 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 SMART SM00245 174 383 4.7E-55 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 Pfam PF03572 Peptidase family S41 200 381 9.4E-49 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 Gene3D G3DSA:3.90.226.10 175 458 4.0E-62 T 28-03-2018 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 Gene3D G3DSA:3.30.750.44 39 108 1.1E-15 T 28-03-2018 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 SUPERFAMILY SSF52096 193 392 6.46E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 SUPERFAMILY SSF52096 37 119 6.46E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 Pfam PF13180 PDZ domain 102 180 3.3E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 SUPERFAMILY SSF50156 92 184 4.87E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 SMART SM00228 101 172 7.2E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 53 385 3.3E-94 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 hmeg3_RS22570 6f3269d6107a3a80de65b5ed71cfa886 506 Gene3D G3DSA:2.30.42.10 109 174 2.3E-16 T 28-03-2018 hmeg3_RS06440 e25851af7d5523e8e08ed893c3b81823 404 Gene3D G3DSA:3.40.390.10 142 362 1.1E-14 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 hmeg3_RS06440 e25851af7d5523e8e08ed893c3b81823 404 PIRSF PIRSF012641 1 404 2.9E-135 T 28-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase hmeg3_RS06440 e25851af7d5523e8e08ed893c3b81823 404 Pfam PF10005 zinc-ribbon domain 3 44 9.1E-11 T 28-03-2018 IPR011201 Zinc-ribbon domain, bacteria hmeg3_RS06440 e25851af7d5523e8e08ed893c3b81823 404 Pfam PF10005 zinc-ribbon domain 92 144 1.5E-11 T 28-03-2018 IPR011201 Zinc-ribbon domain, bacteria hmeg3_RS06440 e25851af7d5523e8e08ed893c3b81823 404 Pfam PF15887 Putative zinc-binding metallo-peptidase 151 394 5.4E-105 T 28-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase hmeg3_RS21505 c259343d9e570c9f61d5db4a8b94cc63 448 SUPERFAMILY SSF53850 32 442 1.67E-81 T 28-03-2018 hmeg3_RS21505 c259343d9e570c9f61d5db4a8b94cc63 448 Pfam PF01547 Bacterial extracellular solute-binding protein 50 337 4.8E-50 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 hmeg3_RS21505 c259343d9e570c9f61d5db4a8b94cc63 448 Gene3D G3DSA:3.40.190.10 35 158 5.0E-24 T 28-03-2018 hmeg3_RS21505 c259343d9e570c9f61d5db4a8b94cc63 448 Gene3D G3DSA:3.40.190.10 159 444 1.7E-48 T 28-03-2018 hmeg3_RS00830 654f70900ad99c7872a2e91c160c0d5d 497 Pfam PF00171 Aldehyde dehydrogenase family 15 477 4.9E-145 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00830 654f70900ad99c7872a2e91c160c0d5d 497 Gene3D G3DSA:3.40.605.10 1 262 5.8E-90 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00830 654f70900ad99c7872a2e91c160c0d5d 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00830 654f70900ad99c7872a2e91c160c0d5d 497 SUPERFAMILY SSF53720 3 483 1.96E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS00830 654f70900ad99c7872a2e91c160c0d5d 497 Gene3D G3DSA:3.40.309.10 263 460 2.7E-65 T 28-03-2018 hmeg3_RS00830 654f70900ad99c7872a2e91c160c0d5d 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 481 9.8E-218 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 Gene3D G3DSA:1.10.287.130 111 182 4.2E-9 T 28-03-2018 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 341 4.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 SUPERFAMILY SSF55874 192 341 1.44E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 SMART SM00387 236 344 6.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 1.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 273 287 1.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 1.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 301 1.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 SUPERFAMILY SSF47384 111 180 3.53E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 Pfam PF00512 His Kinase A (phospho-acceptor) domain 121 181 7.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 SMART SM00388 120 189 3.6E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS11295 25b23b3d5424f943f0ce9af337363eaf 346 Gene3D G3DSA:3.30.565.10 185 344 3.7E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS06550 63c8fd7d61e674f4e348c54059f5e750 285 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 23 277 2.5E-97 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 hmeg3_RS06550 63c8fd7d61e674f4e348c54059f5e750 285 SUPERFAMILY SSF51717 13 277 6.54E-99 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS06550 63c8fd7d61e674f4e348c54059f5e750 285 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 57 70 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS06550 63c8fd7d61e674f4e348c54059f5e750 285 Pfam PF00809 Pterin binding enzyme 24 263 3.1E-81 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS06550 63c8fd7d61e674f4e348c54059f5e750 285 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 23 38 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 hmeg3_RS06550 63c8fd7d61e674f4e348c54059f5e750 285 Gene3D G3DSA:3.20.20.20 2 280 2.5E-108 T 28-03-2018 hmeg3_RS00995 f4314462e64080d36ca379339296a6b6 271 Pfam PF06764 Protein of unknown function (DUF1223) 42 255 1.6E-54 T 28-03-2018 IPR010634 Protein of unknown function DUF1223 hmeg3_RS00995 f4314462e64080d36ca379339296a6b6 271 Gene3D G3DSA:2.60.40.10 147 270 2.2E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS00995 f4314462e64080d36ca379339296a6b6 271 SUPERFAMILY SSF52833 36 269 6.27E-56 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS05140 f2da411029d17b1d77162ebaddcbe493 362 SUPERFAMILY SSF51395 1 360 4.89E-114 T 28-03-2018 hmeg3_RS05140 f2da411029d17b1d77162ebaddcbe493 362 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 339 1.3E-78 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 hmeg3_RS05140 f2da411029d17b1d77162ebaddcbe493 362 Gene3D G3DSA:3.20.20.70 3 362 4.1E-117 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PIRSF PIRSF000410 2 280 9.0E-94 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 Gene3D G3DSA:3.40.50.150 86 279 5.2E-42 T 28-03-2018 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 SUPERFAMILY SSF53335 87 276 5.34E-55 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 Pfam PF01739 CheR methyltransferase, SAM binding domain 87 270 1.1E-54 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 Pfam PF03705 CheR methyltransferase, all-alpha domain 21 70 1.1E-17 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 SUPERFAMILY SSF47757 11 86 6.28E-23 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 Gene3D G3DSA:1.10.155.10 11 85 4.5E-24 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 SMART SM00138 19 279 3.2E-95 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PRINTS PR00996 Glutamate methyltransferase family signature 219 233 1.2E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PRINTS PR00996 Glutamate methyltransferase family signature 41 54 1.2E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PRINTS PR00996 Glutamate methyltransferase family signature 80 92 1.2E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PRINTS PR00996 Glutamate methyltransferase family signature 147 163 1.2E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PRINTS PR00996 Glutamate methyltransferase family signature 238 261 1.2E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS08115 80bb6b35355e7d1f10e40399fba24ccb 288 PRINTS PR00996 Glutamate methyltransferase family signature 113 133 1.2E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 TIGRFAM TIGR03186 AKGDH_not_PDH: alpha-ketoglutarate dehydrogenase 11 883 0.0 T 28-03-2018 IPR017600 Alpha-ketoglutarate dehydrogenase hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 Gene3D G3DSA:3.40.50.970 60 480 8.4E-78 T 28-03-2018 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 Gene3D G3DSA:3.40.50.970 483 716 2.1E-63 T 28-03-2018 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 SUPERFAMILY SSF52518 61 478 1.91E-115 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 12 885 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 Gene3D G3DSA:3.40.50.920 723 895 9.0E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 201 309 7.1E-6 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 SUPERFAMILY SSF52922 720 882 7.18E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 PIRSF PIRSF000156 3 898 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 hmeg3_RS04000 1799acc2b5c7882738e2dc38eb24b8db 898 SUPERFAMILY SSF52518 484 710 3.34E-92 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS18270 c81d12d7f0d204077201429cb9c2724c 154 Gene3D G3DSA:1.20.1260.10 1 149 6.0E-22 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS18270 c81d12d7f0d204077201429cb9c2724c 154 Pfam PF09537 Domain of unknown function (DUF2383) 6 116 8.4E-36 T 28-03-2018 IPR019052 Domain of unknown function DUF2383 hmeg3_RS18270 c81d12d7f0d204077201429cb9c2724c 154 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 7 145 8.5E-43 T 28-03-2018 IPR011971 Conserved hypothetical protein CHP02284 hmeg3_RS18270 c81d12d7f0d204077201429cb9c2724c 154 PIRSF PIRSF029477 1 151 3.2E-55 T 28-03-2018 IPR016920 Uncharacterised conserved protein UCP029477 hmeg3_RS18170 11c0c21e3c55686fad4df3724c982501 302 SUPERFAMILY SSF161098 102 287 1.31E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS18170 11c0c21e3c55686fad4df3724c982501 302 Gene3D G3DSA:1.10.3720.10 42 301 9.6E-30 T 28-03-2018 hmeg3_RS18170 11c0c21e3c55686fad4df3724c982501 302 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 92 288 9.9E-77 T 28-03-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 hmeg3_RS18170 11c0c21e3c55686fad4df3724c982501 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 284 3.1E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS08380 41849fde58a22541e75b53c164dd0390 122 SUPERFAMILY SSF54995 1 102 8.89E-37 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08380 41849fde58a22541e75b53c164dd0390 122 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 22.0 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 hmeg3_RS08380 41849fde58a22541e75b53c164dd0390 122 Gene3D G3DSA:3.30.70.60 1 99 8.4E-31 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 hmeg3_RS08380 41849fde58a22541e75b53c164dd0390 122 Pfam PF01250 Ribosomal protein S6 3 91 1.8E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08380 41849fde58a22541e75b53c164dd0390 122 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 5.1E-33 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 7.5E-82 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 SUPERFAMILY SSF53223 1 121 2.21E-39 T 28-03-2018 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 Gene3D G3DSA:3.40.50.720 140 263 8.6E-42 T 28-03-2018 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 281 37.068 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 6.3E-39 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 Gene3D G3DSA:3.40.50.10860 11 139 1.8E-45 T 28-03-2018 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 280 3.4E-69 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 hmeg3_RS17595 70273080af018aecce304ce99e0bb1a0 281 SUPERFAMILY SSF51735 122 280 8.78E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06540 62e0b290c2345fb852f22a31289d32e6 214 PIRSF PIRSF005461 1 214 1.1E-67 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 hmeg3_RS06540 62e0b290c2345fb852f22a31289d32e6 214 Pfam PF01728 FtsJ-like methyltransferase 28 207 9.8E-50 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 hmeg3_RS06540 62e0b290c2345fb852f22a31289d32e6 214 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 211 28.636 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 hmeg3_RS06540 62e0b290c2345fb852f22a31289d32e6 214 Gene3D G3DSA:3.40.50.150 1 214 8.6E-46 T 28-03-2018 hmeg3_RS06540 62e0b290c2345fb852f22a31289d32e6 214 SUPERFAMILY SSF53335 3 213 2.02E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS21010 dbc017ea808333c8fbd31baf98855a11 270 PIRSF PIRSF002854 2 270 7.0E-84 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS21010 dbc017ea808333c8fbd31baf98855a11 270 Gene3D G3DSA:3.40.190.10 30 122 2.1E-16 T 28-03-2018 hmeg3_RS21010 dbc017ea808333c8fbd31baf98855a11 270 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 13 267 3.8E-70 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS21010 dbc017ea808333c8fbd31baf98855a11 270 Gene3D G3DSA:3.40.190.10 123 270 3.0E-43 T 28-03-2018 hmeg3_RS21010 dbc017ea808333c8fbd31baf98855a11 270 SUPERFAMILY SSF53850 31 270 1.24E-74 T 28-03-2018 hmeg3_RS21010 dbc017ea808333c8fbd31baf98855a11 270 Pfam PF03180 NLPA lipoprotein 31 270 6.5E-77 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS10110 0b55098b021dbd3e6037f19a1b159292 429 PIRSF PIRSF028135 1 428 9.9E-89 T 28-03-2018 IPR016869 Uncharacterised conserved protein UCP028135, HipA-like hmeg3_RS10110 0b55098b021dbd3e6037f19a1b159292 429 Pfam PF07804 HipA-like C-terminal domain 167 390 1.5E-28 T 28-03-2018 IPR012893 HipA-like, C-terminal hmeg3_RS13800 1eeed3b6844f7de005a105600d40c9ef 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS13800 1eeed3b6844f7de005a105600d40c9ef 253 Pfam PF00121 Triosephosphate isomerase 4 247 7.5E-90 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS13800 1eeed3b6844f7de005a105600d40c9ef 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.2E-60 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS13800 1eeed3b6844f7de005a105600d40c9ef 253 Gene3D G3DSA:3.20.20.70 1 253 1.5E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS13800 1eeed3b6844f7de005a105600d40c9ef 253 SUPERFAMILY SSF51351 1 249 7.07E-91 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS13800 1eeed3b6844f7de005a105600d40c9ef 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 40.565 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS08865 a127115217c4b7ca2945e4c02c09c836 359 Pfam PF13413 Helix-turn-helix domain 31 90 1.4E-20 T 28-03-2018 hmeg3_RS08865 a127115217c4b7ca2945e4c02c09c836 359 Pfam PF13464 Domain of unknown function (DUF4115) 285 358 7.7E-18 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 hmeg3_RS08865 a127115217c4b7ca2945e4c02c09c836 359 Gene3D G3DSA:1.10.260.40 16 100 2.5E-5 T 28-03-2018 hmeg3_RS10085 76691777fb122aecf5b38373e439ddfd 734 TIGRFAM TIGR03549 TIGR03549: YcaO domain protein 2 727 0.0 T 28-03-2018 IPR019938 YcaO domain protein hmeg3_RS10085 76691777fb122aecf5b38373e439ddfd 734 Pfam PF02566 OsmC-like protein 32 126 5.4E-10 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS10085 76691777fb122aecf5b38373e439ddfd 734 SUPERFAMILY SSF82784 1 124 2.88E-18 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS10085 76691777fb122aecf5b38373e439ddfd 734 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 159 550 5.2E-98 T 28-03-2018 IPR003776 YcaO-like domain hmeg3_RS10085 76691777fb122aecf5b38373e439ddfd 734 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 205 540 1.7E-69 T 28-03-2018 IPR003776 YcaO-like domain hmeg3_RS10085 76691777fb122aecf5b38373e439ddfd 734 Gene3D G3DSA:3.30.300.20 1 134 2.6E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS23540 04c0a84a847a0a9e3ae9ecf6de1e3b18 242 SUPERFAMILY SSF52540 1 234 1.66E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23540 04c0a84a847a0a9e3ae9ecf6de1e3b18 242 PIRSF PIRSF039085 1 241 3.0E-108 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS23540 04c0a84a847a0a9e3ae9ecf6de1e3b18 242 Gene3D G3DSA:3.40.50.300 1 242 1.1E-74 T 28-03-2018 hmeg3_RS23540 04c0a84a847a0a9e3ae9ecf6de1e3b18 242 Pfam PF00005 ABC transporter 17 165 3.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23540 04c0a84a847a0a9e3ae9ecf6de1e3b18 242 SMART SM00382 26 213 4.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23540 04c0a84a847a0a9e3ae9ecf6de1e3b18 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 170 1.4E-15 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 Gene3D G3DSA:1.10.287.950 318 514 4.4E-49 T 28-03-2018 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 Gene3D G3DSA:1.10.287.950 80 317 7.3E-19 T 28-03-2018 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 Pfam PF00672 HAMP domain 212 257 1.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 SMART SM00304 210 262 4.4E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 SMART SM00283 263 510 9.4E-94 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 SUPERFAMILY SSF58104 230 513 4.97E-77 T 28-03-2018 hmeg3_RS00405 3de4b2dbf6951761bd7c128419715a45 580 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 478 4.2E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04160 7871a8ff7dbe903d673ef9b6be76be22 367 Gene3D G3DSA:1.10.287.470 117 163 8.4E-7 T 28-03-2018 hmeg3_RS04160 7871a8ff7dbe903d673ef9b6be76be22 367 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 357 7.8E-65 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS04160 7871a8ff7dbe903d673ef9b6be76be22 367 Gene3D G3DSA:2.40.50.100 165 356 4.1E-8 T 28-03-2018 hmeg3_RS04160 7871a8ff7dbe903d673ef9b6be76be22 367 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 265 2.4E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS04160 7871a8ff7dbe903d673ef9b6be76be22 367 SUPERFAMILY SSF111369 53 279 5.75E-21 T 28-03-2018 hmeg3_RS04160 7871a8ff7dbe903d673ef9b6be76be22 367 Gene3D G3DSA:2.40.50.100 63 116 3.3E-11 T 28-03-2018 hmeg3_RS08670 3578cfea29879aa90751cc9af7f4ed2c 105 Pfam PF05247 Flagellar transcriptional activator (FlhD) 1 102 3.9E-45 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 hmeg3_RS08670 3578cfea29879aa90751cc9af7f4ed2c 105 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 10 97 2.0E-34 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 hmeg3_RS08670 3578cfea29879aa90751cc9af7f4ed2c 105 SUPERFAMILY SSF63592 1 97 1.44E-37 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 hmeg3_RS08670 3578cfea29879aa90751cc9af7f4ed2c 105 Gene3D G3DSA:1.10.4000.10 3 102 4.0E-39 T 28-03-2018 hmeg3_RS08670 3578cfea29879aa90751cc9af7f4ed2c 105 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 1 104 25.597 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 hmeg3_RS04640 608a6644c899fe7ca5b848a9b19313ba 329 Pfam PF05035 2-keto-3-deoxy-galactonokinase 10 321 9.5E-99 T 28-03-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 hmeg3_RS04640 608a6644c899fe7ca5b848a9b19313ba 329 Gene3D G3DSA:3.30.420.40 2 139 2.9E-4 T 28-03-2018 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Pfam PF13525 Outer membrane lipoprotein 130 253 1.4E-13 T 28-03-2018 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Gene3D G3DSA:1.20.120.330 4 133 1.3E-6 T 28-03-2018 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Gene3D G3DSA:1.10.150.200 134 179 0.0031 T 28-03-2018 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Gene3D G3DSA:1.25.40.10 180 216 1.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Gene3D G3DSA:1.25.40.10 217 249 0.0063 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 SUPERFAMILY SSF48452 136 247 2.02E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 10 252 20.635 T 28-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 Pfam PF16331 TolA binding protein trimerisation 45 118 7.7E-18 T 28-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 hmeg3_RS18120 e4a92ecee38ab8d2a168afc6ee305c37 253 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 131 249 5.9E-38 T 28-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal hmeg3_RS16970 fe17a9905d54cbc19f8d0cd53a9bf34c 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16970 fe17a9905d54cbc19f8d0cd53a9bf34c 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16970 fe17a9905d54cbc19f8d0cd53a9bf34c 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16970 fe17a9905d54cbc19f8d0cd53a9bf34c 326 Gene3D G3DSA:3.40.50.720 11 326 3.2E-58 T 28-03-2018 hmeg3_RS16970 fe17a9905d54cbc19f8d0cd53a9bf34c 326 SUPERFAMILY SSF51735 21 283 7.75E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS16970 fe17a9905d54cbc19f8d0cd53a9bf34c 326 Pfam PF00106 short chain dehydrogenase 24 226 2.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 SUPERFAMILY SSF82051 2 158 3.53E-54 T 28-03-2018 IPR006169 GTP1/OBG domain hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 Gene3D G3DSA:2.70.210.12 2 156 2.1E-51 T 28-03-2018 IPR006169 GTP1/OBG domain hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 Gene3D G3DSA:3.40.50.300 158 357 1.5E-34 T 28-03-2018 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 PIRSF PIRSF002401 1 363 3.2E-136 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 SUPERFAMILY SSF52540 151 345 3.7E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 8.0E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 8.0E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 8.0E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 8.0E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 Pfam PF01926 50S ribosome-binding GTPase 161 285 3.9E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 Pfam PF01018 GTP1/OBG 4 158 1.1E-55 T 28-03-2018 IPR006169 GTP1/OBG domain hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 3.7E-141 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 hmeg3_RS21875 a6a601e130970c76af0fbaff712155cd 369 Hamap MF_01454 GTPase Obg [obg]. 2 334 46.813 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 Gene3D G3DSA:1.10.540.10 16 138 1.2E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 PIRSF PIRSF016578 15 409 1.5E-35 T 28-03-2018 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 256 388 1.9E-21 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 SUPERFAMILY SSF56645 35 238 1.96E-54 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 24 412 8.0E-193 T 28-03-2018 IPR023922 Sulphate-starvation-induced SfnB hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 Gene3D G3DSA:2.40.110.10 139 236 7.0E-20 T 28-03-2018 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 153 229 6.0E-9 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 SUPERFAMILY SSF47203 248 410 5.64E-23 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 136 1.3E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS23165 1d4a6830616a296da5ebfe46812b199c 413 Gene3D G3DSA:1.20.140.10 237 412 1.6E-22 T 28-03-2018 hmeg3_RS07535 6684329b79ab6ead7cce0aeff8484788 231 SUPERFAMILY SSF52540 3 173 3.45E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07535 6684329b79ab6ead7cce0aeff8484788 231 Gene3D G3DSA:3.40.50.300 3 213 1.4E-5 T 28-03-2018 hmeg3_RS05550 0d6fa0710c13a390294401dda6e38b14 183 Pfam PF00293 NUDIX domain 50 144 4.1E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS05550 0d6fa0710c13a390294401dda6e38b14 183 Gene3D G3DSA:2.20.70.10 4 38 7.6E-7 T 28-03-2018 hmeg3_RS05550 0d6fa0710c13a390294401dda6e38b14 183 ProSitePatterns PS00893 Nudix box signature. 73 94 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 hmeg3_RS05550 0d6fa0710c13a390294401dda6e38b14 183 SUPERFAMILY SSF55811 3 166 2.57E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS05550 0d6fa0710c13a390294401dda6e38b14 183 Gene3D G3DSA:3.90.79.10 42 165 3.7E-17 T 28-03-2018 hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 SUPERFAMILY SSF53850 89 298 6.36E-44 T 28-03-2018 hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 Gene3D G3DSA:1.10.10.10 3 84 9.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 Pfam PF03466 LysR substrate binding domain 88 295 3.5E-37 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 Gene3D G3DSA:3.40.190.10 177 266 6.0E-19 T 28-03-2018 hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 Gene3D G3DSA:3.40.190.10 86 176 2.9E-20 T 28-03-2018 hmeg3_RS22280 0836de25b2cac306e352dfd2b8c4f4a3 301 SUPERFAMILY SSF46785 6 84 4.82E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 Pfam PF00005 ABC transporter 25 182 4.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 9.5E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 SMART SM00382 33 232 1.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.7E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 SUPERFAMILY SSF52540 4 253 3.06E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00450 de5641026d90f08b6d810881cb6868da 333 Gene3D G3DSA:3.40.50.300 1 332 6.3E-78 T 28-03-2018 hmeg3_RS03830 6c58834ba62c76934a1dc47b14c63331 173 Pfam PF16970 Type-1 fimbrial protein, A 51 173 1.7E-17 T 28-03-2018 hmeg3_RS03830 6c58834ba62c76934a1dc47b14c63331 173 SUPERFAMILY SSF49401 26 172 7.46E-29 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS03830 6c58834ba62c76934a1dc47b14c63331 173 Gene3D G3DSA:2.60.40.1090 25 172 4.1E-32 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS10600 d04a944c7d03a3d1cb3510feb830d1c7 309 SUPERFAMILY SSF103481 57 154 2.48E-8 T 28-03-2018 hmeg3_RS10600 d04a944c7d03a3d1cb3510feb830d1c7 309 Pfam PF00892 EamA-like transporter family 160 286 8.6E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS10600 d04a944c7d03a3d1cb3510feb830d1c7 309 Pfam PF00892 EamA-like transporter family 13 150 6.3E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS10600 d04a944c7d03a3d1cb3510feb830d1c7 309 SUPERFAMILY SSF103481 196 297 1.7E-16 T 28-03-2018 hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 SUPERFAMILY SSF141868 434 679 1.83E-81 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 SUPERFAMILY SSF55073 262 420 4.71E-52 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 Pfam PF00990 Diguanylate cyclase, GGDEF domain 257 414 8.7E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 Pfam PF00563 EAL domain 435 669 1.5E-73 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 255 417 4.7E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 SMART SM00052 428 674 1.1E-102 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 Pfam PF03707 Bacterial signalling protein N terminal repeat 115 162 8.3E-7 T 28-03-2018 IPR005330 MHYT domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 Pfam PF03707 Bacterial signalling protein N terminal repeat 52 108 7.6E-15 T 28-03-2018 IPR005330 MHYT domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 SMART SM00267 246 418 1.2E-63 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 Gene3D G3DSA:3.30.70.270 258 426 2.6E-64 T 28-03-2018 hmeg3_RS19655 9c754ad4c564c4c4be1e8e664cddfcda 686 Gene3D G3DSA:3.20.20.450 427 684 3.6E-96 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SUPERFAMILY SSF55785 41 153 3.49E-25 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Gene3D G3DSA:3.30.450.20 160 280 2.5E-30 T 28-03-2018 hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SUPERFAMILY SSF55073 293 450 2.67E-50 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Gene3D G3DSA:3.30.70.270 281 449 6.0E-60 T 28-03-2018 hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 284 449 1.2E-43 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Pfam PF00990 Diguanylate cyclase, GGDEF domain 288 445 2.5E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SMART SM00086 235 277 6.5E-5 T 28-03-2018 IPR001610 PAC motif hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SMART SM00086 113 155 1.6E-4 T 28-03-2018 IPR001610 PAC motif hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SUPERFAMILY SSF55785 156 275 8.7E-28 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Gene3D G3DSA:3.30.450.20 40 159 1.1E-27 T 28-03-2018 hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SMART SM00052 459 705 6.1E-96 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 160 4.3E-28 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 162 284 4.0E-32 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SUPERFAMILY SSF141868 465 714 1.44E-80 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SMART SM00091 41 107 1.6E-9 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SMART SM00091 163 229 4.5E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 SMART SM00267 277 449 1.8E-62 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Gene3D G3DSA:3.20.20.450 450 718 1.5E-86 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Pfam PF00989 PAS fold 163 274 6.9E-21 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Pfam PF00989 PAS fold 42 152 2.5E-17 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS12130 3b607fdfad07d6846c3401f21ac2f473 720 Pfam PF00563 EAL domain 465 700 1.0E-68 T 28-03-2018 IPR001633 EAL domain hmeg3_RS16040 1e40ebd2cec419665c3c73e085825dae 84 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.855 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16040 1e40ebd2cec419665c3c73e085825dae 84 Gene3D G3DSA:3.30.1320.10 1 79 1.0E-30 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16040 1e40ebd2cec419665c3c73e085825dae 84 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 1.1E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16040 1e40ebd2cec419665c3c73e085825dae 84 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS16040 1e40ebd2cec419665c3c73e085825dae 84 SUPERFAMILY SSF54565 1 76 8.37E-28 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16040 1e40ebd2cec419665c3c73e085825dae 84 Pfam PF00886 Ribosomal protein S16 8 68 7.8E-23 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 SUPERFAMILY SSF49503 126 285 5.27E-51 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 SUPERFAMILY SSF81464 15 113 1.8E-21 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 Gene3D G3DSA:1.10.287.90 24 109 1.0E-17 T 28-03-2018 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 154 225 4.3E-7 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 PIRSF PIRSF000292 1 316 2.7E-127 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 Pfam PF06481 COX Aromatic Rich Motif 243 287 7.3E-15 T 28-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 13 243 3.6E-106 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 hmeg3_RS11245 07b8d30d7f36a11ea2b94a2c65d78f61 333 Gene3D G3DSA:2.60.40.420 118 284 9.5E-53 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS09455 a48041a556f00b5dc6d3cf7222b0cecc 267 Pfam PF00005 ABC transporter 40 178 2.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09455 a48041a556f00b5dc6d3cf7222b0cecc 267 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09455 a48041a556f00b5dc6d3cf7222b0cecc 267 Gene3D G3DSA:3.40.50.300 20 238 2.0E-55 T 28-03-2018 hmeg3_RS09455 a48041a556f00b5dc6d3cf7222b0cecc 267 SMART SM00382 49 243 3.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09455 a48041a556f00b5dc6d3cf7222b0cecc 267 SUPERFAMILY SSF52540 23 246 7.56E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20710 6d0e582dad246bf66971bbf7301f9668 121 Pfam PF12643 MazG-like family 38 120 1.4E-12 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 hmeg3_RS20710 6d0e582dad246bf66971bbf7301f9668 121 Gene3D G3DSA:1.10.4010.10 1 120 4.5E-25 T 28-03-2018 hmeg3_RS20710 6d0e582dad246bf66971bbf7301f9668 121 PIRSF PIRSF029826 1 121 4.2E-45 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 hmeg3_RS20710 6d0e582dad246bf66971bbf7301f9668 121 SUPERFAMILY SSF101386 8 120 4.19E-37 T 28-03-2018 hmeg3_RS23400 7f7f01b87eaff7c9df697d35608a52f5 378 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 344 1.9E-87 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 hmeg3_RS23400 7f7f01b87eaff7c9df697d35608a52f5 378 SUPERFAMILY SSF51395 1 364 1.23E-116 T 28-03-2018 hmeg3_RS23400 7f7f01b87eaff7c9df697d35608a52f5 378 Gene3D G3DSA:3.20.20.70 6 377 4.9E-121 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS06915 ca88fae278c9dacdaafea365a035c3c0 233 Pfam PF02810 SEC-C motif 209 226 1.2E-9 T 28-03-2018 IPR004027 SEC-C motif hmeg3_RS06915 ca88fae278c9dacdaafea365a035c3c0 233 Gene3D G3DSA:3.10.450.50 58 228 6.5E-15 T 28-03-2018 hmeg3_RS06915 ca88fae278c9dacdaafea365a035c3c0 233 SUPERFAMILY SSF103642 206 226 3.11E-7 T 28-03-2018 hmeg3_RS06915 ca88fae278c9dacdaafea365a035c3c0 233 Pfam PF03695 Uncharacterised protein family (UPF0149) 13 189 3.0E-35 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 hmeg3_RS06915 ca88fae278c9dacdaafea365a035c3c0 233 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 12 189 8.1E-39 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 hmeg3_RS06915 ca88fae278c9dacdaafea365a035c3c0 233 SUPERFAMILY SSF101327 11 162 5.1E-22 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 Gene3D G3DSA:2.40.50.100 239 292 3.4E-12 T 28-03-2018 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 SUPERFAMILY SSF52540 4 242 1.73E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 Gene3D G3DSA:3.40.50.300 1 238 1.4E-69 T 28-03-2018 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 Gene3D G3DSA:2.40.50.140 293 345 5.8E-6 T 28-03-2018 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 Pfam PF08402 TOBE domain 281 352 2.7E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 Pfam PF00005 ABC transporter 20 161 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 SUPERFAMILY SSF50331 236 360 1.7E-24 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS21485 1ac6ecaa8d8ab63349c6ba096aa74740 370 SMART SM00382 28 211 3.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 242 255 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 6 550 6.2E-244 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 Gene3D G3DSA:3.20.20.70 9 375 2.0E-111 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 SUPERFAMILY SSF89000 387 437 2.55E-14 T 28-03-2018 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 SUPERFAMILY SSF110921 447 548 3.79E-34 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 SMART SM00917 421 550 6.1E-31 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 7 551 54.138 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 Pfam PF08502 LeuA allosteric (dimerisation) domain 421 548 2.9E-29 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 Pfam PF00682 HMGL-like 32 312 2.1E-76 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 SUPERFAMILY SSF51569 21 329 1.79E-101 T 28-03-2018 hmeg3_RS06955 77be2e5c5f37b1adb4f29f47eb717f39 567 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 39 55 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 SUPERFAMILY SSF48498 90 205 1.2E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 Gene3D G3DSA:1.10.357.10 71 204 2.3E-15 T 28-03-2018 hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 6.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 6.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 Gene3D G3DSA:1.10.10.60 14 70 7.2E-14 T 28-03-2018 hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 8.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS22360 a559220da4477a305375fc02cec01a7b 237 SUPERFAMILY SSF46689 15 82 9.23E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 SUPERFAMILY SSF46785 4 86 2.59E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 Gene3D G3DSA:3.40.190.10 180 267 6.0E-22 T 28-03-2018 hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 Pfam PF03466 LysR substrate binding domain 89 296 8.1E-37 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 Gene3D G3DSA:3.40.190.10 90 179 5.1E-8 T 28-03-2018 hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 Gene3D G3DSA:1.10.10.10 2 85 3.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20980 9651180350a940628bd4326d7213c25a 302 SUPERFAMILY SSF53850 90 299 5.25E-38 T 28-03-2018 hmeg3_RS04190 9bba188cd30f4159f2182271d98ae281 193 Pfam PF16036 Chalcone isomerase-like 61 190 1.4E-14 T 28-03-2018 IPR016087 Chalcone isomerase GO:0016872 hmeg3_RS04190 9bba188cd30f4159f2182271d98ae281 193 Gene3D G3DSA:3.50.70.10 52 174 1.3E-13 T 28-03-2018 IPR016088 Chalcone isomerase, 3-layer sandwich GO:0009813|GO:0045430 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 7 461 1.3E-169 T 28-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 Pfam PF01979 Amidohydrolase family 51 443 3.5E-28 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 Gene3D G3DSA:2.30.40.10 1 64 1.8E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 SUPERFAMILY SSF51556 55 389 8.04E-105 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 SUPERFAMILY SSF51338 5 80 1.65E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 Gene3D G3DSA:3.20.20.140 65 372 8.4E-92 T 28-03-2018 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 SUPERFAMILY SSF51338 360 460 6.21E-36 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS06110 1da6bd5f2ded1ca47424a7d3c8ac9dd4 472 Gene3D G3DSA:2.30.40.10 373 449 7.2E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS01920 39db2fe7f51066fedfe80c0254e77635 370 Gene3D G3DSA:3.40.640.10 11 246 5.6E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS01920 39db2fe7f51066fedfe80c0254e77635 370 SUPERFAMILY SSF53383 3 369 5.05E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS01920 39db2fe7f51066fedfe80c0254e77635 370 PIRSF PIRSF000390 1 370 4.9E-77 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS01920 39db2fe7f51066fedfe80c0254e77635 370 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 364 6.9E-82 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS01920 39db2fe7f51066fedfe80c0254e77635 370 Gene3D G3DSA:3.90.1150.10 247 370 1.8E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS02180 13bd3db8eb688b79f8447f76f6486b40 524 Gene3D G3DSA:1.20.1600.10 190 456 2.4E-21 T 28-03-2018 hmeg3_RS02180 13bd3db8eb688b79f8447f76f6486b40 524 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 210 501 1.0E-42 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS02180 13bd3db8eb688b79f8447f76f6486b40 524 SUPERFAMILY SSF111369 222 443 4.45E-24 T 28-03-2018 hmeg3_RS02180 13bd3db8eb688b79f8447f76f6486b40 524 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 208 439 1.2E-39 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 Gene3D G3DSA:3.40.50.720 2 254 6.9E-44 T 28-03-2018 hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 SUPERFAMILY SSF51735 5 252 1.18E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 Pfam PF00106 short chain dehydrogenase 12 196 5.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 53 1.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04205 362ede69db76fffbdb5c3694b33d842c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21400 32cccd2cbe8a3dadba8c02749cc7f692 471 SUPERFAMILY SSF51556 60 393 3.45E-88 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS21400 32cccd2cbe8a3dadba8c02749cc7f692 471 Gene3D G3DSA:2.30.40.10 3 73 2.7E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS21400 32cccd2cbe8a3dadba8c02749cc7f692 471 SUPERFAMILY SSF51338 23 60 1.66E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS21400 32cccd2cbe8a3dadba8c02749cc7f692 471 SUPERFAMILY SSF51338 394 468 1.66E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS21400 32cccd2cbe8a3dadba8c02749cc7f692 471 Pfam PF01979 Amidohydrolase family 58 441 6.1E-46 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS21400 32cccd2cbe8a3dadba8c02749cc7f692 471 Gene3D G3DSA:3.20.20.140 74 410 4.7E-49 T 28-03-2018 hmeg3_RS17880 cd9191eb8c44a3faf1545a1d3ee07f1f 126 Pfam PF12200 Domain of unknown function (DUF3597) 3 121 4.8E-47 T 28-03-2018 IPR022016 Domain of unknown function DUF3597 hmeg3_RS17880 cd9191eb8c44a3faf1545a1d3ee07f1f 126 SUPERFAMILY SSF158634 1 126 6.02E-45 T 28-03-2018 hmeg3_RS04690 09e813c1fd1e700424f99f7e92f25be7 242 Pfam PF00005 ABC transporter 18 165 8.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS04690 09e813c1fd1e700424f99f7e92f25be7 242 Gene3D G3DSA:3.40.50.300 1 241 2.3E-66 T 28-03-2018 hmeg3_RS04690 09e813c1fd1e700424f99f7e92f25be7 242 SUPERFAMILY SSF52540 1 235 2.78E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04690 09e813c1fd1e700424f99f7e92f25be7 242 PIRSF PIRSF039085 1 241 9.7E-100 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS04690 09e813c1fd1e700424f99f7e92f25be7 242 SMART SM00382 26 213 7.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04690 09e813c1fd1e700424f99f7e92f25be7 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS01100 3cc7df08e7abbee13784408d1eddf9a4 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 330 5.2E-19 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS01100 3cc7df08e7abbee13784408d1eddf9a4 346 Gene3D G3DSA:1.10.3470.10 99 337 8.3E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01100 3cc7df08e7abbee13784408d1eddf9a4 346 Gene3D G3DSA:1.10.3470.10 3 97 1.0E-6 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS10090 f9039d300ab61a62577e53091a07dbe2 204 Gene3D G3DSA:3.90.1140.10 29 204 1.4E-20 T 28-03-2018 hmeg3_RS10090 f9039d300ab61a62577e53091a07dbe2 204 SUPERFAMILY SSF55144 35 202 1.62E-19 T 28-03-2018 IPR009097 Cyclic phosphodiesterase hmeg3_RS10090 f9039d300ab61a62577e53091a07dbe2 204 Pfam PF13563 2'-5' RNA ligase superfamily 61 175 6.0E-9 T 28-03-2018 hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 Gene3D G3DSA:3.40.50.2300 167 315 4.6E-23 T 28-03-2018 hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 264 282 3.0E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 3.0E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 97 107 3.0E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 Pfam PF13458 Periplasmic binding protein 31 353 3.4E-45 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 SUPERFAMILY SSF53822 30 387 2.5E-50 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS19175 e926687883cde078d5d2fae17dc8dc93 396 Gene3D G3DSA:3.40.50.2300 27 166 1.4E-13 T 28-03-2018 hmeg3_RS22770 fa4a39d1edf248ee439222fccb1a0ad9 62 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 8 61 9.0E-24 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22770 fa4a39d1edf248ee439222fccb1a0ad9 62 Gene3D G3DSA:3.30.1390.20 8 62 1.2E-22 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain hmeg3_RS22770 fa4a39d1edf248ee439222fccb1a0ad9 62 SUPERFAMILY SSF55129 6 60 3.79E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain hmeg3_RS22770 fa4a39d1edf248ee439222fccb1a0ad9 62 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 5 62 20.058 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22770 fa4a39d1edf248ee439222fccb1a0ad9 62 PIRSF PIRSF002211 4 62 2.8E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22770 fa4a39d1edf248ee439222fccb1a0ad9 62 Pfam PF00327 Ribosomal protein L30p/L7e 8 58 2.8E-18 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain hmeg3_RS23405 a2c640f0cfc4241ba1c6f3fe8cbfaf33 285 Pfam PF00248 Aldo/keto reductase family 18 281 1.6E-60 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS23405 a2c640f0cfc4241ba1c6f3fe8cbfaf33 285 PRINTS PR00069 Aldo-keto reductase signature 216 240 4.4E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS23405 a2c640f0cfc4241ba1c6f3fe8cbfaf33 285 PRINTS PR00069 Aldo-keto reductase signature 112 130 4.4E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS23405 a2c640f0cfc4241ba1c6f3fe8cbfaf33 285 PRINTS PR00069 Aldo-keto reductase signature 143 160 4.4E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS23405 a2c640f0cfc4241ba1c6f3fe8cbfaf33 285 SUPERFAMILY SSF51430 8 281 3.67E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS23405 a2c640f0cfc4241ba1c6f3fe8cbfaf33 285 Gene3D G3DSA:3.20.20.100 6 285 2.8E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS16505 a3230ae75916cedf5bd9b08293c0e23e 338 Gene3D G3DSA:3.40.50.2300 24 138 1.1E-22 T 28-03-2018 hmeg3_RS16505 a3230ae75916cedf5bd9b08293c0e23e 338 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 34 335 6.6E-153 T 28-03-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 hmeg3_RS16505 a3230ae75916cedf5bd9b08293c0e23e 338 Gene3D G3DSA:3.40.50.2300 139 334 2.0E-35 T 28-03-2018 hmeg3_RS16505 a3230ae75916cedf5bd9b08293c0e23e 338 SUPERFAMILY SSF53822 30 321 4.21E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS16505 a3230ae75916cedf5bd9b08293c0e23e 338 Pfam PF13407 Periplasmic binding protein domain 35 292 2.3E-64 T 28-03-2018 IPR025997 Periplasmic binding protein hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 PIRSF PIRSF002741 7 525 3.6E-97 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 Gene3D G3DSA:3.90.76.10 42 184 7.7E-33 T 28-03-2018 hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 Gene3D G3DSA:3.40.190.10 185 307 1.5E-37 T 28-03-2018 hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 SUPERFAMILY SSF53850 34 512 4.52E-130 T 28-03-2018 hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 432 8.1E-89 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 81 102 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site hmeg3_RS12870 f987ba5995e1f1921cb6d53d8dfeae62 529 Gene3D G3DSA:3.10.105.10 308 502 4.1E-48 T 28-03-2018 hmeg3_RS02170 fe1d7fe944124948e3a0186c235044f8 113 Gene3D G3DSA:2.20.28.20 63 88 0.0015 T 28-03-2018 hmeg3_RS02170 fe1d7fe944124948e3a0186c235044f8 113 Pfam PF12773 Double zinc ribbon 64 108 1.5E-10 T 28-03-2018 IPR025874 Double zinc ribbon hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 Gene3D G3DSA:3.40.50.2300 174 318 4.3E-23 T 28-03-2018 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 SMART SM00260 17 161 5.5E-16 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 SMART SM00448 187 312 3.6E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 SUPERFAMILY SSF50341 17 163 5.36E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 Pfam PF01584 CheW-like domain 22 163 4.7E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 Gene3D G3DSA:2.40.50.180 45 108 1.2E-11 T 28-03-2018 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 SUPERFAMILY SSF52172 188 315 3.13E-22 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 Pfam PF00072 Response regulator receiver domain 189 311 7.7E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 Gene3D G3DSA:2.30.30.40 109 155 6.7E-7 T 28-03-2018 hmeg3_RS05865 c1c3b387cb44cd8aff517c143234e3f0 318 PIRSF PIRSF002867 1 318 1.5E-99 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV hmeg3_RS18290 293c8a36befe53cbf6d931ee37df3aef 405 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 372 1.7E-46 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS18290 293c8a36befe53cbf6d931ee37df3aef 405 Gene3D G3DSA:1.10.3470.10 41 376 1.6E-41 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS22510 293c8a36befe53cbf6d931ee37df3aef 405 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 372 1.7E-46 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS22510 293c8a36befe53cbf6d931ee37df3aef 405 Gene3D G3DSA:1.10.3470.10 41 376 1.6E-41 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS12890 25aab74e41e05ccf1dea9b2842a9aacd 337 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 33 288 3.4E-97 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS12890 25aab74e41e05ccf1dea9b2842a9aacd 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 316 1.2E-108 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS12890 25aab74e41e05ccf1dea9b2842a9aacd 337 PIRSF PIRSF006470 1 333 4.6E-137 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS12890 25aab74e41e05ccf1dea9b2842a9aacd 337 Gene3D G3DSA:3.40.190.10 183 335 8.5E-4 T 28-03-2018 hmeg3_RS18425 a0a841799bd7cef1ef535b848e2d03db 233 SUPERFAMILY SSF51182 1 231 1.98E-74 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS18425 a0a841799bd7cef1ef535b848e2d03db 233 Gene3D G3DSA:2.60.120.10 12 131 6.2E-48 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS18425 a0a841799bd7cef1ef535b848e2d03db 233 Pfam PF02678 Pirin 10 119 1.7E-33 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 hmeg3_RS18425 a0a841799bd7cef1ef535b848e2d03db 233 Gene3D G3DSA:2.60.120.10 132 233 3.1E-29 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS18425 a0a841799bd7cef1ef535b848e2d03db 233 PIRSF PIRSF006232 1 230 1.5E-53 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 Pfam PF01965 DJ-1/PfpI family 2 183 2.2E-7 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 Pfam PF12833 Helix-turn-helix domain 242 317 5.1E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 Gene3D G3DSA:1.10.10.60 226 269 1.4E-4 T 28-03-2018 hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 SUPERFAMILY SSF52317 1 199 3.05E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 Gene3D G3DSA:1.10.10.60 270 320 2.9E-4 T 28-03-2018 hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 SMART SM00342 234 316 3.7E-7 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS04095 4a87d0a737f828da3287c78e26fa4b72 320 Gene3D G3DSA:3.40.50.880 1 225 2.6E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS11235 79bfeb07b2bb0989d475a72c63dbb712 459 PIRSF PIRSF000337 7 450 1.1E-171 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS11235 79bfeb07b2bb0989d475a72c63dbb712 459 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 13 436 2.9E-186 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS11235 79bfeb07b2bb0989d475a72c63dbb712 459 Gene3D G3DSA:3.20.20.30 2 454 1.7E-118 T 28-03-2018 hmeg3_RS11235 79bfeb07b2bb0989d475a72c63dbb712 459 Pfam PF00296 Luciferase-like monooxygenase 22 394 5.8E-70 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS11235 79bfeb07b2bb0989d475a72c63dbb712 459 SUPERFAMILY SSF51679 9 442 1.14E-143 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS22560 78126b4773804cce74f05450bed10a3e 251 SUPERFAMILY SSF69572 2 247 1.44E-82 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 hmeg3_RS22560 78126b4773804cce74f05450bed10a3e 251 Gene3D G3DSA:3.40.50.720 1 248 6.8E-67 T 28-03-2018 hmeg3_RS22560 78126b4773804cce74f05450bed10a3e 251 Pfam PF00899 ThiF family 9 243 4.4E-60 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 hmeg3_RS01490 0c70978532379a5e300bf0b0d62ac106 392 Pfam PF03069 Acetamidase/Formamidase family 8 374 7.5E-158 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 hmeg3_RS01490 0c70978532379a5e300bf0b0d62ac106 392 Gene3D G3DSA:3.10.28.20 281 373 1.3E-15 T 28-03-2018 hmeg3_RS01490 0c70978532379a5e300bf0b0d62ac106 392 SUPERFAMILY SSF141130 204 373 1.22E-74 T 28-03-2018 hmeg3_RS01490 0c70978532379a5e300bf0b0d62ac106 392 SUPERFAMILY SSF141130 15 161 1.22E-74 T 28-03-2018 hmeg3_RS01490 0c70978532379a5e300bf0b0d62ac106 392 Gene3D G3DSA:2.60.120.580 147 272 3.9E-29 T 28-03-2018 hmeg3_RS01490 0c70978532379a5e300bf0b0d62ac106 392 Gene3D G3DSA:2.60.120.580 6 146 4.9E-31 T 28-03-2018 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 Gene3D G3DSA:1.10.287.950 34 328 6.2E-15 T 28-03-2018 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 Gene3D G3DSA:1.10.287.950 329 524 1.1E-45 T 28-03-2018 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 SUPERFAMILY SSF58104 250 520 1.96E-64 T 28-03-2018 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 190 1.1E-8 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 9.6E-53 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 10 9.6E-53 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 9.6E-53 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 448 477 9.6E-53 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 294 323 9.6E-53 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 488 2.7E-49 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20225 49a553bf5c4e3a4de5a252d3c3ad9877 548 SMART SM00283 273 520 1.4E-77 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS13290 74d41269bef16dd7b2c898f48f44dbec 202 Gene3D G3DSA:3.40.50.360 3 202 1.9E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS13290 74d41269bef16dd7b2c898f48f44dbec 202 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 202 33.017 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 hmeg3_RS13290 74d41269bef16dd7b2c898f48f44dbec 202 Pfam PF02525 Flavodoxin-like fold 3 200 4.6E-48 T 28-03-2018 IPR003680 Flavodoxin-like fold hmeg3_RS13290 74d41269bef16dd7b2c898f48f44dbec 202 SUPERFAMILY SSF52218 1 199 6.68E-57 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 Pfam PF03466 LysR substrate binding domain 88 292 4.2E-46 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 SUPERFAMILY SSF53850 90 293 1.23E-46 T 28-03-2018 hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 SUPERFAMILY SSF46785 4 87 8.05E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 Gene3D G3DSA:3.40.190.10 90 175 4.6E-15 T 28-03-2018 hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 Gene3D G3DSA:3.40.190.10 176 261 3.4E-24 T 28-03-2018 hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23395 5b1b8381af8e000f667bda8e657f60ae 294 Gene3D G3DSA:1.10.10.10 3 84 1.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00440 f57cea826a59a35472a1389252577ce8 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 291 1.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00440 f57cea826a59a35472a1389252577ce8 297 Gene3D G3DSA:1.10.3720.10 19 287 2.8E-34 T 28-03-2018 hmeg3_RS00440 f57cea826a59a35472a1389252577ce8 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 66 6.3E-10 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS00440 f57cea826a59a35472a1389252577ce8 297 SUPERFAMILY SSF161098 92 279 1.96E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS18130 4f1be59947298b051a5c92fe1288a0f8 330 Gene3D G3DSA:3.40.1570.10 13 157 3.9E-24 T 28-03-2018 hmeg3_RS18130 4f1be59947298b051a5c92fe1288a0f8 330 Gene3D G3DSA:3.40.1570.10 158 326 3.3E-34 T 28-03-2018 hmeg3_RS18130 4f1be59947298b051a5c92fe1288a0f8 330 Pfam PF05171 Haemin-degrading HemS.ChuX domain 195 323 6.3E-26 T 28-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 hmeg3_RS18130 4f1be59947298b051a5c92fe1288a0f8 330 SUPERFAMILY SSF144064 5 324 1.37E-76 T 28-03-2018 hmeg3_RS18130 4f1be59947298b051a5c92fe1288a0f8 330 Pfam PF06228 Haem utilisation ChuX/HutX 24 137 1.6E-18 T 28-03-2018 IPR010413 Heme utilization carrier protein HutX-like hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 SUPERFAMILY SSF53850 94 297 5.43E-39 T 28-03-2018 hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 Gene3D G3DSA:3.40.190.10 94 184 1.1E-17 T 28-03-2018 hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 SUPERFAMILY SSF46785 8 90 1.06E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 Gene3D G3DSA:1.10.10.10 2 86 4.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 Gene3D G3DSA:3.40.190.10 185 271 1.8E-20 T 28-03-2018 hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 Pfam PF03466 LysR substrate binding domain 93 297 7.8E-44 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS17825 0b6eefbab356c65def585bc1e7e5face 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.3E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 Pfam PF09130 Domain of unknown function (DUF1932) 199 269 1.8E-20 T 28-03-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 PIRSF PIRSF000103 3 305 7.5E-23 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 130 8.7E-9 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 Gene3D G3DSA:1.10.1040.10 181 295 1.1E-39 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 SUPERFAMILY SSF51735 10 170 9.65E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 SUPERFAMILY SSF48179 172 280 2.04E-33 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS19385 1050953f74d1a4d71d38cca6a8acd78b 315 Gene3D G3DSA:3.40.50.720 11 178 1.0E-18 T 28-03-2018 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 Pfam PF03466 LysR substrate binding domain 88 300 1.9E-27 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 Gene3D G3DSA:3.40.190.10 85 191 1.6E-16 T 28-03-2018 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 SUPERFAMILY SSF46785 1 87 5.03E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 SUPERFAMILY SSF53850 88 307 1.59E-28 T 28-03-2018 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 Gene3D G3DSA:3.40.190.10 192 272 2.6E-10 T 28-03-2018 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 Gene3D G3DSA:1.10.10.10 1 84 7.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS10705 14c2ea88173f77253db9e252a14b39a9 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS00270 fee2508cee0fdfdc38ca3a42b72776cf 204 PIRSF PIRSF016919 7 204 9.7E-58 T 28-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein hmeg3_RS00270 fee2508cee0fdfdc38ca3a42b72776cf 204 Pfam PF04955 HupE / UreJ protein 18 200 1.4E-59 T 28-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 SUPERFAMILY SSF50129 4 179 1.12E-46 T 28-03-2018 IPR011032 GroES-like hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 SUPERFAMILY SSF51735 144 309 3.94E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 Pfam PF00107 Zinc-binding dehydrogenase 180 304 1.3E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 Gene3D G3DSA:3.40.50.720 172 290 1.6E-25 T 28-03-2018 hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 1.7E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS05115 6f1ad290ff501aee1b8dfc8d594a0163 345 Gene3D G3DSA:3.90.180.10 1 171 1.3E-41 T 28-03-2018 hmeg3_RS02790 3430ded905bb49fd5382b16feced334d 112 SUPERFAMILY SSF52833 13 111 9.06E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02790 3430ded905bb49fd5382b16feced334d 112 Gene3D G3DSA:3.40.30.10 12 112 6.4E-27 T 28-03-2018 hmeg3_RS02790 3430ded905bb49fd5382b16feced334d 112 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 28 99 5.3E-7 T 28-03-2018 hmeg3_RS03745 bf5e81d82789bc14f7559ab7abbee22a 430 Gene3D G3DSA:3.30.9.10 195 351 5.1E-24 T 28-03-2018 hmeg3_RS03745 bf5e81d82789bc14f7559ab7abbee22a 430 Pfam PF01266 FAD dependent oxidoreductase 26 387 2.7E-60 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS03745 bf5e81d82789bc14f7559ab7abbee22a 430 SUPERFAMILY SSF51905 25 257 9.39E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03745 bf5e81d82789bc14f7559ab7abbee22a 430 SUPERFAMILY SSF51905 352 406 9.39E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03745 bf5e81d82789bc14f7559ab7abbee22a 430 Gene3D G3DSA:3.50.50.60 16 118 2.1E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03745 bf5e81d82789bc14f7559ab7abbee22a 430 Gene3D G3DSA:3.30.9.10 120 194 3.9E-4 T 28-03-2018 hmeg3_RS16945 cd982893b0120f15338e444b065cb915 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 2.3E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16945 cd982893b0120f15338e444b065cb915 293 Gene3D G3DSA:1.10.3470.10 1 282 8.8E-53 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 209 234 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 238 259 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 145 171 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 37 61 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 179 205 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PRINTS PR00083 Histidinol dehydrogenase signature 260 279 2.4E-82 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 PIRSF PIRSF000099 4 437 2.8E-157 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 SUPERFAMILY SSF53720 31 436 1.88E-87 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 39 435 1.1E-159 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 Gene3D G3DSA:3.40.50.1980 30 234 8.9E-84 T 28-03-2018 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 238 270 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 436 41.305 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 Gene3D G3DSA:3.40.50.1980 235 380 5.6E-69 T 28-03-2018 hmeg3_RS03480 83c858851be7a30903b2520691515857 437 Pfam PF00815 Histidinol dehydrogenase 28 436 3.0E-167 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 Gene3D G3DSA:1.25.40.70 275 357 0.0011 T 28-03-2018 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 SUPERFAMILY SSF54862 173 319 7.53E-17 T 28-03-2018 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 Gene3D G3DSA:3.30.70.20 84 203 2.5E-4 T 28-03-2018 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 Gene3D G3DSA:3.30.70.20 204 272 5.0E-8 T 28-03-2018 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 356 9.4E-143 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 Pfam PF13484 4Fe-4S double cluster binding domain 195 259 6.5E-20 T 28-03-2018 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 Pfam PF08331 Domain of unknown function (DUF1730) 59 143 2.6E-21 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 hmeg3_RS19735 7f94e70a61d8dd08bee059b34e3962de 358 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 4 318 48.303 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 hmeg3_RS09565 e74064b344009e20a13aec3511c70411 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 1.3E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09565 e74064b344009e20a13aec3511c70411 323 Gene3D G3DSA:1.10.3720.10 3 308 1.1E-41 T 28-03-2018 hmeg3_RS09565 e74064b344009e20a13aec3511c70411 323 SUPERFAMILY SSF161098 89 302 1.7E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14830 97bb3a73aae9ed4af92ed89dbceb04cc 170 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 12 143 4.7E-20 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily hmeg3_RS14830 97bb3a73aae9ed4af92ed89dbceb04cc 170 SUPERFAMILY SSF52788 10 147 4.45E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily hmeg3_RS14830 97bb3a73aae9ed4af92ed89dbceb04cc 170 SMART SM00226 10 148 1.3E-40 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily hmeg3_RS14830 97bb3a73aae9ed4af92ed89dbceb04cc 170 Gene3D G3DSA:3.40.50.2300 6 147 3.0E-39 T 28-03-2018 hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 202 3.1E-69 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 210 6.7E-81 T 28-03-2018 IPR010016 KipI family hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 SUPERFAMILY SSF160467 6 93 6.02E-10 T 28-03-2018 hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 Gene3D G3DSA:3.30.1360.40 5 82 3.6E-7 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 Gene3D G3DSA:2.40.100.10 86 216 4.9E-52 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 SMART SM00796 4 202 1.1E-95 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D hmeg3_RS13815 9f54cec80e5b861008aedfda13c65772 217 SUPERFAMILY SSF50891 88 212 4.17E-46 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 Gene3D G3DSA:3.40.50.720 3 238 8.0E-56 T 28-03-2018 hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.6E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.6E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.6E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 8.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 8.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 8.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 8.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 SUPERFAMILY SSF51735 3 237 2.44E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01580 f7715ca4e7397d5dfad4bc41c9f566e9 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 237 1.9E-45 T 28-03-2018 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 Hamap MF_00492 Transaldolase [tal]. 1 310 48.486 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 ProSitePatterns PS00958 Transaldolase active site. 121 138 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 305 3.1E-98 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 Gene3D G3DSA:3.20.20.70 1 310 7.6E-115 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 TIGRFAM TIGR00874 talAB: transaldolase 2 308 6.0E-139 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 hmeg3_RS17875 09c1116488953e315022cb49e49a4b58 313 SUPERFAMILY SSF51569 1 309 2.41E-108 T 28-03-2018 hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 339 507 1.7E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 Gene3D G3DSA:3.30.70.270 336 507 1.3E-52 T 28-03-2018 hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 Gene3D G3DSA:3.30.450.20 45 172 4.3E-17 T 28-03-2018 hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 SUPERFAMILY SSF55073 348 506 5.02E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 Pfam PF00990 Diguanylate cyclase, GGDEF domain 343 504 3.1E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 SMART SM00267 332 507 2.1E-67 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 Pfam PF02743 Cache domain 45 274 2.7E-21 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS05855 7e79aff374baeb6c3dda5afefd64015b 507 Gene3D G3DSA:3.30.450.20 173 289 1.2E-14 T 28-03-2018 hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 251 2.0E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 SMART SM00079 35 252 1.5E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 SMART SM00062 35 253 3.3E-67 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 Gene3D G3DSA:3.40.190.10 178 255 7.9E-12 T 28-03-2018 hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 Gene3D G3DSA:3.40.190.10 24 177 4.7E-40 T 28-03-2018 hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS23230 cdf1e678ba97f27bb13f0b92cc748bc3 255 SUPERFAMILY SSF53850 5 251 6.14E-67 T 28-03-2018 hmeg3_RS20195 4417e2fa2ccca07c2a2b1d93462680e4 318 Pfam PF04280 Tim44-like domain 193 316 2.3E-17 T 28-03-2018 IPR007379 Tim44-like domain hmeg3_RS20195 4417e2fa2ccca07c2a2b1d93462680e4 318 SUPERFAMILY SSF54427 195 317 4.12E-12 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS20195 4417e2fa2ccca07c2a2b1d93462680e4 318 SMART SM00978 185 316 7.7E-40 T 28-03-2018 IPR007379 Tim44-like domain hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 SUPERFAMILY SSF53633 9 293 1.54E-64 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 442 210.275 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 Pfam PF00696 Amino acid kinase family 30 268 1.1E-22 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 Gene3D G3DSA:3.40.630.30 297 441 4.1E-18 T 28-03-2018 hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 Gene3D G3DSA:3.40.1160.10 11 295 1.7E-57 T 28-03-2018 hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 Pfam PF00583 Acetyltransferase (GNAT) family 329 404 8.8E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 SUPERFAMILY SSF55729 298 419 2.84E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 PIRSF PIRSF000423 3 442 4.9E-183 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS17775 f57a040559ba8296e2fd6cdf3b6db09b 442 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 13 442 1.8E-187 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS22525 6d766f01610643d49198bfe9355f8b96 336 SUPERFAMILY SSF54506 3 333 3.36E-105 T 28-03-2018 hmeg3_RS22525 6d766f01610643d49198bfe9355f8b96 336 Gene3D G3DSA:3.10.310.10 154 311 6.4E-54 T 28-03-2018 hmeg3_RS22525 6d766f01610643d49198bfe9355f8b96 336 Pfam PF05544 Proline racemase 11 333 1.8E-109 T 28-03-2018 IPR008794 Proline racemase family hmeg3_RS22525 6d766f01610643d49198bfe9355f8b96 336 PIRSF PIRSF029792 2 336 1.4E-118 T 28-03-2018 IPR008794 Proline racemase family hmeg3_RS22525 6d766f01610643d49198bfe9355f8b96 336 Gene3D G3DSA:3.10.310.10 1 153 1.1E-35 T 28-03-2018 hmeg3_RS10310 99e36e48c50298e52821bdf2353278ac 95 Pfam PF16290 Domain of unknown function (DUF4936) 4 88 5.7E-26 T 28-03-2018 IPR032556 Protein of unknown function DUF4936 hmeg3_RS18275 9acc77b09956da9f8d33820b12370336 189 Gene3D G3DSA:3.40.50.360 1 189 5.3E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS18275 9acc77b09956da9f8d33820b12370336 189 SUPERFAMILY SSF52218 7 174 7.54E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS18275 9acc77b09956da9f8d33820b12370336 189 Pfam PF03358 NADPH-dependent FMN reductase 7 151 2.0E-36 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS15790 8027210b2d4525535e192358ad63b390 256 Pfam PF01311 Bacterial export proteins, family 1 16 235 4.9E-49 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS15790 8027210b2d4525535e192358ad63b390 256 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 8 253 9.9E-80 T 28-03-2018 IPR006304 Type III secretion protein SpaR/YscT GO:0006810|GO:0016021 hmeg3_RS15790 8027210b2d4525535e192358ad63b390 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 200 219 1.8E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS15790 8027210b2d4525535e192358ad63b390 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 178 200 1.8E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS15790 8027210b2d4525535e192358ad63b390 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 1.8E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS15790 8027210b2d4525535e192358ad63b390 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.8E-29 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 hmeg3_RS08195 ab921d55fcc2902472ef092772aa3486 134 Pfam PF00460 Flagella basal body rod protein 7 32 4.4E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 hmeg3_RS08195 ab921d55fcc2902472ef092772aa3486 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 133 2.9E-53 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 hmeg3_RS08195 ab921d55fcc2902472ef092772aa3486 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 87 131 1.1E-14 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain hmeg3_RS08195 ab921d55fcc2902472ef092772aa3486 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site hmeg3_RS12670 0d0796e7cee1a8b23dac84e72e6b95f2 233 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 7 211 4.0E-49 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 hmeg3_RS12670 0d0796e7cee1a8b23dac84e72e6b95f2 233 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 7 212 7.0E-52 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 hmeg3_RS09420 4f046dd1eeb988d1e4960b5eea6a019e 249 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09420 4f046dd1eeb988d1e4960b5eea6a019e 249 Pfam PF00005 ABC transporter 15 154 1.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09420 4f046dd1eeb988d1e4960b5eea6a019e 249 SMART SM00382 24 217 5.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09420 4f046dd1eeb988d1e4960b5eea6a019e 249 Gene3D G3DSA:3.40.50.300 1 226 2.0E-57 T 28-03-2018 hmeg3_RS09420 4f046dd1eeb988d1e4960b5eea6a019e 249 SUPERFAMILY SSF52540 11 209 4.9E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 Gene3D G3DSA:1.10.287.950 321 498 6.9E-40 T 28-03-2018 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 Gene3D G3DSA:1.20.120.30 20 176 4.5E-7 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 314 487 4.0E-35 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 SMART SM00283 261 494 1.6E-56 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 SUPERFAMILY SSF58104 242 495 1.74E-54 T 28-03-2018 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 116 1.1E-11 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 Gene3D G3DSA:1.20.120.570 229 320 0.011 T 28-03-2018 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 352 379 3.1E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 275 304 3.1E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 181 201 3.1E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 22 3.1E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20330 1238500ddc2ceea7f4a3e39d64d51d2e 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 410 3.1E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12375 118d89eff4143cbcd8159844737004dd 198 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 184 3.7E-59 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS12375 118d89eff4143cbcd8159844737004dd 198 SUPERFAMILY SSF52540 5 185 1.67E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12375 118d89eff4143cbcd8159844737004dd 198 PIRSF PIRSF006135 3 187 2.0E-55 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS12375 118d89eff4143cbcd8159844737004dd 198 Gene3D G3DSA:3.40.50.300 5 185 8.0E-62 T 28-03-2018 hmeg3_RS18430 e139451cc4f7b6c02a5999e359dd0b1c 204 Gene3D G3DSA:3.40.50.360 2 204 1.2E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS18430 e139451cc4f7b6c02a5999e359dd0b1c 204 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 202 32.999 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 hmeg3_RS18430 e139451cc4f7b6c02a5999e359dd0b1c 204 Pfam PF02525 Flavodoxin-like fold 3 198 1.2E-48 T 28-03-2018 IPR003680 Flavodoxin-like fold hmeg3_RS18430 e139451cc4f7b6c02a5999e359dd0b1c 204 SUPERFAMILY SSF52218 1 202 7.9E-59 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS01955 358c86f59098bf7bfbedd622f3603241 242 Pfam PF01755 Glycosyltransferase family 25 (LPS biosynthesis protein) 2 182 8.1E-23 T 28-03-2018 IPR002654 Glycosyl transferase, family 25 hmeg3_RS16560 0f0622379a293cb66bc0f1f80a7206ee 346 Pfam PF03060 Nitronate monooxygenase 3 343 1.3E-77 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 hmeg3_RS16560 0f0622379a293cb66bc0f1f80a7206ee 346 Gene3D G3DSA:3.20.20.70 3 346 6.9E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS16560 0f0622379a293cb66bc0f1f80a7206ee 346 SUPERFAMILY SSF51412 101 346 2.29E-64 T 28-03-2018 hmeg3_RS16560 0f0622379a293cb66bc0f1f80a7206ee 346 SUPERFAMILY SSF51412 5 72 2.29E-64 T 28-03-2018 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 Gene3D G3DSA:3.40.50.720 192 342 1.6E-26 T 28-03-2018 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 Gene3D G3DSA:3.90.180.10 1 191 1.4E-54 T 28-03-2018 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 SUPERFAMILY SSF50129 3 200 1.48E-58 T 28-03-2018 IPR011032 GroES-like hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 Pfam PF00107 Zinc-binding dehydrogenase 204 321 1.0E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 SUPERFAMILY SSF50129 323 374 7.06E-5 T 28-03-2018 IPR011032 GroES-like hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 160 7.1E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 SMART SM00829 18 368 2.0E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS12895 54373fc2b4a1bc0a071c77f37ef409f5 374 SUPERFAMILY SSF51735 166 338 8.11E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 150 775 9.3E-275 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Gene3D G3DSA:2.60.40.1180 680 777 4.7E-30 T 28-03-2018 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 PIRSF PIRSF000463 25 777 2.6E-283 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 SUPERFAMILY SSF51011 670 776 6.95E-29 T 28-03-2018 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 166 249 2.5E-22 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Pfam PF00128 Alpha amylase, catalytic domain 312 389 2.5E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 SUPERFAMILY SSF51445 214 663 6.94E-114 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Gene3D G3DSA:2.60.40.10 21 148 0.032 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 674 776 4.9E-19 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Gene3D G3DSA:3.20.20.80 291 679 9.7E-78 T 28-03-2018 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 SMART SM00642 294 663 1.9E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Gene3D G3DSA:2.60.40.10 153 290 1.0E-33 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 142 777 44.651 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 hmeg3_RS11330 ba17558a21df0dfb1cc0754ab867e7bd 777 SUPERFAMILY SSF81296 158 264 5.95E-32 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS14060 20be6292babbe5042f8b9bcb4c01f17a 340 Pfam PF00419 Fimbrial protein 206 339 3.7E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS14060 20be6292babbe5042f8b9bcb4c01f17a 340 Gene3D G3DSA:2.60.40.1090 197 340 5.2E-21 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS14060 20be6292babbe5042f8b9bcb4c01f17a 340 SUPERFAMILY SSF49401 207 339 4.72E-16 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS14655 32cac9bdee49b4c9bd38976548f63620 195 Pfam PF13302 Acetyltransferase (GNAT) domain 15 153 4.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS14655 32cac9bdee49b4c9bd38976548f63620 195 SUPERFAMILY SSF55729 4 178 2.6E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS14655 32cac9bdee49b4c9bd38976548f63620 195 Gene3D G3DSA:3.40.630.30 1 195 1.1E-24 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SUPERFAMILY SSF52335 939 1075 1.44E-38 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SMART SM00851 959 1046 1.5E-27 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1072 13.335 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Pfam PF02142 MGS-like domain 960 1046 6.8E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:1.10.1030.10 403 534 9.4E-52 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SUPERFAMILY SSF48108 396 549 1.57E-52 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SUPERFAMILY SSF52440 552 671 1.24E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:3.40.50.1380 932 1071 3.0E-36 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.2E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:3.40.50.20 535 650 3.8E-62 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SUPERFAMILY SSF52440 1 127 4.32E-51 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1067 13.089 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SUPERFAMILY SSF56059 128 401 8.49E-108 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SMART SM01096 419 543 7.0E-76 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 878 1.6E-33 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 5.1E-72 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:3.40.50.20 4 128 1.5E-39 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 SUPERFAMILY SSF56059 669 937 1.77E-100 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:3.30.1490.20 651 739 1.1E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:3.30.470.20 740 931 3.8E-41 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Gene3D G3DSA:3.30.470.20 129 402 8.5E-66 T 28-03-2018 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1056 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS06525 9b661814e84f9a5f01668c24557492c5 1077 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 422 543 2.2E-41 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 Pfam PF01795 MraW methylase family 9 313 1.0E-103 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 10 313 1.2E-106 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 Gene3D G3DSA:1.10.150.170 118 221 1.2E-37 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 SUPERFAMILY SSF53335 11 119 2.16E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 SUPERFAMILY SSF53335 219 313 2.16E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 SUPERFAMILY SSF81799 120 219 1.16E-34 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 11 314 36.799 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS22050 d09a2bdfe9bcdffd2b162346ba7028a8 320 PIRSF PIRSF004486 5 315 3.9E-98 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 Gene3D G3DSA:3.40.190.10 179 265 3.6E-18 T 28-03-2018 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 Gene3D G3DSA:1.10.10.10 1 83 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18630 585366a25f924896666b5193705348ee 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 SUPERFAMILY SSF46785 1 86 5.95E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18630 585366a25f924896666b5193705348ee 297 SUPERFAMILY SSF53850 90 292 6.15E-34 T 28-03-2018 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 Pfam PF03466 LysR substrate binding domain 88 290 6.9E-38 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS18630 585366a25f924896666b5193705348ee 297 Gene3D G3DSA:3.40.190.10 89 178 1.1E-15 T 28-03-2018 hmeg3_RS18630 585366a25f924896666b5193705348ee 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 Gene3D G3DSA:3.40.190.10 92 177 4.0E-17 T 28-03-2018 hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 SUPERFAMILY SSF46785 5 101 1.36E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 Gene3D G3DSA:3.40.190.10 178 269 3.2E-21 T 28-03-2018 hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 Gene3D G3DSA:1.10.10.10 1 86 3.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 SUPERFAMILY SSF53850 93 300 2.44E-40 T 28-03-2018 hmeg3_RS18155 be19de441c13a1e60afd3ea3f5386a1f 304 Pfam PF03466 LysR substrate binding domain 91 293 1.6E-42 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS00595 16198456d3770e6c90ad8c85661a22ef 138 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 6 133 25.905 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 hmeg3_RS00595 16198456d3770e6c90ad8c85661a22ef 138 Gene3D G3DSA:3.10.450.50 8 136 2.1E-40 T 28-03-2018 hmeg3_RS00595 16198456d3770e6c90ad8c85661a22ef 138 SUPERFAMILY SSF54427 29 134 2.27E-32 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 12 720 7.1E-300 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 16 104 7.0E-15 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 SUPERFAMILY SSF51445 156 478 4.56E-117 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 SUPERFAMILY SSF51445 507 583 4.56E-117 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 Gene3D G3DSA:2.60.40.1180 590 723 1.4E-19 T 28-03-2018 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 Gene3D G3DSA:3.20.20.80 153 589 1.6E-98 T 28-03-2018 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 Pfam PF00128 Alpha amylase, catalytic domain 201 357 1.7E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 SUPERFAMILY SSF51011 598 720 3.6E-12 T 28-03-2018 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 SMART SM00642 181 577 1.0E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 SUPERFAMILY SSF81296 12 149 8.75E-43 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS11335 aeadbc7be14d431fce92d3eb9503137a 726 Gene3D G3DSA:2.60.40.10 11 147 4.4E-42 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 SMART SM00387 355 450 3.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 Gene3D G3DSA:3.30.450.20 25 202 7.9E-48 T 28-03-2018 hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 448 2.0E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 Pfam PF17200 Single Cache domain 2 47 191 5.7E-39 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 Gene3D G3DSA:3.30.565.10 274 449 2.3E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 SMART SM01049 42 131 3.4E-28 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 SUPERFAMILY SSF55874 334 447 4.32E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 PIRSF PIRSF037314 1 455 7.6E-167 T 28-03-2018 IPR017171 Signal transduction histidine kinase, MctS hmeg3_RS18730 158fbc7ecdd151c07abbb732365c612a 456 Pfam PF07730 Histidine kinase 248 317 2.0E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Gene3D G3DSA:1.10.1200.10 966 1053 1.4E-16 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Gene3D G3DSA:3.30.559.10 6 214 9.8E-17 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 885 3.0E-107 T 28-03-2018 IPR010071 Amino acid adenylation domain hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 SUPERFAMILY SSF52777 194 435 9.64E-20 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Gene3D G3DSA:3.40.50.980 614 770 9.1E-30 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 SUPERFAMILY SSF47336 976 1047 3.53E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Gene3D G3DSA:3.40.50.980 451 613 8.2E-40 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 SMART SM00823 Phosphopantetheine attachment site 978 1050 9.8E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Pfam PF00550 Phosphopantetheine attachment site 996 1046 2.2E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Pfam PF00668 Condensation domain 26 428 4.6E-35 T 28-03-2018 IPR001242 Condensation domain hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Gene3D G3DSA:2.30.38.10 773 854 5.8E-15 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 SUPERFAMILY SSF56801 422 958 1.83E-120 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1005 1020 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Gene3D G3DSA:3.30.300.30 856 965 2.2E-28 T 28-03-2018 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 Pfam PF00501 AMP-binding enzyme 460 861 7.8E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 ProSitePatterns PS00455 Putative AMP-binding domain signature. 607 618 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS11655 07f6cca38c97e6ed8e5817692dd60ed1 1081 SUPERFAMILY SSF52777 26 186 5.34E-19 T 28-03-2018 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 1.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 1.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 1.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 81 1.6E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 Gene3D G3DSA:1.10.287.990 20 82 8.3E-27 T 28-03-2018 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 1.5E-37 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 SUPERFAMILY SSF54719 82 191 7.59E-41 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 PIRSF PIRSF000349 1 192 1.7E-81 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS18415 98086533621599030b62d412939f6b97 192 SUPERFAMILY SSF46609 1 83 3.4E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 Gene3D G3DSA:3.30.450.20 170 286 1.2E-11 T 28-03-2018 hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 SMART SM00267 329 505 2.7E-65 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 Pfam PF00990 Diguanylate cyclase, GGDEF domain 340 501 2.1E-48 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 Pfam PF02743 Cache domain 57 253 6.5E-17 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 Gene3D G3DSA:3.30.70.270 333 511 7.4E-53 T 28-03-2018 hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 Gene3D G3DSA:3.30.450.20 35 169 6.6E-19 T 28-03-2018 hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 336 503 7.1E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 SUPERFAMILY SSF55073 345 503 3.22E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS01835 09ccb550e84348c314fb70807b2f6308 517 SUPERFAMILY SSF103190 102 193 7.45E-5 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 285 8.4E-14 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 PIRSF PIRSF000103 1 294 1.5E-72 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 Gene3D G3DSA:3.40.50.720 1 164 6.5E-35 T 28-03-2018 hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 SUPERFAMILY SSF51735 1 163 2.68E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 Gene3D G3DSA:1.10.1040.10 165 292 1.6E-17 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 163 8.3E-44 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 hmeg3_RS06260 e6f237d9e81eb7c132c9841d05332805 295 SUPERFAMILY SSF48179 167 290 3.4E-19 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS04185 41b8f499b6debbe5ce97bee70cea8705 406 Pfam PF02353 Mycolic acid cyclopropane synthetase 134 401 1.1E-85 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS04185 41b8f499b6debbe5ce97bee70cea8705 406 PIRSF PIRSF003085 16 406 2.5E-126 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 hmeg3_RS04185 41b8f499b6debbe5ce97bee70cea8705 406 Gene3D G3DSA:3.40.50.150 127 405 7.7E-70 T 28-03-2018 hmeg3_RS04185 41b8f499b6debbe5ce97bee70cea8705 406 SUPERFAMILY SSF53335 140 405 9.34E-77 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 SMART SM00304 212 264 3.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 480 5.4E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 Gene3D G3DSA:1.20.120.30 23 174 3.8E-16 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 SMART SM00283 265 512 3.7E-95 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 Gene3D G3DSA:1.10.287.950 175 316 1.7E-12 T 28-03-2018 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 SUPERFAMILY SSF58104 232 520 2.22E-78 T 28-03-2018 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 7.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 7.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 7.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 7.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 Gene3D G3DSA:1.10.287.950 317 516 3.5E-50 T 28-03-2018 hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 183 2.4E-24 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS19885 b85ead684fd5b5276f08b906cbbd0404 567 Pfam PF00672 HAMP domain 212 259 3.8E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS20405 68cdf2f75fdc0bf90bbb50f67ed48f35 305 SUPERFAMILY SSF111331 15 296 1.44E-87 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain hmeg3_RS20405 68cdf2f75fdc0bf90bbb50f67ed48f35 305 Gene3D G3DSA:2.60.200.30 150 271 3.9E-41 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 hmeg3_RS20405 68cdf2f75fdc0bf90bbb50f67ed48f35 305 Gene3D G3DSA:3.40.50.10330 10 149 2.6E-38 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 hmeg3_RS20405 68cdf2f75fdc0bf90bbb50f67ed48f35 305 Pfam PF01513 ATP-NAD kinase 66 277 4.4E-59 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 hmeg3_RS20405 68cdf2f75fdc0bf90bbb50f67ed48f35 305 Hamap MF_00361 NAD kinase [nadK]. 14 294 32.373 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 SMART SM00346 13 101 1.3E-5 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 Gene3D G3DSA:3.30.450.40 86 251 3.3E-38 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 Pfam PF01614 Bacterial transcriptional regulator 129 244 6.3E-16 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 Pfam PF09339 IclR helix-turn-helix domain 17 65 6.5E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 SUPERFAMILY SSF55781 79 249 1.77E-36 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 Gene3D G3DSA:1.10.10.10 1 72 2.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23225 1f38566ec720d90291a5e9d72732c2ca 252 SUPERFAMILY SSF46785 13 81 3.11E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00065 401 556 0.0016 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00086 95 137 3.2E-6 T 28-03-2018 IPR001610 PAC motif hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00086 344 386 0.0056 T 28-03-2018 IPR001610 PAC motif hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00086 217 259 5.3E-4 T 28-03-2018 IPR001610 PAC motif hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SUPERFAMILY SSF55785 32 134 1.26E-23 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Gene3D G3DSA:3.40.50.10600 14 136 9.6E-28 T 28-03-2018 hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Gene3D G3DSA:3.40.50.10600 137 254 5.8E-28 T 28-03-2018 hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SUPERFAMILY SSF141868 734 983 2.09E-86 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Gene3D G3DSA:3.20.20.450 727 987 5.5E-99 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00091 271 338 0.014 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00091 142 212 0.076 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00091 20 90 0.051 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Gene3D G3DSA:3.30.450.20 259 387 5.7E-21 T 28-03-2018 hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SUPERFAMILY SSF55785 280 384 1.38E-19 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Pfam PF00990 Diguanylate cyclase, GGDEF domain 559 714 1.3E-47 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SUPERFAMILY SSF55781 405 559 7.85E-21 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Gene3D G3DSA:3.30.450.40 388 556 1.9E-18 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Gene3D G3DSA:3.30.70.270 557 726 2.0E-60 T 28-03-2018 hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SUPERFAMILY SSF55073 564 721 1.57E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 557 716 1.1E-44 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00052 729 975 8.5E-111 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Pfam PF13426 PAS domain 282 384 3.0E-16 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Pfam PF13426 PAS domain 34 136 4.4E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SUPERFAMILY SSF55785 152 256 6.93E-23 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 PIRSF PIRSF005925 259 987 2.0E-260 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 PIRSF PIRSF005925 160 264 3.0 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 PIRSF PIRSF005925 14 166 1.2E-7 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Pfam PF00563 EAL domain 735 970 3.3E-72 T 28-03-2018 IPR001633 EAL domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Pfam PF08447 PAS fold 167 252 1.2E-12 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 264 2.5E-9 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 273 390 1.7E-13 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 140 2.8E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 SMART SM00267 548 719 1.4E-62 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS19765 9e4faeb8a99966f261c8f5cc3e66c22d 989 Pfam PF13185 GAF domain 404 547 1.1E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 hmeg3_RS13245 cc0bc7dd512d7b82ee7018c0ae64b672 400 SUPERFAMILY SSF109604 200 395 1.44E-28 T 28-03-2018 hmeg3_RS13245 cc0bc7dd512d7b82ee7018c0ae64b672 400 Pfam PF08668 HDOD domain 207 316 3.5E-14 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS13245 cc0bc7dd512d7b82ee7018c0ae64b672 400 Gene3D G3DSA:1.10.3210.10 190 373 3.5E-17 T 28-03-2018 hmeg3_RS09600 036c9b11346c872eb00f7445a229f6ab 119 Gene3D G3DSA:1.10.10.10 50 113 9.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 SUPERFAMILY SSF55326 4 137 1.5E-35 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 301 4.3E-10 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 SUPERFAMILY SSF56042 142 305 3.29E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 28 137 5.9E-26 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 Gene3D G3DSA:3.30.1330.10 1 143 3.6E-37 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 319 2.1E-100 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 316 29.605 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 PIRSF PIRSF005303 1 319 1.9E-83 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 hmeg3_RS07195 a8acd72e9f0127b773541bf1f59add39 321 Gene3D G3DSA:3.90.650.10 144 320 9.0E-48 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS03905 821659910d5527627e0dadce89e0fa37 364 Gene3D G3DSA:1.20.1600.10 61 281 7.2E-25 T 28-03-2018 hmeg3_RS03905 821659910d5527627e0dadce89e0fa37 364 SUPERFAMILY SSF111369 42 270 8.76E-19 T 28-03-2018 hmeg3_RS03905 821659910d5527627e0dadce89e0fa37 364 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 53 264 1.7E-23 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS03905 821659910d5527627e0dadce89e0fa37 364 Pfam PF00529 HlyD membrane-fusion protein of T1SS 8 270 4.0E-7 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS03905 821659910d5527627e0dadce89e0fa37 364 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 29 353 6.4E-67 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS10005 0e987e4dfab37b4f3dff7229ac1eeeb0 207 Pfam PF01351 Ribonuclease HII 23 199 9.0E-35 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain hmeg3_RS10005 0e987e4dfab37b4f3dff7229ac1eeeb0 207 SUPERFAMILY SSF53098 20 205 5.61E-64 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS10005 0e987e4dfab37b4f3dff7229ac1eeeb0 207 Hamap MF_00052_B Ribonuclease HII [rnhB]. 21 200 34.728 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 hmeg3_RS10005 0e987e4dfab37b4f3dff7229ac1eeeb0 207 Gene3D G3DSA:3.30.420.10 3 207 5.0E-65 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS05805 b4558d6031086a5abb2e61d948179775 266 Gene3D G3DSA:3.40.190.10 30 123 3.5E-27 T 28-03-2018 hmeg3_RS05805 b4558d6031086a5abb2e61d948179775 266 PIRSF PIRSF002854 3 266 2.0E-107 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS05805 b4558d6031086a5abb2e61d948179775 266 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 28 266 2.1E-82 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS05805 b4558d6031086a5abb2e61d948179775 266 Pfam PF03180 NLPA lipoprotein 31 266 2.3E-97 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS05805 b4558d6031086a5abb2e61d948179775 266 Gene3D G3DSA:3.40.190.10 124 266 8.2E-55 T 28-03-2018 hmeg3_RS05805 b4558d6031086a5abb2e61d948179775 266 SUPERFAMILY SSF53850 30 266 1.13E-93 T 28-03-2018 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 140 151 - T 28-03-2018 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 97 119 3.4E-11 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 234 253 3.4E-11 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 202 220 3.4E-11 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 SUPERFAMILY SSF56534 28 280 3.53E-97 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 42 256 9.3E-46 T 28-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 Gene3D G3DSA:1.10.800.10 24 289 1.7E-92 T 28-03-2018 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 hmeg3_RS02925 b15a5e5d21d5948ba880cfc68e5368b8 292 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 34 277 1.6E-105 T 28-03-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 hmeg3_RS14975 693396b7b24885205268864a62ff7d25 146 Pfam PF03713 Domain of unknown function (DUF305) 14 134 4.0E-16 T 28-03-2018 IPR005183 Domain of unknown function DUF305 hmeg3_RS14975 693396b7b24885205268864a62ff7d25 146 Gene3D G3DSA:1.20.1260.10 3 138 3.2E-25 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS00795 254d97a62477df26c997e6c2c616ca1c 499 PIRSF PIRSF012702 1 498 5.0E-158 T 28-03-2018 IPR009197 Microcystin LR degradation protein MlrC hmeg3_RS00795 254d97a62477df26c997e6c2c616ca1c 499 Pfam PF07364 Metallopeptidase family M81 4 286 5.2E-95 T 28-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal hmeg3_RS00795 254d97a62477df26c997e6c2c616ca1c 499 Gene3D G3DSA:3.20.20.70 13 355 1.7E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS00795 254d97a62477df26c997e6c2c616ca1c 499 Pfam PF07171 MlrC C-terminus 300 482 1.0E-47 T 28-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 12 293 25.76 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 15 295 2.1E-79 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 Pfam PF01259 SAICAR synthetase 15 268 6.7E-102 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 Gene3D G3DSA:3.30.470.20 111 248 8.1E-54 T 28-03-2018 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 SUPERFAMILY SSF56104 4 294 3.6E-103 T 28-03-2018 hmeg3_RS20070 a76c90303555ddb840f2b81fc91740ee 298 Gene3D G3DSA:3.30.200.20 5 110 1.1E-33 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 1.5E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 1.5E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 1.5E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 1.5E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 1.5E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 1.5E-20 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82866 300 491 6.8E-34 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Gene3D G3DSA:3.30.2090.10 184 270 3.5E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Gene3D G3DSA:3.30.70.1430 556 700 2.8E-11 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Gene3D G3DSA:3.30.2090.10 707 794 3.3E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82714 188 269 6.41E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82693 558 639 7.85E-5 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82866 795 1015 2.22E-44 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82693 43 138 9.42E-15 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Gene3D G3DSA:3.30.70.1430 43 147 4.3E-22 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82714 708 791 1.7E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Gene3D G3DSA:1.20.1640.10 271 495 1.5E-29 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Gene3D G3DSA:1.20.1640.10 796 1013 1.6E-32 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82693 271 326 2.77E-13 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 SUPERFAMILY SSF82693 141 185 2.77E-13 T 28-03-2018 hmeg3_RS04155 ce4156276f877d2806fdacb04d1bb681 1033 Pfam PF00873 AcrB/AcrD/AcrF family 7 1009 2.2E-148 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16885 55adb795e938e0300df4953f48ee122d 179 SUPERFAMILY SSF50324 3 175 1.01E-69 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 hmeg3_RS16885 55adb795e938e0300df4953f48ee122d 179 Pfam PF00719 Inorganic pyrophosphatase 18 173 5.2E-55 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 hmeg3_RS16885 55adb795e938e0300df4953f48ee122d 179 Gene3D G3DSA:3.90.80.10 2 179 6.4E-56 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 hmeg3_RS16885 55adb795e938e0300df4953f48ee122d 179 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.808 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 hmeg3_RS16885 55adb795e938e0300df4953f48ee122d 179 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 hmeg3_RS14780 923c71e8610a9846a977940c1ba454fb 494 Gene3D G3DSA:2.40.50.100 208 422 5.9E-8 T 28-03-2018 hmeg3_RS14780 923c71e8610a9846a977940c1ba454fb 494 SUPERFAMILY SSF111369 129 327 1.57E-13 T 28-03-2018 hmeg3_RS14780 923c71e8610a9846a977940c1ba454fb 494 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 321 5.7E-70 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS14780 923c71e8610a9846a977940c1ba454fb 494 Pfam PF11604 Copper binding periplasmic protein CusF 427 490 4.3E-21 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF hmeg3_RS14780 923c71e8610a9846a977940c1ba454fb 494 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 204 395 2.9E-40 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS14780 923c71e8610a9846a977940c1ba454fb 494 Gene3D G3DSA:2.40.50.100 88 163 0.014 T 28-03-2018 hmeg3_RS21815 82a320c05f1ff049f27859af5aa53d48 269 Pfam PF01578 Cytochrome C assembly protein 64 262 1.1E-30 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 hmeg3_RS15600 0f08f3b27df26ab3135112f6ef3b6d70 443 PIRSF PIRSF002808 1 442 6.1E-48 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 hmeg3_RS15600 0f08f3b27df26ab3135112f6ef3b6d70 443 Pfam PF07690 Major Facilitator Superfamily 18 333 1.0E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS15600 0f08f3b27df26ab3135112f6ef3b6d70 443 SUPERFAMILY SSF103473 8 441 1.07E-83 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS15600 0f08f3b27df26ab3135112f6ef3b6d70 443 Gene3D G3DSA:1.20.1250.20 4 211 3.8E-36 T 28-03-2018 hmeg3_RS15600 0f08f3b27df26ab3135112f6ef3b6d70 443 Gene3D G3DSA:1.20.1250.20 225 442 1.3E-29 T 28-03-2018 hmeg3_RS15600 0f08f3b27df26ab3135112f6ef3b6d70 443 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 20 432 1.1E-149 T 28-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 hmeg3_RS00590 21805f50f19ebc4e939ba6037c266b9a 540 Gene3D G3DSA:3.90.226.10 9 278 2.3E-71 T 28-03-2018 hmeg3_RS00590 21805f50f19ebc4e939ba6037c266b9a 540 SUPERFAMILY SSF52096 22 274 1.24E-69 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS00590 21805f50f19ebc4e939ba6037c266b9a 540 Pfam PF01039 Carboxyl transferase domain 48 531 6.2E-151 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 hmeg3_RS00590 21805f50f19ebc4e939ba6037c266b9a 540 Gene3D G3DSA:3.90.226.10 279 536 1.3E-69 T 28-03-2018 hmeg3_RS00590 21805f50f19ebc4e939ba6037c266b9a 540 SUPERFAMILY SSF52096 242 522 1.93E-86 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 Gene3D G3DSA:3.40.50.300 223 372 1.1E-16 T 28-03-2018 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 Pfam PF01926 50S ribosome-binding GTPase 192 310 1.6E-18 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 3.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 212 3.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 Pfam PF16360 GTP-binding GTPase Middle Region 106 184 2.0E-27 T 28-03-2018 IPR032305 GTP-binding protein, middle domain hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 Pfam PF13167 GTP-binding GTPase N-terminal 17 104 1.6E-30 T 28-03-2018 IPR025121 GTPase HflX, N-terminal hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 Gene3D G3DSA:3.40.50.300 163 222 1.6E-11 T 28-03-2018 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 PIRSF PIRSF006809 1 368 3.4E-137 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 Hamap MF_00900 GTPase HflX [hflX]. 19 373 45.858 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 SUPERFAMILY SSF52540 190 354 1.18E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08900 f926588cd7bc4812f15f8a1ce5460e3b 375 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 351 4.2E-149 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 489 8.9E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 372 399 6.3E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 430 6.3E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 449 478 6.3E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 16 41 6.3E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 295 324 6.3E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 SUPERFAMILY SSF58104 242 522 3.01E-70 T 28-03-2018 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 191 3.3E-17 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 Gene3D G3DSA:1.10.287.950 33 328 1.9E-14 T 28-03-2018 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 Gene3D G3DSA:1.10.287.950 329 525 1.4E-47 T 28-03-2018 hmeg3_RS13490 0df978ab167d7794815ea7d33a370e56 542 SMART SM00283 274 521 4.3E-84 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 Pfam PF00990 Diguanylate cyclase, GGDEF domain 152 313 2.5E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 SMART SM00267 141 317 3.4E-64 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 SUPERFAMILY SSF55073 157 315 4.94E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 SUPERFAMILY SSF55785 13 125 5.06E-8 T 28-03-2018 IPR000014 PAS domain hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 148 315 6.6E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 Gene3D G3DSA:3.30.450.20 11 138 1.4E-8 T 28-03-2018 hmeg3_RS16590 52d7811d805db6d112a52ed41a914262 318 Gene3D G3DSA:3.30.70.270 142 318 2.3E-54 T 28-03-2018 hmeg3_RS20830 7350be87df916c4f70df39377f74b4b4 273 Gene3D G3DSA:3.90.850.10 1 265 2.4E-38 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS20830 7350be87df916c4f70df39377f74b4b4 273 SUPERFAMILY SSF56529 8 262 5.19E-47 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS09260 b0b44b1e68ece7519a13e96b9b4d3f2c 267 SUPERFAMILY SSF53474 2 261 1.32E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09260 b0b44b1e68ece7519a13e96b9b4d3f2c 267 Pfam PF12697 Alpha/beta hydrolase family 47 253 1.3E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS09260 b0b44b1e68ece7519a13e96b9b4d3f2c 267 Gene3D G3DSA:3.40.50.1820 2 263 7.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS15630 482fd39db7e4bbf558d0baf5c69bb112 345 Pfam PF00248 Aldo/keto reductase family 28 328 3.3E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS15630 482fd39db7e4bbf558d0baf5c69bb112 345 SUPERFAMILY SSF51430 13 331 7.6E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS15630 482fd39db7e4bbf558d0baf5c69bb112 345 Gene3D G3DSA:3.20.20.100 15 333 1.3E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 PRINTS PR00956 Flagellar motor switch protein FliN signature 305 318 2.5E-8 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 PRINTS PR00956 Flagellar motor switch protein FliN signature 318 333 2.5E-8 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 PRINTS PR00956 Flagellar motor switch protein FliN signature 272 288 2.5E-8 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 PRINTS PR00956 Flagellar motor switch protein FliN signature 289 305 2.5E-8 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 TIGRFAM TIGR02551 SpaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family 45 339 4.1E-31 T 28-03-2018 IPR013385 Type III secretion system apparatus protein YscQ/HrcQ/SpaO GO:0030254 hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 Gene3D G3DSA:2.30.330.10 260 351 5.1E-20 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 272 341 4.2E-16 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 SUPERFAMILY SSF101801 270 344 3.27E-16 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS15805 fcf529b1db8781d31054311fc82149bb 353 Gene3D G3DSA:2.30.330.10 157 242 0.17 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS23520 a0d014016b4388c9c00361c2a11ab864 385 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 220 233 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 hmeg3_RS23520 a0d014016b4388c9c00361c2a11ab864 385 Gene3D G3DSA:3.40.640.10 37 258 3.0E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS23520 a0d014016b4388c9c00361c2a11ab864 385 Pfam PF00155 Aminotransferase class I and II 16 375 3.6E-71 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS23520 a0d014016b4388c9c00361c2a11ab864 385 Gene3D G3DSA:3.90.1150.10 259 384 7.7E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS23520 a0d014016b4388c9c00361c2a11ab864 385 SUPERFAMILY SSF53383 6 382 1.9E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 Pfam PF01979 Amidohydrolase family 125 454 1.1E-79 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 ProSitePatterns PS00145 Urease active site. 317 333 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 Gene3D G3DSA:3.20.20.140 422 552 1.5E-45 T 28-03-2018 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 Gene3D G3DSA:3.20.20.140 143 421 2.0E-166 T 28-03-2018 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 SUPERFAMILY SSF51338 1 177 1.27E-62 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 Hamap MF_01953 Urease subunit alpha [ureC]. 2 566 57.249 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 8.1E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 8.1E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 8.1E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 8.1E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 119 6.2E-56 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 Gene3D G3DSA:2.30.40.10 64 142 2.5E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 SUPERFAMILY SSF51556 129 432 2.98E-200 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 SUPERFAMILY SSF51556 480 566 2.98E-200 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 ProSitePatterns PS01120 Urease nickel ligands signature. 127 140 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 566 5.7E-296 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00290 53f5b416d2df08ca588cfb07dfa5ce56 566 SUPERFAMILY SSF51338 426 477 2.01E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS05215 166980e086e8d102494b7be33168f1cc 325 SUPERFAMILY SSF51430 1 316 4.85E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS05215 166980e086e8d102494b7be33168f1cc 325 Gene3D G3DSA:3.20.20.100 1 322 5.4E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS05215 166980e086e8d102494b7be33168f1cc 325 Pfam PF00248 Aldo/keto reductase family 15 312 1.7E-53 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS08435 964f9d984f928ef5d5c9ca67474393bd 305 Gene3D G3DSA:3.40.50.170 1 200 2.6E-47 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS08435 964f9d984f928ef5d5c9ca67474393bd 305 Gene3D G3DSA:3.10.25.10 203 303 3.6E-16 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS08435 964f9d984f928ef5d5c9ca67474393bd 305 Pfam PF02911 Formyl transferase, C-terminal domain 202 291 6.4E-13 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS08435 964f9d984f928ef5d5c9ca67474393bd 305 SUPERFAMILY SSF50486 202 292 4.71E-15 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 hmeg3_RS08435 964f9d984f928ef5d5c9ca67474393bd 305 SUPERFAMILY SSF53328 1 202 2.49E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS08435 964f9d984f928ef5d5c9ca67474393bd 305 Pfam PF00551 Formyl transferase 24 176 7.6E-27 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 SMART SM00345 28 86 9.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 8.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 8.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 86 3.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 Gene3D G3DSA:1.20.120.530 91 242 8.2E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 Pfam PF07729 FCD domain 96 225 3.9E-17 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 SMART SM00895 96 226 2.3E-10 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 SUPERFAMILY SSF46785 22 90 3.53E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 Gene3D G3DSA:1.10.10.10 8 87 7.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24450 be0ce36efb663cfde01670b32c077d44 262 SUPERFAMILY SSF48008 92 231 2.12E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS10010 6d7c1f6d920284178fecf6066d87a6a0 263 SUPERFAMILY SSF55315 2 106 5.65E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like hmeg3_RS10010 6d7c1f6d920284178fecf6066d87a6a0 263 SUPERFAMILY SSF75217 115 260 1.18E-37 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS10010 6d7c1f6d920284178fecf6066d87a6a0 263 Pfam PF00588 SpoU rRNA Methylase family 117 252 9.4E-31 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 hmeg3_RS10010 6d7c1f6d920284178fecf6066d87a6a0 263 Gene3D G3DSA:3.40.1280.10 112 260 2.2E-38 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS10010 6d7c1f6d920284178fecf6066d87a6a0 263 Gene3D G3DSA:3.30.1330.30 1 106 2.4E-11 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 185 4.2E-21 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 SUPERFAMILY SSF58104 233 514 1.14E-73 T 28-03-2018 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 Gene3D G3DSA:1.10.287.950 232 317 1.4E-11 T 28-03-2018 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 SMART SM00304 213 265 1.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 4.3E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 42 1.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 190 210 1.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 Gene3D G3DSA:1.10.287.950 318 517 5.9E-47 T 28-03-2018 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 SMART SM00283 266 513 4.8E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08600 2c32da0bd91dfa10c29870cd8d1220cb 567 Gene3D G3DSA:1.20.120.30 26 187 4.0E-11 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS17130 bfed9237045f9b310de45cfab878790f 352 Pfam PF06804 NlpB/DapX lipoprotein 13 348 3.6E-54 T 28-03-2018 IPR010653 NlpB/DapX lipoprotein hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 SUPERFAMILY SSF54631 256 366 7.29E-17 T 28-03-2018 hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 Pfam PF00005 ABC transporter 23 168 8.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 18 366 6.5E-101 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 Gene3D G3DSA:3.10.580.10 247 375 1.2E-12 T 28-03-2018 hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 Pfam PF00571 CBS domain 260 306 3.9E-4 T 28-03-2018 IPR000644 CBS domain hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 Pfam PF00571 CBS domain 322 366 2.9E-4 T 28-03-2018 IPR000644 CBS domain hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 SMART SM00382 31 226 4.5E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 SMART SM00116 261 309 0.0024 T 28-03-2018 IPR000644 CBS domain hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 SMART SM00116 318 366 17.0 T 28-03-2018 IPR000644 CBS domain hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 SUPERFAMILY SSF52540 1 245 5.32E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14065 ab6afc11583aa1b9eebba5f08e37193e 377 Gene3D G3DSA:3.40.50.300 1 246 3.2E-69 T 28-03-2018 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 Pfam PF00202 Aminotransferase class-III 46 441 3.6E-74 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 292 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 PIRSF PIRSF000521 183 444 3.4E-30 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 PIRSF PIRSF000521 42 146 4.3E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 Gene3D G3DSA:3.90.1150.10 325 451 1.6E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 Gene3D G3DSA:3.40.640.10 69 324 1.5E-69 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS03810 70390ea7ec08b50e005f0106923acdac 451 SUPERFAMILY SSF53383 39 443 1.1E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS18320 eedeab0dabca429697bfa144f2b4ae8e 55 SUPERFAMILY SSF57829 1 53 7.32E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 hmeg3_RS18320 eedeab0dabca429697bfa144f2b4ae8e 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 4.9E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS18320 eedeab0dabca429697bfa144f2b4ae8e 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS18320 eedeab0dabca429697bfa144f2b4ae8e 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.556 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS18320 eedeab0dabca429697bfa144f2b4ae8e 55 Pfam PF00471 Ribosomal protein L33 8 53 4.7E-18 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 448 2.5E-27 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Gene3D G3DSA:2.40.110.10 157 272 5.2E-25 T 28-03-2018 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Gene3D G3DSA:1.20.140.10 277 461 6.6E-43 T 28-03-2018 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Gene3D G3DSA:1.10.540.10 12 156 1.6E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 33 1.1E-9 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 595 7.3E-32 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 270 5.4E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 SUPERFAMILY SSF47203 281 456 3.7E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 SUPERFAMILY SSF56645 33 293 4.19E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS16050 e451f6fb8be71b0e80cf082fea6199c6 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 35 155 3.6E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS20020 8245d39f4ce8eca0f299ee2afed6ec1b 191 Pfam PF04264 YceI-like domain 26 187 8.9E-37 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS20020 8245d39f4ce8eca0f299ee2afed6ec1b 191 SMART SM00867 25 188 1.2E-62 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS20020 8245d39f4ce8eca0f299ee2afed6ec1b 191 SUPERFAMILY SSF101874 22 190 2.35E-52 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS20020 8245d39f4ce8eca0f299ee2afed6ec1b 191 Gene3D G3DSA:2.40.128.110 24 191 2.6E-48 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 PIRSF PIRSF001362 1 428 7.1E-238 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 248 1.7E-107 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 ProSitePatterns PS00161 Isocitrate lyase signature. 186 191 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 SUPERFAMILY SSF51621 4 425 4.93E-158 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 Gene3D G3DSA:3.20.20.60 1 408 4.2E-151 T 28-03-2018 hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 Pfam PF00463 Isocitrate lyase family 12 248 7.3E-58 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 hmeg3_RS13350 88105f103eb13e19d8956b96f1bbff68 434 Pfam PF00463 Isocitrate lyase family 249 425 4.6E-44 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 Gene3D G3DSA:3.20.20.450 166 403 9.0E-61 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 Gene3D G3DSA:3.40.50.2300 2 165 2.2E-18 T 28-03-2018 hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 SMART SM00052 155 400 3.1E-37 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 Pfam PF00563 EAL domain 163 391 1.7E-51 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 Pfam PF00072 Response regulator receiver domain 9 129 2.3E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 SUPERFAMILY SSF52172 6 143 7.97E-19 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 SUPERFAMILY SSF141868 163 403 1.44E-56 T 28-03-2018 IPR001633 EAL domain hmeg3_RS15495 4b5a68ee5932ce19bc8e9167cfc15152 418 SMART SM00448 7 129 2.4E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS19270 4993c74baac7f47292c4b3421b5cdd09 210 Gene3D G3DSA:3.40.50.850 5 209 3.3E-44 T 28-03-2018 hmeg3_RS19270 4993c74baac7f47292c4b3421b5cdd09 210 SUPERFAMILY SSF52499 21 204 9.29E-49 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS19270 4993c74baac7f47292c4b3421b5cdd09 210 Pfam PF00857 Isochorismatase family 25 195 1.2E-38 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS21405 36c1eb04000db427c8c81b775c0e6085 263 Gene3D G3DSA:1.10.3720.10 54 255 2.4E-24 T 28-03-2018 hmeg3_RS21405 36c1eb04000db427c8c81b775c0e6085 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 251 2.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21405 36c1eb04000db427c8c81b775c0e6085 263 SUPERFAMILY SSF161098 55 242 4.97E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19185 4d614ba7a6cbcc0273eb14c0944de391 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 291 2.0E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19185 4d614ba7a6cbcc0273eb14c0944de391 316 Gene3D G3DSA:1.10.3470.10 28 300 2.9E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 Gene3D G3DSA:2.30.40.10 1 70 3.0E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 SUPERFAMILY SSF51556 61 123 4.43E-47 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 SUPERFAMILY SSF51556 203 492 4.43E-47 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 Pfam PF07969 Amidohydrolase family 50 532 2.5E-118 T 28-03-2018 IPR013108 Amidohydrolase 3 hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 Gene3D G3DSA:2.30.40.10 474 535 2.6E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 Gene3D G3DSA:3.20.20.140 71 473 9.7E-39 T 28-03-2018 hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 SUPERFAMILY SSF51338 1 62 1.63E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS18465 9ef8eeff24e37e9fa29250e48f23010a 619 SUPERFAMILY SSF51338 491 540 1.63E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 Gene3D G3DSA:3.90.1150.10 317 406 1.5E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 Gene3D G3DSA:3.90.1150.10 9 88 3.9E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 SUPERFAMILY SSF53383 9 406 8.64E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 Gene3D G3DSA:3.40.640.10 89 316 1.7E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 Pfam PF00155 Aminotransferase class I and II 37 402 2.9E-84 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 PRINTS PR00799 Aspartate aminotransferase signature 283 308 2.2E-39 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 PRINTS PR00799 Aspartate aminotransferase signature 351 369 2.2E-39 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 PRINTS PR00799 Aspartate aminotransferase signature 185 204 2.2E-39 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 PRINTS PR00799 Aspartate aminotransferase signature 216 228 2.2E-39 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 hmeg3_RS08060 ef0fb94104c30974e8ed4a0a835748bf 406 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 253 266 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 hmeg3_RS04565 0e2bc347b2cfae44ad766de2c2c74c96 281 Pfam PF11249 Protein of unknown function (DUF3047) 65 261 5.8E-62 T 28-03-2018 IPR021409 Protein of unknown function DUF3047 hmeg3_RS15370 c45b60e2ff44ff1b6a9f133744d14934 151 Pfam PF01638 HxlR-like helix-turn-helix 20 105 2.5E-18 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS15370 c45b60e2ff44ff1b6a9f133744d14934 151 Gene3D G3DSA:1.10.10.10 2 151 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15370 c45b60e2ff44ff1b6a9f133744d14934 151 SUPERFAMILY SSF46785 6 144 9.92E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 SUPERFAMILY SSF53850 87 291 1.09E-47 T 28-03-2018 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 SUPERFAMILY SSF46785 6 87 6.23E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 Gene3D G3DSA:1.10.10.10 3 84 8.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 Gene3D G3DSA:3.40.190.10 85 175 1.6E-21 T 28-03-2018 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 9.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 Gene3D G3DSA:3.40.190.10 176 259 2.0E-24 T 28-03-2018 hmeg3_RS18500 7e015e9f971310c6d2e45121f088da98 300 Pfam PF03466 LysR substrate binding domain 87 288 1.8E-46 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS03925 f8430bfb2555d650bf51b380c3c8f29a 586 SUPERFAMILY SSF51905 10 348 3.27E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03925 f8430bfb2555d650bf51b380c3c8f29a 586 SUPERFAMILY SSF51905 517 577 3.27E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03925 f8430bfb2555d650bf51b380c3c8f29a 586 SUPERFAMILY SSF54373 431 499 1.06E-10 T 28-03-2018 hmeg3_RS03925 f8430bfb2555d650bf51b380c3c8f29a 586 Pfam PF00732 GMC oxidoreductase 200 348 1.2E-6 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS03925 f8430bfb2555d650bf51b380c3c8f29a 586 Pfam PF05199 GMC oxidoreductase 444 571 5.6E-23 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS03925 f8430bfb2555d650bf51b380c3c8f29a 586 Gene3D G3DSA:3.50.50.60 6 583 1.3E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS14890 3f8d62917eeb33b7293739c4c86b4b78 233 Pfam PF01584 CheW-like domain 87 225 9.7E-21 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14890 3f8d62917eeb33b7293739c4c86b4b78 233 SUPERFAMILY SSF50341 76 227 1.83E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS14890 3f8d62917eeb33b7293739c4c86b4b78 233 Gene3D G3DSA:2.30.30.40 173 219 1.0E-5 T 28-03-2018 hmeg3_RS14890 3f8d62917eeb33b7293739c4c86b4b78 233 Gene3D G3DSA:2.40.50.180 103 172 1.2E-12 T 28-03-2018 hmeg3_RS14890 3f8d62917eeb33b7293739c4c86b4b78 233 SMART SM00260 82 225 3.0E-9 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 Gene3D G3DSA:1.10.10.10 2 88 2.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 7.0E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 SUPERFAMILY SSF46785 8 115 4.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 Gene3D G3DSA:3.40.190.10 93 180 3.9E-15 T 28-03-2018 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 SUPERFAMILY SSF53850 94 301 1.71E-45 T 28-03-2018 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 Gene3D G3DSA:3.40.190.10 181 270 5.5E-24 T 28-03-2018 hmeg3_RS23580 b9953474cd8bdec722771286b37d7114 303 Pfam PF03466 LysR substrate binding domain 94 298 4.4E-43 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 73 8.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 73 83 8.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 83 94 8.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 Gene3D G3DSA:3.40.190.10 132 222 1.0E-16 T 28-03-2018 hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 SUPERFAMILY SSF53850 133 338 1.45E-30 T 28-03-2018 hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 SUPERFAMILY SSF46785 45 148 9.72E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 Pfam PF03466 LysR substrate binding domain 132 338 6.6E-27 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 Gene3D G3DSA:3.40.190.10 223 309 8.3E-14 T 28-03-2018 hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 Gene3D G3DSA:1.10.10.10 40 127 4.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04560 3436cc506cadd7c41db47f142772b482 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 47 106 7.7E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23345 e0c1eed39c1c4b9991a35ff443e375c6 348 Gene3D G3DSA:3.40.190.10 35 138 1.6E-8 T 28-03-2018 hmeg3_RS23345 e0c1eed39c1c4b9991a35ff443e375c6 348 Pfam PF09084 NMT1/THI5 like 62 259 2.3E-17 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS23345 e0c1eed39c1c4b9991a35ff443e375c6 348 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 40 344 4.9E-101 T 28-03-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 hmeg3_RS23345 e0c1eed39c1c4b9991a35ff443e375c6 348 SUPERFAMILY SSF53850 38 260 3.53E-43 T 28-03-2018 hmeg3_RS23345 e0c1eed39c1c4b9991a35ff443e375c6 348 Gene3D G3DSA:3.40.190.10 139 347 1.3E-29 T 28-03-2018 hmeg3_RS23345 e0c1eed39c1c4b9991a35ff443e375c6 348 SMART SM00062 39 253 3.7E-4 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 Pfam PF00990 Diguanylate cyclase, GGDEF domain 347 508 4.2E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 Gene3D G3DSA:3.30.450.20 42 176 7.4E-15 T 28-03-2018 hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 343 512 1.0E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 Gene3D G3DSA:3.30.450.20 177 295 4.0E-11 T 28-03-2018 hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 SUPERFAMILY SSF55073 352 513 6.51E-45 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 Gene3D G3DSA:3.30.70.270 340 518 7.8E-52 T 28-03-2018 hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 SMART SM00267 336 512 7.6E-60 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS03980 2156005210e3d15213ff45d61986e8b9 521 Pfam PF02743 Cache domain 52 240 9.9E-16 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS06920 856d2c7043861c7488e2abbace2bec0c 331 Gene3D G3DSA:3.90.1200.10 114 326 1.3E-24 T 28-03-2018 hmeg3_RS06920 856d2c7043861c7488e2abbace2bec0c 331 Hamap MF_01497 Stress response kinase A [srkA]. 6 324 48.31 T 28-03-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 hmeg3_RS06920 856d2c7043861c7488e2abbace2bec0c 331 Gene3D G3DSA:3.30.200.20 7 110 2.6E-18 T 28-03-2018 hmeg3_RS06920 856d2c7043861c7488e2abbace2bec0c 331 SUPERFAMILY SSF56112 8 330 7.87E-83 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS06920 856d2c7043861c7488e2abbace2bec0c 331 Pfam PF01636 Phosphotransferase enzyme family 38 264 6.1E-36 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 264 1.1E-96 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 84 2.6E-40 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 Pfam PF00303 Thymidylate synthase 3 264 7.1E-127 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 39.982 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 1.7E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 1.7E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.7E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 1.7E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 1.7E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 SUPERFAMILY SSF55831 1 264 6.94E-130 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS17700 39aedbce8fa1761f178644e65ddab9ad 264 Gene3D G3DSA:3.30.572.10 1 264 3.9E-133 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 hmeg3_RS16530 52594dede5925187740246215bd52733 294 Gene3D G3DSA:2.120.10.30 21 294 3.6E-38 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like hmeg3_RS16530 52594dede5925187740246215bd52733 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 17 34 4.7E-33 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS16530 52594dede5925187740246215bd52733 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 195 212 4.7E-33 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS16530 52594dede5925187740246215bd52733 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 157 177 4.7E-33 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS16530 52594dede5925187740246215bd52733 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 4.7E-33 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS16530 52594dede5925187740246215bd52733 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 4.7E-33 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS16530 52594dede5925187740246215bd52733 294 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 16 255 6.4E-77 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region hmeg3_RS16530 52594dede5925187740246215bd52733 294 SUPERFAMILY SSF63829 6 284 4.09E-67 T 28-03-2018 hmeg3_RS12570 111c0f7d34a8e55471e6ad8809adba0d 248 Pfam PF01925 Sulfite exporter TauE/SafE 9 236 2.3E-25 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS02525 7784abd562470c86b9e02d4a7a709a24 154 SUPERFAMILY SSF51182 40 143 2.41E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS02525 7784abd562470c86b9e02d4a7a709a24 154 Gene3D G3DSA:2.60.120.10 13 153 2.7E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS02525 7784abd562470c86b9e02d4a7a709a24 154 Pfam PF07883 Cupin domain 74 138 7.9E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS20660 d6811cb82c3745635fb33be7e231e62d 178 SUPERFAMILY SSF69118 1 176 2.22E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS20660 d6811cb82c3745635fb33be7e231e62d 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 109 8.5E-9 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS20660 d6811cb82c3745635fb33be7e231e62d 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 99 3.2E-10 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS20660 d6811cb82c3745635fb33be7e231e62d 178 Gene3D G3DSA:1.20.1290.10 45 173 4.2E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS20660 d6811cb82c3745635fb33be7e231e62d 178 Gene3D G3DSA:1.20.5.810 11 44 3.9E-5 T 28-03-2018 hmeg3_RS09220 8727f799a6bfab3dcd547bf66179173d 564 Pfam PF02272 DHHA1 domain 320 446 4.5E-23 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 hmeg3_RS09220 8727f799a6bfab3dcd547bf66179173d 564 SUPERFAMILY SSF64182 48 460 9.03E-116 T 28-03-2018 hmeg3_RS09220 8727f799a6bfab3dcd547bf66179173d 564 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 23 559 1.3E-146 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 hmeg3_RS09220 8727f799a6bfab3dcd547bf66179173d 564 Gene3D G3DSA:3.90.1640.10 53 244 1.6E-21 T 28-03-2018 hmeg3_RS09220 8727f799a6bfab3dcd547bf66179173d 564 Pfam PF01368 DHH family 75 179 5.4E-9 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 52 2.0E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 Gene3D G3DSA:3.40.190.10 82 166 7.9E-15 T 28-03-2018 hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 Gene3D G3DSA:1.10.10.10 1 75 5.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 SUPERFAMILY SSF46785 2 102 2.52E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 SUPERFAMILY SSF53850 79 283 6.52E-38 T 28-03-2018 hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 Gene3D G3DSA:3.40.190.10 167 253 5.2E-17 T 28-03-2018 hmeg3_RS12620 701e08c0c73671cc01e18bd42121b31b 296 Pfam PF03466 LysR substrate binding domain 78 282 1.9E-35 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS06240 b3dbeb742e11aa81c09349918aacb8ee 224 Pfam PF01965 DJ-1/PfpI family 29 219 2.2E-15 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS06240 b3dbeb742e11aa81c09349918aacb8ee 224 SUPERFAMILY SSF52317 4 221 1.2E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS06240 b3dbeb742e11aa81c09349918aacb8ee 224 Gene3D G3DSA:3.40.50.880 1 223 2.6E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS11555 bb88d3e85f848eb73ba59912b9b0b972 299 Pfam PF08668 HDOD domain 16 213 2.2E-39 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS11555 bb88d3e85f848eb73ba59912b9b0b972 299 Gene3D G3DSA:1.10.3210.10 3 282 6.1E-29 T 28-03-2018 hmeg3_RS11555 bb88d3e85f848eb73ba59912b9b0b972 299 SUPERFAMILY SSF109604 10 280 5.34E-47 T 28-03-2018 hmeg3_RS19025 17fc59c666d6f7f549512be5b4c26fb5 323 Gene3D G3DSA:3.40.50.2300 30 147 1.1E-22 T 28-03-2018 hmeg3_RS19025 17fc59c666d6f7f549512be5b4c26fb5 323 Gene3D G3DSA:3.40.50.2300 148 309 2.5E-34 T 28-03-2018 hmeg3_RS19025 17fc59c666d6f7f549512be5b4c26fb5 323 Pfam PF13407 Periplasmic binding protein domain 36 297 1.0E-47 T 28-03-2018 IPR025997 Periplasmic binding protein hmeg3_RS19025 17fc59c666d6f7f549512be5b4c26fb5 323 SUPERFAMILY SSF53822 30 303 9.9E-74 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS22780 42328c26c3ed10affff58b4cf8153f84 120 SUPERFAMILY SSF53137 3 118 3.05E-46 T 28-03-2018 hmeg3_RS22780 42328c26c3ed10affff58b4cf8153f84 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 120 23.886 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22780 42328c26c3ed10affff58b4cf8153f84 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 120 1.7E-34 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22780 42328c26c3ed10affff58b4cf8153f84 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 120 9.9E-34 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22780 42328c26c3ed10affff58b4cf8153f84 120 Gene3D G3DSA:3.30.420.100 1 120 3.9E-32 T 28-03-2018 hmeg3_RS00040 a151f1a84f360232bf9106a1de2684af 182 Pfam PF00419 Fimbrial protein 25 182 1.3E-9 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS00040 a151f1a84f360232bf9106a1de2684af 182 Gene3D G3DSA:2.60.40.1090 22 182 1.8E-26 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS00040 a151f1a84f360232bf9106a1de2684af 182 SUPERFAMILY SSF49401 33 182 5.97E-20 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS20035 47aa2a6a5254c0d0d0c28d4e9ba0bab2 179 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 3.4E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS20035 47aa2a6a5254c0d0d0c28d4e9ba0bab2 179 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 162 36.484 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS20035 47aa2a6a5254c0d0d0c28d4e9ba0bab2 179 Pfam PF01625 Peptide methionine sulfoxide reductase 7 157 1.6E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS20035 47aa2a6a5254c0d0d0c28d4e9ba0bab2 179 Gene3D G3DSA:3.30.1060.10 1 171 9.1E-72 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS20035 47aa2a6a5254c0d0d0c28d4e9ba0bab2 179 SUPERFAMILY SSF55068 3 169 1.16E-72 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS09450 99783cbd2df301d3bc077be36fff206a 400 SUPERFAMILY SSF46626 108 220 1.89E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS09450 99783cbd2df301d3bc077be36fff206a 400 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 130 216 8.7E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS09450 99783cbd2df301d3bc077be36fff206a 400 Gene3D G3DSA:1.10.760.10 116 245 4.6E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS04260 d5d809d612fa367ce73a76cf391e227e 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.6E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04260 d5d809d612fa367ce73a76cf391e227e 303 Gene3D G3DSA:3.40.190.10 136 266 1.2E-7 T 28-03-2018 hmeg3_RS04260 d5d809d612fa367ce73a76cf391e227e 303 Pfam PF03466 LysR substrate binding domain 95 296 1.3E-14 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04260 d5d809d612fa367ce73a76cf391e227e 303 SUPERFAMILY SSF53850 87 295 3.8E-28 T 28-03-2018 hmeg3_RS04260 d5d809d612fa367ce73a76cf391e227e 303 Gene3D G3DSA:1.10.10.10 1 86 4.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04260 d5d809d612fa367ce73a76cf391e227e 303 SUPERFAMILY SSF46785 5 86 9.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 SUPERFAMILY SSF90123 178 492 9.81E-76 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 Pfam PF00664 ABC transporter transmembrane region 190 464 3.2E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 SMART SM00382 537 723 2.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 Pfam PF00005 ABC transporter 529 677 7.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 ProSitePatterns PS00211 ABC transporters family signature. 649 663 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 Gene3D G3DSA:1.20.1560.10 164 500 2.2E-67 T 28-03-2018 hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 SUPERFAMILY SSF52540 502 747 7.67E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09910 1521586eacc208362dd97e6c7c3bcc84 769 Gene3D G3DSA:3.40.50.300 501 753 6.1E-81 T 28-03-2018 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 Gene3D G3DSA:3.30.920.10 1 111 9.5E-31 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 SMART SM01219 1 109 3.6E-47 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 107 1.9E-35 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 Pfam PF01491 Frataxin-like domain 1 104 1.1E-27 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 SUPERFAMILY SSF55387 1 108 5.06E-33 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 Hamap MF_00142 Protein CyaY [cyaY]. 1 108 25.403 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS22460 f058370cdff8bb593fd4e0a59fb5f9b3 111 ProSitePatterns PS01344 Frataxin family signature. 53 67 - T 28-03-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 SUPERFAMILY SSF144083 255 317 2.75E-20 T 28-03-2018 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 3 320 9.9E-72 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 Gene3D G3DSA:1.20.58.340 135 252 4.1E-11 T 28-03-2018 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 Pfam PF01544 CorA-like Mg2+ transporter protein 29 316 1.9E-54 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 SUPERFAMILY SSF143865 1 259 2.62E-38 T 28-03-2018 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 Gene3D G3DSA:1.20.58.340 253 320 4.2E-19 T 28-03-2018 hmeg3_RS21700 b89823a18ce5d00c04c2e10c89767636 321 Gene3D G3DSA:3.30.460.20 1 130 2.0E-14 T 28-03-2018 hmeg3_RS11970 169104ec05599aaa1913239ea0f209a9 990 Pfam PF13700 Domain of unknown function (DUF4158) 4 165 6.6E-31 T 28-03-2018 IPR025296 Domain of unknown function DUF4158 hmeg3_RS11970 169104ec05599aaa1913239ea0f209a9 990 Pfam PF01526 Tn3 transposase DDE domain 585 971 1.5E-151 T 28-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 SUPERFAMILY SSF51735 4 259 2.12E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 Gene3D G3DSA:3.40.50.720 1 183 3.3E-56 T 28-03-2018 hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 Gene3D G3DSA:3.40.50.720 184 256 6.4E-7 T 28-03-2018 hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 9.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 6 260 1.3E-95 T 28-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 hmeg3_RS06125 633d74dfe407dc3624e44f5e71d31675 260 Pfam PF00106 short chain dehydrogenase 6 198 4.1E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 Gene3D G3DSA:3.40.1670.10 330 466 2.1E-51 T 28-03-2018 hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 SUPERFAMILY SSF143968 330 493 2.62E-66 T 28-03-2018 hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 Gene3D G3DSA:1.20.5.570 467 494 9.2E-18 T 28-03-2018 hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 462 2.2E-160 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 494 72.081 T 28-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 SUPERFAMILY SSF50475 3 329 5.1E-117 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS05640 5ee6d83dbfb45ee5e4eca538bb2ba315 494 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 438 1.1E-166 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 SUPERFAMILY SSF53850 90 269 3.26E-16 T 28-03-2018 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 Gene3D G3DSA:1.10.10.10 1 83 2.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 Gene3D G3DSA:3.40.190.10 88 184 0.0014 T 28-03-2018 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 Pfam PF03466 LysR substrate binding domain 90 304 1.7E-14 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 SUPERFAMILY SSF46785 1 85 3.63E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 Gene3D G3DSA:3.40.190.10 188 271 1.9E-8 T 28-03-2018 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04660 92f93926cc33f458734d24bcd8629b43 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07365 26550606be0ee14b7d689e332ff62b9d 138 SUPERFAMILY SSF54593 1 133 1.13E-36 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS07365 26550606be0ee14b7d689e332ff62b9d 138 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 130 1.1E-11 T 28-03-2018 IPR028973 PhnB-like hmeg3_RS07365 26550606be0ee14b7d689e332ff62b9d 138 Gene3D G3DSA:3.10.180.10 1 138 2.7E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 SUPERFAMILY SSF52540 470 690 2.01E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 Gene3D G3DSA:3.90.70.10 1 142 9.0E-38 T 28-03-2018 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 ProSitePatterns PS00211 ABC transporters family signature. 614 628 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 Pfam PF00664 ABC transporter transmembrane region 165 430 1.6E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 Gene3D G3DSA:3.40.50.300 464 693 1.8E-62 T 28-03-2018 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 Pfam PF03412 Peptidase C39 family 2 134 6.3E-33 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 Gene3D G3DSA:1.20.1560.10 146 463 8.5E-39 T 28-03-2018 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 SMART SM00382 502 686 1.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 Pfam PF00005 ABC transporter 493 642 4.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10240 f6734bd1c920411ec4fa7b02c0f3d0db 699 SUPERFAMILY SSF90123 148 460 3.14E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS12110 508cb109b56134b09548355c42179af2 300 Gene3D G3DSA:3.90.25.10 160 297 5.6E-16 T 28-03-2018 hmeg3_RS12110 508cb109b56134b09548355c42179af2 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 213 1.2E-13 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS12110 508cb109b56134b09548355c42179af2 300 Gene3D G3DSA:3.40.50.720 1 159 1.9E-20 T 28-03-2018 hmeg3_RS12110 508cb109b56134b09548355c42179af2 300 SUPERFAMILY SSF51735 1 289 3.98E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19295 fd56bcbd612013ed0db80be6eeebec35 472 Pfam PF01425 Amidase 26 454 5.5E-92 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS19295 fd56bcbd612013ed0db80be6eeebec35 472 Gene3D G3DSA:3.90.1300.10 3 471 5.5E-123 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS19295 fd56bcbd612013ed0db80be6eeebec35 472 SUPERFAMILY SSF75304 4 471 9.29E-121 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS19295 fd56bcbd612013ed0db80be6eeebec35 472 ProSitePatterns PS00571 Amidases signature. 154 185 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 hmeg3_RS18025 357eecc8336e8f37ff052ce12205ecdb 1258 Gene3D G3DSA:3.30.1330.60 1066 1255 2.3E-17 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18025 357eecc8336e8f37ff052ce12205ecdb 1258 Pfam PF05359 Domain of Unknown Function (DUF748) 620 774 4.0E-32 T 28-03-2018 IPR008023 Protein of unknown function DUF748 hmeg3_RS18025 357eecc8336e8f37ff052ce12205ecdb 1258 Pfam PF05359 Domain of Unknown Function (DUF748) 151 297 7.5E-21 T 28-03-2018 IPR008023 Protein of unknown function DUF748 hmeg3_RS18025 357eecc8336e8f37ff052ce12205ecdb 1258 Pfam PF05359 Domain of Unknown Function (DUF748) 392 533 3.1E-15 T 28-03-2018 IPR008023 Protein of unknown function DUF748 hmeg3_RS18025 357eecc8336e8f37ff052ce12205ecdb 1258 Pfam PF05359 Domain of Unknown Function (DUF748) 861 1006 2.6E-36 T 28-03-2018 IPR008023 Protein of unknown function DUF748 hmeg3_RS18890 2e4efc7b0bc3cdfae8f3efdceedff755 455 Gene3D G3DSA:3.20.20.30 1 454 1.4E-106 T 28-03-2018 hmeg3_RS18890 2e4efc7b0bc3cdfae8f3efdceedff755 455 Pfam PF00296 Luciferase-like monooxygenase 30 391 6.4E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS18890 2e4efc7b0bc3cdfae8f3efdceedff755 455 SUPERFAMILY SSF51679 1 437 1.7E-122 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS18890 2e4efc7b0bc3cdfae8f3efdceedff755 455 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 7 433 4.9E-162 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS18890 2e4efc7b0bc3cdfae8f3efdceedff755 455 PIRSF PIRSF000337 2 448 3.3E-131 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS13405 64b282dc75bd4e31ea9f74d5d5118e2f 739 Pfam PF04632 Fusaric acid resistance protein family 24 711 1.2E-195 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 hmeg3_RS00200 24bf5425c70a234c0689b4399b520109 173 SUPERFAMILY SSF49401 41 172 3.43E-16 T 28-03-2018 IPR008966 Adhesion domain hmeg3_RS00200 24bf5425c70a234c0689b4399b520109 173 Pfam PF00419 Fimbrial protein 41 173 1.1E-10 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS00200 24bf5425c70a234c0689b4399b520109 173 Gene3D G3DSA:2.60.40.1090 39 173 8.4E-19 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 hmeg3_RS17605 fc30410bbf94a91447d82dce86c7cdb1 139 SUPERFAMILY SSF102400 1 136 1.96E-40 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 hmeg3_RS17605 fc30410bbf94a91447d82dce86c7cdb1 139 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 133 1.8E-39 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 hmeg3_RS17605 fc30410bbf94a91447d82dce86c7cdb1 139 Gene3D G3DSA:3.40.50.10110 1 139 5.7E-44 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 hmeg3_RS19325 82d26d50166c4bc5d26d3dd9d7077a80 269 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19325 82d26d50166c4bc5d26d3dd9d7077a80 269 SMART SM00382 49 242 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19325 82d26d50166c4bc5d26d3dd9d7077a80 269 Pfam PF00005 ABC transporter 41 195 5.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19325 82d26d50166c4bc5d26d3dd9d7077a80 269 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 244 265 1.2E-7 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS19325 82d26d50166c4bc5d26d3dd9d7077a80 269 SUPERFAMILY SSF52540 24 266 3.66E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19325 82d26d50166c4bc5d26d3dd9d7077a80 269 Gene3D G3DSA:3.40.50.300 5 268 6.4E-52 T 28-03-2018 hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PIRSF PIRSF002869 1 514 3.2E-149 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 Pfam PF03023 MviN-like protein 28 473 1.4E-137 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 33 52 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 133 157 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 157 178 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 52 68 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 413 430 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 361 380 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 PRINTS PR01806 Virulence factor MviN signature 263 289 3.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 3 507 6.9E-142 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS06600 a559166e2ec158dd582c7719ed05ba04 516 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 471 19.279 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ hmeg3_RS07255 e267abe828f4cca0ec9b49a163cc11ce 282 SUPERFAMILY SSF111364 37 282 1.57E-36 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 hmeg3_RS07255 e267abe828f4cca0ec9b49a163cc11ce 282 Gene3D G3DSA:2.40.230.20 30 276 6.5E-64 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 Gene3D G3DSA:3.40.50.720 109 215 8.1E-23 T 28-03-2018 hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 Pfam PF02719 Polysaccharide biosynthesis protein 262 570 2.3E-124 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 Gene3D G3DSA:3.40.50.720 216 268 0.058 T 28-03-2018 hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 Gene3D G3DSA:3.40.50.720 269 608 7.0E-59 T 28-03-2018 hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 Pfam PF13727 CoA-binding domain 43 217 2.7E-8 T 28-03-2018 hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 SUPERFAMILY SSF51735 259 549 5.57E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21185 f29bdfd902e1439df12a3282d70f7939 629 SUPERFAMILY SSF53335 93 320 6.31E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 Pfam PF08447 PAS fold 32 114 1.1E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 SMART SM00086 80 121 4.3E-6 T 28-03-2018 IPR001610 PAC motif hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 SUPERFAMILY SSF58104 241 522 2.62E-70 T 28-03-2018 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 Gene3D G3DSA:1.10.287.950 330 525 1.1E-45 T 28-03-2018 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 Gene3D G3DSA:1.10.287.950 217 329 7.4E-17 T 28-03-2018 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 SUPERFAMILY SSF55785 21 114 1.34E-25 T 28-03-2018 IPR000014 PAS domain hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 489 1.4E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 Pfam PF00672 HAMP domain 222 269 3.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 SMART SM00304 221 273 9.