HVS_RS00405 3525ba458f2b7a786fe6b17f4e98f096 327 Gene3D G3DSA:3.20.20.100 1 327 3.2E-78 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS00405 3525ba458f2b7a786fe6b17f4e98f096 327 SUPERFAMILY SSF51430 1 319 2.1E-79 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS00405 3525ba458f2b7a786fe6b17f4e98f096 327 PRINTS PR00069 Aldo-keto reductase signature 137 154 5.6E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS00405 3525ba458f2b7a786fe6b17f4e98f096 327 PRINTS PR00069 Aldo-keto reductase signature 42 66 5.6E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS00405 3525ba458f2b7a786fe6b17f4e98f096 327 PRINTS PR00069 Aldo-keto reductase signature 105 123 5.6E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS00405 3525ba458f2b7a786fe6b17f4e98f096 327 Pfam PF00248 Aldo/keto reductase family 16 315 2.8E-66 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS00610 120432a0eb23d2c7dc400294dd917087 369 Gene3D G3DSA:3.90.1720.10 197 367 5.4E-13 T 29-03-2018 HVS_RS00610 120432a0eb23d2c7dc400294dd917087 369 Pfam PF12671 Putative amidase domain 207 364 1.4E-45 T 29-03-2018 IPR024301 Putative amidase domain HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Pfam PF12836 Helix-hairpin-helix motif 480 544 6.2E-30 T 29-03-2018 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Gene3D G3DSA:3.30.420.140 317 459 3.9E-58 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SMART SM00316 644 715 4.7E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SUPERFAMILY SSF47781 459 547 5.0E-29 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Gene3D G3DSA:1.10.3500.10 109 316 8.7E-67 T 29-03-2018 IPR023323 Tex-like domain HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SUPERFAMILY SSF158832 2 310 2.35E-114 T 29-03-2018 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SUPERFAMILY SSF47781 549 627 2.18E-18 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Gene3D G3DSA:1.10.150.310 488 625 4.6E-51 T 29-03-2018 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Pfam PF00575 S1 RNA binding domain 644 715 3.4E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SUPERFAMILY SSF53098 311 458 1.29E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Pfam PF09371 Tex-like protein N-terminal domain 9 193 1.4E-70 T 29-03-2018 IPR018974 Tex-like protein, N-terminal HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SUPERFAMILY SSF50249 630 717 1.79E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Pfam PF16921 Tex protein YqgF-like domain 315 440 1.7E-58 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Gene3D G3DSA:2.40.50.140 636 718 8.3E-28 T 29-03-2018 HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 Gene3D G3DSA:1.10.10.650 1 108 1.1E-32 T 29-03-2018 IPR023319 Tex-like protein, HTH domain HVS_RS01785 a025b4b2801d35006a29476916cf59bb 718 SMART SM00732 315 413 9.3E-36 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 HVS_RS10355 b6a4f85803d49c87c08327de5c9f7e6f 460 Gene3D G3DSA:3.40.1190.10 46 314 3.8E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10355 b6a4f85803d49c87c08327de5c9f7e6f 460 Pfam PF08245 Mur ligase middle domain 54 289 1.1E-20 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10355 b6a4f85803d49c87c08327de5c9f7e6f 460 Pfam PF08353 Domain of unknown function (DUF1727) 328 442 1.2E-36 T 29-03-2018 IPR013564 Domain of unknown function DUF1727 HVS_RS10355 b6a4f85803d49c87c08327de5c9f7e6f 460 SUPERFAMILY SSF53623 41 195 3.66E-38 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10355 b6a4f85803d49c87c08327de5c9f7e6f 460 SUPERFAMILY SSF53623 229 307 3.66E-38 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10355 b6a4f85803d49c87c08327de5c9f7e6f 460 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 52 75 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 SUPERFAMILY SSF53335 3 474 4.86E-123 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 Pfam PF02384 N-6 DNA Methylase 140 442 5.4E-79 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 270 276 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 Pfam PF12161 HsdM N-terminal domain 4 130 8.2E-16 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 Gene3D G3DSA:3.40.50.150 160 436 2.1E-60 T 29-03-2018 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 320 2.4E-20 T 29-03-2018 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 200 2.4E-20 T 29-03-2018 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 162 178 2.4E-20 T 29-03-2018 HVS_RS14910 d14bc58923bee82d58a6791a0d1fbcb2 476 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 267 279 2.4E-20 T 29-03-2018 HVS_RS08565 2639b3e67932dc603ae219a15fd47c43 388 SUPERFAMILY SSF53383 11 386 1.86E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS08565 2639b3e67932dc603ae219a15fd47c43 388 Gene3D G3DSA:3.40.640.10 53 271 3.3E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS08565 2639b3e67932dc603ae219a15fd47c43 388 Gene3D G3DSA:3.90.1150.10 272 388 3.9E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS08565 2639b3e67932dc603ae219a15fd47c43 388 Pfam PF00155 Aminotransferase class I and II 38 378 5.6E-65 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS08565 2639b3e67932dc603ae219a15fd47c43 388 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 HVS_RS08565 2639b3e67932dc603ae219a15fd47c43 388 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 22 379 8.2E-141 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 SMART SM00306 20 114 1.7E-11 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 133 156 2.5E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 SUPERFAMILY SSF51294 22 155 1.13E-28 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 Gene3D G3DSA:2.170.16.10 5 156 1.4E-38 T 29-03-2018 HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 22 92 5.0E-8 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 Pfam PF07591 Pretoxin HINT domain 28 157 1.8E-32 T 29-03-2018 HVS_RS02000 59b04a2f2c07e3548f15b87856b03aff 264 Pfam PF15529 Bacterial toxin 24 172 258 8.2E-21 T 29-03-2018 IPR029114 Bacterial toxin 24 HVS_RS06610 9be5f7af97ef9ef10b9c85b8bac52fa4 264 Pfam PF06114 IrrE N-terminal-like domain 45 169 3.7E-17 T 29-03-2018 IPR010359 IrrE N-terminal-like domain HVS_RS10760 734796b37362dddb22899820502eab26 484 SUPERFAMILY SSF54556 297 362 6.11E-7 T 29-03-2018 IPR029070 Chitinase insertion domain HVS_RS10760 734796b37362dddb22899820502eab26 484 Gene3D G3DSA:1.10.1330.10 417 484 3.2E-4 T 29-03-2018 HVS_RS10760 734796b37362dddb22899820502eab26 484 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 455 474 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS10760 734796b37362dddb22899820502eab26 484 ProSitePatterns PS01095 Chitinases family 18 active site. 156 164 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 HVS_RS10760 734796b37362dddb22899820502eab26 484 Pfam PF00404 Dockerin type I repeat 419 439 1.4E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS10760 734796b37362dddb22899820502eab26 484 Pfam PF00704 Glycosyl hydrolases family 18 34 391 3.2E-97 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HVS_RS10760 734796b37362dddb22899820502eab26 484 SUPERFAMILY SSF51445 29 297 7.53E-104 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS10760 734796b37362dddb22899820502eab26 484 SUPERFAMILY SSF51445 363 394 7.53E-104 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS10760 734796b37362dddb22899820502eab26 484 Gene3D G3DSA:3.20.20.80 25 416 1.7E-103 T 29-03-2018 HVS_RS10760 734796b37362dddb22899820502eab26 484 SUPERFAMILY SSF63446 415 483 4.22E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS10760 734796b37362dddb22899820502eab26 484 SMART SM00636 33 391 2.5E-131 T 29-03-2018 IPR011583 Chitinase II GO:0008061 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 76 564 3.0E-215 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 218 433 2.7E-70 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 70 569 45.017 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 440 563 9.1E-37 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 SUPERFAMILY SSF47917 441 567 2.35E-31 T 29-03-2018 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 424 433 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Gene3D G3DSA:3.40.50.300 152 433 6.7E-112 T 29-03-2018 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 SUPERFAMILY SSF52540 165 439 1.18E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Gene3D G3DSA:2.40.30.20 73 151 9.8E-25 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 SUPERFAMILY SSF50615 80 162 4.71E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Gene3D G3DSA:1.20.150.20 442 568 1.2E-34 T 29-03-2018 HVS_RS03645 b048175711ec592686f2f8a3068e71e8 573 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 95 161 2.8E-12 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Pfam PF13604 AAA domain 319 495 1.4E-44 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Gene3D G3DSA:1.10.150.20 96 128 1.2E-6 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Gene3D G3DSA:1.10.150.20 129 190 3.1E-6 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Gene3D G3DSA:1.10.150.20 39 95 0.034 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Pfam PF13538 UvrD-like helicase C-terminal domain 635 682 1.0E-17 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SMART SM00382 331 443 2.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SMART SM00278 182 201 310.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SMART SM00278 118 137 1.1 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SMART SM00278 90 104 940.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 4 708 1.4E-224 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Gene3D G3DSA:1.10.8.50 191 268 0.0072 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SUPERFAMILY SSF52540 181 475 5.81E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Pfam PF14490 Helix-hairpin-helix containing domain 140 230 7.3E-34 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Gene3D G3DSA:3.40.50.300 276 485 9.3E-39 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 711 28.725 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SUPERFAMILY SSF52540 426 493 6.38E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SUPERFAMILY SSF52540 536 707 6.38E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 Gene3D G3DSA:3.40.50.300 486 695 9.2E-31 T 29-03-2018 HVS_RS04165 2029ae9cc72652144980af7d70d972f5 712 SUPERFAMILY SSF47781 87 158 7.66E-11 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS13410 63f039a4502b471b8fb17ea90475e21b 369 SUPERFAMILY SSF53756 3 304 1.43E-51 T 29-03-2018 HVS_RS13410 63f039a4502b471b8fb17ea90475e21b 369 Pfam PF00534 Glycosyl transferases group 1 185 302 1.5E-26 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS13410 63f039a4502b471b8fb17ea90475e21b 369 Gene3D G3DSA:3.40.50.2000 155 329 1.1E-31 T 29-03-2018 HVS_RS10390 991bf1870d090b8b865c84f8d3bc187a 328 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 312 1.2E-42 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HVS_RS10390 991bf1870d090b8b865c84f8d3bc187a 328 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 12 322 3.8E-41 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 564 9.3E-166 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 SUPERFAMILY SSF52540 1 220 1.7E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 PIRSF PIRSF003128 1 568 2.6E-175 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 523 5.4E-14 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 SUPERFAMILY SSF52540 4 50 2.26E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 SUPERFAMILY SSF52540 311 517 2.26E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 Gene3D G3DSA:3.40.50.300 1 167 1.2E-25 T 29-03-2018 HVS_RS09740 ecfceacfec1521a4759e01d9907e9d25 572 Gene3D G3DSA:3.40.50.300 168 529 2.6E-13 T 29-03-2018 HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 Pfam PF07591 Pretoxin HINT domain 359 488 2.0E-31 T 29-03-2018 HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 Pfam PF05593 RHS Repeat 10 42 5.7E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 353 423 1.2E-7 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 Gene3D G3DSA:2.170.16.10 344 487 1.4E-37 T 29-03-2018 HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 141 220 5.6E-20 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 464 487 7.0E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 SUPERFAMILY SSF51294 353 488 1.14E-27 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02010 9a3a66c4f3ace17cb88ea6e6c2886d02 609 SMART SM00306 351 445 6.8E-13 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 SUPERFAMILY SSF75005 52 344 7.71E-51 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Gene3D G3DSA:2.80.10.50 405 446 1.8E-14 T 29-03-2018 HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 SMART SM00458 354 491 5.2E-11 T 29-03-2018 IPR000772 Ricin B, lectin domain HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Gene3D G3DSA:2.80.10.50 447 541 5.8E-17 T 29-03-2018 HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 SUPERFAMILY SSF50370 354 491 2.6E-45 T 29-03-2018 IPR000772 Ricin B, lectin domain HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 354 431 1.6E-20 T 29-03-2018 IPR000772 Ricin B, lectin domain HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 438 501 7.8E-16 T 29-03-2018 IPR000772 Ricin B, lectin domain HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Pfam PF04616 Glycosyl hydrolases family 43 60 271 4.6E-18 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Gene3D G3DSA:2.115.10.20 25 343 4.5E-62 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 SUPERFAMILY SSF63446 497 562 2.26E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS04160 8f6ca258f2305d1de18c0bc4e5c29b8f 565 Gene3D G3DSA:4.10.1090.10 344 404 5.0E-17 T 29-03-2018 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Gene3D G3DSA:1.25.40.10 233 265 0.19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Pfam PF01535 PPR repeat 96 115 0.43 T 29-03-2018 IPR002885 Pentatricopeptide repeat HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Gene3D G3DSA:1.25.40.10 136 177 1.8E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Pfam PF13181 Tetratricopeptide repeat 224 250 5.0E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Pfam PF13181 Tetratricopeptide repeat 157 185 0.0016 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 SUPERFAMILY SSF81901 58 253 1.02E-25 T 29-03-2018 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Gene3D G3DSA:1.25.40.10 196 232 3.2E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Gene3D G3DSA:1.25.40.10 53 135 1.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Pfam PF13374 Tetratricopeptide repeat 125 152 0.017 T 29-03-2018 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 SMART SM00028 155 188 1.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 SMART SM00028 189 222 0.0014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 SMART SM00028 223 256 210.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Gene3D G3DSA:1.20.5.1140 178 195 0.0036 T 29-03-2018 HVS_RS07250 893053716a733c07866d2b5f9aa0b7c5 280 Pfam PF07719 Tetratricopeptide repeat 190 221 4.2E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 HVS_RS04185 ed88cc4be4cea90cefe800937bf6c81e 345 SUPERFAMILY SSF48225 34 238 5.36E-6 T 29-03-2018 IPR001382 Glycoside hydrolase family 47 GO:0004571|GO:0005509|GO:0016020 KEGG: 00500+3.2.1.11|KEGG: 00510+3.2.1.113|KEGG: 00513+3.2.1.113 HVS_RS04185 ed88cc4be4cea90cefe800937bf6c81e 345 Gene3D G3DSA:1.50.10.10 16 339 2.8E-33 T 29-03-2018 HVS_RS04185 ed88cc4be4cea90cefe800937bf6c81e 345 SUPERFAMILY SSF48208 160 327 2.01E-15 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1185 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 SMART SM00968 525 644 2.5E-37 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 SUPERFAMILY SSF52540 1071 1184 1.07E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 SUPERFAMILY SSF52540 1 210 1.07E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:1.20.5.730 270 351 4.2E-5 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 SUPERFAMILY SSF75553 482 692 1.96E-51 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:1.20.58.60 611 800 8.7E-4 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1179 3.8E-62 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:1.10.287.510 436 522 0.045 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:3.40.50.300 947 1189 3.4E-35 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:3.40.50.300 1 236 6.7E-42 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:1.20.1480.30 352 435 0.12 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Pfam PF06470 SMC proteins Flexible Hinge Domain 525 644 3.7E-29 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Gene3D G3DSA:1.20.5.50 801 946 0.045 T 29-03-2018 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1187 23.504 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HVS_RS08790 3768c780d02473079182c71c50fcd9f4 1190 PIRSF PIRSF005719 1 1190 0.0 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein HVS_RS10040 ed659cb702eb4d858e9211a7e82f9bcd 89 Pfam PF13740 ACT domain 4 77 2.3E-17 T 29-03-2018 HVS_RS10040 ed659cb702eb4d858e9211a7e82f9bcd 89 SUPERFAMILY SSF55021 1 83 2.75E-21 T 29-03-2018 HVS_RS10040 ed659cb702eb4d858e9211a7e82f9bcd 89 Hamap MF_01054 UPF0237 protein . 1 89 28.139 T 29-03-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type HVS_RS10040 ed659cb702eb4d858e9211a7e82f9bcd 89 Gene3D G3DSA:3.30.70.260 1 84 3.4E-21 T 29-03-2018 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Gene3D G3DSA:3.40.50.300 9 414 2.5E-34 T 29-03-2018 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Pfam PF02151 UvrB/uvrC motif 622 656 1.9E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 SUPERFAMILY SSF52540 2 413 1.0E-139 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Pfam PF04851 Type III restriction enzyme, res subunit 15 137 2.8E-10 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 SMART SM00487 8 424 2.2E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 SUPERFAMILY SSF46600 610 656 2.48E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Pfam PF12344 Ultra-violet resistance protein B 550 592 1.9E-23 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 SUPERFAMILY SSF52540 36 81 1.27E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 SUPERFAMILY SSF52540 457 570 1.27E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 SMART SM00490 458 544 5.2E-21 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 657 45.204 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Pfam PF00271 Helicase conserved C-terminal domain 434 542 1.9E-18 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Gene3D G3DSA:3.40.50.300 415 587 4.4E-34 T 29-03-2018 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 Gene3D G3DSA:4.10.860.10 595 658 7.8E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS05250 4734f6c7721d7c586980c7a506daec16 659 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 655 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HVS_RS03220 ef0bd2446caadb0f723451fccd36676a 403 SUPERFAMILY SSF56954 44 398 1.7E-31 T 29-03-2018 HVS_RS03220 ef0bd2446caadb0f723451fccd36676a 403 Pfam PF02321 Outer membrane efflux protein 287 395 4.1E-6 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HVS_RS03220 ef0bd2446caadb0f723451fccd36676a 403 Pfam PF02321 Outer membrane efflux protein 126 221 3.2E-10 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HVS_RS03220 ef0bd2446caadb0f723451fccd36676a 403 Gene3D G3DSA:1.20.1600.10 120 281 6.5E-18 T 29-03-2018 HVS_RS03220 ef0bd2446caadb0f723451fccd36676a 403 Gene3D G3DSA:1.20.1600.10 283 401 3.3E-10 T 29-03-2018 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 6 215 1.9E-72 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 Gene3D G3DSA:3.20.20.70 2 222 1.9E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 3 219 33.227 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 SMART SM01133 4 217 6.1E-90 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 SUPERFAMILY SSF51569 6 217 1.88E-76 T 29-03-2018 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 PIRSF PIRSF001357 1 225 8.9E-74 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HVS_RS14250 93d71e3a0cccf7a16b0d12f19a097831 226 Pfam PF01791 DeoC/LacD family aldolase 4 201 1.6E-20 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 HVS_RS06555 89539b00b43203945c64fa550806916e 687 SUPERFAMILY SSF57783 27 116 1.43E-12 T 29-03-2018 HVS_RS06555 89539b00b43203945c64fa550806916e 687 SUPERFAMILY SSF56731 255 481 6.8E-14 T 29-03-2018 HVS_RS06555 89539b00b43203945c64fa550806916e 687 Gene3D G3DSA:3.40.1360.10 355 483 2.1E-13 T 29-03-2018 HVS_RS06555 89539b00b43203945c64fa550806916e 687 Gene3D G3DSA:3.90.580.10 25 271 1.7E-11 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HVS_RS06555 89539b00b43203945c64fa550806916e 687 SMART SM00400 58 114 3.0E-4 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HVS_RS06555 89539b00b43203945c64fa550806916e 687 Pfam PF01807 CHC2 zinc finger 57 105 5.3E-9 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HVS_RS06555 89539b00b43203945c64fa550806916e 687 Pfam PF08275 DNA primase catalytic core, N-terminal domain 249 332 3.8E-5 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Pfam PF07833 Copper amine oxidase N-terminal domain 543 634 1.7E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Pfam PF07833 Copper amine oxidase N-terminal domain 508 553 6.6E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 SUPERFAMILY SSF54106 100 145 4.97E-8 T 29-03-2018 IPR018392 LysM domain HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 SMART SM00257 101 145 1.4E-9 T 29-03-2018 IPR018392 LysM domain HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Pfam PF00704 Glycosyl hydrolases family 18 179 462 1.8E-20 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Gene3D G3DSA:3.10.350.10 98 133 2.9E-10 T 29-03-2018 HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 SUPERFAMILY SSF55383 545 629 7.45E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Gene3D G3DSA:3.20.20.80 134 485 7.2E-28 T 29-03-2018 HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 SUPERFAMILY SSF51445 150 356 3.33E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 SUPERFAMILY SSF51445 435 478 3.33E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 SUPERFAMILY SSF55383 508 558 2.22E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Pfam PF01476 LysM domain 102 145 9.1E-9 T 29-03-2018 IPR018392 LysM domain HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Gene3D G3DSA:3.30.457.10 615 636 8.2E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Gene3D G3DSA:3.30.457.10 486 554 9.8E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12440 b37092013cc8891af555f01e44ff8ccc 637 Gene3D G3DSA:3.30.457.10 555 614 6.6E-23 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 Gene3D G3DSA:1.20.1560.10 1 325 2.5E-44 T 29-03-2018 HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 SMART SM00382 364 550 6.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 SUPERFAMILY SSF52540 339 553 3.17E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 SUPERFAMILY SSF90123 1 325 1.01E-47 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 Pfam PF00005 ABC transporter 355 505 4.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 Gene3D G3DSA:3.40.50.300 326 577 8.9E-57 T 29-03-2018 HVS_RS06200 a1e15e42fb9791b395aabd0becf7f588 636 Pfam PF00664 ABC transporter transmembrane region 22 291 1.5E-24 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 SUPERFAMILY SSF51294 622 755 1.13E-25 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Gene3D G3DSA:2.120.10.30 45 354 0.004 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Pfam PF05593 RHS Repeat 92 125 1.9E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Pfam PF05593 RHS Repeat 26 62 1.1E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Pfam PF05593 RHS Repeat 243 272 9.7E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Pfam PF05593 RHS Repeat 129 166 8.0E-11 T 29-03-2018 IPR031325 RHS repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Pfam PF05593 RHS Repeat 279 309 2.3E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 279 314 0.0012 T 29-03-2018 IPR006530 YD repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 88 128 8.2E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 129 170 9.4E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 47 87 5.5E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 410 490 1.1E-17 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 733 757 0.0014 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 SMART SM00306 620 714 1.4E-11 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Pfam PF07591 Pretoxin HINT domain 628 757 1.2E-29 T 29-03-2018 HVS_RS04070 14904124076ff4fc6c1b7826ff1eca85 867 Gene3D G3DSA:2.170.16.10 607 756 4.5E-38 T 29-03-2018 HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 Gene3D G3DSA:1.20.200.10 102 472 8.7E-102 T 29-03-2018 HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 SUPERFAMILY SSF48557 8 454 2.36E-98 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 452 2.4E-18 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 Pfam PF00206 Lyase 56 303 1.7E-21 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 Gene3D G3DSA:1.10.275.10 2 101 5.9E-25 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 SMART SM00998 369 453 1.0E-26 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 9.5E-10 T 29-03-2018 IPR000362 Fumarate lyase family HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 9.5E-10 T 29-03-2018 IPR000362 Fumarate lyase family HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 9.5E-10 T 29-03-2018 IPR000362 Fumarate lyase family HVS_RS09170 9be401d6d1a3915d86f580036c712d3e 475 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 9 452 5.3E-121 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 90 284 1.8E-27 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 Gene3D G3DSA:3.30.413.10 21 288 5.4E-38 T 29-03-2018 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 SUPERFAMILY SSF56014 92 159 4.19E-36 T 29-03-2018 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 SUPERFAMILY SSF56014 217 283 4.19E-36 T 29-03-2018 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 Pfam PF12838 4Fe-4S dicluster domain 165 211 2.5E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 137 153 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 PRINTS PR00397 Sirohaem Fe-binding site signature 94 112 3.9E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 PRINTS PR00397 Sirohaem Fe-binding site signature 137 155 3.9E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 166 177 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 19 79 3.1E-18 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 SUPERFAMILY SSF54862 141 213 1.43E-19 T 29-03-2018 HVS_RS02660 fd222f3ee9954007016a7f41aa2bf296 288 SUPERFAMILY SSF55124 4 96 9.16E-22 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 HVS_RS09590 54b8879d1e00e6d03eea919435955d41 172 Gene3D G3DSA:3.30.420.10 1 159 2.1E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS09590 54b8879d1e00e6d03eea919435955d41 172 Pfam PF00075 RNase H 2 149 2.3E-44 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HVS_RS09590 54b8879d1e00e6d03eea919435955d41 172 Hamap MF_00042 Ribonuclease H [rnhA]. 1 157 27.235 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 HVS_RS09590 54b8879d1e00e6d03eea919435955d41 172 SUPERFAMILY SSF53098 4 149 6.2E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS07520 168d8079e6335adec167d39e9326ca35 209 Hamap MF_01114 Regulatory protein RecX [recX]. 41 206 15.261 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 HVS_RS07520 168d8079e6335adec167d39e9326ca35 209 Gene3D G3DSA:1.10.10.10 108 152 1.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07520 168d8079e6335adec167d39e9326ca35 209 Gene3D G3DSA:1.10.10.10 42 106 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07520 168d8079e6335adec167d39e9326ca35 209 Gene3D G3DSA:1.10.10.10 156 203 1.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07520 168d8079e6335adec167d39e9326ca35 209 Pfam PF02631 RecX family 84 204 4.4E-29 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 HVS_RS06100 8e595b184813d82e79504233d82b0a43 557 SUPERFAMILY SSF53850 61 553 4.39E-112 T 29-03-2018 HVS_RS06100 8e595b184813d82e79504233d82b0a43 557 Gene3D G3DSA:3.90.76.10 81 174 1.2E-25 T 29-03-2018 HVS_RS06100 8e595b184813d82e79504233d82b0a43 557 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 466 1.1E-82 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain HVS_RS06100 8e595b184813d82e79504233d82b0a43 557 PIRSF PIRSF002741 25 557 6.3E-109 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HVS_RS06100 8e595b184813d82e79504233d82b0a43 557 Gene3D G3DSA:3.40.190.10 175 315 2.6E-34 T 29-03-2018 HVS_RS06100 8e595b184813d82e79504233d82b0a43 557 Gene3D G3DSA:3.10.105.10 316 522 1.0E-47 T 29-03-2018 HVS_RS14725 8e595b184813d82e79504233d82b0a43 557 SUPERFAMILY SSF53850 61 553 4.39E-112 T 29-03-2018 HVS_RS14725 8e595b184813d82e79504233d82b0a43 557 Gene3D G3DSA:3.90.76.10 81 174 1.2E-25 T 29-03-2018 HVS_RS14725 8e595b184813d82e79504233d82b0a43 557 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 466 1.1E-82 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain HVS_RS14725 8e595b184813d82e79504233d82b0a43 557 PIRSF PIRSF002741 25 557 6.3E-109 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HVS_RS14725 8e595b184813d82e79504233d82b0a43 557 Gene3D G3DSA:3.40.190.10 175 315 2.6E-34 T 29-03-2018 HVS_RS14725 8e595b184813d82e79504233d82b0a43 557 Gene3D G3DSA:3.10.105.10 316 522 1.0E-47 T 29-03-2018 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 SUPERFAMILY SSF52172 1 148 2.85E-38 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 SUPERFAMILY SSF81606 177 379 6.54E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 Gene3D G3DSA:3.40.50.2300 1 137 3.3E-32 T 29-03-2018 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 Gene3D G3DSA:3.60.40.10 138 383 1.8E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 SMART SM00331 164 383 2.4E-19 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 191 383 7.9E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 SMART SM00448 2 115 2.4E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS07105 09e64708849c69b787b8bb6d117275c9 384 Pfam PF00072 Response regulator receiver domain 4 115 2.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS11440 758a31d97e83d1993f9e5f7a90aa7170 175 Gene3D G3DSA:3.40.30.10 87 174 2.9E-20 T 29-03-2018 HVS_RS11440 758a31d97e83d1993f9e5f7a90aa7170 175 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 27 168 1.0E-51 T 29-03-2018 HVS_RS11440 758a31d97e83d1993f9e5f7a90aa7170 175 PIRSF PIRSF000216 4 175 9.6E-60 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11440 758a31d97e83d1993f9e5f7a90aa7170 175 SUPERFAMILY SSF52833 17 172 1.9E-54 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 Pfam PF01256 Carbohydrate kinase 255 508 2.4E-57 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 Pfam PF03853 YjeF-related protein N-terminus 26 195 7.6E-48 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 SUPERFAMILY SSF53613 233 512 5.39E-72 T 29-03-2018 IPR029056 Ribokinase-like HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 3 217 8.6E-49 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 216 25.049 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 233 512 5.9E-66 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 Gene3D G3DSA:3.40.50.10260 1 234 1.2E-68 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 Gene3D G3DSA:3.40.1190.20 235 516 1.6E-45 T 29-03-2018 IPR029056 Ribokinase-like HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 231 516 22.625 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 PIRSF PIRSF017184 1 516 3.3E-149 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 451 461 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site HVS_RS14020 04cbb4f1e69a3f25713b369517d3e7b1 516 SUPERFAMILY SSF64153 2 252 8.11E-63 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 SUPERFAMILY SSF54106 285 333 2.62E-10 T 29-03-2018 IPR018392 LysM domain HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 Gene3D G3DSA:3.10.350.10 281 334 3.7E-18 T 29-03-2018 HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 SMART SM00644 8 169 1.6E-20 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 22 149 3.0E-18 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 SUPERFAMILY SSF55846 2 182 7.85E-41 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 SMART SM00257 287 333 2.1E-12 T 29-03-2018 IPR018392 LysM domain HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 Gene3D G3DSA:3.40.80.10 1 197 1.8E-36 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS13515 08a1ce8b7c17373a9c0fd8815235f211 334 Pfam PF01476 LysM domain 288 333 9.6E-15 T 29-03-2018 IPR018392 LysM domain HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 Pfam PF08708 Primase C terminal 1 (PriCT-1) 207 272 1.9E-17 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 9 182 2.0E-44 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 SMART SM00942 206 272 2.0E-22 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 SUPERFAMILY SSF56747 5 192 3.6E-27 T 29-03-2018 HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 387 687 4.0E-100 T 29-03-2018 IPR006500 DNA primase, phage/plasmid HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 SMART SM00885 287 438 2.0E-53 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 Pfam PF03288 Poxvirus D5 protein-like 644 695 2.2E-4 T 29-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 SUPERFAMILY SSF52540 455 617 9.5E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 Gene3D G3DSA:3.40.50.300 404 623 1.6E-16 T 29-03-2018 HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 Pfam PF08706 D5 N terminal like 287 437 1.2E-35 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS03915 b6e39fe3bb326f0c0a679632fe343535 724 SMART SM00943 9 184 2.9E-65 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS15130 43991c43de1eac8886324857eac63269 117 SUPERFAMILY SSF54189 6 86 1.4E-30 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15130 43991c43de1eac8886324857eac63269 117 Gene3D G3DSA:3.30.70.330 3 109 3.9E-30 T 29-03-2018 HVS_RS15130 43991c43de1eac8886324857eac63269 117 Pfam PF00276 Ribosomal protein L23 6 85 2.3E-31 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HVS_RS15130 43991c43de1eac8886324857eac63269 117 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.593 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 SUPERFAMILY SSF53795 155 316 6.71E-40 T 29-03-2018 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 Gene3D G3DSA:3.40.50.300 153 326 1.4E-46 T 29-03-2018 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 Pfam PF07475 HPr Serine kinase C-terminal domain 151 317 3.7E-73 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 21 325 39.433 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 23 321 4.6E-115 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 Pfam PF02603 HPr Serine kinase N terminus 22 146 3.0E-42 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 Gene3D G3DSA:3.40.1390.20 21 151 3.3E-41 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HVS_RS12115 89058339e6ed06a0a5f8857537ba5fd8 332 SUPERFAMILY SSF75138 25 147 5.62E-32 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HVS_RS08080 84ff7948a95e991639e19cf786907a37 197 Pfam PF01553 Acyltransferase 19 147 3.8E-25 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HVS_RS08080 84ff7948a95e991639e19cf786907a37 197 Gene3D G3DSA:3.40.1130.10 1 197 6.2E-43 T 29-03-2018 HVS_RS08080 84ff7948a95e991639e19cf786907a37 197 SUPERFAMILY SSF69593 11 196 3.27E-50 T 29-03-2018 HVS_RS08080 84ff7948a95e991639e19cf786907a37 197 SMART SM00563 34 150 2.8E-32 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HVS_RS08080 84ff7948a95e991639e19cf786907a37 197 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 20 147 4.5E-31 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 HVS_RS08965 ec87da3228302fbebc694376ae73cac1 341 Gene3D G3DSA:3.40.1780.10 1 133 1.8E-42 T 29-03-2018 HVS_RS08965 ec87da3228302fbebc694376ae73cac1 341 Gene3D G3DSA:3.40.1780.10 173 341 8.4E-70 T 29-03-2018 HVS_RS08965 ec87da3228302fbebc694376ae73cac1 341 Pfam PF02547 Queuosine biosynthesis protein 3 340 2.8E-144 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HVS_RS08965 ec87da3228302fbebc694376ae73cac1 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 46.467 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HVS_RS08965 ec87da3228302fbebc694376ae73cac1 341 SUPERFAMILY SSF111337 1 340 1.12E-140 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HVS_RS08965 ec87da3228302fbebc694376ae73cac1 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 340 2.3E-137 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 HVS_RS10905 1d6a80f0093906a4694461dd094b4bdd 304 TIGRFAM TIGR00277 HDIG: HDIG domain 123 213 1.8E-7 T 29-03-2018 IPR006675 HDIG domain HVS_RS10905 1d6a80f0093906a4694461dd094b4bdd 304 Pfam PF01966 HD domain 125 245 1.3E-22 T 29-03-2018 IPR006674 HD domain HVS_RS10905 1d6a80f0093906a4694461dd094b4bdd 304 SUPERFAMILY SSF109604 98 283 3.38E-43 T 29-03-2018 HVS_RS10905 1d6a80f0093906a4694461dd094b4bdd 304 Gene3D G3DSA:1.10.3210.10 91 295 8.8E-56 T 29-03-2018 HVS_RS10905 1d6a80f0093906a4694461dd094b4bdd 304 SMART SM00471 119 254 1.3E-12 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS11320 06f04a6ccfafce3aa306bfa16e4e2851 96 SUPERFAMILY SSF48295 2 93 4.24E-32 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 HVS_RS11320 06f04a6ccfafce3aa306bfa16e4e2851 96 Pfam PF01371 Trp repressor protein 11 93 4.9E-31 T 29-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 HVS_RS11320 06f04a6ccfafce3aa306bfa16e4e2851 96 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 6 93 3.1E-45 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD HVS_RS11320 06f04a6ccfafce3aa306bfa16e4e2851 96 Gene3D G3DSA:1.10.1270.10 1 96 2.8E-30 T 29-03-2018 HVS_RS11320 06f04a6ccfafce3aa306bfa16e4e2851 96 PIRSF PIRSF012508 1 96 2.9E-48 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SUPERFAMILY SSF55326 299 435 4.53E-30 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SUPERFAMILY SSF55326 207 233 4.53E-30 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SUPERFAMILY SSF55326 638 815 1.78E-42 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.30.1330.10 207 436 1.9E-42 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.30.1280.10 5 65 0.0046 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 6 1254 0.0 T 29-03-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SUPERFAMILY SSF56042 442 662 1.15E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SMART SM01211 991 1254 1.3E-99 T 29-03-2018 HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Pfam PF02769 AIR synthase related protein, C-terminal domain 443 594 2.3E-21 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.40.50.880 990 1255 2.5E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 991 1254 5.9E-83 T 29-03-2018 HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.30.1330.10 623 810 2.6E-26 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SUPERFAMILY SSF52317 989 1254 3.38E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 SUPERFAMILY SSF56042 819 963 1.0E-14 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.30.1280.10 82 148 1.2E-4 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.90.650.10 437 610 9.5E-22 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06950 00a24eb4437589b16445eb18d9ad7139 1255 Gene3D G3DSA:3.90.650.10 811 963 3.6E-9 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS07440 6d7fe6acc8140da9d025e87fcdf6abc7 220 Pfam PF07238 PilZ domain 115 211 9.0E-11 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS07440 6d7fe6acc8140da9d025e87fcdf6abc7 220 SUPERFAMILY SSF141371 112 216 2.16E-8 T 29-03-2018 HVS_RS07440 6d7fe6acc8140da9d025e87fcdf6abc7 220 Gene3D G3DSA:2.40.10.220 108 219 1.1E-15 T 29-03-2018 HVS_RS13315 502d778a10aebe6eb40dc8f9485a396b 519 Pfam PF00665 Integrase core domain 139 269 4.0E-15 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS13315 502d778a10aebe6eb40dc8f9485a396b 519 Gene3D G3DSA:3.30.420.10 133 347 4.9E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13315 502d778a10aebe6eb40dc8f9485a396b 519 Gene3D G3DSA:1.10.10.630 407 497 0.0034 T 29-03-2018 IPR034829 DnaD-like domain HVS_RS13315 502d778a10aebe6eb40dc8f9485a396b 519 SUPERFAMILY SSF88659 15 54 3.55E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS13315 502d778a10aebe6eb40dc8f9485a396b 519 SUPERFAMILY SSF53098 149 313 4.3E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13315 502d778a10aebe6eb40dc8f9485a396b 519 Gene3D G3DSA:1.10.10.60 7 56 6.3E-9 T 29-03-2018 HVS_RS02790 502d778a10aebe6eb40dc8f9485a396b 519 Pfam PF00665 Integrase core domain 139 269 4.0E-15 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS02790 502d778a10aebe6eb40dc8f9485a396b 519 Gene3D G3DSA:3.30.420.10 133 347 4.9E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS02790 502d778a10aebe6eb40dc8f9485a396b 519 Gene3D G3DSA:1.10.10.630 407 497 0.0034 T 29-03-2018 IPR034829 DnaD-like domain HVS_RS02790 502d778a10aebe6eb40dc8f9485a396b 519 SUPERFAMILY SSF88659 15 54 3.55E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS02790 502d778a10aebe6eb40dc8f9485a396b 519 SUPERFAMILY SSF53098 149 313 4.3E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS02790 502d778a10aebe6eb40dc8f9485a396b 519 Gene3D G3DSA:1.10.10.60 7 56 6.3E-9 T 29-03-2018 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 36.537 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 SUPERFAMILY SSF55174 2 208 7.07E-73 T 29-03-2018 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 SMART SM00363 98 160 2.7E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 Gene3D G3DSA:1.10.1050.10 147 208 9.7E-16 T 29-03-2018 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 Gene3D G3DSA:3.10.290.10 104 146 2.7E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 Pfam PF01479 S4 domain 99 145 1.1E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 9.0E-33 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 SMART SM01390 3 97 2.7E-54 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 Gene3D G3DSA:1.10.1050.10 1 103 2.3E-42 T 29-03-2018 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15000 252eac5d79ecc3e0b63bc462a4c816cf 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 6.1E-77 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 SUPERFAMILY SSF51735 13 197 5.4E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 295 6.1E-24 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 SUPERFAMILY SSF52413 307 446 2.22E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 PIRSF PIRSF500136 2 448 1.0E-152 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 PIRSF PIRSF000124 12 446 4.9E-58 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 Gene3D G3DSA:3.40.50.720 4 203 3.0E-39 T 29-03-2018 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 13 185 4.3E-35 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 Gene3D G3DSA:3.40.50.720 229 447 7.9E-61 T 29-03-2018 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 13 409 6.7E-122 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 SMART SM00984 322 435 4.2E-32 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 408 5.1E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 Gene3D G3DSA:1.20.5.170 206 228 1.4E-10 T 29-03-2018 HVS_RS13430 7d0dd193cf8ac14c9c580b4ff0c4e377 448 SUPERFAMILY SSF48179 206 297 6.63E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS03865 77cd91f530401b11689f010f3f744f8d 119 SUPERFAMILY SSF48371 4 112 4.55E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 HVS_RS01480 3a05bf6903b51e56b1a3e66b7a2c122f 297 Gene3D G3DSA:3.40.50.150 59 248 1.9E-17 T 29-03-2018 HVS_RS01480 3a05bf6903b51e56b1a3e66b7a2c122f 297 Gene3D G3DSA:2.20.25.10 249 294 3.0E-7 T 29-03-2018 HVS_RS01480 3a05bf6903b51e56b1a3e66b7a2c122f 297 SUPERFAMILY SSF158997 247 290 9.81E-8 T 29-03-2018 HVS_RS01480 3a05bf6903b51e56b1a3e66b7a2c122f 297 Pfam PF13649 Methyltransferase domain 80 174 2.5E-10 T 29-03-2018 HVS_RS01480 3a05bf6903b51e56b1a3e66b7a2c122f 297 SUPERFAMILY SSF53335 37 223 1.91E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 SUPERFAMILY SSF51161 245 419 3.77E-33 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:3.90.550.10 1 236 6.1E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:3.40.120.10 637 722 0.0062 T 29-03-2018 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 248 281 5.2E-6 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:3.40.120.10 380 541 7.1E-20 T 29-03-2018 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:2.160.10.10 311 379 2.1E-10 T 29-03-2018 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 SUPERFAMILY SSF53738 625 725 4.32E-8 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 383 513 1.7E-20 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:2.160.10.10 237 310 4.0E-13 T 29-03-2018 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Pfam PF00483 Nucleotidyl transferase 2 233 9.3E-52 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:3.30.310.50 723 817 2.4E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 SUPERFAMILY SSF53448 1 235 4.55E-79 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 SUPERFAMILY SSF53448 333 349 4.55E-79 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 SUPERFAMILY SSF55957 727 814 9.94E-17 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 SUPERFAMILY SSF53738 375 517 3.92E-23 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS01780 32cc02c6f66e4dd4fb321f90a9647943 817 Gene3D G3DSA:3.40.120.10 542 636 0.0019 T 29-03-2018 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 SUPERFAMILY SSF50465 304 399 5.18E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 SUPERFAMILY SSF52540 9 231 4.4E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Gene3D G3DSA:3.40.50.300 1 74 1.9E-12 T 29-03-2018 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Pfam PF03143 Elongation factor Tu C-terminal domain 304 398 9.6E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 399 8.4E-226 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 400 60.47 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 6.0E-17 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Pfam PF00009 Elongation factor Tu GTP binding domain 10 206 2.4E-60 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 PRINTS PR00315 GTP-binding elongation factor signature 78 88 6.8E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 PRINTS PR00315 GTP-binding elongation factor signature 94 105 6.8E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 PRINTS PR00315 GTP-binding elongation factor signature 131 140 6.8E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.8E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.8E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 SUPERFAMILY SSF50447 210 307 2.36E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Gene3D G3DSA:2.40.30.10 195 304 5.7E-30 T 29-03-2018 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Pfam PF03144 Elongation factor Tu domain 2 230 299 3.9E-19 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Gene3D G3DSA:3.40.50.300 75 194 1.6E-31 T 29-03-2018 HVS_RS12925 59dc0bdf01fc35710e72b10b15fbd2d8 400 Gene3D G3DSA:2.40.30.10 306 399 7.0E-32 T 29-03-2018 HVS_RS05050 0016ba7e3ba44c34f8afb56beb9d434a 333 SUPERFAMILY SSF53901 56 284 3.49E-17 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS05050 0016ba7e3ba44c34f8afb56beb9d434a 333 Gene3D G3DSA:3.40.47.10 33 171 9.1E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS05050 0016ba7e3ba44c34f8afb56beb9d434a 333 PIRSF PIRSF011570 1 333 2.3E-161 T 29-03-2018 IPR010894 Stage V sporulation AD HVS_RS05050 0016ba7e3ba44c34f8afb56beb9d434a 333 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 9.6E-158 T 29-03-2018 IPR010894 Stage V sporulation AD HVS_RS05050 0016ba7e3ba44c34f8afb56beb9d434a 333 Gene3D G3DSA:3.40.50.1100 172 319 7.4E-4 T 29-03-2018 HVS_RS05050 0016ba7e3ba44c34f8afb56beb9d434a 333 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 1.2E-154 T 29-03-2018 IPR010894 Stage V sporulation AD HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 SMART SM00327 405 582 3.4E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 SMART SM00327 65 221 1.5E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 Pfam PF13519 von Willebrand factor type A domain 68 163 2.8E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 Pfam PF07090 Putative glutamine amidotransferase 597 679 2.2E-11 T 29-03-2018 IPR010768 Putative glutamine amidotransferase HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 Gene3D G3DSA:2.60.40.10 682 777 0.0029 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 Gene3D G3DSA:3.40.50.410 59 280 6.6E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 Gene3D G3DSA:3.40.50.880 281 681 5.5E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 Pfam PF00092 von Willebrand factor type A domain 409 575 2.6E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 SUPERFAMILY SSF53300 407 579 1.81E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 SUPERFAMILY SSF52317 274 401 1.3E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 SUPERFAMILY SSF52317 587 680 1.3E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS09120 b3d8770532a19db95ef00899f4c5d27a 933 SUPERFAMILY SSF53300 68 195 6.08E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 34 767 1.7E-172 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 Gene3D G3DSA:3.40.50.300 248 472 1.2E-22 T 29-03-2018 HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 SMART SM00487 285 493 2.3E-22 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 Pfam PF04851 Type III restriction enzyme, res subunit 288 463 1.7E-34 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 30 219 2.0E-47 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 771 1029 1.5E-71 T 29-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal HVS_RS15865 5a2c253374a0a4ebacb2fde7e3340c2c 1033 SUPERFAMILY SSF52540 245 469 1.82E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 SUPERFAMILY SSF102114 136 402 2.62E-62 T 29-03-2018 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 34 466 4.5E-155 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 Pfam PF00919 Uncharacterized protein family UPF0004 34 135 6.8E-29 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 34 469 6.6E-169 T 29-03-2018 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 33 470 72.103 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 SMART SM00729 178 396 5.8E-63 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 182 202 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 Gene3D G3DSA:3.80.30.20 175 410 3.5E-57 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 Pfam PF04055 Radical SAM superfamily 182 352 2.3E-31 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS08440 80df18b067d078812c34f02b73fed12d 472 Pfam PF01938 TRAM domain 410 469 3.9E-10 T 29-03-2018 IPR002792 TRAM domain HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 Gene3D G3DSA:3.40.50.980 207 358 4.3E-36 T 29-03-2018 HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 Gene3D G3DSA:2.30.38.10 359 445 1.3E-24 T 29-03-2018 HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 29-03-2018 IPR020845 AMP-binding, conserved site HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 SUPERFAMILY SSF56801 5 549 4.45E-150 T 29-03-2018 HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 Pfam PF00501 AMP-binding enzyme 37 452 1.5E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 461 539 4.4E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 Gene3D G3DSA:3.30.300.30 448 551 3.5E-29 T 29-03-2018 HVS_RS04890 06ac352c5f844e851f8bf04d1b529038 551 Gene3D G3DSA:3.40.50.980 29 206 3.5E-32 T 29-03-2018 HVS_RS13650 bb4f65cbb1a1754b1b0bcd02faf20d3e 270 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 146 260 1.8E-14 T 29-03-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal HVS_RS01445 854bb15d1be855b645ca67669a574a4f 231 SUPERFAMILY SSF53328 23 157 1.31E-26 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS01445 854bb15d1be855b645ca67669a574a4f 231 Gene3D G3DSA:3.40.50.170 6 220 1.4E-31 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS01445 854bb15d1be855b645ca67669a574a4f 231 SUPERFAMILY SSF50486 165 224 8.63E-21 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 HVS_RS01445 854bb15d1be855b645ca67669a574a4f 231 Pfam PF00551 Formyl transferase 39 121 9.7E-7 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 3 185 41.334 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 Gene3D G3DSA:1.10.286.10 5 53 3.6E-23 T 29-03-2018 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 Pfam PF01227 GTP cyclohydrolase I 8 184 2.2E-77 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 Gene3D G3DSA:3.30.1130.10 54 186 5.6E-57 T 29-03-2018 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 63 79 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 8 184 1.5E-70 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 112 122 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS06075 08f4d906915a4c2f14ca7bddbf399ea6 187 SUPERFAMILY SSF55620 3 185 1.63E-75 T 29-03-2018 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 3 185 41.334 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 Gene3D G3DSA:1.10.286.10 5 53 3.6E-23 T 29-03-2018 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 Pfam PF01227 GTP cyclohydrolase I 8 184 2.2E-77 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 Gene3D G3DSA:3.30.1130.10 54 186 5.6E-57 T 29-03-2018 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 63 79 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 8 184 1.5E-70 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 112 122 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 HVS_RS14750 08f4d906915a4c2f14ca7bddbf399ea6 187 SUPERFAMILY SSF55620 3 185 1.63E-75 T 29-03-2018 HVS_RS03365 6499bb5d1e383cd295e4ffd18f5c82e5 321 SUPERFAMILY SSF56112 19 306 2.04E-26 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS03365 6499bb5d1e383cd295e4ffd18f5c82e5 321 Pfam PF02958 Ecdysteroid kinase 45 144 5.5E-7 T 29-03-2018 IPR004119 Protein of unknown function DUF227 HVS_RS03365 6499bb5d1e383cd295e4ffd18f5c82e5 321 Pfam PF02958 Ecdysteroid kinase 167 266 1.7E-9 T 29-03-2018 IPR004119 Protein of unknown function DUF227 HVS_RS03365 6499bb5d1e383cd295e4ffd18f5c82e5 321 Gene3D G3DSA:3.90.1200.10 123 308 3.6E-16 T 29-03-2018 HVS_RS03365 6499bb5d1e383cd295e4ffd18f5c82e5 321 SMART SM00587 109 266 6.5E-5 T 29-03-2018 IPR015897 CHK kinase-like HVS_RS01465 201bfe22636ec67605519dc852415d58 250 Gene3D G3DSA:3.40.50.720 8 250 1.9E-55 T 29-03-2018 HVS_RS01465 201bfe22636ec67605519dc852415d58 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 247 7.7E-52 T 29-03-2018 HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 SUPERFAMILY SSF51735 11 249 4.74E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS01465 201bfe22636ec67605519dc852415d58 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS01465 201bfe22636ec67605519dc852415d58 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS11680 d4b279567043b05c76e676f13c8ad580 328 PIRSF PIRSF002849 1 319 3.8E-127 T 29-03-2018 HVS_RS11680 d4b279567043b05c76e676f13c8ad580 328 SUPERFAMILY SSF52540 30 290 2.46E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11680 d4b279567043b05c76e676f13c8ad580 328 Gene3D G3DSA:3.40.50.300 1 220 1.5E-23 T 29-03-2018 HVS_RS11680 d4b279567043b05c76e676f13c8ad580 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 3.4E-62 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS11680 d4b279567043b05c76e676f13c8ad580 328 Gene3D G3DSA:1.10.8.300 221 314 1.6E-32 T 29-03-2018 HVS_RS12435 8dd3af3dd42a87882b95914d4b0a6ebf 611 Gene3D G3DSA:1.50.10.10 34 511 2.2E-127 T 29-03-2018 HVS_RS12435 8dd3af3dd42a87882b95914d4b0a6ebf 611 SUPERFAMILY SSF48208 98 520 3.78E-123 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS12435 8dd3af3dd42a87882b95914d4b0a6ebf 611 SUPERFAMILY SSF48208 32 71 3.78E-123 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS12435 8dd3af3dd42a87882b95914d4b0a6ebf 611 Pfam PF00759 Glycosyl hydrolase family 9 35 503 1.7E-117 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12435 8dd3af3dd42a87882b95914d4b0a6ebf 611 Gene3D G3DSA:1.10.1330.10 540 610 2.6E-4 T 29-03-2018 HVS_RS12435 8dd3af3dd42a87882b95914d4b0a6ebf 611 SUPERFAMILY SSF63446 539 608 7.65E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09665 38d5cfa7f9cf3e442ca6bd94640685a4 134 SMART SM00448 1 124 2.6E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09665 38d5cfa7f9cf3e442ca6bd94640685a4 134 SUPERFAMILY SSF52172 1 127 3.7E-25 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS09665 38d5cfa7f9cf3e442ca6bd94640685a4 134 Gene3D G3DSA:3.40.50.2300 1 133 2.1E-25 T 29-03-2018 HVS_RS09665 38d5cfa7f9cf3e442ca6bd94640685a4 134 Pfam PF00072 Response regulator receiver domain 3 123 1.3E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 Gene3D G3DSA:3.40.50.1470 1 190 4.3E-73 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 SUPERFAMILY SSF53178 5 188 3.53E-67 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 181 34.605 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 110 120 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 Pfam PF01195 Peptidyl-tRNA hydrolase 6 188 5.5E-60 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HVS_RS00535 85088395915347c8d26a4dfafa525b6b 190 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 189 7.8E-65 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HVS_RS01120 665a594982e486c63c0bb18741a78543 262 Pfam PF00395 S-layer homology domain 127 169 1.3E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01120 665a594982e486c63c0bb18741a78543 262 Pfam PF00395 S-layer homology domain 88 108 1.4E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01120 665a594982e486c63c0bb18741a78543 262 Pfam PF00395 S-layer homology domain 188 228 4.3E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 20 516 3.8E-178 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 Gene3D G3DSA:3.90.700.10 254 342 1.4E-36 T 29-03-2018 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 PIRSF PIRSF000171 10 532 4.2E-44 T 29-03-2018 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 Pfam PF00890 FAD binding domain 21 392 1.8E-95 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 Gene3D G3DSA:1.20.58.100 424 532 2.6E-25 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 SUPERFAMILY SSF56425 238 352 1.94E-43 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 528 7.3E-18 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 SUPERFAMILY SSF51905 11 255 5.77E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 SUPERFAMILY SSF51905 356 422 5.77E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 Gene3D G3DSA:3.50.50.60 5 253 1.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 22 41 1.2E-6 T 29-03-2018 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.2E-6 T 29-03-2018 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 Gene3D G3DSA:3.50.50.60 343 408 8.3E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS16010 2b771c14d8df78190892fe394190fb14 532 SUPERFAMILY SSF46977 433 529 1.06E-30 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS11220 ae10fd5ec2a8884342be4fb066f98313 247 Gene3D G3DSA:3.40.50.7700 110 247 1.8E-35 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS11220 ae10fd5ec2a8884342be4fb066f98313 247 SMART SM01001 119 247 7.0E-30 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS11220 ae10fd5ec2a8884342be4fb066f98313 247 SUPERFAMILY SSF52255 120 246 1.96E-27 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS11220 ae10fd5ec2a8884342be4fb066f98313 247 Pfam PF00731 AIR carboxylase 121 245 6.5E-14 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 PIRSF PIRSF000478 1 433 4.4E-167 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 SUPERFAMILY SSF52418 69 328 9.94E-93 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 7.4E-24 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 304 3.7E-39 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 Gene3D G3DSA:1.20.970.10 1 66 3.4E-27 T 29-03-2018 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 SUPERFAMILY SSF47648 1 68 2.22E-22 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 344 415 4.9E-23 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 Gene3D G3DSA:3.90.1170.30 337 423 3.2E-25 T 29-03-2018 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 415 8.4E-177 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 Gene3D G3DSA:3.40.1030.10 68 336 5.9E-93 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 SMART SM00941 344 418 6.8E-27 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS09510 f658b7de588d072fb51a9cb6d0d7ec2c 433 SUPERFAMILY SSF54680 331 432 1.29E-23 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS14545 ee49b717e276d5c3cdc0e09d83bace00 162 Pfam PF00692 dUTPase 14 100 6.9E-18 T 29-03-2018 IPR029054 dUTPase-like HVS_RS14545 ee49b717e276d5c3cdc0e09d83bace00 162 Pfam PF00692 dUTPase 117 161 1.1E-4 T 29-03-2018 IPR029054 dUTPase-like HVS_RS14545 ee49b717e276d5c3cdc0e09d83bace00 162 Gene3D G3DSA:2.70.40.10 1 162 8.8E-59 T 29-03-2018 HVS_RS14545 ee49b717e276d5c3cdc0e09d83bace00 162 TIGRFAM TIGR00576 dut: dUTP diphosphatase 12 161 1.8E-38 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 HVS_RS14545 ee49b717e276d5c3cdc0e09d83bace00 162 SUPERFAMILY SSF51283 4 162 2.36E-41 T 29-03-2018 IPR029054 dUTPase-like HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SMART SM01096 420 540 6.7E-44 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:3.30.1490.20 648 737 1.4E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 831 838 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SUPERFAMILY SSF52440 550 668 3.6E-51 T 29-03-2018 IPR016185 Pre-ATP-grasp domain HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SUPERFAMILY SSF52335 933 1069 4.58E-35 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:3.40.50.1380 930 1072 6.5E-37 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Pfam PF02142 MGS-like domain 952 1037 2.7E-19 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:3.30.470.20 738 929 1.6E-31 T 29-03-2018 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SUPERFAMILY SSF56059 128 398 5.13E-94 T 29-03-2018 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:3.30.470.20 120 400 1.7E-55 T 29-03-2018 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SMART SM00851 951 1037 1.3E-29 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SUPERFAMILY SSF52440 1 127 2.59E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:3.40.50.20 538 647 7.5E-53 T 29-03-2018 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SUPERFAMILY SSF56059 666 929 2.12E-94 T 29-03-2018 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 SUPERFAMILY SSF48108 393 545 7.85E-38 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:1.10.1030.10 407 537 1.5E-33 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 860 3.1E-37 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 7.0E-57 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 377 395 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.3E-59 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Gene3D G3DSA:3.40.50.20 4 117 2.6E-35 T 29-03-2018 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1045 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 1.4E-26 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS02455 d51129231fafdde8929b85eef43533b3 1073 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1058 11.997 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS16020 85bd180af26ecc8b9b9c2d4aa4afa7cc 214 Pfam PF04647 Accessory gene regulator B 10 188 1.3E-42 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 HVS_RS16020 85bd180af26ecc8b9b9c2d4aa4afa7cc 214 SMART SM00793 6 198 6.1E-11 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 HVS_RS07970 b762e5e11f6fee8286dc40de125c4054 64 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS07970 b762e5e11f6fee8286dc40de125c4054 64 Pfam PF14697 4Fe-4S dicluster domain 6 57 1.5E-11 T 29-03-2018 HVS_RS07970 b762e5e11f6fee8286dc40de125c4054 64 Gene3D G3DSA:3.30.70.20 2 31 1.3E-6 T 29-03-2018 HVS_RS07970 b762e5e11f6fee8286dc40de125c4054 64 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS07970 b762e5e11f6fee8286dc40de125c4054 64 SUPERFAMILY SSF54862 4 62 3.28E-19 T 29-03-2018 HVS_RS07970 b762e5e11f6fee8286dc40de125c4054 64 Gene3D G3DSA:3.30.70.20 32 64 1.7E-7 T 29-03-2018 HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.0E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 SUPERFAMILY SSF55594 3 87 3.01E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 4.8E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 4.8E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 4.8E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.2E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12910 9263d63f0851de91b84cc5c55f6bc6ac 89 Gene3D G3DSA:3.30.1340.10 1 87 1.8E-25 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SUPERFAMILY SSF47384 365 448 1.04E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SMART SM00304 209 261 1.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 Pfam PF00512 His Kinase A (phospho-acceptor) domain 380 446 1.4E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SUPERFAMILY SSF55785 254 372 1.74E-7 T 29-03-2018 IPR000014 PAS domain HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 494 603 1.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SUPERFAMILY SSF158472 210 258 4.97E-11 T 29-03-2018 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 Gene3D G3DSA:1.10.287.130 386 441 3.9E-21 T 29-03-2018 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 Gene3D G3DSA:3.30.450.20 265 385 2.8E-15 T 29-03-2018 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SMART SM00387 493 605 4.3E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 558 5.7E-22 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 544 5.7E-22 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 602 5.7E-22 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 583 5.7E-22 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SUPERFAMILY SSF55874 437 603 6.68E-51 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 SMART SM00388 380 447 7.3E-25 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 Gene3D G3DSA:3.30.565.10 442 605 1.7E-49 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15965 12ec00ab544631a7308189fc01eefeb9 607 Pfam PF00672 HAMP domain 210 257 2.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Gene3D G3DSA:2.60.40.10 58 161 0.087 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 363 403 1.4E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 510 547 1.7E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 489 524 2.3E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 383 418 1.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 456 488 8.1E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 594 629 2.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 552 591 6.9E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 SUPERFAMILY SSF69304 426 626 1.44E-6 T 29-03-2018 HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Gene3D G3DSA:2.130.10.10 271 648 5.6E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 594 625 1.1E-4 T 29-03-2018 IPR031325 RHS repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 552 589 1.2E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 468 505 3.8E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 489 518 4.2E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS06040 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 510 545 4.2E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Gene3D G3DSA:2.60.40.10 58 161 0.087 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 363 403 1.4E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 510 547 1.7E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 489 524 2.3E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 383 418 1.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 456 488 8.1E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 594 629 2.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 552 591 6.9E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 SUPERFAMILY SSF69304 426 626 1.44E-6 T 29-03-2018 HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Gene3D G3DSA:2.130.10.10 271 648 5.6E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 594 625 1.1E-4 T 29-03-2018 IPR031325 RHS repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 552 589 1.2E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 468 505 3.8E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 489 518 4.2E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS14785 5f783d2a80efcc983fb3f36d42e25179 657 Pfam PF05593 RHS Repeat 510 545 4.2E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS03920 94097eacb9ca11b0e8184b3f470a04f5 437 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 11 421 7.3E-55 T 29-03-2018 IPR024455 Phage capsid HVS_RS03920 94097eacb9ca11b0e8184b3f470a04f5 437 Gene3D G3DSA:3.30.2400.10 163 314 5.5E-20 T 29-03-2018 HVS_RS03920 94097eacb9ca11b0e8184b3f470a04f5 437 Pfam PF05065 Phage capsid family 142 417 1.3E-39 T 29-03-2018 IPR024455 Phage capsid HVS_RS03920 94097eacb9ca11b0e8184b3f470a04f5 437 SUPERFAMILY SSF56563 142 418 1.05E-40 T 29-03-2018 HVS_RS01540 232a5102ce959da6be2fdbb5ef62eaa4 342 PIRSF PIRSF015268 1 337 5.6E-142 T 29-03-2018 IPR011204 Virulence protein RhuM-like HVS_RS01540 232a5102ce959da6be2fdbb5ef62eaa4 342 Pfam PF13310 Virulence protein RhuM family 65 310 2.2E-112 T 29-03-2018 IPR011204 Virulence protein RhuM-like HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 5.0E-29 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Gene3D G3DSA:2.30.30.30 2 60 2.3E-26 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 SUPERFAMILY SSF50104 1 62 4.57E-21 T 29-03-2018 IPR008991 Translation protein SH3-like domain HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 SMART SM00841 129 184 5.4E-35 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.3E-27 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 SUPERFAMILY SSF50249 65 129 2.23E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Gene3D G3DSA:2.40.50.140 129 184 9.2E-30 T 29-03-2018 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 PIRSF PIRSF005901 1 185 1.4E-68 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 SMART SM01185 67 121 2.6E-25 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 7.9E-79 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 52.23 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 SUPERFAMILY SSF50249 128 185 3.17E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Gene3D G3DSA:2.40.50.140 64 127 1.5E-26 T 29-03-2018 HVS_RS08690 655f2b99fe0879f95c13e058081d4d47 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 3.7E-22 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 HVS_RS13895 46cfd14029c58c92d0ab17ad919109ed 339 Gene3D G3DSA:3.40.50.2300 169 306 1.7E-6 T 29-03-2018 HVS_RS13895 46cfd14029c58c92d0ab17ad919109ed 339 Pfam PF04392 ABC transporter substrate binding protein 50 337 9.9E-39 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein HVS_RS13895 46cfd14029c58c92d0ab17ad919109ed 339 SUPERFAMILY SSF53822 40 207 7.07E-10 T 29-03-2018 IPR028082 Periplasmic binding protein-like I HVS_RS13895 46cfd14029c58c92d0ab17ad919109ed 339 Gene3D G3DSA:3.40.50.2300 37 168 2.4E-18 T 29-03-2018 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 PIRSF PIRSF026579 1 184 5.0E-85 T 29-03-2018 IPR014213 Sporulation stage V, protein T HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 183 3.6E-84 T 29-03-2018 IPR014213 Sporulation stage V, protein T HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.7E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 SMART SM00966 8 52 2.1E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-14 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 SUPERFAMILY SSF89447 2 52 6.02E-14 T 29-03-2018 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 Gene3D G3DSA:2.10.260.10 1 40 1.0E-18 T 29-03-2018 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 183 6.3E-49 T 29-03-2018 HVS_RS00550 8aad46c12579e7acf108498daaa01a02 184 Gene3D G3DSA:3.30.450.40 41 184 3.4E-4 T 29-03-2018 IPR029016 GAF domain-like HVS_RS09600 ef3055dbbdead6b54d7e5cbc180b509e 696 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 121 689 1.0E-189 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 HVS_RS09600 ef3055dbbdead6b54d7e5cbc180b509e 696 SUPERFAMILY SSF51998 122 673 1.65E-165 T 29-03-2018 HVS_RS09600 ef3055dbbdead6b54d7e5cbc180b509e 696 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 120 688 1.9E-168 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 HVS_RS09600 ef3055dbbdead6b54d7e5cbc180b509e 696 Gene3D G3DSA:3.20.70.20 126 673 3.2E-193 T 29-03-2018 HVS_RS09600 ef3055dbbdead6b54d7e5cbc180b509e 696 Pfam PF03477 ATP cone domain 4 92 4.9E-22 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 Gene3D G3DSA:1.10.10.60 152 216 6.5E-8 T 29-03-2018 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 SMART SM00342 173 256 1.3E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 Gene3D G3DSA:2.60.120.280 3 146 5.7E-5 T 29-03-2018 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 SUPERFAMILY SSF46689 159 204 7.35E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 Pfam PF12833 Helix-turn-helix domain 179 257 5.7E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 SUPERFAMILY SSF46689 210 258 5.82E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 240 1.4E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 256 1.4E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS09100 f757e756dc29f04363cbeb971ec865a8 259 Gene3D G3DSA:1.10.10.60 217 259 1.7E-15 T 29-03-2018 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 3.0E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 Pfam PF13377 Periplasmic binding protein-like domain 189 349 1.3E-36 T 29-03-2018 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 2.1E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 2 12 2.1E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 Gene3D G3DSA:3.40.50.2300 195 354 4.9E-46 T 29-03-2018 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 Gene3D G3DSA:1.10.260.40 1 53 1.1E-22 T 29-03-2018 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 SUPERFAMILY SSF47413 2 58 5.81E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 SUPERFAMILY SSF53822 87 350 2.17E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 SMART SM00354 1 70 1.7E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 HVS_RS09030 80b2f73e1db6c955ca5ccc00819a3ffe 355 Gene3D G3DSA:3.40.50.2300 54 194 2.8E-19 T 29-03-2018 HVS_RS02785 571c30fd7a5f564a299c73bf97527f98 252 Pfam PF01695 IstB-like ATP binding protein 52 227 9.3E-54 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS02785 571c30fd7a5f564a299c73bf97527f98 252 PIRSF PIRSF003073 1 251 2.2E-61 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS02785 571c30fd7a5f564a299c73bf97527f98 252 Gene3D G3DSA:3.40.50.300 42 228 4.2E-13 T 29-03-2018 HVS_RS02785 571c30fd7a5f564a299c73bf97527f98 252 Pfam PF08483 IstB-like ATP binding N-terminal 25 49 1.8E-8 T 29-03-2018 IPR013690 IstB-like ATP binding N-terminal HVS_RS02785 571c30fd7a5f564a299c73bf97527f98 252 SUPERFAMILY SSF52540 69 225 3.98E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13310 571c30fd7a5f564a299c73bf97527f98 252 Pfam PF01695 IstB-like ATP binding protein 52 227 9.3E-54 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS13310 571c30fd7a5f564a299c73bf97527f98 252 PIRSF PIRSF003073 1 251 2.2E-61 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS13310 571c30fd7a5f564a299c73bf97527f98 252 Gene3D G3DSA:3.40.50.300 42 228 4.2E-13 T 29-03-2018 HVS_RS13310 571c30fd7a5f564a299c73bf97527f98 252 Pfam PF08483 IstB-like ATP binding N-terminal 25 49 1.8E-8 T 29-03-2018 IPR013690 IstB-like ATP binding N-terminal HVS_RS13310 571c30fd7a5f564a299c73bf97527f98 252 SUPERFAMILY SSF52540 69 225 3.98E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09875 3e728f24a8620db9915900bdeceb942e 147 SUPERFAMILY SSF52540 1 138 1.24E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09875 3e728f24a8620db9915900bdeceb942e 147 Gene3D G3DSA:3.40.50.300 1 140 2.9E-27 T 29-03-2018 HVS_RS09875 3e728f24a8620db9915900bdeceb942e 147 Pfam PF00005 ABC transporter 19 138 2.5E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 Gene3D G3DSA:2.30.30.30 119 195 2.0E-34 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 SUPERFAMILY SSF50249 2 124 4.46E-53 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 SMART SM01382 124 253 1.6E-93 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 1.2E-57 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 Gene3D G3DSA:2.40.50.140 1 114 5.9E-51 T 29-03-2018 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.2E-137 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.907 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.3E-33 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 PIRSF PIRSF002158 3 277 1.1E-99 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 SMART SM01383 42 118 2.4E-47 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 SUPERFAMILY SSF50104 126 273 2.17E-62 T 29-03-2018 IPR008991 Translation protein SH3-like domain HVS_RS15125 dcc58d3131e675c1a8215a9ee3081b0a 277 Gene3D G3DSA:4.10.950.10 197 275 6.4E-37 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 Gene3D G3DSA:3.40.50.300 684 993 3.1E-15 T 29-03-2018 HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 Gene3D G3DSA:3.40.50.300 1008 1244 0.017 T 29-03-2018 HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 Gene3D G3DSA:3.40.50.300 310 663 5.5E-26 T 29-03-2018 HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 4 1281 0.0 T 29-03-2018 IPR023839 Firmicutes EssC, C-terminal HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 SMART SM00382 807 972 0.05 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 SMART SM00382 462 634 1.3 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 SUPERFAMILY SSF52540 752 987 1.72E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 SUPERFAMILY SSF52540 425 682 1.73E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 Pfam PF01580 FtsK/SpoIIIE family 794 968 1.4E-27 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HVS_RS05640 f23edc63ca5ca1f1390b0be88d241e0d 1286 Pfam PF01580 FtsK/SpoIIIE family 458 561 2.8E-21 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 PIRSF PIRSF036758 1 409 1.2E-140 T 29-03-2018 IPR015840 DNA methyase, ParB domain-containing HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 Pfam PF01555 DNA methylase 193 388 7.7E-19 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 Pfam PF02195 ParB-like nuclease domain 5 92 2.1E-13 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 Gene3D G3DSA:3.90.1530.10 1 94 2.4E-16 T 29-03-2018 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 SUPERFAMILY SSF53335 159 400 1.35E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 SUPERFAMILY SSF110849 1 99 2.79E-18 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 SMART SM00470 4 93 5.3E-13 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 349 367 1.5E-12 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 330 347 1.5E-12 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 190 204 1.5E-12 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 372 392 1.5E-12 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 Gene3D G3DSA:3.40.50.150 168 404 3.1E-34 T 29-03-2018 HVS_RS13240 403fee2b547ef3711fb32525ae50ee39 417 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 498 554 7.9E-14 T 29-03-2018 HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 SUPERFAMILY SSF63446 29 95 1.47E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 Gene3D G3DSA:2.60.40.10 497 560 3.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 65 84 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 128 363 5.9E-66 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 366 492 2.6E-19 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 ProSitePatterns PS00018 EF-hand calcium-binding domain. 65 77 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS12080 73457b4330271c21d05f13fc24a6989c 1061 Pfam PF08757 CotH kinase protein 624 988 2.6E-68 T 29-03-2018 IPR014867 Spore coat protein CotH HVS_RS12100 4857757bd12d3ad306747d576f3a0940 285 Pfam PF03668 P-loop ATPase protein family 1 284 1.7E-101 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 HVS_RS12100 4857757bd12d3ad306747d576f3a0940 285 PIRSF PIRSF005052 1 285 1.6E-105 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 HVS_RS12100 4857757bd12d3ad306747d576f3a0940 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 40.39 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 HVS_RS12100 4857757bd12d3ad306747d576f3a0940 285 SUPERFAMILY SSF52540 1 156 1.98E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12100 4857757bd12d3ad306747d576f3a0940 285 Gene3D G3DSA:3.40.50.300 1 156 2.7E-13 T 29-03-2018 HVS_RS07185 c70367687c37648be12da7df07d72543 335 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 334 1.3E-60 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 HVS_RS07185 c70367687c37648be12da7df07d72543 335 Gene3D G3DSA:1.10.8.60 144 224 6.3E-19 T 29-03-2018 HVS_RS07185 c70367687c37648be12da7df07d72543 335 SUPERFAMILY SSF52540 11 209 4.57E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07185 c70367687c37648be12da7df07d72543 335 Pfam PF06144 DNA polymerase III, delta subunit 19 190 1.9E-36 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 HVS_RS07185 c70367687c37648be12da7df07d72543 335 SUPERFAMILY SSF48019 216 334 1.96E-20 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HVS_RS07185 c70367687c37648be12da7df07d72543 335 Gene3D G3DSA:1.20.272.10 225 335 8.1E-26 T 29-03-2018 HVS_RS07185 c70367687c37648be12da7df07d72543 335 Gene3D G3DSA:3.40.50.300 1 141 3.0E-28 T 29-03-2018 HVS_RS02355 f91b740dc7fc95cbe61fa409628a0ed0 256 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 9 254 36.092 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS02355 f91b740dc7fc95cbe61fa409628a0ed0 256 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 251 3.0E-87 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS02355 f91b740dc7fc95cbe61fa409628a0ed0 256 Gene3D G3DSA:3.20.20.70 1 256 8.2E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS02355 f91b740dc7fc95cbe61fa409628a0ed0 256 SUPERFAMILY SSF51366 1 250 2.35E-86 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS02355 f91b740dc7fc95cbe61fa409628a0ed0 256 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 43 56 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS02355 f91b740dc7fc95cbe61fa409628a0ed0 256 Pfam PF00290 Tryptophan synthase alpha chain 9 253 8.6E-92 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS13040 a8b9682de8824e5c4beafce1655acfb4 371 Pfam PF00005 ABC transporter 17 160 3.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS13040 a8b9682de8824e5c4beafce1655acfb4 371 Gene3D G3DSA:3.40.50.300 1 371 3.0E-71 T 29-03-2018 HVS_RS13040 a8b9682de8824e5c4beafce1655acfb4 371 SUPERFAMILY SSF52540 1 223 8.15E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13040 a8b9682de8824e5c4beafce1655acfb4 371 SMART SM00382 26 207 6.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 Gene3D G3DSA:1.10.287.950 154 251 4.0E-4 T 29-03-2018 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 SMART SM00304 144 196 1.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 Pfam PF00672 HAMP domain 149 192 1.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 Gene3D G3DSA:3.30.450.20 4 123 1.6E-16 T 29-03-2018 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 Gene3D G3DSA:1.10.287.950 252 333 1.2E-7 T 29-03-2018 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 SUPERFAMILY SSF58104 164 198 3.4E-17 T 29-03-2018 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 SUPERFAMILY SSF58104 231 330 3.4E-17 T 29-03-2018 HVS_RS16145 882828c97fc1cdc9803653d50cd1a438 338 Pfam PF02743 Cache domain 12 106 9.1E-14 T 29-03-2018 IPR033479 Double Cache domain 1 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 331 1.5E-92 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF00623 RNA polymerase Rpb1, domain 2 382 474 6.6E-29 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 386 1.2E-9 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Gene3D G3DSA:2.40.50.100 888 1005 3.8E-45 T 29-03-2018 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 SMART SM00663 224 503 9.0E-188 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF05000 RNA polymerase Rpb1, domain 4 669 736 3.4E-13 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 639 6.7E-32 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF04998 RNA polymerase Rpb1, domain 5 746 962 1.2E-49 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Pfam PF04998 RNA polymerase Rpb1, domain 5 948 1105 3.3E-18 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Gene3D G3DSA:2.40.40.20 335 477 6.2E-39 T 29-03-2018 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1164 18.794 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 SUPERFAMILY SSF64484 5 1156 0.0 T 29-03-2018 HVS_RS12950 19e49527bd4140a36cd7e48d4e90580a 1166 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 9 1158 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 Gene3D G3DSA:1.10.10.60 428 474 1.9E-13 T 29-03-2018 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 SUPERFAMILY SSF46689 429 476 6.09E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 Pfam PF12833 Helix-turn-helix domain 449 526 7.4E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 SUPERFAMILY SSF52172 1 133 2.28E-33 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 494 509 8.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 509 525 8.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 Pfam PF00072 Response regulator receiver domain 4 117 9.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 SMART SM00448 2 117 8.4E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 479 521 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 SMART SM00342 442 525 2.2E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 Gene3D G3DSA:3.40.50.2300 1 427 1.3E-35 T 29-03-2018 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 SUPERFAMILY SSF46689 478 527 6.09E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS02290 da591d61b9b1bf31c9e7162ae8de9af0 531 Gene3D G3DSA:1.10.10.60 475 530 5.0E-14 T 29-03-2018 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 330 2.0E-34 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 12 235 1.7E-118 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 Gene3D G3DSA:1.10.10.10 257 327 1.2E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 Gene3D G3DSA:3.40.50.300 18 181 3.0E-31 T 29-03-2018 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 SUPERFAMILY SSF46785 256 328 5.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 4.0E-148 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 330 171.615 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 Gene3D G3DSA:1.10.8.60 184 254 5.9E-31 T 29-03-2018 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 4.5E-35 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 SMART SM00382 51 178 9.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11510 2aafae12d657eb01e5aaf63b13276c4d 330 SUPERFAMILY SSF52540 20 249 1.43E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 SUPERFAMILY SSF52029 183 374 1.29E-84 T 29-03-2018 IPR027409 GroEL-like apical domain HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 PRINTS PR00298 60kDa chaperonin signature 348 373 1.5E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 PRINTS PR00298 60kDa chaperonin signature 396 417 1.5E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 PRINTS PR00298 60kDa chaperonin signature 26 52 1.5E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 PRINTS PR00298 60kDa chaperonin signature 266 289 1.5E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 PRINTS PR00298 60kDa chaperonin signature 82 109 1.5E-72 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 SUPERFAMILY SSF48592 6 133 2.17E-82 T 29-03-2018 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 SUPERFAMILY SSF48592 404 520 2.17E-82 T 29-03-2018 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 2.0E-259 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 Gene3D G3DSA:3.50.7.10 201 371 3.7E-96 T 29-03-2018 IPR027409 GroEL-like apical domain HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 Gene3D G3DSA:1.10.560.10 372 515 6.5E-31 T 29-03-2018 IPR027413 GroEL-like equatorial domain HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 SUPERFAMILY SSF54849 137 205 1.51E-24 T 29-03-2018 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 Gene3D G3DSA:1.10.560.10 1 200 8.0E-33 T 29-03-2018 IPR027413 GroEL-like equatorial domain HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.991 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 HVS_RS15225 2358ecf487c63be6ee056682acfbc1f2 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.4E-104 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 ProSitePatterns PS00770 Aminotransferases class-IV signature. 232 261 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 Gene3D G3DSA:3.20.10.10 174 351 4.8E-51 T 29-03-2018 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 PIRSF PIRSF006468 2 355 6.6E-132 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 43 355 3.3E-124 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 Gene3D G3DSA:3.30.470.10 2 173 2.2E-67 T 29-03-2018 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 SUPERFAMILY SSF56752 3 352 1.2E-114 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 HVS_RS07690 4bf928643448edd36c4670287c2494d8 355 Pfam PF01063 Amino-transferase class IV 69 311 1.3E-33 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 HVS_RS02565 cc9c3b320f9ed515e6f4fc8df35c28da 321 SMART SM00028 26 59 8.3E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS02565 cc9c3b320f9ed515e6f4fc8df35c28da 321 Pfam PF00515 Tetratricopeptide repeat 26 59 6.1E-8 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HVS_RS02565 cc9c3b320f9ed515e6f4fc8df35c28da 321 SUPERFAMILY SSF48452 14 93 5.06E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS02565 cc9c3b320f9ed515e6f4fc8df35c28da 321 Gene3D G3DSA:1.25.40.10 9 270 1.6E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS06755 6cb9a7b4e792e21d706f663b886d5fe1 328 SUPERFAMILY SSF55383 52 135 9.94E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06755 6cb9a7b4e792e21d706f663b886d5fe1 328 Pfam PF07833 Copper amine oxidase N-terminal domain 49 141 1.2E-32 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06755 6cb9a7b4e792e21d706f663b886d5fe1 328 Gene3D G3DSA:3.30.457.10 62 122 2.8E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06755 6cb9a7b4e792e21d706f663b886d5fe1 328 Gene3D G3DSA:3.30.457.10 9 61 6.7E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06755 6cb9a7b4e792e21d706f663b886d5fe1 328 Gene3D G3DSA:3.30.457.10 123 280 2.9E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Pfam PF01624 MutS domain I 5 116 7.6E-48 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Gene3D G3DSA:1.10.1420.10 412 539 2.2E-32 T 29-03-2018 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Pfam PF05188 MutS domain II 125 256 8.0E-19 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 694 710 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 SUPERFAMILY SSF48334 270 567 5.23E-92 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 SUPERFAMILY SSF53150 114 283 1.57E-36 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Gene3D G3DSA:3.30.420.110 129 265 6.1E-25 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Pfam PF05192 MutS domain III 272 563 7.5E-46 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Gene3D G3DSA:3.40.50.300 571 839 1.1E-49 T 29-03-2018 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Pfam PF00488 MutS domain V 617 805 8.9E-86 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 867 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 SMART SM00533 287 595 2.5E-108 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 861 26.017 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 SUPERFAMILY SSF55271 2 112 2.09E-45 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Gene3D G3DSA:1.10.1420.10 266 411 3.3E-39 T 29-03-2018 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 SUPERFAMILY SSF52540 571 806 2.99E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Pfam PF05190 MutS family domain IV 432 523 3.0E-32 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 Gene3D G3DSA:3.40.1170.10 1 128 2.8E-51 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 PIRSF PIRSF037677 1 854 2.2E-184 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 HVS_RS08425 f12ed6d176d96e9541aa9ef82a08bdc2 873 SMART SM00534 613 802 6.6E-120 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 SUPERFAMILY SSF46785 1 81 1.57E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 PIRSF PIRSF019345 1 211 2.1E-52 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 186 29.365 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 Gene3D G3DSA:1.10.10.10 1 84 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 166 2.9E-52 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 Gene3D G3DSA:1.10.10.10 85 177 1.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 179 6.1E-45 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HVS_RS08230 bf64050b6b231b896787fad14de6bbf9 218 SUPERFAMILY SSF46785 85 159 4.79E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 Pfam PF00365 Phosphofructokinase 12 289 5.0E-57 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 259 281 5.9E-9 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 10 29 5.9E-9 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 155 5.9E-9 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 178 194 5.9E-9 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 SUPERFAMILY SSF53784 11 409 3.4E-104 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 PIRSF PIRSF036483 4 413 8.3E-157 T 29-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 Gene3D G3DSA:3.40.50.450 3 236 1.5E-53 T 29-03-2018 HVS_RS12360 75a3da8fd62439688ab354c1953b042f 413 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 5 400 44.849 T 29-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 HVS_RS02365 5fefac1fc3cb773043eb86c96a019ceb 221 Gene3D G3DSA:1.10.101.10 23 102 1.7E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS02365 5fefac1fc3cb773043eb86c96a019ceb 221 Pfam PF01471 Putative peptidoglycan binding domain 39 93 5.0E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS02365 5fefac1fc3cb773043eb86c96a019ceb 221 Pfam PF07486 Cell Wall Hydrolase 118 220 2.0E-28 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HVS_RS02365 5fefac1fc3cb773043eb86c96a019ceb 221 SUPERFAMILY SSF47090 31 100 1.7E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Gene3D G3DSA:2.60.40.1380 273 413 2.3E-10 T 29-03-2018 HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Gene3D G3DSA:3.40.50.410 31 260 1.5E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Gene3D G3DSA:2.60.40.1080 494 583 6.1E-16 T 29-03-2018 HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF12733 Cadherin-like beta sandwich domain 606 681 6.9E-10 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF02368 Bacterial Ig-like domain (group 2) 361 400 1.2E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF02368 Bacterial Ig-like domain (group 2) 498 576 5.7E-10 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF00395 S-layer homology domain 824 868 1.4E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF00395 S-layer homology domain 704 745 5.3E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF00395 S-layer homology domain 764 806 1.5E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 SUPERFAMILY SSF53300 37 194 6.5E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 SMART SM00327 37 221 0.0012 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 SMART SM00635 497 577 2.7E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 SMART SM00635 335 408 0.89 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 SUPERFAMILY SSF49373 362 409 1.37E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Pfam PF00092 von Willebrand factor type A domain 39 188 3.2E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 SUPERFAMILY SSF49373 496 580 8.63E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments HVS_RS01900 b4f784fd0e75b0cdd5399c5b68dd5445 877 Gene3D G3DSA:2.60.40.1080 415 493 7.4E-6 T 29-03-2018 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 300 41.456 T 29-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 Pfam PF01180 Dihydroorotate dehydrogenase 4 285 7.9E-78 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 299 2.1E-114 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 238 258 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 Gene3D G3DSA:3.20.20.70 1 301 1.1E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 PIRSF PIRSF000164 1 301 5.0E-85 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 HVS_RS08890 ecd3fb737c5559105d525a90a66c0db9 303 SUPERFAMILY SSF51395 1 300 9.66E-91 T 29-03-2018 HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 Pfam PF11104 Type IV pilus assembly protein PilM; 15 362 4.8E-34 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 Gene3D G3DSA:3.30.420.40 1 171 1.2E-21 T 29-03-2018 HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 SUPERFAMILY SSF53067 204 348 1.54E-22 T 29-03-2018 HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 SMART SM00842 12 176 0.0079 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 SUPERFAMILY SSF53067 12 171 6.2E-11 T 29-03-2018 HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 Gene3D G3DSA:3.30.420.40 204 341 1.5E-13 T 29-03-2018 HVS_RS07855 0a71ce15593e32a774723f1383616a95 370 PIRSF PIRSF019169 1 370 1.1E-96 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 SUPERFAMILY SSF88659 118 184 9.72E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 Gene3D G3DSA:1.10.10.10 122 185 3.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 Pfam PF04542 Sigma-70 region 2 37 100 6.8E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 183 2.9E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 SUPERFAMILY SSF88946 13 111 7.26E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 Pfam PF08281 Sigma-70, region 4 130 175 3.3E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09895 5e46730121ba5d9a282b27d4bb027ca0 185 Gene3D G3DSA:1.10.1740.10 8 121 1.1E-20 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Pfam PF14520 Helix-hairpin-helix domain 439 493 3.9E-5 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SMART SM00292 588 662 8.8E-13 T 29-03-2018 IPR001357 BRCT domain HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:1.10.150.20 425 496 1.2E-25 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:3.40.50.10190 609 662 1.2E-19 T 29-03-2018 IPR001357 BRCT domain HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SUPERFAMILY SSF47781 397 578 4.82E-55 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 589 662 7.1E-17 T 29-03-2018 IPR001357 BRCT domain HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:1.10.150.20 547 608 9.5E-10 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Hamap MF_01588 DNA ligase [ligA]. 1 662 52.097 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 PIRSF PIRSF001604 1 663 3.7E-258 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:1.10.287.610 1 66 7.0E-28 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SMART SM00278 539 558 6.6 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SMART SM00278 439 458 9.6 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SMART SM00278 475 494 0.2 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SMART SM00532 2 441 7.5E-265 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Pfam PF12826 Helix-hairpin-helix motif 505 568 2.6E-17 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 315 392 3.0E-34 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 312 5.7E-127 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:3.30.1490.70 233 315 4.7E-26 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:3.30.470.30 116 232 7.7E-50 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 10 658 2.3E-259 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:1.10.150.20 497 546 2.0E-14 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 112 141 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Gene3D G3DSA:2.40.50.140 316 383 7.6E-32 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 401 427 5.1E-10 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SUPERFAMILY SSF50249 312 395 1.88E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SUPERFAMILY SSF56091 3 310 1.28E-119 T 29-03-2018 HVS_RS07215 cf840caad366a56f0ca49744b75daf08 663 SUPERFAMILY SSF52113 586 662 2.13E-20 T 29-03-2018 IPR001357 BRCT domain HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 Gene3D G3DSA:1.10.287.470 191 219 0.013 T 29-03-2018 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 Gene3D G3DSA:2.40.50.100 63 132 2.1E-15 T 29-03-2018 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 SUPERFAMILY SSF111369 193 333 4.58E-17 T 29-03-2018 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 329 2.5E-28 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 SUPERFAMILY SSF56954 134 196 1.27E-6 T 29-03-2018 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 Gene3D G3DSA:2.40.50.100 220 398 1.0E-4 T 29-03-2018 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 SUPERFAMILY SSF111369 52 121 7.59E-13 T 29-03-2018 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 199 409 2.3E-47 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 HVS_RS05905 66e4c50bc7480144888ef4176f450574 411 Gene3D G3DSA:1.10.287.470 133 188 1.1E-8 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 Gene3D G3DSA:3.40.50.20 138 232 4.9E-15 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 SUPERFAMILY SSF46548 9 151 2.25E-37 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 19 127 7.7E-45 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 PRINTS PR00419 Adrenodoxin reductase family signature 283 297 6.5E-18 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 PRINTS PR00419 Adrenodoxin reductase family signature 317 330 6.5E-18 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 PRINTS PR00419 Adrenodoxin reductase family signature 142 164 6.5E-18 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 PRINTS PR00419 Adrenodoxin reductase family signature 165 178 6.5E-18 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 141 449 2.2E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 16 460 2.2E-187 T 29-03-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 SUPERFAMILY SSF51971 140 394 8.24E-69 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 Gene3D G3DSA:1.10.1060.10 3 137 4.0E-47 T 29-03-2018 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 Gene3D G3DSA:3.50.50.60 295 464 1.8E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS11205 742e189d34e16217da73e1d3e9727c99 464 Gene3D G3DSA:3.50.50.60 233 294 2.5E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 Gene3D G3DSA:3.40.50.720 1 37 1.5E-7 T 29-03-2018 HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 Gene3D G3DSA:3.40.50.720 38 244 1.8E-65 T 29-03-2018 HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.4E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 242 5.3E-66 T 29-03-2018 HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.6E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.6E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.6E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.6E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.6E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.6E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS13735 c7f422b0ffdbc20ee00cb028fc39e114 244 SUPERFAMILY SSF51735 2 243 2.28E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 142 1.5E-48 T 29-03-2018 HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 Gene3D G3DSA:3.40.50.300 180 448 3.0E-23 T 29-03-2018 HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 SMART SM00382 213 396 3.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 SUPERFAMILY SSF54211 11 170 9.48E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 10 502 6.4E-194 T 29-03-2018 IPR004482 Mg chelatase-related protein HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 407 502 3.5E-33 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 Gene3D G3DSA:3.30.230.10 2 179 5.6E-51 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 SUPERFAMILY SSF52540 191 507 2.44E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10295 b0ec4db0318a16462e52252da2f9a035 512 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 399 2.0E-94 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain HVS_RS05455 0098fe5140848c591cbb73723690be04 204 Gene3D G3DSA:2.40.10.220 85 204 3.2E-14 T 29-03-2018 HVS_RS05455 0098fe5140848c591cbb73723690be04 204 SUPERFAMILY SSF141371 88 201 1.14E-11 T 29-03-2018 HVS_RS05455 0098fe5140848c591cbb73723690be04 204 Pfam PF07238 PilZ domain 91 187 1.3E-12 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS04225 26a65d59f7f4ca1235234f0c217b1c84 61 Pfam PF05717 IS66 Orf2 like protein 5 49 2.7E-11 T 29-03-2018 IPR008878 Transposase IS66, Orf2 HVS_RS04115 77dfdedc69dd7ad3deba270a2ab729fd 242 Pfam PF04474 Protein of unknown function (DUF554) 5 235 8.1E-79 T 29-03-2018 IPR007563 Protein of unknown function DUF554 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 236 1.1E-84 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 Pfam PF01728 FtsJ-like methyltransferase 60 239 8.9E-20 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 PIRSF PIRSF005578 1 262 7.5E-105 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 SUPERFAMILY SSF53335 50 248 4.98E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 SMART SM00363 4 69 7.1E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 Gene3D G3DSA:3.40.50.150 63 266 2.6E-58 T 29-03-2018 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 Gene3D G3DSA:3.10.290.10 1 62 6.4E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 Pfam PF01479 S4 domain 4 47 6.6E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08600 2199b5b4fd70d0c1093b7f316e78fe05 266 SUPERFAMILY SSF55174 3 69 5.59E-14 T 29-03-2018 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 Hamap MF_00455 Xylose isomerase [xylA]. 11 436 55.386 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 300 311 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 156 175 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 180 201 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 271 298 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 92 114 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 133 153 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 207 226 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 333 344 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 PRINTS PR00688 Xylose isomerase signature 229 253 1.5E-95 T 29-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 Pfam PF01261 Xylose isomerase-like TIM barrel 88 275 1.9E-7 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 4 436 2.4E-229 T 29-03-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 Gene3D G3DSA:3.20.20.150 2 439 2.2E-118 T 29-03-2018 HVS_RS02325 d8da26c47ce98a0bc37a1d07dfd4ac80 439 SUPERFAMILY SSF51658 3 437 2.8E-177 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 53.784 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 6 407 3.1E-209 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 Gene3D G3DSA:1.10.8.60 312 403 7.1E-36 T 29-03-2018 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 SUPERFAMILY SSF57716 10 45 3.14E-11 T 29-03-2018 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 Pfam PF07724 AAA domain (Cdc48 subfamily) 108 305 4.1E-49 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 SMART SM00382 108 271 6.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 SUPERFAMILY SSF52540 59 400 2.34E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 Gene3D G3DSA:3.40.50.300 53 310 1.7E-71 T 29-03-2018 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 4.8E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 SMART SM00994 9 48 9.7E-23 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 SMART SM01086 312 406 1.5E-35 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS12880 63037939f79c843b36d4eb2b3128230b 429 Pfam PF06689 ClpX C4-type zinc finger 11 47 3.9E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 SUPERFAMILY SSF52266 91 196 3.02E-73 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 SUPERFAMILY SSF52266 400 580 3.02E-73 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 400 517 3.7E-14 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 92 211 1.3E-8 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 SUPERFAMILY SSF49785 232 353 1.7E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 Gene3D G3DSA:3.40.50.1110 91 524 3.2E-75 T 29-03-2018 HVS_RS03335 effdf518a77ec22d1acba8b9e40276a5 630 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 261 362 5.9E-7 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HVS_RS01575 081f40dedd6a9c9d908344ab2b412dcf 86 SUPERFAMILY SSF143120 2 75 1.18E-13 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HVS_RS01575 081f40dedd6a9c9d908344ab2b412dcf 86 Gene3D G3DSA:3.40.1620.10 2 49 5.0E-9 T 29-03-2018 HVS_RS01575 081f40dedd6a9c9d908344ab2b412dcf 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 47 2.7E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HVS_RS13520 b472a5cb626809f6c667a5a132ffe858 139 Pfam PF05105 Bacteriophage holin family 18 129 6.8E-42 T 29-03-2018 IPR006480 Bacteriophage holin family HVS_RS13520 b472a5cb626809f6c667a5a132ffe858 139 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 14 138 3.6E-29 T 29-03-2018 IPR006480 Bacteriophage holin family HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Gene3D G3DSA:3.30.565.10 14 231 3.0E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 153 1.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Gene3D G3DSA:3.40.50.670 415 653 1.4E-72 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 589 605 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 436 450 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 549 561 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 74 87 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 120 134 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 529 546 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 39 54 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR00418 DNA topoisomerase II family signature 511 527 3.2E-35 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Pfam PF00204 DNA gyrase B 228 403 6.8E-31 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 SMART SM00387 35 156 0.0016 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 ProSitePatterns PS00177 DNA topoisomerase II signature. 438 446 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Pfam PF01751 Toprim domain 435 546 4.8E-17 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 SUPERFAMILY SSF54211 228 403 1.76E-22 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 227 249 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 203 216 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 626 642 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 10 20 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 374 388 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 486 495 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 388 408 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 PRINTS PR01159 DNA gyrase subunit B signature 610 622 6.4E-20 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Gene3D G3DSA:3.30.230.10 232 404 1.5E-24 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 SUPERFAMILY SSF56719 418 648 2.41E-63 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 585 646 1.0E-21 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 SUPERFAMILY SSF55874 9 225 3.14E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05220 6c061536ea657ddb2fd7cdee4430f7c9 659 SMART SM00433 39 650 4.5E-104 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 164 192 - T 29-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 Pfam PF00482 Type II secretion system (T2SS), protein F 273 394 5.5E-24 T 29-03-2018 IPR018076 Type II secretion system F domain HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 Pfam PF00482 Type II secretion system (T2SS), protein F 69 192 4.5E-32 T 29-03-2018 IPR018076 Type II secretion system F domain HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 Gene3D G3DSA:3.30.70.1120 98 164 0.0035 T 29-03-2018 HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 1.7E-20 T 29-03-2018 IPR003004 GspF/PilC family HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 1.7E-20 T 29-03-2018 IPR003004 GspF/PilC family HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 1.7E-20 T 29-03-2018 IPR003004 GspF/PilC family HVS_RS09995 df745cd80a61496cd1e86835e8af30e7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 1.7E-20 T 29-03-2018 IPR003004 GspF/PilC family HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 SUPERFAMILY SSF55831 3 270 2.09E-88 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 Gene3D G3DSA:3.30.572.10 1 276 3.0E-91 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 PRINTS PR00108 Thymidylate synthase family signature 55 76 2.0E-23 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 PRINTS PR00108 Thymidylate synthase family signature 126 145 2.0E-23 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 PRINTS PR00108 Thymidylate synthase family signature 152 167 2.0E-23 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 PRINTS PR00108 Thymidylate synthase family signature 170 196 2.0E-23 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 PRINTS PR00108 Thymidylate synthase family signature 208 225 2.0E-23 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 95 275 2.3E-50 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 Hamap MF_00008 Thymidylate synthase [thyA]. 5 276 32.769 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 Pfam PF00303 Thymidylate synthase 8 271 9.5E-85 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS10580 1b58e8aaaa9c5a4abcd47ba6fd139fd5 276 ProSitePatterns PS00091 Thymidylate synthase active site. 137 165 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS01370 066354374c446139c67c3ac7a301050e 95 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 17 89 1.0E-14 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HVS_RS01370 066354374c446139c67c3ac7a301050e 95 SUPERFAMILY SSF101498 14 89 2.09E-15 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HVS_RS01370 066354374c446139c67c3ac7a301050e 95 Pfam PF04316 Anti-sigma-28 factor, FlgM 34 87 1.3E-17 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal HVS_RS01370 066354374c446139c67c3ac7a301050e 95 Gene3D G3DSA:1.10.287.1160 59 88 1.6E-9 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 HVS_RS10855 7a2dd1be6a13047c7d28ce42628b859f 128 PIRSF PIRSF016789 8 128 9.8E-37 T 29-03-2018 IPR007401 Protein of unknown function DUF454 HVS_RS10855 7a2dd1be6a13047c7d28ce42628b859f 128 Pfam PF04304 Protein of unknown function (DUF454) 10 125 3.6E-37 T 29-03-2018 IPR007401 Protein of unknown function DUF454 HVS_RS01685 ee4d54b1defd4e008d43037b2639fb90 264 Pfam PF00691 OmpA family 157 256 1.1E-19 T 29-03-2018 IPR006665 OmpA-like domain HVS_RS01685 ee4d54b1defd4e008d43037b2639fb90 264 Gene3D G3DSA:3.30.1330.60 95 264 1.4E-39 T 29-03-2018 IPR006665 OmpA-like domain HVS_RS01685 ee4d54b1defd4e008d43037b2639fb90 264 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 5 60 1.7E-24 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain HVS_RS01685 ee4d54b1defd4e008d43037b2639fb90 264 SUPERFAMILY SSF103088 138 262 1.05E-29 T 29-03-2018 IPR006665 OmpA-like domain HVS_RS06350 25f43a3046dbd0e4aa22a206f6303420 236 Pfam PF00696 Amino acid kinase family 7 213 2.7E-30 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS06350 25f43a3046dbd0e4aa22a206f6303420 236 PIRSF PIRSF005650 1 236 2.7E-97 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 HVS_RS06350 25f43a3046dbd0e4aa22a206f6303420 236 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 235 1.7E-95 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 HVS_RS06350 25f43a3046dbd0e4aa22a206f6303420 236 SUPERFAMILY SSF53633 4 234 3.27E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS06350 25f43a3046dbd0e4aa22a206f6303420 236 Gene3D G3DSA:3.40.1160.10 1 236 3.0E-44 T 29-03-2018 HVS_RS06350 25f43a3046dbd0e4aa22a206f6303420 236 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 235 44.011 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 447 530 1.6E-9 T 29-03-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 SUPERFAMILY SSF51011 440 532 8.91E-11 T 29-03-2018 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 Gene3D G3DSA:2.60.40.1180 439 533 7.8E-26 T 29-03-2018 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 Gene3D G3DSA:3.20.20.80 128 438 2.3E-45 T 29-03-2018 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 Pfam PF00404 Dockerin type I repeat 84 104 3.5E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 SUPERFAMILY SSF63446 45 113 5.0E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 SUPERFAMILY SSF51445 130 446 9.53E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 190 265 1.8E-7 T 29-03-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 HVS_RS09025 f438e69654c7ee9860466c3ae8e9da42 533 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 84 103 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS02650 004202d8b12ba91f0fae98c0a840eb4d 269 Gene3D G3DSA:3.40.50.720 1 251 8.8E-73 T 29-03-2018 HVS_RS02650 004202d8b12ba91f0fae98c0a840eb4d 269 SUPERFAMILY SSF69572 2 263 7.19E-96 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HVS_RS02650 004202d8b12ba91f0fae98c0a840eb4d 269 Pfam PF00899 ThiF family 11 246 7.6E-65 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HVS_RS09470 52b22d705278f6a81f456bc2a9df02e3 247 Pfam PF06271 RDD family 19 154 1.8E-16 T 29-03-2018 IPR010432 RDD HVS_RS05630 50a7302e7251471ce3593570781bd0d2 86 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 15 85 2.5E-6 T 29-03-2018 IPR024962 YukD-like HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF46915 224 323 3.14E-26 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Pfam PF00013 KH domain 560 614 3.7E-11 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF54211 290 487 3.95E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 692 8.1E-291 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Gene3D G3DSA:1.10.10.400 236 308 3.8E-22 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SMART SM00322 553 618 2.7E-11 T 29-03-2018 IPR004087 K Homology domain GO:0003676 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Gene3D G3DSA:2.40.50.140 616 697 3.3E-23 T 29-03-2018 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SMART SM00316 621 691 9.7E-23 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Gene3D G3DSA:3.30.1370.10 551 615 2.7E-15 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF54211 5 142 1.52E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Pfam PF00575 S1 RNA binding domain 620 691 4.6E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 694 29.665 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF55666 143 232 1.14E-24 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF54791 557 641 4.55E-23 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 317 3.9E-13 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF55666 447 548 1.66E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 SUPERFAMILY SSF50249 621 704 2.57E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Gene3D G3DSA:3.30.230.70 10 235 5.4E-43 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Gene3D G3DSA:3.30.230.70 309 550 9.4E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Pfam PF01138 3' exoribonuclease family, domain 1 320 453 7.3E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 2.5E-17 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 PIRSF PIRSF005499 1 710 2.9E-283 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HVS_RS10025 19589569e68b6d7d638a217cd8be7bb1 711 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 1.7E-10 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 359 34.819 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Gene3D G3DSA:1.10.601.10 2 69 0.0039 T 29-03-2018 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Gene3D G3DSA:1.10.601.10 70 195 2.6E-78 T 29-03-2018 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Gene3D G3DSA:1.10.10.10 288 359 7.6E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Pfam PF04539 Sigma-70 region 3 205 281 8.1E-31 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Pfam PF04542 Sigma-70 region 2 126 195 2.8E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 SUPERFAMILY SSF88946 87 196 2.35E-55 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 SUPERFAMILY SSF88659 256 358 1.4E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Pfam PF03979 Sigma-70 factor, region 1.1 9 74 6.2E-18 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Pfam PF00140 Sigma-70 factor, region 1.2 88 121 4.2E-20 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 121 347 9.9E-40 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 122 358 3.9E-124 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 319 345 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 PRINTS PR00046 Major sigma-70 factor signature 319 334 2.0E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 PRINTS PR00046 Major sigma-70 factor signature 150 163 2.0E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 PRINTS PR00046 Major sigma-70 factor signature 174 182 2.0E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 PRINTS PR00046 Major sigma-70 factor signature 334 345 2.0E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 PRINTS PR00046 Major sigma-70 factor signature 298 310 2.0E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 SUPERFAMILY SSF88659 199 273 1.09E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Gene3D G3DSA:1.10.10.10 196 246 3.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 Pfam PF04545 Sigma-70, region 4 294 347 4.1E-20 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09285 d9b006a1fdb391194a82866fffbfc81f 359 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 150 163 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09065 9196094b2676d42ccb51cb14b4369f33 276 Gene3D G3DSA:3.40.50.1110 1 199 8.2E-34 T 29-03-2018 HVS_RS09065 9196094b2676d42ccb51cb14b4369f33 276 Gene3D G3DSA:1.10.1330.10 207 276 1.8E-4 T 29-03-2018 HVS_RS09065 9196094b2676d42ccb51cb14b4369f33 276 SUPERFAMILY SSF52266 1 185 6.72E-30 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS09065 9196094b2676d42ccb51cb14b4369f33 276 Pfam PF00404 Dockerin type I repeat 213 233 1.3E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09065 9196094b2676d42ccb51cb14b4369f33 276 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 3 177 1.5E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS09065 9196094b2676d42ccb51cb14b4369f33 276 SUPERFAMILY SSF63446 207 275 1.7E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS03895 c884167c9257156296212f88b241d93f 86 Pfam PF08958 Domain of unknown function (DUF1871) 9 80 3.2E-5 T 29-03-2018 IPR015053 Protein of unknown function DUF1871 HVS_RS03895 c884167c9257156296212f88b241d93f 86 Gene3D G3DSA:1.10.340.20 3 83 3.1E-22 T 29-03-2018 HVS_RS03895 c884167c9257156296212f88b241d93f 86 SUPERFAMILY SSF116922 5 81 7.06E-13 T 29-03-2018 IPR023162 Apc36109-like domain HVS_RS15630 35193577b77088fe6d861cede3134b10 486 Gene3D G3DSA:3.60.120.10 2 482 4.4E-140 T 29-03-2018 IPR005801 ADC synthase GO:0009058 HVS_RS15630 35193577b77088fe6d861cede3134b10 486 Pfam PF04715 Anthranilate synthase component I, N terminal region 21 151 7.5E-26 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS15630 35193577b77088fe6d861cede3134b10 486 Pfam PF00425 chorismate binding enzyme 219 472 2.1E-89 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HVS_RS15630 35193577b77088fe6d861cede3134b10 486 PRINTS PR00095 Anthranilate synthase component I signature 334 347 1.2E-11 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS15630 35193577b77088fe6d861cede3134b10 486 PRINTS PR00095 Anthranilate synthase component I signature 414 428 1.2E-11 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS15630 35193577b77088fe6d861cede3134b10 486 PRINTS PR00095 Anthranilate synthase component I signature 429 443 1.2E-11 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS15630 35193577b77088fe6d861cede3134b10 486 SUPERFAMILY SSF56322 12 481 3.27E-126 T 29-03-2018 IPR005801 ADC synthase GO:0009058 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 SUPERFAMILY SSF54631 127 267 1.77E-34 T 29-03-2018 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 SUPERFAMILY SSF161093 271 442 4.45E-43 T 29-03-2018 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 SMART SM00116 199 247 2.0E-10 T 29-03-2018 IPR000644 CBS domain HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 SMART SM00116 135 188 69.0 T 29-03-2018 IPR000644 CBS domain HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Pfam PF03448 MgtE intracellular N domain 26 125 4.6E-25 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Gene3D G3DSA:1.10.357.20 270 444 3.5E-37 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Pfam PF01769 Divalent cation transporter 313 435 1.9E-27 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Gene3D G3DSA:1.25.60.10 1 116 2.6E-14 T 29-03-2018 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 SUPERFAMILY SSF158791 7 125 1.57E-26 T 29-03-2018 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 SMART SM00924 25 128 1.7E-29 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 TIGRFAM TIGR00400 mgtE: magnesium transporter 7 444 1.2E-150 T 29-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Pfam PF00571 CBS domain 128 186 9.6E-6 T 29-03-2018 IPR000644 CBS domain HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Pfam PF00571 CBS domain 192 247 4.7E-12 T 29-03-2018 IPR000644 CBS domain HVS_RS01625 e455006ae90cae9f017c3af6461399bf 444 Gene3D G3DSA:3.10.580.10 117 263 3.0E-24 T 29-03-2018 HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 Pfam PF02558 Ketopantoate reductase PanE/ApbA 6 154 2.1E-37 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 5 306 5.4E-75 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 301 1.3E-29 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 Gene3D G3DSA:1.10.1040.10 180 308 2.9E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 SUPERFAMILY SSF51735 5 167 3.94E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 SUPERFAMILY SSF48179 180 302 5.78E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS15615 1db1fa0a2cc2826327616f867d789641 308 Gene3D G3DSA:3.40.50.720 1 179 8.5E-27 T 29-03-2018 HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 Gene3D G3DSA:3.10.105.10 330 545 6.8E-47 T 29-03-2018 HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 486 2.8E-83 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 Gene3D G3DSA:3.40.190.10 224 329 3.8E-21 T 29-03-2018 HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 Gene3D G3DSA:3.90.76.10 54 195 6.0E-35 T 29-03-2018 HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 SUPERFAMILY SSF53850 51 573 3.26E-109 T 29-03-2018 HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 PIRSF PIRSF002741 33 196 2.8E-34 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HVS_RS09365 4426942bf9a4cd507ef861c2b0ffd83a 576 PIRSF PIRSF002741 210 575 8.5E-71 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HVS_RS01345 d0fb28f97d916b73ae370477f4d4f5d4 441 SUPERFAMILY SSF52540 1 154 1.07E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01345 d0fb28f97d916b73ae370477f4d4f5d4 441 SUPERFAMILY SSF52540 249 406 1.07E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01345 d0fb28f97d916b73ae370477f4d4f5d4 441 Gene3D G3DSA:3.40.50.300 1 410 1.1E-22 T 29-03-2018 HVS_RS01345 d0fb28f97d916b73ae370477f4d4f5d4 441 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 30 371 4.6E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 564 1.5E-147 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Gene3D G3DSA:3.40.50.620 113 370 1.6E-57 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 SUPERFAMILY SSF52374 122 455 5.35E-93 T 29-03-2018 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Hamap MF_00123 Arginine--tRNA ligase [argS]. 14 564 26.808 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Pfam PF05746 DALR anticodon binding domain 444 564 3.5E-35 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 SMART SM01016 10 99 7.2E-37 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Gene3D G3DSA:3.30.1360.70 4 112 4.2E-33 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 138 147 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Gene3D G3DSA:1.10.730.10 410 564 1.1E-48 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 12 99 3.9E-26 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 SUPERFAMILY SSF47323 439 564 1.05E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 Pfam PF00750 tRNA synthetases class I (R) 121 411 3.3E-22 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 SUPERFAMILY SSF55190 12 119 6.28E-27 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 PRINTS PR01038 Arginyl-tRNA synthetase signature 143 159 2.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 143 2.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 PRINTS PR01038 Arginyl-tRNA synthetase signature 312 333 2.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 PRINTS PR01038 Arginyl-tRNA synthetase signature 167 180 2.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 HVS_RS01745 ab68d98754655d2c1d3978b2c47cd24a 564 SMART SM00836 444 564 1.3E-58 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HVS_RS14690 5a9ea81020ef1b69ff469901bcdebdcc 125 Pfam PF02152 Dihydroneopterin aldolase 7 118 1.1E-32 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HVS_RS14690 5a9ea81020ef1b69ff469901bcdebdcc 125 TIGRFAM TIGR00526 folB_dom: FolB domain 5 124 1.0E-30 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HVS_RS14690 5a9ea81020ef1b69ff469901bcdebdcc 125 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 6 120 3.9E-33 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HVS_RS14690 5a9ea81020ef1b69ff469901bcdebdcc 125 SMART SM00905 7 120 1.8E-42 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 HVS_RS14690 5a9ea81020ef1b69ff469901bcdebdcc 125 SUPERFAMILY SSF55620 5 122 6.99E-35 T 29-03-2018 HVS_RS14690 5a9ea81020ef1b69ff469901bcdebdcc 125 Gene3D G3DSA:3.30.1130.10 4 123 1.9E-32 T 29-03-2018 HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 426 445 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 53 333 8.9E-75 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 165 174 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 SUPERFAMILY SSF51445 26 365 1.6E-88 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 SUPERFAMILY SSF63446 386 455 4.12E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 Gene3D G3DSA:3.20.20.80 17 366 2.2E-52 T 29-03-2018 HVS_RS09445 6f1bf9a00f642c2fe8a4ec998835ac75 456 Gene3D G3DSA:1.10.1330.10 384 456 6.6E-5 T 29-03-2018 HVS_RS06985 5b2ce432b2e1d4febc010262478a8d49 203 Gene3D G3DSA:3.20.20.370 24 196 4.4E-44 T 29-03-2018 HVS_RS06985 5b2ce432b2e1d4febc010262478a8d49 203 Pfam PF01522 Polysaccharide deacetylase 51 167 1.9E-35 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HVS_RS06985 5b2ce432b2e1d4febc010262478a8d49 203 SUPERFAMILY SSF88713 42 189 4.0E-47 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 Gene3D G3DSA:1.50.10.10 38 399 1.7E-106 T 29-03-2018 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 645 664 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 SUPERFAMILY SSF48208 42 397 5.53E-97 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 Pfam PF00404 Dockerin type I repeat 645 665 6.1E-7 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 Pfam PF03425 Carbohydrate binding domain (family 11) 430 595 1.2E-36 T 29-03-2018 IPR005087 Carbohydrate binding module family 11 GO:0008810|GO:0030245 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 PRINTS PR00735 Glycosyl hydrolase family 8 signature 97 110 2.5E-39 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 PRINTS PR00735 Glycosyl hydrolase family 8 signature 154 172 2.5E-39 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 PRINTS PR00735 Glycosyl hydrolase family 8 signature 215 232 2.5E-39 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 PRINTS PR00735 Glycosyl hydrolase family 8 signature 375 389 2.5E-39 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 PRINTS PR00735 Glycosyl hydrolase family 8 signature 278 287 2.5E-39 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 PRINTS PR00735 Glycosyl hydrolase family 8 signature 257 268 2.5E-39 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 ProSitePatterns PS00018 EF-hand calcium-binding domain. 612 624 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 SUPERFAMILY SSF49785 432 590 8.5E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 Pfam PF01270 Glycosyl hydrolases family 8 43 388 5.8E-98 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 Gene3D G3DSA:1.10.1330.10 609 675 1.0E-6 T 29-03-2018 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 Gene3D G3DSA:2.60.120.430 425 591 3.5E-26 T 29-03-2018 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 ProSitePatterns PS00812 Glycosyl hydrolases family 8 signature. 154 172 - T 29-03-2018 IPR019834 Glycoside hydrolase, family 8, conserved site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS12430 95a334dfd44008ca3cff33993d627358 675 SUPERFAMILY SSF63446 609 674 2.49E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 Gene3D G3DSA:3.90.930.12 84 179 2.1E-41 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 SUPERFAMILY SSF56053 1 83 6.0E-26 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 Gene3D G3DSA:3.90.930.12 2 83 5.1E-29 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 PIRSF PIRSF002162 1 178 6.6E-50 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 Pfam PF00347 Ribosomal protein L6 92 165 7.6E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 Pfam PF00347 Ribosomal protein L6 11 83 1.9E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.7E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.7E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.7E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 SUPERFAMILY SSF56053 84 178 1.67E-36 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.115 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HVS_RS15065 45df48ba6a2b9335d5f45547c424394b 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 5.9E-75 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HVS_RS05305 707d738d44d23446753876801c2e88f8 150 Pfam PF04024 PspC domain 3 60 5.1E-23 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 SUPERFAMILY SSF81271 9 68 1.67E-7 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 294 491 1.8E-18 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 SMART SM00382 291 452 1.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 Gene3D G3DSA:3.40.50.300 217 524 4.0E-45 T 29-03-2018 HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 Gene3D G3DSA:3.10.20.30 6 68 1.0E-8 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 SUPERFAMILY SSF55186 71 240 4.84E-38 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 SUPERFAMILY SSF52540 291 556 3.25E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02715 6c53ba56d5f8d6955af36b13da6d982f 557 Gene3D G3DSA:3.30.980.10 75 209 4.0E-19 T 29-03-2018 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 Pfam PF01018 GTP1/OBG 3 157 1.4E-59 T 29-03-2018 IPR006169 GTP1/OBG domain HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 Gene3D G3DSA:3.40.50.300 155 409 1.3E-33 T 29-03-2018 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 355 423 1.6E-21 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 SUPERFAMILY SSF102741 352 423 1.02E-18 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 Hamap MF_01454 GTPase Obg [obg]. 1 330 48.261 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 PIRSF PIRSF002401 1 372 1.7E-140 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 Gene3D G3DSA:2.70.210.12 1 154 6.5E-59 T 29-03-2018 IPR006169 GTP1/OBG domain HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 SUPERFAMILY SSF52540 160 334 8.93E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 Pfam PF09269 Domain of unknown function (DUF1967) 355 422 2.0E-24 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 ProSitePatterns PS00905 GTP1/OBG family signature. 211 224 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 324 3.4E-12 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 SUPERFAMILY SSF82051 2 157 3.66E-54 T 29-03-2018 IPR006169 GTP1/OBG domain HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 Pfam PF01926 50S ribosome-binding GTPase 160 282 1.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 329 7.9E-140 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 224 1.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 226 244 1.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS11550 b4a129e766a79fd76f2f42225d2f5727 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.0E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 SUPERFAMILY SSF55347 150 314 1.18E-55 T 29-03-2018 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 Gene3D G3DSA:3.40.50.720 1 161 3.9E-42 T 29-03-2018 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 Gene3D G3DSA:3.30.360.10 162 314 1.0E-58 T 29-03-2018 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 344 6.5E-133 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 315 6.2E-18 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 SUPERFAMILY SSF51735 2 174 3.91E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 340 42.382 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 142 1.4E-35 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HVS_RS14360 2f6d4214f61fa37e621b4c6e511085d0 346 SMART SM00859 3 142 8.2E-56 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HVS_RS12045 8f1f7606a6c7b9c51fbd33ca6e7a26f6 275 Gene3D G3DSA:3.40.630.30 107 267 1.1E-56 T 29-03-2018 HVS_RS12045 8f1f7606a6c7b9c51fbd33ca6e7a26f6 275 PIRSF PIRSF018688 1 275 1.9E-82 T 29-03-2018 IPR016732 Uncharacterised conserved protein UCP018688 HVS_RS12045 8f1f7606a6c7b9c51fbd33ca6e7a26f6 275 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 3 273 5.6E-48 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal HVS_RS12045 8f1f7606a6c7b9c51fbd33ca6e7a26f6 275 Gene3D G3DSA:3.40.630.30 1 106 1.6E-25 T 29-03-2018 HVS_RS12045 8f1f7606a6c7b9c51fbd33ca6e7a26f6 275 SUPERFAMILY SSF55729 115 274 4.4E-51 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS12045 8f1f7606a6c7b9c51fbd33ca6e7a26f6 275 SUPERFAMILY SSF55729 2 114 3.18E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 SUPERFAMILY SSF101386 6 107 4.49E-24 T 29-03-2018 HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 SUPERFAMILY SSF101386 138 238 2.43E-25 T 29-03-2018 HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 TIGRFAM TIGR00444 mazG: MazG family protein 14 258 4.0E-93 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 Gene3D G3DSA:1.10.287.1080 140 260 2.8E-27 T 29-03-2018 HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 Gene3D G3DSA:1.10.287.1080 7 125 5.2E-41 T 29-03-2018 HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 1.2E-26 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HVS_RS00555 f4ea907be13710783c1badacf2d64585 260 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 168 227 8.0E-8 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HVS_RS07630 bf277c691c54b505524afc4fbb082440 67 SUPERFAMILY SSF54862 3 66 8.65E-15 T 29-03-2018 HVS_RS07630 bf277c691c54b505524afc4fbb082440 67 Gene3D G3DSA:3.30.70.20 1 18 2.4E-6 T 29-03-2018 HVS_RS07630 bf277c691c54b505524afc4fbb082440 67 Pfam PF12838 4Fe-4S dicluster domain 10 59 1.4E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS07630 bf277c691c54b505524afc4fbb082440 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS07630 bf277c691c54b505524afc4fbb082440 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 48 59 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS07630 bf277c691c54b505524afc4fbb082440 67 Gene3D G3DSA:3.30.70.20 19 67 2.2E-10 T 29-03-2018 HVS_RS10120 966482218360b8fdd5fe06fdd6cabfb8 161 SUPERFAMILY SSF64438 4 159 1.01E-46 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic HVS_RS10120 966482218360b8fdd5fe06fdd6cabfb8 161 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 157 26.348 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HVS_RS10120 966482218360b8fdd5fe06fdd6cabfb8 161 Pfam PF03975 CheD chemotactic sensory transduction 48 153 6.1E-36 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 HVS_RS11020 a6493f4943463fb5a0754fa6ba7d5ed0 405 Gene3D G3DSA:3.40.50.2000 1 202 1.9E-21 T 29-03-2018 HVS_RS11020 a6493f4943463fb5a0754fa6ba7d5ed0 405 Gene3D G3DSA:3.40.50.2000 203 370 6.5E-48 T 29-03-2018 HVS_RS11020 a6493f4943463fb5a0754fa6ba7d5ed0 405 Pfam PF00534 Glycosyl transferases group 1 200 364 1.5E-44 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS11020 a6493f4943463fb5a0754fa6ba7d5ed0 405 SUPERFAMILY SSF53756 1 389 1.22E-101 T 29-03-2018 HVS_RS11020 a6493f4943463fb5a0754fa6ba7d5ed0 405 Pfam PF13439 Glycosyltransferase Family 4 15 190 1.9E-35 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS06365 aa302857f62599408b4c88e99594c5dd 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 22 250 40.784 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HVS_RS06365 aa302857f62599408b4c88e99594c5dd 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 29 249 3.2E-85 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HVS_RS06365 aa302857f62599408b4c88e99594c5dd 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 22 249 1.2E-93 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HVS_RS06365 aa302857f62599408b4c88e99594c5dd 251 SUPERFAMILY SSF64005 19 244 1.44E-90 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HVS_RS06365 aa302857f62599408b4c88e99594c5dd 251 Gene3D G3DSA:3.40.1180.10 8 251 5.6E-98 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 HVS_RS06365 aa302857f62599408b4c88e99594c5dd 251 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 195 212 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 Gene3D G3DSA:4.10.640.10 1 89 2.6E-32 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 16 89 22.272 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 SUPERFAMILY SSF46911 19 88 2.09E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 TIGRFAM TIGR00165 S18: ribosomal protein bS18 22 89 4.0E-34 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 Pfam PF01084 Ribosomal protein S18 35 84 1.1E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 37 89 2.0E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 PRINTS PR00974 Ribosomal protein S18 family signature 76 86 6.2E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 PRINTS PR00974 Ribosomal protein S18 family signature 44 54 6.2E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 PRINTS PR00974 Ribosomal protein S18 family signature 62 76 6.2E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 PRINTS PR00974 Ribosomal protein S18 family signature 54 61 6.2E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01195 c64fadf02519e1e93a6aab8d56fad70c 89 ProSitePatterns PS00057 Ribosomal protein S18 signature. 37 60 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 ProSitePatterns PS00018 EF-hand calcium-binding domain. 676 688 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 Gene3D G3DSA:1.10.1330.10 634 706 2.7E-4 T 29-03-2018 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 SMART SM01067 478 564 1.2E-20 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 Pfam PF00759 Glycosyl hydrolase family 9 31 452 9.4E-126 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 SUPERFAMILY SSF63446 635 704 2.16E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 Pfam PF00942 Cellulose binding domain 481 563 2.3E-12 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 SUPERFAMILY SSF48208 28 460 1.95E-140 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 375 391 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 Gene3D G3DSA:1.50.10.10 30 460 1.7E-120 T 29-03-2018 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 Gene3D G3DSA:2.60.40.710 476 622 3.1E-30 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04145 6edeed3627121885b640200d38f45bd7 706 SUPERFAMILY SSF49384 477 623 2.67E-33 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 SUPERFAMILY SSF51735 1 156 5.92E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 SMART SM01350 167 294 3.1E-5 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 Gene3D G3DSA:1.10.1040.10 169 297 5.4E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 9.8E-43 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 276 1.0E-22 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 4.9E-29 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 4.9E-29 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 4.9E-29 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 4.9E-29 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 Gene3D G3DSA:3.40.50.720 1 168 4.5E-27 T 29-03-2018 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 SUPERFAMILY SSF48179 165 294 5.17E-36 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS15415 40178766a2d8f5d107747f1f4bfec3c9 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 298 3.9E-118 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 254 1.6E-96 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 Gene3D G3DSA:3.90.230.10 1 255 5.8E-77 T 29-03-2018 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 40.41 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 Pfam PF00557 Metallopeptidase family M24 12 246 6.7E-49 T 29-03-2018 IPR000994 Peptidase M24 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 1.5E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 1.5E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 74 87 1.5E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 1.5E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 172 190 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS15030 967a4d2daf6bbe943c1779b01a0c0bbe 256 SUPERFAMILY SSF55920 1 253 1.57E-81 T 29-03-2018 IPR000994 Peptidase M24 HVS_RS15100 8ba309fcba892fb909e35d67441e84a0 67 Gene3D G3DSA:1.10.287.310 1 65 5.3E-30 T 29-03-2018 HVS_RS15100 8ba309fcba892fb909e35d67441e84a0 67 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.349 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15100 8ba309fcba892fb909e35d67441e84a0 67 SUPERFAMILY SSF46561 1 63 1.83E-25 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15100 8ba309fcba892fb909e35d67441e84a0 67 Pfam PF00831 Ribosomal L29 protein 4 60 2.7E-28 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15100 8ba309fcba892fb909e35d67441e84a0 67 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.5E-25 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15100 8ba309fcba892fb909e35d67441e84a0 67 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS05515 83612ffcd371aff5253fe1b370960267 368 Gene3D G3DSA:3.40.50.300 120 360 3.4E-17 T 29-03-2018 HVS_RS05515 83612ffcd371aff5253fe1b370960267 368 Gene3D G3DSA:3.40.50.10850 3 115 8.4E-19 T 29-03-2018 HVS_RS05515 83612ffcd371aff5253fe1b370960267 368 SUPERFAMILY SSF52540 127 342 4.83E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13795 66011632296afd830ed4342501aa93ed 623 Gene3D G3DSA:3.60.21.10 38 291 2.0E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS13795 66011632296afd830ed4342501aa93ed 623 SUPERFAMILY SSF56300 39 289 2.13E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS13795 66011632296afd830ed4342501aa93ed 623 Gene3D G3DSA:3.30.572.10 292 493 8.6E-4 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS13795 66011632296afd830ed4342501aa93ed 623 SUPERFAMILY SSF55831 326 482 2.09E-6 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 HVS_RS13795 66011632296afd830ed4342501aa93ed 623 Pfam PF00149 Calcineurin-like phosphoesterase 39 251 1.4E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SUPERFAMILY SSF55785 31 139 2.62E-12 T 29-03-2018 IPR000014 PAS domain HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SMART SM00065 156 312 0.0058 T 29-03-2018 IPR003018 GAF domain GO:0005515 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Gene3D G3DSA:3.30.565.10 410 572 4.9E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Gene3D G3DSA:3.30.450.20 23 133 7.7E-13 T 29-03-2018 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SMART SM00387 456 572 1.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SUPERFAMILY SSF47384 340 412 3.92E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SUPERFAMILY SSF55781 143 324 3.05E-13 T 29-03-2018 IPR029016 GAF domain-like HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SMART SM00388 344 414 2.5E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Gene3D G3DSA:3.30.450.40 134 330 1.7E-12 T 29-03-2018 IPR029016 GAF domain-like HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Pfam PF13426 PAS domain 32 132 2.5E-8 T 29-03-2018 IPR000014 PAS domain HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 457 570 7.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Gene3D G3DSA:1.10.287.130 331 409 4.5E-11 T 29-03-2018 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 551 4.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 530 4.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 570 4.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 4.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 Pfam PF00512 His Kinase A (phospho-acceptor) domain 345 411 2.0E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 139 1.3E-13 T 29-03-2018 IPR000014 PAS domain HVS_RS07100 a153e9c8482f354ac2f57099d5a20deb 572 SUPERFAMILY SSF55874 400 571 1.57E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09955 6a773df12c79cccadaeae75597348e14 252 SUPERFAMILY SSF52096 39 231 6.13E-37 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS09955 6a773df12c79cccadaeae75597348e14 252 Gene3D G3DSA:3.90.226.10 26 240 9.8E-24 T 29-03-2018 HVS_RS09955 6a773df12c79cccadaeae75597348e14 252 Pfam PF00574 Clp protease 45 221 2.1E-29 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 Gene3D G3DSA:1.25.40.10 285 367 2.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 Gene3D G3DSA:1.25.40.10 8 147 1.1E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 Pfam PF13174 Tetratricopeptide repeat 330 360 1.6E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 SUPERFAMILY SSF48452 28 106 2.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 SUPERFAMILY SSF48452 297 363 2.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 SMART SM00028 327 360 1.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 SMART SM00028 32 65 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS11295 e70e026a926a3d2dcd3e80b46e82b358 377 SMART SM00028 66 99 1.1 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 Pfam PF00437 Type II/IV secretion system protein 416 680 4.9E-85 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 SUPERFAMILY SSF160246 219 357 1.29E-38 T 29-03-2018 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 255 360 2.6E-21 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 42 148 1.8E-20 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 SUPERFAMILY SSF52540 392 785 8.3E-104 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 SMART SM00382 541 662 6.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 608 622 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 Gene3D G3DSA:3.30.450.90 374 513 1.8E-45 T 29-03-2018 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 SUPERFAMILY SSF160246 7 145 6.28E-33 T 29-03-2018 HVS_RS10005 1a2a8f37d06640f68112357e381f3c86 790 Gene3D G3DSA:3.40.50.300 514 790 8.7E-71 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF00562 RNA polymerase Rpb2, domain 6 698 1084 2.4E-174 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:3.90.1800.10 1087 1131 3.9E-12 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF04561 RNA polymerase Rpb2, domain 2 361 433 1.0E-6 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF04561 RNA polymerase Rpb2, domain 2 141 289 1.5E-23 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 211 911 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF04565 RNA polymerase Rpb2, domain 3 492 560 1.2E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1162 12.796 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF04560 RNA polymerase Rpb2, domain 7 1086 1161 1.1E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:2.40.50.100 695 766 1.4E-31 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 SUPERFAMILY SSF64484 392 1172 0.0 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 SUPERFAMILY SSF64484 14 289 0.0 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:3.90.1100.10 626 694 6.4E-15 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:3.90.1100.10 20 245 2.0E-59 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:3.90.1100.10 379 625 1.1E-84 T 29-03-2018 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF04563 RNA polymerase beta subunit 28 478 9.7E-29 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:2.40.270.10 862 1070 2.7E-82 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 ProSitePatterns PS01166 RNA polymerases beta chain signature. 937 949 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Gene3D G3DSA:2.40.270.10 767 861 2.2E-10 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS12955 98f7351c4e767a42a6dd956b10c07d7d 1273 Pfam PF10385 RNA polymerase beta subunit external 1 domain 570 637 1.4E-28 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Pfam PF02779 Transketolase, pyrimidine binding domain 313 474 4.3E-43 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 ProSitePatterns PS00801 Transketolase signature 1. 26 45 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 SUPERFAMILY SSF52518 237 373 6.21E-84 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 SUPERFAMILY SSF52518 2 189 6.21E-84 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 SUPERFAMILY SSF52518 309 496 5.44E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 SMART SM00861 311 476 1.9E-69 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 SUPERFAMILY SSF52922 483 616 5.5E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 ProSitePatterns PS00802 Transketolase signature 2. 417 433 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Gene3D G3DSA:3.40.50.970 1 307 1.5E-82 T 29-03-2018 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Gene3D G3DSA:3.40.50.920 486 622 3.1E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Gene3D G3DSA:3.40.50.970 309 480 1.8E-46 T 29-03-2018 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 3 614 2.0E-253 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 616 45.407 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 1 276 5.2E-125 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS08605 9bc74f13e47d21797ccf4cd10c4e7639 628 Pfam PF02780 Transketolase, C-terminal domain 486 607 3.2E-30 T 29-03-2018 IPR033248 Transketolase, C-terminal domain HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 Pfam PF00849 RNA pseudouridylate synthase 86 242 1.7E-36 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 SUPERFAMILY SSF55120 70 300 1.44E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 Pfam PF01479 S4 domain 14 59 1.1E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 SUPERFAMILY SSF55174 13 99 2.35E-13 T 29-03-2018 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 Gene3D G3DSA:3.10.290.10 3 70 9.1E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 9 300 1.6E-102 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 Gene3D G3DSA:3.30.2350.10 77 302 1.5E-73 T 29-03-2018 HVS_RS09350 6092be2ee9e98bb5ed52ccb40ee11a0d 302 SMART SM00363 13 77 9.3E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 SUPERFAMILY SSF53927 208 514 2.71E-125 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 Gene3D G3DSA:3.40.50.1380 1 192 2.7E-76 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 Gene3D G3DSA:3.40.140.20 216 361 1.7E-55 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 Pfam PF02142 MGS-like domain 14 129 1.0E-28 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 SUPERFAMILY SSF52335 2 193 1.96E-73 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 514 4.3E-219 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 SMART SM00851 14 129 3.3E-61 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 447 1.2E-118 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 Gene3D G3DSA:3.40.140.20 363 504 4.2E-50 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 PIRSF PIRSF000414 1 514 1.2E-219 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 SMART SM00798 134 453 1.6E-188 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS06240 d69cdb3917d00dda81be14efe63c2083 514 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 514 44.789 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Pfam PF08529 NusA N-terminal domain 4 123 1.7E-42 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SMART SM00322 303 359 4.0 T 29-03-2018 IPR004087 K Homology domain GO:0003676 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SMART SM00322 229 302 8.5E-4 T 29-03-2018 IPR004087 K Homology domain GO:0003676 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Gene3D G3DSA:2.40.50.140 135 197 4.0E-15 T 29-03-2018 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 342 1.3E-132 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SUPERFAMILY SSF54814 199 276 4.19E-32 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Gene3D G3DSA:3.30.1480.10 1 129 1.9E-47 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Pfam PF13184 NusA-like KH domain 229 296 1.4E-30 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SUPERFAMILY SSF50249 132 198 1.46E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 377 31.183 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Pfam PF00575 S1 RNA binding domain 133 194 1.1E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SUPERFAMILY SSF54814 278 341 6.47E-15 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SUPERFAMILY SSF69705 1 126 1.57E-41 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 SMART SM00316 133 199 3.7E-8 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Gene3D G3DSA:3.30.300.20 198 272 2.9E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS10535 6a7e9c5b670ae99dab7e36a336814d6c 424 Gene3D G3DSA:3.30.300.20 273 341 9.9E-18 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS13595 dbdd001b7ad8f98f7947a096c2a6cfff 598 Pfam PF03235 Protein of unknown function DUF262 23 218 1.8E-31 T 29-03-2018 IPR004919 Domain of unknown function DUF262 HVS_RS11670 c92206a5f4b8abd1d6a5eb327a9554a3 208 Gene3D G3DSA:1.10.3470.10 95 206 4.8E-4 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like HVS_RS12765 ef6b8ffc93f784ed7c49fb7939847e1e 313 Pfam PF13732 Domain of unknown function (DUF4162) 223 306 1.0E-17 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 HVS_RS12765 ef6b8ffc93f784ed7c49fb7939847e1e 313 SUPERFAMILY SSF52540 2 238 2.5E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12765 ef6b8ffc93f784ed7c49fb7939847e1e 313 SMART SM00382 27 217 3.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12765 ef6b8ffc93f784ed7c49fb7939847e1e 313 Gene3D G3DSA:3.40.50.300 1 300 1.7E-53 T 29-03-2018 HVS_RS12765 ef6b8ffc93f784ed7c49fb7939847e1e 313 Pfam PF00005 ABC transporter 18 169 5.4E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS04865 2b174f888fe7120035ae740c24d09411 165 Gene3D G3DSA:3.30.565.10 18 165 2.1E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS04865 2b174f888fe7120035ae740c24d09411 165 SUPERFAMILY SSF55874 38 162 9.95E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS04865 2b174f888fe7120035ae740c24d09411 165 SMART SM00387 52 164 0.0011 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS04865 2b174f888fe7120035ae740c24d09411 165 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 52 162 3.6E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS13195 d8868633a547d97ab8c1172d808d778f 400 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 9 396 5.7E-119 T 29-03-2018 IPR024455 Phage capsid HVS_RS13195 d8868633a547d97ab8c1172d808d778f 400 SUPERFAMILY SSF56563 117 397 1.26E-88 T 29-03-2018 HVS_RS13195 d8868633a547d97ab8c1172d808d778f 400 Pfam PF05065 Phage capsid family 124 396 1.8E-89 T 29-03-2018 IPR024455 Phage capsid HVS_RS13195 d8868633a547d97ab8c1172d808d778f 400 Gene3D G3DSA:3.30.2400.10 145 289 1.3E-41 T 29-03-2018 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 SMART SM00825 Beta-ketoacyl synthase 5 412 4.9E-19 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 Gene3D G3DSA:3.40.47.10 261 412 8.7E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.9E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 Gene3D G3DSA:3.40.47.10 5 258 2.5E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 PIRSF PIRSF000447 1 412 6.1E-187 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 8.2E-199 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 SUPERFAMILY SSF53901 213 410 4.5E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 SUPERFAMILY SSF53901 3 250 4.46E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08810 26d0c463e13a0cfd39e27a57cc71d081 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 367 2.6E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal HVS_RS07110 6fd83811ab1a9f75560e56a85cd8030d 96 SUPERFAMILY SSF103007 1 94 1.96E-30 T 29-03-2018 IPR007546 Protein of unknown function DUF503 HVS_RS07110 6fd83811ab1a9f75560e56a85cd8030d 96 Pfam PF04456 Protein of unknown function (DUF503) 3 89 8.3E-33 T 29-03-2018 IPR007546 Protein of unknown function DUF503 HVS_RS07110 6fd83811ab1a9f75560e56a85cd8030d 96 Gene3D G3DSA:3.30.70.1120 2 92 1.2E-32 T 29-03-2018 HVS_RS04175 1943db92f8a6bfa908fe5cee8eecd1fa 347 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 281 9.0E-7 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS04175 1943db92f8a6bfa908fe5cee8eecd1fa 347 Gene3D G3DSA:3.90.550.10 1 241 8.3E-69 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS04175 1943db92f8a6bfa908fe5cee8eecd1fa 347 SUPERFAMILY SSF53448 1 235 3.52E-81 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS04175 1943db92f8a6bfa908fe5cee8eecd1fa 347 Gene3D G3DSA:2.160.10.10 242 343 2.4E-21 T 29-03-2018 HVS_RS04175 1943db92f8a6bfa908fe5cee8eecd1fa 347 SUPERFAMILY SSF51161 198 331 1.44E-21 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS04175 1943db92f8a6bfa908fe5cee8eecd1fa 347 Pfam PF00483 Nucleotidyl transferase 2 232 2.7E-53 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS04205 857aa5e1f01c1c708b4e9dd166dad215 749 Gene3D G3DSA:3.40.50.300 205 562 2.7E-31 T 29-03-2018 HVS_RS04205 857aa5e1f01c1c708b4e9dd166dad215 749 Pfam PF00580 UvrD/REP helicase N-terminal domain 208 555 3.0E-11 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HVS_RS04205 857aa5e1f01c1c708b4e9dd166dad215 749 Gene3D G3DSA:3.40.50.300 578 749 1.0E-25 T 29-03-2018 HVS_RS04205 857aa5e1f01c1c708b4e9dd166dad215 749 Pfam PF13538 UvrD-like helicase C-terminal domain 685 727 7.4E-8 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain HVS_RS04205 857aa5e1f01c1c708b4e9dd166dad215 749 SUPERFAMILY SSF52540 199 354 5.77E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04205 857aa5e1f01c1c708b4e9dd166dad215 749 SUPERFAMILY SSF52540 491 733 5.77E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 Pfam PF01476 LysM domain 39 82 1.7E-18 T 29-03-2018 IPR018392 LysM domain HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 Pfam PF01476 LysM domain 96 139 6.8E-16 T 29-03-2018 IPR018392 LysM domain HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 Gene3D G3DSA:3.10.350.10 89 141 2.4E-19 T 29-03-2018 HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 Gene3D G3DSA:3.10.350.10 36 84 5.9E-20 T 29-03-2018 HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 SMART SM00257 95 139 7.3E-17 T 29-03-2018 IPR018392 LysM domain HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 SMART SM00257 38 82 1.5E-17 T 29-03-2018 IPR018392 LysM domain HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 SUPERFAMILY SSF54106 37 82 2.35E-14 T 29-03-2018 IPR018392 LysM domain HVS_RS00605 1e4b1b1720fb0de1619835d1466feecf 141 SUPERFAMILY SSF54106 94 139 3.27E-13 T 29-03-2018 IPR018392 LysM domain HVS_RS04840 1b8eff94e29d414c4cfe5dc52ea8c688 393 SUPERFAMILY SSF63829 320 382 5.01E-8 T 29-03-2018 HVS_RS04840 1b8eff94e29d414c4cfe5dc52ea8c688 393 Gene3D G3DSA:2.120.10.30 121 383 9.3E-7 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like HVS_RS04840 1b8eff94e29d414c4cfe5dc52ea8c688 393 Pfam PF00395 S-layer homology domain 174 217 3.9E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS04840 1b8eff94e29d414c4cfe5dc52ea8c688 393 Pfam PF00395 S-layer homology domain 112 155 1.4E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS04840 1b8eff94e29d414c4cfe5dc52ea8c688 393 Pfam PF00395 S-layer homology domain 53 94 5.2E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Gene3D G3DSA:1.10.101.10 179 255 9.1E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Gene3D G3DSA:1.10.101.10 276 351 1.4E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Pfam PF01471 Putative peptidoglycan binding domain 190 246 1.4E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Pfam PF01471 Putative peptidoglycan binding domain 286 342 1.3E-5 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Gene3D G3DSA:1.20.1170.10 2 153 1.1E-5 T 29-03-2018 HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 SMART SM00047 458 606 1.8E-23 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 SUPERFAMILY SSF47090 178 248 6.02E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 471 602 7.4E-14 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Gene3D G3DSA:1.10.530.10 455 605 8.0E-24 T 29-03-2018 HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 SUPERFAMILY SSF54106 647 693 2.09E-12 T 29-03-2018 IPR018392 LysM domain HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 SMART SM00257 648 692 1.3E-16 T 29-03-2018 IPR018392 LysM domain HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Pfam PF01476 LysM domain 649 692 1.4E-14 T 29-03-2018 IPR018392 LysM domain HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 Gene3D G3DSA:3.10.350.10 641 707 2.7E-17 T 29-03-2018 HVS_RS03415 673afbb2f1161ab9cd37ff97ddcdd0d2 731 SUPERFAMILY SSF47090 283 344 1.83E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF56784 453 472 1.37E-59 T 29-03-2018 IPR023214 HAD-like domain HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF56784 511 753 1.37E-59 T 29-03-2018 IPR023214 HAD-like domain HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Gene3D G3DSA:3.30.70.100 19 91 3.8E-23 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 173 755 1.1E-190 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Gene3D G3DSA:3.40.50.1000 579 716 7.1E-43 T 29-03-2018 IPR023214 HAD-like domain HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 ProSitePatterns PS01047 Heavy-metal-associated domain. 26 55 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Gene3D G3DSA:1.20.1110.10 193 469 1.5E-43 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Gene3D G3DSA:3.40.1110.10 470 578 5.3E-33 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Pfam PF00122 E1-E2 ATPase 236 433 1.2E-51 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF81665 702 716 4.05E-9 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF81665 334 448 4.05E-9 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF81665 203 237 4.05E-9 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF55008 17 90 1.44E-21 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 SUPERFAMILY SSF81653 238 333 1.7E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 456 462 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00941 Cadmium-transporting ATPase signature 218 238 1.1E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00941 Cadmium-transporting ATPase signature 35 56 1.1E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00941 Cadmium-transporting ATPase signature 24 33 1.1E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00941 Cadmium-transporting ATPase signature 299 315 1.1E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00941 Cadmium-transporting ATPase signature 318 332 1.1E-11 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 206 742 7.9E-88 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Pfam PF00403 Heavy-metal-associated domain 23 84 1.5E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 Pfam PF00702 haloacid dehalogenase-like hydrolase 450 666 2.9E-46 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 283 297 5.0E-30 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 672 5.0E-30 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 578 589 5.0E-30 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 688 5.0E-30 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 610 5.0E-30 T 29-03-2018 HVS_RS13880 5534eca793019718cd1da619259dcbb0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 454 468 5.0E-30 T 29-03-2018 HVS_RS02475 cca0c62508da1c91dffd6fefdfa7c1a2 470 SUPERFAMILY SSF56601 96 466 2.41E-87 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS02475 cca0c62508da1c91dffd6fefdfa7c1a2 470 Gene3D G3DSA:3.90.1310.10 50 134 5.0E-17 T 29-03-2018 HVS_RS02475 cca0c62508da1c91dffd6fefdfa7c1a2 470 Pfam PF00905 Penicillin binding protein transpeptidase domain 152 460 4.7E-64 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HVS_RS02475 cca0c62508da1c91dffd6fefdfa7c1a2 470 Gene3D G3DSA:3.40.710.10 135 470 9.3E-91 T 29-03-2018 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 Gene3D G3DSA:3.30.565.10 152 298 6.4E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 SMART SM00387 193 300 1.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 194 284 4.6E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 SUPERFAMILY SSF55874 154 284 1.44E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 SMART SM00388 81 147 9.5E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 Gene3D G3DSA:1.10.287.130 70 142 1.3E-15 T 29-03-2018 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 SUPERFAMILY SSF47384 68 145 3.53E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 Pfam PF00512 His Kinase A (phospho-acceptor) domain 82 146 3.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 PRINTS PR01780 Lantibiotic regulatory protein signature 189 204 3.3E-6 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 PRINTS PR01780 Lantibiotic regulatory protein signature 90 106 3.3E-6 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 HVS_RS03085 4016315a4dfd69c88b38b5f5efed69dd 300 PRINTS PR01780 Lantibiotic regulatory protein signature 251 266 3.3E-6 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 HVS_RS03670 96305f9ced82fd52e098e9c4ffaa7c7d 141 SUPERFAMILY SSF50249 1 141 7.2E-46 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS03670 96305f9ced82fd52e098e9c4ffaa7c7d 141 Hamap MF_00984 Single-stranded DNA-binding protein. 1 106 30.299 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HVS_RS03670 96305f9ced82fd52e098e9c4ffaa7c7d 141 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 119 6.2E-33 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HVS_RS03670 96305f9ced82fd52e098e9c4ffaa7c7d 141 Pfam PF00436 Single-strand binding protein family 1 101 8.5E-35 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HVS_RS03670 96305f9ced82fd52e098e9c4ffaa7c7d 141 PIRSF PIRSF002070 1 137 3.4E-37 T 29-03-2018 HVS_RS03670 96305f9ced82fd52e098e9c4ffaa7c7d 141 Gene3D G3DSA:2.40.50.140 1 110 5.3E-39 T 29-03-2018 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Gene3D G3DSA:2.60.40.1190 1018 1202 8.9E-40 T 29-03-2018 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Gene3D G3DSA:2.60.120.260 38 197 5.6E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF00395 S-layer homology domain 1424 1465 9.1E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF00395 S-layer homology domain 1482 1525 1.4E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF00395 S-layer homology domain 1548 1591 1.1E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SUPERFAMILY SSF49785 357 504 1.15E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SUPERFAMILY SSF51445 666 1001 3.01E-85 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SUPERFAMILY SSF49344 1018 1201 1.49E-49 T 29-03-2018 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Gene3D G3DSA:2.60.120.260 508 653 1.0E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Gene3D G3DSA:2.60.120.260 355 503 1.6E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF02018 Carbohydrate binding domain 38 157 5.1E-10 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF02018 Carbohydrate binding domain 358 490 2.2E-20 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF02018 Carbohydrate binding domain 510 635 9.7E-17 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF02018 Carbohydrate binding domain 197 309 4.1E-8 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SUPERFAMILY SSF49785 506 653 1.57E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Gene3D G3DSA:3.20.20.80 659 1016 1.3E-63 T 29-03-2018 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SMART SM00633 711 1002 6.6E-78 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF00331 Glycosyl hydrolase family 10 671 1000 8.6E-97 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Gene3D G3DSA:2.60.120.260 198 348 3.2E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 Pfam PF06452 Carbohydrate family 9 binding domain-like 1027 1202 1.5E-58 T 29-03-2018 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 PRINTS PR00134 Glycosyl hydrolase family 10 signature 790 801 1.4E-7 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 PRINTS PR00134 Glycosyl hydrolase family 10 signature 742 754 1.4E-7 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 PRINTS PR00134 Glycosyl hydrolase family 10 signature 850 861 1.4E-7 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SUPERFAMILY SSF49785 192 345 1.19E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 918 928 - T 29-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 ProDom PD004647 DEGRADATION HYDROLASE GLYCOSIDASE XYLAN A XYLANASE PRECURSOR SIGNAL REPEAT 14- 1024 1201 5.0E-61 T 29-03-2018 HVS_RS12825 f22978ae807721bee80aedbc06143560 1601 SUPERFAMILY SSF49785 38 189 2.98E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS11880 488a4e70289956396a5c89ae57a1bbcb 326 Gene3D G3DSA:3.90.550.10 2 196 1.5E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS11880 488a4e70289956396a5c89ae57a1bbcb 326 Pfam PF00535 Glycosyl transferase family 2 8 170 9.9E-40 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HVS_RS11880 488a4e70289956396a5c89ae57a1bbcb 326 SUPERFAMILY SSF53448 4 261 1.88E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 SUPERFAMILY SSF56519 187 312 1.09E-41 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 SUPERFAMILY SSF56519 45 109 1.09E-41 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 Gene3D G3DSA:3.90.1310.10 21 312 1.1E-47 T 29-03-2018 HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 Pfam PF00905 Penicillin binding protein transpeptidase domain 350 681 5.6E-68 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 Gene3D G3DSA:3.40.710.10 313 692 1.9E-97 T 29-03-2018 HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 Pfam PF03717 Penicillin-binding Protein dimerisation domain 53 298 1.4E-47 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 SUPERFAMILY SSF56601 313 686 3.35E-87 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS05390 8f8af1050fbc63f8dd34120fcdf0c731 706 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 188 686 4.0E-145 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 HVS_RS10270 7047df6ed8903458e6a56e4dad5cda35 144 Pfam PF00460 Flagella basal body rod protein 7 34 1.7E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HVS_RS10270 7047df6ed8903458e6a56e4dad5cda35 144 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 92 141 5.5E-14 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HVS_RS10270 7047df6ed8903458e6a56e4dad5cda35 144 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 144 3.1E-57 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 Gene3D G3DSA:3.30.700.20 287 398 1.7E-34 T 29-03-2018 IPR027485 AMMECR1, N-terminal HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 SUPERFAMILY SSF53213 2 276 1.23E-44 T 29-03-2018 HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 290 454 1.3E-26 T 29-03-2018 IPR023473 AMMECR1 HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 268 9.2E-41 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 290 452 3.8E-38 T 29-03-2018 IPR027623 AmmeMemoRadiSam system protein A HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 Pfam PF01871 AMMECR1 292 454 6.2E-40 T 29-03-2018 IPR002733 AMMECR1 domain HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 SUPERFAMILY SSF143447 283 456 1.7E-47 T 29-03-2018 IPR002733 AMMECR1 domain HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 Gene3D G3DSA:3.30.1490.150 399 454 1.8E-6 T 29-03-2018 HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 Gene3D G3DSA:3.40.830.10 1 286 9.4E-56 T 29-03-2018 HVS_RS06470 eaff5150097ef05aea1da96efd033b26 456 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 132 256 3.0E-10 T 29-03-2018 HVS_RS15635 9766f4ad2cf3deb4c4edf7fb4a8f0b67 269 SUPERFAMILY SSF56752 18 252 9.03E-51 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 HVS_RS15635 9766f4ad2cf3deb4c4edf7fb4a8f0b67 269 Pfam PF01063 Amino-transferase class IV 41 240 4.4E-40 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 HVS_RS15635 9766f4ad2cf3deb4c4edf7fb4a8f0b67 269 ProSitePatterns PS00770 Aminotransferases class-IV signature. 173 202 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 HVS_RS15635 9766f4ad2cf3deb4c4edf7fb4a8f0b67 269 Gene3D G3DSA:3.30.470.10 14 113 2.6E-10 T 29-03-2018 HVS_RS15635 9766f4ad2cf3deb4c4edf7fb4a8f0b67 269 Gene3D G3DSA:3.20.10.10 114 258 1.0E-32 T 29-03-2018 HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 SUPERFAMILY SSF160240 203 281 1.96E-20 T 29-03-2018 HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 2 281 5.6E-72 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 SUPERFAMILY SSF161111 2 201 1.83E-54 T 29-03-2018 HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 Pfam PF16916 Dimerisation domain of Zinc Transporter 204 281 2.6E-24 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 Pfam PF01545 Cation efflux family 6 200 2.0E-52 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 Gene3D G3DSA:1.20.1510.10 2 199 7.5E-47 T 29-03-2018 HVS_RS08475 9799f4adb7939191ff4b4e8356a28fa0 282 Gene3D G3DSA:3.30.70.1350 200 282 9.6E-22 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain HVS_RS08400 be3cd1370dd05bf90a89f561041236ef 94 Gene3D G3DSA:3.10.350.10 42 94 2.8E-10 T 29-03-2018 HVS_RS08400 be3cd1370dd05bf90a89f561041236ef 94 Pfam PF01476 LysM domain 45 91 2.5E-9 T 29-03-2018 IPR018392 LysM domain HVS_RS08400 be3cd1370dd05bf90a89f561041236ef 94 SMART SM00257 43 92 6.5E-5 T 29-03-2018 IPR018392 LysM domain HVS_RS08400 be3cd1370dd05bf90a89f561041236ef 94 SUPERFAMILY SSF54106 40 92 1.96E-6 T 29-03-2018 IPR018392 LysM domain HVS_RS15345 ed6afc78513ec6f573763fc0390d9780 432 Pfam PF14319 Transposase zinc-binding domain 15 121 3.5E-24 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS15345 ed6afc78513ec6f573763fc0390d9780 432 Pfam PF04986 Putative transposase 153 321 4.1E-39 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 124 130 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 Gene3D G3DSA:1.10.10.10 70 156 4.5E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 75 154 1.1E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 154 37.859 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 SUPERFAMILY SSF53155 9 79 2.47E-14 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 74 153 7.3E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 SUPERFAMILY SSF46767 73 154 3.66E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 HVS_RS04110 5c2928cccdefa2755e5fd1ca07c71d9f 160 Gene3D G3DSA:3.30.160.70 7 69 2.1E-12 T 29-03-2018 HVS_RS06995 aa8b7f1b0468be63762d56c1de18fa40 258 SUPERFAMILY SSF88713 21 238 4.0E-63 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HVS_RS06995 aa8b7f1b0468be63762d56c1de18fa40 258 Gene3D G3DSA:3.20.20.370 31 249 2.0E-55 T 29-03-2018 HVS_RS06995 aa8b7f1b0468be63762d56c1de18fa40 258 Pfam PF01522 Polysaccharide deacetylase 53 170 1.5E-35 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HVS_RS06490 bf39ad4733588b492d2dae3e0688e0d6 530 Gene3D G3DSA:3.50.50.60 92 524 7.1E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS06490 bf39ad4733588b492d2dae3e0688e0d6 530 PIRSF PIRSF038984 1 529 1.5E-225 T 29-03-2018 IPR028348 FAD dependent protein HVS_RS06490 bf39ad4733588b492d2dae3e0688e0d6 530 SUPERFAMILY SSF51905 463 523 2.0E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS06490 bf39ad4733588b492d2dae3e0688e0d6 530 SUPERFAMILY SSF51905 97 290 2.0E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS06490 bf39ad4733588b492d2dae3e0688e0d6 530 PRINTS PR00419 Adrenodoxin reductase family signature 95 117 2.4E-5 T 29-03-2018 HVS_RS06490 bf39ad4733588b492d2dae3e0688e0d6 530 PRINTS PR00419 Adrenodoxin reductase family signature 252 266 2.4E-5 T 29-03-2018 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Gene3D G3DSA:3.90.190.20 320 465 5.0E-37 T 29-03-2018 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Pfam PF01225 Mur ligase family, catalytic domain 14 112 1.7E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Gene3D G3DSA:3.40.50.720 3 100 2.1E-14 T 29-03-2018 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 SUPERFAMILY SSF53244 318 459 2.93E-44 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 12 465 39.025 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 SUPERFAMILY SSF53623 102 316 8.24E-62 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Pfam PF02875 Mur ligase family, glutamate ligase domain 320 401 1.2E-22 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 SUPERFAMILY SSF51984 13 99 1.31E-28 T 29-03-2018 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Pfam PF08245 Mur ligase middle domain 118 298 2.3E-33 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 Gene3D G3DSA:3.40.1190.10 101 319 1.3E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS00515 1abf02ea2b192439420acdf354920374 469 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 14 459 1.5E-152 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 50 375 6.2E-47 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 Gene3D G3DSA:3.40.50.1100 194 392 1.4E-41 T 29-03-2018 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 4 387 1.9E-198 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 SUPERFAMILY SSF53686 3 385 2.75E-147 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 PIRSF PIRSF001413 2 394 1.4E-174 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 388 52.802 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 Gene3D G3DSA:3.40.50.1100 6 65 2.4E-9 T 29-03-2018 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 Gene3D G3DSA:3.40.50.1100 66 193 3.1E-39 T 29-03-2018 HVS_RS02350 f352a6c53416d04b4648d4536fb75bbd 394 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 78 92 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 Gene3D G3DSA:3.60.20.10 30 310 5.5E-73 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 PIRSF PIRSF000485 26 488 2.2E-172 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 SUPERFAMILY SSF56235 30 259 7.12E-65 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 SUPERFAMILY SSF53271 269 482 1.21E-68 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 30 475 5.8E-161 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 29 474 46.333 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 Gene3D G3DSA:3.40.50.2020 311 441 5.8E-20 T 29-03-2018 HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 Pfam PF13537 Glutamine amidotransferase domain 109 232 4.0E-22 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain HVS_RS06225 37742dd4c0bf2467f06fac47e83f28bd 488 Pfam PF00156 Phosphoribosyl transferase domain 297 404 2.7E-6 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 SUPERFAMILY SSF49384 500 656 9.42E-32 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 446 464 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 SMART SM01067 501 584 1.4E-13 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 Gene3D G3DSA:1.50.10.10 49 477 3.0E-120 T 29-03-2018 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 Pfam PF00404 Dockerin type I repeat 709 729 2.3E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 SUPERFAMILY SSF48208 49 478 1.43E-140 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 Pfam PF00759 Glycosyl hydrolase family 9 51 470 6.1E-127 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 SUPERFAMILY SSF63446 672 737 3.01E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 709 728 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 Gene3D G3DSA:2.60.40.710 499 655 1.8E-26 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS08125 595d90d3378b0a2a0cc158f10c35f1fc 738 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 396 412 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS11560 bc321142b11b102c67a1f2f059a74273 109 Gene3D G3DSA:3.30.70.1490 2 108 7.1E-29 T 29-03-2018 IPR007422 Cysteine protease Prp HVS_RS11560 bc321142b11b102c67a1f2f059a74273 109 SUPERFAMILY SSF118010 1 107 1.07E-28 T 29-03-2018 IPR007422 Cysteine protease Prp HVS_RS11560 bc321142b11b102c67a1f2f059a74273 109 Pfam PF04327 Cysteine protease Prp 1 102 5.5E-24 T 29-03-2018 IPR007422 Cysteine protease Prp HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 4.3E-23 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 7.4E-80 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Gene3D G3DSA:1.10.260.30 327 430 1.6E-40 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 SUPERFAMILY SSF52540 43 354 8.63E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 SMART SM00382 100 301 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 448 35.446 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Gene3D G3DSA:3.40.50.300 96 234 1.1E-39 T 29-03-2018 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Gene3D G3DSA:1.20.120.140 1 92 5.8E-30 T 29-03-2018 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 SMART SM00962 101 296 2.2E-122 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Gene3D G3DSA:3.40.50.300 235 317 0.0013 T 29-03-2018 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 Pfam PF02978 Signal peptide binding domain 327 424 5.8E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 426 1.3E-193 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 SUPERFAMILY SSF47446 327 428 1.19E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 HVS_RS08380 0c2d1f096a24064847f651e4af4b70b0 449 SMART SM00963 2 87 2.4E-35 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS09640 6ba0bf6e48fc0b5994259e6710f33d53 233 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 10 232 8.0E-63 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein HVS_RS09640 6ba0bf6e48fc0b5994259e6710f33d53 233 SUPERFAMILY SSF51419 7 230 2.49E-76 T 29-03-2018 IPR029066 PLP-binding barrel HVS_RS09640 6ba0bf6e48fc0b5994259e6710f33d53 233 Gene3D G3DSA:3.20.20.10 2 233 3.8E-61 T 29-03-2018 IPR029066 PLP-binding barrel HVS_RS09640 6ba0bf6e48fc0b5994259e6710f33d53 233 PIRSF PIRSF004848 3 233 5.1E-77 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein HVS_RS09640 6ba0bf6e48fc0b5994259e6710f33d53 233 Pfam PF01168 Alanine racemase, N-terminal domain 32 232 1.7E-20 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 SUPERFAMILY SSF50156 192 282 9.6E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 Pfam PF02163 Peptidase family M50 6 422 1.5E-62 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 Pfam PF13180 PDZ domain 201 276 3.2E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 Gene3D G3DSA:2.30.42.10 197 289 2.0E-14 T 29-03-2018 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 SMART SM00228 199 268 4.7E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 SMART SM00228 102 174 9.3E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 SUPERFAMILY SSF50156 90 173 3.29E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 Gene3D G3DSA:2.30.42.10 104 191 1.2E-11 T 29-03-2018 HVS_RS06380 a71eee06396855f73717a2d1284f3723 437 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 435 4.3E-78 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 HVS_RS07925 81ee77cab90ea9574ac8db592f426324 373 Pfam PF11202 Phosphoribosyl transferase (PRTase) 17 265 2.7E-109 T 29-03-2018 IPR011215 Phosphoribosyl transferase HVS_RS07925 81ee77cab90ea9574ac8db592f426324 373 PIRSF PIRSF020979 8 371 9.8E-87 T 29-03-2018 IPR011215 Phosphoribosyl transferase HVS_RS07925 81ee77cab90ea9574ac8db592f426324 373 Pfam PF15608 PELOTA RNA binding domain 293 372 2.6E-34 T 29-03-2018 IPR028157 PELOTA RNA-binding domain HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 Gene3D G3DSA:3.50.50.60 334 419 8.7E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 Pfam PF00890 FAD binding domain 11 375 7.6E-25 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 Gene3D G3DSA:3.50.50.60 5 244 1.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 Gene3D G3DSA:3.90.700.10 245 333 7.0E-34 T 29-03-2018 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 Gene3D G3DSA:1.20.58.100 420 525 1.4E-19 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 PIRSF PIRSF000171 1 562 1.6E-206 T 29-03-2018 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 SUPERFAMILY SSF56425 231 350 2.82E-28 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 Pfam PF02910 Fumarate reductase flavoprotein C-term 438 550 3.3E-5 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 SUPERFAMILY SSF51905 6 248 5.9E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 SUPERFAMILY SSF51905 352 403 5.9E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 SUPERFAMILY SSF46977 428 550 2.62E-26 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 4.5E-8 T 29-03-2018 HVS_RS02675 fa10e25d02d357899e0bf2b056db27f2 562 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.5E-8 T 29-03-2018 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 2.1E-177 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 367 3.1E-34 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 44.519 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 254 1.3E-20 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 SUPERFAMILY SSF53738 3 181 2.43E-48 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Gene3D G3DSA:3.40.120.10 264 374 4.8E-34 T 29-03-2018 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 SUPERFAMILY SSF53738 258 365 5.1E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 2.2E-11 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 2.2E-11 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 2.2E-11 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 SUPERFAMILY SSF53738 157 257 2.43E-30 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 SUPERFAMILY SSF55957 358 449 1.44E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 1.0E-43 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Gene3D G3DSA:3.40.120.10 167 263 7.4E-31 T 29-03-2018 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Gene3D G3DSA:3.40.120.10 2 166 5.2E-46 T 29-03-2018 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 445 6.1E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS06495 5a529e000e9c560da83ba14dc31ca5e2 449 Gene3D G3DSA:3.30.310.50 375 449 1.5E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 SUPERFAMILY SSF55681 242 523 9.77E-99 T 29-03-2018 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 SMART SM00863 169 218 4.3E-23 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Pfam PF03129 Anticodon binding domain 539 628 2.9E-27 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 SUPERFAMILY SSF52954 527 632 1.19E-35 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 SUPERFAMILY SSF81271 2 62 7.41E-15 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 SUPERFAMILY SSF55186 64 240 4.45E-68 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 527 1.2E-38 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 PRINTS PR01047 Threonyl-tRNA synthetase signature 462 490 3.4E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 PRINTS PR01047 Threonyl-tRNA synthetase signature 532 544 3.4E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 518 3.4E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 3.4E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 3.4E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Gene3D G3DSA:3.40.50.800 530 632 1.2E-31 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 2.7E-234 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Pfam PF02824 TGS domain 2 61 5.4E-12 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 632 35.632 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Gene3D G3DSA:3.30.980.10 65 142 8.3E-26 T 29-03-2018 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Gene3D G3DSA:3.30.930.10 220 529 1.8E-125 T 29-03-2018 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Gene3D G3DSA:3.30.54.20 143 186 1.3E-22 T 29-03-2018 HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Gene3D G3DSA:3.10.20.30 1 63 3.5E-19 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS10585 83ab14b3659554f7df0639e06c9a7308 634 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.3E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HVS_RS03265 98f082eb1994a0fde7abad98fe6a6f94 251 Gene3D G3DSA:3.40.50.300 1 238 4.4E-54 T 29-03-2018 HVS_RS03265 98f082eb1994a0fde7abad98fe6a6f94 251 SMART SM00382 26 223 2.6E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS03265 98f082eb1994a0fde7abad98fe6a6f94 251 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS03265 98f082eb1994a0fde7abad98fe6a6f94 251 SUPERFAMILY SSF52540 2 231 6.3E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03265 98f082eb1994a0fde7abad98fe6a6f94 251 Pfam PF00005 ABC transporter 17 166 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.3E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.3E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.3E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.3E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.3E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 SUPERFAMILY SSF52374 2 155 1.34E-48 T 29-03-2018 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.182 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 Gene3D G3DSA:3.40.50.620 1 158 3.1E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 81 4.0E-4 T 29-03-2018 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 63 6.7E-21 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 155 9.6E-60 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 HVS_RS10870 fc0a61911b93ac4fc044d6cf7cc6bd3d 160 Pfam PF01467 Cytidylyltransferase-like 5 133 1.8E-25 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HVS_RS10560 aa6a5ec0114286ceb900adf255899eb1 384 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 3 378 3.0E-156 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 SUPERFAMILY SSF50249 13 103 2.24E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 222 235 2.4E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 218 2.4E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 419 433 2.4E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 379 395 2.4E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 464 47.151 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 Pfam PF01336 OB-fold nucleic acid binding domain 22 99 2.1E-13 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 4 464 1.1E-197 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 SUPERFAMILY SSF55681 103 462 1.23E-101 T 29-03-2018 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 Gene3D G3DSA:2.40.50.140 1 108 1.8E-20 T 29-03-2018 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 458 9.2E-89 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS05265 9e5ff068c03f8c75fecc8efd3ee059d8 464 Gene3D G3DSA:3.30.930.10 126 460 1.2E-100 T 29-03-2018 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 SUPERFAMILY SSF52016 438 640 2.94E-54 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Pfam PF00330 Aconitase family (aconitate hydratase) 8 407 3.6E-114 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 SUPERFAMILY SSF53732 1 417 2.22E-152 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Gene3D G3DSA:3.30.499.10 270 440 5.7E-55 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Gene3D G3DSA:3.30.499.10 1 146 4.0E-44 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 640 2.1E-290 T 29-03-2018 IPR006250 Aconitase, putative HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Pfam PF00694 Aconitase C-terminal domain 521 575 1.6E-22 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 PRINTS PR00415 Aconitase family signature 200 213 3.2E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 PRINTS PR00415 Aconitase family signature 349 362 3.2E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 PRINTS PR00415 Aconitase family signature 110 123 3.2E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 PRINTS PR00415 Aconitase family signature 90 98 3.2E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 PRINTS PR00415 Aconitase family signature 186 199 3.2E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 PRINTS PR00415 Aconitase family signature 124 139 3.2E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Gene3D G3DSA:3.20.19.10 457 514 8.6E-13 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Gene3D G3DSA:3.20.19.10 515 642 1.9E-39 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HVS_RS12155 8e361990695e2733370dea92c7d8999b 642 Gene3D G3DSA:3.40.1060.10 147 269 4.0E-43 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS08845 7582c8f091e88360d27d830d08fc31eb 205 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 200 2.1E-51 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 HVS_RS08845 7582c8f091e88360d27d830d08fc31eb 205 PIRSF PIRSF000847 1 205 5.3E-49 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 HVS_RS08845 7582c8f091e88360d27d830d08fc31eb 205 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 93 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HVS_RS08845 7582c8f091e88360d27d830d08fc31eb 205 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 93 9.3E-19 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Gene3D G3DSA:1.10.730.10 641 816 1.7E-49 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Pfam PF08264 Anticodon-binding domain of tRNA 685 842 1.2E-34 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 641 3.6E-224 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 SUPERFAMILY SSF50677 208 401 3.79E-60 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.3E-31 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 527 540 2.3E-31 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 52 63 2.3E-31 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 561 570 2.3E-31 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 237 260 2.3E-31 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 16 844 0.0 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 SUPERFAMILY SSF52374 401 647 1.56E-157 T 29-03-2018 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 SUPERFAMILY SSF52374 3 203 1.56E-157 T 29-03-2018 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Pfam PF06827 Zinc finger found in FPG and IleRS 899 926 1.2E-8 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Gene3D G3DSA:3.40.50.620 20 640 4.9E-147 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 SUPERFAMILY SSF47323 652 930 1.87E-78 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Gene3D G3DSA:3.30.2320.20 817 897 8.0E-26 T 29-03-2018 HVS_RS07830 b34fe992dd2da0145169f794a9e20217 930 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 3 930 21.179 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 HVS_RS00510 f819c1bb618443e298f160d169c6a789 145 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 6 139 6.9E-57 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HVS_RS00510 f819c1bb618443e298f160d169c6a789 145 Pfam PF07977 FabA-like domain 11 133 3.1E-34 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HVS_RS00510 f819c1bb618443e298f160d169c6a789 145 Gene3D G3DSA:3.10.129.10 2 145 1.7E-54 T 29-03-2018 HVS_RS00510 f819c1bb618443e298f160d169c6a789 145 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 33.389 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HVS_RS00510 f819c1bb618443e298f160d169c6a789 145 SUPERFAMILY SSF54637 6 143 6.84E-50 T 29-03-2018 IPR029069 HotDog domain HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 344 498 7.1E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 345 365 1.1E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 412 430 1.1E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Gene3D G3DSA:1.10.287.510 230 328 0.0016 T 29-03-2018 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 SUPERFAMILY SSF52540 344 526 4.89E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Pfam PF01926 50S ribosome-binding GTPase 345 463 5.2E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Gene3D G3DSA:3.40.50.300 378 550 2.7E-20 T 29-03-2018 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Pfam PF13167 GTP-binding GTPase N-terminal 169 257 3.1E-31 T 29-03-2018 IPR025121 GTPase HflX, N-terminal HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 148 503 2.8E-142 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Hamap MF_00900 GTPase HflX [hflX]. 172 533 48.077 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Gene3D G3DSA:3.40.50.300 329 377 3.3E-14 T 29-03-2018 HVS_RS14530 2f8df03ed4598fde560a8a65a9b746d6 561 Pfam PF16360 GTP-binding GTPase Middle Region 259 337 3.4E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Pfam PF00689 Cation transporting ATPase, C-terminus 709 879 6.6E-49 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 TIGRFAM TIGR01522 ATPase-IIA2_Ca: calcium-transporting P-type ATPase, PMR1-type 18 863 6.2E-241 T 29-03-2018 IPR006413 P-type ATPase, subfamily IIA, PMR1-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Pfam PF00690 Cation transporter/ATPase, N-terminus 19 69 1.3E-16 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SMART SM00831 2 74 4.8E-15 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Pfam PF00122 E1-E2 ATPase 109 297 4.0E-59 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF81665 218 311 1.83E-135 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF81665 18 112 1.83E-135 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF81665 675 883 1.83E-135 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 523 534 3.1E-40 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 555 3.1E-40 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 625 644 3.1E-40 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 3.1E-40 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 3.1E-40 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 661 3.1E-40 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF56784 315 335 5.0E-62 T 29-03-2018 IPR023214 HAD-like domain HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF56784 481 730 5.0E-62 T 29-03-2018 IPR023214 HAD-like domain HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Gene3D G3DSA:3.40.1110.10 280 530 1.8E-60 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Gene3D G3DSA:1.20.1110.10 551 888 3.5E-102 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Gene3D G3DSA:2.70.150.10 12 218 4.2E-51 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 319 325 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 484 502 1.4E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 625 641 1.4E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 657 682 1.4E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 597 613 1.4E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 Pfam PF13246 Cation transport ATPase (P-type) 376 467 6.1E-24 T 29-03-2018 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF81660 324 527 3.43E-59 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 SUPERFAMILY SSF81653 112 217 1.31E-30 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 51 869 2.2E-214 T 29-03-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 81 338 5.0E-51 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 592 715 2.2E-36 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS13070 5d704d4ca6b2a4058b27f58d877deae9 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 424 570 8.3E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS00735 3f3bb810067c4c913d82e3f2ed8a9a42 134 SUPERFAMILY SSF158446 9 123 3.92E-33 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein HVS_RS00735 3f3bb810067c4c913d82e3f2ed8a9a42 134 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 15 122 3.5E-30 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein HVS_RS00735 3f3bb810067c4c913d82e3f2ed8a9a42 134 Gene3D G3DSA:1.20.1440.60 2 126 5.8E-33 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein HVS_RS00735 3f3bb810067c4c913d82e3f2ed8a9a42 134 Pfam PF05635 23S rRNA-intervening sequence protein 11 116 4.8E-30 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 SUPERFAMILY SSF52540 540 721 3.19E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 Gene3D G3DSA:1.10.10.10 198 259 3.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 Gene3D G3DSA:3.40.50.300 479 700 1.2E-21 T 29-03-2018 HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 814 24.268 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 SUPERFAMILY SSF52540 220 452 2.23E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 TIGRFAM TIGR00595 priA: primosomal protein N' 299 812 3.3E-197 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 Gene3D G3DSA:3.40.50.300 260 463 2.0E-26 T 29-03-2018 HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 Pfam PF00271 Helicase conserved C-terminal domain 577 669 1.2E-8 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 SMART SM00490 573 670 1.2E-8 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 SMART SM00487 271 469 2.8E-21 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS07025 5ca2113753cf07852dee6033fedb5974 815 Pfam PF04851 Type III restriction enzyme, res subunit 274 438 1.9E-17 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS15980 8332d1b759f78d8389e0a2e30c1e277e 1036 Pfam PF00395 S-layer homology domain 95 132 4.0E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS15980 8332d1b759f78d8389e0a2e30c1e277e 1036 Gene3D G3DSA:2.60.40.10 231 514 0.0092 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15980 8332d1b759f78d8389e0a2e30c1e277e 1036 Pfam PF13205 Bacterial Ig-like domain 398 484 1.9E-8 T 29-03-2018 IPR032812 SbsA, Ig-like domain HVS_RS15980 8332d1b759f78d8389e0a2e30c1e277e 1036 Gene3D G3DSA:2.60.40.1280 576 719 2.1E-4 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 HVS_RS15980 8332d1b759f78d8389e0a2e30c1e277e 1036 Gene3D G3DSA:2.60.40.1220 946 1032 0.31 T 29-03-2018 HVS_RS15980 8332d1b759f78d8389e0a2e30c1e277e 1036 Pfam PF07532 Bacterial Ig-like domain (group 4) 238 287 2.6E-10 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Gene3D G3DSA:1.10.287.110 2 117 2.8E-37 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Gene3D G3DSA:2.60.260.20 265 375 1.6E-29 T 29-03-2018 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Pfam PF01556 DnaJ C terminal domain 127 343 3.7E-42 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 SUPERFAMILY SSF49493 223 276 1.83E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 SUPERFAMILY SSF49493 119 144 1.83E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Pfam PF00684 DnaJ central domain 153 217 1.6E-14 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 379 41.468 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 SUPERFAMILY SSF49493 269 354 9.03E-23 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 SUPERFAMILY SSF46565 2 105 7.85E-37 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Gene3D G3DSA:2.60.260.20 204 264 5.4E-20 T 29-03-2018 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 359 1.4E-139 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 ProSitePatterns PS00636 Nt-dnaJ domain signature. 48 67 - T 29-03-2018 IPR018253 DnaJ domain, conserved site HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Pfam PF00226 DnaJ domain 6 68 2.5E-28 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 PRINTS PR00625 DnaJ domain signature 63 82 2.0E-31 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 PRINTS PR00625 DnaJ domain signature 26 41 2.0E-31 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 PRINTS PR00625 DnaJ domain signature 43 63 2.0E-31 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 PRINTS PR00625 DnaJ domain signature 8 26 2.0E-31 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 SMART SM00271 5 63 6.1E-32 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 Gene3D G3DSA:2.10.230.10 153 203 6.1E-14 T 29-03-2018 HVS_RS11100 8a3a4314e4922ce7ac3cd3a175a5d5b6 382 SUPERFAMILY SSF57938 140 221 1.31E-19 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HVS_RS15890 531cb4fbfc6d523572586797ff101ff6 299 SUPERFAMILY SSF56563 25 299 5.23E-72 T 29-03-2018 HVS_RS15890 531cb4fbfc6d523572586797ff101ff6 299 Pfam PF05065 Phage capsid family 33 296 1.4E-72 T 29-03-2018 IPR024455 Phage capsid HVS_RS15890 531cb4fbfc6d523572586797ff101ff6 299 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 11 297 6.5E-81 T 29-03-2018 IPR024455 Phage capsid HVS_RS15890 531cb4fbfc6d523572586797ff101ff6 299 Gene3D G3DSA:3.30.2400.10 54 194 4.2E-32 T 29-03-2018 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 SUPERFAMILY SSF52540 461 765 5.83E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Pfam PF07724 AAA domain (Cdc48 subfamily) 513 676 1.6E-51 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 545 563 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 SMART SM00382 511 683 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 SMART SM00382 179 324 5.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 622 636 3.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 515 533 3.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 560 578 3.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 589 607 3.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 SMART SM01086 682 771 2.9E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 682 762 3.6E-27 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Gene3D G3DSA:3.40.50.300 138 322 1.4E-26 T 29-03-2018 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Gene3D G3DSA:1.10.8.60 697 772 2.3E-26 T 29-03-2018 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 SUPERFAMILY SSF52540 141 399 1.03E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Gene3D G3DSA:1.10.8.60 323 461 3.1E-36 T 29-03-2018 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 184 314 2.6E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS02545 7bcdf61a71c7cb5fa2469755480abd2c 772 Gene3D G3DSA:3.40.50.300 462 696 4.6E-50 T 29-03-2018 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 30 506 45.869 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 24 506 7.4E-212 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 Gene3D G3DSA:3.30.930.10 159 503 4.8E-107 T 29-03-2018 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 Pfam PF01336 OB-fold nucleic acid binding domain 72 149 1.5E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 Pfam PF00152 tRNA synthetases class II (D, K and N) 166 503 5.7E-84 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 265 282 3.8E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 202 212 3.8E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 247 260 3.8E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 388 404 3.8E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 218 234 3.8E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 PIRSF PIRSF039101 2 507 8.6E-207 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 SUPERFAMILY SSF50249 22 158 4.93E-41 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 Gene3D G3DSA:2.40.50.140 24 158 4.5E-40 T 29-03-2018 HVS_RS15190 41d215dda1ab513e7853daa8588e6487 507 SUPERFAMILY SSF55681 165 504 6.27E-122 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Gene3D G3DSA:3.30.230.10 581 799 3.0E-66 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Gene3D G3DSA:1.10.8.60 496 580 8.8E-32 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Gene3D G3DSA:1.10.4060.10 124 215 1.7E-25 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 SMART SM00464 12 206 4.0E-59 T 29-03-2018 IPR003111 Lon, substrate-binding domain HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 680 688 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 356 494 6.8E-24 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 12 205 1.0E-38 T 29-03-2018 IPR003111 Lon, substrate-binding domain HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 TIGRFAM TIGR00763 lon: endopeptidase La 14 775 5.2E-302 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 SUPERFAMILY SSF88697 12 204 1.04E-42 T 29-03-2018 IPR015947 PUA-like domain HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 573 776 1.7E-96 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 SUPERFAMILY SSF52540 315 592 1.22E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 SMART SM00382 352 497 4.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 360 379 9.0E-54 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 599 615 9.0E-54 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 748 9.0E-54 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 677 696 9.0E-54 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 707 726 9.0E-54 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Gene3D G3DSA:2.30.130.40 3 118 2.0E-27 T 29-03-2018 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 PIRSF PIRSF001174 2 779 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 SUPERFAMILY SSF54211 599 774 8.72E-56 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Hamap MF_01973 Lon protease [lon]. 13 776 71.698 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 HVS_RS05345 e43727a23e90b2ed52294bc6bf479281 811 Gene3D G3DSA:3.40.50.300 317 495 3.5E-34 T 29-03-2018 HVS_RS11835 b31a04d951885be19544f1f8433b1eef 186 Gene3D G3DSA:3.40.470.10 2 186 6.0E-56 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11835 b31a04d951885be19544f1f8433b1eef 186 SUPERFAMILY SSF52141 3 181 4.58E-60 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11835 b31a04d951885be19544f1f8433b1eef 186 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 180 9.9E-57 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 HVS_RS11835 b31a04d951885be19544f1f8433b1eef 186 SMART SM00987 28 174 1.4E-36 T 29-03-2018 HVS_RS11835 b31a04d951885be19544f1f8433b1eef 186 SMART SM00986 28 174 1.4E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11835 b31a04d951885be19544f1f8433b1eef 186 Pfam PF03167 Uracil DNA glycosylase superfamily 31 174 1.0E-42 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 SMART SM00788 3 423 1.8E-274 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 1.1E-174 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 Pfam PF00709 Adenylosuccinate synthetase 5 422 1.1E-182 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 Gene3D G3DSA:3.90.170.10 265 424 2.3E-69 T 29-03-2018 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 424 194.419 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 Gene3D G3DSA:3.40.440.10 1 149 1.8E-54 T 29-03-2018 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 Gene3D G3DSA:3.40.440.10 150 264 2.8E-24 T 29-03-2018 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 SUPERFAMILY SSF52540 1 423 5.1E-170 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HVS_RS11915 71efd1792719ace47a186a86d2ec00ab 424 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 HVS_RS03250 6eac1fef107c09ca9ace0545b916fc50 306 Pfam PF01551 Peptidase family M23 204 299 8.0E-34 T 29-03-2018 IPR016047 Peptidase M23 HVS_RS03250 6eac1fef107c09ca9ace0545b916fc50 306 SUPERFAMILY SSF51261 171 303 2.09E-58 T 29-03-2018 IPR011055 Duplicated hybrid motif HVS_RS03250 6eac1fef107c09ca9ace0545b916fc50 306 Gene3D G3DSA:2.70.70.10 81 306 9.5E-49 T 29-03-2018 HVS_RS07600 74d8dcc8272e3846843b384f72d8f420 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 259 35.492 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HVS_RS07600 74d8dcc8272e3846843b384f72d8f420 262 SUPERFAMILY SSF51366 33 258 5.06E-87 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS07600 74d8dcc8272e3846843b384f72d8f420 262 Gene3D G3DSA:3.20.20.70 2 261 1.3E-72 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS07600 74d8dcc8272e3846843b384f72d8f420 262 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 32 255 29.89 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HVS_RS07600 74d8dcc8272e3846843b384f72d8f420 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 53 71 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 HVS_RS07600 74d8dcc8272e3846843b384f72d8f420 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 3 257 4.1E-94 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 SUPERFAMILY SSF102645 196 406 9.42E-76 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 Gene3D G3DSA:3.40.50.1950 1 187 6.4E-52 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 Pfam PF02441 Flavoprotein 7 178 4.3E-44 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 Gene3D G3DSA:3.40.50.10300 189 413 3.9E-66 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 199 380 3.9E-72 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 405 2.0E-139 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 HVS_RS11065 6cfa51737327d56886249ae970c22d55 414 SUPERFAMILY SSF52507 2 179 1.57E-59 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HVS_RS15520 418a3328518ea1707ae0a6bd8f3800ee 527 SUPERFAMILY SSF53041 32 176 1.44E-28 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS15520 418a3328518ea1707ae0a6bd8f3800ee 527 Pfam PF13408 Recombinase zinc beta ribbon domain 322 383 8.1E-8 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain HVS_RS15520 418a3328518ea1707ae0a6bd8f3800ee 527 Gene3D G3DSA:3.40.50.1390 25 183 1.8E-35 T 29-03-2018 HVS_RS15520 418a3328518ea1707ae0a6bd8f3800ee 527 SMART SM00857 30 177 7.6E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS15520 418a3328518ea1707ae0a6bd8f3800ee 527 Pfam PF00239 Resolvase, N terminal domain 32 176 4.7E-29 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS15520 418a3328518ea1707ae0a6bd8f3800ee 527 Pfam PF07508 Recombinase 199 307 2.9E-26 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 HVS_RS09905 c0b2168e77f068d7d5910d3251af35a7 96 SUPERFAMILY SSF52540 4 45 9.94E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09905 c0b2168e77f068d7d5910d3251af35a7 96 Gene3D G3DSA:3.40.50.300 39 88 9.5E-6 T 29-03-2018 HVS_RS09905 c0b2168e77f068d7d5910d3251af35a7 96 Pfam PF00005 ABC transporter 17 46 1.9E-7 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS09905 c0b2168e77f068d7d5910d3251af35a7 96 Gene3D G3DSA:3.40.50.300 3 38 7.0E-13 T 29-03-2018 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 SUPERFAMILY SSF88659 125 189 1.57E-19 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 Pfam PF08281 Sigma-70, region 4 134 184 4.0E-21 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 Gene3D G3DSA:1.10.1740.10 2 94 5.3E-28 T 29-03-2018 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 4.5E-43 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 Pfam PF04542 Sigma-70 region 2 26 92 7.7E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 SUPERFAMILY SSF88946 8 108 1.73E-29 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08780 61c0d3670b6c9bb676038f3bf6086f94 201 Gene3D G3DSA:1.10.10.10 95 191 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 Gene3D G3DSA:3.30.1490.20 111 194 9.7E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 SUPERFAMILY SSF51246 314 386 2.12E-14 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 Gene3D G3DSA:3.30.470.20 195 386 5.1E-41 T 29-03-2018 HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 Pfam PF02222 ATP-grasp domain 120 289 9.2E-56 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 Gene3D G3DSA:3.40.50.20 13 99 9.8E-26 T 29-03-2018 HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 370 41.198 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 SUPERFAMILY SSF52440 12 107 1.87E-31 T 29-03-2018 IPR016185 Pre-ATP-grasp domain HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 SUPERFAMILY SSF56059 111 310 2.47E-60 T 29-03-2018 HVS_RS07955 5c69c3ac8eadb44bfff320f7a8854884 390 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 373 6.6E-123 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 HVS_RS14040 4a0a6fed5df70af567e069a6d1959108 366 Gene3D G3DSA:3.40.50.2000 3 176 1.0E-12 T 29-03-2018 HVS_RS14040 4a0a6fed5df70af567e069a6d1959108 366 Gene3D G3DSA:3.40.50.2000 177 347 3.2E-42 T 29-03-2018 HVS_RS14040 4a0a6fed5df70af567e069a6d1959108 366 SUPERFAMILY SSF53756 6 364 5.42E-74 T 29-03-2018 HVS_RS14040 4a0a6fed5df70af567e069a6d1959108 366 Pfam PF13439 Glycosyltransferase Family 4 15 166 7.9E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS14040 4a0a6fed5df70af567e069a6d1959108 366 Pfam PF00534 Glycosyl transferases group 1 174 341 9.4E-36 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS01975 88d892137cb725c2a6de7b89bd30cd99 138 SUPERFAMILY SSF51294 93 137 2.09E-8 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS01975 88d892137cb725c2a6de7b89bd30cd99 138 Gene3D G3DSA:2.170.16.10 92 138 8.8E-11 T 29-03-2018 HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 192 7.4E-60 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 4 181 9.2E-54 T 29-03-2018 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 SMART SM00855 3 157 1.4E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 Gene3D G3DSA:3.40.50.1240 1 196 1.8E-55 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 PIRSF PIRSF000709 3 183 2.4E-18 T 29-03-2018 HVS_RS12170 ae1f5886491f761dd743a3ade5ed6c27 196 SUPERFAMILY SSF53254 1 194 1.7E-60 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS07155 3a47dd6cec4a6a432cf2dff4535ffbed 204 TIGRFAM TIGR02354 thiF_fam2: thiamine biosynthesis protein ThiF 16 198 1.4E-57 T 29-03-2018 IPR012729 Thiamine biosynthesis protein ThiF HVS_RS07155 3a47dd6cec4a6a432cf2dff4535ffbed 204 SUPERFAMILY SSF69572 11 200 1.96E-44 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HVS_RS07155 3a47dd6cec4a6a432cf2dff4535ffbed 204 Gene3D G3DSA:3.40.50.720 7 188 3.1E-40 T 29-03-2018 HVS_RS07155 3a47dd6cec4a6a432cf2dff4535ffbed 204 Pfam PF00899 ThiF family 13 150 2.8E-34 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HVS_RS13560 5e93ca0f59307c73eea14b2c41b725f2 134 Gene3D G3DSA:3.40.50.1010 1 132 5.9E-15 T 29-03-2018 IPR029060 PIN domain-like HVS_RS13560 5e93ca0f59307c73eea14b2c41b725f2 134 Pfam PF13470 PIN domain 2 112 3.3E-13 T 29-03-2018 IPR002716 PIN domain HVS_RS13560 5e93ca0f59307c73eea14b2c41b725f2 134 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 115 4.4E-12 T 29-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component HVS_RS13560 5e93ca0f59307c73eea14b2c41b725f2 134 SMART SM00670 1 116 3.2E-6 T 29-03-2018 IPR002716 PIN domain HVS_RS13560 5e93ca0f59307c73eea14b2c41b725f2 134 SUPERFAMILY SSF88723 1 120 8.41E-14 T 29-03-2018 IPR029060 PIN domain-like HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 SUPERFAMILY SSF55957 730 814 4.97E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 382 512 1.1E-23 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:3.40.120.10 381 525 7.8E-21 T 29-03-2018 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:3.40.120.10 632 725 3.9E-9 T 29-03-2018 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:3.40.120.10 526 631 6.9E-4 T 29-03-2018 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:2.160.10.10 308 380 2.7E-8 T 29-03-2018 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:2.160.10.10 234 307 1.0E-13 T 29-03-2018 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 SUPERFAMILY SSF53738 630 727 1.49E-9 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 SUPERFAMILY SSF51161 243 422 7.07E-30 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 249 283 9.8E-7 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 SUPERFAMILY SSF53738 375 515 8.24E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Pfam PF00483 Nucleotidyl transferase 2 233 3.1E-53 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:3.90.550.10 1 233 1.6E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 SUPERFAMILY SSF53448 1 261 1.11E-79 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS07350 9f5f97b71ba2a65b7d69bef8614bc4c6 817 Gene3D G3DSA:3.30.310.50 726 817 1.7E-6 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 513 531 9.1E-17 T 29-03-2018 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 598 614 9.1E-17 T 29-03-2018 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 472 490 9.1E-17 T 29-03-2018 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 390 409 9.1E-17 T 29-03-2018 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 Gene3D G3DSA:3.50.50.60 403 489 4.9E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 343 5.3E-76 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 Gene3D G3DSA:3.20.20.70 2 371 1.2E-122 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 Gene3D G3DSA:3.50.50.60 490 621 1.7E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 SUPERFAMILY SSF51395 5 372 2.17E-112 T 29-03-2018 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 509 533 7.0E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 600 621 7.0E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 389 411 7.0E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 SUPERFAMILY SSF51905 365 650 1.36E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 Gene3D G3DSA:3.90.180.10 372 402 0.0074 T 29-03-2018 HVS_RS13055 c77ccede30157d61e8303f01e120aac7 650 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 389 615 1.8E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS03240 ca65abb9b81fe11d3e22b032ee6cf1a4 225 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 127 215 3.7E-33 T 29-03-2018 IPR014197 Sporulation protein YunB HVS_RS03240 ca65abb9b81fe11d3e22b032ee6cf1a4 225 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 24 219 6.9E-54 T 29-03-2018 IPR014197 Sporulation protein YunB HVS_RS03240 ca65abb9b81fe11d3e22b032ee6cf1a4 225 PIRSF PIRSF021383 1 224 9.5E-60 T 29-03-2018 IPR014197 Sporulation protein YunB HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 TIGRFAM TIGR00433 bioB: biotin synthase 35 324 3.1E-121 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 SMART SM00729 59 265 2.5E-43 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 PIRSF PIRSF001619 1 326 9.6E-114 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 Hamap MF_01694 Biotin synthase [bioB]. 