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 SMART SM00283 274 521 1.8E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 Gene3D G3DSA:3.40.50.10600 13 128 1.6E-25 T 28-03-2018 hmeg3_RS11505 d833586dedd4c151742e9fb00a4c9d6f 549 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 114 2.7E-14 T 28-03-2018 IPR000014 PAS domain hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 Gene3D G3DSA:3.40.640.10 37 272 3.3E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 PIRSF PIRSF000412 1 415 6.6E-167 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 52.41 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 Gene3D G3DSA:3.90.1150.10 273 413 3.1E-62 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 Pfam PF00464 Serine hydroxymethyltransferase 9 383 1.3E-174 T 28-03-2018 hmeg3_RS18080 1a22161c99afa3cd42d388802828334d 415 SUPERFAMILY SSF53383 7 413 9.35E-181 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS09945 28d892bc82b5a51061f835066dce50d5 238 Gene3D G3DSA:3.40.1160.10 1 238 1.4E-44 T 28-03-2018 hmeg3_RS09945 28d892bc82b5a51061f835066dce50d5 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 43.981 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 hmeg3_RS09945 28d892bc82b5a51061f835066dce50d5 238 PIRSF PIRSF005650 1 238 4.1E-90 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 hmeg3_RS09945 28d892bc82b5a51061f835066dce50d5 238 SUPERFAMILY SSF53633 4 237 1.02E-70 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS09945 28d892bc82b5a51061f835066dce50d5 238 Pfam PF00696 Amino acid kinase family 7 216 5.3E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS09945 28d892bc82b5a51061f835066dce50d5 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 1.9E-99 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 hmeg3_RS00845 caee0e93ca57ebb4b94a6aa7f170f2b7 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 141 201 2.9E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS00845 caee0e93ca57ebb4b94a6aa7f170f2b7 219 SUPERFAMILY SSF56784 16 212 1.16E-36 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS00845 caee0e93ca57ebb4b94a6aa7f170f2b7 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 200 7.7E-14 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS00845 caee0e93ca57ebb4b94a6aa7f170f2b7 219 Gene3D G3DSA:3.40.50.1000 3 219 1.2E-22 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS19265 ee2fcf7e5f169e4e750713bbcc75a73b 350 SUPERFAMILY SSF144052 140 340 2.88E-17 T 28-03-2018 hmeg3_RS23725 15b02e3c75e597049425a585c537b38a 291 Gene3D G3DSA:3.40.190.10 164 240 2.9E-8 T 28-03-2018 hmeg3_RS23725 15b02e3c75e597049425a585c537b38a 291 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 75 274 6.2E-20 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23725 15b02e3c75e597049425a585c537b38a 291 Gene3D G3DSA:3.40.190.10 53 163 4.7E-14 T 28-03-2018 hmeg3_RS23725 15b02e3c75e597049425a585c537b38a 291 SUPERFAMILY SSF53850 67 278 2.51E-30 T 28-03-2018 hmeg3_RS23725 15b02e3c75e597049425a585c537b38a 291 SMART SM00062 62 283 1.1E-25 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS00095 afe5357e97370a8a596fa613dc54fe6d 336 SUPERFAMILY SSF53850 46 265 6.59E-31 T 28-03-2018 hmeg3_RS00095 afe5357e97370a8a596fa613dc54fe6d 336 Gene3D G3DSA:3.40.190.10 35 142 3.5E-11 T 28-03-2018 hmeg3_RS00095 afe5357e97370a8a596fa613dc54fe6d 336 Pfam PF09084 NMT1/THI5 like 50 260 3.5E-34 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS00095 afe5357e97370a8a596fa613dc54fe6d 336 Gene3D G3DSA:3.40.190.10 143 336 1.5E-27 T 28-03-2018 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 Gene3D G3DSA:3.10.580.10 507 579 1.4E-7 T 28-03-2018 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 Gene3D G3DSA:3.10.580.10 431 506 2.2E-8 T 28-03-2018 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 PRINTS PR00762 Chloride channel signature 369 385 2.9E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 PRINTS PR00762 Chloride channel signature 171 190 2.9E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 PRINTS PR00762 Chloride channel signature 387 406 2.9E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 PRINTS PR00762 Chloride channel signature 334 354 2.9E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 PRINTS PR00762 Chloride channel signature 120 139 2.9E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 Pfam PF00571 CBS domain 458 503 0.0029 T 28-03-2018 IPR000644 CBS domain hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 Pfam PF00571 CBS domain 515 571 2.7E-5 T 28-03-2018 IPR000644 CBS domain hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 SUPERFAMILY SSF81340 10 435 6.54E-109 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 Gene3D G3DSA:1.10.3080.10 8 430 9.5E-94 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 SUPERFAMILY SSF54631 449 572 1.01E-16 T 28-03-2018 hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 SMART SM00116 455 503 2.3 T 28-03-2018 IPR000644 CBS domain hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 SMART SM00116 527 573 8.4 T 28-03-2018 IPR000644 CBS domain hmeg3_RS13325 8608b21bff9bc359bd97aa3883f61a4e 580 Pfam PF00654 Voltage gated chloride channel 79 419 2.2E-88 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 Gene3D G3DSA:3.90.226.10 16 208 1.5E-46 T 28-03-2018 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 126 139 - T 28-03-2018 IPR033135 ClpP, histidine active site hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 1.6E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 PRINTS PR00127 Clp protease catalytic subunit P signature 33 48 1.6E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 PRINTS PR00127 Clp protease catalytic subunit P signature 125 144 1.6E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 1.6E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 1.6E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 SUPERFAMILY SSF52096 25 206 1.75E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 17 207 44.573 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 16 206 2.0E-105 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 hmeg3_RS10450 5e9baec0cfed2c271de9abce7ad8c3af 208 Pfam PF00574 Clp protease 27 206 1.2E-88 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 43 150 3.9E-13 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 277 4.1E-17 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Pfam PF08447 PAS fold 50 136 4.9E-20 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SUPERFAMILY SSF55073 287 443 1.33E-52 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SMART SM00267 271 443 1.1E-72 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Pfam PF13426 PAS domain 166 270 1.5E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SUPERFAMILY SSF55785 30 146 1.26E-21 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Gene3D G3DSA:3.30.450.20 148 286 6.2E-33 T 28-03-2018 hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SMART SM00052 453 698 6.2E-130 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Gene3D G3DSA:3.20.20.450 448 710 2.6E-106 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 279 442 1.4E-48 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SUPERFAMILY SSF55785 140 265 5.76E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Gene3D G3DSA:3.30.70.270 287 447 3.3E-63 T 28-03-2018 hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SMART SM00086 101 143 8.6E-6 T 28-03-2018 IPR001610 PAC motif hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SMART SM00086 229 271 0.001 T 28-03-2018 IPR001610 PAC motif hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Pfam PF00990 Diguanylate cyclase, GGDEF domain 282 439 2.8E-54 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Pfam PF00563 EAL domain 460 693 6.3E-75 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SUPERFAMILY SSF141868 461 703 5.1E-93 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SMART SM00091 155 222 2.9E-4 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 SMART SM00091 24 95 9.1E-5 T 28-03-2018 IPR000014 PAS domain hmeg3_RS05565 e6a98ccadeadff59f94a5b7294535c12 712 Gene3D G3DSA:3.30.450.20 12 147 1.0E-24 T 28-03-2018 hmeg3_RS16465 5221a2f07277dc102bf7d463eca66484 127 Gene3D G3DSA:3.30.429.10 1 127 2.5E-30 T 28-03-2018 hmeg3_RS16465 5221a2f07277dc102bf7d463eca66484 127 Pfam PF14552 Tautomerase enzyme 38 119 2.4E-33 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 hmeg3_RS16465 5221a2f07277dc102bf7d463eca66484 127 SUPERFAMILY SSF55331 2 125 2.92E-43 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PIRSF PIRSF002583 3 637 3.2E-216 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 SUPERFAMILY SSF54211 236 495 1.14E-96 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 184 1.9E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 Hamap MF_00505 Chaperone protein HtpG [htpG]. 4 632 33.01 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 7 27 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 28 50 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 122 144 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 174 191 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 77 94 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 95 112 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 PRINTS PR00775 90kDa heat shock protein signature 192 210 9.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 SMART SM00387 29 186 5.3E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 Pfam PF00183 Hsp90 protein 217 631 5.2E-133 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 Gene3D G3DSA:3.30.565.10 500 589 0.0033 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 SUPERFAMILY SSF55874 7 218 2.88E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 SUPERFAMILY SSF110942 521 632 2.35E-35 T 28-03-2018 hmeg3_RS07580 bb1c5d42d11baf7f25e6964beed0f746 637 Gene3D G3DSA:3.30.565.10 1 229 1.7E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 Pfam PF13481 AAA domain 82 221 2.4E-14 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 7.7E-194 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 SUPERFAMILY SSF54211 254 268 1.74E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 SUPERFAMILY SSF54211 302 455 1.74E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 SMART SM00382 90 243 9.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 Gene3D G3DSA:3.40.50.300 72 282 2.4E-44 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 360 452 5.8E-5 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 SUPERFAMILY SSF52540 69 289 5.41E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 82 110 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 212 240 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 123 140 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 173 197 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 247 273 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 321 344 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 PRINTS PR01874 DNA repair protein radA signature 10 34 3.9E-93 T 28-03-2018 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 43.728 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 hmeg3_RS09805 d44d282596d772c82b1c4179b156fcfd 458 Gene3D G3DSA:3.30.230.10 284 454 2.1E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 SUPERFAMILY SSF160996 204 358 5.1E-12 T 28-03-2018 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 17 411 2.4E-88 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 Pfam PF03486 HI0933-like protein 16 411 1.5E-110 T 28-03-2018 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 37 418 9.6E-166 T 28-03-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 5.2E-8 T 28-03-2018 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 5.2E-8 T 28-03-2018 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 SUPERFAMILY SSF51905 17 205 8.55E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 SUPERFAMILY SSF51905 357 417 8.55E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02655 839167c57b84486cb5bd0f27d8db76c7 428 Gene3D G3DSA:3.50.50.60 17 413 1.8E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 2.0E-38 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 2.0E-65 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 SUPERFAMILY SSF55200 84 173 6.93E-34 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 Gene3D G3DSA:3.10.20.80 4 80 1.0E-27 T 28-03-2018 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 SUPERFAMILY SSF54364 7 79 3.4E-26 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 8.8E-27 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 29.421 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 hmeg3_RS07755 a51e63e89e4b4b8361307b197ffade67 173 Gene3D G3DSA:3.30.110.10 81 173 3.7E-36 T 28-03-2018 hmeg3_RS14445 7f55cde6ab314224aba05869a107b6a5 286 Pfam PF00563 EAL domain 39 261 1.1E-14 T 28-03-2018 IPR001633 EAL domain hmeg3_RS14445 7f55cde6ab314224aba05869a107b6a5 286 SMART SM00052 13 269 0.001 T 28-03-2018 IPR001633 EAL domain hmeg3_RS14445 7f55cde6ab314224aba05869a107b6a5 286 SUPERFAMILY SSF141868 38 267 4.32E-18 T 28-03-2018 IPR001633 EAL domain hmeg3_RS14445 7f55cde6ab314224aba05869a107b6a5 286 Gene3D G3DSA:3.20.20.450 31 281 7.3E-20 T 28-03-2018 IPR001633 EAL domain hmeg3_RS22655 4332382c2a2ec9c088104f7d9969a543 343 SMART SM00062 44 266 0.0015 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS22655 4332382c2a2ec9c088104f7d9969a543 343 SUPERFAMILY SSF53850 33 257 9.94E-43 T 28-03-2018 hmeg3_RS22655 4332382c2a2ec9c088104f7d9969a543 343 Gene3D G3DSA:3.40.190.10 130 336 2.6E-32 T 28-03-2018 hmeg3_RS22655 4332382c2a2ec9c088104f7d9969a543 343 Pfam PF13379 NMT1-like family 50 259 1.5E-17 T 28-03-2018 hmeg3_RS22655 4332382c2a2ec9c088104f7d9969a543 343 Gene3D G3DSA:3.40.190.10 30 127 1.5E-7 T 28-03-2018 hmeg3_RS12150 ddc7843d62b5955b41908e94398a347a 253 Gene3D G3DSA:3.40.50.300 11 251 9.1E-70 T 28-03-2018 hmeg3_RS12150 ddc7843d62b5955b41908e94398a347a 253 PIRSF PIRSF039085 12 253 2.5E-101 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS12150 ddc7843d62b5955b41908e94398a347a 253 SUPERFAMILY SSF52540 15 247 8.76E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12150 ddc7843d62b5955b41908e94398a347a 253 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS12150 ddc7843d62b5955b41908e94398a347a 253 SMART SM00382 40 227 6.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS12150 ddc7843d62b5955b41908e94398a347a 253 Pfam PF00005 ABC transporter 31 179 9.3E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 Gene3D G3DSA:3.40.190.80 150 265 7.8E-33 T 28-03-2018 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 SUPERFAMILY SSF56655 2 264 9.56E-85 T 28-03-2018 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 Pfam PF00459 Inositol monophosphatase family 5 253 4.8E-70 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 Gene3D G3DSA:3.30.540.10 3 149 4.4E-50 T 28-03-2018 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 2.1E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 2.1E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 2.1E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 2.1E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.1E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 2.1E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 160 186 7.1E-29 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 202 214 7.1E-29 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 108 127 7.1E-29 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 19 41 7.1E-29 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 hmeg3_RS14020 3a069fed2bfb8052b01560bb3f846ed7 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site hmeg3_RS22855 d161b5bf4b9575d1ab88bb2292663a63 206 Pfam PF00573 Ribosomal protein L4/L1 family 18 203 3.4E-60 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22855 d161b5bf4b9575d1ab88bb2292663a63 206 Gene3D G3DSA:3.40.1370.10 1 144 1.1E-47 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22855 d161b5bf4b9575d1ab88bb2292663a63 206 Gene3D G3DSA:3.40.1370.10 145 204 1.3E-9 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22855 d161b5bf4b9575d1ab88bb2292663a63 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 31.317 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22855 d161b5bf4b9575d1ab88bb2292663a63 206 SUPERFAMILY SSF52166 1 205 8.37E-69 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22855 d161b5bf4b9575d1ab88bb2292663a63 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 2.0E-68 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 Gene3D G3DSA:3.90.180.10 1 133 1.1E-37 T 28-03-2018 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 Gene3D G3DSA:3.40.50.720 134 309 1.1E-30 T 28-03-2018 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 Pfam PF00107 Zinc-binding dehydrogenase 152 257 9.4E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.6E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 SUPERFAMILY SSF51735 113 273 5.36E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 SMART SM00829 11 323 2.9E-34 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS18785 d3894f40235e8beb584739a3423f921b 325 SUPERFAMILY SSF50129 2 145 5.17E-39 T 28-03-2018 IPR011032 GroES-like hmeg3_RS16405 ed8e026e69348fa25809f4aca3a22e67 201 Pfam PF02632 BioY family 42 189 5.1E-34 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 hmeg3_RS16405 ed8e026e69348fa25809f4aca3a22e67 201 PIRSF PIRSF016661 4 198 1.5E-41 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 hmeg3_RS15135 4670eca602d92ae18244eb1776af1892 404 SUPERFAMILY SSF53822 30 397 1.5E-83 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS15135 4670eca602d92ae18244eb1776af1892 404 Gene3D G3DSA:3.40.50.2300 29 160 6.7E-9 T 28-03-2018 hmeg3_RS15135 4670eca602d92ae18244eb1776af1892 404 Pfam PF13458 Periplasmic binding protein 30 369 1.3E-84 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS15135 4670eca602d92ae18244eb1776af1892 404 Gene3D G3DSA:3.40.50.2300 161 311 3.0E-33 T 28-03-2018 hmeg3_RS09655 ec52a888576c0b3acb9a9e31cf1afc8a 974 Gene3D G3DSA:3.40.50.1460 750 970 2.8E-17 T 28-03-2018 hmeg3_RS09655 ec52a888576c0b3acb9a9e31cf1afc8a 974 Gene3D G3DSA:1.25.40.10 24 544 4.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS09655 ec52a888576c0b3acb9a9e31cf1afc8a 974 Pfam PF12770 CHAT domain 698 969 3.9E-41 T 28-03-2018 IPR024983 CHAT domain hmeg3_RS03820 856ea5b204f53aee4500d338fbdfc03b 221 Gene3D G3DSA:3.40.50.1000 85 215 2.1E-13 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS03820 856ea5b204f53aee4500d338fbdfc03b 221 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 6 199 8.3E-49 T 28-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 hmeg3_RS03820 856ea5b204f53aee4500d338fbdfc03b 221 SUPERFAMILY SSF56784 4 219 1.26E-37 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS03820 856ea5b204f53aee4500d338fbdfc03b 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 92 186 1.6E-7 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS03820 856ea5b204f53aee4500d338fbdfc03b 221 Gene3D G3DSA:1.10.150.240 22 84 0.0015 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 hmeg3_RS03820 856ea5b204f53aee4500d338fbdfc03b 221 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 8 181 2.6E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS16610 c8c54a381ddbcc2c500ec209e66d73c4 270 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 17 260 2.7E-37 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS16610 c8c54a381ddbcc2c500ec209e66d73c4 270 Pfam PF02654 Cobalamin-5-phosphate synthase 21 258 1.9E-54 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS16610 c8c54a381ddbcc2c500ec209e66d73c4 270 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 270 52.51 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 hmeg3_RS08345 2c612b0bd1ae365aa2628b0824cf1e7f 111 Gene3D G3DSA:1.20.58.380 4 89 7.8E-25 T 28-03-2018 hmeg3_RS08345 2c612b0bd1ae365aa2628b0824cf1e7f 111 Pfam PF05400 Flagellar protein FliT 20 105 7.9E-21 T 28-03-2018 IPR008622 Flagellar protein FliT hmeg3_RS18750 33964326f2d9fda08e472a195dfe9a4c 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 249 1.4E-26 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS18750 33964326f2d9fda08e472a195dfe9a4c 260 SUPERFAMILY SSF53850 26 250 1.92E-35 T 28-03-2018 hmeg3_RS18750 33964326f2d9fda08e472a195dfe9a4c 260 Gene3D G3DSA:3.40.190.10 136 252 4.0E-7 T 28-03-2018 hmeg3_RS18750 33964326f2d9fda08e472a195dfe9a4c 260 SMART SM00062 27 253 6.0E-9 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS18750 33964326f2d9fda08e472a195dfe9a4c 260 Gene3D G3DSA:3.40.190.10 16 135 3.9E-16 T 28-03-2018 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 SUPERFAMILY SSF55874 13 208 5.24E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 217 333 9.4E-38 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 SMART SM00853 445 588 4.4E-54 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 Pfam PF08676 MutL C terminal dimerisation domain 441 588 1.9E-47 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 13 314 7.7E-95 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 104 110 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 129 2.6E-12 T 28-03-2018 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 SMART SM01340 216 334 8.0E-57 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 12 628 28.007 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 SUPERFAMILY SSF118116 440 630 1.01E-58 T 28-03-2018 hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 Gene3D G3DSA:3.30.565.10 7 208 6.6E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 Gene3D G3DSA:3.30.230.10 221 333 2.6E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS19775 c1177e7f335da2b32486d252cef5e114 632 SUPERFAMILY SSF54211 199 334 3.19E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 212 1.4E-51 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 Gene3D G3DSA:3.40.50.1000 1 32 3.2E-4 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 1.2E-33 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 Gene3D G3DSA:1.10.150.240 33 77 2.1E-12 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 186 3.2E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 182 2.4E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 SUPERFAMILY SSF56784 7 217 3.36E-58 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS18020 8c8514cc684e497b6232124255456883 219 Gene3D G3DSA:3.40.50.1000 78 219 6.1E-32 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS14370 d7ec462b70ec3676e5300dccb6bfdcc0 335 SUPERFAMILY SSF51735 9 320 1.97E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14370 d7ec462b70ec3676e5300dccb6bfdcc0 335 Gene3D G3DSA:3.40.50.720 5 321 9.5E-34 T 28-03-2018 hmeg3_RS14370 d7ec462b70ec3676e5300dccb6bfdcc0 335 Pfam PF13460 NAD(P)H-binding 15 121 2.8E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 Gene3D G3DSA:3.30.450.40 84 259 9.0E-37 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 SMART SM00346 9 100 1.8E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 Pfam PF01614 Bacterial transcriptional regulator 146 252 9.3E-17 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 Gene3D G3DSA:1.10.10.10 9 71 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 SUPERFAMILY SSF55781 68 255 1.7E-39 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 SUPERFAMILY SSF46785 11 81 9.26E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24515 89f182776c1daa87bff97ef477e7d215 275 Pfam PF09339 IclR helix-turn-helix domain 12 62 7.0E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS16305 3f52658132d082eb69b2b826c8a9c392 330 SUPERFAMILY SSF56235 3 155 2.03E-97 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS16305 3f52658132d082eb69b2b826c8a9c392 330 SUPERFAMILY SSF56235 194 328 2.03E-97 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS16305 3f52658132d082eb69b2b826c8a9c392 330 Gene3D G3DSA:3.60.20.30 197 330 9.6E-48 T 28-03-2018 hmeg3_RS16305 3f52658132d082eb69b2b826c8a9c392 330 Pfam PF01112 Asparaginase 4 329 3.1E-116 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 hmeg3_RS18440 c5371b0182efc5dfb976c7e471294a5f 307 Gene3D G3DSA:3.40.250.10 192 307 8.8E-20 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS18440 c5371b0182efc5dfb976c7e471294a5f 307 Pfam PF00581 Rhodanese-like domain 210 300 2.0E-11 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS18440 c5371b0182efc5dfb976c7e471294a5f 307 Pfam PF09335 SNARE associated Golgi protein 29 155 3.8E-14 T 28-03-2018 IPR032816 SNARE associated Golgi protein hmeg3_RS18440 c5371b0182efc5dfb976c7e471294a5f 307 SMART SM00450 207 304 2.6E-10 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS18440 c5371b0182efc5dfb976c7e471294a5f 307 SUPERFAMILY SSF52821 184 306 2.88E-24 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS17180 10852ab45cf7699d465e37634e92dc73 413 PIRSF PIRSF001434 1 413 4.4E-117 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS17180 10852ab45cf7699d465e37634e92dc73 413 Gene3D G3DSA:3.90.1150.10 295 413 3.0E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS17180 10852ab45cf7699d465e37634e92dc73 413 Gene3D G3DSA:3.40.640.10 4 294 4.7E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS17180 10852ab45cf7699d465e37634e92dc73 413 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 411 6.5E-105 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS17180 10852ab45cf7699d465e37634e92dc73 413 SUPERFAMILY SSF53383 8 412 2.63E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 SUPERFAMILY SSF58104 233 514 7.59E-73 T 28-03-2018 hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 184 2.1E-23 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 481 1.1E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 SMART SM00304 213 265 2.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 SMART SM00283 266 513 3.9E-83 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 Gene3D G3DSA:1.10.287.950 311 517 7.6E-49 T 28-03-2018 hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 Pfam PF00672 HAMP domain 213 261 3.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05275 45570ba907d96b4feb71ef350771ee68 554 Gene3D G3DSA:1.20.120.30 25 185 4.8E-21 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 7 480 2.4E-138 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 72 97 7.3E-5 T 28-03-2018 hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 312 324 7.3E-5 T 28-03-2018 hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 425 444 7.3E-5 T 28-03-2018 hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 7.3E-5 T 28-03-2018 hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 4 482 18.56 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 hmeg3_RS13720 6ab0c9fbe899c8c498579d9cd7c6dd2f 503 Pfam PF00361 Proton-conducting membrane transporter 130 429 1.5E-75 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 270 34.386 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 248 4.6E-31 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 Gene3D G3DSA:3.20.20.70 1 272 1.4E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 SMART SM00934 17 260 1.0E-43 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 SUPERFAMILY SSF51366 3 270 1.92E-75 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 249 1.1E-73 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS07180 c9b123f702739b6197aaeb2d5b0fd8aa 272 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 hmeg3_RS05350 3ba3ddba9be730405588a6aee409e4dc 143 Pfam PF07681 DoxX 20 103 2.6E-16 T 28-03-2018 IPR032808 DoxX family hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 SMART SM00283 267 514 3.1E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 Pfam PF08269 Cache domain 32 183 6.9E-35 T 28-03-2018 IPR004010 Double Cache domain 2 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 SUPERFAMILY SSF58104 237 515 1.16E-70 T 28-03-2018 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 2.2E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 2.2E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 2.2E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 2.2E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 482 9.1E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 Gene3D G3DSA:1.10.287.950 210 318 4.2E-11 T 28-03-2018 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 SMART SM01049 33 127 1.0E-28 T 28-03-2018 IPR033480 Single Cache domain 2 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 Gene3D G3DSA:1.10.287.950 319 515 4.3E-46 T 28-03-2018 hmeg3_RS05220 05fab06383908b995f7d22dacd2fd028 515 Gene3D G3DSA:3.30.450.20 25 191 6.5E-43 T 28-03-2018 hmeg3_RS22765 09b8613ea4d659e64da751a590b7aa0c 143 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22765 09b8613ea4d659e64da751a590b7aa0c 143 Gene3D G3DSA:3.100.10.10 42 143 3.0E-24 T 28-03-2018 hmeg3_RS22765 09b8613ea4d659e64da751a590b7aa0c 143 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 4.1E-46 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22765 09b8613ea4d659e64da751a590b7aa0c 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 9.6E-31 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P hmeg3_RS22765 09b8613ea4d659e64da751a590b7aa0c 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 19.562 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 hmeg3_RS22765 09b8613ea4d659e64da751a590b7aa0c 143 SUPERFAMILY SSF52080 4 142 2.88E-45 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 14 454 2.8E-168 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 SMART SM00729 149 378 1.6E-47 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 SUPERFAMILY SSF102114 126 383 3.01E-48 T 28-03-2018 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 Pfam PF04055 Radical SAM superfamily 155 336 4.7E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 13 457 60.754 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 14 455 2.5E-99 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 153 173 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 Gene3D G3DSA:3.80.30.20 147 392 6.1E-44 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 Gene3D G3DSA:2.40.50.140 393 458 1.2E-19 T 28-03-2018 hmeg3_RS08655 16ffa38a4770ab526b308bfabefd3ed4 458 Pfam PF00919 Uncharacterized protein family UPF0004 14 93 2.9E-19 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 Gene3D G3DSA:3.90.1150.10 384 508 1.4E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 Pfam PF00155 Aminotransferase class I and II 183 499 3.9E-30 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 SMART SM00345 39 98 2.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 Gene3D G3DSA:1.10.10.10 26 100 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 SUPERFAMILY SSF46785 28 105 2.84E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 Gene3D G3DSA:3.40.640.10 179 383 3.8E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 SUPERFAMILY SSF53383 161 502 1.93E-69 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS07615 37a4fb9e1ac6725f12b0d449bef31984 512 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 98 1.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05940 3c966150180c0571149235377037e076 324 Pfam PF01965 DJ-1/PfpI family 3 176 3.9E-23 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS05940 3c966150180c0571149235377037e076 324 Gene3D G3DSA:3.40.50.880 1 207 7.4E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS05940 3c966150180c0571149235377037e076 324 Gene3D G3DSA:1.10.10.60 208 270 4.9E-11 T 28-03-2018 hmeg3_RS05940 3c966150180c0571149235377037e076 324 SUPERFAMILY SSF46689 266 316 8.96E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05940 3c966150180c0571149235377037e076 324 Gene3D G3DSA:1.10.10.60 271 324 1.8E-10 T 28-03-2018 hmeg3_RS05940 3c966150180c0571149235377037e076 324 Pfam PF12833 Helix-turn-helix domain 236 314 1.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS05940 3c966150180c0571149235377037e076 324 SUPERFAMILY SSF46689 214 260 1.03E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS05940 3c966150180c0571149235377037e076 324 SMART SM00342 230 313 2.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS05940 3c966150180c0571149235377037e076 324 SUPERFAMILY SSF52317 1 196 4.37E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 1.4E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 426 5.0E-208 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS14825 5e8bea222a1b30a3eee5a01ee8dfc243 427 Pfam PF02040 Arsenical pump membrane protein 4 423 3.7E-156 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 7 500 37.82 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 187 491 4.1E-125 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 SUPERFAMILY SSF52949 11 185 6.47E-36 T 28-03-2018 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 PRINTS PR00481 Cytosol aminopeptidase signature 322 343 8.3E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 PRINTS PR00481 Cytosol aminopeptidase signature 285 306 8.3E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 PRINTS PR00481 Cytosol aminopeptidase signature 344 364 8.3E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 PRINTS PR00481 Cytosol aminopeptidase signature 263 280 8.3E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 PRINTS PR00481 Cytosol aminopeptidase signature 372 387 8.3E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 SUPERFAMILY SSF53187 181 500 6.28E-122 T 28-03-2018 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 Gene3D G3DSA:3.40.220.10 1 161 2.7E-31 T 28-03-2018 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 348 355 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 Gene3D G3DSA:3.40.630.10 171 505 3.4E-136 T 28-03-2018 hmeg3_RS15345 deefbfd75645eaa76d70aa8f82577e98 507 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 23 149 1.8E-27 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 hmeg3_RS13765 d01c08ee2a704e04f8550e2b4f882371 163 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 16 162 2.5E-49 T 28-03-2018 hmeg3_RS13765 d01c08ee2a704e04f8550e2b4f882371 163 SUPERFAMILY SSF52833 8 162 2.12E-51 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS13765 d01c08ee2a704e04f8550e2b4f882371 163 PIRSF PIRSF000216 3 163 1.0E-56 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13765 d01c08ee2a704e04f8550e2b4f882371 163 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 118 136 - T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13765 d01c08ee2a704e04f8550e2b4f882371 163 Gene3D G3DSA:3.40.30.10 79 163 4.0E-12 T 28-03-2018 hmeg3_RS13765 d01c08ee2a704e04f8550e2b4f882371 163 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 14 162 2.7E-59 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS20120 54ff6e4a14ef523573b99d1b24807088 204 Pfam PF11161 Protein of unknown function (DUF2946) 1 195 8.0E-67 T 28-03-2018 IPR021332 Protein of unknown function DUF2944 hmeg3_RS18910 49f68e88cd0be9481dacf26dd3afc795 327 Pfam PF01501 Glycosyl transferase family 8 20 264 8.3E-48 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 hmeg3_RS18910 49f68e88cd0be9481dacf26dd3afc795 327 Gene3D G3DSA:3.90.550.10 19 289 9.8E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS18910 49f68e88cd0be9481dacf26dd3afc795 327 SUPERFAMILY SSF53448 20 287 7.59E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS18910 49f68e88cd0be9481dacf26dd3afc795 327 Pfam PF08437 Glycosyl transferase family 8 C-terminal 272 322 2.2E-14 T 28-03-2018 IPR013645 Glycosyl transferase, family 8, C-terminal GO:0008918|GO:0009103 hmeg3_RS15685 ebf03f8f849eed9a4540268eb89bacf9 60 SUPERFAMILY SSF54786 1 60 1.45E-17 T 28-03-2018 hmeg3_RS15685 ebf03f8f849eed9a4540268eb89bacf9 60 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 59 7.1E-20 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 hmeg3_RS15685 ebf03f8f849eed9a4540268eb89bacf9 60 Gene3D G3DSA:3.30.920.30 1 59 8.8E-22 T 28-03-2018 hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 Gene3D G3DSA:3.40.50.2300 22 174 1.3E-27 T 28-03-2018 hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 173 342 9.8E-55 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 SMART SM00267 166 342 1.3E-64 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 SUPERFAMILY SSF52172 23 155 1.42E-27 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 SMART SM00448 25 139 1.2E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 Pfam PF00072 Response regulator receiver domain 27 139 8.0E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 Pfam PF00990 Diguanylate cyclase, GGDEF domain 178 338 9.6E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 Gene3D G3DSA:3.30.70.270 175 344 3.9E-52 T 28-03-2018 hmeg3_RS14875 52bc80aab4553839f3ae4bdb805238c3 344 SUPERFAMILY SSF55073 182 341 7.45E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS12245 48ae5b665366a1588c02602c424839f6 171 Gene3D G3DSA:3.40.140.10 11 171 1.6E-23 T 28-03-2018 hmeg3_RS12245 48ae5b665366a1588c02602c424839f6 171 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 19 114 5.3E-13 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain hmeg3_RS12245 48ae5b665366a1588c02602c424839f6 171 SUPERFAMILY SSF53927 16 123 3.95E-29 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 SUPERFAMILY SSF48179 209 306 1.87E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 433 6.4E-132 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 301 1.2E-37 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 SMART SM00984 325 437 6.3E-49 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 436 1.0E-29 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 Gene3D G3DSA:1.20.5.100 210 232 2.0E-14 T 28-03-2018 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 PIRSF PIRSF000124 1 452 1.4E-148 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 Gene3D G3DSA:3.40.50.720 1 206 4.7E-62 T 28-03-2018 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 184 2.3E-66 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 PIRSF PIRSF500134 1 455 4.4E-186 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 SUPERFAMILY SSF51735 1 200 3.33E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 SUPERFAMILY SSF52413 310 447 7.72E-39 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 hmeg3_RS17945 908950613a5003406047585bfb7f09dc 458 Gene3D G3DSA:3.40.50.720 233 449 2.8E-71 T 28-03-2018 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 1.8E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 SMART SM00878 336 441 9.1E-64 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 Gene3D G3DSA:3.30.1490.20 124 210 4.0E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 Gene3D G3DSA:3.30.470.20 211 444 7.6E-96 T 28-03-2018 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 5.4E-224 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 2.5E-81 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 SUPERFAMILY SSF56059 83 347 2.47E-71 T 28-03-2018 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.9E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 SUPERFAMILY SSF52440 1 113 2.09E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 Gene3D G3DSA:3.40.50.20 1 123 5.0E-54 T 28-03-2018 hmeg3_RS21760 5a363117acdd5653e4f47cc9fc960449 459 SUPERFAMILY SSF51246 331 443 4.5E-42 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 205 388 2.9E-10 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 92 115 - T 28-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 4.7E-30 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 85 105 4.7E-30 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 106 126 4.7E-30 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 192 214 4.7E-30 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 154 180 4.7E-30 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 Gene3D G3DSA:2.102.10.10 47 160 1.6E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 Gene3D G3DSA:3.90.380.10 161 426 5.6E-43 T 28-03-2018 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 Pfam PF00355 Rieske [2Fe-2S] domain 50 132 1.2E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 SUPERFAMILY SSF55961 180 418 2.28E-46 T 28-03-2018 hmeg3_RS01305 249c367d60e8c39b031d4de37bee5800 426 SUPERFAMILY SSF50022 17 168 5.76E-44 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS11395 a6a1f4747565997a08c7fc88f4759f45 122 SUPERFAMILY SSF52172 2 120 8.68E-29 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS11395 a6a1f4747565997a08c7fc88f4759f45 122 Pfam PF00072 Response regulator receiver domain 4 114 1.4E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11395 a6a1f4747565997a08c7fc88f4759f45 122 SMART SM00448 2 116 7.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS11395 a6a1f4747565997a08c7fc88f4759f45 122 Gene3D G3DSA:3.40.50.2300 1 122 1.6E-28 T 28-03-2018 hmeg3_RS17125 9e0fd3c9242bc8542d11542ef75dd371 261 Gene3D G3DSA:3.60.15.10 10 253 1.5E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS17125 9e0fd3c9242bc8542d11542ef75dd371 261 SMART SM00849 11 195 9.6E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS17125 9e0fd3c9242bc8542d11542ef75dd371 261 SUPERFAMILY SSF56281 2 249 1.83E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS17125 9e0fd3c9242bc8542d11542ef75dd371 261 Pfam PF12706 Beta-lactamase superfamily domain 28 212 3.8E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 SMART SM00304 210 262 3.9E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 Gene3D G3DSA:1.10.287.950 208 314 2.0E-11 T 28-03-2018 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 Gene3D G3DSA:1.10.287.950 315 514 4.7E-48 T 28-03-2018 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 161 4.9E-18 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 4.9E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 SUPERFAMILY SSF58104 230 515 5.1E-76 T 28-03-2018 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 Gene3D G3DSA:1.20.120.30 22 184 3.0E-10 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 Pfam PF00672 HAMP domain 210 253 6.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 478 1.7E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00185 1cde7e99885b5dbb94645dcf25928379 571 SMART SM00283 263 510 2.2E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04140 790810f89d9a7c4fbd267795d9a0fc05 258 SUPERFAMILY SSF56524 52 257 1.31E-62 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS04140 790810f89d9a7c4fbd267795d9a0fc05 258 Gene3D G3DSA:3.90.420.10 51 257 2.8E-56 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS04140 790810f89d9a7c4fbd267795d9a0fc05 258 Pfam PF00174 Oxidoreductase molybdopterin binding domain 104 247 2.1E-32 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 352 3.6E-90 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 Gene3D G3DSA:3.40.640.10 39 274 1.6E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 354 55.442 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 210 219 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 SUPERFAMILY SSF53383 5 353 1.49E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 Gene3D G3DSA:3.90.1150.10 275 355 1.5E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS00500 c80717ae5092239607e4ee0a64df9854 355 Pfam PF00155 Aminotransferase class I and II 25 350 1.7E-55 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS10420 0ac83d042c0aa95f45d03312baff5723 269 Pfam PF00494 Squalene/phytoene synthase 5 256 2.0E-64 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 hmeg3_RS10420 0ac83d042c0aa95f45d03312baff5723 269 SUPERFAMILY SSF48576 4 269 1.58E-72 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS10420 0ac83d042c0aa95f45d03312baff5723 269 Gene3D G3DSA:1.10.600.10 1 269 2.4E-75 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS10420 0ac83d042c0aa95f45d03312baff5723 269 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 1 267 5.7E-113 T 28-03-2018 IPR017827 Squalene synthase HpnC hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 263 35.794 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 3.0E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 3.0E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 PRINTS PR00474 Glutamate 5-kinase family signature 213 233 3.0E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 3.0E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 3.0E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 PIRSF PIRSF000729 4 372 1.1E-128 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 Gene3D G3DSA:3.40.1160.10 1 269 4.4E-63 T 28-03-2018 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 Gene3D G3DSA:2.30.130.10 279 371 3.1E-27 T 28-03-2018 IPR002478 PUA domain GO:0003723 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 Pfam PF01472 PUA domain 281 355 1.7E-20 T 28-03-2018 IPR002478 PUA domain GO:0003723 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 Pfam PF00696 Amino acid kinase family 9 237 5.1E-44 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 370 5.0E-129 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 SMART SM00359 281 364 4.2E-15 T 28-03-2018 IPR002478 PUA domain GO:0003723 hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 SUPERFAMILY SSF88697 281 371 1.16E-22 T 28-03-2018 IPR015947 PUA-like domain hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 SUPERFAMILY SSF53633 9 259 4.32E-69 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase hmeg3_RS21870 83d4384d2f19eade41e2f31acb4699b9 372 ProSitePatterns PS00902 Glutamate 5-kinase signature. 211 228 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 hmeg3_RS00370 bb76de043a86b6e3fa4135ce72aa8a48 438 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 436 4.9E-162 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS00370 bb76de043a86b6e3fa4135ce72aa8a48 438 Gene3D G3DSA:3.20.20.30 3 438 3.7E-100 T 28-03-2018 hmeg3_RS00370 bb76de043a86b6e3fa4135ce72aa8a48 438 SUPERFAMILY SSF51679 4 437 4.45E-120 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS00370 bb76de043a86b6e3fa4135ce72aa8a48 438 Pfam PF00296 Luciferase-like monooxygenase 24 394 1.2E-61 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS00370 bb76de043a86b6e3fa4135ce72aa8a48 438 PIRSF PIRSF000337 4 438 3.8E-157 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 hmeg3_RS19795 9f519c28bab052f2c31d9d7cdcd6a10d 200 SUPERFAMILY SSF52499 3 199 7.33E-47 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS19795 9f519c28bab052f2c31d9d7cdcd6a10d 200 Gene3D G3DSA:3.40.50.850 2 200 5.5E-42 T 28-03-2018 hmeg3_RS19795 9f519c28bab052f2c31d9d7cdcd6a10d 200 Pfam PF00857 Isochorismatase family 24 196 1.9E-38 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 SUPERFAMILY SSF53383 6 435 1.84E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 Gene3D G3DSA:3.90.1150.10 1 172 7.0E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 Gene3D G3DSA:3.90.1150.10 173 253 0.022 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 Gene3D G3DSA:3.90.1150.10 254 438 2.9E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 Pfam PF00202 Aminotransferase class-III 14 434 3.7E-97 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS24485 476b0b35aaf500ca4fc6b0f5df2f41d5 440 PIRSF PIRSF000521 3 391 4.5E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS00900 e41dc9a5b811cd2d298d85a9778ea9f5 186 SUPERFAMILY SSF48498 80 177 2.89E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS00900 e41dc9a5b811cd2d298d85a9778ea9f5 186 Gene3D G3DSA:1.10.10.60 2 49 2.8E-10 T 28-03-2018 hmeg3_RS00900 e41dc9a5b811cd2d298d85a9778ea9f5 186 Gene3D G3DSA:1.10.357.10 50 183 2.5E-8 T 28-03-2018 hmeg3_RS00900 e41dc9a5b811cd2d298d85a9778ea9f5 186 SUPERFAMILY SSF46689 8 74 7.48E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS00900 e41dc9a5b811cd2d298d85a9778ea9f5 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 53 1.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS03015 b6bc0202d2c06f409996ea3623b31ec3 343 SUPERFAMILY SSF53850 28 267 9.43E-34 T 28-03-2018 hmeg3_RS03015 b6bc0202d2c06f409996ea3623b31ec3 343 Gene3D G3DSA:3.40.190.10 24 139 1.5E-8 T 28-03-2018 hmeg3_RS03015 b6bc0202d2c06f409996ea3623b31ec3 343 Pfam PF09084 NMT1/THI5 like 42 258 2.6E-41 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS03015 b6bc0202d2c06f409996ea3623b31ec3 343 Gene3D G3DSA:3.40.190.10 151 336 1.3E-24 T 28-03-2018 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 SUPERFAMILY SSF88659 78 154 2.09E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 148 9.6E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 SUPERFAMILY SSF88946 4 89 1.92E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 Gene3D G3DSA:1.10.1740.10 1 72 2.7E-14 T 28-03-2018 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 Pfam PF04542 Sigma-70 region 2 4 67 2.6E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 Pfam PF08281 Sigma-70, region 4 100 152 2.7E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS23985 0afd0bb886b089406db19900e37f2915 159 Gene3D G3DSA:1.10.10.10 79 152 2.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 SUPERFAMILY SSF53187 306 383 4.72E-55 T 28-03-2018 hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 SUPERFAMILY SSF53187 4 179 4.72E-55 T 28-03-2018 hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 Gene3D G3DSA:3.30.70.360 183 310 1.9E-23 T 28-03-2018 hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 143 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 SUPERFAMILY SSF55031 180 286 7.03E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 Pfam PF01546 Peptidase family M20/M25/M40 73 383 2.3E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 Pfam PF07687 Peptidase dimerisation domain 176 286 7.1E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 7 383 1.1E-115 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 hmeg3_RS09245 d002bc523b82566df0b94d8cc17315c3 390 Gene3D G3DSA:3.40.630.10 1 182 6.1E-29 T 28-03-2018 hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 SUPERFAMILY SSF52540 9 333 3.55E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 Pfam PF01078 Magnesium chelatase, subunit ChlI 12 186 2.3E-12 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 Gene3D G3DSA:3.40.50.410 465 635 2.9E-23 T 28-03-2018 IPR002035 von Willebrand factor, type A hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 Gene3D G3DSA:3.40.50.300 9 206 2.3E-22 T 28-03-2018 hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 Pfam PF13519 von Willebrand factor type A domain 474 578 1.0E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 10 637 3.0E-241 T 28-03-2018 IPR012804 Cobaltochelatase subunit, putative hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 SMART SM00327 470 648 1.8E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 Gene3D G3DSA:1.10.8.80 251 340 1.9E-25 T 28-03-2018 hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 SUPERFAMILY SSF53300 474 634 6.82E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A hmeg3_RS12435 f65f5caaf99a0c96234d48a42d3a22c2 654 SMART SM00382 33 209 9.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01040 ce38d7402af9b648f91003d8642301b7 382 SUPERFAMILY SSF53822 29 373 4.45E-76 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01040 ce38d7402af9b648f91003d8642301b7 382 Pfam PF13458 Periplasmic binding protein 29 366 1.9E-53 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS01040 ce38d7402af9b648f91003d8642301b7 382 Gene3D G3DSA:3.40.50.2300 13 151 3.8E-19 T 28-03-2018 hmeg3_RS01040 ce38d7402af9b648f91003d8642301b7 382 Gene3D G3DSA:3.40.50.2300 152 329 8.8E-37 T 28-03-2018 hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 Gene3D G3DSA:2.10.260.10 4 44 6.5E-4 T 28-03-2018 hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 Gene3D G3DSA:2.10.260.10 77 124 2.6E-5 T 28-03-2018 hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 67 2.0E-12 T 28-03-2018 IPR020603 MraZ domain hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 Pfam PF02381 MraZ protein, putative antitoxin-like 73 125 3.9E-13 T 28-03-2018 IPR020603 MraZ domain hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 125 7.3E-32 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 47.88 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 SUPERFAMILY SSF89447 2 128 2.77E-38 T 28-03-2018 hmeg3_RS22055 dc7158b9d96b3be1a435e3d3fcd52b3e 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 119 1.0E-47 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 hmeg3_RS07175 279a2a90bb6b12d1deba0f0aa00b542c 197 SUPERFAMILY SSF140478 25 182 2.62E-55 T 28-03-2018 IPR023353 LemA-like domain hmeg3_RS07175 279a2a90bb6b12d1deba0f0aa00b542c 197 Gene3D G3DSA:1.20.1440.20 13 195 1.0E-54 T 28-03-2018 hmeg3_RS07175 279a2a90bb6b12d1deba0f0aa00b542c 197 Pfam PF04011 LemA family 11 195 1.1E-66 T 28-03-2018 IPR007156 LemA hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 SUPERFAMILY SSF55073 346 505 8.63E-34 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 Gene3D G3DSA:3.30.450.20 170 287 1.2E-13 T 28-03-2018 hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 Gene3D G3DSA:3.30.70.270 333 511 4.5E-40 T 28-03-2018 hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 SMART SM00267 329 505 1.3E-43 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 Gene3D G3DSA:3.30.450.20 35 169 4.2E-16 T 28-03-2018 hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 Pfam PF02743 Cache domain 41 257 5.4E-19 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 Pfam PF00990 Diguanylate cyclase, GGDEF domain 341 501 1.5E-36 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05135 557049c608ae33e1f1df217da262938d 513 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 336 503 7.3E-37 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 SUPERFAMILY SSF55979 248 368 6.7E-37 T 28-03-2018 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 SMART SM00480 18 364 4.0E-115 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 6 367 1.4E-98 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 SUPERFAMILY SSF55979 6 118 8.38E-23 T 28-03-2018 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 SUPERFAMILY SSF55979 128 246 1.44E-27 T 28-03-2018 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 Gene3D G3DSA:3.10.150.10 126 249 2.2E-31 T 28-03-2018 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 367 4.8E-31 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 Gene3D G3DSA:3.10.150.10 2 121 4.1E-24 T 28-03-2018 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 6 120 9.3E-30 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 PIRSF PIRSF000804 1 368 6.2E-111 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 Gene3D G3DSA:3.10.150.10 251 368 3.5E-29 T 28-03-2018 hmeg3_RS24270 bfbcc9a3433eed468de50fb620b78391 368 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 245 4.5E-34 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS15920 53c7c2be19e1a40ec2c8a25eb64d40d4 588 Pfam PF07244 Surface antigen variable number repeat 199 269 1.8E-5 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 hmeg3_RS15920 53c7c2be19e1a40ec2c8a25eb64d40d4 588 Gene3D G3DSA:3.10.20.310 38 106 0.047 T 28-03-2018 hmeg3_RS15920 53c7c2be19e1a40ec2c8a25eb64d40d4 588 Pfam PF17243 POTRA domain TamA domain 1 31 102 6.6E-6 T 28-03-2018 IPR035243 TamA, POTRA domain 1 hmeg3_RS15920 53c7c2be19e1a40ec2c8a25eb64d40d4 588 Gene3D G3DSA:3.10.20.310 107 195 3.0E-18 T 28-03-2018 hmeg3_RS15920 53c7c2be19e1a40ec2c8a25eb64d40d4 588 Gene3D G3DSA:2.40.160.50 230 588 3.0E-51 T 28-03-2018 hmeg3_RS15920 53c7c2be19e1a40ec2c8a25eb64d40d4 588 Pfam PF01103 Surface antigen 353 577 5.3E-29 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 hmeg3_RS12590 e8d2efe6b1049d10436898bb5c9ddbed 305 SUPERFAMILY SSF51735 99 280 1.23E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12590 e8d2efe6b1049d10436898bb5c9ddbed 305 Gene3D G3DSA:3.40.50.720 114 282 3.1E-54 T 28-03-2018 hmeg3_RS12590 e8d2efe6b1049d10436898bb5c9ddbed 305 Gene3D G3DSA:3.40.50.720 2 113 1.1E-25 T 28-03-2018 hmeg3_RS12590 e8d2efe6b1049d10436898bb5c9ddbed 305 SUPERFAMILY SSF52283 1 132 1.06E-24 T 28-03-2018 hmeg3_RS12590 e8d2efe6b1049d10436898bb5c9ddbed 305 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 299 9.4E-14 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS12590 e8d2efe6b1049d10436898bb5c9ddbed 305 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 279 5.9E-51 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS07490 5d544f48d10504abd7dc8251635d63a3 205 Pfam PF00929 Exonuclease 24 192 3.2E-20 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS07490 5d544f48d10504abd7dc8251635d63a3 205 SUPERFAMILY SSF53098 21 199 5.24E-32 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS07490 5d544f48d10504abd7dc8251635d63a3 205 SMART SM00479 22 201 1.3E-16 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS07490 5d544f48d10504abd7dc8251635d63a3 205 Gene3D G3DSA:3.30.420.10 16 183 1.8E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS07490 5d544f48d10504abd7dc8251635d63a3 205 Gene3D G3DSA:1.20.5.140 184 203 4.1E-4 T 28-03-2018 hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 Pfam PF01614 Bacterial transcriptional regulator 163 288 1.2E-35 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 SUPERFAMILY SSF46785 49 119 4.87E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 Pfam PF09339 IclR helix-turn-helix domain 50 97 4.8E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 SUPERFAMILY SSF55781 113 291 7.19E-49 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 45 290 8.6E-97 T 28-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 SMART SM00346 48 136 4.5E-26 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 Gene3D G3DSA:1.10.10.10 48 108 3.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01145 ef529b925c8750d291d7a0e46e352910 292 Gene3D G3DSA:3.30.450.40 118 291 9.5E-50 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS06450 7ac5d22b3c9cd47a494b1ff73f7dacbe 358 SUPERFAMILY SSF56645 38 195 1.44E-15 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS06450 7ac5d22b3c9cd47a494b1ff73f7dacbe 358 Gene3D G3DSA:2.40.110.10 61 198 2.4E-9 T 28-03-2018 hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 Pfam PF01037 Lrp/AsnC ligand binding domain 73 146 2.7E-23 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 7.5E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 SMART SM00344 6 115 1.2E-35 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 SUPERFAMILY SSF54909 66 155 2.41E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 Gene3D G3DSA:1.10.10.10 7 58 7.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 SUPERFAMILY SSF46785 4 96 2.87E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 Gene3D G3DSA:3.30.70.920 59 152 1.1E-29 T 28-03-2018 hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 6.4E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 6.4E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS14225 7d6354a89b2836867f7c3ad395329cc1 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 6.4E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS06355 d98074129089c85f1abf9a2c4ca79315 281 Gene3D G3DSA:3.90.850.10 41 281 4.4E-79 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS06355 d98074129089c85f1abf9a2c4ca79315 281 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 277 5.9E-67 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS06355 d98074129089c85f1abf9a2c4ca79315 281 SUPERFAMILY SSF56529 63 280 2.09E-78 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS21195 8495071fba13b59fa75489c1e4186255 365 Gene3D G3DSA:3.40.640.10 1 237 4.5E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS21195 8495071fba13b59fa75489c1e4186255 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 361 1.8E-108 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS21195 8495071fba13b59fa75489c1e4186255 365 Gene3D G3DSA:3.90.1150.10 238 365 2.4E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS21195 8495071fba13b59fa75489c1e4186255 365 SUPERFAMILY SSF53383 18 364 2.53E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS21195 8495071fba13b59fa75489c1e4186255 365 PIRSF PIRSF000390 2 365 1.3E-97 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase hmeg3_RS07230 83f9423ed9bbe1d8b0331e0a4e2b0b8f 454 Pfam PF01523 Putative modulator of DNA gyrase 32 327 4.4E-63 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 hmeg3_RS07230 83f9423ed9bbe1d8b0331e0a4e2b0b8f 454 Gene3D G3DSA:3.30.2290.10 1 236 1.3E-61 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain hmeg3_RS07230 83f9423ed9bbe1d8b0331e0a4e2b0b8f 454 SUPERFAMILY SSF111283 11 453 1.57E-123 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 hmeg3_RS23350 f71999a3caaf6a0d35ca04ef463d297c 261 Pfam PF00005 ABC transporter 22 161 1.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23350 f71999a3caaf6a0d35ca04ef463d297c 261 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS23350 f71999a3caaf6a0d35ca04ef463d297c 261 SMART SM00382 31 212 2.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23350 f71999a3caaf6a0d35ca04ef463d297c 261 SUPERFAMILY SSF52540 1 221 5.6E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23350 f71999a3caaf6a0d35ca04ef463d297c 261 Gene3D G3DSA:3.40.50.300 1 241 1.8E-56 T 28-03-2018 hmeg3_RS20560 65f51120d605754050000a574e4436ca 523 Gene3D G3DSA:3.60.21.10 136 522 4.5E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS20560 65f51120d605754050000a574e4436ca 523 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 41 117 1.6E-15 T 28-03-2018 IPR032093 Phospholipase D, N-terminal hmeg3_RS20560 65f51120d605754050000a574e4436ca 523 SUPERFAMILY SSF56300 136 521 2.54E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS20560 65f51120d605754050000a574e4436ca 523 Pfam PF09423 PhoD-like phosphatase 149 505 1.9E-82 T 28-03-2018 IPR018946 Alkaline phosphatase D-related hmeg3_RS21210 002ba53b5feacc7092443ba183e36d8d 300 Pfam PF00535 Glycosyl transferase family 2 10 123 2.6E-5 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS21210 002ba53b5feacc7092443ba183e36d8d 300 Gene3D G3DSA:3.90.550.10 5 246 1.3E-8 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21210 002ba53b5feacc7092443ba183e36d8d 300 SUPERFAMILY SSF53448 6 232 8.81E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 4.8E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 SMART SM00448 1 112 5.6E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 SUPERFAMILY SSF52172 1 118 7.12E-40 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 Gene3D G3DSA:3.40.50.2300 1 121 2.1E-34 T 28-03-2018 hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 2.2E-103 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 Pfam PF00072 Response regulator receiver domain 4 113 1.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 Gene3D G3DSA:1.10.10.10 122 228 1.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 SUPERFAMILY SSF46894 125 222 1.47E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS02115 17b7524f10f1bbf3ad1a655020efaea9 231 SMART SM00862 146 221 2.0E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 183 253 1.1E-13 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 SUPERFAMILY SSF49584 148 255 3.14E-14 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 SUPERFAMILY SSF49354 27 154 3.66E-42 T 28-03-2018 IPR008962 PapD-like hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 Gene3D G3DSA:2.60.40.10 30 155 1.8E-39 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 31 154 3.7E-44 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 Gene3D G3DSA:2.60.40.10 159 261 1.6E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 PRINTS PR00969 Pili chaperone signature 80 101 2.3E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 PRINTS PR00969 Pili chaperone signature 108 125 2.3E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 PRINTS PR00969 Pili chaperone signature 136 151 2.3E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 PRINTS PR00969 Pili chaperone signature 31 40 2.3E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS02635 607391a32435a1008ece38d1ceb700d7 261 PRINTS PR00969 Pili chaperone signature 177 192 2.3E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 hmeg3_RS20000 3d09895acd3dc9b209b46d7eb4ebb70a 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 73 4.9E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS20000 3d09895acd3dc9b209b46d7eb4ebb70a 201 Gene3D G3DSA:1.20.1050.10 93 201 2.7E-26 T 28-03-2018 hmeg3_RS20000 3d09895acd3dc9b209b46d7eb4ebb70a 201 SUPERFAMILY SSF52833 1 100 3.75E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS20000 3d09895acd3dc9b209b46d7eb4ebb70a 201 Gene3D G3DSA:3.40.30.10 1 92 2.3E-23 T 28-03-2018 hmeg3_RS20000 3d09895acd3dc9b209b46d7eb4ebb70a 201 Pfam PF13410 Glutathione S-transferase, C-terminal domain 120 184 7.4E-10 T 28-03-2018 hmeg3_RS20000 3d09895acd3dc9b209b46d7eb4ebb70a 201 SUPERFAMILY SSF47616 69 200 1.67E-26 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 Gene3D G3DSA:1.10.287.950 328 523 6.3E-46 T 28-03-2018 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 Gene3D G3DSA:1.10.287.950 52 327 1.1E-15 T 28-03-2018 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 15 40 4.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 476 4.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 4.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 293 322 4.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 370 397 4.6E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 187 2.0E-13 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 487 4.9E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 SMART SM00283 272 519 1.4E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS21440 b455471d0abaa3737ac01cd3a92e6111 550 SUPERFAMILY SSF58104 248 520 1.44E-69 T 28-03-2018 hmeg3_RS10960 1be9735d81db2ca914a5a9cbde7512ce 263 Gene3D G3DSA:1.10.3720.10 1 251 1.9E-28 T 28-03-2018 hmeg3_RS10960 1be9735d81db2ca914a5a9cbde7512ce 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 253 9.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10960 1be9735d81db2ca914a5a9cbde7512ce 263 SUPERFAMILY SSF161098 5 259 8.22E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 SUPERFAMILY SSF46955 1 108 7.33E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.2E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 SMART SM00422 1 70 7.0E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 Gene3D G3DSA:1.10.1660.10 57 136 2.5E-11 T 28-03-2018 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 Gene3D G3DSA:1.10.1660.10 1 56 4.6E-21 T 28-03-2018 hmeg3_RS22275 3d8282ffdfe432f53fa0182d375aafa6 146 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 SUPERFAMILY SSF47917 383 510 1.7E-45 T 28-03-2018 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Gene3D G3DSA:1.20.150.20 384 510 7.5E-47 T 28-03-2018 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 5.5E-16 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Gene3D G3DSA:3.40.50.300 83 375 1.4E-116 T 28-03-2018 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 PIRSF PIRSF039088 1 513 3.7E-238 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.233 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 SUPERFAMILY SSF50615 10 94 1.39E-29 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 4.6E-73 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 SUPERFAMILY SSF52540 96 381 3.64E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 3.4E-45 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 Gene3D G3DSA:2.40.30.20 3 82 9.1E-34 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02435 f62644d3d15b619e7ca9a00256f81d70 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 510 1.8E-247 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 396 40.249 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 Gene3D G3DSA:3.40.640.10 44 287 7.5E-73 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 PIRSF PIRSF000521 15 398 3.1E-45 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 Gene3D G3DSA:3.90.1150.10 288 400 4.9E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 Pfam PF00202 Aminotransferase class-III 19 394 1.9E-101 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS17465 8a105e4d4f952906cb5498b15cae06c4 400 SUPERFAMILY SSF53383 12 395 2.25E-109 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS14645 5c70981936f79b5ec760319b3f13570c 709 Pfam PF10136 Site-specific recombinase 48 688 6.1E-218 T 28-03-2018 IPR011385 Putative site-specific recombinase Gcr hmeg3_RS14645 5c70981936f79b5ec760319b3f13570c 709 Gene3D G3DSA:1.20.1080.10 344 590 1.9E-29 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 hmeg3_RS14645 5c70981936f79b5ec760319b3f13570c 709 PIRSF PIRSF015380 6 703 1.2E-185 T 28-03-2018 IPR011385 Putative site-specific recombinase Gcr hmeg3_RS08615 aecd82d032c4d9914721e8840b937420 249 Gene3D G3DSA:3.60.140.10 1 249 2.0E-87 T 28-03-2018 hmeg3_RS08615 aecd82d032c4d9914721e8840b937420 249 SUPERFAMILY SSF64438 11 249 1.45E-74 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic hmeg3_RS08615 aecd82d032c4d9914721e8840b937420 249 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 40 249 1.0E-52 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase hmeg3_RS08615 aecd82d032c4d9914721e8840b937420 249 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 247 2.8E-74 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 SUPERFAMILY SSF48008 92 226 6.54E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 SUPERFAMILY SSF46785 5 78 8.08E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 6.9E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 SMART SM00895 95 221 7.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 Gene3D G3DSA:1.10.10.10 3 75 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 Pfam PF07729 FCD domain 95 219 1.3E-23 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 Gene3D G3DSA:1.20.120.530 89 235 1.6E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS17480 add270422b8dc012a7a63c7acbf9a12e 307 SMART SM00345 15 74 7.0E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 191 7.5E-45 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 SUPERFAMILY SSF90002 271 364 2.62E-22 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 Gene3D G3DSA:3.40.50.300 7 211 2.2E-39 T 28-03-2018 hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 SUPERFAMILY SSF52540 10 197 3.75E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 271 364 4.0E-23 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 Gene3D G3DSA:3.30.1220.10 230 366 6.0E-20 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS23305 ffaf6c270558b44a9e4b42aab92c7ed6 389 SMART SM00833 271 365 2.9E-24 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS01050 1346922b9a38b571877cc59aabddb3a6 368 SUPERFAMILY SSF56935 29 368 2.08E-68 T 28-03-2018 hmeg3_RS01050 1346922b9a38b571877cc59aabddb3a6 368 PRINTS PR00184 Neisseria sp. porin signature 62 87 8.6E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01050 1346922b9a38b571877cc59aabddb3a6 368 PRINTS PR00184 Neisseria sp. porin signature 311 335 8.6E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01050 1346922b9a38b571877cc59aabddb3a6 368 Gene3D G3DSA:2.40.160.10 29 368 2.5E-54 T 28-03-2018 hmeg3_RS01050 1346922b9a38b571877cc59aabddb3a6 368 Pfam PF13609 Gram-negative porin 15 339 2.6E-45 T 28-03-2018 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 PRINTS PR00412 Epoxide hydrolase signature 266 282 7.7E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 PRINTS PR00412 Epoxide hydrolase signature 78 96 7.7E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 PRINTS PR00412 Epoxide hydrolase signature 98 113 7.7E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 SUPERFAMILY SSF53474 52 324 1.51E-67 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 Gene3D G3DSA:3.40.50.1820 52 325 1.7E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 Pfam PF00561 alpha/beta hydrolase fold 73 305 1.6E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 142 155 6.6E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 113 6.6E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS05300 c3a5ca3f202867419a8d9bddb13d8faf 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 268 282 6.6E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01155 10aefa78661ed97a08224d015915bf8d 216 Pfam PF01144 Coenzyme A transferase 10 205 2.0E-41 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01155 10aefa78661ed97a08224d015915bf8d 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 8 212 4.5E-95 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01155 10aefa78661ed97a08224d015915bf8d 216 Gene3D G3DSA:3.40.1080.10 7 214 5.0E-60 T 28-03-2018 hmeg3_RS01155 10aefa78661ed97a08224d015915bf8d 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 48 56 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01155 10aefa78661ed97a08224d015915bf8d 216 SMART SM00882 10 207 1.0E-71 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01155 10aefa78661ed97a08224d015915bf8d 216 SUPERFAMILY SSF100950 9 213 8.05E-67 T 28-03-2018 hmeg3_RS13445 26337567a1e3cdd3975a3ca672298e50 85 SUPERFAMILY SSF54285 1 83 4.49E-19 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp hmeg3_RS13445 26337567a1e3cdd3975a3ca672298e50 85 Gene3D G3DSA:3.10.20.30 3 85 1.9E-17 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS13445 26337567a1e3cdd3975a3ca672298e50 85 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 85 7.3E-22 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 hmeg3_RS13445 26337567a1e3cdd3975a3ca672298e50 85 Pfam PF02597 ThiS family 6 85 2.4E-14 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 hmeg3_RS02465 cec4c5e20427f197bcaf49516870c2a0 268 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 30 252 1.7E-73 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related hmeg3_RS02465 cec4c5e20427f197bcaf49516870c2a0 268 Gene3D G3DSA:3.40.50.300 2 264 4.4E-80 T 28-03-2018 hmeg3_RS02465 cec4c5e20427f197bcaf49516870c2a0 268 PIRSF PIRSF028756 2 266 8.8E-81 T 28-03-2018 IPR016898 Polyphosphate kinase 2 hmeg3_RS02465 cec4c5e20427f197bcaf49516870c2a0 268 SUPERFAMILY SSF52540 60 249 9.4E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02465 cec4c5e20427f197bcaf49516870c2a0 268 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 7 261 1.6E-108 T 28-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 295 308 3.1E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 79 97 3.1E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 3.1E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 Pfam PF13458 Periplasmic binding protein 53 377 9.0E-68 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 SUPERFAMILY SSF53822 38 391 3.43E-80 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 Gene3D G3DSA:3.40.50.2300 22 216 5.8E-31 T 28-03-2018 hmeg3_RS01355 227c73fbb385f7bfb3929d9493d86fbc 411 Gene3D G3DSA:3.40.50.2300 217 370 1.4E-19 T 28-03-2018 hmeg3_RS05100 c50f0c0be74cc482822ca66722c2f07a 450 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 10 450 4.7E-158 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS05100 c50f0c0be74cc482822ca66722c2f07a 450 Pfam PF02447 GntP family permease 11 448 2.2E-173 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS05100 c50f0c0be74cc482822ca66722c2f07a 450 PIRSF PIRSF002746 5 450 8.1E-161 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 Gene3D G3DSA:1.10.10.10 9 29 0.0079 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 Pfam PF13407 Periplasmic binding protein domain 131 321 3.0E-35 T 28-03-2018 IPR025997 Periplasmic binding protein hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 SUPERFAMILY SSF53822 74 337 1.79E-37 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 SMART SM00354 15 85 8.8E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 61 1.3E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 Gene3D G3DSA:1.10.260.40 30 82 7.3E-16 T 28-03-2018 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 28-03-2018 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 Gene3D G3DSA:3.40.50.2300 186 325 4.1E-20 T 28-03-2018 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 SUPERFAMILY SSF47413 15 63 3.05E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS05675 6b41d1ae9719a5aa837d991f5eebcfc9 355 Gene3D G3DSA:3.40.50.2300 83 185 2.5E-10 T 28-03-2018 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 351 184.176 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 Gene3D G3DSA:3.40.50.300 28 191 7.3E-28 T 28-03-2018 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 263 336 3.8E-32 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 Gene3D G3DSA:1.10.10.10 267 337 5.4E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 SMART SM00382 61 188 5.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 SUPERFAMILY SSF46785 266 340 1.73E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 260 341 5.0E-36 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 33 336 8.2E-145 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 Gene3D G3DSA:1.10.8.60 194 264 2.5E-32 T 28-03-2018 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 19 245 1.2E-117 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 hmeg3_RS21625 2359b0b55bf769b0cbde268fd6d6eb2c 351 SUPERFAMILY SSF52540 30 258 1.83E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24330 9915b175154a2f91b18abee2b28ca23d 540 Gene3D G3DSA:3.10.105.10 305 503 5.3E-26 T 28-03-2018 hmeg3_RS24330 9915b175154a2f91b18abee2b28ca23d 540 SUPERFAMILY SSF53850 61 531 3.8E-109 T 28-03-2018 hmeg3_RS24330 9915b175154a2f91b18abee2b28ca23d 540 Gene3D G3DSA:3.90.76.10 79 211 5.1E-31 T 28-03-2018 hmeg3_RS24330 9915b175154a2f91b18abee2b28ca23d 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 453 2.8E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS24330 9915b175154a2f91b18abee2b28ca23d 540 Gene3D G3DSA:3.40.190.10 212 304 2.7E-25 T 28-03-2018 hmeg3_RS24330 9915b175154a2f91b18abee2b28ca23d 540 PIRSF PIRSF002741 28 538 6.8E-72 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 5.7E-70 T 28-03-2018 hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 SUPERFAMILY SSF51735 9 250 1.79E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 0.0015 T 28-03-2018 hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 Gene3D G3DSA:3.40.50.720 47 254 6.0E-69 T 28-03-2018 hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 Gene3D G3DSA:3.40.50.720 1 46 1.6E-8 T 28-03-2018 hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04890 438990ba7358de3d0aa90f02d2cf37b3 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS18995 b9b064e185d1e367c4b6f12cc4756f70 404 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 395 2.8E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS18995 b9b064e185d1e367c4b6f12cc4756f70 404 Gene3D G3DSA:1.10.3470.10 224 400 3.0E-19 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS18995 b9b064e185d1e367c4b6f12cc4756f70 404 Gene3D G3DSA:1.10.3470.10 47 219 4.2E-8 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS16275 84f429fa37a4b2acf0ed07f8771c5180 274 Pfam PF04951 D-aminopeptidase 1 264 1.2E-96 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase hmeg3_RS16275 84f429fa37a4b2acf0ed07f8771c5180 274 Gene3D G3DSA:3.40.50.10780 1 211 1.8E-82 T 28-03-2018 IPR027476 D-aminopeptidase, N-terminal hmeg3_RS16275 84f429fa37a4b2acf0ed07f8771c5180 274 SUPERFAMILY SSF63992 1 274 5.23E-95 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase hmeg3_RS16275 84f429fa37a4b2acf0ed07f8771c5180 274 Gene3D G3DSA:3.30.1360.130 212 270 9.4E-11 T 28-03-2018 hmeg3_RS16275 84f429fa37a4b2acf0ed07f8771c5180 274 PIRSF PIRSF015853 1 274 1.1E-97 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase hmeg3_RS15360 17eeb0ab5854d4811d96a0eea14a52c3 234 ProSitePatterns PS00501 Signal peptidases I serine active site. 150 157 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 hmeg3_RS15360 17eeb0ab5854d4811d96a0eea14a52c3 234 Pfam PF00717 Peptidase S24-like 148 217 4.9E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C hmeg3_RS15360 17eeb0ab5854d4811d96a0eea14a52c3 234 SUPERFAMILY SSF51306 100 227 6.67E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C hmeg3_RS15360 17eeb0ab5854d4811d96a0eea14a52c3 234 Gene3D G3DSA:2.10.109.10 94 230 6.0E-18 T 28-03-2018 hmeg3_RS13660 504b26bfd32e3c8ffbc53dc22ece98af 426 Pfam PF07690 Major Facilitator Superfamily 272 411 1.8E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS13660 504b26bfd32e3c8ffbc53dc22ece98af 426 Pfam PF07690 Major Facilitator Superfamily 31 271 3.9E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS13660 504b26bfd32e3c8ffbc53dc22ece98af 426 Gene3D G3DSA:1.20.1250.20 220 425 2.7E-25 T 28-03-2018 hmeg3_RS13660 504b26bfd32e3c8ffbc53dc22ece98af 426 SUPERFAMILY SSF103473 16 417 1.01E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS13660 504b26bfd32e3c8ffbc53dc22ece98af 426 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 20 422 7.3E-129 T 28-03-2018 IPR026355 Oxalate/formate antiporter GO:0005215|GO:0006810|GO:0016021 hmeg3_RS13660 504b26bfd32e3c8ffbc53dc22ece98af 426 Gene3D G3DSA:1.20.1250.20 13 203 3.5E-19 T 28-03-2018 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 Gene3D G3DSA:3.90.79.10 36 190 9.3E-28 T 28-03-2018 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 Pfam PF14803 Nudix N-terminal 2 35 1.0E-17 T 28-03-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 PRINTS PR00502 NUDIX hydrolase family signature 83 98 4.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 PRINTS PR00502 NUDIX hydrolase family signature 69 83 4.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 Pfam PF00293 NUDIX domain 41 108 2.4E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 SUPERFAMILY SSF55811 2 166 1.62E-36 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS14310 d3ca39ed8fbf87169bcb70b8d645fc38 191 Gene3D G3DSA:2.20.70.10 1 34 1.5E-16 T 28-03-2018 hmeg3_RS22850 074c01f399eb232afb13f27605b37ed3 104 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 12 102 21.178 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22850 074c01f399eb232afb13f27605b37ed3 104 Pfam PF00276 Ribosomal protein L23 13 99 9.2E-28 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22850 074c01f399eb232afb13f27605b37ed3 104 SUPERFAMILY SSF54189 8 97 3.96E-27 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22850 074c01f399eb232afb13f27605b37ed3 104 Gene3D G3DSA:3.30.70.330 10 104 3.4E-27 T 28-03-2018 hmeg3_RS10775 f58256b509b4aad093e83e4117d42160 314 Pfam PF12146 Serine aminopeptidase, S33 56 296 7.5E-22 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS10775 f58256b509b4aad093e83e4117d42160 314 Gene3D G3DSA:3.40.50.1820 21 314 6.7E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS10775 f58256b509b4aad093e83e4117d42160 314 SUPERFAMILY SSF53474 31 295 1.92E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS13775 5088b9b2f4f7d8dd72c819021641ec81 198 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 8 168 34.43 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13775 5088b9b2f4f7d8dd72c819021641ec81 198 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 121 142 - T 28-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13775 5088b9b2f4f7d8dd72c819021641ec81 198 SUPERFAMILY SSF143243 10 182 2.48E-56 T 28-03-2018 hmeg3_RS13775 5088b9b2f4f7d8dd72c819021641ec81 198 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 148 8.0E-23 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13775 5088b9b2f4f7d8dd72c819021641ec81 198 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 161 2.3E-43 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13775 5088b9b2f4f7d8dd72c819021641ec81 198 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 32 159 8.6E-41 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS07425 ac4e539fa4fa4a9066b1d5659da8dd66 344 SUPERFAMILY SSF53474 47 266 1.25E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07425 ac4e539fa4fa4a9066b1d5659da8dd66 344 Pfam PF01738 Dienelactone hydrolase family 65 269 1.4E-12 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS07425 ac4e539fa4fa4a9066b1d5659da8dd66 344 Gene3D G3DSA:3.40.50.1820 31 339 7.0E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 SUPERFAMILY SSF48300 4 61 1.7E-15 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 2.1E-30 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 Gene3D G3DSA:1.20.5.710 2 54 1.4E-16 T 28-03-2018 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 25.349 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 1.1E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 4.8E-49 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 99 1.0E-13 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 SUPERFAMILY SSF54736 54 125 2.44E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like hmeg3_RS22910 c8f32c612c0413aa4325c615e14d83a9 125 Gene3D G3DSA:3.30.1390.10 55 125 2.1E-30 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 Pfam PF00037 4Fe-4S binding domain 35 56 6.9E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 9.2E-15 T 28-03-2018 IPR022569 Ferredoxin, C-terminal hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.4E-13 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.4E-13 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.4E-13 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 Gene3D G3DSA:3.30.70.20 2 44 4.8E-13 T 28-03-2018 hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 Gene3D G3DSA:3.30.70.20 45 110 2.0E-8 T 28-03-2018 hmeg3_RS16820 9be8589c1970b9a798525caa9a2fc619 111 SUPERFAMILY SSF54862 1 84 1.36E-21 T 28-03-2018 hmeg3_RS21310 f5ddb3a15c500dcb5106caf71e3cfed6 333 Pfam PF02719 Polysaccharide biosynthesis protein 7 280 1.3E-102 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain hmeg3_RS21310 f5ddb3a15c500dcb5106caf71e3cfed6 333 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 1 326 1.3E-167 T 28-03-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00010+4.2.1.11|KEGG: 00520+4.2.1.115|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6143|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 hmeg3_RS21310 f5ddb3a15c500dcb5106caf71e3cfed6 333 Gene3D G3DSA:3.40.50.720 1 325 2.0E-57 T 28-03-2018 hmeg3_RS21310 f5ddb3a15c500dcb5106caf71e3cfed6 333 SUPERFAMILY SSF51735 1 265 1.3E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 Gene3D G3DSA:3.40.140.10 99 224 9.0E-47 T 28-03-2018 hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 Pfam PF04002 RadC-like JAB domain 104 222 1.2E-43 T 28-03-2018 IPR025657 RadC-like JAB domain hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 SUPERFAMILY SSF47781 16 88 3.5E-9 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 Gene3D G3DSA:1.10.150.20 28 87 2.9E-4 T 28-03-2018 hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 SUPERFAMILY SSF102712 149 193 3.4E-5 T 28-03-2018 hmeg3_RS18310 98208a4e54e41df01c71d0ae21be2951 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 1.2E-71 T 28-03-2018 IPR001405 RadC protein hmeg3_RS10490 bf39b3069bb00a919cdaf6c20408ed4b 165 Pfam PF05229 Spore Coat Protein U domain 32 162 2.6E-34 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS10490 bf39b3069bb00a919cdaf6c20408ed4b 165 SMART SM00972 104 162 3.2E-22 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS10885 218471ba9c6619d146157d0371bdcf57 283 Gene3D G3DSA:2.60.120.10 244 283 5.2E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS10885 218471ba9c6619d146157d0371bdcf57 283 SUPERFAMILY SSF51182 11 283 1.76E-85 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS10885 218471ba9c6619d146157d0371bdcf57 283 Gene3D G3DSA:2.60.120.10 3 243 8.5E-83 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS10885 218471ba9c6619d146157d0371bdcf57 283 Pfam PF05726 Pirin C-terminal cupin domain 179 283 8.8E-33 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 hmeg3_RS10885 218471ba9c6619d146157d0371bdcf57 283 PIRSF PIRSF006232 5 283 1.6E-96 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 hmeg3_RS10885 218471ba9c6619d146157d0371bdcf57 283 Pfam PF02678 Pirin 26 124 1.0E-35 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 SUPERFAMILY SSF46785 7 85 6.61E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 Gene3D G3DSA:3.40.190.10 186 278 7.5E-11 T 28-03-2018 hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 Gene3D G3DSA:3.40.190.10 96 185 3.7E-13 T 28-03-2018 hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.9E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 Pfam PF03466 LysR substrate binding domain 95 305 2.3E-21 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 Gene3D G3DSA:1.10.10.10 2 87 5.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16990 4dc481c867f0092c58294cb420ac5500 311 SUPERFAMILY SSF53850 92 303 9.59E-36 T 28-03-2018 hmeg3_RS08035 89429448f3de1607d7910e00f67ad0c2 197 Gene3D G3DSA:3.40.109.10 9 197 6.3E-32 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS08035 89429448f3de1607d7910e00f67ad0c2 197 SUPERFAMILY SSF55469 13 192 2.88E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS08035 89429448f3de1607d7910e00f67ad0c2 197 Pfam PF00881 Nitroreductase family 20 175 5.2E-12 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 hmeg3_RS08035 89429448f3de1607d7910e00f67ad0c2 197 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 197 44.729 T 28-03-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 322 574 4.5E-27 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 63 196 1.3E-21 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 614 708 1.8E-10 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Gene3D G3DSA:3.30.365.10 338 440 1.4E-23 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 SUPERFAMILY SSF56003 57 246 2.51E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Gene3D G3DSA:3.30.365.10 51 190 6.8E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 PIRSF PIRSF036389 12 762 6.1E-196 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 SUPERFAMILY SSF54665 222 308 3.19E-12 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Gene3D G3DSA:3.30.365.10 617 767 3.5E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 SUPERFAMILY SSF56003 328 764 2.79E-106 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Gene3D G3DSA:3.90.1170.50 205 337 1.5E-28 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 SMART SM01008 221 307 1.1E-25 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead hmeg3_RS19275 eca71a3c414101f46913af6d84a6fec2 770 Gene3D G3DSA:3.30.365.10 441 601 4.9E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 hmeg3_RS23770 f979f5c151d2d730b2c9f33aa886d103 110 Gene3D G3DSA:1.20.1290.10 5 110 6.2E-28 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS23770 f979f5c151d2d730b2c9f33aa886d103 110 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 101 4.8E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS23770 f979f5c151d2d730b2c9f33aa886d103 110 SUPERFAMILY SSF69118 10 106 6.33E-24 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 Pfam PF00753 Metallo-beta-lactamase superfamily 575 766 1.5E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 Pfam PF13567 Domain of unknown function (DUF4131) 26 200 2.3E-31 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 SMART SM00849 577 773 4.7E-4 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 154 802 3.0E-109 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 Pfam PF03772 Competence protein 246 542 5.9E-61 T 28-03-2018 IPR004477 ComEC/Rec2-related protein hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 SUPERFAMILY SSF56281 564 811 2.62E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 Gene3D G3DSA:3.60.15.10 558 816 1.4E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS09255 dad7b98a36a53254c499919bfd15b2f0 828 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 268 474 3.8E-22 T 28-03-2018 IPR004477 ComEC/Rec2-related protein hmeg3_RS00675 196e58cc21950e5177b80b41e68909af 402 Pfam PF00529 HlyD membrane-fusion protein of T1SS 108 359 8.5E-10 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS00675 196e58cc21950e5177b80b41e68909af 402 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 292 2.1E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS00675 196e58cc21950e5177b80b41e68909af 402 Gene3D G3DSA:1.20.1600.10 45 340 4.9E-29 T 28-03-2018 hmeg3_RS00675 196e58cc21950e5177b80b41e68909af 402 SUPERFAMILY SSF111369 51 299 1.57E-87 T 28-03-2018 hmeg3_RS00675 196e58cc21950e5177b80b41e68909af 402 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 374 1.4E-79 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 SUPERFAMILY SSF52768 6 307 7.2E-75 T 28-03-2018 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 PIRSF PIRSF036979 24 309 8.2E-31 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 PRINTS PR00116 Arginase signature 234 263 1.7E-7 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 PRINTS PR00116 Arginase signature 269 283 1.7E-7 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 PRINTS PR00116 Arginase signature 115 130 1.7E-7 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 TIGRFAM TIGR01227 hutG: formimidoylglutamase 6 307 5.0E-95 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 Hamap MF_00737 Formimidoylglutamase [hutG]. 1 308 41.626 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 Gene3D G3DSA:3.40.800.10 1 309 1.8E-76 T 28-03-2018 hmeg3_RS23245 59b43a808c40a4cac660ed1422366b8f 310 Pfam PF00491 Arginase family 37 305 1.3E-56 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS16825 4723d153530df9e0ca952bafed73f6e4 211 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 36 200 1.1E-40 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like hmeg3_RS16825 4723d153530df9e0ca952bafed73f6e4 211 SUPERFAMILY SSF89392 26 210 3.57E-46 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX hmeg3_RS16825 4723d153530df9e0ca952bafed73f6e4 211 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 1 208 3.6E-14 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 hmeg3_RS16825 4723d153530df9e0ca952bafed73f6e4 211 Gene3D G3DSA:2.50.20.10 24 211 1.5E-42 T 28-03-2018 hmeg3_RS16825 4723d153530df9e0ca952bafed73f6e4 211 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 11 211 28.392 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 hmeg3_RS03435 1f445637aad49d9aeb6d274719a0d6d8 158 Pfam PF02470 MlaD protein 40 117 1.9E-22 T 28-03-2018 IPR003399 Mce/MlaD hmeg3_RS03435 1f445637aad49d9aeb6d274719a0d6d8 158 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 2 148 1.6E-60 T 28-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 hmeg3_RS08755 67287e48a74164bf14f33c3658905d97 121 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 15 119 1.9E-38 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 hmeg3_RS08755 67287e48a74164bf14f33c3658905d97 121 PIRSF PIRSF000169 7 121 4.2E-39 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 hmeg3_RS08755 67287e48a74164bf14f33c3658905d97 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 4 109 1.0E-15 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08755 67287e48a74164bf14f33c3658905d97 121 SUPERFAMILY SSF81343 10 121 4.14E-31 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08755 67287e48a74164bf14f33c3658905d97 121 Gene3D G3DSA:1.20.1300.10 8 121 2.8E-21 T 28-03-2018 hmeg3_RS18905 5b62dd5100af3e8fdeb4dc2ad89d2c44 370 Gene3D G3DSA:3.40.50.2000 200 368 1.0E-25 T 28-03-2018 hmeg3_RS18905 5b62dd5100af3e8fdeb4dc2ad89d2c44 370 Gene3D G3DSA:3.40.50.2000 15 191 2.0E-18 T 28-03-2018 hmeg3_RS18905 5b62dd5100af3e8fdeb4dc2ad89d2c44 370 SUPERFAMILY SSF53756 16 369 9.1E-42 T 28-03-2018 hmeg3_RS18905 5b62dd5100af3e8fdeb4dc2ad89d2c44 370 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 211 349 4.9E-15 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 233 3.3E-34 T 28-03-2018 hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 2.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 2.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 SUPERFAMILY SSF51735 4 234 2.86E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05960 4dfa5807401696c717fa814e8ed6d172 236 Gene3D G3DSA:3.40.50.720 3 236 2.0E-49 T 28-03-2018 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 SUPERFAMILY SSF51984 2 90 1.79E-10 T 28-03-2018 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Gene3D G3DSA:3.90.190.20 563 701 3.6E-36 T 28-03-2018 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 382 700 9.8E-78 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 SUPERFAMILY SSF53244 558 702 8.24E-41 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 SUPERFAMILY SSF53623 492 556 3.66E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 SUPERFAMILY SSF53623 118 169 3.66E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 SUPERFAMILY SSF53623 380 465 3.66E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Gene3D G3DSA:3.40.1190.10 93 558 1.1E-69 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 702 29.223 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Pfam PF08245 Mur ligase middle domain 382 538 3.1E-16 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Pfam PF08245 Mur ligase middle domain 128 159 1.2E-4 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Gene3D G3DSA:3.40.50.720 2 92 5.5E-13 T 28-03-2018 hmeg3_RS22020 bc207bc6b148b1fecf8f96ae78c1c9b3 710 Pfam PF02875 Mur ligase family, glutamate ligase domain 560 634 7.4E-6 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS07670 5bdee84d842a4c327423a6da19dae7f9 86 SUPERFAMILY SSF53955 2 83 1.57E-21 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS07670 5bdee84d842a4c327423a6da19dae7f9 86 Gene3D G3DSA:1.10.530.10 1 86 7.0E-22 T 28-03-2018 hmeg3_RS07670 5bdee84d842a4c327423a6da19dae7f9 86 Pfam PF00959 Phage lysozyme 8 72 9.0E-6 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 SMART SM00996 8 469 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 8 469 6.5E-144 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 4 462 47.97 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 SUPERFAMILY SSF51735 231 390 1.84E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 80 94 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 231 390 1.3E-81 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 SMART SM00997 231 390 4.0E-114 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 SUPERFAMILY SSF52283 6 147 2.89E-111 T 28-03-2018 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 SUPERFAMILY SSF52283 183 230 2.89E-111 T 28-03-2018 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 SUPERFAMILY SSF52283 391 470 2.89E-111 T 28-03-2018 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 253 269 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 PIRSF PIRSF001109 1 470 3.3E-189 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 Gene3D G3DSA:3.40.50.1480 249 443 6.2E-82 T 28-03-2018 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 Gene3D G3DSA:3.40.50.1480 1 248 6.6E-89 T 28-03-2018 hmeg3_RS02880 79c4eeca8bad7fcb1c7ca702aba3c524 470 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 9 462 4.6E-184 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 hmeg3_RS03215 f8ee38df313d75c10b91ff9d34255e2a 257 Gene3D G3DSA:2.50.20.10 53 257 6.5E-5 T 28-03-2018 hmeg3_RS03215 f8ee38df313d75c10b91ff9d34255e2a 257 Pfam PF11306 Protein of unknown function (DUF3108) 23 250 5.9E-23 T 28-03-2018 IPR021457 Protein of unknown function DUF3108 hmeg3_RS15560 a22df9cbf44f0017b04569e37d2f6565 486 SUPERFAMILY SSF56672 17 220 6.0E-26 T 28-03-2018 hmeg3_RS22235 2d77802b33da1f0e31de4fc540ec5ba1 1413 Pfam PF05860 haemagglutination activity domain 103 208 5.7E-17 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS22235 2d77802b33da1f0e31de4fc540ec5ba1 1413 Gene3D G3DSA:2.160.20.10 92 373 1.8E-46 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS22235 2d77802b33da1f0e31de4fc540ec5ba1 1413 Gene3D G3DSA:2.160.20.10 638 773 0.18 T 28-03-2018 IPR012334 Pectin lyase fold hmeg3_RS22235 2d77802b33da1f0e31de4fc540ec5ba1 1413 SMART SM00912 96 208 8.1E-22 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS22235 2d77802b33da1f0e31de4fc540ec5ba1 1413 SUPERFAMILY SSF51126 119 371 4.71E-34 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor hmeg3_RS22235 2d77802b33da1f0e31de4fc540ec5ba1 1413 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 130 205 1.3E-18 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal hmeg3_RS15410 14a618aef2c404153a8501c2ccedc348 163 Pfam PF13420 Acetyltransferase (GNAT) domain 5 155 5.7E-30 T 28-03-2018 hmeg3_RS15410 14a618aef2c404153a8501c2ccedc348 163 SUPERFAMILY SSF55729 3 163 6.45E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS15410 14a618aef2c404153a8501c2ccedc348 163 Gene3D G3DSA:3.40.630.30 1 163 5.1E-28 T 28-03-2018 hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 SUPERFAMILY SSF53850 92 281 1.3E-31 T 28-03-2018 hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 Pfam PF03466 LysR substrate binding domain 92 276 2.6E-27 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 9.5E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 SUPERFAMILY SSF46785 4 113 3.74E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 Gene3D G3DSA:1.10.10.10 2 85 5.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 Gene3D G3DSA:3.40.190.10 88 176 3.7E-17 T 28-03-2018 hmeg3_RS19800 86001d27bda1c1e2aeb611b342c138d4 284 Gene3D G3DSA:3.40.190.10 177 254 0.0063 T 28-03-2018 hmeg3_RS01790 fa2ae6b8b6955b5c9445a30400792040 375 SUPERFAMILY SSF55073 223 374 6.98E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS01790 fa2ae6b8b6955b5c9445a30400792040 375 Pfam PF00990 Diguanylate cyclase, GGDEF domain 218 371 1.0E-43 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01790 fa2ae6b8b6955b5c9445a30400792040 375 Gene3D G3DSA:3.30.70.270 212 375 1.7E-52 T 28-03-2018 hmeg3_RS01790 fa2ae6b8b6955b5c9445a30400792040 375 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 374 1.5E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS01790 fa2ae6b8b6955b5c9445a30400792040 375 SMART SM00267 206 375 7.6E-52 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16235 4cc3de5ba8013d8623fef9db382fcdd2 412 Pfam PF01494 FAD binding domain 11 170 2.2E-19 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS16235 4cc3de5ba8013d8623fef9db382fcdd2 412 Gene3D G3DSA:3.50.50.60 3 328 7.0E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16235 4cc3de5ba8013d8623fef9db382fcdd2 412 SUPERFAMILY SSF51905 287 391 6.28E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16235 4cc3de5ba8013d8623fef9db382fcdd2 412 SUPERFAMILY SSF51905 8 179 6.28E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13210 a1de3d562971bb92a5ff701051a707a5 195 SMART SM00903 15 157 2.9E-20 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS13210 a1de3d562971bb92a5ff701051a707a5 195 SUPERFAMILY SSF50475 4 186 3.63E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS13210 a1de3d562971bb92a5ff701051a707a5 195 Gene3D G3DSA:2.30.110.10 10 195 1.8E-43 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS13210 a1de3d562971bb92a5ff701051a707a5 195 Pfam PF01613 Flavin reductase like domain 20 153 1.0E-18 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 Gene3D G3DSA:3.40.190.10 175 260 3.0E-14 T 28-03-2018 hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 SUPERFAMILY SSF53850 87 291 5.25E-40 T 28-03-2018 hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 Gene3D G3DSA:1.10.10.10 1 82 5.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 SUPERFAMILY SSF46785 1 109 3.65E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 Gene3D G3DSA:3.40.190.10 89 174 1.1E-18 T 28-03-2018 hmeg3_RS13625 6c0a371d3d7d849d49e6312c9170657c 300 Pfam PF03466 LysR substrate binding domain 86 287 2.2E-42 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS22185 bc9263e30d58409f7f533cb31111d9f8 502 Gene3D G3DSA:3.30.750.24 401 491 1.0E-16 T 28-03-2018 IPR002645 STAS domain hmeg3_RS22185 bc9263e30d58409f7f533cb31111d9f8 502 Pfam PF01740 STAS domain 411 491 2.1E-8 T 28-03-2018 IPR002645 STAS domain hmeg3_RS22185 bc9263e30d58409f7f533cb31111d9f8 502 Pfam PF00916 Sulfate permease family 16 366 1.7E-48 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 hmeg3_RS22185 bc9263e30d58409f7f533cb31111d9f8 502 SUPERFAMILY SSF52091 409 493 5.69E-14 T 28-03-2018 IPR002645 STAS domain hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PIRSF PIRSF001415 4 337 4.0E-146 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 SMART SM01004 11 335 4.9E-232 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 SUPERFAMILY SSF51569 9 336 5.13E-142 T 28-03-2018 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 254 266 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 Pfam PF00490 Delta-aminolevulinic acid dehydratase 15 333 4.7E-138 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 254 270 4.9E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 162 181 4.9E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 200 219 4.9E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 309 328 4.9E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 131 145 4.9E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 279 294 4.9E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 hmeg3_RS22650 07ab371e361cb5a894ce70e02679023c 337 Gene3D G3DSA:3.20.20.70 2 337 1.2E-149 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PIRSF PIRSF006648 2 258 3.3E-29 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 33 54 2.8E-39 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 108 133 2.8E-39 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 2.8E-39 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 145 169 2.8E-39 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 63 85 2.8E-39 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 202 221 2.8E-39 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 Pfam PF01061 ABC-2 type transporter 17 222 6.0E-27 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 hmeg3_RS22715 a8b78a9832451fd5f3ec32133a227a17 258 TIGRFAM TIGR01291 nodJ: ABC-2 type transporter, NodJ family 13 257 1.5E-71 T 28-03-2018 IPR005981 ABC-2 type transporter, NodJ GO:0005215|GO:0009877|GO:0015772|GO:0016020 hmeg3_RS11085 ceb151d938c762955bc88025c4956bab 324 Gene3D G3DSA:1.10.3720.10 2 308 2.8E-38 T 28-03-2018 hmeg3_RS11085 ceb151d938c762955bc88025c4956bab 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 7.1E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11085 ceb151d938c762955bc88025c4956bab 324 SUPERFAMILY SSF161098 90 306 5.72E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 SMART SM00283 263 510 1.2E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 Gene3D G3DSA:1.10.287.950 31 318 8.0E-18 T 28-03-2018 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 Gene3D G3DSA:1.10.287.950 319 513 1.2E-47 T 28-03-2018 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 5.5E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 5.5E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 5.5E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 5.5E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 5.5E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 171 3.2E-18 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 477 1.4E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 SUPERFAMILY SSF58104 230 511 4.97E-75 T 28-03-2018 hmeg3_RS24095 2fff393d50adbf2ddb51721c1fb3669a 513 SMART SM00304 210 262 3.0E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 Gene3D G3DSA:3.30.43.10 1 104 5.6E-26 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 SUPERFAMILY SSF56176 15 226 2.71E-69 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 Gene3D G3DSA:1.10.45.10 427 466 5.2E-18 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 7.7E-68 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 Pfam PF01565 FAD binding domain 52 188 1.8E-39 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 Gene3D G3DSA:3.30.465.10 105 248 6.7E-46 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS04830 51e82824592bad89f8dea7ca2de81a89 469 SUPERFAMILY SSF55103 229 469 9.65E-74 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 PIRSF PIRSF000018 15 428 3.6E-142 T 28-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 Gene3D G3DSA:1.10.760.10 170 312 1.9E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 Gene3D G3DSA:1.10.760.10 313 427 3.1E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 Gene3D G3DSA:1.10.760.10 23 159 2.2E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 Pfam PF00034 Cytochrome c 47 146 8.8E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 Pfam PF00034 Cytochrome c 321 407 3.8E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 SUPERFAMILY SSF46626 42 168 2.61E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 SUPERFAMILY SSF46626 191 304 4.35E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06570 8ebe8382c49332554c9c9b446efc919f 429 SUPERFAMILY SSF46626 322 424 3.95E-25 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 SUPERFAMILY SSF53850 91 298 1.12E-33 T 28-03-2018 hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 Pfam PF03466 LysR substrate binding domain 90 296 2.1E-28 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 Gene3D G3DSA:1.10.10.10 4 88 2.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 Gene3D G3DSA:3.40.190.10 178 267 1.6E-15 T 28-03-2018 hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 Gene3D G3DSA:3.40.190.10 95 177 5.5E-11 T 28-03-2018 hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 SUPERFAMILY SSF46785 5 113 1.27E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20595 a73be08c7ca93813f3f1b65ad677bf61 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 8.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS21365 ea4aaafcbac0ba6034bf4687afc03bf0 272 Pfam PF00149 Calcineurin-like phosphoesterase 1 152 5.9E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS21365 ea4aaafcbac0ba6034bf4687afc03bf0 272 PIRSF PIRSF000903 1 272 5.6E-107 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 hmeg3_RS21365 ea4aaafcbac0ba6034bf4687afc03bf0 272 SUPERFAMILY SSF56300 1 256 1.23E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS21365 ea4aaafcbac0ba6034bf4687afc03bf0 272 Gene3D G3DSA:3.60.21.10 1 271 3.0E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS21365 ea4aaafcbac0ba6034bf4687afc03bf0 272 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 269 5.7E-82 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 hmeg3_RS21365 ea4aaafcbac0ba6034bf4687afc03bf0 272 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 268 45.464 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 SMART SM00938 4 105 4.3E-65 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 PIRSF PIRSF039144 1 112 2.5E-52 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.2E-40 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 SUPERFAMILY SSF54913 1 112 3.5E-44 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 Gene3D G3DSA:3.30.70.120 1 109 4.3E-48 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 PRINTS PR00340 P-II protein signature 52 75 8.0E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 PRINTS PR00340 P-II protein signature 83 103 8.0E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 PRINTS PR00340 P-II protein signature 23 41 8.0E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS23010 fd1ce44b6bc5b5546be1c2fed98a3f0c 112 PRINTS PR00340 P-II protein signature 2 17 8.0E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS04200 ae5d96b739c5f26010a657cdcbfd7066 174 Pfam PF12915 Protein of unknown function (DUF3833) 11 172 6.8E-70 T 28-03-2018 IPR024409 Protein of unknown function DUF3833 hmeg3_RS14465 0e2441e73e2d0ba67079937b2e54e712 398 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 2 382 70.462 T 28-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 hmeg3_RS14465 0e2441e73e2d0ba67079937b2e54e712 398 Gene3D G3DSA:3.20.20.30 1 358 2.4E-91 T 28-03-2018 hmeg3_RS14465 0e2441e73e2d0ba67079937b2e54e712 398 SUPERFAMILY SSF51679 1 353 2.09E-96 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS14465 0e2441e73e2d0ba67079937b2e54e712 398 Pfam PF00296 Luciferase-like monooxygenase 1 327 5.0E-90 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS14465 0e2441e73e2d0ba67079937b2e54e712 398 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 351 1.1E-190 T 28-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 hmeg3_RS16095 2b29762189c0b04c4eac06a25a08ece8 268 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 64 77 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS16095 2b29762189c0b04c4eac06a25a08ece8 268 SMART SM00062 41 261 8.1E-50 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS16095 2b29762189c0b04c4eac06a25a08ece8 268 Gene3D G3DSA:3.40.190.10 184 265 1.4E-9 T 28-03-2018 hmeg3_RS16095 2b29762189c0b04c4eac06a25a08ece8 268 SUPERFAMILY SSF53850 38 263 1.05E-54 T 28-03-2018 hmeg3_RS16095 2b29762189c0b04c4eac06a25a08ece8 268 Gene3D G3DSA:3.40.190.10 30 183 5.1E-36 T 28-03-2018 hmeg3_RS16095 2b29762189c0b04c4eac06a25a08ece8 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 259 2.6E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS03450 f94bc80e085a41828ca453446b0cf048 94 Pfam PF13466 STAS domain 7 78 7.1E-16 T 28-03-2018 IPR002645 STAS domain hmeg3_RS03450 f94bc80e085a41828ca453446b0cf048 94 Gene3D G3DSA:3.30.750.24 1 93 2.7E-8 T 28-03-2018 IPR002645 STAS domain hmeg3_RS03450 f94bc80e085a41828ca453446b0cf048 94 SUPERFAMILY SSF52091 4 84 1.96E-10 T 28-03-2018 IPR002645 STAS domain hmeg3_RS17770 54cc515ef0690db67e8f1c995f4f90b5 785 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 172 6.6E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS17770 54cc515ef0690db67e8f1c995f4f90b5 785 Gene3D G3DSA:2.40.170.20 171 785 5.8E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS17770 54cc515ef0690db67e8f1c995f4f90b5 785 Pfam PF00593 TonB dependent receptor 277 784 2.2E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS17770 54cc515ef0690db67e8f1c995f4f90b5 785 Gene3D G3DSA:2.170.130.10 32 170 1.4E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS17770 54cc515ef0690db67e8f1c995f4f90b5 785 SUPERFAMILY SSF56935 34 785 2.12E-97 T 28-03-2018 hmeg3_RS17770 54cc515ef0690db67e8f1c995f4f90b5 785 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 47 785 1.3E-101 T 28-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 hmeg3_RS01545 72ca5e2a3b68d647411b3ddc1aecc444 498 SUPERFAMILY SSF53383 86 385 4.37E-8 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS01545 72ca5e2a3b68d647411b3ddc1aecc444 498 Gene3D G3DSA:3.40.640.10 51 352 2.1E-12 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS07805 c154e9a64958552c2ea07adfa804b72e 268 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 66 239 1.3E-39 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 hmeg3_RS07805 c154e9a64958552c2ea07adfa804b72e 268 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 67 237 2.0E-54 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.2E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.2E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.2E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.2E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.2E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.2E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 PIRSF PIRSF002133 1 124 2.5E-53 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.207 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 SUPERFAMILY SSF50249 2 123 1.03E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 8.1E-70 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 Gene3D G3DSA:2.40.50.140 1 127 3.8E-64 T 28-03-2018 hmeg3_RS22885 a2c6c354468a6d5dca38a8a0724e8b6b 127 Pfam PF00164 Ribosomal protein S12/S23 16 123 8.4E-42 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS12380 7fc2b937b79ddd5b52466dfcf7fe4d2a 218 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 5 205 4.8E-80 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 hmeg3_RS12380 7fc2b937b79ddd5b52466dfcf7fe4d2a 218 Pfam PF00881 Nitroreductase family 17 181 1.3E-28 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 hmeg3_RS12380 7fc2b937b79ddd5b52466dfcf7fe4d2a 218 SUPERFAMILY SSF55469 13 212 1.3E-48 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS12380 7fc2b937b79ddd5b52466dfcf7fe4d2a 218 Gene3D G3DSA:3.40.109.10 1 207 5.5E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 Gene3D G3DSA:3.40.50.150 88 279 2.7E-39 T 28-03-2018 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 25 278 7.2E-73 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 SUPERFAMILY SSF53335 15 276 1.1E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 13 279 41.105 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 Pfam PF05175 Methyltransferase small domain 100 196 2.4E-16 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 275 2.6E-87 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 Gene3D G3DSA:1.10.8.10 11 87 1.4E-16 T 28-03-2018 hmeg3_RS02935 c3ecc0cc194ddeb477d329323ea32fa7 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 184 190 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS16075 05063fdb8627a25b4f994d845547d929 248 Gene3D G3DSA:3.20.20.150 1 248 4.2E-27 T 28-03-2018 hmeg3_RS16075 05063fdb8627a25b4f994d845547d929 248 SUPERFAMILY SSF51658 3 247 3.66E-54 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain hmeg3_RS05460 42c2212e944b33014f8737c38eb5683a 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 9.7E-11 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain hmeg3_RS05460 42c2212e944b33014f8737c38eb5683a 100 SUPERFAMILY SSF54909 1 95 4.22E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS05460 42c2212e944b33014f8737c38eb5683a 100 Gene3D G3DSA:3.30.70.100 1 96 1.1E-19 T 28-03-2018 hmeg3_RS03260 2a7832d24eb23a45000e49647bdb0062 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03260 2a7832d24eb23a45000e49647bdb0062 264 Gene3D G3DSA:3.40.50.300 1 237 2.3E-51 T 28-03-2018 hmeg3_RS03260 2a7832d24eb23a45000e49647bdb0062 264 SMART SM00382 31 226 2.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03260 2a7832d24eb23a45000e49647bdb0062 264 Pfam PF00005 ABC transporter 22 177 1.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03260 2a7832d24eb23a45000e49647bdb0062 264 SUPERFAMILY SSF52540 1 235 7.46E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 Pfam PF00072 Response regulator receiver domain 5 107 1.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 PIRSF PIRSF000876 1 354 1.7E-137 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 SUPERFAMILY SSF52172 1 107 1.57E-28 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 Pfam PF01339 CheB methylesterase 167 344 1.0E-58 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 SUPERFAMILY SSF52738 164 351 1.31E-71 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 Gene3D G3DSA:3.40.50.180 157 357 1.8E-75 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 Gene3D G3DSA:3.40.50.2300 1 145 6.8E-28 T 28-03-2018 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 SMART SM00448 3 122 1.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08125 a3efa7573ba676555fb05a619b5ec40e 359 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 350 40.709 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 hmeg3_RS04225 dd9585e4459506d963e0a3cff8b1ac5c 541 SUPERFAMILY SSF81296 425 534 6.86E-28 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS04225 dd9585e4459506d963e0a3cff8b1ac5c 541 PIRSF PIRSF006281 2 536 6.8E-185 T 28-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D hmeg3_RS04225 dd9585e4459506d963e0a3cff8b1ac5c 541 Gene3D G3DSA:2.70.98.10 40 422 3.1E-160 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 hmeg3_RS04225 dd9585e4459506d963e0a3cff8b1ac5c 541 SUPERFAMILY SSF74650 40 425 5.34E-141 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS04225 dd9585e4459506d963e0a3cff8b1ac5c 541 Gene3D G3DSA:2.60.40.10 426 536 2.7E-29 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS04225 dd9585e4459506d963e0a3cff8b1ac5c 541 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 40 532 4.7E-182 T 28-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 hmeg3_RS10330 ce9e35915f6e240de98e55a3a82443d6 342 SUPERFAMILY SSF52540 14 223 3.4E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10330 ce9e35915f6e240de98e55a3a82443d6 342 Gene3D G3DSA:3.40.50.300 14 190 1.8E-27 T 28-03-2018 hmeg3_RS10330 ce9e35915f6e240de98e55a3a82443d6 342 Pfam PF13177 DNA polymerase III, delta subunit 20 188 2.0E-42 T 28-03-2018 hmeg3_RS10330 ce9e35915f6e240de98e55a3a82443d6 342 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 18 222 4.0E-63 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10330 ce9e35915f6e240de98e55a3a82443d6 342 Gene3D G3DSA:1.20.272.10 226 342 6.1E-12 T 28-03-2018 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 SUPERFAMILY SSF53901 269 387 1.06E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 Gene3D G3DSA:3.40.47.10 260 388 2.1E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 Pfam PF02803 Thiolase, C-terminal domain 273 387 4.6E-19 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 Pfam PF00108 Thiolase, N-terminal domain 5 255 8.9E-34 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 Gene3D G3DSA:3.40.47.10 1 259 1.1E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 PIRSF PIRSF000429 1 388 3.9E-80 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 SUPERFAMILY SSF53901 3 261 6.01E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16415 d2f772810ad86da5c15bd927b554ab3a 388 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 386 8.5E-75 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS06705 177aaf02dfd47f44ac24130db9b7c678 151 Pfam PF00583 Acetyltransferase (GNAT) family 23 129 3.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS06705 177aaf02dfd47f44ac24130db9b7c678 151 Gene3D G3DSA:3.40.630.30 1 151 9.6E-29 T 28-03-2018 hmeg3_RS06705 177aaf02dfd47f44ac24130db9b7c678 151 SUPERFAMILY SSF55729 1 151 1.17E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS17590 77ee11d9581b45b92515d2af74681a18 534 SUPERFAMILY SSF55931 8 521 1.63E-189 T 28-03-2018 hmeg3_RS17590 77ee11d9581b45b92515d2af74681a18 534 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 7 524 1.0E-202 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 hmeg3_RS17590 77ee11d9581b45b92515d2af74681a18 534 Pfam PF04262 Glutamate-cysteine ligase 10 387 3.5E-165 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 hmeg3_RS17590 77ee11d9581b45b92515d2af74681a18 534 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 534 215.323 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Pfam PF00141 Peroxidase 74 385 3.8E-46 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Pfam PF00141 Peroxidase 391 699 6.8E-37 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00458 Haem peroxidase superfamily signature 161 173 1.8E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00458 Haem peroxidase superfamily signature 143 160 1.8E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00458 Haem peroxidase superfamily signature 307 322 1.8E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00458 Haem peroxidase superfamily signature 83 97 1.8E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00458 Haem peroxidase superfamily signature 248 263 1.8E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Gene3D G3DSA:1.10.520.10 15 218 2.5E-57 T 28-03-2018 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 469 495 6.6E-53 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 19 41 6.6E-53 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 45 58 6.6E-53 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 60 85 6.6E-53 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 256 279 6.6E-53 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Hamap MF_01961 Catalase-peroxidase [katG]. 2 725 41.6 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 ProSitePatterns PS00436 Peroxidases active site signature. 83 94 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 SUPERFAMILY SSF48113 419 724 1.16E-113 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 SUPERFAMILY SSF48113 15 418 3.39E-145 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 6 724 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Gene3D G3DSA:1.10.520.10 430 591 4.8E-42 T 28-03-2018 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Gene3D G3DSA:1.10.420.10 592 700 6.0E-35 T 28-03-2018 hmeg3_RS22375 9a169d20be024f21b329c1806b40a763 725 Gene3D G3DSA:1.10.420.10 220 386 3.5E-40 T 28-03-2018 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 5.3E-255 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 Hamap MF_00600 60 kDa chaperonin [groL]. 2 546 41.591 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 SUPERFAMILY SSF52029 184 376 2.09E-82 T 28-03-2018 IPR027409 GroEL-like apical domain hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 SUPERFAMILY SSF54849 137 203 2.15E-24 T 28-03-2018 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 1.3E-99 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 Gene3D G3DSA:3.50.7.10 186 373 2.0E-96 T 28-03-2018 IPR027409 GroEL-like apical domain hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 SUPERFAMILY SSF48592 406 521 1.53E-75 T 28-03-2018 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 SUPERFAMILY SSF48592 7 134 1.53E-75 T 28-03-2018 hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 Gene3D G3DSA:1.10.560.10 374 516 4.3E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain hmeg3_RS05825 d03ffb8344749ed656dfd9c729f0eaa3 550 Gene3D G3DSA:1.10.560.10 1 185 2.1E-40 T 28-03-2018 IPR027413 GroEL-like equatorial domain hmeg3_RS22215 a66c1b3d719fb9f90a1f60dff7cb925f 551 Gene3D G3DSA:3.90.226.10 160 474 6.3E-12 T 28-03-2018 hmeg3_RS22215 a66c1b3d719fb9f90a1f60dff7cb925f 551 SUPERFAMILY SSF52096 176 284 1.29E-13 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS15265 64c764b3a10ae58880dc5e39c37d2ed9 656 Pfam PF00593 TonB dependent receptor 217 654 8.9E-40 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS15265 64c764b3a10ae58880dc5e39c37d2ed9 656 Gene3D G3DSA:2.170.130.10 39 181 2.5E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS15265 64c764b3a10ae58880dc5e39c37d2ed9 656 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 171 1.2E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS15265 64c764b3a10ae58880dc5e39c37d2ed9 656 Gene3D G3DSA:2.40.170.20 182 656 8.6E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS15265 64c764b3a10ae58880dc5e39c37d2ed9 656 SUPERFAMILY SSF56935 44 656 3.24E-101 T 28-03-2018 hmeg3_RS00790 65e0bb8fccdad65840937131e8f836fc 305 Pfam PF00892 EamA-like transporter family 158 293 2.4E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS00790 65e0bb8fccdad65840937131e8f836fc 305 Pfam PF00892 EamA-like transporter family 16 147 8.7E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS00790 65e0bb8fccdad65840937131e8f836fc 305 SUPERFAMILY SSF103481 52 147 5.1E-10 T 28-03-2018 hmeg3_RS00790 65e0bb8fccdad65840937131e8f836fc 305 SUPERFAMILY SSF103481 191 295 1.18E-12 T 28-03-2018 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 Gene3D G3DSA:3.30.565.10 224 377 5.5E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 SMART SM00387 261 376 2.3E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 SUPERFAMILY SSF47384 147 216 1.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 Gene3D G3DSA:1.10.287.130 141 213 2.6E-9 T 28-03-2018 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 262 373 4.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 Pfam PF00512 His Kinase A (phospho-acceptor) domain 152 213 1.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 SUPERFAMILY SSF55874 206 373 1.76E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 SMART SM00388 151 217 3.9E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 312 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12105 785e0cf4fb0fc13552b1a816ed1fc5d5 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 Gene3D G3DSA:1.10.390.10 285 451 2.3E-50 T 28-03-2018 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 SUPERFAMILY SSF55486 209 456 4.27E-74 T 28-03-2018 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 Gene3D G3DSA:1.25.50.10 560 897 5.9E-134 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 SUPERFAMILY SSF63737 5 196 3.27E-39 T 28-03-2018 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 896 0.0 T 28-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 562 896 2.8E-128 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 Pfam PF01433 Peptidase family M1 domain 212 447 5.2E-55 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 3.5E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 317 329 3.5E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 298 313 3.5E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 180 195 3.5E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 452 559 8.5E-32 T 28-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold hmeg3_RS18775 cc2b31a763d2a3a0668aea8a0adcf9f0 898 Gene3D G3DSA:2.60.40.1730 16 197 4.4E-25 T 28-03-2018 hmeg3_RS24575 72e696fe65b324293ad84af68a8446d5 187 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 37 171 9.6E-14 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 hmeg3_RS24575 72e696fe65b324293ad84af68a8446d5 187 Gene3D G3DSA:3.30.530.20 28 179 9.4E-21 T 28-03-2018 IPR023393 START-like domain hmeg3_RS24575 72e696fe65b324293ad84af68a8446d5 187 SUPERFAMILY SSF55961 30 177 3.14E-18 T 28-03-2018 hmeg3_RS00560 fb75e9f34d938cac757f10cc100fd44a 302 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 28-03-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111 hmeg3_RS00560 fb75e9f34d938cac757f10cc100fd44a 302 Pfam PF00682 HMGL-like 6 280 1.6E-54 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 hmeg3_RS00560 fb75e9f34d938cac757f10cc100fd44a 302 SUPERFAMILY SSF51569 1 290 7.87E-69 T 28-03-2018 hmeg3_RS00560 fb75e9f34d938cac757f10cc100fd44a 302 Gene3D G3DSA:3.20.20.70 2 299 1.2E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 285 1.6E-82 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 Pfam PF00288 GHMP kinases N terminal domain 89 146 2.2E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 Pfam PF08544 GHMP kinases C terminal 199 270 1.4E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 SUPERFAMILY SSF54211 8 159 4.63E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 280 32.67 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 Gene3D G3DSA:3.30.70.890 164 288 4.4E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 Gene3D G3DSA:3.30.230.10 6 162 2.7E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 SUPERFAMILY SSF55060 164 285 6.23E-30 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain hmeg3_RS04310 ee09b889b521ac6dc421853bc7aaa870 289 PIRSF PIRSF010376 4 288 5.7E-86 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 hmeg3_RS16295 9ca9ce9e45cb8fc70da5a30e2365bc04 522 Gene3D G3DSA:3.40.190.10 191 283 3.8E-25 T 28-03-2018 hmeg3_RS16295 9ca9ce9e45cb8fc70da5a30e2365bc04 522 Gene3D G3DSA:3.90.76.10 45 190 2.4E-36 T 28-03-2018 hmeg3_RS16295 9ca9ce9e45cb8fc70da5a30e2365bc04 522 Gene3D G3DSA:3.10.105.10 284 496 3.7E-52 T 28-03-2018 hmeg3_RS16295 9ca9ce9e45cb8fc70da5a30e2365bc04 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 437 2.2E-93 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS16295 9ca9ce9e45cb8fc70da5a30e2365bc04 522 SUPERFAMILY SSF53850 37 521 2.48E-135 T 28-03-2018 hmeg3_RS16295 9ca9ce9e45cb8fc70da5a30e2365bc04 522 PIRSF PIRSF002741 10 521 1.8E-103 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS11770 f89565780c495e7137c0fbc13bab94a9 307 Pfam PF07484 Phage Tail Collar Domain 42 98 3.6E-15 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS11770 f89565780c495e7137c0fbc13bab94a9 307 Gene3D G3DSA:3.90.1340.10 27 102 6.4E-13 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS11770 f89565780c495e7137c0fbc13bab94a9 307 SUPERFAMILY SSF88874 56 184 2.75E-20 T 28-03-2018 hmeg3_RS15380 9ff9e2ae8abcc36a0c91fb116e02bff7 315 Pfam PF01738 Dienelactone hydrolase family 108 301 5.3E-7 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS15380 9ff9e2ae8abcc36a0c91fb116e02bff7 315 SUPERFAMILY SSF53474 30 283 1.39E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS15380 9ff9e2ae8abcc36a0c91fb116e02bff7 315 Gene3D G3DSA:3.40.50.1820 29 300 1.4E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS24225 d37a18893337a242baf72a70d60b1330 505 Gene3D G3DSA:3.40.605.10 2 272 3.8E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS24225 d37a18893337a242baf72a70d60b1330 505 SUPERFAMILY SSF53720 5 489 3.93E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS24225 d37a18893337a242baf72a70d60b1330 505 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS24225 d37a18893337a242baf72a70d60b1330 505 Gene3D G3DSA:3.40.309.10 273 468 3.1E-68 T 28-03-2018 hmeg3_RS24225 d37a18893337a242baf72a70d60b1330 505 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 489 8.5E-205 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 hmeg3_RS24225 d37a18893337a242baf72a70d60b1330 505 Pfam PF00171 Aldehyde dehydrogenase family 19 485 1.2E-142 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS11470 fe805bd2642e56a80793d158d5197de7 152 SUPERFAMILY SSF52402 8 152 2.26E-31 T 28-03-2018 hmeg3_RS11470 fe805bd2642e56a80793d158d5197de7 152 PRINTS PR01438 Universal stress protein signature 9 27 1.6E-14 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11470 fe805bd2642e56a80793d158d5197de7 152 PRINTS PR01438 Universal stress protein signature 112 124 1.6E-14 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11470 fe805bd2642e56a80793d158d5197de7 152 PRINTS PR01438 Universal stress protein signature 130 152 1.6E-14 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11470 fe805bd2642e56a80793d158d5197de7 152 Pfam PF00582 Universal stress protein family 8 152 2.7E-27 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS11470 fe805bd2642e56a80793d158d5197de7 152 Gene3D G3DSA:3.40.50.620 3 152 7.0E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 6.9E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 Pfam PF03466 LysR substrate binding domain 94 292 6.0E-34 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 Gene3D G3DSA:1.10.10.10 2 87 4.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 SUPERFAMILY SSF53850 94 293 1.04E-35 T 28-03-2018 hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 Gene3D G3DSA:3.40.190.10 92 175 2.2E-17 T 28-03-2018 hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 SUPERFAMILY SSF46785 7 113 1.73E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21585 3673781ec771ea8ccb9c322075462fd4 295 Gene3D G3DSA:3.40.190.10 176 261 2.4E-20 T 28-03-2018 hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 SUPERFAMILY SSF52540 80 298 1.87E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 Gene3D G3DSA:1.10.40.50 239 302 3.0E-20 T 28-03-2018 hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 Gene3D G3DSA:2.40.50.140 7 66 2.5E-13 T 28-03-2018 hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 Gene3D G3DSA:3.40.50.300 73 237 5.5E-16 T 28-03-2018 hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 SUPERFAMILY SSF50249 13 68 9.42E-6 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 44 295 1.3E-61 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 11 302 32.42 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 hmeg3_RS06885 5ff74c17e2e1ee1b95aee41ee4f03ba6 303 Pfam PF03193 RsgA GTPase 64 237 1.0E-47 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 hmeg3_RS19815 759bfdd743c10f7c54e1b2917a22aec1 152 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 112 122 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site hmeg3_RS19815 759bfdd743c10f7c54e1b2917a22aec1 152 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 142 1.1E-34 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 hmeg3_RS19815 759bfdd743c10f7c54e1b2917a22aec1 152 Pfam PF02130 Uncharacterized protein family UPF0054 25 141 3.9E-33 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 hmeg3_RS19815 759bfdd743c10f7c54e1b2917a22aec1 152 Gene3D G3DSA:3.40.390.30 2 152 5.2E-45 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 hmeg3_RS19815 759bfdd743c10f7c54e1b2917a22aec1 152 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 7 146 21.928 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 hmeg3_RS19815 759bfdd743c10f7c54e1b2917a22aec1 152 SUPERFAMILY SSF55486 22 148 3.91E-42 T 28-03-2018 hmeg3_RS10530 8b162d04860b8aca7d8b303e8dc8a281 145 Gene3D G3DSA:3.40.50.2300 1 145 5.8E-26 T 28-03-2018 hmeg3_RS10530 8b162d04860b8aca7d8b303e8dc8a281 145 SMART SM00448 6 130 5.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10530 8b162d04860b8aca7d8b303e8dc8a281 145 SUPERFAMILY SSF52172 2 139 5.41E-29 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10530 8b162d04860b8aca7d8b303e8dc8a281 145 Pfam PF00072 Response regulator receiver domain 8 128 3.0E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS08210 39cc19ac533892edc4cf8d7658ebef0a 246 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 5.0E-36 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G hmeg3_RS08210 39cc19ac533892edc4cf8d7658ebef0a 246 SUPERFAMILY SSF117143 78 204 9.15E-22 T 28-03-2018 hmeg3_RS08210 39cc19ac533892edc4cf8d7658ebef0a 246 Pfam PF00460 Flagella basal body rod protein 5 35 4.3E-6 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 hmeg3_RS08210 39cc19ac533892edc4cf8d7658ebef0a 246 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 171 241 5.9E-22 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain hmeg3_RS08210 39cc19ac533892edc4cf8d7658ebef0a 246 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 223 1.6E-57 T 28-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 hmeg3_RS00315 2fef13bd0b10ed3b12a7081590cc006e 284 SUPERFAMILY SSF52540 41 282 9.06E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00315 2fef13bd0b10ed3b12a7081590cc006e 284 Gene3D G3DSA:3.40.50.300 26 283 5.3E-50 T 28-03-2018 hmeg3_RS00315 2fef13bd0b10ed3b12a7081590cc006e 284 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 41 284 3.2E-116 T 28-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD hmeg3_RS00315 2fef13bd0b10ed3b12a7081590cc006e 284 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 262 283 9.5E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS00315 2fef13bd0b10ed3b12a7081590cc006e 284 Pfam PF00005 ABC transporter 58 212 3.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS08360 57bc1abc789ffdb926136f6aced069a8 119 Pfam PF03646 FlaG protein 20 116 4.9E-22 T 28-03-2018 IPR005186 FlaG protein hmeg3_RS08360 57bc1abc789ffdb926136f6aced069a8 119 Gene3D G3DSA:3.30.160.170 17 115 1.5E-21 T 28-03-2018 IPR005186 FlaG protein hmeg3_RS08360 57bc1abc789ffdb926136f6aced069a8 119 SUPERFAMILY SSF160214 18 119 1.44E-22 T 28-03-2018 IPR005186 FlaG protein hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Gene3D G3DSA:1.10.1740.10 2 83 1.4E-20 T 28-03-2018 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 SUPERFAMILY SSF88659 86 160 4.1E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 13 235 2.1E-84 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 2 238 60.711 T 28-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Pfam PF04545 Sigma-70, region 4 185 232 9.7E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Gene3D G3DSA:1.10.10.10 86 133 3.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 SUPERFAMILY SSF88659 150 240 1.63E-19 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 PRINTS PR00046 Major sigma-70 factor signature 40 53 7.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 PRINTS PR00046 Major sigma-70 factor signature 205 220 7.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 PRINTS PR00046 Major sigma-70 factor signature 220 231 7.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 PRINTS PR00046 Major sigma-70 factor signature 64 72 7.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 PRINTS PR00046 Major sigma-70 factor signature 188 200 7.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Pfam PF04539 Sigma-70 region 3 94 165 1.6E-10 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 PIRSF PIRSF000770 1 240 1.7E-42 T 28-03-2018 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Pfam PF04542 Sigma-70 region 2 13 85 7.5E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 40 53 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 SUPERFAMILY SSF88946 4 85 4.71E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 234 5.0E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS08160 c9f15c4bcd38ca13f25e8ad799ea0b27 244 Gene3D G3DSA:1.10.10.10 178 240 4.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 Gene3D G3DSA:1.10.287.950 321 517 1.9E-49 T 28-03-2018 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 Gene3D G3DSA:1.10.287.950 174 320 3.1E-20 T 28-03-2018 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 SMART SM00283 266 513 1.6E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 186 2.8E-32 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 Gene3D G3DSA:1.20.120.30 26 173 5.9E-21 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.3E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 SUPERFAMILY SSF58104 233 517 4.84E-78 T 28-03-2018 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.5E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.5E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 42 1.5E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.5E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.5E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 SMART SM00304 213 265 1.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS08590 5c256655134b17b056b418a6acefa345 574 Pfam PF00672 HAMP domain 213 256 5.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Gene3D G3DSA:3.40.250.10 252 367 8.2E-14 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SUPERFAMILY SSF52821 380 531 2.75E-31 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Gene3D G3DSA:3.40.250.10 368 498 6.1E-18 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Gene3D G3DSA:3.40.250.10 13 126 2.1E-14 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SMART SM00450 273 369 0.0015 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SMART SM00450 136 234 2.8E-6 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SMART SM00450 13 110 6.4E-7 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SMART SM00450 384 479 2.1E-5 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SUPERFAMILY SSF52821 259 358 5.63E-18 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SUPERFAMILY SSF52821 20 125 8.91E-21 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Pfam PF00581 Rhodanese-like domain 290 358 1.7E-5 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Pfam PF00581 Rhodanese-like domain 136 230 3.5E-10 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Pfam PF00581 Rhodanese-like domain 389 476 1.4E-5 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Pfam PF00581 Rhodanese-like domain 20 105 7.2E-8 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 SUPERFAMILY SSF52821 111 241 1.2E-30 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS03395 7cb5df5dd68f1b51a530a16451a6ff5e 534 Gene3D G3DSA:3.40.250.10 127 251 1.9E-21 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 Pfam PF02556 Preprotein translocase subunit SecB 8 145 4.1E-54 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 9 145 5.7E-47 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 Gene3D G3DSA:3.10.420.10 4 155 1.6E-50 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 SUPERFAMILY SSF54611 4 145 1.44E-50 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 Hamap MF_00821 Protein-export protein SecB [secB]. 1 151 31.958 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 76 96 2.2E-29 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 16 33 2.2E-29 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 126 144 2.2E-29 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS22595 a193f75891f34f9853e29317501c037c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 100 122 2.2E-29 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 433 443 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 Gene3D G3DSA:2.40.50.140 2 75 9.1E-18 T 28-03-2018 hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 5 451 66.461 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 Gene3D G3DSA:3.40.50.150 76 449 1.8E-52 T 28-03-2018 hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 SUPERFAMILY SSF50249 5 66 1.14E-7 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 SUPERFAMILY SSF53335 69 448 5.67E-77 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS08840 4e73d83bf48f2223cb7a618f17c040b4 452 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 272 444 1.2E-15 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 hmeg3_RS19210 cf70fc6d4d14793cdf2e6572cdc9fa4a 250 Gene3D G3DSA:3.40.50.300 13 250 2.9E-52 T 28-03-2018 hmeg3_RS19210 cf70fc6d4d14793cdf2e6572cdc9fa4a 250 Pfam PF00005 ABC transporter 36 178 2.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19210 cf70fc6d4d14793cdf2e6572cdc9fa4a 250 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19210 cf70fc6d4d14793cdf2e6572cdc9fa4a 250 SUPERFAMILY SSF52540 18 247 6.48E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19210 cf70fc6d4d14793cdf2e6572cdc9fa4a 250 SMART SM00382 43 229 2.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS12055 3105127ecaaca787b2bc8099467dac64 255 Gene3D G3DSA:3.50.30.30 104 247 2.6E-4 T 28-03-2018 hmeg3_RS13840 caf36482e3157d89a8fa3f6ac047ccbb 334 Pfam PF11199 Protein of unknown function (DUF2891) 11 331 5.5E-135 T 28-03-2018 IPR021365 Protein of unknown function DUF2891 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 Pfam PF03466 LysR substrate binding domain 90 294 4.7E-50 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 Gene3D G3DSA:3.40.190.10 179 265 2.2E-19 T 28-03-2018 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 SUPERFAMILY SSF46785 3 111 1.22E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 Gene3D G3DSA:3.40.190.10 89 178 2.1E-22 T 28-03-2018 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 SUPERFAMILY SSF53850 93 295 1.18E-45 T 28-03-2018 hmeg3_RS02690 4801d5afab9bf3cf28fa083512772c27 301 Gene3D G3DSA:1.10.10.10 1 85 5.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19965 a51222c1bbda3d952a611f2faf7d39af 62 Gene3D G3DSA:2.10.70.10 26 61 3.5E-15 T 28-03-2018 hmeg3_RS19965 a51222c1bbda3d952a611f2faf7d39af 62 Pfam PF10636 Hemin uptake protein hemP 26 61 1.3E-14 T 28-03-2018 IPR019600 Hemin uptake protein HemP hmeg3_RS22095 496697eec79b15f943f5151bb79383e6 203 Gene3D G3DSA:1.10.10.60 1 66 8.2E-13 T 28-03-2018 hmeg3_RS22095 496697eec79b15f943f5151bb79383e6 203 SUPERFAMILY SSF48498 93 198 1.63E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS22095 496697eec79b15f943f5151bb79383e6 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 70 1.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS22095 496697eec79b15f943f5151bb79383e6 203 SUPERFAMILY SSF46689 19 80 5.13E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS22095 496697eec79b15f943f5151bb79383e6 203 Gene3D G3DSA:1.10.357.10 67 199 8.8E-14 T 28-03-2018 hmeg3_RS14525 991e8b67694892004152481201ea7427 300 PRINTS PR01270 Histone deacetylase superfamily signature 113 136 8.1E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS14525 991e8b67694892004152481201ea7427 300 PRINTS PR01270 Histone deacetylase superfamily signature 147 162 8.1E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS14525 991e8b67694892004152481201ea7427 300 PRINTS PR01270 Histone deacetylase superfamily signature 221 231 8.1E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS14525 991e8b67694892004152481201ea7427 300 Pfam PF00850 Histone deacetylase domain 33 278 1.8E-52 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS14525 991e8b67694892004152481201ea7427 300 Gene3D G3DSA:3.40.800.20 3 297 2.0E-68 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS14525 991e8b67694892004152481201ea7427 300 SUPERFAMILY SSF52768 4 286 7.67E-81 T 28-03-2018 hmeg3_RS08515 c9c8becb19b37c8438526c2f9dbdbd3b 243 Gene3D G3DSA:3.90.550.10 5 243 2.3E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS08515 c9c8becb19b37c8438526c2f9dbdbd3b 243 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 114 121 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 hmeg3_RS08515 c9c8becb19b37c8438526c2f9dbdbd3b 243 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 14 239 1.6E-67 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 hmeg3_RS08515 c9c8becb19b37c8438526c2f9dbdbd3b 243 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 14 240 1.7E-64 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 hmeg3_RS08515 c9c8becb19b37c8438526c2f9dbdbd3b 243 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 11 239 41.447 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 hmeg3_RS08515 c9c8becb19b37c8438526c2f9dbdbd3b 243 SUPERFAMILY SSF53448 13 240 3.6E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS19095 41c59ad1db8114748b22b7b410e121af 299 Gene3D G3DSA:1.10.3720.10 12 286 9.1E-40 T 28-03-2018 hmeg3_RS19095 41c59ad1db8114748b22b7b410e121af 299 SUPERFAMILY SSF161098 21 299 5.05E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19095 41c59ad1db8114748b22b7b410e121af 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 9.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 14 386 1.4E-92 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 Gene3D G3DSA:3.50.50.60 2 387 7.1E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 SUPERFAMILY SSF51905 12 185 1.23E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 SUPERFAMILY SSF51905 276 377 1.23E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 Pfam PF01494 FAD binding domain 13 325 4.4E-16 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 3.5E-15 T 28-03-2018 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 3.5E-15 T 28-03-2018 hmeg3_RS19930 b8682e18b06b76d384478c424464f2f5 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 3.5E-15 T 28-03-2018 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 SUPERFAMILY SSF102114 56 318 1.15E-66 T 28-03-2018 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 SMART SM00729 87 296 2.2E-19 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 Hamap MF_00206 Lipoyl synthase [lipA]. 1 323 152.821 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 Gene3D G3DSA:3.20.20.70 42 319 7.7E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 TIGRFAM TIGR00510 lipA: lipoyl synthase 36 317 1.6E-127 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 Pfam PF04055 Radical SAM superfamily 94 253 4.0E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS24075 0e4d6ab8fac47108da0f553dd3702c1f 323 PIRSF PIRSF005963 3 322 1.1E-127 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 hmeg3_RS17485 edd897732364068695f32e71b5a84cbe 356 Gene3D G3DSA:1.10.1530.10 9 85 8.1E-24 T 28-03-2018 hmeg3_RS17485 edd897732364068695f32e71b5a84cbe 356 Gene3D G3DSA:3.30.1370.60 86 315 7.6E-65 T 28-03-2018 hmeg3_RS17485 edd897732364068695f32e71b5a84cbe 356 SUPERFAMILY SSF89733 11 350 9.55E-89 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 hmeg3_RS17485 edd897732364068695f32e71b5a84cbe 356 Pfam PF02615 Malate/L-lactate dehydrogenase 12 339 3.7E-92 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 Pfam PF08376 Nitrate and nitrite sensing 59 293 5.2E-12 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 407 436 2.1E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 484 511 2.1E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 513 542 2.1E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 Gene3D G3DSA:1.10.287.950 452 630 7.8E-39 T 28-03-2018 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 Gene3D G3DSA:1.10.287.950 59 451 1.0E-10 T 28-03-2018 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 SUPERFAMILY SSF58104 361 627 1.22E-51 T 28-03-2018 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 SMART SM00283 393 626 3.9E-49 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06070 1d8fdb76cfadda233e8d2c89ffbb1ddc 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 453 613 1.8E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04990 39eb370284d089b5c3f62e53c3f6db41 127 Gene3D G3DSA:3.10.450.50 2 120 1.2E-16 T 28-03-2018 hmeg3_RS04990 39eb370284d089b5c3f62e53c3f6db41 127 Pfam PF12680 SnoaL-like domain 8 109 7.0E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS04990 39eb370284d089b5c3f62e53c3f6db41 127 SUPERFAMILY SSF54427 3 118 4.16E-17 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS16750 32e4b87cb416e85f1af78ad9728569bd 363 Pfam PF02504 Fatty acid synthesis protein 3 330 1.1E-109 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 hmeg3_RS16750 32e4b87cb416e85f1af78ad9728569bd 363 PIRSF PIRSF002465 1 343 5.0E-130 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 hmeg3_RS16750 32e4b87cb416e85f1af78ad9728569bd 363 Gene3D G3DSA:3.40.718.10 1 340 3.6E-108 T 28-03-2018 hmeg3_RS16750 32e4b87cb416e85f1af78ad9728569bd 363 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 341 2.5E-114 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 hmeg3_RS16750 32e4b87cb416e85f1af78ad9728569bd 363 SUPERFAMILY SSF53659 3 339 3.33E-104 T 28-03-2018 hmeg3_RS16750 32e4b87cb416e85f1af78ad9728569bd 363 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 343 155.553 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 PIRSF PIRSF019404 1 146 7.1E-49 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 140 2.7E-29 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 PRINTS PR01004 Flagellar FliJ protein signature 126 146 5.2E-13 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 PRINTS PR01004 Flagellar FliJ protein signature 108 126 5.2E-13 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 PRINTS PR01004 Flagellar FliJ protein signature 44 61 5.2E-13 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 PRINTS PR01004 Flagellar FliJ protein signature 4 26 5.2E-13 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 PRINTS PR01004 Flagellar FliJ protein signature 63 84 5.2E-13 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08300 2494f683c1dfe0b84257671b2cc8ae96 146 Pfam PF02050 Flagellar FliJ protein 19 140 2.3E-31 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 Gene3D G3DSA:3.30.450.20 148 266 1.8E-12 T 28-03-2018 hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 Pfam PF02743 Cache domain 22 252 6.1E-13 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 SUPERFAMILY SSF55073 311 469 1.65E-44 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 Pfam PF00990 Diguanylate cyclase, GGDEF domain 308 466 3.1E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 SMART SM00267 295 470 8.5E-63 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 Gene3D G3DSA:3.30.450.20 19 147 1.2E-7 T 28-03-2018 hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 Gene3D G3DSA:3.30.70.270 290 471 1.3E-50 T 28-03-2018 hmeg3_RS18745 8e23b58244f1eb06f78754dd68fd1b9d 477 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 303 469 6.8E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 Pfam PF03466 LysR substrate binding domain 89 290 2.0E-40 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 Gene3D G3DSA:1.10.10.10 3 82 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 SUPERFAMILY SSF53850 90 293 3.62E-41 T 28-03-2018 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 Gene3D G3DSA:3.40.190.10 88 176 4.5E-15 T 28-03-2018 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 Gene3D G3DSA:3.40.190.10 177 263 4.2E-18 T 28-03-2018 hmeg3_RS04115 3c6c25b20baf5217c9d012f01b557be2 304 SUPERFAMILY SSF46785 6 85 1.41E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22065 a9af0f4eb713bf6856a52e5ea2bf57df 255 SUPERFAMILY SSF56529 1 252 1.57E-41 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS22065 a9af0f4eb713bf6856a52e5ea2bf57df 255 Gene3D G3DSA:3.90.850.10 1 255 1.8E-19 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 SUPERFAMILY SSF52768 14 309 8.82E-102 T 28-03-2018 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 Pfam PF00491 Arginase family 36 307 4.7E-90 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 PRINTS PR00116 Arginase signature 235 264 1.1E-13 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 PRINTS PR00116 Arginase signature 122 137 1.1E-13 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 PIRSF PIRSF036979 16 313 2.5E-100 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 Gene3D G3DSA:3.40.800.10 10 314 1.5E-100 T 28-03-2018 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 TIGRFAM TIGR01230 agmatinase: agmatinase 39 308 1.8E-65 T 28-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 hmeg3_RS23440 555411ee512369094b82cee41e8e278d 317 ProSitePatterns PS01053 Arginase family signature. 