16 326 42.124 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 SMART SM00876 236 326 3.5E-32 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 SUPERFAMILY SSF102114 16 325 1.31E-75 T 29-03-2018 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 Gene3D G3DSA:3.20.20.70 1 322 3.3E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 324 9.1E-17 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS08580 f90844aef805c8e419c734dd8856e751 326 Pfam PF04055 Radical SAM superfamily 68 224 1.9E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Pfam PF00575 S1 RNA binding domain 621 699 1.4E-10 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Pfam PF08206 Ribonuclease B OB domain 143 198 1.1E-9 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Pfam PF08206 Ribonuclease B OB domain 71 129 3.2E-19 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 58 703 6.2E-209 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 ProSitePatterns PS01175 Ribonuclease II family signature. 541 565 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SMART SM00955 245 574 7.3E-176 T 29-03-2018 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SUPERFAMILY SSF50249 623 702 1.17E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SUPERFAMILY SSF50249 205 621 3.86E-145 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SMART SM00316 621 703 6.8E-14 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SUPERFAMILY SSF50249 52 132 1.03E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SUPERFAMILY SSF50249 123 222 4.52E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 TIGRFAM TIGR02063 RNase_R: ribonuclease R 4 704 1.8E-266 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Hamap MF_01895 Ribonuclease R [rnr]. 22 703 58.424 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Gene3D G3DSA:1.10.10.10 2 57 4.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SMART SM00357 135 199 2.8E-8 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 SMART SM00357 70 130 8.6E-9 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Pfam PF00773 RNB domain 245 573 1.1E-115 T 29-03-2018 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Gene3D G3DSA:2.40.50.140 58 122 0.032 T 29-03-2018 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Gene3D G3DSA:2.40.50.140 123 208 5.6E-4 T 29-03-2018 HVS_RS11625 dab80cadcd1e9a4a2c583cd7af67f929 747 Gene3D G3DSA:2.40.50.140 620 704 6.7E-19 T 29-03-2018 HVS_RS08570 8c00904d8dc609f2a66493773fb85dcf 241 Pfam PF00561 alpha/beta hydrolase fold 57 231 6.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 HVS_RS08570 8c00904d8dc609f2a66493773fb85dcf 241 SUPERFAMILY SSF53474 5 240 3.92E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS08570 8c00904d8dc609f2a66493773fb85dcf 241 Gene3D G3DSA:3.40.50.1820 3 241 6.0E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS13090 3aeea32f181c37b6566f62656f4eb18d 380 SUPERFAMILY SSF158634 257 304 1.44E-6 T 29-03-2018 HVS_RS13090 3aeea32f181c37b6566f62656f4eb18d 380 SUPERFAMILY SSF158634 328 374 5.62E-8 T 29-03-2018 HVS_RS13090 3aeea32f181c37b6566f62656f4eb18d 380 Gene3D G3DSA:3.90.1720.10 36 234 2.8E-5 T 29-03-2018 HVS_RS09595 b7de332644ea3e39c85dcd10faddf576 226 Gene3D G3DSA:3.20.20.70 8 216 2.8E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS09595 b7de332644ea3e39c85dcd10faddf576 226 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 190 2.3E-65 T 29-03-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein HVS_RS09595 b7de332644ea3e39c85dcd10faddf576 226 Pfam PF13353 4Fe-4S single cluster domain 15 127 3.0E-12 T 29-03-2018 HVS_RS09595 b7de332644ea3e39c85dcd10faddf576 226 SUPERFAMILY SSF102114 14 205 7.72E-25 T 29-03-2018 HVS_RS09595 b7de332644ea3e39c85dcd10faddf576 226 Pfam PF04055 Radical SAM superfamily 21 177 2.2E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS10065 a20c6f92c3221f066e132b6a94bc1b18 252 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 17 242 26.992 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS10065 a20c6f92c3221f066e132b6a94bc1b18 252 PIRSF PIRSF038953 9 251 2.8E-74 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS10065 a20c6f92c3221f066e132b6a94bc1b18 252 SUPERFAMILY SSF88946 23 106 5.23E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10065 a20c6f92c3221f066e132b6a94bc1b18 252 Gene3D G3DSA:1.10.1740.10 20 105 1.9E-13 T 29-03-2018 HVS_RS10065 a20c6f92c3221f066e132b6a94bc1b18 252 Pfam PF04542 Sigma-70 region 2 36 107 3.5E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10065 a20c6f92c3221f066e132b6a94bc1b18 252 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 23 239 1.4E-64 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 256 273 2.2E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 36 58 2.2E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 300 315 2.2E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 330 351 2.2E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 236 254 2.2E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 Gene3D G3DSA:3.40.1690.10 246 381 1.7E-57 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 Pfam PF01312 FlhB HrpN YscU SpaS Family 33 375 5.7E-132 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 34 380 1.0E-125 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 HVS_RS10165 534316e0096c3eea59d6770543ca10cf 385 SUPERFAMILY SSF160544 272 379 9.42E-42 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 109 709 1.3E-265 T 29-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 Gene3D G3DSA:3.40.50.2000 424 735 6.2E-88 T 29-03-2018 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 Gene3D G3DSA:3.40.50.2000 65 256 2.4E-32 T 29-03-2018 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 Gene3D G3DSA:3.40.50.2000 267 423 9.9E-48 T 29-03-2018 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 PIRSF PIRSF000460 1 797 1.0E-281 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 Pfam PF00343 Carbohydrate phosphorylase 272 620 1.1E-27 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 Pfam PF11897 Protein of unknown function (DUF3417) 13 122 2.6E-39 T 29-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HVS_RS12315 21227dfdc1fa05abea71a7fe4e5b93bc 855 SUPERFAMILY SSF53756 4 742 2.51E-219 T 29-03-2018 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 SUPERFAMILY SSF101898 1408 1600 4.97E-8 T 29-03-2018 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 SUPERFAMILY SSF51294 2071 2204 1.83E-25 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1859 1939 3.8E-17 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Gene3D G3DSA:2.60.40.680 354 511 2.0E-23 T 29-03-2018 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF00395 S-layer homology domain 66 107 4.4E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF00395 S-layer homology domain 126 162 3.2E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF00395 S-layer homology domain 193 230 6.3E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Gene3D G3DSA:2.60.40.10 512 612 0.019 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Gene3D G3DSA:2.60.40.10 616 713 5.9E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Gene3D G3DSA:2.130.10.10 1244 1619 3.6E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1537 1577 2.5E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1093 1124 4.4E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1223 1260 1.9E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1265 1300 4.9E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1578 1619 2.9E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1496 1536 0.0017 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1134 1174 5.1E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1328 1365 1.7E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 945 980 8.5E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1412 1453 2.6E-11 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1051 1092 1.0E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1370 1410 2.3E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1307 1348 5.3E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 913 944 9.1E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1030 1069 1.2E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Gene3D G3DSA:2.130.10.10 798 1202 1.3E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1030 1062 7.4E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1134 1170 6.6E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1391 1427 1.3E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1578 1615 2.5E-10 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1051 1088 1.8E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1728 1758 7.1E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1349 1385 1.3E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1475 1511 9.2E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1328 1364 2.0E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 945 980 5.9E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1093 1122 1.2E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1223 1260 8.0E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 925 952 3.8E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1433 1468 4.0E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1541 1574 9.6E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1307 1343 3.0E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF05593 RHS Repeat 1265 1301 4.8E-10 T 29-03-2018 IPR031325 RHS repeat HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 SMART SM00306 2069 2163 9.1E-14 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Gene3D G3DSA:2.170.16.10 2058 2205 5.6E-38 T 29-03-2018 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 SUPERFAMILY SSF49384 369 504 6.02E-22 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2182 2206 0.0041 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF07591 Pretoxin HINT domain 2077 2206 4.2E-29 T 29-03-2018 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 Pfam PF00963 Cohesin domain 370 504 1.5E-24 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS03755 234b5f83af013491ae9aa17edd59c365 2315 SUPERFAMILY SSF69304 882 1120 2.75E-7 T 29-03-2018 HVS_RS02735 b53d4b11e13842f22af777702af65718 109 Pfam PF07085 DRTGG domain 7 102 8.2E-9 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HVS_RS02735 b53d4b11e13842f22af777702af65718 109 SUPERFAMILY SSF75138 1 103 9.16E-19 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HVS_RS02735 b53d4b11e13842f22af777702af65718 109 Gene3D G3DSA:3.40.1390.20 1 109 5.3E-17 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 634 55.055 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Gene3D G3DSA:3.30.65.10 654 699 3.2E-4 T 29-03-2018 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Gene3D G3DSA:3.30.65.10 617 653 9.9E-8 T 29-03-2018 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Gene3D G3DSA:3.30.65.10 561 616 9.7E-17 T 29-03-2018 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Gene3D G3DSA:3.40.50.140 2 129 2.2E-38 T 29-03-2018 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 1.7E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 372 388 1.7E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.7E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 295 304 1.7E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 475 489 1.7E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Gene3D G3DSA:2.70.20.10 329 458 5.6E-44 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Pfam PF01131 DNA topoisomerase 127 549 3.7E-136 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 SMART SM00493 3 103 4.2E-34 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS10285 f713b038e9264883449cc72f73278b39 699 SUPERFAMILY SSF56712 3 591 1.1E-202 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Gene3D G3DSA:1.10.460.10 135 328 1.4E-48 T 29-03-2018 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 SMART SM00437 244 512 1.2E-123 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 281 304 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 SUPERFAMILY SSF57783 573 614 7.4E-14 T 29-03-2018 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 612 1.9E-258 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 579 613 6.7E-14 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 690 0.012 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 619 656 2.9E-10 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 HVS_RS10285 f713b038e9264883449cc72f73278b39 699 Pfam PF01751 Toprim domain 5 113 2.1E-30 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS10285 f713b038e9264883449cc72f73278b39 699 SMART SM00436 104 192 3.5E-51 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 SUPERFAMILY SSF53738 35 240 3.22E-49 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 SUPERFAMILY SSF55957 454 485 1.07E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 SUPERFAMILY SSF55957 517 577 1.07E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 46 183 5.6E-43 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Gene3D G3DSA:3.30.310.50 471 581 7.9E-23 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Gene3D G3DSA:3.40.120.10 216 341 8.2E-33 T 29-03-2018 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 SUPERFAMILY SSF53738 308 458 9.03E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Gene3D G3DSA:3.40.120.10 20 215 1.8E-60 T 29-03-2018 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 328 452 5.9E-24 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 SUPERFAMILY SSF53738 210 319 1.22E-21 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 212 316 2.3E-24 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 477 557 3.9E-8 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 Gene3D G3DSA:3.40.120.10 342 459 2.5E-38 T 29-03-2018 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 141 155 3.1E-8 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 252 3.1E-8 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS10735 e56143f3a29ae9663c80d1d4ebc6272b 585 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 300 315 3.1E-8 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HVS_RS03590 06c0960928ba260c2cd58a0523837876 230 Pfam PF13546 DDE superfamily endonuclease 18 200 9.2E-15 T 29-03-2018 HVS_RS03590 06c0960928ba260c2cd58a0523837876 230 SUPERFAMILY SSF53098 3 196 5.69E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS03590 06c0960928ba260c2cd58a0523837876 230 Gene3D G3DSA:3.90.350.10 13 218 1.2E-14 T 29-03-2018 IPR014736 Transposase, Tn5-like, core HVS_RS01560 7076e104ecfd64cda7f468cb3bcd5960 490 Pfam PF00665 Integrase core domain 125 251 2.5E-20 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS01560 7076e104ecfd64cda7f468cb3bcd5960 490 Gene3D G3DSA:1.10.10.60 93 118 0.18 T 29-03-2018 HVS_RS01560 7076e104ecfd64cda7f468cb3bcd5960 490 Gene3D G3DSA:3.30.420.10 119 345 2.4E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01560 7076e104ecfd64cda7f468cb3bcd5960 490 SUPERFAMILY SSF53098 125 290 8.16E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01560 7076e104ecfd64cda7f468cb3bcd5960 490 Gene3D G3DSA:1.10.10.60 58 92 0.027 T 29-03-2018 HVS_RS01560 7076e104ecfd64cda7f468cb3bcd5960 490 Gene3D G3DSA:1.10.10.60 4 57 0.001 T 29-03-2018 HVS_RS10215 4edc43feb881050bb0ee1a6f7ecd4cef 440 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 359 438 1.4E-21 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HVS_RS10215 4edc43feb881050bb0ee1a6f7ecd4cef 440 Pfam PF07559 Flagellar basal body protein FlaE 204 319 5.2E-12 T 29-03-2018 IPR011491 Flagellar hook protein FlgE HVS_RS10215 4edc43feb881050bb0ee1a6f7ecd4cef 440 Gene3D G3DSA:2.60.98.20 179 320 8.7E-23 T 29-03-2018 IPR011491 Flagellar hook protein FlgE HVS_RS10215 4edc43feb881050bb0ee1a6f7ecd4cef 440 Pfam PF00460 Flagella basal body rod protein 8 35 1.3E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HVS_RS10215 4edc43feb881050bb0ee1a6f7ecd4cef 440 SUPERFAMILY SSF117143 93 400 6.41E-64 T 29-03-2018 HVS_RS10215 4edc43feb881050bb0ee1a6f7ecd4cef 440 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 421 8.4E-90 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HVS_RS00660 ec87867afc4afda46bf4787c5798cf00 113 SUPERFAMILY SSF82607 17 111 4.45E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HVS_RS00660 ec87867afc4afda46bf4787c5798cf00 113 Gene3D G3DSA:3.30.1310.10 5 113 1.0E-39 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HVS_RS00660 ec87867afc4afda46bf4787c5798cf00 113 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 11 105 23.361 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HVS_RS00660 ec87867afc4afda46bf4787c5798cf00 113 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 11 111 1.3E-30 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HVS_RS00660 ec87867afc4afda46bf4787c5798cf00 113 Pfam PF02575 YbaB/EbfC DNA-binding family 17 106 8.6E-37 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HVS_RS00660 ec87867afc4afda46bf4787c5798cf00 113 PIRSF PIRSF004555 9 113 3.5E-40 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family HVS_RS00870 387cf4afd108f438082af9754bf85fa7 1374 SUPERFAMILY SSF54001 254 291 2.62E-19 T 29-03-2018 HVS_RS00870 387cf4afd108f438082af9754bf85fa7 1374 SUPERFAMILY SSF54001 143 209 2.62E-19 T 29-03-2018 HVS_RS00870 387cf4afd108f438082af9754bf85fa7 1374 Pfam PF01841 Transglutaminase-like superfamily 142 284 1.2E-18 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS00870 387cf4afd108f438082af9754bf85fa7 1374 Gene3D G3DSA:3.90.260.10 172 308 3.5E-4 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS00870 387cf4afd108f438082af9754bf85fa7 1374 Gene3D G3DSA:1.25.40.20 919 1187 3.8E-4 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain HVS_RS15015 4c982bffc5c7c88a6d5f4d69844cad2b 37 SUPERFAMILY SSF57840 1 37 4.58E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15015 4c982bffc5c7c88a6d5f4d69844cad2b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.996 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15015 4c982bffc5c7c88a6d5f4d69844cad2b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 1.6E-23 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15015 4c982bffc5c7c88a6d5f4d69844cad2b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 29-03-2018 HVS_RS15015 4c982bffc5c7c88a6d5f4d69844cad2b 37 Pfam PF00444 Ribosomal protein L36 1 37 2.2E-19 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15015 4c982bffc5c7c88a6d5f4d69844cad2b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS07330 2a053a0e259afa946b0042270b6c0139 341 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 26 335 1.0E-92 T 29-03-2018 IPR014255 Spore coat protein CotS HVS_RS07330 2a053a0e259afa946b0042270b6c0139 341 Gene3D G3DSA:3.30.200.20 1 105 2.8E-19 T 29-03-2018 HVS_RS07330 2a053a0e259afa946b0042270b6c0139 341 SUPERFAMILY SSF56112 10 306 4.85E-41 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS07330 2a053a0e259afa946b0042270b6c0139 341 Pfam PF01636 Phosphotransferase enzyme family 26 250 5.1E-12 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase HVS_RS07330 2a053a0e259afa946b0042270b6c0139 341 Gene3D G3DSA:3.90.1200.10 106 337 2.3E-23 T 29-03-2018 HVS_RS01425 1d1b6e33bcea0687dcff25400a00cd04 337 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 1 328 1.9E-165 T 29-03-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00010+4.2.1.11|KEGG: 00520+4.2.1.115|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6143|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 HVS_RS01425 1d1b6e33bcea0687dcff25400a00cd04 337 Gene3D G3DSA:3.40.50.720 1 336 1.8E-57 T 29-03-2018 HVS_RS01425 1d1b6e33bcea0687dcff25400a00cd04 337 SUPERFAMILY SSF51735 1 279 1.06E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS01425 1d1b6e33bcea0687dcff25400a00cd04 337 Pfam PF02719 Polysaccharide biosynthesis protein 7 286 5.4E-104 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 Gene3D G3DSA:2.40.50.140 380 444 9.5E-18 T 29-03-2018 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 SMART SM00729 146 364 9.6E-56 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 3 441 66.163 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 Pfam PF04055 Radical SAM superfamily 152 322 1.2E-25 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 Pfam PF00919 Uncharacterized protein family UPF0004 4 101 1.0E-28 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 Gene3D G3DSA:3.80.30.20 143 378 1.5E-47 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 SUPERFAMILY SSF102114 142 369 3.53E-56 T 29-03-2018 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 439 1.7E-133 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HVS_RS08850 736def7c22d780b04603ed3ddbe5f4e4 447 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 4 439 1.2E-153 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 HVS_RS16200 5d4d8f259174cb8f0553f3e4dd1244e0 112 Pfam PF00825 Ribonuclease P 1 107 4.8E-29 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HVS_RS16200 5d4d8f259174cb8f0553f3e4dd1244e0 112 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 110 17.972 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HVS_RS16200 5d4d8f259174cb8f0553f3e4dd1244e0 112 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 85 1.0E-23 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HVS_RS16200 5d4d8f259174cb8f0553f3e4dd1244e0 112 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 108 1.7E-25 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HVS_RS16200 5d4d8f259174cb8f0553f3e4dd1244e0 112 Gene3D G3DSA:3.30.230.10 1 112 6.2E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS16200 5d4d8f259174cb8f0553f3e4dd1244e0 112 SUPERFAMILY SSF54211 1 109 7.59E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 156 259 2.9E-47 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 Gene3D G3DSA:1.10.10.10 152 262 1.0E-54 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 PIRSF PIRSF002937 1 266 2.6E-130 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 156 264 9.0E-57 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 SUPERFAMILY SSF52172 5 126 4.98E-30 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 Pfam PF00072 Response regulator receiver domain 8 122 2.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 SMART SM00448 6 121 1.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 4 265 1.2E-125 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 Gene3D G3DSA:3.40.50.2300 5 144 2.5E-28 T 29-03-2018 HVS_RS09700 049f23d329bdf96ecbdbd0174a6f122f 267 SUPERFAMILY SSF46894 149 264 5.36E-50 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS09220 79de63ac47ad1044c79063002bca5c12 255 Pfam PF01351 Ribonuclease HII 75 251 4.6E-41 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain HVS_RS09220 79de63ac47ad1044c79063002bca5c12 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 252 36.866 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 HVS_RS09220 79de63ac47ad1044c79063002bca5c12 255 Gene3D G3DSA:3.30.420.10 49 253 1.4E-71 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS09220 79de63ac47ad1044c79063002bca5c12 255 SUPERFAMILY SSF53098 62 250 1.26E-67 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS10665 2a3a57b3ab02a9983182fd3cc0f437fc 66 SUPERFAMILY SSF57829 1 50 1.16E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 HVS_RS10665 2a3a57b3ab02a9983182fd3cc0f437fc 66 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 50 8.5E-24 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10665 2a3a57b3ab02a9983182fd3cc0f437fc 66 Pfam PF01783 Ribosomal L32p protein family 2 53 1.3E-24 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10665 2a3a57b3ab02a9983182fd3cc0f437fc 66 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 63 20.258 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 31 263 1.4E-51 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 106 9.4E-12 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 Gene3D G3DSA:3.40.1280.10 102 264 4.4E-44 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 SUPERFAMILY SSF75217 95 263 1.37E-44 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 Pfam PF00588 SpoU rRNA Methylase family 117 256 3.9E-36 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 Gene3D G3DSA:3.30.1330.30 3 101 1.9E-21 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 SMART SM00967 31 107 1.5E-13 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HVS_RS06410 2d039e51ccdb68117ab562a8c2990281 264 SUPERFAMILY SSF55315 2 105 6.0E-21 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS00575 521255e53c49e66be8a5d5d579620f96 169 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 13 90 7.2E-23 T 29-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like HVS_RS00575 521255e53c49e66be8a5d5d579620f96 169 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 5 126 6.0E-23 T 29-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 3.4E-51 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 PIRSF PIRSF000447 1 410 9.4E-161 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 SUPERFAMILY SSF53901 3 250 1.87E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 SUPERFAMILY SSF53901 213 409 4.53E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 SMART SM00825 Beta-ketoacyl synthase 5 410 2.0E-14 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 1.6E-35 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 1.4E-173 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 Gene3D G3DSA:3.40.47.10 1 257 3.9E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08555 8b03541a94b380bd9c539592558cc2f4 410 Gene3D G3DSA:3.40.47.10 261 410 2.0E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 Gene3D G3DSA:3.60.15.10 1 448 4.5E-64 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 Hamap MF_01491 Ribonuclease J [rnj]. 3 555 48.422 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 355 413 7.4E-11 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 Pfam PF00753 Metallo-beta-lactamase superfamily 18 164 2.3E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 SUPERFAMILY SSF56281 8 424 2.16E-99 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 SMART SM00849 20 215 1.9E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 1.5E-205 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HVS_RS11010 2706c051f0eb0f14bf3a3e3525400e14 555 PIRSF PIRSF004803 1 555 1.5E-248 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 Pfam PF14266 Putative component of 'biosynthetic module' 1 129 4.5E-27 T 29-03-2018 IPR025647 Putative component of 'biosynthetic module' HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 Pfam PF13365 Trypsin-like peptidase domain 199 331 3.6E-25 T 29-03-2018 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 8.8E-15 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 PRINTS PR00834 HtrA/DegQ protease family signature 272 296 8.8E-15 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 PRINTS PR00834 HtrA/DegQ protease family signature 208 220 8.8E-15 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 PRINTS PR00834 HtrA/DegQ protease family signature 233 253 8.8E-15 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 Gene3D G3DSA:2.40.10.10 270 357 1.0E-24 T 29-03-2018 HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 SUPERFAMILY SSF50494 176 357 1.66E-40 T 29-03-2018 IPR009003 Peptidase S1, PA clan HVS_RS06900 eea8d06634902b9895c9ff8e5e371600 471 Gene3D G3DSA:2.40.10.10 167 269 1.3E-18 T 29-03-2018 HVS_RS04810 48637a4ec75a23c6158314130b753eef 396 SUPERFAMILY SSF110221 254 392 1.96E-43 T 29-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 HVS_RS04810 48637a4ec75a23c6158314130b753eef 396 Gene3D G3DSA:2.80.10.50 230 272 0.16 T 29-03-2018 HVS_RS04810 48637a4ec75a23c6158314130b753eef 396 Pfam PF12791 Anti-sigma factor N-terminus 8 61 9.9E-11 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS04810 48637a4ec75a23c6158314130b753eef 396 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 263 390 8.7E-40 T 29-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 HVS_RS04810 48637a4ec75a23c6158314130b753eef 396 Gene3D G3DSA:2.80.10.50 273 395 4.4E-40 T 29-03-2018 HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 Gene3D G3DSA:3.40.250.10 62 209 2.0E-28 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 Gene3D G3DSA:3.40.250.10 210 341 3.1E-20 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 SMART SM00450 214 337 4.0E-10 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 SMART SM00450 67 193 6.8E-16 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 SUPERFAMILY SSF52821 64 208 2.75E-28 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 SUPERFAMILY SSF52821 213 333 1.7E-25 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 Pfam PF00581 Rhodanese-like domain 68 189 3.7E-18 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS00590 0893ef404f6e866a940a5ddfbf2f636f 341 Pfam PF00581 Rhodanese-like domain 219 333 5.2E-12 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS15595 fb0267029c9215b620de12b855ffd54b 485 SUPERFAMILY SSF102114 120 300 5.69E-10 T 29-03-2018 HVS_RS15595 fb0267029c9215b620de12b855ffd54b 485 Gene3D G3DSA:2.30.42.10 9 112 1.3E-9 T 29-03-2018 HVS_RS15595 fb0267029c9215b620de12b855ffd54b 485 Gene3D G3DSA:3.20.20.70 150 360 2.2E-8 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS15595 fb0267029c9215b620de12b855ffd54b 485 SUPERFAMILY SSF50156 36 117 9.99E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS15595 fb0267029c9215b620de12b855ffd54b 485 Pfam PF04459 Protein of unknown function (DUF512) 254 469 3.1E-79 T 29-03-2018 IPR007549 Domain of unknown function DUF512 HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 Gene3D G3DSA:3.40.50.980 2 194 3.9E-36 T 29-03-2018 HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 522 8.3E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 Gene3D G3DSA:2.30.38.10 355 433 3.2E-25 T 29-03-2018 HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 Gene3D G3DSA:3.40.50.980 195 354 3.1E-30 T 29-03-2018 HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 SUPERFAMILY SSF56801 3 534 1.57E-138 T 29-03-2018 HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 29-03-2018 IPR020845 AMP-binding, conserved site HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 Gene3D G3DSA:3.30.300.30 435 541 3.0E-24 T 29-03-2018 HVS_RS10815 79e9938c6eb49db3a5977f58b07e9526 552 Pfam PF00501 AMP-binding enzyme 50 440 2.8E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 293 8.2E-79 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 Gene3D G3DSA:3.40.1380.10 27 246 7.1E-60 T 29-03-2018 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 PRINTS PR00126 ATP synthase gamma subunit signature 272 293 1.2E-26 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 PRINTS PR00126 ATP synthase gamma subunit signature 241 260 1.2E-26 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 PRINTS PR00126 ATP synthase gamma subunit signature 78 97 1.2E-26 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 1.2E-26 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 294 28.806 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 280 293 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 Pfam PF00231 ATP synthase 3 293 3.1E-81 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 SUPERFAMILY SSF52943 3 293 1.7E-68 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03650 c70941d8eb0746a5c7b9e08c8a2b9180 305 Gene3D G3DSA:1.10.287.80 247 289 8.7E-10 T 29-03-2018 HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 SUPERFAMILY SSF52317 5 224 9.17E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Pfam PF00117 Glutamine amidotransferase class-I 8 187 1.2E-30 T 29-03-2018 IPR017926 Glutamine amidotransferase HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Gene3D G3DSA:3.40.50.620 195 385 3.4E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 191 5.2E-55 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Gene3D G3DSA:3.40.50.880 3 188 2.2E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Pfam PF02540 NAD synthase 202 242 6.4E-6 T 29-03-2018 IPR022310 NAD/GMP synthase HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 510 51.291 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 200 510 2.6E-152 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 SUPERFAMILY SSF52402 180 432 1.67E-59 T 29-03-2018 HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Gene3D G3DSA:3.30.300.10 386 510 2.5E-52 T 29-03-2018 HVS_RS06215 fe6d24385d8fc526d71ffbf083806e42 510 Pfam PF00958 GMP synthase C terminal domain 418 509 3.8E-43 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 170 187 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 326 338 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 202 219 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 219 229 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 149 161 1.6E-54 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Gene3D G3DSA:3.30.930.10 236 362 8.2E-48 T 29-03-2018 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Gene3D G3DSA:3.30.930.10 4 104 5.6E-21 T 29-03-2018 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Gene3D G3DSA:3.30.930.10 121 235 8.3E-34 T 29-03-2018 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 244 3.1E-94 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 4 461 52.596 T 29-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 SUPERFAMILY SSF52954 358 461 2.27E-32 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Pfam PF03129 Anticodon binding domain 371 458 6.7E-22 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Gene3D G3DSA:3.40.50.800 363 461 1.1E-24 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 163 412 1.5E-10 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS11060 d8e4c1c63c7a83ed67281dec5b158c2f 462 SUPERFAMILY SSF55681 6 374 2.49E-132 T 29-03-2018 HVS_RS13940 faf1e02ed7f0a7f25ee83dc5eaf6c439 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 280 3.9E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS13940 faf1e02ed7f0a7f25ee83dc5eaf6c439 282 Gene3D G3DSA:1.10.3720.10 9 269 3.5E-34 T 29-03-2018 HVS_RS13940 faf1e02ed7f0a7f25ee83dc5eaf6c439 282 SUPERFAMILY SSF161098 70 261 1.83E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 Gene3D G3DSA:3.90.1170.30 109 128 0.45 T 29-03-2018 HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 SUPERFAMILY SSF51230 53 127 1.7E-24 T 29-03-2018 IPR011053 Single hybrid motif HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 Gene3D G3DSA:2.40.50.100 5 68 0.26 T 29-03-2018 HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 Gene3D G3DSA:2.40.50.100 89 108 2.5E-5 T 29-03-2018 HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 Gene3D G3DSA:2.40.50.100 69 88 1.9E-14 T 29-03-2018 HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 Pfam PF00364 Biotin-requiring enzyme 61 127 7.4E-23 T 29-03-2018 IPR000089 Biotin/lipoyl attachment HVS_RS08140 b1bee8e117013a4a3aabd0ca91c84e80 128 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 84 101 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 HVS_RS12665 a8499ac679ec73137201fcabb7e19a53 341 Pfam PF00793 DAHP synthetase I family 86 323 1.9E-75 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HVS_RS12665 a8499ac679ec73137201fcabb7e19a53 341 Gene3D G3DSA:3.30.70.1140 1 70 6.6E-23 T 29-03-2018 HVS_RS12665 a8499ac679ec73137201fcabb7e19a53 341 Gene3D G3DSA:3.20.20.70 71 333 2.0E-79 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS12665 a8499ac679ec73137201fcabb7e19a53 341 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 71 327 9.7E-124 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 HVS_RS12665 a8499ac679ec73137201fcabb7e19a53 341 SUPERFAMILY SSF51569 1 337 1.1E-117 T 29-03-2018 HVS_RS00695 2baee41b6223aac59137c07fc03b67e8 144 Gene3D G3DSA:2.20.28.10 96 137 9.5E-4 T 29-03-2018 HVS_RS00695 2baee41b6223aac59137c07fc03b67e8 144 SUPERFAMILY SSF88659 34 78 2.01E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00695 2baee41b6223aac59137c07fc03b67e8 144 Gene3D G3DSA:3.30.1190.10 57 84 0.0016 T 29-03-2018 HVS_RS00695 2baee41b6223aac59137c07fc03b67e8 144 Hamap MF_00674 UPF0251 protein . 2 98 24.519 T 29-03-2018 IPR002852 Uncharacterised protein family UPF0251 HVS_RS00695 2baee41b6223aac59137c07fc03b67e8 144 Pfam PF02001 Protein of unknown function DUF134 3 95 1.2E-20 T 29-03-2018 IPR002852 Uncharacterised protein family UPF0251 HVS_RS00695 2baee41b6223aac59137c07fc03b67e8 144 Gene3D G3DSA:1.10.10.60 22 56 2.5E-4 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 SUPERFAMILY SSF81665 67 120 3.01E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 SUPERFAMILY SSF81665 217 311 3.01E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 SUPERFAMILY SSF56784 374 613 5.82E-57 T 29-03-2018 IPR023214 HAD-like domain HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 SUPERFAMILY SSF56784 316 336 5.82E-57 T 29-03-2018 IPR023214 HAD-like domain HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 433 444 1.4E-22 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 318 332 1.4E-22 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 456 466 1.4E-22 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 1.4E-22 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 531 1.4E-22 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 548 1.4E-22 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 Gene3D G3DSA:1.20.1110.10 466 615 5.6E-24 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 SUPERFAMILY SSF81653 119 216 1.28E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 Gene3D G3DSA:1.20.1110.10 15 331 1.3E-34 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 Pfam PF00122 E1-E2 ATPase 117 298 2.8E-49 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00941 Cadmium-transporting ATPase signature 201 215 3.3E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00941 Cadmium-transporting ATPase signature 101 121 3.3E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 PRINTS PR00941 Cadmium-transporting ATPase signature 182 198 3.3E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 67 617 3.0E-157 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 67 614 2.1E-172 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 592 5.1E-73 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 Gene3D G3DSA:3.40.1110.10 332 465 2.0E-31 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 Pfam PF00702 haloacid dehalogenase-like hydrolase 316 526 2.2E-31 T 29-03-2018 HVS_RS03735 3b4c99ee8c83903acaad54c1d065fe0a 620 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 320 326 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HVS_RS02915 bf9241e937275a2ca5567ccf6acebe7a 144 Pfam PF03965 Penicillinase repressor 24 138 1.1E-31 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HVS_RS02915 bf9241e937275a2ca5567ccf6acebe7a 144 SUPERFAMILY SSF46785 21 140 4.91E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02915 bf9241e937275a2ca5567ccf6acebe7a 144 Gene3D G3DSA:1.10.10.10 25 87 6.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02915 bf9241e937275a2ca5567ccf6acebe7a 144 PIRSF PIRSF019455 16 144 6.4E-37 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HVS_RS02915 bf9241e937275a2ca5567ccf6acebe7a 144 Gene3D G3DSA:1.10.4040.10 89 138 5.4E-15 T 29-03-2018 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 PIRSF PIRSF000098 1 415 1.2E-138 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 SUPERFAMILY SSF51735 1 153 3.54E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 Gene3D G3DSA:3.40.50.720 1 143 1.1E-28 T 29-03-2018 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 124 2.8E-15 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 178 200 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 Gene3D G3DSA:3.30.360.10 144 294 5.7E-57 T 29-03-2018 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 Pfam PF00742 Homoserine dehydrogenase 132 310 1.2E-65 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 HVS_RS12195 3ce056ea9e2059e77868218156227dbd 418 SUPERFAMILY SSF55347 132 297 4.64E-51 T 29-03-2018 HVS_RS05275 239a40ad34aa91b457d427365ccbf105 258 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 251 1.2E-83 T 29-03-2018 IPR005226 UPF0014 family HVS_RS05275 239a40ad34aa91b457d427365ccbf105 258 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 12 257 1.1E-55 T 29-03-2018 IPR005226 UPF0014 family HVS_RS09235 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS06105 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS02745 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS02840 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS14720 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS11325 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS03625 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS06535 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS13015 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS06780 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS11795 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS14890 4cf4a5fadba6a94b3a5860aeabe20b00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.3E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 SUPERFAMILY SSF49384 32 179 1.28E-49 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 SUPERFAMILY SSF49384 514 620 2.88E-34 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 SUPERFAMILY SSF49384 353 501 7.07E-51 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 SUPERFAMILY SSF49384 192 340 5.76E-51 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Gene3D G3DSA:2.60.40.680 514 621 5.6E-26 T 29-03-2018 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Gene3D G3DSA:2.60.40.680 192 346 4.1E-44 T 29-03-2018 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Gene3D G3DSA:2.60.40.680 32 185 4.8E-42 T 29-03-2018 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Gene3D G3DSA:2.60.40.680 353 507 5.8E-44 T 29-03-2018 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Pfam PF00963 Cohesin domain 33 184 5.3E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Pfam PF00963 Cohesin domain 516 620 6.9E-21 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Pfam PF00963 Cohesin domain 194 345 3.2E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02500 0ef6734be1a9687fcda4293649860c54 621 Pfam PF00963 Cohesin domain 355 506 9.9E-29 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 SUPERFAMILY SSF55973 121 243 1.06E-55 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.7E-44 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Pfam PF02772 S-adenosylmethionine synthetase, central domain 126 242 7.9E-52 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 SUPERFAMILY SSF55973 4 109 2.94E-48 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 SUPERFAMILY SSF55973 244 392 1.6E-70 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 392 1.5E-189 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 394 60.509 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Gene3D G3DSA:3.30.300.10 257 396 1.1E-49 T 29-03-2018 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 PIRSF PIRSF000497 1 395 1.9E-180 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 244 383 3.4E-71 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Gene3D G3DSA:3.30.300.10 11 143 2.0E-46 T 29-03-2018 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 Gene3D G3DSA:3.30.300.10 144 244 4.4E-50 T 29-03-2018 HVS_RS01335 cdd6c347943eca334e91b70f6608377c 397 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 270 278 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 Gene3D G3DSA:1.10.3120.10 213 400 2.0E-50 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 423 1.1E-37 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 SUPERFAMILY SSF102735 1 131 1.18E-39 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 TIGRFAM TIGR00115 tig: trigger factor 13 422 9.1E-137 T 29-03-2018 IPR005215 Trigger factor GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 Gene3D G3DSA:3.30.70.1050 1 119 6.8E-37 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 Hamap MF_00303 Trigger factor [tig]. 1 428 23.36 T 29-03-2018 IPR005215 Trigger factor GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 SUPERFAMILY SSF54534 89 244 1.83E-34 T 29-03-2018 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 237 4.1E-13 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 SUPERFAMILY SSF109998 250 428 7.98E-42 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 1.7E-44 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HVS_RS12890 7b20f8f0e25cbd5f705eea44fa4057ec 428 PIRSF PIRSF003095 1 428 5.9E-131 T 29-03-2018 IPR005215 Trigger factor GO:0015031 HVS_RS02240 b73fd5fa727940a1908a8fc3544e71f2 214 Gene3D G3DSA:3.40.50.360 1 212 4.3E-29 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS02240 b73fd5fa727940a1908a8fc3544e71f2 214 Pfam PF02525 Flavodoxin-like fold 2 203 4.9E-29 T 29-03-2018 IPR003680 Flavodoxin-like fold HVS_RS02240 b73fd5fa727940a1908a8fc3544e71f2 214 SUPERFAMILY SSF52218 1 212 1.52E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS02240 b73fd5fa727940a1908a8fc3544e71f2 214 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 210 20.2 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82866 290 487 1.31E-47 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82693 134 181 4.19E-15 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82693 267 321 4.19E-15 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Gene3D G3DSA:3.30.70.1430 560 661 2.4E-24 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Gene3D G3DSA:3.30.2090.10 180 266 1.8E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82693 559 658 8.89E-17 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 617 631 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 2.0E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82714 183 265 4.45E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82714 716 797 1.06E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Pfam PF00873 AcrB/AcrD/AcrF family 3 1016 3.8E-273 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82866 795 1019 4.05E-57 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 SUPERFAMILY SSF82693 42 134 2.17E-25 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Gene3D G3DSA:3.30.70.1430 41 140 9.3E-27 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Gene3D G3DSA:1.20.1640.10 267 489 5.2E-51 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Gene3D G3DSA:1.20.1640.10 801 1018 9.3E-48 T 29-03-2018 HVS_RS05910 5cfde2456b8be564b49147097e55c2cc 1034 Gene3D G3DSA:3.30.2090.10 713 799 2.7E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains HVS_RS03355 464e5cd0a179595d3eab7143bc4a82e9 502 Pfam PF04055 Radical SAM superfamily 178 351 8.5E-22 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS03355 464e5cd0a179595d3eab7143bc4a82e9 502 Gene3D G3DSA:3.20.20.70 118 491 4.4E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS03355 464e5cd0a179595d3eab7143bc4a82e9 502 SUPERFAMILY SSF102114 169 479 4.71E-69 T 29-03-2018 HVS_RS03355 464e5cd0a179595d3eab7143bc4a82e9 502 SMART SM00729 170 392 2.0E-45 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS03355 464e5cd0a179595d3eab7143bc4a82e9 502 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 88 485 3.8E-167 T 29-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ HVS_RS10600 f45931e257dffff1e98d702550c54bd1 293 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 88 274 7.9E-20 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS10600 f45931e257dffff1e98d702550c54bd1 293 Gene3D G3DSA:3.40.50.1110 19 288 2.2E-23 T 29-03-2018 HVS_RS10600 f45931e257dffff1e98d702550c54bd1 293 SUPERFAMILY SSF52266 80 285 1.35E-27 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 SUPERFAMILY SSF81333 47 116 7.19E-17 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 ProSitePatterns PS00605 ATP synthase c subunit signature. 80 101 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 PRINTS PR00124 ATP synthase C subunit signature 52 71 4.1E-13 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 PRINTS PR00124 ATP synthase C subunit signature 73 88 4.1E-13 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 PRINTS PR00124 ATP synthase C subunit signature 90 115 4.1E-13 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 Pfam PF00137 ATP synthase subunit C 51 114 6.0E-13 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 Hamap MF_01396 ATP synthase subunit c [atpH]. 50 115 12.579 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 61 116 1.1E-12 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HVS_RS03635 41b3a5a8a150553b36a83c50342ddce5 118 Gene3D G3DSA:1.20.20.10 45 117 1.8E-17 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS08560 409bd5fb286ca1766e34a335a565ddeb 83 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 72 0.004 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HVS_RS08560 409bd5fb286ca1766e34a335a565ddeb 83 SUPERFAMILY SSF47336 2 75 4.84E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS08560 409bd5fb286ca1766e34a335a565ddeb 83 Hamap MF_01217 Acyl carrier protein [acpP]. 1 75 15.426 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HVS_RS08560 409bd5fb286ca1766e34a335a565ddeb 83 Pfam PF00550 Phosphopantetheine attachment site 4 71 1.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS08560 409bd5fb286ca1766e34a335a565ddeb 83 Gene3D G3DSA:1.10.1200.10 1 77 1.3E-18 T 29-03-2018 HVS_RS11490 8e7ea8550b27ba34fbcab9109149decd 378 Pfam PF10646 Sporulation and spore germination 99 210 3.5E-21 T 29-03-2018 IPR019606 GerMN domain HVS_RS11490 8e7ea8550b27ba34fbcab9109149decd 378 Pfam PF10646 Sporulation and spore germination 246 356 1.5E-13 T 29-03-2018 IPR019606 GerMN domain HVS_RS11490 8e7ea8550b27ba34fbcab9109149decd 378 SMART SM00909 122 214 9.0E-21 T 29-03-2018 IPR019606 GerMN domain HVS_RS11490 8e7ea8550b27ba34fbcab9109149decd 378 SMART SM00909 275 361 2.6E-13 T 29-03-2018 IPR019606 GerMN domain HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 295 1.9E-36 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 Pfam PF13361 UvrD-like helicase C-terminal domain 632 738 3.9E-18 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 Gene3D G3DSA:3.40.50.300 302 767 3.8E-40 T 29-03-2018 HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 SUPERFAMILY SSF52540 564 672 1.48E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 SUPERFAMILY SSF52540 714 761 1.48E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 SUPERFAMILY SSF52540 2 469 1.48E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11405 748f79cfd4916d6bb093917ef55ca401 767 Gene3D G3DSA:3.40.50.300 1 301 6.6E-33 T 29-03-2018 HVS_RS10365 9cc9e28b00bd9a7287a209a577b3cfc2 357 Gene3D G3DSA:3.40.50.2300 211 290 0.13 T 29-03-2018 HVS_RS10365 9cc9e28b00bd9a7287a209a577b3cfc2 357 SUPERFAMILY SSF52540 201 266 1.77E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10365 9cc9e28b00bd9a7287a209a577b3cfc2 357 SUPERFAMILY SSF52540 32 75 1.77E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10365 9cc9e28b00bd9a7287a209a577b3cfc2 357 SUPERFAMILY SSF52540 121 158 1.04E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10365 9cc9e28b00bd9a7287a209a577b3cfc2 357 SUPERFAMILY SSF52540 22 69 1.04E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10365 9cc9e28b00bd9a7287a209a577b3cfc2 357 Gene3D G3DSA:3.40.50.300 35 200 4.7E-5 T 29-03-2018 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Pfam PF13155 Toprim-like 259 343 1.2E-20 T 29-03-2018 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Gene3D G3DSA:3.40.1360.10 240 362 2.6E-33 T 29-03-2018 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Pfam PF01807 CHC2 zinc finger 7 98 5.3E-35 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 TIGRFAM TIGR01391 dnaG: DNA primase 6 411 4.0E-144 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 SMART SM00493 256 327 1.8E-17 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 SMART SM00400 36 90 3.2E-28 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 SUPERFAMILY SSF56731 115 419 2.35E-103 T 29-03-2018 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Gene3D G3DSA:3.90.980.10 108 239 1.4E-46 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Hamap MF_00974 DNA primase [dnaG]. 4 590 28.161 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 SUPERFAMILY SSF48024 457 524 4.18E-5 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Pfam PF10410 DnaB-helicase binding domain of primase 363 418 4.3E-13 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 SUPERFAMILY SSF57783 5 99 6.46E-34 T 29-03-2018 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 250 9.3E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Gene3D G3DSA:3.90.580.10 1 103 3.3E-33 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Gene3D G3DSA:1.10.860.10 459 552 4.0E-6 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 PIRSF PIRSF002811 2 596 1.2E-169 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HVS_RS09290 fd58c086a41fdd09d8655a70d33ff3d8 596 Gene3D G3DSA:1.20.50.20 363 415 1.1E-6 T 29-03-2018 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Gene3D G3DSA:2.40.30.10 282 395 2.5E-31 T 29-03-2018 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Pfam PF03144 Elongation factor Tu domain 2 318 385 3.3E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SUPERFAMILY SSF54211 476 592 8.09E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SUPERFAMILY SSF50447 259 396 1.54E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Gene3D G3DSA:3.40.50.300 1 281 7.8E-49 T 29-03-2018 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 154 7.6E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 4 686 5.9E-231 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SUPERFAMILY SSF52540 5 276 5.04E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Pfam PF00009 Elongation factor Tu GTP binding domain 8 275 4.4E-45 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SUPERFAMILY SSF54980 596 685 3.17E-28 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SUPERFAMILY SSF54980 398 476 7.91E-22 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Gene3D G3DSA:3.30.230.10 487 601 9.1E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Gene3D G3DSA:3.30.70.240 602 680 1.6E-27 T 29-03-2018 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Pfam PF00679 Elongation factor G C-terminus 593 680 5.6E-29 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SMART SM00889 474 591 1.7E-70 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 SMART SM00838 593 681 1.6E-41 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Pfam PF03764 Elongation factor G, domain IV 473 590 9.7E-45 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 PRINTS PR00315 GTP-binding elongation factor signature 129 138 1.7E-8 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 PRINTS PR00315 GTP-binding elongation factor signature 77 87 1.7E-8 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 PRINTS PR00315 GTP-binding elongation factor signature 93 104 1.7E-8 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.7E-8 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Gene3D G3DSA:3.30.70.870 396 486 4.7E-30 T 29-03-2018 HVS_RS12660 b7d5cf6d3d63ad70955c5b56bc4f604c 693 Pfam PF14492 Elongation Factor G, domain II 398 471 2.6E-30 T 29-03-2018 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 Gene3D G3DSA:3.50.50.60 1 315 1.6E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 143 1.6E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 3.2E-7 T 29-03-2018 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.2E-7 T 29-03-2018 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 246 261 3.2E-7 T 29-03-2018 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 SUPERFAMILY SSF51905 2 154 2.91E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13860 45e1c82d50f92d41c2c7c18cdcce0386 356 SUPERFAMILY SSF51905 241 292 2.91E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 Pfam PF05193 Peptidase M16 inactive domain 165 341 8.2E-42 T 29-03-2018 IPR007863 Peptidase M16, C-terminal HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 SUPERFAMILY SSF63411 4 205 7.81E-61 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 Gene3D G3DSA:3.30.830.10 1 225 9.7E-62 T 29-03-2018 HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 SUPERFAMILY SSF63411 218 409 2.23E-44 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 1.6E-45 T 29-03-2018 IPR011765 Peptidase M16, N-terminal HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 HVS_RS10020 e2aff19f6636f2b9f45ae796d938aaae 417 Gene3D G3DSA:3.30.830.10 226 417 3.8E-41 T 29-03-2018 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Gene3D G3DSA:2.60.120.260 561 710 6.3E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 SUPERFAMILY SSF63446 725 794 4.19E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Gene3D G3DSA:1.10.1330.10 723 795 4.9E-9 T 29-03-2018 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Pfam PF00756 Putative esterase 847 988 4.8E-6 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 764 783 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 SUPERFAMILY SSF51445 196 543 8.44E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 SUPERFAMILY SSF53474 836 1085 9.3E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 454 464 - T 29-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Pfam PF00331 Glycosyl hydrolase family 10 196 537 2.1E-100 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Gene3D G3DSA:3.20.20.80 192 551 3.4E-59 T 29-03-2018 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 SMART SM00633 237 540 3.8E-104 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Gene3D G3DSA:3.40.50.1820 811 1087 8.9E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 SUPERFAMILY SSF49785 33 180 2.34E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Gene3D G3DSA:2.60.120.260 32 189 6.4E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 PRINTS PR00134 Glycosyl hydrolase family 10 signature 417 429 2.2E-12 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 PRINTS PR00134 Glycosyl hydrolase family 10 signature 274 286 2.2E-12 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 PRINTS PR00134 Glycosyl hydrolase family 10 signature 390 401 2.2E-12 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 PRINTS PR00134 Glycosyl hydrolase family 10 signature 330 341 2.2E-12 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 SUPERFAMILY SSF49785 565 710 7.65E-36 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Pfam PF02018 Carbohydrate binding domain 566 697 1.3E-16 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Pfam PF02018 Carbohydrate binding domain 35 163 8.8E-13 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS04815 7d964a8709f66cf219748ad501b475e4 1088 Pfam PF00404 Dockerin type I repeat 764 784 5.3E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 SUPERFAMILY SSF55073 133 241 1.18E-18 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 235 1.1E-13 T 29-03-2018 IPR000160 GGDEF domain HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 Pfam PF00072 Response regulator receiver domain 6 117 9.8E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 Gene3D G3DSA:3.40.50.2300 2 124 1.6E-39 T 29-03-2018 HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 SUPERFAMILY SSF52172 3 147 2.7E-43 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 SMART SM00267 114 303 4.9E-7 T 29-03-2018 IPR000160 GGDEF domain HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 Gene3D G3DSA:3.30.70.270 125 304 2.4E-22 T 29-03-2018 HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 142 225 3.2E-14 T 29-03-2018 IPR000160 GGDEF domain HVS_RS14275 ab93e8dc68577f0fdca97746369f9603 310 SMART SM00448 4 117 2.1E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 SUPERFAMILY SSF46955 2 112 1.61E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 Gene3D G3DSA:1.10.1660.10 58 133 1.1E-5 T 29-03-2018 HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 Gene3D G3DSA:1.10.1660.10 1 57 8.8E-20 T 29-03-2018 HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 SMART SM00422 2 72 1.7E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 Pfam PF13411 MerR HTH family regulatory protein 3 68 1.0E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 Gene3D G3DSA:3.20.80.10 134 276 9.7E-27 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 Pfam PF06445 GyrI-like small molecule binding domain 129 275 3.0E-12 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 SMART SM00871 128 275 1.0E-17 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding HVS_RS09055 5e45430f892c7c6f053be4e43387aeb3 277 SUPERFAMILY SSF55136 129 277 8.02E-19 T 29-03-2018 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 Gene3D G3DSA:1.20.5.1150 16 52 1.2E-18 T 29-03-2018 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.289 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 58 6.1E-24 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 Pfam PF01165 Ribosomal protein S21 4 57 3.0E-23 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 6.0E-8 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.3E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.3E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.3E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11190 f3576b805ce3028c0e3c990cf910d967 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.3E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 SUPERFAMILY SSF55120 1 228 1.06E-81 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 171 229 4.9E-16 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 Gene3D G3DSA:2.30.130.10 231 294 2.7E-4 T 29-03-2018 IPR002478 PUA domain GO:0003723 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 208 9.0E-77 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 Gene3D G3DSA:3.30.2350.10 1 220 6.6E-85 T 29-03-2018 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 170 2.4E-60 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 HVS_RS10505 3cbc37d9dc8aa9007df33847c902d693 294 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 293 19.368 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS03075 0214bca4165b5b2dd06b81647e60b5a8 307 SMART SM00382 30 214 7.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS03075 0214bca4165b5b2dd06b81647e60b5a8 307 SUPERFAMILY SSF52540 3 224 1.78E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03075 0214bca4165b5b2dd06b81647e60b5a8 307 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS03075 0214bca4165b5b2dd06b81647e60b5a8 307 Gene3D G3DSA:3.40.50.300 1 249 8.2E-56 T 29-03-2018 HVS_RS03075 0214bca4165b5b2dd06b81647e60b5a8 307 Pfam PF00005 ABC transporter 21 162 1.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS11530 40a1ad509ee3aa9366344a04e71374d6 383 SUPERFAMILY SSF88713 111 287 6.3E-22 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HVS_RS11530 40a1ad509ee3aa9366344a04e71374d6 383 Gene3D G3DSA:3.20.20.370 87 369 4.3E-26 T 29-03-2018 HVS_RS11530 40a1ad509ee3aa9366344a04e71374d6 383 Pfam PF01522 Polysaccharide deacetylase 150 282 5.2E-14 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Gene3D G3DSA:2.40.240.10 477 563 1.5E-34 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Gene3D G3DSA:1.10.1160.10 272 349 1.9E-35 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Gene3D G3DSA:2.40.240.10 355 476 1.2E-51 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 71 84 2.9E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 54 2.9E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 221 231 2.9E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Gene3D G3DSA:3.40.50.620 34 174 4.5E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 SUPERFAMILY SSF50715 351 563 1.78E-77 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 351 544 4.1E-64 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 SUPERFAMILY SSF52374 21 348 3.1E-105 T 29-03-2018 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 39 348 2.9E-117 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 565 52.51 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 39 567 1.5E-236 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 HVS_RS07580 09a22fff183a7803ea0a2526b8cfeb72 573 Gene3D G3DSA:3.40.50.620 175 271 6.1E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 Gene3D G3DSA:1.20.1270.60 60 245 4.3E-4 T 29-03-2018 HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 407 569 1.5E-52 T 29-03-2018 IPR000160 GGDEF domain HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 Pfam PF00990 Diguanylate cyclase, GGDEF domain 409 565 1.8E-46 T 29-03-2018 IPR000160 GGDEF domain HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 Gene3D G3DSA:3.30.450.40 246 403 4.3E-13 T 29-03-2018 IPR029016 GAF domain-like HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 Gene3D G3DSA:3.30.70.270 404 577 3.9E-54 T 29-03-2018 HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 SUPERFAMILY SSF55781 235 408 3.93E-17 T 29-03-2018 IPR029016 GAF domain-like HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 SMART SM00267 398 570 1.3E-55 T 29-03-2018 IPR000160 GGDEF domain HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 SMART SM00065 251 406 0.0011 T 29-03-2018 IPR003018 GAF domain GO:0005515 HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 SUPERFAMILY SSF55073 414 568 5.49E-48 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS10890 476802fa2769f1cbb1c4ecbc43d57725 578 Pfam PF01590 GAF domain 251 396 6.5E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 363 34.595 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 358 5.3E-98 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 SUPERFAMILY SSF53756 2 364 6.7E-109 T 29-03-2018 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 354 2.6E-41 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 ProSitePatterns PS00221 MIP family signature. 13 21 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 Gene3D G3DSA:3.40.50.2000 178 347 2.6E-32 T 29-03-2018 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 143 4.5E-41 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10430 8b6d3d1e10bacf22e876c6483d024fed 366 Gene3D G3DSA:3.40.50.2000 1 177 5.6E-38 T 29-03-2018 HVS_RS15310 6156f708489067c531424242bcaf7166 677 SUPERFAMILY SSF55383 53 137 1.01E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15310 6156f708489067c531424242bcaf7166 677 Pfam PF00144 Beta-lactamase 157 469 1.4E-60 T 29-03-2018 IPR001466 Beta-lactamase-related HVS_RS15310 6156f708489067c531424242bcaf7166 677 SUPERFAMILY SSF56601 153 477 1.55E-82 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS15310 6156f708489067c531424242bcaf7166 677 Gene3D G3DSA:3.40.710.10 147 488 1.2E-77 T 29-03-2018 HVS_RS15310 6156f708489067c531424242bcaf7166 677 Pfam PF07833 Copper amine oxidase N-terminal domain 51 142 3.7E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15310 6156f708489067c531424242bcaf7166 677 Gene3D G3DSA:3.30.457.10 59 123 6.3E-29 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15310 6156f708489067c531424242bcaf7166 677 Gene3D G3DSA:3.30.457.10 124 146 3.7E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15310 6156f708489067c531424242bcaf7166 677 Gene3D G3DSA:3.30.457.10 13 58 0.0068 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15310 6156f708489067c531424242bcaf7166 677 Pfam PF11954 Domain of unknown function (DUF3471) 491 575 2.4E-11 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal HVS_RS15310 6156f708489067c531424242bcaf7166 677 Pfam PF11954 Domain of unknown function (DUF3471) 590 667 3.0E-10 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 SUPERFAMILY SSF47060 3 87 9.71E-37 T 29-03-2018 IPR009068 S15/NS1, RNA-binding HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 SMART SM01387 6 86 2.6E-55 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 87 23.066 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 ProSitePatterns PS00362 Ribosomal protein S15 signature. 37 67 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 8 86 3.0E-33 T 29-03-2018 HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 3 87 2.0E-40 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 Pfam PF00312 Ribosomal protein S15 6 86 9.9E-39 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS10030 8f9e5e5a3d45d216bc2b452e23f6ac6c 87 Gene3D G3DSA:1.10.287.10 1 87 1.9E-35 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 SUPERFAMILY SSF51905 2 186 2.76E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 Gene3D G3DSA:3.50.50.60 95 210 5.0E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 Gene3D G3DSA:3.50.50.60 211 253 0.042 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 275 8.0E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 Gene3D G3DSA:3.50.50.60 7 94 6.7E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 Gene3D G3DSA:3.50.50.60 254 358 5.6E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 SUPERFAMILY SSF51905 143 307 8.01E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 1.1E-14 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 1.1E-14 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.1E-14 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.1E-14 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.0E-21 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 3.0E-21 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 3.0E-21 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 3.0E-21 T 29-03-2018 HVS_RS01770 e5a06483f147b13c737417e63feb0cd7 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.0E-21 T 29-03-2018 HVS_RS11445 925fa089070328403304260cce7a54fa 130 Gene3D G3DSA:3.40.30.10 30 129 1.8E-17 T 29-03-2018 HVS_RS11445 925fa089070328403304260cce7a54fa 130 SUPERFAMILY SSF52833 32 123 1.23E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 SUPERFAMILY SSF52540 181 445 1.24E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 Gene3D G3DSA:3.40.50.300 247 448 4.1E-37 T 29-03-2018 HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 30 656 7.8E-230 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 SUPERFAMILY SSF52540 384 589 3.36E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 Gene3D G3DSA:2.40.50.140 49 147 3.2E-17 T 29-03-2018 HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 SMART SM00487 261 451 2.4E-35 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 SMART SM00490 496 581 6.5E-22 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 Pfam PF17191 RecG wedge domain 15 172 3.8E-31 T 29-03-2018 IPR033454 RecG, wedge domain HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 Pfam PF00270 DEAD/DEAH box helicase 267 425 1.1E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 Gene3D G3DSA:3.40.50.300 449 621 2.9E-32 T 29-03-2018 HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 Pfam PF00271 Helicase conserved C-terminal domain 465 580 5.0E-18 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS10880 8e023f2b1ac119083a774f5d352d59e6 692 SUPERFAMILY SSF50249 11 176 1.41E-46 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS00215 8a8da0e88a6aec16164e5d7c1e0b95ae 369 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 203 350 7.2E-15 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 HVS_RS00215 8a8da0e88a6aec16164e5d7c1e0b95ae 369 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 14 179 1.7E-39 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 HVS_RS00215 8a8da0e88a6aec16164e5d7c1e0b95ae 369 SUPERFAMILY SSF53756 91 368 4.28E-30 T 29-03-2018 HVS_RS00215 8a8da0e88a6aec16164e5d7c1e0b95ae 369 Gene3D G3DSA:3.40.50.2000 170 363 3.5E-25 T 29-03-2018 HVS_RS05780 4ad21cadab89252fa627ec2c2d7fbfe7 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 4.1E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS05780 4ad21cadab89252fa627ec2c2d7fbfe7 96 Gene3D G3DSA:1.10.287.850 1 93 5.3E-17 T 29-03-2018 HVS_RS05780 4ad21cadab89252fa627ec2c2d7fbfe7 96 SUPERFAMILY SSF140453 3 95 6.28E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS05780 4ad21cadab89252fa627ec2c2d7fbfe7 96 Pfam PF06013 Proteins of 100 residues with WXG 4 85 4.9E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS11760 b085d34798ab98c003e11cb160ad9ac9 190 Pfam PF13563 2'-5' RNA ligase superfamily 32 168 3.7E-14 T 29-03-2018 HVS_RS11760 b085d34798ab98c003e11cb160ad9ac9 190 Gene3D G3DSA:3.90.1140.10 3 186 3.4E-30 T 29-03-2018 HVS_RS11760 b085d34798ab98c003e11cb160ad9ac9 190 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 3 184 2.1E-43 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HVS_RS11760 b085d34798ab98c003e11cb160ad9ac9 190 SUPERFAMILY SSF55144 3 184 2.09E-36 T 29-03-2018 IPR009097 Cyclic phosphodiesterase HVS_RS11760 b085d34798ab98c003e11cb160ad9ac9 190 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 184 22.796 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 HVS_RS15460 80703de9e1ef44a1e946b2ff9eaf1cf6 234 Pfam PF00041 Fibronectin type III domain 75 147 1.8E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15460 80703de9e1ef44a1e946b2ff9eaf1cf6 234 SUPERFAMILY SSF63446 1 70 3.92E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS15460 80703de9e1ef44a1e946b2ff9eaf1cf6 234 SUPERFAMILY SSF49265 74 157 8.41E-13 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15460 80703de9e1ef44a1e946b2ff9eaf1cf6 234 SMART SM00060 74 149 2.8E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15460 80703de9e1ef44a1e946b2ff9eaf1cf6 234 Gene3D G3DSA:2.60.40.10 68 158 8.7E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15460 80703de9e1ef44a1e946b2ff9eaf1cf6 234 Gene3D G3DSA:1.10.1330.10 1 67 5.3E-4 T 29-03-2018 HVS_RS13225 f80b9c8da7b0a5b78085aed4f3c3d825 299 Pfam PF12224 Putative amidoligase enzyme 4 239 3.5E-68 T 29-03-2018 IPR022025 Putative amidoligase enzyme HVS_RS10315 505272676ad21b679feb0abe22f66582 257 Gene3D G3DSA:1.10.1270.10 172 257 3.9E-16 T 29-03-2018 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PRINTS PR00046 Major sigma-70 factor signature 210 222 3.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PRINTS PR00046 Major sigma-70 factor signature 227 242 3.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PRINTS PR00046 Major sigma-70 factor signature 90 98 3.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PRINTS PR00046 Major sigma-70 factor signature 242 253 3.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PRINTS PR00046 Major sigma-70 factor signature 66 79 3.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.3E-149 T 29-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 256 4.9E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 Pfam PF04542 Sigma-70 region 2 42 111 4.8E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 256 1.8E-83 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 Gene3D G3DSA:1.10.10.10 111 163 1.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PIRSF PIRSF000770 160 257 1.1E-13 T 29-03-2018 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PIRSF PIRSF000770 11 131 1.5E-19 T 29-03-2018 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 PIRSF PIRSF000770 120 157 0.18 T 29-03-2018 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 SUPERFAMILY SSF88659 175 257 1.72E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 SUPERFAMILY SSF88659 114 189 7.41E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 Pfam PF04545 Sigma-70, region 4 206 255 4.9E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 Pfam PF04539 Sigma-70 region 3 124 169 1.6E-9 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 SUPERFAMILY SSF88946 6 110 3.53E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10315 505272676ad21b679feb0abe22f66582 257 Gene3D G3DSA:1.10.601.10 10 110 1.4E-33 T 29-03-2018 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 ProSitePatterns PS01244 Aconitase family signature 2. 362 375 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 PRINTS PR00415 Aconitase family signature 128 143 2.2E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 PRINTS PR00415 Aconitase family signature 362 375 2.2E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 PRINTS PR00415 Aconitase family signature 204 217 2.2E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 PRINTS PR00415 Aconitase family signature 306 317 2.2E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 PRINTS PR00415 Aconitase family signature 114 127 2.2E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 PRINTS PR00415 Aconitase family signature 190 203 2.2E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 5 428 42.912 T 29-03-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 6 425 5.1E-136 T 29-03-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 6 425 1.7E-155 T 29-03-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 SUPERFAMILY SSF53732 4 428 3.27E-143 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 Gene3D G3DSA:3.30.499.10 1 149 4.8E-32 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 Gene3D G3DSA:3.30.499.10 286 431 3.1E-52 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 Gene3D G3DSA:3.40.1060.10 150 282 1.3E-43 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 ProSitePatterns PS00450 Aconitase family signature 1. 302 318 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 HVS_RS03345 60b2eae30a5494f9f0f3501cd8728d89 433 Pfam PF00330 Aconitase family (aconitate hydratase) 9 420 2.8E-107 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 SMART SM00562 1 134 3.5E-72 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 30.476 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 Pfam PF00334 Nucleoside diphosphate kinase 2 133 8.6E-53 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 8.5E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 8.5E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 8.5E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 8.5E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 8.5E-42 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 Gene3D G3DSA:3.30.70.141 1 135 1.6E-51 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS08065 95adad128e60ed44474c7816575e5817 136 SUPERFAMILY SSF54919 1 134 2.23E-55 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS00520 80dba993627fcf17ff86a15ede47a83f 103 Pfam PF04026 SpoVG 1 81 6.0E-39 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 HVS_RS00520 80dba993627fcf17ff86a15ede47a83f 103 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 98 28.499 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 HVS_RS00520 80dba993627fcf17ff86a15ede47a83f 103 Gene3D G3DSA:3.30.1120.40 1 82 1.3E-37 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 HVS_RS00520 80dba993627fcf17ff86a15ede47a83f 103 SUPERFAMILY SSF160537 1 82 4.19E-34 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 HVS_RS13395 a8a91727095fb63052633ff12d9d469e 510 Pfam PF01943 Polysaccharide biosynthesis protein 8 290 6.3E-19 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 SUPERFAMILY SSF56042 167 337 2.84E-59 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 SUPERFAMILY SSF55326 2 166 2.09E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 Gene3D G3DSA:3.30.1330.10 31 157 8.4E-56 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 Gene3D G3DSA:3.90.650.10 167 339 6.5E-64 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 172 334 1.1E-34 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 3 332 8.6E-141 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 70 160 1.4E-18 T 29-03-2018 IPR016188 PurM-like, N-terminal domain HVS_RS06230 44ca5e35cf9ca2230366ee63b54563f2 340 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 339 47.865 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS01795 5b5e2c97012367c3d011b44d0470b152 230 Pfam PF07486 Cell Wall Hydrolase 131 228 3.3E-31 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HVS_RS01795 5b5e2c97012367c3d011b44d0470b152 230 SUPERFAMILY SSF47090 42 105 5.89E-22 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01795 5b5e2c97012367c3d011b44d0470b152 230 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 39 230 1.7E-93 T 29-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 HVS_RS01795 5b5e2c97012367c3d011b44d0470b152 230 Gene3D G3DSA:1.10.101.10 33 112 1.5E-22 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01795 5b5e2c97012367c3d011b44d0470b152 230 Pfam PF01471 Putative peptidoglycan binding domain 47 102 1.4E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS00490 962e78454ab293fd93ea950e122f24f9 258 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 142 1.4E-28 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HVS_RS00490 962e78454ab293fd93ea950e122f24f9 258 Pfam PF00460 Flagella basal body rod protein 13 35 1.2E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HVS_RS00490 962e78454ab293fd93ea950e122f24f9 258 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 252 6.2E-21 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HVS_RS00490 962e78454ab293fd93ea950e122f24f9 258 SUPERFAMILY SSF117143 92 215 2.62E-17 T 29-03-2018 HVS_RS05470 29fbe9779b7e401b15d1e812fd8d9da8 293 SUPERFAMILY SSF111331 1 292 3.92E-64 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain HVS_RS05470 29fbe9779b7e401b15d1e812fd8d9da8 293 SMART SM00046 3 123 2.1E-7 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HVS_RS05470 29fbe9779b7e401b15d1e812fd8d9da8 293 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 290 5.9E-53 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase HVS_RS05470 29fbe9779b7e401b15d1e812fd8d9da8 293 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 124 1.6E-22 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HVS_RS05470 29fbe9779b7e401b15d1e812fd8d9da8 293 Gene3D G3DSA:3.40.50.10330 1 131 3.0E-20 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Gene3D G3DSA:3.80.10.10 110 210 8.3E-19 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Pfam PF12799 Leucine Rich repeats (2 copies) 207 246 1.4E-8 T 29-03-2018 IPR025875 Leucine rich repeat 4 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Pfam PF12799 Leucine Rich repeats (2 copies) 162 203 9.7E-11 T 29-03-2018 IPR025875 Leucine rich repeat 4 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Pfam PF12799 Leucine Rich repeats (2 copies) 251 291 6.5E-7 T 29-03-2018 IPR025875 Leucine rich repeat 4 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Pfam PF12799 Leucine Rich repeats (2 copies) 316 357 5.4E-7 T 29-03-2018 IPR025875 Leucine rich repeat 4 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Gene3D G3DSA:3.80.10.10 254 406 1.1E-25 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00369 293 317 93.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00369 227 250 47.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00369 205 226 78.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00369 161 182 34.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00369 183 204 15.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00369 271 292 25.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SUPERFAMILY SSF52058 128 355 1.25E-50 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 Gene3D G3DSA:3.80.10.10 211 253 1.0E-13 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 315 336 60.0 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 205 226 53.0 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 271 292 0.034 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 139 160 690.0 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 183 204 3.1 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 293 314 25.0 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 161 182 15.0 T 29-03-2018 HVS_RS08595 22bcc487358d7e71f170cfcf98eaf80c 411 SMART SM00365 227 248 46.0 T 29-03-2018 HVS_RS16205 89fb9787cdd6bd6cd1981932db411657 44 Pfam PF00468 Ribosomal protein L34 1 44 3.8E-22 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS16205 89fb9787cdd6bd6cd1981932db411657 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 6.5E-20 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS16205 89fb9787cdd6bd6cd1981932db411657 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 26 4.0E-6 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS16205 89fb9787cdd6bd6cd1981932db411657 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 14.809 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS03080 962197f9564ffc53664649aa5b4ee25b 256 Pfam PF12730 ABC-2 family transporter protein 4 187 4.6E-15 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 30.156 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 SUPERFAMILY SSF46929 156 201 3.53E-9 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Gene3D G3DSA:1.10.150.20 119 156 0.26 T 29-03-2018 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Gene3D G3DSA:1.10.8.10 157 202 1.2E-12 T 29-03-2018 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Gene3D G3DSA:2.40.50.140 1 66 9.4E-24 T 29-03-2018 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 SUPERFAMILY SSF47781 66 135 7.51E-21 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Pfam PF01330 RuvA N terminal domain 1 62 2.7E-22 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Gene3D G3DSA:1.10.150.20 67 118 3.8E-15 T 29-03-2018 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 SUPERFAMILY SSF50249 1 63 1.2E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 SMART SM00278 108 127 0.015 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 SMART SM00278 73 92 1.1 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Pfam PF14520 Helix-hairpin-helix domain 72 130 2.9E-18 T 29-03-2018 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 199 1.4E-46 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HVS_RS11515 6823a6ab08a43999df0679c56829c282 202 Pfam PF07499 RuvA, C-terminal domain 156 199 1.6E-11 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 130 1.4E-29 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 SUPERFAMILY SSF53092 4 128 1.12E-27 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 SUPERFAMILY SSF55920 87 351 5.89E-80 T 29-03-2018 IPR000994 Peptidase M24 HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 Gene3D G3DSA:3.40.350.10 1 128 9.2E-31 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 Gene3D G3DSA:3.90.230.10 129 356 1.4E-80 T 29-03-2018 HVS_RS08695 658a34509f5287375f5b3183f818dc24 356 Pfam PF00557 Metallopeptidase family M24 138 339 2.6E-68 T 29-03-2018 IPR000994 Peptidase M24 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 SMART SM00606 374 510 5.8E-49 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 SMART SM00606 531 657 4.4E-47 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Gene3D G3DSA:1.10.1330.10 661 725 0.0014 T 29-03-2018 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Gene3D G3DSA:2.60.120.260 372 510 2.7E-33 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 SUPERFAMILY SSF49785 376 509 1.84E-29 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 SUPERFAMILY SSF75005 39 380 1.15E-57 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Pfam PF04616 Glycosyl hydrolases family 43 40 359 1.8E-32 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 SUPERFAMILY SSF63446 663 725 1.57E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 ProSitePatterns PS00018 EF-hand calcium-binding domain. 701 713 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 SUPERFAMILY SSF49785 533 657 7.65E-33 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Gene3D G3DSA:2.60.120.260 528 660 4.0E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Pfam PF03422 Carbohydrate binding module (family 6) 539 656 7.2E-32 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Pfam PF03422 Carbohydrate binding module (family 6) 382 509 7.0E-40 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS09045 916cb97b54da0c354e567a39b2a452f6 727 Gene3D G3DSA:2.115.10.20 32 371 1.7E-64 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 Gene3D G3DSA:2.60.120.260 82 220 9.1E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 Gene3D G3DSA:2.60.120.260 233 320 2.2E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 SUPERFAMILY SSF49785 84 217 3.23E-35 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 Pfam PF00395 S-layer homology domain 594 636 3.1E-5 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 Pfam PF00395 S-layer homology domain 437 474 4.2E-5 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 SMART SM00606 85 217 5.8E-43 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 Pfam PF03422 Carbohydrate binding module (family 6) 93 217 8.7E-35 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 Pfam PF03422 Carbohydrate binding module (family 6) 236 318 2.9E-7 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS14405 aa00e8629c60572cd09dd2de9a246b92 1276 SUPERFAMILY SSF49785 235 319 2.21E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07635 2e04cf0713b46b5109a210d7d9393beb 351 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 248 341 9.5E-25 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HVS_RS07635 2e04cf0713b46b5109a210d7d9393beb 351 Gene3D G3DSA:3.40.50.970 1 274 1.6E-56 T 29-03-2018 HVS_RS07635 2e04cf0713b46b5109a210d7d9393beb 351 SUPERFAMILY SSF52922 240 349 6.81E-26 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS07635 2e04cf0713b46b5109a210d7d9393beb 351 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 238 1.0E-53 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HVS_RS07635 2e04cf0713b46b5109a210d7d9393beb 351 SUPERFAMILY SSF52518 3 234 9.82E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS06975 181b13b215c34566650cbddfabcb6c2b 259 SUPERFAMILY SSF55383 28 78 6.8E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06975 181b13b215c34566650cbddfabcb6c2b 259 SUPERFAMILY SSF49384 122 258 4.97E-26 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS06975 181b13b215c34566650cbddfabcb6c2b 259 Gene3D G3DSA:3.30.457.10 19 74 6.2E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06975 181b13b215c34566650cbddfabcb6c2b 259 Gene3D G3DSA:2.60.40.680 114 259 4.9E-23 T 29-03-2018 HVS_RS06975 181b13b215c34566650cbddfabcb6c2b 259 Pfam PF07833 Copper amine oxidase N-terminal domain 23 83 2.5E-11 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06975 181b13b215c34566650cbddfabcb6c2b 259 Pfam PF00963 Cohesin domain 124 244 1.8E-19 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS05380 e527db07d80c0a7dbffd4f3db807a723 275 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 5 273 5.5E-44 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HVS_RS05380 e527db07d80c0a7dbffd4f3db807a723 275 Pfam PF04085 rod shape-determining protein MreC 122 271 1.7E-40 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HVS_RS05380 e527db07d80c0a7dbffd4f3db807a723 275 PIRSF PIRSF038471 1 275 3.4E-63 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 HVS_RS05380 e527db07d80c0a7dbffd4f3db807a723 275 Gene3D G3DSA:1.20.5.170 27 109 5.3E-4 T 29-03-2018 HVS_RS04900 12d01112e8a27e02a9068584cf0a45ad 249 Gene3D G3DSA:3.40.1280.10 86 245 7.4E-30 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS04900 12d01112e8a27e02a9068584cf0a45ad 249 Pfam PF00588 SpoU rRNA Methylase family 98 236 1.2E-26 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HVS_RS04900 12d01112e8a27e02a9068584cf0a45ad 249 SUPERFAMILY SSF75217 91 240 5.17E-31 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS04975 2eab1617d59991d72a6439e199a64ce3 240 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 4.7E-11 T 29-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal HVS_RS04975 2eab1617d59991d72a6439e199a64ce3 240 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 135 8.5E-10 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 HVS_RS13760 4b62d86e94aa822ae7d1666edb7315f7 228 SUPERFAMILY SSF52540 74 205 1.06E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13760 4b62d86e94aa822ae7d1666edb7315f7 228 Pfam PF01695 IstB-like ATP binding protein 47 223 7.0E-30 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS13760 4b62d86e94aa822ae7d1666edb7315f7 228 Gene3D G3DSA:3.40.50.300 41 223 8.4E-13 T 29-03-2018 HVS_RS13760 4b62d86e94aa822ae7d1666edb7315f7 228 PIRSF PIRSF003073 3 228 9.4E-42 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 SUPERFAMILY SSF142433 248 408 5.1E-54 T 29-03-2018 IPR008136 CinA, C-terminal HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 SMART SM00852 4 170 2.6E-45 T 29-03-2018 IPR001453 MoaB/Mog domain HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 PIRSF PIRSF006728 1 413 9.3E-158 T 29-03-2018 IPR008135 Competence-induced protein CinA HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 413 168.521 T 29-03-2018 IPR008135 Competence-induced protein CinA HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 262 407 1.0E-44 T 29-03-2018 IPR008136 CinA, C-terminal HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 Pfam PF02464 Competence-damaged protein 255 407 3.7E-56 T 29-03-2018 IPR008136 CinA, C-terminal HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 Pfam PF00994 Probable molybdopterin binding domain 5 169 8.7E-39 T 29-03-2018 IPR001453 MoaB/Mog domain HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 164 1.3E-31 T 29-03-2018 IPR001453 MoaB/Mog domain HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 Gene3D G3DSA:3.40.980.10 1 171 7.3E-48 T 29-03-2018 IPR001453 MoaB/Mog domain HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 SUPERFAMILY SSF53218 1 205 2.49E-45 T 29-03-2018 IPR001453 MoaB/Mog domain HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 408 1.5E-126 T 29-03-2018 IPR008135 Competence-induced protein CinA HVS_RS07505 2d0f0f043940356eee0f68f3a3d57510 413 Gene3D G3DSA:3.90.950.20 246 412 1.1E-57 T 29-03-2018 HVS_RS15140 fb41cc1cbcfc174c6fd3ca2fc0170683 211 Pfam PF00297 Ribosomal protein L3 99 182 1.8E-12 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15140 fb41cc1cbcfc174c6fd3ca2fc0170683 211 SUPERFAMILY SSF50447 5 209 1.24E-75 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS15140 fb41cc1cbcfc174c6fd3ca2fc0170683 211 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site HVS_RS15140 fb41cc1cbcfc174c6fd3ca2fc0170683 211 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 204 6.7E-87 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15140 fb41cc1cbcfc174c6fd3ca2fc0170683 211 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 207 39.261 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15140 fb41cc1cbcfc174c6fd3ca2fc0170683 211 Gene3D G3DSA:4.10.960.10 58 165 8.9E-30 T 29-03-2018 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 Pfam PF00085 Thioredoxin 6 108 5.2E-35 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 10 108 2.0E-39 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 SUPERFAMILY SSF52833 5 108 1.4E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 PRINTS PR00421 Thioredoxin family signature 33 42 1.1E-8 T 29-03-2018 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 PRINTS PR00421 Thioredoxin family signature 73 84 1.1E-8 T 29-03-2018 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 PRINTS PR00421 Thioredoxin family signature 25 33 1.1E-8 T 29-03-2018 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 PIRSF PIRSF000077 3 109 9.9E-42 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HVS_RS11265 68ffeb743985db5aeae90bb75c9ce2f0 109 Gene3D G3DSA:3.40.30.10 1 109 4.5E-38 T 29-03-2018 HVS_RS07705 a605966fbbbf9d7e4f7bc51292b9011a 728 SUPERFAMILY SSF63446 661 727 4.22E-14 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07705 a605966fbbbf9d7e4f7bc51292b9011a 728 Pfam PF00404 Dockerin type I repeat 664 684 2.4E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07705 a605966fbbbf9d7e4f7bc51292b9011a 728 Pfam PF13287 Fn3 associated 50 140 1.5E-12 T 29-03-2018 IPR026876 Fn3 associated repeat HVS_RS07705 a605966fbbbf9d7e4f7bc51292b9011a 728 Pfam PF08757 CotH kinase protein 207 550 3.0E-64 T 29-03-2018 IPR014867 Spore coat protein CotH HVS_RS07705 a605966fbbbf9d7e4f7bc51292b9011a 728 Gene3D G3DSA:2.60.40.10 38 138 1.3E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 SUPERFAMILY SSF47781 529 614 2.7E-21 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Pfam PF12826 Helix-hairpin-helix motif 566 614 7.5E-10 T 29-03-2018 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 SMART SM00278 593 612 0.76 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 SMART SM00278 561 580 12.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 612 29.271 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 593 7.8E-189 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Gene3D G3DSA:4.10.860.10 182 241 1.1E-19 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 SUPERFAMILY SSF82771 14 98 1.31E-25 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 SUPERFAMILY SSF46600 190 243 1.31E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Pfam PF01541 GIY-YIG catalytic domain 15 91 1.1E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Pfam PF02151 UvrB/uvrC motif 205 238 1.3E-11 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Gene3D G3DSA:3.40.1440.10 2 99 2.2E-27 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 388 546 1.4E-49 T 29-03-2018 IPR001162 UvrC family homology region HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 SMART SM00465 14 96 3.0E-28 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily HVS_RS12900 05f55a94fedb4645cbd647829d59e5ca 615 Gene3D G3DSA:1.10.150.20 560 615 5.3E-17 T 29-03-2018 HVS_RS06885 e1f21c58ae2238c1d5d33fd1b992a8b2 169 SUPERFAMILY SSF55729 46 142 4.43E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS06885 e1f21c58ae2238c1d5d33fd1b992a8b2 169 Pfam PF00583 Acetyltransferase (GNAT) family 39 140 3.8E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS06885 e1f21c58ae2238c1d5d33fd1b992a8b2 169 Gene3D G3DSA:3.40.630.30 8 154 6.6E-16 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SUPERFAMILY SSF55681 471 689 5.96E-43 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SMART SM00873 219 392 2.9E-92 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Pfam PF01588 Putative tRNA binding domain 45 150 8.7E-22 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SUPERFAMILY SSF46955 410 479 8.15E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SUPERFAMILY SSF54991 697 795 2.22E-32 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Pfam PF03483 B3/4 domain 220 390 1.8E-70 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:2.40.50.140 54 149 5.9E-41 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SMART SM00896 702 795 2.4E-45 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:3.30.930.10 494 689 9.7E-36 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SUPERFAMILY SSF56037 208 401 4.97E-72 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SMART SM00874 409 475 1.4E-30 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Pfam PF03147 Ferredoxin-fold anticodon binding domain 702 795 2.9E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:3.30.56.10 407 479 1.5E-24 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:3.30.56.10 1 53 1.0E-13 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:3.30.56.10 150 192 2.5E-13 T 29-03-2018 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 789 44.164 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Pfam PF03484 tRNA synthetase B5 domain 413 475 9.5E-24 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:3.30.70.380 698 795 3.2E-29 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 Gene3D G3DSA:3.50.40.10 202 403 2.5E-76 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 795 1.4E-268 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HVS_RS11360 c839ea4d24a1e43a70c4bf3c9fd6ae08 795 SUPERFAMILY SSF50249 35 197 1.98E-45 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SUPERFAMILY SSF47090 406 467 3.61E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SMART SM00228 90 161 4.4E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Pfam PF13180 PDZ domain 91 170 2.1E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Gene3D G3DSA:3.30.750.44 20 97 2.8E-13 T 29-03-2018 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Gene3D G3DSA:2.30.42.10 98 170 3.0E-19 T 29-03-2018 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SUPERFAMILY SSF50156 62 182 1.6E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SMART SM00245 163 384 3.4E-48 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Gene3D G3DSA:3.90.226.10 171 400 2.7E-49 T 29-03-2018 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SUPERFAMILY SSF52096 349 388 1.04E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SUPERFAMILY SSF52096 28 108 1.04E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 SUPERFAMILY SSF52096 181 317 1.04E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Gene3D G3DSA:1.10.101.10 401 475 9.2E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Pfam PF03572 Peptidase family S41 187 381 2.2E-40 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 51 386 4.4E-77 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HVS_RS01765 6f075c1e627f4714313cf70e98a82531 491 Pfam PF01471 Putative peptidoglycan binding domain 412 465 2.4E-5 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 SUPERFAMILY SSF46589 814 878 6.8E-17 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Gene3D G3DSA:3.40.50.620 25 206 2.9E-46 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Gene3D G3DSA:3.40.50.620 270 517 1.3E-76 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 SUPERFAMILY SSF50677 193 343 4.84E-68 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 TIGRFAM TIGR00422 valS: valine--tRNA ligase 5 861 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Gene3D G3DSA:1.10.287.380 807 877 7.4E-26 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 SUPERFAMILY SSF47323 576 829 6.17E-71 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Pfam PF08264 Anticodon-binding domain of tRNA 607 752 1.1E-47 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Gene3D G3DSA:1.10.730.10 518 746 2.2E-80 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 SUPERFAMILY SSF52374 2 192 5.35E-145 T 29-03-2018 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 SUPERFAMILY SSF52374 342 573 5.35E-145 T 29-03-2018 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Hamap MF_02004 Valine--tRNA ligase [valS]. 