238 259 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 hmeg3_RS11435 d7920834381b5ab9c3ea71b046e1f8f9 264 Gene3D G3DSA:3.20.20.450 22 257 1.3E-54 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11435 d7920834381b5ab9c3ea71b046e1f8f9 264 SMART SM00052 24 255 2.0E-36 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11435 d7920834381b5ab9c3ea71b046e1f8f9 264 SUPERFAMILY SSF141868 33 250 1.05E-58 T 28-03-2018 IPR001633 EAL domain hmeg3_RS11435 d7920834381b5ab9c3ea71b046e1f8f9 264 Pfam PF00563 EAL domain 33 250 2.7E-47 T 28-03-2018 IPR001633 EAL domain hmeg3_RS02395 7d44da19f1d4e8fc690b42eb845a029c 373 SMART SM00382 39 226 6.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02395 7d44da19f1d4e8fc690b42eb845a029c 373 Pfam PF13401 AAA domain 39 205 1.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02395 7d44da19f1d4e8fc690b42eb845a029c 373 Gene3D G3DSA:3.40.50.300 3 250 7.9E-13 T 28-03-2018 hmeg3_RS02395 7d44da19f1d4e8fc690b42eb845a029c 373 SMART SM00487 21 233 0.0067 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS02395 7d44da19f1d4e8fc690b42eb845a029c 373 SUPERFAMILY SSF52540 5 105 2.07E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02395 7d44da19f1d4e8fc690b42eb845a029c 373 SUPERFAMILY SSF52540 145 302 2.07E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24525 279edca412cb49f660febb43d8fd79c8 301 SUPERFAMILY SSF161098 21 295 5.76E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24525 279edca412cb49f660febb43d8fd79c8 301 Gene3D G3DSA:1.10.3720.10 24 300 3.2E-51 T 28-03-2018 hmeg3_RS24525 279edca412cb49f660febb43d8fd79c8 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 297 5.6E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 1.1E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 321 1.2E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 Gene3D G3DSA:3.40.50.300 6 335 1.4E-74 T 28-03-2018 hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 Pfam PF00005 ABC transporter 30 187 7.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 SMART SM00382 38 245 2.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11095 00bd71d0efa92d3e4f29b3f92392162d 338 SUPERFAMILY SSF52540 10 258 7.99E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS22615 9b9224d556140534814288612d3885b8 210 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 13 210 21.507 T 28-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 hmeg3_RS22615 9b9224d556140534814288612d3885b8 210 Pfam PF01794 Ferric reductase like transmembrane component 58 168 5.8E-18 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 Pfam PF04982 HPP family 55 175 5.5E-42 T 28-03-2018 IPR007065 HPP hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 Pfam PF00571 CBS domain 328 382 3.3E-10 T 28-03-2018 IPR000644 CBS domain hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 Pfam PF00571 CBS domain 245 296 7.0E-11 T 28-03-2018 IPR000644 CBS domain hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 Gene3D G3DSA:3.10.580.10 230 322 3.4E-16 T 28-03-2018 hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 Gene3D G3DSA:3.10.580.10 323 396 1.1E-10 T 28-03-2018 hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 SMART SM00116 251 299 1.2E-9 T 28-03-2018 IPR000644 CBS domain hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 SMART SM00116 335 383 3.0E-5 T 28-03-2018 IPR000644 CBS domain hmeg3_RS16780 433752da3ec4265dea1a52804258695a 399 SUPERFAMILY SSF54631 232 384 3.37E-35 T 28-03-2018 hmeg3_RS05755 3fdbb9e9b23876ce5a26ab8cd22a863e 137 Pfam PF01042 Endoribonuclease L-PSP 26 134 1.8E-18 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS05755 3fdbb9e9b23876ce5a26ab8cd22a863e 137 SUPERFAMILY SSF55298 19 136 6.28E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS05755 3fdbb9e9b23876ce5a26ab8cd22a863e 137 Gene3D G3DSA:3.30.1330.40 18 137 1.3E-24 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS11045 0d071ed1ea45cdead59fcb232e066c5b 393 Gene3D G3DSA:3.40.190.10 115 306 8.2E-27 T 28-03-2018 hmeg3_RS11045 0d071ed1ea45cdead59fcb232e066c5b 393 Pfam PF13416 Bacterial extracellular solute-binding protein 44 312 2.5E-17 T 28-03-2018 hmeg3_RS11045 0d071ed1ea45cdead59fcb232e066c5b 393 SUPERFAMILY SSF53850 2 381 7.03E-42 T 28-03-2018 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 8.1E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.6E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 SUPERFAMILY SSF50447 207 303 1.71E-27 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Gene3D G3DSA:3.40.50.300 75 205 2.0E-30 T 28-03-2018 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Pfam PF03144 Elongation factor Tu domain 2 227 295 2.0E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Gene3D G3DSA:2.40.30.10 302 395 3.5E-32 T 28-03-2018 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 6.4E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Gene3D G3DSA:2.40.30.10 208 301 1.9E-28 T 28-03-2018 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 SUPERFAMILY SSF50465 304 396 1.58E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.378 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.7E-226 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 Gene3D G3DSA:3.40.50.300 2 74 2.2E-10 T 28-03-2018 hmeg3_RS22945 ec8057b2fdb7ef31b81bcab774937057 398 SUPERFAMILY SSF52540 5 221 9.26E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 Pfam PF12729 Four helix bundle sensory module for signal transduction 11 192 7.8E-12 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 339 491 4.2E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 SMART SM00283 279 526 4.9E-81 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 Gene3D G3DSA:1.10.287.950 38 333 9.6E-12 T 28-03-2018 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 Gene3D G3DSA:1.10.287.950 334 530 4.7E-45 T 28-03-2018 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 1.1E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 1.1E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 454 483 1.1E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 404 1.1E-52 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05385 6e83a23e79f3d754e4bf315ae6fb76ab 571 SUPERFAMILY SSF58104 262 527 6.1E-64 T 28-03-2018 hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 Pfam PF12802 MarR family 40 95 1.0E-12 T 28-03-2018 hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 Gene3D G3DSA:1.10.10.10 1 150 4.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 4.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 4.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 4.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 SUPERFAMILY SSF46785 6 146 8.69E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14190 719335e2b40ddd5ee565b86beb9cb40c 150 SMART SM00347 31 131 5.9E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS07865 c02bfc9aafdd3259b41b16bd8361136e 303 Gene3D G3DSA:3.30.1950.10 59 121 5.7E-15 T 28-03-2018 hmeg3_RS07865 c02bfc9aafdd3259b41b16bd8361136e 303 Gene3D G3DSA:3.10.560.10 225 301 2.5E-14 T 28-03-2018 hmeg3_RS07865 c02bfc9aafdd3259b41b16bd8361136e 303 Pfam PF02563 Polysaccharide biosynthesis/export protein 52 126 8.8E-19 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 hmeg3_RS07865 c02bfc9aafdd3259b41b16bd8361136e 303 Pfam PF10531 SLBB domain 133 180 7.8E-11 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS07865 c02bfc9aafdd3259b41b16bd8361136e 303 Pfam PF10531 SLBB domain 229 272 2.5E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS07865 c02bfc9aafdd3259b41b16bd8361136e 303 Gene3D G3DSA:3.10.560.10 122 224 6.0E-23 T 28-03-2018 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 590 611 1.7E-8 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 SUPERFAMILY SSF52540 370 611 6.36E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Pfam PF00005 ABC transporter 645 788 3.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Pfam PF00005 ABC transporter 388 540 1.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Gene3D G3DSA:3.40.50.300 626 861 1.2E-53 T 28-03-2018 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 ProSitePatterns PS00211 ABC transporters family signature. 761 775 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Gene3D G3DSA:1.10.3470.10 38 329 3.4E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 318 4.4E-42 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 Gene3D G3DSA:3.40.50.300 355 625 1.2E-50 T 28-03-2018 hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 SUPERFAMILY SSF52540 630 855 2.13E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 SMART SM00382 654 837 2.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06015 9a7c83e91ef312f942742f28e9add984 861 SMART SM00382 395 589 7.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06010 cbac322d6372ebff03a74958768b461e 292 Gene3D G3DSA:1.10.3470.10 1 279 4.0E-47 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS06010 cbac322d6372ebff03a74958768b461e 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 276 4.6E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 Gene3D G3DSA:3.30.450.20 28 197 2.5E-21 T 28-03-2018 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 Gene3D G3DSA:1.10.287.130 321 438 1.8E-11 T 28-03-2018 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 Gene3D G3DSA:3.30.565.10 439 602 2.0E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 SMART SM00387 487 604 1.6E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 SMART SM00388 378 446 1.3E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 582 7.8E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 601 7.8E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 561 7.8E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 547 7.8E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 378 443 2.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 Pfam PF02743 Cache domain 40 273 4.9E-12 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 487 601 9.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 SUPERFAMILY SSF103190 53 194 2.35E-16 T 28-03-2018 IPR029151 Periplasmic sensor domain-like hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 SUPERFAMILY SSF55874 441 601 1.44E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 SUPERFAMILY SSF47384 375 443 1.24E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS07410 a32afcd839397330f83e63bae537d31f 605 PIRSF PIRSF036431 1 605 1.2E-189 T 28-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) hmeg3_RS16020 53fa3d309e109ecd395d9d0fcc396325 221 SUPERFAMILY SSF55811 47 212 1.35E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS16020 53fa3d309e109ecd395d9d0fcc396325 221 Gene3D G3DSA:3.90.79.10 25 220 2.2E-39 T 28-03-2018 hmeg3_RS16020 53fa3d309e109ecd395d9d0fcc396325 221 Pfam PF00293 NUDIX domain 58 142 3.9E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS11870 87a5912f396630da386905a94290019a 161 Gene3D G3DSA:3.30.420.10 3 156 2.9E-4 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS11870 87a5912f396630da386905a94290019a 161 SUPERFAMILY SSF53098 5 153 2.02E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS11870 87a5912f396630da386905a94290019a 161 Pfam PF16473 3' exoribonuclease, RNase T-like 4 152 8.6E-9 T 28-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain hmeg3_RS03330 52841b66ef83ae0c1ce0319d0914c7a1 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 13 290 3.8E-94 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 hmeg3_RS03330 52841b66ef83ae0c1ce0319d0914c7a1 297 Pfam PF01040 UbiA prenyltransferase family 26 272 3.1E-61 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 hmeg3_RS03330 52841b66ef83ae0c1ce0319d0914c7a1 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 10 291 19.262 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 hmeg3_RS03330 52841b66ef83ae0c1ce0319d0914c7a1 297 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 65 87 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 SUPERFAMILY SSF50331 237 365 7.78E-28 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 Gene3D G3DSA:2.40.50.100 240 294 7.1E-9 T 28-03-2018 hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 SMART SM00382 29 212 1.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 Gene3D G3DSA:2.40.50.140 295 349 7.2E-12 T 28-03-2018 hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 Pfam PF00005 ABC transporter 21 162 1.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 Gene3D G3DSA:3.40.50.300 1 239 8.3E-69 T 28-03-2018 hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 SUPERFAMILY SSF52540 4 243 4.03E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11025 d3d889967cf6b301f80b270297095a15 381 Pfam PF08402 TOBE domain 282 357 2.5E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 SUPERFAMILY SSF53850 93 298 1.04E-39 T 28-03-2018 hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 Gene3D G3DSA:3.40.190.10 180 266 3.2E-23 T 28-03-2018 hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 Gene3D G3DSA:1.10.10.10 7 87 2.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 7.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 Gene3D G3DSA:3.40.190.10 89 179 2.3E-17 T 28-03-2018 hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 SUPERFAMILY SSF46785 10 115 1.77E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23780 21fa1a05d8e83ccdd0a7d60b7f044c06 317 Pfam PF03466 LysR substrate binding domain 91 295 2.5E-40 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 Pfam PF08448 PAS fold 17 137 4.8E-9 T 28-03-2018 IPR013656 PAS fold-4 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 Gene3D G3DSA:3.30.565.10 272 441 1.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 SMART SM00388 221 289 9.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 SUPERFAMILY SSF55785 10 136 2.42E-10 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 Gene3D G3DSA:3.30.450.20 10 225 9.1E-20 T 28-03-2018 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 3.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 438 3.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 3.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 439 7.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 Gene3D G3DSA:1.10.287.130 226 271 3.1E-16 T 28-03-2018 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 SUPERFAMILY SSF47384 204 289 3.14E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 287 2.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 SMART SM00091 11 77 6.3E-4 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 SUPERFAMILY SSF55874 278 439 2.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12655 ef10b228d23fd432b9b55d0941cdcda8 441 SMART SM00387 329 441 1.2E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS15970 1d79883ddb51ca83c2c91c2230fe74b8 539 Pfam PF13533 Biotin-lipoyl like 114 161 2.5E-13 T 28-03-2018 hmeg3_RS15970 1d79883ddb51ca83c2c91c2230fe74b8 539 Gene3D G3DSA:1.20.1600.10 38 356 2.2E-22 T 28-03-2018 hmeg3_RS15970 1d79883ddb51ca83c2c91c2230fe74b8 539 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 90 416 2.5E-71 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS15970 1d79883ddb51ca83c2c91c2230fe74b8 539 SUPERFAMILY SSF111369 104 339 1.31E-51 T 28-03-2018 hmeg3_RS14515 b36e77c16e04075609ea2d18448c39d9 264 Gene3D G3DSA:1.10.260.40 1 107 1.3E-17 T 28-03-2018 hmeg3_RS14515 b36e77c16e04075609ea2d18448c39d9 264 Pfam PF13560 Helix-turn-helix domain 11 92 2.2E-17 T 28-03-2018 hmeg3_RS14515 b36e77c16e04075609ea2d18448c39d9 264 SUPERFAMILY SSF47413 37 86 2.34E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS14515 b36e77c16e04075609ea2d18448c39d9 264 SMART SM00530 14 89 5.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS13995 159132de02294742c1e7394203bda572 283 PIRSF PIRSF012318 19 283 1.0E-97 T 28-03-2018 IPR011197 Uncharacterised conserved protein UCP012318 hmeg3_RS13995 159132de02294742c1e7394203bda572 283 SUPERFAMILY SSF47240 86 258 9.96E-18 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS13995 159132de02294742c1e7394203bda572 283 Gene3D G3DSA:1.20.1260.10 85 257 9.8E-43 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS13995 159132de02294742c1e7394203bda572 283 Pfam PF04305 Protein of unknown function (DUF455) 37 279 1.7E-95 T 28-03-2018 IPR007402 Protein of unknown function DUF455 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 Gene3D G3DSA:3.90.1150.10 313 437 1.1E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 Pfam PF00202 Aminotransferase class-III 26 429 5.9E-83 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 Gene3D G3DSA:3.90.1150.10 6 160 6.4E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 Gene3D G3DSA:3.40.640.10 190 312 9.0E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 SUPERFAMILY SSF53383 21 431 1.95E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 PIRSF PIRSF000521 125 432 1.8E-25 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS01805 c2f6f985b12d9e018d0991b869fab2bf 440 PIRSF PIRSF000521 1 129 1.4E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS07915 1334e7150abd2c02136aeec6ad108b08 215 SUPERFAMILY SSF54001 9 215 4.81E-57 T 28-03-2018 hmeg3_RS07915 1334e7150abd2c02136aeec6ad108b08 215 Gene3D G3DSA:3.10.550.10 8 215 1.7E-83 T 28-03-2018 IPR023107 Atu2299-like domain hmeg3_RS07915 1334e7150abd2c02136aeec6ad108b08 215 Pfam PF09641 Protein of unknown function (DUF2026) 11 215 1.5E-80 T 28-03-2018 IPR018599 Protein of unknown function DUF2026 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 176 194 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 136 154 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 49 64 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 34 49 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 119 136 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 202 220 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 97 116 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 PRINTS PR01010 Flagellar P-ring protein signature 266 278 9.5E-74 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 Hamap MF_00416 Flagellar P-ring protein [flgI]. 14 379 37.703 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS08225 9d74e9bcf9af4eb4887fe39242dec6d8 379 Pfam PF02119 Flagellar P-ring protein 34 378 1.3E-132 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 Gene3D G3DSA:1.10.1040.10 175 297 2.8E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 SUPERFAMILY SSF51735 3 163 2.51E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 292 1.8E-32 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 SUPERFAMILY SSF48179 165 294 3.85E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 7.4E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 PIRSF PIRSF000103 1 297 4.7E-79 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 Gene3D G3DSA:3.40.50.720 1 174 6.1E-33 T 28-03-2018 hmeg3_RS15125 193c28559e621a2af333fc45d5971dc6 297 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 7 293 6.3E-125 T 28-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 Gene3D G3DSA:1.20.120.530 84 224 2.3E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 Gene3D G3DSA:1.10.10.10 3 68 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 SMART SM00345 7 66 6.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 SUPERFAMILY SSF48008 88 218 1.86E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 66 2.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 SMART SM00895 91 215 9.1E-19 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 1.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 1.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 SUPERFAMILY SSF46785 6 70 4.44E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00425 c238cfc457b280b7f0c85bfb6b064c0c 227 Pfam PF07729 FCD domain 92 214 5.4E-24 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS12330 4375de7c2af0b8c115da836a8c7ec2ba 287 SUPERFAMILY SSF161098 87 274 1.03E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12330 4375de7c2af0b8c115da836a8c7ec2ba 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 283 4.8E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12330 4375de7c2af0b8c115da836a8c7ec2ba 287 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 36 281 5.9E-93 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 hmeg3_RS12330 4375de7c2af0b8c115da836a8c7ec2ba 287 Gene3D G3DSA:1.10.3720.10 24 276 7.7E-26 T 28-03-2018 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 112 145 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 38 52 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 Gene3D G3DSA:3.30.950.10 157 263 1.8E-21 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 33 260 4.0E-77 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 SUPERFAMILY SSF53790 30 260 3.79E-62 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 Gene3D G3DSA:3.40.1010.10 32 156 1.1E-32 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS15320 83c2f0430ecdfadee6efbc021c877521 263 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 34 240 1.3E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS08565 c5ac7ced6f320392e951d881cf78a8f3 415 Pfam PF13480 Acetyltransferase (GNAT) domain 221 370 2.4E-25 T 28-03-2018 hmeg3_RS08565 c5ac7ced6f320392e951d881cf78a8f3 415 SUPERFAMILY SSF55729 211 384 3.39E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS08565 c5ac7ced6f320392e951d881cf78a8f3 415 Gene3D G3DSA:3.40.630.30 164 379 1.6E-22 T 28-03-2018 hmeg3_RS21680 6a6c5114232ab28d613acd831d231674 464 SUPERFAMILY SSF51261 167 420 3.82E-70 T 28-03-2018 IPR011055 Duplicated hybrid motif hmeg3_RS21680 6a6c5114232ab28d613acd831d231674 464 Gene3D G3DSA:1.10.472.60 63 135 0.0012 T 28-03-2018 hmeg3_RS21680 6a6c5114232ab28d613acd831d231674 464 Gene3D G3DSA:2.70.70.10 274 422 5.3E-41 T 28-03-2018 hmeg3_RS21680 6a6c5114232ab28d613acd831d231674 464 Pfam PF01551 Peptidase family M23 322 418 4.4E-33 T 28-03-2018 IPR016047 Peptidase M23 hmeg3_RS00555 5afc0b6268107ac75db8d1e49dec17b3 587 SMART SM00304 208 260 5.6E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00555 5afc0b6268107ac75db8d1e49dec17b3 587 Gene3D G3DSA:1.10.287.950 4 315 3.6E-21 T 28-03-2018 hmeg3_RS00555 5afc0b6268107ac75db8d1e49dec17b3 587 Gene3D G3DSA:1.10.287.950 316 512 5.2E-48 T 28-03-2018 hmeg3_RS00555 5afc0b6268107ac75db8d1e49dec17b3 587 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 321 476 1.4E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00555 5afc0b6268107ac75db8d1e49dec17b3 587 SMART SM00283 261 508 1.5E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00555 5afc0b6268107ac75db8d1e49dec17b3 587 SUPERFAMILY SSF58104 228 512 1.7E-76 T 28-03-2018 hmeg3_RS17455 aa3d845b2156c9983ad64303f56355d4 293 SUPERFAMILY SSF51735 28 288 1.1E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17455 aa3d845b2156c9983ad64303f56355d4 293 Gene3D G3DSA:3.40.50.720 17 292 4.0E-33 T 28-03-2018 hmeg3_RS17455 aa3d845b2156c9983ad64303f56355d4 293 Pfam PF04321 RmlD substrate binding domain 102 273 2.0E-9 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 hmeg3_RS17455 aa3d845b2156c9983ad64303f56355d4 293 Pfam PF02254 TrkA-N domain 16 68 3.5E-5 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Pfam PF13432 Tetratricopeptide repeat 26 77 1.1E-4 T 28-03-2018 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Pfam PF13432 Tetratricopeptide repeat 118 179 0.0075 T 28-03-2018 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SUPERFAMILY SSF48452 29 215 1.71E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Gene3D G3DSA:1.20.58.280 65 99 2.3E-4 T 28-03-2018 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SMART SM00028 50 83 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SMART SM00028 146 179 0.023 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SMART SM00028 16 49 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SMART SM00028 112 145 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SMART SM00028 180 213 4.0E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Gene3D G3DSA:1.25.40.10 162 370 3.2E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Gene3D G3DSA:1.25.40.10 8 64 4.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Gene3D G3DSA:3.40.50.2000 371 535 3.0E-26 T 28-03-2018 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 SUPERFAMILY SSF53756 267 512 6.28E-22 T 28-03-2018 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Gene3D G3DSA:1.25.40.10 100 161 8.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS10055 46208a4d540f7069fc57619566712d8d 535 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 450 485 5.7E-6 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 hmeg3_RS13105 4ccb32263d5d461f742d7f76ebd65cd0 244 Gene3D G3DSA:3.40.50.360 28 229 3.0E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS13105 4ccb32263d5d461f742d7f76ebd65cd0 244 Pfam PF03358 NADPH-dependent FMN reductase 39 181 7.1E-27 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS13105 4ccb32263d5d461f742d7f76ebd65cd0 244 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 12 230 4.9E-120 T 28-03-2018 IPR014063 Arsenate resistance ArsH hmeg3_RS13105 4ccb32263d5d461f742d7f76ebd65cd0 244 SUPERFAMILY SSF52218 12 231 1.72E-60 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS22070 19f672767de2722ec6ec5065c319be69 637 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 53 178 8.3E-25 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component hmeg3_RS22070 19f672767de2722ec6ec5065c319be69 637 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 218 625 1.3E-95 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit hmeg3_RS22070 19f672767de2722ec6ec5065c319be69 637 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 226 631 6.4E-93 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 hmeg3_RS15440 080172abb54c6ef39cf2ad3f0f769fa6 296 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 254 1.5E-52 T 28-03-2018 hmeg3_RS15440 080172abb54c6ef39cf2ad3f0f769fa6 296 Gene3D G3DSA:3.20.20.60 2 296 1.4E-92 T 28-03-2018 hmeg3_RS15440 080172abb54c6ef39cf2ad3f0f769fa6 296 SUPERFAMILY SSF51621 5 290 1.48E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS15440 080172abb54c6ef39cf2ad3f0f769fa6 296 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 hmeg3_RS15440 080172abb54c6ef39cf2ad3f0f769fa6 296 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 4 292 50.584 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 hmeg3_RS15440 080172abb54c6ef39cf2ad3f0f769fa6 296 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 7 291 2.9E-133 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 hmeg3_RS00280 cca5901c3398b3cdb8fe64490fc52eaa 226 PIRSF PIRSF009467 2 226 3.4E-65 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 hmeg3_RS00280 cca5901c3398b3cdb8fe64490fc52eaa 226 Hamap MF_01385 Urease accessory protein UreF [ureF]. 5 226 31.803 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 hmeg3_RS00280 cca5901c3398b3cdb8fe64490fc52eaa 226 Pfam PF01730 UreF 37 184 7.9E-38 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 hmeg3_RS17900 152eaa7c0299055666c43c2882713d54 414 Gene3D G3DSA:3.40.50.10540 4 414 4.1E-138 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS17900 152eaa7c0299055666c43c2882713d54 414 Pfam PF02515 CoA-transferase family III 10 391 6.1E-115 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 hmeg3_RS17900 152eaa7c0299055666c43c2882713d54 414 SUPERFAMILY SSF89796 7 414 2.09E-127 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS01400 774d30d33f9653fa717c546372e11245 481 SUPERFAMILY SSF51905 9 243 1.73E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS01400 774d30d33f9653fa717c546372e11245 481 Gene3D G3DSA:3.50.50.60 7 198 3.4E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS01400 774d30d33f9653fa717c546372e11245 481 Pfam PF13454 FAD-NAD(P)-binding 12 166 1.9E-30 T 28-03-2018 hmeg3_RS01400 774d30d33f9653fa717c546372e11245 481 Gene3D G3DSA:3.50.50.60 199 469 1.8E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS24190 834277b8038e54fa306ffdc915597a2d 667 Pfam PF13361 UvrD-like helicase C-terminal domain 342 645 8.7E-20 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS24190 834277b8038e54fa306ffdc915597a2d 667 SUPERFAMILY SSF52540 5 433 8.64E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24190 834277b8038e54fa306ffdc915597a2d 667 SUPERFAMILY SSF52540 480 651 8.64E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24190 834277b8038e54fa306ffdc915597a2d 667 Gene3D G3DSA:3.40.50.300 3 296 4.1E-27 T 28-03-2018 hmeg3_RS24190 834277b8038e54fa306ffdc915597a2d 667 Gene3D G3DSA:3.40.50.300 297 667 1.3E-26 T 28-03-2018 hmeg3_RS24190 834277b8038e54fa306ffdc915597a2d 667 Pfam PF13245 AAA domain 11 277 7.9E-15 T 28-03-2018 hmeg3_RS14290 5f8aacc5be03edfd3bb8f6081f5a6fbc 196 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 38 151 3.9E-24 T 28-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS14290 5f8aacc5be03edfd3bb8f6081f5a6fbc 196 SUPERFAMILY SSF48600 43 165 1.17E-20 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS14290 5f8aacc5be03edfd3bb8f6081f5a6fbc 196 Gene3D G3DSA:1.20.59.10 29 125 3.6E-15 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS14290 5f8aacc5be03edfd3bb8f6081f5a6fbc 196 Pfam PF01817 Chorismate mutase type II 42 112 2.5E-8 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS14290 5f8aacc5be03edfd3bb8f6081f5a6fbc 196 SMART SM00830 38 115 3.7E-10 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 hmeg3_RS21730 2d94eda11085cf97f25577318cf9b4fd 217 Gene3D G3DSA:3.40.50.1820 1 192 3.2E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21730 2d94eda11085cf97f25577318cf9b4fd 217 SUPERFAMILY SSF53474 2 190 2.04E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21730 2d94eda11085cf97f25577318cf9b4fd 217 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 190 1.5E-55 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA hmeg3_RS22085 0a788bad06bf4decc1ac87d7e004fd4e 277 SUPERFAMILY SSF51735 16 239 2.67E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS22085 0a788bad06bf4decc1ac87d7e004fd4e 277 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 179 1.3E-20 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS22085 0a788bad06bf4decc1ac87d7e004fd4e 277 Gene3D G3DSA:3.40.50.720 16 240 2.6E-31 T 28-03-2018 hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 Pfam PF00571 CBS domain 80 134 1.7E-10 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 Pfam PF00571 CBS domain 7 60 1.5E-13 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 SUPERFAMILY SSF54631 3 134 8.73E-29 T 28-03-2018 hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 Gene3D G3DSA:3.10.580.10 2 75 7.6E-14 T 28-03-2018 hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 SMART SM00116 13 60 9.1E-10 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 SMART SM00116 87 135 5.8E-6 T 28-03-2018 IPR000644 CBS domain hmeg3_RS19790 7c6e1100174bd1f4ca0f4ee1dea0cb67 141 Gene3D G3DSA:3.10.580.10 76 138 2.9E-13 T 28-03-2018 hmeg3_RS04755 a602a59baa836785ee260485873a0779 136 Gene3D G3DSA:3.40.50.2300 3 136 3.5E-33 T 28-03-2018 hmeg3_RS04755 a602a59baa836785ee260485873a0779 136 SUPERFAMILY SSF52172 9 132 5.27E-35 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS04755 a602a59baa836785ee260485873a0779 136 Pfam PF00072 Response regulator receiver domain 12 124 4.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS04755 a602a59baa836785ee260485873a0779 136 SMART SM00448 10 123 9.7E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS22120 0235c11f69c30cefdb25f753a5976fb1 429 SUPERFAMILY SSF54373 278 374 4.45E-12 T 28-03-2018 hmeg3_RS22120 0235c11f69c30cefdb25f753a5976fb1 429 Pfam PF01266 FAD dependent oxidoreductase 2 411 3.3E-60 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS22120 0235c11f69c30cefdb25f753a5976fb1 429 Gene3D G3DSA:3.50.50.60 1 429 6.5E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS22120 0235c11f69c30cefdb25f753a5976fb1 429 SUPERFAMILY SSF51905 1 54 7.38E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS22120 0235c11f69c30cefdb25f753a5976fb1 429 SUPERFAMILY SSF51905 107 278 7.38E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS22120 0235c11f69c30cefdb25f753a5976fb1 429 SUPERFAMILY SSF51905 374 429 7.38E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PIRSF PIRSF000166 2 303 3.5E-125 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 167 191 - T 28-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 SUPERFAMILY SSF102886 6 303 1.57E-135 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 Gene3D G3DSA:3.40.1500.10 1 303 5.2E-138 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 Pfam PF01218 Coproporphyrinogen III oxidase 11 303 4.4E-130 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 263 289 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 91 115 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 32 48 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 163 192 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 49 70 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 235 262 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 PRINTS PR00073 Coprogen oxidase signature 126 148 1.3E-83 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS18820 0e8cd0ac2a1bdaedc8ab14d201839810 303 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 5 278 54.534 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 hmeg3_RS01035 0de18048b140a2fadad5fbffeb9857e5 292 SUPERFAMILY SSF53474 4 292 1.18E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01035 0de18048b140a2fadad5fbffeb9857e5 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 1.4E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01035 0de18048b140a2fadad5fbffeb9857e5 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.4E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01035 0de18048b140a2fadad5fbffeb9857e5 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 1.4E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01035 0de18048b140a2fadad5fbffeb9857e5 292 Pfam PF00561 alpha/beta hydrolase fold 26 151 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01035 0de18048b140a2fadad5fbffeb9857e5 292 Gene3D G3DSA:3.40.50.1820 1 292 2.2E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 SUPERFAMILY SSF48557 18 451 2.67E-122 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00149 Fumarate lyase superfamily signature 238 265 7.6E-26 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 7.6E-26 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 7.6E-26 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 7.6E-26 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 Pfam PF00206 Lyase 26 306 1.2E-52 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 Gene3D G3DSA:1.20.200.10 113 382 4.0E-81 T 28-03-2018 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 Pfam PF10397 Adenylosuccinate lyase C-terminus 372 448 1.0E-20 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 SMART SM00998 371 450 1.3E-30 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 6.9E-13 T 28-03-2018 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 6.9E-13 T 28-03-2018 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 6.9E-13 T 28-03-2018 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 PRINTS PR00145 Argininosuccinate lyase family signature 238 262 6.9E-13 T 28-03-2018 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 Gene3D G3DSA:1.10.40.30 383 450 3.1E-23 T 28-03-2018 hmeg3_RS16355 c3608248d25c5a808d209a38ca6f4832 458 Gene3D G3DSA:1.10.275.10 11 112 8.8E-19 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS06755 08d0c308ef011e6be04a67a24ef79e78 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 279 1.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS06755 08d0c308ef011e6be04a67a24ef79e78 285 Gene3D G3DSA:1.10.3720.10 40 284 8.3E-22 T 28-03-2018 hmeg3_RS06755 08d0c308ef011e6be04a67a24ef79e78 285 SUPERFAMILY SSF161098 87 268 4.84E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 SUPERFAMILY SSF50465 338 437 2.11E-31 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 SUPERFAMILY SSF52540 19 255 2.37E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 Gene3D G3DSA:2.40.30.10 239 332 6.9E-21 T 28-03-2018 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 PRINTS PR00315 GTP-binding elongation factor signature 101 111 1.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 PRINTS PR00315 GTP-binding elongation factor signature 81 89 1.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 PRINTS PR00315 GTP-binding elongation factor signature 21 34 1.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 PRINTS PR00315 GTP-binding elongation factor signature 163 172 1.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 PRINTS PR00315 GTP-binding elongation factor signature 117 128 1.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 74 89 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 Pfam PF00009 Elongation factor Tu GTP binding domain 20 213 1.3E-35 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 Gene3D G3DSA:2.40.30.10 334 439 3.9E-25 T 28-03-2018 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 20 437 1.9E-166 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 Gene3D G3DSA:3.40.50.300 3 238 1.5E-37 T 28-03-2018 hmeg3_RS15315 2ddd92960d62f64c760cf2ca53249a12 441 SUPERFAMILY SSF50447 241 332 2.5E-21 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS01460 5d9dd31a5315ddbb0f60a00a76b1a133 420 Gene3D G3DSA:3.40.50.2300 187 359 1.7E-34 T 28-03-2018 hmeg3_RS01460 5d9dd31a5315ddbb0f60a00a76b1a133 420 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 58 415 3.3E-161 T 28-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like hmeg3_RS01460 5d9dd31a5315ddbb0f60a00a76b1a133 420 Gene3D G3DSA:3.40.50.2300 48 186 4.3E-22 T 28-03-2018 hmeg3_RS01460 5d9dd31a5315ddbb0f60a00a76b1a133 420 SUPERFAMILY SSF53822 57 406 8.07E-94 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01460 5d9dd31a5315ddbb0f60a00a76b1a133 420 Pfam PF13433 Periplasmic binding protein domain 59 417 1.5E-131 T 28-03-2018 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 SUPERFAMILY SSF52540 285 516 3.94E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 264 0.0031 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 496 523 0.0054 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 Pfam PF00005 ABC transporter 292 445 2.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 Pfam PF00005 ABC transporter 20 175 4.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 Gene3D G3DSA:3.40.50.300 1 261 1.8E-66 T 28-03-2018 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 Gene3D G3DSA:3.40.50.300 264 535 8.9E-75 T 28-03-2018 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 SMART SM00382 300 494 1.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 SMART SM00382 28 225 2.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 SUPERFAMILY SSF52540 3 247 1.13E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS07005 5f63767facdca9f5b88c9ee52811b81b 540 ProSitePatterns PS00211 ABC transporters family signature. 417 431 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 Gene3D G3DSA:1.10.275.10 2 138 1.4E-55 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 462 71.647 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 Pfam PF10415 Fumarase C C-terminus 409 460 4.4E-13 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 2.3E-31 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 2.3E-31 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 2.3E-31 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 2.3E-31 T 28-03-2018 IPR000362 Fumarate lyase family hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 Pfam PF00206 Lyase 12 342 4.7E-95 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 SUPERFAMILY SSF48557 4 459 1.57E-135 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 Gene3D G3DSA:1.10.40.30 418 459 3.0E-13 T 28-03-2018 hmeg3_RS16340 7ca5bb7547e0e1f1792aeb48b9503208 467 Gene3D G3DSA:1.20.200.10 139 417 7.7E-81 T 28-03-2018 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 PRINTS PR00124 ATP synthase C subunit signature 10 29 5.7E-5 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 PRINTS PR00124 ATP synthase C subunit signature 31 46 5.7E-5 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 PRINTS PR00124 ATP synthase C subunit signature 48 73 5.7E-5 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 Gene3D G3DSA:1.20.20.10 3 75 1.2E-15 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 Pfam PF00137 ATP synthase subunit C 9 71 4.9E-11 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 2.6E-22 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 SUPERFAMILY SSF81333 4 77 5.89E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 hmeg3_RS02420 7adba98cb960c6a00bbaeaf12689f394 81 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 14.343 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 Pfam PF01546 Peptidase family M20/M25/M40 95 416 3.2E-24 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 Pfam PF07687 Peptidase dimerisation domain 206 316 1.8E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 SUPERFAMILY SSF53187 333 420 3.55E-46 T 28-03-2018 hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 SUPERFAMILY SSF53187 13 208 3.55E-46 T 28-03-2018 hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 94 103 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 Gene3D G3DSA:3.40.630.10 1 314 3.8E-52 T 28-03-2018 hmeg3_RS03060 f73cc0539bef082fb683b36546847e91 422 SUPERFAMILY SSF55031 209 316 4.49E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS19745 3639069211f942ed73cad1d30460906a 448 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 218 433 2.8E-49 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 hmeg3_RS19745 3639069211f942ed73cad1d30460906a 448 SMART SM00646 278 433 7.3E-61 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 hmeg3_RS19745 3639069211f942ed73cad1d30460906a 448 Pfam PF11741 AMIN domain 45 148 3.9E-27 T 28-03-2018 IPR021731 AMIN domain hmeg3_RS19745 3639069211f942ed73cad1d30460906a 448 SUPERFAMILY SSF53187 360 436 1.04E-55 T 28-03-2018 hmeg3_RS19745 3639069211f942ed73cad1d30460906a 448 SUPERFAMILY SSF53187 216 312 1.04E-55 T 28-03-2018 hmeg3_RS19745 3639069211f942ed73cad1d30460906a 448 Gene3D G3DSA:3.40.630.40 213 440 4.5E-57 T 28-03-2018 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 592 3.9E-32 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 165 273 8.8E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Gene3D G3DSA:1.10.540.10 10 162 7.8E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 SUPERFAMILY SSF47203 289 469 1.27E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Gene3D G3DSA:1.20.140.10 278 469 5.3E-43 T 28-03-2018 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 4.5E-13 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 82 160 8.7E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 SUPERFAMILY SSF56645 40 282 3.53E-56 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 453 4.6E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS22355 a418e2770c85d25b6573120c8c86ba4b 596 Gene3D G3DSA:2.40.110.10 163 276 1.4E-21 T 28-03-2018 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 TIGRFAM TIGR01404 FlhB_rel_III: type III secretion protein, YscU/HrpY family 4 339 2.6E-110 T 28-03-2018 IPR006307 Type III exporter system, secretion apparatus protein BsaZ GO:0009306|GO:0016021 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 197 215 4.7E-33 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 6 28 4.7E-33 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 261 276 4.7E-33 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 217 234 4.7E-33 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 291 312 4.7E-33 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 Gene3D G3DSA:3.40.1690.10 207 342 3.4E-38 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 SUPERFAMILY SSF160544 233 340 1.02E-25 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal hmeg3_RS15785 a6204339da0aec65814aa3d2e97a224f 364 Pfam PF01312 FlhB HrpN YscU SpaS Family 4 335 7.0E-87 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS21930 a4361a798139cc5a84edf5dd36701db6 62 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 1 58 19.381 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 hmeg3_RS21930 a4361a798139cc5a84edf5dd36701db6 62 Gene3D G3DSA:3.30.50.10 1 59 5.2E-25 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 hmeg3_RS21930 a4361a798139cc5a84edf5dd36701db6 62 Pfam PF03884 DNA gyrase inhibitor YacG 5 55 1.1E-26 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 hmeg3_RS21930 a4361a798139cc5a84edf5dd36701db6 62 SUPERFAMILY SSF57716 2 59 3.85E-22 T 28-03-2018 hmeg3_RS03165 abfc98feee5e2450a7e01d8213a7aca2 385 Pfam PF13458 Periplasmic binding protein 40 378 1.7E-50 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS03165 abfc98feee5e2450a7e01d8213a7aca2 385 Gene3D G3DSA:3.40.50.2300 23 174 2.0E-19 T 28-03-2018 hmeg3_RS03165 abfc98feee5e2450a7e01d8213a7aca2 385 SUPERFAMILY SSF53822 40 383 5.65E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS03165 abfc98feee5e2450a7e01d8213a7aca2 385 Gene3D G3DSA:3.40.50.2300 199 373 1.4E-18 T 28-03-2018 hmeg3_RS02000 e6805280474164d1ccad32703c5edb4f 131 Gene3D G3DSA:3.30.1130.10 2 131 1.5E-30 T 28-03-2018 hmeg3_RS02000 e6805280474164d1ccad32703c5edb4f 131 TIGRFAM TIGR00526 folB_dom: FolB domain 15 126 4.8E-15 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 hmeg3_RS02000 e6805280474164d1ccad32703c5edb4f 131 SMART SM00905 15 126 2.4E-27 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 hmeg3_RS02000 e6805280474164d1ccad32703c5edb4f 131 Pfam PF02152 Dihydroneopterin aldolase 15 124 1.6E-23 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 hmeg3_RS02000 e6805280474164d1ccad32703c5edb4f 131 SUPERFAMILY SSF55620 11 126 7.23E-28 T 28-03-2018 hmeg3_RS00320 7fab8bf27a40d608c34b9dbfa5ff19f3 374 Gene3D G3DSA:1.10.3470.10 43 362 2.6E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS00320 7fab8bf27a40d608c34b9dbfa5ff19f3 374 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 43 357 3.3E-137 T 28-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC hmeg3_RS00320 7fab8bf27a40d608c34b9dbfa5ff19f3 374 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 346 3.2E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05030 236fff0ebd58a289adb33c0071ce04d7 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3 335 1.8E-132 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 hmeg3_RS05030 236fff0ebd58a289adb33c0071ce04d7 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 2 336 46.615 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 hmeg3_RS05030 236fff0ebd58a289adb33c0071ce04d7 342 Pfam PF02547 Queuosine biosynthesis protein 4 335 4.6E-134 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 hmeg3_RS05030 236fff0ebd58a289adb33c0071ce04d7 342 SUPERFAMILY SSF111337 5 335 3.4E-133 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 hmeg3_RS05030 236fff0ebd58a289adb33c0071ce04d7 342 Gene3D G3DSA:3.40.1780.10 170 336 5.4E-68 T 28-03-2018 hmeg3_RS05030 236fff0ebd58a289adb33c0071ce04d7 342 Gene3D G3DSA:3.40.1780.10 1 111 1.3E-28 T 28-03-2018 hmeg3_RS24175 b91032be75ffe82bcc8d4d81fe50da4c 219 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 22 215 27.631 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 hmeg3_RS24175 b91032be75ffe82bcc8d4d81fe50da4c 219 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 34 217 8.2E-54 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 hmeg3_RS24175 b91032be75ffe82bcc8d4d81fe50da4c 219 SUPERFAMILY SSF53335 17 218 3.56E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS24175 b91032be75ffe82bcc8d4d81fe50da4c 219 PIRSF PIRSF003078 8 219 8.8E-56 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 hmeg3_RS24175 b91032be75ffe82bcc8d4d81fe50da4c 219 Pfam PF02527 rRNA small subunit methyltransferase G 29 213 7.3E-56 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 hmeg3_RS24175 b91032be75ffe82bcc8d4d81fe50da4c 219 Gene3D G3DSA:3.40.50.150 2 219 1.5E-32 T 28-03-2018 hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 SUPERFAMILY SSF102405 91 297 5.04E-43 T 28-03-2018 hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 80 297 2.3E-81 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 Gene3D G3DSA:1.10.150.20 2 68 0.0015 T 28-03-2018 hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 Gene3D G3DSA:3.40.50.450 121 270 8.9E-38 T 28-03-2018 hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 SUPERFAMILY SSF47781 11 65 3.95E-5 T 28-03-2018 IPR010994 RuvA domain 2-like hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 Gene3D G3DSA:1.10.10.10 281 387 4.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00635 8d8180098909232d082035ac8167f267 390 Pfam PF02481 DNA recombination-mediator protein A 83 288 1.2E-77 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 hmeg3_RS15450 e0c616e49d30298ed42997c12c3b216a 430 Pfam PF07690 Major Facilitator Superfamily 56 375 5.2E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS15450 e0c616e49d30298ed42997c12c3b216a 430 SUPERFAMILY SSF103473 21 424 5.62E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS15450 e0c616e49d30298ed42997c12c3b216a 430 ProSitePatterns PS00216 Sugar transport proteins signature 1. 84 100 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS15450 e0c616e49d30298ed42997c12c3b216a 430 Gene3D G3DSA:1.20.1250.20 230 428 3.1E-23 T 28-03-2018 hmeg3_RS15450 e0c616e49d30298ed42997c12c3b216a 430 Gene3D G3DSA:1.20.1250.20 15 229 5.4E-23 T 28-03-2018 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 Gene3D G3DSA:3.40.190.10 172 266 2.7E-16 T 28-03-2018 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 SUPERFAMILY SSF46785 4 82 1.24E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 Pfam PF03466 LysR substrate binding domain 88 295 6.4E-31 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 Gene3D G3DSA:3.40.190.10 89 171 1.8E-6 T 28-03-2018 hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 Gene3D G3DSA:1.10.10.10 2 84 7.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23500 b0fbdecc44a397c78506ed3936d3b594 311 SUPERFAMILY SSF53850 88 298 8.07E-35 T 28-03-2018 hmeg3_RS22290 0d960f6e0aa36501ba422865662c47af 253 SUPERFAMILY SSF54197 31 252 4.08E-68 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 hmeg3_RS22290 0d960f6e0aa36501ba422865662c47af 253 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 31 252 3.7E-79 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 hmeg3_RS22290 0d960f6e0aa36501ba422865662c47af 253 Gene3D G3DSA:3.30.428.30 29 251 1.5E-75 T 28-03-2018 hmeg3_RS22290 0d960f6e0aa36501ba422865662c47af 253 PIRSF PIRSF001273 5 253 3.1E-65 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 hmeg3_RS05775 b008add190a3b0c3152a820a097a243a 313 Pfam PF00850 Histone deacetylase domain 20 309 3.0E-79 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS05775 b008add190a3b0c3152a820a097a243a 313 SUPERFAMILY SSF52768 1 311 3.07E-101 T 28-03-2018 hmeg3_RS05775 b008add190a3b0c3152a820a097a243a 313 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 6.5E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS05775 b008add190a3b0c3152a820a097a243a 313 PRINTS PR01270 Histone deacetylase superfamily signature 127 150 6.5E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS05775 b008add190a3b0c3152a820a097a243a 313 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 6.5E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS05775 b008add190a3b0c3152a820a097a243a 313 Gene3D G3DSA:3.40.800.20 1 313 8.8E-108 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 49 290 1.0E-48 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 Gene3D G3DSA:2.30.30.100 243 290 2.8E-12 T 28-03-2018 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 SUPERFAMILY SSF55681 46 241 4.77E-46 T 28-03-2018 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 Pfam PF02237 Biotin protein ligase C terminal domain 245 290 4.7E-9 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 162 9.5E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 Gene3D G3DSA:3.30.930.10 16 242 9.1E-55 T 28-03-2018 hmeg3_RS02800 61d60b55203593dba3292689de694d07 293 SUPERFAMILY SSF50037 243 290 1.46E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal hmeg3_RS02720 856bade2c5f3ce952c95f20178a90f74 359 SUPERFAMILY SSF50331 247 332 1.59E-6 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS02720 856bade2c5f3ce952c95f20178a90f74 359 Pfam PF00005 ABC transporter 23 171 8.9E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS02720 856bade2c5f3ce952c95f20178a90f74 359 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS02720 856bade2c5f3ce952c95f20178a90f74 359 Gene3D G3DSA:3.40.50.300 1 261 4.1E-71 T 28-03-2018 hmeg3_RS02720 856bade2c5f3ce952c95f20178a90f74 359 SMART SM00382 32 221 6.5E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02720 856bade2c5f3ce952c95f20178a90f74 359 SUPERFAMILY SSF52540 4 253 5.2E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02990 6adde3900381b501e53e897bcc55cdbd 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 279 9.3E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS02990 6adde3900381b501e53e897bcc55cdbd 306 Gene3D G3DSA:1.10.3470.10 1 289 2.0E-38 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 32 405 1.1E-112 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 25 437 37.024 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 217 240 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 140 159 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 349 366 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 165 186 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 381 400 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 112 138 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 321 340 1.8E-54 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS13420 1c1f109c0335aae47e789945266ca82a 438 Pfam PF01566 Natural resistance-associated macrophage protein 53 410 7.8E-133 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS00525 8f25d582e3e0b5ac3e12d280c408a3fb 219 TIGRFAM TIGR00277 HDIG: HDIG domain 48 136 1.0E-8 T 28-03-2018 IPR006675 HDIG domain hmeg3_RS00525 8f25d582e3e0b5ac3e12d280c408a3fb 219 SUPERFAMILY SSF109604 28 206 3.35E-33 T 28-03-2018 hmeg3_RS00525 8f25d582e3e0b5ac3e12d280c408a3fb 219 Pfam PF13487 HD domain 97 159 6.3E-22 T 28-03-2018 hmeg3_RS00525 8f25d582e3e0b5ac3e12d280c408a3fb 219 SMART SM00471 42 177 1.8E-7 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS00525 8f25d582e3e0b5ac3e12d280c408a3fb 219 Gene3D G3DSA:1.10.3210.10 21 213 3.2E-47 T 28-03-2018 hmeg3_RS23250 b854174d1db403132d067c1ad50fa7b3 190 Pfam PF05962 HutD 9 174 3.5E-50 T 28-03-2018 IPR010282 Uncharacterised protein family HutD/Ves hmeg3_RS23250 b854174d1db403132d067c1ad50fa7b3 190 Gene3D G3DSA:2.60.120.10 7 109 7.8E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS23250 b854174d1db403132d067c1ad50fa7b3 190 Gene3D G3DSA:2.60.120.10 110 186 2.7E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS23250 b854174d1db403132d067c1ad50fa7b3 190 SUPERFAMILY SSF51182 3 185 3.69E-51 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 SMART SM00448 3 114 2.9E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 162 182 3.4E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 145 162 3.4E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 SUPERFAMILY SSF52172 6 160 5.12E-27 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 Gene3D G3DSA:3.40.50.2300 2 132 8.1E-26 T 28-03-2018 hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 Pfam PF02954 Bacterial regulatory protein, Fis family 139 178 2.1E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 Pfam PF00072 Response regulator receiver domain 6 114 2.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10350 1195d0703e6998626717075c1ee16b73 183 Gene3D G3DSA:1.10.10.60 134 182 1.6E-14 T 28-03-2018 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 SUPERFAMILY SSF53244 290 431 2.93E-28 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 Gene3D G3DSA:3.40.1190.10 1 289 3.1E-74 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 Pfam PF08245 Mur ligase middle domain 50 264 2.5E-11 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 PIRSF PIRSF001563 2 433 4.2E-102 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 Gene3D G3DSA:3.90.190.20 290 435 2.8E-26 T 28-03-2018 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 TIGRFAM TIGR01499 folC: bifunctional protein FolC 36 428 6.2E-100 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 SUPERFAMILY SSF53623 9 286 3.11E-83 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 hmeg3_RS17200 263c1c23eabeb04f8edb7d18fb76eb76 435 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 48 71 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 Gene3D G3DSA:1.10.287.1060 250 332 0.0046 T 28-03-2018 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 487 1.3E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 Pfam PF12729 Four helix bundle sensory module for signal transduction 13 191 3.1E-28 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 SUPERFAMILY SSF58104 240 522 3.79E-78 T 28-03-2018 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 SMART SM00304 220 272 6.6E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 Gene3D G3DSA:1.10.287.950 333 524 2.9E-50 T 28-03-2018 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 SMART SM00283 273 520 1.3E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 Gene3D G3DSA:1.20.120.30 32 194 1.3E-15 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 448 477 7.6E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 7.6E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 7.6E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 294 323 7.6E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS19750 b70330948eaab30c7292985cfd1e56b2 582 Pfam PF00672 HAMP domain 220 268 2.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 Gene3D G3DSA:1.10.10.10 2 73 9.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 TIGRFAM TIGR03338 phnR_burk: phosphonate utilization associated transcriptional regulator 5 215 3.7E-88 T 28-03-2018 IPR017723 Transcription regulator, 2-aminoethylphosphonate utilisation-associated hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 SUPERFAMILY SSF48008 84 219 1.26E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 Pfam PF07729 FCD domain 87 209 1.2E-26 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 SMART SM00345 19 77 1.7E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 77 1.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 SMART SM00895 87 211 6.9E-21 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 SUPERFAMILY SSF46785 10 81 4.78E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09355 baa07ae5752935a220d311699f40b69a 225 Gene3D G3DSA:1.20.120.530 74 224 2.0E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS12025 a6bf4cd933eb18e097b84289eefc05dd 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 273 1.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12025 a6bf4cd933eb18e097b84289eefc05dd 283 Gene3D G3DSA:1.10.3720.10 24 282 2.2E-48 T 28-03-2018 hmeg3_RS12025 a6bf4cd933eb18e097b84289eefc05dd 283 SUPERFAMILY SSF161098 22 278 2.62E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS20835 528fd5253842a537dfbb194ac809807b 413 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 231 389 9.2E-42 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20835 528fd5253842a537dfbb194ac809807b 413 SMART SM00267 222 391 5.8E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20835 528fd5253842a537dfbb194ac809807b 413 Gene3D G3DSA:3.30.70.270 216 392 1.0E-50 T 28-03-2018 hmeg3_RS20835 528fd5253842a537dfbb194ac809807b 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 233 387 3.8E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS20835 528fd5253842a537dfbb194ac809807b 413 SUPERFAMILY SSF55073 238 390 1.49E-41 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 Pfam PF00989 PAS fold 13 125 1.0E-14 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 Gene3D G3DSA:3.30.565.10 239 395 6.6E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 390 2.6E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 SMART SM00387 280 391 4.9E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 Gene3D G3DSA:3.30.450.20 7 179 9.5E-32 T 28-03-2018 hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 SUPERFAMILY SSF55874 261 390 1.11E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 SMART SM00091 9 75 5.0E-9 T 28-03-2018 IPR000014 PAS domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 135 1.2E-16 T 28-03-2018 IPR000014 PAS domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 SUPERFAMILY SSF55785 20 137 1.33E-22 T 28-03-2018 IPR000014 PAS domain hmeg3_RS17385 b576cc5f8aac77a68f026b8f0b7e04c4 395 Pfam PF07730 Histidine kinase 174 239 3.3E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS01560 ebbe811a341af84a27feb4f216100242 148 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 142 1.0E-41 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS01560 ebbe811a341af84a27feb4f216100242 148 PIRSF PIRSF001399 1 146 1.9E-55 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS01560 ebbe811a341af84a27feb4f216100242 148 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 148 57.818 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS01560 ebbe811a341af84a27feb4f216100242 148 SUPERFAMILY SSF52304 5 144 3.66E-52 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS01560 ebbe811a341af84a27feb4f216100242 148 Pfam PF01220 Dehydroquinase class II 5 140 1.1E-50 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS01560 ebbe811a341af84a27feb4f216100242 148 Gene3D G3DSA:3.40.50.9100 1 146 8.6E-56 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 3.8E-9 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 3.8E-9 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.8E-9 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 Gene3D G3DSA:3.40.50.720 155 369 5.3E-29 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.0E-10 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 1.0E-10 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.0E-10 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 1.0E-10 T 28-03-2018 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 323 6.7E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 SUPERFAMILY SSF51905 3 337 1.3E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13845 1668c1f8b6ff80b5ed5628aa92340e4c 428 Gene3D G3DSA:3.50.50.60 1 142 1.7E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS13170 9e080d398c7378625956467b04089865 213 Pfam PF06532 Protein of unknown function (DUF1109) 10 213 6.9E-66 T 28-03-2018 IPR009495 Anti-sigma-F factor NrsF hmeg3_RS17935 6ac3bac587e974c621db16adba21303a 122 SUPERFAMILY SSF160975 22 71 9.68E-16 T 28-03-2018 hmeg3_RS17935 6ac3bac587e974c621db16adba21303a 122 Pfam PF12836 Helix-hairpin-helix motif 23 78 1.7E-10 T 28-03-2018 hmeg3_RS17935 6ac3bac587e974c621db16adba21303a 122 Gene3D G3DSA:1.10.150.310 40 117 1.5E-9 T 28-03-2018 hmeg3_RS17935 6ac3bac587e974c621db16adba21303a 122 Gene3D G3DSA:1.10.150.20 1 39 4.6E-6 T 28-03-2018 hmeg3_RS10235 146be23bb7b85ac1a9935bd00823a794 616 SUPERFAMILY SSF54001 252 373 5.4E-10 T 28-03-2018 hmeg3_RS10235 146be23bb7b85ac1a9935bd00823a794 616 Pfam PF01841 Transglutaminase-like superfamily 258 329 3.6E-8 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS10235 146be23bb7b85ac1a9935bd00823a794 616 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 43 205 4.0E-27 T 28-03-2018 IPR024618 Domain of unknown function DUF3857 hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 SUPERFAMILY SSF52172 4 130 8.11E-41 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 4.0E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 Gene3D G3DSA:1.10.10.10 128 233 3.8E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 SMART SM00448 6 119 1.2E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 Gene3D G3DSA:3.40.50.2300 1 127 2.7E-34 T 28-03-2018 hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 SUPERFAMILY SSF46894 129 227 2.58E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 Pfam PF00072 Response regulator receiver domain 8 120 2.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06560 c75e09f4b340cfd0eb856a73206f08e9 233 SMART SM00862 153 226 3.6E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS11675 43b7f122fbb1dc3e99d7d0a3570be937 439 SUPERFAMILY SSF51905 4 242 1.03E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11675 43b7f122fbb1dc3e99d7d0a3570be937 439 Gene3D G3DSA:3.50.50.60 2 212 4.6E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11675 43b7f122fbb1dc3e99d7d0a3570be937 439 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 2 345 1.6E-123 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase hmeg3_RS11675 43b7f122fbb1dc3e99d7d0a3570be937 439 Gene3D G3DSA:3.50.50.60 213 418 2.6E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11675 43b7f122fbb1dc3e99d7d0a3570be937 439 SUPERFAMILY SSF51905 279 386 9.55E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS11675 43b7f122fbb1dc3e99d7d0a3570be937 439 SUPERFAMILY SSF51905 191 250 9.55E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS20465 281cc40826837087758a9de9a1cb3a4e 282 Gene3D G3DSA:1.10.3720.10 17 281 4.5E-35 T 28-03-2018 hmeg3_RS20465 281cc40826837087758a9de9a1cb3a4e 282 SUPERFAMILY SSF161098 17 271 2.62E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS20465 281cc40826837087758a9de9a1cb3a4e 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 273 8.5E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02280 379379ffc4034abec7053b1d656f88e8 174 Gene3D G3DSA:2.102.10.10 42 174 1.1E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS02280 379379ffc4034abec7053b1d656f88e8 174 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 44 173 9.1E-60 T 28-03-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 hmeg3_RS02280 379379ffc4034abec7053b1d656f88e8 174 Pfam PF00355 Rieske [2Fe-2S] domain 91 146 2.0E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS02280 379379ffc4034abec7053b1d656f88e8 174 Gene3D G3DSA:1.20.5.510 2 29 1.6E-4 T 28-03-2018 hmeg3_RS02280 379379ffc4034abec7053b1d656f88e8 174 SUPERFAMILY SSF50022 46 172 1.44E-26 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS02280 379379ffc4034abec7053b1d656f88e8 174 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 26 8.1E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 308 329 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 Gene3D G3DSA:1.10.4030.10 36 167 1.2E-19 T 28-03-2018 hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 Pfam PF13624 SurA N-terminal domain 1 163 2.2E-43 T 28-03-2018 hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 SUPERFAMILY SSF109998 201 241 1.22E-26 T 28-03-2018 IPR027304 Trigger factor/SurA domain hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 SUPERFAMILY SSF109998 39 167 1.22E-26 T 28-03-2018 IPR027304 Trigger factor/SurA domain hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 SUPERFAMILY SSF54534 260 368 2.22E-33 T 28-03-2018 hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 Gene3D G3DSA:3.10.50.40 258 395 1.9E-42 T 28-03-2018 hmeg3_RS10580 b3e75062c92f9248cea7946612e6920e 648 Pfam PF13616 PPIC-type PPIASE domain 263 368 3.5E-32 T 28-03-2018 hmeg3_RS13155 945468beec9b4b0c8f854816d0140e1d 214 Pfam PF06532 Protein of unknown function (DUF1109) 10 214 3.2E-55 T 28-03-2018 IPR009495 Anti-sigma-F factor NrsF hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Gene3D G3DSA:3.10.50.40 202 321 5.1E-30 T 28-03-2018 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Gene3D G3DSA:3.10.50.40 322 449 4.4E-33 T 28-03-2018 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 SUPERFAMILY SSF54534 323 424 3.92E-31 T 28-03-2018 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 364 384 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Pfam PF00639 PPIC-type PPIASE domain 332 423 2.4E-25 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Pfam PF00639 PPIC-type PPIASE domain 218 311 6.1E-23 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Hamap MF_01183 Chaperone SurA [surA]. 13 470 34.247 T 28-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 SUPERFAMILY SSF109998 64 241 7.06E-41 T 28-03-2018 IPR027304 Trigger factor/SurA domain hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 SUPERFAMILY SSF54534 213 313 1.77E-29 T 28-03-2018 hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Pfam PF09312 SurA N-terminal domain 64 181 4.6E-40 T 28-03-2018 IPR015391 SurA N-terminal hmeg3_RS19905 2f208db9520c655f3f52543ff770e5cf 472 Gene3D G3DSA:1.10.4030.10 60 187 2.6E-24 T 28-03-2018 hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 SMART SM00418 8 89 5.5E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 Gene3D G3DSA:1.10.10.10 2 109 1.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 Pfam PF12840 Helix-turn-helix domain 9 64 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 7.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 7.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 7.3E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 hmeg3_RS07370 fce6622fae828d7a581792e6c5c51d8c 113 SUPERFAMILY SSF46785 1 99 5.46E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14535 83ec68861c6a0e33a91429e5513c62ef 269 SUPERFAMILY SSF53218 2 215 4.45E-35 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS14535 83ec68861c6a0e33a91429e5513c62ef 269 SMART SM00852 4 183 6.6E-36 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS14535 83ec68861c6a0e33a91429e5513c62ef 269 Gene3D G3DSA:3.40.980.10 1 182 1.8E-44 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS14535 83ec68861c6a0e33a91429e5513c62ef 269 Pfam PF00994 Probable molybdopterin binding domain 5 176 5.4E-28 T 28-03-2018 IPR001453 MoaB/Mog domain hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 46 589 2.1E-131 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 Pfam PF08345 Flagellar M-ring protein C-terminal 278 461 1.4E-48 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 Pfam PF01514 Secretory protein of YscJ/FliF family 54 243 5.5E-77 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 PRINTS PR01009 Flagellar M-ring protein signature 144 162 5.1E-39 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 PRINTS PR01009 Flagellar M-ring protein signature 290 308 5.1E-39 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 PRINTS PR01009 Flagellar M-ring protein signature 176 190 5.1E-39 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 PRINTS PR01009 Flagellar M-ring protein signature 385 409 5.1E-39 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 PRINTS PR01009 Flagellar M-ring protein signature 219 237 5.1E-39 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 Gene3D G3DSA:3.30.70.1530 75 138 6.5E-9 T 28-03-2018 hmeg3_RS08320 55f36b9c4207c97ff4749eef2ab85fa7 589 PIRSF PIRSF004862 36 589 3.3E-154 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 Gene3D G3DSA:1.10.10.10 2 90 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 SUPERFAMILY SSF53383 119 479 2.15E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 Gene3D G3DSA:3.40.640.10 136 388 6.2E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 Pfam PF00155 Aminotransferase class I and II 138 478 4.9E-26 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 SUPERFAMILY SSF46785 9 81 1.23E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 SMART SM00345 14 77 3.6E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 1.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS13905 f8ec0ef1cc48ff54c30d5784bfc2b183 487 Gene3D G3DSA:3.90.1150.10 389 484 4.5E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS19845 1208278aa799652f3f82a3e0a205efb0 538 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 34 523 22.034 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 hmeg3_RS19845 1208278aa799652f3f82a3e0a205efb0 538 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 88 485 1.8E-92 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 hmeg3_RS19845 1208278aa799652f3f82a3e0a205efb0 538 SUPERFAMILY SSF56317 246 515 7.33E-33 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS19845 1208278aa799652f3f82a3e0a205efb0 538 Pfam PF00795 Carbon-nitrogen hydrolase 259 510 4.3E-25 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS19845 1208278aa799652f3f82a3e0a205efb0 538 Gene3D G3DSA:3.60.110.10 232 505 6.1E-35 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS19595 a7d04cba5227b6efbcbf857b0c3bc91c 127 Gene3D G3DSA:2.60.40.420 2 127 1.0E-18 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS19595 a7d04cba5227b6efbcbf857b0c3bc91c 127 Pfam PF13473 Cupredoxin-like domain 33 126 4.4E-11 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain hmeg3_RS19595 a7d04cba5227b6efbcbf857b0c3bc91c 127 SUPERFAMILY SSF49503 34 126 1.74E-22 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS01825 a5a4a0e2fd2951703b3d5b60150121c9 245 Gene3D G3DSA:3.40.50.300 1 239 7.0E-70 T 28-03-2018 hmeg3_RS01825 a5a4a0e2fd2951703b3d5b60150121c9 245 SUPERFAMILY SSF52540 1 226 3.33E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01825 a5a4a0e2fd2951703b3d5b60150121c9 245 PIRSF PIRSF039085 1 243 4.1E-95 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS01825 a5a4a0e2fd2951703b3d5b60150121c9 245 Pfam PF00005 ABC transporter 17 165 2.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01825 a5a4a0e2fd2951703b3d5b60150121c9 245 SMART SM00382 26 213 1.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01825 a5a4a0e2fd2951703b3d5b60150121c9 245 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS11035 4d57b922e5a44b37cebdba86ddcb48d3 304 SUPERFAMILY SSF161098 50 286 3.66E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11035 4d57b922e5a44b37cebdba86ddcb48d3 304 Gene3D G3DSA:1.10.3720.10 8 304 6.8E-42 T 28-03-2018 hmeg3_RS11035 4d57b922e5a44b37cebdba86ddcb48d3 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 298 4.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 Gene3D G3DSA:1.20.140.10 230 401 1.2E-14 T 28-03-2018 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 Gene3D G3DSA:1.10.540.10 7 119 1.3E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 Gene3D G3DSA:2.40.110.10 120 223 2.4E-14 T 28-03-2018 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 SUPERFAMILY SSF47203 236 381 1.28E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 PIRSF PIRSF016578 1 82 1.3E-7 T 28-03-2018 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 PIRSF PIRSF016578 125 399 4.0E-20 T 28-03-2018 hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 243 377 3.0E-8 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain hmeg3_RS21000 7b2ec40b059105afdc947171f6829b2d 405 SUPERFAMILY SSF56645 13 219 1.7E-35 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS07510 63792a84df4bc34f3a372977569b6d85 746 TIGRFAM TIGR04346 DotA_TraY: conjugal transfer/type IV secretion protein DotA/TraY 57 697 2.0E-108 T 28-03-2018 IPR027628 Conjugal transfer/type IV secretion protein DotA/TraY hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 14 277 34.772 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 Gene3D G3DSA:3.10.20.10 40 126 5.9E-23 T 28-03-2018 hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 SUPERFAMILY SSF53927 19 277 1.8E-84 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 Gene3D G3DSA:3.40.140.10 141 277 1.8E-48 T 28-03-2018 hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 Pfam PF02634 FdhD/NarQ family 38 276 6.8E-79 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 35 276 4.7E-70 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 hmeg3_RS16115 7409236af6a2d0f5dcf1b2519196e497 277 PIRSF PIRSF015626 7 277 7.6E-86 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 Gene3D G3DSA:2.40.50.140 1 70 2.6E-25 T 28-03-2018 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 PRINTS PR00050 Cold shock protein signature 6 21 7.8E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 PRINTS PR00050 Cold shock protein signature 27 36 7.8E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 PRINTS PR00050 Cold shock protein signature 42 60 7.8E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 SUPERFAMILY SSF50249 4 69 4.41E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 SMART SM00357 5 69 7.8E-24 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 PIRSF PIRSF002599 1 70 2.0E-20 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 hmeg3_RS01760 44fc6debe4f3ef702766d6e7b09040ef 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 9.3E-26 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS16180 59453418b5463336dc1d3b8eeae3961d 264 Gene3D G3DSA:3.40.1130.10 48 263 9.5E-27 T 28-03-2018 hmeg3_RS16180 59453418b5463336dc1d3b8eeae3961d 264 SMART SM00563 97 205 3.4E-17 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS16180 59453418b5463336dc1d3b8eeae3961d 264 Pfam PF01553 Acyltransferase 85 202 1.4E-14 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS16180 59453418b5463336dc1d3b8eeae3961d 264 SUPERFAMILY SSF69593 62 262 1.09E-27 T 28-03-2018 hmeg3_RS21670 de4d8ad92d8e155857f5b2bc90444432 151 Gene3D G3DSA:3.50.80.10 1 145 6.3E-51 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain hmeg3_RS21670 de4d8ad92d8e155857f5b2bc90444432 151 SUPERFAMILY SSF69500 1 144 1.1E-52 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain hmeg3_RS21670 de4d8ad92d8e155857f5b2bc90444432 151 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 5.7E-51 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 hmeg3_RS21670 de4d8ad92d8e155857f5b2bc90444432 151 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 33.097 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 hmeg3_RS21670 de4d8ad92d8e155857f5b2bc90444432 151 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 4.3E-54 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 Gene3D G3DSA:3.40.50.300 198 712 3.4E-87 T 28-03-2018 hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 Pfam PF13361 UvrD-like helicase C-terminal domain 278 645 2.3E-68 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 272 2.0E-73 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 Gene3D G3DSA:1.10.10.160 127 184 2.4E-17 T 28-03-2018 hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 SUPERFAMILY SSF52540 1 527 2.52E-166 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 SUPERFAMILY SSF52540 573 670 2.52E-166 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21520 b79c497708836815adb083a5e81f7913 765 Gene3D G3DSA:3.40.50.300 1 126 1.3E-27 T 28-03-2018 hmeg3_RS20250 855c88443c2602fdc7fb1cfdcfd5e9f1 217 Pfam PF13417 Glutathione S-transferase, N-terminal domain 11 81 3.0E-8 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS20250 855c88443c2602fdc7fb1cfdcfd5e9f1 217 SUPERFAMILY SSF47616 85 205 3.84E-20 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS20250 855c88443c2602fdc7fb1cfdcfd5e9f1 217 Gene3D G3DSA:1.20.1050.10 95 214 1.2E-20 T 28-03-2018 hmeg3_RS20250 855c88443c2602fdc7fb1cfdcfd5e9f1 217 Gene3D G3DSA:3.40.30.10 3 94 4.6E-16 T 28-03-2018 hmeg3_RS20250 855c88443c2602fdc7fb1cfdcfd5e9f1 217 SUPERFAMILY SSF52833 7 87 6.87E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS02040 6d3dacc0c484e349e4d20f5418254a3f 186 Gene3D G3DSA:3.40.50.360 1 178 2.6E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS02040 6d3dacc0c484e349e4d20f5418254a3f 186 SUPERFAMILY SSF52218 4 179 9.71E-52 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS02040 6d3dacc0c484e349e4d20f5418254a3f 186 Pfam PF02525 Flavodoxin-like fold 5 171 3.2E-43 T 28-03-2018 IPR003680 Flavodoxin-like fold hmeg3_RS12140 57cab2e7678191a8ea474541bddb1a79 175 Gene3D G3DSA:3.90.1720.10 45 174 1.1E-31 T 28-03-2018 hmeg3_RS12140 57cab2e7678191a8ea474541bddb1a79 175 Pfam PF00877 NlpC/P60 family 61 167 1.7E-26 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain hmeg3_RS12140 57cab2e7678191a8ea474541bddb1a79 175 SUPERFAMILY SSF54001 60 169 2.45E-35 T 28-03-2018 hmeg3_RS02960 a4717cbc88d93cbf148bf2422b062c16 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.6E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02960 a4717cbc88d93cbf148bf2422b062c16 233 SMART SM00862 145 223 8.0E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS02960 a4717cbc88d93cbf148bf2422b062c16 233 Gene3D G3DSA:1.10.10.10 110 229 8.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS02960 a4717cbc88d93cbf148bf2422b062c16 233 SUPERFAMILY SSF46894 122 223 7.31E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS07870 113f2b93042919189f1de03cf6dc6fa5 355 Gene3D G3DSA:3.20.20.30 30 353 6.1E-72 T 28-03-2018 hmeg3_RS07870 113f2b93042919189f1de03cf6dc6fa5 355 Pfam PF00296 Luciferase-like monooxygenase 34 323 6.0E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS07870 113f2b93042919189f1de03cf6dc6fa5 355 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 25 350 5.8E-115 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 hmeg3_RS07870 113f2b93042919189f1de03cf6dc6fa5 355 SUPERFAMILY SSF51679 23 350 1.07E-74 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS05900 5cc62b71645bc8dea1de47aabadfeb95 302 SUPERFAMILY SSF52540 78 266 5.32E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05900 5cc62b71645bc8dea1de47aabadfeb95 302 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 47 273 1.4E-114 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 hmeg3_RS05900 5cc62b71645bc8dea1de47aabadfeb95 302 PIRSF PIRSF028756 10 302 1.1E-134 T 28-03-2018 IPR016898 Polyphosphate kinase 2 hmeg3_RS05900 5cc62b71645bc8dea1de47aabadfeb95 302 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 47 273 2.9E-113 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related hmeg3_RS05900 5cc62b71645bc8dea1de47aabadfeb95 302 Gene3D G3DSA:3.40.50.300 3 294 6.3E-116 T 28-03-2018 hmeg3_RS18615 535a508e4dfe25542e20dda1867043c4 151 SMART SM00448 7 131 1.8E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18615 535a508e4dfe25542e20dda1867043c4 151 Pfam PF00072 Response regulator receiver domain 9 131 3.8E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18615 535a508e4dfe25542e20dda1867043c4 151 SUPERFAMILY SSF52172 7 134 6.69E-28 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS18615 535a508e4dfe25542e20dda1867043c4 151 Gene3D G3DSA:3.40.50.2300 1 135 8.8E-28 T 28-03-2018 hmeg3_RS05020 443bbfc0a45ce10254ab97060122ede9 624 Pfam PF13687 Domain of unknown function (DUF4153) 183 420 2.8E-18 T 28-03-2018 IPR025291 Protein of unknown function DUF4153 hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 SUPERFAMILY SSF54593 17 351 6.94E-82 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 25 363 1.6E-125 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 Gene3D G3DSA:3.10.180.10 14 166 8.3E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 17 155 1.5E-62 T 28-03-2018 hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 PIRSF PIRSF009283 9 364 1.8E-117 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 Gene3D G3DSA:3.10.180.10 169 363 7.3E-58 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS14230 84b3b3e2e27afd4a5e559c27ea6f582c 364 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 172 283 2.9E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS05620 f8921944a5692b670e17d54b5cdcac96 161 Gene3D G3DSA:3.40.50.960 6 152 4.1E-54 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05620 f8921944a5692b670e17d54b5cdcac96 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 147 2.1E-49 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05620 f8921944a5692b670e17d54b5cdcac96 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 27.397 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05620 f8921944a5692b670e17d54b5cdcac96 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 147 1.3E-39 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS05620 f8921944a5692b670e17d54b5cdcac96 161 SUPERFAMILY SSF52121 5 151 1.31E-53 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 hmeg3_RS20180 1e524d0c84a56d015eb15871a7a2bae3 325 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 315 1.2E-59 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 hmeg3_RS20180 1e524d0c84a56d015eb15871a7a2bae3 325 SMART SM00062 34 256 2.7E-16 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS20180 1e524d0c84a56d015eb15871a7a2bae3 325 Pfam PF09084 NMT1/THI5 like 80 256 2.3E-14 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS20180 1e524d0c84a56d015eb15871a7a2bae3 325 SUPERFAMILY SSF53850 33 270 3.82E-48 T 28-03-2018 hmeg3_RS20180 1e524d0c84a56d015eb15871a7a2bae3 325 Gene3D G3DSA:3.40.190.10 141 317 1.9E-33 T 28-03-2018 hmeg3_RS20180 1e524d0c84a56d015eb15871a7a2bae3 325 Gene3D G3DSA:3.40.190.10 29 140 4.6E-11 T 28-03-2018 hmeg3_RS11385 c05f2663fc753fafd96ee5814172ab7f 239 SUPERFAMILY SSF58104 68 198 5.89E-24 T 28-03-2018 hmeg3_RS11385 c05f2663fc753fafd96ee5814172ab7f 239 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 144 171 1.9E-13 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11385 c05f2663fc753fafd96ee5814172ab7f 239 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 63 92 1.9E-13 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11385 c05f2663fc753fafd96ee5814172ab7f 239 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 173 202 1.9E-13 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS11385 c05f2663fc753fafd96ee5814172ab7f 239 Gene3D G3DSA:1.10.287.950 46 239 3.8E-22 T 28-03-2018 hmeg3_RS11385 c05f2663fc753fafd96ee5814172ab7f 239 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 148 193 1.1E-16 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 SUPERFAMILY SSF54106 405 448 2.88E-7 T 28-03-2018 IPR018392 LysM domain hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 Gene3D G3DSA:3.10.350.10 400 466 9.2E-10 T 28-03-2018 hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 Gene3D G3DSA:3.10.350.10 323 386 2.5E-5 T 28-03-2018 hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 116 144 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 SUPERFAMILY SSF53955 54 237 1.69E-40 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 Pfam PF01476 LysM domain 338 372 5.4E-4 T 28-03-2018 IPR018392 LysM domain hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 Pfam PF01476 LysM domain 410 446 9.5E-7 T 28-03-2018 IPR018392 LysM domain hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 Gene3D G3DSA:1.10.530.10 69 241 2.1E-33 T 28-03-2018 hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 SMART SM00257 405 448 3.7E-4 T 28-03-2018 IPR018392 LysM domain hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 SMART SM00257 327 372 3.6 T 28-03-2018 IPR018392 LysM domain hmeg3_RS07040 eb36e9d6b02084ef7b0d71f9f6c5fcf3 512 Pfam PF01464 Transglycosylase SLT domain 105 203 1.7E-24 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 hmeg3_RS05750 10a674c800c501bcb9e071a880ba9823 323 PIRSF PIRSF036979 10 314 6.8E-50 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS05750 10a674c800c501bcb9e071a880ba9823 323 Gene3D G3DSA:3.40.800.10 5 323 6.6E-68 T 28-03-2018 hmeg3_RS05750 10a674c800c501bcb9e071a880ba9823 323 Pfam PF00491 Arginase family 29 308 6.3E-57 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 hmeg3_RS05750 10a674c800c501bcb9e071a880ba9823 323 SUPERFAMILY SSF52768 8 311 2.16E-63 T 28-03-2018 hmeg3_RS13650 9a3f15df4b4e25271886aa220b0d246a 206 Pfam PF01810 LysE type translocator 16 202 1.1E-37 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS06290 d9ea124358a7454a9b0e0bab06cba2f9 241 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 217 6.8E-27 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 Gene3D G3DSA:2.40.110.10 124 220 1.0E-29 T 28-03-2018 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 SUPERFAMILY SSF56645 4 231 2.62E-63 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 379 5.0E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 SUPERFAMILY SSF47203 230 382 4.51E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 Gene3D G3DSA:1.10.540.10 2 122 3.4E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 PIRSF PIRSF016578 7 378 2.5E-25 T 28-03-2018 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 119 9.8E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 Gene3D G3DSA:1.20.140.10 221 389 9.6E-47 T 28-03-2018 hmeg3_RS20945 427adea30f0c44258a23ad72671eee1f 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 2.1E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS00600 cd59910baba4c209716148a3f417e9de 203 Gene3D G3DSA:3.40.30.10 2 201 4.0E-51 T 28-03-2018 hmeg3_RS00600 cd59910baba4c209716148a3f417e9de 203 SUPERFAMILY SSF52833 8 200 6.92E-45 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS00600 cd59910baba4c209716148a3f417e9de 203 Pfam PF01323 DSBA-like thioredoxin domain 8 198 1.0E-40 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 hmeg3_RS00600 cd59910baba4c209716148a3f417e9de 203 PIRSF PIRSF006386 2 203 8.0E-55 T 28-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 hmeg3_RS09890 f4e7b7856006a04b53d06e4613762638 295 Pfam PF00483 Nucleotidyl transferase 12 269 1.7E-25 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS09890 f4e7b7856006a04b53d06e4613762638 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 269 2.9E-111 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 hmeg3_RS09890 f4e7b7856006a04b53d06e4613762638 295 Gene3D G3DSA:3.90.550.10 1 282 4.5E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS09890 f4e7b7856006a04b53d06e4613762638 295 SUPERFAMILY SSF53448 2 273 5.63E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS04845 c1186ccf79bc37cc9db328f2213de442 353 SUPERFAMILY SSF56176 14 171 1.87E-32 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS04845 c1186ccf79bc37cc9db328f2213de442 353 SUPERFAMILY SSF55103 134 349 1.96E-20 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS04845 c1186ccf79bc37cc9db328f2213de442 353 Gene3D G3DSA:1.10.45.10 317 350 5.9E-7 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 hmeg3_RS04845 c1186ccf79bc37cc9db328f2213de442 353 Pfam PF01565 FAD binding domain 13 133 1.5E-21 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS04845 c1186ccf79bc37cc9db328f2213de442 353 Gene3D G3DSA:3.30.465.10 48 170 6.5E-27 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS15690 20fed350abc3050eb370d141a13d7765 127 Gene3D G3DSA:1.10.1220.10 85 127 4.3E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 hmeg3_RS15690 20fed350abc3050eb370d141a13d7765 127 SUPERFAMILY SSF47598 88 121 2.45E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 hmeg3_RS15690 20fed350abc3050eb370d141a13d7765 127 Gene3D G3DSA:3.30.2390.10 3 67 5.5E-10 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like hmeg3_RS15690 20fed350abc3050eb370d141a13d7765 127 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 121 9.6E-37 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system hmeg3_RS15690 20fed350abc3050eb370d141a13d7765 127 SUPERFAMILY SSF143100 1 60 8.63E-12 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 Gene3D G3DSA:1.10.287.950 330 524 2.8E-45 T 28-03-2018 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 Gene3D G3DSA:1.10.287.950 33 329 9.2E-18 T 28-03-2018 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 Pfam PF00672 HAMP domain 222 269 7.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 372 399 6.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 449 478 6.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 430 6.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 198 218 6.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 295 324 6.6E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 SMART SM00283 274 521 2.7E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 SUPERFAMILY SSF58104 241 522 6.02E-73 T 28-03-2018 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 488 1.6E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20865 f01f2b0fa4af6d05369aa514ac720a83 524 SMART SM00304 221 273 1.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 Gene3D G3DSA:3.30.300.30 438 548 3.4E-31 T 28-03-2018 hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 529 2.5E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 SUPERFAMILY SSF56801 7 540 6.93E-143 T 28-03-2018 hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 28-03-2018 IPR020845 AMP-binding, conserved site hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 Pfam PF00501 AMP-binding enzyme 32 441 5.6E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 Gene3D G3DSA:3.40.50.980 197 348 1.9E-34 T 28-03-2018 hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 Gene3D G3DSA:3.40.50.980 24 196 6.5E-40 T 28-03-2018 hmeg3_RS05060 566affb161827fbcf5c009f5b8746d32 549 Gene3D G3DSA:2.30.38.10 349 435 2.9E-21 T 28-03-2018 hmeg3_RS03775 acf37e6455956f945b81fd453b3a1c7c 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 56 2.0E-5 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS03775 acf37e6455956f945b81fd453b3a1c7c 291 SUPERFAMILY SSF161098 86 273 9.03E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03775 acf37e6455956f945b81fd453b3a1c7c 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 282 9.3E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03775 acf37e6455956f945b81fd453b3a1c7c 291 Gene3D G3DSA:1.10.3720.10 20 282 4.6E-33 T 28-03-2018 hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 TIGRFAM TIGR02693 arsenite_ox_L: arsenite oxidase, large subunit 7 806 0.0 T 28-03-2018 IPR014066 Arsenite oxidase, large subunit MetaCyc: PWY-7429 hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 Pfam PF00384 Molybdopterin oxidoreductase 120 571 5.8E-28 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 SUPERFAMILY SSF53706 7 679 9.91E-146 T 28-03-2018 hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 Gene3D G3DSA:2.40.40.20 682 816 2.4E-24 T 28-03-2018 hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 Gene3D G3DSA:3.40.228.10 200 512 9.7E-58 T 28-03-2018 hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 SUPERFAMILY SSF50692 663 806 8.59E-30 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain hmeg3_RS02275 2c2942a088ade297837c97dadd769cbd 826 Pfam PF01568 Molydopterin dinucleotide binding domain 695 787 1.3E-14 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 298 320 6.9E-23 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 433 446 6.9E-23 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 71 90 6.9E-23 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 371 385 6.9E-23 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 356 370 6.9E-23 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 Gene3D G3DSA:3.40.710.10 27 477 4.2E-43 T 28-03-2018 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 35 472 1.9E-92 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 61 455 1.0E-67 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 hmeg3_RS07160 82ff75909dc60c83f81ad4b2cc1191ca 477 SUPERFAMILY SSF56601 31 475 1.83E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS05110 1ace466426616621babd6819cf661250 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 17 196 0.01 T 28-03-2018 hmeg3_RS05110 1ace466426616621babd6819cf661250 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS05110 1ace466426616621babd6819cf661250 261 Pfam PF00106 short chain dehydrogenase 17 210 6.1E-58 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 Gene3D G3DSA:3.40.50.720 8 258 2.1E-71 T 28-03-2018 hmeg3_RS05110 1ace466426616621babd6819cf661250 261 SUPERFAMILY SSF51735 12 259 1.64E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 6.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 6.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 6.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 6.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 6.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 6.2E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 5.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 5.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05110 1ace466426616621babd6819cf661250 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 5.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01735 81339adc26815d9bfc79551644136bc6 295 Pfam PF05368 NmrA-like family 3 221 3.7E-30 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 hmeg3_RS01735 81339adc26815d9bfc79551644136bc6 295 SUPERFAMILY SSF51735 3 259 3.54E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01735 81339adc26815d9bfc79551644136bc6 295 Gene3D G3DSA:3.40.50.720 1 285 3.9E-26 T 28-03-2018 hmeg3_RS15030 0a5cf8725d7fd9d06d962c10c8480664 380 PIRSF PIRSF000267 3 379 9.3E-123 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 hmeg3_RS15030 0a5cf8725d7fd9d06d962c10c8480664 380 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 363 4.4E-107 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 hmeg3_RS15030 0a5cf8725d7fd9d06d962c10c8480664 380 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 380 2.7E-147 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 hmeg3_RS09775 ca42f8dda8050317bf86e641d97d8536 144 SUPERFAMILY SSF55729 4 144 1.37E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS09775 ca42f8dda8050317bf86e641d97d8536 144 Pfam PF00583 Acetyltransferase (GNAT) family 10 117 8.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS09775 ca42f8dda8050317bf86e641d97d8536 144 Gene3D G3DSA:3.40.630.30 2 144 7.8E-27 T 28-03-2018 hmeg3_RS09775 ca42f8dda8050317bf86e641d97d8536 144 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 7 140 2.8E-35 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 hmeg3_RS00585 4da6f65bfbe75800cbeae4df9a1a058f 386 SUPERFAMILY SSF53474 25 275 1.54E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00585 4da6f65bfbe75800cbeae4df9a1a058f 386 Gene3D G3DSA:3.40.50.1820 22 275 1.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00585 4da6f65bfbe75800cbeae4df9a1a058f 386 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 47 179 1.3E-10 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 hmeg3_RS12950 45f1c0d5f7b977864c260a9941f32cc2 629 SUPERFAMILY SSF56349 245 539 2.15E-22 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS12950 45f1c0d5f7b977864c260a9941f32cc2 629 Gene3D G3DSA:1.10.150.130 237 348 1.4E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS12950 45f1c0d5f7b977864c260a9941f32cc2 629 ProSitePatterns PS00208 Plant hemoglobins signature. 102 113 - T 28-03-2018 IPR019824 Leghaemoglobin, iron-binding site GO:0019825|GO:0020037 hmeg3_RS12950 45f1c0d5f7b977864c260a9941f32cc2 629 Gene3D G3DSA:1.10.443.10 380 544 2.3E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 Gene3D G3DSA:3.40.50.1860 368 479 1.9E-23 T 28-03-2018 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 SUPERFAMILY SSF53681 250 360 2.88E-28 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 326 334 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 SUPERFAMILY SSF53681 12 122 1.8E-13 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 Gene3D G3DSA:3.40.50.1860 125 228 2.2E-11 T 28-03-2018 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 450 460 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 Gene3D G3DSA:3.40.50.1860 247 367 1.5E-36 T 28-03-2018 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 Gene3D G3DSA:3.40.50.1860 8 124 4.0E-17 T 28-03-2018 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 SUPERFAMILY SSF53681 128 240 1.83E-14 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 Pfam PF01177 Asp/Glu/Hydantoin racemase 15 237 7.5E-27 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 Pfam PF01177 Asp/Glu/Hydantoin racemase 254 488 3.4E-59 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 TIGRFAM TIGR00035 asp_race: aspartate racemase 251 491 1.9E-50 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 hmeg3_RS24405 08d7bfdc1e50cff59a6af1d1a9186be5 499 SUPERFAMILY SSF53681 367 491 1.08E-22 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 Gene3D G3DSA:3.40.50.720 1 256 7.4E-53 T 28-03-2018 hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 Pfam PF00106 short chain dehydrogenase 3 192 5.7E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 SUPERFAMILY SSF51735 3 248 1.41E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.8E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02510 5d9407d5b32667c16fc476fe2c816e27 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20290 2cd7b4b1a3b055f5cce0a37f0cf0a6b1 224 Gene3D G3DSA:3.40.50.1000 77 212 5.3E-12 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS20290 2cd7b4b1a3b055f5cce0a37f0cf0a6b1 224 Gene3D G3DSA:1.20.1440.100 16 76 3.5E-27 T 28-03-2018 hmeg3_RS20290 2cd7b4b1a3b055f5cce0a37f0cf0a6b1 224 SUPERFAMILY SSF56784 2 211 5.11E-31 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS20290 2cd7b4b1a3b055f5cce0a37f0cf0a6b1 224 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 205 1.9E-37 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like hmeg3_RS20290 2cd7b4b1a3b055f5cce0a37f0cf0a6b1 224 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 194 3.3E-20 T 28-03-2018 hmeg3_RS20290 2cd7b4b1a3b055f5cce0a37f0cf0a6b1 224 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 191 5.8E-37 T 28-03-2018 hmeg3_RS19810 0c328c1c84468d543bf76c1095b63702 361 Gene3D G3DSA:3.40.50.300 120 327 3.7E-30 T 28-03-2018 hmeg3_RS19810 0c328c1c84468d543bf76c1095b63702 361 SUPERFAMILY SSF52540 94 302 9.18E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19810 0c328c1c84468d543bf76c1095b63702 361 Pfam PF02562 PhoH-like protein 125 327 4.8E-94 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 hmeg3_RS18720 9f3a10c3e7ce14362a65d48e4eace0fb 141 SUPERFAMILY SSF55961 11 138 1.13E-26 T 28-03-2018 hmeg3_RS18720 9f3a10c3e7ce14362a65d48e4eace0fb 141 Gene3D G3DSA:3.30.530.20 2 139 4.9E-19 T 28-03-2018 IPR023393 START-like domain hmeg3_RS18720 9f3a10c3e7ce14362a65d48e4eace0fb 141 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 138 2.9E-11 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase hmeg3_RS15145 88a0ac4f664c0df7cd683355f8e3ea89 193 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 187 5.6E-64 T 28-03-2018 IPR006286 Peptidase C56, PfpI hmeg3_RS15145 88a0ac4f664c0df7cd683355f8e3ea89 193 Gene3D G3DSA:3.40.50.880 1 192 5.4E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS15145 88a0ac4f664c0df7cd683355f8e3ea89 193 SUPERFAMILY SSF52317 4 188 4.16E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS15145 88a0ac4f664c0df7cd683355f8e3ea89 193 Pfam PF01965 DJ-1/PfpI family 4 185 3.9E-54 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS10920 1cee6535751e18ea0c6e443d7c0eb63d 295 SUPERFAMILY SSF53639 57 264 4.91E-52 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS10920 1cee6535751e18ea0c6e443d7c0eb63d 295 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 64 245 1.4E-39 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS10920 1cee6535751e18ea0c6e443d7c0eb63d 295 SMART SM01007 63 245 4.3E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS10920 1cee6535751e18ea0c6e443d7c0eb63d 295 Gene3D G3DSA:3.40.225.10 54 289 4.2E-56 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS09435 fa99b0b6ad80c46e73768402641c7762 220 SUPERFAMILY SSF161098 10 208 2.75E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09435 fa99b0b6ad80c46e73768402641c7762 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 219 8.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09435 fa99b0b6ad80c46e73768402641c7762 220 Gene3D G3DSA:1.10.3720.10 8 220 6.8E-31 T 28-03-2018 hmeg3_RS16880 01bdff5c55a080ec93767be84e3117ac 385 Gene3D G3DSA:3.40.630.30 193 344 1.9E-34 T 28-03-2018 hmeg3_RS16880 01bdff5c55a080ec93767be84e3117ac 385 SUPERFAMILY SSF55729 182 350 2.75E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS16880 01bdff5c55a080ec93767be84e3117ac 385 Gene3D G3DSA:3.40.630.30 14 192 1.2E-18 T 28-03-2018 hmeg3_RS16880 01bdff5c55a080ec93767be84e3117ac 385 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 15 380 9.0E-153 T 28-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition hmeg3_RS00325 68359c697395411fc612bed417fc632c 538 SUPERFAMILY SSF48371 30 60 3.33E-5 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 hmeg3_RS00325 68359c697395411fc612bed417fc632c 538 SUPERFAMILY SSF48371 108 237 3.33E-5 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 hmeg3_RS00325 68359c697395411fc612bed417fc632c 538 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 244 535 8.4E-131 T 28-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type hmeg3_RS00325 68359c697395411fc612bed417fc632c 538 Pfam PF02653 Branched-chain amino acid transport system / permease component 246 521 1.6E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00325 68359c697395411fc612bed417fc632c 538 Gene3D G3DSA:1.10.3470.10 185 526 1.2E-48 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS22435 f0573feff069428141c19437e3b633ab 248 ProSitePatterns PS01228 Hypothetical cof family signature 1. 14 25 - T 28-03-2018 hmeg3_RS22435 f0573feff069428141c19437e3b633ab 248 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 15 207 8.0E-15 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 hmeg3_RS22435 f0573feff069428141c19437e3b633ab 248 SUPERFAMILY SSF56784 14 240 1.27E-39 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS22435 f0573feff069428141c19437e3b633ab 248 Pfam PF02358 Trehalose-phosphatase 16 227 4.6E-38 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 hmeg3_RS22435 f0573feff069428141c19437e3b633ab 248 Gene3D G3DSA:3.40.50.1000 14 248 4.2E-25 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS22435 f0573feff069428141c19437e3b633ab 248 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 13 239 2.7E-43 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 hmeg3_RS12635 3b0c694615c767f99405eb29d4db3e12 344 Pfam PF02625 XdhC and CoxI family 15 69 5.5E-21 T 28-03-2018 IPR003777 XdhC- CoxI hmeg3_RS12635 3b0c694615c767f99405eb29d4db3e12 344 Gene3D G3DSA:3.40.50.720 162 322 4.6E-6 T 28-03-2018 hmeg3_RS12635 3b0c694615c767f99405eb29d4db3e12 344 SUPERFAMILY SSF51735 164 275 7.42E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12635 3b0c694615c767f99405eb29d4db3e12 344 Pfam PF13478 XdhC Rossmann domain 165 306 6.1E-35 T 28-03-2018 IPR027051 XdhC Rossmann domain hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 Pfam PF01195 Peptidyl-tRNA hydrolase 5 187 2.7E-60 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 182 36.297 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 108 118 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 4 189 8.2E-62 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 Gene3D G3DSA:3.40.50.1470 1 193 4.3E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 hmeg3_RS03150 d0c3ea48916d3c751607dcea0bcb6ca5 193 SUPERFAMILY SSF53178 3 189 5.75E-66 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 SUPERFAMILY SSF51726 411 771 3.4E-117 T 28-03-2018 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 Gene3D G3DSA:3.20.20.210 405 772 3.1E-124 T 28-03-2018 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 329 9.2E-108 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 Gene3D G3DSA:3.20.20.210 11 404 4.4E-134 T 28-03-2018 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 PIRSF PIRSF000382 10 772 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 SUPERFAMILY SSF51726 13 409 2.22E-103 T 28-03-2018 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 772 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 446 768 6.1E-148 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS13365 96c6aae45d33ed88e89151c087db80b8 772 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 11 772 35.568 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 SUPERFAMILY SSF81296 291 407 4.97E-30 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 289 399 3.8E-16 T 28-03-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 Pfam PF00174 Oxidoreductase molybdopterin binding domain 105 265 4.2E-51 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 11 415 2.0E-196 T 28-03-2018 IPR030835 Sulfite dehydrogenase SoxC hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 SUPERFAMILY SSF56524 56 295 1.7E-72 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 Gene3D G3DSA:3.90.420.10 33 289 8.7E-64 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 216 232 3.5E-20 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 145 156 3.5E-20 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 93 109 3.5E-20 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 327 339 3.5E-20 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 249 262 3.5E-20 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 PRINTS PR00407 Eukaryotic molybdopterin domain signature 233 246 3.5E-20 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 hmeg3_RS11220 99b1423224beead2882616d470431fb5 417 Gene3D G3DSA:2.60.40.650 290 417 3.3E-29 T 28-03-2018 hmeg3_RS15755 aabf5b9172c1679ae14fc2b78964d404 102 SUPERFAMILY SSF47336 23 95 1.11E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS15755 aabf5b9172c1679ae14fc2b78964d404 102 ProSitePatterns PS00012 Phosphopantetheine attachment site. 50 65 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS15755 aabf5b9172c1679ae14fc2b78964d404 102 Pfam PF00550 Phosphopantetheine attachment site 49 89 8.1E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS15755 aabf5b9172c1679ae14fc2b78964d404 102 Gene3D G3DSA:1.10.1200.10 20 95 1.6E-10 T 28-03-2018 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 PRINTS PR00395 Ribosomal protein S2 signature 195 209 7.8E-34 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 PRINTS PR00395 Ribosomal protein S2 signature 36 45 7.8E-34 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 PRINTS PR00395 Ribosomal protein S2 signature 5 23 7.8E-34 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 PRINTS PR00395 Ribosomal protein S2 signature 157 174 7.8E-34 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 PRINTS PR00395 Ribosomal protein S2 signature 174 185 7.8E-34 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 PRINTS PR00395 Ribosomal protein S2 signature 86 103 7.8E-34 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 Pfam PF00318 Ribosomal protein S2 8 223 2.0E-89 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 Gene3D G3DSA:3.40.50.10490 4 249 5.1E-88 T 28-03-2018 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 1.3E-96 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 SUPERFAMILY SSF52313 5 231 1.57E-89 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 5 16 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 hmeg3_RS09935 36eeec62d36e976cf0d12edf33487d39 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 224 39.343 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS12335 6fbaf58d87d611b0f5c32fe9b845b05e 372 Gene3D G3DSA:3.40.50.1970 1 183 2.6E-36 T 28-03-2018 hmeg3_RS12335 6fbaf58d87d611b0f5c32fe9b845b05e 372 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 350 1.2E-79 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 hmeg3_RS12335 6fbaf58d87d611b0f5c32fe9b845b05e 372 TIGRFAM TIGR03405 Phn_Fe-ADH: phosphonate metabolism-associated iron-containing alcohol dehydrogenase 4 358 4.2E-141 T 28-03-2018 IPR017775 Alcohol dehydrogenase, iron-type, phosphonate metabolism-associated hmeg3_RS12335 6fbaf58d87d611b0f5c32fe9b845b05e 372 SUPERFAMILY SSF56796 2 351 4.71E-81 T 28-03-2018 hmeg3_RS12335 6fbaf58d87d611b0f5c32fe9b845b05e 372 Gene3D G3DSA:1.20.1090.10 184 369 1.3E-40 T 28-03-2018 hmeg3_RS12335 6fbaf58d87d611b0f5c32fe9b845b05e 372 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 SUPERFAMILY SSF46785 40 157 2.17E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 Gene3D G3DSA:1.10.10.10 2 160 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 Pfam PF01047 MarR family 52 104 1.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 5.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 5.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 5.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 5.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS23995 5dced4d096fefdf50ca3c467e89b9129 160 SMART SM00347 40 140 3.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 Gene3D G3DSA:3.90.1150.10 318 433 1.3E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 21 431 3.9E-191 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 SUPERFAMILY SSF53383 35 431 1.14E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 PIRSF PIRSF000521 133 434 1.3E-41 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 PIRSF PIRSF000521 2 141 2.9E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 Pfam PF00202 Aminotransferase class-III 36 431 1.7E-127 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 Gene3D G3DSA:3.40.640.10 197 317 4.1E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 Gene3D G3DSA:3.90.1150.10 5 196 8.5E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS12005 9057b6e08a400b49678875003a014320 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 284 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 hmeg3_RS19190 a57540ccd729739171b9edd307e48da6 278 Pfam PF00005 ABC transporter 42 199 1.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19190 a57540ccd729739171b9edd307e48da6 278 Gene3D G3DSA:3.40.50.300 18 275 8.8E-51 T 28-03-2018 hmeg3_RS19190 a57540ccd729739171b9edd307e48da6 278 SMART SM00382 48 247 6.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19190 a57540ccd729739171b9edd307e48da6 278 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 248 270 1.6E-12 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS19190 a57540ccd729739171b9edd307e48da6 278 SUPERFAMILY SSF52540 21 271 5.87E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12925 a498d08056b0c9904c09c39b24aeca0a 116 Pfam PF12681 Glyoxalase-like domain 12 112 1.2E-10 T 28-03-2018 IPR025870 Glyoxalase-like domain hmeg3_RS12925 a498d08056b0c9904c09c39b24aeca0a 116 SUPERFAMILY SSF54593 7 112 1.34E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS12925 a498d08056b0c9904c09c39b24aeca0a 116 Gene3D G3DSA:3.10.180.10 6 116 7.3E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS18755 e78fee44e679410af374036e7464f458 414 Pfam PF11871 Domain of unknown function (DUF3391) 4 126 1.6E-29 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 hmeg3_RS18755 e78fee44e679410af374036e7464f458 414 SUPERFAMILY SSF109604 149 314 5.76E-31 T 28-03-2018 hmeg3_RS18755 e78fee44e679410af374036e7464f458 414 Pfam PF01966 HD domain 159 280 2.9E-13 T 28-03-2018 IPR006674 HD domain hmeg3_RS18755 e78fee44e679410af374036e7464f458 414 Gene3D G3DSA:1.10.3210.10 85 320 2.4E-41 T 28-03-2018 hmeg3_RS18755 e78fee44e679410af374036e7464f458 414 SMART SM00471 154 290 7.7E-11 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS08330 9a194e98b013deca9befeee7c77b3746 252 Gene3D G3DSA:2.40.10.220 121 251 1.1E-16 T 28-03-2018 hmeg3_RS08330 9a194e98b013deca9befeee7c77b3746 252 Gene3D G3DSA:2.30.110.10 15 120 5.7E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS08330 9a194e98b013deca9befeee7c77b3746 252 Pfam PF07238 PilZ domain 122 238 6.2E-10 T 28-03-2018 IPR009875 PilZ domain GO:0035438 hmeg3_RS08330 9a194e98b013deca9befeee7c77b3746 252 Pfam PF07317 Flagellar regulator YcgR 14 120 3.0E-27 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal hmeg3_RS08330 9a194e98b013deca9befeee7c77b3746 252 Hamap MF_01457 Flagellar brake protein YcgR [ycgR]. 9 248 28.967 T 28-03-2018 IPR023787 Type III secretion system flagellar brake protein YcgR GO:0035438|GO:0071945 hmeg3_RS07350 c2534579d4749eb8e8e6a99c11e6e3c8 302 Gene3D G3DSA:1.10.287.540 226 299 7.1E-6 T 28-03-2018 hmeg3_RS07350 c2534579d4749eb8e8e6a99c11e6e3c8 302 SUPERFAMILY SSF109709 144 210 3.92E-7 T 28-03-2018 hmeg3_RS07350 c2534579d4749eb8e8e6a99c11e6e3c8 302 Gene3D G3DSA:1.10.10.10 11 225 0.038 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS17445 f621255bf08a5cf96b0bcafac2d8e4f0 336 Pfam PF13379 NMT1-like family 28 253 1.4E-24 T 28-03-2018 hmeg3_RS17445 f621255bf08a5cf96b0bcafac2d8e4f0 336 SUPERFAMILY SSF53850 30 252 5.56E-38 T 28-03-2018 hmeg3_RS17445 f621255bf08a5cf96b0bcafac2d8e4f0 336 Gene3D G3DSA:3.40.190.10 25 131 1.7E-15 T 28-03-2018 hmeg3_RS17445 f621255bf08a5cf96b0bcafac2d8e4f0 336 Gene3D G3DSA:3.40.190.10 132 335 4.1E-26 T 28-03-2018 hmeg3_RS03350 1b7431ebdf007ccbc0b5efa80a89cb00 230 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03350 1b7431ebdf007ccbc0b5efa80a89cb00 230 SUPERFAMILY SSF52540 1 217 1.3E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03350 1b7431ebdf007ccbc0b5efa80a89cb00 230 Pfam PF00005 ABC transporter 18 166 6.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03350 1b7431ebdf007ccbc0b5efa80a89cb00 230 Gene3D G3DSA:3.40.50.300 1 219 3.5E-63 T 28-03-2018 hmeg3_RS03350 1b7431ebdf007ccbc0b5efa80a89cb00 230 SMART SM00382 27 213 9.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15195 15c69c5b3febd64f1a4c5af90941ac42 348 Pfam PF04545 Sigma-70, region 4 18 50 1.8E-6 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS15195 15c69c5b3febd64f1a4c5af90941ac42 348 SUPERFAMILY SSF100950 66 319 5.44E-64 T 28-03-2018 hmeg3_RS15195 15c69c5b3febd64f1a4c5af90941ac42 348 SUPERFAMILY SSF88659 16 50 2.62E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS15195 15c69c5b3febd64f1a4c5af90941ac42 348 Gene3D G3DSA:3.40.50.1360 57 324 3.5E-39 T 28-03-2018 hmeg3_RS15195 15c69c5b3febd64f1a4c5af90941ac42 348 Gene3D G3DSA:1.10.10.60 1 56 4.8E-15 T 28-03-2018 hmeg3_RS15195 15c69c5b3febd64f1a4c5af90941ac42 348 Pfam PF04198 Putative sugar-binding domain 63 317 1.7E-63 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 hmeg3_RS19220 afa88cca13d336e0adce992edf59dbf8 651 Pfam PF02653 Branched-chain amino acid transport system / permease component 349 606 2.0E-35 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19220 afa88cca13d336e0adce992edf59dbf8 651 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 291 9.1E-34 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19220 afa88cca13d336e0adce992edf59dbf8 651 Gene3D G3DSA:1.10.3470.10 1 296 4.1E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS19220 afa88cca13d336e0adce992edf59dbf8 651 Gene3D G3DSA:1.10.3470.10 335 612 1.4E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS05035 8810ccfeb78e6442a9d611ce5cb02939 375 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 2 370 55.385 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 hmeg3_RS05035 8810ccfeb78e6442a9d611ce5cb02939 375 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 4 369 1.3E-166 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 hmeg3_RS05035 8810ccfeb78e6442a9d611ce5cb02939 375 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 369 2.2E-159 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 hmeg3_RS05035 8810ccfeb78e6442a9d611ce5cb02939 375 Gene3D G3DSA:3.20.20.105 1 374 1.3E-156 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 hmeg3_RS05035 8810ccfeb78e6442a9d611ce5cb02939 375 SUPERFAMILY SSF51713 1 368 2.09E-156 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 hmeg3_RS05035 8810ccfeb78e6442a9d611ce5cb02939 375 Pfam PF01702 Queuine tRNA-ribosyltransferase 128 367 2.7E-91 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 SUPERFAMILY SSF47729 1 90 4.56E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 SMART SM00411 1 90 2.1E-36 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 Gene3D G3DSA:4.10.520.10 1 90 8.7E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 8.4E-33 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.3E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.3E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS10465 6adf26a81280a17309fb8463b2478950 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 6.3E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS01935 698d8daafb8ff9634ff28929578f8111 172 Gene3D G3DSA:3.40.50.150 13 168 8.9E-16 T 28-03-2018 hmeg3_RS01935 698d8daafb8ff9634ff28929578f8111 172 Pfam PF08241 Methyltransferase domain 30 83 7.9E-10 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS01935 698d8daafb8ff9634ff28929578f8111 172 SUPERFAMILY SSF53335 32 157 5.0E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.6E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 244 4.4E-32 T 28-03-2018 hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 SUPERFAMILY SSF51735 9 245 8.96E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02005 e1329f7c74e90c5cb50be2b377e326f8 257 Gene3D G3DSA:3.40.50.720 1 252 6.3E-48 T 28-03-2018 hmeg3_RS04770 6b05596e57a1eb7b350b413c18b0eddf 737 SMART SM00283 472 733 7.4E-72 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04770 6b05596e57a1eb7b350b413c18b0eddf 737 Gene3D G3DSA:1.10.287.950 509 737 5.0E-46 T 28-03-2018 hmeg3_RS04770 6b05596e57a1eb7b350b413c18b0eddf 737 Gene3D G3DSA:1.10.287.950 11 508 0.0067 T 28-03-2018 hmeg3_RS04770 6b05596e57a1eb7b350b413c18b0eddf 737 SUPERFAMILY SSF58104 432 734 1.23E-61 T 28-03-2018 hmeg3_RS04770 6b05596e57a1eb7b350b413c18b0eddf 737 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 516 697 5.1E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS15995 29e4f0dcceb6435b29bb2c398f84e8ec 187 Pfam PF13436 Glycine-zipper domain 72 115 3.4E-9 T 28-03-2018 IPR025693 Glycine-zipper-containing OmpA-like membrane domain hmeg3_RS23420 382605fcf63433f964899278c0a5c674 292 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 75 88 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS23420 382605fcf63433f964899278c0a5c674 292 SMART SM00062 51 281 3.4E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23420 382605fcf63433f964899278c0a5c674 292 Gene3D G3DSA:3.40.190.10 46 171 4.6E-30 T 28-03-2018 hmeg3_RS23420 382605fcf63433f964899278c0a5c674 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 277 1.1E-49 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS23420 382605fcf63433f964899278c0a5c674 292 Gene3D G3DSA:3.40.190.10 172 281 6.3E-12 T 28-03-2018 hmeg3_RS23420 382605fcf63433f964899278c0a5c674 292 SUPERFAMILY SSF53850 21 279 7.82E-50 T 28-03-2018 hmeg3_RS18385 21fbacfad361b245744fdd536d189495 267 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 246 3.2E-88 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 hmeg3_RS18385 21fbacfad361b245744fdd536d189495 267 SUPERFAMILY SSF53448 3 251 8.34E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS18385 21fbacfad361b245744fdd536d189495 267 Gene3D G3DSA:3.90.550.10 1 256 1.4E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS18385 21fbacfad361b245744fdd536d189495 267 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 253 40.394 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 hmeg3_RS18385 21fbacfad361b245744fdd536d189495 267 Pfam PF02348 Cytidylyltransferase 5 224 2.6E-52 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 hmeg3_RS22155 7b0d381ada142110478069736e363235 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 299 2.6E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS22155 7b0d381ada142110478069736e363235 397 SUPERFAMILY SSF111369 64 304 9.55E-65 T 28-03-2018 hmeg3_RS22155 7b0d381ada142110478069736e363235 397 Gene3D G3DSA:2.40.50.100 74 148 5.5E-19 T 28-03-2018 hmeg3_RS22155 7b0d381ada142110478069736e363235 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 379 1.6E-84 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS22155 7b0d381ada142110478069736e363235 397 Gene3D G3DSA:2.40.50.100 174 390 3.2E-4 T 28-03-2018 hmeg3_RS14725 37f814221f02f822cf20663ecc650e7a 577 Gene3D G3DSA:1.10.443.10 249 443 4.8E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS14725 37f814221f02f822cf20663ecc650e7a 577 SUPERFAMILY SSF56349 275 427 6.47E-9 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS07735 ef56fbe0d5949a46894af6f4701a9a7a 427 Pfam PF07690 Major Facilitator Superfamily 16 371 2.3E-61 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS07735 ef56fbe0d5949a46894af6f4701a9a7a 427 SUPERFAMILY SSF103473 7 409 3.92E-89 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07735 ef56fbe0d5949a46894af6f4701a9a7a 427 Gene3D G3DSA:1.20.1250.20 220 415 4.6E-30 T 28-03-2018 hmeg3_RS07735 ef56fbe0d5949a46894af6f4701a9a7a 427 Gene3D G3DSA:1.20.1250.20 1 203 3.8E-46 T 28-03-2018 hmeg3_RS00340 e0ae6126aa97caf5a4421427a3bcb85d 218 Gene3D G3DSA:1.10.3210.10 9 215 4.3E-20 T 28-03-2018 hmeg3_RS00340 e0ae6126aa97caf5a4421427a3bcb85d 218 SUPERFAMILY SSF109604 17 214 2.72E-56 T 28-03-2018 hmeg3_RS00340 e0ae6126aa97caf5a4421427a3bcb85d 218 SMART SM00471 23 141 4.1E-8 T 28-03-2018 IPR003607 HD/PDEase domain hmeg3_RS00340 e0ae6126aa97caf5a4421427a3bcb85d 218 Pfam PF01966 HD domain 28 131 3.4E-11 T 28-03-2018 IPR006674 HD domain hmeg3_RS22555 a168f7db664c363a8b10949ab67c4b55 134 SUPERFAMILY SSF109635 2 93 7.32E-27 T 28-03-2018 hmeg3_RS22555 a168f7db664c363a8b10949ab67c4b55 134 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 97 121 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site hmeg3_RS22555 a168f7db664c363a8b10949ab67c4b55 134 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 16 123 7.5E-42 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 hmeg3_RS22555 a168f7db664c363a8b10949ab67c4b55 134 SUPERFAMILY SSF57716 94 132 2.28E-8 T 28-03-2018 hmeg3_RS22555 a168f7db664c363a8b10949ab67c4b55 134 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 92 126 6.7E-11 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 hmeg3_RS22555 a168f7db664c363a8b10949ab67c4b55 134 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 12 133 27.154 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 hmeg3_RS00575 5c88205b18f27272651bfd509b50b3e6 311 Gene3D G3DSA:3.60.15.10 9 262 1.0E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00575 5c88205b18f27272651bfd509b50b3e6 311 SMART SM00849 21 209 9.3E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00575 5c88205b18f27272651bfd509b50b3e6 311 Pfam PF00753 Metallo-beta-lactamase superfamily 17 209 1.9E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00575 5c88205b18f27272651bfd509b50b3e6 311 SUPERFAMILY SSF56281 17 230 8.12E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS06460 88620a4f06021c48edb665bfb0b5e243 227 Pfam PF05401 Nodulation protein S (NodS) 33 175 3.4E-13 T 28-03-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 hmeg3_RS06460 88620a4f06021c48edb665bfb0b5e243 227 SUPERFAMILY SSF53335 24 213 1.25E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS06460 88620a4f06021c48edb665bfb0b5e243 227 Gene3D G3DSA:3.40.50.150 42 215 1.3E-22 T 28-03-2018 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.5E-32 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 Gene3D G3DSA:4.10.910.10 67 85 1.6E-18 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 SUPERFAMILY SSF46946 2 114 5.23E-46 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 8.8E-53 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 Gene3D G3DSA:4.10.910.10 86 121 3.3E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 Gene3D G3DSA:1.10.8.50 1 66 5.1E-22 T 28-03-2018 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 PIRSF PIRSF002134 1 121 1.1E-42 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22745 366df7981743ab54b95896342c7dc53a 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.122 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS01975 c900c60855431f8aefe1b8e18c7d81d0 301 Gene3D G3DSA:3.90.550.10 12 301 7.3E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01975 c900c60855431f8aefe1b8e18c7d81d0 301 Pfam PF00483 Nucleotidyl transferase 12 248 1.6E-70 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS01975 c900c60855431f8aefe1b8e18c7d81d0 301 SUPERFAMILY SSF53448 11 296 1.75E-91 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01975 c900c60855431f8aefe1b8e18c7d81d0 301 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 12 296 1.1E-155 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 347 358 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 338 419 2.1E-31 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 SUPERFAMILY SSF142984 246 329 1.7E-25 T 28-03-2018 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 224 2.1E-44 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 SMART SM00928 334 379 4.0E-25 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 Gene3D G3DSA:3.10.560.10 241 329 1.2E-4 T 28-03-2018 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 SUPERFAMILY SSF140490 331 428 7.59E-38 T 28-03-2018 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 Pfam PF10531 SLBB domain 248 296 2.5E-12 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 SUPERFAMILY SSF142019 20 245 1.57E-82 T 28-03-2018 hmeg3_RS13760 0a7b88833f809483bcffd841385f0ad7 431 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 19 420 3.1E-193 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS19710 80c49128abd41e38e476bff5a9af1b08 334 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 30 313 1.6E-108 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS19710 80c49128abd41e38e476bff5a9af1b08 334 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 30 285 7.1E-102 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS19710 80c49128abd41e38e476bff5a9af1b08 334 Gene3D G3DSA:3.40.190.10 22 296 0.0035 T 28-03-2018 hmeg3_RS19710 80c49128abd41e38e476bff5a9af1b08 334 PIRSF PIRSF006470 1 330 7.3E-137 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 Pfam PF00460 Flagella basal body rod protein 5 35 3.0E-13 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 1.7E-120 T 28-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 145 243 1.5E-30 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 1.9E-48 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 SUPERFAMILY SSF117143 93 222 6.15E-37 T 28-03-2018 hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site hmeg3_RS08215 46a6adbe4efbe70123b35617b870094e 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 1.1E-26 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain hmeg3_RS15935 09733a2ee1a5edd71bc8d8f109946e0a 296 SUPERFAMILY SSF103481 38 142 2.35E-15 T 28-03-2018 hmeg3_RS15935 09733a2ee1a5edd71bc8d8f109946e0a 296 Pfam PF00892 EamA-like transporter family 153 283 7.1E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS15935 09733a2ee1a5edd71bc8d8f109946e0a 296 Pfam PF00892 EamA-like transporter family 10 138 2.1E-25 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS15935 09733a2ee1a5edd71bc8d8f109946e0a 296 SUPERFAMILY SSF103481 188 287 1.24E-13 T 28-03-2018 hmeg3_RS21135 e6bbf14b108bf3d2a35d44e3a17668e3 486 SUPERFAMILY SSF56954 11 474 2.75E-117 T 28-03-2018 hmeg3_RS21135 e6bbf14b108bf3d2a35d44e3a17668e3 486 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 25 472 9.5E-126 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS21135 e6bbf14b108bf3d2a35d44e3a17668e3 486 Pfam PF02321 Outer membrane efflux protein 72 262 4.2E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS21135 e6bbf14b108bf3d2a35d44e3a17668e3 486 Pfam PF02321 Outer membrane efflux protein 291 470 1.8E-36 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS21135 e6bbf14b108bf3d2a35d44e3a17668e3 486 Gene3D G3DSA:1.20.1600.10 29 478 1.3E-105 T 28-03-2018 hmeg3_RS09955 e7190c00acbd13347abcffa715e0f60e 252 SUPERFAMILY SSF64005 14 235 3.14E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 hmeg3_RS09955 e7190c00acbd13347abcffa715e0f60e 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 240 39.817 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 hmeg3_RS09955 e7190c00acbd13347abcffa715e0f60e 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 hmeg3_RS09955 e7190c00acbd13347abcffa715e0f60e 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 239 1.5E-88 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 hmeg3_RS09955 e7190c00acbd13347abcffa715e0f60e 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 239 3.5E-80 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 hmeg3_RS09955 e7190c00acbd13347abcffa715e0f60e 252 Gene3D G3DSA:3.40.1180.10 2 243 2.5E-89 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 Pfam PF12161 HsdM N-terminal domain 5 148 2.5E-23 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 282 294 2.0E-21 T 28-03-2018 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 208 222 2.0E-21 T 28-03-2018 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 185 201 2.0E-21 T 28-03-2018 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 316 340 2.0E-21 T 28-03-2018 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 Pfam PF02384 N-6 DNA Methylase 161 479 8.0E-112 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 SUPERFAMILY SSF53335 83 519 4.73E-135 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 SUPERFAMILY SSF53335 4 42 4.73E-135 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 Gene3D G3DSA:3.40.50.150 183 473 2.8E-62 T 28-03-2018 hmeg3_RS13005 054880fc61a664e5c74fbfc8d0808b91 520 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 285 291 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 21 694 2.5E-267 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 Pfam PF00771 FHIPEP family 32 686 2.8E-267 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 159 1.2E-53 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 192 209 1.2E-53 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 76 95 1.2E-53 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 243 257 1.2E-53 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 162 180 1.2E-53 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 39 52 1.2E-53 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 148 171 - T 28-03-2018 IPR025505 FHIPEP conserved site hmeg3_RS08145 1a502918ea4c00122b82e24fd3fd43a1 699 PIRSF PIRSF005419 6 699 2.3E-250 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS01265 1e86a99a991b0a3c09287faa3a753352 410 SUPERFAMILY SSF58104 98 385 1.28E-65 T 28-03-2018 hmeg3_RS01265 1e86a99a991b0a3c09287faa3a753352 410 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 191 345 3.3E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01265 1e86a99a991b0a3c09287faa3a753352 410 SMART SM00283 131 378 1.7E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01265 1e86a99a991b0a3c09287faa3a753352 410 Gene3D G3DSA:1.10.287.950 83 186 1.1E-14 T 28-03-2018 hmeg3_RS01265 1e86a99a991b0a3c09287faa3a753352 410 Gene3D G3DSA:1.10.287.950 187 382 2.6E-48 T 28-03-2018 hmeg3_RS02980 f119f33dac427d2083e55644e566893b 133 SUPERFAMILY SSF55961 7 133 2.75E-34 T 28-03-2018 hmeg3_RS02980 f119f33dac427d2083e55644e566893b 133 Gene3D G3DSA:3.30.530.20 10 133 9.6E-17 T 28-03-2018 IPR023393 START-like domain hmeg3_RS23365 cc1fd334e6b88ec946c5d717e7c9437d 469 Pfam PF01266 FAD dependent oxidoreductase 60 420 1.1E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS23365 cc1fd334e6b88ec946c5d717e7c9437d 469 Gene3D G3DSA:3.40.50.720 57 428 1.2E-33 T 28-03-2018 hmeg3_RS23365 cc1fd334e6b88ec946c5d717e7c9437d 469 SUPERFAMILY SSF51905 381 435 1.25E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23365 cc1fd334e6b88ec946c5d717e7c9437d 469 SUPERFAMILY SSF51905 59 286 1.25E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08675 7187dfd2718876d05852ed24e787cf7e 193 SUPERFAMILY SSF160930 5 162 9.81E-63 T 28-03-2018 hmeg3_RS08675 7187dfd2718876d05852ed24e787cf7e 193 PIRSF PIRSF003159 1 183 5.1E-91 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 hmeg3_RS08675 7187dfd2718876d05852ed24e787cf7e 193 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 185 45.088 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 hmeg3_RS08675 7187dfd2718876d05852ed24e787cf7e 193 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 173 2.0E-63 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 hmeg3_RS08675 7187dfd2718876d05852ed24e787cf7e 193 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 174 3.7E-84 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 224 233 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 Pfam PF00155 Aminotransferase class I and II 35 356 2.1E-56 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 367 62.05 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 SUPERFAMILY SSF53383 9 364 3.63E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 364 6.4E-108 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 Gene3D G3DSA:3.90.1150.10 256 362 6.7E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS17985 79ed23350dd29d180a7e5aac0a8c8b95 368 Gene3D G3DSA:3.40.640.10 49 255 1.7E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS17915 882ee35db3918371a1f33b8fbcb17216 108 Gene3D G3DSA:3.30.1310.10 1 108 3.9E-42 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family hmeg3_RS17915 882ee35db3918371a1f33b8fbcb17216 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 1.7E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family hmeg3_RS17915 882ee35db3918371a1f33b8fbcb17216 108 PIRSF PIRSF004555 2 108 9.5E-38 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family hmeg3_RS17915 882ee35db3918371a1f33b8fbcb17216 108 SUPERFAMILY SSF82607 10 102 5.49E-35 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family hmeg3_RS17915 882ee35db3918371a1f33b8fbcb17216 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 4.8E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family hmeg3_RS17915 882ee35db3918371a1f33b8fbcb17216 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 22.882 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SUPERFAMILY SSF48452 235 369 1.37E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SUPERFAMILY SSF48452 5 276 4.36E-46 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF13844 Glycosyl transferase family 41 427 580 1.3E-35 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF13844 Glycosyl transferase family 41 588 780 3.8E-48 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.25.40.10 247 295 6.9E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.25.40.10 309 579 2.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF13371 Tetratricopeptide repeat 255 310 4.8E-9 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF13424 Tetratricopeptide repeat 140 204 9.7E-10 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:3.40.50.2000 580 764 2.4E-30 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.20.58.280 220 246 6.1E-5 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 5 38 0.046 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 243 276 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 175 208 0.0018 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 209 242 0.34 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 107 140 5.4E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 311 344 0.0015 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 277 310 3.4E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 39 72 0.61 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 141 174 9.7E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SMART SM00028 73 106 2.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF00515 Tetratricopeptide repeat 107 139 3.2E-7 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.25.40.10 65 123 5.8E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.25.40.10 138 189 4.0E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF13432 Tetratricopeptide repeat 11 71 0.0055 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 SUPERFAMILY SSF53756 562 755 7.53E-6 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Pfam PF13181 Tetratricopeptide repeat 210 242 0.12 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.25.40.10 4 64 1.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.25.40.10 190 219 5.4E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.10.287.1110 296 308 8.0E-8 T 28-03-2018 hmeg3_RS02805 ab338ac6a930eb22b725f688049b66f5 797 Gene3D G3DSA:1.10.287.1110 124 137 1.5E-9 T 28-03-2018 hmeg3_RS23685 361e2a2d5b4eb672dfd058880d3f2b5c 267 Pfam PF00005 ABC transporter 27 164 2.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23685 361e2a2d5b4eb672dfd058880d3f2b5c 267 Gene3D G3DSA:3.40.50.300 2 231 1.5E-53 T 28-03-2018 hmeg3_RS23685 361e2a2d5b4eb672dfd058880d3f2b5c 267 SUPERFAMILY SSF52540 5 212 9.08E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23685 361e2a2d5b4eb672dfd058880d3f2b5c 267 SMART SM00382 35 213 2.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 SUPERFAMILY SSF55931 104 470 3.24E-136 T 28-03-2018 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 Pfam PF00120 Glutamine synthetase, catalytic domain 105 468 2.5E-137 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 SMART SM01230 104 381 1.2E-146 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 Gene3D G3DSA:3.10.20.70 4 106 3.2E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 6.5E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 Gene3D G3DSA:3.30.590.10 107 460 1.2E-121 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 470 1.6E-200 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 hmeg3_RS15470 8aa1709d85ebbb5dccb278d6daad17f9 471 SUPERFAMILY SSF54368 4 101 2.09E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 hmeg3_RS10485 262fcfa19e19366fe6b3d2e0b3b43b61 166 SMART SM00972 105 163 6.4E-21 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS10485 262fcfa19e19366fe6b3d2e0b3b43b61 166 Pfam PF05229 Spore Coat Protein U domain 33 163 1.6E-34 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 54 8.0E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 Pfam PF01467 Cytidylyltransferase-like 5 133 5.7E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 5.8E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 5.8E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 5.8E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 5.8E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 5.8E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.221 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 Gene3D G3DSA:3.40.50.620 1 158 2.2E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 SUPERFAMILY SSF52374 4 156 3.49E-44 T 28-03-2018 hmeg3_RS03380 241b9f08c356eaae2abe6dea5b61938f 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 1.0E-56 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 hmeg3_RS04210 41e2c711b5e80d8e2b50b30363bb7d11 146 Pfam PF12680 SnoaL-like domain 17 114 2.0E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS04210 41e2c711b5e80d8e2b50b30363bb7d11 146 SUPERFAMILY SSF54427 9 124 5.12E-23 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS04210 41e2c711b5e80d8e2b50b30363bb7d11 146 Gene3D G3DSA:3.10.450.50 1 130 2.2E-20 T 28-03-2018 hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 Pfam PF00248 Aldo/keto reductase family 587 770 5.1E-24 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 SUPERFAMILY SSF51905 480 543 2.11E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 SUPERFAMILY SSF51905 10 250 2.11E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 SUPERFAMILY SSF51430 572 832 1.03E-32 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 Gene3D G3DSA:3.50.50.60 8 546 2.9E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 Pfam PF05199 GMC oxidoreductase 405 534 5.1E-24 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 hmeg3_RS07795 9571514b103ea202e0afff56224d5682 835 Gene3D G3DSA:3.20.20.100 562 835 7.6E-31 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS07060 e87ae4298c295ac1b63bc0ace4450bed 240 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 176 1.3E-60 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS07060 e87ae4298c295ac1b63bc0ace4450bed 240 SMART SM00479 2 174 7.0E-44 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS07060 e87ae4298c295ac1b63bc0ace4450bed 240 Gene3D G3DSA:3.30.420.10 2 180 3.9E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS07060 e87ae4298c295ac1b63bc0ace4450bed 240 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 232 6.1E-88 T 28-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS07060 e87ae4298c295ac1b63bc0ace4450bed 240 SUPERFAMILY SSF53098 1 175 5.81E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS07060 e87ae4298c295ac1b63bc0ace4450bed 240 Pfam PF00929 Exonuclease 4 165 2.8E-35 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS02245 6ccabb91bf2566fb1c3be7cb46f345da 109 Pfam PF13663 Domain of unknown function (DUF4148) 1 65 3.2E-10 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 Pfam PF00347 Ribosomal protein L6 12 82 6.3E-14 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 Pfam PF00347 Ribosomal protein L6 90 164 6.3E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 SUPERFAMILY SSF56053 1 82 7.2E-23 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.3E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.3E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.3E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.813 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 PIRSF PIRSF002162 1 177 1.0E-48 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 Gene3D G3DSA:3.90.930.12 86 177 2.1E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 SUPERFAMILY SSF56053 83 177 4.97E-36 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 8.8E-74 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 hmeg3_RS22785 b4a9faef4b466d0f8716576c692fec37 177 Gene3D G3DSA:3.90.930.12 5 85 5.2E-25 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS07800 a94029749d864c4b073fe0aecbf3f7a3 311 SUPERFAMILY SSF53448 23 246 1.13E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS07800 a94029749d864c4b073fe0aecbf3f7a3 311 Gene3D G3DSA:3.90.550.10 2 262 5.8E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS07800 a94029749d864c4b073fe0aecbf3f7a3 311 Pfam PF00535 Glycosyl transferase family 2 27 190 1.3E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS09110 f10c50207afe747b651cc17b0d79d8a8 123 Gene3D G3DSA:2.102.10.10 1 122 9.5E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS09110 f10c50207afe747b651cc17b0d79d8a8 123 Pfam PF00355 Rieske [2Fe-2S] domain 6 95 2.7E-8 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS09110 f10c50207afe747b651cc17b0d79d8a8 123 SUPERFAMILY SSF50022 6 117 1.57E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS24105 43cb937963378423e298eb7296fc306a 284 Gene3D G3DSA:3.20.10.10 135 283 1.8E-34 T 28-03-2018 hmeg3_RS24105 43cb937963378423e298eb7296fc306a 284 SUPERFAMILY SSF56752 5 278 7.72E-76 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS24105 43cb937963378423e298eb7296fc306a 284 Pfam PF01063 Amino-transferase class IV 32 254 1.5E-42 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS24105 43cb937963378423e298eb7296fc306a 284 Gene3D G3DSA:3.30.470.10 1 134 4.7E-33 T 28-03-2018 hmeg3_RS10335 8966b54cdf0e967750f6d1dc7102fa1b 167 Pfam PF13420 Acetyltransferase (GNAT) domain 8 141 7.0E-18 T 28-03-2018 hmeg3_RS10335 8966b54cdf0e967750f6d1dc7102fa1b 167 Gene3D G3DSA:3.40.630.30 3 167 4.9E-32 T 28-03-2018 hmeg3_RS10335 8966b54cdf0e967750f6d1dc7102fa1b 167 SUPERFAMILY SSF55729 5 165 2.19E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS04680 21e5a8a8b812e68301b2d91957009e3d 249 SUPERFAMILY SSF161098 23 225 1.11E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04680 21e5a8a8b812e68301b2d91957009e3d 249 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 22 91 4.3E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS04680 21e5a8a8b812e68301b2d91957009e3d 249 Gene3D G3DSA:1.10.3720.10 2 235 4.2E-39 T 28-03-2018 hmeg3_RS04680 21e5a8a8b812e68301b2d91957009e3d 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 231 2.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 Gene3D G3DSA:2.40.128.20 35 194 5.1E-40 T 28-03-2018 IPR012674 Calycin hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 SUPERFAMILY SSF50814 30 193 1.84E-44 T 28-03-2018 IPR012674 Calycin hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 Pfam PF08212 Lipocalin-like domain 46 193 7.0E-51 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 PRINTS PR01171 Bacterial lipocalin signature 46 60 3.4E-11 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 PRINTS PR01171 Bacterial lipocalin signature 83 92 3.4E-11 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 PRINTS PR01171 Bacterial lipocalin signature 155 166 3.4E-11 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 PRINTS PR01171 Bacterial lipocalin signature 182 192 3.4E-11 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 ProSitePatterns PS00213 Lipocalin signature. 47 58 - T 28-03-2018 IPR022272 Lipocalin family conserved site hmeg3_RS24170 6e995a8632a0bc633323af606f632b56 194 PIRSF PIRSF036893 8 194 5.9E-58 T 28-03-2018 IPR022271 Lipocalin, ApoD type hmeg3_RS21460 7125c5c4cb0d3b11b5f913c44e4eeda8 318 Hamap MF_00301 Homoserine kinase [thrB]. 1 318 158.301 T 28-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 hmeg3_RS21460 7125c5c4cb0d3b11b5f913c44e4eeda8 318 SUPERFAMILY SSF56112 5 310 1.46E-76 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS21460 7125c5c4cb0d3b11b5f913c44e4eeda8 318 Gene3D G3DSA:3.90.1200.10 105 314 2.9E-23 T 28-03-2018 hmeg3_RS21460 7125c5c4cb0d3b11b5f913c44e4eeda8 318 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 307 9.4E-103 T 28-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 hmeg3_RS21460 7125c5c4cb0d3b11b5f913c44e4eeda8 318 Gene3D G3DSA:3.30.200.20 1 102 5.3E-22 T 28-03-2018 hmeg3_RS21460 7125c5c4cb0d3b11b5f913c44e4eeda8 318 Pfam PF01636 Phosphotransferase enzyme family 27 256 1.0E-31 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase hmeg3_RS20485 e92309419718aa93df43bdc2de2616a9 176 Pfam PF04390 Lipopolysaccharide-assembly 38 163 1.7E-13 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 hmeg3_RS20485 e92309419718aa93df43bdc2de2616a9 176 Gene3D G3DSA:3.30.160.150 26 176 1.9E-42 T 28-03-2018 hmeg3_RS20485 e92309419718aa93df43bdc2de2616a9 176 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 11 168 23.902 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Pfam PF03979 Sigma-70 factor, region 1.1 245 323 1.7E-28 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 SUPERFAMILY SSF88946 358 695 2.67E-101 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Pfam PF04542 Sigma-70 region 2 630 697 1.0E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 652 665 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 624 849 2.6E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 SUPERFAMILY SSF88659 758 859 2.83E-27 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Gene3D G3DSA:1.10.10.10 791 861 2.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Gene3D G3DSA:1.10.10.10 698 748 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 821 847 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Pfam PF00140 Sigma-70 factor, region 1.2 341 373 5.2E-14 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Pfam PF04539 Sigma-70 region 3 707 783 2.0E-23 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Pfam PF04546 Sigma-70, non-essential region 382 597 3.3E-66 T 28-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Gene3D G3DSA:1.10.601.10 1 357 1.4E-8 T 28-03-2018 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Gene3D G3DSA:1.10.601.10 358 697 2.8E-106 T 28-03-2018 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 237 861 41.824 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 624 860 2.5E-117 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 PRINTS PR00046 Major sigma-70 factor signature 652 665 1.4E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 PRINTS PR00046 Major sigma-70 factor signature 800 812 1.4E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 PRINTS PR00046 Major sigma-70 factor signature 821 836 1.4E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 PRINTS PR00046 Major sigma-70 factor signature 836 847 1.4E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 PRINTS PR00046 Major sigma-70 factor signature 676 684 1.4E-30 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 SUPERFAMILY SSF88659 701 775 4.67E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS19485 e5ebcd129f6db98ece80f3303c3e738e 863 Pfam PF04545 Sigma-70, region 4 797 849 7.3E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS00430 1e3cce7fe535c3c081e41ee1d1704dce 550 Gene3D G3DSA:3.90.76.10 59 168 3.2E-24 T 28-03-2018 hmeg3_RS00430 1e3cce7fe535c3c081e41ee1d1704dce 550 PIRSF PIRSF002741 61 544 6.7E-67 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS00430 1e3cce7fe535c3c081e41ee1d1704dce 550 Gene3D G3DSA:3.40.190.10 169 317 8.4E-29 T 28-03-2018 hmeg3_RS00430 1e3cce7fe535c3c081e41ee1d1704dce 550 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 437 2.3E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS00430 1e3cce7fe535c3c081e41ee1d1704dce 550 Gene3D G3DSA:3.10.105.10 318 522 4.2E-34 T 28-03-2018 hmeg3_RS00430 1e3cce7fe535c3c081e41ee1d1704dce 550 SUPERFAMILY SSF53850 25 549 7.6E-100 T 28-03-2018 hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 238 550 9.1E-27 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 Pfam PF13609 Gram-negative porin 677 991 4.7E-15 T 28-03-2018 hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 Gene3D G3DSA:2.40.160.50 206 587 6.2E-47 T 28-03-2018 hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 Gene3D G3DSA:2.40.160.10 589 1028 7.0E-30 T 28-03-2018 hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 Pfam PF08479 POTRA domain, ShlB-type 100 174 4.2E-18 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 Gene3D G3DSA:3.10.20.310 105 174 7.8E-17 T 28-03-2018 hmeg3_RS20675 645b65751435e5ef6da275114bdefbc3 1028 SUPERFAMILY SSF56935 614 1028 2.2E-31 T 28-03-2018 hmeg3_RS24310 6807b29de9c9237805c973d6b35a2b3e 107 Gene3D G3DSA:1.10.260.40 10 107 5.8E-13 T 28-03-2018 hmeg3_RS24310 6807b29de9c9237805c973d6b35a2b3e 107 SUPERFAMILY SSF47413 10 77 3.66E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS24310 6807b29de9c9237805c973d6b35a2b3e 107 SMART SM00530 14 73 2.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS24310 6807b29de9c9237805c973d6b35a2b3e 107 Pfam PF13560 Helix-turn-helix domain 14 70 2.9E-7 T 28-03-2018 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 9.4E-32 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 SUPERFAMILY SSF54719 88 201 1.19E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 3.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 3.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 3.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.0E-25 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 PIRSF PIRSF000349 1 203 8.2E-80 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 197 1.9E-37 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 Gene3D G3DSA:1.10.287.990 20 89 2.0E-28 T 28-03-2018 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 SUPERFAMILY SSF46609 1 90 2.49E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS22175 542fb880ed3f2d55031850fd54f931f9 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 hmeg3_RS11795 d7da629f253d17d7d94778a76925783f 150 SUPERFAMILY SSF54427 25 127 1.7E-20 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS11795 d7da629f253d17d7d94778a76925783f 150 Gene3D G3DSA:3.10.450.50 5 149 5.2E-17 T 28-03-2018 hmeg3_RS11795 d7da629f253d17d7d94778a76925783f 150 Pfam PF12680 SnoaL-like domain 27 86 9.6E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS14750 cf7303db81318dc0b900b213990d30ba 573 Gene3D G3DSA:3.40.50.300 292 571 2.6E-32 T 28-03-2018 hmeg3_RS14750 cf7303db81318dc0b900b213990d30ba 573 Gene3D G3DSA:3.40.50.300 2 267 1.3E-40 T 28-03-2018 hmeg3_RS14750 cf7303db81318dc0b900b213990d30ba 573 SUPERFAMILY SSF52540 4 561 4.65E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14750 cf7303db81318dc0b900b213990d30ba 573 Pfam PF13361 UvrD-like helicase C-terminal domain 495 559 1.5E-21 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 hmeg3_RS14750 cf7303db81318dc0b900b213990d30ba 573 Pfam PF13245 AAA domain 12 246 2.0E-25 T 28-03-2018 hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 Pfam PF00128 Alpha amylase, catalytic domain 34 105 1.1E-14 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 SUPERFAMILY SSF51445 256 493 9.61E-126 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 SUPERFAMILY SSF51445 543 846 9.61E-126 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 SUPERFAMILY SSF51445 16 155 9.61E-126 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 SMART SM00642 14 494 4.3E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 Gene3D G3DSA:3.20.20.80 18 848 1.1E-108 T 28-03-2018 hmeg3_RS11350 06af651a05191b7be83aeb7dbcb088b8 973 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 14 956 2.7E-288 T 28-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 Pfam PF13602 Zinc-binding dehydrogenase 190 324 3.8E-20 T 28-03-2018 hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 Gene3D G3DSA:3.40.50.720 139 293 6.4E-32 T 28-03-2018 hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 SUPERFAMILY SSF50129 1 148 5.63E-36 T 28-03-2018 IPR011032 GroES-like hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 Gene3D G3DSA:3.90.180.10 1 138 2.1E-39 T 28-03-2018 hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 SUPERFAMILY SSF51735 118 291 1.83E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 SMART SM00829 10 324 7.9E-31 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS02750 00d214df6ad935bb2a39c64693b34e18 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 85 1.4E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 hmeg3_RS24420 14f8ee241d54b9ff7a07a85db395d3eb 502 Gene3D G3DSA:3.90.76.10 40 181 9.5E-37 T 28-03-2018 hmeg3_RS24420 14f8ee241d54b9ff7a07a85db395d3eb 502 PIRSF PIRSF002741 5 501 2.7E-110 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS24420 14f8ee241d54b9ff7a07a85db395d3eb 502 Gene3D G3DSA:3.10.105.10 277 475 3.3E-51 T 28-03-2018 hmeg3_RS24420 14f8ee241d54b9ff7a07a85db395d3eb 502 Gene3D G3DSA:3.40.190.10 182 276 5.4E-27 T 28-03-2018 hmeg3_RS24420 14f8ee241d54b9ff7a07a85db395d3eb 502 SUPERFAMILY SSF53850 32 496 7.24E-128 T 28-03-2018 hmeg3_RS24420 14f8ee241d54b9ff7a07a85db395d3eb 502 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 423 1.3E-84 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS23935 0859e196dba415ae0201d2c2bcb5c765 209 Gene3D G3DSA:3.40.50.880 1 206 1.9E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS23935 0859e196dba415ae0201d2c2bcb5c765 209 SUPERFAMILY SSF52317 1 175 1.91E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS23935 0859e196dba415ae0201d2c2bcb5c765 209 Pfam PF01965 DJ-1/PfpI family 2 157 7.3E-11 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS08975 c3ed1db6d23ff606fbcae1ac977d2101 249 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 167 1.6E-73 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 hmeg3_RS08975 c3ed1db6d23ff606fbcae1ac977d2101 249 SUPERFAMILY SSF51161 3 175 7.21E-57 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS08975 c3ed1db6d23ff606fbcae1ac977d2101 249 Gene3D G3DSA:1.10.3130.10 1 51 3.3E-26 T 28-03-2018 hmeg3_RS08975 c3ed1db6d23ff606fbcae1ac977d2101 249 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 6.8E-7 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS08975 c3ed1db6d23ff606fbcae1ac977d2101 249 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 151 3.0E-7 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS08975 c3ed1db6d23ff606fbcae1ac977d2101 249 Gene3D G3DSA:2.160.10.10 52 226 1.2E-40 T 28-03-2018 hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 SUPERFAMILY SSF56042 173 343 9.42E-61 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 336 1.5E-140 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 SUPERFAMILY SSF55326 9 172 2.99E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 Gene3D G3DSA:3.90.650.10 173 347 1.0E-62 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 179 342 2.3E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 166 8.5E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 345 47.141 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 hmeg3_RS20275 259d0d8020d1706f30d4be81b25fe2fe 347 Gene3D G3DSA:3.30.1330.10 36 163 2.9E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 SMART SM00382 373 583 1.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 576 597 1.3E-11 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 Gene3D G3DSA:1.10.3470.10 28 306 5.6E-41 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 Pfam PF00005 ABC transporter 365 526 1.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 302 2.2E-33 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 SUPERFAMILY SSF52540 347 596 1.92E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01095 84d526f82bdf66f6449a4359bd12b392 600 Gene3D G3DSA:3.40.50.300 331 597 3.2E-60 T 28-03-2018 hmeg3_RS11840 f5e3d2e0bce4f007da2f45e600bba094 89 Pfam PF02583 Metal-sensitive transcriptional repressor 7 86 3.4E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 hmeg3_RS16900 ba823f4df76b98fc7eddbc18a64e1c25 260 Gene3D G3DSA:3.40.50.10090 7 129 4.5E-20 T 28-03-2018 hmeg3_RS16900 ba823f4df76b98fc7eddbc18a64e1c25 260 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 242 2.5E-32 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16900 ba823f4df76b98fc7eddbc18a64e1c25 260 SUPERFAMILY SSF69618 8 257 3.53E-41 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 hmeg3_RS16900 ba823f4df76b98fc7eddbc18a64e1c25 260 Gene3D G3DSA:3.40.50.10090 130 259 2.8E-14 T 28-03-2018 hmeg3_RS09490 1dfa8d6e7b4d94d0f1cb1a4a704edfc9 246 Pfam PF00005 ABC transporter 23 160 4.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS09490 1dfa8d6e7b4d94d0f1cb1a4a704edfc9 246 Gene3D G3DSA:3.40.50.300 1 223 7.1E-60 T 28-03-2018 hmeg3_RS09490 1dfa8d6e7b4d94d0f1cb1a4a704edfc9 246 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS09490 1dfa8d6e7b4d94d0f1cb1a4a704edfc9 246 SMART SM00382 31 210 1.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS09490 1dfa8d6e7b4d94d0f1cb1a4a704edfc9 246 SUPERFAMILY SSF52540 5 238 4.23E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10555 7ba57557670b197c80237429b413732d 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 333 2.3E-37 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS10555 7ba57557670b197c80237429b413732d 358 Gene3D G3DSA:1.10.3470.10 47 338 2.9E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS06820 253b6280aabea920df91de6777467eaf 268 SUPERFAMILY SSF56317 2 266 5.1E-80 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS06820 253b6280aabea920df91de6777467eaf 268 Pfam PF00795 Carbon-nitrogen hydrolase 6 257 4.2E-53 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS06820 253b6280aabea920df91de6777467eaf 268 Gene3D G3DSA:3.60.110.10 1 268 3.3E-76 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 SUPERFAMILY SSF54211 143 281 5.31E-51 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 Gene3D G3DSA:3.30.230.20 1 127 5.1E-47 T 28-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 SUPERFAMILY SSF54211 3 125 7.13E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 279 1.3E-105 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 283 45.468 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 301 1.5E-119 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS21975 f152bd0054c6b407bd4571b3071496c3 311 Gene3D G3DSA:3.30.1700.10 128 302 5.8E-67 T 28-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 hmeg3_RS15955 c3cc4c2dd376a6ba5bcc7fd5b6482714 488 SUPERFAMILY SSF56954 6 40 1.03E-112 T 28-03-2018 hmeg3_RS15955 c3cc4c2dd376a6ba5bcc7fd5b6482714 488 SUPERFAMILY SSF56954 63 476 1.03E-112 T 28-03-2018 hmeg3_RS15955 c3cc4c2dd376a6ba5bcc7fd5b6482714 488 Gene3D G3DSA:1.20.1600.10 25 479 7.0E-106 T 28-03-2018 hmeg3_RS15955 c3cc4c2dd376a6ba5bcc7fd5b6482714 488 Pfam PF02321 Outer membrane efflux protein 78 264 2.1E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS15955 c3cc4c2dd376a6ba5bcc7fd5b6482714 488 Pfam PF02321 Outer membrane efflux protein 287 471 6.1E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS15955 c3cc4c2dd376a6ba5bcc7fd5b6482714 488 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 473 4.6E-137 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS02660 5db29ba5756e6e2bfc45df827a3ad510 247 SUPERFAMILY SSF161098 13 233 6.93E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02660 5db29ba5756e6e2bfc45df827a3ad510 247 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 88 1.2E-12 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS02660 5db29ba5756e6e2bfc45df827a3ad510 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 58 241 4.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02660 5db29ba5756e6e2bfc45df827a3ad510 247 Gene3D G3DSA:1.10.3720.10 1 247 1.4E-42 T 28-03-2018 hmeg3_RS08220 7a08f2def1993707fec7f20ba88fc76c 219 Pfam PF02107 Flagellar L-ring protein 43 218 1.9E-51 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS08220 7a08f2def1993707fec7f20ba88fc76c 219 PRINTS PR01008 Flagellar L-ring protein signature 159 175 1.2E-18 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS08220 7a08f2def1993707fec7f20ba88fc76c 219 PRINTS PR01008 Flagellar L-ring protein signature 180 194 1.2E-18 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS08220 7a08f2def1993707fec7f20ba88fc76c 219 PRINTS PR01008 Flagellar L-ring protein signature 133 148 1.2E-18 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS08220 7a08f2def1993707fec7f20ba88fc76c 219 PRINTS PR01008 Flagellar L-ring protein signature 65 77 1.2E-18 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS08220 7a08f2def1993707fec7f20ba88fc76c 219 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 217 23.455 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 hmeg3_RS13485 270caa216f690536047252de9155b658 218 Pfam PF01323 DSBA-like thioredoxin domain 6 208 1.2E-35 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 hmeg3_RS13485 270caa216f690536047252de9155b658 218 Gene3D G3DSA:3.40.30.10 4 210 1.1E-50 T 28-03-2018 hmeg3_RS13485 270caa216f690536047252de9155b658 218 SUPERFAMILY SSF52833 4 214 7.94E-47 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS21605 449c498e742be69d2da2abdccb687062 379 SUPERFAMILY SSF53822 29 371 6.39E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS21605 449c498e742be69d2da2abdccb687062 379 Gene3D G3DSA:3.40.50.2300 28 223 1.2E-20 T 28-03-2018 hmeg3_RS21605 449c498e742be69d2da2abdccb687062 379 Pfam PF13458 Periplasmic binding protein 31 364 2.6E-35 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS21605 449c498e742be69d2da2abdccb687062 379 Gene3D G3DSA:3.40.50.2300 224 357 1.4E-15 T 28-03-2018 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 7.8E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 SUPERFAMILY SSF52172 12 162 3.13E-33 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 Gene3D G3DSA:1.10.10.10 137 206 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 Pfam PF00072 Response regulator receiver domain 12 121 3.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 SMART SM00421 145 202 3.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 SUPERFAMILY SSF46894 144 203 6.8E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 Gene3D G3DSA:3.40.50.2300 1 136 2.5E-30 T 28-03-2018 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05425 69f633bb3bbbcbf68a070de720d9c6b1 210 SMART SM00448 10 121 3.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18390 f26eca06249513d35f9f70bb6d4e02f2 69 SUPERFAMILY SSF158997 3 54 1.83E-20 T 28-03-2018 hmeg3_RS18390 f26eca06249513d35f9f70bb6d4e02f2 69 Pfam PF03966 Trm112p-like protein 4 41 1.0E-12 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 hmeg3_RS18390 f26eca06249513d35f9f70bb6d4e02f2 69 Gene3D G3DSA:2.20.25.10 8 53 2.2E-21 T 28-03-2018 hmeg3_RS18390 f26eca06249513d35f9f70bb6d4e02f2 69 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 26.827 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 Pfam PF12833 Helix-turn-helix domain 246 321 7.8E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 SUPERFAMILY SSF46689 223 274 3.79E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 Gene3D G3DSA:1.10.10.60 279 332 1.7E-11 T 28-03-2018 hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 SMART SM00342 240 323 1.0E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 SUPERFAMILY SSF46689 276 326 4.48E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 Pfam PF06719 AraC-type transcriptional regulator N-terminus 61 211 1.3E-48 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal hmeg3_RS22140 002969c9b7b6913c2345fbd7cc0d8a52 334 Gene3D G3DSA:1.10.10.60 219 278 1.4E-14 T 28-03-2018 hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 371 5.0E-23 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 SMART SM00267 210 377 1.8E-25 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 SUPERFAMILY SSF141868 393 639 5.23E-92 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 Gene3D G3DSA:3.30.70.270 215 384 5.3E-35 T 28-03-2018 hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 SMART SM00052 387 632 3.9E-121 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 Gene3D G3DSA:3.20.20.450 385 640 7.0E-102 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 SUPERFAMILY SSF55073 226 378 3.69E-25 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 Pfam PF00563 EAL domain 393 627 8.0E-72 T 28-03-2018 IPR001633 EAL domain hmeg3_RS18520 3318db2679e4ade3cd92de3030720f60 640 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 218 372 1.7E-15 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09400 e9c02897da205d56002bb7b3f9c567f5 333 PIRSF PIRSF026166 1 332 4.4E-133 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter hmeg3_RS09400 e9c02897da205d56002bb7b3f9c567f5 333 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 9 317 4.5E-98 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter hmeg3_RS04345 d0106b7fbc0d4b2b95f5426cc0c36463 157 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 145 3.1E-34 T 28-03-2018 IPR002178 PTS EIIA type-2 domain hmeg3_RS04345 d0106b7fbc0d4b2b95f5426cc0c36463 157 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain hmeg3_RS04345 d0106b7fbc0d4b2b95f5426cc0c36463 157 Gene3D G3DSA:3.40.930.10 2 149 2.5E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 hmeg3_RS04345 d0106b7fbc0d4b2b95f5426cc0c36463 157 SUPERFAMILY SSF55804 2 146 1.96E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 SMART SM00919 173 410 9.6E-137 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 SUPERFAMILY SSF53659 439 766 1.81E-91 T 28-03-2018 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Pfam PF00390 Malic enzyme, N-terminal domain 29 161 5.8E-27 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 SMART SM01274 28 161 1.6E-81 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 SUPERFAMILY SSF53223 20 171 4.1E-53 T 28-03-2018 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Gene3D G3DSA:3.40.50.10380 15 170 2.2E-36 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 PIRSF PIRSF036684 8 770 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Pfam PF03949 Malic enzyme, NAD binding domain 175 369 1.1E-23 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Pfam PF01515 Phosphate acetyl/butaryl transferase 439 762 2.6E-99 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Pfam PF12434 Malate dehydrogenase enzyme 8 26 5.9E-6 T 28-03-2018 IPR032683 Malate dehydrogenase enzyme, N-terminal hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 SUPERFAMILY SSF51735 173 465 2.78E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Gene3D G3DSA:3.40.50.720 171 458 1.6E-83 T 28-03-2018 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 PRINTS PR00072 Malic enzyme signature 169 185 2.7E-5 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 PRINTS PR00072 Malic enzyme signature 200 216 2.7E-5 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 PRINTS PR00072 Malic enzyme signature 90 112 2.7E-5 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 hmeg3_RS07200 7f8d49ed7d333887391e177be54cd853 770 Gene3D G3DSA:3.40.718.10 459 734 2.7E-53 T 28-03-2018 hmeg3_RS23190 2a33fb3188be6a1894f1b58d3d584974 390 Gene3D G3DSA:3.40.1090.10 10 240 2.3E-43 T 28-03-2018 hmeg3_RS23190 2a33fb3188be6a1894f1b58d3d584974 390 Pfam PF12536 Patatin phospholipase 268 362 5.1E-22 T 28-03-2018 IPR021095 Protein of unknown function DUF3734 hmeg3_RS23190 2a33fb3188be6a1894f1b58d3d584974 390 SUPERFAMILY SSF52151 19 94 3.49E-47 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS23190 2a33fb3188be6a1894f1b58d3d584974 390 SUPERFAMILY SSF52151 135 266 3.49E-47 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS23190 2a33fb3188be6a1894f1b58d3d584974 390 Pfam PF01734 Patatin-like phospholipase 24 232 2.3E-28 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 hmeg3_RS08080 7c3d880a0b2f82b5bfd6a077c8485bec 415 SUPERFAMILY SSF103473 20 407 1.7E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS08080 7c3d880a0b2f82b5bfd6a077c8485bec 415 Gene3D G3DSA:1.20.1250.20 221 408 1.1E-11 T 28-03-2018 hmeg3_RS08080 7c3d880a0b2f82b5bfd6a077c8485bec 415 Pfam PF07690 Major Facilitator Superfamily 39 354 9.8E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS08080 7c3d880a0b2f82b5bfd6a077c8485bec 415 Gene3D G3DSA:1.20.1250.20 24 220 4.0E-26 T 28-03-2018 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 SMART SM01329 5 354 1.1E-181 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 353 2.3E-85 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 SUPERFAMILY SSF53659 3 358 1.3E-116 T 28-03-2018 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 Gene3D G3DSA:3.40.718.10 212 358 1.0E-54 T 28-03-2018 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 Gene3D G3DSA:3.40.718.10 1 211 1.4E-63 T 28-03-2018 hmeg3_RS16150 326860911ccb266c04671da87df1dd64 358 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 358 4.2E-169 T 28-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Pfam PF00563 EAL domain 533 767 2.8E-72 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Pfam PF14827 Double sensory domain of two-component sensor kinase 40 268 1.5E-23 T 28-03-2018 IPR029150 Double Cache domain 3 hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 SUPERFAMILY SSF158472 299 347 1.14E-10 T 28-03-2018 hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 355 514 3.9E-39 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 SMART SM00052 527 772 2.5E-109 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Pfam PF00990 Diguanylate cyclase, GGDEF domain 357 512 1.0E-40 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 SUPERFAMILY SSF55073 362 516 1.1E-43 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 SMART SM00304 299 351 6.1E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Gene3D G3DSA:3.30.450.20 49 179 7.5E-4 T 28-03-2018 hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Gene3D G3DSA:3.20.20.450 526 785 4.5E-99 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 SMART SM00267 346 518 6.4E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 SUPERFAMILY SSF141868 533 783 3.4E-89 T 28-03-2018 IPR001633 EAL domain hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Pfam PF00672 HAMP domain 299 345 2.5E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS12825 573c4ab7aad87a8bf74001e507e7ab7a 794 Gene3D G3DSA:3.30.70.270 358 525 1.7E-52 T 28-03-2018 hmeg3_RS21635 045708eebd71c966ecc0c641adb22ff5 309 Pfam PF05661 Protein of unknown function (DUF808) 4 294 5.9E-115 T 28-03-2018 IPR008526 Inner membrane protein YedI hmeg3_RS21635 045708eebd71c966ecc0c641adb22ff5 309 PIRSF PIRSF016660 1 307 3.4E-121 T 28-03-2018 IPR008526 Inner membrane protein YedI hmeg3_RS21995 6af8f2fafdf93a4817aa870a78fad14f 257 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 243 22.079 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 hmeg3_RS21995 6af8f2fafdf93a4817aa870a78fad14f 257 Pfam PF03799 Cell division protein FtsQ 115 235 1.8E-24 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB hmeg3_RS21995 6af8f2fafdf93a4817aa870a78fad14f 257 Pfam PF08478 POTRA domain, FtsQ-type 38 110 1.8E-14 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 13 415 1.3E-153 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 8 436 32.121 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 Pfam PF03129 Anticodon binding domain 351 431 3.2E-9 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 PIRSF PIRSF001549 6 431 2.4E-115 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 SUPERFAMILY SSF55681 13 322 1.19E-101 T 28-03-2018 hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 SUPERFAMILY SSF52954 331 433 3.02E-19 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 Gene3D G3DSA:3.40.50.800 330 445 1.0E-17 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 Gene3D G3DSA:3.30.930.10 12 329 7.2E-72 T 28-03-2018 hmeg3_RS08875 ca07af97f2f903cd0262b07ed49a55e0 449 Pfam PF13393 Histidyl-tRNA synthetase 15 317 1.8E-51 T 28-03-2018 hmeg3_RS16290 cb439dfb9786b02260532065fdd16900 306 Gene3D G3DSA:1.10.3720.10 3 293 2.3E-43 T 28-03-2018 hmeg3_RS16290 cb439dfb9786b02260532065fdd16900 306 SUPERFAMILY SSF161098 89 287 2.35E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS16290 cb439dfb9786b02260532065fdd16900 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 6.4E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11410 bcb8c8fed344bdba05baf789961556ac 187 Pfam PF03992 Antibiotic biosynthesis monooxygenase 9 81 2.1E-9 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain hmeg3_RS11410 bcb8c8fed344bdba05baf789961556ac 187 Gene3D G3DSA:3.30.70.100 1 111 3.5E-17 T 28-03-2018 hmeg3_RS11410 bcb8c8fed344bdba05baf789961556ac 187 SUPERFAMILY SSF54909 7 96 7.89E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS08580 94a3010f7b27319e71260604d854011a 202 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 54 170 3.0E-8 T 28-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component hmeg3_RS08580 94a3010f7b27319e71260604d854011a 202 Pfam PF13470 PIN domain 54 166 1.9E-19 T 28-03-2018 IPR002716 PIN domain hmeg3_RS08580 94a3010f7b27319e71260604d854011a 202 Gene3D G3DSA:3.40.50.1010 53 192 2.7E-10 T 28-03-2018 IPR029060 PIN domain-like hmeg3_RS08580 94a3010f7b27319e71260604d854011a 202 SUPERFAMILY SSF88723 54 173 6.17E-9 T 28-03-2018 IPR029060 PIN domain-like hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 SUPERFAMILY SSF58104 243 515 5.23E-70 T 28-03-2018 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 9.8E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 9.8E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 9.8E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 9.8E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 186 206 9.8E-54 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 SMART SM00283 266 513 1.0E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 Gene3D G3DSA:1.10.287.950 153 323 3.3E-23 T 28-03-2018 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 Gene3D G3DSA:1.10.287.950 324 517 1.9E-45 T 28-03-2018 hmeg3_RS20755 5ba3f7000b3097f2eccdc270682d5d89 562 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 481 1.1E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 34 53 3.3E-13 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 98 117 3.3E-13 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 330 345 3.3E-13 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 373 392 3.3E-13 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 60 79 3.3E-13 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 Gene3D G3DSA:1.20.1340.10 1 67 3.9E-11 T 28-03-2018 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 Gene3D G3DSA:3.90.1150.10 345 461 1.2E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 SUPERFAMILY SSF56059 691 845 1.18E-10 T 28-03-2018 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 32 392 7.6E-60 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 Gene3D G3DSA:3.30.470.20 657 855 2.8E-9 T 28-03-2018 hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 SUPERFAMILY SSF53383 1 455 8.41E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS01540 c37f81f8694de94fa9c1e1f8c72a619e 902 Gene3D G3DSA:3.40.640.10 70 344 2.3E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS19040 5d526f552e1799fddec9c1e2109b1f1d 217 Pfam PF01081 KDPG and KHG aldolase 9 187 4.1E-29 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 hmeg3_RS19040 5d526f552e1799fddec9c1e2109b1f1d 217 SUPERFAMILY SSF51569 5 206 2.38E-54 T 28-03-2018 hmeg3_RS19040 5d526f552e1799fddec9c1e2109b1f1d 217 Gene3D G3DSA:3.20.20.70 4 211 4.3E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS03510 985e141c0c6364de78bf7f6fb95629a6 254 Pfam PF00977 Histidine biosynthesis protein 6 235 5.5E-91 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 hmeg3_RS03510 985e141c0c6364de78bf7f6fb95629a6 254 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 252 48.504 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 hmeg3_RS03510 985e141c0c6364de78bf7f6fb95629a6 254 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 252 8.6E-112 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 hmeg3_RS03510 985e141c0c6364de78bf7f6fb95629a6 254 SUPERFAMILY SSF51366 3 252 4.16E-86 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS03510 985e141c0c6364de78bf7f6fb95629a6 254 Gene3D G3DSA:3.20.20.70 5 248 1.1E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 SUPERFAMILY SSF46785 1 112 1.66E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 Pfam PF03466 LysR substrate binding domain 89 290 7.1E-43 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 Gene3D G3DSA:3.40.190.10 181 268 2.3E-20 T 28-03-2018 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 SUPERFAMILY SSF53850 90 297 6.66E-41 T 28-03-2018 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 4.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 Gene3D G3DSA:1.10.10.10 1 92 4.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS14375 374666644bb9fd8c5f8e2122a9763989 311 Gene3D G3DSA:3.40.190.10 93 180 1.8E-21 T 28-03-2018 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 Gene3D G3DSA:3.40.47.10 1 276 7.8E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 SUPERFAMILY SSF53901 4 275 1.68E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 SUPERFAMILY SSF53901 276 399 7.54E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 Pfam PF00108 Thiolase, N-terminal domain 5 267 1.2E-75 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 3.0E-136 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 400 2.0E-220 T 28-03-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 Gene3D G3DSA:3.40.47.10 277 397 7.2E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 PIRSF PIRSF000429 1 400 9.8E-132 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 hmeg3_RS01160 6a7599fe8b7ad99015c58d0e4d7c8e50 400 Pfam PF02803 Thiolase, C-terminal domain 276 399 1.6E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 hmeg3_RS16215 b1d987bbeae1e506a9c0887390512f0d 523 Gene3D G3DSA:1.20.200.10 210 521 1.8E-96 T 28-03-2018 hmeg3_RS16215 b1d987bbeae1e506a9c0887390512f0d 523 Pfam PF00221 Aromatic amino acid lyase 21 473 2.0E-157 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 hmeg3_RS16215 b1d987bbeae1e506a9c0887390512f0d 523 Gene3D G3DSA:1.10.275.10 6 209 8.6E-62 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal hmeg3_RS16215 b1d987bbeae1e506a9c0887390512f0d 523 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 151 167 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 hmeg3_RS16215 b1d987bbeae1e506a9c0887390512f0d 523 SUPERFAMILY SSF48557 11 519 7.77E-167 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 hmeg3_RS14555 4ec3ead0d0316ca1a6645ed8a795c01e 330 SUPERFAMILY SSF50974 11 325 3.66E-78 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 hmeg3_RS14555 4ec3ead0d0316ca1a6645ed8a795c01e 330 Gene3D G3DSA:2.130.10.10 22 114 6.1E-13 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS14555 4ec3ead0d0316ca1a6645ed8a795c01e 330 Gene3D G3DSA:2.130.10.10 211 329 5.4E-27 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS14555 4ec3ead0d0316ca1a6645ed8a795c01e 330 Gene3D G3DSA:2.130.10.10 115 210 1.1E-20 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS14555 4ec3ead0d0316ca1a6645ed8a795c01e 330 Pfam PF10282 Lactonase, 7-bladed beta-propeller 108 302 5.2E-13 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller hmeg3_RS16420 b6e922f6bf3237161ca770bb809792cb 226 Gene3D G3DSA:3.40.109.10 3 226 2.7E-50 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS16420 b6e922f6bf3237161ca770bb809792cb 226 Pfam PF00881 Nitroreductase family 14 201 1.2E-31 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 hmeg3_RS16420 b6e922f6bf3237161ca770bb809792cb 226 SUPERFAMILY SSF55469 8 223 8.64E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 PRINTS PR00184 Neisseria sp. porin signature 63 88 9.9E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 PRINTS PR00184 Neisseria sp. porin signature 368 392 9.9E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 Pfam PF13609 Gram-negative porin 318 395 2.0E-8 T 28-03-2018 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 Pfam PF13609 Gram-negative porin 7 293 1.1E-41 T 28-03-2018 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 Gene3D G3DSA:2.40.160.10 9 424 2.1E-73 T 28-03-2018 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 SUPERFAMILY SSF56935 253 424 2.04E-73 T 28-03-2018 hmeg3_RS02850 8a5bc8da75a47a9925015982eb7ea16b 424 SUPERFAMILY SSF56935 17 224 2.04E-73 T 28-03-2018 hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 Gene3D G3DSA:1.20.120.530 84 227 2.1E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 Gene3D G3DSA:1.10.10.10 3 83 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 SMART SM00345 22 80 6.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 Pfam PF07729 FCD domain 90 210 6.9E-20 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 SUPERFAMILY SSF48008 85 218 8.11E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 SMART SM00895 90 211 3.9E-9 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 SUPERFAMILY SSF46785 14 84 1.86E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23890 f3e387f02d80a4c0dc3e5602d91ee35a 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 1.1E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS22625 40a0eb7997ad94d84721266131fb7610 219 Gene3D G3DSA:3.40.50.1000 82 216 1.6E-23 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS22625 40a0eb7997ad94d84721266131fb7610 219 Gene3D G3DSA:1.10.150.240 24 81 7.5E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 hmeg3_RS22625 40a0eb7997ad94d84721266131fb7610 219 SUPERFAMILY SSF56784 9 215 2.4E-50 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS22625 40a0eb7997ad94d84721266131fb7610 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 49 187 5.9E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS22625 40a0eb7997ad94d84721266131fb7610 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 188 9.2E-25 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 SUPERFAMILY SSF53850 91 286 4.01E-37 T 28-03-2018 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 Gene3D G3DSA:3.40.190.10 174 261 1.4E-19 T 28-03-2018 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 Gene3D G3DSA:1.10.10.10 1 80 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 Gene3D G3DSA:3.40.190.10 86 173 6.8E-17 T 28-03-2018 hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 Pfam PF03466 LysR substrate binding domain 91 284 7.3E-38 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS12315 1969795765992ff19fcf2096f4e32235 290 SUPERFAMILY SSF46785 1 82 9.98E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16440 7d5331956d1d2b67ebbfa40c8f2f73ea 321 SUPERFAMILY SSF51445 31 104 2.38E-8 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS16440 7d5331956d1d2b67ebbfa40c8f2f73ea 321 SUPERFAMILY SSF51445 135 229 2.38E-8 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS16440 7d5331956d1d2b67ebbfa40c8f2f73ea 321 Gene3D G3DSA:3.20.20.80 24 308 2.4E-7 T 28-03-2018 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 159 170 1.1E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 104 114 1.1E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 61 72 1.1E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 296 313 1.1E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 Gene3D G3DSA:2.40.160.10 15 351 2.4E-60 T 28-03-2018 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 Pfam PF13609 Gram-negative porin 15 321 1.5E-48 T 28-03-2018 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 SUPERFAMILY SSF56935 26 351 1.28E-74 T 28-03-2018 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00184 Neisseria sp. porin signature 158 175 8.8E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00184 Neisseria sp. porin signature 63 88 8.8E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS21080 dbda527252ece87db0b862287e45db68 351 PRINTS PR00184 Neisseria sp. porin signature 293 317 8.8E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 2.6E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 2.6E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 2.6E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 2.6E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 2.6E-59 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.6E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 Gene3D G3DSA:1.20.120.30 26 187 3.3E-23 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 Gene3D G3DSA:1.10.287.1060 241 324 0.017 T 28-03-2018 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 186 5.2E-35 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 Gene3D G3DSA:1.10.287.950 325 517 2.3E-48 T 28-03-2018 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 Pfam PF00672 HAMP domain 213 259 9.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 SMART SM00283 266 513 9.4E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 SMART SM00304 213 265 8.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05870 7885fb104f9a64a0cde74e6806198976 582 SUPERFAMILY SSF58104 233 514 1.23E-76 T 28-03-2018 hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 Pfam PF03466 LysR substrate binding domain 89 293 2.5E-40 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 Gene3D G3DSA:3.40.190.10 90 175 2.7E-13 T 28-03-2018 hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 Gene3D G3DSA:1.10.10.10 1 89 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 SUPERFAMILY SSF53850 90 296 1.09E-42 T 28-03-2018 hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 Gene3D G3DSA:3.40.190.10 176 264 7.8E-23 T 28-03-2018 hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.9E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24045 76bcaec94b9f8230bc5c0c772e5d4171 301 SUPERFAMILY SSF46785 4 85 2.69E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 PRINTS PR00606 Class ID cytochrome C signature 79 89 1.8E-15 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 PRINTS PR00606 Class ID cytochrome C signature 91 101 1.8E-15 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 PRINTS PR00606 Class ID cytochrome C signature 64 77 1.8E-15 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 PRINTS PR00606 Class ID cytochrome C signature 41 54 1.8E-15 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 PRINTS PR00606 Class ID cytochrome C signature 26 39 1.8E-15 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 Pfam PF00034 Cytochrome c 29 102 1.4E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 Gene3D G3DSA:1.10.760.10 22 103 1.5E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS19620 92d5f386fa6640eeef1075fb62c2261f 105 SUPERFAMILY SSF46626 28 102 5.64E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 SUPERFAMILY SSF46626 220 328 7.19E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 Pfam PF00034 Cytochrome c 76 174 8.7E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 Pfam PF00034 Cytochrome c 224 328 3.0E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 Gene3D G3DSA:1.10.760.10 218 343 6.7E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 Gene3D G3DSA:1.10.760.10 345 481 2.1E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 PIRSF PIRSF000018 50 495 1.2E-155 T 28-03-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 Gene3D G3DSA:1.10.760.10 35 189 3.5E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 SUPERFAMILY SSF46626 64 174 4.46E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 365 452 1.7E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS10760 7256b3a7b921cb130cc6b8340abfa143 516 SUPERFAMILY SSF46626 367 484 3.56E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 SMART SM00382 289 484 1.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 SMART SM00382 30 230 2.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 SUPERFAMILY SSF52540 244 487 7.17E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 Gene3D G3DSA:3.40.50.300 262 510 3.7E-39 T 28-03-2018 hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 Gene3D G3DSA:3.40.50.300 2 255 4.2E-51 T 28-03-2018 hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 SUPERFAMILY SSF52540 4 232 1.7E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 TIGRFAM TIGR02633 xylG: D-xylose ABC transporter, ATP-binding protein 5 504 6.9E-272 T 28-03-2018 IPR013455 ABC transporter, D-xylose, ATP-binding protein GO:0005524|GO:0015614|GO:0015753|GO:0016020 hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 Pfam PF00005 ABC transporter 21 173 2.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16510 9fd9a3dd9d713560f59b52e3f4ac00dc 517 Pfam PF00005 ABC transporter 281 435 5.3E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS02355 47b796c92cecdc5592c7b521bf48b15c 402 Gene3D G3DSA:1.20.1250.20 197 400 1.1E-12 T 28-03-2018 hmeg3_RS02355 47b796c92cecdc5592c7b521bf48b15c 402 Gene3D G3DSA:1.20.1250.20 1 196 3.3E-17 T 28-03-2018 hmeg3_RS02355 47b796c92cecdc5592c7b521bf48b15c 402 SUPERFAMILY SSF103473 6 391 3.53E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS02355 47b796c92cecdc5592c7b521bf48b15c 402 Pfam PF07690 Major Facilitator Superfamily 27 345 2.9E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18245 c98ad588241d3a50a5fa7868a51d9828 70 Pfam PF05532 CsbD-like 4 55 9.7E-19 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS18245 c98ad588241d3a50a5fa7868a51d9828 70 SUPERFAMILY SSF69047 1 66 9.55E-26 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS18245 c98ad588241d3a50a5fa7868a51d9828 70 Gene3D G3DSA:1.10.1470.10 1 68 4.4E-22 T 28-03-2018 IPR008462 CsbD-like domain hmeg3_RS18245 c98ad588241d3a50a5fa7868a51d9828 70 PIRSF PIRSF039008 1 66 1.6E-30 T 28-03-2018 IPR026042 Stress response protein YjbJ hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 Gene3D G3DSA:3.40.640.10 14 262 5.1E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 Pfam PF00266 Aminotransferase class-V 2 353 5.8E-53 T 28-03-2018 IPR000192 Aminotransferase class V domain hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 SUPERFAMILY SSF53383 1 364 1.75E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 2 364 9.0E-157 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 PIRSF PIRSF000525 1 365 5.2E-152 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 Gene3D G3DSA:3.90.1150.10 263 363 5.2E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 364 49.623 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 hmeg3_RS17995 cefd090609e9d8d9c2076e15af769208 365 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site hmeg3_RS11595 aee53b76522fd3e9f56b288676d94256 204 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 6 183 2.7E-89 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO hmeg3_RS11595 aee53b76522fd3e9f56b288676d94256 204 SUPERFAMILY SSF46626 18 196 3.2E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11595 aee53b76522fd3e9f56b288676d94256 204 Gene3D G3DSA:1.10.760.10 36 204 6.9E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11595 aee53b76522fd3e9f56b288676d94256 204 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 5 180 1.4E-84 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO hmeg3_RS12160 d579f5f36ae008752a47e2faf9e0c882 260 Gene3D G3DSA:1.10.3720.10 10 219 8.3E-40 T 28-03-2018 hmeg3_RS12160 d579f5f36ae008752a47e2faf9e0c882 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 208 2.1E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12160 d579f5f36ae008752a47e2faf9e0c882 260 SUPERFAMILY SSF161098 14 202 1.57E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12160 d579f5f36ae008752a47e2faf9e0c882 260 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 8.1E-28 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS10615 731c284017a0ad850884bcf687aba4a9 103 SMART SM00749 41 103 0.008 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS10615 731c284017a0ad850884bcf687aba4a9 103 Pfam PF04972 BON domain 36 103 7.2E-18 T 28-03-2018 IPR007055 BON domain hmeg3_RS22340 0b90e0f75e60f82a5eb3f6f8cf938dd8 254 Gene3D G3DSA:3.90.226.10 2 210 8.7E-61 T 28-03-2018 hmeg3_RS22340 0b90e0f75e60f82a5eb3f6f8cf938dd8 254 Gene3D G3DSA:1.10.12.10 211 245 3.2E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS22340 0b90e0f75e60f82a5eb3f6f8cf938dd8 254 SUPERFAMILY SSF52096 3 252 3.98E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS22340 0b90e0f75e60f82a5eb3f6f8cf938dd8 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 251 1.1E-58 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS06045 550189cf063061a85dd572d641374c04 597 PIRSF PIRSF001294 1 595 6.7E-243 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 hmeg3_RS06045 550189cf063061a85dd572d641374c04 597 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 593 36.014 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 hmeg3_RS06045 550189cf063061a85dd572d641374c04 597 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 234 592 1.7E-161 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 hmeg3_RS06045 550189cf063061a85dd572d641374c04 597 Pfam PF03814 Potassium-transporting ATPase A subunit 10 591 6.3E-244 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 Gene3D G3DSA:2.60.40.1180 160 320 7.9E-18 T 28-03-2018 hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 Gene3D G3DSA:2.60.40.1180 37 132 1.5E-16 T 28-03-2018 hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 SUPERFAMILY SSF81901 37 255 1.57E-35 T 28-03-2018 hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 Pfam PF08238 Sel1 repeat 100 134 0.0021 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 Pfam PF08238 Sel1 repeat 207 241 4.4E-4 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 Pfam PF08238 Sel1 repeat 172 206 3.9E-6 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 Pfam PF08238 Sel1 repeat 65 96 1.5E-4 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 SMART SM00671 171 206 1.0E-6 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 SMART SM00671 207 242 1.9E-5 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 SMART SM00671 99 134 2.6E-5 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 SMART SM00671 63 98 1.4E-4 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS11765 f138289453fd36b4b5a46a596be27955 325 SMART SM00671 135 170 32.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS12885 be8a67d7c822835c570ef9050749cb25 349 Pfam PF00248 Aldo/keto reductase family 16 340 1.6E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS12885 be8a67d7c822835c570ef9050749cb25 349 PRINTS PR00069 Aldo-keto reductase signature 119 137 4.8E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS12885 be8a67d7c822835c570ef9050749cb25 349 PRINTS PR00069 Aldo-keto reductase signature 167 184 4.8E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS12885 be8a67d7c822835c570ef9050749cb25 349 SUPERFAMILY SSF51430 1 347 4.58E-107 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS12885 be8a67d7c822835c570ef9050749cb25 349 Gene3D G3DSA:3.20.20.100 1 349 3.7E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 392 437 1.0E-7 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 Pfam PF11734 TilS substrate C-terminal domain 392 455 5.8E-17 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 Pfam PF09179 TilS substrate binding domain 272 338 4.8E-16 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 Pfam PF01171 PP-loop family 39 224 5.1E-52 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 SMART SM00977 392 472 7.9E-14 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 Gene3D G3DSA:3.40.50.620 37 252 8.0E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 39 228 8.2E-51 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 SUPERFAMILY SSF82829 258 342 3.01E-22 T 28-03-2018 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 SUPERFAMILY SSF56037 351 453 2.3E-21 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 SUPERFAMILY SSF52402 39 253 1.39E-51 T 28-03-2018 hmeg3_RS09020 aaa263d2261c2c4c52c5c2cdc3d4786c 477 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 15 307 22.299 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 hmeg3_RS16475 8828b37b3a80c2a4fe16d276516b8a2a 236 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 78 233 4.0E-36 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16475 8828b37b3a80c2a4fe16d276516b8a2a 236 Pfam PF00990 Diguanylate cyclase, GGDEF domain 81 231 7.9E-33 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS16475 8828b37b3a80c2a4fe16d276516b8a2a 236 SUPERFAMILY SSF55073 86 233 1.18E-39 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS16475 8828b37b3a80c2a4fe16d276516b8a2a 236 Gene3D G3DSA:3.30.70.270 64 234 2.2E-48 T 28-03-2018 hmeg3_RS16475 8828b37b3a80c2a4fe16d276516b8a2a 236 SMART SM00267 70 235 1.7E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 Pfam PF00155 Aminotransferase class I and II 166 469 3.2E-28 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 SUPERFAMILY SSF46785 1 70 1.46E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 2.6E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 Gene3D G3DSA:3.40.640.10 145 393 4.9E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 SMART SM00345 7 66 8.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 Gene3D G3DSA:3.90.1150.10 394 492 1.8E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 SUPERFAMILY SSF53383 120 490 2.37E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS05415 6ecb2f99b224e4d9a112cbf7364a9acc 545 Gene3D G3DSA:1.10.10.10 1 68 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 SUPERFAMILY SSF50331 238 354 2.49E-13 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 Gene3D G3DSA:3.40.50.300 1 240 8.6E-73 T 28-03-2018 hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 SUPERFAMILY SSF52540 4 242 7.92E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 Gene3D G3DSA:2.40.50.100 241 295 1.1E-4 T 28-03-2018 hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 SMART SM00382 28 211 3.3E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 Pfam PF00005 ABC transporter 21 161 3.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24520 f8e9fc1420b67d9ba0b35dd360dd4720 364 Pfam PF08402 TOBE domain 278 348 5.1E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS15665 21c556d637cd09cf55f17e314392a648 283 Gene3D G3DSA:3.90.25.10 144 252 3.6E-4 T 28-03-2018 hmeg3_RS15665 21c556d637cd09cf55f17e314392a648 283 SUPERFAMILY SSF51735 2 244 4.16E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS15665 21c556d637cd09cf55f17e314392a648 283 Pfam PF05368 NmrA-like family 2 220 1.1E-21 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 hmeg3_RS15665 21c556d637cd09cf55f17e314392a648 283 Gene3D G3DSA:3.40.50.720 1 143 7.4E-19 T 28-03-2018 hmeg3_RS14075 be4afaf52b35d584a5796bce51da4fd1 307 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 303 1.5E-61 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 hmeg3_RS14075 be4afaf52b35d584a5796bce51da4fd1 307 Gene3D G3DSA:3.40.190.10 22 165 4.3E-27 T 28-03-2018 hmeg3_RS14075 be4afaf52b35d584a5796bce51da4fd1 307 SUPERFAMILY SSF53850 34 306 4.89E-64 T 28-03-2018 hmeg3_RS14075 be4afaf52b35d584a5796bce51da4fd1 307 Gene3D G3DSA:3.40.190.10 185 305 2.5E-18 T 28-03-2018 hmeg3_RS13640 d47469691fb0912f1d32178913c929c9 151 Pfam PF13527 Acetyltransferase (GNAT) domain 3 142 2.4E-11 T 28-03-2018 hmeg3_RS13640 d47469691fb0912f1d32178913c929c9 151 SUPERFAMILY SSF55729 1 146 9.97E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS13640 d47469691fb0912f1d32178913c929c9 151 Gene3D G3DSA:3.40.630.30 1 150 4.2E-24 T 28-03-2018 hmeg3_RS20735 72c7d898d3d7cb5805050a9e844676ae 156 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 105 4.6E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain hmeg3_RS20735 72c7d898d3d7cb5805050a9e844676ae 156 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 94 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 hmeg3_RS20735 72c7d898d3d7cb5805050a9e844676ae 156 SUPERFAMILY SSF53927 4 153 5.02E-34 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 hmeg3_RS20735 72c7d898d3d7cb5805050a9e844676ae 156 Gene3D G3DSA:3.40.140.10 2 156 1.1E-33 T 28-03-2018 hmeg3_RS20010 3f31e5ba1f556fc7128c164354475387 174 Gene3D G3DSA:1.20.950.20 1 174 3.3E-32 T 28-03-2018 hmeg3_RS20010 3f31e5ba1f556fc7128c164354475387 174 SUPERFAMILY SSF81342 2 174 2.28E-34 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 hmeg3_RS20010 3f31e5ba1f556fc7128c164354475387 174 Pfam PF01292 Prokaryotic cytochrome b561 3 173 1.3E-29 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 Gene3D G3DSA:1.10.10.10 1 90 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 SUPERFAMILY SSF46785 4 113 3.52E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 Gene3D G3DSA:3.40.190.10 94 179 2.4E-15 T 28-03-2018 hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 Pfam PF03466 LysR substrate binding domain 90 291 1.9E-35 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 Gene3D G3DSA:3.40.190.10 180 263 6.7E-15 T 28-03-2018 hmeg3_RS07290 1adfea4f3ff833a0244e152f84a9889e 305 SUPERFAMILY SSF53850 90 294 7.78E-38 T 28-03-2018 hmeg3_RS09250 b9262adc7cc96a0d7834961360e3a34f 265 SUPERFAMILY SSF51556 2 256 1.6E-69 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS09250 b9262adc7cc96a0d7834961360e3a34f 265 Gene3D G3DSA:3.20.20.140 1 261 4.0E-67 T 28-03-2018 hmeg3_RS09250 b9262adc7cc96a0d7834961360e3a34f 265 PIRSF PIRSF005902 1 261 6.7E-61 T 28-03-2018 IPR001130 TatD family GO:0016788 hmeg3_RS09250 b9262adc7cc96a0d7834961360e3a34f 265 Pfam PF01026 TatD related DNase 3 257 2.8E-60 T 28-03-2018 IPR001130 TatD family GO:0016788 hmeg3_RS09250 b9262adc7cc96a0d7834961360e3a34f 265 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 195 211 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 16 169 16.802 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 ProSitePatterns PS00855 Signal peptidases II signature. 112 124 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 62 70 3.3E-19 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 109 124 3.3E-19 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 145 161 3.3E-19 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 Pfam PF01252 Signal peptidase (SPase) II 25 164 5.3E-39 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS06660 6fd743a581b7ef46a3836e05c415b8cf 169 TIGRFAM TIGR00077 lspA: signal peptidase II 20 166 6.0E-41 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 hmeg3_RS08820 5d6b65a720659efd19095366fd66576d 245 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 245 36.921 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 hmeg3_RS08820 5d6b65a720659efd19095366fd66576d 245 Gene3D G3DSA:3.40.1210.10 1 245 8.9E-85 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 hmeg3_RS08820 5d6b65a720659efd19095366fd66576d 245 SUPERFAMILY SSF64167 1 244 5.62E-85 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 hmeg3_RS08820 5d6b65a720659efd19095366fd66576d 245 Pfam PF01975 Survival protein SurE 3 182 3.9E-58 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 hmeg3_RS08820 5d6b65a720659efd19095366fd66576d 245 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 6.4E-64 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 hmeg3_RS23470 2bbc9257d764e19bf65eea8ac9cd2183 235 Pfam PF02230 Phospholipase/Carboxylesterase 34 217 4.4E-14 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 hmeg3_RS23470 2bbc9257d764e19bf65eea8ac9cd2183 235 Gene3D G3DSA:3.40.50.1820 26 229 9.2E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS23470 2bbc9257d764e19bf65eea8ac9cd2183 235 SUPERFAMILY SSF53474 29 229 3.05E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS08325 3a2566708f7c96716103337e10ca0dbb 117 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 46 62 2.5E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 hmeg3_RS08325 3a2566708f7c96716103337e10ca0dbb 117 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 81 97 2.5E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 hmeg3_RS08325 3a2566708f7c96716103337e10ca0dbb 117 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 102 115 2.5E-17 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 hmeg3_RS08325 3a2566708f7c96716103337e10ca0dbb 117 Pfam PF02049 Flagellar hook-basal body complex protein FliE 36 117 1.8E-32 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 hmeg3_RS08325 3a2566708f7c96716103337e10ca0dbb 117 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 9 117 19.826 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 hmeg3_RS08325 3a2566708f7c96716103337e10ca0dbb 117 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 36 117 5.6E-27 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 hmeg3_RS07550 6d77596c1561068205199115220eb006 171 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 6 156 8.1E-48 T 28-03-2018 IPR026353 Hypoxanthine-DNA glycosylase hmeg3_RS07550 6d77596c1561068205199115220eb006 171 Gene3D G3DSA:3.40.470.10 2 167 1.1E-44 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS07550 6d77596c1561068205199115220eb006 171 SMART SM00986 8 160 5.7E-11 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS07550 6d77596c1561068205199115220eb006 171 SUPERFAMILY SSF52141 7 160 5.62E-37 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS07550 6d77596c1561068205199115220eb006 171 Pfam PF03167 Uracil DNA glycosylase superfamily 10 160 9.2E-15 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 hmeg3_RS07550 6d77596c1561068205199115220eb006 171 SMART SM00987 8 160 5.7E-11 T 28-03-2018 hmeg3_RS14235 29a39befdffddc551181be23f31bc61e 95 SUPERFAMILY SSF47661 18 72 8.89E-7 T 28-03-2018 IPR010989 SNARE GO:0016020|GO:0016192 hmeg3_RS14235 29a39befdffddc551181be23f31bc61e 95 Gene3D G3DSA:1.20.58.70 12 94 2.9E-6 T 28-03-2018 hmeg3_RS10660 0eca2ae573391121593cdf2b55734b50 132 Gene3D G3DSA:2.170.150.20 1 132 2.2E-61 T 28-03-2018 hmeg3_RS10660 0eca2ae573391121593cdf2b55734b50 132 Pfam PF01641 SelR domain 11 130 1.3E-54 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS10660 0eca2ae573391121593cdf2b55734b50 132 SUPERFAMILY SSF51316 5 131 4.66E-60 T 28-03-2018 IPR011057 Mss4-like hmeg3_RS10660 0eca2ae573391121593cdf2b55734b50 132 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 8 131 37.668 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS10660 0eca2ae573391121593cdf2b55734b50 132 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 130 3.7E-58 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS08460 aa043847e01385a20d6cff454a2de476 124 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 121 3.2E-35 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein hmeg3_RS08460 aa043847e01385a20d6cff454a2de476 124 Gene3D G3DSA:3.40.1230.10 1 62 6.1E-13 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein hmeg3_RS08460 aa043847e01385a20d6cff454a2de476 124 Gene3D G3DSA:3.40.1230.10 63 124 5.6E-23 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein hmeg3_RS08460 aa043847e01385a20d6cff454a2de476 124 SUPERFAMILY SSF64076 1 122 2.62E-37 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 Gene3D G3DSA:3.40.50.10800 123 216 1.5E-17 T 28-03-2018 hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 Gene3D G3DSA:3.40.50.10800 30 118 2.8E-17 T 28-03-2018 hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 35 347 1.2E-111 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 Hamap MF_00567 Quinolinate synthase A [nadA]. 2 353 66.209 T 28-03-2018 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 SUPERFAMILY SSF142754 37 347 4.18E-108 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 Gene3D G3DSA:3.40.50.10800 217 329 1.8E-33 T 28-03-2018 hmeg3_RS10145 e5076752c02a4c95576a85d77e1191d8 374 Pfam PF02445 Quinolinate synthetase A protein 40 346 2.1E-103 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 hmeg3_RS18985 755e063610718c324e358ecbc03b2eb5 332 Gene3D G3DSA:3.90.850.10 103 321 3.4E-20 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18985 755e063610718c324e358ecbc03b2eb5 332 SUPERFAMILY SSF56529 116 317 6.04E-20 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS18985 755e063610718c324e358ecbc03b2eb5 332 PIRSF PIRSF033905 1 332 7.3E-151 T 28-03-2018 IPR009645 Uncharacterised conserved protein GguC hmeg3_RS08650 9acb25fcd325c46280fe765ed8437c78 185 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 10 115 1.2E-44 T 28-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 hmeg3_RS08650 9acb25fcd325c46280fe765ed8437c78 185 Pfam PF05233 PHB accumulation regulatory domain 126 165 2.8E-17 T 28-03-2018 IPR007897 PHB accumulation regulatory hmeg3_RS08650 9acb25fcd325c46280fe765ed8437c78 185 Pfam PF05233 PHB accumulation regulatory domain 75 113 1.1E-17 T 28-03-2018 IPR007897 PHB accumulation regulatory hmeg3_RS08650 9acb25fcd325c46280fe765ed8437c78 185 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 11 70 1.0E-30 T 28-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal hmeg3_RS17980 47181c6117730101c992825d8b8c4aa6 298 Pfam PF02153 Prephenate dehydrogenase 16 271 1.1E-69 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 hmeg3_RS17980 47181c6117730101c992825d8b8c4aa6 298 SUPERFAMILY SSF51735 3 170 5.51E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS17980 47181c6117730101c992825d8b8c4aa6 298 Gene3D G3DSA:3.40.50.720 1 172 6.8E-35 T 28-03-2018 hmeg3_RS17980 47181c6117730101c992825d8b8c4aa6 298 Gene3D G3DSA:1.10.3660.10 182 295 2.6E-28 T 28-03-2018 hmeg3_RS17980 47181c6117730101c992825d8b8c4aa6 298 SUPERFAMILY SSF48179 174 282 6.69E-33 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS00055 7b18a52d887737b4ed7be10b1244d863 257 Gene3D G3DSA:3.40.50.300 5 256 3.6E-76 T 28-03-2018 hmeg3_RS00055 7b18a52d887737b4ed7be10b1244d863 257 SUPERFAMILY SSF52540 9 251 8.23E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00055 7b18a52d887737b4ed7be10b1244d863 257 SMART SM00382 34 229 4.8E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00055 7b18a52d887737b4ed7be10b1244d863 257 PIRSF PIRSF039085 6 256 8.0E-115 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS00055 7b18a52d887737b4ed7be10b1244d863 257 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS00055 7b18a52d887737b4ed7be10b1244d863 257 Pfam PF00005 ABC transporter 25 181 4.7E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS13340 87594943a4b015246b31ade61632c11b 225 SUPERFAMILY SSF161098 4 214 2.22E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS13340 87594943a4b015246b31ade61632c11b 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 23 211 1.8E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS13340 87594943a4b015246b31ade61632c11b 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 9 210 5.5E-72 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 hmeg3_RS13340 87594943a4b015246b31ade61632c11b 225 Gene3D G3DSA:1.10.3720.10 1 223 9.8E-40 T 28-03-2018 hmeg3_RS11625 1fd3b7f919aaedde011c43450b8348cb 77 Gene3D G3DSA:1.10.260.40 33 69 4.8E-5 T 28-03-2018 hmeg3_RS11625 1fd3b7f919aaedde011c43450b8348cb 77 Gene3D G3DSA:1.10.10.60 7 32 8.8E-8 T 28-03-2018 hmeg3_RS11625 1fd3b7f919aaedde011c43450b8348cb 77 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 41 2.0E-5 T 28-03-2018 hmeg3_RS20520 99621bc5116d8e78b1b861220d048996 278 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 264 2.1E-47 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 hmeg3_RS20520 99621bc5116d8e78b1b861220d048996 278 PIRSF PIRSF006157 1 266 5.2E-86 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 hmeg3_RS20520 99621bc5116d8e78b1b861220d048996 278 Gene3D G3DSA:3.40.830.10 1 265 2.0E-88 T 28-03-2018 hmeg3_RS20520 99621bc5116d8e78b1b861220d048996 278 SUPERFAMILY SSF53213 5 265 3.53E-90 T 28-03-2018 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 SUPERFAMILY SSF46785 6 111 1.36E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.8E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 SUPERFAMILY SSF53850 89 292 9.46E-35 T 28-03-2018 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 Gene3D G3DSA:3.40.190.10 89 176 3.3E-14 T 28-03-2018 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 Gene3D G3DSA:1.10.10.10 2 84 3.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 Gene3D G3DSA:3.40.190.10 177 268 6.7E-16 T 28-03-2018 hmeg3_RS23905 41a78b27831839c427c67940ae6ab5cb 301 Pfam PF03466 LysR substrate binding domain 88 291 4.8E-32 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04165 fe89283e96d3d528be7d6fa3745e699c 140 Gene3D G3DSA:1.10.10.10 4 140 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04165 fe89283e96d3d528be7d6fa3745e699c 140 SUPERFAMILY SSF46785 7 138 2.03E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04165 fe89283e96d3d528be7d6fa3745e699c 140 SMART SM00347 28 126 8.7E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS04165 fe89283e96d3d528be7d6fa3745e699c 140 Pfam PF01047 MarR family 36 92 4.0E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS01310 bd6f2a762fcec5b833b4fe1ded13fee8 157 SUPERFAMILY SSF54427 3 157 1.63E-45 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS01310 bd6f2a762fcec5b833b4fe1ded13fee8 157 Pfam PF13577 SnoaL-like domain 9 141 3.2E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS01310 bd6f2a762fcec5b833b4fe1ded13fee8 157 Gene3D G3DSA:3.10.450.50 1 153 1.1E-26 T 28-03-2018 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 SMART SM00382 40 223 4.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 Gene3D G3DSA:3.40.50.300 11 258 2.0E-70 T 28-03-2018 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 46 341 1.1E-109 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 Gene3D G3DSA:2.40.50.100 311 370 0.16 T 28-03-2018 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 Pfam PF00005 ABC transporter 31 173 5.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 SUPERFAMILY SSF50331 248 369 2.04E-16 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 SUPERFAMILY SSF52540 15 252 2.59E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 Gene3D G3DSA:2.40.50.100 259 310 1.5E-4 T 28-03-2018 hmeg3_RS12010 8e12027159d8ee850684dd8e875f97e6 370 Pfam PF08402 TOBE domain 291 369 3.8E-12 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS18095 beeb51b55f300868e9a38f2a974af145 233 Pfam PF01618 MotA/TolQ/ExbB proton channel family 86 218 1.5E-41 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 hmeg3_RS18095 beeb51b55f300868e9a38f2a974af145 233 TIGRFAM TIGR02796 tolQ: protein TolQ 8 230 5.5E-85 T 28-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 hmeg3_RS03750 45eba0dd0a6b43051f4b040e4bd49aba 308 SUPERFAMILY SSF52283 42 116 2.66E-5 T 28-03-2018 hmeg3_RS03750 45eba0dd0a6b43051f4b040e4bd49aba 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 273 4.8E-46 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS03750 45eba0dd0a6b43051f4b040e4bd49aba 308 Gene3D G3DSA:3.40.50.720 13 118 4.2E-11 T 28-03-2018 hmeg3_RS03750 45eba0dd0a6b43051f4b040e4bd49aba 308 SUPERFAMILY SSF51735 95 274 2.76E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS03750 45eba0dd0a6b43051f4b040e4bd49aba 308 Gene3D G3DSA:3.40.50.720 119 274 2.7E-36 T 28-03-2018 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 SUPERFAMILY SSF55205 13 436 5.23E-130 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 PIRSF PIRSF000505 8 441 5.9E-146 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 ProSitePatterns PS00885 EPSP synthase signature 2. 347 365 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 Gene3D G3DSA:3.65.10.10 235 439 1.3E-66 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 20 438 5.4E-140 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 Gene3D G3DSA:3.65.10.10 27 234 5.4E-60 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 ProSitePatterns PS00104 EPSP synthase signature 1. 95 109 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 16 440 33.912 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 hmeg3_RS17975 4b29bf4e8e4385e0e8731a1347b74294 443 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 14 433 2.4E-136 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 hmeg3_RS20745 dcd94639fcbac942a0317422fd076585 154 Pfam PF06445 GyrI-like small molecule binding domain 1 154 3.2E-30 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain hmeg3_RS20745 dcd94639fcbac942a0317422fd076585 154 Gene3D G3DSA:3.20.80.10 1 154 6.9E-31 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain hmeg3_RS20745 dcd94639fcbac942a0317422fd076585 154 SMART SM00871 1 154 1.1E-27 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding hmeg3_RS20745 dcd94639fcbac942a0317422fd076585 154 SUPERFAMILY SSF55136 1 154 1.74E-35 T 28-03-2018 hmeg3_RS19335 beb98b370fb5de094fc3fdf41cc3b047 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 280 1.5E-34 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19335 beb98b370fb5de094fc3fdf41cc3b047 293 Gene3D G3DSA:1.10.3470.10 5 284 5.9E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 SUPERFAMILY SSF56024 289 460 1.32E-45 T 28-03-2018 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 65 466 1.8E-95 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 SUPERFAMILY SSF56024 93 306 5.83E-44 T 28-03-2018 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 Pfam PF13091 PLD-like domain 317 443 9.4E-29 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 Pfam PF13091 PLD-like domain 119 230 1.2E-11 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 SMART SM00155 202 229 7.9E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 SMART SM00155 389 416 3.3E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 Gene3D G3DSA:3.30.870.10 294 462 4.3E-33 T 28-03-2018 hmeg3_RS18580 f5bd0f289f157882160c5f1a7cb19caf 476 Gene3D G3DSA:3.30.870.10 92 293 2.7E-33 T 28-03-2018 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 Pfam PF01019 Gamma-glutamyltranspeptidase 25 524 4.8E-125 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 SUPERFAMILY SSF56235 8 528 1.33E-142 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 251 270 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 222 238 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 398 413 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 32 57 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 344 362 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS06025 22853b8b1a0cb9d29f9825c99956e155 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 368 386 6.7E-23 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24150 22f95e6a4412325f67eb423a8e5a5cf4 133 SUPERFAMILY SSF55331 1 113 4.67E-10 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily hmeg3_RS24150 22f95e6a4412325f67eb423a8e5a5cf4 133 Gene3D G3DSA:3.30.429.10 2 111 6.0E-17 T 28-03-2018 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 351 1.4E-130 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 SMART SM01329 2 351 1.3E-200 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 Gene3D G3DSA:3.40.718.10 1 356 2.5E-122 T 28-03-2018 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 350 7.3E-147 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 SUPERFAMILY SSF53659 2 355 1.31E-119 T 28-03-2018 hmeg3_RS17240 38ddb19c29ad8b35d8a35b1ec98b45a0 356 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 355 50.117 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 ProSitePatterns PS00057 Ribosomal protein S18 signature. 39 62 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 Gene3D G3DSA:4.10.640.10 6 94 5.6E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 Pfam PF01084 Ribosomal protein S18 37 86 2.2E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 TIGRFAM TIGR00165 S18: ribosomal protein bS18 23 90 1.3E-33 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 SUPERFAMILY SSF46911 18 90 4.58E-27 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 PRINTS PR00974 Ribosomal protein S18 family signature 78 88 1.4E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 PRINTS PR00974 Ribosomal protein S18 family signature 46 56 1.4E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 PRINTS PR00974 Ribosomal protein S18 family signature 64 78 1.4E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 PRINTS PR00974 Ribosomal protein S18 family signature 56 63 1.4E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 39 90 9.0E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS08390 150a2be47abcdb49decf7927b5b2c87e 94 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 20 91 19.992 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS23090 e3e039258a0177000a8c4df08afd14d7 278 SUPERFAMILY SSF103481 38 132 4.05E-12 T 28-03-2018 hmeg3_RS23090 e3e039258a0177000a8c4df08afd14d7 278 SUPERFAMILY SSF103481 179 276 1.96E-15 T 28-03-2018 hmeg3_RS23090 e3e039258a0177000a8c4df08afd14d7 278 Pfam PF00892 EamA-like transporter family 6 129 1.4E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS23090 e3e039258a0177000a8c4df08afd14d7 278 Pfam PF00892 EamA-like transporter family 140 274 1.8E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS03085 5e8ef426b4464579cb288e83b0bb7853 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 214 5.6E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03085 5e8ef426b4464579cb288e83b0bb7853 223 Gene3D G3DSA:1.10.3720.10 2 222 1.2E-34 T 28-03-2018 hmeg3_RS03085 5e8ef426b4464579cb288e83b0bb7853 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 111 9.0E-30 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS03085 5e8ef426b4464579cb288e83b0bb7853 223 SUPERFAMILY SSF161098 16 202 7.59E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS07560 20de9ce4e9c5c808cd0ab2ab4cbd03ba 147 Pfam PF06127 Protein of unknown function (DUF962) 13 142 2.5E-20 T 28-03-2018 IPR009305 Protein of unknown function DUF962 hmeg3_RS02810 6af37ef7f1f0244cb2ab4f8ed1a08ae0 252 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 234 4.6E-31 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 hmeg3_RS02810 6af37ef7f1f0244cb2ab4f8ed1a08ae0 252 Gene3D G3DSA:3.30.420.40 88 252 5.1E-48 T 28-03-2018 hmeg3_RS02810 6af37ef7f1f0244cb2ab4f8ed1a08ae0 252 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 252 18.284 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 hmeg3_RS02810 6af37ef7f1f0244cb2ab4f8ed1a08ae0 252 SUPERFAMILY SSF53067 1 121 1.62E-22 T 28-03-2018 hmeg3_RS02810 6af37ef7f1f0244cb2ab4f8ed1a08ae0 252 Pfam PF03309 Type III pantothenate kinase 2 206 1.5E-54 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 hmeg3_RS02810 6af37ef7f1f0244cb2ab4f8ed1a08ae0 252 SUPERFAMILY SSF53067 124 250 1.72E-27 T 28-03-2018 hmeg3_RS04610 b59e2053adc5a96bbdacd777e7060295 212 Pfam PF01810 LysE type translocator 16 206 3.4E-23 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS11635 b116b90875b15e5a919e65957e37ec24 75 Pfam PF03621 MbtH-like protein 2 50 9.0E-24 T 28-03-2018 IPR005153 MbtH-like protein hmeg3_RS11635 b116b90875b15e5a919e65957e37ec24 75 Gene3D G3DSA:3.90.820.10 1 66 5.0E-33 T 28-03-2018 hmeg3_RS11635 b116b90875b15e5a919e65957e37ec24 75 SUPERFAMILY SSF160582 2 68 1.57E-28 T 28-03-2018 hmeg3_RS11635 b116b90875b15e5a919e65957e37ec24 75 SMART SM00923 1 51 1.4E-26 T 28-03-2018 IPR005153 MbtH-like protein hmeg3_RS04195 08a9975ba12f6718b37b062d0726cd59 429 SUPERFAMILY SSF103473 11 399 3.66E-18 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04195 08a9975ba12f6718b37b062d0726cd59 429 Gene3D G3DSA:1.20.1250.20 6 208 2.5E-5 T 28-03-2018 hmeg3_RS04195 08a9975ba12f6718b37b062d0726cd59 429 Pfam PF13347 MFS/sugar transport protein 11 414 8.5E-51 T 28-03-2018 hmeg3_RS04195 08a9975ba12f6718b37b062d0726cd59 429 Gene3D G3DSA:1.20.1250.20 215 427 2.0E-13 T 28-03-2018 hmeg3_RS10840 7ed2b5280d42ee137b5527cbaed80999 269 Pfam PF00149 Calcineurin-like phosphoesterase 3 190 8.2E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS10840 7ed2b5280d42ee137b5527cbaed80999 269 SUPERFAMILY SSF56300 1 242 7.34E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS10840 7ed2b5280d42ee137b5527cbaed80999 269 Gene3D G3DSA:3.60.21.10 2 246 9.6E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 SUPERFAMILY SSF46689 238 285 1.02E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 SMART SM00342 201 283 2.2E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 Pfam PF12833 Helix-turn-helix domain 208 281 1.0E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 Pfam PF06719 AraC-type transcriptional regulator N-terminus 25 172 7.2E-33 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 Gene3D G3DSA:1.10.10.60 242 290 3.0E-11 T 28-03-2018 hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 SUPERFAMILY SSF46689 186 234 3.1E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS16975 a3e010f2660d1af92e184604205cbf8b 298 Gene3D G3DSA:1.10.10.60 173 241 3.0E-14 T 28-03-2018 hmeg3_RS08335 1618a9104c85649769166f3e306f0c5d 95 SUPERFAMILY SSF160544 7 86 1.83E-23 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal hmeg3_RS08335 1618a9104c85649769166f3e306f0c5d 95 Gene3D G3DSA:3.40.1690.10 9 85 9.7E-30 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal hmeg3_RS08335 1618a9104c85649769166f3e306f0c5d 95 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 82 3.8E-19 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 Gene3D G3DSA:1.10.10.10 127 209 4.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 SMART SM00421 145 202 2.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 SUPERFAMILY SSF52172 1 129 3.56E-32 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 Pfam PF00072 Response regulator receiver domain 4 116 1.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 Gene3D G3DSA:3.40.50.2300 1 126 7.4E-35 T 28-03-2018 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 3.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 SMART SM00448 2 115 2.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18230 3d320646def43fc1828dd9f93410cd9d 209 SUPERFAMILY SSF46894 138 208 3.27E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS01375 61e032506eae502827258e1d5b373563 110 Gene3D G3DSA:3.30.2310.20 27 110 3.1E-11 T 28-03-2018 hmeg3_RS01375 61e032506eae502827258e1d5b373563 110 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 33 110 8.6E-8 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 hmeg3_RS01375 61e032506eae502827258e1d5b373563 110 SUPERFAMILY SSF143011 27 109 3.01E-11 T 28-03-2018 IPR035095 Toxin RelE-like domain hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 SUPERFAMILY SSF58104 245 518 1.07E-70 T 28-03-2018 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 Gene3D G3DSA:1.20.120.30 24 186 2.2E-17 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 Gene3D G3DSA:1.10.287.1060 245 327 0.29 T 28-03-2018 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 SMART SM00283 268 515 2.8E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 289 318 4.0E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 443 472 4.0E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 424 4.0E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 366 393 4.0E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 4.0E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 185 1.1E-27 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 483 8.8E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01605 efb1cce284194c50d97800af35691010 571 Gene3D G3DSA:1.10.287.950 328 519 1.1E-47 T 28-03-2018 hmeg3_RS13330 766470a66c889cad954a375cbb248bf9 119 SUPERFAMILY SSF46785 7 110 1.86E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13330 766470a66c889cad954a375cbb248bf9 119 Gene3D G3DSA:1.10.10.10 2 107 8.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13330 766470a66c889cad954a375cbb248bf9 119 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 83 4.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS08770 db38024359fff0b6355399b5809a31ae 89 Pfam PF03937 Flavinator of succinate dehydrogenase 12 76 8.2E-23 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase hmeg3_RS08770 db38024359fff0b6355399b5809a31ae 89 Gene3D G3DSA:1.10.150.250 6 89 1.8E-24 T 28-03-2018 hmeg3_RS08770 db38024359fff0b6355399b5809a31ae 89 SUPERFAMILY SSF109910 5 83 5.89E-21 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase hmeg3_RS20860 b17fbe197ede993dc24b87999f856a7c 239 SUPERFAMILY SSF53335 16 237 2.33E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS20860 b17fbe197ede993dc24b87999f856a7c 239 Pfam PF02390 Putative methyltransferase 63 233 5.8E-54 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 hmeg3_RS20860 b17fbe197ede993dc24b87999f856a7c 239 Gene3D G3DSA:3.40.50.150 29 239 2.5E-23 T 28-03-2018 hmeg3_RS20860 b17fbe197ede993dc24b87999f856a7c 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 23 238 28.428 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 hmeg3_RS20860 b17fbe197ede993dc24b87999f856a7c 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 49 237 7.3E-52 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 Pfam PF01965 DJ-1/PfpI family 22 193 1.2E-28 T 28-03-2018 IPR002818 DJ-1/PfpI hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 Gene3D G3DSA:1.10.10.60 248 284 8.3E-9 T 28-03-2018 hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 Gene3D G3DSA:3.40.50.880 19 247 1.3E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 SUPERFAMILY SSF46689 234 282 1.25E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 SUPERFAMILY SSF46689 286 336 1.57E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 Gene3D G3DSA:1.10.10.60 285 337 1.6E-8 T 28-03-2018 hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 SUPERFAMILY SSF52317 20 214 1.39E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 SMART SM00342 249 332 5.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS24145 d03cb6780e5cb4f048a3cd36e91d2920 339 Pfam PF12833 Helix-turn-helix domain 255 333 9.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS11455 95b0c11b2470314fe4d69e0fac09565a 140 Gene3D G3DSA:1.20.120.50 1 124 4.8E-26 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 hmeg3_RS11455 95b0c11b2470314fe4d69e0fac09565a 140 SUPERFAMILY SSF47188 1 123 2.35E-25 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 hmeg3_RS11455 95b0c11b2470314fe4d69e0fac09565a 140 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 123 1.1E-21 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 hmeg3_RS14785 ff0ce997caaaec63804a68cdec110e15 414 Gene3D G3DSA:1.20.1600.10 20 414 7.6E-45 T 28-03-2018 hmeg3_RS14785 ff0ce997caaaec63804a68cdec110e15 414 Pfam PF02321 Outer membrane efflux protein 238 409 2.6E-16 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS14785 ff0ce997caaaec63804a68cdec110e15 414 Pfam PF02321 Outer membrane efflux protein 29 213 1.0E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS14785 ff0ce997caaaec63804a68cdec110e15 414 SUPERFAMILY SSF56954 3 413 2.22E-53 T 28-03-2018 hmeg3_RS24000 bebe8c8795b23448d5a0cf2046ec0c9a 172 Pfam PF01863 Protein of unknown function DUF45 93 154 1.5E-8 T 28-03-2018 IPR002725 Protein of unknown function DUF45 hmeg3_RS08570 ff289f1947638ffef9cf0e6f3bcc1db2 238 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 227 5.3E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS08570 ff289f1947638ffef9cf0e6f3bcc1db2 238 SUPERFAMILY SSF52096 4 228 5.6E-49 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS08570 ff289f1947638ffef9cf0e6f3bcc1db2 238 Gene3D G3DSA:3.90.226.10 1 232 2.1E-50 T 28-03-2018 hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 Gene3D G3DSA:1.10.1670.10 261 304 2.1E-10 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 Gene3D G3DSA:3.30.310.20 14 116 4.4E-28 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 SMART SM01009 14 131 8.8E-41 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 SUPERFAMILY SSF48150 121 298 7.15E-40 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 SMART SM00478 141 306 3.6E-9 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 137 265 1.2E-6 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 SUPERFAMILY SSF55945 16 112 8.79E-22 T 28-03-2018 hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 Pfam PF06029 AlkA N-terminal domain 16 131 9.3E-29 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal hmeg3_RS18055 0653b03caab116bae4d921f6a50474a5 310 Gene3D G3DSA:1.10.340.30 117 260 2.0E-31 T 28-03-2018 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 PRINTS PR00050 Cold shock protein signature 43 61 2.3E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 PRINTS PR00050 Cold shock protein signature 7 22 2.3E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 PRINTS PR00050 Cold shock protein signature 28 37 2.3E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 SMART SM00357 6 70 4.0E-25 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 2.0E-27 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 Gene3D G3DSA:2.40.50.140 1 70 3.4E-26 T 28-03-2018 hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 SUPERFAMILY SSF50249 3 69 2.14E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS00345 63ee10d6eab5bb19b411b7fa226b79ce 70 PIRSF PIRSF002599 1 70 3.3E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 hmeg3_RS15475 461c1d86e0a1cf716ff29de217e1669f 154 SMART SM00450 27 137 5.0E-9 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS15475 461c1d86e0a1cf716ff29de217e1669f 154 Gene3D G3DSA:3.40.250.10 3 154 2.1E-19 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS15475 461c1d86e0a1cf716ff29de217e1669f 154 Pfam PF00581 Rhodanese-like domain 27 130 6.9E-6 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS15475 461c1d86e0a1cf716ff29de217e1669f 154 SUPERFAMILY SSF52821 23 151 3.01E-18 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS16920 fdd38267813945bbc16dcaec7460a990 311 SUPERFAMILY SSF53474 50 309 1.05E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS16920 fdd38267813945bbc16dcaec7460a990 311 Gene3D G3DSA:3.40.50.1820 16 311 2.3E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS16920 fdd38267813945bbc16dcaec7460a990 311 Pfam PF01738 Dienelactone hydrolase family 72 308 1.4E-16 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 Gene3D G3DSA:3.40.50.2300 203 379 2.5E-21 T 28-03-2018 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 SUPERFAMILY SSF53822 31 410 1.18E-89 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 Pfam PF13433 Periplasmic binding protein domain 32 408 8.9E-171 T 28-03-2018 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 32 405 1.1E-177 T 28-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 95 105 2.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 2.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 291 304 2.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 2.3E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS00330 77affc6a30d90e465b1fee00bdc08be4 417 Gene3D G3DSA:3.40.50.2300 28 202 5.4E-27 T 28-03-2018 hmeg3_RS10120 33ccc97c18e5f04df5260b83d410f725 148 SUPERFAMILY SSF55620 1 147 6.67E-38 T 28-03-2018 hmeg3_RS10120 33ccc97c18e5f04df5260b83d410f725 148 Gene3D G3DSA:3.30.479.10 1 148 2.9E-37 T 28-03-2018 hmeg3_RS10120 33ccc97c18e5f04df5260b83d410f725 148 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 117 1.1E-28 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 hmeg3_RS10120 33ccc97c18e5f04df5260b83d410f725 148 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 146 1.5E-34 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 hmeg3_RS16640 aae0db787860cc59899c5d11d7598f1c 196 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 187 1.6E-53 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 hmeg3_RS16640 aae0db787860cc59899c5d11d7598f1c 196 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 3.2E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 hmeg3_RS16640 aae0db787860cc59899c5d11d7598f1c 196 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 hmeg3_RS16640 aae0db787860cc59899c5d11d7598f1c 196 PIRSF PIRSF000847 1 194 8.4E-45 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 hmeg3_RS13810 566ff3c138e30720cd86edbf6c060533 184 Pfam PF13463 Winged helix DNA-binding domain 66 131 1.3E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS13810 566ff3c138e30720cd86edbf6c060533 184 PIRSF PIRSF036158 2 184 4.6E-65 T 28-03-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain hmeg3_RS13810 566ff3c138e30720cd86edbf6c060533 184 SUPERFAMILY SSF46785 37 149 3.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13810 566ff3c138e30720cd86edbf6c060533 184 Gene3D G3DSA:1.10.10.10 55 150 7.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 Pfam PF00072 Response regulator receiver domain 4 113 7.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 SMART SM00862 145 218 1.2E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 SMART SM00448 1 112 6.3E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 Gene3D G3DSA:1.10.10.10 122 224 2.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 SUPERFAMILY SSF52172 1 166 6.69E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 Gene3D G3DSA:3.40.50.2300 1 121 1.9E-36 T 28-03-2018 hmeg3_RS07075 ec09d46e313793c31f35dbf6aea82032 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 3.8E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SMART SM00028 853 886 0.43 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SMART SM00028 736 769 98.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 Gene3D G3DSA:1.10.260.40 54 122 3.5E-8 T 28-03-2018 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SUPERFAMILY SSF48452 1048 1077 1.61E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SUPERFAMILY SSF48452 850 1010 1.61E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 Gene3D G3DSA:1.25.40.10 840 1122 1.7E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SUPERFAMILY SSF47413 55 118 2.81E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 Pfam PF13191 AAA ATPase domain 312 504 6.0E-14 T 28-03-2018 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 Gene3D G3DSA:1.25.40.10 665 839 4.7E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SMART SM00530 56 115 0.0031 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 Gene3D G3DSA:3.40.50.300 313 607 2.0E-5 T 28-03-2018 hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SUPERFAMILY SSF52540 434 544 5.62E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SUPERFAMILY SSF52540 301 378 5.62E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS23615 2ad63864c4707ee3f1e01bc58813b1e2 1140 SUPERFAMILY SSF48452 736 888 3.11E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 Pfam PF00355 Rieske [2Fe-2S] domain 59 181 1.4E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 SUPERFAMILY SSF50022 32 197 1.81E-40 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 11 195 4.0E-62 T 28-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 Gene3D G3DSA:2.102.10.10 34 202 3.7E-45 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 PRINTS PR00162 Rieske 2Fe-2S subunit signature 122 133 3.9E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 PRINTS PR00162 Rieske 2Fe-2S subunit signature 154 166 3.9E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 hmeg3_RS03565 03f61ed6c05ee04de10df62edd6eb656 202 Gene3D G3DSA:1.20.5.510 5 33 2.1E-9 T 28-03-2018 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 Pfam PF16200 C-terminal region of band_7 243 303 1.1E-24 T 28-03-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 Pfam PF01145 SPFH domain / Band 7 family 23 192 7.6E-33 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 SUPERFAMILY SSF117892 50 184 3.01E-40 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 PRINTS PR00721 Stomatin signature 109 126 3.0E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 PRINTS PR00721 Stomatin signature 74 95 3.0E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 PRINTS PR00721 Stomatin signature 172 193 3.0E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 PRINTS PR00721 Stomatin signature 129 152 3.0E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 PRINTS PR00721 Stomatin signature 153 171 3.0E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 PRINTS PR00721 Stomatin signature 26 48 3.0E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 hmeg3_RS10035 bfe933784315b2aaf581d6ce7d2bab01 304 SMART SM00244 19 177 3.7E-59 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS03860 6a576b70931d0ea9db113f756b8f1b7e 508 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 430 2.9E-79 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS03860 6a576b70931d0ea9db113f756b8f1b7e 508 Gene3D G3DSA:3.90.76.10 39 181 1.3E-29 T 28-03-2018 hmeg3_RS03860 6a576b70931d0ea9db113f756b8f1b7e 508 SUPERFAMILY SSF53850 27 507 1.45E-107 T 28-03-2018 hmeg3_RS03860 6a576b70931d0ea9db113f756b8f1b7e 508 Gene3D G3DSA:3.40.190.10 182 295 3.2E-33 T 28-03-2018 hmeg3_RS03860 6a576b70931d0ea9db113f756b8f1b7e 508 Gene3D G3DSA:3.10.105.10 296 480 1.2E-30 T 28-03-2018 hmeg3_RS03860 6a576b70931d0ea9db113f756b8f1b7e 508 PIRSF PIRSF002741 4 507 6.9E-81 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS19330 e6b996de224c3e3766d301ff9a0b23e4 347 Gene3D G3DSA:1.10.3470.10 11 324 6.7E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS19330 e6b996de224c3e3766d301ff9a0b23e4 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 312 1.5E-30 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14440 3bc45f368bc073f7e935fcce9dae1c31 204 Pfam PF06821 Serine hydrolase 27 187 1.8E-51 T 28-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 hmeg3_RS14440 3bc45f368bc073f7e935fcce9dae1c31 204 Gene3D G3DSA:3.40.50.1820 11 197 1.7E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS14440 3bc45f368bc073f7e935fcce9dae1c31 204 SUPERFAMILY SSF53474 26 184 9.59E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 SUPERFAMILY SSF81901 11 186 8.72E-9 T 28-03-2018 hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 SUPERFAMILY SSF81901 254 391 7.72E-16 T 28-03-2018 hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 SMART SM00671 315 350 0.11 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 SMART SM00671 351 387 23.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 SMART SM00671 18 54 5.9E-7 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 SMART SM00671 270 314 86.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Pfam PF08238 Sel1 repeat 18 53 3.1E-5 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Pfam PF08238 Sel1 repeat 165 177 64.0 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Pfam PF08238 Sel1 repeat 282 313 0.19 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Pfam PF08238 Sel1 repeat 364 383 0.014 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Pfam PF08238 Sel1 repeat 333 350 0.89 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Gene3D G3DSA:2.60.40.1180 362 400 0.15 T 28-03-2018 hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Gene3D G3DSA:2.60.40.1180 340 361 0.21 T 28-03-2018 hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Gene3D G3DSA:2.60.40.1180 3 64 6.9E-9 T 28-03-2018 hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Gene3D G3DSA:2.60.40.1180 251 339 1.3E-6 T 28-03-2018 hmeg3_RS02855 672895d4957eee667ba7ec581f6b0099 532 Gene3D G3DSA:2.60.40.1180 103 190 0.066 T 28-03-2018 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 Gene3D G3DSA:3.30.930.10 11 463 2.0E-98 T 28-03-2018 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 SUPERFAMILY SSF55826 218 393 1.96E-36 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 559 7.8E-224 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 462 2.0E-44 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 Pfam PF04073 Aminoacyl-tRNA editing domain 257 382 1.6E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 PIRSF PIRSF001535 1 574 7.5E-267 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 Gene3D G3DSA:3.40.50.800 464 574 1.6E-30 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 SUPERFAMILY SSF55681 10 237 5.9E-102 T 28-03-2018 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 SUPERFAMILY SSF55681 410 480 5.9E-102 T 28-03-2018 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.8E-18 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.8E-18 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.8E-18 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.8E-18 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 SUPERFAMILY SSF52954 466 573 9.16E-31 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 Pfam PF03129 Anticodon binding domain 479 570 5.2E-17 T 28-03-2018 IPR004154 Anticodon-binding hmeg3_RS21855 7af8aa0efec7c9e8acbf3aa3fe9387b7 574 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 574 40.71 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 hmeg3_RS05760 3dd51432afd244e53bb85d73be8202ad 396 SUPERFAMILY SSF56112 26 353 2.19E-35 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS05760 3dd51432afd244e53bb85d73be8202ad 396 Pfam PF01636 Phosphotransferase enzyme family 65 298 1.7E-14 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase hmeg3_RS05760 3dd51432afd244e53bb85d73be8202ad 396 Gene3D G3DSA:3.90.1200.10 137 393 1.1E-13 T 28-03-2018 hmeg3_RS05760 3dd51432afd244e53bb85d73be8202ad 396 Gene3D G3DSA:3.30.200.20 32 126 1.1E-6 T 28-03-2018 hmeg3_RS21290 43ff2f624eb533688ae59731b055a26f 500 SUPERFAMILY SSF55729 352 487 1.52E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS21290 43ff2f624eb533688ae59731b055a26f 500 Pfam PF13302 Acetyltransferase (GNAT) domain 356 485 4.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS21290 43ff2f624eb533688ae59731b055a26f 500 Gene3D G3DSA:3.40.630.30 339 493 1.1E-17 T 28-03-2018 hmeg3_RS21290 43ff2f624eb533688ae59731b055a26f 500 SUPERFAMILY SSF53756 129 349 1.06E-10 T 28-03-2018 hmeg3_RS21290 43ff2f624eb533688ae59731b055a26f 500 Gene3D G3DSA:3.40.50.2000 168 337 2.9E-14 T 28-03-2018 hmeg3_RS21290 43ff2f624eb533688ae59731b055a26f 500 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 1 292 7.6E-84 T 28-03-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase hmeg3_RS12735 d2b4f43e37a2bf29d39f2a4f893a1103 297 Gene3D G3DSA:3.40.50.720 1 171 1.6E-20 T 28-03-2018 hmeg3_RS12735 d2b4f43e37a2bf29d39f2a4f893a1103 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 6.4E-16 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS12735 d2b4f43e37a2bf29d39f2a4f893a1103 297 SUPERFAMILY SSF51735 1 285 1.35E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12735 d2b4f43e37a2bf29d39f2a4f893a1103 297 Gene3D G3DSA:3.90.25.10 172 292 2.0E-13 T 28-03-2018 hmeg3_RS12640 4976efc78fa959ee601d858ca474e5d7 207 Gene3D G3DSA:3.90.550.10 11 204 9.0E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS12640 4976efc78fa959ee601d858ca474e5d7 207 SUPERFAMILY SSF53448 15 200 1.71E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS12640 4976efc78fa959ee601d858ca474e5d7 207 Pfam PF12804 MobA-like NTP transferase domain 17 177 7.6E-31 T 28-03-2018 IPR025877 MobA-like NTP transferase hmeg3_RS06730 c2d25c818cb84b3713630d281037db35 231 Gene3D G3DSA:3.40.50.850 16 231 8.7E-52 T 28-03-2018 hmeg3_RS06730 c2d25c818cb84b3713630d281037db35 231 Pfam PF00857 Isochorismatase family 24 215 1.7E-42 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS06730 c2d25c818cb84b3713630d281037db35 231 SUPERFAMILY SSF52499 7 228 2.09E-55 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 Gene3D G3DSA:1.10.287.950 316 516 1.9E-47 T 28-03-2018 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 Pfam PF02203 Tar ligand binding domain homologue 1 172 2.2E-40 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 Pfam PF00672 HAMP domain 212 260 7.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 SUPERFAMILY SSF47170 46 146 1.03E-6 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 SMART SM00283 265 512 9.5E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 SUPERFAMILY SSF58104 232 517 2.09E-71 T 28-03-2018 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 Gene3D G3DSA:1.20.120.30 23 186 7.8E-26 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 2.4E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 SMART SM00304 212 264 4.9E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 8.8E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 8.8E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 8.8E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 8.8E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 15 40 8.8E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS16345 50d31d89e3bd8edcc0405847fccc7f50 546 Gene3D G3DSA:1.10.287.950 211 315 9.0E-11 T 28-03-2018 hmeg3_RS23450 8d8aba7757c1da03227ffda8f91670ba 652 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 556 645 3.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23450 8d8aba7757c1da03227ffda8f91670ba 652 Gene3D G3DSA:3.30.565.10 415 646 3.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23450 8d8aba7757c1da03227ffda8f91670ba 652 SMART SM00387 551 647 3.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS23450 8d8aba7757c1da03227ffda8f91670ba 652 SUPERFAMILY SSF55874 505 646 7.73E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 Pfam PF03466 LysR substrate binding domain 88 292 1.5E-44 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.5E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 Gene3D G3DSA:3.40.190.10 90 177 4.3E-15 T 28-03-2018 hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 SUPERFAMILY SSF53850 89 293 1.21E-48 T 28-03-2018 hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 Gene3D G3DSA:1.10.10.10 2 89 4.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 Gene3D G3DSA:3.40.190.10 178 263 3.7E-25 T 28-03-2018 hmeg3_RS13285 36dea7c8d4279e99472c715ff202469c 333 SUPERFAMILY SSF46785 2 86 1.27E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 SUPERFAMILY SSF46785 2 108 4.32E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 Gene3D G3DSA:3.40.190.10 177 249 2.7E-15 T 28-03-2018 hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 SUPERFAMILY SSF53850 85 285 2.61E-36 T 28-03-2018 hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 Gene3D G3DSA:3.40.190.10 79 176 3.0E-22 T 28-03-2018 hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 Gene3D G3DSA:1.10.10.10 1 78 5.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 Pfam PF03466 LysR substrate binding domain 85 285 7.7E-41 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS04255 02c91a28859ebdbe743cdb83d7c64c49 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20130 6fd6fdce053df42b887c9e9cbcc516aa 175 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 21 169 1.7E-60 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 hmeg3_RS20130 6fd6fdce053df42b887c9e9cbcc516aa 175 Pfam PF01967 MoaC family 32 167 6.1E-54 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 hmeg3_RS20130 6fd6fdce053df42b887c9e9cbcc516aa 175 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 19 175 36.092 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 hmeg3_RS20130 6fd6fdce053df42b887c9e9cbcc516aa 175 Gene3D G3DSA:3.30.70.640 19 175 3.0E-69 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 hmeg3_RS20130 6fd6fdce053df42b887c9e9cbcc516aa 175 SUPERFAMILY SSF55040 28 172 3.79E-60 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 Pfam PF03477 ATP cone domain 163 244 4.8E-6 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 Pfam PF03477 ATP cone domain 43 138 1.5E-17 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 689 712 1.0E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 623 646 1.0E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 586 597 1.0E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 451 470 1.0E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 661 683 1.0E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 765 792 1.0E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 302 913 1.2E-209 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 Gene3D G3DSA:3.20.70.20 281 917 2.8E-207 T 28-03-2018 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 SUPERFAMILY SSF48168 162 374 1.96E-63 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 Pfam PF02867 Ribonucleotide reductase, barrel domain 376 910 8.4E-178 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 299 370 1.4E-20 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 754 776 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 SUPERFAMILY SSF51998 845 913 2.23E-175 T 28-03-2018 hmeg3_RS21800 0dd870fb9e057a0b873b4280364da7c6 991 SUPERFAMILY SSF51998 375 814 2.23E-175 T 28-03-2018 hmeg3_RS17280 d3ccfe38320fa9cbd07bc895722655aa 149 SUPERFAMILY SSF54631 2 126 5.18E-27 T 28-03-2018 hmeg3_RS17280 d3ccfe38320fa9cbd07bc895722655aa 149 Pfam PF00571 CBS domain 75 125 1.8E-8 T 28-03-2018 IPR000644 CBS domain hmeg3_RS17280 d3ccfe38320fa9cbd07bc895722655aa 149 Pfam PF00571 CBS domain 15 60 1.9E-9 T 28-03-2018 IPR000644 CBS domain hmeg3_RS17280 d3ccfe38320fa9cbd07bc895722655aa 149 SMART SM00116 13 60 1.8E-8 T 28-03-2018 IPR000644 CBS domain hmeg3_RS17280 d3ccfe38320fa9cbd07bc895722655aa 149 SMART SM00116 78 125 5.4E-5 T 28-03-2018 IPR000644 CBS domain hmeg3_RS17280 d3ccfe38320fa9cbd07bc895722655aa 149 Gene3D G3DSA:3.10.580.10 1 147 4.7E-25 T 28-03-2018 hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 SUPERFAMILY SSF161098 46 286 8.97E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 43 579 1.2E-236 T 28-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 Gene3D G3DSA:1.10.3720.10 315 576 5.2E-27 T 28-03-2018 hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 Gene3D G3DSA:1.10.3720.10 40 299 3.0E-35 T 28-03-2018 hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 295 3.2E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 388 564 6.5E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10720 ca01e5c6cb3ce531b8b16d3dae5583fa 584 SUPERFAMILY SSF161098 312 565 3.55E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS07010 d9a09db46f0f2c2392dba5bff2ab79af 130 SUPERFAMILY SSF102546 1 130 5.36E-41 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 hmeg3_RS07010 d9a09db46f0f2c2392dba5bff2ab79af 130 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 130 31.261 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 hmeg3_RS07010 d9a09db46f0f2c2392dba5bff2ab79af 130 Gene3D G3DSA:3.40.1650.10 1 130 2.1E-33 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 hmeg3_RS07010 d9a09db46f0f2c2392dba5bff2ab79af 130 Pfam PF05025 RbsD / FucU transport protein family 1 129 1.3E-43 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 hmeg3_RS14275 a52c051cd3a6a53833c1fd4fbc6ddc09 266 SUPERFAMILY SSF53850 27 266 3.76E-84 T 28-03-2018 hmeg3_RS14275 a52c051cd3a6a53833c1fd4fbc6ddc09 266 Gene3D G3DSA:3.40.190.10 27 120 1.4E-21 T 28-03-2018 hmeg3_RS14275 a52c051cd3a6a53833c1fd4fbc6ddc09 266 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 10 264 1.2E-81 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS14275 a52c051cd3a6a53833c1fd4fbc6ddc09 266 Pfam PF03180 NLPA lipoprotein 28 266 9.0E-91 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS14275 a52c051cd3a6a53833c1fd4fbc6ddc09 266 Gene3D G3DSA:3.40.190.10 121 266 1.5E-53 T 28-03-2018 hmeg3_RS14275 a52c051cd3a6a53833c1fd4fbc6ddc09 266 PIRSF PIRSF002854 1 266 1.7E-101 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS20140 a804b49b1bff9954c92c2efe2646d144 241 Pfam PF03741 Integral membrane protein TerC family 14 188 8.6E-43 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 hmeg3_RS20140 a804b49b1bff9954c92c2efe2646d144 241 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 189 2.0E-66 T 28-03-2018 IPR022301 Integral membrane protein YjbE hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 SMART SM00448 1 111 3.2E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 SUPERFAMILY SSF52172 2 176 2.7E-42 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 Pfam PF00072 Response regulator receiver domain 3 111 2.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 Gene3D G3DSA:1.10.10.10 123 223 1.2E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 5.4E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 Gene3D G3DSA:3.40.50.2300 1 122 7.3E-35 T 28-03-2018 hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 6.2E-104 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 hmeg3_RS14995 309d7443c63e52a68911864e3d952923 223 SMART SM00862 144 219 7.7E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06745 897c16f3484a8a1a456f9b66e1ce7cb6 365 Gene3D G3DSA:3.40.50.2300 290 365 1.2E-12 T 28-03-2018 hmeg3_RS06745 897c16f3484a8a1a456f9b66e1ce7cb6 365 Gene3D G3DSA:3.40.50.2300 151 289 5.4E-35 T 28-03-2018 hmeg3_RS06745 897c16f3484a8a1a456f9b66e1ce7cb6 365 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 31 316 1.5E-41 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 hmeg3_RS06745 897c16f3484a8a1a456f9b66e1ce7cb6 365 Gene3D G3DSA:3.40.50.2300 28 150 4.2E-25 T 28-03-2018 hmeg3_RS12045 aa2a0f70fcc382156d07c93c533d66d4 214 Pfam PF03352 Methyladenine glycosylase 22 198 1.1E-66 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 hmeg3_RS12045 aa2a0f70fcc382156d07c93c533d66d4 214 SUPERFAMILY SSF48150 21 201 8.63E-67 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 hmeg3_RS12045 aa2a0f70fcc382156d07c93c533d66d4 214 Gene3D G3DSA:1.10.340.30 19 199 1.1E-69 T 28-03-2018 hmeg3_RS20965 5446e55549b79b3f9fc7700688cc0d10 366 Pfam PF09084 NMT1/THI5 like 68 264 2.3E-29 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS20965 5446e55549b79b3f9fc7700688cc0d10 366 Gene3D G3DSA:3.40.190.10 61 148 1.5E-9 T 28-03-2018 hmeg3_RS20965 5446e55549b79b3f9fc7700688cc0d10 366 SUPERFAMILY SSF53850 55 271 2.46E-36 T 28-03-2018 hmeg3_RS20965 5446e55549b79b3f9fc7700688cc0d10 366 Gene3D G3DSA:3.40.190.10 149 352 3.9E-25 T 28-03-2018 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 173 193 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 473 495 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 262 277 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 227 245 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 88 109 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 335 355 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 426 449 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 2 23 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR00701 60kDa inner membrane protein signature 509 532 5.2E-77 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR01900 YidC translocation/secretion protein signature 498 522 2.6E-25 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR01900 YidC translocation/secretion protein signature 479 494 2.6E-25 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 PRINTS PR01900 YidC translocation/secretion protein signature 350 366 2.6E-25 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 Pfam PF02096 60Kd inner membrane protein 365 543 9.2E-62 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 364 543 1.3E-71 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 363 3.0E-113 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 Pfam PF14849 YidC periplasmic domain 82 354 2.1E-86 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal hmeg3_RS02595 d813167a48513cb9f90fac4dbf73a13e 550 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 545 24.987 T 28-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 hmeg3_RS02185 9917b0d94d1479f426ccafead1f6f112 429 Pfam PF02321 Outer membrane efflux protein 49 222 2.8E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS02185 9917b0d94d1479f426ccafead1f6f112 429 Pfam PF02321 Outer membrane efflux protein 255 422 2.1E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS02185 9917b0d94d1479f426ccafead1f6f112 429 Gene3D G3DSA:1.20.1600.10 33 428 2.0E-65 T 28-03-2018 hmeg3_RS02185 9917b0d94d1479f426ccafead1f6f112 429 SUPERFAMILY SSF56954 2 422 3.01E-79 T 28-03-2018 hmeg3_RS23575 448464602804dc56354a626643292b4f 287 Pfam PF05368 NmrA-like family 3 223 6.5E-15 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 hmeg3_RS23575 448464602804dc56354a626643292b4f 287 SUPERFAMILY SSF51735 3 236 1.32E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23575 448464602804dc56354a626643292b4f 287 Gene3D G3DSA:3.40.50.720 2 266 1.2E-18 T 28-03-2018 hmeg3_RS05810 8cc748a40c20db56a56c9e211f0d6872 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 215 3.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS05810 8cc748a40c20db56a56c9e211f0d6872 217 Gene3D G3DSA:1.10.3720.10 1 217 2.7E-39 T 28-03-2018 hmeg3_RS05810 8cc748a40c20db56a56c9e211f0d6872 217 SUPERFAMILY SSF161098 8 201 2.49E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19935 e8fc44ca1486954c5cba43b74148e9c9 215 SUPERFAMILY SSF53271 10 213 3.15E-62 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS19935 e8fc44ca1486954c5cba43b74148e9c9 215 Gene3D G3DSA:3.40.50.2020 8 213 6.2E-60 T 28-03-2018 hmeg3_RS19935 e8fc44ca1486954c5cba43b74148e9c9 215 Pfam PF14681 Uracil phosphoribosyltransferase 13 214 1.1E-70 T 28-03-2018 hmeg3_RS19935 e8fc44ca1486954c5cba43b74148e9c9 215 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 9 215 43.268 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 hmeg3_RS19935 e8fc44ca1486954c5cba43b74148e9c9 215 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 12 215 7.3E-77 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 hmeg3_RS20370 d47a7ffd34a6ecab875151e307ad6df9 277 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 16 277 1.4E-99 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 hmeg3_RS20370 d47a7ffd34a6ecab875151e307ad6df9 277 Pfam PF02548 Ketopantoate hydroxymethyltransferase 18 272 3.7E-110 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 hmeg3_RS20370 d47a7ffd34a6ecab875151e307ad6df9 277 Gene3D G3DSA:3.20.20.60 6 277 3.3E-83 T 28-03-2018 hmeg3_RS20370 d47a7ffd34a6ecab875151e307ad6df9 277 PIRSF PIRSF000388 9 277 4.2E-103 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 hmeg3_RS20370 d47a7ffd34a6ecab875151e307ad6df9 277 SUPERFAMILY SSF51621 18 277 3.57E-105 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS20370 d47a7ffd34a6ecab875151e307ad6df9 277 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 18 277 42.064 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 SUPERFAMILY SSF53822 34 372 7.33E-93 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 Gene3D G3DSA:3.40.50.2300 216 363 1.1E-20 T 28-03-2018 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 Gene3D G3DSA:3.40.50.2300 27 215 2.5E-41 T 28-03-2018 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 Pfam PF13458 Periplasmic binding protein 35 371 1.8E-58 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 36 52 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 98 108 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 77 95 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 288 301 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 58 74 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 340 355 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14265 71f55d043241b8816805d4f3000999be 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 265 283 5.0E-40 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS14720 8b70d28178b045b5447e6a28747abdd3 425 SUPERFAMILY SSF56349 181 398 1.22E-14 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS14720 8b70d28178b045b5447e6a28747abdd3 425 SUPERFAMILY SSF56349 103 150 1.22E-14 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS14720 8b70d28178b045b5447e6a28747abdd3 425 Pfam PF00589 Phage integrase family 197 363 8.0E-7 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS14720 8b70d28178b045b5447e6a28747abdd3 425 Gene3D G3DSA:1.10.150.130 49 148 8.6E-5 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS14720 8b70d28178b045b5447e6a28747abdd3 425 Gene3D G3DSA:1.10.443.10 190 413 9.6E-19 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 SUPERFAMILY SSF52317 253 444 1.6E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 18 443 6.5E-89 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 SUPERFAMILY SSF52540 15 200 5.53E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 Gene3D G3DSA:3.40.50.880 210 429 2.0E-23 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 13 437 36.77 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 17 194 1.6E-10 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 Gene3D G3DSA:3.40.50.300 6 209 6.8E-28 T 28-03-2018 hmeg3_RS12385 28f6f8ad552d193e59b9cb9e7fd56058 461 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 255 436 5.1E-34 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 3 193 1.1E-66 T 28-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 Gene3D G3DSA:3.30.70.1530 21 72 6.2E-17 T 28-03-2018 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 Pfam PF01514 Secretory protein of YscJ/FliF family 4 189 1.2E-14 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 164 176 9.2E-14 T 28-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 23 33 9.2E-14 T 28-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 75 88 9.2E-14 T 28-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 115 128 9.2E-14 T 28-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 hmeg3_RS15730 4b4515d1464306dc2d27640987f6a7fb 258 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 95 110 9.2E-14 T 28-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 hmeg3_RS12770 57b901f6f230e2ac7f82ffdd02b00ce9 300 Gene3D G3DSA:3.30.2350.10 91 297 3.9E-47 T 28-03-2018 hmeg3_RS12770 57b901f6f230e2ac7f82ffdd02b00ce9 300 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS12770 57b901f6f230e2ac7f82ffdd02b00ce9 300 SUPERFAMILY SSF55120 85 295 3.84E-51 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS12770 57b901f6f230e2ac7f82ffdd02b00ce9 300 Pfam PF00849 RNA pseudouridylate synthase 100 247 2.3E-26 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS22170 8b5b5d5afd69304293d4abeac955b6c8 167 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 1.4E-63 T 28-03-2018 IPR018531 Domain of unknown function DUF1993 hmeg3_RS22170 8b5b5d5afd69304293d4abeac955b6c8 167 SUPERFAMILY SSF109854 4 166 1.88E-61 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes hmeg3_RS22170 8b5b5d5afd69304293d4abeac955b6c8 167 Gene3D G3DSA:1.20.120.450 2 167 4.0E-69 T 28-03-2018 hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 SUPERFAMILY SSF47240 5 156 6.16E-42 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 PIRSF PIRSF005900 1 160 3.6E-43 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 Pfam PF00210 Ferritin-like domain 22 154 2.9E-22 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 40 56 2.7E-7 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 136 154 2.7E-7 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 64 80 2.7E-7 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 hmeg3_RS05360 9d5da7471f3a2176a758efef893522b4 161 Gene3D G3DSA:1.20.1260.10 5 157 5.4E-37 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS16130 69732cea6d342ff26aec2f78df987b88 159 PIRSF PIRSF000216 3 159 7.8E-47 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS16130 69732cea6d342ff26aec2f78df987b88 159 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 14 154 2.2E-43 T 28-03-2018 hmeg3_RS16130 69732cea6d342ff26aec2f78df987b88 159 Gene3D G3DSA:3.40.30.10 74 158 5.1E-14 T 28-03-2018 hmeg3_RS16130 69732cea6d342ff26aec2f78df987b88 159 SUPERFAMILY SSF52833 11 156 4.47E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS16130 69732cea6d342ff26aec2f78df987b88 159 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 113 131 - T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Gene3D G3DSA:2.60.40.10 343 460 1.2E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 29 458 1.6E-156 T 28-03-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Gene3D G3DSA:3.30.70.20 278 337 0.0075 T 28-03-2018 hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 SUPERFAMILY SSF54862 93 115 7.67E-32 T 28-03-2018 hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 SUPERFAMILY SSF54862 161 352 7.67E-32 T 28-03-2018 hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Pfam PF12801 4Fe-4S binding domain 83 125 6.6E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Gene3D G3DSA:3.30.70.20 259 277 0.016 T 28-03-2018 hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 343 460 1.2E-29 T 28-03-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Pfam PF13746 4Fe-4S dicluster domain 207 307 2.9E-38 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 255 266 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS11610 0c50dad0980424daeffb1b6b2f7aa545 461 Gene3D G3DSA:3.30.70.20 210 258 7.9E-11 T 28-03-2018 hmeg3_RS05520 0781dffb2df733f427ec01bf4ec2bcdc 364 SUPERFAMILY SSF55874 219 355 1.44E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05520 0781dffb2df733f427ec01bf4ec2bcdc 364 Gene3D G3DSA:3.30.565.10 157 356 3.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05520 0781dffb2df733f427ec01bf4ec2bcdc 364 Pfam PF06580 Histidine kinase 162 240 3.6E-21 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 hmeg3_RS17795 0086b8b2bfee5214f44647687a49a8e2 587 Gene3D G3DSA:1.20.91.10 237 312 5.4E-6 T 28-03-2018 hmeg3_RS17795 0086b8b2bfee5214f44647687a49a8e2 587 Pfam PF00999 Sodium/hydrogen exchanger family 13 378 2.3E-63 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 hmeg3_RS15375 fe86d399b52043b074a71e7c186a39c9 249 Pfam PF06629 MltA-interacting protein MipA 36 248 3.5E-36 T 28-03-2018 IPR010583 MltA-interacting MipA hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 45 523 41.552 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 Gene3D G3DSA:3.40.50.10490 1 142 9.2E-46 T 28-03-2018 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 Pfam PF00342 Phosphoglucose isomerase 51 540 4.2E-218 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 Gene3D G3DSA:1.10.1390.10 512 547 1.7E-18 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 SUPERFAMILY SSF53697 6 545 5.0E-217 T 28-03-2018 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 Gene3D G3DSA:3.40.50.10490 143 257 6.0E-51 T 28-03-2018 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 496 513 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 264 277 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 Gene3D G3DSA:3.40.50.10490 258 511 2.8E-120 T 28-03-2018 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 149 168 5.1E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 260 278 5.1E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 464 482 5.1E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 496 509 5.1E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 337 358 5.1E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS17855 039cf9bff490c94dcb8445f5feae210f 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 482 496 5.1E-54 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 Pfam PF00700 Bacterial flagellin C-terminal helical region 277 361 2.7E-26 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 Gene3D G3DSA:1.20.1330.10 40 334 6.2E-66 T 28-03-2018 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.2E-43 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 PRINTS PR00207 Flagellin signature 37 54 4.2E-23 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 PRINTS PR00207 Flagellin signature 111 134 4.2E-23 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 PRINTS PR00207 Flagellin signature 76 95 4.2E-23 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 hmeg3_RS08365 d6ba7d15340baec4540bf9ed95232f4e 362 SUPERFAMILY SSF64518 1 362 4.18E-91 T 28-03-2018 hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 SUPERFAMILY SSF48008 71 201 4.45E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 3.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 3.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 Pfam PF07729 FCD domain 76 198 4.3E-25 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 Gene3D G3DSA:1.20.120.530 63 214 4.4E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 SUPERFAMILY SSF46785 4 70 6.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 Gene3D G3DSA:1.10.10.10 1 62 8.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 SMART SM00345 8 66 1.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 SMART SM00895 76 200 3.0E-18 T 28-03-2018 IPR011711 GntR, C-terminal hmeg3_RS07980 d3ff30e37383d603441e48428885556f 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 63 1.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS08005 6ef6b18db7c9b486cfa59fd7844e95d4 184 SUPERFAMILY SSF54593 8 153 2.42E-38 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS08005 6ef6b18db7c9b486cfa59fd7844e95d4 184 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 135 2.1E-23 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS08005 6ef6b18db7c9b486cfa59fd7844e95d4 184 Gene3D G3DSA:3.10.180.10 3 163 3.7E-38 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS19300 9cc7cf059b5607794d411fa7cdf65159 265 Gene3D G3DSA:3.40.190.10 159 258 2.0E-7 T 28-03-2018 hmeg3_RS19300 9cc7cf059b5607794d411fa7cdf65159 265 SUPERFAMILY SSF53850 13 257 1.09E-47 T 28-03-2018 hmeg3_RS19300 9cc7cf059b5607794d411fa7cdf65159 265 Gene3D G3DSA:3.40.190.10 3 158 6.0E-28 T 28-03-2018 hmeg3_RS19300 9cc7cf059b5607794d411fa7cdf65159 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 257 2.3E-43 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS19300 9cc7cf059b5607794d411fa7cdf65159 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 62 75 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS19300 9cc7cf059b5607794d411fa7cdf65159 265 SMART SM00062 39 259 1.5E-31 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS21065 5186fa1ac853ecac9e8cd4870c16a871 112 SUPERFAMILY SSF54909 1 109 8.58E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS21065 5186fa1ac853ecac9e8cd4870c16a871 112 Pfam PF05336 L-rhamnose mutarotase 2 109 3.6E-29 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 hmeg3_RS06235 7f3d4af9d0ae4a38b72d25d144012f4d 252 SUPERFAMILY SSF53474 30 247 1.72E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06235 7f3d4af9d0ae4a38b72d25d144012f4d 252 Pfam PF12697 Alpha/beta hydrolase family 31 241 1.3E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS06235 7f3d4af9d0ae4a38b72d25d144012f4d 252 Gene3D G3DSA:3.40.50.1820 20 251 1.6E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02265 df9706222f17bf4be106641ce84f9f6a 274 SUPERFAMILY SSF52540 76 240 9.6E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02265 df9706222f17bf4be106641ce84f9f6a 274 Gene3D G3DSA:3.40.50.300 51 243 3.3E-14 T 28-03-2018 hmeg3_RS02265 df9706222f17bf4be106641ce84f9f6a 274 PIRSF PIRSF003073 12 263 2.0E-76 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein hmeg3_RS02265 df9706222f17bf4be106641ce84f9f6a 274 Pfam PF01695 IstB-like ATP binding protein 65 240 1.1E-58 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 hmeg3_RS02265 df9706222f17bf4be106641ce84f9f6a 274 SMART SM00382 109 244 1.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS02625 5321ed05caaa356c2a9e158724491597 206 SUPERFAMILY SSF48498 84 192 3.26E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS02625 5321ed05caaa356c2a9e158724491597 206 Gene3D G3DSA:1.10.10.60 1 61 8.3E-17 T 28-03-2018 hmeg3_RS02625 5321ed05caaa356c2a9e158724491597 206 Gene3D G3DSA:1.10.357.10 62 193 1.0E-15 T 28-03-2018 hmeg3_RS02625 5321ed05caaa356c2a9e158724491597 206 SUPERFAMILY SSF46689 3 73 5.13E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS02625 5321ed05caaa356c2a9e158724491597 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS11430 bfcbec3d4f1b63cdf2f0c980d83ec971 336 Pfam PF13411 MerR HTH family regulatory protein 15 79 7.5E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11430 bfcbec3d4f1b63cdf2f0c980d83ec971 336 SMART SM00422 15 81 1.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS11430 bfcbec3d4f1b63cdf2f0c980d83ec971 336 Gene3D G3DSA:1.10.1660.10 16 311 1.4E-20 T 28-03-2018 hmeg3_RS11430 bfcbec3d4f1b63cdf2f0c980d83ec971 336 SUPERFAMILY SSF46955 15 80 3.2E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS00890 4ec5b4e491832b675cd5b1bc97016606 324 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 135 3.2E-4 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS00890 4ec5b4e491832b675cd5b1bc97016606 324 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 176 277 1.7E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS00890 4ec5b4e491832b675cd5b1bc97016606 324 Gene3D G3DSA:2.30.110.10 163 301 1.1E-15 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS00890 4ec5b4e491832b675cd5b1bc97016606 324 SUPERFAMILY SSF50475 176 280 6.54E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS00890 4ec5b4e491832b675cd5b1bc97016606 324 Gene3D G3DSA:2.30.110.10 41 143 4.1E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 Pfam PF01019 Gamma-glutamyltranspeptidase 72 579 2.8E-192 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 SUPERFAMILY SSF56235 48 587 8.3E-201 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 299 318 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 153 171 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 423 441 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 399 417 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 464 479 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 171 190 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 269 285 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 79 104 3.3E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 57 578 1.1E-203 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS05090 4ebdced5ae41ca096b6467908ff09547 587 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 399 423 - T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS08355 24a2c218bcd7fc0ce284ae222ce73e6f 691 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 433 672 1.0E-49 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 hmeg3_RS08355 24a2c218bcd7fc0ce284ae222ce73e6f 691 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 15 90 1.5E-10 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 hmeg3_RS08355 24a2c218bcd7fc0ce284ae222ce73e6f 691 Pfam PF07196 Flagellin hook IN motif 351 401 1.6E-9 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 hmeg3_RS08355 24a2c218bcd7fc0ce284ae222ce73e6f 691 Pfam PF07196 Flagellin hook IN motif 126 179 2.5E-9 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 hmeg3_RS08355 24a2c218bcd7fc0ce284ae222ce73e6f 691 Pfam PF07196 Flagellin hook IN motif 256 307 3.6E-5 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 hmeg3_RS19130 a40f3013e33007cbd43132712a88b888 339 Pfam PF13416 Bacterial extracellular solute-binding protein 42 299 1.0E-30 T 28-03-2018 hmeg3_RS19130 a40f3013e33007cbd43132712a88b888 339 Gene3D G3DSA:3.40.190.10 13 139 1.4E-13 T 28-03-2018 hmeg3_RS19130 a40f3013e33007cbd43132712a88b888 339 SUPERFAMILY SSF53850 23 335 8.36E-60 T 28-03-2018 hmeg3_RS19130 a40f3013e33007cbd43132712a88b888 339 Gene3D G3DSA:3.40.190.10 140 294 6.1E-29 T 28-03-2018 hmeg3_RS11645 272051afa0c4a3f61b3b6ef64b3dc18b 320 Gene3D G3DSA:3.60.130.10 3 315 3.9E-71 T 28-03-2018 hmeg3_RS11645 272051afa0c4a3f61b3b6ef64b3dc18b 320 SUPERFAMILY SSF51197 13 313 1.37E-83 T 28-03-2018 hmeg3_RS11645 272051afa0c4a3f61b3b6ef64b3dc18b 320 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 28 312 4.5E-50 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS06645 f14f02ff4491b2da3284db0be171df03 363 SMART SM00228 92 184 3.4E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06645 f14f02ff4491b2da3284db0be171df03 363 Gene3D G3DSA:3.30.2010.10 169 258 1.2E-5 T 28-03-2018 hmeg3_RS06645 f14f02ff4491b2da3284db0be171df03 363 SUPERFAMILY SSF50156 118 194 9.2E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS06645 f14f02ff4491b2da3284db0be171df03 363 Gene3D G3DSA:2.30.42.10 80 168 2.5E-8 T 28-03-2018 hmeg3_RS23960 aa65aeaa26e9746d20bb72c4cbccf841 300 SUPERFAMILY SSF51197 52 285 1.0E-43 T 28-03-2018 hmeg3_RS23960 aa65aeaa26e9746d20bb72c4cbccf841 300 SMART SM00558 149 294 2.1E-7 T 28-03-2018 IPR003347 JmjC domain hmeg3_RS23960 aa65aeaa26e9746d20bb72c4cbccf841 300 Gene3D G3DSA:2.60.120.650 64 286 5.9E-40 T 28-03-2018 hmeg3_RS23960 aa65aeaa26e9746d20bb72c4cbccf841 300 Pfam PF13621 Cupin-like domain 78 283 2.0E-30 T 28-03-2018 hmeg3_RS10675 ba974756bdd76135ef73936e3788cc09 592 SUPERFAMILY SSF56024 168 316 5.49E-8 T 28-03-2018 hmeg3_RS10675 ba974756bdd76135ef73936e3788cc09 592 Gene3D G3DSA:3.30.870.10 151 351 1.6E-7 T 28-03-2018 hmeg3_RS10675 ba974756bdd76135ef73936e3788cc09 592 Gene3D G3DSA:3.30.870.10 367 574 4.3E-8 T 28-03-2018 hmeg3_RS10675 ba974756bdd76135ef73936e3788cc09 592 SUPERFAMILY SSF56024 371 544 4.54E-9 T 28-03-2018 hmeg3_RS10675 ba974756bdd76135ef73936e3788cc09 592 Pfam PF13091 PLD-like domain 200 313 2.8E-8 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 hmeg3_RS20175 1d2a081c71ed5b989cbf38fe93ae25df 201 PRINTS PR00344 Bacterial sensor protein C-terminal signature 159 177 4.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20175 1d2a081c71ed5b989cbf38fe93ae25df 201 PRINTS PR00344 Bacterial sensor protein C-terminal signature 141 155 4.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20175 1d2a081c71ed5b989cbf38fe93ae25df 201 PRINTS PR00344 Bacterial sensor protein C-terminal signature 188 201 4.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS20175 1d2a081c71ed5b989cbf38fe93ae25df 201 SMART SM00387 106 201 0.0029 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20175 1d2a081c71ed5b989cbf38fe93ae25df 201 SUPERFAMILY SSF55874 64 201 9.15E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS20175 1d2a081c71ed5b989cbf38fe93ae25df 201 Gene3D G3DSA:3.30.565.10 27 201 1.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS19015 f5e398cc2e56efcfb3656b89e124f514 360 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 340 8.2E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19015 f5e398cc2e56efcfb3656b89e124f514 360 Gene3D G3DSA:1.10.3470.10 59 346 1.0E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS03045 9b7c8e6efe35304b0e9e6ca12ded2ec1 495 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 43 479 2.2E-92 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 hmeg3_RS12495 919318034f5b9ac71056c8862dd2ba31 83 Pfam PF04226 Transglycosylase associated protein 34 82 1.0E-13 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 SUPERFAMILY SSF56935 60 701 1.34E-110 T 28-03-2018 hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 177 5.6E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 684 701 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 Pfam PF00593 TonB dependent receptor 263 699 4.4E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 701 6.0E-81 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 Gene3D G3DSA:2.40.170.20 190 701 2.3E-76 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS01525 3ffd2e24779dfcda2fd2f00ead37c13a 701 Gene3D G3DSA:2.170.130.10 36 184 5.7E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 SUPERFAMILY SSF47240 42 184 9.17E-37 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 Pfam PF00210 Ferritin-like domain 47 184 4.9E-27 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 Gene3D G3DSA:1.20.1260.10 18 184 2.1E-41 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 PIRSF PIRSF018063 22 184 6.5E-57 T 28-03-2018 IPR014490 DNA-binding protein from starved cells-like hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 PRINTS PR00601 Bacterioferritin signature 173 184 8.9E-7 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 PRINTS PR00601 Bacterioferritin signature 83 103 8.9E-7 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS18250 5ef3e1bb6d03fe3aab311b99c6af792b 184 PRINTS PR00601 Bacterioferritin signature 42 61 8.9E-7 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 hmeg3_RS07280 0c6ceff0f14b38d87ff116a75f198d3a 748 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 164 2.2E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07280 0c6ceff0f14b38d87ff116a75f198d3a 748 Pfam PF00593 TonB dependent receptor 278 746 1.6E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07280 0c6ceff0f14b38d87ff116a75f198d3a 748 SUPERFAMILY SSF56935 37 236 6.8E-94 T 28-03-2018 hmeg3_RS07280 0c6ceff0f14b38d87ff116a75f198d3a 748 SUPERFAMILY SSF56935 265 748 6.8E-94 T 28-03-2018 hmeg3_RS07280 0c6ceff0f14b38d87ff116a75f198d3a 748 Gene3D G3DSA:2.170.130.10 26 164 4.7E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07280 0c6ceff0f14b38d87ff116a75f198d3a 748 Gene3D G3DSA:2.40.170.20 165 748 2.3E-69 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 Pfam PF06969 HemN C-terminal domain 381 446 9.4E-10 T 28-03-2018 IPR010723 HemN, C-terminal hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 PIRSF PIRSF000167 14 469 2.2E-160 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 SMART SM00729 64 287 6.4E-42 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 Gene3D G3DSA:3.20.20.70 46 370 3.0E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 Pfam PF04055 Radical SAM superfamily 69 242 9.0E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 14 465 6.3E-178 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 hmeg3_RS12190 9c6c6caf82f17c09d06bdccbafafaa30 476 SUPERFAMILY SSF102114 15 458 7.06E-132 T 28-03-2018 hmeg3_RS00205 c84f5df8a7eeaa141b5e2ef71c8593da 234 Pfam PF01227 GTP cyclohydrolase I 53 232 6.6E-55 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 hmeg3_RS00205 c84f5df8a7eeaa141b5e2ef71c8593da 234 Gene3D G3DSA:3.30.1130.10 102 234 3.4E-42 T 28-03-2018 hmeg3_RS00205 c84f5df8a7eeaa141b5e2ef71c8593da 234 SUPERFAMILY SSF55620 17 233 3.56E-66 T 28-03-2018 hmeg3_RS00205 c84f5df8a7eeaa141b5e2ef71c8593da 234 Gene3D G3DSA:1.10.286.10 15 98 3.7E-14 T 28-03-2018 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 Pfam PF02743 Cache domain 36 259 1.1E-24 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 413 565 2.6E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 Gene3D G3DSA:1.10.287.950 294 401 2.3E-10 T 28-03-2018 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 SUPERFAMILY SSF58104 318 599 6.15E-74 T 28-03-2018 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 SMART SM00283 351 598 2.7E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 Gene3D G3DSA:3.30.450.20 21 156 3.1E-18 T 28-03-2018 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 SMART SM00304 296 350 4.8E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 Gene3D G3DSA:3.30.450.20 157 272 4.1E-20 T 28-03-2018 hmeg3_RS06160 da8599ef53f6478f2168363f4ced0dbd 600 Gene3D G3DSA:1.10.287.950 402 600 7.3E-48 T 28-03-2018 hmeg3_RS18670 f26940c82464e447c0798709a44eda87 233 SUPERFAMILY SSF52833 12 102 5.49E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS18670 f26940c82464e447c0798709a44eda87 233 SUPERFAMILY SSF47616 103 229 9.28E-29 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS18670 f26940c82464e447c0798709a44eda87 233 Gene3D G3DSA:1.20.1050.10 120 232 1.2E-24 T 28-03-2018 hmeg3_RS18670 f26940c82464e447c0798709a44eda87 233 Pfam PF00043 Glutathione S-transferase, C-terminal domain 139 221 3.3E-5 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS18670 f26940c82464e447c0798709a44eda87 233 Pfam PF02798 Glutathione S-transferase, N-terminal domain 21 99 5.3E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS18670 f26940c82464e447c0798709a44eda87 233 Gene3D G3DSA:3.40.30.10 9 119 2.3E-28 T 28-03-2018 hmeg3_RS10770 5b0558adfa15165eea124cbb02dcbc99 216 Pfam PF12318 Membrane bound FAD containing D-sorbitol dehydrogenase 22 186 1.3E-40 T 28-03-2018 IPR024651 FAD-containing D-sorbitol dehydrogenase small subunit hmeg3_RS05195 bc7dc61925426b9574d1081765211d8c 127 SUPERFAMILY SSF161084 5 121 1.44E-28 T 28-03-2018 hmeg3_RS05195 bc7dc61925426b9574d1081765211d8c 127 Gene3D G3DSA:1.20.120.550 1 127 3.5E-26 T 28-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain hmeg3_RS05195 bc7dc61925426b9574d1081765211d8c 127 Pfam PF01124 MAPEG family 4 124 5.5E-28 T 28-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 Pfam PF00037 4Fe-4S binding domain 35 56 3.9E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 Pfam PF12800 4Fe-4S binding domain 7 23 0.17 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 1.2E-17 T 28-03-2018 IPR022569 Ferredoxin, C-terminal hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 SUPERFAMILY SSF54862 3 100 1.7E-24 T 28-03-2018 hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 Gene3D G3DSA:3.30.70.20 2 44 3.7E-13 T 28-03-2018 hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 Gene3D G3DSA:3.30.70.20 45 105 1.2E-9 T 28-03-2018 hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.5E-14 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.5E-14 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 hmeg3_RS14590 8ffbb036a57def909213834c38035b01 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.5E-14 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 hmeg3_RS17600 d39a720f445100920586435dd33bcca8 699 SUPERFAMILY SSF55486 16 696 5.23E-193 T 28-03-2018 hmeg3_RS17600 d39a720f445100920586435dd33bcca8 699 Gene3D G3DSA:1.20.1050.40 20 152 3.4E-34 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal hmeg3_RS17600 d39a720f445100920586435dd33bcca8 699 Pfam PF01432 Peptidase family M3 236 696 4.7E-143 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 hmeg3_RS17600 d39a720f445100920586435dd33bcca8 699 Gene3D G3DSA:1.10.1370.10 154 451 9.9E-56 T 28-03-2018 hmeg3_RS17600 d39a720f445100920586435dd33bcca8 699 Gene3D G3DSA:1.10.1370.10 463 699 2.5E-65 T 28-03-2018 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.4E-43 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 PIRSF PIRSF039144 1 112 4.0E-55 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 Gene3D G3DSA:3.30.70.120 1 109 6.7E-50 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 SUPERFAMILY SSF54913 1 112 1.3E-46 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 SMART SM00938 4 105 1.2E-66 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 PRINTS PR00340 P-II protein signature 83 103 5.4E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 PRINTS PR00340 P-II protein signature 23 41 5.4E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 PRINTS PR00340 P-II protein signature 52 75 5.4E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS16870 c6c15877f5b32631859aaef178a2cf2a 112 PRINTS PR00340 P-II protein signature 2 17 5.4E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 hmeg3_RS09465 8626fac200d80d8e74d1c16a0d41dd7b 345 Gene3D G3DSA:3.40.190.10 150 342 1.1E-24 T 28-03-2018 hmeg3_RS09465 8626fac200d80d8e74d1c16a0d41dd7b 345 SUPERFAMILY SSF53850 62 331 3.73E-38 T 28-03-2018 hmeg3_RS09465 8626fac200d80d8e74d1c16a0d41dd7b 345 Gene3D G3DSA:3.40.190.10 45 149 2.7E-14 T 28-03-2018 hmeg3_RS09465 8626fac200d80d8e74d1c16a0d41dd7b 345 Pfam PF09084 NMT1/THI5 like 62 275 7.6E-22 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS23355 0846fdae695fe22c00a07623799fcb56 287 Gene3D G3DSA:1.10.3720.10 35 285 5.3E-33 T 28-03-2018 hmeg3_RS23355 0846fdae695fe22c00a07623799fcb56 287 SUPERFAMILY SSF161098 89 275 2.62E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23355 0846fdae695fe22c00a07623799fcb56 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 269 6.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS13400 1db2b30cc979deaf6bf0ab8a6aa8c7dc 502 Gene3D G3DSA:1.20.1600.10 34 484 1.3E-74 T 28-03-2018 hmeg3_RS13400 1db2b30cc979deaf6bf0ab8a6aa8c7dc 502 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 479 1.3E-115 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS13400 1db2b30cc979deaf6bf0ab8a6aa8c7dc 502 Pfam PF02321 Outer membrane efflux protein 75 266 1.9E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS13400 1db2b30cc979deaf6bf0ab8a6aa8c7dc 502 Pfam PF02321 Outer membrane efflux protein 297 477 3.0E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS13400 1db2b30cc979deaf6bf0ab8a6aa8c7dc 502 SUPERFAMILY SSF56954 14 43 1.7E-91 T 28-03-2018 hmeg3_RS13400 1db2b30cc979deaf6bf0ab8a6aa8c7dc 502 SUPERFAMILY SSF56954 66 481 1.7E-91 T 28-03-2018 hmeg3_RS19410 af3064213e95e380758bc02060282a43 405 Gene3D G3DSA:1.10.260.40 35 124 8.6E-5 T 28-03-2018 hmeg3_RS19410 af3064213e95e380758bc02060282a43 405 Pfam PF06114 IrrE N-terminal-like domain 251 369 4.0E-9 T 28-03-2018 IPR010359 IrrE N-terminal-like domain hmeg3_RS04265 01fc92bab7aa7974259a43d63744e47e 106 Pfam PF13453 Transcription factor zinc-finger 2 43 1.2E-21 T 28-03-2018 IPR027392 Transcription factor zinc-finger hmeg3_RS03945 481c5927ea39b3977d0b5f13acd3ef2c 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 450 5.9E-81 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS03945 481c5927ea39b3977d0b5f13acd3ef2c 529 SUPERFAMILY SSF53850 34 516 9.56E-111 T 28-03-2018 hmeg3_RS03945 481c5927ea39b3977d0b5f13acd3ef2c 529 Gene3D G3DSA:3.90.76.10 53 166 1.1E-30 T 28-03-2018 hmeg3_RS03945 481c5927ea39b3977d0b5f13acd3ef2c 529 PIRSF PIRSF002741 8 520 1.0E-95 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS03945 481c5927ea39b3977d0b5f13acd3ef2c 529 Gene3D G3DSA:3.40.190.10 167 308 2.1E-29 T 28-03-2018 hmeg3_RS03945 481c5927ea39b3977d0b5f13acd3ef2c 529 Gene3D G3DSA:3.10.105.10 309 501 9.4E-37 T 28-03-2018 hmeg3_RS21705 6e1abd515ea481404fb60400fe82c46e 251 Gene3D G3DSA:3.40.190.10 27 74 0.0012 T 28-03-2018 hmeg3_RS21705 6e1abd515ea481404fb60400fe82c46e 251 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 16 230 8.3E-91 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 hmeg3_RS21705 6e1abd515ea481404fb60400fe82c46e 251 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 7 231 39.719 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 hmeg3_RS21705 6e1abd515ea481404fb60400fe82c46e 251 Pfam PF00912 Transglycosylase 59 225 1.6E-53 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS21705 6e1abd515ea481404fb60400fe82c46e 251 SUPERFAMILY SSF53955 58 229 3.94E-59 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS21705 6e1abd515ea481404fb60400fe82c46e 251 Gene3D G3DSA:1.10.3810.10 75 237 6.7E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 hmeg3_RS13425 c4f1e8c62111a64e214b7c9c27bc16be 153 Pfam PF02391 MoaE protein 6 119 4.2E-38 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS13425 c4f1e8c62111a64e214b7c9c27bc16be 153 SUPERFAMILY SSF54690 3 148 6.28E-54 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS13425 c4f1e8c62111a64e214b7c9c27bc16be 153 Gene3D G3DSA:3.90.1170.40 1 148 3.7E-61 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 180 193 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 211 39.196 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 PIRSF PIRSF000190 1 211 6.4E-80 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 211 1.9E-86 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 170 211 6.8E-20 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 Gene3D G3DSA:2.30.110.10 10 211 4.6E-73 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 SUPERFAMILY SSF50475 6 211 1.52E-66 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS20025 3ef9e612df80a5fd8996ccd94e21d648 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 118 1.3E-27 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 Gene3D G3DSA:3.40.1080.10 233 520 4.8E-40 T 28-03-2018 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 8 555 7.8E-291 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 SUPERFAMILY SSF100950 45 278 5.58E-29 T 28-03-2018 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 Gene3D G3DSA:3.40.1080.10 3 223 3.4E-29 T 28-03-2018 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 8 555 4.4E-296 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 SUPERFAMILY SSF100950 228 387 3.77E-21 T 28-03-2018 hmeg3_RS12690 bb6bc157434c9146d501eccc3faf9717 555 SUPERFAMILY SSF100950 416 483 3.77E-21 T 28-03-2018 hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 Gene3D G3DSA:1.10.357.10 96 210 3.8E-23 T 28-03-2018 hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 Gene3D G3DSA:1.10.10.60 14 50 7.3E-9 T 28-03-2018 hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 Gene3D G3DSA:1.10.260.40 51 95 3.2E-7 T 28-03-2018 hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 41 71 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 SUPERFAMILY SSF46689 16 99 4.77E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS06500 3fd60540361e29cad9425b7893ef2c46 210 SUPERFAMILY SSF48498 96 209 7.63E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS08255 817704f23e459655b4097129e60ec0ec 406 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 49 268 2.8E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS08255 817704f23e459655b4097129e60ec0ec 406 SUPERFAMILY SSF111369 54 241 2.62E-23 T 28-03-2018 hmeg3_RS08255 817704f23e459655b4097129e60ec0ec 406 Gene3D G3DSA:1.20.1600.10 7 326 3.2E-33 T 28-03-2018 hmeg3_RS08255 817704f23e459655b4097129e60ec0ec 406 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 387 2.2E-52 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS12505 9ad84034e6758c7619cdaf19a020f444 331 Gene3D G3DSA:3.40.630.10 6 284 2.3E-35 T 28-03-2018 hmeg3_RS12505 9ad84034e6758c7619cdaf19a020f444 331 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 52 74 - T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 hmeg3_RS12505 9ad84034e6758c7619cdaf19a020f444 331 Pfam PF00246 Zinc carboxypeptidase 38 237 2.6E-17 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 hmeg3_RS12505 9ad84034e6758c7619cdaf19a020f444 331 SUPERFAMILY SSF53187 37 310 7.28E-49 T 28-03-2018 hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 SMART SM00382 422 630 1.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 279 1.2E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 SUPERFAMILY SSF52540 397 644 5.84E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 Gene3D G3DSA:3.40.50.300 391 647 6.4E-56 T 28-03-2018 hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 Gene3D G3DSA:1.10.3470.10 15 303 1.3E-42 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 622 644 1.4E-12 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS13680 48e3a7e646303f4e7c27108149f1f338 657 Pfam PF00005 ABC transporter 413 573 3.