4 879 16.116 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 PRINTS PR00986 Valyl-tRNA synthetase signature 347 360 4.3E-40 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 4.3E-40 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 PRINTS PR00986 Valyl-tRNA synthetase signature 232 249 4.3E-40 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 4.3E-40 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 PRINTS PR00986 Valyl-tRNA synthetase signature 476 494 4.3E-40 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Gene3D G3DSA:3.90.740.10 207 236 1.9E-8 T 29-03-2018 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 564 1.6E-216 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS02595 9f0a4a72f4f1e067b03c4740cc2b4295 880 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 1.1E-21 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 HVS_RS04260 d2773f92e42e83a39e5d7783fe20bd56 482 Pfam PF14319 Transposase zinc-binding domain 32 140 1.1E-27 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS04260 d2773f92e42e83a39e5d7783fe20bd56 482 Pfam PF04986 Putative transposase 167 336 2.7E-23 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS14105 a02e81f2dde877c0c975b5034d372043 322 SMART SM00327 81 281 1.5E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14105 a02e81f2dde877c0c975b5034d372043 322 Pfam PF07584 Aerotolerance regulator N-terminal 7 68 3.1E-8 T 29-03-2018 IPR024163 Aerotolerance regulator, N-terminal HVS_RS14105 a02e81f2dde877c0c975b5034d372043 322 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 10 73 7.2E-8 T 29-03-2018 IPR011933 Double transmembrane domain HVS_RS14105 a02e81f2dde877c0c975b5034d372043 322 Pfam PF00092 von Willebrand factor type A domain 83 274 1.1E-31 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14105 a02e81f2dde877c0c975b5034d372043 322 Gene3D G3DSA:3.40.50.410 77 302 5.0E-48 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14105 a02e81f2dde877c0c975b5034d372043 322 SUPERFAMILY SSF53300 58 276 1.11E-38 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS04760 a42a85903930ec4d0760430b05eb4cd1 452 Gene3D G3DSA:3.30.420.10 150 328 1.6E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS04760 a42a85903930ec4d0760430b05eb4cd1 452 Pfam PF09299 Mu transposase, C-terminal 337 396 1.0E-11 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal HVS_RS04760 a42a85903930ec4d0760430b05eb4cd1 452 SUPERFAMILY SSF53098 152 315 2.78E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS04760 a42a85903930ec4d0760430b05eb4cd1 452 Pfam PF00665 Integrase core domain 158 272 9.2E-18 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS04760 a42a85903930ec4d0760430b05eb4cd1 452 SUPERFAMILY SSF46689 50 133 6.09E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS13115 a42a85903930ec4d0760430b05eb4cd1 452 Gene3D G3DSA:3.30.420.10 150 328 1.6E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13115 a42a85903930ec4d0760430b05eb4cd1 452 Pfam PF09299 Mu transposase, C-terminal 337 396 1.0E-11 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal HVS_RS13115 a42a85903930ec4d0760430b05eb4cd1 452 SUPERFAMILY SSF53098 152 315 2.78E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13115 a42a85903930ec4d0760430b05eb4cd1 452 Pfam PF00665 Integrase core domain 158 272 9.2E-18 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS13115 a42a85903930ec4d0760430b05eb4cd1 452 SUPERFAMILY SSF46689 50 133 6.09E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS04235 a42a85903930ec4d0760430b05eb4cd1 452 Gene3D G3DSA:3.30.420.10 150 328 1.6E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS04235 a42a85903930ec4d0760430b05eb4cd1 452 Pfam PF09299 Mu transposase, C-terminal 337 396 1.0E-11 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal HVS_RS04235 a42a85903930ec4d0760430b05eb4cd1 452 SUPERFAMILY SSF53098 152 315 2.78E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS04235 a42a85903930ec4d0760430b05eb4cd1 452 Pfam PF00665 Integrase core domain 158 272 9.2E-18 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS04235 a42a85903930ec4d0760430b05eb4cd1 452 SUPERFAMILY SSF46689 50 133 6.09E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 SUPERFAMILY SSF55979 123 242 3.73E-24 T 29-03-2018 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 SUPERFAMILY SSF55979 244 364 3.59E-33 T 29-03-2018 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 Gene3D G3DSA:3.10.150.10 1 121 2.2E-21 T 29-03-2018 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 128 239 5.8E-30 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 SMART SM00480 17 360 1.2E-110 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 Gene3D G3DSA:3.10.150.10 247 365 5.0E-29 T 29-03-2018 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 PIRSF PIRSF000804 1 365 1.0E-112 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 363 1.2E-96 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 243 363 1.8E-26 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 SUPERFAMILY SSF55979 1 118 5.61E-23 T 29-03-2018 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 Gene3D G3DSA:3.10.150.10 122 245 6.2E-30 T 29-03-2018 HVS_RS00010 dbeb2ef50f70ccf3b682d3418eb276ba 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 1.6E-22 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS05790 76a73c43e8fd9041c332044b2de169b1 343 Gene3D G3DSA:3.30.420.10 177 339 7.9E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05790 76a73c43e8fd9041c332044b2de169b1 343 Gene3D G3DSA:2.20.25.10 7 49 7.5E-5 T 29-03-2018 HVS_RS05790 76a73c43e8fd9041c332044b2de169b1 343 SUPERFAMILY SSF53098 179 327 1.54E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05790 76a73c43e8fd9041c332044b2de169b1 343 Pfam PF13610 DDE domain 179 315 5.6E-32 T 29-03-2018 IPR032874 DDE domain HVS_RS05790 76a73c43e8fd9041c332044b2de169b1 343 SUPERFAMILY SSF57783 5 43 5.38E-5 T 29-03-2018 HVS_RS05790 76a73c43e8fd9041c332044b2de169b1 343 Pfam PF03811 InsA N-terminal domain 5 36 3.6E-8 T 29-03-2018 IPR003220 InsA N-terminal domain GO:0006313 HVS_RS05685 76a73c43e8fd9041c332044b2de169b1 343 Gene3D G3DSA:3.30.420.10 177 339 7.9E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05685 76a73c43e8fd9041c332044b2de169b1 343 Gene3D G3DSA:2.20.25.10 7 49 7.5E-5 T 29-03-2018 HVS_RS05685 76a73c43e8fd9041c332044b2de169b1 343 SUPERFAMILY SSF53098 179 327 1.54E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05685 76a73c43e8fd9041c332044b2de169b1 343 Pfam PF13610 DDE domain 179 315 5.6E-32 T 29-03-2018 IPR032874 DDE domain HVS_RS05685 76a73c43e8fd9041c332044b2de169b1 343 SUPERFAMILY SSF57783 5 43 5.38E-5 T 29-03-2018 HVS_RS05685 76a73c43e8fd9041c332044b2de169b1 343 Pfam PF03811 InsA N-terminal domain 5 36 3.6E-8 T 29-03-2018 IPR003220 InsA N-terminal domain GO:0006313 HVS_RS15290 454291952b91a5b6a73cd3c6cc3e6032 177 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 6.9E-28 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HVS_RS15290 454291952b91a5b6a73cd3c6cc3e6032 177 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 2.8E-29 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HVS_RS15290 454291952b91a5b6a73cd3c6cc3e6032 177 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 116 172 3.7E-31 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal HVS_RS15290 454291952b91a5b6a73cd3c6cc3e6032 177 SUPERFAMILY SSF69754 3 102 2.35E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HVS_RS15290 454291952b91a5b6a73cd3c6cc3e6032 177 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 176 24.368 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid HVS_RS15290 454291952b91a5b6a73cd3c6cc3e6032 177 Gene3D G3DSA:3.30.160.100 1 96 7.7E-31 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 Pfam PF07478 D-ala D-ala ligase C-terminus 154 357 7.4E-82 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 Gene3D G3DSA:3.30.470.20 222 369 5.9E-47 T 29-03-2018 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 359 4.5E-115 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 360 44.121 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 Gene3D G3DSA:3.40.50.20 1 147 2.7E-44 T 29-03-2018 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 113 124 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 301 330 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 Gene3D G3DSA:3.30.1490.20 148 221 3.9E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 PIRSF PIRSF039102 2 367 3.8E-124 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 SUPERFAMILY SSF52440 4 145 2.11E-37 T 29-03-2018 IPR016185 Pre-ATP-grasp domain HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 SUPERFAMILY SSF56059 146 366 8.31E-64 T 29-03-2018 HVS_RS01730 6fa745a579ed51f23f1dd52ff84553ae 372 Pfam PF01820 D-ala D-ala ligase N-terminus 6 136 7.4E-32 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS10370 47bf1132f9042c44933bfef325b70451 120 PIRSF PIRSF028777 1 120 1.9E-43 T 29-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 HVS_RS10370 47bf1132f9042c44933bfef325b70451 120 Pfam PF03733 Inner membrane component domain 4 54 9.3E-21 T 29-03-2018 IPR005185 Inner membrane component domain HVS_RS10370 47bf1132f9042c44933bfef325b70451 120 Pfam PF03733 Inner membrane component domain 67 116 8.4E-20 T 29-03-2018 IPR005185 Inner membrane component domain HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 SUPERFAMILY SSF49313 425 496 3.92E-6 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 Gene3D G3DSA:2.60.120.200 226 410 1.7E-37 T 29-03-2018 HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 Gene3D G3DSA:2.60.40.10 411 495 5.2E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 Pfam PF00395 S-layer homology domain 24 67 2.3E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 Pfam PF00395 S-layer homology domain 86 129 2.3E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 SUPERFAMILY SSF49899 229 417 1.9E-31 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS06035 f480b4f520e856fb08d856f152f0a0b6 521 Pfam PF05735 Thrombospondin C-terminal region 241 415 8.0E-29 T 29-03-2018 IPR008859 Thrombospondin, C-terminal GO:0005509|GO:0005576|GO:0007155 Reactome: R-HSA-186797 HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 SUPERFAMILY SSF49313 425 496 3.92E-6 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 Gene3D G3DSA:2.60.120.200 226 410 1.7E-37 T 29-03-2018 HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 Gene3D G3DSA:2.60.40.10 411 495 5.2E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 Pfam PF00395 S-layer homology domain 24 67 2.3E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 Pfam PF00395 S-layer homology domain 86 129 2.3E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 SUPERFAMILY SSF49899 229 417 1.9E-31 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS14790 f480b4f520e856fb08d856f152f0a0b6 521 Pfam PF05735 Thrombospondin C-terminal region 241 415 8.0E-29 T 29-03-2018 IPR008859 Thrombospondin, C-terminal GO:0005509|GO:0005576|GO:0007155 Reactome: R-HSA-186797 HVS_RS06530 16f9c71ff6d39c670deb31610b243ddf 409 Pfam PF00872 Transposase, Mutator family 21 377 1.1E-136 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HVS_RS09405 c2112fcc38ea6da415432de9be78ab55 296 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 93 282 1.6E-8 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HVS_RS09405 c2112fcc38ea6da415432de9be78ab55 296 Gene3D G3DSA:3.40.190.10 181 284 5.9E-7 T 29-03-2018 HVS_RS09405 c2112fcc38ea6da415432de9be78ab55 296 Gene3D G3DSA:3.40.190.10 64 180 0.066 T 29-03-2018 HVS_RS09405 c2112fcc38ea6da415432de9be78ab55 296 SUPERFAMILY SSF53850 92 284 1.3E-15 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 SUPERFAMILY SSF53300 377 558 1.93E-32 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2420 2499 3.9E-19 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 SMART SM00306 2630 2724 1.0E-12 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF07591 Pretoxin HINT domain 2638 2767 1.0E-30 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Gene3D G3DSA:2.170.16.10 2623 2766 4.6E-37 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 1588 1625 6.9E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 1784 1821 3.4E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 1868 1903 2.6E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 2139 2176 1.5E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 2160 2189 1.1E-4 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 2098 2134 2.3E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 1952 1988 4.0E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 2036 2072 2.4E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 1994 2029 4.4E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF05593 RHS Repeat 1714 1748 5.1E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 PRINTS PR01217 Proline rich extensin signature 895 907 8.5E-9 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 PRINTS PR01217 Proline rich extensin signature 908 929 8.5E-9 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 PRINTS PR01217 Proline rich extensin signature 1067 1092 8.5E-9 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 PRINTS PR01217 Proline rich extensin signature 856 868 8.5E-9 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 PRINTS PR01217 Proline rich extensin signature 872 888 8.5E-9 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 SUPERFAMILY SSF49384 931 1066 7.85E-21 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 SUPERFAMILY SSF51294 2632 2765 6.67E-27 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2057 2094 5.5E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1994 2034 1.4E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1826 1862 0.0025 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1714 1747 7.5E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1609 1646 5.8E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1805 1841 0.0014 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1952 1990 5.1E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1577 1608 0.0013 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1651 1688 7.5E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1868 1909 1.6E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2084 2114 0.0018 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1672 1712 0.0012 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2098 2132 7.0E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1763 1803 0.0011 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1503 1538 2.4E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2119 2159 3.3E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2036 2077 1.1E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2160 2188 9.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Gene3D G3DSA:2.60.40.680 921 1068 3.7E-22 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2743 2766 0.0039 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Gene3D G3DSA:3.40.1850.10 780 879 6.2E-4 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF00963 Cohesin domain 932 1066 3.3E-23 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Gene3D G3DSA:3.40.50.410 376 572 6.6E-37 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 2632 2702 8.1E-7 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF00092 von Willebrand factor type A domain 382 555 2.9E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Gene3D G3DSA:2.120.10.30 1694 2224 1.5E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF00395 S-layer homology domain 186 228 7.9E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF00395 S-layer homology domain 64 105 3.0E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 Pfam PF00395 S-layer homology domain 123 166 5.6E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 SUPERFAMILY SSF69304 1809 2017 4.51E-7 T 29-03-2018 HVS_RS01840 fc33a5df0b13333a8112fe90429c9706 2893 SMART SM00327 380 563 2.5E-26 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Pfam PF14520 Helix-hairpin-helix domain 88 132 3.3E-4 T 29-03-2018 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Gene3D G3DSA:1.10.150.20 148 202 0.027 T 29-03-2018 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 SUPERFAMILY SSF47781 67 155 1.96E-10 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 5 728 1.3E-207 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Pfam PF13604 AAA domain 319 499 5.7E-47 T 29-03-2018 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 SUPERFAMILY SSF52540 319 709 2.68E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 1 730 27.898 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Pfam PF14490 Helix-hairpin-helix containing domain 138 228 8.6E-33 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Gene3D G3DSA:1.10.150.20 77 147 3.3E-9 T 29-03-2018 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Pfam PF13538 UvrD-like helicase C-terminal domain 657 704 1.0E-17 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 SMART SM00382 332 451 1.1E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Gene3D G3DSA:3.40.50.300 493 717 1.1E-33 T 29-03-2018 HVS_RS01355 41f30a226659116781ed1367d8f8788d 735 Gene3D G3DSA:3.40.50.300 277 492 8.1E-37 T 29-03-2018 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 PRINTS PR00151 Porphobilinogen deaminase signature 221 238 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 PRINTS PR00151 Porphobilinogen deaminase signature 136 153 1.2E-31 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 SUPERFAMILY SSF54782 214 287 2.62E-16 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 Gene3D G3DSA:3.30.160.40 212 289 4.4E-14 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 222 238 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 286 2.0E-14 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 Gene3D G3DSA:3.40.190.10 1 104 3.9E-38 T 29-03-2018 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 285 4.5E-85 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 SUPERFAMILY SSF53850 2 203 1.74E-62 T 29-03-2018 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 202 5.1E-67 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 Gene3D G3DSA:3.40.190.10 105 192 1.7E-26 T 29-03-2018 HVS_RS02610 c788a42c0d4e0c79e44cfb31b9b0bfcf 289 PIRSF PIRSF001438 1 289 9.9E-94 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 Hamap MF_00740 Phosphopentomutase [deoB]. 1 384 50.57 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 Gene3D G3DSA:3.30.70.1250 97 213 7.1E-52 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 SUPERFAMILY SSF143856 98 213 6.8E-48 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 Gene3D G3DSA:3.40.720.10 279 386 2.4E-10 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 SUPERFAMILY SSF53649 214 387 1.81E-72 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 SUPERFAMILY SSF53649 1 98 1.81E-72 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 374 3.2E-152 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 PIRSF PIRSF001491 1 388 1.3E-151 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 HVS_RS09515 a129fcca834c75d26fb9058ce609e9e3 389 Pfam PF01676 Metalloenzyme superfamily 2 374 1.3E-40 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 TIGRFAM TIGR01529 argR_whole: arginine repressor 4 147 8.8E-46 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 SUPERFAMILY SSF46785 2 68 8.59E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 SUPERFAMILY SSF55252 79 146 2.75E-21 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 PRINTS PR01467 Bacterial arginine repressor signature 87 100 5.2E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 PRINTS PR01467 Bacterial arginine repressor signature 20 33 5.2E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 PRINTS PR01467 Bacterial arginine repressor signature 117 132 5.2E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 PRINTS PR01467 Bacterial arginine repressor signature 36 51 5.2E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 Gene3D G3DSA:1.10.10.10 3 63 1.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 Pfam PF02863 Arginine repressor, C-terminal domain 79 145 5.5E-30 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 138 2.0E-17 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 Gene3D G3DSA:3.30.1360.40 73 145 1.0E-28 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 Pfam PF01316 Arginine repressor, DNA binding domain 2 65 1.3E-23 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 HVS_RS09745 9285b6454aeae8d866a5ce8a39dd076c 155 Hamap MF_00173 Arginine repressor [argR]. 1 151 63.278 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 SUPERFAMILY SSF53335 75 531 3.16E-118 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 SUPERFAMILY SSF53335 6 44 3.16E-118 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 Pfam PF12161 HsdM N-terminal domain 9 140 7.6E-23 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 Gene3D G3DSA:3.40.50.150 171 575 6.1E-50 T 29-03-2018 HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 173 189 4.6E-7 T 29-03-2018 HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 278 290 4.6E-7 T 29-03-2018 HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 206 220 4.6E-7 T 29-03-2018 HVS_RS06585 b201c305dcbe644c893faf211578bcab 672 Pfam PF02384 N-6 DNA Methylase 154 465 1.6E-56 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HVS_RS04445 d3c3941abebf35c2d68b2e4bf7f289bc 389 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 9 383 1.8E-160 T 29-03-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase HVS_RS04445 d3c3941abebf35c2d68b2e4bf7f289bc 389 Gene3D G3DSA:3.40.640.10 6 251 3.7E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS04445 d3c3941abebf35c2d68b2e4bf7f289bc 389 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 380 1.8E-134 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HVS_RS04445 d3c3941abebf35c2d68b2e4bf7f289bc 389 SUPERFAMILY SSF53383 9 385 3.71E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS04445 d3c3941abebf35c2d68b2e4bf7f289bc 389 PIRSF PIRSF000390 6 388 4.5E-129 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HVS_RS04445 d3c3941abebf35c2d68b2e4bf7f289bc 389 Gene3D G3DSA:3.90.1150.10 252 389 1.7E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 SUPERFAMILY SSF51735 1 332 2.07E-99 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 2.5E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 2.5E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 2.5E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 2.5E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 Gene3D G3DSA:3.40.50.720 1 206 1.4E-39 T 29-03-2018 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 Gene3D G3DSA:3.90.25.10 248 335 1.6E-25 T 29-03-2018 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 Gene3D G3DSA:3.90.25.10 207 247 1.6E-9 T 29-03-2018 HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 2.1E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS13380 88963eb7b07e608df6ebaa0fcfc82377 335 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 334 1.8E-143 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 HVS_RS00455 c88bb51c693ce70275feef6279967d46 800 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 37 796 1.1E-205 T 29-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS00455 c88bb51c693ce70275feef6279967d46 800 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 610 794 6.3E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS00455 c88bb51c693ce70275feef6279967d46 800 Gene3D G3DSA:3.30.1640.10 311 403 0.0024 T 29-03-2018 HVS_RS00455 c88bb51c693ce70275feef6279967d46 800 Gene3D G3DSA:3.60.40.10 575 800 5.5E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS00455 c88bb51c693ce70275feef6279967d46 800 SMART SM00331 583 795 1.0E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS00455 c88bb51c693ce70275feef6279967d46 800 SUPERFAMILY SSF81606 584 795 5.49E-17 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 Gene3D G3DSA:1.10.3810.10 74 272 4.0E-74 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 Gene3D G3DSA:3.40.710.10 274 689 5.5E-100 T 29-03-2018 HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 Pfam PF00905 Penicillin binding protein transpeptidase domain 360 636 1.3E-26 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 SUPERFAMILY SSF53955 71 276 1.12E-69 T 29-03-2018 IPR023346 Lysozyme-like domain HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 92 641 6.6E-170 T 29-03-2018 HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 SUPERFAMILY SSF56601 289 705 8.16E-110 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 SUPERFAMILY SSF56601 239 257 8.16E-110 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS03230 0ebf48bcd130d6548b064abec3caeee6 858 Pfam PF00912 Transglycosylase 87 253 1.7E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 345 433 8.6E-5 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 SUPERFAMILY SSF102114 129 417 5.36E-55 T 29-03-2018 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 SMART SM00876 341 434 1.0E-10 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 SMART SM00729 168 376 1.7E-24 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 121 432 3.7E-88 T 29-03-2018 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 Pfam PF11823 Protein of unknown function (DUF3343) 28 95 4.7E-14 T 29-03-2018 IPR021778 Domain of unknown function DUF3343 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 Pfam PF04055 Radical SAM superfamily 172 327 3.5E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS07845 688778fc2300d20a8df0992b83b37e1c 449 Gene3D G3DSA:3.20.20.70 109 442 6.1E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 SMART SM00448 9 119 9.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 SUPERFAMILY SSF52738 165 350 5.62E-66 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 Gene3D G3DSA:3.40.50.180 170 351 1.0E-70 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 SUPERFAMILY SSF52172 7 109 1.57E-28 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 Pfam PF00072 Response regulator receiver domain 11 110 1.6E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 Pfam PF01339 CheB methylesterase 167 345 1.2E-57 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 PIRSF PIRSF000876 6 351 8.2E-121 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 9 350 36.074 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS09675 279a108537bdb8efec9253ce74af26c0 351 Gene3D G3DSA:3.40.50.2300 4 169 1.5E-29 T 29-03-2018 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 680 758 14.0 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 491 569 3.6E-4 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 398 478 0.15 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 25 116 4.3 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 584 661 1.5E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 771 853 0.024 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SMART SM00060 865 943 1.6E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SUPERFAMILY SSF49265 773 954 4.29E-21 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SUPERFAMILY SSF49265 489 657 5.45E-19 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SUPERFAMILY SSF49265 35 201 6.35E-9 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 22 139 8.6E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 140 213 0.48 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 867 959 1.5E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 398 487 4.3E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 676 770 1.0E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 771 866 2.9E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SUPERFAMILY SSF49265 398 477 5.18E-9 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 SUPERFAMILY SSF49265 683 766 3.73E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 488 672 3.3E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Pfam PF00041 Fibronectin type III domain 773 846 2.2E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Pfam PF00395 S-layer homology domain 1085 1127 0.0067 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Pfam PF00395 S-layer homology domain 1017 1060 1.6E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Pfam PF00395 S-layer homology domain 958 1001 8.0E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01595 4aa4efd30c10594a6dce50edaf8b106a 1139 Gene3D G3DSA:2.60.40.10 306 397 0.024 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 ProSitePatterns PS00761 Signal peptidases I signature 3. 157 170 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 SUPERFAMILY SSF51306 102 189 1.26E-41 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 SUPERFAMILY SSF51306 27 75 1.26E-41 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 188 1.2E-39 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 Pfam PF10502 Signal peptidase, peptidase S26 104 184 3.8E-6 T 29-03-2018 IPR019533 Peptidase S26 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 Gene3D G3DSA:2.10.109.10 24 189 3.0E-37 T 29-03-2018 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 Pfam PF00717 Peptidase S24-like 34 71 8.8E-6 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 3.6E-18 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 107 119 3.6E-18 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS14510 137759ddc038a6f606efa873491d39ff 189 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 152 171 3.6E-18 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS08110 4289f8a2b3dacd033d2778d2c8c8fc58 295 SUPERFAMILY SSF53697 102 271 1.88E-33 T 29-03-2018 HVS_RS08110 4289f8a2b3dacd033d2778d2c8c8fc58 295 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 77 1.0E-13 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 HVS_RS08110 4289f8a2b3dacd033d2778d2c8c8fc58 295 Gene3D G3DSA:3.40.50.10490 97 284 2.4E-28 T 29-03-2018 HVS_RS08110 4289f8a2b3dacd033d2778d2c8c8fc58 295 Pfam PF01380 SIS domain 132 258 2.3E-26 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HVS_RS08110 4289f8a2b3dacd033d2778d2c8c8fc58 295 SUPERFAMILY SSF46689 7 82 9.32E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS08110 4289f8a2b3dacd033d2778d2c8c8fc58 295 Gene3D G3DSA:1.10.10.10 2 82 5.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 Gene3D G3DSA:3.20.20.100 1 258 4.2E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 213 228 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 SUPERFAMILY SSF51430 1 254 3.27E-90 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PIRSF PIRSF000097 1 104 3.6E-34 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PIRSF PIRSF000097 102 255 7.2E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 28 45 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PRINTS PR00069 Aldo-keto reductase signature 109 126 1.4E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PRINTS PR00069 Aldo-keto reductase signature 80 98 1.4E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PRINTS PR00069 Aldo-keto reductase signature 24 48 1.4E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PRINTS PR00069 Aldo-keto reductase signature 180 204 1.4E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 PRINTS PR00069 Aldo-keto reductase signature 143 172 1.4E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 109 126 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HVS_RS10820 97d05f532c6fe61b98bbaae82ce1a5ec 259 Pfam PF00248 Aldo/keto reductase family 4 245 1.9E-54 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS02665 d64f80110a04ec5b6c437ee2bb1780a7 121 Gene3D G3DSA:3.30.110.40 41 119 1.0E-18 T 29-03-2018 IPR001455 TusA-like domain HVS_RS02665 d64f80110a04ec5b6c437ee2bb1780a7 121 Pfam PF01206 Sulfurtransferase TusA 50 118 1.1E-18 T 29-03-2018 IPR001455 TusA-like domain HVS_RS02665 d64f80110a04ec5b6c437ee2bb1780a7 121 SUPERFAMILY SSF64307 44 119 5.1E-20 T 29-03-2018 IPR001455 TusA-like domain HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 SMART SM00388 50 120 3.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 168 276 2.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 221 231 8.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 238 256 8.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 262 275 8.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 PRINTS PR00344 Bacterial sensor protein C-terminal signature 203 217 8.3E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 Gene3D G3DSA:3.30.565.10 134 305 5.9E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 SUPERFAMILY SSF55874 109 277 1.7E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 SUPERFAMILY SSF47384 42 120 1.0E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 Pfam PF00512 His Kinase A (phospho-acceptor) domain 51 120 8.4E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 Gene3D G3DSA:1.10.287.130 40 116 1.4E-16 T 29-03-2018 HVS_RS15780 8dee400c6bc4aae283c936b1ea2c24a2 310 SMART SM00387 166 278 3.9E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS08310 d47e3be406a0a01c622bee08c15365cc 152 SUPERFAMILY SSF55729 1 136 3.44E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS08310 d47e3be406a0a01c622bee08c15365cc 152 Pfam PF13673 Acetyltransferase (GNAT) domain 50 148 1.8E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS08310 d47e3be406a0a01c622bee08c15365cc 152 Gene3D G3DSA:3.40.630.30 1 147 3.6E-22 T 29-03-2018 HVS_RS01580 66447ab617b4184e8630363ee39c30b3 102 Gene3D G3DSA:3.30.2310.20 1 100 2.1E-11 T 29-03-2018 HVS_RS01580 66447ab617b4184e8630363ee39c30b3 102 SUPERFAMILY SSF143011 1 91 5.23E-6 T 29-03-2018 IPR035095 Toxin RelE-like domain HVS_RS01580 66447ab617b4184e8630363ee39c30b3 102 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 98 8.5E-15 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family HVS_RS02445 4ead5a8e9f32ba322ded50de872ac248 200 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 88 188 5.0E-28 T 29-03-2018 HVS_RS02445 4ead5a8e9f32ba322ded50de872ac248 200 SMART SM00471 34 157 1.7E-6 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS02445 4ead5a8e9f32ba322ded50de872ac248 200 SUPERFAMILY SSF109604 12 199 2.48E-43 T 29-03-2018 HVS_RS02445 4ead5a8e9f32ba322ded50de872ac248 200 Pfam PF13023 HD domain 19 175 3.8E-21 T 29-03-2018 IPR006674 HD domain HVS_RS02445 4ead5a8e9f32ba322ded50de872ac248 200 Gene3D G3DSA:1.10.3210.10 1 195 1.6E-51 T 29-03-2018 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 SUPERFAMILY SSF46689 150 200 5.73E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 SUPERFAMILY SSF52172 1 139 2.99E-33 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 Pfam PF00072 Response regulator receiver domain 4 120 2.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 SMART SM00342 166 248 3.0E-12 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 Gene3D G3DSA:1.10.10.60 147 203 3.4E-16 T 29-03-2018 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 Gene3D G3DSA:1.10.10.60 215 251 9.5E-4 T 29-03-2018 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 SMART SM00448 2 120 9.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 Gene3D G3DSA:3.40.50.2300 1 146 2.9E-31 T 29-03-2018 HVS_RS00270 c3911f9f851896503c099e8c9710aad4 254 Pfam PF12833 Helix-turn-helix domain 172 249 6.2E-10 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS14650 e49d04250f671075b07f39f12a2e6059 471 Gene3D G3DSA:3.90.1150.10 255 391 9.6E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS14650 e49d04250f671075b07f39f12a2e6059 471 Gene3D G3DSA:3.90.100.10 392 471 1.7E-19 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HVS_RS14650 e49d04250f671075b07f39f12a2e6059 471 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 4 296 2.6E-69 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 HVS_RS14650 e49d04250f671075b07f39f12a2e6059 471 Gene3D G3DSA:3.40.640.10 51 254 2.1E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS14650 e49d04250f671075b07f39f12a2e6059 471 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 400 451 5.2E-10 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HVS_RS14650 e49d04250f671075b07f39f12a2e6059 471 SUPERFAMILY SSF53383 4 374 2.1E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 SUPERFAMILY SSF52540 4 337 1.29E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 Gene3D G3DSA:3.30.450.90 1 100 2.3E-23 T 29-03-2018 HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 Pfam PF00437 Type II/IV secretion system protein 12 270 1.8E-40 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 Gene3D G3DSA:3.40.50.300 273 347 1.8E-11 T 29-03-2018 HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 Gene3D G3DSA:3.40.50.300 115 272 7.1E-25 T 29-03-2018 HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 SMART SM00382 122 247 6.5E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 3.4E-143 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 HVS_RS10000 48a680ff0359c9708b40810447ed5754 351 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS02110 f9515fdd580f9163162a809956c10343 117 Hamap MF_00674 UPF0251 protein . 2 98 20.817 T 29-03-2018 IPR002852 Uncharacterised protein family UPF0251 HVS_RS02110 f9515fdd580f9163162a809956c10343 117 SUPERFAMILY SSF88659 36 84 2.99E-7 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS02110 f9515fdd580f9163162a809956c10343 117 Pfam PF02001 Protein of unknown function DUF134 3 95 8.4E-22 T 29-03-2018 IPR002852 Uncharacterised protein family UPF0251 HVS_RS02110 f9515fdd580f9163162a809956c10343 117 Gene3D G3DSA:1.10.10.10 28 87 5.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 7 424 28.271 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 Gene3D G3DSA:3.65.10.10 218 424 4.7E-45 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 SUPERFAMILY SSF55205 3 424 4.09E-114 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 Gene3D G3DSA:3.65.10.10 19 217 7.0E-39 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 PIRSF PIRSF000505 1 424 3.4E-96 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 4 421 3.7E-104 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS12675 dfe71ab603f4f81a52ed2253e853f69f 424 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 11 424 3.3E-106 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS15935 9e75df3388017c627958ce499a4ba0a8 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 4.5E-59 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS15935 9e75df3388017c627958ce499a4ba0a8 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 3.9E-48 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS15935 9e75df3388017c627958ce499a4ba0a8 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.97 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS15935 9e75df3388017c627958ce499a4ba0a8 159 SUPERFAMILY SSF75217 1 157 5.56E-58 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS15935 9e75df3388017c627958ce499a4ba0a8 159 PIRSF PIRSF004505 1 159 1.0E-55 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS15935 9e75df3388017c627958ce499a4ba0a8 159 Gene3D G3DSA:3.40.1280.10 1 159 1.1E-60 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 216 1.3E-46 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 Gene3D G3DSA:3.40.1010.10 4 128 2.1E-33 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 PIRSF PIRSF036426 1 255 6.3E-106 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 240 2.2E-97 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 Pfam PF02602 Uroporphyrinogen-III synthase HemD 267 491 4.1E-56 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 Gene3D G3DSA:3.40.50.10090 408 502 5.0E-17 T 29-03-2018 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 SUPERFAMILY SSF69618 253 499 1.03E-58 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 Gene3D G3DSA:3.40.50.10090 285 407 1.0E-26 T 29-03-2018 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 SUPERFAMILY SSF53790 3 255 4.45E-79 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS02615 013c6d2024115149911a1c90dba0ffd1 517 Gene3D G3DSA:3.30.950.10 129 267 1.4E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS08220 061553143490899fc671433df6116a9a 154 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 130 6.3E-32 T 29-03-2018 IPR014229 Sporulation protein YtfJ HVS_RS08220 061553143490899fc671433df6116a9a 154 PIRSF PIRSF021377 1 153 1.4E-51 T 29-03-2018 IPR014229 Sporulation protein YtfJ HVS_RS08220 061553143490899fc671433df6116a9a 154 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 139 1.5E-54 T 29-03-2018 IPR014229 Sporulation protein YtfJ HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 Gene3D G3DSA:3.40.50.980 5 200 2.5E-40 T 29-03-2018 HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 Gene3D G3DSA:3.30.300.30 440 546 1.4E-30 T 29-03-2018 HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 SUPERFAMILY SSF56801 6 541 3.4E-163 T 29-03-2018 HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 Pfam PF00501 AMP-binding enzyme 17 445 5.5E-117 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 Gene3D G3DSA:3.40.50.980 201 353 2.0E-51 T 29-03-2018 HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 Gene3D G3DSA:2.30.38.10 354 438 1.6E-30 T 29-03-2018 HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 29-03-2018 IPR020845 AMP-binding, conserved site HVS_RS04880 734626feb34b67f2d0915002dca2bb2a 554 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 4.8E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 Gene3D G3DSA:3.30.300.30 471 592 6.6E-11 T 29-03-2018 HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 SUPERFAMILY SSF56801 342 582 4.06E-101 T 29-03-2018 HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 SUPERFAMILY SSF56801 23 307 4.06E-101 T 29-03-2018 HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 Gene3D G3DSA:2.30.38.10 394 470 6.5E-20 T 29-03-2018 HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 Gene3D G3DSA:3.40.50.980 26 210 1.3E-21 T 29-03-2018 HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 Pfam PF00501 AMP-binding enzyme 57 476 2.2E-78 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS06165 e1a05bc17fa796dedf2aa009ffe9f7d7 606 Gene3D G3DSA:3.40.50.980 211 393 4.8E-37 T 29-03-2018 HVS_RS11425 72f55fea0a0218036d40f068b53b2488 647 Gene3D G3DSA:3.40.50.300 39 245 9.3E-5 T 29-03-2018 HVS_RS11425 72f55fea0a0218036d40f068b53b2488 647 SUPERFAMILY SSF52540 143 510 4.96E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11425 72f55fea0a0218036d40f068b53b2488 647 Gene3D G3DSA:3.40.50.300 246 606 6.5E-6 T 29-03-2018 HVS_RS13555 08e1abac0f8b61968fa4a02586bd19a0 90 Gene3D G3DSA:2.10.260.10 6 87 7.9E-13 T 29-03-2018 HVS_RS13555 08e1abac0f8b61968fa4a02586bd19a0 90 SUPERFAMILY SSF89447 9 48 5.76E-10 T 29-03-2018 HVS_RS13555 08e1abac0f8b61968fa4a02586bd19a0 90 SMART SM00966 9 52 4.3E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS13555 08e1abac0f8b61968fa4a02586bd19a0 90 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 46 4.6E-12 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS13555 08e1abac0f8b61968fa4a02586bd19a0 90 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 46 1.0E-6 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS13150 08e1abac0f8b61968fa4a02586bd19a0 90 Gene3D G3DSA:2.10.260.10 6 87 7.9E-13 T 29-03-2018 HVS_RS13150 08e1abac0f8b61968fa4a02586bd19a0 90 SUPERFAMILY SSF89447 9 48 5.76E-10 T 29-03-2018 HVS_RS13150 08e1abac0f8b61968fa4a02586bd19a0 90 SMART SM00966 9 52 4.3E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS13150 08e1abac0f8b61968fa4a02586bd19a0 90 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 46 4.6E-12 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS13150 08e1abac0f8b61968fa4a02586bd19a0 90 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 46 1.0E-6 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 SUPERFAMILY SSF55920 132 393 6.8E-46 T 29-03-2018 IPR000994 Peptidase M24 HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 SUPERFAMILY SSF53092 16 135 1.7E-26 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 Gene3D G3DSA:3.90.230.10 134 392 1.1E-44 T 29-03-2018 HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 135 9.4E-12 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 Pfam PF00557 Metallopeptidase family M24 143 378 9.0E-37 T 29-03-2018 IPR000994 Peptidase M24 HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 Gene3D G3DSA:3.40.350.10 6 133 4.3E-15 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 PRINTS PR00599 Methionine aminopeptidase-1 signature 347 359 5.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS10800 a55af046ec3068edca6b636fa9ec8e00 396 PRINTS PR00599 Methionine aminopeptidase-1 signature 242 258 5.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 SUPERFAMILY SSF56024 505 686 1.88E-73 T 29-03-2018 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Gene3D G3DSA:3.30.870.10 322 504 1.6E-18 T 29-03-2018 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Gene3D G3DSA:1.20.58.310 14 117 2.9E-36 T 29-03-2018 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Pfam PF13089 Polyphosphate kinase N-terminal domain 12 118 1.7E-38 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Pfam PF02503 Polyphosphate kinase middle domain 127 327 6.1E-69 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 SUPERFAMILY SSF140356 10 114 3.92E-38 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 SUPERFAMILY SSF143724 116 318 9.81E-61 T 29-03-2018 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 12 681 5.5E-285 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Hamap MF_00347 Polyphosphate kinase [ppk]. 10 686 30.123 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Gene3D G3DSA:3.30.1840.10 118 311 1.2E-67 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Gene3D G3DSA:3.30.870.10 505 691 2.2E-41 T 29-03-2018 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 Pfam PF13090 Polyphosphate kinase C-terminal domain 335 681 1.4E-161 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 PIRSF PIRSF015589 1 699 9.4E-286 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 HVS_RS05130 d3fbe5754f6497aa59542df1792f303e 700 SUPERFAMILY SSF56024 320 498 5.89E-60 T 29-03-2018 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 SMART SM00228 423 504 3.7E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 Gene3D G3DSA:2.30.42.10 421 518 8.4E-18 T 29-03-2018 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 Gene3D G3DSA:2.40.10.10 192 312 4.7E-32 T 29-03-2018 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 PRINTS PR00834 HtrA/DegQ protease family signature 377 394 4.3E-28 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 PRINTS PR00834 HtrA/DegQ protease family signature 355 372 4.3E-28 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 PRINTS PR00834 HtrA/DegQ protease family signature 462 474 4.3E-28 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 PRINTS PR00834 HtrA/DegQ protease family signature 317 341 4.3E-28 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 PRINTS PR00834 HtrA/DegQ protease family signature 243 255 4.3E-28 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 Gene3D G3DSA:2.40.10.10 313 412 3.3E-36 T 29-03-2018 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 Pfam PF13180 PDZ domain 424 512 5.4E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 SUPERFAMILY SSF50156 444 516 1.3E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 Pfam PF13365 Trypsin-like peptidase domain 234 384 6.5E-36 T 29-03-2018 HVS_RS10910 03f0551bfd45f5d5ac73f81e081e4769 518 SUPERFAMILY SSF50494 197 418 4.18E-55 T 29-03-2018 IPR009003 Peptidase S1, PA clan HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 SUPERFAMILY SSF54631 5 122 1.26E-31 T 29-03-2018 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 SUPERFAMILY SSF81891 286 550 1.44E-41 T 29-03-2018 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Gene3D G3DSA:3.30.460.10 133 283 1.4E-39 T 29-03-2018 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 SUPERFAMILY SSF81301 136 284 3.4E-36 T 29-03-2018 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 SMART SM00116 74 121 7.5E-8 T 29-03-2018 IPR000644 CBS domain HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 SMART SM00116 12 59 3.5E-11 T 29-03-2018 IPR000644 CBS domain HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Gene3D G3DSA:3.10.580.10 2 132 2.9E-28 T 29-03-2018 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Pfam PF01743 Poly A polymerase head domain 160 287 2.3E-32 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 312 374 1.4E-10 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Gene3D G3DSA:1.10.3090.10 284 550 1.2E-42 T 29-03-2018 HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Pfam PF00571 CBS domain 67 120 2.4E-11 T 29-03-2018 IPR000644 CBS domain HVS_RS08250 89385916d8ac40d5145c473ba2379b49 553 Pfam PF00571 CBS domain 5 57 4.1E-11 T 29-03-2018 IPR000644 CBS domain HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 SUPERFAMILY SSF63446 478 552 3.14E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 Gene3D G3DSA:1.50.10.10 31 457 3.1E-121 T 29-03-2018 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 425 443 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 523 542 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 Pfam PF00404 Dockerin type I repeat 523 543 3.2E-7 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 Gene3D G3DSA:1.10.1330.10 479 554 3.4E-5 T 29-03-2018 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 Pfam PF00759 Glycosyl hydrolase family 9 32 448 1.9E-121 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 SUPERFAMILY SSF48208 29 457 2.21E-145 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS09245 be33a5d831d99804273f51ffc30e34d4 561 ProSitePatterns PS00018 EF-hand calcium-binding domain. 523 535 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS10435 368a8193b785abc3eee22d895b4a878d 370 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 363 4.2E-137 T 29-03-2018 IPR013438 Sporulation stage V, protein E HVS_RS10435 368a8193b785abc3eee22d895b4a878d 370 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 364 3.3E-124 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 HVS_RS10435 368a8193b785abc3eee22d895b4a878d 370 Pfam PF01098 Cell cycle protein 11 366 1.1E-111 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 HVS_RS13495 108f52548de4e49acb700a2b7416669b 522 SUPERFAMILY SSF53041 28 177 4.71E-38 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS13495 108f52548de4e49acb700a2b7416669b 522 Gene3D G3DSA:3.40.50.1390 24 186 5.1E-47 T 29-03-2018 HVS_RS13495 108f52548de4e49acb700a2b7416669b 522 Pfam PF00239 Resolvase, N terminal domain 29 177 1.5E-35 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS13495 108f52548de4e49acb700a2b7416669b 522 Pfam PF07508 Recombinase 200 307 7.0E-25 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 HVS_RS13495 108f52548de4e49acb700a2b7416669b 522 SMART SM00857 29 178 3.9E-52 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS13495 108f52548de4e49acb700a2b7416669b 522 Pfam PF13408 Recombinase zinc beta ribbon domain 327 387 1.0E-7 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Gene3D G3DSA:3.30.457.10 123 265 1.7E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Gene3D G3DSA:3.30.457.10 18 58 7.2E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Gene3D G3DSA:3.30.457.10 59 122 1.3E-21 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Pfam PF00188 Cysteine-rich secretory protein family 331 444 8.5E-15 T 29-03-2018 IPR014044 CAP domain HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Gene3D G3DSA:3.40.33.10 317 451 5.5E-10 T 29-03-2018 IPR014044 CAP domain HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Pfam PF14504 CAP-associated N-terminal 170 313 2.8E-30 T 29-03-2018 IPR029410 CAP-associated domain HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 SUPERFAMILY SSF55797 322 448 4.01E-17 T 29-03-2018 IPR014044 CAP domain HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 Pfam PF07833 Copper amine oxidase N-terminal domain 48 140 2.2E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08435 cf1b0a0feb4bf4dd601b4f39d1f7b76d 461 SUPERFAMILY SSF55383 50 135 2.35E-22 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13455 fcf07b4d14336dbfbef66ed691b5eb5b 203 SUPERFAMILY SSF53335 109 177 4.32E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13455 fcf07b4d14336dbfbef66ed691b5eb5b 203 Gene3D G3DSA:1.10.10.10 4 97 2.6E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13455 fcf07b4d14336dbfbef66ed691b5eb5b 203 Gene3D G3DSA:3.40.50.720 98 203 6.7E-11 T 29-03-2018 HVS_RS13455 fcf07b4d14336dbfbef66ed691b5eb5b 203 Pfam PF08484 C-methyltransferase C-terminal domain 94 199 1.2E-5 T 29-03-2018 IPR013691 C-methyltransferase HVS_RS13455 fcf07b4d14336dbfbef66ed691b5eb5b 203 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 53 1.8E-7 T 29-03-2018 HVS_RS13455 fcf07b4d14336dbfbef66ed691b5eb5b 203 SUPERFAMILY SSF46785 11 77 5.83E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08830 f040534760ae261c51f138f612e13f38 331 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 5 329 67.749 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS08830 f040534760ae261c51f138f612e13f38 331 SUPERFAMILY SSF53901 7 329 4.07E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08830 f040534760ae261c51f138f612e13f38 331 Gene3D G3DSA:3.40.47.10 166 328 7.8E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08830 f040534760ae261c51f138f612e13f38 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 240 329 5.9E-34 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS08830 f040534760ae261c51f138f612e13f38 331 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 329 5.0E-120 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS08830 f040534760ae261c51f138f612e13f38 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 188 3.3E-30 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS08830 f040534760ae261c51f138f612e13f38 331 Gene3D G3DSA:3.40.47.10 5 165 2.9E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 180 202 1.7E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 1.7E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 213 225 1.7E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 159 174 1.7E-24 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 SUPERFAMILY SSF52374 2 318 1.64E-102 T 29-03-2018 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 Gene3D G3DSA:3.40.50.620 3 220 4.6E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 405 7.1E-134 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 Gene3D G3DSA:3.10.290.10 312 407 5.0E-23 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 406 43.619 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 Pfam PF01479 S4 domain 345 386 4.2E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 Gene3D G3DSA:1.10.240.10 221 311 2.3E-35 T 29-03-2018 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 SUPERFAMILY SSF55174 300 405 6.8E-18 T 29-03-2018 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 Pfam PF00579 tRNA synthetases class I (W and Y) 28 318 1.6E-83 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS08035 5bac0c460fc5cf1d52188880608fec31 407 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS06970 42f58b13f558c3419a6ebc1822169613 549 Pfam PF07691 PA14 domain 201 281 6.4E-6 T 29-03-2018 IPR011658 PA14 domain HVS_RS06970 42f58b13f558c3419a6ebc1822169613 549 Gene3D G3DSA:2.60.40.1080 462 543 7.1E-5 T 29-03-2018 HVS_RS06970 42f58b13f558c3419a6ebc1822169613 549 TIGRFAM TIGR02148 Fibro_Slime: fibro-slime domain 197 286 3.2E-34 T 29-03-2018 IPR011874 Fibro-slime HVS_RS06970 42f58b13f558c3419a6ebc1822169613 549 Gene3D G3DSA:2.60.120.380 132 294 8.7E-6 T 29-03-2018 HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 Hamap MF_01227 CTP synthase [pyrG]. 3 531 52.667 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 Gene3D G3DSA:3.40.50.300 1 287 1.6E-136 T 29-03-2018 HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 SUPERFAMILY SSF52540 3 272 4.69E-126 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 Pfam PF06418 CTP synthase N-terminus 4 268 1.4E-132 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 Gene3D G3DSA:3.40.50.880 288 531 1.7E-77 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 TIGRFAM TIGR00337 PyrG: CTP synthase 2 528 7.4E-264 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 SUPERFAMILY SSF52317 290 530 2.01E-86 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS14220 aae8796f7fa61b9906da24e58928ea6c 531 Pfam PF00117 Glutamine amidotransferase class-I 303 528 1.6E-57 T 29-03-2018 IPR017926 Glutamine amidotransferase HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 Gene3D G3DSA:3.90.1240.10 1 123 3.6E-24 T 29-03-2018 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 Gene3D G3DSA:3.20.80.10 124 288 4.7E-39 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 SMART SM00871 128 288 6.8E-33 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 SUPERFAMILY SSF46689 58 115 1.16E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 SUPERFAMILY SSF46689 5 55 1.12E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 SMART SM00342 21 104 4.7E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 Pfam PF06445 GyrI-like small molecule binding domain 128 288 5.5E-29 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 9.1E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 9.1E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 SUPERFAMILY SSF55136 128 290 1.91E-30 T 29-03-2018 HVS_RS13670 22e87278330ad25f0d087235c77fca03 292 Pfam PF12833 Helix-turn-helix domain 29 104 9.2E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 Gene3D G3DSA:3.90.220.20 3 198 1.1E-36 T 29-03-2018 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 Gene3D G3DSA:3.90.220.20 199 401 2.3E-36 T 29-03-2018 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 SUPERFAMILY SSF116734 7 224 2.78E-46 T 29-03-2018 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 SUPERFAMILY SSF116734 223 445 7.19E-45 T 29-03-2018 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 Gene3D G3DSA:1.10.287.1120 402 503 9.6E-11 T 29-03-2018 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 Pfam PF01420 Type I restriction modification DNA specificity domain 239 418 9.0E-12 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS06590 1ebbcbfec0407e3490b96ecbe780a2ed 514 Pfam PF01420 Type I restriction modification DNA specificity domain 22 200 9.1E-13 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 SUPERFAMILY SSF51735 3 197 9.29E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 SUPERFAMILY SSF48179 205 299 3.27E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 421 2.1E-143 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 SUPERFAMILY SSF52413 306 435 6.02E-36 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 187 3.1E-67 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 424 4.9E-32 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 Gene3D G3DSA:1.20.5.100 206 228 1.2E-15 T 29-03-2018 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 Gene3D G3DSA:3.40.50.720 1 202 7.2E-62 T 29-03-2018 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 Gene3D G3DSA:3.40.50.720 229 437 7.5E-76 T 29-03-2018 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 PIRSF PIRSF500134 2 440 4.9E-180 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 SMART SM00984 320 425 2.1E-41 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 PIRSF PIRSF000124 2 440 5.1E-147 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HVS_RS06155 5957a0027dbcc4bee59ac0c022725681 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 297 1.3E-38 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS07410 ea625bae77dec91509501b041429f2e8 168 SUPERFAMILY SSF55486 5 161 2.1E-40 T 29-03-2018 HVS_RS07410 ea625bae77dec91509501b041429f2e8 168 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 161 22.964 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HVS_RS07410 ea625bae77dec91509501b041429f2e8 168 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 127 137 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site HVS_RS07410 ea625bae77dec91509501b041429f2e8 168 Pfam PF02130 Uncharacterized protein family UPF0054 17 156 2.0E-41 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HVS_RS07410 ea625bae77dec91509501b041429f2e8 168 Gene3D G3DSA:3.40.390.30 1 168 1.0E-44 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 HVS_RS07410 ea625bae77dec91509501b041429f2e8 168 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 157 8.8E-37 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 SUPERFAMILY SSF53067 6 144 1.45E-41 T 29-03-2018 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 183 203 3.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 296 322 3.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 3.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 128 147 3.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 3.0E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 331 1.9E-147 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 Gene3D G3DSA:3.30.420.40 3 155 5.2E-39 T 29-03-2018 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 Gene3D G3DSA:3.30.420.40 156 191 9.1E-5 T 29-03-2018 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 Pfam PF06723 MreB/Mbl protein 6 331 5.7E-148 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 Gene3D G3DSA:3.90.640.10 192 248 4.1E-30 T 29-03-2018 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 Gene3D G3DSA:3.30.420.40 249 313 2.2E-11 T 29-03-2018 HVS_RS15815 02961a4dae20d810df60b63ec5e0ec4a 343 SUPERFAMILY SSF53067 146 328 6.05E-51 T 29-03-2018 HVS_RS07940 5c964d127bc32091301030424b911e43 811 Gene3D G3DSA:2.130.10.10 463 696 1.7E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS07940 5c964d127bc32091301030424b911e43 811 Pfam PF13308 YARHG domain 289 345 1.7E-14 T 29-03-2018 IPR025582 YARHG domain HVS_RS07940 5c964d127bc32091301030424b911e43 811 SMART SM01324 266 346 6.0E-5 T 29-03-2018 IPR025582 YARHG domain HVS_RS07940 5c964d127bc32091301030424b911e43 811 Gene3D G3DSA:3.30.930.10 283 462 0.0018 T 29-03-2018 HVS_RS07940 5c964d127bc32091301030424b911e43 811 SUPERFAMILY SSF82171 608 717 2.94E-7 T 29-03-2018 HVS_RS07940 5c964d127bc32091301030424b911e43 811 SUPERFAMILY SSF82171 464 558 2.94E-7 T 29-03-2018 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 SUPERFAMILY SSF46689 52 109 1.12E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 Pfam PF12833 Helix-turn-helix domain 23 98 8.8E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 Gene3D G3DSA:3.20.80.10 118 282 4.4E-39 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 SUPERFAMILY SSF46689 2 49 9.41E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 SMART SM00871 122 282 6.8E-33 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 Gene3D G3DSA:3.90.1240.10 1 117 3.3E-23 T 29-03-2018 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 SMART SM00342 15 98 4.7E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 67 82 8.8E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 82 98 8.8E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 SUPERFAMILY SSF55136 122 284 1.8E-30 T 29-03-2018 HVS_RS03040 e329d5ccd477f9632d7af9bc59583fa9 286 Pfam PF06445 GyrI-like small molecule binding domain 122 282 5.2E-29 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain HVS_RS06750 3028a4f47b9778f8e8ad5fa07d750720 353 Gene3D G3DSA:1.10.10.60 295 345 7.2E-5 T 29-03-2018 HVS_RS06750 3028a4f47b9778f8e8ad5fa07d750720 353 Pfam PF04754 Putative transposase, YhgA-like 9 211 3.5E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 Pfam PF02018 Carbohydrate binding domain 27 156 3.1E-22 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 Gene3D G3DSA:2.60.120.260 32 183 9.7E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 SUPERFAMILY SSF49785 26 179 2.72E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 Gene3D G3DSA:1.50.10.10 283 782 3.2E-130 T 29-03-2018 HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 Pfam PF02927 Cellulase N-terminal ig-like domain 197 274 2.0E-25 T 29-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 Gene3D G3DSA:2.60.40.10 193 281 9.1E-26 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 Pfam PF00759 Glycosyl hydrolase family 9 285 773 2.8E-104 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 750 768 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 SUPERFAMILY SSF81296 188 280 4.06E-25 T 29-03-2018 IPR014756 Immunoglobulin E-set HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 SUPERFAMILY SSF63446 793 851 1.96E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS11015 9104469078613a04cf5466ffd8e0885a 856 SUPERFAMILY SSF48208 284 779 2.19E-133 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS04095 c25ea44cdb7c3b287da4a633b72ef6bc 254 Pfam PF07591 Pretoxin HINT domain 181 252 2.8E-10 T 29-03-2018 HVS_RS04095 c25ea44cdb7c3b287da4a633b72ef6bc 254 Gene3D G3DSA:2.170.16.10 174 253 7.9E-23 T 29-03-2018 HVS_RS04095 c25ea44cdb7c3b287da4a633b72ef6bc 254 SUPERFAMILY SSF51294 175 252 6.28E-15 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02090 9371b124381d7e9151a4f583e7c6ad20 328 SUPERFAMILY SSF55383 52 135 9.94E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02090 9371b124381d7e9151a4f583e7c6ad20 328 Pfam PF07833 Copper amine oxidase N-terminal domain 51 141 8.2E-32 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02090 9371b124381d7e9151a4f583e7c6ad20 328 Gene3D G3DSA:3.30.457.10 62 122 2.6E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02090 9371b124381d7e9151a4f583e7c6ad20 328 Gene3D G3DSA:3.30.457.10 123 278 1.3E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02090 9371b124381d7e9151a4f583e7c6ad20 328 Gene3D G3DSA:3.30.457.10 9 61 7.4E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 3.5E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 3.5E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 PRINTS PR00834 HtrA/DegQ protease family signature 125 137 3.5E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 PRINTS PR00834 HtrA/DegQ protease family signature 334 346 3.5E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 3.5E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 PRINTS PR00834 HtrA/DegQ protease family signature 187 211 3.5E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 Gene3D G3DSA:2.40.10.10 183 284 4.1E-37 T 29-03-2018 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 Pfam PF13180 PDZ domain 295 384 7.3E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 SMART SM00228 307 376 3.7E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 SUPERFAMILY SSF50494 79 289 4.79E-57 T 29-03-2018 IPR009003 Peptidase S1, PA clan HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 SUPERFAMILY SSF50156 275 384 1.28E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 Gene3D G3DSA:2.40.10.10 75 182 1.9E-27 T 29-03-2018 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 Pfam PF13365 Trypsin-like peptidase domain 116 258 1.4E-32 T 29-03-2018 HVS_RS15365 ae1362bb668fc7658e1f77cf50006d18 395 Gene3D G3DSA:2.30.42.10 294 394 1.4E-19 T 29-03-2018 HVS_RS08145 1c5708b61f2d7edfb19599388285c397 516 Gene3D G3DSA:3.90.226.10 1 255 1.4E-75 T 29-03-2018 HVS_RS08145 1c5708b61f2d7edfb19599388285c397 516 Pfam PF01039 Carboxyl transferase domain 28 514 3.9E-199 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 HVS_RS08145 1c5708b61f2d7edfb19599388285c397 516 SUPERFAMILY SSF52096 9 256 6.26E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS08145 1c5708b61f2d7edfb19599388285c397 516 Gene3D G3DSA:3.90.226.10 256 508 7.9E-75 T 29-03-2018 HVS_RS08145 1c5708b61f2d7edfb19599388285c397 516 SUPERFAMILY SSF52096 225 516 2.62E-92 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 TIGRFAM TIGR01312 XylB: xylulokinase 5 495 7.1E-175 T 29-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 SUPERFAMILY SSF53067 3 249 1.99E-86 T 29-03-2018 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 PIRSF PIRSF000538 1 506 1.1E-173 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 Gene3D G3DSA:3.30.420.40 245 501 3.5E-69 T 29-03-2018 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 247 8.0E-85 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 SUPERFAMILY SSF53067 251 494 2.81E-69 T 29-03-2018 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 Gene3D G3DSA:3.30.420.40 1 244 2.3E-85 T 29-03-2018 HVS_RS02320 c33f963a73568d6653fc64b22f79be17 509 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 452 2.9E-39 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HVS_RS13185 565a76427f532748f71e882947d76af2 111 Pfam PF05521 Phage head-tail joining protein 10 103 1.5E-12 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor HVS_RS00665 278cf93146642936e7c362f860dd7589 199 Gene3D G3DSA:1.10.150.20 9 55 0.0028 T 29-03-2018 HVS_RS00665 278cf93146642936e7c362f860dd7589 199 TIGRFAM TIGR00615 recR: recombination protein RecR 4 197 8.9E-87 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HVS_RS00665 278cf93146642936e7c362f860dd7589 199 Gene3D G3DSA:3.40.1360.10 78 171 1.1E-41 T 29-03-2018 HVS_RS00665 278cf93146642936e7c362f860dd7589 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 111.563 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HVS_RS00665 278cf93146642936e7c362f860dd7589 199 ProSitePatterns PS01300 RecR protein signature. 58 79 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 HVS_RS00665 278cf93146642936e7c362f860dd7589 199 SUPERFAMILY SSF111304 4 199 1.44E-78 T 29-03-2018 IPR023627 Recombination protein RecR HVS_RS00665 278cf93146642936e7c362f860dd7589 199 Pfam PF02132 RecR protein 41 79 2.2E-16 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger HVS_RS00665 278cf93146642936e7c362f860dd7589 199 SMART SM00493 81 166 3.9E-18 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS00665 278cf93146642936e7c362f860dd7589 199 Pfam PF13662 Toprim domain 82 172 5.6E-27 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS05025 52b17b4f5ace7a02fe8018d44a9da3a0 440 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 111 129 2.3E-6 T 29-03-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site HVS_RS05025 52b17b4f5ace7a02fe8018d44a9da3a0 440 SUPERFAMILY SSF160980 12 172 1.7E-9 T 29-03-2018 HVS_RS05025 52b17b4f5ace7a02fe8018d44a9da3a0 440 SUPERFAMILY SSF160980 209 404 1.7E-9 T 29-03-2018 HVS_RS05025 52b17b4f5ace7a02fe8018d44a9da3a0 440 Gene3D G3DSA:3.40.50.10640 1 169 5.2E-31 T 29-03-2018 HVS_RS05025 52b17b4f5ace7a02fe8018d44a9da3a0 440 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 4 400 2.2E-75 T 29-03-2018 IPR019016 CRISPR-associated DxTHG protein HVS_RS05025 52b17b4f5ace7a02fe8018d44a9da3a0 440 TIGRFAM TIGR02221 cas_TM1812: CRISPR-associated protein, TM1812 family 74 191 1.6E-22 T 29-03-2018 IPR011742 CRISPR-associated protein, TM1812 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 SUPERFAMILY SSF53649 314 508 2.01E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 SUPERFAMILY SSF53649 6 77 2.01E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 PIRSF PIRSF001492 1 512 6.7E-212 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 SUPERFAMILY SSF64158 77 308 2.75E-91 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 298 4.5E-91 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 509 1.3E-219 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 Gene3D G3DSA:3.40.1450.10 77 302 1.6E-104 T 29-03-2018 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 Gene3D G3DSA:3.40.720.10 303 509 4.0E-39 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 51.071 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11980 1d93b36b6130b2699c60c2c295f8ea52 512 Pfam PF01676 Metalloenzyme superfamily 6 499 1.9E-76 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 Gene3D G3DSA:3.30.565.10 331 492 2.1E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 491 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 447 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 472 5.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 SMART SM00387 382 494 4.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 SMART SM00304 217 269 2.5E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 491 2.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 SMART SM00388 270 336 2.3E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 Gene3D G3DSA:3.30.450.20 32 191 2.3E-10 T 29-03-2018 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 Pfam PF00672 HAMP domain 218 265 1.2E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 SUPERFAMILY SSF55874 326 490 3.93E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 SUPERFAMILY SSF158472 218 266 3.66E-10 T 29-03-2018 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 SUPERFAMILY SSF47384 253 337 9.02E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 336 1.7E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10915 0ffcf5e70df15eb37528c9f180858d2d 497 Gene3D G3DSA:1.10.287.130 260 330 3.8E-20 T 29-03-2018 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 SUPERFAMILY SSF52935 321 472 1.28E-44 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 SUPERFAMILY SSF51621 1 75 1.26E-102 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 SUPERFAMILY SSF51621 165 342 1.26E-102 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Gene3D G3DSA:3.20.20.60 1 82 1.4E-19 T 29-03-2018 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 469 2.0E-40 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 3.8E-190 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 SUPERFAMILY SSF52009 464 579 2.75E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Gene3D G3DSA:3.40.1380.20 320 472 1.8E-60 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 1.1E-139 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 SUPERFAMILY SSF50800 70 165 1.1E-28 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Gene3D G3DSA:2.40.33.10 83 165 6.1E-30 T 29-03-2018 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 215 241 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 184 198 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 311 327 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 267 291 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 PRINTS PR01050 Pyruvate kinase family signature 292 310 1.0E-74 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Gene3D G3DSA:3.50.30.10 475 581 1.1E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Pfam PF00391 PEP-utilising enzyme, mobile domain 505 574 1.5E-15 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS03300 97fd29fa80be1f422c931e456ed70a77 581 Gene3D G3DSA:3.20.20.60 166 319 3.5E-67 T 29-03-2018 HVS_RS06935 aeab820c99669d2f983bd50e97e14bd9 176 Gene3D G3DSA:3.40.109.10 1 73 2.2E-15 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HVS_RS06935 aeab820c99669d2f983bd50e97e14bd9 176 Pfam PF00881 Nitroreductase family 63 150 2.6E-11 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HVS_RS06935 aeab820c99669d2f983bd50e97e14bd9 176 Pfam PF00881 Nitroreductase family 6 58 1.8E-12 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HVS_RS06935 aeab820c99669d2f983bd50e97e14bd9 176 Gene3D G3DSA:3.40.109.10 74 169 1.3E-17 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HVS_RS06935 aeab820c99669d2f983bd50e97e14bd9 176 SUPERFAMILY SSF55469 2 170 1.7E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HVS_RS15400 c4f85a40809794e6922763f93e16d073 581 Gene3D G3DSA:2.130.10.130 256 529 2.4E-8 T 29-03-2018 HVS_RS15400 c4f85a40809794e6922763f93e16d073 581 SUPERFAMILY SSF69318 103 364 1.2E-13 T 29-03-2018 HVS_RS15400 c4f85a40809794e6922763f93e16d073 581 SUPERFAMILY SSF69318 466 526 1.2E-13 T 29-03-2018 HVS_RS15400 c4f85a40809794e6922763f93e16d073 581 Gene3D G3DSA:2.60.40.10 1 86 1.9E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 231 245 1.6E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 327 339 1.6E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 435 452 1.6E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 377 393 1.6E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 260 270 1.6E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 SUPERFAMILY SSF53335 147 453 5.83E-74 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 Pfam PF01029 NusB family 6 129 7.6E-38 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 Gene3D G3DSA:1.10.940.10 2 135 1.4E-35 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 185 452 1.1E-69 T 29-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 Gene3D G3DSA:3.30.70.1170 173 240 3.1E-14 T 29-03-2018 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 SUPERFAMILY SSF48013 7 157 2.75E-39 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 453 4.2E-124 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 Gene3D G3DSA:3.40.50.150 241 454 4.2E-62 T 29-03-2018 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 166 245 1.3E-7 T 29-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 250 451 5.1E-62 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS07050 8fe0a26f37726e7e9e764365895aadbe 454 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 326 337 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS04990 9c060578d4230dec6f7bbf0e5b73405c 239 PIRSF PIRSF005054 1 239 3.0E-68 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HVS_RS04990 9c060578d4230dec6f7bbf0e5b73405c 239 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 47 237 3.8E-38 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HVS_RS04990 9c060578d4230dec6f7bbf0e5b73405c 239 Pfam PF01881 CRISPR associated protein Cas6 99 238 9.1E-35 T 29-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 Gene3D G3DSA:2.40.50.110 148 217 2.8E-4 T 29-03-2018 HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 Pfam PF07833 Copper amine oxidase N-terminal domain 60 151 2.7E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 SUPERFAMILY SSF51445 527 564 1.78E-38 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 SUPERFAMILY SSF51445 279 466 1.78E-38 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 Gene3D G3DSA:3.20.20.80 218 580 5.3E-45 T 29-03-2018 HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 ProSitePatterns PS01095 Chitinases family 18 active site. 359 367 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 SUPERFAMILY SSF55383 64 145 1.06E-12 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 SMART SM00636 259 555 9.5E-7 T 29-03-2018 IPR011583 Chitinase II GO:0008061 HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 Gene3D G3DSA:3.30.457.10 63 141 2.5E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15215 2755ddb57273f5e2d9d6f32d6073865d 589 Pfam PF00704 Glycosyl hydrolases family 18 332 552 1.4E-24 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 SUPERFAMILY SSF54686 2 136 1.31E-60 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 6.9E-54 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.421 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.7E-62 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.6E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.6E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.6E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.6E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15105 6df120a04b8e8277945b8a745d57394c 145 Gene3D G3DSA:3.90.1170.10 3 139 1.9E-54 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 306 970 1.8E-179 T 29-03-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Gene3D G3DSA:3.40.1110.10 422 603 1.2E-27 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Gene3D G3DSA:2.70.150.10 14 222 2.0E-44 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF81653 124 220 1.7E-26 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Pfam PF00702 haloacid dehalogenase-like hydrolase 389 721 3.6E-20 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF56784 391 411 2.57E-55 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF56784 561 820 2.57E-55 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 707 726 3.3E-41 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 605 616 3.3E-41 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 393 407 3.3E-41 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 627 637 3.3E-41 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 3.3E-41 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 731 743 3.3E-41 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Gene3D G3DSA:1.20.1110.10 728 979 3.8E-56 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Gene3D G3DSA:1.20.1110.10 295 421 1.7E-31 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF81665 222 290 1.44E-35 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF81665 9 122 1.44E-35 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF81665 757 976 1.83E-71 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF81665 298 387 1.83E-71 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Pfam PF00690 Cation transporter/ATPase, N-terminus 10 74 1.9E-19 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Pfam PF00122 E1-E2 ATPase 124 282 4.7E-36 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Pfam PF00122 E1-E2 ATPase 298 372 1.5E-7 T 29-03-2018 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Pfam PF00689 Cation transporting ATPase, C-terminus 800 971 1.2E-39 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 Gene3D G3DSA:3.40.50.1000 604 727 4.2E-18 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SMART SM00831 9 79 2.6E-17 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 395 401 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 707 723 4.2E-14 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 564 582 4.2E-14 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 739 764 4.2E-14 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 SUPERFAMILY SSF81660 399 617 6.32E-40 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 299 417 1.4E-22 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 674 795 1.3E-34 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS07915 a5016d75d8ec0810299e685f81c17ea4 979 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 262 4.8E-22 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 Gene3D G3DSA:3.90.180.10 350 405 2.9E-4 T 29-03-2018 HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 SUPERFAMILY SSF50129 33 213 2.65E-33 T 29-03-2018 IPR011032 GroES-like HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 Pfam PF00107 Zinc-binding dehydrogenase 215 348 6.0E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 Gene3D G3DSA:3.90.180.10 21 208 1.1E-31 T 29-03-2018 HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 SUPERFAMILY SSF51735 181 367 2.92E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 48 174 1.7E-22 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 Gene3D G3DSA:3.40.50.720 209 339 7.1E-17 T 29-03-2018 HVS_RS14540 8ce9afbf27d44f2e4ac5a83f2c056726 405 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 86 100 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 HVS_RS03260 aa558b9d61bb13bd1190b9e8decd1403 344 Gene3D G3DSA:1.10.3470.10 3 344 6.6E-72 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like HVS_RS03260 aa558b9d61bb13bd1190b9e8decd1403 344 SUPERFAMILY SSF81345 8 336 3.01E-74 T 29-03-2018 IPR029022 ABC transporter, BtuC-like HVS_RS03260 aa558b9d61bb13bd1190b9e8decd1403 344 Pfam PF01032 FecCD transport family 18 335 5.8E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 HVS_RS05160 69e2aadeb9f7e8d55698c3b0a1ed830d 323 PIRSF PIRSF036894 2 323 6.7E-104 T 29-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HVS_RS05160 69e2aadeb9f7e8d55698c3b0a1ed830d 323 Gene3D G3DSA:2.60.120.10 1 227 2.1E-62 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS05160 69e2aadeb9f7e8d55698c3b0a1ed830d 323 SUPERFAMILY SSF51182 1 322 1.2E-88 T 29-03-2018 IPR011051 RmlC-like cupin domain HVS_RS05160 69e2aadeb9f7e8d55698c3b0a1ed830d 323 Gene3D G3DSA:2.60.120.10 242 323 7.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS05160 69e2aadeb9f7e8d55698c3b0a1ed830d 323 Pfam PF01238 Phosphomannose isomerase type I 5 109 4.6E-17 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SUPERFAMILY SSF63446 512 578 4.02E-10 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Gene3D G3DSA:2.60.40.10 578 720 0.0023 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SUPERFAMILY SSF52743 35 323 1.17E-71 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF00082 Subtilase family 48 301 1.2E-46 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Gene3D G3DSA:2.60.40.680 338 505 3.9E-17 T 29-03-2018 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF01344 Kelch motif 1086 1121 1.4E-9 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF01344 Kelch motif 1037 1079 1.6E-11 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF01344 Kelch motif 990 1035 3.8E-12 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF01344 Kelch motif 941 978 1.8E-4 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SUPERFAMILY SSF117281 871 1130 9.81E-59 T 29-03-2018 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 3267 3347 4.7E-21 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 53 64 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF05593 RHS Repeat 3074 3112 2.4E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Gene3D G3DSA:2.40.50.110 1250 1324 2.9E-11 T 29-03-2018 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF00963 Cohesin domain 345 464 6.1E-14 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SMART SM00612 1049 1097 1.4E-11 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SMART SM00612 1098 1159 0.6 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SMART SM00612 1002 1048 1.5E-12 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SMART SM00612 953 1001 3.8 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SMART SM00612 905 952 1.6E-5 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3074 3112 2.4E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS01925 b9879dd0428557796c71417275982c16 3657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1754 1790 2.5E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS01925 b9879dd0428557796c71417275982c16 3657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2489 2519 9.5E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS01925 b9879dd0428557796c71417275982c16 3657 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1771 1811 2.2E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Gene3D G3DSA:2.120.10.80 863 981 3.9E-12 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Gene3D G3DSA:2.120.10.80 982 1184 8.3E-43 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Pfam PF11692 Protein of unknown function (DUF3289) 3452 3652 2.3E-23 T 29-03-2018 IPR017483 Conserved hypothetical protein CHP03034 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 266 276 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site HVS_RS01925 b9879dd0428557796c71417275982c16 3657 Gene3D G3DSA:3.40.50.200 4 330 3.5E-83 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 SUPERFAMILY SSF49384 344 450 4.49E-15 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS01925 b9879dd0428557796c71417275982c16 3657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 265 281 4.0E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS01925 b9879dd0428557796c71417275982c16 3657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 110 123 4.0E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS01925 b9879dd0428557796c71417275982c16 3657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 48 67 4.0E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS01925 b9879dd0428557796c71417275982c16 3657 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 114 124 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site HVS_RS12175 3fb33d85ebf47203a87fa3f95bae811c 259 Pfam PF02654 Cobalamin-5-phosphate synthase 15 245 3.6E-49 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS12175 3fb33d85ebf47203a87fa3f95bae811c 259 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 259 37.198 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS12175 3fb33d85ebf47203a87fa3f95bae811c 259 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 9 246 4.9E-43 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 SUPERFAMILY SSF63446 659 738 4.32E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 Pfam PF00942 Cellulose binding domain 494 572 2.0E-12 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 Gene3D G3DSA:1.50.10.10 30 468 2.8E-130 T 29-03-2018 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 387 403 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 SUPERFAMILY SSF48208 29 478 2.33E-157 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 Pfam PF00404 Dockerin type I repeat 665 685 9.4E-7 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 437 455 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 Pfam PF00759 Glycosyl hydrolase family 9 31 461 7.7E-135 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 Gene3D G3DSA:2.60.40.710 485 637 1.8E-36 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 SUPERFAMILY SSF49384 491 638 1.41E-41 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS07085 1ae75c0a77d36c22bc5099969947efb4 739 SMART SM01067 487 573 2.3E-19 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 144 3.1E-11 T 29-03-2018 HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 Pfam PF00183 Hsp90 protein 209 620 2.6E-59 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PRINTS PR00775 90kDa heat shock protein signature 25 47 7.4E-37 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PRINTS PR00775 90kDa heat shock protein signature 74 91 7.4E-37 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PRINTS PR00775 90kDa heat shock protein signature 187 205 7.4E-37 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PRINTS PR00775 90kDa heat shock protein signature 169 186 7.4E-37 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PRINTS PR00775 90kDa heat shock protein signature 92 109 7.4E-37 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PRINTS PR00775 90kDa heat shock protein signature 118 140 7.4E-37 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 SUPERFAMILY SSF55874 4 209 3.93E-57 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 PIRSF PIRSF002583 1 626 7.1E-156 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 Gene3D G3DSA:3.30.565.10 28 219 8.9E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 SUPERFAMILY SSF54211 231 477 3.26E-71 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS06945 07c61127f67deb93ca2e7911610b69c5 628 SUPERFAMILY SSF110942 502 619 4.32E-6 T 29-03-2018 HVS_RS09420 88c09b435b4862a9d782661294be5aa7 173 Gene3D G3DSA:3.40.109.10 1 172 2.6E-49 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HVS_RS09420 88c09b435b4862a9d782661294be5aa7 173 SUPERFAMILY SSF55469 1 171 9.55E-56 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 HVS_RS09420 88c09b435b4862a9d782661294be5aa7 173 Pfam PF00881 Nitroreductase family 8 61 4.8E-15 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 HVS_RS15785 25c1eda00f61a4afeab77c0be9f239f8 124 SUPERFAMILY SSF51735 4 121 2.96E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15785 25c1eda00f61a4afeab77c0be9f239f8 124 Gene3D G3DSA:3.40.50.720 6 123 1.9E-30 T 29-03-2018 HVS_RS15785 25c1eda00f61a4afeab77c0be9f239f8 124 Pfam PF13380 CoA binding domain 10 122 5.7E-34 T 29-03-2018 IPR003781 CoA-binding GO:0048037 HVS_RS15785 25c1eda00f61a4afeab77c0be9f239f8 124 SMART SM00881 6 98 9.6E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 HVS_RS01545 10d82bd7fa548e2f2e3dae578c5764d5 379 SUPERFAMILY SSF116734 4 169 1.49E-40 T 29-03-2018 HVS_RS01545 10d82bd7fa548e2f2e3dae578c5764d5 379 Pfam PF01420 Type I restriction modification DNA specificity domain 4 156 1.1E-22 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS01545 10d82bd7fa548e2f2e3dae578c5764d5 379 SUPERFAMILY SSF116734 176 374 4.25E-28 T 29-03-2018 HVS_RS01545 10d82bd7fa548e2f2e3dae578c5764d5 379 Gene3D G3DSA:3.90.220.20 148 362 2.5E-28 T 29-03-2018 HVS_RS01545 10d82bd7fa548e2f2e3dae578c5764d5 379 Gene3D G3DSA:3.90.220.20 3 147 8.2E-22 T 29-03-2018 HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 175 3.2E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 SUPERFAMILY SSF88946 3 108 8.95E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 Pfam PF08281 Sigma-70, region 4 120 171 3.8E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 SUPERFAMILY SSF88659 107 175 5.98E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 Gene3D G3DSA:1.10.10.10 116 181 9.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 Pfam PF04542 Sigma-70 region 2 23 89 1.2E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12920 8c7fc2a56340bf8ff393e7307836bd12 184 Gene3D G3DSA:1.10.1740.10 2 115 2.6E-24 T 29-03-2018 HVS_RS06645 bf0318b799142a80f397b0b507d39aec 246 Pfam PF01844 HNH endonuclease 171 226 2.3E-8 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 HVS_RS06645 bf0318b799142a80f397b0b507d39aec 246 SMART SM00507 158 222 0.0028 T 29-03-2018 IPR003615 HNH nuclease HVS_RS06645 bf0318b799142a80f397b0b507d39aec 246 Gene3D G3DSA:3.40.1800.10 149 239 4.0E-11 T 29-03-2018 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 389 7.0E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 SUPERFAMILY SSF56601 9 299 3.49E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 SMART SM00936 299 389 1.8E-24 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 Gene3D G3DSA:3.40.710.10 43 298 4.1E-48 T 29-03-2018 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 137 154 3.8E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 84 95 3.8E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 164 177 3.8E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 SUPERFAMILY SSF69189 299 390 5.89E-17 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 55 278 1.7E-80 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS09505 2636b8bac13ab4cba341fd0cc6190c69 411 Gene3D G3DSA:2.60.410.10 299 389 1.1E-20 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 Pfam PF01048 Phosphorylase superfamily 25 270 4.9E-56 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 PIRSF PIRSF000477 2 273 2.6E-109 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 271 1.1E-105 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 24 270 7.1E-105 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 SUPERFAMILY SSF53167 4 271 1.57E-93 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 Gene3D G3DSA:3.40.50.1580 2 273 3.7E-69 T 29-03-2018 HVS_RS12250 fef7c5ade596b237d016bf4aa467838d 275 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 77 118 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PIRSF PIRSF001400 3 428 1.1E-196 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 427 6.9E-215 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 SMART SM01193 7 137 2.2E-99 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 Hamap MF_00318 Enolase [eno]. 5 415 45.699 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 ProSitePatterns PS00164 Enolase signature. 338 351 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PRINTS PR00148 Enolase signature 338 352 1.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PRINTS PR00148 Enolase signature 110 126 1.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PRINTS PR00148 Enolase signature 40 54 1.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PRINTS PR00148 Enolase signature 164 177 1.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PRINTS PR00148 Enolase signature 315 326 1.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 PRINTS PR00148 Enolase signature 367 384 1.4E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 426 4.8E-133 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 SUPERFAMILY SSF54826 7 140 1.19E-58 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 Pfam PF03952 Enolase, N-terminal domain 7 137 2.3E-61 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 Gene3D G3DSA:3.30.390.10 6 129 4.3E-55 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 SUPERFAMILY SSF51604 142 429 3.54E-131 T 29-03-2018 IPR029065 Enolase C-terminal domain-like HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 SMART SM01192 142 429 6.5E-221 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS11640 ca170c0d59429f49f302779129a79ea5 433 Gene3D G3DSA:3.20.20.120 131 433 3.5E-108 T 29-03-2018 IPR029065 Enolase C-terminal domain-like HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Pfam PF09334 tRNA synthetases class I (M) 138 361 7.0E-70 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 509 50.894 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 3.8E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.8E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 3.8E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 3.8E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 3.8E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.8E-31 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 5 133 1.0E-12 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Pfam PF08264 Anticodon-binding domain of tRNA 395 531 2.9E-13 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 519 651 1.5E-44 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 SUPERFAMILY SSF52374 3 348 2.42E-118 T 29-03-2018 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Gene3D G3DSA:2.40.50.140 543 651 2.5E-32 T 29-03-2018 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Gene3D G3DSA:3.40.50.620 3 345 5.7E-106 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 SUPERFAMILY SSF47323 351 564 3.27E-51 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 SUPERFAMILY SSF50249 550 650 2.94E-35 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Gene3D G3DSA:1.10.730.10 346 512 1.5E-46 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 139 511 1.0E-119 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HVS_RS14595 1fcf5297da8316709667b7bc2d168c1c 651 Pfam PF01588 Putative tRNA binding domain 557 648 2.4E-29 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 HVS_RS10340 bf92aa86820efab5bf77d5fc53177997 120 PIRSF PIRSF018579 1 112 3.0E-42 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 HVS_RS10340 bf92aa86820efab5bf77d5fc53177997 120 Pfam PF06947 Protein of unknown function (DUF1290) 21 106 5.5E-36 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 HVS_RS10035 da7a16580360b9e2122227f33d6fadd2 452 Pfam PF05167 Uncharacterised ACR (DUF711) 13 416 2.3E-187 T 29-03-2018 IPR007841 Uncharacterised protein family UPF0210 HVS_RS10035 da7a16580360b9e2122227f33d6fadd2 452 Gene3D G3DSA:3.20.70.20 14 429 6.5E-189 T 29-03-2018 HVS_RS10035 da7a16580360b9e2122227f33d6fadd2 452 Hamap MF_01221 UPF0210 protein . 2 452 53.998 T 29-03-2018 IPR007841 Uncharacterised protein family UPF0210 HVS_RS10035 da7a16580360b9e2122227f33d6fadd2 452 SUPERFAMILY SSF51998 4 447 1.65E-186 T 29-03-2018 HVS_RS11545 2ef1ccc174b05686ba163babf116a752 97 Gene3D G3DSA:3.30.110.60 1 94 4.4E-27 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HVS_RS11545 2ef1ccc174b05686ba163babf116a752 97 SMART SM01103 2 85 9.5E-39 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HVS_RS11545 2ef1ccc174b05686ba163babf116a752 97 SUPERFAMILY SSF75471 1 94 3.14E-29 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HVS_RS11545 2ef1ccc174b05686ba163babf116a752 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 3.8E-22 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HVS_RS11545 2ef1ccc174b05686ba163babf116a752 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 95 2.0E-31 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 HVS_RS11545 2ef1ccc174b05686ba163babf116a752 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 95 2.8E-31 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 449 458 - T 29-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 Pfam PF00270 DEAD/DEAH box helicase 321 495 1.8E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 Gene3D G3DSA:3.40.50.300 526 1071 2.2E-31 T 29-03-2018 HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 Gene3D G3DSA:3.40.50.300 134 508 2.2E-20 T 29-03-2018 HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 SUPERFAMILY SSF52540 371 677 5.4E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 SMART SM00487 313 534 7.8E-22 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 Pfam PF00271 Helicase conserved C-terminal domain 547 656 3.3E-19 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS06580 f670d4c18bb1d36ed8a0d5107e310001 1075 SMART SM00490 575 657 5.9E-20 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Pfam PF13375 RnfC Barrel sandwich hybrid domain 6 103 6.9E-33 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 125 270 3.0E-50 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 402 413 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Gene3D G3DSA:3.30.70.20 281 373 2.2E-5 T 29-03-2018 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 6 431 5.5E-155 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 SUPERFAMILY SSF46548 321 432 1.96E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Pfam PF13237 4Fe-4S dicluster domain 362 413 1.5E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Pfam PF10531 SLBB domain 283 332 2.1E-15 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 SUPERFAMILY SSF142019 84 290 4.18E-55 T 29-03-2018 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Gene3D G3DSA:3.30.70.20 374 404 2.3E-10 T 29-03-2018 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 437 138.246 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 HVS_RS01670 89596de0ce41aae089c36777e1b8b5a6 437 Gene3D G3DSA:3.30.70.20 405 428 0.0083 T 29-03-2018 HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 SUPERFAMILY SSF49303 736 800 1.29E-13 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Gene3D G3DSA:2.60.40.10 632 728 1.8E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Gene3D G3DSA:3.20.20.80 290 631 8.7E-90 T 29-03-2018 HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 58 126 3.7E-9 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 SUPERFAMILY SSF49303 190 290 5.28E-21 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 SUPERFAMILY SSF51445 288 633 4.97E-115 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 SUPERFAMILY SSF49785 2 184 3.26E-53 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Gene3D G3DSA:2.60.120.260 2 182 4.7E-40 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Gene3D G3DSA:2.60.40.10 731 821 1.6E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Pfam PF00703 Glycosyl hydrolases family 2 190 291 1.0E-12 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 HVS_RS15810 3c48039ae7b15187b4556ba9ccec9184 823 Gene3D G3DSA:2.60.40.10 183 289 1.3E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 SUPERFAMILY SSF56553 50 171 3.14E-44 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 6.2E-28 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 311 2.2E-123 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.904 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 SMART SM00662 20 227 2.1E-102 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 290 2.0E-13 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 8.3E-26 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Gene3D G3DSA:3.30.1360.10 1 86 5.5E-21 T 29-03-2018 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Gene3D G3DSA:1.10.150.20 241 315 2.3E-27 T 29-03-2018 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 SUPERFAMILY SSF55257 5 50 2.75E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 SUPERFAMILY SSF55257 172 226 2.75E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Gene3D G3DSA:3.30.1360.10 123 224 1.1E-29 T 29-03-2018 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 SUPERFAMILY SSF47789 247 311 2.22E-24 T 29-03-2018 HVS_RS14995 da7cc338f4715dfdd2a671ef5da3493d 315 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 2.1E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 SUPERFAMILY SSF56059 11 267 7.51E-49 T 29-03-2018 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 Gene3D G3DSA:3.30.470.20 134 241 1.3E-19 T 29-03-2018 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 Gene3D G3DSA:3.50.30.10 701 806 1.2E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 Pfam PF00391 PEP-utilising enzyme, mobile domain 730 798 5.9E-19 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 50 182 4.9E-31 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 Gene3D G3DSA:3.30.1490.20 42 133 5.5E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 Gene3D G3DSA:3.30.1490.20 1 41 0.018 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS00365 ed946833362feecc25c46226d99f09b5 806 SUPERFAMILY SSF52009 693 802 1.83E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS14005 ea96b09b3a046f5900118bfd03bf1269 92 Pfam PF09869 Uncharacterized protein conserved in archaea (DUF2096) 16 88 2.8E-5 T 29-03-2018 IPR017098 Uncharacterised conserved protein UCP037052 HVS_RS14005 ea96b09b3a046f5900118bfd03bf1269 92 SUPERFAMILY SSF47598 4 47 2.45E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 HVS_RS14005 ea96b09b3a046f5900118bfd03bf1269 92 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 43 3.6E-7 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 HVS_RS14005 ea96b09b3a046f5900118bfd03bf1269 92 Gene3D G3DSA:1.10.1220.10 4 55 7.9E-12 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 HVS_RS15090 92fa5b9c2a4c9218f97cd674f61807b7 122 SMART SM01374 1 122 2.9E-87 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HVS_RS15090 92fa5b9c2a4c9218f97cd674f61807b7 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 8.3E-56 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HVS_RS15090 92fa5b9c2a4c9218f97cd674f61807b7 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.711 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HVS_RS15090 92fa5b9c2a4c9218f97cd674f61807b7 122 SUPERFAMILY SSF50193 1 122 5.1E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HVS_RS15090 92fa5b9c2a4c9218f97cd674f61807b7 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.1E-58 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 HVS_RS15090 92fa5b9c2a4c9218f97cd674f61807b7 122 Gene3D G3DSA:2.40.150.20 1 122 1.4E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HVS_RS07790 087d5348bd5d9ca58e939cafac42248d 95 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 22 92 1.5E-16 T 29-03-2018 IPR002767 Thiamine-binding protein HVS_RS07790 087d5348bd5d9ca58e939cafac42248d 95 Pfam PF01910 Thiamine-binding protein 6 94 8.7E-31 T 29-03-2018 IPR002767 Thiamine-binding protein HVS_RS07790 087d5348bd5d9ca58e939cafac42248d 95 SUPERFAMILY SSF89957 2 95 7.33E-30 T 29-03-2018 IPR029756 MTH1187/YkoF-like HVS_RS07790 087d5348bd5d9ca58e939cafac42248d 95 Gene3D G3DSA:3.30.70.930 1 95 1.8E-25 T 29-03-2018 IPR029756 MTH1187/YkoF-like HVS_RS03940 50528d4fc5d633223e22036ab7873756 190 SUPERFAMILY SSF48371 34 187 1.78E-10 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 HVS_RS03940 50528d4fc5d633223e22036ab7873756 190 Gene3D G3DSA:1.25.10.10 8 190 9.5E-8 T 29-03-2018 IPR011989 Armadillo-like helical HVS_RS03940 50528d4fc5d633223e22036ab7873756 190 Pfam PF13646 HEAT repeats 71 144 1.2E-6 T 29-03-2018 HVS_RS14215 df4326b871ce4140248a13034be0d295 229 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 36 161 2.6E-50 T 29-03-2018 IPR014202 Sporulation stage II, protein R HVS_RS14215 df4326b871ce4140248a13034be0d295 229 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 8 166 5.5E-59 T 29-03-2018 IPR014202 Sporulation stage II, protein R HVS_RS13745 388cc36525b5997ed435fa5ac502e121 287 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 13 281 8.9E-100 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 HVS_RS13745 388cc36525b5997ed435fa5ac502e121 287 Pfam PF02219 Methylenetetrahydrofolate reductase 9 281 2.1E-81 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HVS_RS13745 388cc36525b5997ed435fa5ac502e121 287 SUPERFAMILY SSF51730 10 282 8.83E-90 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like HVS_RS13745 388cc36525b5997ed435fa5ac502e121 287 Gene3D G3DSA:3.20.20.220 2 285 7.7E-89 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like HVS_RS01205 814b1cc77b398534eea4814f1dfab7d8 287 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 14 272 3.5E-47 T 29-03-2018 IPR017039 Virulence factor BrkB HVS_RS01205 814b1cc77b398534eea4814f1dfab7d8 287 PIRSF PIRSF035875 5 287 3.0E-74 T 29-03-2018 IPR017039 Virulence factor BrkB HVS_RS01205 814b1cc77b398534eea4814f1dfab7d8 287 Pfam PF03631 Virulence factor BrkB 23 272 1.5E-66 T 29-03-2018 IPR017039 Virulence factor BrkB HVS_RS02345 f542c9083df736df26e1494098a58684 185 ProSitePatterns PS00856 Guanylate kinase-like signature. 34 51 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HVS_RS02345 f542c9083df736df26e1494098a58684 185 Pfam PF00625 Guanylate kinase 2 176 4.8E-39 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HVS_RS02345 f542c9083df736df26e1494098a58684 185 Gene3D G3DSA:3.40.50.300 1 179 9.7E-54 T 29-03-2018 HVS_RS02345 f542c9083df736df26e1494098a58684 185 SMART SM00072 1 178 3.1E-37 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HVS_RS02345 f542c9083df736df26e1494098a58684 185 SUPERFAMILY SSF52540 2 180 3.02E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02345 f542c9083df736df26e1494098a58684 185 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 2 175 3.4E-56 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 HVS_RS13105 9cb408a7280e07135dd7bb6959625519 147 Pfam PF02018 Carbohydrate binding domain 38 146 1.4E-10 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS13105 9cb408a7280e07135dd7bb6959625519 147 Gene3D G3DSA:2.60.120.260 37 147 3.4E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS13105 9cb408a7280e07135dd7bb6959625519 147 SUPERFAMILY SSF49785 38 144 1.62E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS13215 107743c8cb71653e58e019f7f3ad836b 49 Pfam PF16468 Domain of unknown function (DUF5049) 1 48 4.8E-26 T 29-03-2018 IPR032488 Protein of unknown function DUF5049 HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Gene3D G3DSA:2.60.40.10 570 669 4.5E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 396 537 8.9E-18 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Gene3D G3DSA:2.60.40.10 672 746 0.36 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 SUPERFAMILY SSF55486 233 533 2.93E-26 T 29-03-2018 HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 99 138 2.2E-4 T 29-03-2018 IPR011096 FTP domain HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 SUPERFAMILY SSF49265 564 662 2.08E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Gene3D G3DSA:1.10.390.10 396 569 2.6E-18 T 29-03-2018 HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Gene3D G3DSA:3.10.170.10 214 394 1.2E-11 T 29-03-2018 HVS_RS05580 15e06791fb8cb05d2f580c66e93978cc 751 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 237 390 7.2E-9 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF48452 866 1060 1.06E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:3.30.450.40 1651 1808 1.8E-4 T 29-03-2018 IPR029016 GAF domain-like HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:1.25.40.10 677 864 6.8E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:1.25.40.10 1100 1239 3.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:1.10.510.10 112 305 6.0E-24 T 29-03-2018 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Pfam PF13424 Tetratricopeptide repeat 747 817 1.5E-9 T 29-03-2018 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Pfam PF13424 Tetratricopeptide repeat 866 936 1.4E-10 T 29-03-2018 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1474 1628 1.8E-44 T 29-03-2018 IPR000160 GGDEF domain HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Pfam PF00069 Protein kinase domain 31 260 4.1E-20 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:3.30.450.40 1314 1468 0.023 T 29-03-2018 IPR029016 GAF domain-like HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Pfam PF13191 AAA ATPase domain 292 465 1.4E-16 T 29-03-2018 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1471 1631 1.7E-49 T 29-03-2018 IPR000160 GGDEF domain HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00220 8 277 1.5E-10 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF52540 286 547 5.69E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF48452 696 871 5.22E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:1.25.40.10 865 1078 6.3E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF56112 4 275 1.35E-37 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:3.40.50.300 306 494 1.0E-9 T 29-03-2018 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:3.30.70.270 1469 1648 1.1E-53 T 29-03-2018 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF55781 1319 1469 5.61E-7 T 29-03-2018 IPR029016 GAF domain-like HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00267 1462 1632 3.8E-56 T 29-03-2018 IPR000160 GGDEF domain HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF48452 1097 1215 3.64E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF55073 1478 1634 5.57E-45 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SUPERFAMILY SSF55781 1663 1808 4.77E-8 T 29-03-2018 IPR029016 GAF domain-like HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 746 779 0.003 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 786 819 8.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 1110 1143 220.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 1186 1219 52.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 947 980 0.34 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 866 899 0.0017 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 SMART SM00028 906 940 22.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14485 bcff12984c2e8cd19de54aec84cefbcb 1811 Gene3D G3DSA:3.30.200.20 2 111 1.0E-7 T 29-03-2018 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Pfam PF11490 DNA polymerase III polC-type N-terminus II 88 197 5.3E-17 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Gene3D G3DSA:3.20.20.140 568 784 1.3E-33 T 29-03-2018 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Gene3D G3DSA:2.40.50.140 216 313 1.3E-17 T 29-03-2018 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Gene3D G3DSA:1.10.150.280 1314 1419 3.0E-4 T 29-03-2018 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 412 626 6.6E-44 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1426 398.272 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Gene3D G3DSA:3.30.420.10 407 549 1.2E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Pfam PF14579 Helix-hairpin-helix motif 1337 1418 5.5E-14 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 225 1425 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 SMART SM00479 412 577 2.0E-58 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Pfam PF14480 DNA polymerase III polC-type N-terminus I 3 65 4.5E-11 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 813 1233 2.0E-92 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Pfam PF00929 Exonuclease 414 567 3.3E-43 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 SMART SM00481 328 395 1.4E-26 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 SUPERFAMILY SSF53098 412 866 5.61E-110 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Gene3D G3DSA:3.20.20.150 314 406 2.8E-4 T 29-03-2018 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Pfam PF02811 PHP domain 329 685 2.1E-52 T 29-03-2018 IPR004013 PHP domain GO:0003824 HVS_RS10545 09b0c32f98629fbe206de0fa8c4563ee 1426 Gene3D G3DSA:1.20.5.140 553 567 1.3E-9 T 29-03-2018 HVS_RS00655 24272020a43e2821ff7643954d567415 554 SUPERFAMILY SSF48019 244 359 2.55E-13 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HVS_RS00655 24272020a43e2821ff7643954d567415 554 Gene3D G3DSA:1.10.8.60 167 242 2.2E-19 T 29-03-2018 HVS_RS00655 24272020a43e2821ff7643954d567415 554 SUPERFAMILY SSF52540 31 221 1.08E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00655 24272020a43e2821ff7643954d567415 554 Gene3D G3DSA:3.40.50.300 1 166 5.3E-39 T 29-03-2018 HVS_RS00655 24272020a43e2821ff7643954d567415 554 SMART SM00382 37 179 1.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS00655 24272020a43e2821ff7643954d567415 554 Gene3D G3DSA:1.20.272.10 243 363 2.6E-17 T 29-03-2018 HVS_RS00655 24272020a43e2821ff7643954d567415 554 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 3.5E-137 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 HVS_RS00655 24272020a43e2821ff7643954d567415 554 Pfam PF13177 DNA polymerase III, delta subunit 21 178 1.7E-44 T 29-03-2018 HVS_RS05370 b748b725603290f95a4db813e30f3f63 196 Pfam PF02545 Maf-like protein 2 190 1.2E-58 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 HVS_RS05370 b748b725603290f95a4db813e30f3f63 196 Gene3D G3DSA:3.90.950.10 1 191 1.4E-66 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HVS_RS05370 b748b725603290f95a4db813e30f3f63 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 189 5.1E-54 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 HVS_RS05370 b748b725603290f95a4db813e30f3f63 196 SUPERFAMILY SSF52972 2 190 2.42E-58 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HVS_RS05370 b748b725603290f95a4db813e30f3f63 196 Hamap MF_00528 Septum formation protein Maf [maf]. 2 195 30.298 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 HVS_RS05370 b748b725603290f95a4db813e30f3f63 196 PIRSF PIRSF006305 1 196 8.6E-55 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 SUPERFAMILY SSF53067 196 368 3.52E-34 T 29-03-2018 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 Pfam PF02491 SHS2 domain inserted in FTSA 80 158 1.7E-19 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 Gene3D G3DSA:3.30.420.150 195 392 2.2E-20 T 29-03-2018 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 SUPERFAMILY SSF53067 4 193 1.17E-42 T 29-03-2018 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 Hamap MF_02033 Cell division protein FtsA [ftsA]. 1 411 24.38 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 5 371 9.1E-91 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 Pfam PF14450 Cell division protein FtsA 204 367 1.6E-18 T 29-03-2018 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 Gene3D G3DSA:3.30.420.40 2 184 2.6E-25 T 29-03-2018 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 PIRSF PIRSF003101 1 411 1.8E-119 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 HVS_RS10335 dee726c586612c87228e29b9f42ba1ae 411 SMART SM00842 5 193 5.8E-65 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 Gene3D G3DSA:3.40.50.300 69 354 2.1E-89 T 29-03-2018 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 14 434 2.3E-192 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 1.2E-76 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 23 433 6.3E-204 T 29-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 SMART SM00382 157 338 9.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 88 8.2E-10 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 SUPERFAMILY SSF52540 92 359 9.28E-101 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10245 1d0a2b628cb0d1c5b90d49e88629f6e9 435 TIGRFAM TIGR02546 III_secr_ATP: type III secretion apparatus H+-transporting two-sector ATPase 20 433 1.4E-184 T 29-03-2018 IPR013380 ATPase, type III secretion system, H+-transporting GO:0005524|GO:0005737|GO:0006754|GO:0030254|GO:0030257|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 Hamap MF_01151 Protein GrpE [grpE]. 3 211 18.638 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 Pfam PF01025 GrpE 49 210 6.0E-48 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 Gene3D G3DSA:2.30.22.10 156 211 1.6E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 PRINTS PR00773 GrpE protein signature 81 97 1.2E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 PRINTS PR00773 GrpE protein signature 163 178 1.2E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 PRINTS PR00773 GrpE protein signature 190 209 1.2E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 PRINTS PR00773 GrpE protein signature 109 124 1.2E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 Gene3D G3DSA:3.90.20.20 3 154 2.5E-19 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 ProSitePatterns PS01071 grpE protein signature. 166 209 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 SUPERFAMILY SSF51064 156 210 6.93E-16 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 HVS_RS11110 a9148fe454d545cb59cc10cc5f12f058 211 SUPERFAMILY SSF58014 58 153 2.22E-23 T 29-03-2018 HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 SMART SM00842 11 175 0.0022 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 SUPERFAMILY SSF53067 201 344 2.27E-19 T 29-03-2018 HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 Pfam PF11104 Type IV pilus assembly protein PilM; 14 339 4.4E-36 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 PIRSF PIRSF019169 1 368 3.5E-91 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 SUPERFAMILY SSF53067 12 170 7.12E-10 T 29-03-2018 HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 Gene3D G3DSA:3.30.420.40 201 339 2.2E-11 T 29-03-2018 HVS_RS14500 276f7601c2ac2c2776a47cbc96adfd9f 368 Gene3D G3DSA:3.30.420.40 6 171 2.9E-24 T 29-03-2018 HVS_RS05765 0141097874e1bd784f3f388e4e69df25 287 SUPERFAMILY SSF55383 56 139 1.57E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05765 0141097874e1bd784f3f388e4e69df25 287 Gene3D G3DSA:3.30.457.10 128 254 1.2E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05765 0141097874e1bd784f3f388e4e69df25 287 Gene3D G3DSA:3.30.457.10 66 127 1.6E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05765 0141097874e1bd784f3f388e4e69df25 287 Gene3D G3DSA:3.30.457.10 20 65 2.8E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05765 0141097874e1bd784f3f388e4e69df25 287 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 2.9E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS00585 6b227444bd6a4f782d384d7639a065fa 141 SMART SM00316 4 74 2.6E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS00585 6b227444bd6a4f782d384d7639a065fa 141 SUPERFAMILY SSF50249 4 81 5.07E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS00585 6b227444bd6a4f782d384d7639a065fa 141 Pfam PF00575 S1 RNA binding domain 3 74 1.4E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS00585 6b227444bd6a4f782d384d7639a065fa 141 Gene3D G3DSA:2.40.50.140 1 80 3.6E-26 T 29-03-2018 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SMART SM00388 297 362 9.6E-26 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SUPERFAMILY SSF47384 281 364 1.9E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 141 9.2E-17 T 29-03-2018 IPR000014 PAS domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Gene3D G3DSA:3.40.50.2300 540 749 1.5E-44 T 29-03-2018 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Gene3D G3DSA:3.30.450.20 1 140 6.1E-23 T 29-03-2018 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Pfam PF00072 Response regulator receiver domain 550 663 1.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SMART SM00387 409 525 8.5E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Pfam PF13426 PAS domain 157 275 5.5E-4 T 29-03-2018 IPR000014 PAS domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SUPERFAMILY SSF55785 130 262 2.47E-9 T 29-03-2018 IPR000014 PAS domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 522 9.4E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Gene3D G3DSA:3.30.565.10 366 534 5.2E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Gene3D G3DSA:1.10.287.130 297 358 2.4E-22 T 29-03-2018 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SMART SM00448 548 663 2.3E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SUPERFAMILY SSF52172 546 671 1.27E-39 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Pfam PF00512 His Kinase A (phospho-acceptor) domain 297 362 3.4E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Gene3D G3DSA:3.30.450.20 141 296 2.9E-15 T 29-03-2018 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 Pfam PF00989 PAS fold 20 131 1.6E-14 T 29-03-2018 IPR013767 PAS fold GO:0006355 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SMART SM00091 15 80 4.5E-6 T 29-03-2018 IPR000014 PAS domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SMART SM00091 146 212 9.0 T 29-03-2018 IPR000014 PAS domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 1.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 464 1.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 478 1.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 1.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SUPERFAMILY SSF55874 351 520 1.02E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09670 71d4e00b47c57f50512dcc8db91a24af 783 SUPERFAMILY SSF55785 26 141 1.33E-17 T 29-03-2018 IPR000014 PAS domain HVS_RS08135 32a61b019ce6a91e5e8fba5227bb1f99 463 SUPERFAMILY SSF51569 3 277 1.03E-91 T 29-03-2018 HVS_RS08135 32a61b019ce6a91e5e8fba5227bb1f99 463 SUPERFAMILY SSF89000 297 446 1.41E-54 T 29-03-2018 HVS_RS08135 32a61b019ce6a91e5e8fba5227bb1f99 463 Pfam PF00682 HMGL-like 3 267 7.3E-51 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HVS_RS08135 32a61b019ce6a91e5e8fba5227bb1f99 463 Gene3D G3DSA:1.10.10.60 399 448 6.8E-14 T 29-03-2018 HVS_RS08135 32a61b019ce6a91e5e8fba5227bb1f99 463 Pfam PF02436 Conserved carboxylase domain 294 445 9.0E-58 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 HVS_RS08135 32a61b019ce6a91e5e8fba5227bb1f99 463 Gene3D G3DSA:3.20.20.70 2 278 1.3E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 204 1.5E-58 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 SMART SM00977 388 460 2.1E-23 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 Gene3D G3DSA:3.40.50.620 17 257 2.2E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 SUPERFAMILY SSF56037 377 458 5.89E-23 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 SUPERFAMILY SSF82829 213 321 6.28E-15 T 29-03-2018 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 Gene3D G3DSA:3.50.40.10 349 460 5.0E-14 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 SUPERFAMILY SSF52402 2 208 1.48E-55 T 29-03-2018 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 388 433 3.1E-12 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 Pfam PF01171 PP-loop family 21 199 8.5E-53 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 Pfam PF11734 TilS substrate C-terminal domain 389 457 3.5E-16 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HVS_RS01320 11ec2ff5da1d4a8403bd9b15e8e67c54 467 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 2 315 23.411 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 297 308 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 Gene3D G3DSA:3.20.20.100 1 248 5.8E-36 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 Gene3D G3DSA:3.30.70.20 276 314 1.1E-10 T 29-03-2018 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 PRINTS PR00069 Aldo-keto reductase signature 127 144 4.5E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.5E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 PRINTS PR00069 Aldo-keto reductase signature 42 66 4.5E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 Gene3D G3DSA:3.30.70.20 249 275 5.0E-5 T 29-03-2018 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 SUPERFAMILY SSF54862 255 314 4.19E-14 T 29-03-2018 HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 SUPERFAMILY SSF51430 2 271 2.62E-42 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 Pfam PF00037 4Fe-4S binding domain 294 313 8.0E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS11600 3f0a81cbea8787a0138d62ea0d041eee 315 Pfam PF00248 Aldo/keto reductase family 16 211 2.5E-23 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 Gene3D G3DSA:1.10.1580.10 180 273 1.6E-22 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 3.7E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 3.7E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 Gene3D G3DSA:3.40.50.300 12 179 1.6E-34 T 29-03-2018 HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 279 9.8E-111 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 PIRSF PIRSF006230 1 284 2.1E-102 T 29-03-2018 IPR016478 GTPase, MTG1 HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 SUPERFAMILY SSF52540 9 263 1.96E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09225 c7db238904f886022b4a38ef85eb1298 287 Pfam PF01926 50S ribosome-binding GTPase 123 205 9.7E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS14820 598b089fd86909426bc94fd42dfbed91 132 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 119 2.6E-34 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS14820 598b089fd86909426bc94fd42dfbed91 132 Gene3D G3DSA:1.20.120.340 1 122 1.9E-39 T 29-03-2018 HVS_RS14820 598b089fd86909426bc94fd42dfbed91 132 PIRSF PIRSF039090 1 129 5.6E-34 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS14820 598b089fd86909426bc94fd42dfbed91 132 SUPERFAMILY SSF101116 4 124 4.84E-37 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS14820 598b089fd86909426bc94fd42dfbed91 132 Pfam PF02561 Flagellar protein FliS 8 119 6.2E-37 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS06005 598b089fd86909426bc94fd42dfbed91 132 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 119 2.6E-34 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS06005 598b089fd86909426bc94fd42dfbed91 132 Gene3D G3DSA:1.20.120.340 1 122 1.9E-39 T 29-03-2018 HVS_RS06005 598b089fd86909426bc94fd42dfbed91 132 PIRSF PIRSF039090 1 129 5.6E-34 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS06005 598b089fd86909426bc94fd42dfbed91 132 SUPERFAMILY SSF101116 4 124 4.84E-37 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS06005 598b089fd86909426bc94fd42dfbed91 132 Pfam PF02561 Flagellar protein FliS 8 119 6.2E-37 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 Gene3D G3DSA:3.30.590.10 175 595 4.1E-86 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 SUPERFAMILY SSF55931 441 583 1.18E-75 T 29-03-2018 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 SUPERFAMILY SSF55931 162 396 1.18E-75 T 29-03-2018 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 Pfam PF12437 Glutamine synthetase type III N terminal 13 171 2.4E-80 T 29-03-2018 IPR022147 Glutamine synthetase type III N-terminal GO:0004356 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 SMART SM01230 172 459 7.4E-52 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 317 332 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 HVS_RS07650 5147b9ce6c9ff291d2eeab5b81e670e6 707 Pfam PF00120 Glutamine synthetase, catalytic domain 192 362 6.6E-19 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 SUPERFAMILY SSF52467 184 350 2.46E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 169 1.2E-56 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 SUPERFAMILY SSF52518 363 541 2.86E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 536 1.1E-221 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 SUPERFAMILY SSF52518 1 178 4.29E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 386 533 2.9E-44 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 Gene3D G3DSA:3.40.50.970 341 541 1.7E-48 T 29-03-2018 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 327 6.1E-48 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 Gene3D G3DSA:3.40.50.970 1 186 2.9E-61 T 29-03-2018 HVS_RS01140 f0700a106bc8838433afdf8d30f8b637 542 Gene3D G3DSA:3.40.50.1220 187 340 1.7E-52 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 129 139 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 Gene3D G3DSA:2.60.120.180 28 191 7.3E-61 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 SUPERFAMILY SSF49899 41 181 8.82E-57 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 PRINTS PR00911 Glycosyl hydrolase family 11 signature 119 128 1.7E-8 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 PRINTS PR00911 Glycosyl hydrolase family 11 signature 156 162 1.7E-8 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 PRINTS PR00911 Glycosyl hydrolase family 11 signature 129 139 1.7E-8 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09780 e74b68dc2e2afc137d3675bf29d0e948 194 Pfam PF00457 Glycosyl hydrolases family 11 51 186 3.4E-44 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS04240 ef20d263924fe304897a395435237cab 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS04240 ef20d263924fe304897a395435237cab 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04240 ef20d263924fe304897a395435237cab 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04240 ef20d263924fe304897a395435237cab 266 SUPERFAMILY SSF52540 15 259 4.06E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05650 ef20d263924fe304897a395435237cab 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS05650 ef20d263924fe304897a395435237cab 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS05650 ef20d263924fe304897a395435237cab 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS05650 ef20d263924fe304897a395435237cab 266 SUPERFAMILY SSF52540 15 259 4.06E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13120 ef20d263924fe304897a395435237cab 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS13120 ef20d263924fe304897a395435237cab 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS13120 ef20d263924fe304897a395435237cab 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS13120 ef20d263924fe304897a395435237cab 266 SUPERFAMILY SSF52540 15 259 4.06E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08340 ef20d263924fe304897a395435237cab 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS08340 ef20d263924fe304897a395435237cab 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08340 ef20d263924fe304897a395435237cab 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08340 ef20d263924fe304897a395435237cab 266 SUPERFAMILY SSF52540 15 259 4.06E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04755 ef20d263924fe304897a395435237cab 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS04755 ef20d263924fe304897a395435237cab 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04755 ef20d263924fe304897a395435237cab 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04755 ef20d263924fe304897a395435237cab 266 SUPERFAMILY SSF52540 15 259 4.06E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02875 ef20d263924fe304897a395435237cab 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS02875 ef20d263924fe304897a395435237cab 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02875 ef20d263924fe304897a395435237cab 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02875 ef20d263924fe304897a395435237cab 266 SUPERFAMILY SSF52540 15 259 4.06E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08405 5988b0476e458543449c6cead15db618 226 TIGRFAM TIGR00498 lexA: repressor LexA 3 226 6.6E-75 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 HVS_RS08405 5988b0476e458543449c6cead15db618 226 SUPERFAMILY SSF51306 104 224 8.89E-38 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS08405 5988b0476e458543449c6cead15db618 226 Hamap MF_00015 LexA repressor [lexA]. 4 226 33.37 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 HVS_RS08405 5988b0476e458543449c6cead15db618 226 Pfam PF00717 Peptidase S24-like 144 210 6.6E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS08405 5988b0476e458543449c6cead15db618 226 Gene3D G3DSA:1.10.10.10 3 69 1.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08405 5988b0476e458543449c6cead15db618 226 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 180 192 1.2E-8 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HVS_RS08405 5988b0476e458543449c6cead15db618 226 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 141 151 1.2E-8 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HVS_RS08405 5988b0476e458543449c6cead15db618 226 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 152 163 1.2E-8 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 HVS_RS08405 5988b0476e458543449c6cead15db618 226 SUPERFAMILY SSF46785 4 70 2.69E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08405 5988b0476e458543449c6cead15db618 226 Pfam PF01726 LexA DNA binding domain 3 66 6.9E-24 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 HVS_RS08405 5988b0476e458543449c6cead15db618 226 Gene3D G3DSA:2.10.109.10 110 226 2.3E-27 T 29-03-2018 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Gene3D G3DSA:3.40.50.620 1 226 5.0E-81 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Pfam PF08264 Anticodon-binding domain of tRNA 660 788 1.9E-23 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 824 23.603 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Gene3D G3DSA:3.40.50.620 406 608 9.5E-72 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 3 576 1.1E-276 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 405 1.7E-73 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 11 169 1.8E-28 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 419 620 9.8E-25 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 51 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 SUPERFAMILY SSF47323 623 825 6.92E-38 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 SUPERFAMILY SSF52374 418 628 8.97E-157 T 29-03-2018 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 SUPERFAMILY SSF52374 1 224 8.97E-157 T 29-03-2018 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 562 572 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 490 508 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 125 142 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 183 196 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 151 167 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 PRINTS PR00985 Leucyl-tRNA synthetase signature 529 551 1.1E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Gene3D G3DSA:1.10.730.10 609 761 8.1E-40 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 SUPERFAMILY SSF50677 224 417 4.08E-55 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 HVS_RS06270 33979ef9e03039d21c21d29296f74713 825 Gene3D G3DSA:3.90.740.10 227 405 7.1E-54 T 29-03-2018 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 36.784 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 Pfam PF01430 Hsp33 protein 3 280 2.1E-85 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 SUPERFAMILY SSF118352 232 289 9.16E-18 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 Gene3D G3DSA:3.90.1280.10 235 288 3.2E-19 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 Gene3D G3DSA:3.55.30.10 2 234 2.1E-72 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 SUPERFAMILY SSF64397 4 242 1.31E-71 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HVS_RS14305 5f405397f4cc9d022b688076f837fad1 292 PIRSF PIRSF005261 1 292 3.8E-76 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HVS_RS00090 26a73e7213f6f7313250a250c13142b6 596 Pfam PF07501 G5 domain 494 563 2.5E-15 T 29-03-2018 IPR011098 G5 domain HVS_RS00090 26a73e7213f6f7313250a250c13142b6 596 Pfam PF04294 VanW like protein 350 478 3.9E-51 T 29-03-2018 IPR007391 Vancomycin resistance VanW HVS_RS00090 26a73e7213f6f7313250a250c13142b6 596 Pfam PF12229 Putative peptidoglycan binding domain 127 239 2.1E-16 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain HVS_RS00090 26a73e7213f6f7313250a250c13142b6 596 Pfam PF12229 Putative peptidoglycan binding domain 253 303 8.1E-6 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain HVS_RS00090 26a73e7213f6f7313250a250c13142b6 596 SMART SM01208 487 564 8.6E-19 T 29-03-2018 IPR011098 G5 domain HVS_RS00090 26a73e7213f6f7313250a250c13142b6 596 Gene3D G3DSA:2.20.230.10 490 564 9.9E-15 T 29-03-2018 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Gene3D G3DSA:3.30.70.870 398 489 7.5E-35 T 29-03-2018 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SUPERFAMILY SSF52540 6 280 3.63E-109 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 8.8E-15 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SUPERFAMILY SSF50447 263 402 1.46E-38 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Gene3D G3DSA:2.40.30.10 288 397 1.1E-32 T 29-03-2018 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SUPERFAMILY SSF54980 400 478 8.27E-24 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SUPERFAMILY SSF54211 477 596 2.3E-46 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Gene3D G3DSA:3.30.70.240 612 689 4.2E-33 T 29-03-2018 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SMART SM00889 478 596 1.7E-77 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 5.3E-35 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Gene3D G3DSA:3.40.50.300 1 285 8.8E-62 T 29-03-2018 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Pfam PF14492 Elongation Factor G, domain II 402 475 1.7E-34 T 29-03-2018 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 6.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 6.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 6.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Pfam PF00679 Elongation factor G C-terminus 598 684 9.8E-33 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 113.493 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Pfam PF03764 Elongation factor G, domain IV 477 596 2.1E-51 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SMART SM00838 598 685 6.2E-61 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 SUPERFAMILY SSF54980 601 688 2.16E-31 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Gene3D G3DSA:3.30.230.10 490 611 1.9E-46 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS12930 d43d2676eade09f1f0f1f8f54eb45446 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 1.6E-65 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11540 bd21954d0563c88769d4818844110c50 178 Gene3D G3DSA:1.10.10.10 3 112 6.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11540 bd21954d0563c88769d4818844110c50 178 Pfam PF14277 Domain of unknown function (DUF4364) 12 173 1.2E-55 T 29-03-2018 IPR025374 Protein of unknown function DUF4364 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SMART SM00957 5 398 2.3E-301 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SMART SM00958 227 354 6.1E-67 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Gene3D G3DSA:1.10.3060.10 658 768 1.7E-31 T 29-03-2018 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Gene3D G3DSA:1.10.3060.10 769 866 2.6E-25 T 29-03-2018 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Gene3D G3DSA:3.40.50.300 413 657 7.8E-55 T 29-03-2018 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SUPERFAMILY SSF81767 230 364 2.09E-43 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SUPERFAMILY SSF52540 364 411 2.75E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SUPERFAMILY SSF52540 3 227 2.75E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Gene3D G3DSA:3.40.50.300 305 412 5.4E-9 T 29-03-2018 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Gene3D G3DSA:3.40.50.300 8 270 1.0E-60 T 29-03-2018 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SUPERFAMILY SSF52540 413 642 2.08E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Pfam PF07516 SecA Wing and Scaffold domain 641 852 1.1E-68 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Pfam PF02810 SEC-C motif 891 908 2.7E-8 T 29-03-2018 IPR004027 SEC-C motif HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 856 20.56 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Pfam PF01043 SecA preprotein cross-linking domain 231 354 1.6E-40 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 Pfam PF07517 SecA DEAD-like domain 6 398 5.4E-138 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 116 126 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 100 114 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 372 389 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 169 189 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 335 357 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 62 86 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 PRINTS PR00906 SecA protein signature 409 422 2.2E-71 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 842 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 ProSitePatterns PS01312 SecA family signature. 496 511 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 HVS_RS11305 08120570b5b978cb2fbd38e1a82a5736 910 SUPERFAMILY SSF81886 644 899 7.32E-78 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 Gene3D G3DSA:3.40.50.140 3 160 8.5E-36 T 29-03-2018 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 Gene3D G3DSA:1.10.460.10 498 636 4.9E-21 T 29-03-2018 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 Gene3D G3DSA:1.10.460.10 165 383 1.2E-41 T 29-03-2018 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 Pfam PF01751 Toprim domain 5 139 1.3E-11 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 Pfam PF01131 DNA topoisomerase 158 610 8.1E-115 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 SMART SM00493 3 132 7.1E-14 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 537 551 1.1E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 1.1E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 204 222 1.1E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 418 434 1.1E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 331 340 1.1E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 Gene3D G3DSA:2.70.20.10 384 497 2.4E-29 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 SMART SM00437 289 576 9.4E-86 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 TIGRFAM TIGR01056 topB: DNA topoisomerase III 4 634 1.2E-168 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 SUPERFAMILY SSF56712 3 628 1.2E-165 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 SMART SM00436 132 234 4.2E-25 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HVS_RS15385 7da05b53db66ed22eebba457f5ceb5c2 644 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 326 340 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 Gene3D G3DSA:3.30.450.40 69 218 1.5E-6 T 29-03-2018 IPR029016 GAF domain-like HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 236 397 1.4E-51 T 29-03-2018 IPR000160 GGDEF domain HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 SUPERFAMILY SSF55073 245 399 3.84E-49 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 SMART SM00267 229 399 1.0E-62 T 29-03-2018 IPR000160 GGDEF domain HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 Gene3D G3DSA:3.30.70.270 234 404 1.2E-56 T 29-03-2018 HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 Pfam PF00990 Diguanylate cyclase, GGDEF domain 240 394 2.0E-48 T 29-03-2018 IPR000160 GGDEF domain HVS_RS01180 605143fd3663de461c266dcd37095f6f 405 SUPERFAMILY SSF55781 75 218 2.4E-7 T 29-03-2018 IPR029016 GAF domain-like HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:3.10.20.30 8 124 4.0E-13 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:3.30.70.20 171 212 3.0E-9 T 29-03-2018 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 242 526 1.5E-97 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Pfam PF00037 4Fe-4S binding domain 206 225 7.3E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:4.10.260.20 535 593 1.5E-22 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:3.30.70.20 213 286 1.2E-5 T 29-03-2018 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 SUPERFAMILY SSF54292 12 94 7.36E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 SMART SM00929 103 143 2.5E-20 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Pfam PF02256 Iron hydrogenase small subunit 536 590 2.9E-22 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 158 530 8.0E-163 T 29-03-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:3.40.950.10 415 520 3.2E-22 T 29-03-2018 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:3.40.950.10 291 414 1.0E-29 T 29-03-2018 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 SUPERFAMILY SSF53920 209 587 9.16E-133 T 29-03-2018 IPR009016 Iron hydrogenase HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 96 4.5E-16 T 29-03-2018 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Gene3D G3DSA:3.30.70.20 125 170 0.089 T 29-03-2018 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 SMART SM00902 532 591 8.3E-24 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 209 220 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 103 142 2.5E-19 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11455 364abacd141cc51c2704b85b7c65e97b 593 SUPERFAMILY SSF54862 96 234 5.02E-37 T 29-03-2018 HVS_RS07465 2fd324ccde22691db05ab59c2cc77a7c 452 SMART SM01208 373 451 5.3E-5 T 29-03-2018 IPR011098 G5 domain HVS_RS07465 2fd324ccde22691db05ab59c2cc77a7c 452 Pfam PF04294 VanW like protein 235 363 6.9E-49 T 29-03-2018 IPR007391 Vancomycin resistance VanW HVS_RS07465 2fd324ccde22691db05ab59c2cc77a7c 452 Gene3D G3DSA:2.20.230.10 374 449 1.3E-5 T 29-03-2018 HVS_RS07465 2fd324ccde22691db05ab59c2cc77a7c 452 Pfam PF12229 Putative peptidoglycan binding domain 83 194 2.1E-16 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain HVS_RS07465 2fd324ccde22691db05ab59c2cc77a7c 452 Pfam PF07501 G5 domain 384 448 4.0E-7 T 29-03-2018 IPR011098 G5 domain HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 Gene3D G3DSA:3.40.50.2300 1 258 1.5E-35 T 29-03-2018 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 SMART SM00448 2 117 6.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 Pfam PF12833 Helix-turn-helix domain 445 521 7.4E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 SUPERFAMILY SSF52172 2 131 5.27E-34 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 SMART SM00342 437 520 7.7E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 489 504 2.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 504 520 2.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 Gene3D G3DSA:2.60.120.10 297 476 4.7E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 Pfam PF00072 Response regulator receiver domain 4 118 1.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 474 516 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 Gene3D G3DSA:1.10.10.60 477 526 7.9E-15 T 29-03-2018 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 SUPERFAMILY SSF46689 473 524 2.96E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS02280 7f5ac0db7fcfc0d9cb6836d34287b0fe 530 SUPERFAMILY SSF46689 421 471 3.49E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 SMART SM00382 192 331 1.6E-25 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 Gene3D G3DSA:3.40.50.300 146 337 1.7E-61 T 29-03-2018 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 Gene3D G3DSA:1.10.8.60 338 422 2.7E-24 T 29-03-2018 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 8 601 36.751 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 SUPERFAMILY SSF52540 150 397 1.52E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 Pfam PF01434 Peptidase family M41 389 598 6.2E-71 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 196 328 9.1E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 Pfam PF06480 FtsH Extracellular 9 77 4.4E-7 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 SUPERFAMILY SSF140990 410 600 2.75E-66 T 29-03-2018 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 ProSitePatterns PS00674 AAA-protein family signature. 299 317 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 HVS_RS01330 58723f4c6acb6a8ef2ceb72bad5222c3 603 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 109 599 3.7E-233 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 Gene3D G3DSA:1.10.10.10 129 219 1.0E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 SMART SM00448 4 117 7.7E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 Pfam PF00072 Response regulator receiver domain 6 118 1.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 SUPERFAMILY SSF46894 150 215 8.84E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 SUPERFAMILY SSF52172 3 134 3.98E-37 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 SMART SM00421 152 209 3.2E-29 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 4.4E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10740 4a81818cd12ccbc89970e224c9174eed 223 Gene3D G3DSA:3.40.50.2300 3 128 5.8E-37 T 29-03-2018 HVS_RS14475 474826548d8370a9f73164d65fe13b1a 552 Pfam PF03888 MucB/RseB N-terminal domain 131 252 1.1E-6 T 29-03-2018 IPR033434 MucB/RseB, N-terminal HVS_RS14475 474826548d8370a9f73164d65fe13b1a 552 Gene3D G3DSA:2.50.20.10 100 355 1.4E-18 T 29-03-2018 HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 2.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 Gene3D G3DSA:1.10.10.10 1 88 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 SMART SM00418 10 89 1.5E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.6E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.6E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 3.6E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02905 f72405f68575c44dddcd0d398841ae77 96 SUPERFAMILY SSF46785 5 92 3.55E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 2.4E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 Gene3D G3DSA:1.10.10.10 1 88 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 SMART SM00418 10 89 1.5E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.6E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.6E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 3.6E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03580 f72405f68575c44dddcd0d398841ae77 96 SUPERFAMILY SSF46785 5 92 3.55E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS06375 487cb160b4504111899afd976912faa0 380 Gene3D G3DSA:3.40.50.720 2 147 4.3E-47 T 29-03-2018 HVS_RS06375 487cb160b4504111899afd976912faa0 380 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 143 226 8.4E-42 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 SUPERFAMILY SSF69055 288 379 2.75E-33 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 378 9.7E-155 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 129 1.9E-39 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 SUPERFAMILY SSF55347 123 261 1.8E-62 T 29-03-2018 HVS_RS06375 487cb160b4504111899afd976912faa0 380 SUPERFAMILY SSF51735 3 147 3.94E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS06375 487cb160b4504111899afd976912faa0 380 Pfam PF13288 DXP reductoisomerase C-terminal domain 258 374 1.6E-43 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 379 47.805 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 PIRSF PIRSF006205 2 380 3.2E-163 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 HVS_RS06375 487cb160b4504111899afd976912faa0 380 Gene3D G3DSA:1.10.1740.10 300 380 1.9E-31 T 29-03-2018 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 195 43.467 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 Gene3D G3DSA:3.30.230.40 91 196 3.6E-34 T 29-03-2018 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 2.4E-66 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 SUPERFAMILY SSF54211 3 87 5.82E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 Gene3D G3DSA:3.30.230.40 3 89 4.6E-33 T 29-03-2018 HVS_RS15255 2c777d185264d2a906e1ed57d4671b63 196 SUPERFAMILY SSF54211 89 180 5.69E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 3.7E-98 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 SMART SM00853 537 679 4.0E-42 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 211 326 2.8E-40 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 Gene3D G3DSA:3.30.230.10 214 326 6.6E-34 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 120 1.1E-12 T 29-03-2018 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 SMART SM01340 209 327 7.0E-53 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 SUPERFAMILY SSF118116 534 721 1.31E-52 T 29-03-2018 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 Gene3D G3DSA:3.30.565.10 8 199 4.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 SUPERFAMILY SSF55874 3 214 1.1E-53 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 SUPERFAMILY SSF54211 191 326 3.79E-38 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 719 26.54 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 HVS_RS08420 f1e2a71b3826c84c427174d91e622dca 723 Pfam PF08676 MutL C terminal dimerisation domain 537 679 4.5E-40 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HVS_RS06310 101eeb5b5f5f40940811e63d0d34a8c2 547 Pfam PF00905 Penicillin binding protein transpeptidase domain 233 539 6.6E-55 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HVS_RS06310 101eeb5b5f5f40940811e63d0d34a8c2 547 SUPERFAMILY SSF56601 214 543 5.83E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS06310 101eeb5b5f5f40940811e63d0d34a8c2 547 SUPERFAMILY SSF56519 49 207 7.19E-18 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HVS_RS06310 101eeb5b5f5f40940811e63d0d34a8c2 547 Gene3D G3DSA:3.40.710.10 205 546 2.3E-80 T 29-03-2018 HVS_RS06310 101eeb5b5f5f40940811e63d0d34a8c2 547 Gene3D G3DSA:3.90.1310.10 18 195 1.1E-21 T 29-03-2018 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Pfam PF00759 Glycosyl hydrolase family 9 856 1292 7.1E-93 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 SUPERFAMILY SSF81296 756 851 2.1E-15 T 29-03-2018 IPR014756 Immunoglobulin E-set HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:2.60.40.10 761 853 7.7E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:2.60.120.260 300 440 7.7E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:2.60.120.260 112 276 3.4E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 1209 1225 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 SUPERFAMILY SSF49785 445 589 1.67E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 SUPERFAMILY SSF48208 853 1297 1.18E-106 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Pfam PF02018 Carbohydrate binding domain 446 556 3.3E-9 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Pfam PF02018 Carbohydrate binding domain 602 728 5.4E-22 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Pfam PF02018 Carbohydrate binding domain 296 416 4.1E-8 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:2.60.120.260 596 759 6.6E-28 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:2.60.120.260 445 595 4.4E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Pfam PF02927 Cellulase N-terminal ig-like domain 759 844 5.0E-15 T 29-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:1.50.10.10 854 1300 6.1E-103 T 29-03-2018 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 Gene3D G3DSA:1.10.1330.10 39 111 0.0017 T 29-03-2018 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 SUPERFAMILY SSF49785 599 747 9.86E-35 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 SUPERFAMILY SSF63446 40 112 1.83E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07815 5aebe255cc418920aeb1f61e4311fedb 1303 SUPERFAMILY SSF49785 293 437 2.41E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS06850 547418118cb0daf2240479886bf570ad 71 Gene3D G3DSA:1.10.8.60 9 71 3.8E-4 T 29-03-2018 HVS_RS06065 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 Pfam PF01726 LexA DNA binding domain 11 71 3.0E-17 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 HVS_RS06065 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 Gene3D G3DSA:1.10.10.10 10 75 2.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS06065 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 SUPERFAMILY SSF51306 86 209 1.08E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS06065 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 TIGRFAM TIGR00498 lexA: repressor LexA 11 211 5.2E-34 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 HVS_RS06065 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 Gene3D G3DSA:2.10.109.10 94 214 1.8E-10 T 29-03-2018 HVS_RS06065 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 SUPERFAMILY SSF46785 11 76 1.23E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14760 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 Pfam PF01726 LexA DNA binding domain 11 71 3.0E-17 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 HVS_RS14760 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 Gene3D G3DSA:1.10.10.10 10 75 2.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14760 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 SUPERFAMILY SSF51306 86 209 1.08E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS14760 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 TIGRFAM TIGR00498 lexA: repressor LexA 11 211 5.2E-34 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 HVS_RS14760 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 Gene3D G3DSA:2.10.109.10 94 214 1.8E-10 T 29-03-2018 HVS_RS14760 ad8a0fe3f87e248f37d1a1e5b0bbddbc 214 SUPERFAMILY SSF46785 11 76 1.23E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10265 60c020b103501bd0fb1d672ab813556f 99 Pfam PF02049 Flagellar hook-basal body complex protein FliE 21 99 5.2E-29 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HVS_RS10265 60c020b103501bd0fb1d672ab813556f 99 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 15 99 2.4E-20 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HVS_RS10265 60c020b103501bd0fb1d672ab813556f 99 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 99 18.014 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HVS_RS10265 60c020b103501bd0fb1d672ab813556f 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 63 79 5.2E-12 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HVS_RS10265 60c020b103501bd0fb1d672ab813556f 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 84 97 5.2E-12 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HVS_RS10265 60c020b103501bd0fb1d672ab813556f 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 29 45 5.2E-12 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 HVS_RS00350 7d824e8efdf1484c82bbe781c6ae23c7 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 11 74 5.6E-11 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HVS_RS06370 d62ae9b8caea4e90f2d7be4dfc63f27c 274 Pfam PF01148 Cytidylyltransferase family 2 270 3.2E-60 T 29-03-2018 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 SUPERFAMILY SSF52540 202 375 2.07E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 SUPERFAMILY SSF52540 78 168 2.07E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 224 244 3.4E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 291 309 3.4E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 125 3.6E-42 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Gene3D G3DSA:3.30.1360.120 1 125 1.6E-46 T 29-03-2018 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Gene3D G3DSA:1.20.120.430 126 286 1.1E-30 T 29-03-2018 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 459 34.925 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 459 1.3E-133 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 SUPERFAMILY SSF116878 126 225 1.83E-50 T 29-03-2018 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 SUPERFAMILY SSF116878 384 459 1.83E-50 T 29-03-2018 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Pfam PF01926 50S ribosome-binding GTPase 224 336 3.2E-28 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 376 6.5E-29 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Gene3D G3DSA:1.20.120.430 287 459 5.6E-33 T 29-03-2018 HVS_RS16180 205b447cd828c77fec894683a3b783ee 459 Pfam PF12631 MnmE helical domain 128 456 2.8E-59 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 HVS_RS06220 52ba98cadf70438f8176a89da21105c3 166 SMART SM01001 7 152 1.6E-12 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS06220 52ba98cadf70438f8176a89da21105c3 166 SUPERFAMILY SSF52255 13 161 2.35E-29 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS06220 52ba98cadf70438f8176a89da21105c3 166 Gene3D G3DSA:3.40.50.7700 1 161 1.5E-31 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS06220 52ba98cadf70438f8176a89da21105c3 166 Pfam PF00731 AIR carboxylase 13 150 2.7E-29 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 208 4.1E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 SUPERFAMILY SSF88659 123 211 1.44E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 SUPERFAMILY SSF88946 17 105 7.59E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 Gene3D G3DSA:1.10.10.10 120 214 2.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 Pfam PF04542 Sigma-70 region 2 36 105 4.0E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 Gene3D G3DSA:1.10.1740.10 12 118 5.9E-21 T 29-03-2018 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 PIRSF PIRSF002939 1 214 7.7E-108 T 29-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 1.7E-112 T 29-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 Pfam PF08281 Sigma-70, region 4 171 205 2.1E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15700 1a0944678762bad3dde2ef6f44ed6f2f 214 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 Gene3D G3DSA:2.160.10.10 256 373 7.8E-11 T 29-03-2018 HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 SUPERFAMILY SSF53448 322 338 1.41E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 SUPERFAMILY SSF53448 2 261 1.41E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 97 105 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 Gene3D G3DSA:3.90.550.10 2 255 2.4E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 SUPERFAMILY SSF51161 232 371 6.06E-14 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 Pfam PF00483 Nucleotidyl transferase 6 257 2.6E-37 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS05465 0e75287e1347848d2fb58d3d94f9e987 373 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 3 372 2.3E-117 T 29-03-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 HVS_RS13220 45dda63568b93a7acf1655cc1e51213d 155 SUPERFAMILY SSF110857 8 130 1.7E-22 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like HVS_RS13220 45dda63568b93a7acf1655cc1e51213d 155 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 11 110 6.4E-14 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like HVS_RS13220 45dda63568b93a7acf1655cc1e51213d 155 Gene3D G3DSA:3.10.490.10 1 153 8.9E-34 T 29-03-2018 HVS_RS16080 0e5a065d1e8de96af4ba55a67c6cb0e7 325 Gene3D G3DSA:1.10.10.60 265 317 1.1E-5 T 29-03-2018 HVS_RS16080 0e5a065d1e8de96af4ba55a67c6cb0e7 325 Pfam PF04754 Putative transposase, YhgA-like 9 211 1.7E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS16080 0e5a065d1e8de96af4ba55a67c6cb0e7 325 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 316 1.5E-17 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA HVS_RS01250 fbd8de5de09f54ccdd66ebb37f2447ad 220 Gene3D G3DSA:1.20.5.340 3 197 0.0027 T 29-03-2018 HVS_RS01250 fbd8de5de09f54ccdd66ebb37f2447ad 220 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 211 3.0E-54 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01250 fbd8de5de09f54ccdd66ebb37f2447ad 220 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 212 22.122 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01250 fbd8de5de09f54ccdd66ebb37f2447ad 220 Pfam PF01813 ATP synthase subunit D 13 206 8.2E-60 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS09695 7bca39a9d188b42b9848ad5b73b60528 117 SMART SM00448 2 114 2.0E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09695 7bca39a9d188b42b9848ad5b73b60528 117 Pfam PF00072 Response regulator receiver domain 4 115 9.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS09695 7bca39a9d188b42b9848ad5b73b60528 117 SUPERFAMILY SSF52172 1 117 2.7E-34 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS09695 7bca39a9d188b42b9848ad5b73b60528 117 Gene3D G3DSA:3.40.50.2300 1 117 7.1E-35 T 29-03-2018 HVS_RS06295 1d160eaf810b65dd51b6acebc4853a2a 413 SUPERFAMILY SSF49384 39 148 1.13E-17 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS06295 1d160eaf810b65dd51b6acebc4853a2a 413 Pfam PF00395 S-layer homology domain 361 404 1.5E-14 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06295 1d160eaf810b65dd51b6acebc4853a2a 413 Pfam PF00395 S-layer homology domain 240 279 3.8E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06295 1d160eaf810b65dd51b6acebc4853a2a 413 Pfam PF00395 S-layer homology domain 299 342 1.0E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06295 1d160eaf810b65dd51b6acebc4853a2a 413 Gene3D G3DSA:2.60.40.680 18 178 2.2E-20 T 29-03-2018 HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 SUPERFAMILY SSF56747 5 191 1.31E-27 T 29-03-2018 HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 Gene3D G3DSA:3.40.50.300 399 618 1.7E-16 T 29-03-2018 HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 SUPERFAMILY SSF52540 450 613 3.03E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 382 682 1.9E-100 T 29-03-2018 IPR006500 DNA primase, phage/plasmid HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 9 183 1.2E-44 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 Pfam PF08708 Primase C terminal 1 (PriCT-1) 205 267 1.0E-17 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 Pfam PF08706 D5 N terminal like 282 432 1.1E-35 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 SMART SM00942 201 267 9.5E-23 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 SMART SM00885 282 433 2.0E-53 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 Pfam PF03288 Poxvirus D5 protein-like 639 690 2.1E-4 T 29-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal HVS_RS03770 49236338b38bc5637a02be0407f55e25 719 SMART SM00943 9 184 1.0E-65 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS02230 c0c440b03c61f016ebf0f9393e54bc7b 331 Gene3D G3DSA:3.60.15.10 48 312 4.7E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02230 c0c440b03c61f016ebf0f9393e54bc7b 331 Pfam PF00753 Metallo-beta-lactamase superfamily 84 280 3.3E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02230 c0c440b03c61f016ebf0f9393e54bc7b 331 SUPERFAMILY SSF56281 75 323 1.02E-62 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02230 c0c440b03c61f016ebf0f9393e54bc7b 331 SMART SM00849 86 281 1.0E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11870 9e5da342456dd689cafa2b6a5c064945 308 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 230 5.0E-37 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HVS_RS11870 9e5da342456dd689cafa2b6a5c064945 308 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 77 229 1.7E-38 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HVS_RS08160 cdbef59263730c0a245b459bb00c8aa4 294 SUPERFAMILY SSF52768 14 286 7.02E-82 T 29-03-2018 HVS_RS08160 cdbef59263730c0a245b459bb00c8aa4 294 TIGRFAM TIGR01230 agmatinase: agmatinase 14 287 4.9E-95 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 HVS_RS08160 cdbef59263730c0a245b459bb00c8aa4 294 Pfam PF00491 Arginase family 25 285 1.9E-79 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 HVS_RS08160 cdbef59263730c0a245b459bb00c8aa4 294 PIRSF PIRSF036979 4 292 8.2E-94 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 HVS_RS08160 cdbef59263730c0a245b459bb00c8aa4 294 Gene3D G3DSA:3.40.800.10 17 294 1.7E-77 T 29-03-2018 HVS_RS02865 4a6b26ea8cd2436658cbe0cdd609249e 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 92 117 9.8E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HVS_RS02865 4a6b26ea8cd2436658cbe0cdd609249e 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 129 153 9.8E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HVS_RS02865 4a6b26ea8cd2436658cbe0cdd609249e 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 166 185 9.8E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HVS_RS02865 4a6b26ea8cd2436658cbe0cdd609249e 244 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 9.8E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HVS_RS02865 4a6b26ea8cd2436658cbe0cdd609249e 244 PIRSF PIRSF006648 1 242 1.4E-20 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HVS_RS02865 4a6b26ea8cd2436658cbe0cdd609249e 244 Pfam PF01061 ABC-2 type transporter 7 204 2.7E-29 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 HVS_RS04940 088652e1da18e5f5e491adb18ccc52ab 158 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 90 1.1E-9 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HVS_RS02895 088652e1da18e5f5e491adb18ccc52ab 158 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 90 1.1E-9 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HVS_RS02065 088652e1da18e5f5e491adb18ccc52ab 158 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 90 1.1E-9 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HVS_RS04030 a5930fd4bd3b3f04abb472d40ff142cf 184 Gene3D G3DSA:2.170.16.10 3 17 0.16 T 29-03-2018 HVS_RS04030 a5930fd4bd3b3f04abb472d40ff142cf 184 Pfam PF07591 Pretoxin HINT domain 21 94 5.8E-18 T 29-03-2018 HVS_RS04030 a5930fd4bd3b3f04abb472d40ff142cf 184 Gene3D G3DSA:2.170.16.10 18 95 3.6E-19 T 29-03-2018 HVS_RS04030 a5930fd4bd3b3f04abb472d40ff142cf 184 Pfam PF15529 Bacterial toxin 24 93 183 3.6E-19 T 29-03-2018 IPR029114 Bacterial toxin 24 HVS_RS04030 a5930fd4bd3b3f04abb472d40ff142cf 184 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 70 94 2.0E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS04030 a5930fd4bd3b3f04abb472d40ff142cf 184 SUPERFAMILY SSF51294 13 94 8.95E-18 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS00150 27c081d595ef5f9ad2b5bb65f672b6f8 328 SUPERFAMILY SSF56112 25 324 2.04E-44 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS00150 27c081d595ef5f9ad2b5bb65f672b6f8 328 Gene3D G3DSA:3.90.1200.10 92 325 3.7E-40 T 29-03-2018 HVS_RS00150 27c081d595ef5f9ad2b5bb65f672b6f8 328 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 15 324 5.1E-103 T 29-03-2018 IPR014255 Spore coat protein CotS HVS_RS00150 27c081d595ef5f9ad2b5bb65f672b6f8 328 Pfam PF01633 Choline/ethanolamine kinase 186 240 1.5E-10 T 29-03-2018 HVS_RS00150 27c081d595ef5f9ad2b5bb65f672b6f8 328 Gene3D G3DSA:3.30.200.20 1 91 4.9E-6 T 29-03-2018 HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 SUPERFAMILY SSF53383 2 423 3.24E-128 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 2 425 99.94 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 423 1.6E-187 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 Pfam PF00202 Aminotransferase class-III 32 414 2.0E-77 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 Gene3D G3DSA:3.90.1150.10 312 427 2.8E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 Gene3D G3DSA:3.90.1150.10 1 174 6.7E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS02625 d69e0e15bcb429869f7da7f6eb2ec5c5 430 Gene3D G3DSA:3.40.640.10 175 311 1.6E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 PIRSF PIRSF000159 1 1184 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Gene3D G3DSA:3.40.50.920 259 416 3.9E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 427 612 9.2E-35 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 SUPERFAMILY SSF54862 678 836 1.95E-19 T 29-03-2018 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 SUPERFAMILY SSF52922 260 406 8.14E-48 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 SUPERFAMILY SSF52518 797 1179 1.53E-111 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 SMART SM00890 625 687 1.4E-12 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Gene3D G3DSA:3.40.50.970 791 1180 1.3E-106 T 29-03-2018 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 752 763 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 6 1177 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 SUPERFAMILY SSF53323 417 667 1.31E-80 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Pfam PF12838 4Fe-4S dicluster domain 696 766 1.0E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Gene3D G3DSA:3.30.70.20 677 788 2.1E-24 T 29-03-2018 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Gene3D G3DSA:4.10.780.10 640 676 1.5E-11 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Pfam PF10371 Domain of unknown function 634 686 4.6E-16 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 SUPERFAMILY SSF52518 4 258 1.41E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 964 1076 6.5E-10 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 369 8.9E-15 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 247 7.0E-78 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Gene3D G3DSA:3.40.50.970 2 258 7.0E-53 T 29-03-2018 HVS_RS10780 60a89d9492ffe432fafd39abd5501f0e 1184 Gene3D G3DSA:3.40.920.10 417 628 1.9E-64 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 SMART SM00487 252 463 1.6E-8 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 15 220 1.1E-20 T 29-03-2018 IPR006483 CRISPR-associated Cas3-HD domain HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 Gene3D G3DSA:1.10.3210.10 31 261 0.0017 T 29-03-2018 HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 SMART SM00490 494 575 1.0E-8 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 270 611 2.5E-74 T 29-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 Gene3D G3DSA:3.40.50.300 262 431 1.4E-15 T 29-03-2018 HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 Gene3D G3DSA:3.40.50.300 448 615 1.9E-16 T 29-03-2018 HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 Pfam PF00271 Helicase conserved C-terminal domain 471 575 1.1E-9 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 Pfam PF00270 DEAD/DEAH box helicase 265 434 2.2E-9 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS04970 7bb8bddb8b67c6d640c1d4fb4d044ead 755 SUPERFAMILY SSF52540 266 588 1.24E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 SUPERFAMILY SSF51366 1 288 7.85E-82 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 Gene3D G3DSA:3.20.20.70 1 305 1.4E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 SMART SM00934 16 285 1.7E-29 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 1 307 36.554 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 2 281 9.2E-87 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 101 114 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08900 fee5b100ea236e0d459943b2bc7f5edc 310 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 57 279 3.9E-25 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS16075 541b05b14c95356f45ea77ff35d6dc12 302 SUPERFAMILY SSF55383 26 109 4.58E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16075 541b05b14c95356f45ea77ff35d6dc12 302 Pfam PF07833 Copper amine oxidase N-terminal domain 23 115 8.2E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16075 541b05b14c95356f45ea77ff35d6dc12 302 Gene3D G3DSA:3.30.457.10 36 97 5.8E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16075 541b05b14c95356f45ea77ff35d6dc12 302 Gene3D G3DSA:3.30.457.10 4 35 2.1E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16075 541b05b14c95356f45ea77ff35d6dc12 302 Gene3D G3DSA:3.30.457.10 98 188 1.8E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 15 464 31.682 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 Gene3D G3DSA:3.40.1190.10 113 321 3.9E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 SUPERFAMILY SSF53244 317 463 1.34E-36 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 SUPERFAMILY SSF51984 15 105 8.89E-13 T 29-03-2018 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 16 462 5.5E-115 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 SUPERFAMILY SSF53623 109 315 1.7E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 Gene3D G3DSA:3.90.190.20 322 463 3.4E-33 T 29-03-2018 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 Pfam PF08245 Mur ligase middle domain 122 299 2.4E-39 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS07545 de45062aa83bf0a5eb96a2fd71dbf85d 467 Gene3D G3DSA:3.40.50.720 1 106 9.0E-10 T 29-03-2018 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 33 50 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Pfam PF02256 Iron hydrogenase small subunit 522 576 3.1E-25 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 SUPERFAMILY SSF53920 191 573 6.8E-140 T 29-03-2018 IPR009016 Iron hydrogenase HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 225 508 1.0E-102 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 SUPERFAMILY SSF54292 3 76 2.42E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 SMART SM00929 85 125 2.9E-18 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 140 512 3.6E-174 T 29-03-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Pfam PF12838 4Fe-4S dicluster domain 147 205 8.6E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Gene3D G3DSA:3.30.70.20 158 191 1.1E-9 T 29-03-2018 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Gene3D G3DSA:3.40.50.1780 192 306 7.6E-33 T 29-03-2018 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Gene3D G3DSA:3.40.50.1780 307 431 1.4E-44 T 29-03-2018 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Gene3D G3DSA:3.10.20.30 1 157 2.1E-18 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Gene3D G3DSA:4.10.260.20 520 580 2.3E-25 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 78 2.2E-18 T 29-03-2018 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 85 124 3.2E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 SMART SM00902 518 577 1.3E-27 T 29-03-2018 IPR003149 Iron hydrogenase, small subunit HVS_RS12375 68ab6703cdd023bc338cd07c71918d80 583 SUPERFAMILY SSF54862 77 216 1.09E-37 T 29-03-2018 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Gene3D G3DSA:3.30.70.1110 175 254 2.9E-24 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Gene3D G3DSA:2.30.30.40 631 684 3.6E-21 T 29-03-2018 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Gene3D G3DSA:2.40.50.180 576 630 6.3E-12 T 29-03-2018 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 552 1.6E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SMART SM00260 545 684 6.5E-43 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Pfam PF01627 Hpt domain 5 98 1.9E-21 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SMART SM00387 410 553 3.5E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 469 3.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 3.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 550 3.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 531 3.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Gene3D G3DSA:1.20.120.160 1 145 1.6E-37 T 29-03-2018 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SUPERFAMILY SSF55874 367 551 3.27E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Gene3D G3DSA:3.30.565.10 367 554 6.7E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 306 365 5.0E-14 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SUPERFAMILY SSF55052 173 256 2.01E-24 T 29-03-2018 IPR015162 CheY binding HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SMART SM00073 3 100 4.1E-33 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SUPERFAMILY SSF47384 306 366 2.16E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Pfam PF07194 P2 response regulator binding domain 176 255 6.8E-26 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SUPERFAMILY SSF47226 2 126 1.16E-35 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SMART SM01231 305 365 2.0E-16 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Pfam PF01584 CheW-like domain 557 683 4.6E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 Gene3D G3DSA:1.10.287.560 305 366 1.9E-18 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HVS_RS10135 6c12e8f5154d9c5e347314501ba1957d 685 SUPERFAMILY SSF50341 552 683 1.09E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 293 3.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 265 279 3.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 315 3.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 334 3.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 SUPERFAMILY SSF55874 174 333 6.42E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 Pfam PF00512 His Kinase A (phospho-acceptor) domain 120 183 9.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 SMART SM00388 117 183 5.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 SMART SM00387 228 337 5.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 Gene3D G3DSA:3.30.565.10 178 335 3.6E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 SUPERFAMILY SSF47384 101 183 7.26E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 333 7.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10805 15f419a4d6c3a63d5d1b6184b94185f2 338 Gene3D G3DSA:1.10.287.130 100 177 2.5E-9 T 29-03-2018 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 SUPERFAMILY SSF52540 5 210 1.08E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Gene3D G3DSA:3.30.70.870 294 373 4.5E-29 T 29-03-2018 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Hamap MF_00071 Elongation factor 4 [lepA]. 1 603 308.393 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 SUPERFAMILY SSF54980 405 500 2.01E-24 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Gene3D G3DSA:3.30.70.240 398 555 6.2E-28 T 29-03-2018 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 181 1.2E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 SUPERFAMILY SSF54980 298 376 1.4E-19 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Pfam PF06421 GTP-binding protein LepA C-terminus 494 600 1.2E-53 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Pfam PF03144 Elongation factor Tu domain 2 210 281 3.9E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Gene3D G3DSA:2.40.30.10 193 293 2.1E-27 T 29-03-2018 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Gene3D G3DSA:3.40.50.300 4 190 8.6E-36 T 29-03-2018 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 SUPERFAMILY SSF50447 170 294 4.52E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 TIGRFAM TIGR01393 lepA: elongation factor 4 8 602 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.2E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.2E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.2E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.2E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.2E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Pfam PF00009 Elongation factor Tu GTP binding domain 8 187 3.1E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11125 e348cc59cd59f380a62bc89ed491fb8e 603 Pfam PF00679 Elongation factor G C-terminus 406 492 2.9E-23 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 Gene3D G3DSA:3.40.50.300 320 568 2.6E-13 T 29-03-2018 HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 Pfam PF00069 Protein kinase domain 11 251 2.5E-49 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 Pfam PF13614 AAA domain 318 472 2.4E-8 T 29-03-2018 IPR025669 AAA domain HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 SMART SM00220 11 255 6.0E-59 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 Gene3D G3DSA:1.10.510.10 103 319 1.2E-42 T 29-03-2018 HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 SUPERFAMILY SSF52540 318 558 2.63E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 SUPERFAMILY SSF56112 8 253 1.78E-71 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 Gene3D G3DSA:3.30.200.20 2 102 6.7E-23 T 29-03-2018 HVS_RS05855 002c3dbe92d214c2fc1751f697420b23 577 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 218 224 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 309 1.5E-84 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 313 41.783 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 SUPERFAMILY SSF53335 4 112 2.84E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 SUPERFAMILY SSF53335 141 310 2.84E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 313 5.1E-72 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 Gene3D G3DSA:3.40.50.150 82 312 7.7E-46 T 29-03-2018 HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 Pfam PF13847 Methyltransferase domain 139 224 1.6E-15 T 29-03-2018 IPR025714 Methyltransferase domain HVS_RS01675 09f2fe65f01fa8d31e17fbea55721878 315 Gene3D G3DSA:1.10.8.10 1 81 1.1E-20 T 29-03-2018 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 SUPERFAMILY SSF53223 1 120 2.21E-41 T 29-03-2018 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 279 4.6E-75 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 5.7E-87 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 SUPERFAMILY SSF51735 122 280 1.3E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.7 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 Gene3D G3DSA:3.40.50.10860 11 139 3.1E-50 T 29-03-2018 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.4E-43 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 Gene3D G3DSA:3.40.50.720 140 263 2.0E-40 T 29-03-2018 HVS_RS07275 2e2a85f43a605bbdad7d4bc3d11ca4d8 285 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 HVS_RS00070 78901c190f35579b685af4a5c2aa9e4f 163 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 34 56 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HVS_RS00070 78901c190f35579b685af4a5c2aa9e4f 163 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 159 2.6E-34 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 HVS_RS00070 78901c190f35579b685af4a5c2aa9e4f 163 Pfam PF01066 CDP-alcohol phosphatidyltransferase 10 56 6.7E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HVS_RS14950 dc4512cc183ffa04a35bd397fe35b23d 139 Gene3D G3DSA:3.40.50.300 2 134 9.3E-7 T 29-03-2018 HVS_RS14950 dc4512cc183ffa04a35bd397fe35b23d 139 SUPERFAMILY SSF52540 3 102 1.69E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:1.25.40.10 239 293 1.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SUPERFAMILY SSF52096 370 620 5.96E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:1.10.287.1110 227 238 2.5E-4 T 29-03-2018 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:1.25.40.10 128 167 4.5E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Pfam PF13181 Tetratricopeptide repeat 143 175 0.047 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Pfam PF13181 Tetratricopeptide repeat 211 240 3.0E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:1.25.40.10 57 127 6.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:1.25.40.10 294 363 1.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Pfam PF07719 Tetratricopeptide repeat 109 141 1.7E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SUPERFAMILY SSF48452 86 352 2.84E-33 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00245 425 611 2.4E-19 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:3.90.226.10 427 625 5.8E-41 T 29-03-2018 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Pfam PF00515 Tetratricopeptide repeat 283 315 2.0E-7 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 282 315 5.3E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 248 281 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 108 141 1.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 316 349 98.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 142 175 0.34 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 176 209 37.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 SMART SM00028 210 243 4.7E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Gene3D G3DSA:1.25.40.10 168 226 3.1E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13045 120c80ff2693e74f718596081da23061 625 Pfam PF03572 Peptidase family S41 451 608 1.1E-29 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS04960 08a63f3d9b96c22b7a9abbc5cdbac060 330 Pfam PF01867 CRISPR associated protein Cas1 6 285 2.6E-91 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HVS_RS04960 08a63f3d9b96c22b7a9abbc5cdbac060 330 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 325 8.7E-102 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HVS_RS04960 08a63f3d9b96c22b7a9abbc5cdbac060 330 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 330 2.4E-137 T 29-03-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 HVS_RS04960 08a63f3d9b96c22b7a9abbc5cdbac060 330 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 315 25.908 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 92 134 2.2E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 6.5E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 SMART SM01086 717 806 4.8E-37 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 SUPERFAMILY SSF81923 4 144 1.57E-31 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 717 797 9.7E-27 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Pfam PF02151 UvrB/uvrC motif 419 453 3.6E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Gene3D G3DSA:3.40.50.300 494 716 4.1E-59 T 29-03-2018 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Gene3D G3DSA:1.10.1780.10 1 78 6.4E-21 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 319 2.0E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 SMART SM00382 202 346 3.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 SMART SM00382 539 679 2.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 SUPERFAMILY SSF52540 163 476 1.03E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Gene3D G3DSA:3.40.50.300 195 344 9.5E-21 T 29-03-2018 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 573 591 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Gene3D G3DSA:1.10.8.60 347 489 8.4E-44 T 29-03-2018 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Gene3D G3DSA:1.10.1780.10 79 194 1.6E-27 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 SUPERFAMILY SSF52540 488 802 1.78E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Gene3D G3DSA:1.10.8.60 717 812 1.0E-25 T 29-03-2018 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 Pfam PF07724 AAA domain (Cdc48 subfamily) 538 711 4.9E-59 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 617 635 1.4E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 543 561 1.4E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 664 1.4E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS12630 e2039c916ccd3cdc3817237382861314 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 588 606 1.4E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS09130 c47ebd33d2e43eb6d7fff9784f65bda6 294 Pfam PF01882 Protein of unknown function DUF58 48 119 1.4E-14 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS09130 c47ebd33d2e43eb6d7fff9784f65bda6 294 SUPERFAMILY SSF53300 83 223 2.54E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09130 c47ebd33d2e43eb6d7fff9784f65bda6 294 Gene3D G3DSA:3.40.50.410 59 261 3.8E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 102 9.9E-47 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 SMART SM01403 8 102 1.1E-59 T 29-03-2018 IPR027486 Ribosomal protein S10 domain HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 4 103 28.451 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 PRINTS PR00971 Ribosomal protein S10 family signature 41 56 5.9E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 PRINTS PR00971 Ribosomal protein S10 family signature 6 19 5.9E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 PRINTS PR00971 Ribosomal protein S10 family signature 62 76 5.9E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 Pfam PF00338 Ribosomal protein S10p/S20e 8 102 1.3E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 30 45 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 SUPERFAMILY SSF54999 6 103 6.93E-39 T 29-03-2018 IPR027486 Ribosomal protein S10 domain HVS_RS15145 4dd50440fc492173473fafebbb68867f 103 Gene3D G3DSA:3.30.70.600 4 103 1.7E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 40 216 8.5E-46 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 SUPERFAMILY SSF51306 55 222 2.09E-43 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 176 195 7.3E-16 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 57 73 7.3E-16 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 142 7.3E-16 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 Gene3D G3DSA:2.10.109.10 53 226 1.1E-41 T 29-03-2018 HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 Pfam PF00717 Peptidase S24-like 64 153 2.2E-12 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS09230 62ee6389c2be58fd8af72d052a12a7c2 227 ProSitePatterns PS00760 Signal peptidases I lysine active site. 132 144 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 342 427 1.8E-21 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 Pfam PF13353 4Fe-4S single cluster domain 95 218 9.0E-13 T 29-03-2018 HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 Gene3D G3DSA:3.20.20.70 84 405 1.6E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 98 109 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 Pfam PF13186 Iron-sulfur cluster-binding domain 342 403 9.1E-7 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 SUPERFAMILY SSF102114 93 412 1.57E-57 T 29-03-2018 HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 Pfam PF04055 Radical SAM superfamily 99 245 1.3E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS09340 ad28d1d5995fdb8953d03a6027b90ea0 452 TIGRFAM TIGR03974 rSAM_six_Cys: SCIFF radical SAM maturase 2 446 6.3E-212 T 29-03-2018 IPR024025 SCIFF radical SAM maturase HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Pfam PF00679 Elongation factor G C-terminus 398 481 1.6E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 PRINTS PR00315 GTP-binding elongation factor signature 53 61 2.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 PRINTS PR00315 GTP-binding elongation factor signature 73 83 2.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 PRINTS PR00315 GTP-binding elongation factor signature 89 100 2.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 PRINTS PR00315 GTP-binding elongation factor signature 125 134 2.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Pfam PF03144 Elongation factor Tu domain 2 221 291 6.5E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Gene3D G3DSA:2.40.50.250 484 574 1.5E-36 T 29-03-2018 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Gene3D G3DSA:2.40.30.10 187 301 6.5E-22 T 29-03-2018 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 SUPERFAMILY SSF54980 304 389 1.15E-16 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 141 2.6E-21 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 SUPERFAMILY SSF54980 400 514 8.63E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 598 3.9E-291 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Gene3D G3DSA:3.40.50.300 70 186 8.9E-32 T 29-03-2018 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 1.2E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 SUPERFAMILY SSF52540 4 208 2.57E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Gene3D G3DSA:3.40.50.300 2 69 2.7E-10 T 29-03-2018 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Gene3D G3DSA:3.30.70.240 403 483 1.2E-16 T 29-03-2018 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 SUPERFAMILY SSF50447 154 300 6.63E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 Gene3D G3DSA:3.30.70.870 304 402 6.2E-35 T 29-03-2018 HVS_RS06330 2e32dece1b5c5fd463001a6d2d8f016e 599 SMART SM00838 397 485 0.0033 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 SUPERFAMILY SSF82866 98 313 5.23E-35 T 29-03-2018 HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 109 301 2.7E-44 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 PRINTS PR01755 Bacterial translocase SecF protein signature 248 263 1.6E-20 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 PRINTS PR01755 Bacterial translocase SecF protein signature 216 234 1.6E-20 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 PRINTS PR01755 Bacterial translocase SecF protein signature 164 178 1.6E-20 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 PRINTS PR01755 Bacterial translocase SecF protein signature 30 45 1.6E-20 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 2 315 26.187 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 Pfam PF02355 Protein export membrane protein 129 312 3.8E-56 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 32 304 9.4E-60 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 HVS_RS09325 15f6e26e44adffd97aabaa334f8dd3a8 324 Gene3D G3DSA:1.20.1640.10 107 324 1.0E-30 T 29-03-2018 HVS_RS05520 d868de89c637815ad6c00c3b076918d7 412 SUPERFAMILY SSF52540 60 352 4.88E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05520 d868de89c637815ad6c00c3b076918d7 412 Pfam PF00437 Type II/IV secretion system protein 70 345 9.5E-80 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS05520 d868de89c637815ad6c00c3b076918d7 412 Gene3D G3DSA:3.30.450.90 51 166 1.0E-36 T 29-03-2018 HVS_RS05520 d868de89c637815ad6c00c3b076918d7 412 Gene3D G3DSA:3.40.50.300 167 409 4.3E-20 T 29-03-2018 HVS_RS15060 8b8a8b1c4d9cbcf808eb8fb2836c52c7 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 7 122 1.1E-45 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15060 8b8a8b1c4d9cbcf808eb8fb2836c52c7 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 122 28.707 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15060 8b8a8b1c4d9cbcf808eb8fb2836c52c7 122 Gene3D G3DSA:3.30.420.100 1 122 6.5E-43 T 29-03-2018 HVS_RS15060 8b8a8b1c4d9cbcf808eb8fb2836c52c7 122 SUPERFAMILY SSF53137 7 120 3.49E-53 T 29-03-2018 HVS_RS15060 8b8a8b1c4d9cbcf808eb8fb2836c52c7 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 122 3.5E-41 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01660 aebdfa7f14c634391980a752a862f874 191 Pfam PF04205 FMN-binding domain 91 178 9.5E-19 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 HVS_RS01660 aebdfa7f14c634391980a752a862f874 191 PIRSF PIRSF006091 1 184 1.1E-35 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HVS_RS01660 aebdfa7f14c634391980a752a862f874 191 SMART SM00900 91 181 2.8E-20 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 HVS_RS01660 aebdfa7f14c634391980a752a862f874 191 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 8 179 4.1E-34 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HVS_RS01660 aebdfa7f14c634391980a752a862f874 191 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 1 183 21.136 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 HVS_RS03175 7ace3ce1bf3c7881bc7bb5fde1f9976b 151 Gene3D G3DSA:3.40.630.30 1 151 2.8E-35 T 29-03-2018 HVS_RS03175 7ace3ce1bf3c7881bc7bb5fde1f9976b 151 SUPERFAMILY SSF55729 7 148 1.42E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS03175 7ace3ce1bf3c7881bc7bb5fde1f9976b 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 15 146 1.1E-44 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 HVS_RS03175 7ace3ce1bf3c7881bc7bb5fde1f9976b 151 Pfam PF00583 Acetyltransferase (GNAT) family 19 126 9.0E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS15730 1962b6d36d4acaad7c2112a428dadec2 121 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 16 115 1.5E-16 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV HVS_RS14625 69076ba35fdee191982021aee4477958 56 PRINTS PR00354 7Fe ferredoxin signature 17 27 2.4E-6 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 HVS_RS14625 69076ba35fdee191982021aee4477958 56 PRINTS PR00354 7Fe ferredoxin signature 33 50 2.4E-6 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 HVS_RS14625 69076ba35fdee191982021aee4477958 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS14625 69076ba35fdee191982021aee4477958 56 Pfam PF00037 4Fe-4S binding domain 31 53 2.7E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS14625 69076ba35fdee191982021aee4477958 56 Pfam PF00037 4Fe-4S binding domain 3 25 5.9E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS14625 69076ba35fdee191982021aee4477958 56 Gene3D G3DSA:3.30.70.20 2 56 5.5E-17 T 29-03-2018 HVS_RS14625 69076ba35fdee191982021aee4477958 56 SUPERFAMILY SSF54862 1 53 6.12E-19 T 29-03-2018 HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 Gene3D G3DSA:3.30.70.260 298 356 7.0E-10 T 29-03-2018 HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 SUPERFAMILY SSF51735 5 168 5.58E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 Pfam PF01842 ACT domain 296 332 3.4E-8 T 29-03-2018 IPR002912 ACT domain HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 Pfam PF02153 Prephenate dehydrogenase 20 273 2.5E-62 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 Gene3D G3DSA:1.10.3660.10 182 297 2.2E-27 T 29-03-2018 HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 SUPERFAMILY SSF48179 174 283 1.59E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 Gene3D G3DSA:3.40.50.720 3 169 2.8E-21 T 29-03-2018 HVS_RS12670 eae97935949482c814dc2ffb0c5bd830 365 SUPERFAMILY SSF55021 295 348 2.06E-10 T 29-03-2018 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 8 565 2.3E-229 T 29-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 Pfam PF12637 TSCPD domain 612 698 2.2E-11 T 29-03-2018 IPR024434 TSCPD domain HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 Pfam PF02867 Ribonucleotide reductase, barrel domain 86 555 1.9E-161 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 SUPERFAMILY SSF48168 4 84 2.62E-15 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 SUPERFAMILY SSF51998 85 459 4.58E-157 T 29-03-2018 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 SUPERFAMILY SSF51998 491 567 4.58E-157 T 29-03-2018 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 2 83 5.2E-30 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 Gene3D G3DSA:3.20.70.20 1 562 5.4E-200 T 29-03-2018 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 PRINTS PR01183 Ribonucleotide reductase large chain signature 340 362 1.3E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 PRINTS PR01183 Ribonucleotide reductase large chain signature 368 391 1.3E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 PRINTS PR01183 Ribonucleotide reductase large chain signature 161 180 1.3E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 PRINTS PR01183 Ribonucleotide reductase large chain signature 408 435 1.3E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS11785 47773072cf886e76a2335537c9e055ec 767 PRINTS PR01183 Ribonucleotide reductase large chain signature 302 325 1.3E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 Gene3D G3DSA:3.40.50.7700 1 140 1.5E-63 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 136 2.7E-62 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 144 27.33 T 29-03-2018 IPR033747 Class I PurE HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 Pfam PF00731 AIR carboxylase 1 136 3.4E-64 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 PIRSF PIRSF001338 1 141 3.0E-65 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 SMART SM01001 1 144 1.5E-80 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS07950 5cc8ea03e4dc8e8d3a0e0058c2312a4b 144 SUPERFAMILY SSF52255 1 136 3.66E-60 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 HVS_RS11605 c35ca1f55f5a3601ae66b49c3aeaaa59 90 PIRSF PIRSF037258 1 86 4.2E-39 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 HVS_RS11605 c35ca1f55f5a3601ae66b49c3aeaaa59 90 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 81 8.0E-38 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 HVS_RS11605 c35ca1f55f5a3601ae66b49c3aeaaa59 90 Hamap MF_01507 UPF0297 protein . 1 83 24.968 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 HVS_RS00740 67917732e93ecd45555f83a219b368f9 302 SUPERFAMILY SSF53067 6 149 2.78E-16 T 29-03-2018 HVS_RS00740 67917732e93ecd45555f83a219b368f9 302 Gene3D G3DSA:3.30.420.40 162 283 5.2E-5 T 29-03-2018 HVS_RS00740 67917732e93ecd45555f83a219b368f9 302 Pfam PF06406 StbA protein 75 282 1.6E-6 T 29-03-2018 IPR009440 Plasmid segregation protein ParM/StbA HVS_RS00740 67917732e93ecd45555f83a219b368f9 302 Gene3D G3DSA:3.30.420.40 5 161 6.2E-17 T 29-03-2018 HVS_RS00740 67917732e93ecd45555f83a219b368f9 302 SUPERFAMILY SSF53067 156 297 4.75E-13 T 29-03-2018 HVS_RS03470 859bf2a71a69bff8457e863d1ed00a75 263 SUPERFAMILY SSF55383 53 137 4.58E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03470 859bf2a71a69bff8457e863d1ed00a75 263 Gene3D G3DSA:3.30.457.10 21 61 1.6E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03470 859bf2a71a69bff8457e863d1ed00a75 263 Gene3D G3DSA:3.30.457.10 126 260 2.8E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03470 859bf2a71a69bff8457e863d1ed00a75 263 Gene3D G3DSA:3.30.457.10 62 125 1.2E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03470 859bf2a71a69bff8457e863d1ed00a75 263 Pfam PF07833 Copper amine oxidase N-terminal domain 50 142 4.8E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 Hamap MF_00069 Hydroxylamine reductase [hcp]. 3 542 23.267 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 3 540 1.4E-228 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 Gene3D G3DSA:1.20.1270.20 1 136 9.0E-46 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 Gene3D G3DSA:1.20.1270.20 138 220 7.9E-30 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 SUPERFAMILY SSF56821 3 541 1.18E-205 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 Pfam PF03063 Prismane/CO dehydrogenase family 3 538 3.4E-178 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 Gene3D G3DSA:3.40.50.2030 223 367 7.2E-64 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 PIRSF PIRSF000076 3 542 2.0E-259 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS14190 4a7706c2aa6fc1dc385953e40c846a5c 542 Gene3D G3DSA:3.40.50.2030 368 542 3.2E-67 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 HVS_RS05395 0a58bcbe3c646af5ea8eac81552b55fa 227 SUPERFAMILY SSF63848 117 222 3.92E-33 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 HVS_RS05395 0a58bcbe3c646af5ea8eac81552b55fa 227 Gene3D G3DSA:2.160.20.70 107 225 3.3E-39 T 29-03-2018 HVS_RS05395 0a58bcbe3c646af5ea8eac81552b55fa 227 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 120 219 3.7E-33 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 HVS_RS05395 0a58bcbe3c646af5ea8eac81552b55fa 227 Gene3D G3DSA:3.30.750.50 6 96 5.9E-19 T 29-03-2018 HVS_RS05395 0a58bcbe3c646af5ea8eac81552b55fa 227 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 223 22.515 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 HVS_RS05395 0a58bcbe3c646af5ea8eac81552b55fa 227 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 7 221 5.7E-36 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 HVS_RS04790 41dfef15c130164a45de8498cd1cde0a 204 Pfam PF02586 SOS response associated peptidase (SRAP) 1 204 1.3E-42 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) HVS_RS04790 41dfef15c130164a45de8498cd1cde0a 204 Gene3D G3DSA:3.90.1680.10 1 204 2.2E-52 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) HVS_RS04790 41dfef15c130164a45de8498cd1cde0a 204 SUPERFAMILY SSF143081 2 203 4.58E-51 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) HVS_RS11855 d6c4daf7c17196d35e7f048f6fb4f3fa 256 Gene3D G3DSA:3.30.420.40 98 236 2.6E-31 T 29-03-2018 HVS_RS11855 d6c4daf7c17196d35e7f048f6fb4f3fa 256 Gene3D G3DSA:3.30.420.40 2 85 0.0048 T 29-03-2018 HVS_RS11855 d6c4daf7c17196d35e7f048f6fb4f3fa 256 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 246 1.6E-36 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HVS_RS11855 d6c4daf7c17196d35e7f048f6fb4f3fa 256 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 247 1.8E-56 T 29-03-2018 IPR008275 CoA enzyme activase HVS_RS11855 d6c4daf7c17196d35e7f048f6fb4f3fa 256 SUPERFAMILY SSF53067 1 250 2.59E-33 T 29-03-2018 HVS_RS04860 763d317e64fecc20bfefe9f82eff16ac 217 Gene3D G3DSA:3.40.50.2300 1 23 0.0012 T 29-03-2018 HVS_RS04860 763d317e64fecc20bfefe9f82eff16ac 217 Gene3D G3DSA:3.40.50.2300 24 127 6.5E-19 T 29-03-2018 HVS_RS04860 763d317e64fecc20bfefe9f82eff16ac 217 SUPERFAMILY SSF53822 2 104 4.52E-22 T 29-03-2018 IPR028082 Periplasmic binding protein-like I HVS_RS04860 763d317e64fecc20bfefe9f82eff16ac 217 Pfam PF13377 Periplasmic binding protein-like domain 12 103 4.0E-11 T 29-03-2018 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 Pfam PF03143 Elongation factor Tu C-terminal domain 324 411 2.5E-6 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.3E-44 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 Gene3D G3DSA:3.40.50.300 2 202 1.2E-43 T 29-03-2018 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 Gene3D G3DSA:2.40.30.10 203 306 2.0E-25 T 29-03-2018 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 PRINTS PR00315 GTP-binding elongation factor signature 103 114 3.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 PRINTS PR00315 GTP-binding elongation factor signature 9 22 3.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 PRINTS PR00315 GTP-binding elongation factor signature 140 149 3.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 PRINTS PR00315 GTP-binding elongation factor signature 67 75 3.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 PRINTS PR00315 GTP-binding elongation factor signature 87 97 3.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 SUPERFAMILY SSF50465 311 410 3.12E-22 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 Pfam PF03144 Elongation factor Tu domain 2 236 289 1.7E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 Gene3D G3DSA:2.40.30.10 308 412 1.2E-17 T 29-03-2018 HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 SUPERFAMILY SSF52540 4 233 1.84E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 SUPERFAMILY SSF50447 219 307 2.29E-20 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS02690 bf7ae02b70f17d1136326036bcd42e9a 454 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 8 401 7.2E-108 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 HVS_RS05525 e7d2cdfc97109c7dada3e5557cc8a1cf 266 Pfam PF00482 Type II secretion system (T2SS), protein F 94 223 1.3E-6 T 29-03-2018 IPR018076 Type II secretion system F domain HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 SUPERFAMILY SSF47090 186 248 3.66E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Gene3D G3DSA:1.20.1480.30 9 131 5.6E-5 T 29-03-2018 HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Gene3D G3DSA:2.70.70.10 472 635 3.9E-17 T 29-03-2018 HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Pfam PF07486 Cell Wall Hydrolase 698 769 2.3E-7 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Gene3D G3DSA:1.20.141.10 277 384 1.6E-11 T 29-03-2018 HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 SUPERFAMILY SSF47090 272 350 4.55E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Pfam PF01551 Peptidase family M23 507 596 4.0E-13 T 29-03-2018 IPR016047 Peptidase M23 HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 SUPERFAMILY SSF51261 496 596 3.09E-13 T 29-03-2018 IPR011055 Duplicated hybrid motif HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Pfam PF01471 Putative peptidoglycan binding domain 286 349 2.0E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Pfam PF01471 Putative peptidoglycan binding domain 404 456 1.9E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Gene3D G3DSA:1.10.101.10 391 463 4.9E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 SUPERFAMILY SSF47090 404 458 3.14E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03440 f841fc69f956f5af488eb7991b370d61 778 Gene3D G3DSA:1.10.101.10 161 254 1.2E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 Gene3D G3DSA:3.40.50.10380 3 157 5.1E-41 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 SMART SM00919 160 383 3.8E-131 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 Pfam PF03949 Malic enzyme, NAD binding domain 162 382 7.6E-28 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 Pfam PF00390 Malic enzyme, N-terminal domain 18 148 4.1E-28 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 Gene3D G3DSA:3.40.50.720 158 390 4.0E-86 T 29-03-2018 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 PIRSF PIRSF000106 16 390 1.2E-86 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 SUPERFAMILY SSF53223 6 158 7.91E-56 T 29-03-2018 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 SMART SM01274 15 148 4.5E-80 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HVS_RS14660 6b36ad7b8f2111c0bb35e9f220c366f0 390 SUPERFAMILY SSF51735 160 389 8.0E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS02410 140d58411a8043557bc7d541d68e429f 412 SUPERFAMILY SSF51445 141 404 1.02E-11 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS02410 140d58411a8043557bc7d541d68e429f 412 Pfam PF13200 Putative glycosyl hydrolase domain 88 402 5.6E-106 T 29-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 HVS_RS02410 140d58411a8043557bc7d541d68e429f 412 Gene3D G3DSA:3.20.20.80 83 409 9.2E-14 T 29-03-2018 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 494 1.1E-34 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 SMART SM00283 266 541 2.0E-46 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 SMART SM00304 185 237 3.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 Pfam PF00672 HAMP domain 186 233 2.8E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 Gene3D G3DSA:1.10.287.950 196 292 0.0016 T 29-03-2018 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 SUPERFAMILY SSF58104 272 540 5.1E-63 T 29-03-2018 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 SUPERFAMILY SSF58104 205 239 5.1E-63 T 29-03-2018 HVS_RS09400 3cb34a6dddeb05850f42d3d68f4def85 543 Gene3D G3DSA:1.10.287.950 293 543 1.3E-44 T 29-03-2018 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Gene3D G3DSA:1.50.10.10 50 538 9.4E-116 T 29-03-2018 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 925 944 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 SMART SM01067 736 818 1.5E-27 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 SMART SM01067 557 648 0.21 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 ProSitePatterns PS00018 EF-hand calcium-binding domain. 925 937 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 SUPERFAMILY SSF63446 886 951 6.54E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Gene3D G3DSA:2.60.40.710 555 710 5.0E-34 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 SUPERFAMILY SSF49384 556 711 7.33E-36 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Pfam PF00942 Cellulose binding domain 736 817 4.4E-19 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Pfam PF00942 Cellulose binding domain 566 646 6.8E-9 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 SUPERFAMILY SSF49384 734 881 1.67E-37 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 SUPERFAMILY SSF48208 50 538 2.53E-120 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Gene3D G3DSA:2.60.40.710 723 885 2.6E-41 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Gene3D G3DSA:1.10.1330.10 886 951 5.6E-6 T 29-03-2018 HVS_RS04150 417b454f25b0da33766364114d1f8b58 951 Pfam PF00759 Glycosyl hydrolase family 9 52 529 6.0E-111 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07625 85486d8e55997586a45b453c475feba9 237 Gene3D G3DSA:2.40.10.220 96 236 3.5E-14 T 29-03-2018 HVS_RS07625 85486d8e55997586a45b453c475feba9 237 Pfam PF07238 PilZ domain 102 212 1.5E-12 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Gene3D G3DSA:3.90.199.10 38 219 1.4E-84 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 619 662 7.4E-6 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 667 709 2.9E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 767 813 1.5E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 563 611 1.8E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 513 559 6.6E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 718 763 8.9E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 SUPERFAMILY SSF56719 35 496 3.92E-181 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Gene3D G3DSA:1.10.268.10 353 495 4.4E-53 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Gene3D G3DSA:3.30.1360.40 240 336 3.7E-39 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 SMART SM00434 15 473 5.0E-284 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 814 0.0 T 29-03-2018 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 SUPERFAMILY SSF101904 507 823 4.58E-112 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Gene3D G3DSA:2.120.10.90 504 815 8.0E-127 T 29-03-2018 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 9 815 24.954 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HVS_RS16155 bd512adf285187f1509f1d64e38dbe2f 828 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 480 3.2E-162 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00390 574060137d7c9cce74008843fde0874d 138 Pfam PF01894 Uncharacterised protein family UPF0047 20 135 1.1E-35 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS00390 574060137d7c9cce74008843fde0874d 138 SUPERFAMILY SSF111038 1 138 1.96E-44 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS00390 574060137d7c9cce74008843fde0874d 138 PIRSF PIRSF004681 1 138 7.6E-39 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS00390 574060137d7c9cce74008843fde0874d 138 Gene3D G3DSA:2.60.120.460 1 136 6.8E-43 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS00390 574060137d7c9cce74008843fde0874d 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 14 138 1.4E-32 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 Pfam PF07833 Copper amine oxidase N-terminal domain 36 77 5.1E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 Pfam PF07833 Copper amine oxidase N-terminal domain 54 139 9.9E-30 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 Gene3D G3DSA:3.30.457.10 67 127 1.0E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 Gene3D G3DSA:3.30.457.10 16 66 1.2E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 Gene3D G3DSA:3.30.457.10 128 200 2.4E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 SUPERFAMILY SSF55383 60 138 7.19E-24 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02370 bc468fb29107c072d76850270f8208a8 279 Pfam PF07486 Cell Wall Hydrolase 186 277 1.7E-12 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 HVS_RS02685 07869add34ab30f751e367cd603f014c 266 PIRSF PIRSF002936 1 208 3.7E-88 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 HVS_RS02685 07869add34ab30f751e367cd603f014c 266 PIRSF PIRSF002936 204 266 1.2E-19 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 HVS_RS02685 07869add34ab30f751e367cd603f014c 266 SUPERFAMILY SSF52402 2 203 5.91E-62 T 29-03-2018 HVS_RS02685 07869add34ab30f751e367cd603f014c 266 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 25 220 1.2E-47 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 HVS_RS02685 07869add34ab30f751e367cd603f014c 266 Gene3D G3DSA:3.40.50.620 1 263 1.1E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS04180 82ad86f8af405840bc2b99cd4df654a1 392 Gene3D G3DSA:3.40.50.2000 153 360 3.0E-28 T 29-03-2018 HVS_RS04180 82ad86f8af405840bc2b99cd4df654a1 392 Pfam PF13439 Glycosyltransferase Family 4 64 172 8.0E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS04180 82ad86f8af405840bc2b99cd4df654a1 392 SUPERFAMILY SSF53756 10 378 2.77E-41 T 29-03-2018 HVS_RS04180 82ad86f8af405840bc2b99cd4df654a1 392 Pfam PF00534 Glycosyl transferases group 1 180 356 1.8E-17 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 Pfam PF00472 RF-1 domain 210 319 5.0E-44 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 SMART SM00937 63 177 9.7E-65 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 SUPERFAMILY SSF75620 9 351 9.55E-140 T 29-03-2018 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 Gene3D G3DSA:3.30.160.20 207 288 1.7E-34 T 29-03-2018 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 Pfam PF03462 PCRF domain 9 202 4.8E-77 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 Gene3D G3DSA:1.20.58.410 2 94 9.9E-19 T 29-03-2018 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 42.105 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HVS_RS15575 34c89dbaab9d685a9e919425b429e82a 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 352 5.8E-169 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HVS_RS06110 8e76ef7a8ffd3c1c552bd60f0209118f 114 Gene3D G3DSA:3.30.428.10 3 113 5.9E-32 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 HVS_RS06110 8e76ef7a8ffd3c1c552bd60f0209118f 114 Pfam PF01230 HIT domain 11 108 8.1E-27 T 29-03-2018 IPR001310 Histidine triad (HIT) protein HVS_RS06110 8e76ef7a8ffd3c1c552bd60f0209118f 114 SUPERFAMILY SSF54197 1 110 3.56E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 HVS_RS06110 8e76ef7a8ffd3c1c552bd60f0209118f 114 PRINTS PR00332 Histidine triad family signature 94 104 4.1E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein HVS_RS06110 8e76ef7a8ffd3c1c552bd60f0209118f 114 PRINTS PR00332 Histidine triad family signature 26 44 4.1E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein HVS_RS06110 8e76ef7a8ffd3c1c552bd60f0209118f 114 PRINTS PR00332 Histidine triad family signature 5 21 4.1E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein HVS_RS13870 568e323ba416c70ee1e4b7ca2fc9aaa7 418 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 245 410 3.1E-45 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HVS_RS13870 568e323ba416c70ee1e4b7ca2fc9aaa7 418 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 36 412 3.3E-82 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 SUPERFAMILY SSF56601 156 476 3.5E-91 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Gene3D G3DSA:3.30.457.10 11 61 7.7E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Gene3D G3DSA:3.30.457.10 62 132 5.1E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Pfam PF11954 Domain of unknown function (DUF3471) 596 670 1.2E-11 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Pfam PF11954 Domain of unknown function (DUF3471) 497 574 1.8E-11 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Gene3D G3DSA:3.40.710.10 135 485 6.8E-85 T 29-03-2018 HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 SUPERFAMILY SSF55383 53 137 2.48E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Pfam PF00144 Beta-lactamase 157 468 5.8E-69 T 29-03-2018 IPR001466 Beta-lactamase-related HVS_RS06685 5bb6d518b84d117b23b0fbd6b869cef5 681 Pfam PF07833 Copper amine oxidase N-terminal domain 51 142 9.6E-32 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 Gene3D G3DSA:3.30.70.260 1 88 8.4E-27 T 29-03-2018 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 SUPERFAMILY SSF55021 3 77 5.82E-24 T 29-03-2018 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.8E-29 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 159 2.5E-65 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 4.0E-32 T 29-03-2018 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 Pfam PF13710 ACT domain 13 74 3.4E-19 T 29-03-2018 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 Gene3D G3DSA:3.30.70.1150 89 161 9.5E-31 T 29-03-2018 HVS_RS01145 33bd6c0ac1b8a599feb10416cd413965 170 SUPERFAMILY SSF55021 80 163 1.39E-28 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Gene3D G3DSA:2.40.50.140 570 671 1.2E-22 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 280 32.749 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SUPERFAMILY SSF50249 382 466 2.43E-10 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SUPERFAMILY SSF50249 474 576 2.4E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 278 4.0E-96 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Gene3D G3DSA:2.40.50.140 477 558 4.8E-26 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Gene3D G3DSA:2.40.50.140 390 469 4.3E-7 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Pfam PF02401 LytB protein 3 276 3.3E-94 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SUPERFAMILY SSF50249 554 640 9.53E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SUPERFAMILY SSF50249 296 404 1.78E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Pfam PF00575 S1 RNA binding domain 482 552 9.9E-24 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Pfam PF00575 S1 RNA binding domain 400 462 2.7E-5 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Pfam PF00575 S1 RNA binding domain 567 638 5.0E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Pfam PF00575 S1 RNA binding domain 308 379 3.6E-11 T 29-03-2018 IPR003029 S1 domain GO:0003676 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SMART SM00316 567 638 2.5E-22 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SMART SM00316 482 552 3.3E-29 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SMART SM00316 395 463 1.9E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 SMART SM00316 308 379 2.1E-13 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 621 639 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 582 601 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 328 342 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 400 416 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 418 435 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 504 525 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 447 467 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 310 328 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 PRINTS PR00681 Ribosomal protein S1 signature 376 395 1.6E-52 T 29-03-2018 HVS_RS08075 c38231d04daa93f32eda55dde358dc73 685 Gene3D G3DSA:2.40.50.140 286 384 8.5E-17 T 29-03-2018 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Pfam PF00553 Cellulose binding domain 568 654 3.4E-26 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Gene3D G3DSA:2.60.40.290 560 659 3.8E-29 T 29-03-2018 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Gene3D G3DSA:2.60.120.260 256 387 8.8E-27 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Gene3D G3DSA:2.60.120.260 407 534 2.5E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 212 223 - T 29-03-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 PRINTS PR00911 Glycosyl hydrolase family 11 signature 169 174 5.4E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 PRINTS PR00911 Glycosyl hydrolase family 11 signature 174 183 5.4E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 PRINTS PR00911 Glycosyl hydrolase family 11 signature 149 155 5.4E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 PRINTS PR00911 Glycosyl hydrolase family 11 signature 112 121 5.4E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 PRINTS PR00911 Glycosyl hydrolase family 11 signature 122 132 5.4E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 PRINTS PR00911 Glycosyl hydrolase family 11 signature 197 205 5.4E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SUPERFAMILY SSF49785 260 384 7.51E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SUPERFAMILY SSF49384 559 654 3.84E-29 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Pfam PF03422 Carbohydrate binding module (family 6) 267 384 1.6E-30 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Pfam PF03422 Carbohydrate binding module (family 6) 419 531 3.4E-24 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SMART SM00637 563 656 2.1E-32 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Pfam PF00457 Glycosyl hydrolases family 11 44 225 1.1E-66 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SUPERFAMILY SSF49785 412 531 3.06E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 627 640 - T 29-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SUPERFAMILY SSF49899 34 235 4.98E-83 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 122 132 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SMART SM00606 410 533 1.7E-33 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 SMART SM00606 259 384 2.2E-45 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS09105 b1bc8148a547f086693b0ceb47bf245d 659 Gene3D G3DSA:2.60.120.180 28 233 1.5E-86 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 Gene3D G3DSA:1.20.970.10 1 69 1.3E-23 T 29-03-2018 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 Gene3D G3DSA:3.40.1030.10 70 334 1.1E-104 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 Pfam PF00591 Glycosyl transferase family, a/b domain 75 323 3.4E-98 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 65 1.2E-21 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 40.138 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 332 1.1E-133 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 SUPERFAMILY SSF52418 73 333 2.88E-98 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS07595 9f734a4b20c8918f979cfb4826e6370a 347 SUPERFAMILY SSF47648 2 68 2.75E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 HVS_RS14245 2705ac96ea734bba0741b9b78f22c336 279 SMART SM00909 90 179 1.3E-30 T 29-03-2018 IPR019606 GerMN domain HVS_RS14245 2705ac96ea734bba0741b9b78f22c336 279 Pfam PF10646 Sporulation and spore germination 59 175 1.8E-25 T 29-03-2018 IPR019606 GerMN domain HVS_RS16195 65916f8e318b0b92f889c9975eb69fdd 71 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 71 2.0E-20 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor HVS_RS16195 65916f8e318b0b92f889c9975eb69fdd 71 SMART SM01234 2 70 4.8E-42 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor HVS_RS16195 65916f8e318b0b92f889c9975eb69fdd 71 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 71 23.697 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor HVS_RS16195 65916f8e318b0b92f889c9975eb69fdd 71 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 70 1.9E-26 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor HVS_RS16195 65916f8e318b0b92f889c9975eb69fdd 71 Pfam PF01809 Haemolytic domain 3 70 1.9E-30 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 Hamap MF_00023 SsrA-binding protein [smpB]. 