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS20900 7fea1a5d84183b541117dfb5c88324c9 281 Gene3D G3DSA:1.10.3720.10 72 269 1.1E-24 T 28-03-2018 hmeg3_RS20900 7fea1a5d84183b541117dfb5c88324c9 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 268 2.5E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS20900 7fea1a5d84183b541117dfb5c88324c9 281 SUPERFAMILY SSF161098 77 260 4.84E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 SUPERFAMILY SSF53822 35 381 3.21E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 Gene3D G3DSA:3.40.50.2300 160 332 8.4E-22 T 28-03-2018 hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 Pfam PF13458 Periplasmic binding protein 36 378 2.4E-59 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 Gene3D G3DSA:3.40.50.2300 21 159 2.4E-22 T 28-03-2018 hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 263 281 2.9E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 35 51 2.9E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS16865 361df3d8f6fa7a936ad592ca2cc8b708 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 57 73 2.9E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS00115 bea7171e850c03d1cb4f66149753d276 299 Pfam PF00561 alpha/beta hydrolase fold 48 279 6.9E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS00115 bea7171e850c03d1cb4f66149753d276 299 SUPERFAMILY SSF53474 25 292 2.03E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00115 bea7171e850c03d1cb4f66149753d276 299 Gene3D G3DSA:3.40.50.1820 20 293 3.7E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS10280 c8b01d7016ac83d44db8f352907e4392 205 SMART SM00479 5 173 8.6E-41 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS10280 c8b01d7016ac83d44db8f352907e4392 205 SUPERFAMILY SSF53098 3 173 2.4E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS10280 c8b01d7016ac83d44db8f352907e4392 205 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 7 166 1.1E-24 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS10280 c8b01d7016ac83d44db8f352907e4392 205 Gene3D G3DSA:3.30.420.10 4 179 1.3E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS10280 c8b01d7016ac83d44db8f352907e4392 205 Pfam PF00929 Exonuclease 7 164 2.3E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III hmeg3_RS19980 67f946f18d440013986d70f59ed9adb0 234 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 156 231 5.4E-15 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 hmeg3_RS19980 67f946f18d440013986d70f59ed9adb0 234 Gene3D G3DSA:3.30.1150.10 62 234 2.1E-18 T 28-03-2018 hmeg3_RS19980 67f946f18d440013986d70f59ed9adb0 234 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 154 232 2.1E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 hmeg3_RS19980 67f946f18d440013986d70f59ed9adb0 234 SUPERFAMILY SSF74653 150 230 7.72E-20 T 28-03-2018 hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 SUPERFAMILY SSF111304 3 196 1.01E-71 T 28-03-2018 IPR023627 Recombination protein RecR hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 Gene3D G3DSA:1.10.150.20 1 32 0.0095 T 28-03-2018 hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 95.473 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 SMART SM00493 80 165 4.8E-11 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 Pfam PF02132 RecR protein 40 78 4.9E-12 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 Pfam PF13662 Toprim domain 81 171 2.8E-24 T 28-03-2018 IPR006171 TOPRIM domain hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 TIGRFAM TIGR00615 recR: recombination protein RecR 3 196 3.9E-69 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 hmeg3_RS17905 281636ddc666a7fdea4d6c425c7d2dfe 198 Gene3D G3DSA:3.40.1360.10 77 170 6.8E-35 T 28-03-2018 hmeg3_RS17615 7c9936637ff3ae513c3cd44b716fafeb 435 Pfam PF01266 FAD dependent oxidoreductase 2 407 1.0E-60 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS17615 7c9936637ff3ae513c3cd44b716fafeb 435 SUPERFAMILY SSF54373 279 369 4.05E-14 T 28-03-2018 hmeg3_RS17615 7c9936637ff3ae513c3cd44b716fafeb 435 Gene3D G3DSA:3.50.50.60 1 427 3.7E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17615 7c9936637ff3ae513c3cd44b716fafeb 435 SUPERFAMILY SSF51905 1 54 1.29E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17615 7c9936637ff3ae513c3cd44b716fafeb 435 SUPERFAMILY SSF51905 369 425 1.29E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS17615 7c9936637ff3ae513c3cd44b716fafeb 435 SUPERFAMILY SSF51905 107 279 1.29E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 Pfam PF13307 Helicase C-terminal domain 490 647 1.8E-30 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 Pfam PF00270 DEAD/DEAH box helicase 47 251 1.1E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SMART SM00491 504 634 1.4E-33 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 Gene3D G3DSA:3.40.50.300 461 667 1.2E-12 T 28-03-2018 hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SUPERFAMILY SSF52540 593 630 3.91E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SUPERFAMILY SSF52540 32 127 3.91E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SUPERFAMILY SSF52540 204 258 3.91E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 Gene3D G3DSA:3.40.50.300 37 440 5.9E-31 T 28-03-2018 hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SUPERFAMILY SSF52540 604 619 2.21E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SUPERFAMILY SSF52540 171 247 2.21E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08810 699d871c8ece7ab9904becce6b879079 674 SUPERFAMILY SSF52540 397 573 2.21E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19600 0f8906746b5e61de1166080be13df28e 312 Gene3D G3DSA:3.60.21.10 47 296 4.4E-37 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS19600 0f8906746b5e61de1166080be13df28e 312 SUPERFAMILY SSF56300 49 269 5.93E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS19600 0f8906746b5e61de1166080be13df28e 312 Pfam PF00149 Calcineurin-like phosphoesterase 53 240 2.3E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS10495 eef98c8084fb8a8ee8396aab4ec56a3a 160 Pfam PF05229 Spore Coat Protein U domain 24 156 1.1E-27 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS10495 eef98c8084fb8a8ee8396aab4ec56a3a 160 SMART SM00972 93 157 5.2E-12 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS09440 5d2d7e0133f0367b10166028eca48e04 263 Gene3D G3DSA:3.40.190.10 23 121 2.2E-19 T 28-03-2018 hmeg3_RS09440 5d2d7e0133f0367b10166028eca48e04 263 Pfam PF03180 NLPA lipoprotein 27 263 6.2E-92 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS09440 5d2d7e0133f0367b10166028eca48e04 263 Gene3D G3DSA:3.40.190.10 122 263 7.8E-57 T 28-03-2018 hmeg3_RS09440 5d2d7e0133f0367b10166028eca48e04 263 SUPERFAMILY SSF53850 26 263 1.71E-78 T 28-03-2018 hmeg3_RS09440 5d2d7e0133f0367b10166028eca48e04 263 PIRSF PIRSF002854 2 263 3.6E-97 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 Gene3D G3DSA:3.40.30.10 1 85 3.9E-23 T 28-03-2018 hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 Gene3D G3DSA:1.20.1050.10 86 145 4.5E-15 T 28-03-2018 hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 Gene3D G3DSA:1.20.1050.10 146 200 5.6E-18 T 28-03-2018 hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 79 2.3E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 SUPERFAMILY SSF52833 2 83 2.59E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 Pfam PF00043 Glutathione S-transferase, C-terminal domain 109 196 6.4E-16 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS08560 b9e9c7f675809b7a482f2fef1f9f9096 230 SUPERFAMILY SSF47616 77 201 4.23E-39 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS11370 831a9f0677e51ec7e28d2a5b2879ad11 195 Gene3D G3DSA:1.20.1260.10 39 191 3.7E-29 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS11370 831a9f0677e51ec7e28d2a5b2879ad11 195 Pfam PF13628 Domain of unknown function (DUF4142) 51 187 8.0E-46 T 28-03-2018 IPR025419 Domain of unknown function DUF4142 hmeg3_RS24340 e7854a9de068c5d1f73a3536dad637f1 306 Gene3D G3DSA:3.40.50.720 126 284 5.6E-32 T 28-03-2018 hmeg3_RS24340 e7854a9de068c5d1f73a3536dad637f1 306 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 302 1.6E-47 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 hmeg3_RS24340 e7854a9de068c5d1f73a3536dad637f1 306 PIRSF PIRSF001439 1 305 3.2E-66 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 hmeg3_RS24340 e7854a9de068c5d1f73a3536dad637f1 306 SUPERFAMILY SSF51735 2 304 2.77E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS24340 e7854a9de068c5d1f73a3536dad637f1 306 Gene3D G3DSA:3.30.1780.10 1 125 1.3E-34 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 hmeg3_RS18855 b17d22ddd8ed600dad0068076289162b 306 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 284 4.1E-60 T 28-03-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 318 4.5E-15 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 Gene3D G3DSA:3.40.50.720 120 289 1.1E-45 T 28-03-2018 hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 Gene3D G3DSA:3.40.50.720 10 119 9.4E-22 T 28-03-2018 hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 SUPERFAMILY SSF52283 17 135 2.34E-16 T 28-03-2018 hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 286 2.0E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS05920 d2adb39627c39bbeb229f88df61763c6 335 SUPERFAMILY SSF51735 107 287 2.25E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS10320 4fcdbf8f557f19f9bc41fa991bfdb45e 326 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 4 326 33.118 T 28-03-2018 IPR003770 Endolytic murein transglycosylase hmeg3_RS10320 4fcdbf8f557f19f9bc41fa991bfdb45e 326 Gene3D G3DSA:3.30.160.60 64 103 1.1E-10 T 28-03-2018 hmeg3_RS10320 4fcdbf8f557f19f9bc41fa991bfdb45e 326 Gene3D G3DSA:3.30.160.60 298 326 1.3E-12 T 28-03-2018 hmeg3_RS10320 4fcdbf8f557f19f9bc41fa991bfdb45e 326 Pfam PF02618 YceG-like family 37 323 3.5E-82 T 28-03-2018 IPR003770 Endolytic murein transglycosylase hmeg3_RS10320 4fcdbf8f557f19f9bc41fa991bfdb45e 326 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 7 324 4.8E-84 T 28-03-2018 IPR003770 Endolytic murein transglycosylase hmeg3_RS08710 dfd99cc80df0c886d9896be93767a3f9 168 Pfam PF01584 CheW-like domain 22 158 2.9E-37 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS08710 dfd99cc80df0c886d9896be93767a3f9 168 SUPERFAMILY SSF50341 21 160 1.57E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS08710 dfd99cc80df0c886d9896be93767a3f9 168 Gene3D G3DSA:2.40.50.180 39 103 1.5E-19 T 28-03-2018 hmeg3_RS08710 dfd99cc80df0c886d9896be93767a3f9 168 SMART SM00260 18 155 6.3E-43 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS08710 dfd99cc80df0c886d9896be93767a3f9 168 Gene3D G3DSA:2.30.30.40 104 149 4.2E-18 T 28-03-2018 hmeg3_RS07190 f8e234deb0442ce2f2d9b194f08985cf 178 Gene3D G3DSA:1.10.3760.10 69 178 1.9E-35 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 hmeg3_RS07190 f8e234deb0442ce2f2d9b194f08985cf 178 PIRSF PIRSF006162 19 178 1.4E-41 T 28-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 hmeg3_RS07190 f8e234deb0442ce2f2d9b194f08985cf 178 Pfam PF04608 Phosphatidylglycerophosphatase A 29 175 5.7E-46 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 hmeg3_RS07190 f8e234deb0442ce2f2d9b194f08985cf 178 SUPERFAMILY SSF101307 23 175 8.89E-37 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 hmeg3_RS23755 f1ce282fc8d4e1e9ac8da45d21220b7f 217 Pfam PF13302 Acetyltransferase (GNAT) domain 23 160 2.2E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS23755 f1ce282fc8d4e1e9ac8da45d21220b7f 217 Gene3D G3DSA:3.40.630.30 8 192 7.2E-29 T 28-03-2018 hmeg3_RS23755 f1ce282fc8d4e1e9ac8da45d21220b7f 217 SUPERFAMILY SSF55729 13 184 6.62E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 SUPERFAMILY SSF52540 8 242 7.16E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 Gene3D G3DSA:3.40.50.300 6 242 3.0E-57 T 28-03-2018 hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 SUPERFAMILY SSF52317 254 447 6.21E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 486 202.403 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 Gene3D G3DSA:3.40.50.880 243 483 1.1E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 Pfam PF13500 AAA domain 7 235 9.0E-23 T 28-03-2018 hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 9 471 2.6E-147 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 hmeg3_RS12360 44b9a0c666cb8c206a8f0d82c12e8d33 486 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 437 4.4E-58 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 hmeg3_RS13560 75c31a30f502019cf1e727655f8d35fc 123 Gene3D G3DSA:3.10.180.10 2 122 9.8E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS13560 75c31a30f502019cf1e727655f8d35fc 123 SUPERFAMILY SSF54593 1 118 1.88E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS10645 7b20355b376b6c0cdd7d79f8a3f08b70 258 SUPERFAMILY SSF54534 110 219 7.2E-28 T 28-03-2018 hmeg3_RS10645 7b20355b376b6c0cdd7d79f8a3f08b70 258 SUPERFAMILY SSF109998 25 159 2.43E-23 T 28-03-2018 IPR027304 Trigger factor/SurA domain hmeg3_RS10645 7b20355b376b6c0cdd7d79f8a3f08b70 258 Gene3D G3DSA:3.10.50.40 120 245 3.9E-39 T 28-03-2018 hmeg3_RS10645 7b20355b376b6c0cdd7d79f8a3f08b70 258 Pfam PF13616 PPIC-type PPIASE domain 127 220 2.5E-22 T 28-03-2018 hmeg3_RS15765 4e004e0edd533674e0708ec374e9eeac 377 SUPERFAMILY SSF140693 165 367 1.15E-39 T 28-03-2018 IPR009483 Invasion plasmid antigen IpaD GO:0009405 hmeg3_RS15765 4e004e0edd533674e0708ec374e9eeac 377 Gene3D G3DSA:1.20.1710.10 135 377 4.3E-61 T 28-03-2018 hmeg3_RS15765 4e004e0edd533674e0708ec374e9eeac 377 Pfam PF06511 Invasion plasmid antigen IpaD 147 375 8.4E-37 T 28-03-2018 IPR009483 Invasion plasmid antigen IpaD GO:0009405 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Gene3D G3DSA:3.30.450.20 154 218 0.014 T 28-03-2018 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 SUPERFAMILY SSF55874 319 477 2.49E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 478 9.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Gene3D G3DSA:3.30.450.20 7 153 3.2E-18 T 28-03-2018 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Gene3D G3DSA:3.30.565.10 328 479 1.4E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 SUPERFAMILY SSF55785 16 144 1.29E-12 T 28-03-2018 IPR000014 PAS domain hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Gene3D G3DSA:1.10.287.130 219 325 1.2E-11 T 28-03-2018 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Pfam PF13426 PAS domain 32 151 1.8E-6 T 28-03-2018 IPR000014 PAS domain hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 328 1.1E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 SUPERFAMILY SSF47384 297 327 5.49E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 SUPERFAMILY SSF47384 222 262 5.49E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 SMART SM00387 370 479 8.8E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 1.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 1.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 1.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS03635 34d8cd1edeef0fefc93f4a888712d845 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.5E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS11225 18df2a285e2b242ba90dc5f310b59d45 196 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 63 142 5.6E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11225 18df2a285e2b242ba90dc5f310b59d45 196 SUPERFAMILY SSF46626 37 172 3.01E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11225 18df2a285e2b242ba90dc5f310b59d45 196 Gene3D G3DSA:1.10.760.10 33 184 8.2E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS06700 e8626910f3dc8613ed997f926f93d203 429 Pfam PF05977 Transmembrane secretion effector 12 393 6.5E-6 T 28-03-2018 IPR010290 Transmembrane secretion effector hmeg3_RS06700 e8626910f3dc8613ed997f926f93d203 429 SUPERFAMILY SSF103473 7 396 1.7E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS06700 e8626910f3dc8613ed997f926f93d203 429 Gene3D G3DSA:1.20.1250.20 210 410 2.3E-13 T 28-03-2018 hmeg3_RS06700 e8626910f3dc8613ed997f926f93d203 429 Gene3D G3DSA:1.20.1250.20 4 191 2.0E-7 T 28-03-2018 hmeg3_RS24425 6c5b0c73dd2b48b77ef446a1243e9c45 312 Gene3D G3DSA:1.10.3720.10 2 300 4.9E-46 T 28-03-2018 hmeg3_RS24425 6c5b0c73dd2b48b77ef446a1243e9c45 312 SUPERFAMILY SSF161098 89 297 1.28E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24425 6c5b0c73dd2b48b77ef446a1243e9c45 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 311 3.7E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 PRINTS PR00689 Acyl-coA-binding protein signature 4 19 1.5E-19 T 28-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 PRINTS PR00689 Acyl-coA-binding protein signature 44 59 1.5E-19 T 28-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 PRINTS PR00689 Acyl-coA-binding protein signature 65 82 1.5E-19 T 28-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 PRINTS PR00689 Acyl-coA-binding protein signature 21 39 1.5E-19 T 28-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 Pfam PF00887 Acyl CoA binding protein 4 82 8.9E-27 T 28-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 SUPERFAMILY SSF47027 3 82 7.19E-27 T 28-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 hmeg3_RS14565 c0792f3d1f2ebc83414569fa17451131 84 Gene3D G3DSA:1.20.80.10 1 84 2.2E-29 T 28-03-2018 IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle hmeg3_RS14135 897133b954494765211e385a3e30c10d 178 PIRSF PIRSF014995 9 178 8.7E-66 T 28-03-2018 IPR014469 Protein of unknown function DUF2271 hmeg3_RS14135 897133b954494765211e385a3e30c10d 178 Pfam PF10029 Predicted periplasmic protein (DUF2271) 30 170 8.9E-52 T 28-03-2018 IPR014469 Protein of unknown function DUF2271 hmeg3_RS18355 98189fd3796afdd7d83bb6d66788981c 132 SUPERFAMILY SSF52038 33 125 1.83E-20 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) hmeg3_RS18355 98189fd3796afdd7d83bb6d66788981c 132 Gene3D G3DSA:3.30.370.10 35 129 1.0E-18 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) hmeg3_RS18355 98189fd3796afdd7d83bb6d66788981c 132 Pfam PF01337 Barstar (barnase inhibitor) 39 120 3.3E-25 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) hmeg3_RS18600 fd934c0bfaaa803ff781ff07151b9adc 86 Gene3D G3DSA:3.30.160.140 6 73 1.1E-4 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 hmeg3_RS08815 7398e060d2b3bcbfd3eef760f75f5fd1 313 Gene3D G3DSA:2.40.10.220 203 312 2.2E-9 T 28-03-2018 hmeg3_RS08815 7398e060d2b3bcbfd3eef760f75f5fd1 313 Pfam PF12945 Flagellar protein YcgR 111 194 1.7E-15 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal hmeg3_RS08815 7398e060d2b3bcbfd3eef760f75f5fd1 313 Pfam PF07238 PilZ domain 203 307 5.4E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 hmeg3_RS08815 7398e060d2b3bcbfd3eef760f75f5fd1 313 Gene3D G3DSA:2.30.110.10 110 202 1.5E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS08815 7398e060d2b3bcbfd3eef760f75f5fd1 313 SUPERFAMILY SSF141371 111 204 2.59E-13 T 28-03-2018 hmeg3_RS17355 1ac0a3fa1b0a959d5212106bda5fc1b5 448 Gene3D G3DSA:3.40.190.10 141 271 4.4E-15 T 28-03-2018 hmeg3_RS17355 1ac0a3fa1b0a959d5212106bda5fc1b5 448 Gene3D G3DSA:3.40.190.10 52 140 1.9E-7 T 28-03-2018 hmeg3_RS17355 1ac0a3fa1b0a959d5212106bda5fc1b5 448 Pfam PF16868 NMT1-like family 68 295 7.8E-17 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family hmeg3_RS17355 1ac0a3fa1b0a959d5212106bda5fc1b5 448 SUPERFAMILY SSF53850 53 330 8.95E-43 T 28-03-2018 hmeg3_RS21270 5ad3f469a300e18e708ddf31088cd696 256 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 255 1.6E-138 T 28-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 hmeg3_RS21270 5ad3f469a300e18e708ddf31088cd696 256 Pfam PF00483 Nucleotidyl transferase 2 209 7.9E-20 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS21270 5ad3f469a300e18e708ddf31088cd696 256 Gene3D G3DSA:3.90.550.10 1 256 3.2E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21270 5ad3f469a300e18e708ddf31088cd696 256 SUPERFAMILY SSF53448 1 255 6.47E-69 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS14755 d7163b3105e81282fee196fbc5ce1322 613 SUPERFAMILY SSF52540 1 353 2.55E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14755 d7163b3105e81282fee196fbc5ce1322 613 Gene3D G3DSA:3.40.50.300 1 373 1.5E-23 T 28-03-2018 hmeg3_RS14755 d7163b3105e81282fee196fbc5ce1322 613 Pfam PF13175 AAA ATPase domain 234 340 1.6E-13 T 28-03-2018 hmeg3_RS14755 d7163b3105e81282fee196fbc5ce1322 613 Pfam PF13175 AAA ATPase domain 1 63 1.8E-9 T 28-03-2018 hmeg3_RS05915 3766533ebe8b06a7fb8d430cd34ed628 199 PRINTS PR01021 OMPA domain signature 128 143 1.0E-8 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS05915 3766533ebe8b06a7fb8d430cd34ed628 199 PRINTS PR01021 OMPA domain signature 143 159 1.0E-8 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS05915 3766533ebe8b06a7fb8d430cd34ed628 199 PRINTS PR01021 OMPA domain signature 98 120 1.0E-8 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 hmeg3_RS05915 3766533ebe8b06a7fb8d430cd34ed628 199 Gene3D G3DSA:3.30.1330.60 65 199 3.7E-20 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS05915 3766533ebe8b06a7fb8d430cd34ed628 199 Pfam PF00691 OmpA family 97 185 1.2E-12 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS05915 3766533ebe8b06a7fb8d430cd34ed628 199 SUPERFAMILY SSF103088 87 198 3.4E-21 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS18645 85202839a8fc117b1eeba123923e634e 318 Pfam PF00892 EamA-like transporter family 12 117 9.3E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS18645 85202839a8fc117b1eeba123923e634e 318 Pfam PF00892 EamA-like transporter family 164 303 8.6E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS18645 85202839a8fc117b1eeba123923e634e 318 SUPERFAMILY SSF103481 229 305 1.14E-5 T 28-03-2018 hmeg3_RS18645 85202839a8fc117b1eeba123923e634e 318 SUPERFAMILY SSF103481 51 122 9.55E-5 T 28-03-2018 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 323 36.387 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 1.8E-35 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 2.7E-48 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 SUPERFAMILY SSF48179 180 332 2.72E-54 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 Gene3D G3DSA:3.40.50.720 1 180 1.0E-26 T 28-03-2018 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 SUPERFAMILY SSF51735 1 181 3.53E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 PIRSF PIRSF000114 1 333 1.3E-96 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 1.9E-37 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 1.9E-37 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 1.9E-37 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 1.9E-37 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 1.9E-37 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 hmeg3_RS22605 6be00f4eaefcc670b4aac2eecb5f3e1c 333 Gene3D G3DSA:1.10.1040.10 181 328 1.0E-50 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS17840 4d5076d4a0d3d3158693753f060cb392 128 Gene3D G3DSA:3.40.30.10 24 128 5.8E-23 T 28-03-2018 hmeg3_RS17840 4d5076d4a0d3d3158693753f060cb392 128 Pfam PF00085 Thioredoxin 30 126 9.1E-17 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 hmeg3_RS17840 4d5076d4a0d3d3158693753f060cb392 128 ProSitePatterns PS00194 Thioredoxin family active site. 44 62 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 hmeg3_RS17840 4d5076d4a0d3d3158693753f060cb392 128 SUPERFAMILY SSF52833 36 128 1.42E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03120 fbb9b55a2916bf5985d2ba4840992bd6 214 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 188 4.0E-40 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS03120 fbb9b55a2916bf5985d2ba4840992bd6 214 SMART SM01007 9 189 6.2E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS03120 fbb9b55a2916bf5985d2ba4840992bd6 214 SUPERFAMILY SSF53639 4 211 2.75E-53 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS03120 fbb9b55a2916bf5985d2ba4840992bd6 214 Gene3D G3DSA:3.40.225.10 3 200 4.9E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal hmeg3_RS08915 6a2a1403d2ea8d0bc375549e7553694e 383 Gene3D G3DSA:3.30.930.10 16 306 7.0E-44 T 28-03-2018 hmeg3_RS08915 6a2a1403d2ea8d0bc375549e7553694e 383 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 317 9.8E-89 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 hmeg3_RS08915 6a2a1403d2ea8d0bc375549e7553694e 383 SUPERFAMILY SSF55681 4 321 5.21E-61 T 28-03-2018 hmeg3_RS08915 6a2a1403d2ea8d0bc375549e7553694e 383 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 364 35.741 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 hmeg3_RS08915 6a2a1403d2ea8d0bc375549e7553694e 383 PIRSF PIRSF001549 6 339 9.4E-42 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 hmeg3_RS08915 6a2a1403d2ea8d0bc375549e7553694e 383 Pfam PF13393 Histidyl-tRNA synthetase 10 313 2.3E-119 T 28-03-2018 hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 Pfam PF01799 [2Fe-2S] binding domain 72 145 2.5E-25 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 Gene3D G3DSA:3.10.20.30 2 73 1.2E-25 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 60 7.7E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 SUPERFAMILY SSF47741 83 150 4.71E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 SUPERFAMILY SSF54292 3 76 4.06E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS12625 64add89e7adf2480defc0ee2748e922b 155 Gene3D G3DSA:1.10.150.120 74 155 4.3E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS21165 3491fe0b2e8c384afc6d8b4eecd68854 269 SUPERFAMILY SSF53448 14 208 6.38E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21165 3491fe0b2e8c384afc6d8b4eecd68854 269 Pfam PF00535 Glycosyl transferase family 2 16 100 2.0E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS21165 3491fe0b2e8c384afc6d8b4eecd68854 269 Gene3D G3DSA:3.90.550.10 13 215 2.5E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS00765 f88a38c2d01af30e55aa98789883b5df 198 SUPERFAMILY SSF53697 4 192 2.22E-57 T 28-03-2018 hmeg3_RS00765 f88a38c2d01af30e55aa98789883b5df 198 Pfam PF13580 SIS domain 15 145 5.9E-36 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS00765 f88a38c2d01af30e55aa98789883b5df 198 Gene3D G3DSA:3.40.50.10490 1 194 6.3E-41 T 28-03-2018 hmeg3_RS00765 f88a38c2d01af30e55aa98789883b5df 198 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 191 36.657 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 hmeg3_RS15270 2c53a27fe230422eccb646424501e607 239 Gene3D G3DSA:1.20.5.590 33 63 0.001 T 28-03-2018 hmeg3_RS15270 2c53a27fe230422eccb646424501e607 239 Gene3D G3DSA:1.10.287.500 65 197 5.3E-16 T 28-03-2018 hmeg3_RS15270 2c53a27fe230422eccb646424501e607 239 SUPERFAMILY SSF75708 38 238 6.02E-53 T 28-03-2018 hmeg3_RS15270 2c53a27fe230422eccb646424501e607 239 Pfam PF04344 Chemotaxis phosphatase, CheZ 45 239 4.5E-60 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 hmeg3_RS15270 2c53a27fe230422eccb646424501e607 239 PIRSF PIRSF002884 23 239 2.0E-57 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 hmeg3_RS16580 ee1f09cd70767e5dcdc1ffc3f03fc496 294 Hamap MF_00188 Protease HtpX [htpX]. 1 291 24.758 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 hmeg3_RS16580 ee1f09cd70767e5dcdc1ffc3f03fc496 294 Gene3D G3DSA:3.30.2010.10 70 162 1.5E-20 T 28-03-2018 hmeg3_RS16580 ee1f09cd70767e5dcdc1ffc3f03fc496 294 Pfam PF01435 Peptidase family M48 80 291 2.7E-38 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 hmeg3_RS18875 059167db765b249ea7d3f118acb37e1f 476 Pfam PF00171 Aldehyde dehydrogenase family 22 470 1.4E-148 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18875 059167db765b249ea7d3f118acb37e1f 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18875 059167db765b249ea7d3f118acb37e1f 476 Gene3D G3DSA:3.40.605.10 2 264 5.6E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18875 059167db765b249ea7d3f118acb37e1f 476 Gene3D G3DSA:3.40.309.10 265 456 4.5E-59 T 28-03-2018 hmeg3_RS18875 059167db765b249ea7d3f118acb37e1f 476 SUPERFAMILY SSF53720 4 473 1.57E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS21945 ace0aa4cc58a4ae2f165c0066f05104e 411 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 411 3.4E-121 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS21945 ace0aa4cc58a4ae2f165c0066f05104e 411 Gene3D G3DSA:3.60.70.12 9 282 5.8E-100 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS21945 ace0aa4cc58a4ae2f165c0066f05104e 411 SUPERFAMILY SSF56266 16 408 1.05E-136 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS21945 ace0aa4cc58a4ae2f165c0066f05104e 411 Pfam PF01960 ArgJ family 23 411 7.9E-142 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS21945 ace0aa4cc58a4ae2f165c0066f05104e 411 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 411 154.848 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 hmeg3_RS21945 ace0aa4cc58a4ae2f165c0066f05104e 411 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 409 2.0E-161 T 28-03-2018 hmeg3_RS04970 d3c57a08c85320087848d1e3124676bc 154 Gene3D G3DSA:3.30.1330.40 1 152 7.8E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS04970 d3c57a08c85320087848d1e3124676bc 154 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 4 148 9.1E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS04970 d3c57a08c85320087848d1e3124676bc 154 SUPERFAMILY SSF55298 1 151 3.93E-45 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS17580 e8f3cb4d7f84c485dd9743287d7edc4b 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 109 6.1E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS17580 e8f3cb4d7f84c485dd9743287d7edc4b 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 204 3.7E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17580 e8f3cb4d7f84c485dd9743287d7edc4b 223 SUPERFAMILY SSF161098 14 200 4.84E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17580 e8f3cb4d7f84c485dd9743287d7edc4b 223 Gene3D G3DSA:1.10.3720.10 5 221 7.9E-33 T 28-03-2018 hmeg3_RS16950 f16c697c480e8810e7b40f669998dd59 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 18 265 4.5E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16950 f16c697c480e8810e7b40f669998dd59 296 Gene3D G3DSA:1.10.3470.10 6 273 1.7E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS02940 bbce5191c4ddbf622c8ca8dbf17c72c9 156 SUPERFAMILY SSF158442 8 150 4.05E-36 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain hmeg3_RS02940 bbce5191c4ddbf622c8ca8dbf17c72c9 156 Gene3D G3DSA:1.20.1550.10 1 155 1.0E-38 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain hmeg3_RS02940 bbce5191c4ddbf622c8ca8dbf17c72c9 156 Pfam PF02600 Disulfide bond formation protein DsbB 5 149 1.4E-38 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 hmeg3_RS02940 bbce5191c4ddbf622c8ca8dbf17c72c9 156 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 1 156 18.598 T 28-03-2018 IPR022920 Disulphide bond formation protein DsbB hmeg3_RS02130 0c46ab78007ae1600715a2749618d65a 128 SUPERFAMILY SSF81296 25 128 4.69E-29 T 28-03-2018 IPR014756 Immunoglobulin E-set hmeg3_RS02130 0c46ab78007ae1600715a2749618d65a 128 Pfam PF04234 CopC domain 26 127 3.5E-22 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 hmeg3_RS02130 0c46ab78007ae1600715a2749618d65a 128 Gene3D G3DSA:2.60.40.1220 25 128 2.9E-25 T 28-03-2018 hmeg3_RS10375 af1f7a9e969afa68ec5103e83ba17f63 380 SUPERFAMILY SSF51395 5 195 1.83E-105 T 28-03-2018 hmeg3_RS10375 af1f7a9e969afa68ec5103e83ba17f63 380 SUPERFAMILY SSF51395 224 375 1.83E-105 T 28-03-2018 hmeg3_RS10375 af1f7a9e969afa68ec5103e83ba17f63 380 Gene3D G3DSA:3.20.20.70 3 380 1.7E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS10375 af1f7a9e969afa68ec5103e83ba17f63 380 Pfam PF01070 FMN-dependent dehydrogenase 14 376 4.9E-132 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 hmeg3_RS10375 af1f7a9e969afa68ec5103e83ba17f63 380 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 274 280 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 hmeg3_RS10375 af1f7a9e969afa68ec5103e83ba17f63 380 PIRSF PIRSF000138 1 380 4.9E-123 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 Pfam PF00672 HAMP domain 236 279 1.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 Pfam PF12729 Four helix bundle sensory module for signal transduction 30 197 5.5E-9 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 SMART SM00304 236 288 3.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 349 504 2.6E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 SMART SM00283 289 536 1.0E-70 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 212 232 2.4E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 464 493 2.4E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 387 414 2.4E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 310 339 2.4E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 416 445 2.4E-48 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 Gene3D G3DSA:1.10.287.950 343 540 4.0E-42 T 28-03-2018 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 Gene3D G3DSA:1.10.287.950 57 342 6.3E-12 T 28-03-2018 hmeg3_RS12470 2852d6111405f1a6204f830d2a170497 579 SUPERFAMILY SSF58104 256 537 1.26E-65 T 28-03-2018 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 TIGRFAM TIGR01083 nth: endonuclease III 4 194 6.3E-87 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 PIRSF PIRSF001435 1 210 4.7E-53 T 28-03-2018 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 Gene3D G3DSA:1.10.1670.10 118 214 3.9E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 SMART SM00478 38 185 3.3E-55 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 2.2E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 SUPERFAMILY SSF48150 2 208 5.02E-73 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 Gene3D G3DSA:1.10.340.30 18 117 3.2E-22 T 28-03-2018 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 SMART SM00525 186 206 1.3E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 169 6.6E-19 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.305 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 Pfam PF00633 Helix-hairpin-helix motif 99 127 1.0E-10 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 hmeg3_RS14610 f9e34183ff212b6195d8dbe81e2f7470 216 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 Pfam PF00672 HAMP domain 220 263 2.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 SMART SM00304 220 272 4.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 Pfam PF12729 Four helix bundle sensory module for signal transduction 13 189 2.0E-17 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 488 5.7E-47 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 SUPERFAMILY SSF58104 240 521 1.1E-65 T 28-03-2018 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 SMART SM00283 273 520 4.5E-79 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 Gene3D G3DSA:1.10.287.950 88 325 8.0E-15 T 28-03-2018 hmeg3_RS05405 fe1ab346a388e31e15ecbe82209161c4 567 Gene3D G3DSA:1.10.287.950 326 524 1.5E-43 T 28-03-2018 hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 Gene3D G3DSA:3.40.50.620 1 145 8.8E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 SUPERFAMILY SSF52402 152 273 1.34E-19 T 28-03-2018 hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 Pfam PF00582 Universal stress protein family 3 141 2.4E-8 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 Pfam PF00582 Universal stress protein family 152 272 2.5E-9 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 SUPERFAMILY SSF52402 1 141 8.2E-21 T 28-03-2018 hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 PRINTS PR01438 Universal stress protein signature 252 274 4.4E-11 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 PRINTS PR01438 Universal stress protein signature 234 246 4.4E-11 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 PRINTS PR01438 Universal stress protein signature 3 21 4.4E-11 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11450 35db5604a901b14a1cdbe449bad0259b 274 Gene3D G3DSA:3.40.50.620 146 274 4.1E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS23150 79516d075dca1ad5cdca85d080a6ca00 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 322 9.3E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23150 79516d075dca1ad5cdca85d080a6ca00 324 Gene3D G3DSA:1.10.3720.10 2 311 2.2E-43 T 28-03-2018 hmeg3_RS23150 79516d075dca1ad5cdca85d080a6ca00 324 SUPERFAMILY SSF161098 96 309 6.76E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS20245 e9f6767e695ebfa8ad67b1fdb8440c32 408 SUPERFAMILY SSF53474 98 404 4.02E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20245 e9f6767e695ebfa8ad67b1fdb8440c32 408 Gene3D G3DSA:3.40.50.1820 76 407 1.3E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20245 e9f6767e695ebfa8ad67b1fdb8440c32 408 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 5 405 1.3E-158 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase hmeg3_RS20245 e9f6767e695ebfa8ad67b1fdb8440c32 408 Pfam PF06850 PHB de-polymerase C-terminus 205 405 5.2E-89 T 28-03-2018 IPR009656 PHB de-polymerase, C-terminal hmeg3_RS20245 e9f6767e695ebfa8ad67b1fdb8440c32 408 PIRSF PIRSF020818 1 408 1.2E-174 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 SUPERFAMILY SSF55347 123 236 6.54E-33 T 28-03-2018 hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 Gene3D G3DSA:3.40.50.720 2 129 8.1E-11 T 28-03-2018 hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 SUPERFAMILY SSF51735 1 152 7.63E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 118 2.7E-21 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 Pfam PF01958 Domain of unknown function DUF108 167 254 2.4E-33 T 28-03-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 PIRSF PIRSF005227 1 266 2.3E-84 T 28-03-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 1 266 35.652 T 28-03-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 hmeg3_RS00135 4b04c4b32c62c03fdd42277d607a4933 266 Gene3D G3DSA:3.30.360.10 130 236 8.2E-38 T 28-03-2018 hmeg3_RS08680 b36dc4b1c05157e047213e03e6e684c7 258 SUPERFAMILY SSF53335 110 235 1.51E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS08680 b36dc4b1c05157e047213e03e6e684c7 258 Gene3D G3DSA:3.40.50.150 101 239 6.0E-13 T 28-03-2018 hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Gene3D G3DSA:3.40.50.300 2 220 5.0E-59 T 28-03-2018 hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Pfam PF03880 DbpA RNA binding domain 780 850 1.8E-19 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Pfam PF03880 DbpA RNA binding domain 628 698 7.3E-22 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Pfam PF03880 DbpA RNA binding domain 498 568 3.8E-22 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 SMART SM00487 26 224 9.7E-63 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 SMART SM00490 260 341 1.3E-33 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 SUPERFAMILY SSF52540 76 362 1.07E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Pfam PF00271 Helicase conserved C-terminal domain 233 341 1.7E-27 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Pfam PF00270 DEAD/DEAH box helicase 32 197 1.1E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 2 570 46.217 T 28-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 Gene3D G3DSA:3.40.50.300 221 375 1.2E-44 T 28-03-2018 hmeg3_RS00365 4a0c9ce82f3c39af7fa39761b96211ff 911 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site hmeg3_RS12665 fa15f10631bf9878dd375cf8381f068a 311 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 27 287 2.7E-72 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 hmeg3_RS12665 fa15f10631bf9878dd375cf8381f068a 311 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 25 290 1.7E-91 T 28-03-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 SMART SM00344 8 114 1.2E-31 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 8.0E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 SUPERFAMILY SSF54909 69 147 9.92E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 Gene3D G3DSA:1.10.10.10 3 59 6.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 Pfam PF01037 Lrp/AsnC ligand binding domain 74 144 1.3E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 Gene3D G3DSA:3.30.70.920 61 148 8.1E-18 T 28-03-2018 hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 SUPERFAMILY SSF46785 7 65 3.39E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.8E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.8E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS00050 fe9a5720e5949adb933b99c84c11f5d5 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.8E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 hmeg3_RS09495 f834b5baaa28bcf3a5cbca6757cb7a79 99 Gene3D G3DSA:3.40.1260.10 1 99 5.3E-12 T 28-03-2018 hmeg3_RS09495 f834b5baaa28bcf3a5cbca6757cb7a79 99 SUPERFAMILY SSF75169 4 98 5.83E-13 T 28-03-2018 IPR027396 DsrEFH-like hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 Gene3D G3DSA:3.40.50.1010 93 338 7.0E-44 T 28-03-2018 IPR029060 PIN domain-like hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 SMART SM00670 95 231 1.6E-12 T 28-03-2018 IPR002716 PIN domain hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 SUPERFAMILY SSF52540 117 209 1.65E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 SUPERFAMILY SSF52540 345 539 1.65E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 Pfam PF02562 PhoH-like protein 346 553 9.8E-54 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 Gene3D G3DSA:3.40.50.300 343 552 1.7E-20 T 28-03-2018 hmeg3_RS08415 41255e950132c1139a5d2dee4e3324b0 559 Pfam PF13638 PIN domain 97 243 2.1E-39 T 28-03-2018 IPR002716 PIN domain hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 SMART SM00382 37 184 5.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 Gene3D G3DSA:1.10.8.60 172 247 1.3E-17 T 28-03-2018 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 543 678 1.0E-9 T 28-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 SUPERFAMILY SSF48019 249 366 6.12E-30 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 SUPERFAMILY SSF52540 32 231 9.72E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 360 1.6E-127 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 237 365 8.3E-25 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 Pfam PF13177 DNA polymerase III, delta subunit 20 183 1.9E-37 T 28-03-2018 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 Gene3D G3DSA:3.40.50.300 1 171 4.1E-40 T 28-03-2018 hmeg3_RS17920 07a0696fc24232f0e3d0905a22cdf654 684 Gene3D G3DSA:1.20.272.10 248 367 1.0E-11 T 28-03-2018 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 SUPERFAMILY SSF47203 225 380 4.83E-62 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 SUPERFAMILY SSF56645 1 240 5.37E-81 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 Gene3D G3DSA:1.20.140.10 217 384 2.3E-62 T 28-03-2018 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 PIRSF PIRSF016578 4 385 3.5E-28 T 28-03-2018 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 Gene3D G3DSA:1.10.540.10 1 119 1.6E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 3.9E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 6.5E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 377 5.3E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 hmeg3_RS10795 d8d9178c4a562789beb84582955b5caa 386 Gene3D G3DSA:2.40.110.10 120 216 5.4E-36 T 28-03-2018 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 Gene3D G3DSA:3.40.50.2300 156 332 1.7E-35 T 28-03-2018 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 SUPERFAMILY SSF53822 25 380 8.75E-90 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 5.9E-11 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 283 296 5.9E-11 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 5.9E-11 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 5.9E-11 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 Gene3D G3DSA:3.40.50.2300 10 155 8.6E-29 T 28-03-2018 hmeg3_RS13690 7829f697b2d949111a9196501c1adb1d 383 Pfam PF13458 Periplasmic binding protein 25 371 2.0E-73 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS00815 c458f8a374d69282edaefc1023346706 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 294 1.7E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS00815 c458f8a374d69282edaefc1023346706 334 Gene3D G3DSA:1.10.3470.10 12 299 1.5E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS10505 b7334c927c26cb3525df89f6c879552f 220 Gene3D G3DSA:2.60.40.10 143 220 0.027 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS10505 b7334c927c26cb3525df89f6c879552f 220 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 10 126 3.3E-19 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 hmeg3_RS10505 b7334c927c26cb3525df89f6c879552f 220 SUPERFAMILY SSF49354 5 125 1.13E-18 T 28-03-2018 IPR008962 PapD-like hmeg3_RS10505 b7334c927c26cb3525df89f6c879552f 220 Gene3D G3DSA:2.60.40.10 9 127 4.0E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 134 144 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 123 134 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 144 155 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 109 166 1.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Pfam PF03466 LysR substrate binding domain 192 400 1.3E-32 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 SUPERFAMILY SSF46785 104 216 4.94E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Gene3D G3DSA:1.10.10.10 104 188 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Gene3D G3DSA:1.10.10.10 1 87 8.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 SUPERFAMILY SSF53850 195 404 1.09E-36 T 28-03-2018 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Gene3D G3DSA:3.40.190.10 284 372 3.4E-14 T 28-03-2018 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 Gene3D G3DSA:3.40.190.10 192 283 3.9E-20 T 28-03-2018 hmeg3_RS19380 b7a16ac46a1edec65e84fa098be62e07 414 SUPERFAMILY SSF46785 3 85 4.67E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09115 c4ae3d8e8755556ebe4082e18cbf2f91 347 SUPERFAMILY SSF52096 74 206 3.32E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS09115 c4ae3d8e8755556ebe4082e18cbf2f91 347 SUPERFAMILY SSF52096 235 295 3.32E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS09115 c4ae3d8e8755556ebe4082e18cbf2f91 347 Pfam PF01343 Peptidase family S49 162 303 1.8E-37 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 hmeg3_RS09115 c4ae3d8e8755556ebe4082e18cbf2f91 347 Gene3D G3DSA:3.90.226.10 93 297 1.7E-32 T 28-03-2018 hmeg3_RS17255 c7a95b7f639f856885609df9ac9e0edd 43 Pfam PF08085 Entericidin EcnA/B family 21 40 2.4E-8 T 28-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 hmeg3_RS19705 e5c88588c0fcad851179618ad28140c5 187 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 21 160 3.7E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 Pfam PF13609 Gram-negative porin 7 344 5.7E-50 T 28-03-2018 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 97 107 2.3E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 53 64 2.3E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 319 336 2.3E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 Gene3D G3DSA:2.40.160.10 9 371 4.0E-73 T 28-03-2018 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 SUPERFAMILY SSF56935 21 371 3.52E-79 T 28-03-2018 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 PRINTS PR00184 Neisseria sp. porin signature 316 340 2.4E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS10640 5c35a1179d02758cd8ce94491b0426af 371 PRINTS PR00184 Neisseria sp. porin signature 55 80 2.4E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 Gene3D G3DSA:3.30.565.10 309 459 3.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 SUPERFAMILY SSF55874 292 455 1.17E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 SMART SM00387 346 458 2.0E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 Gene3D G3DSA:1.10.287.130 227 299 5.4E-11 T 28-03-2018 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 455 1.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 2.9E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 SUPERFAMILY SSF47384 220 303 4.51E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 SMART SM00304 183 236 1.0E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 3.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 3.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 3.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 SMART SM00388 237 303 9.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 hmeg3_RS02110 36fbbcf25cfdc9dd6f7cd3eac521f9b8 459 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 5 455 6.2E-141 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 hmeg3_RS01495 8e68cd351089b4b3c7b131779929c751 98 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 38 3.6E-9 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain hmeg3_RS16845 b56cdcdd190f521a6c987c8c4abbe4b9 218 Pfam PF01713 Smr domain 129 209 1.3E-27 T 28-03-2018 IPR002625 Smr domain hmeg3_RS16845 b56cdcdd190f521a6c987c8c4abbe4b9 218 SMART SM00463 126 210 1.3E-19 T 28-03-2018 IPR002625 Smr domain hmeg3_RS16845 b56cdcdd190f521a6c987c8c4abbe4b9 218 SUPERFAMILY SSF160443 127 209 6.41E-21 T 28-03-2018 IPR002625 Smr domain hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 SUPERFAMILY SSF58104 253 519 1.96E-65 T 28-03-2018 hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 Gene3D G3DSA:1.10.287.950 179 322 1.1E-10 T 28-03-2018 hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 Gene3D G3DSA:1.10.287.950 323 522 2.1E-45 T 28-03-2018 hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 SMART SM00283 271 518 4.7E-81 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 486 2.6E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 188 2.9E-16 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS01705 6e794354a5b3c02c3d8ef8c2e67ed1d2 550 Gene3D G3DSA:1.20.120.30 22 178 2.7E-11 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 Gene3D G3DSA:2.40.50.100 70 284 1.5E-12 T 28-03-2018 hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 SUPERFAMILY SSF51230 72 113 5.1E-5 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 Gene3D G3DSA:2.40.50.100 285 425 2.2E-6 T 28-03-2018 hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 Pfam PF13533 Biotin-lipoyl like 76 112 1.4E-5 T 28-03-2018 hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 428 445 8.9E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 87 107 8.9E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 413 428 8.9E-7 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 hmeg3_RS10215 ca70ed0dc8ddf301ca1c1ab875755d0e 445 Pfam PF13437 HlyD family secretion protein 271 365 3.2E-9 T 28-03-2018 hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 106.321 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 Gene3D G3DSA:1.10.1270.20 175 248 1.3E-29 T 28-03-2018 hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 PIRSF PIRSF000386 1 247 1.1E-91 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 Gene3D G3DSA:3.40.1280.10 1 174 4.9E-70 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 225 2.7E-58 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 231 1.4E-90 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 hmeg3_RS16030 16f223a301b1f87ab0e3e28477427cef 248 SUPERFAMILY SSF75217 1 234 1.77E-93 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS07515 56ed1059fc1da8be412536372f8d7f52 337 Pfam PF00589 Phage integrase family 166 329 3.1E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS07515 56ed1059fc1da8be412536372f8d7f52 337 Gene3D G3DSA:1.10.443.10 166 337 1.9E-29 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS07515 56ed1059fc1da8be412536372f8d7f52 337 SUPERFAMILY SSF56349 60 334 8.48E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS07515 56ed1059fc1da8be412536372f8d7f52 337 Gene3D G3DSA:1.10.150.130 53 165 1.5E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 Pfam PF00106 short chain dehydrogenase 6 188 2.2E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 6.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 6.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 Gene3D G3DSA:3.40.50.720 4 264 7.8E-58 T 28-03-2018 hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS13540 2bc9eeddc475060f4a7f0019195e68c6 275 SUPERFAMILY SSF51735 5 249 3.57E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02905 b06802eff81f9b609ec39763a826f266 322 SUPERFAMILY SSF51735 1 279 2.0E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02905 b06802eff81f9b609ec39763a826f266 322 Gene3D G3DSA:3.40.50.720 3 315 1.2E-46 T 28-03-2018 hmeg3_RS02905 b06802eff81f9b609ec39763a826f266 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 218 6.9E-23 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS11240 830f3b9bc51d64e384a2527b3fc0f950 448 SUPERFAMILY SSF103473 40 440 1.57E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS11240 830f3b9bc51d64e384a2527b3fc0f950 448 Pfam PF07690 Major Facilitator Superfamily 139 409 2.5E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS11240 830f3b9bc51d64e384a2527b3fc0f950 448 Gene3D G3DSA:1.20.1250.20 42 241 9.2E-18 T 28-03-2018 hmeg3_RS11240 830f3b9bc51d64e384a2527b3fc0f950 448 Gene3D G3DSA:1.20.1250.20 255 441 3.7E-11 T 28-03-2018 hmeg3_RS11240 830f3b9bc51d64e384a2527b3fc0f950 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 320 337 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS11355 20d2d8c7ceddd47a3e72382ad825145a 195 Gene3D G3DSA:3.30.70.1070 1 162 9.7E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 SUPERFAMILY SSF58104 230 512 2.22E-76 T 28-03-2018 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 SMART SM00304 210 262 3.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 SMART SM00283 263 510 1.8E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 477 5.1E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 Gene3D G3DSA:1.20.120.30 23 184 8.7E-15 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 Gene3D G3DSA:1.10.287.950 323 514 5.1E-49 T 28-03-2018 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 Gene3D G3DSA:1.10.287.1060 240 322 0.016 T 28-03-2018 hmeg3_RS00780 9a3686bc31783b22bc6e2067c215aae0 561 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 182 7.6E-24 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS03040 4c25b8168c299c416b00cd955436336a 244 Gene3D G3DSA:3.40.50.1860 7 109 1.9E-4 T 28-03-2018 hmeg3_RS03040 4c25b8168c299c416b00cd955436336a 244 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 208 2.0E-17 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS03040 4c25b8168c299c416b00cd955436336a 244 Gene3D G3DSA:3.40.50.1860 110 201 2.1E-10 T 28-03-2018 hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 Gene3D G3DSA:1.10.10.10 14 85 7.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 Gene3D G3DSA:3.40.640.10 115 359 2.6E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 Pfam PF00155 Aminotransferase class I and II 113 434 2.6E-17 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 1.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 SMART SM00345 24 83 9.2E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 SUPERFAMILY SSF46785 17 91 8.36E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 SUPERFAMILY SSF53383 80 450 1.6E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS01750 a17b66011a08d355f70ae01073339c4d 460 Gene3D G3DSA:3.90.1150.10 360 452 2.8E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 SUPERFAMILY SSF46785 9 139 2.81E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 Pfam PF12727 PBP superfamily domain 139 325 8.6E-55 T 28-03-2018 IPR024370 PBP domain hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 Gene3D G3DSA:1.10.10.10 1 106 6.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 SUPERFAMILY SSF53850 121 339 2.36E-15 T 28-03-2018 hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 Gene3D G3DSA:3.40.190.10 107 215 4.7E-4 T 28-03-2018 hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 Gene3D G3DSA:3.40.190.10 216 292 5.3E-7 T 28-03-2018 hmeg3_RS16140 f975aca49dfb662867675f2b72ac90aa 355 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 82 1.2E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS02390 18c908463087754ade1d734161dcbe1e 886 Gene3D G3DSA:2.30.30.130 723 781 1.1E-6 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal hmeg3_RS02390 18c908463087754ade1d734161dcbe1e 886 Gene3D G3DSA:1.10.10.60 421 484 2.8E-8 T 28-03-2018 hmeg3_RS02390 18c908463087754ade1d734161dcbe1e 886 SUPERFAMILY SSF53098 506 691 2.43E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS02390 18c908463087754ade1d734161dcbe1e 886 Pfam PF00665 Integrase core domain 509 628 2.2E-13 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 hmeg3_RS02390 18c908463087754ade1d734161dcbe1e 886 Gene3D G3DSA:3.40.1350.10 21 167 2.2E-15 T 28-03-2018 hmeg3_RS02390 18c908463087754ade1d734161dcbe1e 886 Gene3D G3DSA:3.30.420.10 504 709 3.4E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 Gene3D G3DSA:1.10.10.10 2 71 2.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 Gene3D G3DSA:3.30.450.40 72 253 2.7E-34 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 SUPERFAMILY SSF55781 73 249 3.99E-35 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 SUPERFAMILY SSF46785 4 74 1.82E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 Pfam PF01614 Bacterial transcriptional regulator 127 247 1.2E-13 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 Pfam PF09339 IclR helix-turn-helix domain 5 54 1.3E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS01550 af156bc904de2498acbe9294a20837c2 261 SMART SM00346 2 92 1.3E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 SMART SM00304 215 267 3.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 SUPERFAMILY SSF58104 235 516 1.29E-75 T 28-03-2018 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 SMART SM00283 268 515 1.6E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 Gene3D G3DSA:1.10.287.950 324 519 7.4E-49 T 28-03-2018 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 Gene3D G3DSA:1.10.287.950 147 323 8.6E-25 T 28-03-2018 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 191 211 2.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 366 393 2.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 424 2.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 443 472 2.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 289 318 2.0E-58 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17315 278440db858a843a9e565474ff098347 543 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 191 3.4E-13 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS17315 278440db858a843a9e565474ff098347 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 481 2.1E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 2.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 2.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 2.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 Gene3D G3DSA:1.10.1660.10 1 59 4.6E-19 T 28-03-2018 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 Gene3D G3DSA:1.10.1660.10 60 153 5.5E-12 T 28-03-2018 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 Pfam PF13411 MerR HTH family regulatory protein 6 66 2.8E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 SMART SM00422 5 74 5.6E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 hmeg3_RS17550 badd67cbf72821b8c5a8d1422fa4285d 168 SUPERFAMILY SSF46955 5 121 1.76E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain hmeg3_RS10650 2971d09b4b4bfadb812709299d96aa32 91 Gene3D G3DSA:3.30.300.90 1 91 3.2E-22 T 28-03-2018 hmeg3_RS10650 2971d09b4b4bfadb812709299d96aa32 91 Pfam PF01722 BolA-like protein 13 88 5.3E-25 T 28-03-2018 IPR002634 BolA protein hmeg3_RS10650 2971d09b4b4bfadb812709299d96aa32 91 SUPERFAMILY SSF82657 1 90 3.4E-25 T 28-03-2018 IPR002634 BolA protein hmeg3_RS10650 2971d09b4b4bfadb812709299d96aa32 91 PIRSF PIRSF003113 1 91 1.2E-24 T 28-03-2018 IPR002634 BolA protein hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 468 575 3.4E-14 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Gene3D G3DSA:1.20.140.10 267 463 4.7E-41 T 28-03-2018 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 SUPERFAMILY SSF56645 40 273 2.09E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 34 1.4E-10 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 276 441 3.7E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 266 3.7E-19 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Gene3D G3DSA:2.40.110.10 160 266 1.7E-26 T 28-03-2018 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 SUPERFAMILY SSF47203 282 455 3.38E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Gene3D G3DSA:1.10.540.10 23 159 9.1E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS01080 717f206c4be373cecc9b4980c006fcf6 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 157 6.8E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 Gene3D G3DSA:1.10.10.10 3 84 6.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 SUPERFAMILY SSF46785 4 112 4.51E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 Gene3D G3DSA:3.40.190.10 89 178 7.0E-17 T 28-03-2018 hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 SUPERFAMILY SSF53850 91 298 1.09E-51 T 28-03-2018 hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 Gene3D G3DSA:3.40.190.10 179 264 5.9E-29 T 28-03-2018 hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 Pfam PF03466 LysR substrate binding domain 90 293 4.4E-50 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS15045 f3b96f2f25b2b3f14b623ad0366d0e6c 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 6.0E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12830 2e42a4cac796c7c3591c1fdcc3a21e1d 202 SUPERFAMILY SSF49464 118 176 9.02E-8 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain hmeg3_RS12830 2e42a4cac796c7c3591c1fdcc3a21e1d 202 SUPERFAMILY SSF49503 47 136 1.15E-13 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS12830 2e42a4cac796c7c3591c1fdcc3a21e1d 202 Gene3D G3DSA:2.60.40.10 14 199 1.8E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS09300 fd3fedb937c513db565dadf33c8f8475 234 SUPERFAMILY SSF55874 95 225 2.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS09300 fd3fedb937c513db565dadf33c8f8475 234 Pfam PF07730 Histidine kinase 21 88 3.2E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS09300 fd3fedb937c513db565dadf33c8f8475 234 Gene3D G3DSA:3.30.565.10 16 232 1.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03255 e243d0d6b6d2f306ee7e8b0ed24a6f5d 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 281 6.5E-30 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS03255 e243d0d6b6d2f306ee7e8b0ed24a6f5d 297 Gene3D G3DSA:1.10.3470.10 1 289 4.3E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS09160 5b67a835ddf8fbdc92caff35ded96f78 208 Pfam PF05433 Glycine zipper 2TM domain 121 160 1.9E-10 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 hmeg3_RS21665 a9acf289c4b037426590cd318f40683d 213 Pfam PF01161 Phosphatidylethanolamine-binding protein 32 205 8.1E-39 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein hmeg3_RS21665 a9acf289c4b037426590cd318f40683d 213 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 34 205 2.9E-24 T 28-03-2018 IPR005247 YbhB/YbcL hmeg3_RS21665 a9acf289c4b037426590cd318f40683d 213 SUPERFAMILY SSF49777 1 205 1.13E-40 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein hmeg3_RS21665 a9acf289c4b037426590cd318f40683d 213 Gene3D G3DSA:3.90.280.10 1 208 6.2E-51 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein hmeg3_RS10860 4b4bcf24efa74bf68b3bb47729ce8ca2 176 Gene3D G3DSA:3.40.50.850 2 176 1.6E-39 T 28-03-2018 hmeg3_RS10860 4b4bcf24efa74bf68b3bb47729ce8ca2 176 Pfam PF00857 Isochorismatase family 8 153 1.1E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS10860 4b4bcf24efa74bf68b3bb47729ce8ca2 176 SUPERFAMILY SSF52499 1 176 1.96E-46 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS18490 c0ac2c22122aefc5319cbbf7e0b98b50 144 Gene3D G3DSA:1.10.10.10 2 144 5.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18490 c0ac2c22122aefc5319cbbf7e0b98b50 144 Pfam PF01047 MarR family 30 77 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS18490 c0ac2c22122aefc5319cbbf7e0b98b50 144 SUPERFAMILY SSF46785 3 141 4.56E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18490 c0ac2c22122aefc5319cbbf7e0b98b50 144 SMART SM00347 23 126 4.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 260 3.7E-72 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 Gene3D G3DSA:2.120.10.30 3 285 7.1E-30 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 242 260 9.3E-25 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 9.3E-25 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 200 217 9.3E-25 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 92 113 9.3E-25 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 158 178 9.3E-25 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 135 157 9.3E-25 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS22080 725f725c0a9227abe91953d173783bd2 292 SUPERFAMILY SSF63829 10 289 9.81E-57 T 28-03-2018 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 Pfam PF01479 S4 domain 42 87 2.7E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 37 334 9.2E-81 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 SUPERFAMILY SSF55174 41 92 9.08E-7 T 28-03-2018 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 Gene3D G3DSA:3.10.290.10 29 99 5.7E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 SUPERFAMILY SSF55120 108 335 1.76E-63 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 Pfam PF00849 RNA pseudouridylate synthase 117 266 1.2E-30 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 SMART SM00363 42 101 3.1E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 156 170 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS09100 e8b8cb4a5abcf22fa6fba9039731c382 344 Gene3D G3DSA:3.30.2350.10 108 338 9.6E-67 T 28-03-2018 hmeg3_RS14415 5bdecf24869b7c9867d7169c805ea116 289 Gene3D G3DSA:1.10.3720.10 13 281 8.3E-38 T 28-03-2018 hmeg3_RS14415 5bdecf24869b7c9867d7169c805ea116 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 270 1.1E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14415 5bdecf24869b7c9867d7169c805ea116 289 SUPERFAMILY SSF161098 13 272 1.78E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 SUPERFAMILY SSF46894 137 216 2.62E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 Pfam PF00072 Response regulator receiver domain 9 121 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 Gene3D G3DSA:1.10.10.10 132 218 2.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 Gene3D G3DSA:3.40.50.2300 6 131 6.8E-35 T 28-03-2018 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 SUPERFAMILY SSF52172 6 139 7.97E-33 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 SMART SM00421 152 209 6.6E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 1.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 SMART SM00448 7 120 8.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS01620 0af91387b832a20d52415f39afc73890 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 SUPERFAMILY SSF55785 407 534 1.5E-26 T 28-03-2018 IPR000014 PAS domain hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Pfam PF00990 Diguanylate cyclase, GGDEF domain 547 705 2.1E-48 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Gene3D G3DSA:3.30.450.20 180 299 2.8E-15 T 28-03-2018 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Gene3D G3DSA:3.30.450.20 404 538 3.0E-27 T 28-03-2018 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Gene3D G3DSA:3.30.70.270 539 709 8.4E-57 T 28-03-2018 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Pfam PF00989 PAS fold 420 533 2.7E-19 T 28-03-2018 IPR013767 PAS fold GO:0006355 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 415 539 1.4E-27 T 28-03-2018 IPR000014 PAS domain hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Pfam PF02743 Cache domain 45 282 4.0E-19 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 SUPERFAMILY SSF55073 552 709 5.57E-49 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 Gene3D G3DSA:3.30.450.20 35 179 5.0E-20 T 28-03-2018 hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 543 708 5.8E-45 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 SMART SM00267 536 709 1.1E-61 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS06030 19702d6fa492422ed48845655f38c491 715 SMART SM00091 419 486 8.1E-13 T 28-03-2018 IPR000014 PAS domain hmeg3_RS12745 3b350c01ad182b10f3890cb353237957 245 Gene3D G3DSA:2.40.30.10 12 117 6.5E-26 T 28-03-2018 hmeg3_RS12745 3b350c01ad182b10f3890cb353237957 245 Gene3D G3DSA:3.40.50.80 118 244 2.3E-36 T 28-03-2018 hmeg3_RS12745 3b350c01ad182b10f3890cb353237957 245 SUPERFAMILY SSF63380 13 120 1.2E-14 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS12745 3b350c01ad182b10f3890cb353237957 245 Pfam PF08021 Siderophore-interacting FAD-binding domain 67 117 4.5E-11 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting hmeg3_RS12745 3b350c01ad182b10f3890cb353237957 245 Pfam PF04954 Siderophore-interacting protein 125 236 4.5E-32 T 28-03-2018 IPR007037 Siderophore-interacting protein hmeg3_RS01085 0754f4c5c6391790c666aa22d2d7bacc 191 Pfam PF11578 Protein of unknown function (DUF3237) 41 188 2.4E-42 T 28-03-2018 IPR020915 Uncharacterised protein family UPF0311 hmeg3_RS01085 0754f4c5c6391790c666aa22d2d7bacc 191 Gene3D G3DSA:2.40.160.20 32 191 1.3E-49 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS01085 0754f4c5c6391790c666aa22d2d7bacc 191 Hamap MF_00775 UPF0311 protein . 41 191 25.492 T 28-03-2018 IPR020915 Uncharacterised protein family UPF0311 hmeg3_RS12900 fb353a6d6b9b5391d5feb0adeb6a4b7b 281 SUPERFAMILY SSF51621 6 233 5.23E-61 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS12900 fb353a6d6b9b5391d5feb0adeb6a4b7b 281 Gene3D G3DSA:3.20.20.60 2 235 1.6E-46 T 28-03-2018 hmeg3_RS12900 fb353a6d6b9b5391d5feb0adeb6a4b7b 281 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 8 223 1.9E-34 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 hmeg3_RS12900 fb353a6d6b9b5391d5feb0adeb6a4b7b 281 PIRSF PIRSF015582 1 281 1.3E-76 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like hmeg3_RS05085 4d581c3086c8f3952ca908bb9fe841b4 447 Pfam PF07804 HipA-like C-terminal domain 204 376 3.5E-21 T 28-03-2018 IPR012893 HipA-like, C-terminal hmeg3_RS05085 4d581c3086c8f3952ca908bb9fe841b4 447 Gene3D G3DSA:1.10.10.10 14 264 0.095 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23650 ca186ca8b22b58896481a56b2a0df76f 181 Gene3D G3DSA:3.90.1340.10 1 56 1.2E-19 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS23650 ca186ca8b22b58896481a56b2a0df76f 181 SUPERFAMILY SSF88874 3 175 6.15E-39 T 28-03-2018 hmeg3_RS23650 ca186ca8b22b58896481a56b2a0df76f 181 Gene3D G3DSA:4.10.1070.10 57 163 5.0E-4 T 28-03-2018 hmeg3_RS23650 ca186ca8b22b58896481a56b2a0df76f 181 Pfam PF07484 Phage Tail Collar Domain 8 64 2.3E-22 T 28-03-2018 IPR011083 Phage tail collar domain hmeg3_RS21565 9431810d4063e34ca6854a2de3a4f9e4 346 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 45 297 7.6E-70 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS21565 9431810d4063e34ca6854a2de3a4f9e4 346 PIRSF PIRSF006470 14 343 1.1E-75 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS21565 9431810d4063e34ca6854a2de3a4f9e4 346 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 46 319 9.8E-76 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 SUPERFAMILY SSF53474 53 340 1.34E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 Gene3D G3DSA:3.40.50.1820 48 343 4.9E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 PRINTS PR00412 Epoxide hydrolase signature 146 159 5.2E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 PRINTS PR00412 Epoxide hydrolase signature 319 341 5.2E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 PRINTS PR00412 Epoxide hydrolase signature 98 113 5.2E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 PRINTS PR00412 Epoxide hydrolase signature 160 173 5.2E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 PRINTS PR00412 Epoxide hydrolase signature 78 96 5.2E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS06280 cae8e4b4a31bbd4525b729925c2e1017 344 Pfam PF00561 alpha/beta hydrolase fold 73 202 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 Gene3D G3DSA:1.10.10.60 8 69 1.2E-16 T 28-03-2018 hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 1.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 192 5.9E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 SUPERFAMILY SSF46689 15 79 5.49E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 SUPERFAMILY SSF48498 87 199 1.42E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 8.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS14955 1ad82ec233d9c38b56ad24fb88e3cd02 207 Gene3D G3DSA:1.10.357.10 70 200 8.1E-21 T 28-03-2018 hmeg3_RS03445 9ab1df85594dc076025e1f433a0f609d 211 Pfam PF05494 MlaC protein 35 197 1.8E-54 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC hmeg3_RS03445 9ab1df85594dc076025e1f433a0f609d 211 PIRSF PIRSF004649 1 210 1.3E-49 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC hmeg3_RS03445 9ab1df85594dc076025e1f433a0f609d 211 Gene3D G3DSA:1.10.10.640 163 209 1.1E-7 T 28-03-2018 hmeg3_RS03445 9ab1df85594dc076025e1f433a0f609d 211 Gene3D G3DSA:3.10.450.50 28 75 6.2E-5 T 28-03-2018 hmeg3_RS03445 9ab1df85594dc076025e1f433a0f609d 211 Gene3D G3DSA:3.10.450.50 76 162 4.3E-26 T 28-03-2018 hmeg3_RS11665 04b3418fe7d5e1bf22450ad9ce47a8f3 406 Pfam PF03929 PepSY-associated TM region 14 397 3.4E-60 T 28-03-2018 IPR005625 PepSY-associated TM protein hmeg3_RS03765 3c27f8c221681a2a66ef9dcbcd9248df 540 Gene3D G3DSA:3.90.76.10 77 209 3.6E-27 T 28-03-2018 hmeg3_RS03765 3c27f8c221681a2a66ef9dcbcd9248df 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 452 6.0E-63 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain hmeg3_RS03765 3c27f8c221681a2a66ef9dcbcd9248df 540 Gene3D G3DSA:3.40.190.10 210 307 1.5E-20 T 28-03-2018 hmeg3_RS03765 3c27f8c221681a2a66ef9dcbcd9248df 540 SUPERFAMILY SSF53850 62 530 3.08E-104 T 28-03-2018 hmeg3_RS03765 3c27f8c221681a2a66ef9dcbcd9248df 540 Gene3D G3DSA:3.10.105.10 308 505 1.4E-29 T 28-03-2018 hmeg3_RS03765 3c27f8c221681a2a66ef9dcbcd9248df 540 PIRSF PIRSF002741 28 538 1.4E-60 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 hmeg3_RS22820 9d76ad01024ea66548ecb1b6b02a1970 63 SUPERFAMILY SSF46561 1 60 3.4E-20 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22820 9d76ad01024ea66548ecb1b6b02a1970 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 3.0E-21 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22820 9d76ad01024ea66548ecb1b6b02a1970 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22820 9d76ad01024ea66548ecb1b6b02a1970 63 Gene3D G3DSA:1.10.287.310 1 63 6.9E-22 T 28-03-2018 hmeg3_RS22820 9d76ad01024ea66548ecb1b6b02a1970 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.287 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22820 9d76ad01024ea66548ecb1b6b02a1970 63 Pfam PF00831 Ribosomal L29 protein 4 60 8.8E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS21005 190fd9c8396465ba998423b25823b651 269 Gene3D G3DSA:3.40.190.10 26 117 1.1E-13 T 28-03-2018 hmeg3_RS21005 190fd9c8396465ba998423b25823b651 269 Gene3D G3DSA:3.40.190.10 118 216 1.1E-32 T 28-03-2018 hmeg3_RS21005 190fd9c8396465ba998423b25823b651 269 SUPERFAMILY SSF53850 28 255 1.83E-57 T 28-03-2018 hmeg3_RS21005 190fd9c8396465ba998423b25823b651 269 Pfam PF03180 NLPA lipoprotein 28 262 1.8E-61 T 28-03-2018 IPR004872 Lipoprotein NlpA family hmeg3_RS15245 78cf92b369cf69eb588e678142097b41 311 Pfam PF01497 Periplasmic binding protein 47 262 4.8E-25 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 hmeg3_RS15245 78cf92b369cf69eb588e678142097b41 311 SUPERFAMILY SSF53807 24 288 1.88E-59 T 28-03-2018 hmeg3_RS15245 78cf92b369cf69eb588e678142097b41 311 Gene3D G3DSA:3.40.50.1980 138 296 6.6E-29 T 28-03-2018 hmeg3_RS15245 78cf92b369cf69eb588e678142097b41 311 Gene3D G3DSA:3.40.50.1980 19 137 6.7E-28 T 28-03-2018 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 218 2.6E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 PIRSF PIRSF016578 236 385 1.8E-4 T 28-03-2018 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 PIRSF PIRSF016578 3 195 6.7E-9 T 28-03-2018 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 363 1.2E-31 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 SUPERFAMILY SSF47203 229 384 4.19E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 115 3.0E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 Gene3D G3DSA:1.20.140.10 220 386 5.0E-45 T 28-03-2018 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 SUPERFAMILY SSF56645 5 243 1.31E-61 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 Gene3D G3DSA:1.10.540.10 2 113 7.4E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 hmeg3_RS12910 9858e4568ee12856bfc5bb4b790776d3 386 Gene3D G3DSA:2.40.110.10 114 219 4.1E-28 T 28-03-2018 hmeg3_RS06285 bed8c4f98cd0d9bc175e26419360979d 174 SUPERFAMILY SSF52833 32 170 1.66E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS06285 bed8c4f98cd0d9bc175e26419360979d 174 Pfam PF08534 Redoxin 31 158 7.8E-16 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 hmeg3_RS06285 bed8c4f98cd0d9bc175e26419360979d 174 Gene3D G3DSA:3.40.30.10 7 174 3.2E-32 T 28-03-2018 hmeg3_RS19340 4280cd48c5b09ed00e70c318cb47b07f 375 Gene3D G3DSA:3.10.310.10 189 342 2.5E-52 T 28-03-2018 hmeg3_RS19340 4280cd48c5b09ed00e70c318cb47b07f 375 SUPERFAMILY SSF54506 179 374 2.88E-55 T 28-03-2018 hmeg3_RS19340 4280cd48c5b09ed00e70c318cb47b07f 375 Pfam PF04303 PrpF protein 11 370 1.5E-114 T 28-03-2018 IPR007400 PrpF protein hmeg3_RS19340 4280cd48c5b09ed00e70c318cb47b07f 375 Gene3D G3DSA:3.10.310.10 8 188 1.2E-76 T 28-03-2018 hmeg3_RS19340 4280cd48c5b09ed00e70c318cb47b07f 375 SUPERFAMILY SSF54506 8 175 1.1E-63 T 28-03-2018 hmeg3_RS08625 a9c1c591fe1416ae09237bb9017cbb65 255 Pfam PF01925 Sulfite exporter TauE/SafE 20 248 1.8E-27 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS18375 a9e8da996469af6b98e4e4461b20217f 705 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 7 675 1.5E-264 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 hmeg3_RS18375 a9e8da996469af6b98e4e4461b20217f 705 Pfam PF03030 Inorganic H+ pyrophosphatase 13 670 2.7E-271 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 hmeg3_RS18375 a9e8da996469af6b98e4e4461b20217f 705 PIRSF PIRSF001265 1 684 1.4E-265 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 hmeg3_RS18375 a9e8da996469af6b98e4e4461b20217f 705 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 2 676 25.441 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 hmeg3_RS24550 829988fb64748076316327683ff697f2 357 Gene3D G3DSA:3.40.190.10 25 152 3.9E-15 T 28-03-2018 hmeg3_RS24550 829988fb64748076316327683ff697f2 357 Pfam PF13416 Bacterial extracellular solute-binding protein 58 316 3.6E-30 T 28-03-2018 hmeg3_RS24550 829988fb64748076316327683ff697f2 357 SUPERFAMILY SSF53850 36 353 1.8E-51 T 28-03-2018 hmeg3_RS24550 829988fb64748076316327683ff697f2 357 Gene3D G3DSA:3.40.190.10 153 299 5.2E-26 T 28-03-2018 hmeg3_RS10545 3b2531516e8fd3ae66ca31073626a08c 284 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 259 281 1.3E-10 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS10545 3b2531516e8fd3ae66ca31073626a08c 284 Pfam PF00005 ABC transporter 49 210 1.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10545 3b2531516e8fd3ae66ca31073626a08c 284 SUPERFAMILY SSF52540 32 281 6.37E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10545 3b2531516e8fd3ae66ca31073626a08c 284 Gene3D G3DSA:3.40.50.300 20 284 3.6E-57 T 28-03-2018 hmeg3_RS10545 3b2531516e8fd3ae66ca31073626a08c 284 SMART SM00382 58 259 3.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 Pfam PF00005 ABC transporter 355 488 7.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 20 540 4.1E-94 T 28-03-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 SUPERFAMILY SSF52540 333 540 6.1E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 SUPERFAMILY SSF90123 21 303 1.57E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 Gene3D G3DSA:1.20.1560.10 8 309 2.0E-11 T 28-03-2018 hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 SMART SM00382 361 537 6.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS11725 2a80bb398ccb4e6bd8fbd5785839a76e 548 Gene3D G3DSA:3.40.50.300 332 546 7.0E-40 T 28-03-2018 hmeg3_RS07050 405748f6acb49a8f8fe170ff6ad4d5dd 262 SUPERFAMILY SSF53335 87 227 1.75E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS07050 405748f6acb49a8f8fe170ff6ad4d5dd 262 Pfam PF08241 Methyltransferase domain 84 135 2.6E-10 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS07050 405748f6acb49a8f8fe170ff6ad4d5dd 262 Gene3D G3DSA:3.40.50.150 56 210 2.2E-13 T 28-03-2018 hmeg3_RS15555 9ba6e469655bb532da5c6cfae90b658a 233 SUPERFAMILY SSF52540 48 160 9.67E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15555 9ba6e469655bb532da5c6cfae90b658a 233 Gene3D G3DSA:3.40.50.300 47 160 2.4E-26 T 28-03-2018 hmeg3_RS15555 9ba6e469655bb532da5c6cfae90b658a 233 PIRSF PIRSF037290 4 225 2.8E-70 T 28-03-2018 IPR017166 Uncharacterised conserved protein UCP037290 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 SMART SM00862 164 240 4.8E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 SUPERFAMILY SSF52172 10 135 1.1E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 SMART SM00448 15 125 3.9E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 Gene3D G3DSA:3.40.50.2300 3 135 3.9E-35 T 28-03-2018 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 Pfam PF00072 Response regulator receiver domain 17 124 1.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 240 9.1E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 SUPERFAMILY SSF46894 138 241 6.24E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06835 1b536a6fe3e9de537556e672260ec211 244 Gene3D G3DSA:1.10.10.10 136 244 9.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09470 c2c4c4216501af8c4f56c02c9f15fc42 187 Pfam PF02566 OsmC-like protein 64 167 1.2E-15 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS09470 c2c4c4216501af8c4f56c02c9f15fc42 187 Gene3D G3DSA:3.30.300.20 12 175 1.7E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS09470 c2c4c4216501af8c4f56c02c9f15fc42 187 SUPERFAMILY SSF82784 32 170 7.72E-30 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS14715 e9f047152b623605c61a40fd0ca2971c 178 Pfam PF07732 Multicopper oxidase 90 178 2.2E-33 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 hmeg3_RS14715 e9f047152b623605c61a40fd0ca2971c 178 SUPERFAMILY SSF49503 57 177 5.04E-34 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS14715 e9f047152b623605c61a40fd0ca2971c 178 Gene3D G3DSA:2.60.40.420 27 178 9.0E-31 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS04090 eb154bfce68dfeccbbce6bcd8cab5f99 169 SUPERFAMILY SSF50249 3 169 4.46E-61 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS04090 eb154bfce68dfeccbbce6bcd8cab5f99 169 Gene3D G3DSA:2.40.50.140 1 114 7.5E-45 T 28-03-2018 hmeg3_RS04090 eb154bfce68dfeccbbce6bcd8cab5f99 169 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 169 3.8E-57 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 hmeg3_RS04090 eb154bfce68dfeccbbce6bcd8cab5f99 169 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 38.531 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 hmeg3_RS04090 eb154bfce68dfeccbbce6bcd8cab5f99 169 Pfam PF00436 Single-strand binding protein family 4 108 1.7E-43 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 hmeg3_RS15760 8b7690e8592d6886e51493791777a7b0 691 Gene3D G3DSA:1.10.4150.10 96 276 7.5E-8 T 28-03-2018 IPR023225 Salmonella invasion protein A, chaperone-binding hmeg3_RS15760 8b7690e8592d6886e51493791777a7b0 691 Pfam PF09052 Salmonella invasion protein A 160 331 4.7E-7 T 28-03-2018 IPR015138 Salmonella invasion protein A hmeg3_RS15760 8b7690e8592d6886e51493791777a7b0 691 SUPERFAMILY SSF140746 102 270 1.83E-7 T 28-03-2018 IPR023225 Salmonella invasion protein A, chaperone-binding hmeg3_RS02015 2cae5d3396f646f594ccf655b8169aa1 64 Pfam PF11146 Protein of unknown function (DUF2905) 3 63 4.1E-18 T 28-03-2018 IPR021320 Protein of unknown function DUF2905 hmeg3_RS00360 bfed3b7e6061e937d6c7411230c18138 84 Pfam PF07369 Protein of unknown function (DUF1488) 7 70 1.5E-4 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 hmeg3_RS00360 bfed3b7e6061e937d6c7411230c18138 84 Gene3D G3DSA:3.30.160.140 3 74 5.3E-6 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 Gene3D G3DSA:3.40.190.10 172 253 2.5E-13 T 28-03-2018 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 Pfam PF03466 LysR substrate binding domain 87 276 1.7E-31 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 Gene3D G3DSA:1.10.10.10 1 86 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 Gene3D G3DSA:3.40.190.10 90 171 3.3E-16 T 28-03-2018 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 SUPERFAMILY SSF53850 88 276 9.91E-31 T 28-03-2018 hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 SUPERFAMILY SSF46785 1 109 1.54E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20630 0a7a2468e9207d8855449ca99144d08b 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05340 076c38d01929257bfacac0226bae2e6e 228 SUPERFAMILY SSF52499 4 207 1.57E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS05340 076c38d01929257bfacac0226bae2e6e 228 Pfam PF00857 Isochorismatase family 16 168 4.6E-28 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS05340 076c38d01929257bfacac0226bae2e6e 228 Gene3D G3DSA:3.40.50.850 2 211 5.0E-35 T 28-03-2018 hmeg3_RS10395 75975ee4843c8277b386e405899fe620 278 Gene3D G3DSA:1.10.3210.10 2 228 1.6E-31 T 28-03-2018 hmeg3_RS10395 75975ee4843c8277b386e405899fe620 278 SUPERFAMILY SSF109604 19 227 4.08E-35 T 28-03-2018 hmeg3_RS10395 75975ee4843c8277b386e405899fe620 278 Pfam PF08668 HDOD domain 22 165 3.9E-28 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 SMART SM00829 21 339 9.8E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 SUPERFAMILY SSF50129 7 146 1.93E-41 T 28-03-2018 IPR011032 GroES-like hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 Pfam PF00107 Zinc-binding dehydrogenase 161 289 7.6E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 SUPERFAMILY SSF50129 298 340 4.05E-7 T 28-03-2018 IPR011032 GroES-like hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 1.5E-39 T 28-03-2018 hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 Gene3D G3DSA:3.90.180.10 3 151 3.6E-34 T 28-03-2018 hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 Gene3D G3DSA:3.40.50.720 152 280 1.3E-29 T 28-03-2018 hmeg3_RS05975 98f83c4de26c21d24bbb1da61c392d3e 342 SUPERFAMILY SSF51735 126 307 3.42E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 99 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 SUPERFAMILY SSF103473 19 427 1.96E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 Pfam PF00083 Sugar (and other) transporter 24 230 1.9E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 Gene3D G3DSA:1.20.1250.20 17 232 4.9E-21 T 28-03-2018 hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 Pfam PF07690 Major Facilitator Superfamily 251 427 9.1E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS01865 4d68afda1d4823628458de2402dc5d67 431 Gene3D G3DSA:1.20.1250.20 233 430 7.2E-22 T 28-03-2018 hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 Pfam PF00106 short chain dehydrogenase 7 201 2.5E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 0.0066 T 28-03-2018 hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 SUPERFAMILY SSF51735 5 245 9.68E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 6.0E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 6.0E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 6.0E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.0E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.0E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS18370 2b6867652e8b80d163da8a6f8bd0ae5b 252 Gene3D G3DSA:3.40.50.720 1 252 8.1E-56 T 28-03-2018 hmeg3_RS13825 4e058c870e94f88f80d2d7e16f46c8a2 246 Pfam PF03746 LamB/YcsF family 3 235 7.4E-94 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF hmeg3_RS13825 4e058c870e94f88f80d2d7e16f46c8a2 246 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 240 42.529 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF hmeg3_RS13825 4e058c870e94f88f80d2d7e16f46c8a2 246 SUPERFAMILY SSF88713 1 243 1.04E-92 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS13825 4e058c870e94f88f80d2d7e16f46c8a2 246 Gene3D G3DSA:3.20.20.370 2 244 2.0E-97 T 28-03-2018 hmeg3_RS18835 7bcea2189e8a58239a1b40565636a8bb 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 3 155 7.8E-45 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18835 7bcea2189e8a58239a1b40565636a8bb 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 28.075 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18835 7bcea2189e8a58239a1b40565636a8bb 156 Gene3D G3DSA:3.40.1280.10 1 155 1.8E-52 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS18835 7bcea2189e8a58239a1b40565636a8bb 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 1.1E-49 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS18835 7bcea2189e8a58239a1b40565636a8bb 156 SUPERFAMILY SSF75217 1 154 1.27E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS18835 7bcea2189e8a58239a1b40565636a8bb 156 PIRSF PIRSF004505 1 155 6.4E-48 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 hmeg3_RS01150 9b218a6b6f90069aae773c6eac25f4ec 225 SUPERFAMILY SSF100950 2 222 3.7E-81 T 28-03-2018 hmeg3_RS01150 9b218a6b6f90069aae773c6eac25f4ec 225 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 2 219 4.7E-117 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01150 9b218a6b6f90069aae773c6eac25f4ec 225 SMART SM00882 6 219 3.7E-89 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01150 9b218a6b6f90069aae773c6eac25f4ec 225 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS01150 9b218a6b6f90069aae773c6eac25f4ec 225 Gene3D G3DSA:3.40.1080.10 2 225 2.1E-83 T 28-03-2018 hmeg3_RS01150 9b218a6b6f90069aae773c6eac25f4ec 225 Pfam PF01144 Coenzyme A transferase 6 218 2.0E-74 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 Gene3D G3DSA:1.25.40.10 553 673 1.5E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 SMART SM00028 628 661 1.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 SMART SM00028 560 593 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 Gene3D G3DSA:3.90.820.10 3 46 4.7E-8 T 28-03-2018 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 Gene3D G3DSA:1.25.40.10 113 487 0.13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 Pfam PF13181 Tetratricopeptide repeat 628 656 0.0062 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS09695 1c56e94232e83638867a4cee97753c2d 693 SUPERFAMILY SSF48452 553 660 1.86E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS11040 1c0c1b16aa0ab54378d2be0191fe419b 423 Gene3D G3DSA:3.40.190.10 140 418 2.8E-41 T 28-03-2018 hmeg3_RS11040 1c0c1b16aa0ab54378d2be0191fe419b 423 SUPERFAMILY SSF53850 23 417 4.43E-68 T 28-03-2018 hmeg3_RS11040 1c0c1b16aa0ab54378d2be0191fe419b 423 Gene3D G3DSA:3.40.190.10 23 134 0.0027 T 28-03-2018 hmeg3_RS11040 1c0c1b16aa0ab54378d2be0191fe419b 423 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 137 154 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 hmeg3_RS11040 1c0c1b16aa0ab54378d2be0191fe419b 423 Pfam PF01547 Bacterial extracellular solute-binding protein 42 331 5.9E-31 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 hmeg3_RS04980 21647b442bed3872613531eeb13b8c73 358 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 140 354 4.3E-66 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS04980 21647b442bed3872613531eeb13b8c73 358 Gene3D G3DSA:3.90.850.10 91 358 5.7E-76 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS04980 21647b442bed3872613531eeb13b8c73 358 SUPERFAMILY SSF56529 128 355 8.37E-72 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS21330 83438235c239b9629ced99b2a7dbad06 77 SUPERFAMILY SSF47336 5 73 1.44E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS21330 83438235c239b9629ced99b2a7dbad06 77 Gene3D G3DSA:1.10.1200.10 1 75 4.5E-5 T 28-03-2018 hmeg3_RS19350 4660604ca6caca5b324492dfdceb6d58 241 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 138 6.7E-20 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 hmeg3_RS19350 4660604ca6caca5b324492dfdceb6d58 241 Gene3D G3DSA:3.40.50.10320 2 240 6.8E-35 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 hmeg3_RS19350 4660604ca6caca5b324492dfdceb6d58 241 SUPERFAMILY SSF102588 7 239 2.35E-50 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 hmeg3_RS03885 9d34a988716b72d3e890f57c95ad991a 473 SUPERFAMILY SSF53187 10 205 1.74E-45 T 28-03-2018 hmeg3_RS03885 9d34a988716b72d3e890f57c95ad991a 473 SUPERFAMILY SSF53187 370 456 1.74E-45 T 28-03-2018 hmeg3_RS03885 9d34a988716b72d3e890f57c95ad991a 473 Gene3D G3DSA:3.40.630.10 12 208 7.3E-23 T 28-03-2018 hmeg3_RS03885 9d34a988716b72d3e890f57c95ad991a 473 Pfam PF07687 Peptidase dimerisation domain 203 355 1.1E-8 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS03885 9d34a988716b72d3e890f57c95ad991a 473 Pfam PF01546 Peptidase family M20/M25/M40 89 451 7.7E-19 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS03885 9d34a988716b72d3e890f57c95ad991a 473 Gene3D G3DSA:3.30.70.360 209 365 3.0E-30 T 28-03-2018 hmeg3_RS10125 76645a2b7c2b7ce6fcbf99def9adb5ac 179 SUPERFAMILY SSF53927 10 158 4.35E-58 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 hmeg3_RS10125 76645a2b7c2b7ce6fcbf99def9adb5ac 179 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 95 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 hmeg3_RS10125 76645a2b7c2b7ce6fcbf99def9adb5ac 179 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 13 154 49.441 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 hmeg3_RS10125 76645a2b7c2b7ce6fcbf99def9adb5ac 179 Gene3D G3DSA:3.40.140.10 1 164 1.8E-55 T 28-03-2018 hmeg3_RS10125 76645a2b7c2b7ce6fcbf99def9adb5ac 179 Pfam PF14437 MafB19-like deaminase 11 154 1.2E-35 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 hmeg3_RS19005 b0a3f73ae64b6e5c7567e7cb62dfe570 357 SUPERFAMILY SSF53822 31 345 1.18E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS19005 b0a3f73ae64b6e5c7567e7cb62dfe570 357 Gene3D G3DSA:3.40.50.2300 136 355 2.2E-27 T 28-03-2018 hmeg3_RS19005 b0a3f73ae64b6e5c7567e7cb62dfe570 357 Pfam PF13407 Periplasmic binding protein domain 33 309 3.2E-65 T 28-03-2018 IPR025997 Periplasmic binding protein hmeg3_RS19005 b0a3f73ae64b6e5c7567e7cb62dfe570 357 Gene3D G3DSA:3.40.50.2300 32 135 6.0E-17 T 28-03-2018 hmeg3_RS13335 50e9eefa4a5b17077186eca46e3d32b5 252 Pfam PF13531 Bacterial extracellular solute-binding protein 27 249 1.3E-50 T 28-03-2018 hmeg3_RS13335 50e9eefa4a5b17077186eca46e3d32b5 252 Gene3D G3DSA:3.40.190.10 121 213 1.8E-32 T 28-03-2018 hmeg3_RS13335 50e9eefa4a5b17077186eca46e3d32b5 252 SUPERFAMILY SSF53850 26 252 1.05E-65 T 28-03-2018 hmeg3_RS13335 50e9eefa4a5b17077186eca46e3d32b5 252 Gene3D G3DSA:3.40.190.10 21 120 4.1E-14 T 28-03-2018 hmeg3_RS13335 50e9eefa4a5b17077186eca46e3d32b5 252 PIRSF PIRSF004846 2 252 1.4E-72 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 hmeg3_RS13335 50e9eefa4a5b17077186eca46e3d32b5 252 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 32 248 8.6E-58 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 37 54 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 SUPERFAMILY SSF50891 2 161 1.2E-57 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 3 161 1.7E-48 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 Gene3D G3DSA:2.40.100.10 1 162 9.5E-52 T 28-03-2018 IPR029000 Cyclophilin-like domain hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 54 2.0E-14 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 16 31 2.0E-14 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 117 132 2.0E-14 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 hmeg3_RS08985 3e5641aea6011c2b3a14ce77b30c948c 162 PIRSF PIRSF001467 1 162 1.5E-29 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 hmeg3_RS15205 a536b4b0b75cfca5cba3a10b6bdc9fd6 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 18 96 3.8E-8 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS15205 a536b4b0b75cfca5cba3a10b6bdc9fd6 265 SUPERFAMILY SSF56784 13 261 6.95E-30 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS15205 a536b4b0b75cfca5cba3a10b6bdc9fd6 265 Gene3D G3DSA:3.40.50.1000 8 265 1.1E-23 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS15205 a536b4b0b75cfca5cba3a10b6bdc9fd6 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 229 3.3E-20 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 hmeg3_RS04555 2607173ecdac3263a8bfa22282d85636 334 SUPERFAMILY SSF56529 116 320 8.85E-22 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS04555 2607173ecdac3263a8bfa22282d85636 334 PIRSF PIRSF033905 1 333 2.5E-157 T 28-03-2018 IPR009645 Uncharacterised conserved protein GguC hmeg3_RS04555 2607173ecdac3263a8bfa22282d85636 334 Gene3D G3DSA:3.90.850.10 67 324 2.0E-22 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS05155 c61a61ba6eb2cecb79f14895e3c0df99 200 Gene3D G3DSA:3.30.700.10 17 196 5.2E-13 T 28-03-2018 hmeg3_RS05155 c61a61ba6eb2cecb79f14895e3c0df99 200 Pfam PF07963 Prokaryotic N-terminal methylation motif 15 35 5.4E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05155 c61a61ba6eb2cecb79f14895e3c0df99 200 Pfam PF12019 Type II transport protein GspH 53 172 3.0E-14 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 hmeg3_RS05155 c61a61ba6eb2cecb79f14895e3c0df99 200 SUPERFAMILY SSF54523 17 106 2.67E-16 T 28-03-2018 hmeg3_RS05155 c61a61ba6eb2cecb79f14895e3c0df99 200 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 36 2.2E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 Gene3D G3DSA:2.30.30.40 45 112 1.2E-34 T 28-03-2018 hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 Pfam PF08274 PhnA Zinc-Ribbon 3 32 1.8E-16 T 28-03-2018 IPR013987 PhnA protein, N-terminal hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 SUPERFAMILY SSF57783 3 37 2.04E-14 T 28-03-2018 hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 Gene3D G3DSA:2.20.25.10 2 40 1.2E-17 T 28-03-2018 hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 Pfam PF03831 PhnA domain 47 113 7.5E-32 T 28-03-2018 IPR013988 PhnA protein, C-terminal hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 112 3.9E-45 T 28-03-2018 IPR004624 PhnA protein hmeg3_RS00385 0018c187a8345cebbdd62ffdfbc9e6c2 113 SUPERFAMILY SSF82057 41 113 1.51E-27 T 28-03-2018 hmeg3_RS16220 1aacb1c77c93af51afa402ec445e3361 154 SUPERFAMILY SSF54637 18 142 6.85E-31 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS16220 1aacb1c77c93af51afa402ec445e3361 154 Gene3D G3DSA:3.10.129.10 13 144 1.6E-26 T 28-03-2018 hmeg3_RS16220 1aacb1c77c93af51afa402ec445e3361 154 Pfam PF13279 Thioesterase-like superfamily 28 133 2.2E-10 T 28-03-2018 hmeg3_RS11845 41b39b4c0a4c13d568e7bfa26dad3e70 376 Pfam PF03824 High-affinity nickel-transport protein 15 373 2.7E-39 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 hmeg3_RS18550 6266ed7077317791a144be87687d2108 287 Pfam PF07859 alpha/beta hydrolase fold 75 185 4.5E-20 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS18550 6266ed7077317791a144be87687d2108 287 SUPERFAMILY SSF53474 10 283 1.33E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS18550 6266ed7077317791a144be87687d2108 287 Gene3D G3DSA:3.40.50.1820 41 285 4.2E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02090 d715826143d4d2facf21d96f09a477af 107 Pfam PF09722 Protein of unknown function (DUF2384) 60 104 2.5E-10 T 28-03-2018 IPR024467 Domain of unknown function DUF2384 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 2.9E-7 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 PRINTS PR01713 Nucleotide sugar epimerase signature 257 272 2.9E-7 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 PRINTS PR01713 Nucleotide sugar epimerase signature 44 60 2.9E-7 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 PRINTS PR01713 Nucleotide sugar epimerase signature 233 248 2.9E-7 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 Gene3D G3DSA:3.90.25.10 195 343 3.3E-40 T 28-03-2018 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 SUPERFAMILY SSF51735 14 340 5.63E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 18 263 3.8E-56 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS01905 7b529bad9ddf59c99f55f34c971d715e 345 Gene3D G3DSA:3.40.50.720 18 194 3.0E-30 T 28-03-2018 hmeg3_RS16395 9e3c1dbc6a79813230bc07d0784f553b 269 Pfam PF00005 ABC transporter 43 179 2.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16395 9e3c1dbc6a79813230bc07d0784f553b 269 Gene3D G3DSA:3.40.50.300 16 253 4.6E-45 T 28-03-2018 hmeg3_RS16395 9e3c1dbc6a79813230bc07d0784f553b 269 SMART SM00382 42 225 9.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16395 9e3c1dbc6a79813230bc07d0784f553b 269 SUPERFAMILY SSF52540 24 230 2.5E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21115 e707a80c98152b131d1060b95907ddb9 432 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 427 3.8E-103 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 hmeg3_RS21115 e707a80c98152b131d1060b95907ddb9 432 SUPERFAMILY SSF56954 23 429 6.28E-88 T 28-03-2018 hmeg3_RS21115 e707a80c98152b131d1060b95907ddb9 432 Gene3D G3DSA:1.20.1600.10 15 422 1.7E-73 T 28-03-2018 hmeg3_RS21115 e707a80c98152b131d1060b95907ddb9 432 Pfam PF02321 Outer membrane efflux protein 25 202 2.4E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS21115 e707a80c98152b131d1060b95907ddb9 432 Pfam PF02321 Outer membrane efflux protein 226 411 1.9E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 Gene3D G3DSA:3.40.50.300 92 318 9.5E-68 T 28-03-2018 hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 96 339 1.1E-103 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 Gene3D G3DSA:3.30.300.130 1 91 6.9E-11 T 28-03-2018 IPR034904 Fe-S cluster assembly domain hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 Pfam PF01883 Iron-sulfur cluster assembly protein 6 78 5.7E-22 T 28-03-2018 IPR002744 MIP18 family-like hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 SUPERFAMILY SSF117916 1 85 8.83E-17 T 28-03-2018 IPR034904 Fe-S cluster assembly domain hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 SUPERFAMILY SSF52540 90 324 6.88E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 ProSitePatterns PS01215 Mrp family signature. 203 219 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 hmeg3_RS15180 b3c51e82bb84cdde7e372797527378f8 362 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 340 37.171 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein hmeg3_RS18695 31955702faf5c87daab1ac0d4526a9d6 352 SUPERFAMILY SSF103481 198 287 2.75E-5 T 28-03-2018 hmeg3_RS18695 31955702faf5c87daab1ac0d4526a9d6 352 Pfam PF00892 EamA-like transporter family 11 144 4.6E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS18695 31955702faf5c87daab1ac0d4526a9d6 352 SUPERFAMILY SSF103481 66 147 3.27E-10 T 28-03-2018 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 Pfam PF13432 Tetratricopeptide repeat 49 90 5.0E-5 T 28-03-2018 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 Pfam PF13432 Tetratricopeptide repeat 185 237 2.5E-6 T 28-03-2018 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 386 34.857 T 28-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 Gene3D G3DSA:1.25.40.10 118 173 0.0013 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 Gene3D G3DSA:1.25.40.10 32 117 4.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 SUPERFAMILY SSF81901 40 248 9.15E-15 T 28-03-2018 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 Gene3D G3DSA:1.25.40.10 175 317 3.6E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 SMART SM00028 180 213 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 SMART SM00028 214 247 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 SMART SM00028 37 69 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 SMART SM00028 108 141 430.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS17950 292492af7c50427e1d291e07fd19e86f 391 SMART SM00028 70 103 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 SMART SM00649 9 141 1.1E-85 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 SUPERFAMILY SSF46906 68 141 5.49E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.3E-64 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.702 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 SUPERFAMILY SSF54747 3 73 7.19E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 Gene3D G3DSA:3.30.1550.10 3 72 6.4E-33 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 5.1E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 9.8E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 28-03-2018 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 hmeg3_RS22925 02df63ef4eee009b90f63d3e0b9a596f 143 Gene3D G3DSA:1.10.10.250 73 141 8.5E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 hmeg3_RS15240 c4d61fc0f98e34610667b2d07e067deb 279 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 37.079 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 hmeg3_RS15240 c4d61fc0f98e34610667b2d07e067deb 279 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 5.9E-94 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 hmeg3_RS15240 c4d61fc0f98e34610667b2d07e067deb 279 SUPERFAMILY SSF52374 1 279 1.44E-95 T 28-03-2018 hmeg3_RS15240 c4d61fc0f98e34610667b2d07e067deb 279 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 278 3.9E-87 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 hmeg3_RS15240 c4d61fc0f98e34610667b2d07e067deb 279 Gene3D G3DSA:3.30.1300.10 172 279 4.8E-29 T 28-03-2018 hmeg3_RS15240 c4d61fc0f98e34610667b2d07e067deb 279 Gene3D G3DSA:3.40.50.620 1 170 1.7E-67 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PIRSF PIRSF000126 1 265 7.4E-79 T 28-03-2018 hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 Gene3D G3DSA:3.40.50.720 4 266 7.3E-49 T 28-03-2018 hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 SUPERFAMILY SSF51735 5 239 1.77E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23925 8d26cf0d8223c45b4ae81c8b2c3851fc 266 Pfam PF00106 short chain dehydrogenase 8 192 4.1E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS05390 6c642af9179cd88716113dbb84ee56f5 284 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 191 279 6.7E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05390 6c642af9179cd88716113dbb84ee56f5 284 SUPERFAMILY SSF55874 150 278 6.42E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05390 6c642af9179cd88716113dbb84ee56f5 284 Pfam PF07730 Histidine kinase 60 141 1.5E-5 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 hmeg3_RS05390 6c642af9179cd88716113dbb84ee56f5 284 SMART SM00387 185 281 7.3E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS05390 6c642af9179cd88716113dbb84ee56f5 284 Gene3D G3DSA:3.30.565.10 147 284 1.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS03700 d2eaf1fc76303a731ec4528695e9aba2 410 Pfam PF07690 Major Facilitator Superfamily 19 279 1.6E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS03700 d2eaf1fc76303a731ec4528695e9aba2 410 Gene3D G3DSA:1.20.1250.20 209 409 8.9E-25 T 28-03-2018 hmeg3_RS03700 d2eaf1fc76303a731ec4528695e9aba2 410 SUPERFAMILY SSF103473 8 399 9.68E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS03700 d2eaf1fc76303a731ec4528695e9aba2 410 Gene3D G3DSA:1.20.1250.20 2 206 8.7E-38 T 28-03-2018 hmeg3_RS23325 b3d4c0c9fc5e19c9ccde84767ca9afa8 330 Pfam PF13387 Domain of unknown function (DUF4105) 118 270 3.0E-45 T 28-03-2018 IPR025178 Domain of unknown function DUF4105 hmeg3_RS15670 336865cde78279ead58b29b4bf51c60c 138 Pfam PF01638 HxlR-like helix-turn-helix 40 127 1.1E-26 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS15670 336865cde78279ead58b29b4bf51c60c 138 SUPERFAMILY SSF46785 26 130 2.19E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15670 336865cde78279ead58b29b4bf51c60c 138 Gene3D G3DSA:1.10.10.10 37 138 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13740 df7e974c74c7c87dec4d50f58285cb45 214 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 163 2.5E-37 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS15775 4ec8719827a4afcd3c6d8e0140b94772 606 PRINTS PR01375 Salmonella/Shigella invasin protein B signature 175 191 2.2E-6 T 28-03-2018 IPR003895 Type III secretion system, invasin protein B GO:0005576|GO:0009405|GO:0016021 hmeg3_RS15775 4ec8719827a4afcd3c6d8e0140b94772 606 PRINTS PR01375 Salmonella/Shigella invasin protein B signature 466 486 2.2E-6 T 28-03-2018 IPR003895 Type III secretion system, invasin protein B GO:0005576|GO:0009405|GO:0016021 hmeg3_RS15775 4ec8719827a4afcd3c6d8e0140b94772 606 PRINTS PR01375 Salmonella/Shigella invasin protein B signature 308 327 2.2E-6 T 28-03-2018 IPR003895 Type III secretion system, invasin protein B GO:0005576|GO:0009405|GO:0016021 hmeg3_RS15775 4ec8719827a4afcd3c6d8e0140b94772 606 Gene3D G3DSA:1.20.5.340 273 509 0.073 T 28-03-2018 hmeg3_RS15775 4ec8719827a4afcd3c6d8e0140b94772 606 Pfam PF04888 Secretion system effector C (SseC) like family 267 598 9.3E-49 T 28-03-2018 IPR006972 Secretion system effector C, SseC-like GO:0009405 hmeg3_RS15775 4ec8719827a4afcd3c6d8e0140b94772 606 Gene3D G3DSA:1.20.5.50 115 245 3.6E-7 T 28-03-2018 hmeg3_RS14180 1e97863386cccc8483ee2464c2b58e1a 313 Gene3D G3DSA:1.10.3720.10 2 301 3.5E-47 T 28-03-2018 hmeg3_RS14180 1e97863386cccc8483ee2464c2b58e1a 313 SUPERFAMILY SSF161098 97 297 3.27E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14180 1e97863386cccc8483ee2464c2b58e1a 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.1E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS13195 e2fef5ff533025c5cd18685df3e3164f 118 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 10 116 3.8E-31 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 hmeg3_RS13195 e2fef5ff533025c5cd18685df3e3164f 118 Pfam PF13806 Rieske-like [2Fe-2S] domain 9 116 3.1E-38 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 hmeg3_RS13195 e2fef5ff533025c5cd18685df3e3164f 118 SUPERFAMILY SSF50022 9 117 8.8E-33 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS13195 e2fef5ff533025c5cd18685df3e3164f 118 Gene3D G3DSA:2.102.10.10 7 118 1.4E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 hmeg3_RS13615 3fd2206186894eacafec2843ae428bd1 160 Pfam PF00583 Acetyltransferase (GNAT) family 47 146 5.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS13615 3fd2206186894eacafec2843ae428bd1 160 SUPERFAMILY SSF55729 12 155 2.06E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS13615 3fd2206186894eacafec2843ae428bd1 160 Gene3D G3DSA:3.40.630.30 10 157 1.1E-23 T 28-03-2018 hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 252 3.4E-55 T 28-03-2018 hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 SUPERFAMILY SSF51735 11 253 9.25E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 5.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16525 395ca53caca7006c3f3afbe4bf6ebfb4 255 Gene3D G3DSA:3.40.50.720 3 253 2.7E-63 T 28-03-2018 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 Pfam PF00672 HAMP domain 210 258 2.0E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 175 1.1E-14 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 2.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 2.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 2.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 2.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 2.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 Gene3D G3DSA:1.10.287.950 318 512 3.7E-47 T 28-03-2018 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 Gene3D G3DSA:1.10.287.950 83 317 2.3E-20 T 28-03-2018 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 SMART SM00283 263 510 4.5E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 SUPERFAMILY SSF58104 230 511 6.28E-75 T 28-03-2018 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 SMART SM00304 210 262 2.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS24395 66af6e520d214b498a97461f5f92b583 512 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 476 7.5E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS17685 8a2aae333a4f43238a5bc6da3e9981a6 253 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 70 225 9.1E-34 T 28-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 Gene3D G3DSA:3.30.2350.10 73 248 1.4E-35 T 28-03-2018 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 SUPERFAMILY SSF55174 6 80 3.4E-15 T 28-03-2018 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 SUPERFAMILY SSF55120 66 246 4.48E-35 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 Pfam PF01479 S4 domain 5 50 1.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 Pfam PF00849 RNA pseudouridylate synthase 67 212 1.2E-11 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 SMART SM00363 5 70 2.0E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 85 243 8.3E-37 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS09920 e94012123f3642557c3eec05cc27d68b 248 Gene3D G3DSA:3.10.290.10 1 72 1.7E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS11930 049dbd9f6702e558676ceabaf32dabdb 198 SUPERFAMILY SSF48317 3 166 1.44E-29 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11930 049dbd9f6702e558676ceabaf32dabdb 198 Pfam PF01569 PAP2 superfamily 59 166 2.4E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11930 049dbd9f6702e558676ceabaf32dabdb 198 Gene3D G3DSA:1.20.144.10 10 172 2.9E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS11930 049dbd9f6702e558676ceabaf32dabdb 198 SMART SM00014 52 165 2.7E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase hmeg3_RS04540 f7602e4926448997a56c29c82f4f9fd3 244 SUPERFAMILY SSF52540 4 236 2.35E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04540 f7602e4926448997a56c29c82f4f9fd3 244 Gene3D G3DSA:3.40.50.300 1 243 5.3E-76 T 28-03-2018 hmeg3_RS04540 f7602e4926448997a56c29c82f4f9fd3 244 PIRSF PIRSF039085 1 244 1.7E-102 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 hmeg3_RS04540 f7602e4926448997a56c29c82f4f9fd3 244 SMART SM00382 29 217 2.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04540 f7602e4926448997a56c29c82f4f9fd3 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS04540 f7602e4926448997a56c29c82f4f9fd3 244 Pfam PF00005 ABC transporter 20 169 1.6E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21110 077a2f759130d69fb7fa6de6ed8cc94c 107 Pfam PF00581 Rhodanese-like domain 9 98 3.2E-15 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS21110 077a2f759130d69fb7fa6de6ed8cc94c 107 SMART SM00450 5 102 3.5E-18 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS21110 077a2f759130d69fb7fa6de6ed8cc94c 107 Gene3D G3DSA:3.40.250.10 1 107 2.4E-26 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS21110 077a2f759130d69fb7fa6de6ed8cc94c 107 SUPERFAMILY SSF52821 2 105 2.49E-30 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS02405 c4c06daeede844fd15be44f6dc2cf6fc 391 Gene3D G3DSA:3.40.50.300 19 216 4.2E-8 T 28-03-2018 hmeg3_RS02405 c4c06daeede844fd15be44f6dc2cf6fc 391 Pfam PF13191 AAA ATPase domain 19 202 2.6E-12 T 28-03-2018 hmeg3_RS02405 c4c06daeede844fd15be44f6dc2cf6fc 391 SUPERFAMILY SSF52540 6 299 5.74E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 Gene3D G3DSA:1.25.40.20 29 137 1.4E-21 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 Gene3D G3DSA:1.25.40.20 138 221 3.0E-24 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 Pfam PF12796 Ankyrin repeats (3 copies) 134 217 1.0E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 Pfam PF12796 Ankyrin repeats (3 copies) 48 128 2.7E-9 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 SUPERFAMILY SSF48403 38 217 1.37E-39 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 SMART SM00248 129 158 0.0046 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 SMART SM00248 99 128 2.1E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 SMART SM00248 196 225 1100.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 SMART SM00248 65 95 1400.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 SMART SM00248 163 192 0.048 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 PRINTS PR01415 Ankyrin repeat signature 130 145 6.8E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS10370 2e5c6a81ae65e9e5749eca2a8d23313c 230 PRINTS PR01415 Ankyrin repeat signature 179 193 6.8E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 Gene3D G3DSA:1.10.240.10 221 343 3.4E-30 T 28-03-2018 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 29 38 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 Gene3D G3DSA:3.40.50.620 19 220 5.7E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 Pfam PF00579 tRNA synthetases class I (W and Y) 19 302 2.2E-53 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 19 347 1.7E-74 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 84 103 7.9E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 214 224 7.9E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 33 49 7.9E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 162 183 7.9E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 hmeg3_RS15990 0a5314585b8a35c4496c00e3a67b09f9 350 SUPERFAMILY SSF52374 22 347 3.19E-77 T 28-03-2018 hmeg3_RS13390 a6d93402c7dbf3c9ac8bb5254fff428a 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 115 3.2E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 hmeg3_RS13390 a6d93402c7dbf3c9ac8bb5254fff428a 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.944 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 hmeg3_RS13390 a6d93402c7dbf3c9ac8bb5254fff428a 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 116 4.5E-27 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 Gene3D G3DSA:2.40.160.10 18 368 8.5E-60 T 28-03-2018 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 65 76 1.0E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 165 176 1.0E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 314 331 1.0E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 109 119 1.0E-8 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00184 Neisseria sp. porin signature 67 92 8.0E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00184 Neisseria sp. porin signature 164 181 8.0E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 PRINTS PR00184 Neisseria sp. porin signature 311 335 8.0E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 Pfam PF13609 Gram-negative porin 15 338 1.6E-49 T 28-03-2018 hmeg3_RS19160 eee6f67ca55da37eb617bcbffd0fd2d9 368 SUPERFAMILY SSF56935 30 368 2.24E-70 T 28-03-2018 hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 Gene3D G3DSA:3.40.50.620 1 145 2.6E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 Pfam PF00582 Universal stress protein family 1 145 7.2E-33 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 SUPERFAMILY SSF52402 1 145 9.21E-37 T 28-03-2018 hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 PIRSF PIRSF006276 1 145 2.3E-17 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 PRINTS PR01438 Universal stress protein signature 2 20 1.5E-17 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 PRINTS PR01438 Universal stress protein signature 123 145 1.5E-17 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS04475 1f5229b8b4262476bf46e3946e4373df 145 PRINTS PR01438 Universal stress protein signature 105 117 1.5E-17 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS20585 4f48537eff9c39f6f63ba97d038ce37d 476 SUPERFAMILY SSF103473 16 205 1.05E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS20585 4f48537eff9c39f6f63ba97d038ce37d 476 SUPERFAMILY SSF103473 251 467 1.05E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS20585 4f48537eff9c39f6f63ba97d038ce37d 476 Gene3D G3DSA:1.20.1250.20 254 476 2.8E-29 T 28-03-2018 hmeg3_RS20585 4f48537eff9c39f6f63ba97d038ce37d 476 Gene3D G3DSA:1.20.1250.20 10 200 3.0E-26 T 28-03-2018 hmeg3_RS20585 4f48537eff9c39f6f63ba97d038ce37d 476 Pfam PF07690 Major Facilitator Superfamily 22 412 3.3E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18480 412c0dc8a105eabb7074f105f71e8d31 343 SUPERFAMILY SSF53474 71 341 1.42E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS18480 412c0dc8a105eabb7074f105f71e8d31 343 Gene3D G3DSA:3.40.50.1820 12 343 7.7E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS18480 412c0dc8a105eabb7074f105f71e8d31 343 Pfam PF07859 alpha/beta hydrolase fold 107 315 1.0E-72 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS12555 e331d21e1316b7690d36ea9e2cc9160f 303 SUPERFAMILY SSF103481 191 297 3.4E-11 T 28-03-2018 hmeg3_RS12555 e331d21e1316b7690d36ea9e2cc9160f 303 SUPERFAMILY SSF103481 45 143 6.41E-13 T 28-03-2018 hmeg3_RS12555 e331d21e1316b7690d36ea9e2cc9160f 303 Pfam PF00892 EamA-like transporter family 158 290 6.4E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS12555 e331d21e1316b7690d36ea9e2cc9160f 303 Pfam PF00892 EamA-like transporter family 11 143 2.0E-23 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS19135 cdff245caf1f809b8d3e4ecc9bb84fcb 286 SUPERFAMILY SSF161098 6 279 5.23E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19135 cdff245caf1f809b8d3e4ecc9bb84fcb 286 Gene3D G3DSA:1.10.3720.10 10 285 4.5E-38 T 28-03-2018 hmeg3_RS19135 cdff245caf1f809b8d3e4ecc9bb84fcb 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 1.1E-7 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21250 a2de92e871d0aae9c170fc97868031af 162 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 142 8.1E-9 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS21250 a2de92e871d0aae9c170fc97868031af 162 Gene3D G3DSA:2.160.10.10 1 158 1.1E-32 T 28-03-2018 hmeg3_RS21250 a2de92e871d0aae9c170fc97868031af 162 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 48 80 0.21 T 28-03-2018 IPR001451 Hexapeptide repeat hmeg3_RS21250 a2de92e871d0aae9c170fc97868031af 162 SUPERFAMILY SSF51161 20 161 1.29E-31 T 28-03-2018 IPR011004 Trimeric LpxA-like hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 SUPERFAMILY SSF46785 11 92 1.52E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 Gene3D G3DSA:3.40.190.10 182 271 1.0E-25 T 28-03-2018 hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 2.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 Gene3D G3DSA:3.40.190.10 96 181 4.0E-11 T 28-03-2018 hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 Gene3D G3DSA:1.10.10.10 2 94 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 SUPERFAMILY SSF53850 97 300 1.65E-38 T 28-03-2018 hmeg3_RS16145 9126686e870b33897214bf13b338cf5e 304 Pfam PF03466 LysR substrate binding domain 96 299 4.1E-37 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS06105 645db12a0f7ddcbbf0693f219daa624d 242 Gene3D G3DSA:3.40.50.1860 115 212 6.2E-5 T 28-03-2018 hmeg3_RS06105 645db12a0f7ddcbbf0693f219daa624d 242 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 219 1.4E-8 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 hmeg3_RS06105 645db12a0f7ddcbbf0693f219daa624d 242 PIRSF PIRSF015736 1 242 1.4E-61 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase hmeg3_RS18705 2ee810222e8dab1dd185e4387a37a32c 100 Pfam PF03795 YCII-related domain 1 86 2.9E-7 T 28-03-2018 IPR005545 YCII-related hmeg3_RS18705 2ee810222e8dab1dd185e4387a37a32c 100 SUPERFAMILY SSF54909 1 88 3.49E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS18705 2ee810222e8dab1dd185e4387a37a32c 100 Gene3D G3DSA:3.30.70.1060 1 89 1.3E-16 T 28-03-2018 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 Pfam PF00005 ABC transporter 394 544 5.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 SUPERFAMILY SSF90123 37 348 2.49E-22 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 Gene3D G3DSA:3.40.50.300 363 608 5.7E-69 T 28-03-2018 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 ProSitePatterns PS00211 ABC transporters family signature. 516 530 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 SUPERFAMILY SSF52540 372 604 3.69E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 Gene3D G3DSA:1.20.1560.10 12 362 3.8E-21 T 28-03-2018 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 Pfam PF00664 ABC transporter transmembrane region 82 303 1.5E-11 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 hmeg3_RS21230 3357faecc53f7ac360f85a86af074192 608 SMART SM00382 403 589 4.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 23 48 2.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 304 333 2.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 458 487 2.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 408 2.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 439 2.8E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 Pfam PF12729 Four helix bundle sensory module for signal transduction 14 196 1.3E-15 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 498 9.2E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 SUPERFAMILY SSF58104 265 531 2.75E-71 T 28-03-2018 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 Gene3D G3DSA:1.10.287.950 94 337 4.6E-17 T 28-03-2018 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 Gene3D G3DSA:1.10.287.950 338 534 7.0E-49 T 28-03-2018 hmeg3_RS01385 53b6e7d1085b1c43dcf28f2a69fe3c1d 571 SMART SM00283 283 530 2.7E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS04480 69ad6a82143d02efcb2111c17b88e8fc 258 Gene3D G3DSA:3.90.226.10 2 218 9.0E-76 T 28-03-2018 hmeg3_RS04480 69ad6a82143d02efcb2111c17b88e8fc 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 258 1.8E-84 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS04480 69ad6a82143d02efcb2111c17b88e8fc 258 Gene3D G3DSA:1.10.12.10 219 256 3.1E-22 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS04480 69ad6a82143d02efcb2111c17b88e8fc 258 SUPERFAMILY SSF52096 1 257 1.17E-92 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS04480 69ad6a82143d02efcb2111c17b88e8fc 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 151 3.5E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 SUPERFAMILY SSF88659 92 154 9.16E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 Pfam PF04542 Sigma-70 region 2 9 70 6.7E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 Pfam PF08281 Sigma-70, region 4 99 149 2.1E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 SUPERFAMILY SSF88946 8 85 1.06E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 Gene3D G3DSA:1.10.10.10 87 162 6.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12805 5d3c6673bec74eb8aa562e362444e05a 166 Gene3D G3DSA:1.10.1740.10 5 72 7.1E-18 T 28-03-2018 hmeg3_RS14385 8979327d8d149a11f881f63a19b79ac2 309 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 35 294 8.6E-126 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 hmeg3_RS14385 8979327d8d149a11f881f63a19b79ac2 309 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 38 292 4.3E-97 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 hmeg3_RS14385 8979327d8d149a11f881f63a19b79ac2 309 Gene3D G3DSA:1.10.3720.10 35 299 3.9E-41 T 28-03-2018 hmeg3_RS14385 8979327d8d149a11f881f63a19b79ac2 309 SUPERFAMILY SSF161098 34 285 3.46E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14385 8979327d8d149a11f881f63a19b79ac2 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 290 5.1E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23535 ae421a6359d8409cace6234f09f08718 253 SUPERFAMILY SSF161098 24 211 2.75E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23535 ae421a6359d8409cace6234f09f08718 253 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 26 119 4.5E-21 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS23535 ae421a6359d8409cace6234f09f08718 253 Gene3D G3DSA:1.10.3720.10 6 231 6.7E-43 T 28-03-2018 hmeg3_RS23535 ae421a6359d8409cace6234f09f08718 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 226 7.6E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS13305 e89aa98a707a399d02eb0cce859f383c 295 Gene3D G3DSA:3.40.50.1380 16 157 1.2E-11 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS13305 e89aa98a707a399d02eb0cce859f383c 295 Gene3D G3DSA:3.40.50.1380 158 294 1.8E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS13305 e89aa98a707a399d02eb0cce859f383c 295 SUPERFAMILY SSF52335 155 269 2.29E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS13305 e89aa98a707a399d02eb0cce859f383c 295 SUPERFAMILY SSF52335 18 139 8.47E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain hmeg3_RS13305 e89aa98a707a399d02eb0cce859f383c 295 ProSitePatterns PS01335 Methylglyoxal synthase active site. 222 230 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 hmeg3_RS02575 550e7fb499d069bb71fe18f01430411c 640 Gene3D G3DSA:3.40.50.300 51 357 1.6E-12 T 28-03-2018 hmeg3_RS02575 550e7fb499d069bb71fe18f01430411c 640 SUPERFAMILY SSF52540 75 343 1.09E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS02575 550e7fb499d069bb71fe18f01430411c 640 Pfam PF08298 PrkA AAA domain 20 376 1.9E-171 T 28-03-2018 IPR013153 PrkA AAA domain hmeg3_RS02575 550e7fb499d069bb71fe18f01430411c 640 PIRSF PIRSF000549 1 640 4.8E-290 T 28-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 hmeg3_RS02575 550e7fb499d069bb71fe18f01430411c 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 378 632 1.7E-73 T 28-03-2018 IPR010650 PrkA C-terminal domain hmeg3_RS02575 550e7fb499d069bb71fe18f01430411c 640 SMART SM00763 19 376 9.4E-210 T 28-03-2018 IPR013153 PrkA AAA domain hmeg3_RS14125 7b639e51cc582db73959d6bbb629b2d1 335 Pfam PF02424 ApbE family 30 313 1.4E-81 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 hmeg3_RS14125 7b639e51cc582db73959d6bbb629b2d1 335 SUPERFAMILY SSF143631 24 333 1.44E-96 T 28-03-2018 IPR003374 ApbE-like domain hmeg3_RS14125 7b639e51cc582db73959d6bbb629b2d1 335 PIRSF PIRSF006268 15 334 2.9E-89 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 hmeg3_RS14125 7b639e51cc582db73959d6bbb629b2d1 335 Gene3D G3DSA:3.10.520.10 32 323 1.4E-53 T 28-03-2018 hmeg3_RS21355 d9edcf0bde1af2f141c331cf1e32d3bf 299 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 10 294 1.1E-151 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 hmeg3_RS21355 d9edcf0bde1af2f141c331cf1e32d3bf 299 SUPERFAMILY SSF53448 9 295 3.83E-89 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21355 d9edcf0bde1af2f141c331cf1e32d3bf 299 Gene3D G3DSA:3.90.550.10 10 298 3.1E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21355 d9edcf0bde1af2f141c331cf1e32d3bf 299 Pfam PF00483 Nucleotidyl transferase 10 245 3.4E-67 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS03400 4b5d053d644923ce8cc2388bb9a79104 306 Pfam PF00892 EamA-like transporter family 23 147 1.2E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS03400 4b5d053d644923ce8cc2388bb9a79104 306 SUPERFAMILY SSF103481 203 296 2.62E-5 T 28-03-2018 hmeg3_RS03400 4b5d053d644923ce8cc2388bb9a79104 306 SUPERFAMILY SSF103481 56 150 1.26E-10 T 28-03-2018 hmeg3_RS06825 13309f613fa97d0c4a4645aeabe4e0a5 486 PIRSF PIRSF004919 24 486 2.8E-135 T 28-03-2018 IPR025502 TldD hmeg3_RS06825 13309f613fa97d0c4a4645aeabe4e0a5 486 SUPERFAMILY SSF111283 33 485 4.32E-130 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 hmeg3_RS06825 13309f613fa97d0c4a4645aeabe4e0a5 486 Pfam PF01523 Putative modulator of DNA gyrase 43 337 1.1E-70 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 hmeg3_RS06825 13309f613fa97d0c4a4645aeabe4e0a5 486 Gene3D G3DSA:3.30.2290.10 26 240 2.4E-52 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 SUPERFAMILY SSF103473 8 200 2.49E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 SUPERFAMILY SSF103473 453 479 2.49E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 SUPERFAMILY SSF103473 244 414 2.49E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 Gene3D G3DSA:1.20.1250.20 247 491 3.5E-32 T 28-03-2018 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 ProSitePatterns PS00217 Sugar transport proteins signature 2. 361 386 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 Pfam PF07690 Major Facilitator Superfamily 18 405 3.9E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 Gene3D G3DSA:1.20.1250.20 1 194 2.4E-37 T 28-03-2018 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 74 96 3.1E-7 T 28-03-2018 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 3.1E-7 T 28-03-2018 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 3.1E-7 T 28-03-2018 hmeg3_RS01675 4ab44b375634a11982da2e5e9248e7a2 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 3.1E-7 T 28-03-2018 hmeg3_RS07165 378a5aa278dd5f6b183725c206cb61e9 166 Pfam PF04536 TPM domain 20 143 2.6E-11 T 28-03-2018 IPR007621 TPM domain hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 SMART SM00138 17 280 7.5E-30 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 SUPERFAMILY SSF53335 84 262 3.42E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 Gene3D G3DSA:1.10.155.10 14 81 3.1E-6 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 Gene3D G3DSA:3.40.50.150 82 282 1.0E-33 T 28-03-2018 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 Pfam PF01739 CheR methyltransferase, SAM binding domain 84 269 5.6E-38 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 SUPERFAMILY SSF47757 18 82 6.15E-5 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 PRINTS PR00996 Glutamate methyltransferase family signature 144 160 1.8E-23 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 PRINTS PR00996 Glutamate methyltransferase family signature 237 260 1.8E-23 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 PRINTS PR00996 Glutamate methyltransferase family signature 76 88 1.8E-23 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 PRINTS PR00996 Glutamate methyltransferase family signature 112 132 1.8E-23 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 PRINTS PR00996 Glutamate methyltransferase family signature 218 232 1.8E-23 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 hmeg3_RS23485 5e869a36db18adbb8283f2a3faa79b7a 285 Pfam PF03705 CheR methyltransferase, all-alpha domain 19 70 1.0E-10 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 197 4.1E-5 T 28-03-2018 hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 4.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 SUPERFAMILY SSF51735 10 248 1.67E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 13 248 1.7E-118 T 28-03-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 248 1.2E-54 T 28-03-2018 hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 Gene3D G3DSA:3.40.50.720 168 248 8.3E-24 T 28-03-2018 hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 Gene3D G3DSA:3.40.50.720 7 167 1.7E-42 T 28-03-2018 hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16255 fed5b23facd2e575352ebea2275fd392 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 SUPERFAMILY SSF56935 21 353 2.66E-84 T 28-03-2018 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 Pfam PF13609 Gram-negative porin 7 326 4.8E-54 T 28-03-2018 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 PRINTS PR00184 Neisseria sp. porin signature 55 80 3.8E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 PRINTS PR00184 Neisseria sp. porin signature 189 206 3.8E-6 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 8.6E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 188 200 8.6E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 53 64 8.6E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 300 317 8.6E-6 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS02725 72658245ab64344c000c7bc4572d52e0 353 Gene3D G3DSA:2.40.160.10 9 353 2.7E-77 T 28-03-2018 hmeg3_RS10435 3c72b3fd084832da34243c25077ad82a 161 PIRSF PIRSF003174 1 161 1.6E-60 T 28-03-2018 IPR010292 Uncharacterised protein family CreA hmeg3_RS10435 3c72b3fd084832da34243c25077ad82a 161 Pfam PF05981 CreA protein 28 153 2.8E-53 T 28-03-2018 IPR010292 Uncharacterised protein family CreA hmeg3_RS19320 2a3b36b379790d578701b6c2050c8df5 261 SMART SM00382 29 208 3.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19320 2a3b36b379790d578701b6c2050c8df5 261 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19320 2a3b36b379790d578701b6c2050c8df5 261 Pfam PF00005 ABC transporter 21 159 3.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19320 2a3b36b379790d578701b6c2050c8df5 261 SUPERFAMILY SSF52540 4 225 9.22E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19320 2a3b36b379790d578701b6c2050c8df5 261 Gene3D G3DSA:3.40.50.300 1 259 1.6E-54 T 28-03-2018 hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 Gene3D G3DSA:3.40.50.620 163 287 2.4E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 SUPERFAMILY SSF52402 1 156 4.6E-10 T 28-03-2018 hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 PRINTS PR01438 Universal stress protein signature 163 181 5.5E-5 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 PRINTS PR01438 Universal stress protein signature 265 287 5.5E-5 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 PRINTS PR01438 Universal stress protein signature 247 259 5.5E-5 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 SUPERFAMILY SSF52402 163 287 1.34E-12 T 28-03-2018 hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 Gene3D G3DSA:3.40.50.620 1 161 5.6E-11 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS11475 bd4e4f8ff4a749e6d0dbb36b0f140727 287 Pfam PF00582 Universal stress protein family 231 285 2.5E-5 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS09155 89bc7b58b817c03e914693489120479c 309 Gene3D G3DSA:3.40.190.10 40 176 7.7E-20 T 28-03-2018 hmeg3_RS09155 89bc7b58b817c03e914693489120479c 309 SUPERFAMILY SSF53850 16 280 7.81E-50 T 28-03-2018 hmeg3_RS09155 89bc7b58b817c03e914693489120479c 309 Gene3D G3DSA:3.40.190.10 177 309 9.2E-16 T 28-03-2018 hmeg3_RS09155 89bc7b58b817c03e914693489120479c 309 SMART SM00062 45 280 7.3E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09155 89bc7b58b817c03e914693489120479c 309 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 278 4.0E-43 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS09155 89bc7b58b817c03e914693489120479c 309 SMART SM00079 53 279 0.0093 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 hmeg3_RS20440 a94709ac50fdcb81e4fa9fbb5ce8cecb 147 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 136 8.3E-33 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 hmeg3_RS12015 a005e06e35bbe12b5ebff5035e15988d 348 Gene3D G3DSA:3.40.190.10 143 301 4.3E-31 T 28-03-2018 hmeg3_RS12015 a005e06e35bbe12b5ebff5035e15988d 348 Gene3D G3DSA:3.40.190.10 25 142 9.5E-8 T 28-03-2018 hmeg3_RS12015 a005e06e35bbe12b5ebff5035e15988d 348 SUPERFAMILY SSF53850 27 346 7.91E-64 T 28-03-2018 hmeg3_RS12015 a005e06e35bbe12b5ebff5035e15988d 348 Pfam PF13416 Bacterial extracellular solute-binding protein 45 303 1.5E-43 T 28-03-2018 hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 Pfam PF00005 ABC transporter 21 169 6.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 Pfam PF00005 ABC transporter 278 423 4.5E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 SMART SM00382 30 218 2.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 Gene3D G3DSA:3.40.50.300 243 505 8.0E-30 T 28-03-2018 hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 SUPERFAMILY SSF52540 264 498 1.17E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 Gene3D G3DSA:3.40.50.300 5 242 2.8E-48 T 28-03-2018 hmeg3_RS06725 74f32c3c02ba8c7518619346103abb94 530 SUPERFAMILY SSF52540 6 225 7.56E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05635 093e0464f4d575125633ac576216c951 328 SUPERFAMILY SSF53955 158 267 1.19E-19 T 28-03-2018 IPR023346 Lysozyme-like domain hmeg3_RS05635 093e0464f4d575125633ac576216c951 328 Pfam PF01464 Transglycosylase SLT domain 163 244 1.1E-15 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 hmeg3_RS05635 093e0464f4d575125633ac576216c951 328 Gene3D G3DSA:1.10.530.10 95 283 4.1E-18 T 28-03-2018 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 Gene3D G3DSA:3.40.50.2300 14 138 7.7E-29 T 28-03-2018 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 Gene3D G3DSA:1.10.10.10 139 218 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 SMART SM00421 153 210 6.8E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 5.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 Pfam PF00072 Response regulator receiver domain 17 128 9.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 SUPERFAMILY SSF52172 15 143 5.55E-30 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 SMART SM00448 15 128 5.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18725 8780bb8098b803e9e6f6af35c42218e9 219 SUPERFAMILY SSF46894 143 213 1.12E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS07245 53fb26b40b9611acc200d41d2527ab89 73 Gene3D G3DSA:3.30.429.10 2 70 2.1E-17 T 28-03-2018 hmeg3_RS07245 53fb26b40b9611acc200d41d2527ab89 73 SUPERFAMILY SSF55331 7 72 4.58E-20 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily hmeg3_RS07245 53fb26b40b9611acc200d41d2527ab89 73 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 14 73 1.0E-16 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 hmeg3_RS07245 53fb26b40b9611acc200d41d2527ab89 73 Pfam PF01361 Tautomerase enzyme 17 70 6.1E-15 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 SMART SM00564 155 186 0.17 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 SMART SM00564 77 108 12.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 SMART SM00564 330 361 0.49 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 SMART SM00564 115 146 140.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 SUPERFAMILY SSF50998 46 386 1.57E-67 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 Gene3D G3DSA:2.140.10.10 322 393 1.2E-6 T 28-03-2018 hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 Gene3D G3DSA:2.140.10.10 190 319 3.3E-8 T 28-03-2018 hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 24 390 3.4E-123 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 17 392 35.339 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 Gene3D G3DSA:2.140.10.10 54 189 8.0E-25 T 28-03-2018 hmeg3_RS08885 689e9652886658a8e300a119eec4258e 393 Pfam PF13360 PQQ-like domain 90 318 3.8E-48 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat hmeg3_RS05950 25f6fd719197cd142ef17922b6989806 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS05950 25f6fd719197cd142ef17922b6989806 307 Pfam PF03466 LysR substrate binding domain 88 293 1.7E-37 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS05950 25f6fd719197cd142ef17922b6989806 307 SUPERFAMILY SSF53850 90 296 4.89E-40 T 28-03-2018 hmeg3_RS05950 25f6fd719197cd142ef17922b6989806 307 Gene3D G3DSA:3.40.190.10 86 299 1.0E-24 T 28-03-2018 hmeg3_RS05950 25f6fd719197cd142ef17922b6989806 307 Gene3D G3DSA:1.10.10.10 3 84 9.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05950 25f6fd719197cd142ef17922b6989806 307 SUPERFAMILY SSF46785 3 111 6.53E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10710 e966b2a873b05e4f02aebc8610f717d8 390 Pfam PF01266 FAD dependent oxidoreductase 10 373 1.1E-30 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS10710 e966b2a873b05e4f02aebc8610f717d8 390 SUPERFAMILY SSF51905 361 384 1.29E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10710 e966b2a873b05e4f02aebc8610f717d8 390 SUPERFAMILY SSF51905 9 217 1.29E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10710 e966b2a873b05e4f02aebc8610f717d8 390 Gene3D G3DSA:3.40.50.720 9 381 1.1E-23 T 28-03-2018 hmeg3_RS10710 e966b2a873b05e4f02aebc8610f717d8 390 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 10 371 4.0E-128 T 28-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW hmeg3_RS12275 386e780f5dca37b3a41ffffe08e3ea2e 146 Gene3D G3DSA:1.20.1290.10 1 144 3.8E-40 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS12275 386e780f5dca37b3a41ffffe08e3ea2e 146 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 92 2.0E-19 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS12275 386e780f5dca37b3a41ffffe08e3ea2e 146 SUPERFAMILY SSF69118 5 142 3.21E-48 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS12275 386e780f5dca37b3a41ffffe08e3ea2e 146 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 32 77 6.1E-18 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 SUPERFAMILY SSF51905 5 172 1.19E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 SUPERFAMILY SSF51905 271 370 1.19E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 SUPERFAMILY SSF54373 177 276 1.73E-7 T 28-03-2018 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 Pfam PF01494 FAD binding domain 7 343 5.3E-24 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.4E-18 T 28-03-2018 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.4E-18 T 28-03-2018 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.4E-18 T 28-03-2018 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.4E-18 T 28-03-2018 hmeg3_RS19250 3c3e63f8b0278c4ad2c3d5104ee9bd76 383 Gene3D G3DSA:3.50.50.60 4 353 1.7E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS22540 1ac5ba57c8b7b21220ff07008e04176d 382 Pfam PF13458 Periplasmic binding protein 34 375 3.7E-58 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS22540 1ac5ba57c8b7b21220ff07008e04176d 382 Gene3D G3DSA:3.40.50.2300 32 162 1.4E-17 T 28-03-2018 hmeg3_RS22540 1ac5ba57c8b7b21220ff07008e04176d 382 Gene3D G3DSA:3.40.50.2300 163 332 1.9E-33 T 28-03-2018 hmeg3_RS22540 1ac5ba57c8b7b21220ff07008e04176d 382 SUPERFAMILY SSF53822 34 379 3.93E-79 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01065 5927e47a0b824efde248b2e9e802f4f7 328 Gene3D G3DSA:3.40.50.20 168 268 6.8E-4 T 28-03-2018 hmeg3_RS01065 5927e47a0b824efde248b2e9e802f4f7 328 Pfam PF02625 XdhC and CoxI family 15 83 6.2E-20 T 28-03-2018 IPR003777 XdhC- CoxI hmeg3_RS01065 5927e47a0b824efde248b2e9e802f4f7 328 Pfam PF13478 XdhC Rossmann domain 170 311 2.5E-39 T 28-03-2018 IPR027051 XdhC Rossmann domain hmeg3_RS05305 c7aa1dcf553e04176b76ac9579396b50 240 Gene3D G3DSA:2.60.120.10 132 238 2.2E-33 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS05305 c7aa1dcf553e04176b76ac9579396b50 240 Pfam PF02678 Pirin 10 119 5.0E-35 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 hmeg3_RS05305 c7aa1dcf553e04176b76ac9579396b50 240 PIRSF PIRSF006232 1 239 1.3E-54 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 hmeg3_RS05305 c7aa1dcf553e04176b76ac9579396b50 240 Gene3D G3DSA:2.60.120.10 12 131 7.6E-51 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS05305 c7aa1dcf553e04176b76ac9579396b50 240 SUPERFAMILY SSF51182 1 233 8.65E-78 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS07545 059d6c72e4024337736fa8dcc8163c6b 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 hmeg3_RS07545 059d6c72e4024337736fa8dcc8163c6b 265 SMART SM00062 35 255 7.1E-37 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS07545 059d6c72e4024337736fa8dcc8163c6b 265 Gene3D G3DSA:3.40.190.10 118 218 3.2E-18 T 28-03-2018 hmeg3_RS07545 059d6c72e4024337736fa8dcc8163c6b 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 4.8E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS07545 059d6c72e4024337736fa8dcc8163c6b 265 SUPERFAMILY SSF53850 27 257 3.42E-53 T 28-03-2018 hmeg3_RS07545 059d6c72e4024337736fa8dcc8163c6b 265 Gene3D G3DSA:3.40.190.10 30 117 1.5E-23 T 28-03-2018 hmeg3_RS05225 71c65ccd3f1b04721c05ea6563f71281 1208 Pfam PF02538 Hydantoinase B/oxoprolinase 700 1207 1.7E-204 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 hmeg3_RS05225 71c65ccd3f1b04721c05ea6563f71281 1208 Pfam PF01968 Hydantoinase/oxoprolinase 213 500 2.2E-114 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 hmeg3_RS05225 71c65ccd3f1b04721c05ea6563f71281 1208 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 15 193 3.9E-60 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 hmeg3_RS05225 71c65ccd3f1b04721c05ea6563f71281 1208 Gene3D G3DSA:3.30.420.40 17 313 0.011 T 28-03-2018 hmeg3_RS04245 47939eeca2ef35eb7210eb0d9b6ba30e 262 Gene3D G3DSA:2.40.128.100 21 262 8.1E-24 T 28-03-2018 hmeg3_RS04245 47939eeca2ef35eb7210eb0d9b6ba30e 262 SUPERFAMILY SSF69917 38 262 1.78E-27 T 28-03-2018 IPR020080 Outer membrane adhesin/peptidase omptin GO:0004190 hmeg3_RS21300 cec127f1878e30b0fab618921bb739ff 551 Gene3D G3DSA:3.90.550.10 4 219 2.1E-13 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21300 cec127f1878e30b0fab618921bb739ff 551 Pfam PF00248 Aldo/keto reductase family 251 534 1.0E-25 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS21300 cec127f1878e30b0fab618921bb739ff 551 Pfam PF02348 Cytidylyltransferase 6 170 1.6E-15 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 hmeg3_RS21300 cec127f1878e30b0fab618921bb739ff 551 SUPERFAMILY SSF51430 244 537 2.62E-36 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS21300 cec127f1878e30b0fab618921bb739ff 551 SUPERFAMILY SSF53448 5 202 3.38E-18 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21300 cec127f1878e30b0fab618921bb739ff 551 Gene3D G3DSA:3.20.20.100 239 538 7.4E-35 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS07905 68fd4a84b7ddeaec14913a06b81039a3 123 Gene3D G3DSA:1.10.10.10 20 60 0.013 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19780 fe6742fb7833fa9111a8c551d4ed05a6 319 SUPERFAMILY SSF52540 15 157 4.94E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19780 fe6742fb7833fa9111a8c551d4ed05a6 319 Gene3D G3DSA:1.10.287.890 208 291 9.1E-26 T 28-03-2018 hmeg3_RS19780 fe6742fb7833fa9111a8c551d4ed05a6 319 Gene3D G3DSA:3.40.50.300 10 199 2.4E-65 T 28-03-2018 hmeg3_RS19780 fe6742fb7833fa9111a8c551d4ed05a6 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 14 293 7.2E-97 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 hmeg3_RS19780 fe6742fb7833fa9111a8c551d4ed05a6 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 13 318 30.299 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 hmeg3_RS19780 fe6742fb7833fa9111a8c551d4ed05a6 319 Pfam PF01715 IPP transferase 47 293 1.4E-88 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 hmeg3_RS02710 0457973f8900ebcc852607a9d2d8c290 372 SUPERFAMILY SSF53850 48 350 1.13E-52 T 28-03-2018 hmeg3_RS02710 0457973f8900ebcc852607a9d2d8c290 372 Gene3D G3DSA:3.40.190.10 7 220 1.0E-22 T 28-03-2018 hmeg3_RS02710 0457973f8900ebcc852607a9d2d8c290 372 Gene3D G3DSA:3.40.190.10 221 341 4.4E-14 T 28-03-2018 hmeg3_RS02710 0457973f8900ebcc852607a9d2d8c290 372 Pfam PF13343 Bacterial extracellular solute-binding protein 104 330 1.9E-13 T 28-03-2018 hmeg3_RS21385 5b3f9a13762a89bdef277555cd903679 176 SUPERFAMILY SSF53271 16 149 2.49E-32 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS21385 5b3f9a13762a89bdef277555cd903679 176 Pfam PF00156 Phosphoribosyl transferase domain 18 146 6.6E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 hmeg3_RS21385 5b3f9a13762a89bdef277555cd903679 176 Gene3D G3DSA:3.40.50.2020 6 168 1.9E-25 T 28-03-2018 hmeg3_RS17535 89b4dee811769296a7e578d1c4a28106 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 288 2.1E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17535 89b4dee811769296a7e578d1c4a28106 294 Gene3D G3DSA:1.10.3720.10 24 286 2.4E-39 T 28-03-2018 hmeg3_RS17535 89b4dee811769296a7e578d1c4a28106 294 SUPERFAMILY SSF161098 22 289 6.26E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 Pfam PF00106 short chain dehydrogenase 7 184 3.3E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 Gene3D G3DSA:3.40.50.720 1 233 7.9E-46 T 28-03-2018 hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 3.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.3E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS11805 2e4bc1c1a2e306a05428a35dd2306f7b 235 SUPERFAMILY SSF51735 4 207 1.68E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS13975 2909a17b41ea7a57f372990847295c0d 219 Pfam PF11304 Protein of unknown function (DUF3106) 66 165 2.2E-31 T 28-03-2018 IPR021455 Protein of unknown function DUF3106 hmeg3_RS06895 994986d1127eb3e8493ef25fd0587a5e 424 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 30 207 1.9E-55 T 28-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 hmeg3_RS06895 994986d1127eb3e8493ef25fd0587a5e 424 Gene3D G3DSA:3.30.2010.10 206 288 3.4E-22 T 28-03-2018 hmeg3_RS06895 994986d1127eb3e8493ef25fd0587a5e 424 Pfam PF01435 Peptidase family M48 211 418 1.2E-37 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 SUPERFAMILY SSF51735 4 251 7.25E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.8E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.8E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.8E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.8E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.8E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.8E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 2.8E-64 T 28-03-2018 hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 Gene3D G3DSA:3.40.50.720 43 252 3.7E-61 T 28-03-2018 hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 Gene3D G3DSA:3.40.50.720 1 42 1.9E-10 T 28-03-2018 hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS10685 0d075f109099b0a71efda716b072fede 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15845 1120b424f14019761e3481899bb6d5d8 178 Pfam PF12833 Helix-turn-helix domain 96 171 1.0E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS15845 1120b424f14019761e3481899bb6d5d8 178 SUPERFAMILY SSF46689 126 168 7.17E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS15845 1120b424f14019761e3481899bb6d5d8 178 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 127 169 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 hmeg3_RS15845 1120b424f14019761e3481899bb6d5d8 178 Gene3D G3DSA:1.10.10.60 66 129 9.9E-9 T 28-03-2018 hmeg3_RS15845 1120b424f14019761e3481899bb6d5d8 178 SMART SM00342 90 173 7.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS15845 1120b424f14019761e3481899bb6d5d8 178 Gene3D G3DSA:1.10.10.60 130 177 9.9E-8 T 28-03-2018 hmeg3_RS05705 7b379bf73689d4f3fd63867de4e9d0d1 553 SUPERFAMILY SSF56645 51 295 4.79E-35 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 hmeg3_RS05705 7b379bf73689d4f3fd63867de4e9d0d1 553 Gene3D G3DSA:1.20.140.10 283 445 9.3E-36 T 28-03-2018 hmeg3_RS05705 7b379bf73689d4f3fd63867de4e9d0d1 553 SUPERFAMILY SSF47203 293 445 1.77E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS05705 7b379bf73689d4f3fd63867de4e9d0d1 553 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 278 1.1E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 hmeg3_RS05705 7b379bf73689d4f3fd63867de4e9d0d1 553 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 442 3.1E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 hmeg3_RS05705 7b379bf73689d4f3fd63867de4e9d0d1 553 Gene3D G3DSA:2.40.110.10 180 282 6.8E-21 T 28-03-2018 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 Gene3D G3DSA:1.10.760.10 228 426 2.6E-32 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 Pfam PF00034 Cytochrome c 245 416 1.3E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 SUPERFAMILY SSF46626 318 417 7.97E-32 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 SUPERFAMILY SSF46626 220 287 7.97E-32 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 Gene3D G3DSA:1.10.760.10 45 227 3.4E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 SUPERFAMILY SSF46626 41 218 1.05E-30 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS17425 45b3007c930df94f7d2e22391d0a08cb 426 Pfam PF03150 Di-haem cytochrome c peroxidase 57 237 2.2E-34 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 hmeg3_RS16310 c62894dd772608b5240f5af01989853d 332 SUPERFAMILY SSF53697 110 277 3.03E-28 T 28-03-2018 hmeg3_RS16310 c62894dd772608b5240f5af01989853d 332 SUPERFAMILY SSF46689 19 89 9.68E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS16310 c62894dd772608b5240f5af01989853d 332 Gene3D G3DSA:3.40.50.10490 134 276 2.1E-22 T 28-03-2018 hmeg3_RS16310 c62894dd772608b5240f5af01989853d 332 Pfam PF01380 SIS domain 139 264 6.8E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS16310 c62894dd772608b5240f5af01989853d 332 Gene3D G3DSA:1.10.10.10 14 133 2.