1 153 73.926 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 SUPERFAMILY SSF74982 3 132 1.11E-52 T 29-03-2018 IPR023620 Small protein B HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 Pfam PF01668 SmpB protein 9 151 3.6E-62 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 113 4.0E-46 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 Gene3D G3DSA:2.40.280.10 9 127 4.6E-51 T 29-03-2018 IPR023620 Small protein B HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 2.7E-59 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 HVS_RS12805 6c0cf2043a875497626c96b30b8edb98 153 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site HVS_RS11335 212276095c974266a24927e47fd866bc 435 Gene3D G3DSA:1.10.3090.10 132 422 1.3E-68 T 29-03-2018 HVS_RS11335 212276095c974266a24927e47fd866bc 435 SUPERFAMILY SSF81301 6 128 2.51E-34 T 29-03-2018 HVS_RS11335 212276095c974266a24927e47fd866bc 435 Pfam PF01743 Poly A polymerase head domain 27 132 2.7E-26 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HVS_RS11335 212276095c974266a24927e47fd866bc 435 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 160 217 2.9E-16 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 HVS_RS11335 212276095c974266a24927e47fd866bc 435 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 287 427 4.3E-18 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal HVS_RS11335 212276095c974266a24927e47fd866bc 435 Gene3D G3DSA:3.30.460.10 6 131 4.8E-38 T 29-03-2018 HVS_RS11335 212276095c974266a24927e47fd866bc 435 SUPERFAMILY SSF81891 130 429 1.57E-56 T 29-03-2018 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 Pfam PF00460 Flagella basal body rod protein 8 37 4.3E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 2.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 PRINTS PR01005 Flagellar hook-associated protein signature 162 186 2.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 PRINTS PR01005 Flagellar hook-associated protein signature 486 510 2.4E-9 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 SUPERFAMILY SSF64518 172 249 2.88E-14 T 29-03-2018 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 SUPERFAMILY SSF64518 334 412 2.88E-14 T 29-03-2018 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 SUPERFAMILY SSF64518 279 305 2.88E-14 T 29-03-2018 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 SUPERFAMILY SSF64518 443 520 2.88E-14 T 29-03-2018 HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 463 518 6.8E-10 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HVS_RS01385 23453be3299bf7c3435a7245c98d3fcd 522 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 518 6.3E-101 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 66 239 8.7E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 90 103 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 Gene3D G3DSA:1.10.10.60 186 217 4.4E-9 T 29-03-2018 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 PIRSF PIRSF000770 17 244 6.9E-67 T 29-03-2018 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 PRINTS PR00046 Major sigma-70 factor signature 90 103 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 PRINTS PR00046 Major sigma-70 factor signature 188 200 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 PRINTS PR00046 Major sigma-70 factor signature 210 225 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 PRINTS PR00046 Major sigma-70 factor signature 225 236 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 SUPERFAMILY SSF88659 147 241 8.18E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 17 244 2.6E-121 T 29-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 Gene3D G3DSA:3.30.1190.10 218 244 2.3E-8 T 29-03-2018 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 Pfam PF04542 Sigma-70 region 2 66 135 1.4E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 Gene3D G3DSA:1.10.601.10 36 135 1.2E-29 T 29-03-2018 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 Pfam PF04545 Sigma-70, region 4 184 238 1.3E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 210 236 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10320 631d5bd64e8f56175957a7d22f9b2abc 244 SUPERFAMILY SSF88946 26 135 2.2E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 138 5.0E-39 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 Pfam PF01220 Dehydroquinase class II 3 139 4.8E-62 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 PIRSF PIRSF001399 1 142 1.8E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 142 65.803 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 139 6.5E-62 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 Gene3D G3DSA:3.40.50.9100 1 141 9.4E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS08700 5ff5dcbfbc42905bbaaaf0140de7a096 142 SUPERFAMILY SSF52304 3 139 5.36E-59 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 Gene3D G3DSA:2.30.30.30 119 177 1.4E-20 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 SUPERFAMILY SSF50104 122 177 6.45E-18 T 29-03-2018 IPR008991 Translation protein SH3-like domain HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 Pfam PF02357 Transcription termination factor nusG 11 113 1.8E-32 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 Pfam PF00467 KOW motif 127 158 2.3E-8 T 29-03-2018 IPR005824 KOW HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 SUPERFAMILY SSF82679 11 113 1.96E-42 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 9 177 24.421 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 SMART SM00739 123 150 2.0E-5 T 29-03-2018 IPR005824 KOW HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 Gene3D G3DSA:3.30.70.940 9 117 1.3E-44 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.2E-18 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.2E-18 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 PRINTS PR00338 Transcription termination factor NUSG signature 64 76 1.2E-18 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 SMART SM00738 9 117 1.6E-49 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 HVS_RS12980 06deda65baca3af12fdd751428c0475b 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 12 177 2.3E-62 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Pfam PF02237 Biotin protein ligase C terminal domain 282 328 1.9E-6 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 4 329 35.338 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 SUPERFAMILY SSF50037 284 330 5.04E-7 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Pfam PF08279 HTH domain 3 56 1.0E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Gene3D G3DSA:1.10.10.10 2 56 8.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Pfam PF03099 Biotin/lipoate A/B protein ligase family 84 210 1.2E-16 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 SUPERFAMILY SSF55681 69 280 8.82E-57 T 29-03-2018 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Gene3D G3DSA:2.30.30.100 283 330 1.8E-10 T 29-03-2018 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 Gene3D G3DSA:3.30.930.10 57 282 1.1E-61 T 29-03-2018 HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 SUPERFAMILY SSF46785 12 57 8.71E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14675 ab79ce978cd006daabc8050aed8a02a9 335 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 327 1.6E-58 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 SMART SM01217 645 714 6.7E-31 T 29-03-2018 IPR026891 Fibronectin type III-like domain HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 SUPERFAMILY SSF52279 369 611 1.96E-61 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 24 329 3.5E-80 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 Gene3D G3DSA:3.40.50.1700 354 608 9.0E-81 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 369 608 4.0E-63 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 Gene3D G3DSA:2.60.40.10 609 725 3.1E-35 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 Pfam PF14310 Fibronectin type III-like domain 645 714 2.1E-22 T 29-03-2018 IPR026891 Fibronectin type III-like domain HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 PRINTS PR00133 Glycosyl hydrolase family 3 signature 143 159 5.6E-28 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 PRINTS PR00133 Glycosyl hydrolase family 3 signature 73 89 5.6E-28 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 PRINTS PR00133 Glycosyl hydrolase family 3 signature 180 196 5.6E-28 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 PRINTS PR00133 Glycosyl hydrolase family 3 signature 250 268 5.6E-28 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 PRINTS PR00133 Glycosyl hydrolase family 3 signature 97 116 5.6E-28 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 Gene3D G3DSA:3.20.20.300 10 352 3.0E-116 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS12215 7ad94003af5fabab9e2744a2b9e84f70 733 SUPERFAMILY SSF51445 3 368 2.21E-112 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 940 23.403 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Gene3D G3DSA:3.40.50.300 38 115 1.9E-4 T 29-03-2018 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 SUPERFAMILY SSF52540 615 909 2.93E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Gene3D G3DSA:1.10.8.280 284 392 8.8E-33 T 29-03-2018 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 SUPERFAMILY SSF52540 432 571 3.28E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 SUPERFAMILY SSF52540 11 206 3.28E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Gene3D G3DSA:3.30.190.20 129 247 2.1E-44 T 29-03-2018 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Gene3D G3DSA:3.40.50.300 393 608 1.0E-27 T 29-03-2018 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Gene3D G3DSA:3.40.50.300 6 37 0.0059 T 29-03-2018 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 925 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Gene3D G3DSA:3.40.50.300 610 941 4.7E-59 T 29-03-2018 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 Pfam PF00005 ABC transporter 624 860 2.6E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS05255 0cd654abe8c53938437cd065ebafd40d 949 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS02835 9c02b7d5d62a108b4eb0f1fa93c2177d 276 Gene3D G3DSA:1.10.150.130 1 93 7.0E-13 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal HVS_RS02835 9c02b7d5d62a108b4eb0f1fa93c2177d 276 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 1 83 5.3E-10 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HVS_RS02835 9c02b7d5d62a108b4eb0f1fa93c2177d 276 SUPERFAMILY SSF56349 2 274 8.24E-41 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HVS_RS02835 9c02b7d5d62a108b4eb0f1fa93c2177d 276 Pfam PF00589 Phage integrase family 111 264 5.8E-29 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS02835 9c02b7d5d62a108b4eb0f1fa93c2177d 276 Gene3D G3DSA:1.10.443.10 108 274 1.2E-34 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 SUPERFAMILY SSF49785 256 382 4.25E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS13100 79527171b92ac738942b2a513d449c19 672 PRINTS PR00911 Glycosyl hydrolase family 11 signature 162 167 6.5E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 PRINTS PR00911 Glycosyl hydrolase family 11 signature 115 125 6.5E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 PRINTS PR00911 Glycosyl hydrolase family 11 signature 142 148 6.5E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 PRINTS PR00911 Glycosyl hydrolase family 11 signature 190 198 6.5E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 PRINTS PR00911 Glycosyl hydrolase family 11 signature 105 114 6.5E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 PRINTS PR00911 Glycosyl hydrolase family 11 signature 167 176 6.5E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Gene3D G3DSA:2.60.120.260 253 383 1.6E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS13100 79527171b92ac738942b2a513d449c19 672 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 115 125 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Gene3D G3DSA:3.40.50.1110 465 670 2.8E-30 T 29-03-2018 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 486 656 2.3E-16 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS13100 79527171b92ac738942b2a513d449c19 672 SUPERFAMILY SSF63446 397 465 1.7E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Pfam PF00404 Dockerin type I repeat 435 455 1.4E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Pfam PF03422 Carbohydrate binding module (family 6) 263 382 2.6E-31 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 SUPERFAMILY SSF49899 27 227 2.04E-83 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS13100 79527171b92ac738942b2a513d449c19 672 SMART SM00606 255 382 2.5E-47 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Gene3D G3DSA:2.60.120.180 21 226 2.1E-87 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Pfam PF00457 Glycosyl hydrolases family 11 37 218 1.0E-66 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 435 454 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 Gene3D G3DSA:1.10.1330.10 397 464 8.7E-6 T 29-03-2018 HVS_RS13100 79527171b92ac738942b2a513d449c19 672 SUPERFAMILY SSF52266 471 668 2.11E-30 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS08530 53ae268596c46df657255285105dac3b 265 Pfam PF00037 4Fe-4S binding domain 220 243 7.1E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS08530 53ae268596c46df657255285105dac3b 265 Gene3D G3DSA:3.30.70.20 153 207 1.1E-5 T 29-03-2018 HVS_RS08530 53ae268596c46df657255285105dac3b 265 SUPERFAMILY SSF52218 1 111 2.0E-22 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS08530 53ae268596c46df657255285105dac3b 265 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 227 238 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS08530 53ae268596c46df657255285105dac3b 265 Gene3D G3DSA:3.30.70.20 228 258 9.0E-5 T 29-03-2018 HVS_RS08530 53ae268596c46df657255285105dac3b 265 SUPERFAMILY SSF54862 181 248 8.63E-16 T 29-03-2018 HVS_RS08530 53ae268596c46df657255285105dac3b 265 Gene3D G3DSA:3.30.70.20 208 227 9.6E-10 T 29-03-2018 HVS_RS08530 53ae268596c46df657255285105dac3b 265 Gene3D G3DSA:3.40.50.360 2 151 2.4E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 Gene3D G3DSA:3.20.20.70 146 396 4.6E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 Pfam PF12544 Lysine-2,3-aminomutase 354 407 7.7E-16 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 TIGRFAM TIGR00238 TIGR00238: KamA family protein 49 375 1.4E-99 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 TIGRFAM TIGR04368 Glu_2_3_NH3_mut: glutamate 2,3-aminomutase 6 408 2.4E-204 T 29-03-2018 IPR030801 Glutamate 2,3-aminomutase GO:0016869 HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 Pfam PF04055 Radical SAM superfamily 161 311 1.6E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 SUPERFAMILY SSF102114 151 390 3.53E-31 T 29-03-2018 HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 PIRSF PIRSF004911 15 415 1.5E-134 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HVS_RS09585 3919025f25e47e5711fdc6debe7e1cce 417 Pfam PF13394 4Fe-4S single cluster domain 163 231 7.8E-6 T 29-03-2018 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Pfam PF12838 4Fe-4S dicluster domain 216 259 1.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 5 101 1.4E-22 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Gene3D G3DSA:3.30.70.20 150 175 1.1E-10 T 29-03-2018 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Pfam PF04060 Putative Fe-S cluster 45 77 2.1E-12 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 245 256 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Gene3D G3DSA:3.30.70.20 176 224 1.5E-11 T 29-03-2018 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Gene3D G3DSA:3.30.70.20 225 265 8.7E-15 T 29-03-2018 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Pfam PF13187 4Fe-4S dicluster domain 142 186 1.3E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 Gene3D G3DSA:3.30.70.20 91 149 0.011 T 29-03-2018 HVS_RS01645 4a6b01f397b0deb493da23afebd0609f 266 SUPERFAMILY SSF54862 135 262 1.93E-25 T 29-03-2018 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 45 419 8.9E-87 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 6 432 30.979 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 Gene3D G3DSA:1.20.1640.10 227 423 3.7E-28 T 29-03-2018 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 SUPERFAMILY SSF82866 229 421 8.89E-36 T 29-03-2018 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 Pfam PF02355 Protein export membrane protein 252 421 1.5E-19 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 PRINTS PR00702 Acriflavin resistance protein family signature 321 345 4.0E-6 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 PRINTS PR00702 Acriflavin resistance protein family signature 396 419 4.0E-6 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 PRINTS PR00702 Acriflavin resistance protein family signature 268 291 4.0E-6 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 HVS_RS09330 28f2ab9958c80da43aacca8143b293b5 443 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 177 412 1.9E-61 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 SUPERFAMILY SSF46894 126 226 2.08E-32 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 Gene3D G3DSA:1.10.10.10 122 228 8.0E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 SMART SM00862 150 225 2.2E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 SMART SM00448 5 115 3.3E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 Gene3D G3DSA:3.40.50.2300 1 121 2.4E-36 T 29-03-2018 HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 8.6E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 Pfam PF00072 Response regulator receiver domain 7 115 1.8E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10920 e06884cafb13e4213efaecc6c97107e3 228 SUPERFAMILY SSF52172 2 123 3.56E-42 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS03820 8682ce7f4b4b3d10365cb1d1a79bf5dc 395 SMART SM00306 163 257 2.1E-13 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03820 8682ce7f4b4b3d10365cb1d1a79bf5dc 395 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 165 235 5.8E-6 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03820 8682ce7f4b4b3d10365cb1d1a79bf5dc 395 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 276 300 5.5E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS03820 8682ce7f4b4b3d10365cb1d1a79bf5dc 395 Pfam PF07591 Pretoxin HINT domain 171 300 3.6E-30 T 29-03-2018 HVS_RS03820 8682ce7f4b4b3d10365cb1d1a79bf5dc 395 Gene3D G3DSA:2.170.16.10 151 299 3.8E-39 T 29-03-2018 HVS_RS03820 8682ce7f4b4b3d10365cb1d1a79bf5dc 395 SUPERFAMILY SSF51294 165 298 9.16E-27 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 SUPERFAMILY SSF48452 96 254 3.84E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 Gene3D G3DSA:1.25.40.10 516 639 9.6E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 Gene3D G3DSA:1.25.40.10 640 799 0.0034 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 SUPERFAMILY SSF48452 537 677 2.85E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 SMART SM00028 200 233 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 SMART SM00028 132 165 8.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 SMART SM00028 581 614 0.019 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 Gene3D G3DSA:1.25.40.10 182 508 4.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS01725 42f2a91f41d55a4685d34e3b7641b774 851 Gene3D G3DSA:1.25.40.10 4 181 9.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS00115 82b9a9bda440f0ad6139ee4a707a970d 102 Gene3D G3DSA:3.30.70.20 66 102 5.6E-13 T 29-03-2018 HVS_RS00115 82b9a9bda440f0ad6139ee4a707a970d 102 Pfam PF12838 4Fe-4S dicluster domain 49 95 3.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS00115 82b9a9bda440f0ad6139ee4a707a970d 102 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS00115 82b9a9bda440f0ad6139ee4a707a970d 102 Gene3D G3DSA:3.30.70.20 16 65 1.9E-7 T 29-03-2018 HVS_RS00115 82b9a9bda440f0ad6139ee4a707a970d 102 SUPERFAMILY SSF54862 12 101 5.23E-24 T 29-03-2018 HVS_RS00115 82b9a9bda440f0ad6139ee4a707a970d 102 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 24 101 1.1E-30 T 29-03-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 HVS_RS03255 0b1a9ea7ab9ec1cfeb86ab9bbcfe252a 323 Gene3D G3DSA:3.40.50.1980 41 156 1.6E-31 T 29-03-2018 HVS_RS03255 0b1a9ea7ab9ec1cfeb86ab9bbcfe252a 323 Gene3D G3DSA:3.40.50.1980 157 313 9.8E-32 T 29-03-2018 HVS_RS03255 0b1a9ea7ab9ec1cfeb86ab9bbcfe252a 323 SUPERFAMILY SSF53807 40 310 1.96E-59 T 29-03-2018 HVS_RS03255 0b1a9ea7ab9ec1cfeb86ab9bbcfe252a 323 Pfam PF01497 Periplasmic binding protein 62 288 3.9E-38 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HVS_RS08395 55b175bcfd768a60bc557ba2d2511765 308 SUPERFAMILY SSF56059 89 296 2.79E-42 T 29-03-2018 HVS_RS08395 55b175bcfd768a60bc557ba2d2511765 308 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 25 292 6.9E-64 T 29-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 HVS_RS08395 55b175bcfd768a60bc557ba2d2511765 308 Gene3D G3DSA:3.30.470.20 176 283 4.6E-27 T 29-03-2018 HVS_RS08395 55b175bcfd768a60bc557ba2d2511765 308 Gene3D G3DSA:3.30.1490.20 103 175 3.8E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS08395 55b175bcfd768a60bc557ba2d2511765 308 Pfam PF08443 RimK-like ATP-grasp domain 98 292 1.1E-41 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 HVS_RS08395 55b175bcfd768a60bc557ba2d2511765 308 Gene3D G3DSA:3.40.50.20 14 102 1.1E-8 T 29-03-2018 HVS_RS10965 ead9c560d3050250036bdf1f1d42f3ec 498 Pfam PF07508 Recombinase 169 273 4.9E-25 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 HVS_RS10965 ead9c560d3050250036bdf1f1d42f3ec 498 SMART SM00857 1 146 1.0E-22 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS10965 ead9c560d3050250036bdf1f1d42f3ec 498 Pfam PF00239 Resolvase, N terminal domain 1 145 1.3E-17 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS10965 ead9c560d3050250036bdf1f1d42f3ec 498 SUPERFAMILY SSF53041 1 146 2.75E-22 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS10965 ead9c560d3050250036bdf1f1d42f3ec 498 Pfam PF13408 Recombinase zinc beta ribbon domain 288 344 1.2E-11 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain HVS_RS10965 ead9c560d3050250036bdf1f1d42f3ec 498 Gene3D G3DSA:3.40.50.1390 1 156 2.5E-28 T 29-03-2018 HVS_RS06875 5c501ed04ef9622bcf9f07079603d78e 126 Pfam PF01042 Endoribonuclease L-PSP 9 125 2.1E-48 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family HVS_RS06875 5c501ed04ef9622bcf9f07079603d78e 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 29-03-2018 IPR019897 RidA, conserved site HVS_RS06875 5c501ed04ef9622bcf9f07079603d78e 126 Gene3D G3DSA:3.30.1330.40 1 126 7.5E-51 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HVS_RS06875 5c501ed04ef9622bcf9f07079603d78e 126 SUPERFAMILY SSF55298 2 126 3.77E-49 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HVS_RS06875 5c501ed04ef9622bcf9f07079603d78e 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 125 1.3E-58 T 29-03-2018 IPR006056 RidA family HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 1.4E-26 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 1.4E-49 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 317 6.2E-126 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 8 317 51.029 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 SUPERFAMILY SSF53271 73 308 9.07E-68 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 Gene3D G3DSA:3.40.50.2020 5 161 4.4E-68 T 29-03-2018 HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 Gene3D G3DSA:3.40.50.2020 162 295 3.8E-43 T 29-03-2018 HVS_RS00530 2afb71dc210338f3927a892bc2e4f83c 320 SMART SM01400 8 124 1.5E-78 T 29-03-2018 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 Pfam PF02310 B12 binding domain 6 123 2.5E-17 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 Gene3D G3DSA:3.40.50.280 2 122 1.6E-8 T 29-03-2018 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 SUPERFAMILY SSF102114 172 416 5.89E-45 T 29-03-2018 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 SMART SM00729 178 391 6.3E-26 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 Pfam PF13311 Protein of unknown function (DUF4080) 372 558 2.3E-55 T 29-03-2018 IPR025288 Domain of unknown function DUF4080 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 Gene3D G3DSA:3.20.20.70 123 423 1.1E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS05875 de5a6b57bb8d098cdac578455cedd3d6 581 Pfam PF04055 Radical SAM superfamily 183 343 6.3E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS03875 4b0bee2ca1dab15fbd06d88816e9b7f1 458 SMART SM00885 297 449 1.3E-39 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS03875 4b0bee2ca1dab15fbd06d88816e9b7f1 458 Pfam PF08706 D5 N terminal like 297 447 9.8E-30 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 232 257 3.1E-67 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 187 207 3.1E-67 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 76 96 3.1E-67 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 96 115 3.1E-67 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 208 229 3.1E-67 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 57 76 3.1E-67 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 235 247 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 155 167 6.3E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 115 127 6.3E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 180 192 6.3E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 127 141 6.3E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 248 258 6.3E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 55 64 6.3E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 Pfam PF00813 FliP family 59 254 1.9E-81 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 187 202 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 HVS_RS10180 2433eae4c69af10db7d3da3527b89d2c 260 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 59 258 1.2E-82 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 HVS_RS09845 06125681011a902f93effcdd2e1b1bb9 396 SUPERFAMILY SSF53383 25 392 5.5E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS09845 06125681011a902f93effcdd2e1b1bb9 396 Gene3D G3DSA:3.90.1150.10 276 396 8.3E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS09845 06125681011a902f93effcdd2e1b1bb9 396 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 26 386 2.8E-158 T 29-03-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family HVS_RS09845 06125681011a902f93effcdd2e1b1bb9 396 PIRSF PIRSF000390 22 396 7.7E-94 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HVS_RS09845 06125681011a902f93effcdd2e1b1bb9 396 Gene3D G3DSA:3.40.640.10 26 275 5.0E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS09845 06125681011a902f93effcdd2e1b1bb9 396 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 37 391 1.7E-88 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HVS_RS02150 4449cf8418028e136f573840a4f67148 57 SMART SM00862 1 53 0.0019 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS02150 4449cf8418028e136f573840a4f67148 57 Pfam PF00486 Transcriptional regulatory protein, C terminal 1 53 1.7E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS02150 4449cf8418028e136f573840a4f67148 57 SUPERFAMILY SSF46894 1 54 9.92E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS02150 4449cf8418028e136f573840a4f67148 57 Gene3D G3DSA:1.10.10.10 1 56 2.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 SUPERFAMILY SSF48179 267 360 1.02E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 71 479 2.9E-130 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 SUPERFAMILY SSF52413 373 482 1.7E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 268 358 2.7E-29 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 SMART SM00984 385 483 5.2E-31 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 Gene3D G3DSA:3.40.50.720 291 488 1.2E-56 T 29-03-2018 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 385 481 2.0E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 Gene3D G3DSA:3.40.50.720 51 265 4.0E-36 T 29-03-2018 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 PIRSF PIRSF500136 59 490 1.5E-145 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 PIRSF PIRSF000124 69 489 2.1E-63 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 SUPERFAMILY SSF51735 71 261 3.95E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 71 247 1.8E-43 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 HVS_RS09935 e8bcfb85630ba1abb781bc736ca11300 491 Gene3D G3DSA:1.20.5.170 267 290 1.4E-10 T 29-03-2018 HVS_RS15840 26c82396a3a47d00e5c28b464937b33b 241 Gene3D G3DSA:3.30.457.10 18 69 3.8E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15840 26c82396a3a47d00e5c28b464937b33b 241 Gene3D G3DSA:3.30.457.10 70 225 2.7E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15840 26c82396a3a47d00e5c28b464937b33b 241 SUPERFAMILY SSF55383 50 81 1.12E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15840 26c82396a3a47d00e5c28b464937b33b 241 Pfam PF07833 Copper amine oxidase N-terminal domain 56 92 7.9E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 PIRSF PIRSF000498 1 211 1.8E-78 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 SUPERFAMILY SSF63380 1 92 1.11E-27 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 SUPERFAMILY SSF63380 92 194 5.78E-32 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 Gene3D G3DSA:2.40.30.20 93 190 1.1E-30 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 Gene3D G3DSA:2.40.30.20 1 88 4.2E-31 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 194 1.2E-73 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 Pfam PF00677 Lumazine binding domain 3 86 3.2E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05440 ed27bb4598468f677e9cecae49936dc9 217 Pfam PF00677 Lumazine binding domain 99 183 1.4E-21 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS06480 7fa73466b2d6f518762af7a1a4112ccf 294 Hamap MF_01499 Diadenylate cyclase [dacA]. 15 275 33.633 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 HVS_RS06480 7fa73466b2d6f518762af7a1a4112ccf 294 PIRSF PIRSF004793 20 289 5.9E-90 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 HVS_RS06480 7fa73466b2d6f518762af7a1a4112ccf 294 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 28 275 8.4E-84 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 HVS_RS06480 7fa73466b2d6f518762af7a1a4112ccf 294 Gene3D G3DSA:3.40.1700.10 132 260 5.7E-37 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HVS_RS06480 7fa73466b2d6f518762af7a1a4112ccf 294 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 139 255 2.7E-45 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HVS_RS06480 7fa73466b2d6f518762af7a1a4112ccf 294 SUPERFAMILY SSF143597 58 261 6.02E-66 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HVS_RS10530 79a223f8b0abdde8b015e2640f2d7cb5 91 Gene3D G3DSA:3.30.1230.10 1 91 2.7E-35 T 29-03-2018 IPR007393 Domain of unknown function DUF448 HVS_RS10530 79a223f8b0abdde8b015e2640f2d7cb5 91 SUPERFAMILY SSF64376 4 85 2.09E-29 T 29-03-2018 IPR007393 Domain of unknown function DUF448 HVS_RS10530 79a223f8b0abdde8b015e2640f2d7cb5 91 Pfam PF04296 Protein of unknown function (DUF448) 9 82 5.1E-33 T 29-03-2018 IPR007393 Domain of unknown function DUF448 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 Gene3D G3DSA:3.30.465.10 93 204 8.0E-37 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 304 94.316 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 202 301 7.2E-34 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 Gene3D G3DSA:3.90.78.10 205 301 1.4E-32 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 Pfam PF01565 FAD binding domain 38 167 4.4E-26 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 302 1.9E-81 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 SUPERFAMILY SSF56194 198 303 9.81E-41 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 SUPERFAMILY SSF56176 24 211 1.88E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HVS_RS12105 8e74a065067d60b0c47dcea80dd7105d 304 Gene3D G3DSA:3.30.43.10 15 87 7.2E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 SUPERFAMILY SSF53187 155 324 1.23E-70 T 29-03-2018 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 SUPERFAMILY SSF53187 1 75 1.23E-70 T 29-03-2018 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 SUPERFAMILY SSF101821 65 144 1.83E-14 T 29-03-2018 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 Pfam PF05343 M42 glutamyl aminopeptidase 42 319 4.0E-97 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 Gene3D G3DSA:2.40.30.40 65 141 3.8E-15 T 29-03-2018 IPR023367 Peptidase M42, domain 2 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 PIRSF PIRSF001123 1 330 3.0E-109 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS07575 34b6f99a194e6d730f0da585451ee242 330 Gene3D G3DSA:3.40.630.10 142 329 4.3E-49 T 29-03-2018 HVS_RS11260 c70f5e96cd71d5649f063351aedce79f 190 Pfam PF05103 DivIVA protein 4 126 1.4E-5 T 29-03-2018 IPR007793 DivIVA family HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 SMART SM00858 292 350 2.1E-11 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 Pfam PF08666 SAF domain 293 349 1.4E-11 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 Gene3D G3DSA:3.20.20.70 5 279 7.5E-94 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 SUPERFAMILY SSF51269 289 349 2.51E-18 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 Pfam PF03102 NeuB family 39 277 1.2E-96 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 SUPERFAMILY SSF51569 5 304 1.17E-98 T 29-03-2018 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 19 344 6.4E-152 T 29-03-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 HVS_RS04415 ac90f0d0803d3eb80eb3bb559325ebe9 350 Gene3D G3DSA:3.90.1210.10 280 350 1.8E-24 T 29-03-2018 HVS_RS14535 e993640754072b6c967773c84bdb082f 415 SUPERFAMILY SSF53383 25 413 5.0E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS14535 e993640754072b6c967773c84bdb082f 415 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 260 269 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 HVS_RS14535 e993640754072b6c967773c84bdb082f 415 Pfam PF00155 Aminotransferase class I and II 65 405 8.9E-64 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS14535 e993640754072b6c967773c84bdb082f 415 Gene3D G3DSA:3.40.640.10 82 297 6.5E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS14535 e993640754072b6c967773c84bdb082f 415 Gene3D G3DSA:3.90.1150.10 298 415 2.0E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 Pfam PF00664 ABC transporter transmembrane region 37 311 4.9E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 SUPERFAMILY SSF90123 23 345 2.88E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 SUPERFAMILY SSF52540 348 595 3.2E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 Gene3D G3DSA:1.20.1560.10 15 346 1.9E-56 T 29-03-2018 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 Pfam PF00005 ABC transporter 375 524 9.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 Gene3D G3DSA:3.40.50.300 347 598 3.2E-75 T 29-03-2018 HVS_RS05575 0c87b36fd8add1a6eabc95236e3068a1 611 SMART SM00382 384 585 3.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04000 c19ce79cafc7bf55c8d13387a2cf28ae 353 Gene3D G3DSA:2.170.16.10 109 260 1.5E-37 T 29-03-2018 HVS_RS04000 c19ce79cafc7bf55c8d13387a2cf28ae 353 SMART SM00306 124 218 3.5E-11 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04000 c19ce79cafc7bf55c8d13387a2cf28ae 353 SUPERFAMILY SSF51294 126 261 1.09E-25 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04000 c19ce79cafc7bf55c8d13387a2cf28ae 353 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 126 196 5.2E-6 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04000 c19ce79cafc7bf55c8d13387a2cf28ae 353 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 237 261 4.8E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS04000 c19ce79cafc7bf55c8d13387a2cf28ae 353 Pfam PF07591 Pretoxin HINT domain 132 261 1.2E-29 T 29-03-2018 HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 SMART SM00257 25 70 3.9E-18 T 29-03-2018 IPR018392 LysM domain HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 SUPERFAMILY SSF54106 25 70 5.62E-12 T 29-03-2018 IPR018392 LysM domain HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 Pfam PF01476 LysM domain 26 70 2.2E-17 T 29-03-2018 IPR018392 LysM domain HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 76 201 3.1E-59 T 29-03-2018 IPR014258 CAP domain, YkwD-like HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 28 70 2.3E-24 T 29-03-2018 IPR014248 Spore coat assembly protein SafA HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 Gene3D G3DSA:3.40.33.10 73 202 7.8E-19 T 29-03-2018 IPR014044 CAP domain HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 Gene3D G3DSA:3.10.350.10 23 71 2.6E-19 T 29-03-2018 HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 SUPERFAMILY SSF55797 76 199 3.01E-27 T 29-03-2018 IPR014044 CAP domain HVS_RS05210 83099e35233cd12d8ccc1dc3badd4b9b 202 Pfam PF00188 Cysteine-rich secretory protein family 84 199 6.5E-18 T 29-03-2018 IPR014044 CAP domain HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Pfam PF01471 Putative peptidoglycan binding domain 204 260 1.5E-5 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Pfam PF01471 Putative peptidoglycan binding domain 300 357 1.5E-5 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 SUPERFAMILY SSF53955 399 488 9.48E-14 T 29-03-2018 IPR023346 Lysozyme-like domain HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Gene3D G3DSA:1.10.530.10 393 496 9.5E-14 T 29-03-2018 HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Gene3D G3DSA:1.10.101.10 193 269 4.5E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Gene3D G3DSA:1.10.101.10 290 365 2.0E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Gene3D G3DSA:1.20.1480.30 23 146 7.9E-5 T 29-03-2018 HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 SUPERFAMILY SSF47090 299 358 7.85E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 Pfam PF01464 Transglycosylase SLT domain 407 492 8.4E-10 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 HVS_RS03545 526f4e57c6c650c9539ecc461e56cfa5 796 SUPERFAMILY SSF47090 192 262 4.4E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS08505 69cbcb1fd068f3a9fb966057f9044525 288 SUPERFAMILY SSF52540 3 223 3.41E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08505 69cbcb1fd068f3a9fb966057f9044525 288 Pfam PF00005 ABC transporter 19 158 4.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS08505 69cbcb1fd068f3a9fb966057f9044525 288 SMART SM00382 28 207 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08505 69cbcb1fd068f3a9fb966057f9044525 288 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS08505 69cbcb1fd068f3a9fb966057f9044525 288 Gene3D G3DSA:3.40.50.300 1 272 7.8E-51 T 29-03-2018 HVS_RS01520 410da1b5ce59449afa56735a77c99117 494 Pfam PF00665 Integrase core domain 128 250 1.3E-9 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS01520 410da1b5ce59449afa56735a77c99117 494 Gene3D G3DSA:1.10.10.60 4 83 8.6E-7 T 29-03-2018 HVS_RS01520 410da1b5ce59449afa56735a77c99117 494 Gene3D G3DSA:3.30.420.10 128 286 6.0E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS11850 f0ce61fd469ff9042660dd20f316af0a 219 Gene3D G3DSA:3.40.50.620 1 219 3.3E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS11850 f0ce61fd469ff9042660dd20f316af0a 219 PIRSF PIRSF006293 1 219 1.0E-79 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HVS_RS11850 f0ce61fd469ff9042660dd20f316af0a 219 Pfam PF06508 Queuosine biosynthesis protein QueC 3 210 5.5E-77 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HVS_RS11850 f0ce61fd469ff9042660dd20f316af0a 219 SUPERFAMILY SSF52402 1 218 2.51E-64 T 29-03-2018 HVS_RS11850 f0ce61fd469ff9042660dd20f316af0a 219 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 203 1.4E-64 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HVS_RS11850 f0ce61fd469ff9042660dd20f316af0a 219 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 216 53.632 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 SUPERFAMILY SSF52540 4 554 2.83E-248 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 Gene3D G3DSA:3.40.50.300 235 442 5.7E-75 T 29-03-2018 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 Gene3D G3DSA:3.40.50.300 12 234 1.1E-92 T 29-03-2018 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 Gene3D G3DSA:3.10.410.10 444 532 1.4E-39 T 29-03-2018 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 49.381 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HVS_RS00155 6feaf01f41f963818bf9cb67ede997e2 556 Pfam PF01268 Formate--tetrahydrofolate ligase 3 556 2.2E-275 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HVS_RS10620 9a223e034829f4dba542931726344936 794 Gene3D G3DSA:3.40.50.300 291 518 9.9E-34 T 29-03-2018 HVS_RS10620 9a223e034829f4dba542931726344936 794 SUPERFAMILY SSF52540 292 513 4.13E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10620 9a223e034829f4dba542931726344936 794 SMART SM00534 328 513 7.7E-76 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS10620 9a223e034829f4dba542931726344936 794 SUPERFAMILY SSF160443 716 792 6.28E-10 T 29-03-2018 IPR002625 Smr domain HVS_RS10620 9a223e034829f4dba542931726344936 794 Pfam PF01713 Smr domain 718 793 7.2E-21 T 29-03-2018 IPR002625 Smr domain HVS_RS10620 9a223e034829f4dba542931726344936 794 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 792 2.7E-229 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HVS_RS10620 9a223e034829f4dba542931726344936 794 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS10620 9a223e034829f4dba542931726344936 794 Pfam PF00488 MutS domain V 331 513 2.0E-35 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HVS_RS10620 9a223e034829f4dba542931726344936 794 SMART SM00533 10 315 9.8E-27 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HVS_RS10620 9a223e034829f4dba542931726344936 794 PIRSF PIRSF005814 1 793 1.8E-261 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HVS_RS10620 9a223e034829f4dba542931726344936 794 Gene3D G3DSA:3.40.50.300 6 268 0.068 T 29-03-2018 HVS_RS10620 9a223e034829f4dba542931726344936 794 SMART SM00463 715 793 3.7E-20 T 29-03-2018 IPR002625 Smr domain HVS_RS10620 9a223e034829f4dba542931726344936 794 SUPERFAMILY SSF48334 17 289 3.14E-24 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HVS_RS10620 9a223e034829f4dba542931726344936 794 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 792 21.325 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 SUPERFAMILY SSF51445 74 363 1.1E-21 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 Pfam PF00395 S-layer homology domain 607 649 2.8E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 Pfam PF00395 S-layer homology domain 557 591 4.7E-6 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 Pfam PF00395 S-layer homology domain 675 716 6.2E-6 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 Gene3D G3DSA:3.20.20.80 63 428 8.9E-39 T 29-03-2018 HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 Gene3D G3DSA:2.60.40.10 443 551 1.3E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS11780 98961ba2ebd4638b5bb11532a906bc4b 727 Pfam PF02638 Glycosyl hydrolase-like 10 50 372 8.6E-88 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 62 6.0E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 Pfam PF02609 Exonuclease VII small subunit 8 58 2.3E-18 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 SUPERFAMILY SSF116842 2 69 2.88E-19 T 29-03-2018 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 PIRSF PIRSF006488 1 75 8.6E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 14.631 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 5 48 3.0E-9 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS08615 0950d3c48880516ed01c9b5d6fd3d007 75 Gene3D G3DSA:1.10.287.1040 5 73 8.9E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 294 306 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 SMART SM01240 8 470 0.0 T 29-03-2018 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 9 483 86.922 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 SMART SM00116 157 205 8.5E-12 T 29-03-2018 IPR000644 CBS domain HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 SMART SM00116 97 144 3.2E-7 T 29-03-2018 IPR000644 CBS domain HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 Gene3D G3DSA:3.20.20.70 2 480 5.7E-118 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 SUPERFAMILY SSF51412 5 91 2.22E-129 T 29-03-2018 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 SUPERFAMILY SSF51412 216 474 2.22E-129 T 29-03-2018 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 470 4.1E-170 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 Pfam PF00571 CBS domain 97 140 5.8E-8 T 29-03-2018 IPR000644 CBS domain HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 Pfam PF00571 CBS domain 150 204 2.2E-10 T 29-03-2018 IPR000644 CBS domain HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 SUPERFAMILY SSF54631 66 204 1.25E-30 T 29-03-2018 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 PIRSF PIRSF000130 1 485 3.3E-217 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HVS_RS15210 c45248539d82a98fd6f2d53acb8e7a07 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 9 451 3.0E-201 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 HVS_RS15565 ee389222e3d967bee67b89b14061ea2f 350 Pfam PF01300 Telomere recombination 24 199 3.1E-56 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 HVS_RS15565 ee389222e3d967bee67b89b14061ea2f 350 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 210 5.7E-70 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 HVS_RS15565 ee389222e3d967bee67b89b14061ea2f 350 Gene3D G3DSA:3.90.870.10 2 215 2.6E-78 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain HVS_RS15565 ee389222e3d967bee67b89b14061ea2f 350 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 344 1.2E-26 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain HVS_RS15565 ee389222e3d967bee67b89b14061ea2f 350 PIRSF PIRSF004930 1 350 1.4E-128 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 HVS_RS15565 ee389222e3d967bee67b89b14061ea2f 350 SUPERFAMILY SSF55821 5 212 5.19E-64 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain HVS_RS08515 bce086eb790e30621d09146eac2b14ff 373 Gene3D G3DSA:2.130.10.30 27 195 1.5E-7 T 29-03-2018 HVS_RS08515 bce086eb790e30621d09146eac2b14ff 373 Gene3D G3DSA:2.130.10.30 196 277 6.7E-6 T 29-03-2018 HVS_RS08515 bce086eb790e30621d09146eac2b14ff 373 Gene3D G3DSA:3.10.100.10 311 353 0.0013 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS08515 bce086eb790e30621d09146eac2b14ff 373 Gene3D G3DSA:3.10.100.10 278 310 0.44 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS08515 bce086eb790e30621d09146eac2b14ff 373 SUPERFAMILY SSF50985 107 350 1.12E-17 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 SUPERFAMILY SSF51430 1 316 1.96E-61 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 Gene3D G3DSA:3.20.20.100 1 295 5.1E-54 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.1E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.1E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 PRINTS PR00069 Aldo-keto reductase signature 135 152 1.1E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 350 361 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 Gene3D G3DSA:3.30.70.20 357 389 1.1E-4 T 29-03-2018 HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 Gene3D G3DSA:3.30.70.20 296 356 4.7E-8 T 29-03-2018 HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 Pfam PF00248 Aldo/keto reductase family 16 247 2.7E-32 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 SUPERFAMILY SSF46548 278 372 1.41E-12 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HVS_RS06955 827f73191ae7dac1d71e1c35402f09de 407 Pfam PF13534 4Fe-4S dicluster domain 295 364 5.8E-10 T 29-03-2018 HVS_RS09980 82a39fd6235d3b93345c9551e863b4c7 182 Pfam PF05137 Fimbrial assembly protein (PilN) 110 157 5.1E-5 T 29-03-2018 IPR007813 Fimbrial assembly PilN HVS_RS14465 02661cb34d41c49f72a36807488a5900 281 ProSitePatterns PS00801 Transketolase signature 1. 17 37 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS14465 02661cb34d41c49f72a36807488a5900 281 Gene3D G3DSA:3.40.50.970 2 276 7.2E-87 T 29-03-2018 HVS_RS14465 02661cb34d41c49f72a36807488a5900 281 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 263 2.9E-70 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 HVS_RS14465 02661cb34d41c49f72a36807488a5900 281 SUPERFAMILY SSF52518 6 272 6.37E-98 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 SUPERFAMILY SSF50249 7 84 2.4E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 2.0E-12 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 2.0E-12 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 2.0E-12 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 8.0E-31 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 25.547 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.0E-36 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 Pfam PF00366 Ribosomal protein S17 12 79 2.8E-33 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15095 778ec9025e3c95d5cf6e83f919460a9b 85 Gene3D G3DSA:2.40.50.140 7 84 4.6E-32 T 29-03-2018 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 761 779 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Gene3D G3DSA:1.20.80.30 118 197 2.7E-36 T 29-03-2018 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Gene3D G3DSA:3.20.20.60 536 874 2.9E-125 T 29-03-2018 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Gene3D G3DSA:1.10.189.10 341 389 4.9E-21 T 29-03-2018 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 519 869 5.3E-96 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Pfam PF00391 PEP-utilising enzyme, mobile domain 420 504 9.6E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Gene3D G3DSA:3.30.1490.20 2 117 3.3E-36 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 871 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 SUPERFAMILY SSF52009 389 513 5.49E-34 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 SUPERFAMILY SSF56059 1 378 5.06E-154 T 29-03-2018 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 289 4.5E-49 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 302 355 8.8E-11 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Gene3D G3DSA:3.50.30.10 391 535 3.0E-42 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 PIRSF PIRSF000853 1 877 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 SUPERFAMILY SSF51621 512 869 3.14E-135 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HVS_RS11055 bdec126c489a3891ecbf3550cdf2113a 877 Gene3D G3DSA:3.30.470.20 243 340 6.7E-24 T 29-03-2018 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 SUPERFAMILY SSF51011 630 733 1.22E-34 T 29-03-2018 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 112 731 3.5E-304 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 26 103 3.4E-5 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 127 210 4.7E-23 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 634 732 1.6E-21 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 PIRSF PIRSF000463 8 739 0.0 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 SMART SM00642 254 616 6.3E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 104 733 46.096 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Gene3D G3DSA:2.60.40.1180 644 733 4.3E-35 T 29-03-2018 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 SUPERFAMILY SSF81296 18 118 2.8E-18 T 29-03-2018 IPR014756 Immunoglobulin E-set HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 SUPERFAMILY SSF51445 182 622 3.5E-121 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Gene3D G3DSA:3.20.20.80 247 643 2.7E-80 T 29-03-2018 HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Gene3D G3DSA:2.60.40.10 2 107 1.1E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Gene3D G3DSA:2.60.40.10 119 246 1.6E-35 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01170 65a11766f56c536f6b0a0e62915ba7c1 739 Pfam PF00128 Alpha amylase, catalytic domain 281 353 4.1E-12 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HVS_RS14230 1366ff39db68a3869dbd9cf8b740c81c 274 Pfam PF00188 Cysteine-rich secretory protein family 156 271 5.7E-17 T 29-03-2018 IPR014044 CAP domain HVS_RS14230 1366ff39db68a3869dbd9cf8b740c81c 274 Gene3D G3DSA:3.40.33.10 146 271 3.9E-17 T 29-03-2018 IPR014044 CAP domain HVS_RS14230 1366ff39db68a3869dbd9cf8b740c81c 274 Gene3D G3DSA:2.40.50.110 21 103 6.6E-11 T 29-03-2018 HVS_RS14230 1366ff39db68a3869dbd9cf8b740c81c 274 SUPERFAMILY SSF55797 150 271 5.58E-21 T 29-03-2018 IPR014044 CAP domain HVS_RS14230 1366ff39db68a3869dbd9cf8b740c81c 274 Pfam PF08239 Bacterial SH3 domain 48 96 5.6E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type HVS_RS14230 1366ff39db68a3869dbd9cf8b740c81c 274 SMART SM00287 40 99 3.0E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Pfam PF00404 Dockerin type I repeat 402 421 8.6E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Pfam PF00404 Dockerin type I repeat 435 455 9.0E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 714 724 - T 29-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 115 125 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 SUPERFAMILY SSF49785 256 382 6.12E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Pfam PF03422 Carbohydrate binding module (family 6) 263 382 6.5E-31 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Gene3D G3DSA:2.60.120.260 252 383 1.9E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Gene3D G3DSA:3.20.20.80 476 806 2.1E-73 T 29-03-2018 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Pfam PF00457 Glycosyl hydrolases family 11 37 218 1.4E-66 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 SMART SM00633 529 801 2.3E-149 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Pfam PF00331 Glycosyl hydrolase family 10 484 800 4.1E-119 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Gene3D G3DSA:1.10.1330.10 397 466 1.3E-5 T 29-03-2018 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 SMART SM00606 255 382 1.6E-47 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 PRINTS PR00134 Glycosyl hydrolase family 10 signature 560 572 1.3E-17 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 PRINTS PR00134 Glycosyl hydrolase family 10 signature 649 660 1.3E-17 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 PRINTS PR00134 Glycosyl hydrolase family 10 signature 604 615 1.3E-17 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 PRINTS PR00134 Glycosyl hydrolase family 10 signature 678 690 1.3E-17 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 Gene3D G3DSA:2.60.120.180 21 226 2.9E-87 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 SUPERFAMILY SSF49899 27 227 2.83E-83 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 435 454 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 SUPERFAMILY SSF51445 478 803 2.49E-114 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS00465 d3b07c59351565aa10b4a408d79b9642 807 SUPERFAMILY SSF63446 397 465 1.57E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 Gene3D G3DSA:1.10.150.300 108 198 2.5E-30 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 103 5.8E-38 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 5.8E-38 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 68 83 5.8E-38 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 5.8E-38 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 364 3.3E-160 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 PIRSF PIRSF006641 1 364 9.2E-161 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 SUPERFAMILY SSF52540 1 302 1.17E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 Gene3D G3DSA:3.10.20.30 264 363 5.5E-46 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 SUPERFAMILY SSF81271 280 361 5.01E-35 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 2.0E-39 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 Pfam PF01926 50S ribosome-binding GTPase 3 124 1.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 364 45.249 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 HVS_RS08725 a36a07f9252872496652cb8c42445ae5 364 Gene3D G3DSA:3.40.50.300 1 78 3.4E-8 T 29-03-2018 HVS_RS07780 7aa0dd8eadbf819872e2aa41f3f3065f 352 Pfam PF09084 NMT1/THI5 like 65 279 3.3E-77 T 29-03-2018 IPR015168 SsuA/THI5-like HVS_RS07780 7aa0dd8eadbf819872e2aa41f3f3065f 352 SUPERFAMILY SSF53850 57 341 4.22E-48 T 29-03-2018 HVS_RS07780 7aa0dd8eadbf819872e2aa41f3f3065f 352 Gene3D G3DSA:3.40.190.10 53 156 9.4E-16 T 29-03-2018 HVS_RS07780 7aa0dd8eadbf819872e2aa41f3f3065f 352 Gene3D G3DSA:3.40.190.10 159 351 8.0E-32 T 29-03-2018 HVS_RS02120 c38cfbb08e2842e4c2a50bd582497b1c 293 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 54 276 5.8E-86 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 HVS_RS02120 c38cfbb08e2842e4c2a50bd582497b1c 293 Hamap MF_02040 Iron-sulfur cluster carrier protein. 49 292 33.663 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein HVS_RS02120 c38cfbb08e2842e4c2a50bd582497b1c 293 Gene3D G3DSA:3.40.50.300 37 276 4.7E-56 T 29-03-2018 HVS_RS02120 c38cfbb08e2842e4c2a50bd582497b1c 293 SUPERFAMILY SSF52540 47 276 2.58E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 52 227 2.9E-52 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 85 102 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 Gene3D G3DSA:2.40.100.10 28 229 2.7E-71 T 29-03-2018 IPR029000 Cyclophilin-like domain HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 132 147 3.4E-18 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 90 102 3.4E-18 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 64 79 3.4E-18 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 PIRSF PIRSF001467 153 231 6.1E-12 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 PIRSF PIRSF001467 45 162 6.8E-43 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 SUPERFAMILY SSF50891 180 228 1.75E-62 T 29-03-2018 IPR029000 Cyclophilin-like domain HVS_RS15695 f7e92e895b936ecc151b0ad3bd6fbb74 232 SUPERFAMILY SSF50891 48 151 1.75E-62 T 29-03-2018 IPR029000 Cyclophilin-like domain HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Pfam PF04545 Sigma-70, region 4 191 238 7.4E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Pfam PF04542 Sigma-70 region 2 27 93 3.0E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 20 239 1.2E-76 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Gene3D G3DSA:1.10.1270.10 153 243 7.3E-15 T 29-03-2018 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Gene3D G3DSA:1.10.10.10 94 131 5.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 SUPERFAMILY SSF88946 6 93 1.73E-29 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 239 2.3E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 PRINTS PR00046 Major sigma-70 factor signature 49 62 6.1E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 PRINTS PR00046 Major sigma-70 factor signature 194 206 6.1E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 PRINTS PR00046 Major sigma-70 factor signature 211 226 6.1E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 PRINTS PR00046 Major sigma-70 factor signature 226 237 6.1E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Gene3D G3DSA:1.10.601.10 2 93 3.0E-24 T 29-03-2018 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 SUPERFAMILY SSF88659 98 172 2.92E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Pfam PF04539 Sigma-70 region 3 104 169 2.1E-12 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 Gene3D G3DSA:1.10.10.60 132 148 0.2 T 29-03-2018 HVS_RS15175 a192e34a64610b0fed394b13957f7618 243 SUPERFAMILY SSF88659 159 242 2.62E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS07620 0159358e9529377aa3fec35977056521 222 Gene3D G3DSA:3.40.50.300 1 192 6.7E-12 T 29-03-2018 HVS_RS07620 0159358e9529377aa3fec35977056521 222 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 159 1.1E-5 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain HVS_RS07620 0159358e9529377aa3fec35977056521 222 SUPERFAMILY SSF52540 4 189 4.81E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05310 dd675e30196131099b4c24511d803509 321 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 217 318 4.5E-8 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF HVS_RS05310 dd675e30196131099b4c24511d803509 321 Pfam PF17115 N-terminal domain of toast_rack, DUF2154 125 211 8.6E-5 T 29-03-2018 IPR031346 Uncharacterised protein DUF2154, N-terminal HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 ProSitePatterns PS01108 Ribosomal protein L24 signature. 10 27 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 5 100 19.599 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 5 106 4.8E-36 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 SMART SM00739 6 33 3.7E-5 T 29-03-2018 IPR005824 KOW HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 106 5.9E-27 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 Gene3D G3DSA:2.30.30.30 1 95 1.0E-32 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 Pfam PF00467 KOW motif 9 40 8.2E-7 T 29-03-2018 IPR005824 KOW HVS_RS15085 1110d992a964d0a9a32468ce7978f111 114 SUPERFAMILY SSF50104 3 105 2.18E-34 T 29-03-2018 IPR008991 Translation protein SH3-like domain HVS_RS14095 c35ba7953f275c0223b93b063fe5697d 273 Pfam PF01882 Protein of unknown function DUF58 37 118 9.0E-23 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS14095 c35ba7953f275c0223b93b063fe5697d 273 Gene3D G3DSA:3.40.50.410 49 255 2.4E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14095 c35ba7953f275c0223b93b063fe5697d 273 SUPERFAMILY SSF53300 73 210 2.02E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 SMART SM01329 10 395 6.7E-114 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 392 1.5E-65 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 400 7.2E-169 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 Gene3D G3DSA:3.40.718.10 2 402 2.7E-119 T 29-03-2018 HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 PIRSF PIRSF000108 1 402 1.6E-204 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 HVS_RS05165 f2494f0e1c43b7d2073097cd187565b0 402 SUPERFAMILY SSF53659 2 400 4.61E-136 T 29-03-2018 HVS_RS15250 ee664cafb2e5c3305d02f224ea5fc8bd 238 SUPERFAMILY SSF51366 1 234 3.3E-76 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS15250 ee664cafb2e5c3305d02f224ea5fc8bd 238 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 232 2.9E-91 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 HVS_RS15250 ee664cafb2e5c3305d02f224ea5fc8bd 238 Pfam PF00977 Histidine biosynthesis protein 3 227 6.6E-86 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 HVS_RS15250 ee664cafb2e5c3305d02f224ea5fc8bd 238 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 38.534 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 HVS_RS15250 ee664cafb2e5c3305d02f224ea5fc8bd 238 Gene3D G3DSA:3.20.20.70 1 238 7.8E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS02860 441ce392793c245bc4e0a053ad4b3090 319 Pfam PF13732 Domain of unknown function (DUF4162) 216 304 4.6E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 HVS_RS02860 441ce392793c245bc4e0a053ad4b3090 319 Pfam PF00005 ABC transporter 20 162 1.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS02860 441ce392793c245bc4e0a053ad4b3090 319 Gene3D G3DSA:3.40.50.300 1 271 2.7E-66 T 29-03-2018 HVS_RS02860 441ce392793c245bc4e0a053ad4b3090 319 SMART SM00382 28 214 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02860 441ce392793c245bc4e0a053ad4b3090 319 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS02860 441ce392793c245bc4e0a053ad4b3090 319 SUPERFAMILY SSF52540 4 224 5.76E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00400 6142a5cfe6d5fb21d94fe92b2ccb0834 159 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 21 153 4.2E-44 T 29-03-2018 IPR006286 Peptidase C56, PfpI HVS_RS00400 6142a5cfe6d5fb21d94fe92b2ccb0834 159 Pfam PF01965 DJ-1/PfpI family 18 151 5.9E-42 T 29-03-2018 IPR002818 DJ-1/PfpI HVS_RS00400 6142a5cfe6d5fb21d94fe92b2ccb0834 159 Gene3D G3DSA:3.40.50.880 7 159 2.2E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS00400 6142a5cfe6d5fb21d94fe92b2ccb0834 159 SUPERFAMILY SSF52317 8 154 5.3E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 2.4E-5 T 29-03-2018 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 369 376 2.4E-5 T 29-03-2018 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 Pfam PF13932 GidA associated domain 405 619 1.4E-80 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 372 395 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 SUPERFAMILY SSF51905 7 67 1.05E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 SUPERFAMILY SSF51905 98 265 1.05E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 277 291 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 624 8.9E-276 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 627 42.448 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 Pfam PF01134 Glucose inhibited division protein A 9 403 4.1E-165 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 SMART SM01228 549 620 5.2E-43 T 29-03-2018 HVS_RS16175 f9934754d92d8475a7177dae0dcf8ff9 634 Gene3D G3DSA:3.50.50.60 6 269 1.6E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 Gene3D G3DSA:3.40.50.620 1 216 8.4E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 4 358 5.9E-113 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 SUPERFAMILY SSF52402 2 250 5.07E-58 T 29-03-2018 HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 Gene3D G3DSA:2.40.30.10 281 359 2.3E-23 T 29-03-2018 HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 359 41.473 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 Pfam PF03054 tRNA methyl transferase 4 358 9.4E-124 T 29-03-2018 HVS_RS08040 9d30e8362e81c7a351dd18debeec51aa 359 Gene3D G3DSA:2.30.30.280 221 280 7.5E-20 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Gene3D G3DSA:1.10.1780.10 1 153 2.1E-31 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 860 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Gene3D G3DSA:1.10.8.60 345 550 9.0E-44 T 29-03-2018 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 1.8E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 1.8E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 1.8E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 1.8E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 318 3.1E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 68 2.1E-5 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 3.1E-9 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 SUPERFAMILY SSF52540 161 548 6.74E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Gene3D G3DSA:3.40.50.300 159 344 1.4E-23 T 29-03-2018 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Gene3D G3DSA:1.10.8.60 771 862 5.6E-24 T 29-03-2018 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 765 1.3E-54 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Gene3D G3DSA:3.40.50.300 555 770 1.0E-53 T 29-03-2018 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 SMART SM00382 200 344 2.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 SMART SM00382 600 753 1.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 SUPERFAMILY SSF52540 549 857 3.77E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 SMART SM01086 771 860 2.1E-31 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 SUPERFAMILY SSF81923 4 157 3.92E-37 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS04215 3f3a6ebd2e2a97d3d352423d2493b6a7 862 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 771 851 5.8E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS04380 2ee1344d11d70ea16418b80e83519896 336 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 186 1.2E-19 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS04380 2ee1344d11d70ea16418b80e83519896 336 Gene3D G3DSA:3.40.47.10 1 162 2.4E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS04380 2ee1344d11d70ea16418b80e83519896 336 SUPERFAMILY SSF53901 5 334 1.46E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS04380 2ee1344d11d70ea16418b80e83519896 336 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 249 335 8.9E-31 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS04380 2ee1344d11d70ea16418b80e83519896 336 Gene3D G3DSA:3.40.47.10 163 336 4.1E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 PIRSF PIRSF005572 3 383 3.2E-138 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 195 214 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 Pfam PF00266 Aminotransferase class-V 6 368 8.8E-88 T 29-03-2018 IPR000192 Aminotransferase class V domain HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 SUPERFAMILY SSF53383 5 377 1.04E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 6 385 3.2E-185 T 29-03-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 Gene3D G3DSA:3.90.1150.10 266 383 1.3E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 Gene3D G3DSA:3.40.640.10 14 258 5.1E-63 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS08050 5f6bf28ccfaad09f2ac6dd27e8851a3f 396 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 394 54.497 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 HVS_RS13065 24a4a893f8867ebb558e41d20a35e9ce 520 SUPERFAMILY SSF144091 179 360 2.62E-46 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS13065 24a4a893f8867ebb558e41d20a35e9ce 520 Gene3D G3DSA:1.10.287.1110 490 506 1.1E-4 T 29-03-2018 HVS_RS13065 24a4a893f8867ebb558e41d20a35e9ce 520 Gene3D G3DSA:1.25.40.10 393 489 1.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13065 24a4a893f8867ebb558e41d20a35e9ce 520 Pfam PF01694 Rhomboid family 226 360 2.9E-36 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS13065 24a4a893f8867ebb558e41d20a35e9ce 520 SUPERFAMILY SSF48452 412 506 3.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS13065 24a4a893f8867ebb558e41d20a35e9ce 520 Gene3D G3DSA:1.20.1540.10 178 362 5.8E-43 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 Gene3D G3DSA:1.10.1200.10 1 74 1.3E-26 T 29-03-2018 HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 Pfam PF00550 Phosphopantetheine attachment site 3 70 5.5E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 Hamap MF_01217 Acyl carrier protein [acpP]. 1 74 21.18 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 73 5.4E-35 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 ProSitePatterns PS00012 Phosphopantetheine attachment site. 29 44 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 73 2.0E-12 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 SUPERFAMILY SSF47336 1 73 1.03E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS08815 7a604c459e52c039dc3882c33e916945 74 SMART SM00823 Phosphopantetheine attachment site 2 60 0.0089 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 HVS_RS12525 4f41f0d0c2b64264ac30bcda0759df70 335 Gene3D G3DSA:1.10.10.60 277 329 1.1E-5 T 29-03-2018 HVS_RS12525 4f41f0d0c2b64264ac30bcda0759df70 335 Pfam PF04754 Putative transposase, YhgA-like 12 103 2.0E-4 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS12165 e10fa72983bcdb857f008b61474660bf 416 SUPERFAMILY SSF58104 145 414 9.68E-62 T 29-03-2018 HVS_RS12165 e10fa72983bcdb857f008b61474660bf 416 SMART SM00283 140 415 2.7E-58 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS12165 e10fa72983bcdb857f008b61474660bf 416 Gene3D G3DSA:1.10.287.950 60 172 5.8E-7 T 29-03-2018 HVS_RS12165 e10fa72983bcdb857f008b61474660bf 416 Gene3D G3DSA:1.10.287.950 173 416 1.1E-48 T 29-03-2018 HVS_RS12165 e10fa72983bcdb857f008b61474660bf 416 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 208 368 3.2E-40 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS12165 e10fa72983bcdb857f008b61474660bf 416 SUPERFAMILY SSF58104 64 174 3.66E-5 T 29-03-2018 HVS_RS06160 d075deb8ca2023e0ac5e157f97474524 164 SUPERFAMILY SSF48317 32 163 7.59E-29 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS06160 d075deb8ca2023e0ac5e157f97474524 164 Pfam PF01569 PAP2 superfamily 56 163 9.4E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS06160 d075deb8ca2023e0ac5e157f97474524 164 SMART SM00014 56 163 2.0E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS06160 d075deb8ca2023e0ac5e157f97474524 164 Gene3D G3DSA:1.20.144.10 25 163 1.3E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS05460 bb38786ae984600272624646bcab6652 426 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 387 49.459 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 HVS_RS05460 bb38786ae984600272624646bcab6652 426 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 360 7.4E-151 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 HVS_RS05460 bb38786ae984600272624646bcab6652 426 SUPERFAMILY SSF51161 227 404 4.58E-30 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS05460 bb38786ae984600272624646bcab6652 426 SUPERFAMILY SSF53448 3 263 2.82E-83 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05460 bb38786ae984600272624646bcab6652 426 SUPERFAMILY SSF53448 307 323 2.82E-83 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05460 bb38786ae984600272624646bcab6652 426 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 HVS_RS05460 bb38786ae984600272624646bcab6652 426 Gene3D G3DSA:2.160.10.10 260 422 4.0E-19 T 29-03-2018 HVS_RS05460 bb38786ae984600272624646bcab6652 426 Pfam PF00483 Nucleotidyl transferase 8 259 7.0E-67 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS05460 bb38786ae984600272624646bcab6652 426 Gene3D G3DSA:3.90.550.10 1 259 4.3E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS05460 bb38786ae984600272624646bcab6652 426 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 333 360 0.0021 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS05460 bb38786ae984600272624646bcab6652 426 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 HVS_RS05460 bb38786ae984600272624646bcab6652 426 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 1.1E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 SUPERFAMILY SSF50104 1 113 5.82E-47 T 29-03-2018 IPR008991 Translation protein SH3-like domain HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 Pfam PF01245 Ribosomal protein L19 3 111 4.7E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 PRINTS PR00061 Ribosomal protein L19 signature 87 112 3.2E-39 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 PRINTS PR00061 Ribosomal protein L19 signature 33 62 3.2E-39 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 PRINTS PR00061 Ribosomal protein L19 signature 3 32 3.2E-39 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 32.627 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09240 b2bd98ae6400a4268e933ca2977d661a 121 PIRSF PIRSF002191 1 121 7.1E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15675 47efaea0e1ef9a0eb8ae00327eab00ab 621 Gene3D G3DSA:3.40.720.10 247 550 1.3E-45 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS15675 47efaea0e1ef9a0eb8ae00327eab00ab 621 Pfam PF00884 Sulfatase 255 542 7.0E-37 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 HVS_RS15675 47efaea0e1ef9a0eb8ae00327eab00ab 621 PIRSF PIRSF005091 4 621 1.5E-146 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like HVS_RS15675 47efaea0e1ef9a0eb8ae00327eab00ab 621 SUPERFAMILY SSF53649 253 578 8.01E-60 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 Gene3D G3DSA:3.30.70.260 308 387 2.9E-11 T 29-03-2018 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 Gene3D G3DSA:3.40.50.720 123 164 3.7E-4 T 29-03-2018 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 140 167 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 306 6.9E-22 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 SUPERFAMILY SSF51735 83 274 4.13E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 93 274 1.3E-40 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 Gene3D G3DSA:3.40.50.720 165 306 4.0E-32 T 29-03-2018 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 SUPERFAMILY SSF52283 20 105 6.8E-23 T 29-03-2018 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 SUPERFAMILY SSF55021 315 386 5.83E-13 T 29-03-2018 HVS_RS02415 7aa7b2d81cf6ee3ac1b204612063eeeb 396 Gene3D G3DSA:3.40.50.720 2 122 3.1E-22 T 29-03-2018 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 SUPERFAMILY SSF103190 97 236 1.1E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 Gene3D G3DSA:3.30.450.20 195 332 3.2E-17 T 29-03-2018 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 509 660 1.0E-25 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 Pfam PF00672 HAMP domain 363 410 7.8E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 Pfam PF02743 Cache domain 90 326 5.9E-19 T 29-03-2018 IPR033479 Double Cache domain 1 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 Gene3D G3DSA:1.10.287.950 390 470 4.4E-5 T 29-03-2018 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 SMART SM00283 444 719 6.9E-27 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 SMART SM00304 363 415 1.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 SUPERFAMILY SSF58104 450 718 1.57E-54 T 29-03-2018 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 SUPERFAMILY SSF58104 383 417 1.57E-54 T 29-03-2018 HVS_RS13900 2a9d709fd1b9ffd615bf74daa19f8fac 724 Gene3D G3DSA:1.10.287.950 471 723 1.3E-32 T 29-03-2018 HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 40.408 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 453 2.0E-174 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Pfam PF00483 Nucleotidyl transferase 6 219 4.5E-21 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 SUPERFAMILY SSF53448 4 307 1.33E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 300 7.1E-7 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 1.4E-6 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 322 352 9.7E-5 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Gene3D G3DSA:2.160.10.10 316 447 1.2E-33 T 29-03-2018 HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Gene3D G3DSA:3.90.550.10 1 245 4.9E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 Gene3D G3DSA:2.160.10.10 246 315 4.6E-18 T 29-03-2018 HVS_RS00525 df0a67b4d79916d71c2b4f96fc0b3c1b 459 SUPERFAMILY SSF51161 255 447 1.77E-49 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 Gene3D G3DSA:1.10.268.10 337 479 1.1E-34 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 SUPERFAMILY SSF56719 4 481 5.49E-125 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 SUPERFAMILY SSF101904 493 694 3.14E-38 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 464 9.3E-127 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 SMART SM00434 9 457 3.0E-135 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 Gene3D G3DSA:2.120.10.90 490 709 2.4E-37 T 29-03-2018 HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 Gene3D G3DSA:3.30.1360.40 232 325 1.4E-24 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 HVS_RS05225 b44f57fbb89071957251f455dab47a0a 727 Gene3D G3DSA:3.90.199.10 32 210 1.4E-56 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 SUPERFAMILY SSF54768 122 234 6.44E-24 T 29-03-2018 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 SMART SM00535 26 161 1.9E-47 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 Pfam PF00035 Double-stranded RNA binding motif 168 234 6.7E-16 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 SMART SM00358 168 235 2.7E-20 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 Gene3D G3DSA:3.30.160.20 153 231 2.5E-21 T 29-03-2018 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 Gene3D G3DSA:1.10.1520.10 1 152 1.9E-44 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 14 233 8.5E-78 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 Pfam PF14622 Ribonuclease-III-like 28 151 5.2E-40 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 Hamap MF_00104 Ribonuclease 3 [rnc]. 14 231 29.971 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 HVS_RS08805 ac96b6526ebf3440573549fa02edce02 238 SUPERFAMILY SSF69065 10 170 1.38E-48 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS01380 2d1b0aaf485b048a96c7be4be872d11e 489 SUPERFAMILY SSF64518 324 482 2.22E-15 T 29-03-2018 HVS_RS01380 2d1b0aaf485b048a96c7be4be872d11e 489 SUPERFAMILY SSF64518 149 291 2.22E-15 T 29-03-2018 HVS_RS01380 2d1b0aaf485b048a96c7be4be872d11e 489 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 7.0E-5 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS01380 2d1b0aaf485b048a96c7be4be872d11e 489 PRINTS PR01005 Flagellar hook-associated protein signature 162 186 7.0E-5 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS01380 2d1b0aaf485b048a96c7be4be872d11e 489 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 482 5.0E-103 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 HVS_RS01380 2d1b0aaf485b048a96c7be4be872d11e 489 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 432 482 8.1E-11 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HVS_RS06250 bb20e1d598116d649e1d926408789b08 320 Gene3D G3DSA:3.30.420.40 1 123 3.3E-26 T 29-03-2018 HVS_RS06250 bb20e1d598116d649e1d926408789b08 320 ProSitePatterns PS01125 ROK family signature. 138 165 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 HVS_RS06250 bb20e1d598116d649e1d926408789b08 320 Gene3D G3DSA:3.30.420.40 124 319 7.0E-54 T 29-03-2018 HVS_RS06250 bb20e1d598116d649e1d926408789b08 320 Pfam PF00480 ROK family 5 318 1.8E-68 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 HVS_RS06250 bb20e1d598116d649e1d926408789b08 320 SUPERFAMILY SSF53067 4 318 9.73E-67 T 29-03-2018 HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 Gene3D G3DSA:1.20.272.10 208 327 8.3E-19 T 29-03-2018 HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 14 201 7.6E-57 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 SUPERFAMILY SSF52540 3 205 1.05E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 220 325 2.6E-7 T 29-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 Gene3D G3DSA:3.40.50.300 10 154 4.5E-32 T 29-03-2018 HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 Gene3D G3DSA:1.10.8.60 155 207 5.3E-5 T 29-03-2018 HVS_RS14635 38e1e6cce6b9226029c967bb10e07456 329 Pfam PF13177 DNA polymerase III, delta subunit 8 166 1.7E-53 T 29-03-2018 HVS_RS10575 1b3ded9919d2379b1c5723f34f624bf0 169 Pfam PF00186 Dihydrofolate reductase 2 160 1.0E-42 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 HVS_RS10575 1b3ded9919d2379b1c5723f34f624bf0 169 Gene3D G3DSA:3.40.430.10 1 165 1.4E-42 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 HVS_RS10575 1b3ded9919d2379b1c5723f34f624bf0 169 PRINTS PR00070 Dihydrofolate reductase signature 94 108 2.7E-11 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 HVS_RS10575 1b3ded9919d2379b1c5723f34f624bf0 169 PRINTS PR00070 Dihydrofolate reductase signature 26 34 2.7E-11 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 HVS_RS10575 1b3ded9919d2379b1c5723f34f624bf0 169 PRINTS PR00070 Dihydrofolate reductase signature 39 50 2.7E-11 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 HVS_RS10575 1b3ded9919d2379b1c5723f34f624bf0 169 SUPERFAMILY SSF53597 2 162 5.37E-46 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Gene3D G3DSA:3.30.56.50 11 53 8.6E-14 T 29-03-2018 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Gene3D G3DSA:3.30.56.50 431 472 5.6E-12 T 29-03-2018 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Gene3D G3DSA:3.40.50.10050 809 885 3.9E-29 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 SUPERFAMILY SSF52156 786 913 6.54E-39 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 10 1004 17.59 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 SUPERFAMILY SSF50447 678 761 1.04E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Pfam PF00009 Elongation factor Tu GTP binding domain 511 667 2.2E-34 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 429 478 4.1E-17 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 10 59 3.9E-14 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal HVS_RS10520 602c9faad01518f885840977dc34062d 1004 SUPERFAMILY SSF52540 497 679 7.34E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10520 602c9faad01518f885840977dc34062d 1004 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 509 665 1.2E-33 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Gene3D G3DSA:2.40.30.10 907 1004 2.8E-29 T 29-03-2018 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 ProSitePatterns PS01176 Initiation factor 2 signature. 957 979 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Gene3D G3DSA:2.40.30.10 687 808 2.8E-33 T 29-03-2018 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 SUPERFAMILY SSF50447 907 1003 1.73E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Pfam PF11987 Translation-initiation factor 2 792 896 7.1E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 424 1003 3.6E-257 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 HVS_RS10520 602c9faad01518f885840977dc34062d 1004 Gene3D G3DSA:3.40.50.300 502 686 3.4E-42 T 29-03-2018 HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 Pfam PF00271 Helicase conserved C-terminal domain 601 685 5.7E-6 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 SMART SM00490 600 686 1.9E-8 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 SUPERFAMILY SSF52540 536 698 2.09E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 Pfam PF00270 DEAD/DEAH box helicase 290 455 4.9E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 SMART SM00487 283 483 1.0E-19 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 Gene3D G3DSA:3.40.50.300 523 757 1.8E-15 T 29-03-2018 HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 SUPERFAMILY SSF52540 216 466 2.74E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 Pfam PF08797 HIRAN domain 1052 1119 9.4E-7 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 HVS_RS02850 5ed00922d7d8b8261f0193487a287176 1142 Gene3D G3DSA:3.40.50.300 268 474 1.8E-28 T 29-03-2018 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 319 2.3E-119 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 SUPERFAMILY SSF52374 2 312 1.39E-118 T 29-03-2018 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Gene3D G3DSA:1.10.10.350 382 484 4.0E-24 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 478 5.2E-180 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 481 33.946 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Gene3D G3DSA:1.10.1160.10 245 328 2.2E-37 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Gene3D G3DSA:1.10.8.70 330 379 1.2E-5 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 216 9.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 47 9.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 5 17 9.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 192 202 9.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 30 9.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Gene3D G3DSA:3.40.50.620 126 244 9.6E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 8 19 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 Gene3D G3DSA:3.40.50.620 2 125 2.4E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS15725 7ef1646bd2a3cd9a3e539e1bf22656d2 485 SUPERFAMILY SSF48163 293 478 7.32E-45 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 HVS_RS02750 ad2f13577978b172aebe9195a01c5f36 232 Pfam PF04607 Region found in RelA / SpoT proteins 36 157 4.3E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 HVS_RS02750 ad2f13577978b172aebe9195a01c5f36 232 SMART SM00954 36 159 2.6E-46 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 HVS_RS02750 ad2f13577978b172aebe9195a01c5f36 232 Gene3D G3DSA:3.30.460.10 1 140 1.5E-37 T 29-03-2018 HVS_RS02750 ad2f13577978b172aebe9195a01c5f36 232 SUPERFAMILY SSF81301 2 189 5.72E-55 T 29-03-2018 HVS_RS02750 ad2f13577978b172aebe9195a01c5f36 232 Gene3D G3DSA:1.10.287.860 142 190 3.3E-20 T 29-03-2018 HVS_RS15950 0d806d29c63ebe7caf5b9bf60d022dbb 302 Pfam PF09648 YycH protein 35 287 2.4E-17 T 29-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 SUPERFAMILY SSF56601 4 282 4.83E-58 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 SMART SM00936 282 374 1.4E-14 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 22 261 2.3E-49 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 3.4E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 134 147 3.4E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 3.4E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 Gene3D G3DSA:2.60.410.10 282 374 1.7E-15 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 282 374 8.1E-13 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 SUPERFAMILY SSF69189 282 374 5.3E-12 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS06275 12187b970c678fd7e8a414b7ff6ad115 428 Gene3D G3DSA:3.40.710.10 15 281 8.0E-36 T 29-03-2018 HVS_RS04425 59494f5ef091ac64428b571b33dc9e0d 71 SUPERFAMILY SSF47336 2 71 8.77E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS04425 59494f5ef091ac64428b571b33dc9e0d 71 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 69 0.008 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 HVS_RS04425 59494f5ef091ac64428b571b33dc9e0d 71 Pfam PF00550 Phosphopantetheine attachment site 2 69 2.1E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS04425 59494f5ef091ac64428b571b33dc9e0d 71 Gene3D G3DSA:1.10.1200.10 1 71 4.0E-14 T 29-03-2018 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 2.7E-63 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 2.0E-13 T 29-03-2018 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 SUPERFAMILY SSF54747 3 72 2.75E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 30.326 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 140 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 SUPERFAMILY SSF46906 67 140 2.62E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.9E-21 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 SMART SM00649 9 140 1.3E-81 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 Gene3D G3DSA:1.10.10.250 72 140 5.0E-22 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 Gene3D G3DSA:3.30.1550.10 3 71 4.9E-36 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal HVS_RS12975 a6631db7531ae68b30e40b6c2dada0c5 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.1E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal HVS_RS01105 f133e2866d97aca43e6937d947bab3b5 286 Gene3D G3DSA:3.30.457.10 66 127 3.0E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01105 f133e2866d97aca43e6937d947bab3b5 286 Gene3D G3DSA:3.30.457.10 20 65 4.4E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01105 f133e2866d97aca43e6937d947bab3b5 286 Gene3D G3DSA:3.30.457.10 128 251 1.6E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01105 f133e2866d97aca43e6937d947bab3b5 286 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 1.1E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01105 f133e2866d97aca43e6937d947bab3b5 286 SUPERFAMILY SSF55383 56 139 1.06E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:3.30.457.10 23 76 1.7E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:3.30.457.10 163 231 1.8E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:3.30.457.10 77 162 2.2E-11 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Pfam PF01841 Transglutaminase-like superfamily 660 771 1.0E-7 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 SUPERFAMILY SSF54001 610 790 1.16E-20 T 29-03-2018 HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:2.60.40.10 327 420 0.0022 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 SUPERFAMILY SSF55383 146 174 4.84E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Pfam PF07833 Copper amine oxidase N-terminal domain 63 93 5.5E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 Pfam PF07833 Copper amine oxidase N-terminal domain 150 183 3.1E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06090 da3b189ce2dbb6c8fb24948e4ebeed14 892 SMART SM00460 718 774 7.2E-9 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:3.30.457.10 23 76 1.7E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:3.30.457.10 163 231 1.8E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:3.30.457.10 77 162 2.2E-11 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Pfam PF01841 Transglutaminase-like superfamily 660 771 1.0E-7 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 SUPERFAMILY SSF54001 610 790 1.16E-20 T 29-03-2018 HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Gene3D G3DSA:2.60.40.10 327 420 0.0022 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 SUPERFAMILY SSF55383 146 174 4.84E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Pfam PF07833 Copper amine oxidase N-terminal domain 63 93 5.5E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 Pfam PF07833 Copper amine oxidase N-terminal domain 150 183 3.1E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14735 da3b189ce2dbb6c8fb24948e4ebeed14 892 SMART SM00460 718 774 7.2E-9 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 Gene3D G3DSA:3.30.250.10 270 327 1.8E-27 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 ProSitePatterns PS00321 recA signature. 214 222 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 SUPERFAMILY SSF52540 6 268 1.43E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 PRINTS PR00142 RecA protein signature 211 239 3.1E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 PRINTS PR00142 RecA protein signature 94 123 3.1E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 PRINTS PR00142 RecA protein signature 244 273 3.1E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 PRINTS PR00142 RecA protein signature 128 157 3.1E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 PRINTS PR00142 RecA protein signature 166 195 3.1E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 PRINTS PR00142 RecA protein signature 298 315 3.1E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 Pfam PF00154 recA bacterial DNA recombination protein 8 269 1.2E-145 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 Hamap MF_00268 Protein RecA [recA]. 6 330 53.561 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 SMART SM00382 58 229 8.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 Gene3D G3DSA:3.40.50.300 27 269 8.9E-50 T 29-03-2018 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 8.2E-178 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HVS_RS07515 2481a684f8bc75def00dda0ce4156e3c 349 SUPERFAMILY SSF54752 269 326 6.28E-23 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 265 284 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 112 135 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 71 91 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 306 328 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 144 169 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 170 193 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 361 379 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PRINTS PR00303 Preprotein translocase SecY subunit signature 394 412 5.5E-86 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 420 2.5E-121 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 ProSitePatterns PS00756 Protein secY signature 2. 163 180 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 PIRSF PIRSF004557 2 426 7.5E-120 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 Gene3D G3DSA:1.10.3370.10 4 426 2.6E-154 T 29-03-2018 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 Pfam PF00344 SecY translocase 72 409 8.9E-115 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 SUPERFAMILY SSF103491 4 416 1.31E-118 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS15040 f87f00d3fc7a03d356a3bf69dc4b33fa 426 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 425 28.816 T 29-03-2018 IPR026593 Protein translocase subunit SecY HVS_RS09725 cc757c2265a94a428bec15c245b40bc5 287 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 7.7E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS09725 cc757c2265a94a428bec15c245b40bc5 287 SUPERFAMILY SSF55383 56 139 1.1E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS09725 cc757c2265a94a428bec15c245b40bc5 287 Gene3D G3DSA:3.30.457.10 128 196 3.0E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS09725 cc757c2265a94a428bec15c245b40bc5 287 Gene3D G3DSA:3.30.457.10 66 127 2.9E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS09725 cc757c2265a94a428bec15c245b40bc5 287 Gene3D G3DSA:3.30.457.10 7 65 3.3E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Pfam PF01584 CheW-like domain 587 714 4.3E-17 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:1.20.120.160 7 144 2.2E-24 T 29-03-2018 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SMART SM00073 7 106 3.8E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Pfam PF01627 Hpt domain 10 86 1.4E-12 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SMART SM00260 574 714 2.8E-25 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SMART SM01231 333 395 6.9E-16 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Pfam PF07194 P2 response regulator binding domain 171 252 1.7E-18 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SUPERFAMILY SSF55052 169 252 6.8E-13 T 29-03-2018 IPR015162 CheY binding HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:2.30.30.40 660 714 1.6E-20 T 29-03-2018 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:2.30.30.40 584 616 0.022 T 29-03-2018 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 579 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 499 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 560 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 442 581 1.6E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 334 395 7.4E-14 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SUPERFAMILY SSF50341 581 714 1.83E-26 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SMART SM00387 440 582 2.6E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SUPERFAMILY SSF47226 9 131 2.09E-20 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SUPERFAMILY SSF55874 397 580 1.7E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:3.30.70.1110 169 252 7.2E-20 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:2.40.50.180 617 659 0.0022 T 29-03-2018 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:1.10.287.560 333 396 5.5E-17 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 Gene3D G3DSA:3.30.565.10 398 583 1.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09690 2812da430fef5754e7a42ff9c04ee264 715 SUPERFAMILY SSF47384 335 396 2.75E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS02585 7b71684311b026bc0636c0d5ffe9caa2 292 Pfam PF07833 Copper amine oxidase N-terminal domain 198 289 7.1E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02585 7b71684311b026bc0636c0d5ffe9caa2 292 Gene3D G3DSA:3.30.457.10 270 291 5.9E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02585 7b71684311b026bc0636c0d5ffe9caa2 292 Gene3D G3DSA:3.30.457.10 115 209 5.3E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02585 7b71684311b026bc0636c0d5ffe9caa2 292 Gene3D G3DSA:3.30.457.10 210 269 4.0E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS02585 7b71684311b026bc0636c0d5ffe9caa2 292 SUPERFAMILY SSF55383 200 284 5.36E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08410 7b2c26841711e0ef7b29cb27e12b4450 82 Gene3D G3DSA:2.30.30.100 6 70 2.6E-33 T 29-03-2018 HVS_RS08410 7b2c26841711e0ef7b29cb27e12b4450 82 Pfam PF17209 Hfq protein 8 70 5.3E-34 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 HVS_RS08410 7b2c26841711e0ef7b29cb27e12b4450 82 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 7 66 9.0E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 HVS_RS08410 7b2c26841711e0ef7b29cb27e12b4450 82 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 66 29.951 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 HVS_RS08410 7b2c26841711e0ef7b29cb27e12b4450 82 SUPERFAMILY SSF50182 7 66 4.7E-25 T 29-03-2018 IPR010920 LSM domain HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 Gene3D G3DSA:1.10.10.60 186 246 6.7E-16 T 29-03-2018 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 SUPERFAMILY SSF46689 192 242 5.05E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 Pfam PF02311 AraC-like ligand binding domain 31 98 6.8E-9 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 Pfam PF12833 Helix-turn-helix domain 215 292 3.1E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 Gene3D G3DSA:1.10.10.60 247 294 5.5E-14 T 29-03-2018 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 SMART SM00342 208 291 8.7E-33 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 291 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 275 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 Gene3D G3DSA:2.60.120.280 13 178 5.2E-23 T 29-03-2018 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 SUPERFAMILY SSF51215 31 173 1.07E-16 T 29-03-2018 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 245 287 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HVS_RS14800 f8318bd0f0dc023d8b8738cb22c8ef85 295 SUPERFAMILY SSF46689 244 294 3.54E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 Gene3D G3DSA:1.10.10.60 186 246 6.7E-16 T 29-03-2018 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 SUPERFAMILY SSF46689 192 242 5.05E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 Pfam PF02311 AraC-like ligand binding domain 31 98 6.8E-9 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 Pfam PF12833 Helix-turn-helix domain 215 292 3.1E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 Gene3D G3DSA:1.10.10.60 247 294 5.5E-14 T 29-03-2018 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 SMART SM00342 208 291 8.7E-33 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 275 291 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 275 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 Gene3D G3DSA:2.60.120.280 13 178 5.2E-23 T 29-03-2018 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 SUPERFAMILY SSF51215 31 173 1.07E-16 T 29-03-2018 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 245 287 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HVS_RS06025 f8318bd0f0dc023d8b8738cb22c8ef85 295 SUPERFAMILY SSF46689 244 294 3.54E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 276 1.7E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 Gene3D G3DSA:3.50.50.60 210 294 7.6E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 Gene3D G3DSA:3.50.50.60 126 209 8.1E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 Gene3D G3DSA:3.50.50.60 1 125 1.7E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 SUPERFAMILY SSF51905 2 149 8.78E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 SUPERFAMILY SSF51905 218 287 8.78E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 160 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 99 107 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 269 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 34 49 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 121 133 1.1E-36 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.3E-21 T 29-03-2018 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 263 3.3E-21 T 29-03-2018 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 3.3E-21 T 29-03-2018 HVS_RS01830 6ce20c48344e95908045a6bd4477875c 294 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 3.3E-21 T 29-03-2018 HVS_RS01190 11bdc50e1131c68902261c382d35f512 141 Gene3D G3DSA:2.40.50.140 1 111 8.2E-42 T 29-03-2018 HVS_RS01190 11bdc50e1131c68902261c382d35f512 141 Pfam PF00436 Single-strand binding protein family 1 102 2.2E-37 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HVS_RS01190 11bdc50e1131c68902261c382d35f512 141 Hamap MF_00984 Single-stranded DNA-binding protein. 1 107 31.782 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HVS_RS01190 11bdc50e1131c68902261c382d35f512 141 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 111 1.3E-35 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HVS_RS01190 11bdc50e1131c68902261c382d35f512 141 PIRSF PIRSF002070 1 138 4.2E-40 T 29-03-2018 HVS_RS01190 11bdc50e1131c68902261c382d35f512 141 SUPERFAMILY SSF50249 1 141 2.91E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 Pfam PF00404 Dockerin type I repeat 272 292 2.0E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 Pfam PF00404 Dockerin type I repeat 307 327 4.2E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 SUPERFAMILY SSF63446 269 332 6.38E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 SUPERFAMILY SSF49899 34 247 6.67E-56 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 Gene3D G3DSA:2.60.120.200 45 273 2.6E-45 T 29-03-2018 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 115 131 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 136 151 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 190 207 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 234 246 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 96 114 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 152 165 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 210 232 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 PRINTS PR00737 Glycosyl hydrolase family 16 signature 170 187 5.7E-62 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 Gene3D G3DSA:1.10.1330.10 274 333 3.4E-5 T 29-03-2018 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 ProSitePatterns PS01034 Glycosyl hydrolases family 16 active sites. 139 149 - T 29-03-2018 IPR008263 Glycoside hydrolase, family 16, active site GO:0004553|GO:0005975 HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 ProSitePatterns PS00018 EF-hand calcium-binding domain. 272 284 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS09035 816ea8e8ca36f78aaefcf82cdf7ae74c 333 Pfam PF00722 Glycosyl hydrolases family 16 59 226 3.5E-42 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 HVS_RS15170 1e63e471004f65ed47c85b3c737e9b49 153 Pfam PF13581 Histidine kinase-like ATPase domain 23 150 9.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15170 1e63e471004f65ed47c85b3c737e9b49 153 SUPERFAMILY SSF55874 35 141 7.07E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15170 1e63e471004f65ed47c85b3c737e9b49 153 Gene3D G3DSA:3.30.565.10 18 148 5.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 533 551 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 SMART SM00382 221 365 7.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 SMART SM00382 502 670 2.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 SMART SM01086 669 758 3.4E-18 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Gene3D G3DSA:3.40.50.300 457 668 2.7E-45 T 29-03-2018 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 SUPERFAMILY SSF52540 451 755 6.43E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 SUPERFAMILY SSF52540 181 446 2.55E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 356 2.6E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Gene3D G3DSA:3.40.50.300 208 406 5.7E-28 T 29-03-2018 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 670 747 3.0E-15 T 29-03-2018 IPR019489 Clp ATPase, C-terminal HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Gene3D G3DSA:1.10.1780.10 1 141 5.9E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 61 1.3E-4 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 506 524 5.6E-39 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 577 595 5.6E-39 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 548 566 5.6E-39 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 610 624 5.6E-39 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 SUPERFAMILY SSF81923 3 139 2.88E-34 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 316 328 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 4 750 0.0 T 29-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Gene3D G3DSA:1.10.8.60 669 761 1.6E-15 T 29-03-2018 HVS_RS06440 3fa67c40df8f0b66f5749c5d934bc026 762 Pfam PF07724 AAA domain (Cdc48 subfamily) 501 663 1.4E-46 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS12990 9165d016004c53a710f287db5260c0ab 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12990 9165d016004c53a710f287db5260c0ab 49 Pfam PF00471 Ribosomal protein L33 3 49 4.3E-23 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12990 9165d016004c53a710f287db5260c0ab 49 SUPERFAMILY SSF57829 1 49 1.01E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 HVS_RS12990 9165d016004c53a710f287db5260c0ab 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.441 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12990 9165d016004c53a710f287db5260c0ab 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 1.6E-21 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12070 bf4656c102ddf9ebadb96ad12d74eb55 143 Pfam PF13581 Histidine kinase-like ATPase domain 12 137 1.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS12070 bf4656c102ddf9ebadb96ad12d74eb55 143 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 3 141 36.337 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 HVS_RS12070 bf4656c102ddf9ebadb96ad12d74eb55 143 SUPERFAMILY SSF55874 34 135 1.19E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS12070 bf4656c102ddf9ebadb96ad12d74eb55 143 Gene3D G3DSA:3.30.565.10 3 140 4.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS12070 bf4656c102ddf9ebadb96ad12d74eb55 143 SMART SM00387 37 141 3.2E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS12070 bf4656c102ddf9ebadb96ad12d74eb55 143 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 5 137 6.0E-62 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 SUPERFAMILY SSF54211 2 182 5.57E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 Gene3D G3DSA:3.30.230.70 1 241 2.1E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 5.2E-22 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 SUPERFAMILY SSF55666 154 242 6.54E-25 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 Hamap MF_00564 Ribonuclease PH [rph]. 