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16310 c62894dd772608b5240f5af01989853d 332 Pfam PF01418 Helix-turn-helix domain, rpiR family 19 88 2.2E-13 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 hmeg3_RS00885 e32f765204340dc4edc2098f01069738 119 SUPERFAMILY SSF52091 1 110 1.82E-21 T 28-03-2018 IPR002645 STAS domain hmeg3_RS00885 e32f765204340dc4edc2098f01069738 119 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 104 7.7E-17 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 hmeg3_RS00885 e32f765204340dc4edc2098f01069738 119 Pfam PF01740 STAS domain 3 105 1.6E-14 T 28-03-2018 IPR002645 STAS domain hmeg3_RS00885 e32f765204340dc4edc2098f01069738 119 Gene3D G3DSA:3.30.750.24 1 113 1.3E-22 T 28-03-2018 IPR002645 STAS domain hmeg3_RS22860 34c79b4a7ae52c742029a5d254941527 218 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site hmeg3_RS22860 34c79b4a7ae52c742029a5d254941527 218 Pfam PF00297 Ribosomal protein L3 57 185 6.1E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22860 34c79b4a7ae52c742029a5d254941527 218 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 206 1.3E-84 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22860 34c79b4a7ae52c742029a5d254941527 218 SUPERFAMILY SSF50447 2 215 3.97E-77 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain hmeg3_RS22860 34c79b4a7ae52c742029a5d254941527 218 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 37.672 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS22860 34c79b4a7ae52c742029a5d254941527 218 Gene3D G3DSA:4.10.960.10 47 168 3.4E-28 T 28-03-2018 hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 Gene3D G3DSA:2.40.50.140 62 156 1.4E-7 T 28-03-2018 hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 SMART SM00487 278 486 1.0E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 Pfam PF00270 DEAD/DEAH box helicase 304 461 1.5E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 Gene3D G3DSA:3.40.50.300 266 483 1.9E-37 T 28-03-2018 hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 SUPERFAMILY SSF50249 35 188 1.03E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 Gene3D G3DSA:3.40.50.300 484 656 1.3E-29 T 28-03-2018 hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 SUPERFAMILY SSF52540 193 480 8.71E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 SMART SM00490 532 615 4.1E-22 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 Pfam PF00271 Helicase conserved C-terminal domain 505 614 1.9E-17 T 28-03-2018 IPR001650 Helicase, C-terminal hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 Pfam PF17191 RecG wedge domain 34 186 1.1E-10 T 28-03-2018 IPR033454 RecG, wedge domain hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 SUPERFAMILY SSF52540 479 681 5.89E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05025 bd5498d8c5216e9bbfe59232f5b8cba2 719 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 48 690 6.7E-213 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 hmeg3_RS05185 ba164c1f21c829807ac8ed6c989cad76 72 SUPERFAMILY SSF55174 3 69 1.11E-17 T 28-03-2018 hmeg3_RS05185 ba164c1f21c829807ac8ed6c989cad76 72 Gene3D G3DSA:3.10.290.10 1 71 8.6E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS05185 ba164c1f21c829807ac8ed6c989cad76 72 Pfam PF13275 S4 domain 6 69 1.5E-22 T 28-03-2018 hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 SMART SM00267 183 363 2.0E-59 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 Pfam PF04340 Protein of unknown function, DUF484 11 182 2.3E-13 T 28-03-2018 IPR007435 Protein of unknown function DUF484 hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 191 363 5.8E-55 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 Gene3D G3DSA:3.30.70.270 190 364 1.0E-56 T 28-03-2018 hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 SUPERFAMILY SSF55073 199 362 2.04E-46 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 Gene3D G3DSA:3.30.450.40 3 189 1.9E-12 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 SUPERFAMILY SSF55781 52 191 2.07E-9 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS03405 89e375f6d6c56d419329e7ebe0808d24 364 Pfam PF00990 Diguanylate cyclase, GGDEF domain 196 359 3.0E-49 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09415 3b2832f00aeb0d0293813b87c33ccbb8 295 Gene3D G3DSA:1.10.3720.10 44 294 1.9E-36 T 28-03-2018 hmeg3_RS09415 3b2832f00aeb0d0293813b87c33ccbb8 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 288 4.6E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09415 3b2832f00aeb0d0293813b87c33ccbb8 295 SUPERFAMILY SSF161098 97 283 2.09E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19945 3eb6c6f44a839595299f24e265d33ee8 107 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 10 93 1.2E-35 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 hmeg3_RS10550 17e94717a02b3a40944c109f36dd4818 304 Gene3D G3DSA:1.10.3470.10 1 293 1.3E-41 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS10550 17e94717a02b3a40944c109f36dd4818 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 268 1.7E-31 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 135 158 - T 28-03-2018 IPR025505 FHIPEP conserved site hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PIRSF PIRSF005419 1 691 1.3E-209 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 TIGRFAM TIGR01399 hrcV: type III secretion protein, HrcV family 12 690 4.8E-258 T 28-03-2018 IPR006302 Type III secretion protein HrcV GO:0015031|GO:0016021 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 230 244 8.0E-58 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 149 167 8.0E-58 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 130 146 8.0E-58 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 179 196 8.0E-58 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 68 87 8.0E-58 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 31 44 8.0E-58 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS15830 45ff274c146ce5744c39094d943695e1 691 Pfam PF00771 FHIPEP family 24 683 2.7E-212 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 Gene3D G3DSA:3.50.50.60 1 151 1.9E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.7E-37 T 28-03-2018 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.7E-37 T 28-03-2018 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.7E-37 T 28-03-2018 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.7E-37 T 28-03-2018 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.7E-37 T 28-03-2018 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 5.5E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 2.6E-119 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 SUPERFAMILY SSF51905 1 314 8.6E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 Gene3D G3DSA:3.40.50.720 152 317 3.6E-23 T 28-03-2018 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS16835 2e2dbd116133599b8755706486dcaade 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 4.3E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02255 631f81dfe76dd2eafdd011b3e8a8c461 337 Pfam PF01548 Transposase 4 148 5.0E-17 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 hmeg3_RS02255 631f81dfe76dd2eafdd011b3e8a8c461 337 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 297 5.1E-16 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 hmeg3_RS20600 631f81dfe76dd2eafdd011b3e8a8c461 337 Pfam PF01548 Transposase 4 148 5.0E-17 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 hmeg3_RS20600 631f81dfe76dd2eafdd011b3e8a8c461 337 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 297 5.1E-16 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 hmeg3_RS23800 631f81dfe76dd2eafdd011b3e8a8c461 337 Pfam PF01548 Transposase 4 148 5.0E-17 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 hmeg3_RS23800 631f81dfe76dd2eafdd011b3e8a8c461 337 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 297 5.1E-16 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 hmeg3_RS19060 b11a6c80aa9a49f7db3d57ed75f34afc 410 Pfam PF02321 Outer membrane efflux protein 31 205 3.5E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS19060 b11a6c80aa9a49f7db3d57ed75f34afc 410 Pfam PF02321 Outer membrane efflux protein 236 404 3.7E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS19060 b11a6c80aa9a49f7db3d57ed75f34afc 410 Gene3D G3DSA:1.20.1600.10 16 406 1.0E-69 T 28-03-2018 hmeg3_RS19060 b11a6c80aa9a49f7db3d57ed75f34afc 410 SUPERFAMILY SSF56954 3 404 1.44E-81 T 28-03-2018 hmeg3_RS23695 8c48d96acbe9bac66c8938f760524132 331 Gene3D G3DSA:3.40.190.10 140 330 1.2E-22 T 28-03-2018 hmeg3_RS23695 8c48d96acbe9bac66c8938f760524132 331 Pfam PF09084 NMT1/THI5 like 48 257 6.6E-28 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS23695 8c48d96acbe9bac66c8938f760524132 331 SUPERFAMILY SSF53850 39 265 1.58E-32 T 28-03-2018 hmeg3_RS23695 8c48d96acbe9bac66c8938f760524132 331 Gene3D G3DSA:3.40.190.10 34 139 2.8E-11 T 28-03-2018 hmeg3_RS23900 d45ceb0bae2e3e4426bfa64b9d3ee2d5 268 SUPERFAMILY SSF53187 3 263 1.46E-83 T 28-03-2018 hmeg3_RS23900 d45ceb0bae2e3e4426bfa64b9d3ee2d5 268 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 6 263 2.7E-113 T 28-03-2018 IPR010247 N-formylglutamate deformylase hmeg3_RS23900 d45ceb0bae2e3e4426bfa64b9d3ee2d5 268 Pfam PF05013 N-formylglutamate amidohydrolase 14 234 8.0E-73 T 28-03-2018 IPR007709 N-formylglutamate amidohydrolase hmeg3_RS23900 d45ceb0bae2e3e4426bfa64b9d3ee2d5 268 Gene3D G3DSA:3.40.630.40 1 267 5.3E-81 T 28-03-2018 hmeg3_RS11205 3cfd956d2ded8e47418db83393ec11ec 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 265 1.8E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11205 3cfd956d2ded8e47418db83393ec11ec 288 Gene3D G3DSA:1.10.3720.10 31 275 7.5E-26 T 28-03-2018 hmeg3_RS11205 3cfd956d2ded8e47418db83393ec11ec 288 SUPERFAMILY SSF161098 87 273 4.32E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12370 9a25702d35ec761dc8b69e7519b56e60 328 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 12 310 3.4E-56 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 hmeg3_RS12370 9a25702d35ec761dc8b69e7519b56e60 328 Pfam PF03186 CobD/Cbib protein 14 293 1.4E-89 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 hmeg3_RS12370 9a25702d35ec761dc8b69e7519b56e60 328 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 314 97.771 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 hmeg3_RS11125 56f7b3c8aa7975222c19b990562dfef7 125 Pfam PF01597 Glycine cleavage H-protein 7 124 3.2E-36 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate hmeg3_RS11125 56f7b3c8aa7975222c19b990562dfef7 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 hmeg3_RS11125 56f7b3c8aa7975222c19b990562dfef7 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 34.402 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 hmeg3_RS11125 56f7b3c8aa7975222c19b990562dfef7 125 SUPERFAMILY SSF51230 3 124 2.36E-33 T 28-03-2018 IPR011053 Single hybrid motif hmeg3_RS11125 56f7b3c8aa7975222c19b990562dfef7 125 Gene3D G3DSA:2.40.50.100 5 125 4.8E-35 T 28-03-2018 hmeg3_RS11125 56f7b3c8aa7975222c19b990562dfef7 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 124 2.8E-36 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 SUPERFAMILY SSF54292 7 81 4.72E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 SUPERFAMILY SSF47741 94 162 3.66E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 Gene3D G3DSA:1.10.150.120 79 171 1.9E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 Gene3D G3DSA:3.10.20.30 2 78 4.7E-24 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 56 2.8E-5 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS19245 16b32ccb223e80fa57930687856d16b2 172 Pfam PF01799 [2Fe-2S] binding domain 77 155 2.7E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 SUPERFAMILY SSF55103 201 469 1.8E-72 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 8.8E-62 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 Gene3D G3DSA:3.30.465.10 105 248 4.8E-38 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 Gene3D G3DSA:3.30.43.10 2 104 4.7E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 Pfam PF01565 FAD binding domain 52 191 4.8E-38 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 SUPERFAMILY SSF56176 16 227 1.54E-71 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS04840 82a82b33c87767549bc07abd98c60242 495 Gene3D G3DSA:1.10.45.10 428 466 2.8E-9 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 4.7E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 427 2.1E-208 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS02360 6e562b7545222963664e11975e68ec2c 427 Pfam PF02040 Arsenical pump membrane protein 4 423 4.3E-156 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS18325 7f5d665044484a0f31d79e73a831390c 126 SUPERFAMILY SSF141488 40 121 3.14E-18 T 28-03-2018 IPR018660 C-type lysozyme inhibitor hmeg3_RS18325 7f5d665044484a0f31d79e73a831390c 126 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 45 110 3.4E-15 T 28-03-2018 IPR018660 C-type lysozyme inhibitor hmeg3_RS19280 33ab3912c4b0f749b15d218de30f6ea5 156 SUPERFAMILY SSF46785 17 155 3.33E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19280 33ab3912c4b0f749b15d218de30f6ea5 156 SMART SM00347 44 144 4.7E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS19280 33ab3912c4b0f749b15d218de30f6ea5 156 Gene3D G3DSA:1.10.10.10 2 156 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19280 33ab3912c4b0f749b15d218de30f6ea5 156 Pfam PF13463 Winged helix DNA-binding domain 51 117 8.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS14695 510871c2992d95d7d326d1fafc232480 463 Gene3D G3DSA:3.40.50.10540 204 460 6.3E-64 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS14695 510871c2992d95d7d326d1fafc232480 463 Gene3D G3DSA:3.30.1540.10 102 189 7.2E-7 T 28-03-2018 hmeg3_RS14695 510871c2992d95d7d326d1fafc232480 463 SUPERFAMILY SSF89796 207 409 6.02E-55 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS14695 510871c2992d95d7d326d1fafc232480 463 Pfam PF02515 CoA-transferase family III 210 400 1.3E-46 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 hmeg3_RS14695 510871c2992d95d7d326d1fafc232480 463 SUPERFAMILY SSF89796 36 194 1.31E-20 T 28-03-2018 IPR023606 CoA-transferase family III domain hmeg3_RS13495 b7f3edc4ab2088104c7857430f0bc092 245 Pfam PF00117 Glutamine amidotransferase class-I 44 176 4.4E-8 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS13495 b7f3edc4ab2088104c7857430f0bc092 245 SUPERFAMILY SSF52317 4 187 3.36E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS13495 b7f3edc4ab2088104c7857430f0bc092 245 Gene3D G3DSA:3.40.50.880 2 229 3.2E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10830 240ecccfc6e9be7f520d5ed255d09f9c 127 SUPERFAMILY SSF54427 14 126 1.14E-9 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS10830 240ecccfc6e9be7f520d5ed255d09f9c 127 Gene3D G3DSA:3.10.450.50 12 126 1.2E-21 T 28-03-2018 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 9.7E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 136 9.7E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 167 191 9.7E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 SUPERFAMILY SSF51905 10 209 2.33E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 14 324 2.4E-24 T 28-03-2018 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 Gene3D G3DSA:3.50.50.60 154 285 5.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 Gene3D G3DSA:3.50.50.60 11 153 1.6E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.1E-9 T 28-03-2018 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 2.1E-9 T 28-03-2018 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 295 2.1E-9 T 28-03-2018 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 2.1E-9 T 28-03-2018 hmeg3_RS02335 63194d9c4a5ac56c6bd2e639bce1174a 361 SUPERFAMILY SSF51905 168 354 3.41E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS22755 22a2a0cc781befb686991144e38daee7 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.9E-26 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 hmeg3_RS22755 22a2a0cc781befb686991144e38daee7 72 SUPERFAMILY SSF50249 1 70 1.14E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS22755 22a2a0cc781befb686991144e38daee7 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 3.2E-36 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 hmeg3_RS22755 22a2a0cc781befb686991144e38daee7 72 Gene3D G3DSA:2.40.50.140 1 72 3.4E-34 T 28-03-2018 hmeg3_RS22755 22a2a0cc781befb686991144e38daee7 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.81 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 hmeg3_RS22755 22a2a0cc781befb686991144e38daee7 72 SMART SM00316 2 72 0.0055 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS06385 ec67b5409e28ff8f5671a38ed0e51153 255 SUPERFAMILY SSF53474 30 250 3.77E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06385 ec67b5409e28ff8f5671a38ed0e51153 255 Pfam PF12697 Alpha/beta hydrolase family 35 248 2.0E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS06385 ec67b5409e28ff8f5671a38ed0e51153 255 Gene3D G3DSA:3.40.50.1820 21 254 5.8E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 3.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 3.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 3.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 Gene3D G3DSA:3.40.50.2300 2 118 1.0E-26 T 28-03-2018 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 7.7E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 Gene3D G3DSA:1.10.10.10 119 201 3.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 SUPERFAMILY SSF52172 5 162 1.1E-29 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 SMART SM00421 138 195 4.4E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 SMART SM00448 3 114 4.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05370 82d38f24d0859d80d1b626ce6dd52752 206 Pfam PF00072 Response regulator receiver domain 5 114 1.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS21320 45367dfab6ae7ae7c95a9cc4e16a0ca1 419 PIRSF PIRSF015244 1 419 2.4E-157 T 28-03-2018 IPR012353 Uncharacterised conserved protein UCP01524, polysaccharide biosynthesis aminopeptidase-like hmeg3_RS21320 45367dfab6ae7ae7c95a9cc4e16a0ca1 419 Pfam PF09940 Domain of unknown function (DUF2172) 53 144 3.2E-38 T 28-03-2018 IPR032610 Domain of unknown function DUF2172 hmeg3_RS21320 45367dfab6ae7ae7c95a9cc4e16a0ca1 419 Pfam PF16221 winged helix-turn-helix 346 417 2.6E-25 T 28-03-2018 IPR032622 UCP01524, winged helix-turn-helix domain hmeg3_RS21320 45367dfab6ae7ae7c95a9cc4e16a0ca1 419 Pfam PF16254 Domain of unknown function (DUF4910) 2 342 5.7E-100 T 28-03-2018 IPR032589 Domain of unknown function DUF4910 hmeg3_RS21320 45367dfab6ae7ae7c95a9cc4e16a0ca1 419 Gene3D G3DSA:3.40.630.10 138 342 6.0E-12 T 28-03-2018 hmeg3_RS21320 45367dfab6ae7ae7c95a9cc4e16a0ca1 419 SUPERFAMILY SSF53187 77 341 8.32E-37 T 28-03-2018 hmeg3_RS15120 0adb5bf0f020076c443bfa2ed470245c 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 206 1.4E-22 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS15120 0adb5bf0f020076c443bfa2ed470245c 324 SUPERFAMILY SSF51735 1 321 5.97E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS15120 0adb5bf0f020076c443bfa2ed470245c 324 Gene3D G3DSA:3.90.25.10 187 290 4.1E-45 T 28-03-2018 hmeg3_RS15120 0adb5bf0f020076c443bfa2ed470245c 324 Gene3D G3DSA:3.40.50.720 1 186 6.4E-30 T 28-03-2018 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 PIRSF PIRSF038994 5 379 4.4E-99 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 SUPERFAMILY SSF51338 8 55 5.5E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 SUPERFAMILY SSF51338 347 375 5.5E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 SUPERFAMILY SSF51556 56 346 4.88E-84 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 Gene3D G3DSA:3.20.20.140 70 347 4.4E-88 T 28-03-2018 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 Gene3D G3DSA:2.30.40.10 6 69 7.5E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 Pfam PF01979 Amidohydrolase family 52 374 2.7E-14 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS11015 86a0a976642719242906bd7fd8aeeb6f 381 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 49 373 5.3E-78 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 hmeg3_RS02845 c5c1afd8a1aa93a1a9d01af3b6eaf96a 221 Gene3D G3DSA:3.30.450.40 39 218 3.6E-10 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS02845 c5c1afd8a1aa93a1a9d01af3b6eaf96a 221 Pfam PF04340 Protein of unknown function, DUF484 3 211 1.9E-35 T 28-03-2018 IPR007435 Protein of unknown function DUF484 hmeg3_RS23720 97ccb2d9bb6834a1960f4db25cca6a78 240 Pfam PF13317 Protein of unknown function (DUF4088) 16 240 1.5E-98 T 28-03-2018 IPR025146 Protein of unknown function DUF4088 hmeg3_RS19585 85c1917c38af1fb3ecb532b12bfbc0d6 325 Gene3D G3DSA:3.20.20.140 1 325 4.8E-60 T 28-03-2018 hmeg3_RS19585 85c1917c38af1fb3ecb532b12bfbc0d6 325 Pfam PF04909 Amidohydrolase 2 325 2.9E-41 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS19585 85c1917c38af1fb3ecb532b12bfbc0d6 325 SUPERFAMILY SSF51556 1 325 3.89E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS08980 1b5733f4821c20b7471a8f0de39af26c 264 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 259 98.798 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 hmeg3_RS08980 1b5733f4821c20b7471a8f0de39af26c 264 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 17 219 9.1E-8 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 hmeg3_RS08980 1b5733f4821c20b7471a8f0de39af26c 264 Gene3D G3DSA:3.60.21.10 16 237 1.1E-19 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS08980 1b5733f4821c20b7471a8f0de39af26c 264 SUPERFAMILY SSF56300 17 234 2.35E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS08980 1b5733f4821c20b7471a8f0de39af26c 264 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 16 234 3.7E-80 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 Pfam PF03466 LysR substrate binding domain 92 297 2.4E-33 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 2.4E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 SUPERFAMILY SSF53850 93 297 2.17E-35 T 28-03-2018 hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 Gene3D G3DSA:3.40.190.10 94 181 1.9E-12 T 28-03-2018 hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 Gene3D G3DSA:3.40.190.10 182 272 8.9E-24 T 28-03-2018 hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 Gene3D G3DSA:1.10.10.10 5 93 8.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12085 2e53d71247afced6a1b2531478f3ebe6 298 SUPERFAMILY SSF46785 8 116 8.35E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS12585 e89abb9c4eab33ca4a2675d96b8207d7 159 Pfam PF03061 Thioesterase superfamily 23 96 1.7E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS12585 e89abb9c4eab33ca4a2675d96b8207d7 159 Gene3D G3DSA:3.10.129.10 1 157 1.2E-49 T 28-03-2018 hmeg3_RS12585 e89abb9c4eab33ca4a2675d96b8207d7 159 SUPERFAMILY SSF54637 2 155 5.85E-47 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS21395 afed5ffab85d8e54eca16a73d88711da 232 Pfam PF02622 Uncharacterized ACR, COG1678 53 219 2.5E-47 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 hmeg3_RS21395 afed5ffab85d8e54eca16a73d88711da 232 Gene3D G3DSA:3.30.70.1300 83 165 4.7E-28 T 28-03-2018 hmeg3_RS21395 afed5ffab85d8e54eca16a73d88711da 232 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 42 232 36.726 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 hmeg3_RS21395 afed5ffab85d8e54eca16a73d88711da 232 SUPERFAMILY SSF143456 44 231 3.79E-63 T 28-03-2018 hmeg3_RS21395 afed5ffab85d8e54eca16a73d88711da 232 Gene3D G3DSA:3.40.1740.10 166 223 8.1E-11 T 28-03-2018 hmeg3_RS06180 e3655263c40946d8829181c2d596f213 335 SUPERFAMILY SSF161098 41 319 2.62E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS06180 e3655263c40946d8829181c2d596f213 335 Gene3D G3DSA:1.10.3720.10 21 322 3.9E-36 T 28-03-2018 hmeg3_RS06180 e3655263c40946d8829181c2d596f213 335 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 35 327 4.5E-95 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 hmeg3_RS06180 e3655263c40946d8829181c2d596f213 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 323 2.2E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS05555 2db0fad5a4a7847da47aaabe8e9210c7 77 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 9 33 - T 28-03-2018 IPR001455 TusA-like domain hmeg3_RS05555 2db0fad5a4a7847da47aaabe8e9210c7 77 Gene3D G3DSA:3.30.110.40 2 77 4.4E-27 T 28-03-2018 IPR001455 TusA-like domain hmeg3_RS05555 2db0fad5a4a7847da47aaabe8e9210c7 77 Pfam PF01206 Sulfurtransferase TusA 8 75 1.6E-23 T 28-03-2018 IPR001455 TusA-like domain hmeg3_RS05555 2db0fad5a4a7847da47aaabe8e9210c7 77 SUPERFAMILY SSF64307 2 76 3.01E-24 T 28-03-2018 IPR001455 TusA-like domain hmeg3_RS14860 96bb77edc3946f1cda81c4942caee516 176 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 60 167 4.6E-11 T 28-03-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 hmeg3_RS14860 96bb77edc3946f1cda81c4942caee516 176 Gene3D G3DSA:2.60.40.420 57 169 5.2E-23 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS14860 96bb77edc3946f1cda81c4942caee516 176 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 67 166 4.0E-4 T 28-03-2018 hmeg3_RS14860 96bb77edc3946f1cda81c4942caee516 176 SUPERFAMILY SSF49503 57 167 1.44E-31 T 28-03-2018 IPR008972 Cupredoxin hmeg3_RS09060 097e98336141810cd6d89e2450a7ad92 833 Pfam PF02687 FtsX-like permease family 294 378 1.2E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 hmeg3_RS09060 097e98336141810cd6d89e2450a7ad92 833 Pfam PF02687 FtsX-like permease family 738 824 4.6E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 hmeg3_RS02865 debebad1d1180b96b14f344169645a0e 293 PIRSF PIRSF026649 1 288 2.5E-78 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 hmeg3_RS02865 debebad1d1180b96b14f344169645a0e 293 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 280 2.3E-64 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 hmeg3_RS20810 2e7c03811d91e62f4333ac809eea8f06 208 Pfam PF03458 UPF0126 domain 7 78 7.2E-19 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 hmeg3_RS20810 2e7c03811d91e62f4333ac809eea8f06 208 Pfam PF03458 UPF0126 domain 91 164 7.5E-22 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 hmeg3_RS17655 1069551e66fab88404db5f0256248c48 424 Gene3D G3DSA:3.40.50.2300 234 379 2.8E-20 T 28-03-2018 hmeg3_RS17655 1069551e66fab88404db5f0256248c48 424 SUPERFAMILY SSF53822 46 395 3.7E-75 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS17655 1069551e66fab88404db5f0256248c48 424 Gene3D G3DSA:3.40.50.2300 43 233 4.1E-28 T 28-03-2018 hmeg3_RS17655 1069551e66fab88404db5f0256248c48 424 Pfam PF13458 Periplasmic binding protein 46 384 2.4E-68 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS19900 bc95bfd19301643e0b3e2b4824c56d97 352 SUPERFAMILY SSF53659 16 347 7.38E-103 T 28-03-2018 hmeg3_RS19900 bc95bfd19301643e0b3e2b4824c56d97 352 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 14 346 36.371 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 hmeg3_RS19900 bc95bfd19301643e0b3e2b4824c56d97 352 Gene3D G3DSA:3.40.718.10 8 352 8.0E-133 T 28-03-2018 hmeg3_RS19900 bc95bfd19301643e0b3e2b4824c56d97 352 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 45 342 7.9E-109 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 hmeg3_RS19900 bc95bfd19301643e0b3e2b4824c56d97 352 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 18 346 4.6E-126 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 hmeg3_RS11000 f62e0c0649eec69c497bfc174b763a9d 260 Gene3D G3DSA:3.40.190.10 143 257 1.6E-9 T 28-03-2018 hmeg3_RS11000 f62e0c0649eec69c497bfc174b763a9d 260 Pfam PF13531 Bacterial extracellular solute-binding protein 26 251 7.0E-33 T 28-03-2018 hmeg3_RS11000 f62e0c0649eec69c497bfc174b763a9d 260 Gene3D G3DSA:3.40.190.10 25 142 5.9E-17 T 28-03-2018 hmeg3_RS11000 f62e0c0649eec69c497bfc174b763a9d 260 SUPERFAMILY SSF53850 25 251 5.44E-42 T 28-03-2018 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 SUPERFAMILY SSF54292 2 89 1.06E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 Gene3D G3DSA:3.10.20.30 1 96 3.4E-22 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 SUPERFAMILY SSF63380 102 199 6.81E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 Pfam PF00175 Oxidoreductase NAD-binding domain 209 314 3.1E-20 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 Pfam PF00970 Oxidoreductase FAD-binding domain 106 197 1.3E-16 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 9.3E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 300 308 9.3E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 208 227 9.3E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 233 242 9.3E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 Gene3D G3DSA:2.40.30.10 101 189 1.7E-24 T 28-03-2018 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 8.3E-22 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 8.3E-22 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 8.3E-22 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00410 Phenol hydroxylase reductase family signature 300 308 8.3E-22 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 8.3E-22 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 PRINTS PR00410 Phenol hydroxylase reductase family signature 192 201 8.3E-22 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 81 6.1E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 SUPERFAMILY SSF52343 200 334 1.7E-37 T 28-03-2018 hmeg3_RS17460 4c3a679a6163a5f72a1a189909527883 343 Gene3D G3DSA:3.40.50.80 190 330 1.4E-24 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 499 2.8E-134 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 hmeg3_RS00955 192000e867087f8a580008530e537709 512 Gene3D G3DSA:1.20.1250.20 22 205 8.0E-33 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 5.2E-5 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 5.2E-5 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 5.2E-5 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 211 229 5.2E-5 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 Pfam PF07690 Major Facilitator Superfamily 26 418 3.6E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS00955 192000e867087f8a580008530e537709 512 Gene3D G3DSA:1.20.1250.20 268 511 2.6E-21 T 28-03-2018 hmeg3_RS00955 192000e867087f8a580008530e537709 512 SUPERFAMILY SSF103473 476 504 2.22E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00955 192000e867087f8a580008530e537709 512 SUPERFAMILY SSF103473 257 428 2.22E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS00955 192000e867087f8a580008530e537709 512 SUPERFAMILY SSF103473 22 206 2.22E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS16370 5d1de8eab0a6d3bb4e13ed414b25d1a6 427 Gene3D G3DSA:1.20.1250.20 9 207 6.7E-33 T 28-03-2018 hmeg3_RS16370 5d1de8eab0a6d3bb4e13ed414b25d1a6 427 Gene3D G3DSA:1.20.1250.20 208 408 6.6E-16 T 28-03-2018 hmeg3_RS16370 5d1de8eab0a6d3bb4e13ed414b25d1a6 427 Pfam PF07690 Major Facilitator Superfamily 23 362 4.9E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS16370 5d1de8eab0a6d3bb4e13ed414b25d1a6 427 SUPERFAMILY SSF103473 7 409 4.19E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS22495 720f6f4d19ff04f66362f08b975ade86 135 Gene3D G3DSA:3.10.450.160 24 135 3.8E-26 T 28-03-2018 hmeg3_RS22495 720f6f4d19ff04f66362f08b975ade86 135 Pfam PF11776 Nickel/cobalt transporter regulator 80 130 2.9E-26 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB hmeg3_RS22495 720f6f4d19ff04f66362f08b975ade86 135 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 75 130 7.0E-21 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00184 Neisseria sp. porin signature 152 169 1.7E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00184 Neisseria sp. porin signature 314 338 1.7E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00184 Neisseria sp. porin signature 50 75 1.7E-10 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 Gene3D G3DSA:2.40.160.10 6 384 3.0E-64 T 28-03-2018 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 Pfam PF13609 Gram-negative porin 4 302 4.9E-35 T 28-03-2018 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 248 260 1.7E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 153 164 1.7E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 317 334 1.7E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 92 102 1.7E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 48 59 1.7E-10 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS05055 5ad3572995a113d4d6d8811ac354fc6d 384 SUPERFAMILY SSF56935 11 384 1.54E-76 T 28-03-2018 hmeg3_RS14040 d1765e25aef361bdb91d6a2d4b3a23c2 105 SUPERFAMILY SSF103481 5 102 1.7E-19 T 28-03-2018 hmeg3_RS14040 d1765e25aef361bdb91d6a2d4b3a23c2 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.9E-25 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 hmeg3_RS00760 19410ea3f268ba320c43af9167faaa17 132 SUPERFAMILY SSF52980 23 115 6.03E-18 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 hmeg3_RS00760 19410ea3f268ba320c43af9167faaa17 132 Gene3D G3DSA:3.40.1350.10 23 131 2.5E-34 T 28-03-2018 hmeg3_RS00760 19410ea3f268ba320c43af9167faaa17 132 Pfam PF02021 Uncharacterised protein family UPF0102 24 111 1.4E-25 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 hmeg3_RS00760 19410ea3f268ba320c43af9167faaa17 132 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 18 126 7.0E-31 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 hmeg3_RS00760 19410ea3f268ba320c43af9167faaa17 132 Hamap MF_00048 UPF0102 protein YraN [yraN]. 17 126 22.067 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 hmeg3_RS04860 f3ceff1d6741b7eb46643793bba08f74 154 SUPERFAMILY SSF117856 20 149 3.66E-19 T 28-03-2018 hmeg3_RS04860 f3ceff1d6741b7eb46643793bba08f74 154 Pfam PF03479 Domain of unknown function (DUF296) 30 142 9.3E-13 T 28-03-2018 IPR005175 PPC domain hmeg3_RS04860 f3ceff1d6741b7eb46643793bba08f74 154 Gene3D G3DSA:3.30.1330.80 16 152 3.2E-18 T 28-03-2018 hmeg3_RS09290 042ec481060f361040b0d8d8bfcc7088 521 SUPERFAMILY SSF55073 365 519 2.67E-47 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS09290 042ec481060f361040b0d8d8bfcc7088 521 Gene3D G3DSA:3.30.70.270 354 521 5.8E-50 T 28-03-2018 hmeg3_RS09290 042ec481060f361040b0d8d8bfcc7088 521 SMART SM00267 346 520 9.9E-51 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09290 042ec481060f361040b0d8d8bfcc7088 521 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 362 520 2.0E-46 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS09290 042ec481060f361040b0d8d8bfcc7088 521 Pfam PF00990 Diguanylate cyclase, GGDEF domain 363 516 1.3E-42 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Pfam PF13183 4Fe-4S dicluster domain 593 669 1.4E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Gene3D G3DSA:3.30.465.10 107 303 6.1E-39 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Pfam PF01565 FAD binding domain 55 188 1.4E-36 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 655 666 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 SUPERFAMILY SSF46548 592 682 1.2E-8 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Pfam PF02913 FAD linked oxidases, C-terminal domain 282 531 2.1E-48 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 SUPERFAMILY SSF56176 30 282 4.67E-53 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Gene3D G3DSA:1.10.1060.10 562 689 3.6E-14 T 28-03-2018 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Gene3D G3DSA:3.30.43.10 6 106 9.3E-12 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Pfam PF02754 Cysteine-rich domain 910 981 0.13 T 28-03-2018 IPR004017 Cysteine-rich domain hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 Gene3D G3DSA:1.10.45.10 492 531 1.5E-7 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 hmeg3_RS07745 f23f58c83ba104ea70e2ec7a3b777511 1002 SUPERFAMILY SSF55103 256 532 1.13E-52 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 hmeg3_RS14530 4bc2e0a93623c742543b927fe98044fe 188 TIGRFAM TIGR01841 phasin: phasin family protein 31 116 2.1E-22 T 28-03-2018 IPR010127 Phasin, subfamily 1 hmeg3_RS14530 4bc2e0a93623c742543b927fe98044fe 188 Gene3D G3DSA:1.20.120.20 93 186 9.7E-6 T 28-03-2018 hmeg3_RS14530 4bc2e0a93623c742543b927fe98044fe 188 Pfam PF09361 Phasin protein 6 108 1.8E-26 T 28-03-2018 IPR018968 Phasin hmeg3_RS11925 9b32db23f675c4094843f21261c621f8 257 Pfam PF03988 Repeat of Unknown Function (DUF347) 22 73 4.2E-15 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS11925 9b32db23f675c4094843f21261c621f8 257 Pfam PF03988 Repeat of Unknown Function (DUF347) 77 127 2.2E-10 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS11925 9b32db23f675c4094843f21261c621f8 257 Pfam PF03988 Repeat of Unknown Function (DUF347) 198 252 1.1E-13 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS11925 9b32db23f675c4094843f21261c621f8 257 Pfam PF03988 Repeat of Unknown Function (DUF347) 142 192 2.5E-13 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS09040 123982acf794dc0de45a5b4fe6b27178 211 PIRSF PIRSF006324 1 208 1.3E-52 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS09040 123982acf794dc0de45a5b4fe6b27178 211 Pfam PF01810 LysE type translocator 16 203 7.1E-33 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 Gene3D G3DSA:3.60.15.10 1 245 1.9E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 SMART SM00849 18 206 1.2E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 SUPERFAMILY SSF56281 1 227 5.9E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 82 103 6.2E-9 T 28-03-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 50 68 6.2E-9 T 28-03-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 198 211 6.2E-9 T 28-03-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 hmeg3_RS22225 991347a8e60316b8312cd28f6b25b2c4 257 Pfam PF12706 Beta-lactamase superfamily domain 28 193 3.8E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS08245 0d50335342d3b5a6ecea23fb4919ede9 478 Gene3D G3DSA:1.20.1600.10 32 469 9.9E-85 T 28-03-2018 hmeg3_RS08245 0d50335342d3b5a6ecea23fb4919ede9 478 Pfam PF02321 Outer membrane efflux protein 287 461 6.6E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS08245 0d50335342d3b5a6ecea23fb4919ede9 478 Pfam PF02321 Outer membrane efflux protein 71 253 2.0E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS08245 0d50335342d3b5a6ecea23fb4919ede9 478 SUPERFAMILY SSF56954 15 464 5.23E-91 T 28-03-2018 hmeg3_RS08245 0d50335342d3b5a6ecea23fb4919ede9 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 462 2.3E-87 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS07210 265b8e6277314674fcf35bec8eae3c3b 226 SUPERFAMILY SSF53474 14 224 1.28E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07210 265b8e6277314674fcf35bec8eae3c3b 226 Pfam PF02230 Phospholipase/Carboxylesterase 18 221 2.5E-49 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 hmeg3_RS07210 265b8e6277314674fcf35bec8eae3c3b 226 Gene3D G3DSA:3.40.50.1820 6 223 1.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 SUPERFAMILY SSF103473 2 174 8.37E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 SUPERFAMILY SSF103473 225 439 8.37E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 Gene3D G3DSA:1.20.1250.20 1 175 7.2E-30 T 28-03-2018 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 Gene3D G3DSA:1.20.1250.20 235 447 2.2E-23 T 28-03-2018 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 377 396 4.6E-10 T 28-03-2018 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 105 4.6E-10 T 28-03-2018 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 4.6E-10 T 28-03-2018 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 139 4.6E-10 T 28-03-2018 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 Pfam PF07690 Major Facilitator Superfamily 251 425 2.9E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS14090 c18dfda6ab2970aae8d3cb928a52fb2a 449 Pfam PF07690 Major Facilitator Superfamily 4 222 2.8E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS09530 db76f3513a8a8ad7140783530508882e 168 Gene3D G3DSA:3.40.250.10 42 168 3.2E-21 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS09530 db76f3513a8a8ad7140783530508882e 168 SUPERFAMILY SSF52821 36 167 2.23E-19 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS09530 db76f3513a8a8ad7140783530508882e 168 SMART SM00450 44 151 1.0E-9 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS09530 db76f3513a8a8ad7140783530508882e 168 Pfam PF00581 Rhodanese-like domain 49 143 1.1E-11 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS23790 fc7fd4ffaffd248afd574599f131714c 148 Gene3D G3DSA:3.10.490.10 1 137 1.5E-20 T 28-03-2018 hmeg3_RS23790 fc7fd4ffaffd248afd574599f131714c 148 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 8 116 1.1E-15 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like hmeg3_RS23790 fc7fd4ffaffd248afd574599f131714c 148 SUPERFAMILY SSF110857 5 120 3.14E-22 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like hmeg3_RS14030 3abe7f73fa4d4c22dd3983bb6c89a0b7 251 SUPERFAMILY SSF53474 1 247 1.8E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS14030 3abe7f73fa4d4c22dd3983bb6c89a0b7 251 Pfam PF00561 alpha/beta hydrolase fold 22 134 2.2E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS14030 3abe7f73fa4d4c22dd3983bb6c89a0b7 251 Gene3D G3DSA:3.40.50.1820 1 247 1.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 Pfam PF00890 FAD binding domain 14 409 1.6E-115 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 SUPERFAMILY SSF46977 456 592 9.29E-45 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 394 1.1E-5 T 28-03-2018 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.1E-5 T 28-03-2018 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 SUPERFAMILY SSF56425 241 359 2.09E-44 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 2.8E-244 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 Gene3D G3DSA:1.20.58.100 435 544 1.4E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 466 591 3.3E-39 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 PIRSF PIRSF000171 3 582 3.2E-42 T 28-03-2018 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 Gene3D G3DSA:4.10.80.40 545 592 7.7E-19 T 28-03-2018 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 SUPERFAMILY SSF51905 363 432 6.49E-78 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 SUPERFAMILY SSF51905 6 264 6.49E-78 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 Gene3D G3DSA:3.50.50.60 313 425 1.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 2.1E-286 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 hmeg3_RS08760 92667014f9ef4a9f2489cae8a2104e14 592 Gene3D G3DSA:3.50.50.60 2 297 5.0E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS18315 241e77bf621f39395b0e316d4d833b50 78 SUPERFAMILY SSF143800 2 77 1.73E-30 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS18315 241e77bf621f39395b0e316d4d833b50 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.319 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS18315 241e77bf621f39395b0e316d4d833b50 78 Pfam PF00830 Ribosomal L28 family 3 61 9.2E-27 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS18315 241e77bf621f39395b0e316d4d833b50 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 4.3E-27 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS18315 241e77bf621f39395b0e316d4d833b50 78 Gene3D G3DSA:2.30.170.40 2 75 5.5E-29 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS01105 2a1cbf44ccbbb02451c5e6b7bcf7216a 383 SUPERFAMILY SSF53822 27 379 3.34E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS01105 2a1cbf44ccbbb02451c5e6b7bcf7216a 383 Gene3D G3DSA:3.40.50.2300 155 313 1.9E-29 T 28-03-2018 hmeg3_RS01105 2a1cbf44ccbbb02451c5e6b7bcf7216a 383 Gene3D G3DSA:3.40.50.2300 28 154 1.2E-17 T 28-03-2018 hmeg3_RS01105 2a1cbf44ccbbb02451c5e6b7bcf7216a 383 Pfam PF13458 Periplasmic binding protein 28 368 4.5E-53 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 482 7.4E-57 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 SMART SM00283 267 514 5.5E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 Pfam PF02203 Tar ligand binding domain homologue 2 169 4.8E-18 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 Gene3D G3DSA:1.10.287.950 317 518 3.2E-49 T 28-03-2018 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 Pfam PF00672 HAMP domain 216 261 2.3E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 1.4E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 1.4E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 1.4E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 1.4E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 59 74 1.4E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 1.4E-60 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 SMART SM00304 214 266 6.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 SUPERFAMILY SSF47170 28 179 6.28E-11 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 Gene3D G3DSA:1.20.120.30 23 188 1.2E-21 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS15585 5e540e7d016e48a63e471b966e431871 581 SUPERFAMILY SSF58104 234 515 5.36E-75 T 28-03-2018 hmeg3_RS19420 63d596a5bc2438f8fcbe8e020b513d6b 373 Pfam PF05707 Zonular occludens toxin (Zot) 5 206 5.7E-24 T 28-03-2018 IPR008900 Zona occludens toxin hmeg3_RS19420 63d596a5bc2438f8fcbe8e020b513d6b 373 Gene3D G3DSA:3.40.50.300 2 210 3.2E-4 T 28-03-2018 hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 SMART SM00833 277 369 1.3E-5 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 199 7.0E-39 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 279 367 1.5E-13 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 Gene3D G3DSA:3.40.50.300 4 220 6.3E-31 T 28-03-2018 hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 SUPERFAMILY SSF90002 279 367 3.27E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 Gene3D G3DSA:3.30.1220.10 253 370 7.4E-15 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal hmeg3_RS12395 a7370336eae7bd0ec9edbeb705db3f7b 374 SUPERFAMILY SSF52540 5 202 3.23E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00275 f6bf0bae3bb7e4c11a25bf87ec787406 211 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 182 3.9E-38 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain hmeg3_RS00275 f6bf0bae3bb7e4c11a25bf87ec787406 211 PIRSF PIRSF005624 4 211 7.3E-48 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 hmeg3_RS00275 f6bf0bae3bb7e4c11a25bf87ec787406 211 Gene3D G3DSA:3.40.50.300 8 205 4.4E-18 T 28-03-2018 hmeg3_RS00275 f6bf0bae3bb7e4c11a25bf87ec787406 211 SUPERFAMILY SSF52540 4 201 2.7E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00275 f6bf0bae3bb7e4c11a25bf87ec787406 211 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 10 205 1.7E-103 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 hmeg3_RS00275 f6bf0bae3bb7e4c11a25bf87ec787406 211 Hamap MF_01389 Urease accessory protein UreG [ureG]. 8 206 47.738 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 hmeg3_RS24320 c03597cab80fbdfbe64674e23704a1d2 159 Gene3D G3DSA:3.30.240.20 93 159 2.1E-11 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain hmeg3_RS04705 39de351e51cfd25cfa47fd91a4e83e46 151 SUPERFAMILY SSF82784 1 139 2.62E-38 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS04705 39de351e51cfd25cfa47fd91a4e83e46 151 Gene3D G3DSA:2.20.25.10 1 24 1.1E-16 T 28-03-2018 hmeg3_RS04705 39de351e51cfd25cfa47fd91a4e83e46 151 Gene3D G3DSA:3.30.300.20 25 141 4.7E-27 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS04705 39de351e51cfd25cfa47fd91a4e83e46 151 Pfam PF02566 OsmC-like protein 36 132 4.7E-15 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS12785 77615c823cdae2a67152ef6c7fc6064c 63 Pfam PF14070 Putative motility protein 6 61 3.6E-16 T 28-03-2018 IPR025906 Putative motility protein hmeg3_RS14540 b60252b0de0237d64e2cda72928007ed 276 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 8 219 3.5E-22 T 28-03-2018 hmeg3_RS03500 40371bed9ca237ad0b6abac7737a73fa 212 SUPERFAMILY SSF52317 1 210 1.36E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS03500 40371bed9ca237ad0b6abac7737a73fa 212 PIRSF PIRSF000495 2 212 1.6E-67 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 hmeg3_RS03500 40371bed9ca237ad0b6abac7737a73fa 212 Gene3D G3DSA:3.40.50.880 1 211 1.3E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS03500 40371bed9ca237ad0b6abac7737a73fa 212 Pfam PF00117 Glutamine amidotransferase class-I 6 207 9.1E-15 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS03500 40371bed9ca237ad0b6abac7737a73fa 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 209 1.3E-63 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 hmeg3_RS03500 40371bed9ca237ad0b6abac7737a73fa 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 210 35.03 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 hmeg3_RS11375 533b04e3f8cd8eaaf46de1e28bfad6d1 308 SUPERFAMILY SSF117856 40 178 2.04E-17 T 28-03-2018 hmeg3_RS11375 533b04e3f8cd8eaaf46de1e28bfad6d1 308 Gene3D G3DSA:3.30.1330.80 184 307 8.6E-9 T 28-03-2018 hmeg3_RS11375 533b04e3f8cd8eaaf46de1e28bfad6d1 308 Gene3D G3DSA:3.30.1330.80 30 183 5.9E-17 T 28-03-2018 hmeg3_RS11375 533b04e3f8cd8eaaf46de1e28bfad6d1 308 Pfam PF03479 Domain of unknown function (DUF296) 196 302 2.6E-9 T 28-03-2018 IPR005175 PPC domain hmeg3_RS11375 533b04e3f8cd8eaaf46de1e28bfad6d1 308 SUPERFAMILY SSF117856 192 302 8.37E-16 T 28-03-2018 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 SUPERFAMILY SSF46894 154 218 4.42E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 Pfam PF00072 Response regulator receiver domain 20 128 8.0E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 Gene3D G3DSA:1.10.10.10 157 218 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 SUPERFAMILY SSF52172 17 142 1.31E-14 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 SMART SM00421 155 212 5.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 3.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 Gene3D G3DSA:3.40.50.2300 3 142 2.3E-16 T 28-03-2018 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10190 bc42d88088d193b46ca1f565a10d0604 241 SMART SM00448 18 135 1.4E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 Gene3D G3DSA:3.90.1280.10 236 290 8.8E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 PIRSF PIRSF005261 1 292 2.3E-73 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 Gene3D G3DSA:3.55.30.10 1 179 1.1E-58 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 Pfam PF01430 Hsp33 protein 3 282 9.8E-84 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 Gene3D G3DSA:1.10.287.480 190 234 2.8E-17 T 28-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 SUPERFAMILY SSF64397 3 241 7.85E-63 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 hmeg3_RS14005 a6d14e1a7a03d7ddf3c08b062287e64a 306 SUPERFAMILY SSF118352 235 290 1.7E-16 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 Gene3D G3DSA:1.10.10.10 120 222 4.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 Pfam PF00072 Response regulator receiver domain 3 113 3.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 SUPERFAMILY SSF46894 117 218 3.97E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 SMART SM00862 144 217 5.7E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 SMART SM00448 1 112 4.4E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 9.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 SUPERFAMILY SSF52172 1 124 1.57E-38 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS07115 6c7823cb19dea8e1526192a1260e86b1 222 Gene3D G3DSA:3.40.50.2300 1 119 1.0E-34 T 28-03-2018 hmeg3_RS17910 a212576ba22b0017ab3cb448b9245d33 100 Pfam PF03795 YCII-related domain 1 81 3.7E-14 T 28-03-2018 IPR005545 YCII-related hmeg3_RS17910 a212576ba22b0017ab3cb448b9245d33 100 Gene3D G3DSA:3.30.70.1060 1 85 1.3E-17 T 28-03-2018 hmeg3_RS17910 a212576ba22b0017ab3cb448b9245d33 100 SUPERFAMILY SSF54909 1 83 9.38E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS10165 117badf3283df617b7f2c9c94db3e460 743 Pfam PF01103 Surface antigen 457 629 2.3E-5 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 hmeg3_RS10165 117badf3283df617b7f2c9c94db3e460 743 Gene3D G3DSA:2.40.160.50 368 743 1.9E-21 T 28-03-2018 hmeg3_RS10165 117badf3283df617b7f2c9c94db3e460 743 Gene3D G3DSA:3.40.1090.10 14 278 9.4E-48 T 28-03-2018 hmeg3_RS10165 117badf3283df617b7f2c9c94db3e460 743 SUPERFAMILY SSF52151 129 247 2.56E-54 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS10165 117badf3283df617b7f2c9c94db3e460 743 SUPERFAMILY SSF52151 27 100 2.56E-54 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS10165 117badf3283df617b7f2c9c94db3e460 743 Pfam PF01734 Patatin-like phospholipase 32 223 2.8E-27 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 Gene3D G3DSA:3.30.70.1150 88 159 2.8E-26 T 28-03-2018 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 Pfam PF13710 ACT domain 13 73 1.4E-14 T 28-03-2018 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 2.0E-35 T 28-03-2018 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 SUPERFAMILY SSF55021 1 76 2.7E-21 T 28-03-2018 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 SUPERFAMILY SSF55021 79 162 1.11E-25 T 28-03-2018 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 2.1E-26 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 Gene3D G3DSA:3.30.70.260 1 87 8.7E-24 T 28-03-2018 hmeg3_RS13955 d5dbc756e92381696c3abb58ffb19316 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 6.3E-63 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 hmeg3_RS11230 286e41c585e1333c2a84ef95dd59582a 313 SUPERFAMILY SSF51197 7 285 2.47E-86 T 28-03-2018 hmeg3_RS11230 286e41c585e1333c2a84ef95dd59582a 313 Gene3D G3DSA:3.60.130.10 1 290 1.0E-72 T 28-03-2018 hmeg3_RS11230 286e41c585e1333c2a84ef95dd59582a 313 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 271 3.3E-52 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS02260 d4ec3a6def4b0df7fbc191c73f5d35c3 511 Gene3D G3DSA:3.30.420.10 120 331 8.9E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 hmeg3_RS02260 d4ec3a6def4b0df7fbc191c73f5d35c3 511 Pfam PF00665 Integrase core domain 124 249 3.8E-12 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 hmeg3_RS09640 6ee637223640429d61bbd72a6f64dba2 583 Pfam PF13175 AAA ATPase domain 1 48 2.4E-10 T 28-03-2018 hmeg3_RS09640 6ee637223640429d61bbd72a6f64dba2 583 SUPERFAMILY SSF52540 1 335 2.92E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS09640 6ee637223640429d61bbd72a6f64dba2 583 Gene3D G3DSA:3.40.50.300 1 370 2.0E-23 T 28-03-2018 hmeg3_RS09640 6ee637223640429d61bbd72a6f64dba2 583 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 229 331 1.1E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 hmeg3_RS16060 f77e5d6d1eb3fcf7e9f8531a46766e36 251 SMART SM00893 23 213 1.1E-68 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 hmeg3_RS16060 f77e5d6d1eb3fcf7e9f8531a46766e36 251 SUPERFAMILY SSF52402 1 244 3.42E-86 T 28-03-2018 hmeg3_RS16060 f77e5d6d1eb3fcf7e9f8531a46766e36 251 Gene3D G3DSA:3.40.50.620 1 250 2.9E-89 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS16060 f77e5d6d1eb3fcf7e9f8531a46766e36 251 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 157 177 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 hmeg3_RS16060 f77e5d6d1eb3fcf7e9f8531a46766e36 251 PIRSF PIRSF000090 1 251 4.2E-88 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 hmeg3_RS16060 f77e5d6d1eb3fcf7e9f8531a46766e36 251 Pfam PF01012 Electron transfer flavoprotein domain 29 208 1.1E-45 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 SMART SM00283 265 512 3.8E-94 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 4.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 4.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 4.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 4.3E-57 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 SUPERFAMILY SSF58104 232 513 3.4E-76 T 28-03-2018 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 Gene3D G3DSA:1.20.120.30 22 184 7.6E-17 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 Gene3D G3DSA:1.10.287.950 324 516 1.8E-48 T 28-03-2018 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 Gene3D G3DSA:1.10.287.1060 239 323 0.0052 T 28-03-2018 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 Pfam PF00672 HAMP domain 212 255 1.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 SMART SM00304 212 264 7.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 170 7.5E-23 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS17010 6f9be2fc9731be3c4c0052ae577f82c5 577 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 479 3.0E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS15300 4a5a6cfc860af66ad2b28a25eb1ab8ab 175 Pfam PF06073 Bacterial protein of unknown function (DUF934) 57 163 6.6E-44 T 28-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 hmeg3_RS15300 4a5a6cfc860af66ad2b28a25eb1ab8ab 175 PIRSF PIRSF030820 2 172 1.7E-55 T 28-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 hmeg3_RS01990 aea22a361d1010d0651ceb3fcc4579c4 359 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 327 2.2E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01990 aea22a361d1010d0651ceb3fcc4579c4 359 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 5 355 1.1E-150 T 28-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 hmeg3_RS01990 aea22a361d1010d0651ceb3fcc4579c4 359 SUPERFAMILY SSF51735 5 341 1.3E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01990 aea22a361d1010d0651ceb3fcc4579c4 359 Gene3D G3DSA:3.90.25.10 199 359 2.5E-24 T 28-03-2018 hmeg3_RS01990 aea22a361d1010d0651ceb3fcc4579c4 359 Gene3D G3DSA:3.40.50.720 1 198 3.0E-31 T 28-03-2018 hmeg3_RS20240 e7933ed89ed46bc370ac51932a315232 1131 Pfam PF01841 Transglutaminase-like superfamily 143 246 9.9E-18 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS20240 e7933ed89ed46bc370ac51932a315232 1131 SMART SM00460 172 248 1.7E-21 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS20240 e7933ed89ed46bc370ac51932a315232 1131 Gene3D G3DSA:3.90.260.10 167 272 1.1E-6 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS20240 e7933ed89ed46bc370ac51932a315232 1131 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1129 0.0 T 28-03-2018 IPR018667 Domain of unknown function DUF2126 hmeg3_RS20240 e7933ed89ed46bc370ac51932a315232 1131 SUPERFAMILY SSF54001 8 337 2.8E-76 T 28-03-2018 hmeg3_RS20240 e7933ed89ed46bc370ac51932a315232 1131 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 2.1E-26 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal hmeg3_RS08695 33148b61af30b7af1c49c6f39a2159c7 184 Gene3D G3DSA:1.10.287.500 4 129 2.6E-4 T 28-03-2018 hmeg3_RS08695 33148b61af30b7af1c49c6f39a2159c7 184 SUPERFAMILY SSF75708 4 127 8.63E-6 T 28-03-2018 hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 SUPERFAMILY SSF51735 136 315 2.02E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 SMART SM01002 145 314 4.6E-86 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 SUPERFAMILY SSF52283 1 167 8.33E-49 T 28-03-2018 hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 370 6.7E-73 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 Gene3D G3DSA:3.40.50.720 1 192 1.3E-42 T 28-03-2018 hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 7.4E-41 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 Gene3D G3DSA:3.40.50.720 193 371 5.0E-40 T 28-03-2018 hmeg3_RS19950 b0517b4b539e93ad0e0bece52815a245 371 SMART SM01003 4 136 8.1E-65 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal hmeg3_RS12430 5737df7ad673281472b3f501a7bfd864 242 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 211 4.1E-28 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 hmeg3_RS12430 5737df7ad673281472b3f501a7bfd864 242 Gene3D G3DSA:3.40.1010.10 1 117 5.3E-20 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12430 5737df7ad673281472b3f501a7bfd864 242 Gene3D G3DSA:3.30.950.10 118 226 1.1E-14 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12430 5737df7ad673281472b3f501a7bfd864 242 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 204 3.9E-24 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS12430 5737df7ad673281472b3f501a7bfd864 242 SUPERFAMILY SSF53790 1 219 1.28E-34 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 hmeg3_RS13580 8a045dc8efbeb4c4a23d8f35d1d48301 278 TIGRFAM TIGR02285 TIGR02285: conserved hypothetical protein 13 263 5.2E-43 T 28-03-2018 IPR011972 Conserved hypothetical protein CHP02285 hmeg3_RS13580 8a045dc8efbeb4c4a23d8f35d1d48301 278 Gene3D G3DSA:3.40.190.10 94 197 1.2E-4 T 28-03-2018 hmeg3_RS13580 8a045dc8efbeb4c4a23d8f35d1d48301 278 SUPERFAMILY SSF53850 28 259 4.24E-15 T 28-03-2018 hmeg3_RS10585 c95e34f25f94ba010d2a83a14110991f 251 Gene3D G3DSA:3.40.50.880 31 239 9.8E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10585 c95e34f25f94ba010d2a83a14110991f 251 SUPERFAMILY SSF52317 37 212 2.37E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS10585 c95e34f25f94ba010d2a83a14110991f 251 Pfam PF00117 Glutamine amidotransferase class-I 32 206 3.6E-24 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS18065 ea4bbe92a84e71c4960bdd87503054c1 103 Pfam PF05164 Cell division protein ZapA 5 67 1.4E-19 T 28-03-2018 IPR007838 Cell division protein ZapA-like hmeg3_RS18065 ea4bbe92a84e71c4960bdd87503054c1 103 SUPERFAMILY SSF102829 3 96 1.7E-19 T 28-03-2018 IPR007838 Cell division protein ZapA-like hmeg3_RS14510 6b1fb20b1c68d98fa77e7e2afe0156ca 253 Gene3D G3DSA:3.40.50.150 22 253 9.1E-45 T 28-03-2018 hmeg3_RS14510 6b1fb20b1c68d98fa77e7e2afe0156ca 253 Pfam PF08241 Methyltransferase domain 47 143 8.8E-26 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS14510 6b1fb20b1c68d98fa77e7e2afe0156ca 253 SUPERFAMILY SSF53335 12 241 2.59E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 Pfam PF00990 Diguanylate cyclase, GGDEF domain 114 265 2.9E-24 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 110 268 1.5E-16 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 SMART SM00267 103 270 2.2E-30 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 SMART SM00052 280 525 5.1E-118 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 Pfam PF00563 EAL domain 286 520 8.6E-74 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 SUPERFAMILY SSF55073 119 272 2.38E-26 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 Gene3D G3DSA:3.30.70.270 111 283 7.6E-36 T 28-03-2018 hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 Gene3D G3DSA:3.20.20.450 284 536 5.5E-99 T 28-03-2018 IPR001633 EAL domain hmeg3_RS05435 eff04e6cd488ed575add3a0495ee11cf 541 SUPERFAMILY SSF141868 286 533 5.1E-89 T 28-03-2018 IPR001633 EAL domain hmeg3_RS23120 4f2628144b288c1afd2f5ffd956919c4 288 SUPERFAMILY SSF161098 83 269 1.83E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23120 4f2628144b288c1afd2f5ffd956919c4 288 Gene3D G3DSA:1.10.3720.10 41 284 1.7E-20 T 28-03-2018 hmeg3_RS23120 4f2628144b288c1afd2f5ffd956919c4 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 279 6.6E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14660 b4600ecc9beda8b6b467d1528a0725fe 389 Pfam PF05762 VWA domain containing CoxE-like protein 183 271 4.6E-7 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like hmeg3_RS18800 9330958faba5be23036050573ba0f7de 511 SUPERFAMILY SSF52540 12 378 7.61E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS18800 9330958faba5be23036050573ba0f7de 511 SMART SM00382 22 329 0.0092 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS18800 9330958faba5be23036050573ba0f7de 511 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 509 5.4E-241 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal hmeg3_RS18800 9330958faba5be23036050573ba0f7de 511 Gene3D G3DSA:3.40.50.300 13 410 3.2E-28 T 28-03-2018 hmeg3_RS00650 b7a3b84d501ceacdf7292a5983b175f9 258 Gene3D G3DSA:3.60.10.10 3 257 9.6E-51 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS00650 b7a3b84d501ceacdf7292a5983b175f9 258 SUPERFAMILY SSF56219 3 256 5.89E-75 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS00650 b7a3b84d501ceacdf7292a5983b175f9 258 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 hmeg3_RS00650 b7a3b84d501ceacdf7292a5983b175f9 258 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 254 2.1E-76 T 28-03-2018 hmeg3_RS00650 b7a3b84d501ceacdf7292a5983b175f9 258 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 249 8.2E-18 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase hmeg3_RS00650 b7a3b84d501ceacdf7292a5983b175f9 258 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 256 6.7E-81 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 hmeg3_RS02745 df0cf9c9f046354a49fb7ee9521d611c 328 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 292 7.3E-56 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS02745 df0cf9c9f046354a49fb7ee9521d611c 328 Gene3D G3DSA:3.40.50.720 118 293 1.2E-52 T 28-03-2018 hmeg3_RS02745 df0cf9c9f046354a49fb7ee9521d611c 328 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 323 4.6E-13 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS02745 df0cf9c9f046354a49fb7ee9521d611c 328 SUPERFAMILY SSF52283 1 124 3.4E-18 T 28-03-2018 hmeg3_RS02745 df0cf9c9f046354a49fb7ee9521d611c 328 SUPERFAMILY SSF51735 106 292 6.27E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS02745 df0cf9c9f046354a49fb7ee9521d611c 328 Gene3D G3DSA:3.40.50.720 1 117 1.4E-24 T 28-03-2018 hmeg3_RS15335 e74598d594aceac62048507f689bd701 377 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 374 1.6E-104 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 hmeg3_RS15335 e74598d594aceac62048507f689bd701 377 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 371 5.4E-61 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 Gene3D G3DSA:1.10.3860.10 1 406 1.9E-96 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 SUPERFAMILY SSF118215 11 399 1.31E-99 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 PRINTS PR00173 Glutamate-aspartate symporter signature 144 166 3.4E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 3.4E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 3.4E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 3.4E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 3.4E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS20690 7b5d30188417946c2c0ca8daee6cefd3 416 Pfam PF00375 Sodium:dicarboxylate symporter family 11 398 2.5E-93 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 143 23.917 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 142 2.7E-38 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 142 5.4E-43 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 SUPERFAMILY SSF81330 12 138 9.42E-34 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 91 99 2.7E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 2.7E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS03560 ccc7f35131478495c51d0442009f1e4a 143 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 100 109 2.7E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 hmeg3_RS10970 7ad8db1a062ff32ef1b120fce72ba7f3 424 Pfam PF13416 Bacterial extracellular solute-binding protein 50 359 4.6E-47 T 28-03-2018 hmeg3_RS10970 7ad8db1a062ff32ef1b120fce72ba7f3 424 SUPERFAMILY SSF53850 30 416 2.23E-80 T 28-03-2018 hmeg3_RS10970 7ad8db1a062ff32ef1b120fce72ba7f3 424 Gene3D G3DSA:3.40.190.10 145 420 1.1E-52 T 28-03-2018 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 211 604 3.5E-112 T 28-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 2 600 19.558 T 28-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 SUPERFAMILY SSF51905 211 427 2.52E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 SUPERFAMILY SSF51905 520 602 2.52E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 Gene3D G3DSA:3.40.50.150 9 199 5.6E-19 T 28-03-2018 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 Gene3D G3DSA:3.50.50.60 200 607 6.0E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS23275 2c73069cb6147be8e7fece905da9252b 607 Pfam PF01266 FAD dependent oxidoreductase 212 574 9.6E-38 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS00935 08437daae83314094efac6ace798e58b 292 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 41 272 2.4E-51 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 hmeg3_RS07485 152ef619d6da8a5d8f76d78e6ff840ff 270 SUPERFAMILY SSF50494 16 156 2.42E-11 T 28-03-2018 IPR009003 Peptidase S1, PA clan hmeg3_RS07485 152ef619d6da8a5d8f76d78e6ff840ff 270 SUPERFAMILY SSF50494 200 264 2.42E-11 T 28-03-2018 IPR009003 Peptidase S1, PA clan hmeg3_RS07485 152ef619d6da8a5d8f76d78e6ff840ff 270 Gene3D G3DSA:2.40.10.10 133 262 0.0015 T 28-03-2018 hmeg3_RS05955 10c84fce43597f46659836ae072467b6 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 12 347 1.4E-92 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 hmeg3_RS05955 10c84fce43597f46659836ae072467b6 371 Gene3D G3DSA:3.20.20.70 1 371 1.0E-127 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS05955 10c84fce43597f46659836ae072467b6 371 SUPERFAMILY SSF51395 8 368 1.31E-122 T 28-03-2018 hmeg3_RS04070 bfaf7e0d363e648807c3a90cb8583190 254 SUPERFAMILY SSF51197 3 241 2.54E-55 T 28-03-2018 hmeg3_RS04070 bfaf7e0d363e648807c3a90cb8583190 254 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 13 225 3.2E-36 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase hmeg3_RS04070 bfaf7e0d363e648807c3a90cb8583190 254 Gene3D G3DSA:2.60.120.620 2 245 5.6E-42 T 28-03-2018 hmeg3_RS16015 ad24b9dd785ece7eea5f493d682ee817 318 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 318 61.195 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 hmeg3_RS16015 ad24b9dd785ece7eea5f493d682ee817 318 Pfam PF03186 CobD/Cbib protein 25 256 2.7E-23 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 hmeg3_RS10480 36b59aecf113c3cdc112be4c7a53436c 166 SMART SM00972 105 163 1.9E-20 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS10480 36b59aecf113c3cdc112be4c7a53436c 166 Pfam PF05229 Spore Coat Protein U domain 32 163 1.4E-32 T 28-03-2018 IPR007893 Spore coat protein U hmeg3_RS16755 8355add7cb79103950d127f48bc37f64 60 SUPERFAMILY SSF57829 2 55 1.46E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 hmeg3_RS16755 8355add7cb79103950d127f48bc37f64 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.855 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16755 8355add7cb79103950d127f48bc37f64 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 9.2E-20 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS16755 8355add7cb79103950d127f48bc37f64 60 Pfam PF01783 Ribosomal L32p protein family 2 55 5.6E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 Pfam PF04452 RNA methyltransferase 18 236 2.2E-66 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 Gene3D G3DSA:2.40.240.20 1 70 8.5E-22 T 28-03-2018 hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 SUPERFAMILY SSF88697 1 66 1.99E-16 T 28-03-2018 IPR015947 PUA-like domain hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 SUPERFAMILY SSF75217 72 241 6.98E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 PIRSF PIRSF015601 1 241 2.3E-58 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 239 1.6E-55 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS06775 09d9f93c94fc702926b5ac008322d367 241 Gene3D G3DSA:3.40.1280.10 71 241 1.4E-55 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS01950 d2c09bec240796a777380534a72048b8 261 Pfam PF00535 Glycosyl transferase family 2 10 107 8.3E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS01950 d2c09bec240796a777380534a72048b8 261 SUPERFAMILY SSF53448 7 228 1.5E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS01950 d2c09bec240796a777380534a72048b8 261 Gene3D G3DSA:3.90.550.10 3 250 2.3E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS15675 4e080110e4d03fdb41ea25d0ad83951c 311 PIRSF PIRSF028235 1 311 8.6E-160 T 28-03-2018 IPR016877 Uncharacterised conserved protein UCP028235 hmeg3_RS15675 4e080110e4d03fdb41ea25d0ad83951c 311 SUPERFAMILY SSF64182 5 308 2.3E-11 T 28-03-2018 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 SUPERFAMILY SSF51726 5 357 2.09E-112 T 28-03-2018 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 25 34 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 9 354 48.106 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 Gene3D G3DSA:3.20.20.210 1 359 1.8E-101 T 28-03-2018 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 144 160 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 12 352 6.2E-125 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 hmeg3_RS02480 848e2e3d7aca7a199d3b026e67126802 359 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 352 1.0E-130 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 hmeg3_RS12500 1345721bc91c34114d9fb1112845fac8 314 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 271 2.5E-110 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 hmeg3_RS12500 1345721bc91c34114d9fb1112845fac8 314 Pfam PF00483 Nucleotidyl transferase 11 271 5.3E-27 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 hmeg3_RS12500 1345721bc91c34114d9fb1112845fac8 314 Gene3D G3DSA:3.90.550.10 1 298 5.3E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS12500 1345721bc91c34114d9fb1112845fac8 314 SUPERFAMILY SSF53448 1 275 1.44E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 PIRSF PIRSF000005 8 222 2.3E-64 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 SUPERFAMILY SSF46626 38 121 1.75E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 PRINTS PR00605 Class IC cytochrome C signature 56 67 3.9E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 PRINTS PR00605 Class IC cytochrome C signature 196 218 3.9E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 Gene3D G3DSA:1.10.760.10 18 123 5.0E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 Gene3D G3DSA:1.10.760.10 124 221 4.2E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 SUPERFAMILY SSF46626 134 220 1.6E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 Pfam PF00034 Cytochrome c 154 222 1.4E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS22640 f7152ec6cdd43ef02fda46b8249677b1 222 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 39 120 2.1E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS04915 2641b1926809c05d2564a90203565b85 214 SUPERFAMILY SSF52833 2 85 2.61E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS04915 2641b1926809c05d2564a90203565b85 214 Gene3D G3DSA:1.20.1050.10 91 212 7.6E-11 T 28-03-2018 hmeg3_RS04915 2641b1926809c05d2564a90203565b85 214 Gene3D G3DSA:3.40.30.10 1 90 7.2E-13 T 28-03-2018 hmeg3_RS04915 2641b1926809c05d2564a90203565b85 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 71 7.7E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS04915 2641b1926809c05d2564a90203565b85 214 SUPERFAMILY SSF47616 71 203 1.47E-5 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS18870 a9427ace6d4e11f78704b97aa538a740 75 Pfam PF11755 Protein of unknown function (DUF3311) 7 62 9.9E-17 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 SUPERFAMILY SSF51735 8 241 1.51E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 Gene3D G3DSA:3.40.50.720 5 49 5.3E-9 T 28-03-2018 hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 Gene3D G3DSA:3.40.50.720 50 244 2.4E-58 T 28-03-2018 hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 240 3.6E-53 T 28-03-2018 hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 5.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS20535 4b3906cb205f6399e62a8c8c7e02fba8 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 5.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17165 94ff9fd44aec13a94ca6e85765654e6f 292 SUPERFAMILY SSF53474 5 291 2.55E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS17165 94ff9fd44aec13a94ca6e85765654e6f 292 Gene3D G3DSA:3.40.50.1820 2 289 2.1E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS17165 94ff9fd44aec13a94ca6e85765654e6f 292 Pfam PF12697 Alpha/beta hydrolase family 29 283 1.5E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS17165 94ff9fd44aec13a94ca6e85765654e6f 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.4E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS17165 94ff9fd44aec13a94ca6e85765654e6f 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.4E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS17165 94ff9fd44aec13a94ca6e85765654e6f 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.4E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS23610 5c38de5e9ab7fe32df714867487dce29 483 Pfam PF00171 Aldehyde dehydrogenase family 17 472 4.4E-145 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS23610 5c38de5e9ab7fe32df714867487dce29 483 Gene3D G3DSA:3.40.309.10 269 456 6.6E-66 T 28-03-2018 hmeg3_RS23610 5c38de5e9ab7fe32df714867487dce29 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS23610 5c38de5e9ab7fe32df714867487dce29 483 SUPERFAMILY SSF53720 4 476 4.19E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS23610 5c38de5e9ab7fe32df714867487dce29 483 Gene3D G3DSA:3.40.605.10 1 268 8.1E-82 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.3E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 Gene3D G3DSA:3.40.50.720 49 257 6.9E-51 T 28-03-2018 hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 Gene3D G3DSA:3.40.50.720 1 48 5.0E-8 T 28-03-2018 hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 SUPERFAMILY SSF51735 6 252 4.32E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 7.8E-49 T 28-03-2018 hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS21070 afad86ae55ac3140e64fa0c67367625f 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS16270 a55bff83d24f45aba48a404030531886 231 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 125 191 2.1E-5 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16270 a55bff83d24f45aba48a404030531886 231 Gene3D G3DSA:3.90.470.20 17 133 2.9E-21 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16270 a55bff83d24f45aba48a404030531886 231 SUPERFAMILY SSF56214 125 197 2.88E-8 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16270 a55bff83d24f45aba48a404030531886 231 Gene3D G3DSA:3.90.470.20 134 208 4.2E-5 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS16270 a55bff83d24f45aba48a404030531886 231 SUPERFAMILY SSF56214 29 116 4.06E-16 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 hmeg3_RS13675 faee96cfabef758c33a4aee6ba9ccf40 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS13675 faee96cfabef758c33a4aee6ba9ccf40 242 SUPERFAMILY SSF52540 2 236 2.22E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS13675 faee96cfabef758c33a4aee6ba9ccf40 242 SMART SM00382 26 217 1.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS13675 faee96cfabef758c33a4aee6ba9ccf40 242 Pfam PF00005 ABC transporter 17 166 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS13675 faee96cfabef758c33a4aee6ba9ccf40 242 Gene3D G3DSA:3.40.50.300 1 240 1.9E-53 T 28-03-2018 hmeg3_RS13675 faee96cfabef758c33a4aee6ba9ccf40 242 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 237 5.1E-5 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS02320 06531de3ca5119075ef723ef629591a5 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 303 3.8E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02320 06531de3ca5119075ef723ef629591a5 314 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 13 305 4.1E-87 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 hmeg3_RS02320 06531de3ca5119075ef723ef629591a5 314 SUPERFAMILY SSF161098 33 299 1.83E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02320 06531de3ca5119075ef723ef629591a5 314 Gene3D G3DSA:1.10.3720.10 3 301 1.1E-29 T 28-03-2018 hmeg3_RS20435 0b4d61051a16ad02a98b0751f0b914df 231 Pfam PF01618 MotA/TolQ/ExbB proton channel family 106 205 1.3E-35 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 Gene3D G3DSA:3.40.250.10 157 286 1.3E-22 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 Pfam PF00581 Rhodanese-like domain 163 274 7.1E-10 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 Pfam PF00581 Rhodanese-like domain 8 133 9.1E-16 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 Gene3D G3DSA:3.40.250.10 1 156 1.1E-30 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 SUPERFAMILY SSF52821 2 147 1.44E-38 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 SMART SM00450 160 278 2.0E-10 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 SMART SM00450 7 137 1.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 SUPERFAMILY SSF52821 163 285 3.54E-32 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS04790 65d519dc0e122aedd7c1766f558b9686 286 ProSitePatterns PS00683 Rhodanese C-terminal signature. 262 272 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 hmeg3_RS04020 e42a35a06eaf3148687763cc8d640e16 117 SUPERFAMILY SSF69754 1 102 2.88E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 hmeg3_RS04020 e42a35a06eaf3148687763cc8d640e16 117 Gene3D G3DSA:3.30.160.100 1 104 6.7E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 hmeg3_RS04020 e42a35a06eaf3148687763cc8d640e16 117 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 1.2E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 hmeg3_RS04020 e42a35a06eaf3148687763cc8d640e16 117 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 97 1.4E-25 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 hmeg3_RS18135 a41e6f145335aa7e2e233490d73526fa 124 Pfam PF04241 Protein of unknown function (DUF423) 20 106 1.1E-29 T 28-03-2018 IPR006696 Protein of unknown function DUF423 hmeg3_RS21045 4433243461f6c7adc32d746b9e07977a 313 Gene3D G3DSA:3.40.50.2300 147 312 1.8E-37 T 28-03-2018 hmeg3_RS21045 4433243461f6c7adc32d746b9e07977a 313 Gene3D G3DSA:3.40.50.2300 20 146 3.1E-22 T 28-03-2018 hmeg3_RS21045 4433243461f6c7adc32d746b9e07977a 313 SUPERFAMILY SSF53822 30 311 1.13E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS21045 4433243461f6c7adc32d746b9e07977a 313 Pfam PF13407 Periplasmic binding protein domain 31 285 6.8E-56 T 28-03-2018 IPR025997 Periplasmic binding protein hmeg3_RS19425 a433f7da4cd6c5d1c976f058546aedf4 95 Pfam PF10734 Protein of unknown function (DUF2523) 12 88 1.0E-10 T 28-03-2018 IPR019670 Protein of unkown function DUF2523 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 Gene3D G3DSA:3.40.50.300 327 608 5.9E-74 T 28-03-2018 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 Gene3D G3DSA:3.40.50.300 17 326 2.0E-65 T 28-03-2018 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 SUPERFAMILY SSF52540 20 278 2.11E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 SMART SM00382 364 562 8.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 SMART SM00382 49 257 1.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 SUPERFAMILY SSF52540 329 576 1.3E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 556 592 5.6E-9 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 290 2.2E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 Pfam PF00005 ABC transporter 41 207 6.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS16300 619aca1c4086108863040cbd073419d9 633 Pfam PF00005 ABC transporter 356 503 6.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS22630 bae451984d30a062bcb31db0823ec9ae 383 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 144 381 2.1E-74 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 hmeg3_RS22630 bae451984d30a062bcb31db0823ec9ae 383 Pfam PF01578 Cytochrome C assembly protein 174 378 2.2E-50 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 hmeg3_RS16595 8963daa4d94158c73ce6641ca490703d 205 Gene3D G3DSA:3.40.1550.10 3 199 1.3E-46 T 28-03-2018 IPR028976 CheC-like domain hmeg3_RS16595 8963daa4d94158c73ce6641ca490703d 205 SUPERFAMILY SSF103039 3 198 3.92E-43 T 28-03-2018 IPR028976 CheC-like domain hmeg3_RS16595 8963daa4d94158c73ce6641ca490703d 205 Pfam PF13690 Chemotaxis phosphatase CheX 66 151 1.4E-6 T 28-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain hmeg3_RS18470 f9ec39d55e44bc02698e244e0cd58795 217 Gene3D G3DSA:3.40.50.850 4 202 3.4E-35 T 28-03-2018 hmeg3_RS18470 f9ec39d55e44bc02698e244e0cd58795 217 Pfam PF00857 Isochorismatase family 19 169 9.5E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS18470 f9ec39d55e44bc02698e244e0cd58795 217 SUPERFAMILY SSF52499 11 210 2.88E-46 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS18780 2bc73be42b24daf0edba743313f741bd 230 Pfam PF13590 Domain of unknown function (DUF4136) 27 193 3.1E-16 T 28-03-2018 IPR025411 Domain of unknown function DUF4136 hmeg3_RS01940 119603b8667391b42916b89c6b28856e 172 Gene3D G3DSA:3.40.50.150 49 163 9.3E-4 T 28-03-2018 hmeg3_RS01940 119603b8667391b42916b89c6b28856e 172 SUPERFAMILY SSF53335 67 156 3.57E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS12510 4ef21c09770970fa0e338fef7835408e 253 Pfam PF12146 Serine aminopeptidase, S33 62 230 1.0E-9 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS12510 4ef21c09770970fa0e338fef7835408e 253 SUPERFAMILY SSF53474 3 243 9.54E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12510 4ef21c09770970fa0e338fef7835408e 253 Gene3D G3DSA:3.40.50.1820 2 248 2.2E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 SUPERFAMILY SSF56935 24 361 3.66E-66 T 28-03-2018 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 Pfam PF13609 Gram-negative porin 9 327 6.1E-44 T 28-03-2018 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00184 Neisseria sp. porin signature 157 174 1.9E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00184 Neisseria sp. porin signature 58 83 1.9E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00184 Neisseria sp. porin signature 187 204 1.9E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00184 Neisseria sp. porin signature 299 323 1.9E-11 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 Gene3D G3DSA:2.40.160.10 12 361 9.7E-63 T 28-03-2018 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 56 67 8.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 186 198 8.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 158 169 8.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 269 286 8.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS19170 51c00deef40e34942d220692ea9847b2 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 100 110 8.3E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.117 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 SUPERFAMILY SSF47729 1 91 1.16E-29 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 Gene3D G3DSA:4.10.520.10 1 94 1.2E-30 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.7E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.7E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.7E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.3E-29 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 5.0E-40 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 hmeg3_RS17960 dc112b13d41c0d8e91169a56a7611de1 101 SMART SM00411 1 91 1.4E-40 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 hmeg3_RS14640 bf9c8c27f0c1a20a891580f277f366f2 104 SUPERFAMILY SSF46626 26 102 1.89E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS14640 bf9c8c27f0c1a20a891580f277f366f2 104 Gene3D G3DSA:1.10.760.10 9 103 5.9E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS14640 bf9c8c27f0c1a20a891580f277f366f2 104 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 31 99 4.2E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS11800 1f7fa973a7377fae02da0f65ef8c84e2 98 Gene3D G3DSA:3.30.70.1060 1 93 7.4E-12 T 28-03-2018 hmeg3_RS11800 1f7fa973a7377fae02da0f65ef8c84e2 98 Pfam PF03795 YCII-related domain 8 89 7.9E-7 T 28-03-2018 IPR005545 YCII-related hmeg3_RS11800 1f7fa973a7377fae02da0f65ef8c84e2 98 SUPERFAMILY SSF54909 3 91 9.92E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 Pfam PF13353 4Fe-4S single cluster domain 24 149 2.3E-6 T 28-03-2018 hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 SUPERFAMILY SSF102114 11 335 1.18E-65 T 28-03-2018 hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 PIRSF PIRSF037420 7 370 8.2E-66 T 28-03-2018 hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 Gene3D G3DSA:3.20.20.70 8 376 5.6E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 Pfam PF04055 Radical SAM superfamily 26 173 3.0E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 262 352 2.5E-14 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain hmeg3_RS13070 0330e95af8de0099b00938fd5ff27dcb 393 Pfam PF13186 Iron-sulfur cluster-binding domain 262 325 2.0E-6 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain hmeg3_RS03270 3767d106ef8c52038272373e37f035fe 253 SUPERFAMILY SSF48695 19 83 6.98E-5 T 28-03-2018 IPR011031 Multihaem cytochrome hmeg3_RS03270 3767d106ef8c52038272373e37f035fe 253 SUPERFAMILY SSF53271 71 251 5.38E-27 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS03270 3767d106ef8c52038272373e37f035fe 253 Gene3D G3DSA:3.40.50.2020 72 253 4.4E-21 T 28-03-2018 hmeg3_RS03270 3767d106ef8c52038272373e37f035fe 253 Pfam PF00156 Phosphoribosyl transferase domain 155 248 9.1E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 hmeg3_RS18145 ecca67131c10090b51d7114f802618e7 503 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18145 ecca67131c10090b51d7114f802618e7 503 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18145 ecca67131c10090b51d7114f802618e7 503 SUPERFAMILY SSF53720 8 490 2.09E-159 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18145 ecca67131c10090b51d7114f802618e7 503 Gene3D G3DSA:3.40.309.10 281 473 1.5E-70 T 28-03-2018 hmeg3_RS18145 ecca67131c10090b51d7114f802618e7 503 Gene3D G3DSA:3.40.605.10 18 280 1.8E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS18145 ecca67131c10090b51d7114f802618e7 503 Pfam PF00171 Aldehyde dehydrogenase family 33 488 7.2E-166 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS10230 c5728ee90353ccd97975d290ba0e111c 295 SUPERFAMILY SSF51197 5 271 1.92E-38 T 28-03-2018 hmeg3_RS10230 c5728ee90353ccd97975d290ba0e111c 295 Pfam PF08007 Cupin superfamily protein 9 285 7.6E-41 T 28-03-2018 IPR003347 JmjC domain hmeg3_RS10230 c5728ee90353ccd97975d290ba0e111c 295 SMART SM00558 92 230 0.0013 T 28-03-2018 IPR003347 JmjC domain hmeg3_RS10230 c5728ee90353ccd97975d290ba0e111c 295 Gene3D G3DSA:2.60.120.650 6 222 8.8E-19 T 28-03-2018 hmeg3_RS21955 62d7fce36bb54645a79a396a41422b4d 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.4E-29 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 hmeg3_RS21955 62d7fce36bb54645a79a396a41422b4d 106 SUPERFAMILY SSF103481 5 102 3.92E-20 T 28-03-2018 hmeg3_RS07380 1958aac0b1362617213559d7b8f995f4 194 Pfam PF04752 ChaC-like protein 21 183 1.3E-51 T 28-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 hmeg3_RS07380 1958aac0b1362617213559d7b8f995f4 194 Gene3D G3DSA:3.10.490.10 5 188 5.1E-39 T 28-03-2018 hmeg3_RS07380 1958aac0b1362617213559d7b8f995f4 194 SUPERFAMILY SSF110857 21 129 2.35E-12 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like hmeg3_RS03265 e27e207499e9ff009eeb7dadf28d9c34 160 Gene3D G3DSA:3.40.1280.10 1 160 7.6E-39 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal hmeg3_RS03265 e27e207499e9ff009eeb7dadf28d9c34 160 PIRSF PIRSF029256 1 160 5.3E-64 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 hmeg3_RS03265 e27e207499e9ff009eeb7dadf28d9c34 160 SUPERFAMILY SSF75217 2 158 1.64E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases hmeg3_RS03265 e27e207499e9ff009eeb7dadf28d9c34 160 Pfam PF00588 SpoU rRNA Methylase family 2 148 1.3E-31 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 hmeg3_RS03265 e27e207499e9ff009eeb7dadf28d9c34 160 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 2 158 1.1E-57 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 hmeg3_RS03265 e27e207499e9ff009eeb7dadf28d9c34 160 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 157 33.866 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 hmeg3_RS09700 5c46ff536698847998787a0796b74dbe 223 Gene3D G3DSA:3.40.1800.10 16 97 1.0E-5 T 28-03-2018 hmeg3_RS01125 b27945530963dbae2184379a210e60e0 633 Gene3D G3DSA:3.40.50.980 221 388 1.8E-22 T 28-03-2018 hmeg3_RS01125 b27945530963dbae2184379a210e60e0 633 Gene3D G3DSA:3.40.50.980 40 220 1.6E-21 T 28-03-2018 hmeg3_RS01125 b27945530963dbae2184379a210e60e0 633 Gene3D G3DSA:2.30.38.10 389 466 1.1E-12 T 28-03-2018 hmeg3_RS01125 b27945530963dbae2184379a210e60e0 633 Pfam PF00501 AMP-binding enzyme 48 454 6.6E-57 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 hmeg3_RS01125 b27945530963dbae2184379a210e60e0 633 SUPERFAMILY SSF56801 14 603 5.89E-74 T 28-03-2018 hmeg3_RS17830 6d4343cae380a412eb0e470c88a532bc 270 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 263 19.002 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 hmeg3_RS17830 6d4343cae380a412eb0e470c88a532bc 270 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 hmeg3_RS17830 6d4343cae380a412eb0e470c88a532bc 270 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 5 264 3.7E-76 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 hmeg3_RS17830 6d4343cae380a412eb0e470c88a532bc 270 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 257 8.5E-74 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 hmeg3_RS19345 aaf65af30a7f8af9b69f34b9f19d877f 225 Pfam PF03737 Aldolase/RraA 27 173 3.9E-40 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein hmeg3_RS19345 aaf65af30a7f8af9b69f34b9f19d877f 225 SUPERFAMILY SSF89562 23 184 9.94E-50 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein hmeg3_RS19345 aaf65af30a7f8af9b69f34b9f19d877f 225 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 5 225 2.0E-101 T 28-03-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 hmeg3_RS19345 aaf65af30a7f8af9b69f34b9f19d877f 225 Gene3D G3DSA:3.50.30.40 19 197 1.2E-49 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein hmeg3_RS06255 cb56a8a32be0d08863489b5e058d9ce2 71 Gene3D G3DSA:2.60.40.1180 1 70 2.5E-12 T 28-03-2018 hmeg3_RS06255 cb56a8a32be0d08863489b5e058d9ce2 71 Pfam PF08238 Sel1 repeat 23 58 1.5E-8 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS06255 cb56a8a32be0d08863489b5e058d9ce2 71 SUPERFAMILY SSF81901 16 62 1.18E-9 T 28-03-2018 hmeg3_RS06255 cb56a8a32be0d08863489b5e058d9ce2 71 SMART SM00671 22 58 6.1E-7 T 28-03-2018 IPR006597 Sel1-like repeat hmeg3_RS04510 8e27b74725f4803c9346eb52ae1de94b 182 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 44 181 3.7E-32 T 28-03-2018 IPR018550 Lipid A 3-O-deacylase-related hmeg3_RS04510 8e27b74725f4803c9346eb52ae1de94b 182 Gene3D G3DSA:2.40.160.20 28 182 1.4E-31 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS04510 8e27b74725f4803c9346eb52ae1de94b 182 SUPERFAMILY SSF56925 53 182 1.54E-6 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS04510 8e27b74725f4803c9346eb52ae1de94b 182 PIRSF PIRSF029681 1 182 2.2E-45 T 28-03-2018 IPR018550 Lipid A 3-O-deacylase-related hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 Pfam PF00990 Diguanylate cyclase, GGDEF domain 402 561 1.7E-50 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 SUPERFAMILY SSF55073 406 565 1.96E-48 T 28-03-2018 IPR029787 Nucleotide cyclase hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 Gene3D G3DSA:3.30.70.270 394 572 1.7E-57 T 28-03-2018 hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 Gene3D G3DSA:3.30.450.20 171 304 6.1E-17 T 28-03-2018 hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 Pfam PF02743 Cache domain 59 287 8.0E-21 T 28-03-2018 IPR033479 Double Cache domain 1 hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 SUPERFAMILY SSF158472 325 374 1.44E-7 T 28-03-2018 hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 SMART SM00304 325 377 1.1E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 397 564 2.2E-53 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS00410 73711a392681bd27fe224a39f35d27a4 576 SMART SM00267 390 565 1.8E-66 T 28-03-2018 IPR000160 GGDEF domain hmeg3_RS18235 a88b7dd21028d29829ce8ded5cdc9226 105 Pfam PF04972 BON domain 38 104 1.6E-21 T 28-03-2018 IPR007055 BON domain hmeg3_RS18235 a88b7dd21028d29829ce8ded5cdc9226 105 SMART SM00749 43 105 5.7E-8 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS23805 3775c4c312a93606ab3b7575d262a279 122 Gene3D G3DSA:1.10.10.60 4 32 2.7E-11 T 28-03-2018 hmeg3_RS23805 3775c4c312a93606ab3b7575d262a279 122 Gene3D G3DSA:1.10.260.40 33 112 1.5E-7 T 28-03-2018 hmeg3_RS23805 3775c4c312a93606ab3b7575d262a279 122 Pfam PF13384 Homeodomain-like domain 15 40 5.9E-7 T 28-03-2018 hmeg3_RS06295 d9bf3f149a5851739197a3ef32010202 123 SUPERFAMILY SSF51316 3 110 5.44E-33 T 28-03-2018 IPR011057 Mss4-like hmeg3_RS06295 d9bf3f149a5851739197a3ef32010202 123 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 28 108 2.8E-10 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 hmeg3_RS06295 d9bf3f149a5851739197a3ef32010202 123 Gene3D G3DSA:3.90.1590.10 2 116 2.2E-27 T 28-03-2018 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 SUPERFAMILY SSF46785 1 84 3.06E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 SUPERFAMILY SSF53850 91 307 5.61E-18 T 28-03-2018 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 Pfam PF03466 LysR substrate binding domain 91 303 1.4E-19 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 Gene3D G3DSA:3.40.190.10 88 185 3.2E-6 T 28-03-2018 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 Gene3D G3DSA:3.40.190.10 186 278 3.0E-9 T 28-03-2018 hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 Gene3D G3DSA:1.10.10.10 1 83 1.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24400 c9da1e00ae08249ac673b6a9cad1445a 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.2E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS12295 334ba019beebe930f53d72a6fe0e4f48 212 SUPERFAMILY SSF55154 1 205 1.8E-38 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 hmeg3_RS12295 334ba019beebe930f53d72a6fe0e4f48 212 Gene3D G3DSA:2.40.320.10 1 206 7.3E-39 T 28-03-2018 hmeg3_RS12295 334ba019beebe930f53d72a6fe0e4f48 212 SMART SM01118 1 207 6.4E-34 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 hmeg3_RS12295 334ba019beebe930f53d72a6fe0e4f48 212 Pfam PF01928 CYTH domain 2 200 5.4E-25 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 hmeg3_RS03735 45f40751d0ccb2b99c7e4f7e33bc28ff 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03735 45f40751d0ccb2b99c7e4f7e33bc28ff 493 Gene3D G3DSA:3.40.309.10 279 474 3.8E-73 T 28-03-2018 hmeg3_RS03735 45f40751d0ccb2b99c7e4f7e33bc28ff 493 SUPERFAMILY SSF53720 6 491 6.02E-169 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03735 45f40751d0ccb2b99c7e4f7e33bc28ff 493 Gene3D G3DSA:3.40.605.10 10 278 8.1E-101 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS03735 45f40751d0ccb2b99c7e4f7e33bc28ff 493 Pfam PF00171 Aldehyde dehydrogenase family 22 488 1.3E-169 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Gene3D G3DSA:2.60.40.10 876 1007 3.3E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Pfam PF00207 Alpha-2-macroglobulin family 1262 1348 8.4E-13 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Gene3D G3DSA:2.60.40.10 1151 1310 9.1E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 506 619 1.5E-27 T 28-03-2018 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Gene3D G3DSA:1.50.10.20 1489 1732 8.3E-7 T 28-03-2018 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 SMART SM01360 1260 1350 3.2E-22 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Pfam PF01835 MG2 domain 626 746 5.2E-20 T 28-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Gene3D G3DSA:2.60.40.10 1312 1420 1.8E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 SMART SM01359 1023 1202 6.3E-45 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 hmeg3_RS08945 d99a83d02f31a68ec7732f4f9df74e05 1944 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1023 1202 1.7E-20 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 hmeg3_RS19555 c6d09a0c7412e831eaae52bdec8e3786 260 Gene3D G3DSA:3.90.850.10 1 260 2.9E-49 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS19555 c6d09a0c7412e831eaae52bdec8e3786 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 255 1.2E-10 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS19555 c6d09a0c7412e831eaae52bdec8e3786 260 SUPERFAMILY SSF56529 4 258 1.7E-77 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS06870 ef3b83e83e136c1787f9c6f866ee7a8d 132 Gene3D G3DSA:3.10.180.10 1 20 0.071 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS06870 ef3b83e83e136c1787f9c6f866ee7a8d 132 SUPERFAMILY SSF54593 2 131 4.03E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS06870 ef3b83e83e136c1787f9c6f866ee7a8d 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 126 1.0E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS06870 ef3b83e83e136c1787f9c6f866ee7a8d 132 Gene3D G3DSA:3.10.180.10 21 132 2.9E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS06635 06c76f1dade6deba90dcce3d872f5174 104 Gene3D G3DSA:3.30.1390.10 11 103 7.9E-34 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like hmeg3_RS06635 06c76f1dade6deba90dcce3d872f5174 104 SUPERFAMILY SSF54736 19 103 1.05E-31 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like hmeg3_RS06635 06c76f1dade6deba90dcce3d872f5174 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 99 28.03 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS hmeg3_RS06635 06c76f1dade6deba90dcce3d872f5174 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 21 99 1.4E-33 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 hmeg3_RS15175 a8f66ca9d9267f9b2e7150424fd659e8 142 Pfam PF14347 Domain of unknown function (DUF4399) 53 142 2.7E-37 T 28-03-2018 IPR025512 Domain of unknown function DUF4399 hmeg3_RS14080 c574da6f6339614647c5e68f6b27a447 237 Gene3D G3DSA:1.10.3720.10 5 235 1.8E-28 T 28-03-2018 hmeg3_RS14080 c574da6f6339614647c5e68f6b27a447 237 SUPERFAMILY SSF161098 36 222 5.89E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14080 c574da6f6339614647c5e68f6b27a447 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 60 229 6.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 Pfam PF13458 Periplasmic binding protein 28 371 1.6E-75 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 SUPERFAMILY SSF53822 28 383 6.73E-83 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 Gene3D G3DSA:3.40.50.2300 29 156 1.9E-16 T 28-03-2018 hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 Gene3D G3DSA:3.40.50.2300 157 309 2.3E-34 T 28-03-2018 hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 282 295 1.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 337 352 1.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 1.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19370 911b86998c66fa30a43c1814b406be7a 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.4E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS13590 6f0866c9e80743287a3607196c8885db 46 Pfam PF08031 Berberine and berberine like 14 43 5.2E-10 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 hmeg3_RS16665 50c0644c9e292eb3a65fa05ad9b47ba0 372 Pfam PF03594 Benzoate membrane transport protein 2 370 1.1E-145 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 hmeg3_RS16665 50c0644c9e292eb3a65fa05ad9b47ba0 372 TIGRFAM TIGR00843 benE: benzoate transporter 2 371 2.5E-140 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 hmeg3_RS11950 fbabc48485259b7b918bcc42b200663d 114 Gene3D G3DSA:3.30.70.120 1 112 5.4E-16 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal hmeg3_RS11950 fbabc48485259b7b918bcc42b200663d 114 SUPERFAMILY SSF54913 24 109 2.45E-13 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta hmeg3_RS11950 fbabc48485259b7b918bcc42b200663d 114 Pfam PF02641 Uncharacterized ACR, COG1993 28 100 2.7E-5 T 28-03-2018 IPR003793 Domain of unknown function DUF190 hmeg3_RS23285 c70d84bac44f982fbe8050697d38953b 427 Pfam PF07690 Major Facilitator Superfamily 27 365 2.9E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS23285 c70d84bac44f982fbe8050697d38953b 427 Gene3D G3DSA:1.20.1250.20 9 210 1.9E-22 T 28-03-2018 hmeg3_RS23285 c70d84bac44f982fbe8050697d38953b 427 SUPERFAMILY SSF103473 6 411 2.49E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS23285 c70d84bac44f982fbe8050697d38953b 427 Gene3D G3DSA:1.20.1250.20 222 415 2.0E-18 T 28-03-2018 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 Gene3D G3DSA:3.40.50.720 7 158 6.8E-27 T 28-03-2018 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 5.8E-144 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 SUPERFAMILY SSF56327 160 328 1.5E-57 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 PIRSF PIRSF000102 2 328 1.9E-64 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 56.266 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 SUPERFAMILY SSF51735 5 158 1.37E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 155 1.4E-36 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 Gene3D G3DSA:3.90.110.10 159 326 2.9E-47 T 28-03-2018 hmeg3_RS08740 d07beff93bd0c22f608dca51714b89cc 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 326 1.3E-31 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 hmeg3_RS15505 068f69a827eaeb19b772ffc79d57a71c 439 Pfam PF07394 Protein of unknown function (DUF1501) 65 422 4.2E-44 T 28-03-2018 IPR010869 Protein of unknown function DUF1501 hmeg3_RS12575 f60bf383f7c61a1bba90e7437b9ae015 246 Pfam PF04172 LrgB-like family 25 237 1.5E-74 T 28-03-2018 IPR007300 CidB/LrgB family hmeg3_RS07585 5019ce37bb0cbc7f82ecc91216716c38 547 SUPERFAMILY SSF56954 122 538 5.75E-56 T 28-03-2018 hmeg3_RS07585 5019ce37bb0cbc7f82ecc91216716c38 547 Pfam PF02321 Outer membrane efflux protein 353 514 1.1E-11 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS07585 5019ce37bb0cbc7f82ecc91216716c38 547 Pfam PF02321 Outer membrane efflux protein 136 329 3.5E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS07585 5019ce37bb0cbc7f82ecc91216716c38 547 Gene3D G3DSA:1.20.1600.10 128 540 1.3E-50 T 28-03-2018 hmeg3_RS23020 337e3d476a6b89a6fab900f188e8362b 80 Pfam PF04380 Membrane fusogenic activity 1 75 1.4E-31 T 28-03-2018 IPR007475 Membrane fusogenic activity hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 Pfam PF03466 LysR substrate binding domain 89 291 6.0E-36 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 SUPERFAMILY SSF46785 3 87 1.28E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 Gene3D G3DSA:3.40.190.10 178 263 2.9E-21 T 28-03-2018 hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 SUPERFAMILY SSF53850 89 293 5.61E-38 T 28-03-2018 hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 Gene3D G3DSA:3.40.190.10 92 177 4.6E-8 T 28-03-2018 hmeg3_RS01570 25e349f27d747292c4ac045981155576 298 Gene3D G3DSA:1.10.10.10 2 91 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03690 05fd7a3229331296ffa7dfbaf651185e 101 Gene3D G3DSA:3.40.50.1820 4 99 1.4E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS03690 05fd7a3229331296ffa7dfbaf651185e 101 SUPERFAMILY SSF53474 7 98 5.07E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS03690 05fd7a3229331296ffa7dfbaf651185e 101 Pfam PF12697 Alpha/beta hydrolase family 26 98 4.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS04085 c8742312db3ec26068a133d4519b11a2 398 Pfam PF07690 Major Facilitator Superfamily 15 346 2.4E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS04085 c8742312db3ec26068a133d4519b11a2 398 Gene3D G3DSA:1.20.1250.20 191 394 8.2E-17 T 28-03-2018 hmeg3_RS04085 c8742312db3ec26068a133d4519b11a2 398 Gene3D G3DSA:1.20.1250.20 6 190 4.8E-29 T 28-03-2018 hmeg3_RS04085 c8742312db3ec26068a133d4519b11a2 398 SUPERFAMILY SSF103473 10 388 3.79E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 PIRSF PIRSF001237 1 344 7.9E-139 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 SUPERFAMILY SSF51556 5 343 4.04E-147 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 Hamap MF_00219 Dihydroorotase [pyrC]. 3 344 43.745 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 ProSitePatterns PS00483 Dihydroorotase signature 2. 246 257 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 Gene3D G3DSA:3.20.20.140 11 344 6.9E-57 T 28-03-2018 hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 Pfam PF01979 Amidohydrolase family 12 311 5.8E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS04695 ec621d8b6308eb09e87ebfae89e6a911 344 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 5 343 1.3E-141 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 hmeg3_RS01595 e5798ab76406251661472c10e86c2470 359 Pfam PF03060 Nitronate monooxygenase 9 347 1.3E-77 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 hmeg3_RS01595 e5798ab76406251661472c10e86c2470 359 Gene3D G3DSA:3.20.20.70 2 358 5.0E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS01595 e5798ab76406251661472c10e86c2470 359 SUPERFAMILY SSF51412 5 73 3.21E-62 T 28-03-2018 hmeg3_RS01595 e5798ab76406251661472c10e86c2470 359 SUPERFAMILY SSF51412 103 342 3.21E-62 T 28-03-2018 hmeg3_RS03730 7a1e5ff79bcbc2cb93b3bdceed3e8f82 299 Pfam PF13673 Acetyltransferase (GNAT) domain 83 151 1.8E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS03730 7a1e5ff79bcbc2cb93b3bdceed3e8f82 299 Gene3D G3DSA:3.40.630.30 7 155 1.2E-14 T 28-03-2018 hmeg3_RS03730 7a1e5ff79bcbc2cb93b3bdceed3e8f82 299 SUPERFAMILY SSF55729 19 277 3.65E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS03730 7a1e5ff79bcbc2cb93b3bdceed3e8f82 299 Gene3D G3DSA:3.40.630.30 156 288 7.2E-5 T 28-03-2018 hmeg3_RS13110 d88d534fcc8eb0f136bdd3f94cc6b610 453 Pfam PF02417 Chromate transporter 25 186 7.2E-37 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 hmeg3_RS13110 d88d534fcc8eb0f136bdd3f94cc6b610 453 Pfam PF02417 Chromate transporter 262 446 2.9E-32 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 hmeg3_RS13110 d88d534fcc8eb0f136bdd3f94cc6b610 453 PIRSF PIRSF004810 7 453 5.3E-129 T 28-03-2018 IPR014047 Chromate transporter, long chain hmeg3_RS13110 d88d534fcc8eb0f136bdd3f94cc6b610 453 TIGRFAM TIGR00937 2A51: chromate efflux transporter 29 446 2.1E-69 T 28-03-2018 IPR014047 Chromate transporter, long chain hmeg3_RS08935 c257a793f20f006d3e964f3f7d1d5372 394 Gene3D G3DSA:1.20.1250.20 3 189 9.4E-29 T 28-03-2018 hmeg3_RS08935 c257a793f20f006d3e964f3f7d1d5372 394 Pfam PF07690 Major Facilitator Superfamily 8 314 2.7E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS08935 c257a793f20f006d3e964f3f7d1d5372 394 Gene3D G3DSA:1.20.1250.20 190 379 3.7E-18 T 28-03-2018 hmeg3_RS08935 c257a793f20f006d3e964f3f7d1d5372 394 SUPERFAMILY SSF103473 3 379 1.57E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS04995 f3cf7366fc967034eae723c07f8f1b30 335 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 315 8.9E-25 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS00495 13989cbabd8e6af007e66b965b93ecde 192 Pfam PF14235 Domain of unknown function (DUF4337) 32 188 2.9E-35 T 28-03-2018 IPR025570 Protein of unknown function DUF4337 hmeg3_RS09410 f91f479a514ae76e546fc632f8e21743 427 Gene3D G3DSA:2.30.40.10 1 66 5.0E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS09410 f91f479a514ae76e546fc632f8e21743 427 SUPERFAMILY SSF51338 361 403 1.94E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS09410 f91f479a514ae76e546fc632f8e21743 427 SUPERFAMILY SSF51338 1 51 1.94E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 hmeg3_RS09410 f91f479a514ae76e546fc632f8e21743 427 Pfam PF07969 Amidohydrolase family 39 399 1.0E-49 T 28-03-2018 IPR013108 Amidohydrolase 3 hmeg3_RS09410 f91f479a514ae76e546fc632f8e21743 427 Gene3D G3DSA:3.20.20.140 67 359 1.2E-43 T 28-03-2018 hmeg3_RS09410 f91f479a514ae76e546fc632f8e21743 427 SUPERFAMILY SSF51556 51 370 1.32E-105 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS12075 14573632cb67e9328540ddb39a8f8124 159 SUPERFAMILY SSF54593 4 157 4.78E-50 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS12075 14573632cb67e9328540ddb39a8f8124 159 Gene3D G3DSA:3.10.180.10 1 133 4.4E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS12075 14573632cb67e9328540ddb39a8f8124 159 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 118 4.1E-47 T 28-03-2018 IPR028973 PhnB-like hmeg3_RS12075 14573632cb67e9328540ddb39a8f8124 159 PIRSF PIRSF021700 1 159 6.6E-67 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase hmeg3_RS20625 59bfbd773a92e664787b2c7dd6c0d403 151 Gene3D G3DSA:3.10.129.10 2 143 9.0E-25 T 28-03-2018 hmeg3_RS20625 59bfbd773a92e664787b2c7dd6c0d403 151 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 126 1.5E-13 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 hmeg3_RS20625 59bfbd773a92e664787b2c7dd6c0d403 151 SUPERFAMILY SSF54637 6 148 3.88E-26 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS20625 59bfbd773a92e664787b2c7dd6c0d403 151 Pfam PF03061 Thioesterase superfamily 56 126 1.3E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS10440 e2d59e80c7350962754b87cd196494fd 447 Gene3D G3DSA:3.90.1300.10 2 443 8.2E-124 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS10440 e2d59e80c7350962754b87cd196494fd 447 SUPERFAMILY SSF75304 3 443 1.96E-119 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS10440 e2d59e80c7350962754b87cd196494fd 447 Pfam PF01425 Amidase 21 432 1.3E-91 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS17720 e8fa0c979f851c33d1d39d4e2efa7252 854 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 98 773 48.545 T 28-03-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 hmeg3_RS17720 e8fa0c979f851c33d1d39d4e2efa7252 854 SUPERFAMILY SSF53448 272 561 1.91E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS17720 e8fa0c979f851c33d1d39d4e2efa7252 854 Pfam PF00535 Glycosyl transferase family 2 274 456 1.3E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS17720 e8fa0c979f851c33d1d39d4e2efa7252 854 Gene3D G3DSA:3.90.550.10 255 531 9.7E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS16185 a8134542fa52ce7c023d07cdfccecb60 86 Pfam PF00550 Phosphopantetheine attachment site 6 61 2.4E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS16185 a8134542fa52ce7c023d07cdfccecb60 86 SUPERFAMILY SSF47336 4 83 2.88E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain hmeg3_RS16185 a8134542fa52ce7c023d07cdfccecb60 86 ProSitePatterns PS00012 Phosphopantetheine attachment site. 36 51 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site hmeg3_RS16185 a8134542fa52ce7c023d07cdfccecb60 86 Gene3D G3DSA:1.10.1200.10 3 86 1.4E-16 T 28-03-2018 hmeg3_RS04215 5f58223b8805047df7684e14f32d2d56 311 SUPERFAMILY SSF53850 52 307 9.15E-44 T 28-03-2018 hmeg3_RS04215 5f58223b8805047df7684e14f32d2d56 311 Gene3D G3DSA:3.40.190.10 48 150 3.7E-5 T 28-03-2018 hmeg3_RS04215 5f58223b8805047df7684e14f32d2d56 311 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 56 304 6.0E-61 T 28-03-2018 hmeg3_RS04215 5f58223b8805047df7684e14f32d2d56 311 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 24 278 9.0E-64 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 hmeg3_RS04215 5f58223b8805047df7684e14f32d2d56 311 Gene3D G3DSA:3.40.190.10 151 254 7.1E-27 T 28-03-2018 hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 Gene3D G3DSA:1.10.10.10 125 232 5.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 SMART SM00862 151 227 1.4E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 Pfam PF00072 Response regulator receiver domain 8 117 3.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 SUPERFAMILY SSF52172 7 168 2.85E-36 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 SMART SM00448 6 116 1.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 SUPERFAMILY SSF46894 132 227 4.25E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 Gene3D G3DSA:3.40.50.2300 3 124 5.8E-33 T 28-03-2018 hmeg3_RS06065 1aeebdc90266acd5364d33954ce8d656 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 2.1E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 SUPERFAMILY SSF110921 395 502 3.66E-25 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 Pfam PF00682 HMGL-like 6 275 2.5E-95 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 Gene3D G3DSA:3.20.20.70 1 333 2.4E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 500 1.6E-207 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 SMART SM00917 372 503 1.2E-39 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 200 213 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 3 512 42.006 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 SUPERFAMILY SSF51569 4 293 2.56E-95 T 28-03-2018 hmeg3_RS13930 e4dec6588e0f12fa21b26d2116177fa7 514 Pfam PF08502 LeuA allosteric (dimerisation) domain 372 502 5.4E-32 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 hmeg3_RS10210 5afd61346867d29af6516df649f93637 350 SUPERFAMILY SSF52172 6 128 2.28E-15 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10210 5afd61346867d29af6516df649f93637 350 Pfam PF00072 Response regulator receiver domain 9 117 8.2E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10210 5afd61346867d29af6516df649f93637 350 Gene3D G3DSA:3.30.565.10 223 350 3.3E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10210 5afd61346867d29af6516df649f93637 350 SMART SM00448 7 121 8.9E-4 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10210 5afd61346867d29af6516df649f93637 350 Gene3D G3DSA:3.40.50.2300 2 214 3.9E-14 T 28-03-2018 hmeg3_RS07985 f44d9869a7f71e5875f8ecf4db5efb4d 159 Gene3D G3DSA:3.10.180.10 2 133 4.9E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS07985 f44d9869a7f71e5875f8ecf4db5efb4d 159 SUPERFAMILY SSF54593 3 125 6.19E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS07985 f44d9869a7f71e5875f8ecf4db5efb4d 159 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 hmeg3_RS07985 f44d9869a7f71e5875f8ecf4db5efb4d 159 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 119 5.2E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS08895 3885876a308b54584dcceef9c59c893c 79 SUPERFAMILY SSF50182 8 70 4.58E-24 T 28-03-2018 IPR010920 LSM domain hmeg3_RS08895 3885876a308b54584dcceef9c59c893c 79 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 27.689 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 hmeg3_RS08895 3885876a308b54584dcceef9c59c893c 79 Gene3D G3DSA:2.30.30.100 5 74 9.8E-33 T 28-03-2018 hmeg3_RS08895 3885876a308b54584dcceef9c59c893c 79 Pfam PF17209 Hfq protein 8 69 2.8E-31 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 hmeg3_RS08895 3885876a308b54584dcceef9c59c893c 79 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 65 1.4E-28 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 hmeg3_RS09730 23d83236e5335d433f3fce6a11b1c8cd 86 Pfam PF01381 Helix-turn-helix 24 77 8.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS09730 23d83236e5335d433f3fce6a11b1c8cd 86 Gene3D G3DSA:1.10.260.40 18 83 6.0E-16 T 28-03-2018 hmeg3_RS09730 23d83236e5335d433f3fce6a11b1c8cd 86 SMART SM00530 22 77 9.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS09730 23d83236e5335d433f3fce6a11b1c8cd 86 SUPERFAMILY SSF47413 18 83 2.11E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS03195 a27ee9cd32edbae27d35b5e59b7a7dff 207 Pfam PF05137 Fimbrial assembly protein (PilN) 101 182 4.7E-12 T 28-03-2018 IPR007813 Fimbrial assembly PilN hmeg3_RS12070 2e088a5c11257dba797b03a784bf91a5 134 Gene3D G3DSA:3.30.530.20 1 134 3.7E-26 T 28-03-2018 IPR023393 START-like domain hmeg3_RS12070 2e088a5c11257dba797b03a784bf91a5 134 SUPERFAMILY SSF55961 2 133 1.29E-30 T 28-03-2018 hmeg3_RS12070 2e088a5c11257dba797b03a784bf91a5 134 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 132 3.7E-22 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 hmeg3_RS05170 44e3660ec788f3fedb77482fa24d7f99 305 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 2.9E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05170 44e3660ec788f3fedb77482fa24d7f99 305 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site hmeg3_RS05170 44e3660ec788f3fedb77482fa24d7f99 305 Pfam PF16074 Type IV Pilus-assembly protein W 172 302 5.2E-31 T 28-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 hmeg3_RS15605 a3f8c965ee8714ab5f9dbbc72f3285de 139 SMART SM00754 25 138 2.2E-32 T 28-03-2018 IPR010895 CHRD hmeg3_RS15605 a3f8c965ee8714ab5f9dbbc72f3285de 139 Pfam PF07452 CHRD domain 28 136 2.0E-29 T 28-03-2018 IPR010895 CHRD hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 Gene3D G3DSA:3.40.50.2300 2 142 3.3E-40 T 28-03-2018 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 SMART SM00448 3 116 4.2E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 SUPERFAMILY SSF52172 3 131 1.27E-35 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 SMART SM00421 149 206 3.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 Gene3D G3DSA:1.10.10.10 143 216 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 Pfam PF00072 Response regulator receiver domain 5 116 3.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 4.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 4.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 4.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 SUPERFAMILY SSF46894 143 212 2.04E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS10525 9ad36cf5b834709344c896952c1e3f83 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 4.9E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 hmeg3_RS20805 5d0bcb1399d68ca3547f7e4a29921204 138 Gene3D G3DSA:3.10.490.10 2 135 1.8E-6 T 28-03-2018 hmeg3_RS20805 5d0bcb1399d68ca3547f7e4a29921204 138 SUPERFAMILY SSF110857 10 105 4.32E-5 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 30 466 3.6E-177 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 175 386 5.8E-76 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 35 97 2.9E-4 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 33 464 2.8E-199 T 28-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 377 386 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 SUPERFAMILY SSF52540 122 391 8.05E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 SMART SM00382 187 370 3.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS08305 55e47b2bb426b2f41a3eae663c94f4e1 467 Gene3D G3DSA:3.40.50.300 106 386 9.7E-85 T 28-03-2018 hmeg3_RS16535 1c8ec380c1e781ed61cd422435f03d5d 593 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 129 139 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS16535 1c8ec380c1e781ed61cd422435f03d5d 593 SUPERFAMILY SSF143975 5 379 7.59E-110 T 28-03-2018 hmeg3_RS16535 1c8ec380c1e781ed61cd422435f03d5d 593 SUPERFAMILY SSF52016 383 579 3.45E-47 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS16535 1c8ec380c1e781ed61cd422435f03d5d 593 Pfam PF00920 Dehydratase family 46 573 5.0E-150 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS21410 f3524c257b15edc2c0c8c15d6e8abbde 294 SUPERFAMILY SSF52540 29 241 3.33E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21410 f3524c257b15edc2c0c8c15d6e8abbde 294 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS21410 f3524c257b15edc2c0c8c15d6e8abbde 294 Pfam PF00005 ABC transporter 45 187 8.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS21410 f3524c257b15edc2c0c8c15d6e8abbde 294 Gene3D G3DSA:3.40.50.300 24 248 1.0E-59 T 28-03-2018 hmeg3_RS21410 f3524c257b15edc2c0c8c15d6e8abbde 294 SMART SM00382 54 238 3.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 SMART SM00930 270 345 4.9E-28 T 28-03-2018 IPR018449 NIL domain hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 Pfam PF09383 NIL domain 273 344 1.1E-22 T 28-03-2018 IPR018449 NIL domain hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 SUPERFAMILY SSF55021 261 348 6.52E-23 T 28-03-2018 hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 SUPERFAMILY SSF52540 1 240 1.73E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 Gene3D G3DSA:3.40.50.300 1 258 6.2E-79 T 28-03-2018 hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 Gene3D G3DSA:3.30.70.260 259 349 2.3E-27 T 28-03-2018 hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 Pfam PF00005 ABC transporter 22 169 1.8E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS05815 996d52a329dff67e3511df8c8390948e 349 SMART SM00382 30 226 8.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19105 aae7c6c02396ca02e918a6af68fc8aa6 417 Pfam PF01547 Bacterial extracellular solute-binding protein 52 294 2.3E-23 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 hmeg3_RS19105 aae7c6c02396ca02e918a6af68fc8aa6 417 SUPERFAMILY SSF53850 27 416 1.36E-59 T 28-03-2018 hmeg3_RS19105 aae7c6c02396ca02e918a6af68fc8aa6 417 Gene3D G3DSA:3.40.190.10 234 375 9.8E-11 T 28-03-2018 hmeg3_RS19105 aae7c6c02396ca02e918a6af68fc8aa6 417 Gene3D G3DSA:3.40.190.10 26 233 6.8E-25 T 28-03-2018 hmeg3_RS07810 2a29660a083ba5bd1ab332b1e7ca0ae1 469 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 28 469 1.4E-132 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase hmeg3_RS07810 2a29660a083ba5bd1ab332b1e7ca0ae1 469 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 36 469 1.2E-146 T 28-03-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 hmeg3_RS07810 2a29660a083ba5bd1ab332b1e7ca0ae1 469 Pfam PF13727 CoA-binding domain 77 240 2.1E-18 T 28-03-2018 hmeg3_RS07810 2a29660a083ba5bd1ab332b1e7ca0ae1 469 Gene3D G3DSA:3.40.50.720 140 262 2.9E-8 T 28-03-2018 hmeg3_RS07810 2a29660a083ba5bd1ab332b1e7ca0ae1 469 Pfam PF02397 Bacterial sugar transferase 276 463 6.0E-64 T 28-03-2018 IPR003362 Bacterial sugar transferase hmeg3_RS15330 4cc12c69e641ab649bc4b318ec6247dc 123 Pfam PF01903 CbiX 10 114 5.5E-25 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 hmeg3_RS15330 4cc12c69e641ab649bc4b318ec6247dc 123 Gene3D G3DSA:3.40.50.1400 1 119 1.6E-26 T 28-03-2018 hmeg3_RS15330 4cc12c69e641ab649bc4b318ec6247dc 123 SUPERFAMILY SSF53800 1 117 1.19E-30 T 28-03-2018 hmeg3_RS24065 702b86559c6f7a715348ce33e8f4c72a 250 Pfam PF06912 Protein of unknown function (DUF1275) 22 234 4.6E-36 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 hmeg3_RS12775 9e99c44517ac8934e990352468aa64d7 441 Pfam PF07804 HipA-like C-terminal domain 156 399 1.9E-46 T 28-03-2018 IPR012893 HipA-like, C-terminal hmeg3_RS12775 9e99c44517ac8934e990352468aa64d7 441 Pfam PF13657 HipA N-terminal domain 7 121 2.8E-20 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 hmeg3_RS12775 9e99c44517ac8934e990352468aa64d7 441 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 10 120 4.7E-9 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 hmeg3_RS06860 400a2761afdb1376419154bf431557c6 104 Pfam PF06865 Protein of unknown function (DUF1255) 13 103 1.6E-39 T 28-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase hmeg3_RS06860 400a2761afdb1376419154bf431557c6 104 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 11 104 28.638 T 28-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase hmeg3_RS06860 400a2761afdb1376419154bf431557c6 104 Gene3D G3DSA:2.60.120.10 3 103 9.6E-45 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS06860 400a2761afdb1376419154bf431557c6 104 SUPERFAMILY SSF51182 12 103 2.12E-36 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS20715 501fd19465780ced6f3b7df4d0cde2c3 340 Gene3D G3DSA:2.60.40.1180 27 161 2.4E-10 T 28-03-2018 hmeg3_RS20715 501fd19465780ced6f3b7df4d0cde2c3 340 SUPERFAMILY SSF81901 26 137 1.7E-13 T 28-03-2018 hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 8.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 8.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 8.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 SMART SM00387 316 422 5.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 SUPERFAMILY SSF55874 280 420 1.57E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 Gene3D G3DSA:3.30.565.10 277 433 7.6E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS10345 7e286e0e3e24cc7d845950461c35dfa0 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 421 1.2E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain hmeg3_RS12390 9f73604e5ad143e8e5b955a47b1629a3 200 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 29 200 9.8E-58 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 hmeg3_RS12390 9f73604e5ad143e8e5b955a47b1629a3 200 Gene3D G3DSA:3.40.50.300 8 200 5.7E-67 T 28-03-2018 hmeg3_RS12390 9f73604e5ad143e8e5b955a47b1629a3 200 SUPERFAMILY SSF52540 10 200 1.82E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12390 9f73604e5ad143e8e5b955a47b1629a3 200 PIRSF PIRSF015617 3 200 8.5E-69 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 hmeg3_RS12390 9f73604e5ad143e8e5b955a47b1629a3 200 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 26 200 5.5E-65 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 hmeg3_RS07990 79d6a60a42e9cd0afbfa3195b6666991 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 42 312 7.1E-21 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS07990 79d6a60a42e9cd0afbfa3195b6666991 314 SUPERFAMILY SSF51735 102 282 5.21E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS07990 79d6a60a42e9cd0afbfa3195b6666991 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 281 5.3E-52 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS07990 79d6a60a42e9cd0afbfa3195b6666991 314 SUPERFAMILY SSF52283 8 135 8.51E-27 T 28-03-2018 hmeg3_RS07990 79d6a60a42e9cd0afbfa3195b6666991 314 Gene3D G3DSA:3.40.50.720 5 115 2.8E-26 T 28-03-2018 hmeg3_RS07990 79d6a60a42e9cd0afbfa3195b6666991 314 Gene3D G3DSA:3.40.50.720 116 284 1.9E-53 T 28-03-2018 hmeg3_RS05000 062b1e3e9da6ea27c89a3a0c81afb05f 212 Pfam PF13417 Glutathione S-transferase, N-terminal domain 16 85 1.0E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS05000 062b1e3e9da6ea27c89a3a0c81afb05f 212 SUPERFAMILY SSF52833 13 111 4.31E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS05000 062b1e3e9da6ea27c89a3a0c81afb05f 212 Pfam PF14834 Glutathione S-transferase, C-terminal domain 95 206 5.7E-45 T 28-03-2018 IPR034338 Glutathione S-transferases, subfamily 4, C-terminal KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 hmeg3_RS05000 062b1e3e9da6ea27c89a3a0c81afb05f 212 Gene3D G3DSA:1.20.1050.10 102 205 7.2E-14 T 28-03-2018 hmeg3_RS05000 062b1e3e9da6ea27c89a3a0c81afb05f 212 Gene3D G3DSA:3.40.30.10 2 101 5.0E-21 T 28-03-2018 hmeg3_RS05000 062b1e3e9da6ea27c89a3a0c81afb05f 212 SUPERFAMILY SSF47616 89 206 3.19E-12 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS10655 9aa82437357146cf58c4e8b79267dbad 206 Pfam PF04279 Intracellular septation protein A 1 204 3.3E-67 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 hmeg3_RS10655 9aa82437357146cf58c4e8b79267dbad 206 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 204 1.4E-52 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 hmeg3_RS10655 9aa82437357146cf58c4e8b79267dbad 206 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 205 18.809 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 Gene3D G3DSA:3.40.50.720 2 281 3.2E-63 T 28-03-2018 hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 Pfam PF00106 short chain dehydrogenase 5 191 2.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 SUPERFAMILY SSF51735 4 249 1.69E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS01505 90c3e2bcd7ea87bf5cbd4987f92d433e 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS17170 18c308978a05703229607298919bb117 341 Gene3D G3DSA:3.40.1090.10 1 235 2.3E-38 T 28-03-2018 hmeg3_RS17170 18c308978a05703229607298919bb117 341 SUPERFAMILY SSF52151 113 330 9.16E-48 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS17170 18c308978a05703229607298919bb117 341 SUPERFAMILY SSF52151 1 83 9.16E-48 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS17170 18c308978a05703229607298919bb117 341 Pfam PF01734 Patatin-like phospholipase 8 205 2.9E-22 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 hmeg3_RS21095 1c1fe3f0b938ea9a8ef553e7ab5a8efd 386 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 286 2.4E-27 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain hmeg3_RS21095 1c1fe3f0b938ea9a8ef553e7ab5a8efd 386 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 51 369 3.9E-73 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 hmeg3_RS21095 1c1fe3f0b938ea9a8ef553e7ab5a8efd 386 Gene3D G3DSA:1.20.1600.10 54 314 4.0E-34 T 28-03-2018 hmeg3_RS21095 1c1fe3f0b938ea9a8ef553e7ab5a8efd 386 SUPERFAMILY SSF111369 64 290 3.79E-31 T 28-03-2018 hmeg3_RS06690 12f1a3bcb23f7094117adcce3913182d 225 Pfam PF07812 TfuA-like protein 54 172 2.3E-29 T 28-03-2018 IPR012924 TfuA-like, core hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 Pfam PF00482 Type II secretion system (T2SS), protein F 278 400 9.2E-29 T 28-03-2018 IPR018076 Type II secretion system F domain hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 Pfam PF00482 Type II secretion system (T2SS), protein F 74 197 3.5E-32 T 28-03-2018 IPR018076 Type II secretion system F domain hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 389 408 1.1E-17 T 28-03-2018 IPR003004 GspF/PilC family hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 70 82 1.1E-17 T 28-03-2018 IPR003004 GspF/PilC family hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 169 197 1.1E-17 T 28-03-2018 IPR003004 GspF/PilC family hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 373 387 1.1E-17 T 28-03-2018 IPR003004 GspF/PilC family hmeg3_RS21910 501bf90a981c085b917de514b888aa37 408 Gene3D G3DSA:1.10.357.10 43 196 6.6E-4 T 28-03-2018 hmeg3_RS16930 384b2697092e924ff4c8687689352d1d 275 Gene3D G3DSA:1.10.3210.10 1 240 8.8E-39 T 28-03-2018 hmeg3_RS16930 384b2697092e924ff4c8687689352d1d 275 SUPERFAMILY SSF109604 3 262 4.44E-65 T 28-03-2018 hmeg3_RS16930 384b2697092e924ff4c8687689352d1d 275 Pfam PF08668 HDOD domain 13 201 2.1E-56 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS14930 4febe11970429d16395b94f13cdd184d 344 Pfam PF01435 Peptidase family M48 166 341 9.1E-26 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 hmeg3_RS14930 4febe11970429d16395b94f13cdd184d 344 Gene3D G3DSA:3.30.2010.10 158 251 1.7E-17 T 28-03-2018 hmeg3_RS11010 ba862ffb0f2a954e8772ec9b9ffff53f 336 Pfam PF01380 SIS domain 38 159 6.0E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS11010 ba862ffb0f2a954e8772ec9b9ffff53f 336 Pfam PF01380 SIS domain 194 278 4.3E-14 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 hmeg3_RS11010 ba862ffb0f2a954e8772ec9b9ffff53f 336 Gene3D G3DSA:3.40.50.10490 2 167 1.5E-28 T 28-03-2018 hmeg3_RS11010 ba862ffb0f2a954e8772ec9b9ffff53f 336 Gene3D G3DSA:3.40.50.10490 189 336 6.0E-33 T 28-03-2018 hmeg3_RS11010 ba862ffb0f2a954e8772ec9b9ffff53f 336 SUPERFAMILY SSF53697 14 334 2.35E-69 T 28-03-2018 hmeg3_RS10390 7e6bb948c77d7ad66e3729a9c430356a 277 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS10390 7e6bb948c77d7ad66e3729a9c430356a 277 Pfam PF00494 Squalene/phytoene synthase 13 263 2.3E-79 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 hmeg3_RS10390 7e6bb948c77d7ad66e3729a9c430356a 277 SUPERFAMILY SSF48576 3 276 1.58E-89 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS10390 7e6bb948c77d7ad66e3729a9c430356a 277 Gene3D G3DSA:1.10.600.10 2 277 7.0E-86 T 28-03-2018 IPR008949 Isoprenoid synthase domain hmeg3_RS10390 7e6bb948c77d7ad66e3729a9c430356a 277 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 122 137 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 hmeg3_RS10390 7e6bb948c77d7ad66e3729a9c430356a 277 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 4.9E-118 T 28-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 hmeg3_RS04545 b7498cd519d58cd3b2852eb3ab591871 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 1.7E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS04545 b7498cd519d58cd3b2852eb3ab591871 216 SUPERFAMILY SSF161098 11 197 1.57E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04545 b7498cd519d58cd3b2852eb3ab591871 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 212 6.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04545 b7498cd519d58cd3b2852eb3ab591871 216 Gene3D G3DSA:1.10.3720.10 2 216 7.4E-41 T 28-03-2018 hmeg3_RS03455 4dedae762a4c10d5c2ccc02f6d5f799f 303 SMART SM00382 28 208 4.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS03455 4dedae762a4c10d5c2ccc02f6d5f799f 303 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS03455 4dedae762a4c10d5c2ccc02f6d5f799f 303 Pfam PF00005 ABC transporter 20 161 4.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS03455 4dedae762a4c10d5c2ccc02f6d5f799f 303 Gene3D G3DSA:3.40.50.300 1 240 1.5E-64 T 28-03-2018 hmeg3_RS03455 4dedae762a4c10d5c2ccc02f6d5f799f 303 SUPERFAMILY SSF52540 3 223 1.67E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10610 436ee1ba8b63cb6f84726f725fa9f3fc 422 Gene3D G3DSA:3.50.50.60 2 421 6.0E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10610 436ee1ba8b63cb6f84726f725fa9f3fc 422 Pfam PF01266 FAD dependent oxidoreductase 4 401 2.8E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS10610 436ee1ba8b63cb6f84726f725fa9f3fc 422 SUPERFAMILY SSF51905 3 55 2.72E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10610 436ee1ba8b63cb6f84726f725fa9f3fc 422 SUPERFAMILY SSF51905 107 274 2.72E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10610 436ee1ba8b63cb6f84726f725fa9f3fc 422 SUPERFAMILY SSF51905 364 412 2.72E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 Gene3D G3DSA:1.10.357.10 59 190 1.6E-20 T 28-03-2018 hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 SUPERFAMILY SSF48498 81 189 1.66E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 SUPERFAMILY SSF46689 6 75 9.98E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS10100 7b00d5551208f7b71718c2e83dcd2de3 195 Gene3D G3DSA:1.10.10.60 3 58 1.3E-15 T 28-03-2018 hmeg3_RS03675 eb61366b655fc1666559f22663da514b 393 SUPERFAMILY SSF53756 5 385 1.13E-66 T 28-03-2018 hmeg3_RS03675 eb61366b655fc1666559f22663da514b 393 Gene3D G3DSA:3.40.50.2000 1 184 1.5E-13 T 28-03-2018 hmeg3_RS03675 eb61366b655fc1666559f22663da514b 393 Pfam PF13439 Glycosyltransferase Family 4 14 178 2.1E-16 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 hmeg3_RS03675 eb61366b655fc1666559f22663da514b 393 Gene3D G3DSA:3.40.50.2000 185 365 3.1E-42 T 28-03-2018 hmeg3_RS03675 eb61366b655fc1666559f22663da514b 393 TIGRFAM TIGR04047 MSMEG_0565_glyc: glycosyltransferase, MSMEG_0565 family 3 382 8.2E-154 T 28-03-2018 IPR023986 Glycosyltransferase, putative, MSMEG0565 family hmeg3_RS03675 eb61366b655fc1666559f22663da514b 393 Pfam PF00534 Glycosyl transferases group 1 196 346 2.3E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 hmeg3_RS20215 848d08f829554b666fecf7fbce507488 105 Pfam PF13937 Domain of unknown function (DUF4212) 24 96 4.1E-25 T 28-03-2018 IPR019886 Sodium symporter small subunit, predicted hmeg3_RS20215 848d08f829554b666fecf7fbce507488 105 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 24 97 1.0E-25 T 28-03-2018 IPR019886 Sodium symporter small subunit, predicted hmeg3_RS18365 9c25a239e57876761cb14aeb8d7de794 398 Gene3D G3DSA:3.40.1090.10 2 330 9.1E-37 T 28-03-2018 hmeg3_RS18365 9c25a239e57876761cb14aeb8d7de794 398 SUPERFAMILY SSF52151 5 255 7.59E-40 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS18365 9c25a239e57876761cb14aeb8d7de794 398 Pfam PF01734 Patatin-like phospholipase 10 234 5.8E-20 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 hmeg3_RS23980 4e1853241128ba729b7bc3b65838b406 334 Pfam PF04773 FecR protein 119 214 2.0E-21 T 28-03-2018 IPR006860 FecR protein hmeg3_RS23980 4e1853241128ba729b7bc3b65838b406 334 Pfam PF16220 Domain of unknown function (DUF4880) 19 60 1.3E-13 T 28-03-2018 IPR032623 FecR, N-terminal hmeg3_RS23980 4e1853241128ba729b7bc3b65838b406 334 PIRSF PIRSF018266 8 331 8.1E-88 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component hmeg3_RS23980 4e1853241128ba729b7bc3b65838b406 334 Gene3D G3DSA:1.10.620.20 4 105 6.2E-4 T 28-03-2018 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 SUPERFAMILY SSF50249 1 65 4.29E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 Gene3D G3DSA:2.40.50.140 1 66 3.4E-31 T 28-03-2018 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 PIRSF PIRSF002599 1 67 3.1E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 SMART SM00357 3 67 7.9E-34 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 9.1E-33 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 PRINTS PR00050 Cold shock protein signature 25 34 4.3E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 PRINTS PR00050 Cold shock protein signature 40 58 4.3E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS06630 170a23c2ae3992578984059a7b52cd7f 67 PRINTS PR00050 Cold shock protein signature 4 19 4.3E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 hmeg3_RS04335 edacb4fe0ab856fe3b3cf8973bc7cfb3 291 Gene3D G3DSA:3.40.50.300 5 167 3.7E-8 T 28-03-2018 hmeg3_RS04335 edacb4fe0ab856fe3b3cf8973bc7cfb3 291 Pfam PF03668 P-loop ATPase protein family 5 290 8.5E-90 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 hmeg3_RS04335 edacb4fe0ab856fe3b3cf8973bc7cfb3 291 PIRSF PIRSF005052 5 291 1.2E-103 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 hmeg3_RS04335 edacb4fe0ab856fe3b3cf8973bc7cfb3 291 SUPERFAMILY SSF52540 5 165 3.29E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04335 edacb4fe0ab856fe3b3cf8973bc7cfb3 291 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 5 291 37.988 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 hmeg3_RS21720 9b346d70e6d612e7f33c0bfd5a598784 691 SMART SM00955 235 522 1.3E-70 T 28-03-2018 hmeg3_RS21720 9b346d70e6d612e7f33c0bfd5a598784 691 Pfam PF00773 RNB domain 483 521 2.8E-9 T 28-03-2018 hmeg3_RS21720 9b346d70e6d612e7f33c0bfd5a598784 691 Pfam PF00773 RNB domain 239 467 7.1E-38 T 28-03-2018 hmeg3_RS21720 9b346d70e6d612e7f33c0bfd5a598784 691 SUPERFAMILY SSF50249 210 571 2.34E-77 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS16455 17815277bb9990d3b3eebf488c6815ad 150 Gene3D G3DSA:2.60.40.790 6 138 2.1E-20 T 28-03-2018 IPR008978 HSP20-like chaperone hmeg3_RS16455 17815277bb9990d3b3eebf488c6815ad 150 SUPERFAMILY SSF49764 6 138 5.93E-20 T 28-03-2018 IPR008978 HSP20-like chaperone hmeg3_RS16455 17815277bb9990d3b3eebf488c6815ad 150 Pfam PF00011 Hsp20/alpha crystallin family 44 138 3.4E-17 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain hmeg3_RS07875 4072c02e215d1f383cb44a8ab0a4815a 383 PIRSF PIRSF006078 8 380 1.7E-106 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 hmeg3_RS07875 4072c02e215d1f383cb44a8ab0a4815a 383 Gene3D G3DSA:3.90.1510.10 48 279 1.0E-74 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 hmeg3_RS07875 4072c02e215d1f383cb44a8ab0a4815a 383 Pfam PF02595 Glycerate kinase family 9 376 6.1E-121 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 hmeg3_RS07875 4072c02e215d1f383cb44a8ab0a4815a 383 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 9 376 6.0E-108 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 hmeg3_RS07875 4072c02e215d1f383cb44a8ab0a4815a 383 SUPERFAMILY SSF110738 9 377 6.28E-108 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 hmeg3_RS01820 dcf29ee4f9bd867795a22807e51038d1 227 Gene3D G3DSA:1.10.3720.10 3 227 4.0E-35 T 28-03-2018 hmeg3_RS01820 dcf29ee4f9bd867795a22807e51038d1 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 223 2.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS01820 dcf29ee4f9bd867795a22807e51038d1 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 118 3.6E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS01820 dcf29ee4f9bd867795a22807e51038d1 227 SUPERFAMILY SSF161098 14 209 6.54E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS20785 59710bb3eab50d50d8231ef34ea9c279 317 PIRSF PIRSF016020 24 317 1.4E-52 T 28-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 hmeg3_RS20785 59710bb3eab50d50d8231ef34ea9c279 317 Pfam PF01263 Aldose 1-epimerase 45 313 1.6E-37 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 hmeg3_RS20785 59710bb3eab50d50d8231ef34ea9c279 317 Gene3D G3DSA:2.70.98.10 12 317 9.7E-57 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 hmeg3_RS20785 59710bb3eab50d50d8231ef34ea9c279 317 SUPERFAMILY SSF74650 44 313 1.38E-49 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 hmeg3_RS07025 f5477ee9172793d5e004b557f0ae705e 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 310 1.2E-47 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS07025 f5477ee9172793d5e004b557f0ae705e 324 Gene3D G3DSA:1.10.3470.10 22 318 4.3E-26 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS00510 b953925a0d86581c9d142a60beac3687 203 Gene3D G3DSA:1.20.1050.10 93 201 3.2E-21 T 28-03-2018 hmeg3_RS00510 b953925a0d86581c9d142a60beac3687 203 Gene3D G3DSA:3.40.30.10 1 92 3.1E-33 T 28-03-2018 hmeg3_RS00510 b953925a0d86581c9d142a60beac3687 203 SUPERFAMILY SSF47616 79 196 1.34E-25 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS00510 b953925a0d86581c9d142a60beac3687 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 73 1.3E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS00510 b953925a0d86581c9d142a60beac3687 203 SUPERFAMILY SSF52833 1 84 5.4E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS00510 b953925a0d86581c9d142a60beac3687 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 122 189 3.0E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS08265 fc83f5be7d5e8b00ed37ff84030618e2 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 6.1E-32 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS08265 fc83f5be7d5e8b00ed37ff84030618e2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.1E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS08265 fc83f5be7d5e8b00ed37ff84030618e2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.1E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS08265 fc83f5be7d5e8b00ed37ff84030618e2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.1E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS08265 fc83f5be7d5e8b00ed37ff84030618e2 89 PIRSF PIRSF004669 1 89 9.0E-34 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 hmeg3_RS08265 fc83f5be7d5e8b00ed37ff84030618e2 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 7.8E-34 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 hmeg3_RS14560 7e4f8d61331437dbdd0a88cdda14ef31 118 SUPERFAMILY SSF54534 3 118 5.3E-44 T 28-03-2018 hmeg3_RS14560 7e4f8d61331437dbdd0a88cdda14ef31 118 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 21 116 6.2E-35 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain hmeg3_RS14560 7e4f8d61331437dbdd0a88cdda14ef31 118 Gene3D G3DSA:3.10.50.40 1 118 5.1E-47 T 28-03-2018 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 Gene3D G3DSA:1.10.10.10 1 82 7.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 SUPERFAMILY SSF53850 87 287 2.17E-30 T 28-03-2018 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 SUPERFAMILY SSF46785 3 78 1.29E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 Gene3D G3DSA:3.40.190.10 87 180 1.3E-14 T 28-03-2018 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 6.9E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 Pfam PF03466 LysR substrate binding domain 86 286 3.6E-29 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 Gene3D G3DSA:3.40.190.10 181 258 7.8E-13 T 28-03-2018 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS16375 07fe136304bf389554d1f76a1312c60c 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS06970 1f151b5fbbec955457c0d287c867c5d1 540 Gene3D G3DSA:1.20.120.330 404 537 4.5E-6 T 28-03-2018 hmeg3_RS06970 1f151b5fbbec955457c0d287c867c5d1 540 Pfam PF02470 MlaD protein 165 224 3.9E-7 T 28-03-2018 IPR003399 Mce/MlaD hmeg3_RS06970 1f151b5fbbec955457c0d287c867c5d1 540 Pfam PF02470 MlaD protein 293 396 6.8E-16 T 28-03-2018 IPR003399 Mce/MlaD hmeg3_RS06970 1f151b5fbbec955457c0d287c867c5d1 540 Pfam PF02470 MlaD protein 50 140 3.0E-12 T 28-03-2018 IPR003399 Mce/MlaD hmeg3_RS07095 1b28d4f35eee4488e4c2d685961dcafe 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 277 1.4E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS07095 1b28d4f35eee4488e4c2d685961dcafe 284 SUPERFAMILY SSF161098 83 268 1.7E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS07095 1b28d4f35eee4488e4c2d685961dcafe 284 Gene3D G3DSA:1.10.3720.10 17 270 2.1E-22 T 28-03-2018 hmeg3_RS23915 3b486dc10358888c59e7ce3d1e81b264 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 71 3.4E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain hmeg3_RS23915 3b486dc10358888c59e7ce3d1e81b264 96 SUPERFAMILY SSF54909 4 83 8.23E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS23915 3b486dc10358888c59e7ce3d1e81b264 96 Gene3D G3DSA:3.30.70.100 1 91 8.0E-20 T 28-03-2018 hmeg3_RS00565 4e735b2d66b00f06e5a9084c82f5a6a8 177 Gene3D G3DSA:3.90.960.10 1 173 1.0E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS00565 4e735b2d66b00f06e5a9084c82f5a6a8 177 SUPERFAMILY SSF55826 16 162 3.79E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS00565 4e735b2d66b00f06e5a9084c82f5a6a8 177 Pfam PF04073 Aminoacyl-tRNA editing domain 37 152 1.4E-24 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 Gene3D G3DSA:3.60.15.10 1 246 1.8E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 Gene3D G3DSA:3.40.250.10 250 358 8.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 Pfam PF00753 Metallo-beta-lactamase superfamily 14 173 1.4E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 SUPERFAMILY SSF52821 239 352 4.98E-29 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 SMART SM00450 253 350 2.4E-22 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 SMART SM00849 12 173 2.6E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 SUPERFAMILY SSF56281 1 228 6.09E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS23950 e4f69fe61c86daa930e73e0a33e81f53 358 Pfam PF00581 Rhodanese-like domain 264 346 6.8E-14 T 28-03-2018 IPR001763 Rhodanese-like domain hmeg3_RS02460 3affab999500809e7a142c16f33ae236 141 Pfam PF13380 CoA binding domain 11 132 9.9E-36 T 28-03-2018 IPR003781 CoA-binding GO:0048037 hmeg3_RS02460 3affab999500809e7a142c16f33ae236 141 Gene3D G3DSA:3.40.50.720 6 136 4.9E-27 T 28-03-2018 hmeg3_RS02460 3affab999500809e7a142c16f33ae236 141 SMART SM00881 4 106 5.9E-10 T 28-03-2018 IPR003781 CoA-binding GO:0048037 hmeg3_RS02460 3affab999500809e7a142c16f33ae236 141 SUPERFAMILY SSF51735 10 133 1.42E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS23745 45c2cb840bcef1fc597d1fd0d2b2b9a7 258 Pfam PF13827 Domain of unknown function (DUF4189) 28 123 5.6E-17 T 28-03-2018 IPR025240 Domain of unknown function DUF4189 hmeg3_RS23745 45c2cb840bcef1fc597d1fd0d2b2b9a7 258 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 41 110 0.003 T 28-03-2018 hmeg3_RS03365 d01f929a4e9ed8f2d4822f965c9f5ace 224 SUPERFAMILY SSF52540 1 208 4.2E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS03365 d01f929a4e9ed8f2d4822f965c9f5ace 224 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 182 1.4E-14 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain hmeg3_RS03365 d01f929a4e9ed8f2d4822f965c9f5ace 224 Gene3D G3DSA:3.40.50.300 74 209 2.0E-15 T 28-03-2018 hmeg3_RS03365 d01f929a4e9ed8f2d4822f965c9f5ace 224 PIRSF PIRSF009320 1 208 1.5E-29 T 28-03-2018 hmeg3_RS03365 d01f929a4e9ed8f2d4822f965c9f5ace 224 Gene3D G3DSA:3.40.50.300 1 73 1.3E-17 T 28-03-2018 hmeg3_RS15510 41cf121a2f86334dee7eebf43c6e04e7 64 Pfam PF04384 Iron-sulphur cluster assembly 1 64 1.5E-33 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 hmeg3_RS15510 41cf121a2f86334dee7eebf43c6e04e7 64 Gene3D G3DSA:1.10.10.600 1 62 2.8E-34 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 hmeg3_RS15510 41cf121a2f86334dee7eebf43c6e04e7 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 8.3E-35 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 hmeg3_RS15510 41cf121a2f86334dee7eebf43c6e04e7 64 PIRSF PIRSF039003 1 64 3.1E-35 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 hmeg3_RS15510 41cf121a2f86334dee7eebf43c6e04e7 64 SUPERFAMILY SSF140319 1 62 2.48E-27 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 hmeg3_RS05995 780f920a2cfc77e95d3c158603f29705 304 SUPERFAMILY SSF88713 5 287 5.78E-55 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS05995 780f920a2cfc77e95d3c158603f29705 304 Gene3D G3DSA:3.20.20.370 8 299 6.1E-40 T 28-03-2018 hmeg3_RS05670 454129e8cbabf7ca01cceb8334cd4413 478 Gene3D G3DSA:1.20.1600.10 12 461 2.4E-99 T 28-03-2018 hmeg3_RS05670 454129e8cbabf7ca01cceb8334cd4413 478 Pfam PF02321 Outer membrane efflux protein 58 244 1.3E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS05670 454129e8cbabf7ca01cceb8334cd4413 478 Pfam PF02321 Outer membrane efflux protein 276 438 6.4E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS05670 454129e8cbabf7ca01cceb8334cd4413 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 4 458 3.2E-138 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS05670 454129e8cbabf7ca01cceb8334cd4413 478 SUPERFAMILY SSF56954 2 459 3.27E-107 T 28-03-2018 hmeg3_RS07790 0f920df33268f985593f140c02171713 164 Pfam PF00583 Acetyltransferase (GNAT) family 18 132 2.1E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS07790 0f920df33268f985593f140c02171713 164 Gene3D G3DSA:3.40.630.30 1 152 2.8E-15 T 28-03-2018 hmeg3_RS07790 0f920df33268f985593f140c02171713 164 SUPERFAMILY SSF55729 2 133 2.61E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS21795 f320767b2406770f00eb129e5707ff08 401 PIRSF PIRSF000355 51 401 5.6E-133 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21795 f320767b2406770f00eb129e5707ff08 401 Gene3D G3DSA:1.10.620.20 42 382 2.8E-100 T 28-03-2018 hmeg3_RS21795 f320767b2406770f00eb129e5707ff08 401 Pfam PF00268 Ribonucleotide reductase, small chain 81 368 5.3E-84 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 hmeg3_RS21795 f320767b2406770f00eb129e5707ff08 401 SUPERFAMILY SSF47240 64 372 2.22E-94 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS12205 01875de8023cfa164900c54025fbc364 812 Gene3D G3DSA:3.40.50.1820 77 400 4.9E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12205 01875de8023cfa164900c54025fbc364 812 SUPERFAMILY SSF53474 63 387 1.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12205 01875de8023cfa164900c54025fbc364 812 Pfam PF11339 Protein of unknown function (DUF3141) 35 594 1.2E-228 T 28-03-2018 IPR024501 Protein of unknown function DUF3141 hmeg3_RS15255 0e2e3c805b38d07afbcbeacebe4283dc 260 SMART SM00382 35 223 8.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS15255 0e2e3c805b38d07afbcbeacebe4283dc 260 Gene3D G3DSA:3.40.50.300 7 235 2.3E-47 T 28-03-2018 hmeg3_RS15255 0e2e3c805b38d07afbcbeacebe4283dc 260 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS15255 0e2e3c805b38d07afbcbeacebe4283dc 260 Pfam PF00005 ABC transporter 26 174 2.5E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS15255 0e2e3c805b38d07afbcbeacebe4283dc 260 SUPERFAMILY SSF52540 7 224 1.63E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01715 e2326466ef0f8eb7f2b3dda1b4008874 115 Pfam PF04342 Putative member of DMT superfamily (DUF486) 8 110 1.8E-45 T 28-03-2018 IPR007437 Putative member of DMT superfamily hmeg3_RS01715 e2326466ef0f8eb7f2b3dda1b4008874 115 PIRSF PIRSF021239 1 113 2.3E-49 T 28-03-2018 IPR007437 Putative member of DMT superfamily hmeg3_RS19650 5aef84c15fefd7b97bed4cfb17be77eb 460 PIRSF PIRSF006603 8 457 4.8E-60 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS19650 5aef84c15fefd7b97bed4cfb17be77eb 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 424 1.7E-73 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS19650 5aef84c15fefd7b97bed4cfb17be77eb 460 Pfam PF01554 MatE 16 175 1.1E-26 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS19650 5aef84c15fefd7b97bed4cfb17be77eb 460 Pfam PF01554 MatE 243 403 1.7E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 Gene3D G3DSA:1.20.1250.20 262 519 4.7E-25 T 28-03-2018 hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 Gene3D G3DSA:1.20.1250.20 21 207 4.1E-31 T 28-03-2018 hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 Pfam PF07690 Major Facilitator Superfamily 27 419 1.5E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 503 8.5E-151 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 SUPERFAMILY SSF103473 10 205 1.96E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 SUPERFAMILY SSF103473 482 507 1.96E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS12850 30e7c98ccdfc06132785c59644fbba4e 521 SUPERFAMILY SSF103473 258 429 1.96E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 SUPERFAMILY SSF48024 16 127 1.18E-38 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 Gene3D G3DSA:1.10.860.10 8 160 3.7E-47 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 18 457 4.3E-177 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 Pfam PF00772 DnaB-like helicase N terminal domain 18 119 1.3E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 SUPERFAMILY SSF52540 196 449 1.3E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 Gene3D G3DSA:3.40.50.300 178 462 5.9E-64 T 28-03-2018 hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 Pfam PF03796 DnaB-like helicase C terminal domain 198 456 5.0E-113 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 hmeg3_RS08400 9c9a2f0a8ff05f1f9f2ff1befd4349ce 468 SMART SM00382 215 416 5.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS17110 035924d2155138d9c252b1a1860bf843 184 SUPERFAMILY SSF54534 2 140 1.96E-28 T 28-03-2018 hmeg3_RS17110 035924d2155138d9c252b1a1860bf843 184 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 83 4.0E-6 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain hmeg3_RS17110 035924d2155138d9c252b1a1860bf843 184 Gene3D G3DSA:3.10.50.40 1 167 8.4E-22 T 28-03-2018 hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 SUPERFAMILY SSF51735 12 255 9.19E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 255 2.0E-59 T 28-03-2018 hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 Gene3D G3DSA:3.40.50.720 54 256 1.4E-54 T 28-03-2018 hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 Gene3D G3DSA:3.40.50.720 5 53 7.2E-10 T 28-03-2018 hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04520 094a46921613b32bcff0c9f953607f92 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS15025 2ac37fae050b2f86ab7c33678d4994bb 538 PIRSF PIRSF006446 3 525 3.8E-146 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 hmeg3_RS15025 2ac37fae050b2f86ab7c33678d4994bb 538 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 504 7.0E-175 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 hmeg3_RS08735 2a1a2f556ec415eaabf3ad65bb6c3f47 344 SUPERFAMILY SSF51621 26 263 2.65E-40 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS08735 2a1a2f556ec415eaabf3ad65bb6c3f47 344 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 48 255 1.8E-12 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 hmeg3_RS08735 2a1a2f556ec415eaabf3ad65bb6c3f47 344 Gene3D G3DSA:3.20.20.60 1 267 3.3E-39 T 28-03-2018 hmeg3_RS02765 00a170cfd6a041774d065c3ea6cbc5a1 146 Gene3D G3DSA:3.10.129.10 2 143 1.9E-40 T 28-03-2018 hmeg3_RS02765 00a170cfd6a041774d065c3ea6cbc5a1 146 SUPERFAMILY SSF54637 10 143 2.18E-40 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS02765 00a170cfd6a041774d065c3ea6cbc5a1 146 Pfam PF03061 Thioesterase superfamily 29 111 3.5E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS11945 1be7bbbedda407a630e90d6346da2eee 447 Gene3D G3DSA:1.10.3080.10 2 406 2.1E-62 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS11945 1be7bbbedda407a630e90d6346da2eee 447 PRINTS PR00762 Chloride channel signature 102 121 5.2E-6 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS11945 1be7bbbedda407a630e90d6346da2eee 447 PRINTS PR00762 Chloride channel signature 153 172 5.2E-6 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS11945 1be7bbbedda407a630e90d6346da2eee 447 Pfam PF00654 Voltage gated chloride channel 61 392 2.5E-64 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS11945 1be7bbbedda407a630e90d6346da2eee 447 SUPERFAMILY SSF81340 5 402 3.27E-89 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 hmeg3_RS09705 87cf3b35f80d518ee223898008130695 258 Gene3D G3DSA:1.10.443.10 59 252 2.7E-23 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS09705 87cf3b35f80d518ee223898008130695 258 Pfam PF00589 Phage integrase family 64 247 4.2E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 hmeg3_RS09705 87cf3b35f80d518ee223898008130695 258 SUPERFAMILY SSF56349 59 251 2.3E-37 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 hmeg3_RS09705 87cf3b35f80d518ee223898008130695 258 SUPERFAMILY SSF47823 1 56 3.92E-9 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 Gene3D G3DSA:3.40.50.200 139 479 1.9E-50 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 SUPERFAMILY SSF52743 186 476 1.57E-50 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 Pfam PF00082 Subtilase family 202 454 1.9E-27 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 221 2.4E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 420 436 2.4E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 240 253 2.4E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related hmeg3_RS13080 1b598361e6ba77260fad8ec9d5f4918f 480 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 421 431 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site hmeg3_RS09475 56c3ee5a37939466e84c24bf6982481b 404 Gene3D G3DSA:1.20.1250.20 220 398 1.4E-18 T 28-03-2018 hmeg3_RS09475 56c3ee5a37939466e84c24bf6982481b 404 SUPERFAMILY SSF103473 17 400 4.71E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS09475 56c3ee5a37939466e84c24bf6982481b 404 Pfam PF07690 Major Facilitator Superfamily 32 206 1.2E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS09475 56c3ee5a37939466e84c24bf6982481b 404 Pfam PF07690 Major Facilitator Superfamily 228 390 3.8E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS09475 56c3ee5a37939466e84c24bf6982481b 404 Gene3D G3DSA:1.20.1250.20 18 217 1.1E-23 T 28-03-2018 hmeg3_RS03790 ad295dbb7c56e731de7c380a6ba9fb84 441 Gene3D G3DSA:3.50.50.60 8 440 1.1E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03790 ad295dbb7c56e731de7c380a6ba9fb84 441 SUPERFAMILY SSF51905 373 431 1.81E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03790 ad295dbb7c56e731de7c380a6ba9fb84 441 SUPERFAMILY SSF51905 18 231 1.81E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03790 ad295dbb7c56e731de7c380a6ba9fb84 441 Pfam PF01266 FAD dependent oxidoreductase 19 412 6.8E-75 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS11480 9d3531848390a0407d8f815737c54742 145 SUPERFAMILY SSF52402 1 145 1.34E-32 T 28-03-2018 hmeg3_RS11480 9d3531848390a0407d8f815737c54742 145 Pfam PF00582 Universal stress protein family 1 145 5.1E-29 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS11480 9d3531848390a0407d8f815737c54742 145 Gene3D G3DSA:3.40.50.620 1 145 1.2E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS11480 9d3531848390a0407d8f815737c54742 145 PRINTS PR01438 Universal stress protein signature 123 145 2.9E-15 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11480 9d3531848390a0407d8f815737c54742 145 PRINTS PR01438 Universal stress protein signature 2 20 2.9E-15 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11480 9d3531848390a0407d8f815737c54742 145 PRINTS PR01438 Universal stress protein signature 105 117 2.9E-15 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 Gene3D G3DSA:1.10.287.110 1 85 3.4E-10 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 Gene3D G3DSA:1.20.1280.20 86 168 1.7E-25 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 14 163 3.0E-33 T 28-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 Pfam PF07743 HSCB C-terminal oligomerisation domain 88 162 5.7E-22 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 SUPERFAMILY SSF47144 78 164 1.31E-24 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 2 170 23.442 T 28-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 SUPERFAMILY SSF46565 3 75 4.06E-17 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS15530 63d820a25367ad64c95cc3d81e375039 171 SMART SM00271 2 67 2.4E-4 T 28-03-2018 IPR001623 DnaJ domain hmeg3_RS15770 e01318dd8139db7be7949e97300ea558 372 Pfam PF09599 Salmonella-Shigella invasin protein C (IpaC_SipC) 112 360 2.6E-8 T 28-03-2018 IPR005427 Salmonella/Shigella invasin protein C GO:0009405 hmeg3_RS13610 8eaa3005bb93fb56675376526271517c 440 PIRSF PIRSF005348 5 440 7.0E-162 T 28-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 hmeg3_RS13610 8eaa3005bb93fb56675376526271517c 440 Pfam PF03390 2-hydroxycarboxylate transporter family 24 434 1.4E-152 T 28-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 hmeg3_RS09950 362af55822e5e9a670cb58e63eb324e9 186 SUPERFAMILY SSF55194 5 184 5.89E-69 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 hmeg3_RS09950 362af55822e5e9a670cb58e63eb324e9 186 Pfam PF01765 Ribosome recycling factor 22 184 3.7E-62 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 hmeg3_RS09950 362af55822e5e9a670cb58e63eb324e9 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.732 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 hmeg3_RS09950 362af55822e5e9a670cb58e63eb324e9 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 186 2.4E-66 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 hmeg3_RS09950 362af55822e5e9a670cb58e63eb324e9 186 Gene3D G3DSA:1.10.132.20 75 185 1.4E-38 T 28-03-2018 hmeg3_RS09950 362af55822e5e9a670cb58e63eb324e9 186 Gene3D G3DSA:1.10.132.20 3 74 4.0E-9 T 28-03-2018 hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 SUPERFAMILY SSF46785 3 127 6.22E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 Pfam PF01047 MarR family 30 88 5.0E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 Gene3D G3DSA:1.10.10.10 3 138 6.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 SMART SM00347 23 122 1.1E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 2.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 2.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15100 ac76005bb8ce0df8b04c08e54a035c04 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 2.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06620 1f0a6dfd8b67808d502d1a2f5cd65373 188 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 7 180 2.5E-46 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS06620 1f0a6dfd8b67808d502d1a2f5cd65373 188 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 38 52 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 hmeg3_RS06620 1f0a6dfd8b67808d502d1a2f5cd65373 188 Gene3D G3DSA:3.30.70.1560 83 160 1.6E-20 T 28-03-2018 hmeg3_RS06620 1f0a6dfd8b67808d502d1a2f5cd65373 188 Gene3D G3DSA:3.30.70.580 2 82 7.2E-19 T 28-03-2018 hmeg3_RS06620 1f0a6dfd8b67808d502d1a2f5cd65373 188 Pfam PF00849 RNA pseudouridylate synthase 3 148 9.4E-15 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS06620 1f0a6dfd8b67808d502d1a2f5cd65373 188 SUPERFAMILY SSF55120 3 183 3.36E-39 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 hmeg3_RS23100 577fc7608054fbb7ee17ffd525f4dc66 338 Gene3D G3DSA:3.40.190.10 26 139 3.4E-12 T 28-03-2018 hmeg3_RS23100 577fc7608054fbb7ee17ffd525f4dc66 338 SUPERFAMILY SSF53850 39 274 2.9E-35 T 28-03-2018 hmeg3_RS23100 577fc7608054fbb7ee17ffd525f4dc66 338 Pfam PF13379 NMT1-like family 29 271 1.8E-25 T 28-03-2018 hmeg3_RS23100 577fc7608054fbb7ee17ffd525f4dc66 338 Gene3D G3DSA:3.40.190.10 140 335 2.7E-20 T 28-03-2018 hmeg3_RS16860 5233bbc71f941ea0cf52018cbd868079 392 SUPERFAMILY SSF102114 80 292 2.62E-10 T 28-03-2018 hmeg3_RS16860 5233bbc71f941ea0cf52018cbd868079 392 SMART SM00729 94 319 1.7E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 hmeg3_RS16860 5233bbc71f941ea0cf52018cbd868079 392 Pfam PF04055 Radical SAM superfamily 99 276 4.3E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS16860 5233bbc71f941ea0cf52018cbd868079 392 Gene3D G3DSA:3.20.20.70 71 365 6.1E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS07835 65adc1ef0b60ee55650aed99f79c4b7f 792 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 93 274 6.8E-6 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 hmeg3_RS07835 65adc1ef0b60ee55650aed99f79c4b7f 792 Gene3D G3DSA:3.20.20.80 73 526 2.4E-36 T 28-03-2018 hmeg3_RS07835 65adc1ef0b60ee55650aed99f79c4b7f 792 SUPERFAMILY SSF51445 358 503 7.04E-25 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS07835 65adc1ef0b60ee55650aed99f79c4b7f 792 SUPERFAMILY SSF51445 90 255 7.04E-25 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 7.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 7.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 SUPERFAMILY SSF51735 4 234 9.24E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 Pfam PF00106 short chain dehydrogenase 8 201 6.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS09500 eb10bf9080b70ddc7b0f2dc955551187 255 Gene3D G3DSA:3.40.50.720 1 203 6.0E-56 T 28-03-2018 hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 SUPERFAMILY SSF57863 142 227 9.42E-11 T 28-03-2018 hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 Gene3D G3DSA:2.40.50.140 57 138 7.7E-25 T 28-03-2018 hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 Pfam PF11967 Recombination protein O N terminal 62 134 1.9E-23 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 TIGRFAM TIGR00613 reco: DNA repair protein RecO 63 212 3.2E-30 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 Pfam PF02565 Recombination protein O C terminal 142 282 7.9E-20 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 Hamap MF_00201 DNA repair protein RecO [recO]. 58 288 23.948 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 hmeg3_RS16670 6267403dd5086283b685f73a410b2e6b 291 SUPERFAMILY SSF50249 59 133 3.6E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS14175 d327d0ee2a9f17539355aa7b8fb1346b 277 Gene3D G3DSA:1.10.3720.10 12 275 7.0E-38 T 28-03-2018 hmeg3_RS14175 d327d0ee2a9f17539355aa7b8fb1346b 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 275 5.6E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14175 d327d0ee2a9f17539355aa7b8fb1346b 277 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 51 2.2E-7 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS14175 d327d0ee2a9f17539355aa7b8fb1346b 277 SUPERFAMILY SSF161098 70 274 3.27E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12065 a601b673aced8e3229698df57ebde329 303 SUPERFAMILY SSF53474 29 302 1.53E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12065 a601b673aced8e3229698df57ebde329 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 134 147 1.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12065 a601b673aced8e3229698df57ebde329 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12065 a601b673aced8e3229698df57ebde329 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 91 1.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12065 a601b673aced8e3229698df57ebde329 303 Pfam PF12697 Alpha/beta hydrolase family 53 296 1.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12065 a601b673aced8e3229698df57ebde329 303 Gene3D G3DSA:3.40.50.1820 25 303 1.4E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 SMART SM00346 37 125 1.8E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 Pfam PF09339 IclR helix-turn-helix domain 39 86 1.0E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 Gene3D G3DSA:3.30.450.40 109 282 2.5E-33 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 Pfam PF01614 Bacterial transcriptional regulator 156 257 3.2E-10 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 SUPERFAMILY SSF46785 39 105 1.48E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 SUPERFAMILY SSF55781 100 275 1.57E-31 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS21085 d0f1d0f83e65b73d1e9d060ac4012ed4 286 Gene3D G3DSA:1.10.10.10 21 96 5.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 Pfam PF00285 Citrate synthase, C-terminal domain 20 368 2.5E-112 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 ProSitePatterns PS00480 Citrate synthase signature. 269 281 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 SUPERFAMILY SSF48256 20 379 1.14E-123 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PRINTS PR00143 Citrate synthase signature 187 202 1.3E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PRINTS PR00143 Citrate synthase signature 319 335 1.3E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PRINTS PR00143 Citrate synthase signature 209 237 1.3E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PRINTS PR00143 Citrate synthase signature 262 282 1.3E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PRINTS PR00143 Citrate synthase signature 339 353 1.3E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PRINTS PR00143 Citrate synthase signature 137 150 1.3E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 PIRSF PIRSF001369 13 387 1.6E-111 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 19 386 5.9E-158 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 hmeg3_RS15435 dfe5da37b7a844497b0f26f2d70fdb45 387 Gene3D G3DSA:1.10.580.10 26 366 1.6E-81 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain hmeg3_RS23110 9e50dd1d073aa70c3759c19e9c87f63b 278 Gene3D G3DSA:3.40.50.300 10 268 5.8E-57 T 28-03-2018 hmeg3_RS23110 9e50dd1d073aa70c3759c19e9c87f63b 278 Pfam PF00005 ABC transporter 34 175 1.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS23110 9e50dd1d073aa70c3759c19e9c87f63b 278 SMART SM00382 42 223 8.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS23110 9e50dd1d073aa70c3759c19e9c87f63b 278 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS23110 9e50dd1d073aa70c3759c19e9c87f63b 278 SUPERFAMILY SSF52540 14 233 1.77E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 Gene3D G3DSA:3.40.50.880 1 191 2.0E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 185 1.8E-82 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 Pfam PF00117 Glutamine amidotransferase class-I 4 185 1.8E-55 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.1E-35 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.1E-35 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.1E-35 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.1E-35 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.1E-35 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.1E-35 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 6.0E-6 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 6.0E-6 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.3E-13 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 28-03-2018 hmeg3_RS04445 891ae794349600337054bff8b4ec3a94 191 SUPERFAMILY SSF52317 1 186 1.83E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS00475 ce0fdb5873d060f76ccd76ee4f613368 383 Pfam PF13458 Periplasmic binding protein 30 371 4.1E-47 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS00475 ce0fdb5873d060f76ccd76ee4f613368 383 SUPERFAMILY SSF53822 30 377 3.06E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS00475 ce0fdb5873d060f76ccd76ee4f613368 383 Gene3D G3DSA:3.40.50.2300 27 361 2.2E-52 T 28-03-2018 hmeg3_RS11730 f14f94b191e54be0d1bc6db86f2acc8a 388 Pfam PF01145 SPFH domain / Band 7 family 50 236 1.9E-18 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS11730 f14f94b191e54be0d1bc6db86f2acc8a 388 SMART SM00244 46 220 0.0014 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS11730 f14f94b191e54be0d1bc6db86f2acc8a 388 SUPERFAMILY SSF117892 82 224 1.57E-11 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS18400 d3a611bd9c0124649767d782ffba09b5 152 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 147 1.4E-23 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19870 b6615cd4239769f1c6d15a2e15f91116 307 Pfam PF01863 Protein of unknown function DUF45 90 298 2.7E-60 T 28-03-2018 IPR002725 Protein of unknown function DUF45 hmeg3_RS09480 2f7c4b9f1ed8f70f3ee77dd07e59dcae 335 Gene3D G3DSA:3.40.190.10 22 136 2.7E-14 T 28-03-2018 hmeg3_RS09480 2f7c4b9f1ed8f70f3ee77dd07e59dcae 335 Gene3D G3DSA:3.40.190.10 137 334 5.4E-21 T 28-03-2018 hmeg3_RS09480 2f7c4b9f1ed8f70f3ee77dd07e59dcae 335 Pfam PF13379 NMT1-like family 24 266 1.0E-28 T 28-03-2018 hmeg3_RS09480 2f7c4b9f1ed8f70f3ee77dd07e59dcae 335 SUPERFAMILY SSF53850 26 283 3.16E-26 T 28-03-2018 hmeg3_RS22365 70aa9d68d143b41420fbc533a3efb8c8 124 PIRSF PIRSF016821 1 124 1.3E-40 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 hmeg3_RS22365 70aa9d68d143b41420fbc533a3efb8c8 124 SUPERFAMILY SSF55174 3 100 9.03E-27 T 28-03-2018 hmeg3_RS22365 70aa9d68d143b41420fbc533a3efb8c8 124 SMART SM00363 4 67 1.4E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS22365 70aa9d68d143b41420fbc533a3efb8c8 124 Gene3D G3DSA:3.10.290.10 1 99 3.6E-23 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS22365 70aa9d68d143b41420fbc533a3efb8c8 124 Pfam PF01479 S4 domain 5 49 1.6E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 hmeg3_RS03240 e51afe60e66b08b4d0935c983ffebb29 163 Pfam PF04314 Copper chaperone PCu(A)C 32 140 4.9E-39 T 28-03-2018 IPR007410 Copper chaperone PCuAC hmeg3_RS03240 e51afe60e66b08b4d0935c983ffebb29 163 SUPERFAMILY SSF110087 6 147 1.83E-47 T 28-03-2018 IPR007410 Copper chaperone PCuAC hmeg3_RS10990 5b0c1c5c07406b6a2fad200d5c79ba14 304 SUPERFAMILY SSF51695 27 299 2.88E-49 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 hmeg3_RS10990 5b0c1c5c07406b6a2fad200d5c79ba14 304 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 32 294 8.2E-24 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 hmeg3_RS10990 5b0c1c5c07406b6a2fad200d5c79ba14 304 Gene3D G3DSA:3.20.20.190 22 304 4.3E-48 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 hmeg3_RS10065 ec6c0ac8ff93b738bf24efb0f196ccd6 143 Gene3D G3DSA:3.30.530.20 1 143 1.5E-29 T 28-03-2018 IPR023393 START-like domain hmeg3_RS10065 ec6c0ac8ff93b738bf24efb0f196ccd6 143 SUPERFAMILY SSF55961 1 143 2.85E-33 T 28-03-2018 hmeg3_RS10065 ec6c0ac8ff93b738bf24efb0f196ccd6 143 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 2.4E-29 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 hmeg3_RS00620 051ed1002dead6417fd08828ec1951bd 355 SUPERFAMILY SSF56281 15 351 3.93E-71 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00620 051ed1002dead6417fd08828ec1951bd 355 Gene3D G3DSA:3.60.15.10 15 289 2.5E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00620 051ed1002dead6417fd08828ec1951bd 355 SMART SM00849 42 267 9.6E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS00620 051ed1002dead6417fd08828ec1951bd 355 Pfam PF00753 Metallo-beta-lactamase superfamily 60 267 7.5E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 Gene3D G3DSA:1.10.287.70 584 649 2.7E-10 T 28-03-2018 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 Gene3D G3DSA:1.20.210.10 53 571 1.9E-187 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 SUPERFAMILY SSF81442 53 570 1.05E-179 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 12 656 0.0 T 28-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 66 514 1.3E-137 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 290 344 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 379 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 471 492 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 411 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 188 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 226 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 130 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 134 158 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 349 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 440 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 57 82 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS11250 c6892e5eff5823b23a1cc7dd0772534d 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 256 2.0E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS06275 acd31dea77e2781ef9ff3f03cf1aa0ea 395 Gene3D G3DSA:1.20.1250.20 199 395 2.8E-23 T 28-03-2018 hmeg3_RS06275 acd31dea77e2781ef9ff3f03cf1aa0ea 395 Gene3D G3DSA:1.20.1250.20 11 198 1.7E-17 T 28-03-2018 hmeg3_RS06275 acd31dea77e2781ef9ff3f03cf1aa0ea 395 SUPERFAMILY SSF103473 11 390 2.49E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS06275 acd31dea77e2781ef9ff3f03cf1aa0ea 395 Pfam PF07690 Major Facilitator Superfamily 22 356 4.2E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS14360 17f23983b828ff1a01d979e973b73358 202 Pfam PF03942 DTW domain 1 188 5.8E-43 T 28-03-2018 IPR005636 DTW hmeg3_RS14360 17f23983b828ff1a01d979e973b73358 202 SMART SM01144 1 193 3.6E-55 T 28-03-2018 IPR005636 DTW hmeg3_RS04820 20dabbdb4c9f42ff95e7d60980521aa4 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 27 179 4.0E-56 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 hmeg3_RS04820 20dabbdb4c9f42ff95e7d60980521aa4 190 Gene3D G3DSA:1.20.1200.10 17 183 2.5E-65 T 28-03-2018 hmeg3_RS04820 20dabbdb4c9f42ff95e7d60980521aa4 190 Pfam PF01923 Cobalamin adenosyltransferase 8 165 9.4E-59 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 hmeg3_RS04820 20dabbdb4c9f42ff95e7d60980521aa4 190 SUPERFAMILY SSF89028 7 178 9.42E-62 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 hmeg3_RS04820 20dabbdb4c9f42ff95e7d60980521aa4 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 178 2.0E-62 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 hmeg3_RS10800 42a551ac94947d38b7e71cb9e1535696 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 hmeg3_RS10800 42a551ac94947d38b7e71cb9e1535696 260 Gene3D G3DSA:3.90.226.10 3 220 2.6E-64 T 28-03-2018 hmeg3_RS10800 42a551ac94947d38b7e71cb9e1535696 260 Gene3D G3DSA:1.10.12.10 221 258 3.6E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS10800 42a551ac94947d38b7e71cb9e1535696 260 SUPERFAMILY SSF52096 2 259 1.24E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS10800 42a551ac94947d38b7e71cb9e1535696 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 259 2.0E-55 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS06345 1dd348a41f4626fa4734afdc8131092e 439 Gene3D G3DSA:1.20.1250.20 14 225 4.9E-38 T 28-03-2018 hmeg3_RS06345 1dd348a41f4626fa4734afdc8131092e 439 Gene3D G3DSA:1.20.1250.20 238 434 7.7E-25 T 28-03-2018 hmeg3_RS06345 1dd348a41f4626fa4734afdc8131092e 439 SUPERFAMILY SSF103473 13 430 1.44E-84 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS06345 1dd348a41f4626fa4734afdc8131092e 439 Pfam PF07690 Major Facilitator Superfamily 30 392 1.2E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS20780 5d5fbe22cee63739a15c0e258c13c50f 428 Gene3D G3DSA:3.40.50.1820 53 428 5.1E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20780 5d5fbe22cee63739a15c0e258c13c50f 428 PIRSF PIRSF000443 34 428 2.6E-95 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 hmeg3_RS20780 5d5fbe22cee63739a15c0e258c13c50f 428 SUPERFAMILY SSF53474 65 426 1.46E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20780 5d5fbe22cee63739a15c0e258c13c50f 428 Pfam PF00561 alpha/beta hydrolase fold 172 392 3.2E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS21545 4017e28268e71163a3588513a5d03791 269 Hamap MF_00443 Thiazole synthase [thiG]. 14 269 41.987 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 hmeg3_RS21545 4017e28268e71163a3588513a5d03791 269 SUPERFAMILY SSF110399 15 255 2.75E-89 T 28-03-2018 hmeg3_RS21545 4017e28268e71163a3588513a5d03791 269 Gene3D G3DSA:3.20.20.70 13 269 6.0E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS21545 4017e28268e71163a3588513a5d03791 269 Pfam PF05690 Thiazole biosynthesis protein ThiG 17 263 8.6E-108 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 hmeg3_RS10030 80c21048a2f43b47888c6aa9db003c8c 147 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 143 9.9E-6 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain hmeg3_RS15395 2f907ace32fb281e28c36d997658ca48 133 SUPERFAMILY SSF51182 16 120 4.8E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS15395 2f907ace32fb281e28c36d997658ca48 133 Gene3D G3DSA:2.60.120.10 13 131 3.2E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS15395 2f907ace32fb281e28c36d997658ca48 133 Pfam PF07883 Cupin domain 50 109 3.1E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS19355 22adf2c08fd1c839952ddef02f4f7c0f 119 Gene3D G3DSA:1.10.700.10 5 117 6.9E-33 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit hmeg3_RS19355 22adf2c08fd1c839952ddef02f4f7c0f 119 SUPERFAMILY SSF48076 1 117 2.62E-36 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit hmeg3_RS19355 22adf2c08fd1c839952ddef02f4f7c0f 119 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 28 114 2.3E-27 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit hmeg3_RS05165 f987cc4f5253819395eadf1fef375ddf 213 Pfam PF13681 Type IV pilus assembly protein PilX C-term 96 184 7.5E-11 T 28-03-2018 IPR025205 PilX/PilW C-terminal domain hmeg3_RS05165 f987cc4f5253819395eadf1fef375ddf 213 Pfam PF14341 PilX N-terminal 8 58 6.8E-13 T 28-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain hmeg3_RS17680 f285a552210a044bddc06fd99505d6a7 310 Pfam PF05853 beta-keto acid cleavage enzyme 6 302 7.3E-105 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 hmeg3_RS17680 f285a552210a044bddc06fd99505d6a7 310 Gene3D G3DSA:3.20.20.70 4 306 3.6E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS23855 0a656281dfbbe610d8e933e48cf31a13 362 SUPERFAMILY SSF51395 1 351 1.13E-109 T 28-03-2018 hmeg3_RS23855 0a656281dfbbe610d8e933e48cf31a13 362 Gene3D G3DSA:3.20.20.70 1 353 1.2E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS23855 0a656281dfbbe610d8e933e48cf31a13 362 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 337 9.1E-66 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 hmeg3_RS14475 3e42caadba420afc4127de83b44bd027 196 Gene3D G3DSA:3.40.50.360 1 186 4.5E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS14475 3e42caadba420afc4127de83b44bd027 196 Pfam PF03358 NADPH-dependent FMN reductase 1 138 1.7E-30 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS14475 3e42caadba420afc4127de83b44bd027 196 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 2 170 5.1E-65 T 28-03-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 hmeg3_RS14475 3e42caadba420afc4127de83b44bd027 196 SUPERFAMILY SSF52218 1 169 4.66E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS20230 b429d2d59549c57ba458c45888dd8dc9 313 Pfam PF01841 Transglutaminase-like superfamily 152 257 1.4E-18 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS20230 b429d2d59549c57ba458c45888dd8dc9 313 SUPERFAMILY SSF54001 93 284 7.07E-41 T 28-03-2018 hmeg3_RS20230 b429d2d59549c57ba458c45888dd8dc9 313 Gene3D G3DSA:3.90.260.10 169 265 2.5E-6 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS20230 b429d2d59549c57ba458c45888dd8dc9 313 SMART SM00460 184 259 1.2E-16 T 28-03-2018 IPR002931 Transglutaminase-like hmeg3_RS20230 b429d2d59549c57ba458c45888dd8dc9 313 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 8 88 1.4E-22 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal hmeg3_RS05245 62d5a9036598cc516479cd616ec9dd56 237 Pfam PF00005 ABC transporter 20 164 4.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS05245 62d5a9036598cc516479cd616ec9dd56 237 Gene3D G3DSA:3.40.50.300 1 235 4.5E-51 T 28-03-2018 hmeg3_RS05245 62d5a9036598cc516479cd616ec9dd56 237 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 235 3.6E-10 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal hmeg3_RS05245 62d5a9036598cc516479cd616ec9dd56 237 SMART SM00382 28 213 1.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS05245 62d5a9036598cc516479cd616ec9dd56 237 SUPERFAMILY SSF52540 3 235 1.55E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS21540 011759d5613c9f343ffb5bdf47f5755f 272 Gene3D G3DSA:3.40.1190.20 5 263 4.3E-51 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS21540 011759d5613c9f343ffb5bdf47f5755f 272 Pfam PF08543 Phosphomethylpyrimidine kinase 18 257 1.2E-64 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 hmeg3_RS21540 011759d5613c9f343ffb5bdf47f5755f 272 SUPERFAMILY SSF53613 8 263 2.95E-60 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS20730 bbf964055b905ba9d3d08e7279168c3f 209 Pfam PF01613 Flavin reductase like domain 23 167 6.0E-22 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS20730 bbf964055b905ba9d3d08e7279168c3f 209 Gene3D G3DSA:2.30.110.10 10 189 4.2E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS20730 bbf964055b905ba9d3d08e7279168c3f 209 SUPERFAMILY SSF50475 2 196 1.37E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS20730 bbf964055b905ba9d3d08e7279168c3f 209 SMART SM00903 20 175 4.6E-24 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS09065 1b62c2859f083542f876c6463533ec1b 133 Gene3D G3DSA:1.10.490.10 1 133 8.0E-29 T 28-03-2018 hmeg3_RS09065 1b62c2859f083542f876c6463533ec1b 133 Pfam PF01152 Bacterial-like globin 10 130 7.6E-44 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 hmeg3_RS09065 1b62c2859f083542f876c6463533ec1b 133 SUPERFAMILY SSF46458 10 130 4.73E-34 T 28-03-2018 IPR009050 Globin-like hmeg3_RS09065 1b62c2859f083542f876c6463533ec1b 133 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 59 83 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 hmeg3_RS18175 c7de54470020dcaf9ada6f21ad31ac21 415 Gene3D G3DSA:3.40.190.10 155 371 6.8E-41 T 28-03-2018 hmeg3_RS18175 c7de54470020dcaf9ada6f21ad31ac21 415 Gene3D G3DSA:3.40.190.10 42 154 3.1E-8 T 28-03-2018 hmeg3_RS18175 c7de54470020dcaf9ada6f21ad31ac21 415 SUPERFAMILY SSF53850 43 278 7.96E-29 T 28-03-2018 hmeg3_RS18175 c7de54470020dcaf9ada6f21ad31ac21 415 Pfam PF13379 NMT1-like family 40 290 6.7E-104 T 28-03-2018 hmeg3_RS13355 053d214366a6708fecee6b0b32fadac0 176 SUPERFAMILY SSF54637 5 171 1.38E-35 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS13355 053d214366a6708fecee6b0b32fadac0 176 Gene3D G3DSA:3.10.129.10 37 174 3.4E-29 T 28-03-2018 hmeg3_RS13355 053d214366a6708fecee6b0b32fadac0 176 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 79 171 2.4E-23 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 hmeg3_RS13355 053d214366a6708fecee6b0b32fadac0 176 Pfam PF03061 Thioesterase superfamily 86 162 6.7E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS03465 efc9b3feebf4261d630e305e04263e46 78 PIRSF PIRSF003113 1 78 2.4E-22 T 28-03-2018 IPR002634 BolA protein hmeg3_RS03465 efc9b3feebf4261d630e305e04263e46 78 Gene3D G3DSA:3.30.300.90 3 78 1.8E-28 T 28-03-2018 hmeg3_RS03465 efc9b3feebf4261d630e305e04263e46 78 SUPERFAMILY SSF82657 2 78 1.1E-28 T 28-03-2018 IPR002634 BolA protein hmeg3_RS03465 efc9b3feebf4261d630e305e04263e46 78 Pfam PF01722 BolA-like protein 23 75 4.0E-21 T 28-03-2018 IPR002634 BolA protein hmeg3_RS08015 bf9fcde05cf75fd7969d266e89a5f451 272 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS08015 bf9fcde05cf75fd7969d266e89a5f451 272 SMART SM00382 52 233 9.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS08015 bf9fcde05cf75fd7969d266e89a5f451 272 SUPERFAMILY SSF52540 25 247 4.33E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08015 bf9fcde05cf75fd7969d266e89a5f451 272 Pfam PF00005 ABC transporter 43 182 7.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS08015 bf9fcde05cf75fd7969d266e89a5f451 272 Gene3D G3DSA:3.40.50.300 20 242 2.5E-58 T 28-03-2018 hmeg3_RS16895 803c2cdb790afd050441174ee0323f04 394 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 46 392 1.3E-52 T 28-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 SUPERFAMILY SSF53795 249 620 8.47E-152 T 28-03-2018 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 Gene3D G3DSA:3.90.228.20 249 323 9.3E-24 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 Gene3D G3DSA:3.90.228.20 330 622 1.1E-114 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 SUPERFAMILY SSF68923 11 248 1.83E-103 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 25 245 7.4E-106 T 28-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 620 3.6E-166 T 28-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 Gene3D G3DSA:3.40.449.10 8 248 1.5E-116 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 PIRSF PIRSF001348 1 622 8.5E-281 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 28-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 hmeg3_RS02760 a64d2eed440767677e624722db6eb69a 622 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 14 621 50.787 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 hmeg3_RS04745 a372c69f510ec604fdd8b48c8e6db0a7 274 Gene3D G3DSA:3.40.1190.20 2 272 2.6E-31 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS04745 a372c69f510ec604fdd8b48c8e6db0a7 274 SUPERFAMILY SSF53613 6 267 3.48E-49 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS04745 a372c69f510ec604fdd8b48c8e6db0a7 274 Pfam PF08543 Phosphomethylpyrimidine kinase 16 258 3.1E-51 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 hmeg3_RS01565 c7554d35ddbfb6b36fe928577dd0a99c 304 SUPERFAMILY SSF103481 45 137 1.06E-9 T 28-03-2018 hmeg3_RS01565 c7554d35ddbfb6b36fe928577dd0a99c 304 SUPERFAMILY SSF103481 192 289 1.24E-7 T 28-03-2018 hmeg3_RS01565 c7554d35ddbfb6b36fe928577dd0a99c 304 Pfam PF00892 EamA-like transporter family 12 135 1.1E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS01565 c7554d35ddbfb6b36fe928577dd0a99c 304 Pfam PF00892 EamA-like transporter family 146 288 1.1E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 TIGRFAM TIGR02568 LcrE: type III secretion regulator YopN/LcrE/InvE/MxiC 47 268 2.2E-42 T 28-03-2018 IPR013401 Type III secretion regulator, YopN/LcrE/InvE/MxiC GO:0009986|GO:0030254|GO:0050709 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 SUPERFAMILY SSF140591 71 260 2.98E-38 T 28-03-2018 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 263 280 8.3E-31 T 28-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 114 133 8.3E-31 T 28-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 233 253 8.3E-31 T 28-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 207 219 8.3E-31 T 28-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 54 74 8.3E-31 T 28-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 178 196 8.3E-31 T 28-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 hmeg3_RS15835 952e53bdc32f7fb768018ffb0927e053 384 Pfam PF07201 HrpJ-like domain 58 214 8.6E-31 T 28-03-2018 IPR010812 Hypersensitivity response secretion-like, HrpJ GO:0009405|GO:0019867|GO:0046903 hmeg3_RS02985 895574050b004100c2685070116a6327 379 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 49 332 1.4E-58 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 hmeg3_RS02985 895574050b004100c2685070116a6327 379 Gene3D G3DSA:3.40.50.2300 165 379 8.8E-52 T 28-03-2018 hmeg3_RS02985 895574050b004100c2685070116a6327 379 Gene3D G3DSA:3.40.50.2300 46 164 7.1E-33 T 28-03-2018 hmeg3_RS10565 838edd21877ed7b803f3b93b9a9a4c42 267 SUPERFAMILY SSF52540 4 244 1.5E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS10565 838edd21877ed7b803f3b93b9a9a4c42 267 Pfam PF00005 ABC transporter 21 172 2.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS10565 838edd21877ed7b803f3b93b9a9a4c42 267 SMART SM00382 30 222 2.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS10565 838edd21877ed7b803f3b93b9a9a4c42 267 Gene3D G3DSA:3.40.50.300 2 246 5.1E-47 T 28-03-2018 hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 SUPERFAMILY SSF46785 10 118 1.84E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 SMART SM00347 36 132 4.4E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 Gene3D G3DSA:1.10.10.10 2 151 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 9.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 9.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 9.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS06315 2126fe718a9bae529ab9acb75c57849a 154 Pfam PF01047 MarR family 43 101 5.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 Pfam PF00813 FliP family 10 211 7.1E-62 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 8 27 2.3E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 165 186 2.3E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 189 214 2.3E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 47 66 2.3E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 144 164 2.3E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 27 47 2.3E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 192 204 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS15800 fd236c1d734fb2defb2b8897b083baf1 222 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 7 211 8.1E-77 T 28-03-2018 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.0E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 Pfam PF03466 LysR substrate binding domain 90 293 1.2E-38 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 Gene3D G3DSA:3.40.190.10 177 265 1.2E-20 T 28-03-2018 hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 Gene3D G3DSA:3.40.190.10 87 176 6.1E-17 T 28-03-2018 hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 SUPERFAMILY SSF53850 90 298 1.25E-39 T 28-03-2018 hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 Gene3D G3DSA:1.10.10.10 2 84 4.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13395 582f644de21f9950fea7962e2558788b 313 SUPERFAMILY SSF46785 3 111 5.68E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10740 b8edd3349259afa5cfcc555715663d6a 278 Pfam PF00905 Penicillin binding protein transpeptidase domain 45 263 1.1E-43 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 hmeg3_RS10740 b8edd3349259afa5cfcc555715663d6a 278 ProSitePatterns PS00337 Beta-lactamase class-D active site. 56 66 - T 28-03-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 hmeg3_RS10740 b8edd3349259afa5cfcc555715663d6a 278 Gene3D G3DSA:3.40.710.10 5 267 4.8E-26 T 28-03-2018 hmeg3_RS10740 b8edd3349259afa5cfcc555715663d6a 278 SUPERFAMILY SSF56601 44 265 1.23E-32 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS05470 cd81e9272e0989b0013b273b407760b9 431 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 28 425 2.0E-109 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 hmeg3_RS05470 cd81e9272e0989b0013b273b407760b9 431 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 350 370 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 hmeg3_RS05470 cd81e9272e0989b0013b273b407760b9 431 Pfam PF00860 Permease family 33 403 4.2E-93 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS21040 e8a6d2f4f699d823494cd6516d4ff890 291 Gene3D G3DSA:3.20.20.140 2 291 1.2E-35 T 28-03-2018 hmeg3_RS21040 e8a6d2f4f699d823494cd6516d4ff890 291 SUPERFAMILY SSF51556 6 289 2.55E-58 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS21040 e8a6d2f4f699d823494cd6516d4ff890 291 Pfam PF04909 Amidohydrolase 6 289 4.7E-29 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 hmeg3_RS11785 ed44600cb440bd5f134bf3b7e27156ed 363 SUPERFAMILY SSF46689 301 349 1.34E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS11785 ed44600cb440bd5f134bf3b7e27156ed 363 Gene3D G3DSA:1.10.10.60 237 296 0.021 T 28-03-2018 hmeg3_RS11785 ed44600cb440bd5f134bf3b7e27156ed 363 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 33 221 2.7E-17 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal hmeg3_RS11785 ed44600cb440bd5f134bf3b7e27156ed 363 Pfam PF12833 Helix-turn-helix domain 272 347 1.8E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS11785 ed44600cb440bd5f134bf3b7e27156ed 363 SMART SM00342 265 347 3.7E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS11785 ed44600cb440bd5f134bf3b7e27156ed 363 Gene3D G3DSA:1.10.10.60 297 349 2.2E-10 T 28-03-2018 hmeg3_RS16470 5863d131ac388d3f73559d65ff9f3290 370 Pfam PF12706 Beta-lactamase superfamily domain 124 327 5.5E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS16470 5863d131ac388d3f73559d65ff9f3290 370 Gene3D G3DSA:3.60.15.10 73 370 4.5E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS16470 5863d131ac388d3f73559d65ff9f3290 370 PIRSF PIRSF038896 20 370 7.1E-117 T 28-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 hmeg3_RS16470 5863d131ac388d3f73559d65ff9f3290 370 SUPERFAMILY SSF56281 105 333 6.02E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 SUPERFAMILY SSF103473 459 482 7.98E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 SUPERFAMILY SSF103473 1 185 7.98E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 SUPERFAMILY SSF103473 236 407 7.98E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 388 407 6.7E-5 T 28-03-2018 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 4 28 6.7E-5 T 28-03-2018 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 64 86 6.7E-5 T 28-03-2018 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 6.7E-5 T 28-03-2018 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 290 314 6.7E-5 T 28-03-2018 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 Pfam PF07690 Major Facilitator Superfamily 10 397 3.3E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 Gene3D G3DSA:1.20.1250.20 247 498 4.1E-25 T 28-03-2018 hmeg3_RS11155 b0d12127cbd406e788dcff417538281e 502 Gene3D G3DSA:1.20.1250.20 1 181 2.7E-31 T 28-03-2018 hmeg3_RS09570 323c3aac16db5306abdf4d066860f695 301 SUPERFAMILY SSF161098 93 283 2.75E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09570 323c3aac16db5306abdf4d066860f695 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 299 9.5E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09570 323c3aac16db5306abdf4d066860f695 301 Gene3D G3DSA:1.10.3720.10 17 289 5.3E-43 T 28-03-2018 hmeg3_RS09570 323c3aac16db5306abdf4d066860f695 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 13 56 9.8E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain hmeg3_RS08995 7334f80c84c8273cc3889372e8e3e8f6 418 Gene3D G3DSA:2.40.440.10 149 290 8.2E-24 T 28-03-2018 hmeg3_RS08995 7334f80c84c8273cc3889372e8e3e8f6 418 SUPERFAMILY SSF141523 155 290 4.58E-18 T 28-03-2018 hmeg3_RS08995 7334f80c84c8273cc3889372e8e3e8f6 418 Pfam PF03734 L,D-transpeptidase catalytic domain 156 289 6.8E-19 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 SUPERFAMILY SSF52540 13 276 3.72E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 SMART SM00382 67 238 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 ProSitePatterns PS00321 recA signature. 223 231 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 SUPERFAMILY SSF54752 278 336 4.71E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 Gene3D G3DSA:3.30.250.10 279 336 1.1E-27 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 PRINTS PR00142 RecA protein signature 137 166 5.6E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 PRINTS PR00142 RecA protein signature 307 324 5.6E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 PRINTS PR00142 RecA protein signature 253 282 5.6E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 PRINTS PR00142 RecA protein signature 220 248 5.6E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 PRINTS PR00142 RecA protein signature 175 204 5.6E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 PRINTS PR00142 RecA protein signature 103 132 5.6E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 Hamap MF_00268 Protein RecA [recA]. 14 339 51.73 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 Gene3D G3DSA:3.40.50.300 35 278 4.1E-46 T 28-03-2018 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 Pfam PF00154 recA bacterial DNA recombination protein 16 277 8.3E-142 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS20160 f203a35640841cf2eb807d3e9546a773 372 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 13 333 2.8E-170 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 hmeg3_RS01070 050784c54e430bd646006e829a842c1e 138 Gene3D G3DSA:1.10.287.180 27 58 0.4 T 28-03-2018 hmeg3_RS01070 050784c54e430bd646006e829a842c1e 138 Gene3D G3DSA:1.10.287.180 63 100 0.22 T 28-03-2018 hmeg3_RS01070 050784c54e430bd646006e829a842c1e 138 Pfam PF13663 Domain of unknown function (DUF4148) 1 61 2.1E-15 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS01070 050784c54e430bd646006e829a842c1e 138 Pfam PF13663 Domain of unknown function (DUF4148) 67 98 3.0E-10 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS01070 050784c54e430bd646006e829a842c1e 138 Pfam PF13663 Domain of unknown function (DUF4148) 105 129 1.8E-5 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS03705 5a24f0a55294b7b8784a5088dec6451e 507 SUPERFAMILY SSF75304 3 461 7.33E-125 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS03705 5a24f0a55294b7b8784a5088dec6451e 507 Pfam PF01425 Amidase 27 451 1.9E-96 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS03705 5a24f0a55294b7b8784a5088dec6451e 507 Gene3D G3DSA:3.90.1300.10 3 480 7.1E-121 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS06510 67d138bf901d1490aba34ff21cd331a8 200 SUPERFAMILY SSF54001 68 192 1.6E-40 T 28-03-2018 hmeg3_RS06510 67d138bf901d1490aba34ff21cd331a8 200 Pfam PF00877 NlpC/P60 family 85 191 4.6E-29 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain hmeg3_RS06510 67d138bf901d1490aba34ff21cd331a8 200 Gene3D G3DSA:3.90.1720.10 67 200 1.5E-38 T 28-03-2018 hmeg3_RS11680 2085569335b8b6a17cf5eb7e04f5a201 288 SUPERFAMILY SSF55729 66 260 9.44E-62 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS11680 2085569335b8b6a17cf5eb7e04f5a201 288 Pfam PF13523 Acetyltransferase (GNAT) domain 103 246 5.7E-53 T 28-03-2018 hmeg3_RS11680 2085569335b8b6a17cf5eb7e04f5a201 288 Gene3D G3DSA:3.40.630.30 55 263 1.5E-25 T 28-03-2018 hmeg3_RS11680 2085569335b8b6a17cf5eb7e04f5a201 288 SMART SM01006 98 145 3.1E-18 T 28-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain hmeg3_RS04685 414cfdea7df4a6d9f89427a977690373 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 227 2.2E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04685 414cfdea7df4a6d9f89427a977690373 231 Gene3D G3DSA:1.10.3720.10 1 222 8.4E-39 T 28-03-2018 hmeg3_RS04685 414cfdea7df4a6d9f89427a977690373 231 SUPERFAMILY SSF161098 18 213 6.54E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04685 414cfdea7df4a6d9f89427a977690373 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 121 3.3E-25 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 Gene3D G3DSA:3.40.50.1240 1 248 8.3E-67 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 PIRSF PIRSF000709 145 239 0.32 T 28-03-2018 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 PIRSF PIRSF000709 2 111 3.6E-8 T 28-03-2018 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.081 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 141 220 9.5E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 124 2.9E-29 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 SUPERFAMILY SSF53254 1 245 2.09E-79 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 SMART SM00855 3 189 5.9E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS22580 730025905c20c928adf86eb0389ca858 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 246 2.6E-117 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 hmeg3_RS23105 9c64ff685a8e0fd149befe9040658127 333 Pfam PF13379 NMT1-like family 23 266 2.7E-39 T 28-03-2018 hmeg3_RS23105 9c64ff685a8e0fd149befe9040658127 333 Gene3D G3DSA:3.40.190.10 22 141 9.1E-12 T 28-03-2018 hmeg3_RS23105 9c64ff685a8e0fd149befe9040658127 333 Gene3D G3DSA:3.40.190.10 144 330 3.4E-16 T 28-03-2018 hmeg3_RS23105 9c64ff685a8e0fd149befe9040658127 333 SUPERFAMILY SSF53850 27 265 1.98E-31 T 28-03-2018 hmeg3_RS23885 2a7f12a1e563b6aabaf430dd047a894f 246 Gene3D G3DSA:3.40.50.1000 5 222 1.2E-20 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS23885 2a7f12a1e563b6aabaf430dd047a894f 246 SUPERFAMILY SSF56784 13 235 6.32E-36 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS23885 2a7f12a1e563b6aabaf430dd047a894f 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 205 1.2E-11 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04370 c73048eb07643080deb29829f5824516 312 Pfam PF02535 ZIP Zinc transporter 167 307 4.1E-17 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 hmeg3_RS21325 6167677016a9b04127c23b8a8bcaa993 258 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 47 243 5.1E-35 T 28-03-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 hmeg3_RS21325 6167677016a9b04127c23b8a8bcaa993 258 SUPERFAMILY SSF110710 4 250 2.88E-49 T 28-03-2018 hmeg3_RS20725 7203ee7d1126331af0456ed3025f1d2f 366 Gene3D G3DSA:3.40.50.2300 153 366 1.6E-51 T 28-03-2018 hmeg3_RS20725 7203ee7d1126331af0456ed3025f1d2f 366 Gene3D G3DSA:3.40.50.2300 35 152 8.0E-30 T 28-03-2018 hmeg3_RS20725 7203ee7d1126331af0456ed3025f1d2f 366 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 320 1.0E-54 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 hmeg3_RS18740 db0efc46e5fab66f7e7176687ad9c4ac 500 Pfam PF00474 Sodium:solute symporter family 48 435 1.4E-21 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS17220 5ae565a21a5e348ddc5fc0aa728cb633 220 Gene3D G3DSA:3.20.20.70 4 219 6.8E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS17220 5ae565a21a5e348ddc5fc0aa728cb633 220 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 5 217 40.161 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 hmeg3_RS17220 5ae565a21a5e348ddc5fc0aa728cb633 220 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 7 212 9.4E-46 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 hmeg3_RS17220 5ae565a21a5e348ddc5fc0aa728cb633 220 SUPERFAMILY SSF51366 5 215 1.88E-57 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 hmeg3_RS23205 94a507a59912181679fc0ccb596f6904 258 Gene3D G3DSA:3.40.50.360 1 258 3.5E-65 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS23205 94a507a59912181679fc0ccb596f6904 258 SUPERFAMILY SSF52218 1 254 1.48E-71 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS23205 94a507a59912181679fc0ccb596f6904 258 Pfam PF02525 Flavodoxin-like fold 1 215 3.9E-54 T 28-03-2018 IPR003680 Flavodoxin-like fold hmeg3_RS01585 5b3deab3c3af441d931325e53cfd238c 162 Gene3D G3DSA:3.30.1330.40 7 160 3.4E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS01585 5b3deab3c3af441d931325e53cfd238c 162 SUPERFAMILY SSF55298 12 159 4.24E-45 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS01585 5b3deab3c3af441d931325e53cfd238c 162 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 13 157 1.5E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS11585 20d30e98edb5033acd714b21ba93d4ce 68 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 4.5E-15 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type hmeg3_RS11585 20d30e98edb5033acd714b21ba93d4ce 68 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 46 9.2E-9 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type hmeg3_RS23215 756df4db8153b0a2a17c6fad0d5ae388 275 Pfam PF00892 EamA-like transporter family 144 274 3.4E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS23215 756df4db8153b0a2a17c6fad0d5ae388 275 SUPERFAMILY SSF103481 175 274 3.92E-12 T 28-03-2018 hmeg3_RS23215 756df4db8153b0a2a17c6fad0d5ae388 275 SUPERFAMILY SSF103481 36 135 1.23E-11 T 28-03-2018 hmeg3_RS12810 bc0a4c2072f051cfc9ad6e7b28b549b9 125 PIRSF PIRSF029720 2 125 5.0E-41 T 28-03-2018 IPR014558 Uncharacterised conserved lipoprotein hmeg3_RS12810 bc0a4c2072f051cfc9ad6e7b28b549b9 125 Pfam PF03640 Secreted repeat of unknown function 36 71 8.0E-12 T 28-03-2018 IPR005297 Lipoprotein repeat hmeg3_RS12810 bc0a4c2072f051cfc9ad6e7b28b549b9 125 Pfam PF03640 Secreted repeat of unknown function 81 124 6.0E-18 T 28-03-2018 IPR005297 Lipoprotein repeat hmeg3_RS20925 6294afa3445a76cc94ce7b300f843ca4 316 Gene3D G3DSA:3.10.129.10 162 297 2.8E-23 T 28-03-2018 hmeg3_RS20925 6294afa3445a76cc94ce7b300f843ca4 316 Pfam PF01575 MaoC like domain 170 267 3.9E-25 T 28-03-2018 IPR002539 MaoC-like domain hmeg3_RS20925 6294afa3445a76cc94ce7b300f843ca4 316 Pfam PF13452 N-terminal half of MaoC dehydratase 20 137 1.0E-10 T 28-03-2018 hmeg3_RS20925 6294afa3445a76cc94ce7b300f843ca4 316 Gene3D G3DSA:3.10.129.10 15 161 2.8E-37 T 28-03-2018 hmeg3_RS20925 6294afa3445a76cc94ce7b300f843ca4 316 SUPERFAMILY SSF54637 169 285 4.33E-28 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS20925 6294afa3445a76cc94ce7b300f843ca4 316 SUPERFAMILY SSF54637 11 158 6.13E-43 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS24050 d999fcd2599def9ebdb4c4d1b61db503 356 Gene3D G3DSA:2.120.10.30 47 355 1.3E-40 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like hmeg3_RS24050 d999fcd2599def9ebdb4c4d1b61db503 356 SUPERFAMILY SSF63829 44 354 3.92E-67 T 28-03-2018 hmeg3_RS24050 d999fcd2599def9ebdb4c4d1b61db503 356 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 273 290 9.1E-5 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS24050 d999fcd2599def9ebdb4c4d1b61db503 356 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 78 95 9.1E-5 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS24050 d999fcd2599def9ebdb4c4d1b61db503 356 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 208 230 9.1E-5 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS24050 d999fcd2599def9ebdb4c4d1b61db503 356 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 77 343 8.7E-62 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 SUPERFAMILY SSF49785 374 614 6.38E-57 T 28-03-2018 IPR008979 Galactose-binding domain-like hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 SUPERFAMILY SSF53474 2 377 3.64E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 13 297 1.2E-52 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 Gene3D G3DSA:3.40.50.1820 1 373 1.9E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 342 608 2.9E-53 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 Gene3D G3DSA:2.60.120.260 374 613 3.2E-58 T 28-03-2018 IPR008979 Galactose-binding domain-like hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 9 614 3.5E-108 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 hmeg3_RS09560 a9bf2d52f45af62c40787483f1c6b98d 620 SMART SM00939 327 609 1.1E-78 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 hmeg3_RS21455 90d80ccc8fdd02609a52a57e6f7c1bec 139 Pfam PF11191 Protein of unknown function (DUF2782) 33 121 7.2E-8 T 28-03-2018 IPR021357 Protein of unknown function DUF2782 hmeg3_RS16515 f335e8d279fc987eb1fe9075a613f0e5 382 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 372 2.8E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16515 f335e8d279fc987eb1fe9075a613f0e5 382 Gene3D G3DSA:1.10.3470.10 38 377 4.5E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS19405 77af61abfc3bb0b57c0ba9dc8655f3df 362 Pfam PF14350 Beta protein 5 347 4.5E-70 T 28-03-2018 IPR025683 Protein beta hmeg3_RS13295 a0cfa738756b1991f4c0a13e4e28872c 450 Pfam PF11902 Protein of unknown function (DUF3422) 9 446 5.6E-154 T 28-03-2018 IPR021830 Protein of unknown function DUF3422 hmeg3_RS07815 519de7c5e37af9387d4a9a96de66431b 411 Pfam PF13480 Acetyltransferase (GNAT) domain 193 337 2.5E-33 T 28-03-2018 hmeg3_RS07815 519de7c5e37af9387d4a9a96de66431b 411 SUPERFAMILY SSF55729 193 347 1.13E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS07815 519de7c5e37af9387d4a9a96de66431b 411 Gene3D G3DSA:3.40.630.30 152 390 1.8E-17 T 28-03-2018 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 453 2.3E-107 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 SUPERFAMILY SSF50156 206 296 7.49E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 Gene3D G3DSA:2.30.42.10 200 307 1.8E-15 T 28-03-2018 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 Pfam PF02163 Peptidase family M50 9 440 8.9E-81 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 Gene3D G3DSA:2.30.42.10 28 192 7.4E-7 T 28-03-2018 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 Pfam PF13180 PDZ domain 238 293 2.7E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 SMART SM00228 118 190 5.4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 SMART SM00228 220 286 2.5E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS09970 dca4ef37b09df3caf49aeb051f1adfb5 454 SUPERFAMILY SSF50156 92 188 9.99E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 hmeg3_RS18555 42ff23c4b45f9fef8290289a5581a530 390 SUPERFAMILY SSF103473 5 378 6.8E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS18555 42ff23c4b45f9fef8290289a5581a530 390 Pfam PF07690 Major Facilitator Superfamily 15 350 6.5E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS18555 42ff23c4b45f9fef8290289a5581a530 390 Gene3D G3DSA:1.20.1250.20 199 389 2.5E-10 T 28-03-2018 hmeg3_RS18555 42ff23c4b45f9fef8290289a5581a530 390 Gene3D G3DSA:1.20.1250.20 5 193 8.7E-26 T 28-03-2018 hmeg3_RS14100 036e4f0c034f99181facfa90d1c0538e 301 SUPERFAMILY SSF103481 39 141 8.11E-15 T 28-03-2018 hmeg3_RS14100 036e4f0c034f99181facfa90d1c0538e 301 Pfam PF00892 EamA-like transporter family 153 286 8.2E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS14100 036e4f0c034f99181facfa90d1c0538e 301 Pfam PF00892 EamA-like transporter family 6 138 6.2E-23 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS14100 036e4f0c034f99181facfa90d1c0538e 301 SUPERFAMILY SSF103481 188 288 1.96E-10 T 28-03-2018 hmeg3_RS01665 3c9b37dad73cdfb1597d6e4c5ebf1724 156 SUPERFAMILY SSF51182 75 148 4.45E-17 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS01665 3c9b37dad73cdfb1597d6e4c5ebf1724 156 Gene3D G3DSA:2.60.120.10 65 154 2.2E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS01665 3c9b37dad73cdfb1597d6e4c5ebf1724 156 Pfam PF07883 Cupin domain 84 142 5.1E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS24495 88b739b0809c7fb35831b71d853027af 189 SUPERFAMILY SSF69118 3 177 9.95E-26 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS24495 88b739b0809c7fb35831b71d853027af 189 Gene3D G3DSA:1.20.1290.10 16 181 3.2E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS24495 88b739b0809c7fb35831b71d853027af 189 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 107 1.2E-4 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS08275 e6f75edf11671399d476426e82f9a06e 161 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 61 129 1.3E-20 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 hmeg3_RS08275 e6f75edf11671399d476426e82f9a06e 161 Pfam PF04347 Flagellar biosynthesis protein, FliO 73 153 2.0E-19 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 hmeg3_RS12650 62c481fa1eae6301a27a79a1da7ed9c8 148 SUPERFAMILY SSF52172 2 135 8.4E-32 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS12650 62c481fa1eae6301a27a79a1da7ed9c8 148 Gene3D G3DSA:3.40.50.2300 2 138 1.8E-28 T 28-03-2018 hmeg3_RS12650 62c481fa1eae6301a27a79a1da7ed9c8 148 SMART SM00448 7 132 5.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS12650 62c481fa1eae6301a27a79a1da7ed9c8 148 Pfam PF00072 Response regulator receiver domain 9 132 1.1E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS03460 cf224ac38c16807b1dcadc6b4fbc198a 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 171 190 3.0E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS03460 cf224ac38c16807b1dcadc6b4fbc198a 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 3.0E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS03460 cf224ac38c16807b1dcadc6b4fbc198a 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 53 75 3.0E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS03460 cf224ac38c16807b1dcadc6b4fbc198a 254 PIRSF PIRSF006648 4 248 1.3E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 hmeg3_RS03460 cf224ac38c16807b1dcadc6b4fbc198a 254 Pfam PF01061 ABC-2 type transporter 4 214 1.3E-36 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 hmeg3_RS03460 cf224ac38c16807b1dcadc6b4fbc198a 254 Gene3D G3DSA:1.10.357.20 13 167 3.3E-5 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 hmeg3_RS20775 f39c5508517b5824bc1dc24507e92c0b 70 Gene3D G3DSA:1.20.5.1230 3 70 9.0E-6 T 28-03-2018 hmeg3_RS00870 20119b8bd315bd61180d66e9eb71df21 231 Gene3D G3DSA:3.40.1080.10 1 231 3.8E-96 T 28-03-2018 hmeg3_RS00870 20119b8bd315bd61180d66e9eb71df21 231 SUPERFAMILY SSF100950 2 226 2.69E-86 T 28-03-2018 hmeg3_RS00870 20119b8bd315bd61180d66e9eb71df21 231 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00870 20119b8bd315bd61180d66e9eb71df21 231 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 216 4.1E-80 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00870 20119b8bd315bd61180d66e9eb71df21 231 Pfam PF01144 Coenzyme A transferase 8 217 4.9E-79 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00870 20119b8bd315bd61180d66e9eb71df21 231 SMART SM00882 5 217 1.1E-89 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 hmeg3_RS00395 478e5ff93dc98ea780abea967a17b67b 182 Pfam PF06778 Chlorite dismutase 45 177 1.1E-9 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase hmeg3_RS00395 478e5ff93dc98ea780abea967a17b67b 182 SUPERFAMILY SSF54909 44 178 1.85E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS00395 478e5ff93dc98ea780abea967a17b67b 182 Gene3D G3DSA:3.30.70.1100 83 182 2.5E-19 T 28-03-2018 hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 Gene3D G3DSA:3.20.20.100 9 288 9.6E-67 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 PRINTS PR00069 Aldo-keto reductase signature 52 76 3.4E-12 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 PRINTS PR00069 Aldo-keto reductase signature 117 135 3.4E-12 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 PRINTS PR00069 Aldo-keto reductase signature 152 169 3.4E-12 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 PRINTS PR00069 Aldo-keto reductase signature 222 246 3.4E-12 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 SUPERFAMILY SSF51430 17 288 3.01E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS12080 260e1b7d8ae7f8bab339bf5f27f94c60 288 Pfam PF00248 Aldo/keto reductase family 22 288 3.5E-51 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 547 1.1E-158 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 SUPERFAMILY SSF52540 1 198 1.75E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 SUPERFAMILY SSF52540 348 508 1.75E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 SUPERFAMILY SSF52540 285 320 1.75E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 506 9.1E-19 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 Gene3D G3DSA:3.40.50.300 1 528 5.4E-48 T 28-03-2018 hmeg3_RS20400 356070949f30061646374c64a6b8df8c 548 PIRSF PIRSF003128 1 548 3.5E-158 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 hmeg3_RS01480 03977eaba8b952c019186fde734f386e 229 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 229 9.8E-99 T 28-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE hmeg3_RS01480 03977eaba8b952c019186fde734f386e 229 Gene3D G3DSA:3.40.50.300 1 228 6.1E-54 T 28-03-2018 hmeg3_RS01480 03977eaba8b952c019186fde734f386e 229 SUPERFAMILY SSF52540 3 218 1.02E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01480 03977eaba8b952c019186fde734f386e 229 SMART SM00382 26 208 1.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01480 03977eaba8b952c019186fde734f386e 229 Pfam PF00005 ABC transporter 18 158 2.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS07205 43ea35f76cb2143c6a86333f2f75029e 711 SUPERFAMILY SSF56935 26 710 4.33E-134 T 28-03-2018 hmeg3_RS07205 43ea35f76cb2143c6a86333f2f75029e 711 Gene3D G3DSA:2.40.170.20 169 710 1.9E-83 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07205 43ea35f76cb2143c6a86333f2f75029e 711 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 63 709 1.5E-96 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 hmeg3_RS07205 43ea35f76cb2143c6a86333f2f75029e 711 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 156 1.2E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07205 43ea35f76cb2143c6a86333f2f75029e 711 Gene3D G3DSA:2.170.130.10 25 164 5.6E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 hmeg3_RS07205 43ea35f76cb2143c6a86333f2f75029e 711 Pfam PF00593 TonB dependent receptor 239 710 1.1E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 hmeg3_RS02815 22e97538aa18620a96ff43e00775a699 272 Gene3D G3DSA:3.30.70.1070 193 270 0.007 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS02815 22e97538aa18620a96ff43e00775a699 272 Gene3D G3DSA:3.30.70.1070 123 192 0.028 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS02815 22e97538aa18620a96ff43e00775a699 272 SUPERFAMILY SSF110997 130 189 4.84E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS21615 c41345d67fdc089de761eb6bb5747240 151 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 145 1.1E-48 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 hmeg3_RS21615 c41345d67fdc089de761eb6bb5747240 151 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.861 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 SUPERFAMILY SSF46689 3 59 7.98E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 Gene3D G3DSA:1.10.10.60 1 44 3.1E-19 T 28-03-2018 hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 Gene3D G3DSA:1.10.10.60 45 153 3.2E-10 T 28-03-2018 hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS00690 bcbb42039aff29adfc661bd326f3785f 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 hmeg3_RS20770 ce63e83788c9cb8d5b4794e65b94fb1f 524 Gene3D G3DSA:3.30.70.360 251 426 1.3E-39 T 28-03-2018 hmeg3_RS20770 ce63e83788c9cb8d5b4794e65b94fb1f 524 Pfam PF07687 Peptidase dimerisation domain 245 398 5.9E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS20770 ce63e83788c9cb8d5b4794e65b94fb1f 524 Gene3D G3DSA:3.40.630.10 36 250 2.7E-25 T 28-03-2018 hmeg3_RS20770 ce63e83788c9cb8d5b4794e65b94fb1f 524 Pfam PF01546 Peptidase family M20/M25/M40 110 515 1.8E-18 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS20770 ce63e83788c9cb8d5b4794e65b94fb1f 524 SUPERFAMILY SSF53187 432 516 4.1E-42 T 28-03-2018 hmeg3_RS20770 ce63e83788c9cb8d5b4794e65b94fb1f 524 SUPERFAMILY SSF53187 46 247 4.1E-42 T 28-03-2018 hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 176 4.6E-32 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 4.6E-32 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 244 262 4.6E-32 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 17 34 4.6E-32 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 133 155 4.6E-32 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 202 219 4.6E-32 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 SUPERFAMILY SSF63829 11 294 1.08E-63 T 28-03-2018 hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 16 262 1.3E-75 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region hmeg3_RS04515 8262f24c07eca6d12a724ba34a2db064 297 Gene3D G3DSA:2.120.10.30 1 297 1.9E-30 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like hmeg3_RS22680 91463db27de159d12045f6c0094be5e0 403 Gene3D G3DSA:3.40.50.2300 15 167 4.4E-21 T 28-03-2018 hmeg3_RS22680 91463db27de159d12045f6c0094be5e0 403 Pfam PF13458 Periplasmic binding protein 31 367 3.6E-83 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS22680 91463db27de159d12045f6c0094be5e0 403 SUPERFAMILY SSF53822 31 402 6.73E-88 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS22680 91463db27de159d12045f6c0094be5e0 403 Gene3D G3DSA:3.40.50.2300 168 344 1.2E-28 T 28-03-2018 hmeg3_RS06020 37941dcd116dd9225ed94dd190bccee5 127 Gene3D G3DSA:3.10.450.50 2 127 6.8E-21 T 28-03-2018 hmeg3_RS06020 37941dcd116dd9225ed94dd190bccee5 127 SUPERFAMILY SSF54427 3 126 6.1E-36 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS06020 37941dcd116dd9225ed94dd190bccee5 127 Pfam PF11533 Protein of unknown function (DUF3225) 4 126 6.2E-60 T 28-03-2018 IPR024507 Protein of unknown function DUF3225 hmeg3_RS02570 1ca0f28a256161fdc44630738e17cca4 421 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 420 37.358 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 hmeg3_RS02570 1ca0f28a256161fdc44630738e17cca4 421 Pfam PF04285 Protein of unknown function (DUF444) 4 418 8.0E-180 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 hmeg3_RS02570 1ca0f28a256161fdc44630738e17cca4 421 Gene3D G3DSA:3.40.50.410 230 363 0.0018 T 28-03-2018 IPR002035 von Willebrand factor, type A hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 204 222 1.1E-32 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 23 37 1.1E-32 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 227 247 1.1E-32 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 185 202 1.1E-32 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 58 78 1.1E-32 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 Pfam PF01555 DNA methylase 24 243 1.2E-52 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 Gene3D G3DSA:3.40.50.150 5 262 3.8E-65 T 28-03-2018 hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 SUPERFAMILY SSF53335 2 249 6.67E-71 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS03485 1e7d290cfc21bd1109e313a4733e6e0b 263 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 27 33 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 hmeg3_RS08040 4fc3060e3fbb0c095ad03677dd923e76 267 Pfam PF01925 Sulfite exporter TauE/SafE 11 262 5.4E-54 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 SMART SM00304 211 263 3.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 Gene3D G3DSA:1.10.287.950 32 317 2.4E-15 T 28-03-2018 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 Gene3D G3DSA:1.10.287.950 318 513 9.5E-48 T 28-03-2018 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 Pfam PF00672 HAMP domain 212 259 1.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 SUPERFAMILY SSF58104 231 512 3.27E-72 T 28-03-2018 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 SMART SM00283 264 511 6.4E-91 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 168 1.0E-18 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS03715 4c42709a1815d9b905542ef9e88aea75 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 479 1.7E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 SUPERFAMILY SSF56436 182 403 3.96E-61 T 28-03-2018 IPR016187 C-type lectin fold hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 Gene3D G3DSA:3.90.1580.10 329 404 4.7E-10 T 28-03-2018 hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 Gene3D G3DSA:3.90.1580.10 172 328 5.0E-36 T 28-03-2018 hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 Pfam PF03781 Sulfatase-modifying factor enzyme 1 189 320 7.1E-20 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 Gene3D G3DSA:1.20.120.450 2 150 3.7E-7 T 28-03-2018 hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 16 401 3.7E-148 T 28-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 hmeg3_RS06950 2660ecab7dc181b70af5989f874f7627 404 Pfam PF12867 DinB superfamily 21 152 4.4E-11 T 28-03-2018 IPR024775 DinB-like domain hmeg3_RS17195 3acae60ff3a3a3e962db12f6d1c5b3fa 343 Pfam PF05036 Sporulation related domain 268 341 7.8E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS17195 3acae60ff3a3a3e962db12f6d1c5b3fa 343 SUPERFAMILY SSF110997 267 341 5.23E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS17195 3acae60ff3a3a3e962db12f6d1c5b3fa 343 Gene3D G3DSA:3.30.70.1070 269 343 1.7E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 hmeg3_RS21220 a6b170042eb96921a35bdd82dae53242 200 SUPERFAMILY SSF53335 44 139 8.75E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS21220 a6b170042eb96921a35bdd82dae53242 200 Gene3D G3DSA:3.40.50.150 17 200 4.8E-7 T 28-03-2018 hmeg3_RS21220 a6b170042eb96921a35bdd82dae53242 200 Pfam PF03269 Caenorhabditis protein of unknown function, DUF268 92 166 1.4E-15 T 28-03-2018 IPR004951 Protein of unknown function DUF268, Caenorhabditis species hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 Pfam PF00005 ABC transporter 61 211 3.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 Gene3D G3DSA:3.40.50.300 17 351 6.2E-77 T 28-03-2018 hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 SMART SM00382 69 261 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 263 327 3.8E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 SUPERFAMILY SSF52540 54 283 7.26E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS04600 82b5d3f13315b2eccc4b17c6c886c3bc 351 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 261 347 3.4E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 hmeg3_RS03100 d0a452ec611da223faf61129aab9a9f8 334 Pfam PF06189 5'-nucleotidase 39 296 1.8E-108 T 28-03-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 hmeg3_RS03100 d0a452ec611da223faf61129aab9a9f8 334 Gene3D G3DSA:3.40.50.1000 15 152 0.011 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS03100 d0a452ec611da223faf61129aab9a9f8 334 Gene3D G3DSA:3.40.50.1000 155 289 3.7E-18 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS23015 571498d3442fdc134406c7d2ec08c6c1 261 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 27 261 9.3E-43 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 hmeg3_RS23015 571498d3442fdc134406c7d2ec08c6c1 261 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 261 3.2E-46 T 28-03-2018 IPR010239 Conserved hypothetical protein CHP02001 hmeg3_RS09645 e39e8a1c3139c2edb8427e9f94278f42 340 Gene3D G3DSA:3.40.1350.10 2 137 3.1E-10 T 28-03-2018 hmeg3_RS09645 e39e8a1c3139c2edb8427e9f94278f42 340 SUPERFAMILY SSF52980 8 123 6.17E-7 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 hmeg3_RS09645 e39e8a1c3139c2edb8427e9f94278f42 340 Gene3D G3DSA:3.40.1350.10 178 319 0.059 T 28-03-2018 hmeg3_RS09645 e39e8a1c3139c2edb8427e9f94278f42 340 Pfam PF04471 Restriction endonuclease 7 122 7.7E-7 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 hmeg3_RS03325 241794ca653492c5a1705c125f6245af 378 Pfam PF02628 Cytochrome oxidase assembly protein 31 346 9.4E-86 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 hmeg3_RS00090 aba3c831481866041b06c40a1e90b4c6 261 SMART SM00382 34 215 2.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS00090 aba3c831481866041b06c40a1e90b4c6 261 Gene3D G3DSA:3.40.50.300 2 233 8.3E-57 T 28-03-2018 hmeg3_RS00090 aba3c831481866041b06c40a1e90b4c6 261 SUPERFAMILY SSF52540 4 230 1.32E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS00090 aba3c831481866041b06c40a1e90b4c6 261 Pfam PF00005 ABC transporter 26 164 4.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS00090 aba3c831481866041b06c40a1e90b4c6 261 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS02670 ec5bb4eaf0d64a9992875616eb8050bf 290 Pfam PF00756 Putative esterase 39 279 6.1E-31 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 hmeg3_RS02670 ec5bb4eaf0d64a9992875616eb8050bf 290 SUPERFAMILY SSF53474 22 283 6.81E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02670 ec5bb4eaf0d64a9992875616eb8050bf 290 Gene3D G3DSA:3.40.50.1820 21 290 2.2E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS05945 1d8f1df03b9717249b0ab523f5603d31 416 SUPERFAMILY SSF103473 17 413 3.66E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS05945 1d8f1df03b9717249b0ab523f5603d31 416 Gene3D G3DSA:1.20.1250.20 222 414 3.4E-19 T 28-03-2018 hmeg3_RS05945 1d8f1df03b9717249b0ab523f5603d31 416 Pfam PF07690 Major Facilitator Superfamily 32 380 2.3E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS05945 1d8f1df03b9717249b0ab523f5603d31 416 Gene3D G3DSA:1.20.1250.20 16 221 5.7E-29 T 28-03-2018 hmeg3_RS21190 25b52263b8ab1c42d845027198369882 277 SUPERFAMILY SSF53448 30 199 1.41E-10 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS21190 25b52263b8ab1c42d845027198369882 277 Gene3D G3DSA:3.90.550.10 1 266 8.1E-11 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 Gene3D G3DSA:3.40.50.1820 13 329 1.1E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 24 326 1.1E-135 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 Pfam PF00561 alpha/beta hydrolase fold 50 309 1.0E-32 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PIRSF PIRSF006431 14 329 1.2E-141 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 SUPERFAMILY SSF53474 16 310 6.95E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 78 89 3.3E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 121 135 3.3E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 52 60 3.3E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 75 90 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12120 f6f754499415e0ec72465614d33f3e31 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS21925 442945c68d943121220d82f0c0db4318 251 SUPERFAMILY SSF160950 2 249 2.75E-87 T 28-03-2018 IPR009777 Cell division protein ZapD hmeg3_RS21925 442945c68d943121220d82f0c0db4318 251 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 249 32.53 T 28-03-2018 IPR009777 Cell division protein ZapD hmeg3_RS21925 442945c68d943121220d82f0c0db4318 251 Gene3D G3DSA:2.60.440.10 173 249 2.3E-26 T 28-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain hmeg3_RS21925 442945c68d943121220d82f0c0db4318 251 Pfam PF07072 Cell division protein 16 225 1.9E-78 T 28-03-2018 IPR009777 Cell division protein ZapD hmeg3_RS21925 442945c68d943121220d82f0c0db4318 251 Gene3D G3DSA:1.10.3900.10 10 172 4.5E-62 T 28-03-2018 hmeg3_RS09810 faa2e84d880741da94b9620692821444 195 Pfam PF06366 Flagellar protein FlhE 105 191 7.3E-20 T 28-03-2018 IPR009420 Flagellar protein FlhE hmeg3_RS11160 af1f7817a5e7e884a8329d3d2da5e1d6 71 Pfam PF11174 Protein of unknown function (DUF2970) 14 69 3.6E-20 T 28-03-2018 IPR021344 Protein of unknown function DUF2970 hmeg3_RS03310 c9d6ad0bbb778bdd62e63d6429184bdf 66 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 2.3E-24 T 28-03-2018 IPR021313 Protein of unknown function DUF2909 hmeg3_RS03275 f557e7f69500cfedb4dd5192be5a398d 311 Gene3D G3DSA:3.40.50.150 45 300 2.6E-35 T 28-03-2018 hmeg3_RS03275 f557e7f69500cfedb4dd5192be5a398d 311 Pfam PF08241 Methyltransferase domain 60 174 2.3E-18 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 hmeg3_RS03275 f557e7f69500cfedb4dd5192be5a398d 311 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 16 291 26.853 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 hmeg3_RS03275 f557e7f69500cfedb4dd5192be5a398d 311 SUPERFAMILY SSF53335 34 286 2.79E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS11465 6648f900198f6f330668c80b0660ba6b 151 Gene3D G3DSA:3.40.50.620 2 150 6.7E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS11465 6648f900198f6f330668c80b0660ba6b 151 SUPERFAMILY SSF52402 1 147 8.04E-37 T 28-03-2018 hmeg3_RS11465 6648f900198f6f330668c80b0660ba6b 151 PRINTS PR01438 Universal stress protein signature 124 146 8.8E-20 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11465 6648f900198f6f330668c80b0660ba6b 151 PRINTS PR01438 Universal stress protein signature 2 20 8.8E-20 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11465 6648f900198f6f330668c80b0660ba6b 151 PRINTS PR01438 Universal stress protein signature 106 118 8.8E-20 T 28-03-2018 IPR006015 Universal stress protein A hmeg3_RS11465 6648f900198f6f330668c80b0660ba6b 151 Pfam PF00582 Universal stress protein family 1 146 4.5E-32 T 28-03-2018 IPR006016 UspA GO:0006950 hmeg3_RS14055 ab0840bb839901f7bfd3819a2bfdbba7 159 Gene3D G3DSA:3.40.630.30 11 146 3.9E-22 T 28-03-2018 hmeg3_RS14055 ab0840bb839901f7bfd3819a2bfdbba7 159 Pfam PF00583 Acetyltransferase (GNAT) family 46 140 6.9E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS14055 ab0840bb839901f7bfd3819a2bfdbba7 159 SUPERFAMILY SSF55729 36 141 3.82E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 Gene3D G3DSA:1.10.580.10 57 306 6.4E-90 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 427 2.8E-242 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 ProSitePatterns PS00480 Citrate synthase signature. 307 319 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 SUPERFAMILY SSF48256 10 433 1.28E-165 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PRINTS PR00143 Citrate synthase signature 364 380 5.2E-55 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PRINTS PR00143 Citrate synthase signature 169 182 5.2E-55 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PRINTS PR00143 Citrate synthase signature 223 238 5.2E-55 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PRINTS PR00143 Citrate synthase signature 245 273 5.2E-55 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PRINTS PR00143 Citrate synthase signature 300 320 5.2E-55 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PRINTS PR00143 Citrate synthase signature 384 398 5.2E-55 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 Pfam PF00285 Citrate synthase, C-terminal domain 50 416 3.1E-133 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 Gene3D G3DSA:1.10.580.10 345 409 9.9E-8 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain hmeg3_RS08775 9aa57331d4ac2d7041f6ab021308b259 433 PIRSF PIRSF001369 41 433 3.9E-166 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type hmeg3_RS07460 a36af2c283e68310aedb7db07c3f0738 421 Pfam PF01076 Plasmid recombination enzyme 13 191 1.6E-19 T 28-03-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 hmeg3_RS16070 0a2507cb774eb7f17ea4a6721f8c3f0d 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 hmeg3_RS16070 0a2507cb774eb7f17ea4a6721f8c3f0d 315 Gene3D G3DSA:3.40.1190.20 6 314 4.0E-62 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS16070 0a2507cb774eb7f17ea4a6721f8c3f0d 315 SUPERFAMILY SSF53613 5 312 4.05E-80 T 28-03-2018 IPR029056 Ribokinase-like hmeg3_RS16070 0a2507cb774eb7f17ea4a6721f8c3f0d 315 Pfam PF00294 pfkB family carbohydrate kinase 7 306 1.1E-55 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 SUPERFAMILY SSF53901 207 395 6.26E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 239 339 2.9E-27 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 50 231 2.6E-21 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 SMART SM00825 Beta-ketoacyl synthase 9 396 1.3E-7 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 Gene3D G3DSA:3.40.47.10 244 396 7.6E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 SUPERFAMILY SSF53901 3 233 8.23E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS16245 fb0f660915ba5e82775cb421a72ece78 396 Gene3D G3DSA:3.40.47.10 2 238 2.9E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 hmeg3_RS05980 09ee8ae5a0e851951854fae9ae3ce104 338 SUPERFAMILY SSF51679 2 324 5.5E-92 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS05980 09ee8ae5a0e851951854fae9ae3ce104 338 Pfam PF00296 Luciferase-like monooxygenase 5 301 9.2E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 hmeg3_RS05980 09ee8ae5a0e851951854fae9ae3ce104 338 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 325 5.1E-142 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 hmeg3_RS05980 09ee8ae5a0e851951854fae9ae3ce104 338 Gene3D G3DSA:3.20.20.30 8 327 2.2E-78 T 28-03-2018 hmeg3_RS11565 4d62f23382c5553587d74acf4eae0fe7 172 SUPERFAMILY SSF81342 2 171 3.14E-29 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 hmeg3_RS11565 4d62f23382c5553587d74acf4eae0fe7 172 Gene3D G3DSA:1.20.950.20 1 172 1.2E-26 T 28-03-2018 hmeg3_RS11565 4d62f23382c5553587d74acf4eae0fe7 172 Pfam PF01292 Prokaryotic cytochrome b561 4 171 4.6E-22 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 hmeg3_RS20265 b058a5d3e82874ae50c4c0d61fcfa34b 331 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 326 3.8E-105 T 28-03-2018 IPR007296 Domain of unknown function DUF403 hmeg3_RS03125 a9fa646556ce761651f4f61bc1b518dd 443 SUPERFAMILY SSF103473 20 440 3.92E-83 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS03125 a9fa646556ce761651f4f61bc1b518dd 443 Pfam PF07690 Major Facilitator Superfamily 39 402 1.0E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS03125 a9fa646556ce761651f4f61bc1b518dd 443 Gene3D G3DSA:1.20.1250.20 23 234 1.6E-34 T 28-03-2018 hmeg3_RS03125 a9fa646556ce761651f4f61bc1b518dd 443 Gene3D G3DSA:1.20.1250.20 248 443 2.3E-21 T 28-03-2018 hmeg3_RS16570 8ff8fd871ab6c45547719e9c6620f62a 117 Pfam PF12778 PXPV repeat (3 copies) 67 88 4.5E-5 T 28-03-2018 IPR024446 PXPV repeat hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 PRINTS PR01305 Invasion protein B family signature 22 35 1.8E-9 T 28-03-2018 IPR003065 Surface presentation of antigens protein SpaK hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 PRINTS PR01305 Invasion protein B family signature 35 45 1.8E-9 T 28-03-2018 IPR003065 Surface presentation of antigens protein SpaK hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 PRINTS PR01305 Invasion protein B family signature 45 59 1.8E-9 T 28-03-2018 IPR003065 Surface presentation of antigens protein SpaK hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 PRINTS PR01305 Invasion protein B family signature 115 127 1.8E-9 T 28-03-2018 IPR003065 Surface presentation of antigens protein SpaK hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 Pfam PF03519 Invasion protein B family 22 99 4.0E-19 T 28-03-2018 IPR003065 Surface presentation of antigens protein SpaK hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 Gene3D G3DSA:3.30.1460.10 6 136 9.6E-34 T 28-03-2018 hmeg3_RS15825 750a0eea32e043def3e70cb210143995 139 SUPERFAMILY SSF69635 5 137 2.83E-33 T 28-03-2018 hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 Gene3D G3DSA:3.40.640.10 124 363 8.0E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 Gene3D G3DSA:3.90.1150.10 364 456 9.0E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 SUPERFAMILY SSF53383 77 453 1.25E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 SMART SM00345 23 82 4.1E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 Pfam PF00155 Aminotransferase class I and II 113 448 1.8E-19 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 SUPERFAMILY SSF46785 16 90 1.11E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 1.3E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 hmeg3_RS03645 ff2571b81e10d32a75e3a0a78db66b4f 464 Gene3D G3DSA:1.10.10.10 11 84 1.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS19100 2bd73786aef365853fb1000d4dbc7f74 320 SUPERFAMILY SSF161098 79 305 1.23E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19100 2bd73786aef365853fb1000d4dbc7f74 320 Gene3D G3DSA:1.10.3720.10 39 319 1.4E-38 T 28-03-2018 hmeg3_RS19100 2bd73786aef365853fb1000d4dbc7f74 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 304 3.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 SMART SM00862 150 226 6.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 Pfam PF00072 Response regulator receiver domain 4 113 8.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 3.0E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 Gene3D G3DSA:1.10.10.10 122 229 6.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 SMART SM00448 2 112 6.0E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 SUPERFAMILY SSF52172 2 123 2.42E-39 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 SUPERFAMILY SSF46894 132 227 2.72E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 hmeg3_RS10045 6f15095648c7799d56eb29f96fc48734 229 Gene3D G3DSA:3.40.50.2300 1 121 3.1E-35 T 28-03-2018 hmeg3_RS15010 2c0c4d0bf58dcae9e6353f0de8e09a61 317 PIRSF PIRSF035875 11 314 2.7E-66 T 28-03-2018 IPR017039 Virulence factor BrkB hmeg3_RS15010 2c0c4d0bf58dcae9e6353f0de8e09a61 317 Pfam PF03631 Virulence factor BrkB 43 297 2.2E-54 T 28-03-2018 IPR017039 Virulence factor BrkB hmeg3_RS00825 e4e0c80a3ecfc961e793d58a90c9b3dc 397 Gene3D G3DSA:3.40.50.2300 159 337 2.3E-28 T 28-03-2018 hmeg3_RS00825 e4e0c80a3ecfc961e793d58a90c9b3dc 397 Pfam PF13458 Periplasmic binding protein 30 365 4.9E-65 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS00825 e4e0c80a3ecfc961e793d58a90c9b3dc 397 Gene3D G3DSA:3.40.50.2300 23 158 8.6E-13 T 28-03-2018 hmeg3_RS00825 e4e0c80a3ecfc961e793d58a90c9b3dc 397 SUPERFAMILY SSF53822 30 379 2.12E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS13785 ddeb128ea42c88d517a23ab5da20aa99 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 25 118 2.8E-37 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS13785 ddeb128ea42c88d517a23ab5da20aa99 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.011 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 hmeg3_RS18420 5d5c4069a5d4167ab9b656cc6563bae6 128 Pfam PF02566 OsmC-like protein 33 125 4.4E-18 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS18420 5d5c4069a5d4167ab9b656cc6563bae6 128 SUPERFAMILY SSF82784 6 125 1.18E-32 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS18420 5d5c4069a5d4167ab9b656cc6563bae6 128 Gene3D G3DSA:3.30.300.20 1 128 2.1E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS18360 4f526e073466522894bd5e75c6316e28 130 Pfam PF00545 ribonuclease 44 127 2.1E-29 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 hmeg3_RS18360 4f526e073466522894bd5e75c6316e28 130 SUPERFAMILY SSF53933 35 129 8.02E-36 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 hmeg3_RS18360 4f526e073466522894bd5e75c6316e28 130 Gene3D G3DSA:3.10.450.30 34 130 5.5E-34 T 28-03-2018 hmeg3_RS00735 02f68fef3e598b6aec21a57603279926 369 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 21 365 3.7E-125 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 hmeg3_RS00735 02f68fef3e598b6aec21a57603279926 369 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 hmeg3_RS00735 02f68fef3e598b6aec21a57603279926 369 Pfam PF01098 Cell cycle protein 25 365 2.2E-98 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 hmeg3_RS08855 b849618e2a623f71044d2b62ae9be289 393 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 363 72.704 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS08855 b849618e2a623f71044d2b62ae9be289 393 Pfam PF04055 Radical SAM superfamily 108 283 9.2E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 hmeg3_RS08855 b849618e2a623f71044d2b62ae9be289 393 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 366 9.6E-130 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS08855 b849618e2a623f71044d2b62ae9be289 393 PIRSF PIRSF006004 3 376 1.2E-144 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 hmeg3_RS08855 b849618e2a623f71044d2b62ae9be289 393 SUPERFAMILY SSF102114 105 291 5.1E-9 T 28-03-2018 hmeg3_RS08855 b849618e2a623f71044d2b62ae9be289 393 Gene3D G3DSA:3.20.20.70 17 381 2.6E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS15015 fb238fa7ff5bdd2e5d1178d99d7a3022 207 PIRSF PIRSF006707 1 179 1.6E-54 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type hmeg3_RS15015 fb238fa7ff5bdd2e5d1178d99d7a3022 207 SUPERFAMILY SSF46785 6 152 1.22E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15015 fb238fa7ff5bdd2e5d1178d99d7a3022 207 Gene3D G3DSA:1.10.10.10 4 178 6.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS15015 fb238fa7ff5bdd2e5d1178d99d7a3022 207 Pfam PF12802 MarR family 29 84 5.0E-7 T 28-03-2018 hmeg3_RS04715 934f9bd76bda18ef347e4ea11a0da691 130 SUPERFAMILY SSF54211 5 130 1.78E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS04715 934f9bd76bda18ef347e4ea11a0da691 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.94 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid hmeg3_RS04715 934f9bd76bda18ef347e4ea11a0da691 130 Gene3D G3DSA:3.30.230.10 3 130 4.7E-50 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup hmeg3_RS04715 934f9bd76bda18ef347e4ea11a0da691 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 hmeg3_RS04715 934f9bd76bda18ef347e4ea11a0da691 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 8.1E-45 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 hmeg3_RS01780 f34563117d99a4a1e42884f8a6b1349f 127 SUPERFAMILY SSF89082 41 123 5.1E-13 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain hmeg3_RS01780 f34563117d99a4a1e42884f8a6b1349f 127 Pfam PF07739 TipAS antibiotic-recognition domain 23 122 3.8E-17 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain hmeg3_RS01780 f34563117d99a4a1e42884f8a6b1349f 127 Gene3D G3DSA:1.10.490.50 38 125 1.7E-17 T 28-03-2018 hmeg3_RS02785 29ef98f5001d2f688b3a645cae5a9bec 211 SUPERFAMILY SSF53474 3 209 1.88E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02785 29ef98f5001d2f688b3a645cae5a9bec 211 Gene3D G3DSA:3.40.50.1820 1 210 1.0E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02785 29ef98f5001d2f688b3a645cae5a9bec 211 Pfam PF12146 Serine aminopeptidase, S33 54 170 3.1E-9 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS04410 b3362f62980518c8c6bea88545e7af7f 523 Pfam PF03109 ABC1 family 109 227 5.6E-36 T 28-03-2018 IPR004147 UbiB domain hmeg3_RS04410 b3362f62980518c8c6bea88545e7af7f 523 SUPERFAMILY SSF56112 189 433 1.39E-43 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS04410 b3362f62980518c8c6bea88545e7af7f 523 SUPERFAMILY SSF56112 91 154 1.39E-43 T 28-03-2018 IPR011009 Protein kinase-like domain hmeg3_RS04410 b3362f62980518c8c6bea88545e7af7f 523 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 6 439 2.0E-172 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 hmeg3_RS04410 b3362f62980518c8c6bea88545e7af7f 523 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 2 523 50.613 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 hmeg3_RS04410 b3362f62980518c8c6bea88545e7af7f 523 Gene3D G3DSA:3.30.200.20 100 240 5.6E-24 T 28-03-2018 hmeg3_RS16600 d835ef70e42e8eaca99f1a5a90cd0b31 137 SMART SM00448 7 119 3.7E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS16600 d835ef70e42e8eaca99f1a5a90cd0b31 137 SUPERFAMILY SSF52172 7 122 2.28E-25 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS16600 d835ef70e42e8eaca99f1a5a90cd0b31 137 Pfam PF00072 Response regulator receiver domain 9 119 6.2E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS16600 d835ef70e42e8eaca99f1a5a90cd0b31 137 Gene3D G3DSA:3.40.50.2300 1 126 4.0E-26 T 28-03-2018 hmeg3_RS13830 0cf90d9e5d5e150f722196f3276bc4ae 239 Pfam PF06149 Protein of unknown function (DUF969) 7 222 5.5E-84 T 28-03-2018 IPR010374 Protein of unknown function DUF969 hmeg3_RS05250 4395a3d33c6f53bf881e8f976281be4a 235 Gene3D G3DSA:3.40.50.300 1 235 2.8E-56 T 28-03-2018 hmeg3_RS05250 4395a3d33c6f53bf881e8f976281be4a 235 SMART SM00382 26 213 1.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS05250 4395a3d33c6f53bf881e8f976281be4a 235 Pfam PF00005 ABC transporter 17 162 2.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS05250 4395a3d33c6f53bf881e8f976281be4a 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS05250 4395a3d33c6f53bf881e8f976281be4a 235 SUPERFAMILY SSF52540 2 233 5.75E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS14335 7b8fef4f87530cd3935303058282cc89 250 Gene3D G3DSA:1.10.3720.10 1 250 5.0E-45 T 28-03-2018 hmeg3_RS14335 7b8fef4f87530cd3935303058282cc89 250 SUPERFAMILY SSF161098 15 236 3.27E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14335 7b8fef4f87530cd3935303058282cc89 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 244 5.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21525 3462a63214b59f407a2d224c232375ec 413 Gene3D G3DSA:1.20.1250.20 220 412 3.6E-17 T 28-03-2018 hmeg3_RS21525 3462a63214b59f407a2d224c232375ec 413 Gene3D G3DSA:1.20.1250.20 28 217 5.6E-14 T 28-03-2018 hmeg3_RS21525 3462a63214b59f407a2d224c232375ec 413 SUPERFAMILY SSF103473 20 406 1.7E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS21525 3462a63214b59f407a2d224c232375ec 413 Pfam PF07690 Major Facilitator Superfamily 36 291 1.5E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS02365 04cdcdb6bb3d939bcdffece13e18ef9c 170 Gene3D G3DSA:3.40.50.2300 6 147 2.5E-38 T 28-03-2018 hmeg3_RS02365 04cdcdb6bb3d939bcdffece13e18ef9c 170 SMART SM00226 10 148 6.2E-37 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily hmeg3_RS02365 04cdcdb6bb3d939bcdffece13e18ef9c 170 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 12 142 1.1E-19 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily hmeg3_RS02365 04cdcdb6bb3d939bcdffece13e18ef9c 170 SUPERFAMILY SSF52788 10 147 8.77E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily hmeg3_RS24005 9a2fed48f2e83c88fbaf786816d748e1 274 Gene3D G3DSA:3.20.20.60 3 260 5.1E-51 T 28-03-2018 hmeg3_RS24005 9a2fed48f2e83c88fbaf786816d748e1 274 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 247 1.2E-66 T 28-03-2018 hmeg3_RS24005 9a2fed48f2e83c88fbaf786816d748e1 274 SUPERFAMILY SSF51621 3 256 8.9E-60 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 hmeg3_RS12475 4f055f606b0210a1a715f11207690459 425 Pfam PF00999 Sodium/hydrogen exchanger family 8 255 3.3E-22 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 hmeg3_RS17755 90d13156061143ffda3327d8a2429af0 199 Gene3D G3DSA:2.40.160.20 12 199 1.5E-32 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS17755 90d13156061143ffda3327d8a2429af0 199 SUPERFAMILY SSF56925 25 199 3.14E-33 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS17755 90d13156061143ffda3327d8a2429af0 199 Pfam PF01389 OmpA-like transmembrane domain 27 199 3.5E-24 T 28-03-2018 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 hmeg3_RS10925 4ee74cc1a2b8023f948e902ffc8c9465 441 Pfam PF13416 Bacterial extracellular solute-binding protein 67 379 1.7E-34 T 28-03-2018 hmeg3_RS10925 4ee74cc1a2b8023f948e902ffc8c9465 441 SUPERFAMILY SSF53850 45 440 4.51E-50 T 28-03-2018 hmeg3_RS10925 4ee74cc1a2b8023f948e902ffc8c9465 441 Gene3D G3DSA:3.40.190.10 160 364 1.1E-26 T 28-03-2018 hmeg3_RS10925 4ee74cc1a2b8023f948e902ffc8c9465 441 Gene3D G3DSA:3.40.190.10 365 441 0.4 T 28-03-2018 hmeg3_RS01600 e1271cf05a666288c250a145c6dd0e3c 154 Pfam PF00583 Acetyltransferase (GNAT) family 47 133 3.1E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS01600 e1271cf05a666288c250a145c6dd0e3c 154 Gene3D G3DSA:3.40.630.30 2 149 3.0E-27 T 28-03-2018 hmeg3_RS01600 e1271cf05a666288c250a145c6dd0e3c 154 SUPERFAMILY SSF55729 1 141 1.32E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS07625 122084e369e593446b828628d1b5eb43 120 Pfam PF11142 Protein of unknown function (DUF2917) 13 67 9.7E-14 T 28-03-2018 IPR021317 Protein of unknown function DUF2917 hmeg3_RS20425 a32670cd45cb22defaf61c67402f39e7 169 Pfam PF04355 SmpA / OmlA family 62 125 9.9E-23 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 hmeg3_RS20425 a32670cd45cb22defaf61c67402f39e7 169 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 37 138 24.634 T 28-03-2018 IPR026592 Outer membrane protein assembly factor BamE hmeg3_RS20425 a32670cd45cb22defaf61c67402f39e7 169 Gene3D G3DSA:3.30.1450.10 62 130 2.3E-10 T 28-03-2018 hmeg3_RS04465 e79ad624894bdd0239925325fce137ed 124 Pfam PF04379 ApaG domain 16 101 4.5E-36 T 28-03-2018 IPR007474 ApaG domain hmeg3_RS04465 e79ad624894bdd0239925325fce137ed 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 32.483 T 28-03-2018 IPR023065 Uncharacterised protein family ApaG hmeg3_RS04465 e79ad624894bdd0239925325fce137ed 124 SUPERFAMILY SSF110069 3 124 2.49E-50 T 28-03-2018 IPR007474 ApaG domain hmeg3_RS04465 e79ad624894bdd0239925325fce137ed 124 Gene3D G3DSA:2.60.40.1470 1 124 2.7E-46 T 28-03-2018 IPR007474 ApaG domain hmeg3_RS12060 8e2d8bf8df4f991b68adb89e9c406ec7 252 Gene3D G3DSA:3.40.50.1820 13 250 4.1E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12060 8e2d8bf8df4f991b68adb89e9c406ec7 252 SUPERFAMILY SSF53474 24 120 8.28E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12060 8e2d8bf8df4f991b68adb89e9c406ec7 252 SUPERFAMILY SSF53474 149 246 8.28E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12060 8e2d8bf8df4f991b68adb89e9c406ec7 252 Pfam PF12697 Alpha/beta hydrolase family 31 242 4.6E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS18340 e2fcc1e6fbb41dc0a195d1fa0b8d2135 195 Gene3D G3DSA:3.30.870.10 42 195 3.7E-26 T 28-03-2018 hmeg3_RS18340 e2fcc1e6fbb41dc0a195d1fa0b8d2135 195 SUPERFAMILY SSF56024 46 191 9.87E-31 T 28-03-2018 hmeg3_RS18340 e2fcc1e6fbb41dc0a195d1fa0b8d2135 195 Pfam PF13091 PLD-like domain 60 183 1.3E-24 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 PIRSF PIRSF005485 1 343 4.5E-109 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 333 27.608 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 SUPERFAMILY SSF46785 3 84 5.13E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 5 74 2.6E-5 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 SUPERFAMILY SSF55781 72 342 8.83E-61 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 Gene3D G3DSA:3.30.450.40 188 343 2.6E-44 T 28-03-2018 IPR029016 GAF domain-like hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 Pfam PF01628 HrcA protein C terminal domain 107 326 9.8E-58 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 Gene3D G3DSA:1.10.10.10 1 86 3.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20415 00df92af8461da94a3d99c1778208ef5 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 339 1.7E-95 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 hmeg3_RS21885 fea399f683fcd1bebf2698b113c9fa93 103 SUPERFAMILY SSF141091 1 102 5.36E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21885 fea399f683fcd1bebf2698b113c9fa93 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS21885 fea399f683fcd1bebf2698b113c9fa93 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.2E-39 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21885 fea399f683fcd1bebf2698b113c9fa93 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.129 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21885 fea399f683fcd1bebf2698b113c9fa93 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.2E-35 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS20795 8afaffa3efbbf83c9a729d84d5c7721b 301 Pfam PF03466 LysR substrate binding domain 105 291 1.8E-19 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS20795 8afaffa3efbbf83c9a729d84d5c7721b 301 SUPERFAMILY SSF46785 17 126 4.72E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20795 8afaffa3efbbf83c9a729d84d5c7721b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 78 1.2E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS20795 8afaffa3efbbf83c9a729d84d5c7721b 301 SUPERFAMILY SSF53850 104 296 1.09E-26 T 28-03-2018 hmeg3_RS20795 8afaffa3efbbf83c9a729d84d5c7721b 301 Gene3D G3DSA:1.10.10.10 12 99 4.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS20795 8afaffa3efbbf83c9a729d84d5c7721b 301 Gene3D G3DSA:3.40.190.10 103 298 5.4E-19 T 28-03-2018 hmeg3_RS12975 996ea94843c77840f6167a3ee24893b6 82 Gene3D G3DSA:1.10.260.40 2 82 1.5E-15 T 28-03-2018 hmeg3_RS12975 996ea94843c77840f6167a3ee24893b6 82 SUPERFAMILY SSF47413 12 75 1.72E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS12975 996ea94843c77840f6167a3ee24893b6 82 SMART SM00530 16 71 4.2E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS12975 996ea94843c77840f6167a3ee24893b6 82 Pfam PF01381 Helix-turn-helix 17 69 1.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS23515 e5e41f206828defac518d70d9504d742 223 Pfam PF03737 Aldolase/RraA 31 176 3.9E-44 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein hmeg3_RS23515 e5e41f206828defac518d70d9504d742 223 Gene3D G3DSA:3.50.30.40 23 197 2.8E-50 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein hmeg3_RS23515 e5e41f206828defac518d70d9504d742 223 SUPERFAMILY SSF89562 31 184 1.44E-43 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein hmeg3_RS03295 ee5ac0fb9121c61be00f0f440b1be83a 181 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 30 172 1.3E-48 T 28-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03295 ee5ac0fb9121c61be00f0f440b1be83a 181 PIRSF PIRSF005413 1 181 6.9E-63 T 28-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03295 ee5ac0fb9121c61be00f0f440b1be83a 181 Gene3D G3DSA:2.60.370.10 58 176 2.8E-44 T 28-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03295 ee5ac0fb9121c61be00f0f440b1be83a 181 SUPERFAMILY SSF110111 57 174 4.05E-45 T 28-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 Pfam PF01494 FAD binding domain 8 367 3.1E-63 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 Gene3D G3DSA:3.50.50.60 4 411 1.6E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 181 196 6.9E-43 T 28-03-2018 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 6.9E-43 T 28-03-2018 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 6.9E-43 T 28-03-2018 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 6.9E-43 T 28-03-2018 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 6.9E-43 T 28-03-2018 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 6.9E-43 T 28-03-2018 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 SUPERFAMILY SSF51905 288 377 1.15E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16365 86ae8fa46564d50240f9154a8556bbbe 526 SUPERFAMILY SSF51905 7 202 1.15E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS12750 b33be2d8dcd4ea7093b0fd72613094bb 75 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 67 4.2E-26 T 28-03-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 SUPERFAMILY SSF53850 87 299 6.83E-49 T 28-03-2018 hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 Pfam PF03466 LysR substrate binding domain 88 294 1.2E-42 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 SUPERFAMILY SSF46785 4 87 2.94E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 Gene3D G3DSA:3.40.190.10 177 264 1.2E-27 T 28-03-2018 hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 Gene3D G3DSA:3.40.190.10 89 176 8.1E-10 T 28-03-2018 hmeg3_RS22145 ab183f91ccf65786be779e06445b661d 339 Gene3D G3DSA:1.10.10.10 3 84 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23340 efb881f5a1f817caae047f39ccf87679 249 Pfam PF01925 Sulfite exporter TauE/SafE 10 243 2.5E-20 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS03300 bedfb87cb760eecea3eb81206dd1c84f 71 Pfam PF11174 Protein of unknown function (DUF2970) 14 69 8.5E-26 T 28-03-2018 IPR021344 Protein of unknown function DUF2970 hmeg3_RS03390 be9ba777a2f9678fd64638d5922d8433 208 Pfam PF05995 Cysteine dioxygenase type I 40 167 1.5E-8 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 hmeg3_RS03390 be9ba777a2f9678fd64638d5922d8433 208 SUPERFAMILY SSF51182 5 201 1.11E-53 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS03390 be9ba777a2f9678fd64638d5922d8433 208 Gene3D G3DSA:2.60.120.10 43 194 6.4E-28 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS03390 be9ba777a2f9678fd64638d5922d8433 208 Gene3D G3DSA:1.20.5.440 2 42 2.1E-16 T 28-03-2018 hmeg3_RS06965 908048683572ba208f3c5e0fba677472 218 Pfam PF04403 Paraquat-inducible protein A 43 198 8.3E-56 T 28-03-2018 IPR007498 Paraquat-inducible protein A hmeg3_RS06965 908048683572ba208f3c5e0fba677472 218 Gene3D G3DSA:1.20.1070.10 25 192 5.3E-5 T 28-03-2018 hmeg3_RS21370 9600d0f9e3c15f8ca74aa9c6cb6f5fd2 269 SMART SM00563 65 177 4.5E-34 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS21370 9600d0f9e3c15f8ca74aa9c6cb6f5fd2 269 SUPERFAMILY SSF69593 9 178 7.98E-27 T 28-03-2018 hmeg3_RS21370 9600d0f9e3c15f8ca74aa9c6cb6f5fd2 269 Gene3D G3DSA:3.40.1130.10 30 238 6.0E-30 T 28-03-2018 hmeg3_RS21370 9600d0f9e3c15f8ca74aa9c6cb6f5fd2 269 Pfam PF01553 Acyltransferase 57 173 5.0E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS00375 7031987b25af6c176f8edc743d7087c7 320 Pfam PF09084 NMT1/THI5 like 68 253 8.3E-12 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS00375 7031987b25af6c176f8edc743d7087c7 320 Gene3D G3DSA:3.40.190.10 138 316 4.2E-30 T 28-03-2018 hmeg3_RS00375 7031987b25af6c176f8edc743d7087c7 320 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 34 314 1.2E-60 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 hmeg3_RS00375 7031987b25af6c176f8edc743d7087c7 320 Gene3D G3DSA:3.40.190.10 28 137 5.9E-13 T 28-03-2018 hmeg3_RS00375 7031987b25af6c176f8edc743d7087c7 320 SMART SM00062 33 265 3.7E-9 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS00375 7031987b25af6c176f8edc743d7087c7 320 SUPERFAMILY SSF53850 32 269 1.35E-45 T 28-03-2018 hmeg3_RS24055 a969e2501f6acdd987e9edc33506bba7 414 Pfam PF11340 Protein of unknown function (DUF3142) 101 321 1.1E-80 T 28-03-2018 IPR021488 Protein of unknown function DUF3142 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 1.9E-49 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 Gene3D G3DSA:1.10.520.20 2 106 3.6E-26 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 SUPERFAMILY SSF47928 3 105 9.02E-22 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.583 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 4.3E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 4.3E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 4.3E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 4.3E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 4.3E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS02430 1336fac230eb14546bc971db5f2405f7 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 174 3.5E-40 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 hmeg3_RS14865 1c7e031a01bf181af89637a8862e5615 94 Pfam PF11604 Copper binding periplasmic protein CusF 24 89 6.3E-27 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF hmeg3_RS18665 26cd869613f1cf3281ac45fd1a25e6fd 711 Pfam PF05170 AsmA family 6 576 3.2E-94 T 28-03-2018 IPR007844 AsmA hmeg3_RS02135 90da4d4715dd69fc3b4700bf89934733 309 Pfam PF05425 Copper resistance protein D 195 301 6.5E-25 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 hmeg3_RS14980 cdf9620f936fb10b232c57b7609e0802 236 Gene3D G3DSA:3.30.1060.10 49 224 1.6E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS14980 cdf9620f936fb10b232c57b7609e0802 236 SUPERFAMILY SSF55068 44 218 2.22E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS14980 cdf9620f936fb10b232c57b7609e0802 236 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 51 203 1.7E-49 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS14980 cdf9620f936fb10b232c57b7609e0802 236 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 50 212 35.233 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS14980 cdf9620f936fb10b232c57b7609e0802 236 Pfam PF01625 Peptide methionine sulfoxide reductase 52 206 1.2E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 hmeg3_RS15260 20b999a4110f71e8a9a710f5682816e9 321 Pfam PF01032 FecCD transport family 8 318 2.4E-73 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 hmeg3_RS15260 20b999a4110f71e8a9a710f5682816e9 321 Gene3D G3DSA:1.10.3470.10 1 321 3.2E-53 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS15260 20b999a4110f71e8a9a710f5682816e9 321 SUPERFAMILY SSF81345 7 318 4.58E-65 T 28-03-2018 IPR029022 ABC transporter, BtuC-like hmeg3_RS19460 cbf3c967419f7ea80f8a2b07e6006b85 430 Pfam PF02486 Replication initiation factor 197 373 7.5E-20 T 28-03-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 hmeg3_RS06130 36eff17e009e9c826140ed4b29cb73e8 246 Hamap MF_00597 Probable acetoacetate decarboxylase [adc]. 7 245 58.987 T 28-03-2018 IPR023653 Acetoacetate decarboxylase, bacterial GO:0016831 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 hmeg3_RS06130 36eff17e009e9c826140ed4b29cb73e8 246 Pfam PF06314 Acetoacetate decarboxylase (ADC) 13 244 5.4E-78 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 hmeg3_RS06130 36eff17e009e9c826140ed4b29cb73e8 246 Gene3D G3DSA:2.40.400.10 14 245 2.0E-64 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 hmeg3_RS06130 36eff17e009e9c826140ed4b29cb73e8 246 SUPERFAMILY SSF160104 1 244 4.19E-90 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 119 194 1.2E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 Gene3D G3DSA:3.40.50.1000 1 59 0.31 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 123 200 9.9E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 SUPERFAMILY SSF56784 5 227 1.27E-45 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 4.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 4.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 4.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 199 2.1E-17 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS20410 7fd781cde68f93cdf3cd1020a29ddf0c 229 Gene3D G3DSA:3.40.50.1000 68 229 2.8E-26 T 28-03-2018 IPR023214 HAD-like domain hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 5.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 261 7.0E-65 T 28-03-2018 hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 Gene3D G3DSA:3.40.50.720 1 51 1.8E-6 T 28-03-2018 hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 Gene3D G3DSA:3.40.50.720 52 265 8.3E-65 T 28-03-2018 hmeg3_RS04895 50af1db25f0006e546fb217a6b948430 265 SUPERFAMILY SSF51735 6 262 6.42E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS14940 5974382294f4fc3a44671eecdb92e1d7 256 SMART SM00530 1 56 1.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS14940 5974382294f4fc3a44671eecdb92e1d7 256 Gene3D G3DSA:1.10.260.40 1 97 2.4E-10 T 28-03-2018 hmeg3_RS14940 5974382294f4fc3a44671eecdb92e1d7 256 SUPERFAMILY SSF47413 2 55 1.01E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS14940 5974382294f4fc3a44671eecdb92e1d7 256 Pfam PF01381 Helix-turn-helix 2 55 3.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 SUPERFAMILY SSF63829 6 282 4.91E-59 T 28-03-2018 hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 1.7E-27 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 91 112 1.7E-27 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 197 214 1.7E-27 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 239 257 1.7E-27 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 157 177 1.7E-27 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 Gene3D G3DSA:2.120.10.30 1 293 6.6E-40 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like hmeg3_RS18965 00cf5386cee1760ff0d955f20c04b5e8 293 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 258 3.0E-75 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region hmeg3_RS06220 12833347261c3a6d1deeb1a0a20d9a8b 325 Pfam PF07859 alpha/beta hydrolase fold 89 294 1.5E-36 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 hmeg3_RS06220 12833347261c3a6d1deeb1a0a20d9a8b 325 SUPERFAMILY SSF53474 65 316 2.08E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06220 12833347261c3a6d1deeb1a0a20d9a8b 325 Gene3D G3DSA:3.40.50.1820 46 316 4.4E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01465 1c66334e209beed428aae61b6cb62233 305 Gene3D G3DSA:1.10.3470.10 4 296 1.3E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01465 1c66334e209beed428aae61b6cb62233 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 291 4.6E-42 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS01465 1c66334e209beed428aae61b6cb62233 305 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 13 304 3.7E-115 T 28-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type hmeg3_RS23700 a16ee336fe8ec8ad2b9eaabc285e2e29 419 Gene3D G3DSA:3.90.1300.10 3 414 2.9E-105 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS23700 a16ee336fe8ec8ad2b9eaabc285e2e29 419 Pfam PF01425 Amidase 37 401 3.3E-76 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS23700 a16ee336fe8ec8ad2b9eaabc285e2e29 419 SUPERFAMILY SSF75304 14 413 1.96E-102 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 hmeg3_RS16540 8bc70542b7a66050cae312b6fde53927 442 SUPERFAMILY SSF54373 296 385 4.58E-10 T 28-03-2018 hmeg3_RS16540 8bc70542b7a66050cae312b6fde53927 442 SUPERFAMILY SSF51905 27 80 4.27E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16540 8bc70542b7a66050cae312b6fde53927 442 SUPERFAMILY SSF51905 385 442 4.27E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16540 8bc70542b7a66050cae312b6fde53927 442 SUPERFAMILY SSF51905 142 294 4.27E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16540 8bc70542b7a66050cae312b6fde53927 442 Gene3D G3DSA:3.50.50.60 14 442 4.2E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS16540 8bc70542b7a66050cae312b6fde53927 442 Pfam PF01266 FAD dependent oxidoreductase 28 424 4.5E-49 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS03650 8e467390c0bc896e95bf4c1be6dad4f3 160 Gene3D G3DSA:3.40.1260.10 28 150 3.2E-11 T 28-03-2018 hmeg3_RS03650 8e467390c0bc896e95bf4c1be6dad4f3 160 SUPERFAMILY SSF75169 33 144 1.88E-10 T 28-03-2018 IPR027396 DsrEFH-like hmeg3_RS03650 8e467390c0bc896e95bf4c1be6dad4f3 160 TIGRFAM TIGR04044 MSMEG_0572_fam: MSMEG_0572 family protein 2 160 1.1E-87 T 28-03-2018 IPR023847 Conserved hypothetical protein CHP04044, MSMEG0572 hmeg3_RS18305 137f98c0606b9d7e405fccb7ceb0ade8 151 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 9 148 5.8E-7 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain hmeg3_RS18305 137f98c0606b9d7e405fccb7ceb0ade8 151 SUPERFAMILY SSF54534 9 150 1.02E-26 T 28-03-2018 hmeg3_RS18305 137f98c0606b9d7e405fccb7ceb0ade8 151 Gene3D G3DSA:3.10.50.40 2 151 3.4E-14 T 28-03-2018 hmeg3_RS22045 ecc1304e8e3e6fce7e95bba8b51f6832 90 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 3 76 1.3E-22 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 hmeg3_RS22045 ecc1304e8e3e6fce7e95bba8b51f6832 90 Hamap MF_00910 Cell division protein FtsL [ftsL]. 2 85 15.736 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 hmeg3_RS22045 ecc1304e8e3e6fce7e95bba8b51f6832 90 Pfam PF04999 Cell division protein FtsL 3 85 8.2E-19 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 hmeg3_RS12820 cb7f3d3132af97f95f69d6b52a3ac791 308 Gene3D G3DSA:2.40.160.10 10 308 5.6E-6 T 28-03-2018 hmeg3_RS12820 cb7f3d3132af97f95f69d6b52a3ac791 308 Pfam PF11231 Protein of unknown function (DUF3034) 48 305 2.3E-104 T 28-03-2018 IPR021393 Protein of unknown function DUF3034 hmeg3_RS14810 34bd6c4ee83fa7a2db63a600b166c6c2 240 Gene3D G3DSA:3.40.50.360 22 225 2.6E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS14810 34bd6c4ee83fa7a2db63a600b166c6c2 240 Pfam PF03358 NADPH-dependent FMN reductase 35 177 2.4E-27 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 hmeg3_RS14810 34bd6c4ee83fa7a2db63a600b166c6c2 240 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 8 226 3.9E-123 T 28-03-2018 IPR014063 Arsenate resistance ArsH hmeg3_RS14810 34bd6c4ee83fa7a2db63a600b166c6c2 240 SUPERFAMILY SSF52218 6 226 3.49E-62 T 28-03-2018 IPR029039 Flavoprotein-like domain hmeg3_RS19830 36cc068f576456dc4ab7386e70f9a7bb 261 SUPERFAMILY SSF56524 58 260 1.03E-63 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS19830 36cc068f576456dc4ab7386e70f9a7bb 261 Gene3D G3DSA:3.90.420.10 54 261 9.2E-55 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS19830 36cc068f576456dc4ab7386e70f9a7bb 261 Pfam PF00174 Oxidoreductase molybdopterin binding domain 109 250 7.5E-31 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 hmeg3_RS03190 e81f9a8c0a48b24a854376af8442ed1f 208 Pfam PF04350 Pilus assembly protein, PilO 51 187 7.5E-26 T 28-03-2018 IPR007445 Pilus assembly protein, PilO hmeg3_RS03190 e81f9a8c0a48b24a854376af8442ed1f 208 Gene3D G3DSA:3.30.70.60 97 201 1.4E-14 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 hmeg3_RS01410 4f808b11d8684d687ad4258feabc059b 261 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 50 247 1.1E-81 T 28-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 hmeg3_RS01410 4f808b11d8684d687ad4258feabc059b 261 PIRSF PIRSF028477 1 261 2.3E-66 T 28-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 hmeg3_RS21715 fdc5d746edb642214b2b1377d17557f5 295 Gene3D G3DSA:3.30.1150.10 138 280 3.7E-14 T 28-03-2018 hmeg3_RS21715 fdc5d746edb642214b2b1377d17557f5 295 Pfam PF13103 TonB C terminal 183 266 5.9E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 hmeg3_RS21715 fdc5d746edb642214b2b1377d17557f5 295 SUPERFAMILY SSF74653 167 280 8.89E-13 T 28-03-2018 hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 Gene3D G3DSA:3.40.50.2300 31 158 1.4E-19 T 28-03-2018 hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 Pfam PF13458 Periplasmic binding protein 31 358 8.2E-65 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 Gene3D G3DSA:3.40.50.2300 159 327 1.7E-42 T 28-03-2018 hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 SUPERFAMILY SSF53822 30 360 4.12E-84 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 4.5E-12 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 4.5E-12 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS16940 afe1a6f7a69646a35c478ec262ae0d71 388 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 284 297 4.5E-12 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS10805 0e566962323bcc0313254f4ae7d63103 381 SUPERFAMILY SSF50182 188 253 8.83E-14 T 28-03-2018 IPR010920 LSM domain hmeg3_RS10805 0e566962323bcc0313254f4ae7d63103 381 Pfam PF00924 Mechanosensitive ion channel 146 335 1.4E-22 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 hmeg3_RS10805 0e566962323bcc0313254f4ae7d63103 381 Gene3D G3DSA:2.30.30.60 205 254 8.6E-7 T 28-03-2018 hmeg3_RS23290 54b1c7b0d29f23b32424a157ad456f51 310 Pfam PF03547 Membrane transport protein 4 146 1.5E-15 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 hmeg3_RS23290 54b1c7b0d29f23b32424a157ad456f51 310 Pfam PF03547 Membrane transport protein 159 304 6.6E-17 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 hmeg3_RS12165 9a8806c10c58183a38b2b9d601e50eb8 275 SUPERFAMILY SSF51735 12 236 1.64E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS12165 9a8806c10c58183a38b2b9d601e50eb8 275 Gene3D G3DSA:3.40.50.720 11 237 7.7E-34 T 28-03-2018 hmeg3_RS12165 9a8806c10c58183a38b2b9d601e50eb8 275 Pfam PF01370 NAD dependent epimerase/dehydratase family 14 172 3.1E-18 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS05235 13d64155c0e3b7817f274e157ace6b6d 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 277 1.0E-35 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS05235 13d64155c0e3b7817f274e157ace6b6d 288 Gene3D G3DSA:1.10.3470.10 1 282 4.0E-46 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS16855 69932d085932e96690ba625f12e135e0 333 Pfam PF00248 Aldo/keto reductase family 16 310 1.2E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS16855 69932d085932e96690ba625f12e135e0 333 SUPERFAMILY SSF51430 1 310 2.49E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS16855 69932d085932e96690ba625f12e135e0 333 Gene3D G3DSA:3.20.20.100 1 332 1.9E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS23775 2c6d2966e943414f1daf29a1eda58dee 479 Gene3D G3DSA:3.40.605.10 1 267 3.1E-91 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS23775 2c6d2966e943414f1daf29a1eda58dee 479 SUPERFAMILY SSF53720 7 476 6.94E-154 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS23775 2c6d2966e943414f1daf29a1eda58dee 479 Pfam PF00171 Aldehyde dehydrogenase family 17 475 9.1E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS23775 2c6d2966e943414f1daf29a1eda58dee 479 Gene3D G3DSA:3.40.309.10 268 462 4.8E-63 T 28-03-2018 hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 68 137 7.6E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 SUPERFAMILY SSF101801 64 146 2.09E-25 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 64 138 1.3E-32 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 113 128 2.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 67 83 2.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 100 113 2.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 84 100 2.1E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 hmeg3_RS08280 31cc576be2211869567a61efef0c8b69 148 Gene3D G3DSA:2.30.330.10 53 148 1.1E-29 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 205 217 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 PRINTS PR00084 Mannitol dehydrogenase signature 12 22 2.2E-16 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 PRINTS PR00084 Mannitol dehydrogenase signature 205 218 2.2E-16 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 PRINTS PR00084 Mannitol dehydrogenase signature 235 250 2.2E-16 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 PRINTS PR00084 Mannitol dehydrogenase signature 165 178 2.2E-16 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 SUPERFAMILY SSF48179 271 459 1.05E-44 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 204 437 1.4E-72 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 SUPERFAMILY SSF51735 9 268 2.87E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 Gene3D G3DSA:1.10.1040.10 270 468 1.9E-48 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 Gene3D G3DSA:3.40.50.720 2 268 3.0E-82 T 28-03-2018 hmeg3_RS21480 938af14ae6e8ef20f9b4d85035717a22 470 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 12 174 3.4E-32 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 hmeg3_RS23265 d0caba99a6313d49469fe1249432c9a0 109 Pfam PF12779 YXWGXW repeat (2 copies) 54 78 3.3E-9 T 28-03-2018 IPR024447 YXWGXW repeat hmeg3_RS14505 ad53bcea1bb641f0a787aefc279fb1ed 310 Pfam PF00892 EamA-like transporter family 162 299 1.3E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS14505 ad53bcea1bb641f0a787aefc279fb1ed 310 Pfam PF00892 EamA-like transporter family 14 147 2.5E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS14505 ad53bcea1bb641f0a787aefc279fb1ed 310 SUPERFAMILY SSF103481 217 302 2.62E-8 T 28-03-2018 hmeg3_RS14505 ad53bcea1bb641f0a787aefc279fb1ed 310 SUPERFAMILY SSF103481 47 150 3.92E-14 T 28-03-2018 hmeg3_RS11260 01b278df25e9b752355a60943cfe977f 156 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 40 113 2.2E-17 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 hmeg3_RS11260 01b278df25e9b752355a60943cfe977f 156 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 33 129 3.6E-34 T 28-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 hmeg3_RS04700 fe02ace28c4884721f212c1baa3ed574 208 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 49 207 4.3E-38 T 28-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 hmeg3_RS04700 fe02ace28c4884721f212c1baa3ed574 208 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 8 208 28.721 T 28-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 hmeg3_RS04700 fe02ace28c4884721f212c1baa3ed574 208 Gene3D G3DSA:1.20.1260.10 38 183 1.2E-18 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS04700 fe02ace28c4884721f212c1baa3ed574 208 SUPERFAMILY SSF47240 47 181 8.12E-13 T 28-03-2018 IPR009078 Ferritin-like superfamily hmeg3_RS17745 a3b992652eece2a9bbc3326f6b81ec1f 201 Pfam PF02417 Chromate transporter 18 174 1.3E-29 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 hmeg3_RS11915 0f1fcedda26b0a6767b0e252d80bf184 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 195 244 1.8E-8 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS11915 0f1fcedda26b0a6767b0e252d80bf184 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 20 71 2.0E-18 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS11915 0f1fcedda26b0a6767b0e252d80bf184 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 75 122 1.4E-13 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS11915 0f1fcedda26b0a6767b0e252d80bf184 254 Pfam PF03988 Repeat of Unknown Function (DUF347) 140 191 2.1E-16 T 28-03-2018 IPR007136 Protein of unknown function DUF347 hmeg3_RS21600 16d3dc8882ea014924a7b84e41e799b3 150 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 30 148 4.4E-34 T 28-03-2018 IPR019223 Domain of unknown function DUF2147 hmeg3_RS17115 623c7cafc606248e13963b73820b6717 374 SUPERFAMILY SSF51197 5 289 5.49E-75 T 28-03-2018 hmeg3_RS17115 623c7cafc606248e13963b73820b6717 374 Pfam PF08007 Cupin superfamily protein 13 313 1.0E-90 T 28-03-2018 IPR003347 JmjC domain hmeg3_RS17115 623c7cafc606248e13963b73820b6717 374 SMART SM00558 77 218 0.0011 T 28-03-2018 IPR003347 JmjC domain hmeg3_RS17115 623c7cafc606248e13963b73820b6717 374 Gene3D G3DSA:2.60.120.650 4 209 1.4E-31 T 28-03-2018 hmeg3_RS23570 505400cb83c82547ba05d64d823dc3a4 323 Pfam PF00892 EamA-like transporter family 184 313 1.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS23570 505400cb83c82547ba05d64d823dc3a4 323 Pfam PF00892 EamA-like transporter family 37 169 1.5E-23 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS23570 505400cb83c82547ba05d64d823dc3a4 323 SUPERFAMILY SSF103481 69 172 1.23E-14 T 28-03-2018 hmeg3_RS23570 505400cb83c82547ba05d64d823dc3a4 323 SUPERFAMILY SSF103481 221 321 8.63E-14 T 28-03-2018 hmeg3_RS18885 30062e200a345f732b09ea9b6b0a70c6 164 Gene3D G3DSA:2.30.110.10 1 158 1.0E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS18885 30062e200a345f732b09ea9b6b0a70c6 164 SUPERFAMILY SSF50475 7 158 2.8E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS18885 30062e200a345f732b09ea9b6b0a70c6 164 SMART SM00903 11 157 3.1E-46 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS18885 30062e200a345f732b09ea9b6b0a70c6 164 Pfam PF01613 Flavin reductase like domain 11 158 1.5E-30 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 hmeg3_RS10160 a36209e7efb4ce79960dc2f6e5de7dfe 277 Gene3D G3DSA:3.40.50.1820 2 254 3.0E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS10160 a36209e7efb4ce79960dc2f6e5de7dfe 277 SUPERFAMILY SSF53474 6 252 1.51E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS10160 a36209e7efb4ce79960dc2f6e5de7dfe 277 PIRSF PIRSF017388 1 254 1.1E-37 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 hmeg3_RS10160 a36209e7efb4ce79960dc2f6e5de7dfe 277 Pfam PF12146 Serine aminopeptidase, S33 6 240 9.7E-15 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS23000 775ae00d1511049ad77f316094eaa578 431 Pfam PF08886 Glutamate-cysteine ligase 17 421 9.8E-198 T 28-03-2018 IPR011718 Glutamate--cysteine ligase GshA hmeg3_RS23000 775ae00d1511049ad77f316094eaa578 431 Gene3D G3DSA:3.30.470.20 247 376 8.6E-4 T 28-03-2018 hmeg3_RS23000 775ae00d1511049ad77f316094eaa578 431 TIGRFAM TIGR02049 gshA_ferroox: glutamate--cysteine ligase 17 424 5.7E-189 T 28-03-2018 IPR011718 Glutamate--cysteine ligase GshA hmeg3_RS15150 d9589d823597eb95443b4ca1356bdd79 263 Gene3D G3DSA:3.90.226.10 7 216 1.1E-50 T 28-03-2018 hmeg3_RS15150 d9589d823597eb95443b4ca1356bdd79 263 Gene3D G3DSA:1.10.12.10 217 260 4.7E-10 T 28-03-2018 IPR014748 Crontonase, C-terminal hmeg3_RS15150 d9589d823597eb95443b4ca1356bdd79 263 SUPERFAMILY SSF52096 10 261 5.81E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS15150 d9589d823597eb95443b4ca1356bdd79 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 259 2.2E-51 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 hmeg3_RS04955 9096c1745cbf08fd05c93eab58ec3e66 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 291 6.6E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04955 9096c1745cbf08fd05c93eab58ec3e66 294 Gene3D G3DSA:1.10.3720.10 12 293 6.7E-45 T 28-03-2018 hmeg3_RS04955 9096c1745cbf08fd05c93eab58ec3e66 294 SUPERFAMILY SSF161098 55 281 1.1E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14025 5cae86e487ca71b951857f1d0b7568a8 159 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 130 6.0E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS14025 5cae86e487ca71b951857f1d0b7568a8 159 Gene3D G3DSA:3.10.180.10 9 145 7.6E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS14025 5cae86e487ca71b951857f1d0b7568a8 159 SUPERFAMILY SSF54593 12 149 3.89E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 2.1E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 72 90 2.1E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 288 301 2.1E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 340 355 2.1E-8 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 Gene3D G3DSA:3.40.50.2300 202 363 1.9E-19 T 28-03-2018 hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 SUPERFAMILY SSF53822 31 386 1.21E-80 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 Gene3D G3DSA:3.40.50.2300 15 201 1.6E-29 T 28-03-2018 hmeg3_RS19225 6f20fee84ff709838b7e0687023195ab 404 Pfam PF13458 Periplasmic binding protein 46 370 6.2E-69 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 TIGRFAM TIGR02516 type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family 42 528 1.4E-130 T 28-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 312 332 1.4E-35 T 28-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 416 431 1.4E-35 T 28-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 196 213 1.4E-35 T 28-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 382 401 1.4E-35 T 28-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 506 525 1.4E-35 T 28-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 Pfam PF00263 Bacterial type II and III secretion system protein 369 525 5.6E-33 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 hmeg3_RS15840 3407deb71e37d7ef08820452ab6d7e0c 569 Pfam PF03958 Bacterial type II/III secretion system short domain 184 309 2.6E-14 T 28-03-2018 IPR005644 NolW-like hmeg3_RS11405 d11178de2bdad3fb61e98b10b48fc1f4 275 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 11 254 1.1E-91 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 hmeg3_RS11405 d11178de2bdad3fb61e98b10b48fc1f4 275 PIRSF PIRSF018982 1 264 2.3E-93 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 hmeg3_RS14255 2343bc2312584ddb3725786a3ef4b41f 408 Pfam PF02653 Branched-chain amino acid transport system / permease component 104 389 2.0E-53 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS14255 2343bc2312584ddb3725786a3ef4b41f 408 Gene3D G3DSA:1.10.3470.10 37 392 1.5E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS14255 2343bc2312584ddb3725786a3ef4b41f 408 Pfam PF11862 Domain of unknown function (DUF3382) 5 94 1.4E-22 T 28-03-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal hmeg3_RS23560 27635984fa6b4d60b778fc9693098fd0 135 SUPERFAMILY SSF82784 15 133 2.36E-28 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS23560 27635984fa6b4d60b778fc9693098fd0 135 Gene3D G3DSA:3.30.300.20 4 135 2.1E-24 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta hmeg3_RS23560 27635984fa6b4d60b778fc9693098fd0 135 Pfam PF02566 OsmC-like protein 37 130 8.6E-17 T 28-03-2018 IPR003718 OsmC/Ohr family hmeg3_RS13525 bd11435ab4630306219bedc7198f50a2 123 SUPERFAMILY SSF54593 1 118 2.89E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS13525 bd11435ab4630306219bedc7198f50a2 123 Gene3D G3DSA:3.10.180.10 1 123 6.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS11815 9847e409c24a47456a40b4499f300310 44 Pfam PF09722 Protein of unknown function (DUF2384) 1 39 1.1E-8 T 28-03-2018 IPR024467 Domain of unknown function DUF2384 hmeg3_RS19985 eb14172d6b58f8c7c2d884905354e186 244 Pfam PF01618 MotA/TolQ/ExbB proton channel family 75 206 5.7E-35 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 hmeg3_RS07260 c5b7d8fb15c68ffee3cc4b8c62fa3c9c 319 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 6 314 4.1E-156 T 28-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 hmeg3_RS07260 c5b7d8fb15c68ffee3cc4b8c62fa3c9c 319 SUPERFAMILY SSF88713 5 313 5.0E-84 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 hmeg3_RS07260 c5b7d8fb15c68ffee3cc4b8c62fa3c9c 319 Gene3D G3DSA:3.20.20.370 2 318 5.4E-57 T 28-03-2018 hmeg3_RS07260 c5b7d8fb15c68ffee3cc4b8c62fa3c9c 319 Pfam PF01522 Polysaccharide deacetylase 76 179 3.0E-11 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 hmeg3_RS13535 1e8b12414b4d78807568d5dc2d064a3d 165 Pfam PF13924 Lipocalin-like domain 31 135 1.1E-18 T 28-03-2018 IPR024311 Lipocalin-like domain hmeg3_RS20280 8f5251584c8a45188b2773e48efcfc5c 362 Pfam PF01594 AI-2E family transporter 14 348 3.0E-54 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 SMART SM00283 266 513 8.1E-90 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 SUPERFAMILY SSF58104 233 513 1.44E-74 T 28-03-2018 hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 183 4.9E-17 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.8E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 Gene3D G3DSA:1.10.287.950 322 513 1.1E-46 T 28-03-2018 hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 Gene3D G3DSA:1.10.287.950 91 321 4.0E-21 T 28-03-2018 hmeg3_RS06340 c3cbcfebaaf763dd34c13cd4fee8c05e 513 SMART SM00304 213 265 7.6E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 hmeg3_RS17370 814365fbd79cb477b0a20526a66fd9f2 294 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 86 284 3.3E-64 T 28-03-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 hmeg3_RS17370 814365fbd79cb477b0a20526a66fd9f2 294 Gene3D G3DSA:1.10.3720.10 7 294 1.7E-26 T 28-03-2018 hmeg3_RS17370 814365fbd79cb477b0a20526a66fd9f2 294 SUPERFAMILY SSF161098 98 283 6.02E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17370 814365fbd79cb477b0a20526a66fd9f2 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 290 3.5E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23530 2d7436851bb6f5ebcafeaeaaefcde03c 232 SUPERFAMILY SSF161098 19 213 8.76E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23530 2d7436851bb6f5ebcafeaeaaefcde03c 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 122 2.6E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS23530 2d7436851bb6f5ebcafeaeaaefcde03c 232 Gene3D G3DSA:1.10.3720.10 4 232 1.0E-42 T 28-03-2018 hmeg3_RS23530 2d7436851bb6f5ebcafeaeaaefcde03c 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 228 6.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS11880 1759ac7a437a15953ce629e90e7c8e07 339 Pfam PF11740 Plasmid replication region DNA-binding N-term 8 112 4.6E-23 T 28-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain hmeg3_RS11880 1759ac7a437a15953ce629e90e7c8e07 339 Gene3D G3DSA:1.20.5.340 40 189 0.092 T 28-03-2018 hmeg3_RS11880 1759ac7a437a15953ce629e90e7c8e07 339 Gene3D G3DSA:1.20.5.340 190 259 6.8E-4 T 28-03-2018 hmeg3_RS11880 1759ac7a437a15953ce629e90e7c8e07 339 Gene3D G3DSA:1.20.5.340 260 335 0.001 T 28-03-2018 hmeg3_RS22455 39cf47daeb8274e6b531438c578bcaea 87 Pfam PF13627 Prokaryotic lipoprotein-attachment site 17 38 3.9E-9 T 28-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site hmeg3_RS12020 4a92b445189da26ecbcb242a58d42f15 444 SUPERFAMILY SSF161098 221 433 1.44E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12020 4a92b445189da26ecbcb242a58d42f15 444 Gene3D G3DSA:1.10.3720.10 47 439 6.0E-41 T 28-03-2018 hmeg3_RS12020 4a92b445189da26ecbcb242a58d42f15 444 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 253 437 3.5E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00965 ac00dc46f3bb2027f383985749721b8a 468 Pfam PF02321 Outer membrane efflux protein 60 252 3.7E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00965 ac00dc46f3bb2027f383985749721b8a 468 Pfam PF02321 Outer membrane efflux protein 277 447 3.0E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00965 ac00dc46f3bb2027f383985749721b8a 468 SUPERFAMILY SSF56954 3 465 5.62E-94 T 28-03-2018 hmeg3_RS00965 ac00dc46f3bb2027f383985749721b8a 468 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 7 463 1.1E-132 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS00965 ac00dc46f3bb2027f383985749721b8a 468 Gene3D G3DSA:1.20.1600.10 19 468 2.8E-86 T 28-03-2018 hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 SUPERFAMILY SSF50331 245 336 1.53E-5 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 SUPERFAMILY SSF52540 4 242 2.23E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 Pfam PF00005 ABC transporter 21 162 4.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 SMART SM00382 29 212 1.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 Gene3D G3DSA:3.40.50.300 1 242 6.2E-73 T 28-03-2018 hmeg3_RS19145 24c93f75c5f7f813c2aa748119ea09cb 338 Pfam PF08402 TOBE domain 271 336 2.6E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 hmeg3_RS04780 2dc0c90df14b66bad18514e301fcb491 264 Pfam PF02535 ZIP Zinc transporter 96 257 2.4E-33 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 hmeg3_RS03335 6620be14a61c5eb68c30a6c56b0e8cd9 197 Pfam PF02630 SCO1/SenC 37 175 2.1E-39 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS03335 6620be14a61c5eb68c30a6c56b0e8cd9 197 SUPERFAMILY SSF52833 40 196 3.3E-53 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03335 6620be14a61c5eb68c30a6c56b0e8cd9 197 Gene3D G3DSA:3.40.30.10 31 196 1.1E-36 T 28-03-2018 hmeg3_RS22135 b80cf192a23709d9b8cf0e3137aa47e9 335 Pfam PF00248 Aldo/keto reductase family 16 310 6.1E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS22135 b80cf192a23709d9b8cf0e3137aa47e9 335 Gene3D G3DSA:3.20.20.100 3 313 3.8E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS22135 b80cf192a23709d9b8cf0e3137aa47e9 335 SUPERFAMILY SSF51430 1 312 2.36E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain hmeg3_RS22135 b80cf192a23709d9b8cf0e3137aa47e9 335 PRINTS PR00069 Aldo-keto reductase signature 134 151 9.1E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22135 b80cf192a23709d9b8cf0e3137aa47e9 335 PRINTS PR00069 Aldo-keto reductase signature 103 121 9.1E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS22135 b80cf192a23709d9b8cf0e3137aa47e9 335 PRINTS PR00069 Aldo-keto reductase signature 39 63 9.1E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 hmeg3_RS15925 24277e63a183e46221523ad5c1483d6b 1326 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 977 1325 4.2E-62 T 28-03-2018 IPR007452 Translocation and assembly module TamB hmeg3_RS01340 d2d3a38a18c8cddf92d82c3ee6ea58e8 236 SMART SM00382 29 213 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain hmeg3_RS01340 d2d3a38a18c8cddf92d82c3ee6ea58e8 236 Gene3D G3DSA:3.40.50.300 1 236 3.0E-53 T 28-03-2018 hmeg3_RS01340 d2d3a38a18c8cddf92d82c3ee6ea58e8 236 SUPERFAMILY SSF52540 3 234 2.46E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS01340 d2d3a38a18c8cddf92d82c3ee6ea58e8 236 Pfam PF00005 ABC transporter 22 164 1.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS01340 d2d3a38a18c8cddf92d82c3ee6ea58e8 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 hmeg3_RS05375 522b4ee5e837c92b82b51e236944e947 235 Pfam PF06912 Protein of unknown function (DUF1275) 13 219 1.7E-26 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 SUPERFAMILY SSF51182 13 74 3.16E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 SUPERFAMILY SSF46689 195 246 1.57E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 SMART SM00342 159 242 1.7E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 Pfam PF12833 Helix-turn-helix domain 165 244 3.6E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 SUPERFAMILY SSF46689 143 192 6.27E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 Gene3D G3DSA:1.10.10.60 139 198 1.1E-9 T 28-03-2018 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 Gene3D G3DSA:1.10.10.60 199 247 2.4E-15 T 28-03-2018 hmeg3_RS18650 1b45d5059f84e4724ecc1d2aba1405b7 247 Gene3D G3DSA:2.60.120.10 9 89 6.7E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS00240 1253a39da24188ba562f2f6a95ceeaba 115 SMART SM00749 51 114 0.001 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria hmeg3_RS00240 1253a39da24188ba562f2f6a95ceeaba 115 Pfam PF04972 BON domain 46 113 1.0E-17 T 28-03-2018 IPR007055 BON domain hmeg3_RS02400 fdd94ace6d7e593725f7cc4f8064095a 452 Pfam PF06527 TniQ 38 172 1.8E-17 T 28-03-2018 IPR009492 TniQ hmeg3_RS06245 77fb15ffcea8e90dbd1476cbea2a27ec 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 79 6.8E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain hmeg3_RS06245 77fb15ffcea8e90dbd1476cbea2a27ec 100 SUPERFAMILY SSF54909 3 96 1.16E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS06245 77fb15ffcea8e90dbd1476cbea2a27ec 100 Gene3D G3DSA:3.30.70.100 1 98 4.2E-19 T 28-03-2018 hmeg3_RS13275 3787c743a6d57f9945af131b3197521a 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 57 3.4E-19 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS13275 3787c743a6d57f9945af131b3197521a 67 Gene3D G3DSA:3.90.940.10 1 66 8.4E-21 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 hmeg3_RS13275 3787c743a6d57f9945af131b3197521a 67 Pfam PF01192 RNA polymerase Rpb6 8 58 2.8E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 hmeg3_RS13275 3787c743a6d57f9945af131b3197521a 67 SUPERFAMILY SSF63562 1 63 3.14E-21 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 hmeg3_RS13275 3787c743a6d57f9945af131b3197521a 67 SMART SM01409 8 59 1.6E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 hmeg3_RS13275 3787c743a6d57f9945af131b3197521a 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 16.556 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 hmeg3_RS15620 fcd4693e9edeb6fddb4bd1b9a4efc08a 306 Gene3D G3DSA:3.40.50.1820 9 297 7.2E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS15620 fcd4693e9edeb6fddb4bd1b9a4efc08a 306 Pfam PF00326 Prolyl oligopeptidase family 99 189 1.7E-9 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 hmeg3_RS15620 fcd4693e9edeb6fddb4bd1b9a4efc08a 306 SUPERFAMILY SSF53474 55 296 1.92E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 SUPERFAMILY SSF51735 2 341 3.81E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 Gene3D G3DSA:3.90.25.10 249 361 6.4E-35 T 28-03-2018 hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 Gene3D G3DSA:3.90.25.10 207 248 3.0E-25 T 28-03-2018 hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 335 4.8E-159 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 342 4.0E-179 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 Gene3D G3DSA:3.40.50.720 1 206 4.9E-26 T 28-03-2018 hmeg3_RS21350 c4e5a8ad0ed8c0a3d3bf2431257fc287 361 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 345 56.191 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 Gene3D G3DSA:2.40.50.100 20 85 6.0E-28 T 28-03-2018 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 2.