2 238 46.193 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 237 1.0E-114 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 HVS_RS11485 767bc5bd9803d912a47b974357ba6882 263 Pfam PF03725 3' exoribonuclease family, domain 2 160 225 2.7E-10 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 Pfam PF00155 Aminotransferase class I and II 31 389 1.5E-76 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 Gene3D G3DSA:3.40.640.10 44 272 1.8E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 SUPERFAMILY SSF53383 2 395 1.46E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 2.3E-15 T 29-03-2018 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 2.3E-15 T 29-03-2018 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 2.3E-15 T 29-03-2018 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 2.3E-15 T 29-03-2018 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 2.3E-15 T 29-03-2018 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 Gene3D G3DSA:3.90.1150.10 273 395 6.9E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS09175 84e3a9bc6811f38cd584578879ad3623 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HVS_RS04525 fd67982de459e18dc81b30ba32c7ba45 238 SMART SM00382 32 221 2.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04525 fd67982de459e18dc81b30ba32c7ba45 238 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS04525 fd67982de459e18dc81b30ba32c7ba45 238 SUPERFAMILY SSF52540 3 224 2.13E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04525 fd67982de459e18dc81b30ba32c7ba45 238 Pfam PF00005 ABC transporter 23 171 7.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS04525 fd67982de459e18dc81b30ba32c7ba45 238 Gene3D G3DSA:3.40.50.300 1 236 1.4E-63 T 29-03-2018 HVS_RS07805 8e0b4d01d0e01bc0dff5ba399632651e 269 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 7 247 3.2E-93 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 HVS_RS07805 8e0b4d01d0e01bc0dff5ba399632651e 269 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 51 91 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 HVS_RS07805 8e0b4d01d0e01bc0dff5ba399632651e 269 Gene3D G3DSA:3.40.50.1580 1 268 9.3E-45 T 29-03-2018 HVS_RS07805 8e0b4d01d0e01bc0dff5ba399632651e 269 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 5 268 39.754 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 HVS_RS07805 8e0b4d01d0e01bc0dff5ba399632651e 269 Pfam PF01048 Phosphorylase superfamily 6 246 2.0E-45 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HVS_RS07805 8e0b4d01d0e01bc0dff5ba399632651e 269 SUPERFAMILY SSF53167 4 263 1.7E-83 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 Gene3D G3DSA:3.30.70.20 3 47 2.3E-10 T 29-03-2018 HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 Gene3D G3DSA:3.30.70.20 48 277 4.0E-4 T 29-03-2018 HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 Pfam PF12838 4Fe-4S dicluster domain 12 57 8.1E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 SUPERFAMILY SSF54862 12 58 1.73E-10 T 29-03-2018 HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 71 139 2.9E-7 T 29-03-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal HVS_RS13390 975b73272ca2bfe496b73ad354d90a70 399 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 154 324 1.6E-35 T 29-03-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal HVS_RS08260 e23451f43e6498abbcfeca5b8339e1b6 841 SUPERFAMILY SSF53649 547 797 1.98E-18 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS08260 e23451f43e6498abbcfeca5b8339e1b6 841 Pfam PF00884 Sulfatase 493 731 1.1E-29 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 HVS_RS08260 e23451f43e6498abbcfeca5b8339e1b6 841 Gene3D G3DSA:3.40.720.10 483 791 1.1E-22 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 SUPERFAMILY SSF49384 573 729 2.07E-39 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 SUPERFAMILY SSF49384 48 207 5.08E-53 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Gene3D G3DSA:2.60.40.680 223 388 6.0E-42 T 29-03-2018 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Gene3D G3DSA:2.60.40.680 574 735 9.4E-34 T 29-03-2018 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Gene3D G3DSA:2.60.40.680 50 213 1.7E-40 T 29-03-2018 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Gene3D G3DSA:2.60.40.680 404 568 6.4E-45 T 29-03-2018 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 SUPERFAMILY SSF49384 224 382 1.18E-47 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Pfam PF00963 Cohesin domain 577 726 2.5E-19 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Pfam PF00963 Cohesin domain 227 382 1.5E-20 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Pfam PF00963 Cohesin domain 53 208 3.9E-22 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 Pfam PF00963 Cohesin domain 406 563 6.3E-23 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS07820 b136445ec1a2369c035020b54237a49c 735 SUPERFAMILY SSF49384 403 562 1.83E-54 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 Gene3D G3DSA:3.90.1720.10 197 332 1.2E-41 T 29-03-2018 HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 Pfam PF00877 NlpC/P60 family 221 329 3.5E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 Gene3D G3DSA:2.40.50.110 92 179 6.1E-18 T 29-03-2018 HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 SUPERFAMILY SSF50044 144 183 7.33E-5 T 29-03-2018 IPR001452 SH3 domain GO:0005515 HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 SUPERFAMILY SSF54001 209 331 1.86E-42 T 29-03-2018 HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 Pfam PF08239 Bacterial SH3 domain 125 177 2.9E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type HVS_RS07175 70ec30fec6c5256f31ee7e23b788f864 332 SMART SM00287 117 180 4.7E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type HVS_RS14965 d0b47f9fb13d495152f7c7c2bc85da8a 315 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 4 313 4.8E-80 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 HVS_RS14965 d0b47f9fb13d495152f7c7c2bc85da8a 315 SUPERFAMILY SSF53067 1 314 4.99E-66 T 29-03-2018 HVS_RS14965 d0b47f9fb13d495152f7c7c2bc85da8a 315 ProSitePatterns PS01125 ROK family signature. 136 163 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 HVS_RS14965 d0b47f9fb13d495152f7c7c2bc85da8a 315 Pfam PF00480 ROK family 3 313 3.8E-77 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 HVS_RS14965 d0b47f9fb13d495152f7c7c2bc85da8a 315 Gene3D G3DSA:3.30.420.40 122 315 2.9E-58 T 29-03-2018 HVS_RS14965 d0b47f9fb13d495152f7c7c2bc85da8a 315 Gene3D G3DSA:3.30.420.40 1 121 1.4E-31 T 29-03-2018 HVS_RS10440 741ca6064a8261fe92fa767435b12222 327 ProSitePatterns PS01347 MraY family signature 1. 55 67 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10440 741ca6064a8261fe92fa767435b12222 327 ProSitePatterns PS01348 MraY family signature 2. 173 184 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10440 741ca6064a8261fe92fa767435b12222 327 Pfam PF00953 Glycosyl transferase family 4 87 254 3.6E-37 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 HVS_RS10440 741ca6064a8261fe92fa767435b12222 327 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 12 327 21.983 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10440 741ca6064a8261fe92fa767435b12222 327 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 55 67 6.5E-4 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS10440 741ca6064a8261fe92fa767435b12222 327 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 24 325 1.8E-104 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 SUPERFAMILY SSF53187 5 174 5.03E-58 T 29-03-2018 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 SUPERFAMILY SSF53187 287 368 5.03E-58 T 29-03-2018 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 PIRSF PIRSF001123 5 86 0.0061 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 PIRSF PIRSF001123 89 180 1.9E-6 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 PIRSF PIRSF001123 259 370 6.7E-7 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 Gene3D G3DSA:3.40.630.10 272 370 3.6E-8 T 29-03-2018 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 Pfam PF07687 Peptidase dimerisation domain 180 271 4.8E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 Gene3D G3DSA:3.30.70.360 182 271 7.2E-23 T 29-03-2018 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 SUPERFAMILY SSF55031 180 287 4.06E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 Gene3D G3DSA:3.40.630.10 1 181 6.8E-26 T 29-03-2018 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 Pfam PF01546 Peptidase family M20/M25/M40 72 367 6.5E-19 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HVS_RS12050 7765dec381662e5a4091d1dfff44a0c7 370 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 366 8.6E-123 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 ProSitePatterns PS01229 Hypothetical cof family signature 2. 507 529 - T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 52 610 1.6E-125 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 594 2.6E-77 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 311 317 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 526 1.6E-20 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 542 1.6E-20 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 1.6E-20 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 1.6E-20 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 Gene3D G3DSA:2.70.150.10 8 218 2.4E-34 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 SUPERFAMILY SSF81665 556 589 6.02E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 SUPERFAMILY SSF81665 218 303 6.02E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 SUPERFAMILY SSF81665 71 120 6.02E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 Gene3D G3DSA:3.40.50.1000 432 573 1.4E-38 T 29-03-2018 IPR023214 HAD-like domain HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00943 Copper-transporting ATPase signature 237 251 2.1E-5 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00943 Copper-transporting ATPase signature 106 124 2.1E-5 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 PRINTS PR00943 Copper-transporting ATPase signature 484 501 2.1E-5 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 Pfam PF00122 E1-E2 ATPase 118 289 1.5E-48 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 66 610 1.6E-167 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 Gene3D G3DSA:3.40.1110.10 320 431 8.8E-24 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 SUPERFAMILY SSF56784 307 327 9.9E-48 T 29-03-2018 IPR023214 HAD-like domain HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 SUPERFAMILY SSF56784 363 607 9.9E-48 T 29-03-2018 IPR023214 HAD-like domain HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 Pfam PF00702 haloacid dehalogenase-like hydrolase 305 518 1.1E-33 T 29-03-2018 HVS_RS02220 20ac80b0cfeca2564c7bc5ed926a2e86 617 SUPERFAMILY SSF81653 124 217 6.02E-26 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 HVS_RS05260 6f31db11122015c813a1e606fd646d34 340 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 25 331 1.9E-110 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 HVS_RS05260 6f31db11122015c813a1e606fd646d34 340 SUPERFAMILY SSF55681 20 333 3.14E-98 T 29-03-2018 HVS_RS05260 6f31db11122015c813a1e606fd646d34 340 Pfam PF03590 Aspartate-ammonia ligase 25 250 1.3E-108 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 HVS_RS05260 6f31db11122015c813a1e606fd646d34 340 Gene3D G3DSA:3.30.930.10 12 335 1.4E-42 T 29-03-2018 HVS_RS05260 6f31db11122015c813a1e606fd646d34 340 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 16 336 50.624 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 HVS_RS05260 6f31db11122015c813a1e606fd646d34 340 PIRSF PIRSF001555 12 340 3.4E-161 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 Gene3D G3DSA:3.30.420.40 2 196 2.0E-79 T 29-03-2018 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 SUPERFAMILY SSF53067 1 196 4.53E-73 T 29-03-2018 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 Pfam PF00871 Acetokinase family 2 390 1.9E-165 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PIRSF PIRSF000722 1 400 7.1E-165 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 SUPERFAMILY SSF53067 158 397 1.45E-96 T 29-03-2018 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 TIGRFAM TIGR00016 ackA: acetate kinase 1 396 2.4E-168 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 Hamap MF_00020 Acetate kinase [ackA]. 1 399 197.098 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 Gene3D G3DSA:3.30.420.40 197 400 9.0E-85 T 29-03-2018 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PRINTS PR00471 Acetate kinase family signature 3 14 5.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PRINTS PR00471 Acetate kinase family signature 323 339 5.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PRINTS PR00471 Acetate kinase family signature 174 187 5.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PRINTS PR00471 Acetate kinase family signature 204 225 5.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PRINTS PR00471 Acetate kinase family signature 377 389 5.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 PRINTS PR00471 Acetate kinase family signature 301 314 5.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS07260 0cfffb2a16ce8f2023c6c3df854f069c 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 HVS_RS03150 832c12a1d654a845337ba2225699e114 989 SUPERFAMILY SSF54001 720 752 1.44E-18 T 29-03-2018 HVS_RS03150 832c12a1d654a845337ba2225699e114 989 SUPERFAMILY SSF54001 785 865 1.44E-18 T 29-03-2018 HVS_RS03150 832c12a1d654a845337ba2225699e114 989 Gene3D G3DSA:3.90.1720.10 718 918 1.1E-21 T 29-03-2018 HVS_RS03150 832c12a1d654a845337ba2225699e114 989 Pfam PF00877 NlpC/P60 family 778 861 5.8E-13 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain HVS_RS03150 832c12a1d654a845337ba2225699e114 989 Gene3D G3DSA:1.10.101.10 608 691 3.4E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03150 832c12a1d654a845337ba2225699e114 989 Gene3D G3DSA:2.60.40.10 231 299 2.2E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS03150 832c12a1d654a845337ba2225699e114 989 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 232 297 4.9E-14 T 29-03-2018 HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 SUPERFAMILY SSF55729 379 517 2.66E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 SUPERFAMILY SSF56784 186 308 3.22E-10 T 29-03-2018 IPR023214 HAD-like domain HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 Gene3D G3DSA:3.40.50.1000 185 310 2.0E-11 T 29-03-2018 IPR023214 HAD-like domain HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 188 310 1.2E-23 T 29-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 Pfam PF03031 NLI interacting factor-like phosphatase 188 309 3.5E-7 T 29-03-2018 IPR004274 FCP1 homology domain HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 Gene3D G3DSA:3.40.630.30 378 526 3.4E-8 T 29-03-2018 HVS_RS04430 e9602fef191fffe3d5ecb4bde378fea5 548 TIGRFAM TIGR01686 FkbH: FkbH domain 187 514 2.1E-95 T 29-03-2018 IPR010037 FkbH domain HVS_RS08085 136a054897d02e24bd218074226ea16e 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 219 3.3E-76 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HVS_RS08085 136a054897d02e24bd218074226ea16e 225 Hamap MF_00238 Cytidylate kinase [cmk]. 6 225 34.182 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HVS_RS08085 136a054897d02e24bd218074226ea16e 225 SUPERFAMILY SSF52540 6 224 7.25E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08085 136a054897d02e24bd218074226ea16e 225 Gene3D G3DSA:3.40.50.300 5 223 1.6E-49 T 29-03-2018 HVS_RS08085 136a054897d02e24bd218074226ea16e 225 Pfam PF02224 Cytidylate kinase 8 222 1.9E-74 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 HVS_RS04085 8d4d5241511ed4a6188dd5ebc382a04a 138 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 113 137 1.3E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS04085 8d4d5241511ed4a6188dd5ebc382a04a 138 SUPERFAMILY SSF51294 5 137 2.09E-24 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04085 8d4d5241511ed4a6188dd5ebc382a04a 138 Gene3D G3DSA:2.170.16.10 4 136 1.8E-35 T 29-03-2018 HVS_RS04085 8d4d5241511ed4a6188dd5ebc382a04a 138 SMART SM00306 1 94 1.1E-4 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04085 8d4d5241511ed4a6188dd5ebc382a04a 138 Pfam PF07591 Pretoxin HINT domain 8 137 3.0E-30 T 29-03-2018 HVS_RS11070 6c4cca284e6db70e8e89693f5a8bfb3b 74 Gene3D G3DSA:3.90.940.10 7 74 8.7E-24 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 HVS_RS11070 6c4cca284e6db70e8e89693f5a8bfb3b 74 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 7 67 15.273 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS11070 6c4cca284e6db70e8e89693f5a8bfb3b 74 SUPERFAMILY SSF63562 7 69 3.79E-23 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 HVS_RS11070 6c4cca284e6db70e8e89693f5a8bfb3b 74 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 7 64 1.3E-18 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HVS_RS11070 6c4cca284e6db70e8e89693f5a8bfb3b 74 SMART SM01409 14 66 3.5E-18 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 HVS_RS11070 6c4cca284e6db70e8e89693f5a8bfb3b 74 Pfam PF01192 RNA polymerase Rpb6 15 66 1.5E-17 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 HVS_RS04705 8e9b3c803c2db887527c844a6d812209 178 SUPERFAMILY SSF54001 105 167 9.16E-12 T 29-03-2018 HVS_RS04705 8e9b3c803c2db887527c844a6d812209 178 Pfam PF01841 Transglutaminase-like superfamily 95 173 1.1E-13 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 SUPERFAMILY SSF51735 7 250 3.41E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 PIRSF PIRSF000094 1 252 2.9E-101 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 1.0E-84 T 29-03-2018 HVS_RS05475 e81a3e59f8e91c89b450e6788a395642 252 Gene3D G3DSA:3.40.50.720 1 251 8.5E-46 T 29-03-2018 HVS_RS12840 b6d0058998fff0b852bdfebe4bad964c 292 Gene3D G3DSA:3.20.20.140 2 80 7.9E-22 T 29-03-2018 HVS_RS12840 b6d0058998fff0b852bdfebe4bad964c 292 Gene3D G3DSA:3.20.20.140 81 263 1.5E-28 T 29-03-2018 HVS_RS12840 b6d0058998fff0b852bdfebe4bad964c 292 SMART SM00481 5 70 4.0E-20 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HVS_RS12840 b6d0058998fff0b852bdfebe4bad964c 292 Pfam PF02811 PHP domain 6 164 5.9E-15 T 29-03-2018 IPR004013 PHP domain GO:0003824 HVS_RS12840 b6d0058998fff0b852bdfebe4bad964c 292 SUPERFAMILY SSF89550 166 258 2.22E-48 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS12840 b6d0058998fff0b852bdfebe4bad964c 292 SUPERFAMILY SSF89550 1 84 2.22E-48 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS06245 650f9c738eb95d43888188873729368b 420 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 1.7E-172 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Gene3D G3DSA:3.90.600.10 328 420 2.3E-33 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 SUPERFAMILY SSF56059 102 320 6.9E-60 T 29-03-2018 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 419 1.6E-28 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 3.6E-33 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 SMART SM01209 101 294 3.0E-128 T 29-03-2018 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 41.293 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Gene3D G3DSA:3.30.1490.20 85 188 2.5E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 294 2.2E-84 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 SMART SM01210 328 420 2.2E-43 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 HVS_RS06245 650f9c738eb95d43888188873729368b 420 Gene3D G3DSA:3.40.50.20 2 84 2.6E-35 T 29-03-2018 HVS_RS06245 650f9c738eb95d43888188873729368b 420 SUPERFAMILY SSF52440 1 101 1.87E-32 T 29-03-2018 IPR016185 Pre-ATP-grasp domain HVS_RS06245 650f9c738eb95d43888188873729368b 420 Gene3D G3DSA:3.30.470.20 190 326 7.2E-62 T 29-03-2018 HVS_RS06245 650f9c738eb95d43888188873729368b 420 SUPERFAMILY SSF51246 329 419 2.83E-29 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 SMART SM00862 151 227 1.4E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 SMART SM00448 3 115 2.1E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 Pfam PF00072 Response regulator receiver domain 5 116 9.3E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.2E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 Gene3D G3DSA:3.40.50.2300 2 126 2.4E-33 T 29-03-2018 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 SUPERFAMILY SSF46894 127 228 5.39E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 SUPERFAMILY SSF52172 3 127 5.55E-38 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS13080 946cb13e65d83717f1f214c7b2c0618f 233 Gene3D G3DSA:1.10.10.10 127 233 3.4E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 PIRSF PIRSF000615 67 214 4.9E-13 T 29-03-2018 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 PIRSF PIRSF000615 250 371 20.0 T 29-03-2018 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 Gene3D G3DSA:3.30.200.20 3 78 6.1E-23 T 29-03-2018 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 SMART SM00740 492 558 0.039 T 29-03-2018 IPR005543 PASTA domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 SMART SM00740 354 422 2.4E-7 T 29-03-2018 IPR005543 PASTA domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 SMART SM00740 423 489 1.1E-11 T 29-03-2018 IPR005543 PASTA domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 Pfam PF00069 Protein kinase domain 10 263 4.1E-57 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 Pfam PF03793 PASTA domain 497 554 2.9E-8 T 29-03-2018 IPR005543 PASTA domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 Pfam PF03793 PASTA domain 428 485 9.1E-11 T 29-03-2018 IPR005543 PASTA domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 Pfam PF03793 PASTA domain 359 422 2.3E-9 T 29-03-2018 IPR005543 PASTA domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 SUPERFAMILY SSF56112 6 269 1.89E-85 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 SMART SM00220 10 267 8.4E-71 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HVS_RS07065 818ff2820f81896a6e41a670bc413422 641 Gene3D G3DSA:1.10.510.10 79 386 3.0E-57 T 29-03-2018 HVS_RS10235 47ecbe785afaf5fdef07a934b208f87c 266 Gene3D G3DSA:1.20.120.330 55 160 1.6E-5 T 29-03-2018 HVS_RS10235 47ecbe785afaf5fdef07a934b208f87c 266 Gene3D G3DSA:1.10.220.30 183 263 3.5E-10 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HVS_RS10235 47ecbe785afaf5fdef07a934b208f87c 266 SUPERFAMILY SSF158791 158 255 2.88E-7 T 29-03-2018 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 Pfam PF14842 FliG N-terminal domain 9 112 1.2E-38 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 SUPERFAMILY SSF48029 11 105 5.1E-23 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 Pfam PF01706 FliG C-terminal domain 222 330 2.9E-42 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 SUPERFAMILY SSF48029 119 331 1.19E-70 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 Pfam PF14841 FliG middle domain 120 194 2.8E-33 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 Gene3D G3DSA:1.10.220.30 88 196 1.5E-22 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 Gene3D G3DSA:1.10.220.30 9 87 1.7E-16 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 Gene3D G3DSA:1.10.220.30 200 340 7.3E-37 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PIRSF PIRSF003161 4 340 2.7E-122 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 8 340 7.9E-141 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 1.2E-69 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 1.2E-69 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 278 304 1.2E-69 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 1.2E-69 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 1.2E-69 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS10255 fb291c84c079d2d7ccbc6d4ea82db36b 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 1.2E-69 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 Gene3D G3DSA:3.30.1600.10 103 157 3.8E-19 T 29-03-2018 IPR026591 Sirtuin family, catalytic core small domain HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 SUPERFAMILY SSF52467 3 241 7.01E-80 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 Gene3D G3DSA:3.30.1600.10 41 102 3.2E-16 T 29-03-2018 IPR026591 Sirtuin family, catalytic core small domain HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 4 241 59.896 T 29-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 Gene3D G3DSA:3.40.50.1220 158 243 8.1E-20 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 Pfam PF02146 Sir2 family 20 198 1.4E-49 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 HVS_RS04870 58c31b669c6b387ec8aec04cf4c3f9db 243 Gene3D G3DSA:3.40.50.1220 2 40 1.8E-4 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 3 123 5.3E-47 T 29-03-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 7 37 1.9E-15 T 29-03-2018 IPR004462 Desulforodoxin domain GO:0005506 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 6 34 1.0E-14 T 29-03-2018 IPR004462 Desulforodoxin domain GO:0005506 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 Pfam PF01880 Desulfoferrodoxin 43 123 2.7E-21 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 41 123 6.5E-22 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 SUPERFAMILY SSF57802 5 37 3.61E-11 T 29-03-2018 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 Gene3D G3DSA:2.60.40.730 2 125 7.6E-49 T 29-03-2018 HVS_RS15395 acc074570d1578e67420f1991deefaf0 126 SUPERFAMILY SSF49367 39 124 8.63E-31 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 SUPERFAMILY SSF53850 3 186 2.06E-53 T 29-03-2018 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 159 181 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 Pfam PF01842 ACT domain 194 255 1.2E-8 T 29-03-2018 IPR002912 ACT domain HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 SUPERFAMILY SSF55021 178 273 5.29E-28 T 29-03-2018 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 Gene3D G3DSA:3.40.190.10 1 95 1.3E-26 T 29-03-2018 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 Gene3D G3DSA:3.40.190.10 96 172 2.5E-25 T 29-03-2018 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 221 228 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 Pfam PF00800 Prephenate dehydratase 4 184 4.5E-58 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 HVS_RS01295 c9d2110c7244648102a04d07a7f2f842 278 Gene3D G3DSA:3.30.70.260 186 276 6.2E-31 T 29-03-2018 HVS_RS09620 66f93bca05abc0243ee50eec3dbd2a2b 81 Pfam PF07875 Coat F domain 2 63 5.3E-25 T 29-03-2018 IPR012851 Spore coat protein CotF-like HVS_RS09620 66f93bca05abc0243ee50eec3dbd2a2b 81 Gene3D G3DSA:1.20.1260.10 1 60 1.7E-11 T 29-03-2018 IPR012347 Ferritin-related HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Gene3D G3DSA:1.10.150.130 462 576 0.015 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 SMART SM00471 42 154 1.0E-9 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Pfam PF04607 Region found in RelA / SpoT proteins 236 346 6.3E-40 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Pfam PF02824 TGS domain 387 446 7.5E-23 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Pfam PF13328 HD domain 29 176 6.2E-51 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Gene3D G3DSA:3.30.460.10 189 327 3.7E-45 T 29-03-2018 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 SUPERFAMILY SSF55021 646 722 6.49E-12 T 29-03-2018 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 SUPERFAMILY SSF81271 374 447 3.92E-24 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 28 722 8.6E-260 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Gene3D G3DSA:3.30.70.260 645 725 3.0E-11 T 29-03-2018 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 SUPERFAMILY SSF109604 5 191 2.17E-75 T 29-03-2018 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Pfam PF13291 ACT domain 645 722 3.8E-21 T 29-03-2018 IPR002912 ACT domain HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 SMART SM00954 236 346 1.1E-68 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 Gene3D G3DSA:3.10.20.30 381 454 7.5E-25 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS11175 1485e01f32e942e4da5b702a9717ee62 725 SUPERFAMILY SSF81301 181 391 1.6E-68 T 29-03-2018 HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Gene3D G3DSA:2.120.10.30 303 594 7.4E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 SUPERFAMILY SSF69304 724 831 5.75E-10 T 29-03-2018 HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 SUPERFAMILY SSF69304 509 671 5.75E-10 T 29-03-2018 HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Gene3D G3DSA:2.130.10.10 595 864 5.8E-6 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 779 811 3.4E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 600 640 6.6E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 712 747 1.0E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 838 871 6.0E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 880 912 5.4E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 474 511 1.8E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 579 615 5.1E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 984 1018 5.0E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 796 832 6.3E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 754 791 1.5E-8 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Pfam PF05593 RHS Repeat 1046 1078 4.3E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 SUPERFAMILY SSF69304 792 1016 1.83E-6 T 29-03-2018 HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 389 424 7.6E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 817 858 1.9E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 922 957 2.1E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 859 900 6.8E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 754 795 9.8E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 733 774 1.3E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 712 747 4.5E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 463 494 3.1E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 579 619 2.8E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 356 388 0.0018 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 499 532 7.5E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 880 921 3.1E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 796 822 4.4E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 691 729 1.1E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 984 1022 1.9E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1025 1066 2.5E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1303 1382 2.0E-19 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS04850 eba611dd7c2e31ae787e23579ace818b 1575 Gene3D G3DSA:2.60.40.10 57 155 8.3E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Gene3D G3DSA:3.40.1190.10 93 312 2.1E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 455 3.8E-138 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 456 34.576 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Pfam PF08245 Mur ligase middle domain 109 295 9.2E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Pfam PF01225 Mur ligase family, catalytic domain 26 98 7.6E-11 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Gene3D G3DSA:3.90.190.20 316 457 6.0E-44 T 29-03-2018 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Gene3D G3DSA:3.40.1390.10 4 92 2.1E-27 T 29-03-2018 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 SUPERFAMILY SSF53623 103 315 2.35E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 SUPERFAMILY SSF53244 317 455 1.68E-33 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 SUPERFAMILY SSF63418 3 101 5.23E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HVS_RS10445 0ae8d8e3683a0c1808ad58355c2d811b 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 398 7.1E-16 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS11630 5fc2890966b846a05b251c3d8600be09 183 Pfam PF01966 HD domain 20 102 3.6E-10 T 29-03-2018 IPR006674 HD domain HVS_RS11630 5fc2890966b846a05b251c3d8600be09 183 Gene3D G3DSA:1.10.3210.10 1 181 4.2E-12 T 29-03-2018 HVS_RS11630 5fc2890966b846a05b251c3d8600be09 183 SMART SM00471 15 123 1.6E-5 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS11630 5fc2890966b846a05b251c3d8600be09 183 TIGRFAM TIGR00277 HDIG: HDIG domain 17 90 3.9E-14 T 29-03-2018 IPR006675 HDIG domain HVS_RS11630 5fc2890966b846a05b251c3d8600be09 183 SUPERFAMILY SSF109604 4 174 4.71E-24 T 29-03-2018 HVS_RS14695 973446e65389c654e213605a3590c3df 283 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 65 78 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS14695 973446e65389c654e213605a3590c3df 283 SUPERFAMILY SSF51717 16 282 6.02E-102 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS14695 973446e65389c654e213605a3590c3df 283 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 31 279 1.4E-98 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 HVS_RS14695 973446e65389c654e213605a3590c3df 283 Gene3D G3DSA:3.20.20.20 10 283 3.5E-109 T 29-03-2018 HVS_RS14695 973446e65389c654e213605a3590c3df 283 Pfam PF00809 Pterin binding enzyme 32 265 9.2E-88 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS14695 973446e65389c654e213605a3590c3df 283 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 31 46 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS08975 b749022df29cfbd0585c0b9a96c343da 176 PIRSF PIRSF015617 1 176 1.1E-54 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 HVS_RS08975 b749022df29cfbd0585c0b9a96c343da 176 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 3 176 2.1E-57 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 HVS_RS08975 b749022df29cfbd0585c0b9a96c343da 176 SUPERFAMILY SSF52540 2 176 2.86E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08975 b749022df29cfbd0585c0b9a96c343da 176 Gene3D G3DSA:3.40.50.300 1 176 7.9E-62 T 29-03-2018 HVS_RS08835 b79ba3fcb174e57da47afb8c0a1044a6 339 Pfam PF02504 Fatty acid synthesis protein 2 321 7.5E-107 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 HVS_RS08835 b79ba3fcb174e57da47afb8c0a1044a6 339 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 337 129.904 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 HVS_RS08835 b79ba3fcb174e57da47afb8c0a1044a6 339 SUPERFAMILY SSF53659 2 330 1.03E-92 T 29-03-2018 HVS_RS08835 b79ba3fcb174e57da47afb8c0a1044a6 339 Gene3D G3DSA:3.40.718.10 1 332 1.2E-98 T 29-03-2018 HVS_RS08835 b79ba3fcb174e57da47afb8c0a1044a6 339 PIRSF PIRSF002465 1 334 2.3E-118 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 HVS_RS08835 b79ba3fcb174e57da47afb8c0a1044a6 339 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 331 5.0E-103 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 HVS_RS12200 4c7fc41abf9b34363d1bf8b483fdadc6 147 SUPERFAMILY SSF55021 71 139 4.07E-8 T 29-03-2018 HVS_RS12200 4c7fc41abf9b34363d1bf8b483fdadc6 147 Hamap MF_00707 UPF0735 ACT domain-containing protein . 3 147 32.742 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein HVS_RS12200 4c7fc41abf9b34363d1bf8b483fdadc6 147 Pfam PF13291 ACT domain 72 140 4.5E-6 T 29-03-2018 IPR002912 ACT domain HVS_RS12200 4c7fc41abf9b34363d1bf8b483fdadc6 147 PIRSF PIRSF025624 1 147 1.5E-55 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein HVS_RS12200 4c7fc41abf9b34363d1bf8b483fdadc6 147 Gene3D G3DSA:3.30.70.260 68 141 1.5E-11 T 29-03-2018 HVS_RS00680 c13662adf624bcd1da3362de8e07028d 131 Gene3D G3DSA:3.40.1350.10 6 112 2.2E-6 T 29-03-2018 HVS_RS02255 fc50ea1f3485a3b2c433609f4413f0ed 539 SUPERFAMILY SSF51735 12 316 1.69E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS02255 fc50ea1f3485a3b2c433609f4413f0ed 539 Gene3D G3DSA:1.10.1040.10 318 539 5.6E-61 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HVS_RS02255 fc50ea1f3485a3b2c433609f4413f0ed 539 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 39 179 2.9E-14 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 HVS_RS02255 fc50ea1f3485a3b2c433609f4413f0ed 539 Gene3D G3DSA:3.40.50.720 7 315 1.0E-77 T 29-03-2018 HVS_RS02255 fc50ea1f3485a3b2c433609f4413f0ed 539 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 239 510 2.1E-28 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 HVS_RS02255 fc50ea1f3485a3b2c433609f4413f0ed 539 SUPERFAMILY SSF48179 323 537 8.16E-39 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 SMART SM00861 3 167 1.2E-61 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 Pfam PF02780 Transketolase, C-terminal domain 179 299 5.1E-36 T 29-03-2018 IPR033248 Transketolase, C-terminal domain HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 SUPERFAMILY SSF52922 174 307 9.82E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 Pfam PF02779 Transketolase, pyrimidine binding domain 2 164 2.7E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 Gene3D G3DSA:3.40.50.970 1 178 3.0E-51 T 29-03-2018 HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 SUPERFAMILY SSF52518 3 168 7.5E-58 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS14460 6275460bd4c8d3430be231f0406665cf 311 Gene3D G3DSA:3.40.50.920 179 311 1.9E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 423 441 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 672 691 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 Pfam PF00759 Glycosyl hydrolase family 9 34 447 1.2E-118 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 SUPERFAMILY SSF49384 470 625 2.25E-42 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 SUPERFAMILY SSF48208 32 464 2.12E-133 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 SMART SM01067 472 556 1.0E-28 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 Gene3D G3DSA:1.10.1330.10 632 698 0.0022 T 29-03-2018 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 Gene3D G3DSA:1.50.10.10 33 454 1.6E-111 T 29-03-2018 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 Gene3D G3DSA:2.60.40.710 460 631 4.3E-36 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 SUPERFAMILY SSF63446 632 698 8.63E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 373 389 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS02490 274f7cf90d6737e9c43086ea8d9cf417 698 Pfam PF00942 Cellulose binding domain 474 555 2.1E-13 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 Pfam PF00942 Cellulose binding domain 475 556 7.3E-12 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 Pfam PF00759 Glycosyl hydrolase family 9 20 448 5.7E-139 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 424 442 - T 29-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 SUPERFAMILY SSF48208 17 465 7.42E-164 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 SUPERFAMILY SSF63446 650 722 1.37E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 SMART SM01067 473 557 1.3E-21 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 Gene3D G3DSA:2.60.40.710 471 625 5.1E-35 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 Gene3D G3DSA:1.50.10.10 19 456 1.1E-133 T 29-03-2018 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 374 390 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS06940 692b9af2617f765aa45be630320e2a03 728 SUPERFAMILY SSF49384 472 626 1.67E-42 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 SUPERFAMILY SSF52540 17 195 4.4E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 Pfam PF07670 Nucleoside recognition 465 556 1.9E-8 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 Pfam PF07670 Nucleoside recognition 303 395 6.2E-14 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 Pfam PF02421 Ferrous iron transport protein B 18 171 1.1E-50 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 Gene3D G3DSA:3.40.50.300 8 225 8.8E-38 T 29-03-2018 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 170 7.9E-17 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 19 39 8.1E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 67 82 8.1E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 40 58 8.1E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10400 017a43655731f346fb751d6d259d8f74 588 Pfam PF07664 Ferrous iron transport protein B C terminus 403 451 3.8E-10 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 Gene3D G3DSA:3.30.70.580 1 105 8.4E-35 T 29-03-2018 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 PIRSF PIRSF001430 1 244 2.9E-84 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 Pfam PF01416 tRNA pseudouridine synthase 8 104 4.8E-11 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 Pfam PF01416 tRNA pseudouridine synthase 143 244 3.5E-27 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 36.404 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 Gene3D G3DSA:3.30.70.660 106 243 7.2E-38 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 239 3.9E-66 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14960 630345cb21b322324aa264f7b563a67e 244 SUPERFAMILY SSF55120 1 244 1.09E-85 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS14335 9efd88a47c5a3a64a3a7b5fd8a993cb5 374 Pfam PF01551 Peptidase family M23 274 368 9.7E-36 T 29-03-2018 IPR016047 Peptidase M23 HVS_RS14335 9efd88a47c5a3a64a3a7b5fd8a993cb5 374 SUPERFAMILY SSF51261 203 371 1.05E-60 T 29-03-2018 IPR011055 Duplicated hybrid motif HVS_RS14335 9efd88a47c5a3a64a3a7b5fd8a993cb5 374 Gene3D G3DSA:1.20.5.320 152 243 4.0E-5 T 29-03-2018 HVS_RS14335 9efd88a47c5a3a64a3a7b5fd8a993cb5 374 Gene3D G3DSA:2.70.70.10 244 374 2.3E-44 T 29-03-2018 HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 PIRSF PIRSF000379 2 744 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 SUPERFAMILY SSF51998 3 743 1.97E-275 T 29-03-2018 HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 Pfam PF02901 Pyruvate formate lyase-like 16 603 6.8E-202 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 Gene3D G3DSA:3.20.70.20 1 744 4.5E-285 T 29-03-2018 HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 Pfam PF01228 Glycine radical 619 725 9.5E-40 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 ProSitePatterns PS00850 Glycine radical domain signature. 714 722 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site HVS_RS12365 2f340e10881aa559bb8bac750ec5354e 744 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 5 744 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 HVS_RS13915 659764ec6071e0a65421252e407b4a58 234 Gene3D G3DSA:3.30.70.20 44 75 1.0E-5 T 29-03-2018 HVS_RS13915 659764ec6071e0a65421252e407b4a58 234 SUPERFAMILY SSF54862 4 76 1.36E-20 T 29-03-2018 HVS_RS13915 659764ec6071e0a65421252e407b4a58 234 Gene3D G3DSA:3.30.70.20 2 21 6.5E-7 T 29-03-2018 HVS_RS13915 659764ec6071e0a65421252e407b4a58 234 Gene3D G3DSA:3.30.70.20 22 43 3.6E-15 T 29-03-2018 HVS_RS13915 659764ec6071e0a65421252e407b4a58 234 Pfam PF14697 4Fe-4S dicluster domain 7 59 4.7E-10 T 29-03-2018 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 Gene3D G3DSA:3.20.20.10 38 283 1.3E-55 T 29-03-2018 IPR029066 PLP-binding barrel HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 42 298 8.2E-61 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 SUPERFAMILY SSF51419 30 300 4.65E-80 T 29-03-2018 IPR029066 PLP-binding barrel HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 431 3.5E-148 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 SUPERFAMILY SSF50621 277 435 3.98E-54 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 82 99 1.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 399 421 1.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 171 180 1.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 317 335 1.7E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 86 389 1.0E-17 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 432 40.317 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 82 2.7E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 2.7E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 389 402 2.7E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 84 96 2.7E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 288 307 2.7E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 HVS_RS09465 f45e94c91b05a61c39246f3d6e75d165 437 Gene3D G3DSA:2.40.37.10 284 437 2.3E-46 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HVS_RS03390 d4baada116dc62c8a3db1b5dd7803c2b 345 SUPERFAMILY SSF51735 1 325 4.38E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS03390 d4baada116dc62c8a3db1b5dd7803c2b 345 Gene3D G3DSA:3.40.50.720 1 316 4.0E-50 T 29-03-2018 HVS_RS03390 d4baada116dc62c8a3db1b5dd7803c2b 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 225 3.0E-37 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HVS_RS13295 74ca2acf34d71351961fdf16597ae14f 216 SMART SM00855 2 162 0.0012 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HVS_RS13295 74ca2acf34d71351961fdf16597ae14f 216 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 197 2.1E-15 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HVS_RS13295 74ca2acf34d71351961fdf16597ae14f 216 Gene3D G3DSA:3.40.50.1240 1 216 3.0E-23 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS13295 74ca2acf34d71351961fdf16597ae14f 216 SUPERFAMILY SSF53254 1 212 2.2E-21 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 Pfam PF00106 short chain dehydrogenase 2 178 9.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 2.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 127 2.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 2.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 SUPERFAMILY SSF51735 1 207 9.28E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12730 625ced047c3b302fccfbc645e390f53b 233 Gene3D G3DSA:3.40.50.720 2 229 7.7E-41 T 29-03-2018 HVS_RS09485 54290c32d21c23c0c692256693c5a14e 335 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 57 187 3.7E-64 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS09485 54290c32d21c23c0c692256693c5a14e 335 Gene3D G3DSA:1.10.8.300 224 331 1.6E-31 T 29-03-2018 HVS_RS09485 54290c32d21c23c0c692256693c5a14e 335 Gene3D G3DSA:3.40.50.300 38 223 3.1E-24 T 29-03-2018 HVS_RS09485 54290c32d21c23c0c692256693c5a14e 335 SUPERFAMILY SSF52540 22 306 2.03E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09485 54290c32d21c23c0c692256693c5a14e 335 PIRSF PIRSF002849 3 335 3.7E-129 T 29-03-2018 HVS_RS02400 18644b27856cbc38ca5326673e85eee6 73 SUPERFAMILY SSF56209 5 63 3.66E-9 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 HVS_RS02400 18644b27856cbc38ca5326673e85eee6 73 Gene3D G3DSA:3.90.330.10 1 66 1.5E-9 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 Pfam PF01632 Ribosomal protein L35 2 61 2.0E-26 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.1E-27 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 SUPERFAMILY SSF143034 2 64 2.49E-24 T 29-03-2018 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.838 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 7.0E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 7.0E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 7.0E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HVS_RS06400 901d84e5d8d0cad13bc547c2752473e0 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15505 6cc5960b9b6ccda625cb4c479127dd3b 1640 Gene3D G3DSA:2.60.40.10 946 1025 0.12 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15505 6cc5960b9b6ccda625cb4c479127dd3b 1640 Gene3D G3DSA:2.60.40.10 428 632 6.9E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15505 6cc5960b9b6ccda625cb4c479127dd3b 1640 Gene3D G3DSA:2.60.40.10 662 937 7.1E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15505 6cc5960b9b6ccda625cb4c479127dd3b 1640 Pfam PF00395 S-layer homology domain 1586 1627 1.8E-4 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS15505 6cc5960b9b6ccda625cb4c479127dd3b 1640 SUPERFAMILY SSF49265 35 106 1.24E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15505 6cc5960b9b6ccda625cb4c479127dd3b 1640 Gene3D G3DSA:2.60.40.10 29 117 3.7E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 SMART SM00966 85 130 4.2E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 Gene3D G3DSA:1.10.10.60 3 25 0.001 T 29-03-2018 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 Gene3D G3DSA:3.30.1190.10 26 80 1.2E-13 T 29-03-2018 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 SUPERFAMILY SSF47413 2 63 9.38E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 SUPERFAMILY SSF89447 81 126 2.62E-10 T 29-03-2018 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 Gene3D G3DSA:2.10.260.10 84 127 2.7E-12 T 29-03-2018 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 77 136 0.001 T 29-03-2018 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 Pfam PF01381 Helix-turn-helix 8 59 3.0E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 85 125 2.1E-14 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS14145 48d4e44ccc16cbd1aa04337daac9d20f 146 SMART SM00530 5 60 3.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS02430 1303c7a9389c436b391652adee27202f 313 PIRSF PIRSF002849 1 309 2.7E-127 T 29-03-2018 HVS_RS02430 1303c7a9389c436b391652adee27202f 313 Gene3D G3DSA:3.40.50.300 16 182 6.6E-24 T 29-03-2018 HVS_RS02430 1303c7a9389c436b391652adee27202f 313 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 35 164 6.1E-60 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS02430 1303c7a9389c436b391652adee27202f 313 SUPERFAMILY SSF52540 5 279 6.51E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02430 1303c7a9389c436b391652adee27202f 313 Gene3D G3DSA:1.10.8.300 196 304 1.6E-31 T 29-03-2018 HVS_RS06285 947edf29a068a5748a9651b375dc015b 206 Pfam PF10646 Sporulation and spore germination 76 184 2.1E-23 T 29-03-2018 IPR019606 GerMN domain HVS_RS06285 947edf29a068a5748a9651b375dc015b 206 SMART SM00909 101 189 2.4E-28 T 29-03-2018 IPR019606 GerMN domain HVS_RS06285 947edf29a068a5748a9651b375dc015b 206 Gene3D G3DSA:3.40.190.10 1 120 4.0E-4 T 29-03-2018 HVS_RS10190 35cb483670f9b622a6d3deff9a541194 120 Gene3D G3DSA:3.40.50.2300 1 120 7.6E-40 T 29-03-2018 HVS_RS10190 35cb483670f9b622a6d3deff9a541194 120 Pfam PF00072 Response regulator receiver domain 5 116 1.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10190 35cb483670f9b622a6d3deff9a541194 120 SMART SM00448 3 115 1.7E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10190 35cb483670f9b622a6d3deff9a541194 120 SUPERFAMILY SSF52172 3 120 6.12E-40 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 Gene3D G3DSA:1.10.601.10 7 97 4.6E-21 T 29-03-2018 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 SUPERFAMILY SSF88659 178 249 9.53E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 Gene3D G3DSA:1.10.10.10 176 254 2.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 Pfam PF04545 Sigma-70, region 4 196 244 5.5E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 PRINTS PR00046 Major sigma-70 factor signature 54 67 8.3E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 PRINTS PR00046 Major sigma-70 factor signature 78 86 8.3E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 PRINTS PR00046 Major sigma-70 factor signature 200 212 8.3E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 PRINTS PR00046 Major sigma-70 factor signature 217 232 8.3E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 PRINTS PR00046 Major sigma-70 factor signature 232 243 8.3E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 Gene3D G3DSA:1.10.10.10 100 147 3.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 217 243 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 SUPERFAMILY SSF88659 100 166 3.66E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 SUPERFAMILY SSF88946 8 99 2.98E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 27 247 5.8E-82 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 Pfam PF04542 Sigma-70 region 2 27 99 2.8E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 Pfam PF04539 Sigma-70 region 3 109 170 1.7E-9 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 247 4.4E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10110 aad8bcac776f394e5ebfb3df0731da2f 256 PIRSF PIRSF000770 7 254 2.3E-49 T 29-03-2018 HVS_RS05205 5ce323fc19ef55ef3f077fbb0bfdd3a2 228 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 2 214 3.6E-62 T 29-03-2018 IPR005224 Sugar fermentation stimulation protein HVS_RS05205 5ce323fc19ef55ef3f077fbb0bfdd3a2 228 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 228 48.027 T 29-03-2018 IPR005224 Sugar fermentation stimulation protein HVS_RS05205 5ce323fc19ef55ef3f077fbb0bfdd3a2 228 Pfam PF03749 Sugar fermentation stimulation protein 12 219 5.0E-75 T 29-03-2018 IPR005224 Sugar fermentation stimulation protein HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 SUPERFAMILY SSF63862 148 210 8.37E-12 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 18 125 1.2E-24 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 Gene3D G3DSA:3.40.50.10240 1 118 3.0E-30 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 Gene3D G3DSA:2.60.120.320 119 211 1.6E-22 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 207 3.7E-58 T 29-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 141 204 4.6E-17 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 SUPERFAMILY SSF63999 4 131 1.44E-32 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS07080 02e2f16022b8a4ec4f8946815b826611 211 SMART SM00983 134 205 6.2E-16 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 Pfam PF04851 Type III restriction enzyme, res subunit 279 480 6.0E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 Gene3D G3DSA:3.40.50.300 256 497 1.7E-25 T 29-03-2018 HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 SUPERFAMILY SSF52540 469 529 8.38E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 SUPERFAMILY SSF52540 237 432 8.38E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 Gene3D G3DSA:3.40.50.300 549 711 9.7E-4 T 29-03-2018 HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 14 208 5.6E-17 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 SUPERFAMILY SSF52540 617 734 2.39E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 SUPERFAMILY SSF52540 300 361 2.39E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06600 5b5413d8baaaa03af22c3be8cc044060 996 SMART SM00487 275 503 1.6E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS06320 792355ab1ddcf1ae8567ba64546d83ba 212 SUPERFAMILY SSF53335 29 212 3.32E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS06320 792355ab1ddcf1ae8567ba64546d83ba 212 Gene3D G3DSA:3.40.50.150 4 212 1.2E-37 T 29-03-2018 HVS_RS06320 792355ab1ddcf1ae8567ba64546d83ba 212 Pfam PF01596 O-methyltransferase 37 211 4.7E-33 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 HVS_RS04355 1dcaae157028da9ff683ed533aefe776 96 Pfam PF04456 Protein of unknown function (DUF503) 3 89 5.7E-33 T 29-03-2018 IPR007546 Protein of unknown function DUF503 HVS_RS04355 1dcaae157028da9ff683ed533aefe776 96 SUPERFAMILY SSF103007 1 94 1.83E-30 T 29-03-2018 IPR007546 Protein of unknown function DUF503 HVS_RS04355 1dcaae157028da9ff683ed533aefe776 96 Gene3D G3DSA:3.30.70.1120 2 92 3.3E-32 T 29-03-2018 HVS_RS03830 bef1f090b42853f2d6552ec7a2269172 196 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 70 94 7.4E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS03830 bef1f090b42853f2d6552ec7a2269172 196 Gene3D G3DSA:2.170.16.10 3 17 0.17 T 29-03-2018 HVS_RS03830 bef1f090b42853f2d6552ec7a2269172 196 SUPERFAMILY SSF51294 13 94 1.75E-17 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03830 bef1f090b42853f2d6552ec7a2269172 196 Pfam PF07591 Pretoxin HINT domain 21 94 9.5E-18 T 29-03-2018 HVS_RS03830 bef1f090b42853f2d6552ec7a2269172 196 Gene3D G3DSA:2.170.16.10 18 95 5.0E-19 T 29-03-2018 HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 Gene3D G3DSA:2.60.120.260 30 203 4.5E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 SMART SM00327 496 739 0.0024 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 Pfam PF00092 von Willebrand factor type A domain 547 748 6.9E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 SUPERFAMILY SSF53300 546 647 3.02E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 SUPERFAMILY SSF53300 678 750 3.02E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 SUPERFAMILY SSF49785 38 192 2.27E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 Pfam PF02018 Carbohydrate binding domain 40 172 1.8E-15 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS10695 f8017e51575ee1a1c52d017bd42aa61e 877 Gene3D G3DSA:3.40.50.410 263 759 2.6E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 41.452 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 Gene3D G3DSA:3.40.50.620 1 174 2.8E-83 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 2.3E-114 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 SUPERFAMILY SSF52374 1 279 8.0E-112 T 29-03-2018 HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 Gene3D G3DSA:3.30.1300.10 175 281 2.2E-32 T 29-03-2018 HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 74 1.6E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HVS_RS09315 0a5bba0c08a1412def0da7c5df93ee48 281 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 2.9E-111 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 145 2.6E-48 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 Gene3D G3DSA:3.40.50.720 8 147 4.4E-42 T 29-03-2018 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 SUPERFAMILY SSF56327 146 314 1.05E-57 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 315 44.35 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 313 2.4E-36 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 SUPERFAMILY SSF51735 5 145 1.98E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 Gene3D G3DSA:3.90.110.10 148 316 1.5E-49 T 29-03-2018 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 PIRSF PIRSF000102 4 316 1.2E-114 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.2E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 1.2E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 1.2E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 1.2E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 1.2E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 309 3.9E-130 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 HVS_RS07495 abe22f110bbad88d6566e04ab236be3f 316 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 HVS_RS07115 10e7e105599889e6b40c78e1891cd063 442 Gene3D G3DSA:2.40.50.140 377 442 9.5E-11 T 29-03-2018 HVS_RS07115 10e7e105599889e6b40c78e1891cd063 442 Gene3D G3DSA:3.90.226.10 26 222 2.5E-24 T 29-03-2018 HVS_RS07115 10e7e105599889e6b40c78e1891cd063 442 Pfam PF01957 NfeD-like C-terminal, partner-binding 290 440 1.1E-20 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain HVS_RS07115 10e7e105599889e6b40c78e1891cd063 442 SUPERFAMILY SSF141322 378 438 5.23E-6 T 29-03-2018 HVS_RS07115 10e7e105599889e6b40c78e1891cd063 442 SUPERFAMILY SSF52096 18 204 2.26E-24 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS07115 10e7e105599889e6b40c78e1891cd063 442 Pfam PF01972 Serine dehydrogenase proteinase 59 156 4.5E-7 T 29-03-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 HVS_RS05995 7a60c35eca84ac820c9a2169b0e62d6a 124 Pfam PF03646 FlaG protein 29 122 8.5E-29 T 29-03-2018 IPR005186 FlaG protein HVS_RS05995 7a60c35eca84ac820c9a2169b0e62d6a 124 Gene3D G3DSA:3.30.160.170 10 120 9.1E-28 T 29-03-2018 IPR005186 FlaG protein HVS_RS05995 7a60c35eca84ac820c9a2169b0e62d6a 124 SUPERFAMILY SSF160214 32 123 1.83E-26 T 29-03-2018 IPR005186 FlaG protein HVS_RS14830 7a60c35eca84ac820c9a2169b0e62d6a 124 Pfam PF03646 FlaG protein 29 122 8.5E-29 T 29-03-2018 IPR005186 FlaG protein HVS_RS14830 7a60c35eca84ac820c9a2169b0e62d6a 124 Gene3D G3DSA:3.30.160.170 10 120 9.1E-28 T 29-03-2018 IPR005186 FlaG protein HVS_RS14830 7a60c35eca84ac820c9a2169b0e62d6a 124 SUPERFAMILY SSF160214 32 123 1.83E-26 T 29-03-2018 IPR005186 FlaG protein HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 SUPERFAMILY SSF54211 349 533 4.55E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 Gene3D G3DSA:3.40.50.300 46 254 9.6E-32 T 29-03-2018 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 92 264 8.7E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 533 3.2E-271 T 29-03-2018 IPR014251 Sporulation protease LonB HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 172 187 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 Gene3D G3DSA:1.10.8.60 255 327 1.2E-8 T 29-03-2018 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 443 451 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 493 511 4.3E-30 T 29-03-2018 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 470 489 4.3E-30 T 29-03-2018 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 96 115 4.3E-30 T 29-03-2018 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 440 459 4.3E-30 T 29-03-2018 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 SMART SM00382 88 266 3.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 343 531 1.4E-32 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 SUPERFAMILY SSF52540 234 327 1.73E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 SUPERFAMILY SSF52540 54 203 1.73E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12865 ce1b3aca447c325345414146c8db763d 559 Gene3D G3DSA:3.30.230.10 328 552 8.2E-55 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS04420 a5a924dec12f4171696b661a145aff7a 203 Gene3D G3DSA:3.40.630.30 44 180 8.1E-15 T 29-03-2018 HVS_RS04420 a5a924dec12f4171696b661a145aff7a 203 TIGRFAM TIGR03585 PseH: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase 15 167 2.0E-32 T 29-03-2018 IPR020036 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase HVS_RS04420 a5a924dec12f4171696b661a145aff7a 203 SUPERFAMILY SSF55729 24 171 5.99E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS04420 a5a924dec12f4171696b661a145aff7a 203 Pfam PF13302 Acetyltransferase (GNAT) domain 30 147 1.2E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS03145 05c1716947653130d52db556c3e92f71 423 Gene3D G3DSA:3.40.50.410 151 311 4.5E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS03145 05c1716947653130d52db556c3e92f71 423 SUPERFAMILY SSF53300 151 324 1.53E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS03145 05c1716947653130d52db556c3e92f71 423 Pfam PF00092 von Willebrand factor type A domain 153 295 2.4E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS03145 05c1716947653130d52db556c3e92f71 423 SMART SM00327 151 330 2.3E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 8.0E-26 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 8.0E-26 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 8.0E-26 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 8.0E-26 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 Gene3D G3DSA:2.30.330.10 238 330 2.4E-21 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 Gene3D G3DSA:3.40.1550.10 47 236 1.8E-45 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 SUPERFAMILY SSF103039 45 230 3.4E-24 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 323 5.0E-100 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 323 5.2E-23 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 Pfam PF02154 Flagellar motor switch protein FliM 39 229 2.4E-64 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 SUPERFAMILY SSF101801 250 327 5.1E-19 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) HVS_RS10200 1979dbd4f5e03bfdba92a1ef2341eba4 331 PIRSF PIRSF002888 2 330 1.5E-108 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 HVS_RS15930 2584da4689d80ba040edf1570c6d18b6 153 Gene3D G3DSA:2.30.30.110 32 153 7.5E-25 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS15930 2584da4689d80ba040edf1570c6d18b6 153 SUPERFAMILY SSF50118 33 153 2.4E-18 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS15930 2584da4689d80ba040edf1570c6d18b6 153 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 34 150 3.0E-21 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HVS_RS14340 9a5bf1eb74b00a0bed6cb299a46dee8c 294 PIRSF PIRSF003097 2 294 1.0E-74 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 HVS_RS14340 9a5bf1eb74b00a0bed6cb299a46dee8c 294 Pfam PF02687 FtsX-like permease family 199 293 2.8E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS12690 d77c8e64f8700cd70e5965c94829ffe5 240 SUPERFAMILY SSF53187 46 238 3.11E-48 T 29-03-2018 HVS_RS12690 d77c8e64f8700cd70e5965c94829ffe5 240 SMART SM00646 121 234 3.6E-18 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HVS_RS12690 d77c8e64f8700cd70e5965c94829ffe5 240 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 46 236 5.0E-70 T 29-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD HVS_RS12690 d77c8e64f8700cd70e5965c94829ffe5 240 Gene3D G3DSA:3.40.630.40 42 240 2.7E-54 T 29-03-2018 HVS_RS12690 d77c8e64f8700cd70e5965c94829ffe5 240 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 47 234 2.1E-49 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HVS_RS04220 004330af3d97dd675ba72079ccc1e1ec 549 Pfam PF13817 IS66 C-terminal element 496 536 3.5E-8 T 29-03-2018 HVS_RS04220 004330af3d97dd675ba72079ccc1e1ec 549 Pfam PF03050 Transposase IS66 family 199 489 1.8E-83 T 29-03-2018 IPR004291 Transposase, IS66 HVS_RS04220 004330af3d97dd675ba72079ccc1e1ec 549 Pfam PF13005 zinc-finger binding domain of transposase IS66 135 178 2.3E-12 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 HVS_RS04220 004330af3d97dd675ba72079ccc1e1ec 549 Pfam PF13007 Transposase C of IS166 homeodomain 56 127 3.3E-5 T 29-03-2018 IPR024463 Transposase TnpC, homeodomain HVS_RS06255 fdfaadb9ea6b8af36632d95bcc486681 203 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 69 2.8E-12 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HVS_RS06255 fdfaadb9ea6b8af36632d95bcc486681 203 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 4 203 31.77 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HVS_RS06255 fdfaadb9ea6b8af36632d95bcc486681 203 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 8 202 5.2E-56 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HVS_RS06255 fdfaadb9ea6b8af36632d95bcc486681 203 Pfam PF01467 Cytidylyltransferase-like 8 177 9.9E-32 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HVS_RS06255 fdfaadb9ea6b8af36632d95bcc486681 203 SUPERFAMILY SSF52374 4 202 1.09E-56 T 29-03-2018 HVS_RS06255 fdfaadb9ea6b8af36632d95bcc486681 203 Gene3D G3DSA:3.40.50.620 2 203 5.5E-57 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS02925 62de163e218633847f279b23473a81af 269 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 162 242 4.0E-23 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS12185 fb3c28dde2305674cee8d714a858b684 351 Pfam PF03186 CobD/Cbib protein 10 325 7.0E-90 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 HVS_RS12185 fb3c28dde2305674cee8d714a858b684 351 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 346 78.075 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 HVS_RS12185 fb3c28dde2305674cee8d714a858b684 351 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 11 343 4.2E-63 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 Pfam PF07508 Recombinase 196 318 3.3E-19 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 Gene3D G3DSA:1.10.1660.10 182 491 0.032 T 29-03-2018 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 Pfam PF14287 Domain of unknown function (DUF4368) 482 547 1.3E-25 T 29-03-2018 IPR025378 Domain of unknown function DUF4368 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 Gene3D G3DSA:3.40.50.1390 17 181 8.9E-43 T 29-03-2018 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 SMART SM00857 23 173 1.0E-39 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 Pfam PF00239 Resolvase, N terminal domain 24 172 1.7E-22 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 SUPERFAMILY SSF53041 23 172 1.31E-30 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS15900 227d0dcb8c76afed56d01d05b2c65cb2 550 Pfam PF13408 Recombinase zinc beta ribbon domain 330 389 3.5E-14 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain HVS_RS02770 78cd9dbb34762db05f638ba23693321e 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.076 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid HVS_RS02770 78cd9dbb34762db05f638ba23693321e 130 SUPERFAMILY SSF54211 6 130 8.34E-51 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS02770 78cd9dbb34762db05f638ba23693321e 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.1E-48 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HVS_RS02770 78cd9dbb34762db05f638ba23693321e 130 Gene3D G3DSA:3.30.230.10 3 130 2.4E-54 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS02770 78cd9dbb34762db05f638ba23693321e 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 HVS_RS09210 92292c1f802907c1e07c7caf18722ebe 93 Gene3D G3DSA:3.40.1690.10 7 86 1.3E-26 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HVS_RS09210 92292c1f802907c1e07c7caf18722ebe 93 Pfam PF01312 FlhB HrpN YscU SpaS Family 12 82 2.9E-19 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 HVS_RS09210 92292c1f802907c1e07c7caf18722ebe 93 SUPERFAMILY SSF160544 9 86 4.58E-22 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal HVS_RS09915 7fd53bd1a0cfdf29bf7e67ed2f68ed16 143 SUPERFAMILY SSF55021 3 67 1.69E-17 T 29-03-2018 HVS_RS09915 7fd53bd1a0cfdf29bf7e67ed2f68ed16 143 Gene3D G3DSA:3.30.2130.10 73 143 1.8E-7 T 29-03-2018 HVS_RS09915 7fd53bd1a0cfdf29bf7e67ed2f68ed16 143 Gene3D G3DSA:3.30.2130.10 3 72 7.5E-12 T 29-03-2018 HVS_RS09915 7fd53bd1a0cfdf29bf7e67ed2f68ed16 143 Pfam PF01842 ACT domain 5 61 1.9E-8 T 29-03-2018 IPR002912 ACT domain HVS_RS09915 7fd53bd1a0cfdf29bf7e67ed2f68ed16 143 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 6 61 0.004 T 29-03-2018 HVS_RS09915 7fd53bd1a0cfdf29bf7e67ed2f68ed16 143 SUPERFAMILY SSF55021 71 143 2.21E-13 T 29-03-2018 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 Pfam PF01872 RibD C-terminal domain 148 357 1.7E-52 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 PIRSF PIRSF006769 1 364 2.4E-141 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 SUPERFAMILY SSF53927 4 142 2.01E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 101 1.7E-23 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 Gene3D G3DSA:3.40.430.10 126 364 3.4E-72 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 360 2.1E-69 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 357 1.3E-117 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 Gene3D G3DSA:3.40.140.10 1 125 3.4E-37 T 29-03-2018 HVS_RS05435 b43328fe19e4bf4bdfbdb815c9f82d55 364 SUPERFAMILY SSF53597 148 361 1.03E-61 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 HVS_RS02450 482e72bea094e4997d47947e84210f26 768 SMART SM00843 696 761 1.7E-34 T 29-03-2018 IPR018541 FtsK gamma domain HVS_RS02450 482e72bea094e4997d47947e84210f26 768 Pfam PF01580 FtsK/SpoIIIE family 545 596 4.1E-15 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HVS_RS02450 482e72bea094e4997d47947e84210f26 768 Pfam PF01580 FtsK/SpoIIIE family 406 540 7.5E-46 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HVS_RS02450 482e72bea094e4997d47947e84210f26 768 SUPERFAMILY SSF52540 379 668 5.18E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02450 482e72bea094e4997d47947e84210f26 768 SUPERFAMILY SSF46785 696 763 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02450 482e72bea094e4997d47947e84210f26 768 Gene3D G3DSA:3.40.50.300 4 639 4.6E-56 T 29-03-2018 HVS_RS02450 482e72bea094e4997d47947e84210f26 768 Gene3D G3DSA:1.10.10.10 699 752 4.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02450 482e72bea094e4997d47947e84210f26 768 Pfam PF09397 Ftsk gamma domain 699 759 1.2E-26 T 29-03-2018 IPR018541 FtsK gamma domain HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 Pfam PF02195 ParB-like nuclease domain 5 92 2.0E-10 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 PIRSF PIRSF036758 1 432 1.7E-95 T 29-03-2018 IPR015840 DNA methyase, ParB domain-containing HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 Gene3D G3DSA:3.40.50.150 169 431 3.9E-37 T 29-03-2018 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 SUPERFAMILY SSF53335 161 425 2.29E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 Pfam PF01555 DNA methylase 194 417 1.7E-27 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 Gene3D G3DSA:3.90.1530.10 1 97 1.1E-14 T 29-03-2018 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 377 395 6.7E-17 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 358 375 6.7E-17 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 192 206 6.7E-17 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 400 420 6.7E-17 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 SUPERFAMILY SSF110849 4 93 1.6E-14 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS13245 1e2832ddedfe558daf6067461e83c035 432 SMART SM00470 4 93 1.1E-7 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS05230 f7b7f940e7916c126cde9db84d702e78 333 Gene3D G3DSA:3.40.718.10 1 333 5.3E-147 T 29-03-2018 HVS_RS05230 f7b7f940e7916c126cde9db84d702e78 333 SUPERFAMILY SSF53659 2 331 6.53E-135 T 29-03-2018 HVS_RS05230 f7b7f940e7916c126cde9db84d702e78 333 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 327 1.6E-110 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS05230 f7b7f940e7916c126cde9db84d702e78 333 SMART SM01329 3 327 9.6E-192 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS05230 f7b7f940e7916c126cde9db84d702e78 333 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 223 242 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 PIRSF PIRSF001365 1 291 6.3E-90 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 5 288 63.258 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 166 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 3.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 3.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 3.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 3.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 SMART SM01130 5 290 6.8E-134 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 10 288 2.6E-105 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 Pfam PF00701 Dihydrodipicolinate synthetase family 6 286 6.2E-98 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 SUPERFAMILY SSF51569 4 290 1.15E-97 T 29-03-2018 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08990 9d63226062702ac5932998140d033c7a 292 Gene3D G3DSA:3.20.20.70 1 292 1.1E-95 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS01890 b5425ebd86ca38ffa81d1d27436ebcb1 491 Pfam PF06782 Uncharacterised protein family (UPF0236) 8 418 1.8E-53 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS01915 b5425ebd86ca38ffa81d1d27436ebcb1 491 Pfam PF06782 Uncharacterised protein family (UPF0236) 8 418 1.8E-53 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS11225 762cbb0140b8b913ceaa47fd16082fd2 290 Pfam PF10728 Domain of unknown function (DUF2520) 136 265 3.0E-34 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 HVS_RS11225 762cbb0140b8b913ceaa47fd16082fd2 290 SUPERFAMILY SSF48179 169 272 3.37E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS11225 762cbb0140b8b913ceaa47fd16082fd2 290 Gene3D G3DSA:1.10.1040.20 169 269 3.9E-24 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 HVS_RS11225 762cbb0140b8b913ceaa47fd16082fd2 290 Pfam PF10727 Rossmann-like domain 2 119 6.1E-14 T 29-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain HVS_RS11225 762cbb0140b8b913ceaa47fd16082fd2 290 Gene3D G3DSA:3.40.50.720 1 167 1.1E-14 T 29-03-2018 HVS_RS11225 762cbb0140b8b913ceaa47fd16082fd2 290 SUPERFAMILY SSF51735 2 167 3.48E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS07255 2679607814857891bc931a0e6927d187 327 Gene3D G3DSA:3.40.718.10 19 302 7.9E-63 T 29-03-2018 HVS_RS07255 2679607814857891bc931a0e6927d187 327 PIRSF PIRSF000428 1 327 2.8E-112 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HVS_RS07255 2679607814857891bc931a0e6927d187 327 SUPERFAMILY SSF53659 1 327 2.75E-100 T 29-03-2018 HVS_RS07255 2679607814857891bc931a0e6927d187 327 Pfam PF01515 Phosphate acetyl/butaryl transferase 2 324 1.3E-133 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HVS_RS07255 2679607814857891bc931a0e6927d187 327 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 324 2.4E-118 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 Gene3D G3DSA:3.10.290.10 1 60 3.4E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 223 2.0E-51 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 SMART SM00363 1 59 3.3E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 SUPERFAMILY SSF55120 56 230 1.82E-48 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 Gene3D G3DSA:3.30.2350.10 61 232 5.2E-48 T 29-03-2018 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 Pfam PF00849 RNA pseudouridylate synthase 62 192 6.3E-23 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 SUPERFAMILY SSF55174 1 65 6.08E-17 T 29-03-2018 HVS_RS08215 f99e5f5702fbd20dc679a0d573d5cd82 232 Pfam PF01479 S4 domain 2 47 1.8E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS14620 73203da3a07d27d27e0008b4b447d8bc 249 Pfam PF05175 Methyltransferase small domain 38 174 4.0E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 HVS_RS14620 73203da3a07d27d27e0008b4b447d8bc 249 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 123 129 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS14620 73203da3a07d27d27e0008b4b447d8bc 249 Gene3D G3DSA:3.40.50.150 34 217 8.5E-40 T 29-03-2018 HVS_RS14620 73203da3a07d27d27e0008b4b447d8bc 249 SUPERFAMILY SSF53335 13 217 8.74E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 SUPERFAMILY SSF142984 350 433 1.22E-25 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 157 328 1.5E-47 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Gene3D G3DSA:3.30.70.20 420 551 3.6E-8 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Pfam PF00037 4Fe-4S binding domain 540 563 9.8E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Pfam PF00037 4Fe-4S binding domain 572 594 8.9E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 SUPERFAMILY SSF52833 4 95 4.14E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 SUPERFAMILY SSF142019 109 349 1.16E-96 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 5 81 9.6E-9 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Gene3D G3DSA:3.40.30.10 3 103 6.6E-27 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 451 462 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 SMART SM00928 438 483 1.6E-25 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 SUPERFAMILY SSF140490 434 536 6.54E-40 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 439 523 1.5E-33 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 SUPERFAMILY SSF54862 540 595 4.19E-16 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Pfam PF10531 SLBB domain 352 400 1.0E-6 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 Gene3D G3DSA:3.30.70.20 552 597 1.4E-14 T 29-03-2018 HVS_RS12380 87a3091f1f1e97ffd362085f1b4e85a2 598 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 579 590 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS02295 adfa1ff8cb3aed3846a50e96fe7aee40 562 Pfam PF13416 Bacterial extracellular solute-binding protein 70 384 6.0E-15 T 29-03-2018 HVS_RS02295 adfa1ff8cb3aed3846a50e96fe7aee40 562 SUPERFAMILY SSF53850 46 431 3.8E-70 T 29-03-2018 HVS_RS02295 adfa1ff8cb3aed3846a50e96fe7aee40 562 SUPERFAMILY SSF53850 475 555 3.8E-70 T 29-03-2018 HVS_RS02295 adfa1ff8cb3aed3846a50e96fe7aee40 562 Gene3D G3DSA:3.40.190.10 182 557 6.5E-31 T 29-03-2018 HVS_RS02295 adfa1ff8cb3aed3846a50e96fe7aee40 562 Gene3D G3DSA:3.40.190.10 48 181 6.1E-10 T 29-03-2018 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PIRSF PIRSF001415 4 330 1.8E-139 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 301 320 1.0E-52 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 126 140 1.0E-52 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 194 213 1.0E-52 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 156 175 1.0E-52 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 271 286 1.0E-52 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 246 262 1.0E-52 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 324 4.0E-143 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 SUPERFAMILY SSF51569 11 328 2.78E-133 T 29-03-2018 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 SMART SM01004 8 327 1.8E-205 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 246 258 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 HVS_RS02620 f1d8faaaa441cda96958a897fd14533c 333 Gene3D G3DSA:3.20.20.70 3 331 3.1E-144 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS01515 914e562b9c2c379de9a6fd0a07d7869e 252 Gene3D G3DSA:3.40.50.300 40 235 1.0E-14 T 29-03-2018 HVS_RS01515 914e562b9c2c379de9a6fd0a07d7869e 252 Pfam PF01695 IstB-like ATP binding protein 56 231 6.2E-59 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS01515 914e562b9c2c379de9a6fd0a07d7869e 252 PIRSF PIRSF003073 1 251 1.0E-81 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS01515 914e562b9c2c379de9a6fd0a07d7869e 252 SMART SM00382 100 235 4.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01515 914e562b9c2c379de9a6fd0a07d7869e 252 SUPERFAMILY SSF52540 67 240 6.29E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 ProSitePatterns PS00018 EF-hand calcium-binding domain. 928 940 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 SUPERFAMILY SSF54001 100 370 8.77E-16 T 29-03-2018 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Gene3D G3DSA:3.90.70.10 57 388 1.3E-22 T 29-03-2018 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Gene3D G3DSA:2.120.10.80 744 924 8.3E-14 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Pfam PF00404 Dockerin type I repeat 928 948 1.3E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Pfam PF00404 Dockerin type I repeat 964 984 4.9E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Gene3D G3DSA:2.130.10.80 512 718 3.1E-7 T 29-03-2018 IPR015916 Galactose oxidase, beta-propeller HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Pfam PF01344 Kelch motif 561 603 2.5E-9 T 29-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 Gene3D G3DSA:1.10.1330.10 925 990 3.2E-4 T 29-03-2018 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 SUPERFAMILY SSF63446 924 988 7.46E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 SUPERFAMILY SSF50965 562 629 1.31E-18 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 SUPERFAMILY SSF50965 681 709 1.31E-18 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller HVS_RS09760 177cb5ffbb84c9458a4d78bd36ff1276 990 SUPERFAMILY SSF50965 771 901 1.31E-18 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 Gene3D G3DSA:3.90.1150.10 293 429 6.8E-50 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 425 2.9E-147 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 Gene3D G3DSA:3.40.640.10 6 291 4.2E-66 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 SUPERFAMILY SSF53383 7 425 4.47E-135 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 425 1.2E-209 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 HVS_RS02335 fed1b606d5dee651dc9558ff3874c2ea 429 PIRSF PIRSF001434 1 428 8.0E-131 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HVS_RS14730 8484d847179888aeacf9639acd92d151 278 Gene3D G3DSA:3.60.140.10 13 278 1.5E-82 T 29-03-2018 HVS_RS14730 8484d847179888aeacf9639acd92d151 278 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 44 277 5.5E-56 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase HVS_RS14730 8484d847179888aeacf9639acd92d151 278 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 39 275 1.4E-77 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase HVS_RS14730 8484d847179888aeacf9639acd92d151 278 SUPERFAMILY SSF64438 31 277 5.86E-79 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic HVS_RS06095 8484d847179888aeacf9639acd92d151 278 Gene3D G3DSA:3.60.140.10 13 278 1.5E-82 T 29-03-2018 HVS_RS06095 8484d847179888aeacf9639acd92d151 278 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 44 277 5.5E-56 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase HVS_RS06095 8484d847179888aeacf9639acd92d151 278 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 39 275 1.4E-77 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase HVS_RS06095 8484d847179888aeacf9639acd92d151 278 SUPERFAMILY SSF64438 31 277 5.86E-79 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 Gene3D G3DSA:3.20.20.70 10 339 3.0E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 SMART SM01091 339 415 8.6E-21 T 29-03-2018 IPR005170 Transporter-associated domain HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 Gene3D G3DSA:3.30.465.10 340 415 5.0E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 SUPERFAMILY SSF56176 337 414 3.54E-20 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 Pfam PF00571 CBS domain 276 324 1.1E-5 T 29-03-2018 IPR000644 CBS domain HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 Pfam PF00571 CBS domain 206 259 1.1E-5 T 29-03-2018 IPR000644 CBS domain HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 Pfam PF03471 Transporter associated domain 340 414 1.5E-20 T 29-03-2018 IPR005170 Transporter-associated domain HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 SUPERFAMILY SSF54631 199 341 8.46E-33 T 29-03-2018 HVS_RS02870 681c5f7afad967a406a2a37761d5c3f0 415 Pfam PF01595 Domain of unknown function DUF21 12 189 2.5E-55 T 29-03-2018 IPR002550 Domain of unknown function DUF21 HVS_RS04385 26079720ccbcbe51c5ca53acff5a0d3b 71 Gene3D G3DSA:1.10.1200.10 2 71 6.1E-8 T 29-03-2018 HVS_RS04385 26079720ccbcbe51c5ca53acff5a0d3b 71 Pfam PF00550 Phosphopantetheine attachment site 5 70 1.1E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS04385 26079720ccbcbe51c5ca53acff5a0d3b 71 SUPERFAMILY SSF47336 5 70 3.14E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SUPERFAMILY SSF48452 172 519 9.48E-44 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.20.120.420 69 119 5.0E-14 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SUPERFAMILY SSF48452 31 166 2.66E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF07719 Tetratricopeptide repeat 65 96 1.4E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF07719 Tetratricopeptide repeat 31 62 2.3E-7 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 98 131 23.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 489 522 9.3E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 30 63 5.9E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 384 417 9.0E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 276 309 210.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 344 377 0.023 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 455 488 6.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 132 165 0.24 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 237 270 0.13 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 64 97 1.7E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 169 202 5.2E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 310 343 0.014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 421 454 0.019 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 SMART SM00028 203 236 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF13181 Tetratricopeptide repeat 239 267 0.005 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 271 328 8.0E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 120 185 2.0E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.10.287.1110 186 198 3.1E-8 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.10.287.1110 329 344 1.7E-6 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF00515 Tetratricopeptide repeat 170 201 8.3E-7 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 431 465 1.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 30 68 2.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.20.58.280 466 484 7.3E-5 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF13432 Tetratricopeptide repeat 114 164 0.01 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF13432 Tetratricopeptide repeat 390 449 2.8E-4 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF13432 Tetratricopeptide repeat 319 374 7.1E-4 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Pfam PF13432 Tetratricopeptide repeat 461 517 9.3E-5 T 29-03-2018 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 485 548 3.2E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 199 269 3.9E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.25.40.10 392 430 1.7E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14455 86b9c7ebab6a03c3475be84a84fdc284 573 Gene3D G3DSA:1.10.150.200 345 391 2.6E-10 T 29-03-2018 HVS_RS11080 b6781a4cdcb5ef8b4c79ca18228f186a 292 Pfam PF08340 Domain of unknown function (DUF1732) 209 292 4.4E-36 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 HVS_RS11080 b6781a4cdcb5ef8b4c79ca18228f186a 292 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 292 9.6E-78 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 HVS_RS11080 b6781a4cdcb5ef8b4c79ca18228f186a 292 Pfam PF03755 YicC-like family, N-terminal region 2 156 2.0E-43 T 29-03-2018 IPR013527 YicC-like, N-terminal HVS_RS08375 bb4ca7806ab904ab4a28201d7fcca458 80 Pfam PF00886 Ribosomal protein S16 9 67 1.4E-27 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS08375 bb4ca7806ab904ab4a28201d7fcca458 80 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 78 1.8E-36 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS08375 bb4ca7806ab904ab4a28201d7fcca458 80 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 26.248 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS08375 bb4ca7806ab904ab4a28201d7fcca458 80 Gene3D G3DSA:3.30.1320.10 2 79 4.1E-34 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS08375 bb4ca7806ab904ab4a28201d7fcca458 80 SUPERFAMILY SSF54565 2 77 2.75E-34 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS09990 eb96286e897c79e7f63d5f0a95e283d3 202 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 7.1E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS09990 eb96286e897c79e7f63d5f0a95e283d3 202 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS09990 eb96286e897c79e7f63d5f0a95e283d3 202 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 31 6.2E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS09990 eb96286e897c79e7f63d5f0a95e283d3 202 Gene3D G3DSA:3.30.700.10 11 191 1.7E-15 T 29-03-2018 HVS_RS09990 eb96286e897c79e7f63d5f0a95e283d3 202 SUPERFAMILY SSF54523 11 79 6.12E-13 T 29-03-2018 HVS_RS05040 dc4bb5ad39edd9577d7474021983cf8b 286 Gene3D G3DSA:3.30.240.20 82 151 1.3E-21 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain HVS_RS05040 dc4bb5ad39edd9577d7474021983cf8b 286 Pfam PF07870 Protein of unknown function (DUF1657) 237 284 1.4E-16 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 HVS_RS05040 dc4bb5ad39edd9577d7474021983cf8b 286 Pfam PF04239 Protein of unknown function (DUF421) 89 204 1.0E-29 T 29-03-2018 IPR007353 Protein of unknown function DUF421 HVS_RS05040 dc4bb5ad39edd9577d7474021983cf8b 286 Gene3D G3DSA:3.30.240.20 171 225 4.1E-11 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 279 365 3.2E-15 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 Gene3D G3DSA:3.40.710.10 27 278 6.7E-60 T 29-03-2018 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 SMART SM00936 276 366 7.6E-12 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 SUPERFAMILY SSF56601 36 276 1.83E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 36 255 1.7E-71 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 117 134 5.4E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 69 80 5.4E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 5.4E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 Gene3D G3DSA:2.60.410.10 279 366 4.5E-14 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05870 edd5ade6bc5d646dc35a9f822c263589 387 SUPERFAMILY SSF69189 268 364 7.46E-16 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05920 58343754c00f364a01571cfb6625f44b 177 Pfam PF05239 PRC-barrel domain 92 156 3.4E-8 T 29-03-2018 IPR027275 PRC-barrel domain HVS_RS05920 58343754c00f364a01571cfb6625f44b 177 Pfam PF05239 PRC-barrel domain 2 70 9.3E-8 T 29-03-2018 IPR027275 PRC-barrel domain HVS_RS05920 58343754c00f364a01571cfb6625f44b 177 Gene3D G3DSA:2.30.30.240 1 66 1.8E-8 T 29-03-2018 HVS_RS05920 58343754c00f364a01571cfb6625f44b 177 SUPERFAMILY SSF50346 90 142 1.57E-8 T 29-03-2018 IPR011033 PRC-barrel-like HVS_RS05920 58343754c00f364a01571cfb6625f44b 177 Gene3D G3DSA:3.90.50.10 67 168 2.0E-7 T 29-03-2018 HVS_RS05920 58343754c00f364a01571cfb6625f44b 177 SUPERFAMILY SSF50346 2 70 8.01E-9 T 29-03-2018 IPR011033 PRC-barrel-like HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 357 2.1E-136 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 PIRSF PIRSF004640 1 362 1.8E-153 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 SUPERFAMILY SSF51717 16 208 1.18E-12 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 362 36.299 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 SUPERFAMILY SSF56014 266 358 1.57E-12 T 29-03-2018 HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 Gene3D G3DSA:3.20.20.120 16 226 3.0E-24 T 29-03-2018 IPR029065 Enolase C-terminal domain-like HVS_RS06385 be60743ef50d12e024625abfd80f2df2 363 Pfam PF04551 GcpE protein 12 358 1.5E-145 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 HVS_RS07390 2000b9240fef63ce0c7732b2aec1cd4d 102 Pfam PF07873 YabP family 38 100 3.4E-17 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC HVS_RS07390 2000b9240fef63ce0c7732b2aec1cd4d 102 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 19 101 3.0E-23 T 29-03-2018 IPR022477 Sporulation protein YqfC HVS_RS14265 d9a79bd51a6cf58d479cc044898104e3 360 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 103 125 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site HVS_RS14265 d9a79bd51a6cf58d479cc044898104e3 360 SUPERFAMILY SSF53850 55 353 4.05E-71 T 29-03-2018 HVS_RS14265 d9a79bd51a6cf58d479cc044898104e3 360 Gene3D G3DSA:3.40.190.10 225 357 1.1E-29 T 29-03-2018 HVS_RS14265 d9a79bd51a6cf58d479cc044898104e3 360 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 353 8.3E-51 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain HVS_RS14265 d9a79bd51a6cf58d479cc044898104e3 360 Gene3D G3DSA:3.90.76.10 64 224 7.0E-33 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 200 333 1.49E-29 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 1540 1677 1.31E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49464 2032 2120 7.45E-15 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 368 501 1.49E-29 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 882 1020 2.25E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 34 176 1.4E-24 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 1707 1847 2.1E-25 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 1044 1184 2.6E-25 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 364 502 6.7E-25 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 727 868 1.6E-26 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 1538 1678 2.1E-25 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 1882 2022 3.6E-26 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 880 1021 3.1E-25 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 1369 1509 9.9E-26 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 196 334 6.7E-25 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 1709 1846 1.31E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 531 688 2.41E-53 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00942 Cellulose binding domain 536 624 4.4E-23 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 1371 1508 8.64E-32 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.680 1205 1349 3.7E-24 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF63446 2118 2178 5.49E-8 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 ProSitePatterns PS00018 EF-hand calcium-binding domain. 2157 2169 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.1120 2029 2125 6.9E-9 T 29-03-2018 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 39 175 1.39E-28 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 1209 1343 8.37E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 729 867 1.91E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 1046 1183 2.15E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Gene3D G3DSA:2.60.40.710 522 697 2.8E-51 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SUPERFAMILY SSF49384 1885 2021 5.76E-32 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 SMART SM01067 536 625 6.8E-33 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 367 500 8.8E-27 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 1541 1677 4.7E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 731 867 1.9E-27 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 1885 2021 3.9E-29 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 199 332 8.8E-27 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 40 174 2.4E-25 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 1710 1846 4.7E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 883 1018 4.8E-27 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 1372 1508 4.7E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 1210 1345 7.4E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02495 94aa8af07b5ee6bdb0a0c0e3b553aab8 2185 Pfam PF00963 Cohesin domain 1047 1182 1.3E-27 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS14030 3228bb65cc639ca3c60e8fd19b697d6c 528 Pfam PF04932 O-Antigen ligase 318 450 6.3E-22 T 29-03-2018 IPR007016 O-antigen ligase-related HVS_RS02655 ca9d3bbbb202cdfdfd2e6de818f84639 137 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 110 1.5E-22 T 29-03-2018 IPR028090 JAB domain, prokaryotic HVS_RS02655 ca9d3bbbb202cdfdfd2e6de818f84639 137 SUPERFAMILY SSF102712 2 132 6.28E-29 T 29-03-2018 HVS_RS02655 ca9d3bbbb202cdfdfd2e6de818f84639 137 Gene3D G3DSA:3.40.140.10 1 137 5.1E-26 T 29-03-2018 HVS_RS02655 ca9d3bbbb202cdfdfd2e6de818f84639 137 SMART SM00232 1 133 6.2E-11 T 29-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 HVS_RS09280 3549de79556b72c0cb6fa60ac8973f26 74 SUPERFAMILY SSF47240 6 68 5.13E-9 T 29-03-2018 IPR009078 Ferritin-like superfamily HVS_RS09280 3549de79556b72c0cb6fa60ac8973f26 74 Pfam PF02915 Rubrerythrin 26 69 4.9E-6 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HVS_RS09280 3549de79556b72c0cb6fa60ac8973f26 74 Gene3D G3DSA:1.20.1260.10 4 73 3.5E-8 T 29-03-2018 IPR012347 Ferritin-related HVS_RS03745 a12a7eccea930255859235a0e46721a8 112 SUPERFAMILY SSF103481 39 111 1.44E-12 T 29-03-2018 HVS_RS03745 a12a7eccea930255859235a0e46721a8 112 Pfam PF00892 EamA-like transporter family 44 111 1.4E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HVS_RS07785 57985a1f5343d6cda76fe16a303fe969 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 246 2.0E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS07785 57985a1f5343d6cda76fe16a303fe969 253 Gene3D G3DSA:1.10.3720.10 11 252 5.6E-25 T 29-03-2018 HVS_RS07785 57985a1f5343d6cda76fe16a303fe969 253 SUPERFAMILY SSF161098 53 236 4.19E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS07205 09a91155c4a8febf00f3ee51bbe63d5d 284 SMART SM00646 146 264 4.6E-30 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HVS_RS07205 09a91155c4a8febf00f3ee51bbe63d5d 284 Gene3D G3DSA:3.40.630.40 83 270 1.1E-51 T 29-03-2018 HVS_RS07205 09a91155c4a8febf00f3ee51bbe63d5d 284 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 88 263 3.4E-44 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HVS_RS07205 09a91155c4a8febf00f3ee51bbe63d5d 284 SUPERFAMILY SSF53187 87 268 2.2E-49 T 29-03-2018 HVS_RS05020 144c98ef40a7e006ba4d8115413b307d 682 TIGRFAM TIGR03986 TIGR03986: CRISPR-associated protein 15 580 1.2E-121 T 29-03-2018 IPR023825 CRISPR-associated RAMP BGP1436 HVS_RS05020 144c98ef40a7e006ba4d8115413b307d 682 Pfam PF03787 RAMP superfamily 53 515 2.9E-9 T 29-03-2018 IPR005537 CRISPR type III-associated RAMP protein HVS_RS11635 7b72065e5b5e4926b668029f82763bc0 79 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 75 1.3E-20 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HVS_RS11635 7b72065e5b5e4926b668029f82763bc0 79 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 1.3E-10 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HVS_RS11635 7b72065e5b5e4926b668029f82763bc0 79 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.3E-10 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HVS_RS11635 7b72065e5b5e4926b668029f82763bc0 79 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.3E-10 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HVS_RS11635 7b72065e5b5e4926b668029f82763bc0 79 Pfam PF03840 Preprotein translocase SecG subunit 5 74 5.7E-20 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HVS_RS13775 e0b258ab61f23f77396bb3c180086e8c 963 Gene3D G3DSA:3.40.50.300 31 350 3.0E-7 T 29-03-2018 HVS_RS13775 e0b258ab61f23f77396bb3c180086e8c 963 SUPERFAMILY SSF52540 32 51 1.1E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13775 e0b258ab61f23f77396bb3c180086e8c 963 SUPERFAMILY SSF52540 136 252 1.1E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13775 e0b258ab61f23f77396bb3c180086e8c 963 SUPERFAMILY SSF52540 294 349 1.1E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13775 e0b258ab61f23f77396bb3c180086e8c 963 Pfam PF04851 Type III restriction enzyme, res subunit 121 345 1.5E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS04730 9fb1fbb556aac81602fb7aa7e5f54ab1 286 SMART SM00382 26 210 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04730 9fb1fbb556aac81602fb7aa7e5f54ab1 286 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS04730 9fb1fbb556aac81602fb7aa7e5f54ab1 286 SUPERFAMILY SSF52540 3 220 1.85E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04730 9fb1fbb556aac81602fb7aa7e5f54ab1 286 Pfam PF00005 ABC transporter 20 161 1.5E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS04730 9fb1fbb556aac81602fb7aa7e5f54ab1 286 Gene3D G3DSA:3.40.50.300 1 245 1.0E-59 T 29-03-2018 HVS_RS01475 82f18c864353369dadbb7de87d5a1da9 297 PRINTS PR00069 Aldo-keto reductase signature 92 110 1.0E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS01475 82f18c864353369dadbb7de87d5a1da9 297 PRINTS PR00069 Aldo-keto reductase signature 123 140 1.0E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS01475 82f18c864353369dadbb7de87d5a1da9 297 PRINTS PR00069 Aldo-keto reductase signature 35 59 1.0E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HVS_RS01475 82f18c864353369dadbb7de87d5a1da9 297 Pfam PF00248 Aldo/keto reductase family 2 266 2.5E-43 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS01475 82f18c864353369dadbb7de87d5a1da9 297 Gene3D G3DSA:3.20.20.100 1 280 3.8E-45 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS01475 82f18c864353369dadbb7de87d5a1da9 297 SUPERFAMILY SSF51430 3 266 1.7E-49 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain HVS_RS14035 8b9af6ae235e0792ee736b34f64fb584 165 Pfam PF14221 Domain of unknown function (DUF4330) 1 161 8.6E-31 T 29-03-2018 IPR025480 Protein of unknown function DUF4330 HVS_RS13640 692df7b6a9e2f9f629d6dfe20b82ff27 225 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 5 208 1.7E-57 T 29-03-2018 IPR013412 CRISPR-associated RAMP Csm3 HVS_RS13640 692df7b6a9e2f9f629d6dfe20b82ff27 225 Pfam PF03787 RAMP superfamily 13 207 1.3E-14 T 29-03-2018 IPR005537 CRISPR type III-associated RAMP protein HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 3 314 2.0E-112 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 SUPERFAMILY SSF51726 393 754 8.89E-107 T 29-03-2018 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 428 751 9.5E-141 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 6 755 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 Gene3D G3DSA:3.20.20.210 1 387 5.7E-122 T 29-03-2018 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 Gene3D G3DSA:3.20.20.210 388 757 6.5E-112 T 29-03-2018 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 SUPERFAMILY SSF51726 1 375 4.71E-92 T 29-03-2018 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 1 756 33.233 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HVS_RS13750 d3df68e6b7419f91cb5dda8f97199704 759 PIRSF PIRSF000382 1 759 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 HVS_RS04010 32d22c095b92c851dd08620974094a02 131 Gene3D G3DSA:2.170.16.10 2 103 5.8E-8 T 29-03-2018 HVS_RS04010 32d22c095b92c851dd08620974094a02 131 Pfam PF07591 Pretoxin HINT domain 7 38 6.3E-8 T 29-03-2018 HVS_RS04010 32d22c095b92c851dd08620974094a02 131 SUPERFAMILY SSF51294 4 38 5.23E-6 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04010 32d22c095b92c851dd08620974094a02 131 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 14 38 1.1E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS09260 7bff1e40709cd5bc50f2e3ee58ab3474 229 Gene3D G3DSA:3.40.50.150 2 162 1.7E-19 T 29-03-2018 HVS_RS09260 7bff1e40709cd5bc50f2e3ee58ab3474 229 Pfam PF12847 Methyltransferase domain 5 153 3.4E-56 T 29-03-2018 HVS_RS09260 7bff1e40709cd5bc50f2e3ee58ab3474 229 PIRSF PIRSF018637 1 229 2.7E-77 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 HVS_RS09260 7bff1e40709cd5bc50f2e3ee58ab3474 229 SUPERFAMILY SSF53335 11 140 1.8E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 178 207 3.0E-14 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 252 279 3.0E-14 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 281 310 3.0E-14 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 Pfam PF13407 Periplasmic binding protein domain 446 696 2.8E-38 T 29-03-2018 IPR025997 Periplasmic binding protein HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 SUPERFAMILY SSF58104 132 429 8.37E-46 T 29-03-2018 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 Gene3D G3DSA:3.40.50.2300 438 562 9.5E-15 T 29-03-2018 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 SMART SM00283 154 429 2.5E-30 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 Gene3D G3DSA:1.10.287.950 188 433 1.7E-40 T 29-03-2018 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 Gene3D G3DSA:1.10.287.950 94 187 7.2E-4 T 29-03-2018 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 Gene3D G3DSA:3.40.50.2300 563 695 1.1E-23 T 29-03-2018 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 211 376 9.4E-27 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS15280 30551448a8b29a5dbcc7b948c9ca91cd 723 SUPERFAMILY SSF53822 447 721 1.83E-44 T 29-03-2018 IPR028082 Periplasmic binding protein-like I HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 SUPERFAMILY SSF64288 61 242 4.55E-28 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 Pfam PF07702 UTRA domain 133 237 3.5E-18 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 SUPERFAMILY SSF46785 2 77 1.06E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.4E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.4E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 4.3E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 Gene3D G3DSA:1.10.10.10 1 72 1.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 SMART SM00345 14 73 3.3E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 SMART SM00866 94 238 9.2E-13 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HVS_RS09165 f9cd9cb813d92375ef5e55d4b1187629 248 Gene3D G3DSA:3.40.1410.10 73 246 1.7E-21 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 PIRSF PIRSF010376 2 291 8.3E-89 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 SUPERFAMILY SSF55060 167 283 8.15E-29 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 PRINTS PR00958 Homoserine kinase signature 107 122 7.9E-5 T 29-03-2018 HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 PRINTS PR00958 Homoserine kinase signature 245 260 7.9E-5 T 29-03-2018 HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 PRINTS PR00958 Homoserine kinase signature 8 23 7.9E-5 T 29-03-2018 HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 Pfam PF08544 GHMP kinases C terminal 203 278 1.1E-12 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 Gene3D G3DSA:3.30.70.890 166 291 1.8E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 289 34.099 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 SUPERFAMILY SSF54211 4 161 3.11E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 Gene3D G3DSA:3.30.230.10 4 163 1.0E-44 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 Pfam PF00288 GHMP kinases N terminal domain 90 148 2.0E-10 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 HVS_RS00175 e37588d3c17eda8b079e7d1151d87ac3 291 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4 275 5.7E-83 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 SUPERFAMILY SSF63446 398 469 3.92E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 ProSitePatterns PS00018 EF-hand calcium-binding domain. 403 415 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 Pfam PF00404 Dockerin type I repeat 439 459 1.1E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 Gene3D G3DSA:2.60.120.430 257 396 5.1E-5 T 29-03-2018 HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 SUPERFAMILY SSF49785 285 397 5.95E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 Gene3D G3DSA:1.10.1330.10 397 470 9.8E-5 T 29-03-2018 HVS_RS15660 56907eb781c651b2e3959bffe0419f09 477 Gene3D G3DSA:2.70.98.30 54 256 9.2E-13 T 29-03-2018 HVS_RS15625 a8dcac9e8d9c4dd26251854de6501174 516 Pfam PF01145 SPFH domain / Band 7 family 37 220 3.8E-21 T 29-03-2018 IPR001107 Band 7 domain HVS_RS15625 a8dcac9e8d9c4dd26251854de6501174 516 SMART SM00244 31 205 1.7E-5 T 29-03-2018 IPR001107 Band 7 domain HVS_RS15625 a8dcac9e8d9c4dd26251854de6501174 516 SUPERFAMILY SSF117892 70 209 8.24E-33 T 29-03-2018 IPR001107 Band 7 domain HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 Gene3D G3DSA:2.40.50.100 241 302 1.4E-15 T 29-03-2018 HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 SUPERFAMILY SSF50331 237 373 3.4E-28 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 Pfam PF03459 TOBE domain 311 364 4.5E-8 T 29-03-2018 IPR005116 Transport-associated OB, type 1 HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 Pfam PF00005 ABC transporter 21 162 6.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 Gene3D G3DSA:3.40.50.300 1 240 8.4E-72 T 29-03-2018 HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 SUPERFAMILY SSF52540 4 245 5.75E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 Gene3D G3DSA:2.40.50.140 303 358 7.9E-16 T 29-03-2018 HVS_RS14355 74fd0651df40ee2eb0500a5fcf0cd845 375 SMART SM00382 29 212 1.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 1.3E-144 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 SMART SM00382 122 256 3.5E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 Gene3D G3DSA:3.40.50.300 275 347 2.6E-11 T 29-03-2018 HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 Gene3D G3DSA:3.40.50.300 117 274 3.2E-25 T 29-03-2018 HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 SUPERFAMILY SSF52540 5 337 8.57E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 Pfam PF00437 Type II/IV secretion system protein 12 265 9.2E-42 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS11660 90ce835eea3552480fb1f51a6ce0a7d3 350 Gene3D G3DSA:3.30.450.90 1 100 7.6E-24 T 29-03-2018 HVS_RS08385 4a83a959f290cbaf5fdb508538c8650c 117 Hamap MF_00245 UPF0122 protein . 1 115 18.295 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like HVS_RS08385 4a83a959f290cbaf5fdb508538c8650c 117 SUPERFAMILY SSF88659 2 102 4.86E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS08385 4a83a959f290cbaf5fdb508538c8650c 117 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 92 1.0E-26 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like HVS_RS08385 4a83a959f290cbaf5fdb508538c8650c 117 Gene3D G3DSA:1.10.10.10 1 116 2.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS06445 59ad318fb0483fc327bbcd61eeafb619 99 SUPERFAMILY SSF54736 14 98 1.31E-29 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HVS_RS06445 59ad318fb0483fc327bbcd61eeafb619 99 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 11 94 25.544 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS HVS_RS06445 59ad318fb0483fc327bbcd61eeafb619 99 Gene3D G3DSA:3.30.1390.10 6 98 6.2E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HVS_RS06445 59ad318fb0483fc327bbcd61eeafb619 99 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 16 92 5.4E-34 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 508 521 - T 29-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 SMART SM00606 289 413 6.1E-34 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 SUPERFAMILY SSF49384 440 535 1.94E-28 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 SUPERFAMILY SSF49899 33 247 3.53E-55 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 SUPERFAMILY SSF49785 291 412 7.23E-29 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 Pfam PF00553 Cellulose binding domain 450 535 6.1E-25 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 ProSitePatterns PS01034 Glycosyl hydrolases family 16 active sites. 