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 SUPERFAMILY SSF110324 2 82 2.44E-33 T 28-03-2018 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 Pfam PF01016 Ribosomal L27 protein 2 82 1.1E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.6E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.6E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.6E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.994 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS21880 a388f5f24e9f298e20bdbe72d7bd384a 89 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 43 75 6.0E-8 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 hmeg3_RS00775 b1836ecb0d8f4ea7a3d5e1582943c49e 181 Gene3D G3DSA:3.40.30.10 36 180 7.2E-35 T 28-03-2018 hmeg3_RS00775 b1836ecb0d8f4ea7a3d5e1582943c49e 181 SUPERFAMILY SSF52833 39 180 3.08E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS00775 b1836ecb0d8f4ea7a3d5e1582943c49e 181 Pfam PF08534 Redoxin 42 170 3.6E-26 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 Gene3D G3DSA:3.40.190.80 161 269 8.5E-16 T 28-03-2018 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 7.3E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 7.3E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 144 167 7.3E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 76 92 7.3E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 54 74 7.3E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 SUPERFAMILY SSF56655 19 268 1.13E-57 T 28-03-2018 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 Pfam PF00459 Inositol monophosphatase family 19 266 2.1E-41 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 Gene3D G3DSA:3.30.540.10 16 160 2.1E-35 T 28-03-2018 hmeg3_RS09330 12449db5ab926eae936d2d43730fc494 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 96 109 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site hmeg3_RS07080 4710b643268cbfd6f6e3916abc024eec 347 Gene3D G3DSA:3.40.190.10 144 347 3.9E-23 T 28-03-2018 hmeg3_RS07080 4710b643268cbfd6f6e3916abc024eec 347 Pfam PF09084 NMT1/THI5 like 59 271 9.5E-24 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS07080 4710b643268cbfd6f6e3916abc024eec 347 SUPERFAMILY SSF53850 40 286 2.61E-35 T 28-03-2018 hmeg3_RS07080 4710b643268cbfd6f6e3916abc024eec 347 Gene3D G3DSA:3.40.190.10 38 143 5.2E-13 T 28-03-2018 hmeg3_RS19050 5406a5a781c56340a8137a1bf39291b5 386 Pfam PF07690 Major Facilitator Superfamily 8 339 5.0E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS19050 5406a5a781c56340a8137a1bf39291b5 386 Gene3D G3DSA:1.20.1250.20 1 183 1.6E-32 T 28-03-2018 hmeg3_RS19050 5406a5a781c56340a8137a1bf39291b5 386 Gene3D G3DSA:1.20.1250.20 188 381 7.6E-14 T 28-03-2018 hmeg3_RS19050 5406a5a781c56340a8137a1bf39291b5 386 SUPERFAMILY SSF103473 3 375 4.32E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS20470 d5a1db9951a2f99c1b9c370980a9d1ef 339 SUPERFAMILY SSF53850 28 332 6.27E-63 T 28-03-2018 hmeg3_RS20470 d5a1db9951a2f99c1b9c370980a9d1ef 339 Gene3D G3DSA:3.40.190.10 143 336 2.6E-33 T 28-03-2018 hmeg3_RS20470 d5a1db9951a2f99c1b9c370980a9d1ef 339 Pfam PF13343 Bacterial extracellular solute-binding protein 79 306 5.3E-52 T 28-03-2018 hmeg3_RS20470 d5a1db9951a2f99c1b9c370980a9d1ef 339 Gene3D G3DSA:3.40.190.10 28 142 9.0E-7 T 28-03-2018 hmeg3_RS01685 33957754b15a228c8343a44aafaeaff0 307 SUPERFAMILY SSF103481 208 291 3.53E-7 T 28-03-2018 hmeg3_RS01685 33957754b15a228c8343a44aafaeaff0 307 Pfam PF00892 EamA-like transporter family 161 285 1.4E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS01685 33957754b15a228c8343a44aafaeaff0 307 SUPERFAMILY SSF103481 46 140 4.32E-6 T 28-03-2018 hmeg3_RS13980 5112e3f1b7e70a566d7308a5ad135bf6 163 Pfam PF06271 RDD family 4 150 5.3E-19 T 28-03-2018 IPR010432 RDD hmeg3_RS17405 bbccdc622ebdb7ba5729cf53cf40a1af 491 Pfam PF01554 MatE 33 194 6.2E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS17405 bbccdc622ebdb7ba5729cf53cf40a1af 491 Pfam PF01554 MatE 262 422 7.9E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS17405 bbccdc622ebdb7ba5729cf53cf40a1af 491 TIGRFAM TIGR00797 matE: MATE efflux family protein 33 435 1.2E-69 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS17405 bbccdc622ebdb7ba5729cf53cf40a1af 491 PIRSF PIRSF006603 10 469 1.1E-117 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 hmeg3_RS07355 ccfbfb236aa7d0aaa29b7e735459520e 117 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 102 9.2E-7 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 hmeg3_RS07355 ccfbfb236aa7d0aaa29b7e735459520e 117 Gene3D G3DSA:3.90.1590.10 1 115 3.2E-23 T 28-03-2018 hmeg3_RS07355 ccfbfb236aa7d0aaa29b7e735459520e 117 SUPERFAMILY SSF51316 1 112 1.46E-26 T 28-03-2018 IPR011057 Mss4-like hmeg3_RS21785 68ca32fa3c79b5d3c923f41ad59b9cb4 180 Pfam PF02325 YGGT family 105 171 2.4E-16 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 hmeg3_RS21785 68ca32fa3c79b5d3c923f41ad59b9cb4 180 Pfam PF02325 YGGT family 13 79 5.1E-13 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 hmeg3_RS15720 50ff84504f5b36feb5a46d728482d2d8 243 ProDom PD038222 INVASION PLASMID OXYGEN-REGULATED III SECRETION MXIN TYPE SYSTEM PATHWAY ORGB 18 187 1.0E-8 T 28-03-2018 hmeg3_RS16110 ddf06e91222609617e82eb55498a6e8e 75 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 65 2.3E-28 T 28-03-2018 IPR021074 Formate dehydrogenase, delta subunit hmeg3_RS16705 b2ff3c5c6a22f299039ca0f37eb3d0c3 341 Pfam PF03888 MucB/RseB N-terminal domain 37 211 1.7E-62 T 28-03-2018 IPR033434 MucB/RseB, N-terminal hmeg3_RS16705 b2ff3c5c6a22f299039ca0f37eb3d0c3 341 Gene3D G3DSA:2.50.20.10 31 283 1.3E-26 T 28-03-2018 hmeg3_RS16705 b2ff3c5c6a22f299039ca0f37eb3d0c3 341 Pfam PF17188 MucB/RseB C-terminal domain 231 337 2.3E-27 T 28-03-2018 IPR033436 MucB/RseB, C-terminal hmeg3_RS16705 b2ff3c5c6a22f299039ca0f37eb3d0c3 341 PIRSF PIRSF005427 1 341 1.2E-96 T 28-03-2018 IPR005588 MucB/RseB hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 122 11.321 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 Gene3D G3DSA:1.20.5.1030 67 118 3.8E-18 T 28-03-2018 hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 118 1.0E-18 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 PRINTS PR01650 Bacterial translocase SecE signature 43 64 4.8E-15 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 PRINTS PR01650 Bacterial translocase SecE signature 64 84 4.8E-15 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 PRINTS PR01650 Bacterial translocase SecE signature 88 108 4.8E-15 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 hmeg3_RS22935 321f283074131801115ff565c2f155c5 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 118 3.5E-17 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 hmeg3_RS23270 ea39e6c9f17116281b6e277dce164e3a 208 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 125 5.1E-16 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 hmeg3_RS23270 ea39e6c9f17116281b6e277dce164e3a 208 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 13 208 6.9E-80 T 28-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent hmeg3_RS23270 ea39e6c9f17116281b6e277dce164e3a 208 SUPERFAMILY SSF50475 25 179 8.48E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS23270 ea39e6c9f17116281b6e277dce164e3a 208 Gene3D G3DSA:2.30.110.10 25 178 9.8E-29 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 hmeg3_RS00295 9c8570b7fafc2ad7f578c43b1eb8e288 107 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 8.9E-48 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00295 9c8570b7fafc2ad7f578c43b1eb8e288 107 Gene3D G3DSA:2.10.150.10 1 101 9.6E-47 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00295 9c8570b7fafc2ad7f578c43b1eb8e288 107 Pfam PF00699 Urease beta subunit 3 99 1.3E-45 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00295 9c8570b7fafc2ad7f578c43b1eb8e288 107 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 32.111 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS00295 9c8570b7fafc2ad7f578c43b1eb8e288 107 SUPERFAMILY SSF51278 1 105 1.19E-48 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 Gene3D G3DSA:3.40.1080.10 236 499 3.1E-60 T 28-03-2018 hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 Gene3D G3DSA:3.40.1080.10 12 235 6.5E-34 T 28-03-2018 hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 12 493 3.0E-222 T 28-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 318 461 1.5E-41 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 SUPERFAMILY SSF100950 8 220 5.86E-67 T 28-03-2018 hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 SUPERFAMILY SSF100950 224 494 1.67E-80 T 28-03-2018 hmeg3_RS18625 a828406dbadba321fabda945380ceeb2 500 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 12 213 1.6E-25 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 hmeg3_RS08030 0d8300cbe020c24d79426dffc32254c3 124 Pfam PF01042 Endoribonuclease L-PSP 9 120 7.0E-23 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS08030 0d8300cbe020c24d79426dffc32254c3 124 SUPERFAMILY SSF55298 8 122 3.61E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS08030 0d8300cbe020c24d79426dffc32254c3 124 Gene3D G3DSA:3.30.1330.40 1 124 2.4E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS19155 5f435ea866952ebf8617a9c88e9f743b 355 Pfam PF00962 Adenosine/AMP deaminase 18 339 2.6E-38 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 hmeg3_RS19155 5f435ea866952ebf8617a9c88e9f743b 355 Gene3D G3DSA:3.20.20.140 1 354 7.7E-64 T 28-03-2018 hmeg3_RS19155 5f435ea866952ebf8617a9c88e9f743b 355 SUPERFAMILY SSF51556 13 352 4.09E-58 T 28-03-2018 IPR032466 Metal-dependent hydrolase hmeg3_RS07940 d426a0e3a9f5ecd5398ce93b124d8798 188 Pfam PF10986 Protein of unknown function (DUF2796) 28 182 6.9E-45 T 28-03-2018 IPR021253 Protein of unknown function DUF2796 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Pfam PF12773 Double zinc ribbon 381 424 7.7E-8 T 28-03-2018 IPR025874 Double zinc ribbon hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Pfam PF12773 Double zinc ribbon 323 374 1.1E-9 T 28-03-2018 IPR025874 Double zinc ribbon hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Gene3D G3DSA:2.20.28.20 317 350 3.7E-4 T 28-03-2018 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Gene3D G3DSA:2.20.28.20 405 429 3.7E-4 T 28-03-2018 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Gene3D G3DSA:2.20.28.20 353 379 0.074 T 28-03-2018 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Gene3D G3DSA:2.20.28.20 430 456 0.0014 T 28-03-2018 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Gene3D G3DSA:2.20.28.20 380 403 0.002 T 28-03-2018 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 SUPERFAMILY SSF117892 130 233 5.49E-6 T 28-03-2018 IPR001107 Band 7 domain hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Pfam PF13240 zinc-ribbon domain 431 451 1.5E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 hmeg3_RS09685 0af9b5f3f14cf32c334b8a1c9a1980b6 456 Pfam PF13421 SPFH domain-Band 7 family 33 251 2.8E-56 T 28-03-2018 IPR033880 SPFH domain, YdjI-like hmeg3_RS09520 36fe41b61eb9797db9ebe46bb7b0e5d5 90 SUPERFAMILY SSF47413 7 70 4.79E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS09520 36fe41b61eb9797db9ebe46bb7b0e5d5 90 Gene3D G3DSA:1.10.260.40 2 78 1.8E-16 T 28-03-2018 hmeg3_RS09520 36fe41b61eb9797db9ebe46bb7b0e5d5 90 Pfam PF01381 Helix-turn-helix 13 65 5.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS09520 36fe41b61eb9797db9ebe46bb7b0e5d5 90 SMART SM00530 12 67 6.5E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS21255 6b08cf1dcf340c39ed6790ef1dafe222 408 Pfam PF08484 C-methyltransferase C-terminal domain 244 402 1.9E-63 T 28-03-2018 IPR013691 C-methyltransferase hmeg3_RS21255 6b08cf1dcf340c39ed6790ef1dafe222 408 Pfam PF13489 Methyltransferase domain 84 238 4.3E-10 T 28-03-2018 hmeg3_RS21255 6b08cf1dcf340c39ed6790ef1dafe222 408 Gene3D G3DSA:3.40.50.150 55 256 1.3E-24 T 28-03-2018 hmeg3_RS21255 6b08cf1dcf340c39ed6790ef1dafe222 408 SUPERFAMILY SSF53335 56 252 1.85E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase hmeg3_RS21255 6b08cf1dcf340c39ed6790ef1dafe222 408 Pfam PF08421 Putative zinc binding domain 3 64 4.0E-22 T 28-03-2018 IPR013630 Methyltransferase putative zinc binding domain hmeg3_RS23810 939e7bf6ff52ba64e484c08f06e22c2d 137 SUPERFAMILY SSF160424 69 109 6.67E-6 T 28-03-2018 IPR006728 Protein of unknown function DUF600 hmeg3_RS00665 15b126d7dec246bd1fc8f47e7763aeb2 299 SUPERFAMILY SSF51197 19 299 5.49E-87 T 28-03-2018 hmeg3_RS00665 15b126d7dec246bd1fc8f47e7763aeb2 299 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 22 292 8.1E-66 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS00665 15b126d7dec246bd1fc8f47e7763aeb2 299 Gene3D G3DSA:3.60.130.10 15 299 3.5E-71 T 28-03-2018 hmeg3_RS24185 ae594149450d96af7d652e89648ac10b 257 Pfam PF01925 Sulfite exporter TauE/SafE 13 249 6.5E-40 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS06650 5e204b34acbcd7328dda233ca357a385 149 Gene3D G3DSA:2.70.40.10 111 148 4.3E-14 T 28-03-2018 hmeg3_RS06650 5e204b34acbcd7328dda233ca357a385 149 Pfam PF00692 dUTPase 15 147 2.0E-36 T 28-03-2018 IPR029054 dUTPase-like hmeg3_RS06650 5e204b34acbcd7328dda233ca357a385 149 SUPERFAMILY SSF51283 3 148 1.7E-50 T 28-03-2018 IPR029054 dUTPase-like hmeg3_RS06650 5e204b34acbcd7328dda233ca357a385 149 Gene3D G3DSA:2.70.40.10 1 110 6.3E-37 T 28-03-2018 hmeg3_RS06650 5e204b34acbcd7328dda233ca357a385 149 TIGRFAM TIGR00576 dut: dUTP diphosphatase 12 148 1.3E-47 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 hmeg3_RS06650 5e204b34acbcd7328dda233ca357a385 149 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 148 33.344 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 hmeg3_RS12280 d297ec43e6da18d3b50632e0c5e72d6b 139 SUPERFAMILY SSF51182 40 125 3.85E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS12280 d297ec43e6da18d3b50632e0c5e72d6b 139 Gene3D G3DSA:2.60.120.10 11 139 2.8E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS12280 d297ec43e6da18d3b50632e0c5e72d6b 139 Pfam PF07883 Cupin domain 54 124 2.8E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS13000 c17e91e4bf587b9ed99202d3272c8f4a 446 SUPERFAMILY SSF116734 227 440 2.62E-31 T 28-03-2018 hmeg3_RS13000 c17e91e4bf587b9ed99202d3272c8f4a 446 Pfam PF01420 Type I restriction modification DNA specificity domain 241 385 2.5E-11 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 hmeg3_RS13000 c17e91e4bf587b9ed99202d3272c8f4a 446 Pfam PF01420 Type I restriction modification DNA specificity domain 76 191 1.1E-9 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 hmeg3_RS13000 c17e91e4bf587b9ed99202d3272c8f4a 446 SUPERFAMILY SSF116734 2 208 2.13E-29 T 28-03-2018 hmeg3_RS13000 c17e91e4bf587b9ed99202d3272c8f4a 446 Gene3D G3DSA:3.90.220.20 1 185 1.7E-22 T 28-03-2018 hmeg3_RS13000 c17e91e4bf587b9ed99202d3272c8f4a 446 Gene3D G3DSA:3.90.220.20 186 416 5.0E-25 T 28-03-2018 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 ProSitePatterns PS00146 Beta-lactamase class-A active site. 75 90 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 SUPERFAMILY SSF56601 38 295 8.15E-80 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 Pfam PF13354 Beta-lactamase enzyme family 63 269 2.5E-45 T 28-03-2018 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 Gene3D G3DSA:3.40.710.10 40 296 1.5E-36 T 28-03-2018 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 116 141 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 73 90 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 178 203 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 214 229 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 42 66 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 152 176 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS07395 dcf4b2de90fbcc59dfdbc6c654df7101 299 PRINTS PR00118 Beta-lactamase class A signature 231 246 1.8E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 hmeg3_RS04645 cfe6f77548eb4b7745b1ad9c3153a26a 316 SUPERFAMILY SSF52283 7 137 7.37E-33 T 28-03-2018 hmeg3_RS04645 cfe6f77548eb4b7745b1ad9c3153a26a 316 Gene3D G3DSA:3.40.50.720 7 116 2.2E-29 T 28-03-2018 hmeg3_RS04645 cfe6f77548eb4b7745b1ad9c3153a26a 316 Gene3D G3DSA:3.40.50.720 117 286 5.7E-55 T 28-03-2018 hmeg3_RS04645 cfe6f77548eb4b7745b1ad9c3153a26a 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 283 1.5E-55 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 hmeg3_RS04645 cfe6f77548eb4b7745b1ad9c3153a26a 316 SUPERFAMILY SSF51735 103 284 1.38E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS04645 cfe6f77548eb4b7745b1ad9c3153a26a 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 314 4.1E-27 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 hmeg3_RS08690 84e7e57d38954310cb3a32269a339307 310 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 14 65 7.0E-18 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain hmeg3_RS08690 84e7e57d38954310cb3a32269a339307 310 SUPERFAMILY SSF103088 168 274 1.31E-18 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS08690 84e7e57d38954310cb3a32269a339307 310 Gene3D G3DSA:3.30.1330.60 117 302 4.5E-37 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS08690 84e7e57d38954310cb3a32269a339307 310 Pfam PF00691 OmpA family 170 253 1.9E-12 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS16710 2a6f9d95984f1954cde3117e13f45ba8 222 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 8 84 2.6E-15 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 hmeg3_RS16710 2a6f9d95984f1954cde3117e13f45ba8 222 SUPERFAMILY SSF89069 7 74 2.62E-12 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 hmeg3_RS06890 2c451a0c7115769c65fd16a7f7c87c2f 117 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 17 112 20.133 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 hmeg3_RS06890 2c451a0c7115769c65fd16a7f7c87c2f 117 Gene3D G3DSA:3.30.1360.20 11 115 1.3E-25 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 hmeg3_RS06890 2c451a0c7115769c65fd16a7f7c87c2f 117 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 19 110 8.6E-26 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 hmeg3_RS06890 2c451a0c7115769c65fd16a7f7c87c2f 117 SUPERFAMILY SSF55248 18 113 1.7E-25 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 15 310 2.3E-104 T 28-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 207 228 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 294 312 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 9 29 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 251 272 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 31 54 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 56 76 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 PRINTS PR01002 Flagellar protein FlgJ signature 229 250 5.5E-44 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 Gene3D G3DSA:1.10.530.10 158 312 9.4E-35 T 28-03-2018 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 175 310 9.2E-22 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 Pfam PF10135 Rod binding protein 53 99 1.1E-19 T 28-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal hmeg3_RS08230 7e4bc52a3c73deb055cd4a576877eba3 314 SMART SM00047 158 313 2.6E-35 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 hmeg3_RS17155 d76267c70872087ca1dc37afa8c5fcf9 291 Hamap MF_00188 Protease HtpX [htpX]. 1 290 25.901 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 hmeg3_RS17155 d76267c70872087ca1dc37afa8c5fcf9 291 Gene3D G3DSA:3.30.2010.10 70 162 1.8E-19 T 28-03-2018 hmeg3_RS17155 d76267c70872087ca1dc37afa8c5fcf9 291 Pfam PF01435 Peptidase family M48 80 289 1.3E-38 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 hmeg3_RS07925 0bcb270ff9c35ff36862733452ad1c4e 253 Pfam PF11736 Protein of unknown function (DUF3299) 105 245 3.1E-43 T 28-03-2018 IPR021727 Protein of unknown function DUF3299 hmeg3_RS17490 1beab3d6faf83007f4f27d08b499edab 497 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 438 1.9E-130 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane hmeg3_RS09620 e84da5d5d4f23efdfba9c189bbe8cad8 337 Pfam PF14022 Protein of unknown function (DUF4238) 10 292 4.3E-28 T 28-03-2018 IPR025332 Protein of unknown function DUF4238 hmeg3_RS00920 98d33d69b0ea372931740d61f0a0ded3 492 Gene3D G3DSA:1.20.1600.10 29 492 2.3E-85 T 28-03-2018 hmeg3_RS00920 98d33d69b0ea372931740d61f0a0ded3 492 SUPERFAMILY SSF56954 15 38 5.49E-96 T 28-03-2018 hmeg3_RS00920 98d33d69b0ea372931740d61f0a0ded3 492 SUPERFAMILY SSF56954 70 492 5.49E-96 T 28-03-2018 hmeg3_RS00920 98d33d69b0ea372931740d61f0a0ded3 492 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 491 3.0E-88 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 hmeg3_RS00920 98d33d69b0ea372931740d61f0a0ded3 492 Pfam PF02321 Outer membrane efflux protein 310 476 1.9E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS00920 98d33d69b0ea372931740d61f0a0ded3 492 Pfam PF02321 Outer membrane efflux protein 79 275 3.4E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 hmeg3_RS13035 2857b392b312a9e1d10c267210817939 62 Pfam PF06945 Protein of unknown function (DUF1289) 7 48 3.1E-14 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 hmeg3_RS22470 727575167240bbcbde576bc309128124 156 Gene3D G3DSA:3.30.700.10 26 152 3.7E-22 T 28-03-2018 hmeg3_RS22470 727575167240bbcbde576bc309128124 156 SUPERFAMILY SSF54523 52 148 3.92E-29 T 28-03-2018 hmeg3_RS22470 727575167240bbcbde576bc309128124 156 Pfam PF08334 Type II secretion system (T2SS), protein G 47 153 7.2E-29 T 28-03-2018 IPR013545 Type II secretion system protein G hmeg3_RS22470 727575167240bbcbde576bc309128124 156 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 19 148 2.0E-32 T 28-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 hmeg3_RS01000 9b925fef1ac6e848beda11a1248e38ed 395 Pfam PF01734 Patatin-like phospholipase 12 266 2.5E-8 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 hmeg3_RS01000 9b925fef1ac6e848beda11a1248e38ed 395 SUPERFAMILY SSF52151 178 376 3.98E-23 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS01000 9b925fef1ac6e848beda11a1248e38ed 395 SUPERFAMILY SSF52151 8 82 3.98E-23 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 hmeg3_RS01000 9b925fef1ac6e848beda11a1248e38ed 395 Gene3D G3DSA:3.40.1090.10 1 387 6.2E-19 T 28-03-2018 hmeg3_RS03430 e71ea3852ac49fff4d9cd95618671e70 259 Pfam PF02405 Permease MlaE 45 256 7.5E-75 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 hmeg3_RS03430 e71ea3852ac49fff4d9cd95618671e70 259 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 6 258 2.3E-84 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria hmeg3_RS06715 8fe8b66b5409082d7ed11108c50fd472 126 Pfam PF11533 Protein of unknown function (DUF3225) 4 125 3.5E-55 T 28-03-2018 IPR024507 Protein of unknown function DUF3225 hmeg3_RS06715 8fe8b66b5409082d7ed11108c50fd472 126 SUPERFAMILY SSF54427 5 125 5.61E-34 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS06715 8fe8b66b5409082d7ed11108c50fd472 126 Gene3D G3DSA:3.10.450.50 3 126 6.9E-19 T 28-03-2018 hmeg3_RS09830 b26933e8b3c1be2324a04e0649298f3c 218 SUPERFAMILY SSF161098 12 199 9.29E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS09830 b26933e8b3c1be2324a04e0649298f3c 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 108 2.7E-31 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS09830 b26933e8b3c1be2324a04e0649298f3c 218 Gene3D G3DSA:1.10.3720.10 3 218 2.7E-41 T 28-03-2018 hmeg3_RS09830 b26933e8b3c1be2324a04e0649298f3c 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 213 1.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17095 bfc44da1df0361ea07026603bd9fb718 392 Gene3D G3DSA:3.40.50.2300 34 201 3.8E-17 T 28-03-2018 hmeg3_RS17095 bfc44da1df0361ea07026603bd9fb718 392 Gene3D G3DSA:3.40.50.2300 202 367 2.4E-23 T 28-03-2018 hmeg3_RS17095 bfc44da1df0361ea07026603bd9fb718 392 SUPERFAMILY SSF53822 37 380 2.38E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS17095 bfc44da1df0361ea07026603bd9fb718 392 Pfam PF13458 Periplasmic binding protein 42 370 5.4E-41 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS16400 3db1543bc50115fd9b0b892e089e3557 197 Pfam PF02361 Cobalt transport protein 9 195 1.9E-11 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component hmeg3_RS08290 66fff5ec2a32f90e307a04971ea838c7 173 Pfam PF03748 Flagellar basal body-associated protein FliL 71 171 2.9E-24 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 hmeg3_RS02795 d1c989a8c9237087732964c298dea2f1 356 Pfam PF04892 VanZ like family 11 113 3.5E-9 T 28-03-2018 IPR006976 VanZ-like hmeg3_RS23140 293edf3d71c856b11ad1b9d56c3bb40e 181 Gene3D G3DSA:1.20.1290.10 42 179 1.9E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS23140 293edf3d71c856b11ad1b9d56c3bb40e 181 SUPERFAMILY SSF69118 14 175 6.4E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS23140 293edf3d71c856b11ad1b9d56c3bb40e 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 57 114 1.9E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS23140 293edf3d71c856b11ad1b9d56c3bb40e 181 Gene3D G3DSA:1.20.5.810 12 41 6.6E-5 T 28-03-2018 hmeg3_RS12455 0d8b130dded85a6435c7d08d3d22c577 69 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 26 69 4.1E-19 T 28-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative hmeg3_RS12455 0d8b130dded85a6435c7d08d3d22c577 69 TIGRFAM TIGR02459 CbtB: cobalt transporter subunit CbtB (proposed) 17 69 1.4E-19 T 28-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 SMART SM00342 202 285 9.7E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 Pfam PF12833 Helix-turn-helix domain 208 281 3.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 Pfam PF06719 AraC-type transcriptional regulator N-terminus 25 173 2.1E-40 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 SUPERFAMILY SSF46689 238 284 1.3E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 Gene3D G3DSA:1.10.10.60 182 240 3.8E-14 T 28-03-2018 hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 Gene3D G3DSA:1.10.10.60 241 293 2.1E-8 T 28-03-2018 hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 SUPERFAMILY SSF46689 186 236 5.2E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 hmeg3_RS14430 70e5c2219d93b186e1d3f015a3edf401 296 Gene3D G3DSA:2.60.120.10 26 93 3.3E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 4.1E-16 T 28-03-2018 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.1E-16 T 28-03-2018 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 4.1E-16 T 28-03-2018 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 4.1E-16 T 28-03-2018 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 Gene3D G3DSA:3.50.50.60 2 355 1.5E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 SUPERFAMILY SSF54373 175 276 4.71E-11 T 28-03-2018 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 Pfam PF01494 FAD binding domain 6 345 1.1E-26 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 SUPERFAMILY SSF51905 272 371 7.38E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS00150 2be22e61143f35067a57b1583ac5f681 385 SUPERFAMILY SSF51905 4 171 7.38E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS07715 8e76a08e7fc48ce8b6d1f86173246aae 102 SUPERFAMILY SSF143120 1 80 8.11E-22 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM hmeg3_RS07715 8e76a08e7fc48ce8b6d1f86173246aae 102 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 55 1.1E-6 T 28-03-2018 hmeg3_RS07715 8e76a08e7fc48ce8b6d1f86173246aae 102 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 74 3.0E-20 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM hmeg3_RS07715 8e76a08e7fc48ce8b6d1f86173246aae 102 Gene3D G3DSA:3.40.1620.10 1 40 1.6E-13 T 28-03-2018 hmeg3_RS15215 8dcb1c60fa5a480504b82244984adf2c 280 Gene3D G3DSA:1.20.1260.10 126 209 0.0048 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS15215 8dcb1c60fa5a480504b82244984adf2c 280 Pfam PF10118 Predicted metal-dependent hydrolase 10 259 2.9E-71 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 hmeg3_RS15215 8dcb1c60fa5a480504b82244984adf2c 280 Gene3D G3DSA:1.20.1260.10 10 118 0.18 T 28-03-2018 IPR012347 Ferritin-related hmeg3_RS15215 8dcb1c60fa5a480504b82244984adf2c 280 PIRSF PIRSF007580 1 277 1.4E-60 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 hmeg3_RS17190 57532d274bdf99bb7932cc85133fdb66 162 Pfam PF02674 Colicin V production protein 4 144 1.5E-37 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 hmeg3_RS18680 38df2658833a818802a9606c350e8f8a 290 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 72 276 7.8E-14 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS18680 38df2658833a818802a9606c350e8f8a 290 SUPERFAMILY SSF53850 51 277 9.19E-31 T 28-03-2018 hmeg3_RS18680 38df2658833a818802a9606c350e8f8a 290 Gene3D G3DSA:3.40.190.10 53 278 2.4E-13 T 28-03-2018 hmeg3_RS08685 239cc8af4c0f2f57a573b816b41b751d 286 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site hmeg3_RS08685 239cc8af4c0f2f57a573b816b41b751d 286 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 236 2.0E-9 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 hmeg3_RS08685 239cc8af4c0f2f57a573b816b41b751d 286 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 282 3.9E-122 T 28-03-2018 IPR022522 Flagellar motor stator, MotA hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 Gene3D G3DSA:1.10.760.10 67 193 1.6E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 84 156 1.3E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 SUPERFAMILY SSF46626 76 164 7.9E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 PRINTS PR00607 Class IE cytochrome C signature 131 143 6.3E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 PRINTS PR00607 Class IE cytochrome C signature 146 157 6.3E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 PRINTS PR00607 Class IE cytochrome C signature 103 113 6.3E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02070 7d5b6a610c7e1e4a5d8d5f03efb9538c 194 PRINTS PR00607 Class IE cytochrome C signature 92 103 6.3E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 hmeg3_RS12200 c0470720e38f9f05b7003ecf10133b9e 351 Pfam PF00487 Fatty acid desaturase 50 304 2.7E-32 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 hmeg3_RS14520 6b7154c3bc66883cc0ee9d8e42420b83 286 SUPERFAMILY SSF103481 180 285 1.96E-12 T 28-03-2018 hmeg3_RS14520 6b7154c3bc66883cc0ee9d8e42420b83 286 Pfam PF00892 EamA-like transporter family 146 284 1.7E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS14520 6b7154c3bc66883cc0ee9d8e42420b83 286 Pfam PF00892 EamA-like transporter family 7 133 4.7E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS14520 6b7154c3bc66883cc0ee9d8e42420b83 286 SUPERFAMILY SSF103481 36 134 2.48E-11 T 28-03-2018 hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 362 38.653 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 Gene3D G3DSA:2.40.30.10 285 364 1.6E-25 T 28-03-2018 hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 SUPERFAMILY SSF52402 3 242 1.06E-54 T 28-03-2018 hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 Gene3D G3DSA:2.30.30.280 211 283 8.5E-25 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 Gene3D G3DSA:3.40.50.620 1 210 1.4E-61 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 4 361 7.4E-129 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 hmeg3_RS19960 7beef72be4e21ea6717bde20cf8fe94d 364 Pfam PF03054 tRNA methyl transferase 4 361 4.3E-131 T 28-03-2018 hmeg3_RS19825 93d61c35e67d505fc8d8f5029f9132b1 203 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 168 190 3.8E-6 T 28-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 hmeg3_RS19825 93d61c35e67d505fc8d8f5029f9132b1 203 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 16 39 3.8E-6 T 28-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 hmeg3_RS19825 93d61c35e67d505fc8d8f5029f9132b1 203 SUPERFAMILY SSF81342 12 203 3.3E-37 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 hmeg3_RS19825 93d61c35e67d505fc8d8f5029f9132b1 203 Gene3D G3DSA:1.20.950.20 9 203 6.2E-37 T 28-03-2018 hmeg3_RS19825 93d61c35e67d505fc8d8f5029f9132b1 203 Pfam PF01292 Prokaryotic cytochrome b561 13 202 6.8E-28 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 hmeg3_RS15655 6103c6142239dc2cf32cfbf4d0ba3cd2 437 SUPERFAMILY SSF51905 38 263 2.56E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS15655 6103c6142239dc2cf32cfbf4d0ba3cd2 437 SUPERFAMILY SSF51905 355 401 2.56E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS15655 6103c6142239dc2cf32cfbf4d0ba3cd2 437 Pfam PF01266 FAD dependent oxidoreductase 39 392 3.7E-62 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 hmeg3_RS15655 6103c6142239dc2cf32cfbf4d0ba3cd2 437 Gene3D G3DSA:3.50.50.60 26 404 3.1E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS03440 d3dba8f7af5e0796fe783e3e5e732843 237 PRINTS PR01805 VacJ lipoprotein signature 131 148 1.5E-28 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 hmeg3_RS03440 d3dba8f7af5e0796fe783e3e5e732843 237 PRINTS PR01805 VacJ lipoprotein signature 44 60 1.5E-28 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 hmeg3_RS03440 d3dba8f7af5e0796fe783e3e5e732843 237 PRINTS PR01805 VacJ lipoprotein signature 27 40 1.5E-28 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 hmeg3_RS03440 d3dba8f7af5e0796fe783e3e5e732843 237 PRINTS PR01805 VacJ lipoprotein signature 95 112 1.5E-28 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 hmeg3_RS03440 d3dba8f7af5e0796fe783e3e5e732843 237 Pfam PF04333 MlaA lipoprotein 26 218 6.4E-75 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 hmeg3_RS24470 deb10a77b79c891618c230f6c9d3665a 97 Pfam PF12365 Protein of unknown function (DUF3649) 65 89 2.9E-9 T 28-03-2018 IPR022109 Protein of unknown function DUF3649 hmeg3_RS16205 ba5d4716c18d21f76bd1c600ceb1da18 260 SUPERFAMILY SSF53448 6 239 2.25E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS16205 ba5d4716c18d21f76bd1c600ceb1da18 260 Pfam PF00535 Glycosyl transferase family 2 12 134 5.0E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS16205 ba5d4716c18d21f76bd1c600ceb1da18 260 Gene3D G3DSA:3.90.550.10 2 239 3.5E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 PIRSF PIRSF001434 1 431 9.6E-131 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 Gene3D G3DSA:3.40.640.10 9 295 5.2E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 10 428 1.3E-201 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 428 6.8E-146 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 Gene3D G3DSA:3.90.1150.10 297 431 1.1E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 hmeg3_RS09505 ffb3d89ab563f58440a0dabbb826355e 431 SUPERFAMILY SSF53383 9 428 7.05E-132 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 SUPERFAMILY SSF46626 26 101 6.3E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 Pfam PF00034 Cytochrome c 23 101 1.6E-4 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 Gene3D G3DSA:1.10.760.10 23 102 4.6E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 PRINTS PR00606 Class ID cytochrome C signature 27 40 1.4E-19 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 PRINTS PR00606 Class ID cytochrome C signature 80 90 1.4E-19 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 PRINTS PR00606 Class ID cytochrome C signature 92 102 1.4E-19 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 PRINTS PR00606 Class ID cytochrome C signature 42 55 1.4E-19 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS02270 4b497291295990189c4395b74a3c3732 105 PRINTS PR00606 Class ID cytochrome C signature 65 78 1.4E-19 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 hmeg3_RS07845 4ea768b569cf4b86663ce837a39f83ec 308 Pfam PF00535 Glycosyl transferase family 2 8 168 9.5E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 hmeg3_RS07845 4ea768b569cf4b86663ce837a39f83ec 308 SUPERFAMILY SSF53448 4 232 2.25E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS07845 4ea768b569cf4b86663ce837a39f83ec 308 Gene3D G3DSA:3.90.550.10 2 266 6.2E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases hmeg3_RS04765 86b736d8576eb91113e31f668886151e 184 SUPERFAMILY SSF50341 43 180 5.1E-21 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS04765 86b736d8576eb91113e31f668886151e 184 Gene3D G3DSA:2.40.50.180 61 148 3.7E-16 T 28-03-2018 hmeg3_RS04765 86b736d8576eb91113e31f668886151e 184 SMART SM00260 34 174 2.5E-4 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS04765 86b736d8576eb91113e31f668886151e 184 Pfam PF01584 CheW-like domain 45 158 7.5E-18 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 Gene3D G3DSA:2.40.50.140 32 123 5.4E-29 T 28-03-2018 hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 7.8E-159 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 SMART SM00316 37 118 8.8E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 SUPERFAMILY SSF50249 40 124 8.04E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 Pfam PF10150 Ribonuclease E/G family 120 389 1.4E-91 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 Hamap MF_00970 Ribonuclease E [rne]. 1 1026 34.873 T 28-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 hmeg3_RS09095 b7692b8b98403201711acf7f851c5859 1038 Pfam PF00575 S1 RNA binding domain 36 116 2.3E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 hmeg3_RS13140 136f06860dc3afad2f45db067bb57e96 255 Pfam PF09836 Putative DNA-binding domain 8 95 2.0E-19 T 28-03-2018 IPR018640 Putative DNA-binding domain, bacteria hmeg3_RS09395 75052a63ac5a811c9d8b32ba223362a7 446 Pfam PF12801 4Fe-4S binding domain 50 90 5.9E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS09395 75052a63ac5a811c9d8b32ba223362a7 446 Pfam PF12801 4Fe-4S binding domain 147 168 5.1E-4 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain hmeg3_RS00025 bb94be968856b58654f4ff452e002205 344 SMART SM01150 45 337 4.2E-80 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 hmeg3_RS00025 bb94be968856b58654f4ff452e002205 344 Pfam PF07063 Domain of unknown function (DUF1338) 43 336 1.4E-64 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 hmeg3_RS00110 d690bf528494b13b09012a8588a22890 179 SUPERFAMILY SSF51182 13 173 4.46E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS00110 d690bf528494b13b09012a8588a22890 179 Gene3D G3DSA:2.60.120.10 26 174 2.0E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS00110 d690bf528494b13b09012a8588a22890 179 Pfam PF07883 Cupin domain 84 153 1.3E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS20110 a2ca9a1f09ba022ac6467671d7332d94 143 Pfam PF13474 SnoaL-like domain 16 128 5.9E-22 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS20110 a2ca9a1f09ba022ac6467671d7332d94 143 Gene3D G3DSA:3.10.450.50 8 131 3.2E-23 T 28-03-2018 hmeg3_RS20110 a2ca9a1f09ba022ac6467671d7332d94 143 SUPERFAMILY SSF54427 11 128 4.39E-30 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS15890 fcc613610749a77bd59bcf464a0b4d9b 207 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 200 78.032 T 28-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria hmeg3_RS15890 fcc613610749a77bd59bcf464a0b4d9b 207 Pfam PF03350 Uncharacterized protein family, UPF0114 21 159 7.2E-42 T 28-03-2018 IPR005134 Uncharacterised protein family UPF0114 hmeg3_RS07345 6f9cddc05be7133e50274127b3ce98d0 196 SUPERFAMILY SSF54211 4 127 1.63E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold hmeg3_RS07345 6f9cddc05be7133e50274127b3ce98d0 196 SUPERFAMILY SSF54980 131 186 1.44E-6 T 28-03-2018 IPR035647 EF-G domain III/V-like hmeg3_RS07345 6f9cddc05be7133e50274127b3ce98d0 196 Gene3D G3DSA:3.30.70.240 130 190 2.0E-11 T 28-03-2018 hmeg3_RS07345 6f9cddc05be7133e50274127b3ce98d0 196 Pfam PF01205 Uncharacterized protein family UPF0029 17 119 9.2E-29 T 28-03-2018 IPR001498 Impact, N-terminal hmeg3_RS07345 6f9cddc05be7133e50274127b3ce98d0 196 Pfam PF09186 Domain of unknown function (DUF1949) 135 183 6.2E-10 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal hmeg3_RS07345 6f9cddc05be7133e50274127b3ce98d0 196 Gene3D G3DSA:3.30.230.30 2 128 7.2E-41 T 28-03-2018 IPR001498 Impact, N-terminal hmeg3_RS23945 8392f55a90d33a792d634c3122987d57 133 SUPERFAMILY SSF69118 1 129 1.16E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS23945 8392f55a90d33a792d634c3122987d57 133 Gene3D G3DSA:1.20.1290.10 45 126 1.3E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS23945 8392f55a90d33a792d634c3122987d57 133 Gene3D G3DSA:1.20.5.810 11 44 4.0E-13 T 28-03-2018 hmeg3_RS23945 8392f55a90d33a792d634c3122987d57 133 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 122 3.6E-18 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS23945 8392f55a90d33a792d634c3122987d57 133 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 107 5.2E-16 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 hmeg3_RS11115 75da91ed0f71677c6c9bed6140930dc1 173 Gene3D G3DSA:1.20.1290.10 24 172 2.6E-12 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS11115 75da91ed0f71677c6c9bed6140930dc1 173 SUPERFAMILY SSF69118 25 166 2.13E-18 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 hmeg3_RS11115 75da91ed0f71677c6c9bed6140930dc1 173 TIGRFAM TIGR04029 CMD_Avi_7170: CMD domain protein, Avi_7170 family 12 167 1.1E-29 T 28-03-2018 IPR023982 Conserved hypothetical protein CHP04029, CMD-like hmeg3_RS19990 dac83e0e10225a4b27c29cb5fa70068a 138 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 135 1.8E-30 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 hmeg3_RS16785 e9b42b14639d844604e3bf53ed5ec751 141 SMART SM00347 31 134 1.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 hmeg3_RS16785 e9b42b14639d844604e3bf53ed5ec751 141 SUPERFAMILY SSF46785 11 133 8.24E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS16785 e9b42b14639d844604e3bf53ed5ec751 141 Pfam PF12802 MarR family 37 97 1.7E-12 T 28-03-2018 hmeg3_RS16785 e9b42b14639d844604e3bf53ed5ec751 141 Gene3D G3DSA:1.10.10.10 8 131 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 57 7.2E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 Gene3D G3DSA:1.10.150.120 73 147 1.8E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 Pfam PF01799 [2Fe-2S] binding domain 71 141 7.0E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 SUPERFAMILY SSF54292 2 76 1.97E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 SUPERFAMILY SSF47741 71 146 9.03E-30 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 hmeg3_RS01055 0fc728edbed4127ad1d3b11dfe328811 147 Gene3D G3DSA:3.10.20.30 1 72 5.9E-26 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS12195 c155389cb17470ce31c7a1015e9f12e7 204 SUPERFAMILY SSF56925 23 204 4.97E-29 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS12195 c155389cb17470ce31c7a1015e9f12e7 204 Gene3D G3DSA:2.40.160.20 22 204 1.6E-30 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS12195 c155389cb17470ce31c7a1015e9f12e7 204 Pfam PF03922 OmpW family 23 204 4.7E-45 T 28-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 hmeg3_RS11570 ba7604f30694ce57017655ec6256adf1 235 Pfam PF01988 VIT family 21 228 2.9E-53 T 28-03-2018 IPR008217 Ccc1 family hmeg3_RS05885 1b5e6e776133060b9e5f4d7b844a6d66 76 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 59 3.0E-16 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor hmeg3_RS05885 1b5e6e776133060b9e5f4d7b844a6d66 76 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 2 67 1.9E-30 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor hmeg3_RS07430 807deed6b4d0df47f53b75e95c2f1448 202 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 2.0E-9 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 hmeg3_RS07430 807deed6b4d0df47f53b75e95c2f1448 202 SUPERFAMILY SSF52833 1 78 2.15E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS07430 807deed6b4d0df47f53b75e95c2f1448 202 Gene3D G3DSA:1.20.1050.10 91 201 3.7E-23 T 28-03-2018 hmeg3_RS07430 807deed6b4d0df47f53b75e95c2f1448 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 103 189 1.9E-14 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal hmeg3_RS07430 807deed6b4d0df47f53b75e95c2f1448 202 SUPERFAMILY SSF47616 82 197 1.39E-27 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like hmeg3_RS07430 807deed6b4d0df47f53b75e95c2f1448 202 Gene3D G3DSA:3.40.30.10 1 90 1.3E-18 T 28-03-2018 hmeg3_RS05065 6ff558ad10bfbdc5e93a7eb548e1fccc 110 Pfam PF02699 Preprotein translocase subunit 24 99 2.1E-31 T 28-03-2018 IPR003849 Preprotein translocase YajC hmeg3_RS05065 6ff558ad10bfbdc5e93a7eb548e1fccc 110 SMART SM01323 20 102 9.7E-47 T 28-03-2018 IPR003849 Preprotein translocase YajC hmeg3_RS05065 6ff558ad10bfbdc5e93a7eb548e1fccc 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 102 2.7E-29 T 28-03-2018 IPR003849 Preprotein translocase YajC hmeg3_RS05065 6ff558ad10bfbdc5e93a7eb548e1fccc 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 8.8E-18 T 28-03-2018 IPR003849 Preprotein translocase YajC hmeg3_RS05065 6ff558ad10bfbdc5e93a7eb548e1fccc 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 8.8E-18 T 28-03-2018 IPR003849 Preprotein translocase YajC hmeg3_RS13125 14038320ae58090986309161e0320dd9 395 Pfam PF06224 Winged helix DNA-binding domain 41 381 4.8E-64 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 Gene3D G3DSA:3.30.870.10 2 199 5.2E-32 T 28-03-2018 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 Gene3D G3DSA:3.30.870.10 201 363 4.0E-28 T 28-03-2018 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 Hamap MF_01917 Cardiolipin synthase B [clsB]. 3 386 39.27 T 28-03-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 Pfam PF13091 PLD-like domain 218 340 1.9E-23 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 Pfam PF13091 PLD-like domain 25 129 2.8E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 SUPERFAMILY SSF56024 6 187 6.06E-38 T 28-03-2018 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 SMART SM00155 104 131 5.6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 SMART SM00155 289 316 0.0094 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 hmeg3_RS22380 99ecd2aeb6e021f10769bff5d9903f86 386 SUPERFAMILY SSF56024 194 362 5.16E-33 T 28-03-2018 hmeg3_RS20270 9cbe00f0a4ac51466e9065af0896c77d 294 PIRSF PIRSF009120 1 249 2.4E-110 T 28-03-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 hmeg3_RS20270 9cbe00f0a4ac51466e9065af0896c77d 294 Gene3D G3DSA:3.60.20.10 2 231 1.1E-37 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS20270 9cbe00f0a4ac51466e9065af0896c77d 294 SUPERFAMILY SSF56235 2 241 1.61E-33 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS16565 4764c03e7ca942b82d4d35a22b289d2e 203 Pfam PF10001 Uncharacterized protein conserved in bacteria (DUF2242) 55 175 2.9E-54 T 28-03-2018 IPR018718 Protein of unknown function DUF2242 hmeg3_RS04230 d456367c6c796973f1b9119f608ac121 191 Pfam PF01169 Uncharacterized protein family UPF0016 104 178 5.5E-23 T 28-03-2018 IPR001727 Gdt1 family hmeg3_RS04230 d456367c6c796973f1b9119f608ac121 191 Pfam PF01169 Uncharacterized protein family UPF0016 6 80 3.3E-19 T 28-03-2018 IPR001727 Gdt1 family hmeg3_RS04230 d456367c6c796973f1b9119f608ac121 191 Gene3D G3DSA:1.20.1250.20 96 189 0.11 T 28-03-2018 hmeg3_RS19975 24283961186094315d0e51946947de34 75 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 6.6E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain hmeg3_RS23760 a24756bedbb4d91c1fb373b7e1bee443 333 Pfam PF00144 Beta-lactamase 15 304 7.9E-48 T 28-03-2018 IPR001466 Beta-lactamase-related hmeg3_RS23760 a24756bedbb4d91c1fb373b7e1bee443 333 SUPERFAMILY SSF56601 6 316 5.96E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS23760 a24756bedbb4d91c1fb373b7e1bee443 333 Gene3D G3DSA:3.40.710.10 3 307 5.4E-66 T 28-03-2018 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 Pfam PF07687 Peptidase dimerisation domain 190 285 2.5E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 377 6.0E-107 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 Gene3D G3DSA:3.40.630.10 8 252 1.2E-51 T 28-03-2018 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 Gene3D G3DSA:3.40.630.10 253 394 7.7E-21 T 28-03-2018 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 Pfam PF01546 Peptidase family M20/M25/M40 76 388 2.7E-35 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 SUPERFAMILY SSF55031 189 300 3.66E-30 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 SUPERFAMILY SSF53187 10 201 1.57E-86 T 28-03-2018 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 SUPERFAMILY SSF53187 302 391 1.57E-86 T 28-03-2018 hmeg3_RS03800 6ca0ab9acee736e44f3d64ef1b0f402d 394 PIRSF PIRSF005962 6 393 4.5E-125 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 hmeg3_RS16445 46d9430aaf70b4eee3cb2ae0bb7054d8 71 Pfam PF05433 Glycine zipper 2TM domain 33 70 1.3E-6 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 hmeg3_RS18990 55e021f36bed4e16b2cf31e021ba2a65 582 SUPERFAMILY SSF143975 4 379 1.26E-123 T 28-03-2018 hmeg3_RS18990 55e021f36bed4e16b2cf31e021ba2a65 582 Pfam PF00920 Dehydratase family 42 564 4.0E-173 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS18990 55e021f36bed4e16b2cf31e021ba2a65 582 SUPERFAMILY SSF52016 380 569 2.75E-54 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel hmeg3_RS18990 55e021f36bed4e16b2cf31e021ba2a65 582 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 Gene3D G3DSA:3.40.190.10 186 269 4.1E-17 T 28-03-2018 hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 Gene3D G3DSA:1.10.10.10 1 88 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 Pfam PF03466 LysR substrate binding domain 101 295 1.3E-32 T 28-03-2018 IPR005119 LysR, substrate-binding hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 2.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 Gene3D G3DSA:3.40.190.10 101 185 1.5E-16 T 28-03-2018 hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 SUPERFAMILY SSF53850 91 295 2.17E-42 T 28-03-2018 hmeg3_RS23200 0aa012b37b7ebd1f52b11798fda7cadd 297 SUPERFAMILY SSF46785 4 85 3.98E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07330 fc1ec870908b804efdeec59214686463 220 Gene3D G3DSA:1.10.10.10 2 161 3.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS07330 fc1ec870908b804efdeec59214686463 220 SUPERFAMILY SSF46785 15 197 1.49E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS24235 4e47e5f03e63c8cf6f98c411113d5c1b 102 SUPERFAMILY SSF54292 6 97 1.84E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS24235 4e47e5f03e63c8cf6f98c411113d5c1b 102 Gene3D G3DSA:3.10.20.30 1 102 2.9E-19 T 28-03-2018 IPR012675 Beta-grasp domain hmeg3_RS24235 4e47e5f03e63c8cf6f98c411113d5c1b 102 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 87 6.3E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 hmeg3_RS19835 aed4350f43983d21d320083bbad839ba 84 TIGRFAM TIGR02953 penta_MxKDx: pentapeptide MXKDX repeat protein 7 77 7.4E-16 T 28-03-2018 IPR014299 Pentapeptide MXKDX repeat protein hmeg3_RS20505 f6c02a742f1b9f10939a0c62aa48553e 201 SUPERFAMILY SSF52833 6 200 1.23E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS20505 f6c02a742f1b9f10939a0c62aa48553e 201 Pfam PF01323 DSBA-like thioredoxin domain 7 198 1.1E-35 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 hmeg3_RS20505 f6c02a742f1b9f10939a0c62aa48553e 201 PIRSF PIRSF006386 1 201 1.7E-52 T 28-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 hmeg3_RS20505 f6c02a742f1b9f10939a0c62aa48553e 201 Gene3D G3DSA:3.40.30.10 3 201 7.1E-43 T 28-03-2018 hmeg3_RS15580 5e5623f89ea2637c5a20d5962b1b1657 478 Pfam PF00171 Aldehyde dehydrogenase family 19 473 3.3E-158 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15580 5e5623f89ea2637c5a20d5962b1b1657 478 Gene3D G3DSA:3.40.309.10 262 448 2.0E-64 T 28-03-2018 hmeg3_RS15580 5e5623f89ea2637c5a20d5962b1b1657 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15580 5e5623f89ea2637c5a20d5962b1b1657 478 Gene3D G3DSA:3.40.605.10 1 261 3.9E-82 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15580 5e5623f89ea2637c5a20d5962b1b1657 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 hmeg3_RS15580 5e5623f89ea2637c5a20d5962b1b1657 478 SUPERFAMILY SSF53720 3 475 5.11E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 hmeg3_RS01020 8e44470f1f2317faa1b32678f837f2ee 315 Pfam PF00892 EamA-like transporter family 165 301 5.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS01020 8e44470f1f2317faa1b32678f837f2ee 315 Pfam PF00892 EamA-like transporter family 9 142 3.8E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS01020 8e44470f1f2317faa1b32678f837f2ee 315 SUPERFAMILY SSF103481 44 146 7.32E-14 T 28-03-2018 hmeg3_RS01020 8e44470f1f2317faa1b32678f837f2ee 315 SUPERFAMILY SSF103481 212 305 2.88E-13 T 28-03-2018 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 Pfam PF13560 Helix-turn-helix domain 5 64 4.1E-8 T 28-03-2018 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 Gene3D G3DSA:3.40.1350.10 86 210 4.4E-5 T 28-03-2018 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 Gene3D G3DSA:1.25.10.10 375 1329 0.0014 T 28-03-2018 IPR011989 Armadillo-like helical hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 Gene3D G3DSA:3.30.1190.10 32 85 4.2E-8 T 28-03-2018 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 SMART SM00530 9 65 1.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 Gene3D G3DSA:3.40.50.300 251 370 3.9E-4 T 28-03-2018 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 Gene3D G3DSA:1.10.10.60 5 31 6.2E-10 T 28-03-2018 hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 SUPERFAMILY SSF52540 261 442 3.49E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS12980 8ebde75fbe356a4d873b57c4eb6b370e 1343 SUPERFAMILY SSF47413 4 69 1.61E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 hmeg3_RS04650 8d9a7d3d642676458e71a1725ef0797e 155 Gene3D G3DSA:3.10.129.10 12 138 1.7E-30 T 28-03-2018 hmeg3_RS04650 8d9a7d3d642676458e71a1725ef0797e 155 SUPERFAMILY SSF54637 16 135 1.13E-33 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS04650 8d9a7d3d642676458e71a1725ef0797e 155 Pfam PF03061 Thioesterase superfamily 29 104 4.2E-15 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 hmeg3_RS01470 ba5c6499f9888bbf86bb8c9eb9c15200 395 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 338 3.1E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS01470 ba5c6499f9888bbf86bb8c9eb9c15200 395 Gene3D G3DSA:1.10.3470.10 37 342 3.9E-26 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01470 ba5c6499f9888bbf86bb8c9eb9c15200 395 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 31 348 4.0E-133 T 28-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC hmeg3_RS01485 415c1a1dbb8d4be08650bfb8490bbff1 340 SUPERFAMILY SSF56317 13 275 5.1E-56 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS01485 415c1a1dbb8d4be08650bfb8490bbff1 340 Pfam PF00795 Carbon-nitrogen hydrolase 15 268 2.7E-46 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS01485 415c1a1dbb8d4be08650bfb8490bbff1 340 Gene3D G3DSA:3.60.110.10 1 339 1.5E-67 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS14915 718bda8c5c298577ef4d1775f0b4eb3b 172 Pfam PF04519 Polymer-forming cytoskeletal 60 155 8.8E-19 T 28-03-2018 IPR007607 Protein of unknown function DUF583 hmeg3_RS13075 cd41f2eee72777e1023a07b69e81ff92 109 Pfam PF08898 Domain of unknown function (DUF1843) 3 26 5.4E-7 T 28-03-2018 IPR014994 Domain of unknown function DUF1843 hmeg3_RS02955 e63562272302dabefca4304407d99667 311 PRINTS PR00412 Epoxide hydrolase signature 245 261 1.9E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS02955 e63562272302dabefca4304407d99667 311 PRINTS PR00412 Epoxide hydrolase signature 80 95 1.9E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS02955 e63562272302dabefca4304407d99667 311 PRINTS PR00412 Epoxide hydrolase signature 139 152 1.9E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS02955 e63562272302dabefca4304407d99667 311 PRINTS PR00412 Epoxide hydrolase signature 278 300 1.9E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 hmeg3_RS02955 e63562272302dabefca4304407d99667 311 Gene3D G3DSA:3.40.50.1820 46 307 2.8E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS02955 e63562272302dabefca4304407d99667 311 Pfam PF12697 Alpha/beta hydrolase family 70 295 5.4E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS02955 e63562272302dabefca4304407d99667 311 SUPERFAMILY SSF53474 25 302 8.86E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS21215 361533578c2edb283798aba524928aaa 408 Pfam PF13524 Glycosyl transferases group 1 229 315 1.9E-21 T 28-03-2018 hmeg3_RS21215 361533578c2edb283798aba524928aaa 408 Gene3D G3DSA:3.40.50.2000 74 306 1.0E-7 T 28-03-2018 hmeg3_RS10260 9be0e35c7c229557a1fa976756dec74d 446 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 6 361 5.2E-136 T 28-03-2018 IPR010839 Acyclic terpene utilisation hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 SUPERFAMILY SSF56176 347 425 2.18E-17 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 Pfam PF01595 Domain of unknown function DUF21 12 184 7.9E-44 T 28-03-2018 IPR002550 Domain of unknown function DUF21 hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 SMART SM01091 346 424 1.4E-18 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 Gene3D G3DSA:3.30.465.10 356 421 3.3E-12 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 Gene3D G3DSA:3.20.20.70 138 355 5.1E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 Pfam PF00571 CBS domain 282 328 1.5E-5 T 28-03-2018 IPR000644 CBS domain hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 Pfam PF03471 Transporter associated domain 348 421 3.8E-14 T 28-03-2018 IPR005170 Transporter-associated domain hmeg3_RS21900 09c49a8bd7b88fac92def301d46e0a44 433 SUPERFAMILY SSF54631 196 332 5.54E-26 T 28-03-2018 hmeg3_RS06770 8fcf099e9cca793e7d2e3661b068b01c 162 SUPERFAMILY SSF140804 43 157 3.79E-30 T 28-03-2018 IPR027405 YidB-like hmeg3_RS06770 8fcf099e9cca793e7d2e3661b068b01c 162 Gene3D G3DSA:1.10.10.690 1 158 1.4E-38 T 28-03-2018 hmeg3_RS06770 8fcf099e9cca793e7d2e3661b068b01c 162 Pfam PF06078 Bacterial protein of unknown function (DUF937) 9 134 3.7E-14 T 28-03-2018 IPR009282 Protein of unknown function DUF937 hmeg3_RS19510 be71987eee2db2e1f6c0e2d255481e62 412 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 42 324 2.4E-89 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 hmeg3_RS19510 be71987eee2db2e1f6c0e2d255481e62 412 SUPERFAMILY SSF55931 34 401 1.63E-95 T 28-03-2018 hmeg3_RS19510 be71987eee2db2e1f6c0e2d255481e62 412 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 44 318 3.7E-51 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 hmeg3_RS19510 be71987eee2db2e1f6c0e2d255481e62 412 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 412 76.085 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 426 2.8E-206 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 3.4E-113 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS13095 aa1fbc41a1ab5f370d6add85974557a4 427 Pfam PF02040 Arsenical pump membrane protein 4 423 4.1E-153 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 hmeg3_RS20575 477fb8f939c654d08a12f1358d7b1829 326 Gene3D G3DSA:3.40.50.1820 1 325 7.3E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20575 477fb8f939c654d08a12f1358d7b1829 326 Pfam PF12697 Alpha/beta hydrolase family 53 268 3.1E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS20575 477fb8f939c654d08a12f1358d7b1829 326 SUPERFAMILY SSF53474 34 321 6.36E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 Pfam PF01494 FAD binding domain 3 326 3.1E-15 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 Gene3D G3DSA:3.50.50.60 1 376 1.4E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.6E-13 T 28-03-2018 hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 4.6E-13 T 28-03-2018 hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 4.6E-13 T 28-03-2018 hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 SUPERFAMILY SSF51905 272 365 6.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS06365 d1193c42284007f481b9eaf3cd500aab 376 SUPERFAMILY SSF51905 3 168 6.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 hmeg3_RS18330 89630c422c5e5bfa336ae4c59328e382 398 Pfam PF01610 Transposase 275 397 3.6E-11 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain hmeg3_RS18330 89630c422c5e5bfa336ae4c59328e382 398 Pfam PF00487 Fatty acid desaturase 19 221 4.2E-12 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 hmeg3_RS19150 8b1fb3b417f5ae50e02bd7dfaf99da66 322 SUPERFAMILY SSF53590 1 316 6.8E-84 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain hmeg3_RS19150 8b1fb3b417f5ae50e02bd7dfaf99da66 322 Gene3D G3DSA:3.90.245.10 1 320 3.0E-93 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain hmeg3_RS19150 8b1fb3b417f5ae50e02bd7dfaf99da66 322 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 310 8.9E-78 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain hmeg3_RS23295 fc46229ec271cffbe099cba7c8f030ae 267 Pfam PF00149 Calcineurin-like phosphoesterase 1 221 1.8E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS23295 fc46229ec271cffbe099cba7c8f030ae 267 Gene3D G3DSA:3.60.21.10 1 259 1.7E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS23295 fc46229ec271cffbe099cba7c8f030ae 267 SUPERFAMILY SSF56300 149 255 5.84E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS23295 fc46229ec271cffbe099cba7c8f030ae 267 SUPERFAMILY SSF56300 1 110 5.84E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS17635 088527a50b088dd1b56e173a6f9a4c2e 213 Pfam PF09335 SNARE associated Golgi protein 49 174 9.7E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein hmeg3_RS10200 749b2f6d491cca1b60abfea62733fd2b 136 Pfam PF13924 Lipocalin-like domain 2 135 6.5E-33 T 28-03-2018 IPR024311 Lipocalin-like domain hmeg3_RS04385 ede18ad05b5c657077ae2ba724d227f6 142 Pfam PF06155 Protein of unknown function (DUF971) 11 94 5.7E-28 T 28-03-2018 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 Pfam PF04397 LytTr DNA-binding domain 175 270 7.1E-25 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 Pfam PF00072 Response regulator receiver domain 9 122 2.9E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 Gene3D G3DSA:2.40.50.40 165 233 3.6E-16 T 28-03-2018 hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 SMART SM00448 6 122 2.4E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 SUPERFAMILY SSF52172 7 134 2.56E-27 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 Gene3D G3DSA:3.40.50.2300 5 156 6.4E-25 T 28-03-2018 hmeg3_RS05515 86d843ed241f8e7096f3a4f89b078de8 270 SMART SM00850 174 270 1.0E-23 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 hmeg3_RS10295 88df9597aea198931bd44b89fca5f34f 141 Gene3D G3DSA:3.40.630.30 1 141 2.1E-34 T 28-03-2018 hmeg3_RS10295 88df9597aea198931bd44b89fca5f34f 141 SUPERFAMILY SSF55729 5 140 1.58E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS10295 88df9597aea198931bd44b89fca5f34f 141 Pfam PF13673 Acetyltransferase (GNAT) domain 23 139 9.8E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS13715 d29932e2b3cb05d34a334ecfc44629f2 104 PIRSF PIRSF019883 1 104 2.0E-33 T 28-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane hmeg3_RS13715 d29932e2b3cb05d34a334ecfc44629f2 104 Pfam PF10993 Protein of unknown function (DUF2818) 7 101 6.7E-35 T 28-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane hmeg3_RS10500 ab44fa666956671487c9df6fe0c273b2 765 Pfam PF13953 PapC C-terminal domain 690 745 2.8E-8 T 28-03-2018 IPR025949 PapC-like, C-terminal domain hmeg3_RS10500 ab44fa666956671487c9df6fe0c273b2 765 Pfam PF00577 Outer membrane usher protein 206 388 2.9E-10 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS10500 ab44fa666956671487c9df6fe0c273b2 765 Pfam PF00577 Outer membrane usher protein 469 672 6.8E-15 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 hmeg3_RS15050 06d30fc91bc79a705edebb985639abab 106 SMART SM00886 3 103 1.8E-23 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel hmeg3_RS15050 06d30fc91bc79a705edebb985639abab 106 Gene3D G3DSA:3.30.70.100 1 105 7.5E-21 T 28-03-2018 hmeg3_RS15050 06d30fc91bc79a705edebb985639abab 106 SUPERFAMILY SSF54909 2 102 3.62E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS15050 06d30fc91bc79a705edebb985639abab 106 Pfam PF07876 Stress responsive A/B Barrel Domain 3 102 4.5E-18 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel hmeg3_RS21810 4d6baa717da0de3a6c67acda1d46e531 89 Gene3D G3DSA:2.30.170.10 51 87 1.1E-4 T 28-03-2018 hmeg3_RS12445 4c0d98641f99f5e5cb6562a9435e8922 103 Gene3D G3DSA:3.40.30.10 1 96 1.9E-15 T 28-03-2018 hmeg3_RS12445 4c0d98641f99f5e5cb6562a9435e8922 103 SUPERFAMILY SSF52833 2 91 1.12E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS24560 575288dbd39a45ee561c5ce6724064b9 454 Gene3D G3DSA:3.30.1380.10 284 396 7.2E-6 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 hmeg3_RS24560 575288dbd39a45ee561c5ce6724064b9 454 Gene3D G3DSA:2.60.40.10 149 275 4.9E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold hmeg3_RS00910 2b1c8e5bea6f55a31cf94cfc87238d53 135 Gene3D G3DSA:1.10.10.10 1 135 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00910 2b1c8e5bea6f55a31cf94cfc87238d53 135 SUPERFAMILY SSF46785 7 110 1.94E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS00910 2b1c8e5bea6f55a31cf94cfc87238d53 135 Pfam PF01638 HxlR-like helix-turn-helix 19 103 5.9E-22 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS03770 c1fbf07ad2ded7a0fbb604e083be59b6 318 Gene3D G3DSA:1.10.3720.10 6 305 2.0E-34 T 28-03-2018 hmeg3_RS03770 c1fbf07ad2ded7a0fbb604e083be59b6 318 SUPERFAMILY SSF161098 95 297 4.45E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03770 c1fbf07ad2ded7a0fbb604e083be59b6 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 1.6E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24120 542aba03bb5894c0a8cb5e5a6697d35f 459 Gene3D G3DSA:3.40.50.1820 1 340 2.1E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS24120 542aba03bb5894c0a8cb5e5a6697d35f 459 SUPERFAMILY SSF53474 4 184 1.35E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 Gene3D G3DSA:3.40.50.1820 1 258 8.2E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 9 257 1.8E-83 T 28-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 Pfam PF12146 Serine aminopeptidase, S33 44 229 5.1E-15 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 SUPERFAMILY SSF53474 3 258 3.16E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 3.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 3.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 3.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS01285 708164b7cd8ce0f7e0252bae7260dbdd 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 3.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS20105 a64dc03757fe2bbbfa169306526d86cc 65 Pfam PF10276 Zinc-finger domain 31 54 3.3E-10 T 28-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 hmeg3_RS20105 a64dc03757fe2bbbfa169306526d86cc 65 Gene3D G3DSA:2.60.260.40 2 57 1.4E-18 T 28-03-2018 hmeg3_RS02825 f7ae66d2cdd9236205d9cd3febbcff01 299 Pfam PF01963 TraB family 31 297 4.6E-64 T 28-03-2018 IPR002816 Pheromone shutdown, TraB hmeg3_RS12595 9dd1597e1e08146f04e6e633c30dab90 234 PRINTS PR01837 MgtC/SapB protein signature 13 32 4.2E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 hmeg3_RS12595 9dd1597e1e08146f04e6e633c30dab90 234 PRINTS PR01837 MgtC/SapB protein signature 85 109 4.2E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 hmeg3_RS12595 9dd1597e1e08146f04e6e633c30dab90 234 PRINTS PR01837 MgtC/SapB protein signature 58 80 4.2E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 hmeg3_RS12595 9dd1597e1e08146f04e6e633c30dab90 234 PRINTS PR01837 MgtC/SapB protein signature 32 50 4.2E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 hmeg3_RS12595 9dd1597e1e08146f04e6e633c30dab90 234 Pfam PF02308 MgtC family 10 130 1.3E-34 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 hmeg3_RS07530 497a1ef832c591a0b971d18ea8ac8169 391 Gene3D G3DSA:3.40.710.10 82 386 5.8E-55 T 28-03-2018 hmeg3_RS07530 497a1ef832c591a0b971d18ea8ac8169 391 SUPERFAMILY SSF56601 30 375 1.74E-85 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like hmeg3_RS07530 497a1ef832c591a0b971d18ea8ac8169 391 Pfam PF00144 Beta-lactamase 94 375 1.1E-44 T 28-03-2018 IPR001466 Beta-lactamase-related hmeg3_RS04100 19fb59e67b09ffd9cfed95e31eeb814a 135 SUPERFAMILY SSF161084 5 128 2.09E-24 T 28-03-2018 hmeg3_RS04100 19fb59e67b09ffd9cfed95e31eeb814a 135 Gene3D G3DSA:1.20.120.550 1 135 1.5E-22 T 28-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain hmeg3_RS04100 19fb59e67b09ffd9cfed95e31eeb814a 135 Pfam PF01124 MAPEG family 8 131 6.9E-22 T 28-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein hmeg3_RS11560 d1a013fcfd2bdc5a4756bb6f653efae8 107 SUPERFAMILY SSF57716 70 103 4.13E-7 T 28-03-2018 hmeg3_RS11560 d1a013fcfd2bdc5a4756bb6f653efae8 107 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 70 102 3.0E-11 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 hmeg3_RS19590 e73b0de193d410dac4ad3676f2183eb2 462 PIRSF PIRSF006060 9 461 7.1E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 hmeg3_RS19590 e73b0de193d410dac4ad3676f2183eb2 462 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 hmeg3_RS19590 e73b0de193d410dac4ad3676f2183eb2 462 Pfam PF00324 Amino acid permease 27 459 3.7E-88 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 hmeg3_RS01170 be9d24806ecf331ff8f90d07a767183d 355 Gene3D G3DSA:1.10.3470.10 43 341 8.6E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01170 be9d24806ecf331ff8f90d07a767183d 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 326 7.2E-34 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS17470 01f13f0f48dcfe3206c60fe509f42129 178 Pfam PF00877 NlpC/P60 family 68 172 7.0E-27 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain hmeg3_RS17470 01f13f0f48dcfe3206c60fe509f42129 178 SUPERFAMILY SSF54001 53 177 9.32E-39 T 28-03-2018 hmeg3_RS17470 01f13f0f48dcfe3206c60fe509f42129 178 Gene3D G3DSA:3.90.1720.10 49 177 3.8E-37 T 28-03-2018 hmeg3_RS20650 bf1bc19c64bec5bae3b79e8645151879 145 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 32 122 6.8E-24 T 28-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 hmeg3_RS20650 bf1bc19c64bec5bae3b79e8645151879 145 Gene3D G3DSA:3.40.50.720 28 117 3.3E-4 T 28-03-2018 hmeg3_RS08075 2bcd7f87765e4a80a20982ebf0d4daa6 144 Pfam PF02082 Transcriptional regulator 3 84 1.1E-20 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type hmeg3_RS08075 2bcd7f87765e4a80a20982ebf0d4daa6 144 SUPERFAMILY SSF46785 5 135 6.12E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08075 2bcd7f87765e4a80a20982ebf0d4daa6 144 Gene3D G3DSA:1.10.10.10 1 144 1.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS13065 a4448b4fb29d253177324ea3f3317690 187 Gene3D G3DSA:1.20.5.40 106 135 1.4E-16 T 28-03-2018 hmeg3_RS13065 a4448b4fb29d253177324ea3f3317690 187 SUPERFAMILY SSF53041 1 136 1.05E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 hmeg3_RS13065 a4448b4fb29d253177324ea3f3317690 187 Gene3D G3DSA:3.40.50.1390 1 105 7.0E-30 T 28-03-2018 hmeg3_RS13065 a4448b4fb29d253177324ea3f3317690 187 Pfam PF00239 Resolvase, N terminal domain 3 136 6.0E-41 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 hmeg3_RS13065 a4448b4fb29d253177324ea3f3317690 187 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 hmeg3_RS13065 a4448b4fb29d253177324ea3f3317690 187 SMART SM00857 3 137 1.0E-49 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 hmeg3_RS16315 d8e9240b7127942d47dc19692e567e3d 122 SUPERFAMILY SSF54593 1 120 8.39E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS16315 d8e9240b7127942d47dc19692e567e3d 122 Gene3D G3DSA:3.10.180.10 7 119 1.3E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS03005 38a2380452ed90ff21cba1cab94ab168 259 SUPERFAMILY SSF161098 58 237 3.01E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03005 38a2380452ed90ff21cba1cab94ab168 259 Gene3D G3DSA:1.10.3720.10 53 252 2.9E-21 T 28-03-2018 hmeg3_RS03005 38a2380452ed90ff21cba1cab94ab168 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 239 1.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02685 3a5f475e8e77b8cbde7bb7f1d4acfba4 354 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 18 353 3.9E-108 T 28-03-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 hmeg3_RS02685 3a5f475e8e77b8cbde7bb7f1d4acfba4 354 Pfam PF03601 Conserved hypothetical protein 698 21 332 3.4E-102 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 hmeg3_RS01440 9bc5c5c454ddd17f6c7dd84cb1039781 299 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 34 274 1.9E-44 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 hmeg3_RS01440 9bc5c5c454ddd17f6c7dd84cb1039781 299 SUPERFAMILY SSF51197 30 281 2.16E-59 T 28-03-2018 hmeg3_RS01440 9bc5c5c454ddd17f6c7dd84cb1039781 299 Gene3D G3DSA:3.60.130.10 27 285 2.0E-51 T 28-03-2018 hmeg3_RS08880 c18e4adbbfec50c0f32ecd9b9beade07 216 Gene3D G3DSA:1.25.20.10 48 216 3.4E-6 T 28-03-2018 hmeg3_RS08880 c18e4adbbfec50c0f32ecd9b9beade07 216 SUPERFAMILY SSF48452 97 189 5.31E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS08880 c18e4adbbfec50c0f32ecd9b9beade07 216 PIRSF PIRSF006170 1 213 7.1E-62 T 28-03-2018 IPR026039 Uncharacterised protein family UPF0070 hmeg3_RS08880 c18e4adbbfec50c0f32ecd9b9beade07 216 Pfam PF09976 Tetratricopeptide repeat-like domain 15 208 2.8E-68 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 hmeg3_RS02055 8a7a37c2ff2224bd5c39b68a4504ed78 130 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 22 129 2.3E-13 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III hmeg3_RS22100 a067497d1493a6fabc030d619de40453 381 Pfam PF16113 Enoyl-CoA hydratase/isomerase 18 365 1.3E-112 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 hmeg3_RS22100 a067497d1493a6fabc030d619de40453 381 Gene3D G3DSA:3.90.226.10 1 359 6.6E-74 T 28-03-2018 hmeg3_RS22100 a067497d1493a6fabc030d619de40453 381 SUPERFAMILY SSF52096 9 207 4.32E-57 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS22100 a067497d1493a6fabc030d619de40453 381 SUPERFAMILY SSF52096 280 350 4.32E-57 T 28-03-2018 IPR029045 ClpP/crotonase-like domain hmeg3_RS11750 bc95427eb8d52c5877e5f58c89a29a33 693 Pfam PF13437 HlyD family secretion protein 535 614 1.3E-6 T 28-03-2018 hmeg3_RS16775 7309f3590e6df4fa92de8682121b8948 63 Pfam PF06945 Protein of unknown function (DUF1289) 11 55 8.0E-18 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 hmeg3_RS21620 d7e94e2b6246ed6615060f0067257ec6 278 SUPERFAMILY SSF56529 5 268 4.06E-36 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS21620 d7e94e2b6246ed6615060f0067257ec6 278 Gene3D G3DSA:3.90.850.10 1 277 3.3E-25 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 hmeg3_RS17300 025e011a42d10395991a276d35f09ea0 131 Pfam PF09842 Predicted membrane protein (DUF2069) 13 113 2.3E-35 T 28-03-2018 IPR018643 Protein of unknown function DUF2069, membrane hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 Pfam PF07549 SecD/SecF GG Motif 32 59 1.8E-7 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 285 5.8E-73 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 296 28.975 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 SUPERFAMILY SSF82866 72 296 1.7E-37 T 28-03-2018 hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 3.5E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 3.5E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 3.5E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 PRINTS PR01755 Bacterial translocase SecF protein signature 233 248 3.5E-27 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 Pfam PF02355 Protein export membrane protein 107 293 1.1E-61 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 97 282 8.9E-46 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial hmeg3_RS05075 372199613b56585a1a50713b7b9e307b 314 Gene3D G3DSA:1.20.1640.10 86 304 4.3E-31 T 28-03-2018 hmeg3_RS04585 62be11cc854a63e2940d4fc16a5ffb4e 325 SUPERFAMILY SSF161098 89 307 2.78E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04585 62be11cc854a63e2940d4fc16a5ffb4e 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 5.5E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04585 62be11cc854a63e2940d4fc16a5ffb4e 325 Gene3D G3DSA:1.10.3720.10 4 308 1.5E-38 T 28-03-2018 hmeg3_RS11975 71f412fa5955a7bbe9652cc1309d109c 267 Pfam PF01566 Natural resistance-associated macrophage protein 34 251 5.8E-53 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS15975 a4d9c81d14ee8f66f44a1b5ae9552124 174 Pfam PF07813 LTXXQ motif family protein 56 148 3.2E-21 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 hmeg3_RS04625 689e5c1726c24ff41c18252afe1b5eff 360 PIRSF PIRSF029285 1 355 4.4E-136 T 28-03-2018 IPR014553 Predicted aminopeptidase hmeg3_RS04625 689e5c1726c24ff41c18252afe1b5eff 360 Pfam PF10023 Putative aminopeptidase 29 348 6.8E-132 T 28-03-2018 IPR014553 Predicted aminopeptidase hmeg3_RS06815 893c89f9bd83479d7a2d6e9eccdb578b 1400 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 49 1387 3.2E-221 T 28-03-2018 IPR011836 Conserved hypothetical protein CHP02099 hmeg3_RS06815 893c89f9bd83479d7a2d6e9eccdb578b 1400 Pfam PF13116 Protein of unknown function 591 884 2.2E-58 T 28-03-2018 IPR025263 Domain of unknown function DUF3971 hmeg3_RS06815 893c89f9bd83479d7a2d6e9eccdb578b 1400 Pfam PF05170 AsmA family 71 207 1.9E-7 T 28-03-2018 IPR007844 AsmA hmeg3_RS06815 893c89f9bd83479d7a2d6e9eccdb578b 1400 Pfam PF13502 AsmA-like C-terminal region 1136 1379 7.6E-64 T 28-03-2018 IPR032712 AsmA-like, C-terminal hmeg3_RS24060 0b2fa018bec3b1a3e84ea159cf5015d3 839 Gene3D G3DSA:1.25.40.10 354 718 8.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 hmeg3_RS16240 ff9bad29d3b61c7dfc0f09377601ce63 189 Pfam PF11659 Protein of unknown function (DUF3261) 49 185 1.2E-39 T 28-03-2018 IPR021675 Protein of unknown function DUF3261 hmeg3_RS10020 8a3bc380c77a36eb4706acd01bb27ed4 284 Pfam PF03618 Kinase/pyrophosphorylase 20 276 8.2E-81 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 hmeg3_RS10020 8a3bc380c77a36eb4706acd01bb27ed4 284 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 17 284 75.71 T 28-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein hmeg3_RS10360 990367de0bc9707286cb30e2ddde655f 486 Gene3D G3DSA:2.130.10.10 49 366 0.0026 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 hmeg3_RS10360 990367de0bc9707286cb30e2ddde655f 486 Pfam PF03929 PepSY-associated TM region 7 295 8.9E-10 T 28-03-2018 IPR005625 PepSY-associated TM protein hmeg3_RS24010 9fbc422c7f6832bb5c40d88a2b7160c1 420 Gene3D G3DSA:1.10.10.10 158 399 7.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS11415 f73e89f7e27cec4d70edb901c068e5d6 140 Pfam PF04134 Protein of unknown function, DUF393 15 121 4.6E-21 T 28-03-2018 IPR007263 Protein of unknown function DUF393 hmeg3_RS19140 8b50dc159c5bc4b009bfd36430743a07 259 SUPERFAMILY SSF161098 6 251 4.45E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS19140 8b50dc159c5bc4b009bfd36430743a07 259 Gene3D G3DSA:1.10.3720.10 3 251 3.7E-35 T 28-03-2018 hmeg3_RS19140 8b50dc159c5bc4b009bfd36430743a07 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 248 8.0E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS12580 1fa874c2302945b8cb0053658b1d3fa7 131 Pfam PF03788 LrgA family 12 104 1.1E-27 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 hmeg3_RS21970 31f3fcebaa67005788f349268606e69a 169 Pfam PF05258 Protein of unknown function (DUF721) 47 110 1.0E-6 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 hmeg3_RS21660 c45d688d5ac95bc3b642700f34338e79 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 hmeg3_RS21660 c45d688d5ac95bc3b642700f34338e79 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 203 1.7E-60 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS21660 c45d688d5ac95bc3b642700f34338e79 217 PIRSF PIRSF000709 2 191 1.0E-16 T 28-03-2018 hmeg3_RS21660 c45d688d5ac95bc3b642700f34338e79 217 Gene3D G3DSA:3.40.50.1240 1 216 1.5E-56 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS21660 c45d688d5ac95bc3b642700f34338e79 217 SUPERFAMILY SSF53254 1 209 5.11E-58 T 28-03-2018 IPR029033 Histidine phosphatase superfamily hmeg3_RS21660 c45d688d5ac95bc3b642700f34338e79 217 SMART SM00855 3 164 2.4E-25 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 hmeg3_RS22075 99f896317dcba5e79df95d099a4cf8d7 343 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 59 299 7.9E-58 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS22075 99f896317dcba5e79df95d099a4cf8d7 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 59 324 8.6E-69 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS22075 99f896317dcba5e79df95d099a4cf8d7 343 PIRSF PIRSF006470 9 336 1.4E-68 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 hmeg3_RS22075 99f896317dcba5e79df95d099a4cf8d7 343 Gene3D G3DSA:3.40.190.10 164 294 0.0094 T 28-03-2018 hmeg3_RS01650 1d68da45ecccaab407a971ef3dd8a47c 329 Pfam PF03595 Voltage-dependent anion channel 21 318 4.7E-47 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 hmeg3_RS14625 30592afb9926a978dbbaa70f8d53ef6d 407 SUPERFAMILY SSF53822 52 398 2.62E-80 T 28-03-2018 IPR028082 Periplasmic binding protein-like I hmeg3_RS14625 30592afb9926a978dbbaa70f8d53ef6d 407 Gene3D G3DSA:3.40.50.2300 50 383 8.2E-56 T 28-03-2018 hmeg3_RS14625 30592afb9926a978dbbaa70f8d53ef6d 407 Pfam PF13458 Periplasmic binding protein 53 394 4.4E-56 T 28-03-2018 IPR028081 Leucine-binding protein domain hmeg3_RS23675 0735a672fc0da64ab9f4ea0075df5868 522 SUPERFAMILY SSF56925 383 521 3.53E-10 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS23675 0735a672fc0da64ab9f4ea0075df5868 522 Gene3D G3DSA:1.25.40.120 57 392 1.5E-5 T 28-03-2018 hmeg3_RS17070 72c1528185ce69e916acbdff5ef00e99 432 PIRSF PIRSF005353 1 431 5.5E-179 T 28-03-2018 IPR026033 Purine permease PbuG-like hmeg3_RS17070 72c1528185ce69e916acbdff5ef00e99 432 Pfam PF00860 Permease family 20 391 5.8E-56 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS14935 e80db449cf944f6a423cafc34864f3ab 116 Pfam PF12680 SnoaL-like domain 7 105 2.5E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain hmeg3_RS14935 e80db449cf944f6a423cafc34864f3ab 116 SUPERFAMILY SSF54427 3 112 3.56E-32 T 28-03-2018 IPR032710 NTF2-like domain hmeg3_RS14935 e80db449cf944f6a423cafc34864f3ab 116 Gene3D G3DSA:3.10.450.50 2 115 8.0E-16 T 28-03-2018 hmeg3_RS05490 6a7c3aaddc4484e890d2afa3c42e2f9f 169 Pfam PF09351 Domain of unknown function (DUF1993) 6 166 1.3E-60 T 28-03-2018 IPR018531 Domain of unknown function DUF1993 hmeg3_RS05490 6a7c3aaddc4484e890d2afa3c42e2f9f 169 SUPERFAMILY SSF109854 4 168 5.58E-60 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes hmeg3_RS05490 6a7c3aaddc4484e890d2afa3c42e2f9f 169 Gene3D G3DSA:1.20.120.450 2 169 2.5E-67 T 28-03-2018 hmeg3_RS03930 b73bd886c9e73e49c168cfff4ee69196 257 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 73 227 1.7E-21 T 28-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 Pfam PF13537 Glutamine amidotransferase domain 81 215 3.2E-13 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 Pfam PF00156 Phosphoribosyl transferase domain 282 395 9.6E-12 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 1.2E-154 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 Gene3D G3DSA:3.40.50.2020 296 428 1.0E-23 T 28-03-2018 hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.7 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 SUPERFAMILY SSF56235 2 259 5.32E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 SUPERFAMILY SSF53271 252 484 1.97E-70 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 Gene3D G3DSA:3.60.20.10 2 295 1.1E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS17185 bbceab35226bc99a644c572019e26daf 506 PIRSF PIRSF000485 1 482 2.0E-155 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 hmeg3_RS10170 dcd374b677ac410b05836657d5b39e21 92 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 69 3.4E-9 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain hmeg3_RS10170 dcd374b677ac410b05836657d5b39e21 92 SUPERFAMILY SSF54909 1 66 1.39E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS10170 dcd374b677ac410b05836657d5b39e21 92 Gene3D G3DSA:3.30.70.100 1 87 2.5E-13 T 28-03-2018 hmeg3_RS07470 2f77c43d3163f83e94979fdcb93b2c56 412 Gene3D G3DSA:3.40.50.450 4 163 3.5E-14 T 28-03-2018 hmeg3_RS10665 5297d5d3821f9552b36722dde71b4d1e 501 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 20 470 1.5E-139 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 hmeg3_RS10665 5297d5d3821f9552b36722dde71b4d1e 501 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 17 487 43.812 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 hmeg3_RS14630 19c10f7f33901631b0d3d47142cd5389 140 Pfam PF08897 Domain of unknown function (DUF1841) 5 139 2.1E-60 T 28-03-2018 IPR014993 Protein of unknown function DUF1841 hmeg3_RS12530 8311d9870b5bbc59e161b82ef0c28f90 285 Gene3D G3DSA:2.40.33.20 1 284 1.4E-46 T 28-03-2018 hmeg3_RS12530 8311d9870b5bbc59e161b82ef0c28f90 285 SUPERFAMILY SSF50800 2 50 7.74E-13 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain hmeg3_RS12530 8311d9870b5bbc59e161b82ef0c28f90 285 SUPERFAMILY SSF50800 152 234 7.74E-13 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain hmeg3_RS12530 8311d9870b5bbc59e161b82ef0c28f90 285 SUPERFAMILY SSF141673 4 133 4.45E-38 T 28-03-2018 hmeg3_RS12530 8311d9870b5bbc59e161b82ef0c28f90 285 Pfam PF03473 MOSC domain 144 278 7.1E-27 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 hmeg3_RS12530 8311d9870b5bbc59e161b82ef0c28f90 285 Pfam PF03476 MOSC N-terminal beta barrel domain 1 117 5.7E-29 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel hmeg3_RS06720 b964de297592a88018df81a6ee37ba7d 228 SUPERFAMILY SSF52499 8 206 1.57E-57 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS06720 b964de297592a88018df81a6ee37ba7d 228 Pfam PF00857 Isochorismatase family 18 206 8.0E-46 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS06720 b964de297592a88018df81a6ee37ba7d 228 Gene3D G3DSA:3.40.50.850 9 225 1.1E-57 T 28-03-2018 hmeg3_RS22415 dfdaa9a630cbac8e713656c7675798ba 214 Pfam PF04367 Protein of unknown function (DUF502) 56 161 2.0E-38 T 28-03-2018 IPR007462 Protein of unknown function DUF502 hmeg3_RS02530 359f1549c8181ba16a5a062fdb4e382b 203 Pfam PF00857 Isochorismatase family 23 195 2.5E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS02530 359f1549c8181ba16a5a062fdb4e382b 203 SUPERFAMILY SSF52499 3 199 8.9E-49 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 hmeg3_RS02530 359f1549c8181ba16a5a062fdb4e382b 203 Gene3D G3DSA:3.40.50.850 7 202 1.6E-45 T 28-03-2018 hmeg3_RS17415 e5dac78afe5112c409532a5a8116926d 557 Pfam PF00999 Sodium/hydrogen exchanger family 9 422 1.8E-66 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 hmeg3_RS17415 e5dac78afe5112c409532a5a8116926d 557 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 550 6.9E-137 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 hmeg3_RS08430 1bab603071316efbd8d902e9eefd5edf 351 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 256 3.0E-46 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 hmeg3_RS08430 1bab603071316efbd8d902e9eefd5edf 351 SUPERFAMILY SSF51735 2 341 1.64E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS08430 1bab603071316efbd8d902e9eefd5edf 351 Gene3D G3DSA:3.40.50.720 1 350 2.2E-45 T 28-03-2018 hmeg3_RS12210 9a36d8643683386b2ceb4297d13e2c31 286 Pfam PF08668 HDOD domain 13 200 4.9E-47 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS12210 9a36d8643683386b2ceb4297d13e2c31 286 Gene3D G3DSA:1.10.3210.10 1 277 3.4E-34 T 28-03-2018 hmeg3_RS12210 9a36d8643683386b2ceb4297d13e2c31 286 SUPERFAMILY SSF109604 4 268 2.89E-60 T 28-03-2018 hmeg3_RS17620 887b3f729844b7be01699c0d5a4069cf 300 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 70 223 3.5E-48 T 28-03-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 hmeg3_RS17620 887b3f729844b7be01699c0d5a4069cf 300 SUPERFAMILY SSF51197 102 223 7.14E-19 T 28-03-2018 hmeg3_RS17620 887b3f729844b7be01699c0d5a4069cf 300 Gene3D G3DSA:2.60.120.330 61 246 4.9E-45 T 28-03-2018 IPR027443 Isopenicillin N synthase-like hmeg3_RS22990 fa55ef6bf16f99170aa67b4dae5274cd 135 Pfam PF03610 PTS system fructose IIA component 3 106 3.3E-17 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 hmeg3_RS22990 fa55ef6bf16f99170aa67b4dae5274cd 135 SUPERFAMILY SSF53062 1 127 1.7E-28 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 hmeg3_RS22990 fa55ef6bf16f99170aa67b4dae5274cd 135 Gene3D G3DSA:3.40.50.510 1 135 4.5E-31 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 hmeg3_RS21825 4130be0898fd93b0e26abfb49a1413d3 273 Gene3D G3DSA:1.10.3720.10 8 270 2.7E-26 T 28-03-2018 hmeg3_RS21825 4130be0898fd93b0e26abfb49a1413d3 273 SUPERFAMILY SSF161098 72 255 1.03E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21825 4130be0898fd93b0e26abfb49a1413d3 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 263 3.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS02470 9bd4bdc9ca5f891a8b54e3e260323772 256 Gene3D G3DSA:3.40.50.1110 56 252 9.6E-25 T 28-03-2018 hmeg3_RS02470 9bd4bdc9ca5f891a8b54e3e260323772 256 SUPERFAMILY SSF52266 52 243 2.54E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain hmeg3_RS02470 9bd4bdc9ca5f891a8b54e3e260323772 256 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 59 231 2.3E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain hmeg3_RS02410 baf2ecbcf5fd5fce3263d19631a7c0b2 114 Pfam PF03899 ATP synthase I chain 3 98 9.3E-18 T 28-03-2018 IPR005598 ATP synthase protein I hmeg3_RS14420 557ab35004197feb309a259c125fe602 261 SUPERFAMILY SSF161098 10 256 2.75E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS14420 557ab35004197feb309a259c125fe602 261 Gene3D G3DSA:1.10.3720.10 1 255 5.5E-37 T 28-03-2018 hmeg3_RS14420 557ab35004197feb309a259c125fe602 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 255 2.8E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS23030 2e38e8b743452c8bc60e350ff388bed6 678 Pfam PF03169 OPT oligopeptide transporter protein 14 632 4.1E-102 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 hmeg3_RS23030 2e38e8b743452c8bc60e350ff388bed6 678 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 10 632 5.9E-107 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 hmeg3_RS23030 2e38e8b743452c8bc60e350ff388bed6 678 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 14 634 5.9E-209 T 28-03-2018 IPR004814 Oligopeptide transporter OPT hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 SMART SM01001 1 146 3.4E-90 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 146 3.4E-60 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 Gene3D G3DSA:3.40.50.7700 1 153 2.0E-61 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 PIRSF PIRSF001338 1 151 1.2E-60 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 SUPERFAMILY SSF52255 1 150 3.66E-62 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 150 27.976 T 28-03-2018 IPR033747 Class I PurE hmeg3_RS20060 3577bb08cd836722f3d8728c3305c8a4 153 Pfam PF00731 AIR carboxylase 1 143 7.0E-60 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 hmeg3_RS19865 322b19dafe0548ec58b716b8ee46c238 249 Gene3D G3DSA:3.40.1130.10 34 248 1.4E-42 T 28-03-2018 hmeg3_RS19865 322b19dafe0548ec58b716b8ee46c238 249 SMART SM00563 74 189 2.5E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS19865 322b19dafe0548ec58b716b8ee46c238 249 SUPERFAMILY SSF69593 6 242 2.35E-42 T 28-03-2018 hmeg3_RS19865 322b19dafe0548ec58b716b8ee46c238 249 Pfam PF01553 Acyltransferase 62 186 1.8E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 hmeg3_RS23095 dbc4b641a408b7f792eb9be3ddf38a94 633 Pfam PF02705 K+ potassium transporter 22 554 1.8E-210 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 hmeg3_RS23095 dbc4b641a408b7f792eb9be3ddf38a94 633 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 13 633 34.201 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup hmeg3_RS19400 067e8843700e03a9f3d5a2c067de51bb 192 Pfam PF13958 Toxin ToxN, type III toxin-antitoxin system 28 185 7.2E-46 T 28-03-2018 IPR025911 ToxN/AbiQ toxin GO:0003723|GO:0004521 hmeg3_RS23595 df24cdffaab76b312d9c4939c6288c71 709 Pfam PF03235 Protein of unknown function DUF262 18 329 6.6E-25 T 28-03-2018 IPR004919 Domain of unknown function DUF262 hmeg3_RS23595 df24cdffaab76b312d9c4939c6288c71 709 Pfam PF07510 Protein of unknown function (DUF1524) 586 680 9.0E-5 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 hmeg3_RS07680 7d1e62d59a973b4450119ee82f103c34 662 Pfam PF01757 Acyltransferase family 11 337 4.8E-26 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 hmeg3_RS17955 786dab2116d0a1cc2da7d131090f2851 110 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 85 5.3E-18 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 hmeg3_RS09335 72815f364056fc6eb909d31c36141ef2 281 SUPERFAMILY SSF103481 42 134 2.48E-11 T 28-03-2018 hmeg3_RS09335 72815f364056fc6eb909d31c36141ef2 281 Pfam PF00892 EamA-like transporter family 146 278 4.8E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS09335 72815f364056fc6eb909d31c36141ef2 281 SUPERFAMILY SSF103481 185 279 4.58E-14 T 28-03-2018 hmeg3_RS18610 f590b36ed069d032197c25b11d0a757e 131 Gene3D G3DSA:3.40.50.2300 1 131 1.8E-26 T 28-03-2018 hmeg3_RS18610 f590b36ed069d032197c25b11d0a757e 131 Pfam PF00072 Response regulator receiver domain 8 110 8.3E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18610 f590b36ed069d032197c25b11d0a757e 131 SMART SM00448 6 119 2.7E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 hmeg3_RS18610 f590b36ed069d032197c25b11d0a757e 131 SUPERFAMILY SSF52172 5 124 4.27E-26 T 28-03-2018 IPR011006 CheY-like superfamily hmeg3_RS13100 7639d1650a09192d61fe7182e2f178a3 143 SUPERFAMILY SSF52833 3 137 8.95E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS13100 7639d1650a09192d61fe7182e2f178a3 143 Pfam PF03960 ArsC family 6 113 1.9E-16 T 28-03-2018 IPR006660 Arsenate reductase-like hmeg3_RS13100 7639d1650a09192d61fe7182e2f178a3 143 Gene3D G3DSA:3.40.30.10 1 140 1.1E-39 T 28-03-2018 hmeg3_RS13100 7639d1650a09192d61fe7182e2f178a3 143 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 115 2.0E-41 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 hmeg3_RS02885 d98d1e2ea43aba588766bdb4abedd0af 116 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 104 4.0E-33 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV hmeg3_RS21500 a0fe6693da64dfca1c6ed67e0df4b370 322 Gene3D G3DSA:1.10.3720.10 37 320 3.1E-44 T 28-03-2018 hmeg3_RS21500 a0fe6693da64dfca1c6ed67e0df4b370 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 317 2.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS21500 a0fe6693da64dfca1c6ed67e0df4b370 322 SUPERFAMILY SSF161098 81 306 4.97E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS24465 08df78c2b0bfd7f580eb38502a876962 549 Pfam PF03929 PepSY-associated TM region 10 374 1.1E-66 T 28-03-2018 IPR005625 PepSY-associated TM protein hmeg3_RS12145 efd23517defe5f0a2170f1a834f12bac 264 Gene3D G3DSA:3.40.190.10 120 217 1.0E-15 T 28-03-2018 hmeg3_RS12145 efd23517defe5f0a2170f1a834f12bac 264 SUPERFAMILY SSF53850 10 255 1.9E-53 T 28-03-2018 hmeg3_RS12145 efd23517defe5f0a2170f1a834f12bac 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 254 5.3E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS12145 efd23517defe5f0a2170f1a834f12bac 264 Gene3D G3DSA:3.40.190.10 32 119 1.5E-24 T 28-03-2018 hmeg3_RS12145 efd23517defe5f0a2170f1a834f12bac 264 SMART SM00062 37 256 1.4E-40 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF hmeg3_RS18205 20f2228adb0945c9b30f99f77c827502 71 Pfam PF05433 Glycine zipper 2TM domain 33 70 1.7E-6 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 hmeg3_RS04180 dc8b3aab4e70d7d50037ff02aa520f1d 279 Pfam PF07103 Protein of unknown function (DUF1365) 13 261 5.3E-69 T 28-03-2018 IPR010775 Protein of unknown function DUF1365 hmeg3_RS04795 c472a0c48a45660b5d2f6cd1620b458d 304 Pfam PF00892 EamA-like transporter family 4 135 2.8E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS04795 c472a0c48a45660b5d2f6cd1620b458d 304 SUPERFAMILY SSF103481 199 285 2.62E-8 T 28-03-2018 hmeg3_RS04795 c472a0c48a45660b5d2f6cd1620b458d 304 SUPERFAMILY SSF103481 40 139 5.23E-5 T 28-03-2018 hmeg3_RS01405 c97b1530d3910845d993345514862b31 94 Pfam PF13663 Domain of unknown function (DUF4148) 1 47 1.9E-8 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS00550 fe3ef5322697d96e1ee6df04ee1c1f27 323 SUPERFAMILY SSF51412 11 310 1.1E-60 T 28-03-2018 hmeg3_RS00550 fe3ef5322697d96e1ee6df04ee1c1f27 323 Pfam PF03060 Nitronate monooxygenase 15 311 1.9E-22 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 hmeg3_RS00550 fe3ef5322697d96e1ee6df04ee1c1f27 323 Gene3D G3DSA:3.20.20.70 8 323 8.9E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 hmeg3_RS05200 953713b441958ecd3ae03a4ce710f9d9 295 SUPERFAMILY SSF55486 164 229 7.33E-5 T 28-03-2018 hmeg3_RS05200 953713b441958ecd3ae03a4ce710f9d9 295 Pfam PF04228 Putative neutral zinc metallopeptidase 1 290 4.3E-123 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative hmeg3_RS14315 4130832857a9891e14c5cfa6c11b1b80 240 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 240 97.98 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 hmeg3_RS14315 4130832857a9891e14c5cfa6c11b1b80 240 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 32 224 6.0E-57 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 hmeg3_RS14315 4130832857a9891e14c5cfa6c11b1b80 240 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 33 211 1.5E-72 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 hmeg3_RS14315 4130832857a9891e14c5cfa6c11b1b80 240 SUPERFAMILY SSF55729 2 233 1.59E-89 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS09340 ff2bbb1ad1e52afc1e2f801a739eeb85 182 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 3 180 7.1E-73 T 28-03-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein hmeg3_RS09340 ff2bbb1ad1e52afc1e2f801a739eeb85 182 SUPERFAMILY SSF109604 14 64 1.41E-7 T 28-03-2018 hmeg3_RS11820 108b5ba34db0ab06cd3a8f137dffc586 176 Pfam PF01566 Natural resistance-associated macrophage protein 1 151 2.8E-30 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 hmeg3_RS17250 9dac69536771f916b13e49af1e840110 80 Pfam PF04226 Transglycosylase associated protein 33 80 1.8E-13 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 hmeg3_RS18455 b6310369725ee6112255352893cdddee 55 TIGRFAM TIGR03510 XapX: XapX domain 7 50 7.8E-11 T 28-03-2018 IPR020017 XapX domain hmeg3_RS05365 909549a5c64c250eb35675049cb27732 137 Gene3D G3DSA:3.90.1200.10 3 127 0.001 T 28-03-2018 hmeg3_RS20100 778a09261507bf3ecd834df45a19e96f 306 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 1.0E-136 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 hmeg3_RS20100 778a09261507bf3ecd834df45a19e96f 306 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 222 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS20100 778a09261507bf3ecd834df45a19e96f 306 Gene3D G3DSA:3.30.470.10 1 142 3.2E-42 T 28-03-2018 hmeg3_RS20100 778a09261507bf3ecd834df45a19e96f 306 SUPERFAMILY SSF56752 1 303 5.23E-107 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS20100 778a09261507bf3ecd834df45a19e96f 306 Gene3D G3DSA:3.20.10.10 143 295 1.2E-51 T 28-03-2018 hmeg3_RS20100 778a09261507bf3ecd834df45a19e96f 306 Pfam PF01063 Amino-transferase class IV 36 266 1.6E-60 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 hmeg3_RS10715 0d482201bc87e6683e682ec06324aa12 340 SUPERFAMILY SSF53850 24 331 4.54E-70 T 28-03-2018 hmeg3_RS10715 0d482201bc87e6683e682ec06324aa12 340 PIRSF PIRSF002825 6 334 2.0E-91 T 28-03-2018 IPR026045 Ferric binding protein hmeg3_RS10715 0d482201bc87e6683e682ec06324aa12 340 Pfam PF13343 Bacterial extracellular solute-binding protein 75 302 3.0E-29 T 28-03-2018 hmeg3_RS10715 0d482201bc87e6683e682ec06324aa12 340 Gene3D G3DSA:3.40.190.10 145 283 7.5E-31 T 28-03-2018 hmeg3_RS10715 0d482201bc87e6683e682ec06324aa12 340 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 18 338 4.2E-164 T 28-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative hmeg3_RS10715 0d482201bc87e6683e682ec06324aa12 340 Gene3D G3DSA:3.40.190.10 20 144 4.1E-15 T 28-03-2018 hmeg3_RS21725 ce7a512735831d15394a969fe5ffb149 189 Gene3D G3DSA:3.40.1410.10 2 183 1.9E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain hmeg3_RS21725 ce7a512735831d15394a969fe5ffb149 189 Pfam PF04345 Chorismate lyase 5 180 8.5E-27 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 hmeg3_RS21725 ce7a512735831d15394a969fe5ffb149 189 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 8 184 23.938 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 hmeg3_RS21725 ce7a512735831d15394a969fe5ffb149 189 SUPERFAMILY SSF64288 11 181 1.73E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain hmeg3_RS05130 81d9fa01e0ccfb0badb1307320fa1f30 643 Pfam PF01594 AI-2E family transporter 175 366 5.6E-32 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like hmeg3_RS05130 81d9fa01e0ccfb0badb1307320fa1f30 643 Pfam PF01594 AI-2E family transporter 21 130 2.7E-8 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like hmeg3_RS12560 4c87082d5d4b8cdacfd94d25bae5f83c 254 Gene3D G3DSA:3.40.630.30 21 222 3.3E-28 T 28-03-2018 hmeg3_RS12560 4c87082d5d4b8cdacfd94d25bae5f83c 254 Pfam PF13302 Acetyltransferase (GNAT) domain 43 181 2.7E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 hmeg3_RS12560 4c87082d5d4b8cdacfd94d25bae5f83c 254 SUPERFAMILY SSF55729 31 205 3.47E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 Pfam PF01019 Gamma-glutamyltranspeptidase 38 539 1.4E-150 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 SUPERFAMILY SSF56235 7 544 9.07E-174 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 114 132 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 271 290 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 441 458 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 45 70 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 242 258 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 132 151 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 417 432 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 362 380 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS24445 f2d6a2095e3bbf11f27da3ce9e2ec37e 544 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 386 404 2.9E-41 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 hmeg3_RS03865 dca9fd57aae5ab6efda3c27ae2548e35 305 SUPERFAMILY SSF161098 91 286 6.02E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03865 dca9fd57aae5ab6efda3c27ae2548e35 305 Gene3D G3DSA:1.10.3720.10 4 292 2.0E-47 T 28-03-2018 hmeg3_RS03865 dca9fd57aae5ab6efda3c27ae2548e35 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 1.7E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04570 1585507dcea1c5f12a093fffe1f4ea0e 117 Pfam PF06993 Protein of unknown function (DUF1304) 11 114 5.7E-40 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 hmeg3_RS23955 ce774b0a9bd7b67c15c01dc75120a4e3 314 Pfam PF02690 Na+/Pi-cotransporter 16 149 2.7E-37 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 hmeg3_RS23955 ce774b0a9bd7b67c15c01dc75120a4e3 314 Pfam PF02690 Na+/Pi-cotransporter 168 263 6.5E-14 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 hmeg3_RS21030 8af63d775af1c1d1258a6bbe1b9a8175 117 Pfam PF11287 Protein of unknown function (DUF3088) 3 113 3.9E-39 T 28-03-2018 IPR021439 Protein of unknown function DUF3088 hmeg3_RS15105 1c85cccceb5fa0615aca537f8336d5c9 203 Pfam PF16157 Domain of unknown function (DUF4865) 18 194 1.3E-39 T 28-03-2018 IPR032349 Protein of unknown function DUF4865 hmeg3_RS23065 a92d9278e201736ada97ff42d4b5397e 179 Pfam PF14334 Domain of unknown function (DUF4390) 17 174 4.0E-57 T 28-03-2018 IPR025500 Protein of unknown function DUF4390 hmeg3_RS21145 6fb466c23a60452926f1e70162a21bf4 289 Pfam PF11004 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase 18 288 1.4E-117 T 28-03-2018 IPR021266 Kdo hydroxylase hmeg3_RS18405 1b9a1621fcf4d443828223d3eab82f7c 201 Pfam PF01618 MotA/TolQ/ExbB proton channel family 66 186 8.8E-35 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 hmeg3_RS20090 c6292c2de1047b25e86e7ad338e3e0ff 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 104 4.3E-23 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD hmeg3_RS05335 37fe2f86ab075972afbe6e1b17a5342b 55 TIGRFAM TIGR03510 XapX: XapX domain 4 50 2.1E-18 T 28-03-2018 IPR020017 XapX domain hmeg3_RS05335 37fe2f86ab075972afbe6e1b17a5342b 55 Pfam PF07235 Protein of unknown function (DUF1427) 3 54 4.3E-22 T 28-03-2018 IPR009872 Protein of unknown function DUF1427 hmeg3_RS23185 db07a09cb3eb1b19fc64d080a4a263e3 79 Pfam PF12512 Protein of unknown function (DUF3717) 6 71 1.5E-25 T 28-03-2018 IPR022191 Protein of unknown function DUF3717 hmeg3_RS03960 d03ed01bfacd18df611ba4ae57570266 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 8.0E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03960 d03ed01bfacd18df611ba4ae57570266 314 SUPERFAMILY SSF161098 91 295 2.18E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS03960 d03ed01bfacd18df611ba4ae57570266 314 Gene3D G3DSA:1.10.3720.10 3 301 2.3E-39 T 28-03-2018 hmeg3_RS12310 1cc98b22f700f647da3a37cf54f16c53 259 Gene3D G3DSA:3.40.50.1820 1 257 3.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS12310 1cc98b22f700f647da3a37cf54f16c53 259 Pfam PF12697 Alpha/beta hydrolase family 30 249 1.6E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS12310 1cc98b22f700f647da3a37cf54f16c53 259 SUPERFAMILY SSF53474 9 255 1.05E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00745 01a426cf3665599d472f557ac69056ae 110 SUPERFAMILY SSF103481 7 106 2.35E-21 T 28-03-2018 hmeg3_RS00745 01a426cf3665599d472f557ac69056ae 110 Pfam PF00893 Small Multidrug Resistance protein 4 94 2.7E-29 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 hmeg3_RS14105 8d425ddeeeb53b93bea03e5ab599183b 135 Pfam PF05154 TM2 domain 7 53 3.8E-16 T 28-03-2018 IPR007829 TM2 domain hmeg3_RS14105 8d425ddeeeb53b93bea03e5ab599183b 135 Pfam PF05154 TM2 domain 72 118 2.9E-14 T 28-03-2018 IPR007829 TM2 domain hmeg3_RS07135 ee2173b29f7938b64d420b20b10f17d9 216 Gene3D G3DSA:1.10.287.70 65 216 2.2E-6 T 28-03-2018 hmeg3_RS07135 ee2173b29f7938b64d420b20b10f17d9 216 Pfam PF07077 Protein of unknown function (DUF1345) 35 206 9.7E-59 T 28-03-2018 IPR009781 Protein of unknown function DUF1345 hmeg3_RS15645 d4242167b9c2ce5d5a30ee26857a6fec 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 1.1E-31 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS15645 d4242167b9c2ce5d5a30ee26857a6fec 218 Gene3D G3DSA:1.10.3720.10 3 218 1.8E-43 T 28-03-2018 hmeg3_RS15645 d4242167b9c2ce5d5a30ee26857a6fec 218 SUPERFAMILY SSF161098 11 201 1.31E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS15645 d4242167b9c2ce5d5a30ee26857a6fec 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 211 5.3E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS18640 2f5dbda5864dc5b1d10c3771d4fb831f 310 Pfam PF08668 HDOD domain 19 214 7.1E-39 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD hmeg3_RS18640 2f5dbda5864dc5b1d10c3771d4fb831f 310 Gene3D G3DSA:1.10.3210.10 2 278 4.7E-31 T 28-03-2018 hmeg3_RS18640 2f5dbda5864dc5b1d10c3771d4fb831f 310 SUPERFAMILY SSF109604 12 251 8.48E-43 T 28-03-2018 hmeg3_RS17540 951a5f90c187221e98e93978801e75af 256 Pfam PF01738 Dienelactone hydrolase family 46 252 1.2E-32 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 hmeg3_RS17540 951a5f90c187221e98e93978801e75af 256 Gene3D G3DSA:3.40.50.1820 59 253 1.3E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS17540 951a5f90c187221e98e93978801e75af 256 SUPERFAMILY SSF53474 31 253 2.01E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07930 9f03706f4df39a4a9678fdc78bde2f18 420 Pfam PF12704 MacB-like periplasmic core domain 21 193 7.6E-10 T 28-03-2018 IPR025857 MacB-like periplasmic core domain hmeg3_RS07930 9f03706f4df39a4a9678fdc78bde2f18 420 Pfam PF02687 FtsX-like permease family 318 410 2.9E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 hmeg3_RS16765 030dc47079102ef71d7a5332404841d3 209 Gene3D G3DSA:3.90.950.10 8 203 5.3E-51 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like hmeg3_RS16765 030dc47079102ef71d7a5332404841d3 209 Pfam PF02545 Maf-like protein 9 195 2.9E-41 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS16765 030dc47079102ef71d7a5332404841d3 209 SUPERFAMILY SSF52972 8 195 2.16E-53 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like hmeg3_RS16765 030dc47079102ef71d7a5332404841d3 209 Hamap MF_00528 Septum formation protein Maf [maf]. 9 200 28.012 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS16765 030dc47079102ef71d7a5332404841d3 209 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 194 1.9E-43 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS16765 030dc47079102ef71d7a5332404841d3 209 PIRSF PIRSF006305 1 200 5.8E-42 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 hmeg3_RS11265 f4fd49df54676f278282689d5bce55ba 248 Pfam PF02104 SURF1 family 3 217 4.4E-35 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS00850 ea535b8ef1a49774b7d6c745fecda384 221 Gene3D G3DSA:3.40.30.10 11 219 1.4E-27 T 28-03-2018 hmeg3_RS00850 ea535b8ef1a49774b7d6c745fecda384 221 SUPERFAMILY SSF52833 13 216 1.06E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS00850 ea535b8ef1a49774b7d6c745fecda384 221 Pfam PF01323 DSBA-like thioredoxin domain 97 196 3.5E-7 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 hmeg3_RS00725 76abdfc3a0509dbc0d412e1c519ca863 170 Pfam PF04093 rod shape-determining protein MreD 13 154 1.8E-15 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 hmeg3_RS00725 76abdfc3a0509dbc0d412e1c519ca863 170 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 12 155 9.0E-30 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 hmeg3_RS00725 76abdfc3a0509dbc0d412e1c519ca863 170 PIRSF PIRSF018472 5 164 5.1E-44 T 28-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type hmeg3_RS19625 60f2e0aaa23840779d8cbd758265c18a 567 Pfam PF08309 LVIVD repeat 347 371 0.017 T 28-03-2018 IPR013211 LVIVD hmeg3_RS18190 75c0f58161964c5717b220acae24ee8c 280 Gene3D G3DSA:2.40.160.20 22 222 2.0E-9 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS07305 9d00ce787d89b8d416abfcabce542afc 258 Pfam PF02698 DUF218 domain 80 243 1.4E-28 T 28-03-2018 IPR003848 Domain of unknown function DUF218 hmeg3_RS07305 9d00ce787d89b8d416abfcabce542afc 258 Gene3D G3DSA:3.40.50.620 71 216 5.1E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold hmeg3_RS14845 c69b2f9b76bc95dde643c11cf1aec8c8 118 Pfam PF09722 Protein of unknown function (DUF2384) 69 115 3.5E-11 T 28-03-2018 IPR024467 Domain of unknown function DUF2384 hmeg3_RS21745 64838cdc2d590d8da100d2604289f08b 177 Pfam PF08534 Redoxin 48 162 1.7E-16 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 hmeg3_RS21745 64838cdc2d590d8da100d2604289f08b 177 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 hmeg3_RS21745 64838cdc2d590d8da100d2604289f08b 177 SUPERFAMILY SSF52833 4 172 7.89E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS21745 64838cdc2d590d8da100d2604289f08b 177 Gene3D G3DSA:3.40.30.10 20 176 1.6E-30 T 28-03-2018 hmeg3_RS07635 580209f9df595ff7e136aa17d7ab95ab 297 SUPERFAMILY SSF103481 190 289 2.22E-10 T 28-03-2018 hmeg3_RS07635 580209f9df595ff7e136aa17d7ab95ab 297 Pfam PF00892 EamA-like transporter family 14 144 2.5E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS07635 580209f9df595ff7e136aa17d7ab95ab 297 Pfam PF00892 EamA-like transporter family 159 288 2.1E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS07635 580209f9df595ff7e136aa17d7ab95ab 297 SUPERFAMILY SSF103481 49 148 7.32E-11 T 28-03-2018 hmeg3_RS18060 e014d7ca32ec649651faf30567a30608 80 Gene3D G3DSA:1.20.5.1000 1 62 1.1E-6 T 28-03-2018 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 Pfam PF13609 Gram-negative porin 9 374 6.3E-50 T 28-03-2018 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00184 Neisseria sp. porin signature 347 371 7.8E-13 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00184 Neisseria sp. porin signature 62 87 7.8E-13 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00184 Neisseria sp. porin signature 162 179 7.8E-13 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 60 71 2.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 104 114 2.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 163 174 2.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 314 331 2.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 191 203 2.5E-7 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 SUPERFAMILY SSF56935 24 277 3.46E-75 T 28-03-2018 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 SUPERFAMILY SSF56935 305 404 3.46E-75 T 28-03-2018 hmeg3_RS01380 134b72444914d773deac29ef1c5c8875 404 Gene3D G3DSA:2.40.160.10 26 404 2.0E-74 T 28-03-2018 hmeg3_RS03030 c8f428f7803addde20a0e12918cf38df 403 Pfam PF06181 Urate oxidase N-terminal 3 301 2.0E-135 T 28-03-2018 IPR010389 Urate oxidase N-terminal hmeg3_RS03030 c8f428f7803addde20a0e12918cf38df 403 SUPERFAMILY SSF46626 300 400 5.59E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 hmeg3_RS13410 864dfd22d1c70824789d5f2a1de118c7 66 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 3.5E-19 T 28-03-2018 IPR012451 Protein of unknown function DUF1656 hmeg3_RS14735 061ba76d87a9a55d964771d7de6023e2 149 Gene3D G3DSA:1.20.5.320 38 143 0.0012 T 28-03-2018 hmeg3_RS10945 50974c49e74615c983baa9487d6ebddf 290 Gene3D G3DSA:1.10.3720.10 53 285 2.1E-20 T 28-03-2018 hmeg3_RS10945 50974c49e74615c983baa9487d6ebddf 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 274 2.7E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS10945 50974c49e74615c983baa9487d6ebddf 290 SUPERFAMILY SSF161098 84 271 1.96E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04730 f1bbcb7c519e56d9e659f6c991bc4bfd 133 Pfam PF04519 Polymer-forming cytoskeletal 13 112 7.8E-26 T 28-03-2018 IPR007607 Protein of unknown function DUF583 hmeg3_RS24315 9a0081de5358ef2302af9148c4b7e0ff 208 SUPERFAMILY SSF52540 4 183 2.99E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS24315 9a0081de5358ef2302af9148c4b7e0ff 208 Pfam PF00005 ABC transporter 25 162 4.8E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 hmeg3_RS24315 9a0081de5358ef2302af9148c4b7e0ff 208 Gene3D G3DSA:3.40.50.300 4 201 1.0E-31 T 28-03-2018 hmeg3_RS11705 7bb44e56c84052e9020d2c446cb5558b 191 Pfam PF05128 Domain of unknown function (DUF697) 23 174 4.4E-16 T 28-03-2018 IPR021147 Protein of unknown function DUF697 hmeg3_RS02140 7e61d4e8caeb27461524a335e73670a4 114 Pfam PF11604 Copper binding periplasmic protein CusF 46 112 3.1E-23 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF hmeg3_RS09310 dc0c6e0165aa15ef88923655ec2cbc01 168 PIRSF PIRSF004638 22 168 9.7E-26 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 hmeg3_RS09310 dc0c6e0165aa15ef88923655ec2cbc01 168 Pfam PF03653 Uncharacterised protein family (UPF0093) 27 168 2.1E-20 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 hmeg3_RS07375 e540fbcd1ab7524908ab61effb0a0b34 212 PIRSF PIRSF006324 2 212 3.0E-53 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS07375 e540fbcd1ab7524908ab61effb0a0b34 212 Pfam PF01810 LysE type translocator 12 209 1.4E-26 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS08450 aa9117e0e1ecf54f16687ce077d55255 123 SUPERFAMILY SSF103481 46 122 1.44E-11 T 28-03-2018 hmeg3_RS08450 aa9117e0e1ecf54f16687ce077d55255 123 Pfam PF00892 EamA-like transporter family 40 121 1.2E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 hmeg3_RS06140 369a273a64f20d3a03a3f82aa2d59534 286 Gene3D G3DSA:3.60.21.10 24 265 3.9E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS06140 369a273a64f20d3a03a3f82aa2d59534 286 SUPERFAMILY SSF56300 25 249 4.25E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like hmeg3_RS06140 369a273a64f20d3a03a3f82aa2d59534 286 Pfam PF00149 Calcineurin-like phosphoesterase 26 227 4.0E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 hmeg3_RS00390 9144a016be10fae93e57e1bcb0dcfdee 350 SUPERFAMILY SSF51735 6 201 7.01E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain hmeg3_RS00390 9144a016be10fae93e57e1bcb0dcfdee 350 Gene3D G3DSA:3.30.360.10 135 347 3.1E-47 T 28-03-2018 hmeg3_RS00390 9144a016be10fae93e57e1bcb0dcfdee 350 Gene3D G3DSA:3.40.50.720 2 134 8.4E-34 T 28-03-2018 hmeg3_RS00390 9144a016be10fae93e57e1bcb0dcfdee 350 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 118 3.4E-23 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 hmeg3_RS00390 9144a016be10fae93e57e1bcb0dcfdee 350 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 229 5.1E-16 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 hmeg3_RS20890 dd4f586ddc731326f51bb826be3a5887 119 Pfam PF03960 ArsC family 7 114 3.4E-18 T 28-03-2018 IPR006660 Arsenate reductase-like hmeg3_RS20890 dd4f586ddc731326f51bb826be3a5887 119 SUPERFAMILY SSF52833 3 117 2.69E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS20890 dd4f586ddc731326f51bb826be3a5887 119 Gene3D G3DSA:3.40.30.10 1 118 1.8E-40 T 28-03-2018 hmeg3_RS20890 dd4f586ddc731326f51bb826be3a5887 119 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 4.0E-41 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 hmeg3_RS10780 a805ff935e8527f8968f29ea9158866f 111 Gene3D G3DSA:3.30.70.100 12 104 3.2E-23 T 28-03-2018 hmeg3_RS10780 a805ff935e8527f8968f29ea9158866f 111 SUPERFAMILY SSF54909 6 108 1.85E-32 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel hmeg3_RS01330 aeb1655b5e766d3a1551825fec3f3c42 317 Gene3D G3DSA:1.10.3470.10 4 296 7.9E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01330 aeb1655b5e766d3a1551825fec3f3c42 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 292 9.0E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS18635 4d9c22bf50636f1075488c06360e5097 701 Pfam PF13515 Fusaric acid resistance protein-like 402 525 4.3E-23 T 28-03-2018 hmeg3_RS23970 639dde8161d1982775d8cc78ecfe5dd4 353 SUPERFAMILY SSF144052 88 352 7.59E-15 T 28-03-2018 hmeg3_RS08155 6ed3cef87286d5e7beb47cd7e625d6c3 265 SUPERFAMILY SSF52540 25 243 1.95E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase hmeg3_RS08155 6ed3cef87286d5e7beb47cd7e625d6c3 265 Gene3D G3DSA:3.40.50.300 8 246 2.1E-15 T 28-03-2018 hmeg3_RS20095 b315fe326ff33c63b8d5a389fa3076a9 270 Pfam PF03591 AzlC protein 56 197 8.0E-30 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease hmeg3_RS18605 9424528b4b9951e6225c4dbb6d83512e 250 SUPERFAMILY SSF52317 3 198 9.02E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS18605 9424528b4b9951e6225c4dbb6d83512e 250 Gene3D G3DSA:3.40.50.880 1 234 4.9E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like hmeg3_RS18605 9424528b4b9951e6225c4dbb6d83512e 250 Pfam PF00117 Glutamine amidotransferase class-I 22 184 2.2E-16 T 28-03-2018 IPR017926 Glutamine amidotransferase hmeg3_RS22795 49d31a5058ff50e4e516efa268241cd0 101 SUPERFAMILY SSF57716 2 101 5.35E-38 T 28-03-2018 hmeg3_RS22795 49d31a5058ff50e4e516efa268241cd0 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.969 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid hmeg3_RS22795 49d31a5058ff50e4e516efa268241cd0 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 1.8E-26 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 hmeg3_RS22795 49d31a5058ff50e4e516efa268241cd0 101 Gene3D G3DSA:4.10.830.10 1 101 1.6E-34 T 28-03-2018 hmeg3_RS09045 9f0760b0f1d739d967effb6cf2187d37 101 Pfam PF07769 psiF repeat 67 98 5.4E-17 T 28-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat hmeg3_RS09045 9f0760b0f1d739d967effb6cf2187d37 101 Pfam PF07769 psiF repeat 27 58 2.7E-17 T 28-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat hmeg3_RS00060 13eb60aab33c16ab105829c97da36b0a 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 217 3.0E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00060 13eb60aab33c16ab105829c97da36b0a 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 6.5E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS00060 13eb60aab33c16ab105829c97da36b0a 222 SUPERFAMILY SSF161098 15 208 1.31E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS00060 13eb60aab33c16ab105829c97da36b0a 222 Gene3D G3DSA:1.10.3720.10 1 222 3.5E-43 T 28-03-2018 hmeg3_RS14770 ce599e4977d2fa51c9ce6775b9e28283 113 Pfam PF11604 Copper binding periplasmic protein CusF 45 111 4.3E-23 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF hmeg3_RS09675 27f7643ea46d38b3be391083f8a280ed 119 Gene3D G3DSA:1.10.10.10 1 118 5.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS09675 27f7643ea46d38b3be391083f8a280ed 119 SUPERFAMILY SSF46785 42 110 1.63E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS08000 bef6fed4bf57d3fd701ed5797ec110f5 340 Gene3D G3DSA:3.40.190.10 146 340 2.3E-29 T 28-03-2018 hmeg3_RS08000 bef6fed4bf57d3fd701ed5797ec110f5 340 Pfam PF09084 NMT1/THI5 like 51 266 2.1E-33 T 28-03-2018 IPR015168 SsuA/THI5-like hmeg3_RS08000 bef6fed4bf57d3fd701ed5797ec110f5 340 Gene3D G3DSA:3.40.190.10 34 145 9.0E-11 T 28-03-2018 hmeg3_RS08000 bef6fed4bf57d3fd701ed5797ec110f5 340 SUPERFAMILY SSF53850 37 267 3.14E-26 T 28-03-2018 hmeg3_RS01535 005d7a6b528bae1ccec752cb483821f9 211 Pfam PF01810 LysE type translocator 16 208 3.5E-27 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS14270 a5e86ef1701b192a28589fe51d94f2f9 272 Pfam PF09992 Phosphodiester glycosidase 96 245 8.3E-22 T 28-03-2018 IPR018711 Phosphodiester glycosidase hmeg3_RS13135 8bd732179fa4e60ede46e22e9a445337 161 Pfam PF07681 DoxX 40 127 1.6E-18 T 28-03-2018 IPR032808 DoxX family hmeg3_RS14035 7d7279dc5d52cce28edab0c467b8125d 144 SUPERFAMILY SSF46785 15 126 1.1E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14035 7d7279dc5d52cce28edab0c467b8125d 144 Gene3D G3DSA:1.10.10.10 27 128 3.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain hmeg3_RS14035 7d7279dc5d52cce28edab0c467b8125d 144 Pfam PF01638 HxlR-like helix-turn-helix 29 115 1.1E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type hmeg3_RS16480 d44549eebe28eed02a0e9cfd9e24d794 130 Pfam PF09345 Domain of unknown function (DUF1987) 6 125 2.0E-42 T 28-03-2018 IPR018530 Domain of unknown function DUF1987 hmeg3_RS01700 df5762cc250e99110cea944aa6dbd2c2 134 Gene3D G3DSA:3.10.180.10 1 131 7.5E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS01700 df5762cc250e99110cea944aa6dbd2c2 134 SUPERFAMILY SSF54593 2 130 5.5E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS01700 df5762cc250e99110cea944aa6dbd2c2 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 6.6E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS09055 ab5263db86f54ee1c852dfcbae7ef214 118 Gene3D G3DSA:1.20.5.170 29 104 0.0011 T 28-03-2018 hmeg3_RS07840 b55b22b7a7870ff7ff441c9b76fee092 470 Pfam PF04932 O-Antigen ligase 222 377 3.3E-18 T 28-03-2018 IPR007016 O-antigen ligase-related hmeg3_RS12705 135e085384edb615dca4ad12c8fef0e3 340 SUPERFAMILY SSF53850 153 279 7.91E-5 T 28-03-2018 hmeg3_RS12705 135e085384edb615dca4ad12c8fef0e3 340 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 53 321 4.4E-44 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 hmeg3_RS12705 135e085384edb615dca4ad12c8fef0e3 340 Gene3D G3DSA:3.40.190.10 154 244 1.4E-4 T 28-03-2018 hmeg3_RS12535 dd683134ecdaccc54e66f82a8e8090c3 150 Pfam PF05425 Copper resistance protein D 46 143 3.1E-11 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 hmeg3_RS18505 04c3484c410078fe9da0bfd180401996 517 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 13 230 3.5E-72 T 28-03-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein hmeg3_RS18505 04c3484c410078fe9da0bfd180401996 517 SUPERFAMILY SSF48173 236 496 1.31E-60 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 hmeg3_RS18505 04c3484c410078fe9da0bfd180401996 517 Gene3D G3DSA:1.10.579.10 326 500 1.7E-30 T 28-03-2018 hmeg3_RS18505 04c3484c410078fe9da0bfd180401996 517 Gene3D G3DSA:1.25.40.80 139 325 4.2E-46 T 28-03-2018 hmeg3_RS19055 e4bc343f2b0e620fac43150411ea08d6 119 ProDom PD074011 PRECURSOR SIGNAL RESISTANCE CZCI ZINC COBALT-ZINC-CADMIUM SYSTEM COBALT CATION CADMIUM 1 119 2.0E-11 T 28-03-2018 IPR020487 Cobalt/zinc/cadmium resistance protein CzcI hmeg3_RS09230 539c19ec57940597248afffd22030124 421 Pfam PF02687 FtsX-like permease family 308 414 3.3E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 hmeg3_RS09230 539c19ec57940597248afffd22030124 421 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 8 421 5.1E-151 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 hmeg3_RS09230 539c19ec57940597248afffd22030124 421 Pfam PF12704 MacB-like periplasmic core domain 34 245 8.9E-21 T 28-03-2018 IPR025857 MacB-like periplasmic core domain hmeg3_RS22635 bec02b270bd33720fe2ac5ca2f8dd556 706 Pfam PF05140 ResB-like family 27 696 3.0E-164 T 28-03-2018 IPR007816 ResB-like domain hmeg3_RS20220 57506d4191e0bed34a931661b692683d 680 Pfam PF00474 Sodium:solute symporter family 498 613 4.9E-19 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS20220 57506d4191e0bed34a931661b692683d 680 Pfam PF00474 Sodium:solute symporter family 69 234 3.3E-32 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS20220 57506d4191e0bed34a931661b692683d 680 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 44 680 2.6E-226 T 28-03-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily hmeg3_RS21575 3bde45e069f722eab909e91336c50a79 279 Gene3D G3DSA:3.40.50.970 1 272 7.0E-62 T 28-03-2018 hmeg3_RS21575 3bde45e069f722eab909e91336c50a79 279 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 22 258 1.7E-42 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 hmeg3_RS21575 3bde45e069f722eab909e91336c50a79 279 SUPERFAMILY SSF52518 8 272 6.66E-77 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold hmeg3_RS04365 32c2974cecb32136729e80240ad98faa 163 Pfam PF09335 SNARE associated Golgi protein 53 142 9.6E-10 T 28-03-2018 IPR032816 SNARE associated Golgi protein hmeg3_RS13470 5c579c9ba275be6ce10a4a4d5f5e7c4d 215 Pfam PF01810 LysE type translocator 20 208 5.0E-29 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS13470 5c579c9ba275be6ce10a4a4d5f5e7c4d 215 PIRSF PIRSF006324 5 212 9.6E-52 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS07275 cdb128866e308505873a5c5be0b557e1 110 Pfam PF11162 Protein of unknown function (DUF2946) 1 107 2.1E-9 T 28-03-2018 IPR021333 Protein of unknown function DUF2946 hmeg3_RS04550 43fd00757aa4b5896a1cedba440358fe 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 212 3.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS04550 43fd00757aa4b5896a1cedba440358fe 227 Gene3D G3DSA:1.10.3720.10 2 222 6.9E-41 T 28-03-2018 hmeg3_RS04550 43fd00757aa4b5896a1cedba440358fe 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 2.2E-32 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 hmeg3_RS04550 43fd00757aa4b5896a1cedba440358fe 227 SUPERFAMILY SSF161098 14 202 2.22E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 Pfam PF00813 FliP family 59 250 1.4E-78 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 126 140 9.0E-31 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 54 63 9.0E-31 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 154 166 9.0E-31 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 244 254 9.0E-31 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 114 126 9.0E-31 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 176 188 9.0E-31 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 231 243 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 56 75 3.0E-63 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 75 95 3.0E-63 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 183 203 3.0E-63 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 95 114 3.0E-63 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 228 253 3.0E-63 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 204 225 3.0E-63 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 hmeg3_RS08270 43dce069caa564a72af9fb99a1eca67b 255 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 58 254 1.4E-89 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 hmeg3_RS14285 73657bb139abaf578c6d3f144477e284 230 Gene3D G3DSA:3.30.1380.10 25 177 3.4E-23 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 hmeg3_RS14285 73657bb139abaf578c6d3f144477e284 230 SUPERFAMILY SSF55166 28 179 1.41E-26 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 hmeg3_RS14285 73657bb139abaf578c6d3f144477e284 230 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 94 177 8.9E-21 T 28-03-2018 hmeg3_RS03345 292053c4da610b700db16b790c8900e6 307 Pfam PF02687 FtsX-like permease family 210 301 3.4E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 hmeg3_RS03345 292053c4da610b700db16b790c8900e6 307 PIRSF PIRSF003097 1 305 1.5E-60 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 hmeg3_RS17015 75f949e3452c8ba490947bab34d336b7 120 SUPERFAMILY SSF142906 1 116 3.79E-25 T 28-03-2018 hmeg3_RS17015 75f949e3452c8ba490947bab34d336b7 120 Pfam PF04237 YjbR 12 102 1.1E-13 T 28-03-2018 IPR007351 Uncharacterised protein YjbR hmeg3_RS17285 78b3e72dec391a7ff1feb0aad694c569 106 Pfam PF06127 Protein of unknown function (DUF962) 11 103 1.6E-36 T 28-03-2018 IPR009305 Protein of unknown function DUF962 hmeg3_RS21180 844083d295e6f8cf24e8b914d8612ea3 189 Pfam PF02397 Bacterial sugar transferase 5 182 9.1E-54 T 28-03-2018 IPR003362 Bacterial sugar transferase hmeg3_RS20255 2c71f716fd2b8d8a7e38c6b6a401797d 146 Pfam PF07883 Cupin domain 57 109 2.0E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel hmeg3_RS20255 2c71f716fd2b8d8a7e38c6b6a401797d 146 SUPERFAMILY SSF51182 31 137 5.94E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain hmeg3_RS20255 2c71f716fd2b8d8a7e38c6b6a401797d 146 Gene3D G3DSA:2.60.120.10 12 134 9.5E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold hmeg3_RS14215 47c2dd1f12c00727091a752ef3042a74 215 SUPERFAMILY SSF51197 19 213 5.77E-60 T 28-03-2018 hmeg3_RS14215 47c2dd1f12c00727091a752ef3042a74 215 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 21 212 1.1E-54 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like hmeg3_RS14215 47c2dd1f12c00727091a752ef3042a74 215 Gene3D G3DSA:2.60.120.590 14 215 6.2E-50 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like hmeg3_RS22180 1ac24e5563f39d4d9d944d6746af3f6c 204 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 134 175 1.2E-8 T 28-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 hmeg3_RS10305 663c4a36045de7bbd43da8e0543fbb01 273 Pfam PF05742 Transport and Golgi organisation 2 1 227 5.6E-62 T 28-03-2018 IPR008551 Transport and Golgi organisation protein 2 hmeg3_RS12880 cdc1e4eaf7ef5b3092cd354b2b6e63fd 410 SUPERFAMILY SSF103473 12 399 1.15E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS12880 cdc1e4eaf7ef5b3092cd354b2b6e63fd 410 Gene3D G3DSA:1.20.1250.20 211 403 5.4E-12 T 28-03-2018 hmeg3_RS12880 cdc1e4eaf7ef5b3092cd354b2b6e63fd 410 Gene3D G3DSA:1.20.1250.20 8 207 1.8E-22 T 28-03-2018 hmeg3_RS12880 cdc1e4eaf7ef5b3092cd354b2b6e63fd 410 Pfam PF05977 Transmembrane secretion effector 11 394 3.3E-38 T 28-03-2018 IPR010290 Transmembrane secretion effector hmeg3_RS18690 1d28b1b0fc04736449c6c1f17bb35b7b 353 SUPERFAMILY SSF53474 34 211 1.26E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS18690 1d28b1b0fc04736449c6c1f17bb35b7b 353 SUPERFAMILY SSF53474 242 332 1.26E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS18690 1d28b1b0fc04736449c6c1f17bb35b7b 353 Gene3D G3DSA:3.40.50.1820 28 345 3.4E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS20515 1da588b4e99673535b5ffc6144f5eaf8 139 Pfam PF07681 DoxX 13 94 7.0E-16 T 28-03-2018 IPR032808 DoxX family hmeg3_RS18460 b16fc69389dff9f2701e000251f9cb0c 65 TIGRFAM TIGR03510 XapX: XapX domain 6 51 9.4E-13 T 28-03-2018 IPR020017 XapX domain hmeg3_RS03665 99f31cafd90cad689d3875b808e7246c 195 SUPERFAMILY SSF55729 25 173 6.22E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase hmeg3_RS03665 99f31cafd90cad689d3875b808e7246c 195 TIGRFAM TIGR04045 MSMEG_0567_GNAT: putative N-acetyltransferase, MSMEG_0567 N-terminal domain family 26 176 4.6E-67 T 28-03-2018 IPR024035 GNAT N-acetyltransferase, putative hmeg3_RS03665 99f31cafd90cad689d3875b808e7246c 195 Gene3D G3DSA:3.40.630.30 22 174 5.8E-26 T 28-03-2018 hmeg3_RS01695 939712a5ffd6d8e8e134d0f1c9dc934a 275 Gene3D G3DSA:3.60.110.10 5 273 2.0E-59 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS01695 939712a5ffd6d8e8e134d0f1c9dc934a 275 Pfam PF00795 Carbon-nitrogen hydrolase 17 261 1.0E-35 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS01695 939712a5ffd6d8e8e134d0f1c9dc934a 275 SUPERFAMILY SSF56317 15 271 5.36E-58 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 hmeg3_RS17885 fd6caf215b057fa03c88f15a6ddfc0cf 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 270 2.3E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17885 fd6caf215b057fa03c88f15a6ddfc0cf 283 SUPERFAMILY SSF161098 79 261 3.92E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 hmeg3_RS17885 fd6caf215b057fa03c88f15a6ddfc0cf 283 Gene3D G3DSA:1.10.3720.10 13 276 1.4E-23 T 28-03-2018 hmeg3_RS20635 7ad893cbd598b42b22a4d6d92e54b90a 329 PIRSF PIRSF026166 1 328 1.7E-119 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter hmeg3_RS20635 7ad893cbd598b42b22a4d6d92e54b90a 329 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 7 314 5.0E-86 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter hmeg3_RS01370 f2639a13789d062be40bb2bccabcdd24 80 SUPERFAMILY SSF143120 1 76 7.32E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM hmeg3_RS11735 b804658087f3c25a955a3dc8eabbeff8 146 Pfam PF05128 Domain of unknown function (DUF697) 13 121 1.3E-9 T 28-03-2018 IPR021147 Protein of unknown function DUF697 hmeg3_RS15745 5190b19766056e22f1f72afcb14206c6 498 Pfam PF09480 Type III secretion system protein PrgH-EprH (PrgH) 113 494 1.5E-104 T 28-03-2018 IPR019029 Type III secretion system, PrgH/EprH-like GO:0016021 hmeg3_RS15745 5190b19766056e22f1f72afcb14206c6 498 TIGRFAM TIGR02554 PrgH: type III secretion apparatus protein PrgH/EprH 112 496 6.8E-95 T 28-03-2018 IPR013387 Type III secretion system, PrgH/EprH hmeg3_RS18445 2349b22118b17b93e15755f1ee4b7567 223 Pfam PF06912 Protein of unknown function (DUF1275) 1 206 2.7E-31 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 hmeg3_RS05260 729be51ed08871d3a52509d18a8ea6b4 195 Gene3D G3DSA:3.10.450.50 4 137 1.3E-4 T 28-03-2018 hmeg3_RS20990 6979633706ce99fa632deb3992fedce0 91 Pfam PF13663 Domain of unknown function (DUF4148) 1 57 3.6E-10 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS09035 c4ac6e732d13f4ab1d229db6a0179342 51 Pfam PF11295 Protein of unknown function (DUF3096) 9 44 2.9E-19 T 28-03-2018 IPR021446 Protein of unknown function DUF3096 hmeg3_RS08720 90c49902b8463cb741dda92892563ae6 408 Pfam PF11062 Protein of unknown function (DUF2863) 6 407 6.8E-159 T 28-03-2018 IPR021292 Protein of unknown function DUF2863 hmeg3_RS00640 3eabcbbe9c8b2410ad032da5fec143a4 158 Pfam PF04361 Protein of unknown function (DUF494) 1 151 5.6E-52 T 28-03-2018 IPR007456 Smg hmeg3_RS00640 3eabcbbe9c8b2410ad032da5fec143a4 158 Hamap MF_00598 Protein Smg [smg]. 1 158 26.07 T 28-03-2018 IPR007456 Smg hmeg3_RS04825 5ad8e3e747279277bfa3465f1a9f54fb 542 Gene3D G3DSA:2.160.20.70 263 347 8.6E-10 T 28-03-2018 hmeg3_RS04825 5ad8e3e747279277bfa3465f1a9f54fb 542 Pfam PF03961 Flagellar Assembly Protein A 85 537 2.3E-97 T 28-03-2018 IPR005646 Flagellar assembly protein A hmeg3_RS19010 d6344f635ccc7e0974d00277d3ad25aa 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 312 1.9E-45 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19010 d6344f635ccc7e0974d00277d3ad25aa 343 Gene3D G3DSA:1.10.3470.10 32 318 1.1E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS22390 52e66fdfb0d6c3dea5ea85d32f1138a4 169 SUPERFAMILY SSF55811 9 160 1.9E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 hmeg3_RS22390 52e66fdfb0d6c3dea5ea85d32f1138a4 169 Pfam PF00293 NUDIX domain 9 154 2.7E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 hmeg3_RS22390 52e66fdfb0d6c3dea5ea85d32f1138a4 169 Gene3D G3DSA:3.90.79.10 1 163 3.3E-27 T 28-03-2018 hmeg3_RS15085 ccb9d31e2289176a9297bffb8e79150a 393 PIRSF PIRSF015557 10 390 1.2E-142 T 28-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 hmeg3_RS15085 ccb9d31e2289176a9297bffb8e79150a 393 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 17 387 2.3E-144 T 28-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 hmeg3_RS15085 ccb9d31e2289176a9297bffb8e79150a 393 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 17 387 5.2E-145 T 28-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 hmeg3_RS05510 dc8e64ffbb853ff57a506a31ae9845ea 154 Pfam PF10027 Predicted integral membrane protein (DUF2269) 5 153 2.3E-31 T 28-03-2018 IPR018729 Protein of unknown function DUF2269, transmembrane hmeg3_RS05720 64891d54ad5cd037fb38a2c9508a0094 193 Pfam PF07209 Protein of unknown function (DUF1415) 12 180 2.9E-71 T 28-03-2018 IPR009858 Protein of unknown function DUF1415 hmeg3_RS23825 a7bce48011117d1ee060f9a598dbb93b 157 Gene3D G3DSA:1.10.1200.20 76 157 4.7E-10 T 28-03-2018 IPR000290 Colicin immunity protein/pyocin immunity protein GO:0015643|GO:0030153 hmeg3_RS00540 c45676e092222ab1d4d0ba702d86f526 231 Pfam PF12697 Alpha/beta hydrolase family 5 220 2.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 hmeg3_RS00540 c45676e092222ab1d4d0ba702d86f526 231 Gene3D G3DSA:3.40.50.1820 4 230 8.5E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS00540 c45676e092222ab1d4d0ba702d86f526 231 SUPERFAMILY SSF53474 4 226 7.97E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS06610 40d4cc214a4359085e8833c8b4739791 146 Pfam PF02643 Uncharacterized ACR, COG1430 40 142 1.8E-31 T 28-03-2018 IPR003795 Protein of unknown function DUF192 hmeg3_RS01165 2504ec49ff7d43224bfb75a2dbf7cd26 288 Gene3D G3DSA:1.10.3470.10 2 288 3.1E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01165 2504ec49ff7d43224bfb75a2dbf7cd26 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 276 9.7E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS20500 6795c5250b3be49149cd41e4bad72104 140 PIRSF PIRSF004638 1 140 1.8E-50 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 hmeg3_RS20500 6795c5250b3be49149cd41e4bad72104 140 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 140 3.6E-45 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 hmeg3_RS14575 45298e73decd7a5ce2cba4204a73efe0 473 Pfam PF16980 Putative citrate transport 31 472 6.2E-200 T 28-03-2018 IPR031566 Putative citrate transporter hmeg3_RS15725 592aaa7f331520b8675d50c0b2626cc8 225 Pfam PF09482 Bacterial type III secretion apparatus protein (OrgA_MxiK) 40 220 1.6E-27 T 28-03-2018 IPR013388 Type III secretion apparatus protein OrgA/MxiK GO:0009405 hmeg3_RS02680 9ac84942446ea687d2d4adf49bbc8e5b 156 SUPERFAMILY SSF55961 1 150 1.32E-40 T 28-03-2018 hmeg3_RS02680 9ac84942446ea687d2d4adf49bbc8e5b 156 Pfam PF08982 Domain of unknown function (DUF1857) 7 153 2.6E-33 T 28-03-2018 IPR015075 Acetylaranotin biosynthesis cluster protein L hmeg3_RS02680 9ac84942446ea687d2d4adf49bbc8e5b 156 Gene3D G3DSA:3.30.530.20 2 154 7.0E-39 T 28-03-2018 IPR023393 START-like domain hmeg3_RS05125 32158428840a4f79cb9bada2fa843c61 59 Pfam PF11755 Protein of unknown function (DUF3311) 4 51 5.3E-20 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 hmeg3_RS08595 4e5d531d5275c17dee3e97de8d8da1de 258 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 36.233 T 28-03-2018 IPR005583 Peroxide stress protein YaaA hmeg3_RS08595 4e5d531d5275c17dee3e97de8d8da1de 258 Pfam PF03883 Peroxide stress protein YaaA 1 242 3.5E-91 T 28-03-2018 IPR005583 Peroxide stress protein YaaA hmeg3_RS07655 3cfbef08baf6c1c814f4ef681fadb017 173 Pfam PF07105 Protein of unknown function (DUF1367) 86 141 3.8E-6 T 28-03-2018 IPR009797 Protein of unknown function DUF1367 hmeg3_RS16380 47385f1882363d17087a9384a80a7332 140 Gene3D G3DSA:3.10.180.10 1 131 6.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS16380 47385f1882363d17087a9384a80a7332 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 128 8.7E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS16380 47385f1882363d17087a9384a80a7332 140 SUPERFAMILY SSF54593 4 130 5.24E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS05120 44ed25d0dc490ac7256aed7cf490254a 500 Pfam PF00474 Sodium:solute symporter family 48 435 1.4E-21 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 hmeg3_RS07630 8a73183a056771ae885f1251ed1731ad 196 Pfam PF01810 LysE type translocator 14 185 6.3E-12 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS21690 e79d95f5074177c2e5539b6b7165001e 151 Pfam PF05433 Glycine zipper 2TM domain 63 104 3.4E-10 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 hmeg3_RS06515 21941b4b0e711ec23c676c20e293e6be 135 SUPERFAMILY SSF143744 2 134 8.24E-38 T 28-03-2018 hmeg3_RS06515 21941b4b0e711ec23c676c20e293e6be 135 Pfam PF03928 Haem-degrading 7 130 8.5E-33 T 28-03-2018 IPR005624 Haem-degrading hmeg3_RS15040 2e0e4ae767e7e49c76d450fd22170f09 213 Pfam PF11066 Protein of unknown function (DUF2867) 64 207 7.3E-33 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 hmeg3_RS01325 892ef93f875107ec246445be2b3d5280 304 Gene3D G3DSA:1.10.3470.10 1 297 2.3E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS01325 892ef93f875107ec246445be2b3d5280 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 292 3.1E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS07575 cfe0cef920fae60710c1b3bc11661f6f 168 Pfam PF13515 Fusaric acid resistance protein-like 32 152 1.9E-15 T 28-03-2018 hmeg3_RS02565 c26fd68ad787a1f0f31427c904bb1f66 509 Pfam PF04293 SpoVR like protein 15 446 2.2E-174 T 28-03-2018 IPR007390 Sporulation stage V, protein R hmeg3_RS23870 0faa8ced98812b0a19290a791417b906 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 126 5.3E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain hmeg3_RS23870 0faa8ced98812b0a19290a791417b906 138 Gene3D G3DSA:3.10.180.10 1 135 8.5E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS23870 0faa8ced98812b0a19290a791417b906 138 SUPERFAMILY SSF54593 2 129 3.16E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS18920 17e0886291ea6367be5ec6317d515746 405 Pfam PF04932 O-Antigen ligase 173 329 2.6E-12 T 28-03-2018 IPR007016 O-antigen ligase-related hmeg3_RS18140 a22defb1ac51cc4cfee458d73e435470 427 Pfam PF11299 Protein of unknown function (DUF3100) 15 255 2.3E-93 T 28-03-2018 IPR021450 Protein of unknown function DUF3100 hmeg3_RS21950 93d3f7ccc4bfb6b9adbeaa04d7f0113e 245 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 106 229 2.1E-21 T 28-03-2018 IPR019262 Domain of unknown function DUF2272 hmeg3_RS04130 fdfc4f6d8dbfcf34895ffa758a34e57d 211 Gene3D G3DSA:2.40.50.140 19 135 5.1E-9 T 28-03-2018 hmeg3_RS06735 7c6ae1e48bff541133b8e8ff901146a6 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 287 6.7E-29 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS06735 7c6ae1e48bff541133b8e8ff901146a6 306 Gene3D G3DSA:1.10.3470.10 1 290 1.4E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS11390 7f5f0dda02472d9b4cf4210f46bf8d6a 183 Gene3D G3DSA:3.40.1550.10 1 169 1.2E-4 T 28-03-2018 IPR028976 CheC-like domain hmeg3_RS19575 e49d57e5a98f259e452f8e992b7e8a32 143 SUPERFAMILY SSF55298 14 142 5.34E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS19575 e49d57e5a98f259e452f8e992b7e8a32 143 Pfam PF01042 Endoribonuclease L-PSP 17 140 7.2E-27 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family hmeg3_RS19575 e49d57e5a98f259e452f8e992b7e8a32 143 Gene3D G3DSA:3.30.1330.40 8 143 1.5E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like hmeg3_RS03200 c9d276cc812af442b99cace586ad5e5d 246 Pfam PF11104 Type IV pilus assembly protein PilM; 207 245 4.0E-8 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM hmeg3_RS03200 c9d276cc812af442b99cace586ad5e5d 246 Pfam PF11104 Type IV pilus assembly protein PilM; 17 187 2.5E-34 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM hmeg3_RS03200 c9d276cc812af442b99cace586ad5e5d 246 Gene3D G3DSA:3.30.420.40 174 246 0.0032 T 28-03-2018 hmeg3_RS03200 c9d276cc812af442b99cace586ad5e5d 246 Gene3D G3DSA:3.30.420.40 1 173 3.1E-21 T 28-03-2018 hmeg3_RS13990 8c05bb3991e51a16d987aa0147358e7d 107 Gene3D G3DSA:1.20.120.20 15 107 5.0E-8 T 28-03-2018 hmeg3_RS07240 7f6ed44dc6e967af14226fe361f9565d 532 Gene3D G3DSA:1.20.1250.20 19 207 1.4E-31 T 28-03-2018 hmeg3_RS07240 7f6ed44dc6e967af14226fe361f9565d 532 Pfam PF07690 Major Facilitator Superfamily 27 421 2.7E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 hmeg3_RS07240 7f6ed44dc6e967af14226fe361f9565d 532 Gene3D G3DSA:1.20.1250.20 263 525 1.5E-30 T 28-03-2018 hmeg3_RS07240 7f6ed44dc6e967af14226fe361f9565d 532 SUPERFAMILY SSF103473 24 213 9.81E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07240 7f6ed44dc6e967af14226fe361f9565d 532 SUPERFAMILY SSF103473 488 515 9.81E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS07240 7f6ed44dc6e967af14226fe361f9565d 532 SUPERFAMILY SSF103473 260 431 9.81E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain hmeg3_RS10265 51904b78ead2bcaa1349b476ba63e021 433 Pfam PF03600 Citrate transporter 16 364 8.6E-41 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 hmeg3_RS10265 51904b78ead2bcaa1349b476ba63e021 433 TIGRFAM TIGR00784 citMHS: citrate transporter 1 430 4.1E-121 T 28-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 hmeg3_RS10735 c821a9199f16f3035159da7cd77cb772 373 Pfam PF04116 Fatty acid hydroxylase superfamily 83 216 6.9E-30 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 hmeg3_RS20065 63d81de98821f1f71a73105e82a22231 63 Pfam PF04886 PT repeat 5 38 6.8E-10 T 28-03-2018 IPR006970 PT repeat hmeg3_RS08295 8706299589d771797840d5dd039e1d0b 411 Pfam PF02120 Flagellar hook-length control protein FliK 285 368 7.7E-25 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal hmeg3_RS07900 6ed152dd7e9cd25a3a2d320f863254aa 203 Gene3D G3DSA:2.40.50.140 16 194 3.5E-10 T 28-03-2018 hmeg3_RS24130 270bc2e25e92a60a5d5852490fd43a51 262 Pfam PF11678 Protein of unknown function (DUF3274) 155 215 6.4E-5 T 28-03-2018 IPR021692 Protein of unknown function DUF3274 hmeg3_RS23375 b35c2e0844b6d48d1ece171a9f6b7caf 91 Pfam PF13663 Domain of unknown function (DUF4148) 1 60 3.2E-13 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS15465 3b5fca82ebc69260d2a59ee98cde71a9 167 Gene3D G3DSA:1.20.5.50 91 167 7.8E-4 T 28-03-2018 hmeg3_RS24595 91e247ad58ccfa83b14f389b015c0374 412 Pfam PF11062 Protein of unknown function (DUF2863) 60 278 3.2E-10 T 28-03-2018 IPR021292 Protein of unknown function DUF2863 hmeg3_RS08085 15d3abb18d4aaf9e286aa3ec5f5c11b4 127 Pfam PF04248 Domain of unknown function (DUF427) 25 116 8.2E-34 T 28-03-2018 IPR007361 Domain of unknown function DUF427 hmeg3_RS04865 f0d19a27ea6dbbcb4d91ea2cac7931b9 188 Gene3D G3DSA:3.30.1330.80 40 188 2.0E-13 T 28-03-2018 hmeg3_RS04865 f0d19a27ea6dbbcb4d91ea2cac7931b9 188 SUPERFAMILY SSF117856 37 180 2.59E-12 T 28-03-2018 hmeg3_RS10135 57657a94a9992a6fd1c7a5419c7724ca 198 Pfam PF07273 Protein of unknown function (DUF1439) 50 173 1.9E-13 T 28-03-2018 IPR010835 Protein of unknown function DUF1439 hmeg3_RS14925 82002cf10f148bf5f6c3cdfb5d1410e4 369 Pfam PF05987 Bacterial protein of unknown function (DUF898) 34 362 1.8E-111 T 28-03-2018 IPR010295 Protein of unknown function DUF898 hmeg3_RS07830 91608676f3917c9352398944f36bdacf 448 Gene3D G3DSA:2.40.160.20 272 422 5.5E-7 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 hmeg3_RS02195 2010d4df57a91a817011f56419bbc197 116 Pfam PF13663 Domain of unknown function (DUF4148) 1 75 3.2E-13 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 hmeg3_RS10880 9575c6a4018f01f8c645e60d6dea7553 126 Pfam PF07681 DoxX 9 90 7.2E-18 T 28-03-2018 IPR032808 DoxX family hmeg3_RS19970 86274473ec29446457e08d0fc04a93dc 106 Gene3D G3DSA:1.10.357.10 3 104 5.5E-4 T 28-03-2018 hmeg3_RS12935 0301346d1b4de5aaf9efc54588db25ee 253 Pfam PF01925 Sulfite exporter TauE/SafE 12 249 1.4E-44 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS09765 85b4786e3663c2ab05e1479308d72efc 143 Gene3D G3DSA:3.40.30.10 3 123 1.1E-14 T 28-03-2018 hmeg3_RS09765 85b4786e3663c2ab05e1479308d72efc 143 Pfam PF00085 Thioredoxin 17 86 4.4E-9 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 hmeg3_RS09765 85b4786e3663c2ab05e1479308d72efc 143 SUPERFAMILY SSF52833 10 86 8.2E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold hmeg3_RS03315 7619a3091c5d2f1512654c815a3e5b4e 239 Pfam PF02104 SURF1 family 17 223 3.2E-37 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 hmeg3_RS01880 5f217652dface1e7eb2deab0a46e1adc 188 Gene3D G3DSA:3.40.50.1820 1 177 3.2E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold hmeg3_RS07825 a9ef3b892afb2a9f009c6882919cce13 385 Pfam PF01757 Acyltransferase family 27 360 2.8E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 hmeg3_RS14140 da1e0d8cdb450f511453ed2087884da4 214 Pfam PF16357 Putative PepSY_TM-like 18 214 5.1E-88 T 28-03-2018 IPR032307 Putative PepSY TM-like protein hmeg3_RS05005 5550b1a7da4c12109e973fc5b4f03b68 122 Gene3D G3DSA:3.10.180.10 10 122 2.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS05005 5550b1a7da4c12109e973fc5b4f03b68 122 SUPERFAMILY SSF54593 15 119 4.13E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase hmeg3_RS15500 a6b30b3254077011973e1c75e39f6e4c 500 Pfam PF08811 Protein of unknown function (DUF1800) 34 498 3.8E-144 T 28-03-2018 IPR014917 Protein of unknown function DUF1800 hmeg3_RS12345 a6c6bb0423cf51444a2d28a448f80cd6 241 Pfam PF01925 Sulfite exporter TauE/SafE 8 235 3.9E-30 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 hmeg3_RS05880 45be4696e2dcb8b49a2b3d4c79b623b8 360 Pfam PF01699 Sodium/calcium exchanger protein 216 357 5.9E-14 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 hmeg3_RS05880 45be4696e2dcb8b49a2b3d4c79b623b8 360 Pfam PF01699 Sodium/calcium exchanger protein 33 185 1.9E-15 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 hmeg3_RS12440 6f74edff977404313c3f4509357e4309 1380 Pfam PF02514 CobN/Magnesium Chelatase 131 1354 0.0 T 28-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 hmeg3_RS14085 270fbe528423e6220deb2ff89feb883c 242 Pfam PF13852 Protein of unknown function (DUF4197) 41 239 2.0E-71 T 28-03-2018 IPR025245 Protein of unknown function DUF4197 hmeg3_RS16010 dd2d4c62b7bfdff69b1c07ae01c7c0b5 114 Pfam PF12112 Protein of unknown function (DUF3579) 13 102 3.3E-38 T 28-03-2018 IPR021969 Protein of unknown function DUF3579 hmeg3_RS24385 3e31c43ca6b5bb93f5f059ee1ea13ac3 612 Gene3D G3DSA:3.40.50.2000 399 584 9.6E-11 T 28-03-2018 hmeg3_RS05380 40c29d41c50f8c62566087e992d4e8bb 189 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 6.8E-30 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 hmeg3_RS18660 2de9043bd3c71f8b77c111c7c3854afd 457 Pfam PF03631 Virulence factor BrkB 187 441 1.9E-49 T 28-03-2018 IPR017039 Virulence factor BrkB hmeg3_RS18195 18d2f7929851bcc39dd28bf9b7a213e0 52 Pfam PF11752 Protein of unknown function (DUF3309) 4 52 7.3E-24 T 28-03-2018 IPR021738 Protein of unknown function DUF3309 hmeg3_RS03680 db55b15c0e2580f67d8b3a2d554be617 95 TIGRFAM TIGR04042 MSMEG_0570_fam: MSMEG_0570 family protein 2 90 9.7E-40 T 28-03-2018 IPR023846 Conserved hypothetical protein CHP04042, MSMEG0570 hmeg3_RS04435 5a79a4c39e4805673129c40dd0eda459 210 PIRSF PIRSF006324 1 209 1.5E-52 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS04435 5a79a4c39e4805673129c40dd0eda459 210 Pfam PF01810 LysE type translocator 16 207 4.6E-38 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 hmeg3_RS19755 a5d826e7d05ea0eb11b4b80d3b9daa49 215 Pfam PF09335 SNARE associated Golgi protein 48 173 3.5E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein hmeg3_RS07590 4a1a5b45f416bfc5ca6d3dd1a4d1b28d 257 Gene3D G3DSA:3.30.1330.60 73 247 6.9E-4 T 28-03-2018 IPR006665 OmpA-like domain hmeg3_RS21055 ecec2155fccf35f6fd1b771655aa2974 350 Gene3D G3DSA:1.10.3470.10 37 350 9.0E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like hmeg3_RS21055 ecec2155fccf35f6fd1b771655aa2974 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 340 1.6E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 hmeg3_RS19660 6a26ec5183def67fc1ee903002991f0b 142 Gene3D G3DSA:1.10.260.40 3 85 6.1E-7 T 28-03-2018 hmeg3_RS13150 b673e825321751aae473bd5cdf1dcf3e 92 Pfam PF10048 Predicted integral membrane protein (DUF2282) 35 88 2.8E-25 T 28-03-2018 IPR018740 Protein of unknown function DUF2282, integral membrane hmeg3_RS09915 61305135bf0e001775ca5bd2ab4496eb 167 Pfam PF08909 Domain of unknown function (DUF1854) 37 166 2.6E-51 T 28-03-2018 IPR015005 Domain of unknown function DUF1854 hmeg3_RS18515 5ee96045da761b56e51ca292c4c9e69d 152 SUPERFAMILY SSF54637 6 151 8.8E-37 T 28-03-2018 IPR029069 HotDog domain hmeg3_RS18515 5ee96045da761b56e51ca292c4c9e69d 152 Pfam PF01575 MaoC like domain 13 111 1.7E-17 T 28-03-2018 IPR002539 MaoC-like domain hmeg3_RS18515 5ee96045da761b56e51ca292c4c9e69d 152 Gene3D G3DSA:3.10.129.10 1 148 1.5E-32 T 28-03-2018 hmeg3_RS05895 6744cefd83d490ba4a66044b5f1ca375 60 Pfam PF09791 Oxidoreductase-like protein, N-terminal 11 50 4.2E-13 T 28-03-2018 IPR019180 Oxidoreductase-like, N-terminal hmeg3_RS09390 9a70f9e1e14e6b8ed8636ea37ea7d5cc 289 Pfam PF03239 Iron permease FTR1 family 3 276 6.4E-27 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 hmeg3_RS02095 32acef7d34ef1de79bd8c23efdf916d3 296 Pfam PF13280 WYL domain 129 212 3.7E-10 T 28-03-2018 IPR026881 WYL domain hmeg3_RS02095 32acef7d34ef1de79bd8c23efdf916d3 296 PIRSF PIRSF015558 2 278 3.8E-59 T 28-03-2018 IPR016634 WYL domain protein, s026 type hmeg3_RS02555 4e971bc701a2d8ee71567e5b2706ee6e 226 Pfam PF01914 MarC family integral membrane protein 9 217 1.5E-37 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 hmeg3_RS02555 4e971bc701a2d8ee71567e5b2706ee6e 226 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 7 213 1.4E-32 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 hmeg3_RS09140 af6faf31b0ccea3911866116ad208061 472 Pfam PF11737 Protein of unknown function (DUF3300) 36 280 5.9E-89 T 28-03-2018 IPR021728 Protein of unknown function DUF3300 hmeg3_RS11890 d86f0243cd6f903b66d31de7f7524f22 133 Gene3D G3DSA:2.10.260.10 96 130 5.8E-5 T 28-03-2018 hmeg3_RS16760 12269bd4d82ff1746a2b18ac3d90e440 175 Pfam PF02620 Uncharacterized ACR, COG1399 68 174 2.6E-18 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD hmeg3_RS07170 1f49bf4e83fd3eefe4d17ea077dddc60 280 Pfam PF04536 TPM domain 38 164 2.7E-31 T 28-03-2018 IPR007621 TPM domain hmeg3_RS13945 fb66bf5c780eaec0d41a50c389138a9b 248 Pfam PF04402 Protein of unknown function (DUF541) 36 238 3.6E-24 T 28-03-2018 IPR007497 Protein of unknown function DUF541 hmeg3_RS13970 13dda476b6b7248ee8a999eea82a9cdb 136 Pfam PF12279 Protein of unknown function (DUF3619) 5 133 9.3E-40 T 28-03-2018 IPR022064 Protein of unknown function DUF3619 hmeg3_RS05835 6af1c5cf1783eb93e844477346debdea 58 SUPERFAMILY SSF51604 22 54 6.41E-5 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS05835 6af1c5cf1783eb93e844477346debdea 58 Gene3D G3DSA:3.20.20.120 5 58 4.3E-4 T 28-03-2018 IPR029065 Enolase C-terminal domain-like hmeg3_RS06960 22f03609114b9e94548c70baf8707181 216 Pfam PF04403 Paraquat-inducible protein A 46 197 2.3E-46 T 28-03-2018 IPR007498 Paraquat-inducible protein A hmeg3_RS02650 1cc708c8eea680b48405c2222faebdb2 70 Gene3D G3DSA:1.20.5.300 4 51 3.9E-15 T 28-03-2018 hmeg3_RS02650 1cc708c8eea680b48405c2222faebdb2 70 Pfam PF04102 SlyX 4 70 7.2E-22 T 28-03-2018 IPR007236 SlyX hmeg3_RS23330 66b128215ce6491e8dddd9288c849dac 87 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 3 74 5.7E-25 T 28-03-2018 IPR018680 Protein of unknown function DUF2164 hmeg3_RS19515 8a4bd9711a46830bc8a3acfab67fbf3a 402 Pfam PF00999 Sodium/hydrogen exchanger family 20 388 4.5E-21 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 hmeg3_RS11425 932cb8199f2a88da17af750af50cc3f4 181 Pfam PF11911 Protein of unknown function (DUF3429) 46 178 3.7E-28 T 28-03-2018 IPR021836 Protein of unknown function DUF3429 hmeg3_RS19820 d5d3329b0c0828a49d35b8b714a1ff42 57 Pfam PF13490 Putative zinc-finger 3 36 7.6E-6 T 28-03-2018 IPR027383 Putative zinc-finger hmeg3_RS16165 4928ec99b0d86cab6249c90d6218d2fc 651 Pfam PF13520 Amino acid permease 63 443 1.5E-16 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 hmeg3_RS11575 83de72f5d47d9f33733b0bb62f1149ca 263 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 12 233 7.5E-49 T 28-03-2018 hmeg3_RS18255 ce6ccf43e24e45478fc54932cc7d3b75 103 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 99 1.6E-22 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB hmeg3_RS20995 310992321cfecd52fd8866b1ecd1a265 81 Gene3D G3DSA:3.40.50.720 2 68 6.0E-4 T 28-03-2018 hmeg3_RS09175 a80c9f4a96b793680da6d9e07b289038 643 Pfam PF05787 Bacterial protein of unknown function (DUF839) 204 550 1.4E-17 T 28-03-2018 IPR008557 Protein of unknown function DUF839 hmeg3_RS02190 2ccef5839b977b593ac3814b639adee3 118 ProDom PD074011 PRECURSOR SIGNAL RESISTANCE CZCI ZINC COBALT-ZINC-CADMIUM SYSTEM COBALT CATION CADMIUM 1 118 3.0E-11 T 28-03-2018 IPR020487 Cobalt/zinc/cadmium resistance protein CzcI hmeg3_RS11615 e13167d474131da5919f06a831013f97 172 Pfam PF05751 FixH 13 153 8.1E-36 T 28-03-2018 IPR008620 Nitrogen fixation protein FixH hmeg3_RS08165 cff47e60e105721574bc54bba4d3d5e5 248 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 219 3.6E-25 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 hmeg3_RS13670 bd4540fabc7c2329b335ea340659fc8b 395 Pfam PF03235 Protein of unknown function DUF262 12 145 5.1E-13 T 28-03-2018 IPR004919 Domain of unknown function DUF262