139 149 - T 29-03-2018 IPR008263 Glycoside hydrolase, family 16, active site GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 Gene3D G3DSA:2.60.40.290 441 538 1.1E-28 T 29-03-2018 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 Gene3D G3DSA:2.60.120.200 43 290 8.8E-46 T 29-03-2018 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 Gene3D G3DSA:2.60.120.260 291 416 2.1E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 Pfam PF03422 Carbohydrate binding module (family 6) 297 412 1.6E-25 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 136 151 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 152 165 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 210 232 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 234 246 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 96 114 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 115 131 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 170 187 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 PRINTS PR00737 Glycosyl hydrolase family 16 signature 190 207 4.8E-64 T 29-03-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 Pfam PF00722 Glycosyl hydrolases family 16 58 231 1.7E-43 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 HVS_RS12785 cf3344dbc1352102fb86f2902177f375 538 SMART SM00637 444 535 4.6E-30 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 HVS_RS15655 0f113e3e4c9ceecb0b812f8fc919a0eb 203 Gene3D G3DSA:3.40.50.360 1 203 4.4E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS15655 0f113e3e4c9ceecb0b812f8fc919a0eb 203 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 201 6.0E-100 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 HVS_RS15655 0f113e3e4c9ceecb0b812f8fc919a0eb 203 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 HVS_RS15655 0f113e3e4c9ceecb0b812f8fc919a0eb 203 Pfam PF03358 NADPH-dependent FMN reductase 1 145 9.6E-13 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HVS_RS15655 0f113e3e4c9ceecb0b812f8fc919a0eb 203 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 203 43.207 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 HVS_RS15655 0f113e3e4c9ceecb0b812f8fc919a0eb 203 SUPERFAMILY SSF52218 1 201 9.44E-65 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS05450 dfd09d6e3d8a792140304568b877b30d 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 31.415 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05450 dfd09d6e3d8a792140304568b877b30d 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 9.6E-60 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05450 dfd09d6e3d8a792140304568b877b30d 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 1.7E-56 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05450 dfd09d6e3d8a792140304568b877b30d 154 Gene3D G3DSA:3.40.50.960 70 154 1.0E-41 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05450 dfd09d6e3d8a792140304568b877b30d 154 Gene3D G3DSA:3.40.50.960 2 69 8.0E-23 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05450 dfd09d6e3d8a792140304568b877b30d 154 SUPERFAMILY SSF52121 6 154 1.83E-61 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05340 31eecfa1467f1a3f68421aeafb6c7d35 400 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 4 400 4.9E-142 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HVS_RS05340 31eecfa1467f1a3f68421aeafb6c7d35 400 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 400 145.875 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HVS_RS05340 31eecfa1467f1a3f68421aeafb6c7d35 400 SUPERFAMILY SSF56266 11 396 1.44E-135 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HVS_RS05340 31eecfa1467f1a3f68421aeafb6c7d35 400 Gene3D G3DSA:3.60.70.12 3 273 9.7E-104 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HVS_RS05340 31eecfa1467f1a3f68421aeafb6c7d35 400 Pfam PF01960 ArgJ family 15 400 8.7E-147 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 HVS_RS05340 31eecfa1467f1a3f68421aeafb6c7d35 400 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 22 398 1.0E-159 T 29-03-2018 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 4 107 32.666 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 SUPERFAMILY SSF141734 4 116 3.4E-50 T 29-03-2018 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 103 7.3E-36 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 128 214 22.374 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 Gene3D G3DSA:1.10.287.1080 127 218 3.8E-23 T 29-03-2018 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 131 217 5.9E-18 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 53 106 4.0E-22 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 6 218 36.525 T 29-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 131 214 3.1E-33 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 HVS_RS15240 cc36396a158f32d88273e5bd4f094877 218 SUPERFAMILY SSF101386 130 217 4.91E-27 T 29-03-2018 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 SUPERFAMILY SSF142019 110 351 1.19E-93 T 29-03-2018 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 Pfam PF10531 SLBB domain 354 403 7.3E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 159 330 9.6E-48 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 SUPERFAMILY SSF52833 5 95 2.68E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 5 81 3.7E-7 T 29-03-2018 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 SMART SM00928 440 485 7.8E-25 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 SUPERFAMILY SSF142984 352 435 1.57E-26 T 29-03-2018 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 441 523 1.6E-31 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 Gene3D G3DSA:3.40.30.10 3 103 5.2E-25 T 29-03-2018 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 SUPERFAMILY SSF140490 437 529 1.01E-35 T 29-03-2018 HVS_RS11450 a3c690c9514be3530812e140b9ac0df6 548 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 453 464 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS13970 919fc788bcc6bc2b328769f9b4b26d9e 150 Pfam PF00011 Hsp20/alpha crystallin family 49 150 3.0E-20 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain HVS_RS13970 919fc788bcc6bc2b328769f9b4b26d9e 150 Gene3D G3DSA:2.60.40.790 14 150 9.2E-34 T 29-03-2018 IPR008978 HSP20-like chaperone HVS_RS13970 919fc788bcc6bc2b328769f9b4b26d9e 150 SUPERFAMILY SSF49764 24 149 1.16E-34 T 29-03-2018 IPR008978 HSP20-like chaperone HVS_RS09090 fc00a5e0e25c11fc65402e5c339a2c4b 539 SUPERFAMILY SSF53067 14 260 1.08E-31 T 29-03-2018 HVS_RS09090 fc00a5e0e25c11fc65402e5c339a2c4b 539 Gene3D G3DSA:3.30.420.40 263 535 2.1E-33 T 29-03-2018 HVS_RS09090 fc00a5e0e25c11fc65402e5c339a2c4b 539 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 276 473 2.4E-30 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 HVS_RS09090 fc00a5e0e25c11fc65402e5c339a2c4b 539 SUPERFAMILY SSF53067 272 488 6.22E-16 T 29-03-2018 HVS_RS09090 fc00a5e0e25c11fc65402e5c339a2c4b 539 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 15 241 4.6E-18 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 HVS_RS09090 fc00a5e0e25c11fc65402e5c339a2c4b 539 Gene3D G3DSA:3.30.420.40 9 262 7.0E-40 T 29-03-2018 HVS_RS10275 484b262e5007389f382ef9f828bb3ac2 137 PIRSF PIRSF002889 7 135 1.9E-34 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HVS_RS10275 484b262e5007389f382ef9f828bb3ac2 137 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 12 133 7.0E-32 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 11 396 44.425 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 SUPERFAMILY SSF53748 4 396 2.83E-166 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PIRSF PIRSF000724 1 397 2.2E-162 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 194 213 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 113 128 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 171 193 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 372 389 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 35 57 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 PRINTS PR00477 Phosphoglycerate kinase family signature 141 163 1.5E-100 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 Pfam PF00162 Phosphoglycerate kinase 9 386 9.6E-174 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 Gene3D G3DSA:3.40.50.1260 6 182 3.1E-78 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11990 519197cb806ca211ec5ff8d9b86200fc 397 Gene3D G3DSA:3.40.50.1260 183 384 3.5E-93 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS13630 0487d60ea55bed224ef825383a2015ba 774 Gene3D G3DSA:3.30.70.270 544 671 0.0019 T 29-03-2018 HVS_RS13630 0487d60ea55bed224ef825383a2015ba 774 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 9 641 1.1E-102 T 29-03-2018 IPR013408 CRISPR-associated protein Csm1 HVS_RS02560 6e964101270af0a6bba7d3bf11d08c7f 314 Pfam PF00691 OmpA family 169 276 8.1E-14 T 29-03-2018 IPR006665 OmpA-like domain HVS_RS02560 6e964101270af0a6bba7d3bf11d08c7f 314 Gene3D G3DSA:3.30.1330.60 56 310 4.0E-29 T 29-03-2018 IPR006665 OmpA-like domain HVS_RS02560 6e964101270af0a6bba7d3bf11d08c7f 314 SUPERFAMILY SSF103088 156 282 1.02E-23 T 29-03-2018 IPR006665 OmpA-like domain HVS_RS14390 029ca40448b050015c3fba43b51cd756 585 SUPERFAMILY SSF55874 469 581 1.92E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS14390 029ca40448b050015c3fba43b51cd756 585 Gene3D G3DSA:3.30.565.10 453 585 1.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS14390 029ca40448b050015c3fba43b51cd756 585 Gene3D G3DSA:3.30.450.20 235 391 4.9E-11 T 29-03-2018 HVS_RS14390 029ca40448b050015c3fba43b51cd756 585 Pfam PF16927 N-terminal 7TM region of histidine kinase 15 233 1.3E-44 T 29-03-2018 IPR031621 Histidine kinase, N-terminal 7TM region HVS_RS14390 029ca40448b050015c3fba43b51cd756 585 Pfam PF07730 Histidine kinase 389 455 1.2E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HVS_RS15315 ce5d0ffb55479c7cd44bdc37c4ba6544 686 Pfam PF04055 Radical SAM superfamily 118 267 5.7E-24 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS15315 ce5d0ffb55479c7cd44bdc37c4ba6544 686 Pfam PF13353 4Fe-4S single cluster domain 118 204 1.7E-9 T 29-03-2018 HVS_RS15315 ce5d0ffb55479c7cd44bdc37c4ba6544 686 SMART SM00729 111 305 0.0011 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS15315 ce5d0ffb55479c7cd44bdc37c4ba6544 686 Gene3D G3DSA:3.20.20.70 112 381 1.3E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS15315 ce5d0ffb55479c7cd44bdc37c4ba6544 686 SUPERFAMILY SSF102114 115 368 2.22E-49 T 29-03-2018 HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 Pfam PF13487 HD domain 407 468 7.0E-21 T 29-03-2018 HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 Gene3D G3DSA:1.10.3210.10 322 520 1.1E-48 T 29-03-2018 HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 Gene3D G3DSA:3.30.70.270 148 321 2.2E-43 T 29-03-2018 HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 SUPERFAMILY SSF55073 160 320 1.41E-39 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 SMART SM00471 351 486 3.2E-13 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 SMART SM00267 144 319 3.2E-44 T 29-03-2018 IPR000160 GGDEF domain HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 SUPERFAMILY SSF109604 342 516 5.56E-39 T 29-03-2018 HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 151 318 6.3E-43 T 29-03-2018 IPR000160 GGDEF domain HVS_RS12040 45a548be2f45adfed4587914804e8e94 520 Pfam PF00990 Diguanylate cyclase, GGDEF domain 155 314 5.7E-38 T 29-03-2018 IPR000160 GGDEF domain HVS_RS12755 f521c88fa1c2457ca71a48d91fc02e2d 441 Pfam PF12698 ABC-2 family transporter protein 29 416 1.0E-22 T 29-03-2018 HVS_RS10755 87c010021294e024669095ea970b90fc 252 SUPERFAMILY SSF56214 5 97 7.85E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS10755 87c010021294e024669095ea970b90fc 252 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 104 205 8.8E-17 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS10755 87c010021294e024669095ea970b90fc 252 Gene3D G3DSA:3.90.470.20 113 206 8.4E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS10755 87c010021294e024669095ea970b90fc 252 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 102 214 1.2E-20 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HVS_RS10755 87c010021294e024669095ea970b90fc 252 Gene3D G3DSA:3.90.470.20 2 112 1.1E-22 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS10755 87c010021294e024669095ea970b90fc 252 SUPERFAMILY SSF56214 104 217 5.62E-27 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Gene3D G3DSA:1.10.150.20 184 247 2.0E-32 T 29-03-2018 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 269 1.3E-34 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Gene3D G3DSA:3.40.50.1010 4 183 5.7E-64 T 29-03-2018 IPR029060 PIN domain-like HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SUPERFAMILY SSF53098 306 485 4.7E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SMART SM00279 176 211 2.4E-19 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SMART SM00475 4 265 4.5E-122 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Pfam PF00476 DNA polymerase family A 515 891 3.6E-159 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SUPERFAMILY SSF56672 487 892 1.22E-156 T 29-03-2018 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Gene3D G3DSA:1.20.1060.10 451 617 1.8E-53 T 29-03-2018 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SUPERFAMILY SSF88723 3 173 1.8E-48 T 29-03-2018 IPR029060 PIN domain-like HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 173 1.6E-49 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 756 767 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 810 826 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 778 789 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 642 657 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 719 744 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 619 641 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 665 688 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 695 708 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 PRINTS PR00868 DNA-polymerase family A (pol I) signature 840 853 3.5E-77 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 ProSitePatterns PS00447 DNA polymerase family A signature. 719 738 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Gene3D G3DSA:3.30.420.10 284 450 1.9E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Pfam PF01612 3'-5' exonuclease 344 455 5.5E-9 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Gene3D G3DSA:3.30.70.370 618 709 5.9E-17 T 29-03-2018 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 Gene3D G3DSA:3.30.70.370 719 893 3.6E-52 T 29-03-2018 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SMART SM00482 650 857 1.0E-115 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 TIGRFAM TIGR00593 pola: DNA polymerase I 7 893 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS08770 5f27655823a15bc08ccd73cad7b1f52d 893 SUPERFAMILY SSF47807 174 288 1.79E-35 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 SUPERFAMILY SSF63446 546 610 6.77E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Gene3D G3DSA:2.60.40.1180 434 544 1.7E-21 T 29-03-2018 HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Gene3D G3DSA:3.20.20.80 46 433 1.8E-29 T 29-03-2018 HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Gene3D G3DSA:2.60.120.260 709 862 2.1E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Pfam PF12891 Glycoside hydrolase family 44 79 312 2.1E-72 T 29-03-2018 IPR024745 Glycoside hydrolase, family 44 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 SUPERFAMILY SSF51011 444 538 2.4E-6 T 29-03-2018 HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 SUPERFAMILY SSF49299 616 704 1.57E-19 T 29-03-2018 IPR000601 PKD domain HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Gene3D G3DSA:2.60.40.10 615 708 4.4E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 SMART SM00089 620 705 5.5E-21 T 29-03-2018 IPR022409 PKD/Chitinase domain HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 SUPERFAMILY SSF51445 337 428 1.6E-18 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 SUPERFAMILY SSF51445 59 310 1.6E-18 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Pfam PF00801 PKD domain 631 692 2.4E-14 T 29-03-2018 IPR000601 PKD domain HVS_RS00300 aa7c62da32b36fb2e42a0f17a64adac9 863 Pfam PF00404 Dockerin type I repeat 550 570 1.3E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS05410 72f14c9ff92f4002de8d492871bd3218 131 Gene3D G3DSA:3.40.50.1380 1 130 3.2E-29 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS05410 72f14c9ff92f4002de8d492871bd3218 131 Pfam PF02142 MGS-like domain 15 106 2.8E-11 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS05410 72f14c9ff92f4002de8d492871bd3218 131 PIRSF PIRSF006614 1 131 5.4E-47 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 HVS_RS05410 72f14c9ff92f4002de8d492871bd3218 131 SUPERFAMILY SSF52335 1 129 9.55E-45 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS05410 72f14c9ff92f4002de8d492871bd3218 131 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 120 5.1E-44 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 HVS_RS05410 72f14c9ff92f4002de8d492871bd3218 131 SMART SM00851 14 106 1.6E-13 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain HVS_RS01970 3def7ce5874f25c93aeac94610b79b5f 275 SMART SM00943 9 184 2.0E-58 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS01970 3def7ce5874f25c93aeac94610b79b5f 275 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 10 183 5.6E-44 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS01970 3def7ce5874f25c93aeac94610b79b5f 275 Pfam PF08708 Primase C terminal 1 (PriCT-1) 203 267 2.6E-18 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS01970 3def7ce5874f25c93aeac94610b79b5f 275 SMART SM00942 201 267 2.6E-23 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS01970 3def7ce5874f25c93aeac94610b79b5f 275 SUPERFAMILY SSF56747 39 193 4.45E-26 T 29-03-2018 HVS_RS08265 8ad31579c6489ff77ae3d9f5f73c3608 140 PIRSF PIRSF037663 1 138 3.3E-12 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted HVS_RS08265 8ad31579c6489ff77ae3d9f5f73c3608 140 Pfam PF00583 Acetyltransferase (GNAT) family 29 125 1.8E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS08265 8ad31579c6489ff77ae3d9f5f73c3608 140 SUPERFAMILY SSF55729 1 130 1.2E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS08265 8ad31579c6489ff77ae3d9f5f73c3608 140 Gene3D G3DSA:3.40.630.30 1 140 4.2E-29 T 29-03-2018 HVS_RS09750 f163e6024043f58ddf281ac21a5a3d74 293 SUPERFAMILY SSF111331 3 281 6.15E-80 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain HVS_RS09750 f163e6024043f58ddf281ac21a5a3d74 293 Hamap MF_00361 NAD kinase [nadK]. 2 283 31.257 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HVS_RS09750 f163e6024043f58ddf281ac21a5a3d74 293 Pfam PF01513 ATP-NAD kinase 57 267 2.6E-55 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HVS_RS09750 f163e6024043f58ddf281ac21a5a3d74 293 Gene3D G3DSA:2.60.200.30 137 260 3.4E-38 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 HVS_RS09750 f163e6024043f58ddf281ac21a5a3d74 293 Gene3D G3DSA:3.40.50.10330 1 136 3.4E-33 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 SUPERFAMILY SSF46785 1 88 1.24E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 Gene3D G3DSA:3.40.190.10 94 187 5.7E-7 T 29-03-2018 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 Gene3D G3DSA:3.40.190.10 188 273 2.8E-6 T 29-03-2018 HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 Pfam PF03466 LysR substrate binding domain 119 290 1.1E-10 T 29-03-2018 IPR005119 LysR, substrate-binding HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 Gene3D G3DSA:1.10.10.10 1 83 1.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13740 4aadc5935d0325734dd6639bd42b95dd 308 SUPERFAMILY SSF53850 88 296 6.52E-24 T 29-03-2018 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 3.3E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 124 140 3.3E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 87 102 3.3E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 TIGRFAM TIGR00077 lspA: signal peptidase II 2 147 3.0E-35 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 ProSitePatterns PS00855 Signal peptidases II signature. 90 102 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 149 16.372 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS09355 357c942b7286ffc5080307b99bc8ca20 159 Pfam PF01252 Signal peptidase (SPase) II 6 144 2.2E-36 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 HVS_RS11250 e0aa75e15e1c23864ffa6386bc4bad97 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HVS_RS11250 e0aa75e15e1c23864ffa6386bc4bad97 389 Gene3D G3DSA:3.90.1150.10 295 388 7.1E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS11250 e0aa75e15e1c23864ffa6386bc4bad97 389 SUPERFAMILY SSF53383 7 386 5.45E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS11250 e0aa75e15e1c23864ffa6386bc4bad97 389 Pfam PF00155 Aminotransferase class I and II 31 380 2.5E-74 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS11250 e0aa75e15e1c23864ffa6386bc4bad97 389 Gene3D G3DSA:3.40.640.10 46 294 1.0E-64 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS02115 04ef672aa69b2d06875bb7251918e681 274 SUPERFAMILY SSF56281 13 273 4.6E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02115 04ef672aa69b2d06875bb7251918e681 274 Pfam PF00753 Metallo-beta-lactamase superfamily 22 131 1.8E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02115 04ef672aa69b2d06875bb7251918e681 274 Gene3D G3DSA:3.60.15.10 1 262 1.1E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02115 04ef672aa69b2d06875bb7251918e681 274 SMART SM00849 20 186 8.7E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS08185 f14137e3ce2a8990ea5948f4862a7e40 132 SUPERFAMILY SSF47413 8 68 3.1E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS08185 f14137e3ce2a8990ea5948f4862a7e40 132 Gene3D G3DSA:1.10.260.40 8 130 2.6E-9 T 29-03-2018 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 Gene3D G3DSA:1.10.287.950 1 102 3.2E-4 T 29-03-2018 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 SUPERFAMILY SSF53822 367 587 1.11E-27 T 29-03-2018 IPR028082 Periplasmic binding protein-like I HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 Pfam PF13407 Periplasmic binding protein domain 367 588 2.3E-25 T 29-03-2018 IPR025997 Periplasmic binding protein HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 202 231 6.5E-11 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 173 200 6.5E-11 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 96 125 6.5E-11 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 150 301 4.1E-23 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 Gene3D G3DSA:3.40.50.2300 359 481 3.2E-12 T 29-03-2018 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 SUPERFAMILY SSF58104 53 349 5.36E-47 T 29-03-2018 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 SMART SM00283 75 350 1.4E-25 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 Gene3D G3DSA:3.40.50.2300 482 591 4.3E-7 T 29-03-2018 HVS_RS00375 f9e6d2305f78e52bf380db9f1a746d9b 597 Gene3D G3DSA:1.10.287.950 103 354 1.9E-40 T 29-03-2018 HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 Gene3D G3DSA:3.40.50.2300 1 115 5.3E-33 T 29-03-2018 HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 Pfam PF00072 Response regulator receiver domain 4 113 2.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 SMART SM00862 144 221 2.6E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 SUPERFAMILY SSF52172 1 177 6.83E-38 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 220 1.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 Gene3D G3DSA:1.10.10.10 116 223 6.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10810 9d6765c85051a6ccdd75747c2f4bebf5 223 SMART SM00448 2 112 6.5E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 Gene3D G3DSA:3.40.640.10 49 307 3.4E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 166 190 1.0E-10 T 29-03-2018 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 235 259 1.0E-10 T 29-03-2018 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 98 118 1.0E-10 T 29-03-2018 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 Pfam PF00155 Aminotransferase class I and II 34 380 1.7E-51 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 SUPERFAMILY SSF53383 29 390 5.03E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS07090 7a83f52de4ab91c266a9826f7624f2fd 395 Gene3D G3DSA:3.90.1150.10 308 393 1.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 SMART SM01005 247 376 2.4E-76 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 Pfam PF00842 Alanine racemase, C-terminal domain 247 375 7.2E-49 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 Pfam PF01168 Alanine racemase, N-terminal domain 12 233 1.5E-73 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 SUPERFAMILY SSF50621 241 383 1.22E-55 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 263 278 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 301 318 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 31 47 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 67 85 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 206 233 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 280 295 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 358 371 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 128 140 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 PRINTS PR00992 Alanine racemase signature 163 174 3.5E-66 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 SUPERFAMILY SSF51419 12 248 2.18E-70 T 29-03-2018 IPR029066 PLP-binding barrel HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 Hamap MF_01201 Alanine racemase. 5 376 36.825 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 Gene3D G3DSA:3.20.20.10 3 232 8.2E-55 T 29-03-2018 IPR029066 PLP-binding barrel HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 TIGRFAM TIGR00492 alr: alanine racemase 7 376 8.1E-131 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 HVS_RS14015 93a2fb53129a5d8c146a12bd4c887de1 389 Gene3D G3DSA:2.40.37.10 233 385 7.2E-67 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 PRINTS PR00598 Bacterial regulatory protein MarR family signature 288 303 1.4E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 PRINTS PR00598 Bacterial regulatory protein MarR family signature 337 357 1.4E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 PRINTS PR00598 Bacterial regulatory protein MarR family signature 271 287 1.4E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 PRINTS PR00598 Bacterial regulatory protein MarR family signature 307 323 1.4E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 Gene3D G3DSA:1.10.10.10 223 362 2.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 Pfam PF01047 MarR family 254 311 6.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 SMART SM00347 247 347 9.6E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS03665 2d4851c35262a3aa2de0d0aca8658cb9 383 SUPERFAMILY SSF46785 228 360 7.03E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11925 58a69d1aca917d8f546c34762a1d5f82 182 Gene3D G3DSA:3.20.130.10 1 174 6.8E-75 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HVS_RS11925 58a69d1aca917d8f546c34762a1d5f82 182 SUPERFAMILY SSF117457 3 174 1.18E-63 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HVS_RS11925 58a69d1aca917d8f546c34762a1d5f82 182 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 14 174 6.5E-56 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HVS_RS11925 58a69d1aca917d8f546c34762a1d5f82 182 Pfam PF05683 Fumarase C-terminus 9 174 4.9E-61 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 Pfam PF02195 ParB-like nuclease domain 22 110 1.9E-24 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 Gene3D G3DSA:3.90.1530.10 8 111 9.7E-36 T 29-03-2018 HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 SUPERFAMILY SSF110849 20 113 1.86E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 22 194 2.4E-53 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 SUPERFAMILY SSF109709 104 211 5.75E-34 T 29-03-2018 HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 Gene3D G3DSA:1.10.10.730 112 159 4.9E-20 T 29-03-2018 HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 SMART SM00470 21 111 1.9E-33 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS16165 fac5622c72388a42ff724d0f68cb803b 277 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 20 277 2.0E-105 T 29-03-2018 IPR023705 Nucleoid occlusion protein HVS_RS11955 7abc3afe3ed2560e00c317195038b585 305 SMART SM00448 3 117 6.5E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS11955 7abc3afe3ed2560e00c317195038b585 305 Pfam PF00072 Response regulator receiver domain 5 117 2.4E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS11955 7abc3afe3ed2560e00c317195038b585 305 Gene3D G3DSA:3.40.50.2300 2 136 1.5E-16 T 29-03-2018 HVS_RS11955 7abc3afe3ed2560e00c317195038b585 305 SUPERFAMILY SSF52172 4 127 1.15E-16 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS11770 16687749494ec7c41a3b80f539561e6e 258 SUPERFAMILY SSF88946 32 113 3.53E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11770 16687749494ec7c41a3b80f539561e6e 258 Pfam PF04542 Sigma-70 region 2 45 114 2.2E-4 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11770 16687749494ec7c41a3b80f539561e6e 258 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 25 249 25.3 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS11770 16687749494ec7c41a3b80f539561e6e 258 Gene3D G3DSA:1.10.1740.10 28 113 3.6E-9 T 29-03-2018 HVS_RS11770 16687749494ec7c41a3b80f539561e6e 258 PIRSF PIRSF038953 15 258 5.9E-69 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS11770 16687749494ec7c41a3b80f539561e6e 258 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 30 247 2.6E-58 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS05825 91ea390dcecef08659b3604c15ac3271 285 SUPERFAMILY SSF55383 56 139 3.14E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05825 91ea390dcecef08659b3604c15ac3271 285 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 1.9E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05825 91ea390dcecef08659b3604c15ac3271 285 Gene3D G3DSA:3.30.457.10 128 266 1.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05825 91ea390dcecef08659b3604c15ac3271 285 Gene3D G3DSA:3.30.457.10 6 64 1.9E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05825 91ea390dcecef08659b3604c15ac3271 285 Gene3D G3DSA:3.30.457.10 65 127 2.1E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 SUPERFAMILY SSF88659 122 183 1.66E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 Gene3D G3DSA:1.10.1740.10 2 118 6.3E-21 T 29-03-2018 HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 Pfam PF04542 Sigma-70 region 2 23 90 9.8E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 Gene3D G3DSA:1.10.10.10 119 192 3.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 Pfam PF08281 Sigma-70, region 4 130 181 1.6E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 184 2.9E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11285 be22a85a35b59e2da108f661e5ef2605 193 SUPERFAMILY SSF88946 4 94 2.51E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS01305 99617fbf22a7e764804ed58e1391a8b7 671 Pfam PF01368 DHH family 352 507 4.5E-23 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS01305 99617fbf22a7e764804ed58e1391a8b7 671 Gene3D G3DSA:3.90.1640.10 330 547 3.0E-46 T 29-03-2018 HVS_RS01305 99617fbf22a7e764804ed58e1391a8b7 671 SUPERFAMILY SSF64182 353 652 6.93E-65 T 29-03-2018 HVS_RS01305 99617fbf22a7e764804ed58e1391a8b7 671 Gene3D G3DSA:3.30.70.270 155 321 1.2E-4 T 29-03-2018 HVS_RS01305 99617fbf22a7e764804ed58e1391a8b7 671 Pfam PF02272 DHHA1 domain 544 657 1.7E-11 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HVS_RS01305 99617fbf22a7e764804ed58e1391a8b7 671 PIRSF PIRSF026583 1 667 1.4E-221 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 Gene3D G3DSA:3.30.450.20 189 316 6.1E-14 T 29-03-2018 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 SMART SM00304 337 389 4.1E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 SMART SM00283 418 693 3.2E-59 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 Pfam PF02743 Cache domain 67 299 2.2E-15 T 29-03-2018 IPR033479 Double Cache domain 1 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 Gene3D G3DSA:1.10.287.950 349 453 2.5E-5 T 29-03-2018 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 Gene3D G3DSA:1.10.287.950 454 695 2.3E-44 T 29-03-2018 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 480 646 5.3E-38 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 SUPERFAMILY SSF58104 424 692 1.14E-63 T 29-03-2018 HVS_RS16160 fdb1f7afca843d76461215f89545a7a5 695 SUPERFAMILY SSF58104 358 391 1.14E-63 T 29-03-2018 HVS_RS12965 3ff00a48d68d87be937cec999519f728 179 SUPERFAMILY SSF160369 6 174 8.37E-56 T 29-03-2018 HVS_RS12965 3ff00a48d68d87be937cec999519f728 179 ProSitePatterns PS01109 Ribosomal protein L10 signature. 10 44 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12965 3ff00a48d68d87be937cec999519f728 179 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 5 174 26.056 T 29-03-2018 IPR022973 Ribosomal protein L10 HVS_RS12965 3ff00a48d68d87be937cec999519f728 179 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 169 4.0E-6 T 29-03-2018 HVS_RS12965 3ff00a48d68d87be937cec999519f728 179 Pfam PF00466 Ribosomal protein L10 8 103 3.1E-28 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 HVS_RS11985 36ec781bfd8f62e9e07aceedc9ee9e19 251 Pfam PF00121 Triosephosphate isomerase 5 247 1.1E-96 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11985 36ec781bfd8f62e9e07aceedc9ee9e19 251 SUPERFAMILY SSF51351 2 249 1.18E-97 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11985 36ec781bfd8f62e9e07aceedc9ee9e19 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11985 36ec781bfd8f62e9e07aceedc9ee9e19 251 Gene3D G3DSA:3.20.20.70 1 251 1.9E-104 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS11985 36ec781bfd8f62e9e07aceedc9ee9e19 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 239 9.6E-64 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11985 36ec781bfd8f62e9e07aceedc9ee9e19 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 250 41.235 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 PIRSF PIRSF006816 1 261 5.6E-71 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 SUPERFAMILY SSF63380 6 100 3.23E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 Gene3D G3DSA:3.40.50.80 100 216 1.1E-12 T 29-03-2018 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 SUPERFAMILY SSF52343 95 258 7.99E-32 T 29-03-2018 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 Pfam PF00175 Oxidoreductase NAD-binding domain 112 202 1.7E-5 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 Gene3D G3DSA:2.10.240.10 217 258 7.2E-20 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 Gene3D G3DSA:2.40.30.10 2 98 6.4E-13 T 29-03-2018 HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 217 257 1.3E-19 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain HVS_RS08895 1e6acb29ac2795d08e7c8a68a139b26b 261 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 259 35.356 T 29-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit HVS_RS10865 e84e849834f1eaa53b7c80dbdab6e0d2 145 Gene3D G3DSA:1.20.5.620 45 119 2.1E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS12580 adbdcf713a313494fcadd241c4dc1bfc 139 Pfam PF01814 Hemerythrin HHE cation binding domain 11 127 2.2E-6 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 HVS_RS12580 adbdcf713a313494fcadd241c4dc1bfc 139 Gene3D G3DSA:1.20.120.50 1 137 1.6E-30 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HVS_RS12580 adbdcf713a313494fcadd241c4dc1bfc 139 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 3 131 8.1E-29 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HVS_RS12580 adbdcf713a313494fcadd241c4dc1bfc 139 SUPERFAMILY SSF47188 2 131 2.09E-26 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 9.6E-7 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 9.6E-7 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 9.6E-7 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 Gene3D G3DSA:3.50.50.60 2 188 2.7E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.3E-7 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 2.3E-7 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 Gene3D G3DSA:2.40.30.10 192 287 2.6E-30 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 407 5.6E-148 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 SUPERFAMILY SSF160996 193 355 9.02E-51 T 29-03-2018 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 SUPERFAMILY SSF51905 1 194 6.86E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 SUPERFAMILY SSF51905 352 408 6.86E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS08105 6d214ba28a91a88dc9b0cc61129c9437 410 Pfam PF03486 HI0933-like protein 4 407 5.1E-145 T 29-03-2018 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 SUPERFAMILY SSF49384 39 188 1.23E-50 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 Gene3D G3DSA:2.60.40.680 39 193 1.2E-43 T 29-03-2018 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 Gene3D G3DSA:2.60.40.680 341 503 1.5E-27 T 29-03-2018 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 Gene3D G3DSA:2.60.40.680 1 32 7.3E-4 T 29-03-2018 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 SUPERFAMILY SSF49384 339 497 8.37E-39 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 Pfam PF00963 Cohesin domain 352 498 3.3E-15 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02505 48cc456b388496d9d6b4d41d3f915a10 943 Pfam PF00963 Cohesin domain 41 191 2.4E-28 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS07710 127ef7f08778314dfd3a02d0c8c8183c 269 Pfam PF09359 VTC domain 7 231 6.2E-38 T 29-03-2018 IPR018966 VTC domain HVS_RS07710 127ef7f08778314dfd3a02d0c8c8183c 269 Gene3D G3DSA:2.40.320.10 2 223 2.8E-32 T 29-03-2018 HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 PIRSF PIRSF037489 1 368 6.2E-147 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 Gene3D G3DSA:3.40.1390.30 224 353 9.1E-5 T 29-03-2018 HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 Gene3D G3DSA:3.30.70.120 132 223 1.1E-40 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 SUPERFAMILY SSF102705 3 365 2.22E-126 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 352 6.7E-86 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 Gene3D G3DSA:3.40.1390.30 1 124 3.5E-43 T 29-03-2018 HVS_RS09255 13780a3cff2f3ef416c77bab21b1573f 368 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 361 5.7E-76 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HVS_RS08030 fef8378af9418f3002d2601a44abfdcd 266 Pfam PF02811 PHP domain 3 194 2.5E-14 T 29-03-2018 IPR004013 PHP domain GO:0003824 HVS_RS08030 fef8378af9418f3002d2601a44abfdcd 266 Gene3D G3DSA:3.20.20.140 1 262 1.2E-44 T 29-03-2018 HVS_RS08030 fef8378af9418f3002d2601a44abfdcd 266 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 238 1.1E-48 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 HVS_RS08030 fef8378af9418f3002d2601a44abfdcd 266 SMART SM00481 2 84 1.7E-8 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HVS_RS08030 fef8378af9418f3002d2601a44abfdcd 266 SUPERFAMILY SSF89550 1 263 1.7E-47 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 Gene3D G3DSA:3.40.50.720 182 428 6.5E-67 T 29-03-2018 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 PIRSF PIRSF000185 4 428 6.4E-146 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 SMART SM00839 184 426 2.1E-75 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 426 2.9E-66 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 Gene3D G3DSA:3.40.50.10860 38 181 1.5E-54 T 29-03-2018 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 3.2E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 93 107 3.2E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 3.2E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 3.2E-33 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 101 114 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 36 163 6.7E-57 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 SUPERFAMILY SSF51735 182 427 6.81E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS10775 9e3c8c6159fe3ae95a9f49c4e0262c87 428 SUPERFAMILY SSF53223 6 184 5.12E-69 T 29-03-2018 HVS_RS14835 b701d603e1e545471bc044d4d65d332d 128 Gene3D G3DSA:1.10.150.80 18 105 1.4E-4 T 29-03-2018 HVS_RS05990 b701d603e1e545471bc044d4d65d332d 128 Gene3D G3DSA:1.10.150.80 18 105 1.4E-4 T 29-03-2018 HVS_RS03210 1695459ae1a021eb2a37a36285345412 181 Pfam PF03641 Possible lysine decarboxylase 47 177 7.3E-38 T 29-03-2018 IPR031100 LOG family HVS_RS03210 1695459ae1a021eb2a37a36285345412 181 SUPERFAMILY SSF102405 3 180 7.63E-56 T 29-03-2018 HVS_RS03210 1695459ae1a021eb2a37a36285345412 181 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 180 1.3E-53 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HVS_RS03210 1695459ae1a021eb2a37a36285345412 181 Gene3D G3DSA:3.40.50.450 1 181 2.4E-49 T 29-03-2018 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 Gene3D G3DSA:3.20.20.70 4 277 4.1E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 Pfam PF08666 SAF domain 292 348 2.0E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 18 343 5.8E-150 T 29-03-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 Gene3D G3DSA:3.90.1210.10 278 349 9.8E-29 T 29-03-2018 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 Pfam PF03102 NeuB family 38 276 6.0E-94 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 SMART SM00858 291 349 6.6E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 SUPERFAMILY SSF51569 5 303 2.2E-96 T 29-03-2018 HVS_RS01440 a35026db5f8706ea2ea5f85aa1bbbc63 349 SUPERFAMILY SSF51269 287 349 6.28E-22 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 213 4.1E-38 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 248 4.0E-79 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 SUPERFAMILY SSF53681 5 107 8.34E-36 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 Gene3D G3DSA:3.40.50.1860 114 268 2.7E-45 T 29-03-2018 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 Gene3D G3DSA:3.40.50.1860 2 113 1.6E-25 T 29-03-2018 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 SUPERFAMILY SSF53681 109 260 1.37E-40 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS01735 2483bf2cfbc80b582f6a7c7234e80b35 268 Hamap MF_00258 Glutamate racemase [murI]. 4 256 37.359 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS13505 87d171ac237017642c752e21b4cf389d 522 SUPERFAMILY SSF53041 21 171 3.66E-36 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS13505 87d171ac237017642c752e21b4cf389d 522 Pfam PF13408 Recombinase zinc beta ribbon domain 314 373 1.9E-13 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain HVS_RS13505 87d171ac237017642c752e21b4cf389d 522 SMART SM00857 22 171 7.8E-51 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS13505 87d171ac237017642c752e21b4cf389d 522 Pfam PF00239 Resolvase, N terminal domain 22 170 3.5E-34 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS13505 87d171ac237017642c752e21b4cf389d 522 Pfam PF07508 Recombinase 191 296 1.3E-27 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 HVS_RS13505 87d171ac237017642c752e21b4cf389d 522 Gene3D G3DSA:3.40.50.1390 16 180 1.0E-43 T 29-03-2018 HVS_RS00540 274c339935032321303384bb59799baa 1170 Pfam PF03461 TRCF domain 1028 1120 8.7E-30 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HVS_RS00540 274c339935032321303384bb59799baa 1170 Gene3D G3DSA:2.170.150.10 154 318 0.0028 T 29-03-2018 HVS_RS00540 274c339935032321303384bb59799baa 1170 Pfam PF02559 CarD-like/TRCF domain 503 598 5.5E-30 T 29-03-2018 IPR003711 CarD-like/TRCF domain HVS_RS00540 274c339935032321303384bb59799baa 1170 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 162 1100 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HVS_RS00540 274c339935032321303384bb59799baa 1170 SUPERFAMILY SSF141259 496 571 1.57E-22 T 29-03-2018 IPR003711 CarD-like/TRCF domain HVS_RS00540 274c339935032321303384bb59799baa 1170 SUPERFAMILY SSF52540 547 806 2.14E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00540 274c339935032321303384bb59799baa 1170 Pfam PF00271 Helicase conserved C-terminal domain 827 932 8.9E-17 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS00540 274c339935032321303384bb59799baa 1170 SMART SM00982 1027 1127 5.2E-41 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HVS_RS00540 274c339935032321303384bb59799baa 1170 SMART SM00487 623 813 6.5E-35 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS00540 274c339935032321303384bb59799baa 1170 SUPERFAMILY SSF52540 21 377 6.64E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00540 274c339935032321303384bb59799baa 1170 SUPERFAMILY SSF52540 389 487 7.86E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00540 274c339935032321303384bb59799baa 1170 Gene3D G3DSA:3.40.50.300 812 979 1.4E-25 T 29-03-2018 HVS_RS00540 274c339935032321303384bb59799baa 1170 SMART SM01058 502 599 7.5E-44 T 29-03-2018 IPR003711 CarD-like/TRCF domain HVS_RS00540 274c339935032321303384bb59799baa 1170 SUPERFAMILY SSF52540 805 1013 1.7E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00540 274c339935032321303384bb59799baa 1170 Gene3D G3DSA:3.40.50.300 45 149 0.13 T 29-03-2018 HVS_RS00540 274c339935032321303384bb59799baa 1170 Pfam PF00270 DEAD/DEAH box helicase 628 787 2.1E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS00540 274c339935032321303384bb59799baa 1170 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 52 1162 29.14 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HVS_RS00540 274c339935032321303384bb59799baa 1170 Gene3D G3DSA:3.40.50.300 608 810 1.0E-33 T 29-03-2018 HVS_RS00540 274c339935032321303384bb59799baa 1170 SUPERFAMILY SSF143517 1017 1166 1.14E-37 T 29-03-2018 HVS_RS00540 274c339935032321303384bb59799baa 1170 SMART SM00490 849 933 3.1E-17 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS00540 274c339935032321303384bb59799baa 1170 Gene3D G3DSA:3.40.50.300 378 593 0.05 T 29-03-2018 HVS_RS08750 ed2d0b44a0f60b8771af7bf2dfcea2a6 301 SUPERFAMILY SSF103481 186 289 1.7E-14 T 29-03-2018 HVS_RS08750 ed2d0b44a0f60b8771af7bf2dfcea2a6 301 SUPERFAMILY SSF103481 40 142 3.92E-14 T 29-03-2018 HVS_RS08750 ed2d0b44a0f60b8771af7bf2dfcea2a6 301 Pfam PF00892 EamA-like transporter family 6 140 1.3E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HVS_RS08750 ed2d0b44a0f60b8771af7bf2dfcea2a6 301 Pfam PF00892 EamA-like transporter family 155 286 2.1E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 HVS_RS09920 69d2b770311ddd1721b2f28ec76f413c 434 PIRSF PIRSF006444 1 433 1.0E-210 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 HVS_RS09920 69d2b770311ddd1721b2f28ec76f413c 434 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 431 2.0E-34 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal HVS_RS09920 69d2b770311ddd1721b2f28ec76f413c 434 Pfam PF00501 AMP-binding enzyme 84 285 1.8E-11 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS09920 69d2b770311ddd1721b2f28ec76f413c 434 Gene3D G3DSA:3.40.50.980 83 255 4.8E-16 T 29-03-2018 HVS_RS09920 69d2b770311ddd1721b2f28ec76f413c 434 Gene3D G3DSA:3.30.300.30 325 433 1.2E-10 T 29-03-2018 HVS_RS09920 69d2b770311ddd1721b2f28ec76f413c 434 SUPERFAMILY SSF56801 22 396 3.01E-54 T 29-03-2018 HVS_RS02440 0a9d47b38b46b5092f72d5c5b2121225 792 Pfam PF01841 Transglutaminase-like superfamily 509 626 1.5E-25 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS02440 0a9d47b38b46b5092f72d5c5b2121225 792 SMART SM00460 557 628 3.3E-18 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS02440 0a9d47b38b46b5092f72d5c5b2121225 792 SUPERFAMILY SSF54001 493 637 4.63E-35 T 29-03-2018 HVS_RS02440 0a9d47b38b46b5092f72d5c5b2121225 792 Gene3D G3DSA:3.90.260.10 502 649 2.3E-19 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Gene3D G3DSA:3.40.50.1700 338 589 3.5E-83 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Gene3D G3DSA:2.60.40.10 590 707 3.8E-31 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 SUPERFAMILY SSF52279 353 592 4.32E-58 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 SMART SM01217 626 694 2.2E-20 T 29-03-2018 IPR026891 Fibronectin type III-like domain HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Gene3D G3DSA:3.20.20.300 39 335 6.3E-104 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 353 589 4.7E-64 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Gene3D G3DSA:3.20.20.300 4 38 1.1E-5 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 45 310 3.9E-51 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 SUPERFAMILY SSF51445 6 352 2.32E-102 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 235 253 8.0E-12 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 69 88 8.0E-12 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 164 180 8.0E-12 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02315 4ce5c77ca0c2aaddafdec4362f1f96fc 723 Pfam PF14310 Fibronectin type III-like domain 626 693 7.9E-18 T 29-03-2018 IPR026891 Fibronectin type III-like domain HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 339 1.7E-126 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 4 343 70.948 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 PIRSF PIRSF006004 2 343 6.8E-130 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 Pfam PF04055 Radical SAM superfamily 108 267 1.3E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 SUPERFAMILY SSF102114 104 314 1.05E-15 T 29-03-2018 HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 Pfam PF13394 4Fe-4S single cluster domain 111 197 1.6E-6 T 29-03-2018 HVS_RS07055 538faf4f256f6fcd8502fdae291c0e05 343 Gene3D G3DSA:3.20.20.70 15 341 7.5E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS01235 70bb79759e551c964677850b9209d964 631 SMART SM00959 5 47 1.3E-9 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HVS_RS01235 70bb79759e551c964677850b9209d964 631 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 625 7.6E-185 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HVS_RS01235 70bb79759e551c964677850b9209d964 631 SMART SM00357 265 329 6.9E-16 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 HVS_RS01235 70bb79759e551c964677850b9209d964 631 Hamap MF_01884 Transcription termination factor Rho [rho]. 263 627 202.896 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 HVS_RS01235 70bb79759e551c964677850b9209d964 631 SUPERFAMILY SSF52540 328 579 1.46E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01235 70bb79759e551c964677850b9209d964 631 SMART SM00382 378 563 8.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01235 70bb79759e551c964677850b9209d964 631 SUPERFAMILY SSF68912 5 42 1.02E-5 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HVS_RS01235 70bb79759e551c964677850b9209d964 631 SUPERFAMILY SSF50249 265 336 1.8E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS01235 70bb79759e551c964677850b9209d964 631 Gene3D G3DSA:1.10.720.10 5 42 1.7E-10 T 29-03-2018 HVS_RS01235 70bb79759e551c964677850b9209d964 631 Pfam PF07497 Rho termination factor, RNA-binding domain 264 336 7.8E-33 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 HVS_RS01235 70bb79759e551c964677850b9209d964 631 Gene3D G3DSA:3.40.50.300 340 627 3.2E-47 T 29-03-2018 HVS_RS01235 70bb79759e551c964677850b9209d964 631 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 367 571 7.7E-20 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01235 70bb79759e551c964677850b9209d964 631 Gene3D G3DSA:2.40.50.140 263 327 1.4E-30 T 29-03-2018 HVS_RS01235 70bb79759e551c964677850b9209d964 631 Pfam PF07498 Rho termination factor, N-terminal domain 6 42 2.4E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 HVS_RS06120 b71575b855463f73530ce797047c4861 262 SUPERFAMILY SSF89550 1 202 9.61E-17 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS06120 b71575b855463f73530ce797047c4861 262 Gene3D G3DSA:3.20.20.140 1 247 2.5E-18 T 29-03-2018 HVS_RS06120 b71575b855463f73530ce797047c4861 262 PIRSF PIRSF016557 1 254 1.8E-71 T 29-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Pfam PF00457 Glycosyl hydrolases family 11 37 218 1.0E-66 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Gene3D G3DSA:1.10.1330.10 396 464 2.2E-4 T 29-03-2018 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 433 452 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 PRINTS PR00911 Glycosyl hydrolase family 11 signature 190 198 7.2E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 PRINTS PR00911 Glycosyl hydrolase family 11 signature 162 167 7.2E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 PRINTS PR00911 Glycosyl hydrolase family 11 signature 167 176 7.2E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 PRINTS PR00911 Glycosyl hydrolase family 11 signature 105 114 7.2E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 PRINTS PR00911 Glycosyl hydrolase family 11 signature 115 125 7.2E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 PRINTS PR00911 Glycosyl hydrolase family 11 signature 142 148 7.2E-16 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 SUPERFAMILY SSF88713 470 668 4.94E-50 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 115 125 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Gene3D G3DSA:3.20.20.370 479 680 1.1E-49 T 29-03-2018 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Pfam PF03422 Carbohydrate binding module (family 6) 263 382 7.3E-32 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 SUPERFAMILY SSF49785 256 382 3.74E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Pfam PF00404 Dockerin type I repeat 400 420 4.2E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 SUPERFAMILY SSF49899 27 227 2.04E-83 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Pfam PF01522 Polysaccharide deacetylase 480 593 5.9E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Gene3D G3DSA:2.60.120.260 253 385 8.7E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 SMART SM00606 255 382 4.4E-47 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 Gene3D G3DSA:2.60.120.180 21 226 2.2E-87 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS12830 82b81ea4e4000b10ab848c15b51dc34e 685 SUPERFAMILY SSF63446 396 463 5.23E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 Pfam PF00404 Dockerin type I repeat 31 51 7.8E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 SUPERFAMILY SSF63446 28 95 8.93E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 SUPERFAMILY SSF49590 245 325 3.27E-9 T 29-03-2018 IPR007117 Expansin, cellulose-binding-like domain HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 SUPERFAMILY SSF50685 137 242 1.29E-16 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 Gene3D G3DSA:2.40.40.10 129 253 1.6E-17 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 31 50 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 Gene3D G3DSA:2.60.40.760 254 324 2.3E-15 T 29-03-2018 IPR007117 Expansin, cellulose-binding-like domain HVS_RS03310 0ed12d979fe90fed3c4adf83aa238fdc 343 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 67 86 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00260 fe1ba8f643c589cc363dcb206f88bb27 283 Gene3D G3DSA:1.10.3720.10 14 276 8.1E-39 T 29-03-2018 HVS_RS00260 fe1ba8f643c589cc363dcb206f88bb27 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 274 2.5E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS00260 fe1ba8f643c589cc363dcb206f88bb27 283 SUPERFAMILY SSF161098 12 283 3.14E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 Gene3D G3DSA:3.40.50.150 76 448 1.2E-64 T 29-03-2018 HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 264 449 2.9E-25 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 SUPERFAMILY SSF53335 68 449 5.29E-90 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 18 442 1.8E-155 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 Gene3D G3DSA:2.40.50.140 2 75 2.6E-21 T 29-03-2018 HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 SUPERFAMILY SSF50249 3 60 1.03E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 Pfam PF01938 TRAM domain 8 59 1.2E-7 T 29-03-2018 IPR002792 TRAM domain HVS_RS13800 46153c5e6cc28ee328e05df76dee0ac3 450 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 380 411 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 SUPERFAMILY SSF50249 1 64 5.14E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.7E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 SMART SM00357 3 66 4.1E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 PIRSF PIRSF002599 1 66 5.5E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 PRINTS PR00050 Cold shock protein signature 24 33 2.1E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 PRINTS PR00050 Cold shock protein signature 39 57 2.1E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 PRINTS PR00050 Cold shock protein signature 4 19 2.1E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 HVS_RS14310 f708997338df734e0f9df88c134dcb18 66 Gene3D G3DSA:2.40.50.140 1 66 6.6E-28 T 29-03-2018 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 PIRSF PIRSF001267 1 498 1.5E-87 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 Pfam PF01966 HD domain 335 448 7.6E-6 T 29-03-2018 IPR006674 HD domain HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 SUPERFAMILY SSF53067 131 305 9.91E-44 T 29-03-2018 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 Pfam PF02541 Ppx/GppA phosphatase family 25 304 9.9E-54 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 Gene3D G3DSA:3.30.420.150 130 310 5.1E-41 T 29-03-2018 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 SUPERFAMILY SSF109604 318 505 1.34E-41 T 29-03-2018 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 Gene3D G3DSA:3.30.420.40 1 128 4.0E-31 T 29-03-2018 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 Gene3D G3DSA:1.10.3210.10 320 504 3.6E-7 T 29-03-2018 HVS_RS14700 14b978c698dc841a8b5dceb8450c065f 506 SUPERFAMILY SSF53067 5 129 6.61E-28 T 29-03-2018 HVS_RS08795 216a09a9033e354d315efc3f5db5043d 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 9.0E-22 T 29-03-2018 IPR007347 Sporulation stage V, protein S HVS_RS08795 216a09a9033e354d315efc3f5db5043d 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 9.8E-37 T 29-03-2018 IPR007347 Sporulation stage V, protein S HVS_RS07675 622c614baf769071e044570b75e0e05e 197 Pfam PF02915 Rubrerythrin 11 144 2.6E-28 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HVS_RS07675 622c614baf769071e044570b75e0e05e 197 SUPERFAMILY SSF57802 154 196 3.81E-12 T 29-03-2018 HVS_RS07675 622c614baf769071e044570b75e0e05e 197 Gene3D G3DSA:2.20.28.10 159 192 2.2E-7 T 29-03-2018 HVS_RS07675 622c614baf769071e044570b75e0e05e 197 SUPERFAMILY SSF47240 4 153 1.92E-39 T 29-03-2018 IPR009078 Ferritin-like superfamily HVS_RS07675 622c614baf769071e044570b75e0e05e 197 Gene3D G3DSA:1.20.1260.10 89 158 3.0E-15 T 29-03-2018 IPR012347 Ferritin-related HVS_RS07675 622c614baf769071e044570b75e0e05e 197 Gene3D G3DSA:1.20.1260.10 1 88 2.4E-17 T 29-03-2018 IPR012347 Ferritin-related HVS_RS03435 ae3616f5dc72a8ef87a1b9c2c1b01296 99 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 5.3E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03435 ae3616f5dc72a8ef87a1b9c2c1b01296 99 Gene3D G3DSA:1.10.287.850 1 93 5.7E-18 T 29-03-2018 HVS_RS03435 ae3616f5dc72a8ef87a1b9c2c1b01296 99 SUPERFAMILY SSF140453 3 94 6.8E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03435 ae3616f5dc72a8ef87a1b9c2c1b01296 99 Pfam PF06013 Proteins of 100 residues with WXG 4 87 1.5E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 5.6E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 5.6E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 5.6E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 5.6E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 465 40.158 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 SUPERFAMILY SSF47323 314 462 1.18E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 Gene3D G3DSA:3.40.50.620 1 303 5.8E-101 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 14 311 1.0E-136 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 Gene3D G3DSA:1.20.120.640 305 406 3.7E-23 T 29-03-2018 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 SMART SM00840 353 416 2.0E-21 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 Pfam PF09190 DALR domain 353 414 1.6E-17 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 462 7.7E-187 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 HVS_RS15715 d5bb9b9552b786020492ec3db12eb0aa 467 SUPERFAMILY SSF52374 2 310 2.95E-105 T 29-03-2018 HVS_RS10975 057c2cbbc593a261da470fc12e9b7653 352 Pfam PF02277 Phosphoribosyltransferase 11 345 1.0E-131 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS10975 057c2cbbc593a261da470fc12e9b7653 352 SUPERFAMILY SSF52733 6 347 7.32E-115 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS10975 057c2cbbc593a261da470fc12e9b7653 352 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 12 347 35.449 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS10975 057c2cbbc593a261da470fc12e9b7653 352 Gene3D G3DSA:3.40.50.10210 71 328 3.8E-105 T 29-03-2018 HVS_RS10975 057c2cbbc593a261da470fc12e9b7653 352 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 14 345 1.0E-133 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS10975 057c2cbbc593a261da470fc12e9b7653 352 Gene3D G3DSA:1.10.1610.10 4 70 3.6E-27 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS07640 920996f31e97cf4383c78398b998fa36 248 Gene3D G3DSA:3.40.50.970 6 76 8.2E-11 T 29-03-2018 HVS_RS07640 920996f31e97cf4383c78398b998fa36 248 Gene3D G3DSA:3.40.50.970 77 247 1.2E-35 T 29-03-2018 HVS_RS07640 920996f31e97cf4383c78398b998fa36 248 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 55 209 7.8E-24 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS07640 920996f31e97cf4383c78398b998fa36 248 SUPERFAMILY SSF52518 14 232 1.22E-57 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS13995 a853e75257b7b543be625f36cfe9294e 185 Gene3D G3DSA:3.90.20.10 10 102 9.7E-4 T 29-03-2018 HVS_RS08840 02f34d1d3bb1f7acdf2c7c6c4b6823ba 194 SUPERFAMILY SSF54637 76 182 2.06E-16 T 29-03-2018 IPR029069 HotDog domain HVS_RS08840 02f34d1d3bb1f7acdf2c7c6c4b6823ba 194 PIRSF PIRSF037733 1 191 4.6E-79 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 HVS_RS08840 02f34d1d3bb1f7acdf2c7c6c4b6823ba 194 Gene3D G3DSA:3.10.129.10 59 188 1.1E-13 T 29-03-2018 HVS_RS08840 02f34d1d3bb1f7acdf2c7c6c4b6823ba 194 SUPERFAMILY SSF46785 8 55 1.81E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08840 02f34d1d3bb1f7acdf2c7c6c4b6823ba 194 Gene3D G3DSA:1.10.10.10 2 58 1.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 Pfam PF07650 KH domain 38 111 4.1E-19 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 4.4E-40 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.3E-96 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 SMART SM00322 60 125 1.7E-10 T 29-03-2018 IPR004087 K Homology domain GO:0003676 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 SUPERFAMILY SSF54821 107 206 5.49E-40 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.371 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 SUPERFAMILY SSF54814 2 106 7.85E-40 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 Gene3D G3DSA:3.30.1140.32 108 208 7.1E-39 T 29-03-2018 HVS_RS15110 07ec791fd6e0f379bea698dbda3b251d 226 Gene3D G3DSA:3.30.300.20 17 107 7.8E-33 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 Pfam PF01327 Polypeptide deformylase 4 145 8.7E-47 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 149 3.2E-47 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 Gene3D G3DSA:3.90.45.10 1 168 6.0E-55 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 Hamap MF_00163 Peptide deformylase [def]. 2 160 29.986 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 PRINTS PR01576 Peptide deformylase signature 98 116 1.3E-35 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 PRINTS PR01576 Peptide deformylase signature 86 97 1.3E-35 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 PRINTS PR01576 Peptide deformylase signature 117 146 1.3E-35 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 PRINTS PR01576 Peptide deformylase signature 33 62 1.3E-35 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 SUPERFAMILY SSF56420 2 148 2.36E-54 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS07030 34da0afb1aa8be4e2dc67466a52252ed 169 PIRSF PIRSF004749 1 168 4.9E-48 T 29-03-2018 IPR023635 Peptide deformylase HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 SMART SM00304 318 370 8.2E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 SUPERFAMILY SSF158472 323 369 1.83E-6 T 29-03-2018 HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 488 597 1.5E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 Gene3D G3DSA:3.30.565.10 341 597 6.9E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 SUPERFAMILY SSF55874 475 596 1.83E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 Pfam PF06580 Histidine kinase 389 468 4.6E-21 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 SMART SM00387 483 598 3.2E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02285 48b48efd06e7744e401cd662d2349b7a 609 Pfam PF00672 HAMP domain 323 366 2.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS03845 ea2b1da7972b2ac50ac38df518d22ccc 323 SMART SM00306 124 218 1.8E-10 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03845 ea2b1da7972b2ac50ac38df518d22ccc 323 Gene3D G3DSA:2.170.16.10 122 318 7.2E-38 T 29-03-2018 HVS_RS03845 ea2b1da7972b2ac50ac38df518d22ccc 323 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 126 196 3.3E-6 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03845 ea2b1da7972b2ac50ac38df518d22ccc 323 SUPERFAMILY SSF51294 126 259 4.71E-26 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03845 ea2b1da7972b2ac50ac38df518d22ccc 323 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 237 261 0.0015 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS03845 ea2b1da7972b2ac50ac38df518d22ccc 323 Pfam PF07591 Pretoxin HINT domain 132 261 1.3E-29 T 29-03-2018 HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 Gene3D G3DSA:2.130.10.10 46 479 9.9E-79 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 Pfam PF15899 BNR-Asp box repeat 181 193 0.0088 T 29-03-2018 IPR002860 BNR repeat HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 Pfam PF15899 BNR-Asp box repeat 131 140 0.075 T 29-03-2018 IPR002860 BNR repeat HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 Gene3D G3DSA:1.10.1330.10 814 877 5.8E-4 T 29-03-2018 HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 SUPERFAMILY SSF110296 35 471 1.27E-74 T 29-03-2018 HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 SUPERFAMILY SSF63446 814 877 8.73E-14 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 Pfam PF02012 BNR/Asp-box repeat 249 259 0.034 T 29-03-2018 IPR002860 BNR repeat HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 SUPERFAMILY SSF110296 524 799 6.02E-34 T 29-03-2018 HVS_RS13810 b2ce459b798a249242f41481ca4464c6 877 Gene3D G3DSA:2.130.10.10 480 805 1.8E-52 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS06260 bd9c8ee4ec9917a97036b0d1c9571457 190 TIGRFAM TIGR00277 HDIG: HDIG domain 19 110 1.0E-7 T 29-03-2018 IPR006675 HDIG domain HVS_RS06260 bd9c8ee4ec9917a97036b0d1c9571457 190 SUPERFAMILY SSF109604 2 174 3.37E-34 T 29-03-2018 HVS_RS06260 bd9c8ee4ec9917a97036b0d1c9571457 190 SMART SM00471 14 142 1.4E-8 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS06260 bd9c8ee4ec9917a97036b0d1c9571457 190 Gene3D G3DSA:1.10.3210.10 1 188 9.8E-28 T 29-03-2018 HVS_RS06260 bd9c8ee4ec9917a97036b0d1c9571457 190 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 181 5.7E-50 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 HVS_RS06260 bd9c8ee4ec9917a97036b0d1c9571457 190 Pfam PF01966 HD domain 18 131 5.9E-16 T 29-03-2018 IPR006674 HD domain HVS_RS10015 8bb9d696d1fe3f596e1d499c092f0cd0 292 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 119 5.0E-26 T 29-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal HVS_RS10015 8bb9d696d1fe3f596e1d499c092f0cd0 292 Gene3D G3DSA:3.40.50.720 1 145 1.4E-6 T 29-03-2018 HVS_RS10015 8bb9d696d1fe3f596e1d499c092f0cd0 292 Gene3D G3DSA:3.40.50.720 147 289 1.1E-16 T 29-03-2018 HVS_RS10015 8bb9d696d1fe3f596e1d499c092f0cd0 292 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 143 240 3.3E-8 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HVS_RS10015 8bb9d696d1fe3f596e1d499c092f0cd0 292 SUPERFAMILY SSF51735 139 266 8.61E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09545 27551664f25563a0b04c49c2f8a5168f 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 18 360 1.4E-48 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS09545 27551664f25563a0b04c49c2f8a5168f 365 Pfam PF03845 Spore germination protein 13 323 3.8E-39 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 Gene3D G3DSA:3.30.70.1450 136 203 3.0E-6 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.7E-11 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.7E-11 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.7E-11 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.7E-11 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 Gene3D G3DSA:3.40.50.720 1 117 2.1E-26 T 29-03-2018 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 Pfam PF02254 TrkA-N domain 3 116 2.3E-27 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HVS_RS05500 350619da6a1344802a5da57461e92df9 204 SUPERFAMILY SSF51735 1 142 8.08E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 12 489 4.4E-173 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 331 357 2.9E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 146 159 2.9E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 222 239 2.9E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 256 2.9E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 170 198 2.9E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 SUPERFAMILY SSF51735 6 193 1.71E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 180 186 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 193 487 3.6E-108 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 PIRSF PIRSF000110 2 490 2.4E-165 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 15 190 2.1E-53 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 Gene3D G3DSA:3.30.360.10 192 490 1.1E-115 T 29-03-2018 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 Gene3D G3DSA:3.40.50.720 8 191 2.6E-58 T 29-03-2018 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 SUPERFAMILY SSF55347 185 488 2.32E-106 T 29-03-2018 HVS_RS15410 c501e34cceff2c3aadfd2237fc21e4ab 492 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 10 489 78.193 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 HVS_RS04155 bb8a06764000dcedcb7b5200b3522f7c 362 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 125 3.0E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HVS_RS04155 bb8a06764000dcedcb7b5200b3522f7c 362 SUPERFAMILY SSF55347 135 270 7.68E-21 T 29-03-2018 HVS_RS04155 bb8a06764000dcedcb7b5200b3522f7c 362 SUPERFAMILY SSF51735 2 153 3.26E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS04155 bb8a06764000dcedcb7b5200b3522f7c 362 Gene3D G3DSA:3.30.360.10 151 336 9.2E-28 T 29-03-2018 HVS_RS04155 bb8a06764000dcedcb7b5200b3522f7c 362 Gene3D G3DSA:3.40.50.720 1 150 1.4E-38 T 29-03-2018 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 Gene3D G3DSA:1.10.1330.10 435 503 1.2E-7 T 29-03-2018 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 SUPERFAMILY SSF53474 43 269 7.37E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 Gene3D G3DSA:2.60.120.260 298 427 2.9E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 Pfam PF00756 Putative esterase 58 205 5.0E-24 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 SUPERFAMILY SSF49785 297 424 1.31E-35 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 Gene3D G3DSA:3.40.50.1820 21 275 8.0E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 Pfam PF00404 Dockerin type I repeat 473 493 1.8E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 SMART SM00606 299 425 5.2E-47 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 473 492 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 Pfam PF03422 Carbohydrate binding module (family 6) 307 424 9.9E-32 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS00470 4257ad0e0dfafcca11e4aa4fc24fcd27 504 SUPERFAMILY SSF63446 435 501 9.16E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS10675 63033cc74b65b179ca7e1bc4fffa2c03 406 SUPERFAMILY SSF82171 84 390 1.44E-21 T 29-03-2018 HVS_RS10675 63033cc74b65b179ca7e1bc4fffa2c03 406 Gene3D G3DSA:2.140.10.30 295 400 5.7E-6 T 29-03-2018 HVS_RS10675 63033cc74b65b179ca7e1bc4fffa2c03 406 Gene3D G3DSA:2.140.10.30 4 294 1.8E-14 T 29-03-2018 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 PIRSF PIRSF000111 1 865 0.0 T 29-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 Gene3D G3DSA:3.40.50.1970 434 647 1.5E-54 T 29-03-2018 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 SUPERFAMILY SSF56796 452 864 6.15E-126 T 29-03-2018 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 636 664 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 Pfam PF00465 Iron-containing alcohol dehydrogenase 461 853 1.4E-121 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 Gene3D G3DSA:1.20.1090.10 648 865 5.8E-70 T 29-03-2018 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 SUPERFAMILY SSF53720 13 457 1.44E-74 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 Gene3D G3DSA:3.40.309.10 233 407 6.5E-25 T 29-03-2018 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 Pfam PF00171 Aldehyde dehydrogenase family 13 274 3.2E-19 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HVS_RS13905 ad8b6ec3c4eb109536a09e482b93f9b2 865 Gene3D G3DSA:3.40.605.10 6 232 3.5E-26 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HVS_RS09205 c93c7b14ee08ff1832566296b98ca861 123 Pfam PF02021 Uncharacterised protein family UPF0102 11 102 9.3E-27 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 HVS_RS09205 c93c7b14ee08ff1832566296b98ca861 123 Gene3D G3DSA:3.40.1350.10 10 123 8.9E-32 T 29-03-2018 HVS_RS09205 c93c7b14ee08ff1832566296b98ca861 123 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 5 113 7.6E-22 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 HVS_RS09205 c93c7b14ee08ff1832566296b98ca861 123 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 115 21.788 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 HVS_RS09205 c93c7b14ee08ff1832566296b98ca861 123 SUPERFAMILY SSF52980 11 108 5.27E-21 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HVS_RS08675 bf46897eaf7c13ae00391f2b82a4d1b1 173 PIRSF PIRSF021435 2 173 3.9E-48 T 29-03-2018 IPR014198 Stage III sporulation protein AB HVS_RS08675 bf46897eaf7c13ae00391f2b82a4d1b1 173 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 4 173 7.8E-50 T 29-03-2018 IPR014198 Stage III sporulation protein AB HVS_RS08675 bf46897eaf7c13ae00391f2b82a4d1b1 173 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 4 173 4.0E-53 T 29-03-2018 IPR014198 Stage III sporulation protein AB HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 204 215 - T 29-03-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 Pfam PF00457 Glycosyl hydrolases family 11 36 217 3.9E-68 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 114 124 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 SUPERFAMILY SSF49899 26 227 2.72E-84 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 PRINTS PR00911 Glycosyl hydrolase family 11 signature 189 197 1.0E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 PRINTS PR00911 Glycosyl hydrolase family 11 signature 104 113 1.0E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 PRINTS PR00911 Glycosyl hydrolase family 11 signature 166 175 1.0E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 PRINTS PR00911 Glycosyl hydrolase family 11 signature 114 124 1.0E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 PRINTS PR00911 Glycosyl hydrolase family 11 signature 161 166 1.0E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 PRINTS PR00911 Glycosyl hydrolase family 11 signature 141 147 1.0E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS12470 0f8abbb5355dc42388c7c040331f0900 305 Gene3D G3DSA:2.60.120.180 20 225 1.3E-87 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PIRSF PIRSF000099 8 431 9.9E-182 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 231 263 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 34 428 1.2E-171 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 429 43.745 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 Pfam PF00815 Histidinol dehydrogenase 22 429 3.1E-179 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 322 347 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 253 272 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 34 58 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 231 252 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 363 381 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 172 198 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 PRINTS PR00083 Histidinol dehydrogenase signature 202 227 1.4E-90 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 Gene3D G3DSA:3.40.50.1980 28 227 4.1E-89 T 29-03-2018 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 SUPERFAMILY SSF53720 28 429 4.32E-86 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HVS_RS15265 1562d1a7e40c2b87c9148a84d3e8e334 431 Gene3D G3DSA:3.40.50.1980 228 373 5.5E-69 T 29-03-2018 HVS_RS05420 c4afb7a3cb4fb29c098ee522f608b6de 270 Pfam PF02163 Peptidase family M50 90 142 7.6E-9 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 HVS_RS05420 c4afb7a3cb4fb29c098ee522f608b6de 270 SUPERFAMILY SSF54631 205 251 5.94E-6 T 29-03-2018 HVS_RS05420 c4afb7a3cb4fb29c098ee522f608b6de 270 Gene3D G3DSA:3.10.580.10 27 254 1.6E-5 T 29-03-2018 HVS_RS02390 49d537ffb4570694473f709940eee41a 229 Gene3D G3DSA:3.40.50.2300 2 181 1.2E-21 T 29-03-2018 HVS_RS02390 49d537ffb4570694473f709940eee41a 229 SUPERFAMILY SSF52172 10 151 5.98E-20 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS02390 49d537ffb4570694473f709940eee41a 229 SMART SM00448 9 129 2.2E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02390 49d537ffb4570694473f709940eee41a 229 Pfam PF00072 Response regulator receiver domain 11 129 1.1E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS07305 5822e2a0c7d05df9f627ded5befe7450 272 Gene3D G3DSA:3.40.50.620 1 267 1.3E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS07305 5822e2a0c7d05df9f627ded5befe7450 272 Pfam PF01171 PP-loop family 19 127 1.7E-5 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 HVS_RS07305 5822e2a0c7d05df9f627ded5befe7450 272 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 261 3.1E-78 T 29-03-2018 IPR005232 Lactate racemization operon protein LarE HVS_RS07305 5822e2a0c7d05df9f627ded5befe7450 272 PIRSF PIRSF006661 1 272 8.5E-101 T 29-03-2018 IPR005232 Lactate racemization operon protein LarE HVS_RS07305 5822e2a0c7d05df9f627ded5befe7450 272 SUPERFAMILY SSF52402 15 219 2.65E-37 T 29-03-2018 HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 Gene3D G3DSA:1.10.10.10 18 114 5.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 SMART SM00347 23 123 4.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 2.5E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 2.5E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 2.5E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 Pfam PF01047 MarR family 31 87 1.7E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site HVS_RS05900 524378083c4e20dc662d0fbb42272ba1 144 SUPERFAMILY SSF46785 12 138 4.61E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS01705 ca7cdcaf938038d2c71c647b57373554 242 Pfam PF00188 Cysteine-rich secretory protein family 124 237 2.3E-6 T 29-03-2018 IPR014044 CAP domain HVS_RS01705 ca7cdcaf938038d2c71c647b57373554 242 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 75 94 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS01705 ca7cdcaf938038d2c71c647b57373554 242 SUPERFAMILY SSF55797 117 239 3.14E-6 T 29-03-2018 IPR014044 CAP domain HVS_RS01705 ca7cdcaf938038d2c71c647b57373554 242 Pfam PF00404 Dockerin type I repeat 42 62 1.3E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS01705 ca7cdcaf938038d2c71c647b57373554 242 Gene3D G3DSA:3.40.33.10 112 220 6.6E-4 T 29-03-2018 IPR014044 CAP domain HVS_RS01705 ca7cdcaf938038d2c71c647b57373554 242 SUPERFAMILY SSF63446 37 105 5.89E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07325 18de2666e9c175f5206f819dab60d819 414 SUPERFAMILY SSF53756 14 373 3.68E-68 T 29-03-2018 HVS_RS07325 18de2666e9c175f5206f819dab60d819 414 Pfam PF00534 Glycosyl transferases group 1 188 357 5.0E-37 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS07325 18de2666e9c175f5206f819dab60d819 414 Pfam PF13439 Glycosyltransferase Family 4 22 168 4.4E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS07325 18de2666e9c175f5206f819dab60d819 414 Gene3D G3DSA:3.40.50.2000 152 375 7.8E-46 T 29-03-2018 HVS_RS10185 bb08e52a4614302c94b8d0d2f68db6de 174 Pfam PF04347 Flagellar biosynthesis protein, FliO 22 107 4.8E-12 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 HVS_RS10185 bb08e52a4614302c94b8d0d2f68db6de 174 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 11 80 5.2E-16 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 HVS_RS15235 6983137194bddbf1871c97325055aa2d 385 Pfam PF04326 Putative DNA-binding domain 14 133 1.7E-22 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 Gene3D G3DSA:3.40.640.10 9 286 2.7E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 SUPERFAMILY SSF53383 9 386 7.1E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 223 237 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 SUPERFAMILY SSF55904 345 483 3.4E-37 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 9 371 7.6E-80 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 376 470 1.5E-11 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HVS_RS14200 2732f70375e0e99c1a9d3db13997ccb1 485 Gene3D G3DSA:3.90.100.10 374 484 5.2E-31 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 ProSitePatterns PS00018 EF-hand calcium-binding domain. 122 134 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 PIRSF PIRSF005572 2 376 3.4E-118 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 Gene3D G3DSA:3.40.640.10 14 241 1.9E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 SUPERFAMILY SSF53383 5 372 4.76E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 Gene3D G3DSA:3.90.1150.10 242 371 9.0E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS07455 e21c7b2131597b67870087534da2a5af 386 Pfam PF00266 Aminotransferase class-V 5 362 3.6E-79 T 29-03-2018 IPR000192 Aminotransferase class V domain HVS_RS08415 49cf3d56282ebfacc2c9f66823dba078 313 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 300 30.45 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HVS_RS08415 49cf3d56282ebfacc2c9f66823dba078 313 Gene3D G3DSA:3.40.50.300 1 194 1.4E-65 T 29-03-2018 HVS_RS08415 49cf3d56282ebfacc2c9f66823dba078 313 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 4 289 4.7E-98 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HVS_RS08415 49cf3d56282ebfacc2c9f66823dba078 313 SUPERFAMILY SSF52540 5 157 1.9E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08415 49cf3d56282ebfacc2c9f66823dba078 313 Gene3D G3DSA:1.10.287.890 199 280 2.1E-26 T 29-03-2018 HVS_RS08415 49cf3d56282ebfacc2c9f66823dba078 313 Pfam PF01715 IPP transferase 37 283 1.8E-82 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 427 44.449 T 29-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 Gene3D G3DSA:3.20.20.140 74 369 1.6E-58 T 29-03-2018 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 Pfam PF01979 Amidohydrolase family 55 401 1.9E-67 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 Gene3D G3DSA:2.30.40.10 2 73 2.1E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 SUPERFAMILY SSF51338 2 58 2.05E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 SUPERFAMILY SSF51338 352 426 2.05E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS12225 2fed2fea2101c4c290cd472df75c0d99 428 SUPERFAMILY SSF51556 58 352 6.53E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS00035 ae7b64b43f9c4240c5f0a023af0e9470 260 PIRSF PIRSF009320 88 259 2.2E-9 T 29-03-2018 HVS_RS00035 ae7b64b43f9c4240c5f0a023af0e9470 260 PIRSF PIRSF009320 2 94 3.7E-16 T 29-03-2018 HVS_RS00035 ae7b64b43f9c4240c5f0a023af0e9470 260 Pfam PF13614 AAA domain 2 178 1.5E-71 T 29-03-2018 IPR025669 AAA domain HVS_RS00035 ae7b64b43f9c4240c5f0a023af0e9470 260 Gene3D G3DSA:3.40.50.300 1 259 1.1E-66 T 29-03-2018 HVS_RS00035 ae7b64b43f9c4240c5f0a023af0e9470 260 SUPERFAMILY SSF52540 1 254 4.42E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 112 3.8E-27 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 115 248 1.9E-45 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 SUPERFAMILY SSF55347 114 221 3.05E-33 T 29-03-2018 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 Gene3D G3DSA:3.40.50.720 1 127 5.1E-26 T 29-03-2018 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 Gene3D G3DSA:3.30.360.10 128 219 6.7E-36 T 29-03-2018 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 PIRSF PIRSF000161 1 252 3.1E-81 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 SUPERFAMILY SSF51735 221 249 5.21E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 SUPERFAMILY SSF51735 1 113 5.21E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 249 1.1E-63 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 137 154 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS08985 7eb9af2b62a4585ce8ff9bbaa6ec25e6 252 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 250 30.561 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SUPERFAMILY SSF63446 880 947 1.28E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 918 937 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Pfam PF00942 Cellulose binding domain 547 634 2.6E-13 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Pfam PF00942 Cellulose binding domain 727 808 5.5E-19 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SUPERFAMILY SSF49384 724 872 1.78E-43 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Gene3D G3DSA:2.60.40.710 542 698 3.1E-37 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SMART SM01067 727 809 1.7E-23 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SMART SM01067 544 635 0.0012 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SUPERFAMILY SSF49384 542 699 5.76E-39 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Gene3D G3DSA:1.10.1330.10 880 948 0.026 T 29-03-2018 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 443 459 - T 29-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SUPERFAMILY SSF48208 39 76 7.37E-124 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 SUPERFAMILY SSF48208 108 525 7.37E-124 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Gene3D G3DSA:1.50.10.10 40 524 2.9E-118 T 29-03-2018 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Pfam PF00759 Glycosyl hydrolase family 9 45 517 8.0E-110 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Gene3D G3DSA:2.60.40.710 713 878 5.0E-46 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS04935 73087894ad813dfe4181a17fd461df3c 948 Pfam PF00404 Dockerin type I repeat 884 904 7.0E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS01210 61e45c9115f5c3c06b1177ab129b3e7f 289 SUPERFAMILY SSF53448 3 273 1.92E-69 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01210 61e45c9115f5c3c06b1177ab129b3e7f 289 Gene3D G3DSA:3.90.550.10 2 289 9.4E-65 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01210 61e45c9115f5c3c06b1177ab129b3e7f 289 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 3.2E-126 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 HVS_RS01210 61e45c9115f5c3c06b1177ab129b3e7f 289 Pfam PF00483 Nucleotidyl transferase 5 264 3.3E-34 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS10240 b408eec123e08deb471cb6e65f739656 151 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 9 146 8.7E-28 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 HVS_RS10240 b408eec123e08deb471cb6e65f739656 151 Pfam PF02050 Flagellar FliJ protein 25 146 2.1E-20 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 HVS_RS04020 b7aafbd2e2ddb3ac2c4b23f5000b05c7 184 SUPERFAMILY SSF51294 6 82 1.71E-16 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04020 b7aafbd2e2ddb3ac2c4b23f5000b05c7 184 Pfam PF15529 Bacterial toxin 24 92 152 5.7E-8 T 29-03-2018 IPR029114 Bacterial toxin 24 HVS_RS04020 b7aafbd2e2ddb3ac2c4b23f5000b05c7 184 Pfam PF07591 Pretoxin HINT domain 5 82 3.3E-18 T 29-03-2018 HVS_RS04020 b7aafbd2e2ddb3ac2c4b23f5000b05c7 184 Gene3D G3DSA:2.170.16.10 2 83 1.8E-19 T 29-03-2018 HVS_RS04020 b7aafbd2e2ddb3ac2c4b23f5000b05c7 184 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 58 81 0.0015 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.2E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 SUPERFAMILY SSF47729 1 90 2.06E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 SMART SM00411 1 90 4.5E-44 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS00560 ad85c68f352a6a6686c6423645e55299 91 Gene3D G3DSA:4.10.520.10 1 91 2.7E-36 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HVS_RS10450 495411b776997258c430a90faee96dcc 479 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 477 1.2E-161 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Gene3D G3DSA:3.90.190.20 329 479 9.9E-49 T 29-03-2018 HVS_RS10450 495411b776997258c430a90faee96dcc 479 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 106 129 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Gene3D G3DSA:3.40.1390.10 1 98 2.4E-28 T 29-03-2018 HVS_RS10450 495411b776997258c430a90faee96dcc 479 SUPERFAMILY SSF53623 99 321 6.93E-70 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Gene3D G3DSA:3.40.1190.10 99 328 1.7E-61 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Pfam PF08245 Mur ligase middle domain 108 304 4.7E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 477 35.304 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 HVS_RS10450 495411b776997258c430a90faee96dcc 479 SUPERFAMILY SSF63418 1 98 5.36E-23 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Pfam PF01225 Mur ligase family, catalytic domain 23 96 1.2E-9 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 HVS_RS10450 495411b776997258c430a90faee96dcc 479 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 409 5.6E-25 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS10450 495411b776997258c430a90faee96dcc 479 SUPERFAMILY SSF53244 324 478 6.8E-51 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS11240 96d1915565a51f29dbe385888b603489 226 Gene3D G3DSA:1.10.260.40 158 226 0.47 T 29-03-2018 HVS_RS11240 96d1915565a51f29dbe385888b603489 226 SUPERFAMILY SSF47413 1 66 6.17E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS11240 96d1915565a51f29dbe385888b603489 226 Gene3D G3DSA:1.10.260.40 95 157 0.2 T 29-03-2018 HVS_RS11240 96d1915565a51f29dbe385888b603489 226 SMART SM00530 6 61 1.7E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS11240 96d1915565a51f29dbe385888b603489 226 Gene3D G3DSA:1.10.260.40 1 94 1.3E-23 T 29-03-2018 HVS_RS11240 96d1915565a51f29dbe385888b603489 226 Pfam PF01381 Helix-turn-helix 7 61 1.4E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS15485 106e272cf4a99a3d433dd44fba476a58 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 416 1.2E-176 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS15485 106e272cf4a99a3d433dd44fba476a58 422 Gene3D G3DSA:3.65.10.10 221 420 1.7E-50 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS15485 106e272cf4a99a3d433dd44fba476a58 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.832 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS15485 106e272cf4a99a3d433dd44fba476a58 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 407 1.2E-106 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS15485 106e272cf4a99a3d433dd44fba476a58 422 Gene3D G3DSA:3.65.10.10 21 220 3.1E-50 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS15485 106e272cf4a99a3d433dd44fba476a58 422 SUPERFAMILY SSF55205 3 419 2.71E-139 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 SUPERFAMILY SSF53335 2 301 7.96E-62 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 326 387 1.7E-20 T 29-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 98 299 4.9E-48 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 173 184 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 92 3.1E-34 T 29-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 407 452 6.2E-17 T 29-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 107 117 8.8E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 78 92 8.8E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 284 301 8.8E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 240 8.8E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 186 8.8E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 Gene3D G3DSA:3.30.70.1170 23 87 6.8E-22 T 29-03-2018 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 35 301 1.8E-69 T 29-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 HVS_RS12150 98b335ddee7db909f6608260f01f727a 454 Gene3D G3DSA:3.40.50.150 88 310 1.1E-56 T 29-03-2018 HVS_RS09150 8976dfa23fe0f5f4adb2edae627e15eb 312 Pfam PF13732 Domain of unknown function (DUF4162) 214 303 4.3E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 HVS_RS09150 8976dfa23fe0f5f4adb2edae627e15eb 312 SMART SM00382 26 208 2.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS09150 8976dfa23fe0f5f4adb2edae627e15eb 312 Pfam PF00005 ABC transporter 17 160 6.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS09150 8976dfa23fe0f5f4adb2edae627e15eb 312 Gene3D G3DSA:3.40.50.300 1 273 4.2E-65 T 29-03-2018 HVS_RS09150 8976dfa23fe0f5f4adb2edae627e15eb 312 SUPERFAMILY SSF52540 2 224 1.81E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00690 febc0b31ad1eb357d2eb221c6d5dbdf7 276 SUPERFAMILY SSF52540 30 245 3.63E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00690 febc0b31ad1eb357d2eb221c6d5dbdf7 276 Hamap MF_02040 Iron-sulfur cluster carrier protein. 24 270 34.872 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein HVS_RS00690 febc0b31ad1eb357d2eb221c6d5dbdf7 276 ProSitePatterns PS01215 Mrp family signature. 137 153 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 HVS_RS00690 febc0b31ad1eb357d2eb221c6d5dbdf7 276 Gene3D G3DSA:3.40.50.300 21 249 2.7E-53 T 29-03-2018 HVS_RS00690 febc0b31ad1eb357d2eb221c6d5dbdf7 276 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 269 1.1E-90 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 HVS_RS07290 2ea0b5866d4d0ae9b4f9f5ca5ad2ee42 257 PIRSF PIRSF004789 1 256 5.1E-97 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like HVS_RS07290 2ea0b5866d4d0ae9b4f9f5ca5ad2ee42 257 Gene3D G3DSA:3.60.21.10 1 256 2.8E-47 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS07290 2ea0b5866d4d0ae9b4f9f5ca5ad2ee42 257 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 2 254 5.8E-88 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like HVS_RS07290 2ea0b5866d4d0ae9b4f9f5ca5ad2ee42 257 SUPERFAMILY SSF56300 1 252 1.52E-84 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS07290 2ea0b5866d4d0ae9b4f9f5ca5ad2ee42 257 Pfam PF13277 YmdB-like protein 4 251 4.4E-106 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like HVS_RS14495 daadfd1e9dac218dc01839fb868c7c89 167 SUPERFAMILY SSF54637 16 165 4.52E-50 T 29-03-2018 IPR029069 HotDog domain HVS_RS14495 daadfd1e9dac218dc01839fb868c7c89 167 Pfam PF03061 Thioesterase superfamily 37 110 1.5E-18 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HVS_RS14495 daadfd1e9dac218dc01839fb868c7c89 167 Gene3D G3DSA:3.10.129.10 2 167 4.0E-51 T 29-03-2018 HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 SUPERFAMILY SSF55658 1 57 2.96E-19 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.484 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.1E-24 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 Gene3D G3DSA:3.10.430.100 63 147 6.7E-31 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 1.9E-29 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 Gene3D G3DSA:3.40.5.10 1 49 4.3E-24 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 3.0E-49 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01310 96e9e8b7caef7abe67adc0bcbe95b0c0 151 SUPERFAMILY SSF55653 56 147 1.05E-26 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 SUPERFAMILY SSF53697 4 446 1.7E-147 T 29-03-2018 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 Gene3D G3DSA:3.40.50.10490 1 62 1.9E-11 T 29-03-2018 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 Gene3D G3DSA:3.40.50.10490 208 434 2.5E-74 T 29-03-2018 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 25.938 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 Gene3D G3DSA:3.40.50.10490 63 207 7.8E-48 T 29-03-2018 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 Pfam PF00342 Phosphoglucose isomerase 76 426 1.8E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 1.9E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 1.9E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 1.9E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 1.9E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 1.9E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 1.9E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11350 18e74987929ebddcf6f096bb873c6bd2 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS15045 fcf9c6c3d8d5adc3519e06c6108e02de 146 SUPERFAMILY SSF52080 5 145 5.1E-50 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P HVS_RS15045 fcf9c6c3d8d5adc3519e06c6108e02de 146 Gene3D G3DSA:3.100.10.10 42 146 6.4E-35 T 29-03-2018 HVS_RS15045 fcf9c6c3d8d5adc3519e06c6108e02de 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 4.3E-38 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P HVS_RS15045 fcf9c6c3d8d5adc3519e06c6108e02de 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 1.9E-52 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15045 fcf9c6c3d8d5adc3519e06c6108e02de 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.314 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 HVS_RS15045 fcf9c6c3d8d5adc3519e06c6108e02de 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 PIRSF PIRSF000728 9 287 7.0E-111 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 Hamap MF_00082_B Acetylglutamate kinase [argB]. 22 287 36.678 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 TIGRFAM TIGR00761 argB: acetylglutamate kinase 25 262 3.3E-78 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 Hamap MF_00082_A Acetylglutamate kinase [argB]. 25 272 29.98 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 Gene3D G3DSA:3.40.1160.10 1 293 3.3E-75 T 29-03-2018 HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 SUPERFAMILY SSF53633 3 288 7.33E-95 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS14365 84eb6a0658e59561db8dac78fcca2e64 298 Pfam PF00696 Amino acid kinase family 24 264 5.5E-48 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 Gene3D G3DSA:3.40.50.300 437 663 7.7E-14 T 29-03-2018 HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 421 727 6.4E-71 T 29-03-2018 IPR006500 DNA primase, phage/plasmid HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 SMART SM00885 320 471 3.5E-43 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 Pfam PF03288 Poxvirus D5 protein-like 682 738 1.0E-7 T 29-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 SUPERFAMILY SSF52540 463 660 1.01E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 Pfam PF08706 D5 N terminal like 322 470 1.8E-20 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS15885 4dfe83233198207a0c2bf35c6f2ea9c3 767 Gene3D G3DSA:1.10.10.10 689 756 1.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 SUPERFAMILY SSF55931 4 295 3.79E-123 T 29-03-2018 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 2.2E-185 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 Pfam PF02637 GatB domain 327 474 1.5E-56 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 Pfam PF02934 GatB/GatE catalytic domain 5 287 1.2E-114 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 SUPERFAMILY SSF89095 296 402 1.13E-34 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 SMART SM00845 327 474 3.7E-79 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 Gene3D G3DSA:1.10.10.410 414 475 4.6E-25 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal HVS_RS07245 2fa4dc7145a65527f095c93949386a26 479 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 39.311 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 Gene3D G3DSA:2.20.28.10 1 51 1.3E-29 T 29-03-2018 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 PRINTS PR00163 Rubredoxin signature 3 19 3.2E-13 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 PRINTS PR00163 Rubredoxin signature 33 49 3.2E-13 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 PIRSF PIRSF000071 1 52 5.2E-29 T 29-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 Pfam PF00301 Rubredoxin 3 49 3.3E-26 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 HVS_RS00630 4d283b7f2c34aeae1b841568a51e28cb 52 SUPERFAMILY SSF57802 1 51 7.91E-25 T 29-03-2018 HVS_RS10970 315fdda788868abb0054708a04f6b50f 191 SUPERFAMILY SSF100950 3 190 1.53E-49 T 29-03-2018 HVS_RS10970 315fdda788868abb0054708a04f6b50f 191 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 186 7.0E-52 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HVS_RS10970 315fdda788868abb0054708a04f6b50f 191 Gene3D G3DSA:3.40.50.10420 1 191 6.8E-54 T 29-03-2018 HVS_RS10970 315fdda788868abb0054708a04f6b50f 191 PIRSF PIRSF006806 1 189 2.2E-52 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HVS_RS10970 315fdda788868abb0054708a04f6b50f 191 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 186 2.1E-47 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 154 165 - T 29-03-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 SUPERFAMILY SSF49785 208 333 4.76E-33 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 SMART SM00606 207 335 7.9E-49 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 Pfam PF03422 Carbohydrate binding module (family 6) 215 334 3.4E-33 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 PRINTS PR00911 Glycosyl hydrolase family 11 signature 54 63 4.3E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 PRINTS PR00911 Glycosyl hydrolase family 11 signature 64 74 4.3E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 PRINTS PR00911 Glycosyl hydrolase family 11 signature 116 125 4.3E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 PRINTS PR00911 Glycosyl hydrolase family 11 signature 91 97 4.3E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 PRINTS PR00911 Glycosyl hydrolase family 11 signature 139 147 4.3E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 PRINTS PR00911 Glycosyl hydrolase family 11 signature 111 116 4.3E-17 T 29-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 SUPERFAMILY SSF63446 345 403 9.22E-14 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 Pfam PF00457 Glycosyl hydrolases family 11 4 167 1.5E-62 T 29-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 SUPERFAMILY SSF49899 1 177 2.6E-75 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 Gene3D G3DSA:1.10.1330.10 342 406 5.9E-6 T 29-03-2018 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 Pfam PF00404 Dockerin type I repeat 380 400 2.3E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 ProSitePatterns PS00018 EF-hand calcium-binding domain. 346 358 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 Gene3D G3DSA:2.60.120.180 1 175 6.0E-76 T 29-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 Gene3D G3DSA:2.60.120.260 204 338 1.3E-28 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 64 74 - T 29-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 HVS_RS09075 f480dbcefb2e10cfb9c7f7a2e9c9b93c 406 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 380 399 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS00780 e81e5d04a2b49a02fb7c6dcbbe15124b 564 Gene3D G3DSA:1.10.10.10 499 564 1.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00780 e81e5d04a2b49a02fb7c6dcbbe15124b 564 Gene3D G3DSA:1.10.10.10 407 498 0.0039 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00780 e81e5d04a2b49a02fb7c6dcbbe15124b 564 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 314 398 5.5E-14 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain HVS_RS00780 e81e5d04a2b49a02fb7c6dcbbe15124b 564 Pfam PF04326 Putative DNA-binding domain 23 144 2.2E-13 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 HVS_RS12615 aecdff5564f87dcc14b74ea0f9c423d0 382 Pfam PF00149 Calcineurin-like phosphoesterase 156 325 8.5E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HVS_RS12615 aecdff5564f87dcc14b74ea0f9c423d0 382 SUPERFAMILY SSF56300 156 379 1.57E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS12615 aecdff5564f87dcc14b74ea0f9c423d0 382 Gene3D G3DSA:3.60.21.10 156 370 5.7E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 Gene3D G3DSA:2.30.30.40 151 213 0.028 T 29-03-2018 HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 Gene3D G3DSA:2.30.30.40 71 148 4.8E-9 T 29-03-2018 HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 Pfam PF08239 Bacterial SH3 domain 94 132 9.2E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 Pfam PF13457 SH3-like domain 185 203 7.3 T 29-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 Pfam PF00877 NlpC/P60 family 232 339 5.6E-10 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 Gene3D G3DSA:3.90.1720.10 214 352 8.2E-18 T 29-03-2018 HVS_RS00210 c37f5dedaa9a721450c54da79b7f8e50 356 SUPERFAMILY SSF54001 212 344 1.42E-19 T 29-03-2018 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 SUPERFAMILY SSF103263 4 378 4.06E-116 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 Gene3D G3DSA:3.60.150.10 3 390 6.2E-134 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 Pfam PF01264 Chorismate synthase 36 373 2.9E-114 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 ProSitePatterns PS00788 Chorismate synthase signature 2. 143 159 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 PIRSF PIRSF001456 3 389 2.4E-121 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 Hamap MF_00300 Chorismate synthase [aroC]. 10 381 34.225 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS07995 782532765e19ef816f918ca43c75ebba 393 TIGRFAM TIGR00033 aroC: chorismate synthase 37 376 6.0E-114 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 29.835 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 7.2E-66 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 Gene3D G3DSA:3.90.1180.10 1 144 3.4E-67 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 SUPERFAMILY SSF52161 1 140 1.7E-63 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 Pfam PF00572 Ribosomal protein L13 14 138 2.0E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HVS_RS02765 75bbb5e8b4f3cd7386be89856fc81583 144 PIRSF PIRSF002181 1 143 2.2E-54 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 Pfam PF00535 Glycosyl transferase family 2 5 148 1.6E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 Gene3D G3DSA:1.25.40.10 236 279 3.8E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 Gene3D G3DSA:1.25.40.10 280 358 3.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 Pfam PF13181 Tetratricopeptide repeat 197 217 0.1 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 Pfam PF13181 Tetratricopeptide repeat 262 292 0.018 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 SMART SM00028 262 295 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 SMART SM00028 190 223 65.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 SMART SM00028 308 341 41.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 SUPERFAMILY SSF81901 178 345 9.68E-15 T 29-03-2018 HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 SUPERFAMILY SSF53448 3 147 5.38E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09940 2a72e098eab13db1eab712a549b9cf7d 361 Gene3D G3DSA:3.90.550.10 2 235 8.7E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 SUPERFAMILY SSF88723 3 64 2.16E-12 T 29-03-2018 IPR029060 PIN domain-like HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 SUPERFAMILY SSF88723 93 139 2.16E-12 T 29-03-2018 IPR029060 PIN domain-like HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 Pfam PF02562 PhoH-like protein 234 452 2.2E-49 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 Gene3D G3DSA:3.40.50.1010 1 174 6.0E-40 T 29-03-2018 IPR029060 PIN domain-like HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 SUPERFAMILY SSF52540 233 333 2.92E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 SUPERFAMILY SSF52540 361 425 2.92E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 SMART SM00670 3 128 6.7E-13 T 29-03-2018 IPR002716 PIN domain HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 Pfam PF13638 PIN domain 5 140 5.4E-34 T 29-03-2018 IPR002716 PIN domain HVS_RS11025 0eba64bbbdcdd7e1d57f969eee970a4f 459 Gene3D G3DSA:3.40.50.300 240 450 4.5E-22 T 29-03-2018 HVS_RS11390 ee5f1cae817309c91f998a5b23a8ed5d 453 SUPERFAMILY SSF64182 2 131 1.92E-30 T 29-03-2018 HVS_RS11390 ee5f1cae817309c91f998a5b23a8ed5d 453 Pfam PF02272 DHHA1 domain 8 128 6.3E-23 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HVS_RS01665 736fdd71903a737cf07718736135a683 337 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 10 331 1.0E-104 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HVS_RS01665 736fdd71903a737cf07718736135a683 337 Pfam PF03116 NQR2, RnfD, RnfE family 7 331 5.0E-119 T 29-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 HVS_RS01665 736fdd71903a737cf07718736135a683 337 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 5 333 25.122 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 HVS_RS15025 d69bfa985c066fe9ddb1585cc9111e5e 92 SUPERFAMILY SSF50104 3 60 9.93E-14 T 29-03-2018 IPR008991 Translation protein SH3-like domain HVS_RS15025 d69bfa985c066fe9ddb1585cc9111e5e 92 Gene3D G3DSA:2.30.30.30 2 91 9.9E-14 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 HVS_RS11615 e17f2e5b7e0c15a4bcea97f4ff09ca31 75 Pfam PF00381 PTS HPr component phosphorylation site 16 64 3.2E-6 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS11615 e17f2e5b7e0c15a4bcea97f4ff09ca31 75 SUPERFAMILY SSF55594 16 65 2.49E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS11615 e17f2e5b7e0c15a4bcea97f4ff09ca31 75 Gene3D G3DSA:3.30.1340.10 1 75 3.2E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS13990 a2f45cc6b1c30a688080b159e0d5a8c0 247 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 232 1.9E-48 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 HVS_RS13990 a2f45cc6b1c30a688080b159e0d5a8c0 247 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 3 241 57.937 T 29-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 HVS_RS13990 a2f45cc6b1c30a688080b159e0d5a8c0 247 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 61 227 2.6E-61 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.47.10 2 309 2.3E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.47.10 979 1340 1.2E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.50.720 2066 2349 1.3E-35 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF14765 Polyketide synthase dehydratase 2385 2460 9.5E-7 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF14765 Polyketide synthase dehydratase 2550 2657 4.4E-8 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SMART SM00825 Beta-ketoacyl synthase 11 478 5.3E-61 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1233 1249 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.47.10 313 476 1.1E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF53901 5 135 3.04E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF53901 195 421 3.04E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 306 424 8.6E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2073 2301 4.6E-11 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF53901 1216 1486 7.48E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF53901 1090 1115 7.48E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF08659 KR domain 2075 2300 3.8E-31 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.30.70.250 756 802 6.4E-15 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF47336 1713 1786 2.26E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF00698 Acyl transferase domain 617 941 5.4E-30 T 29-03-2018 IPR014043 Acyl transferase HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF55048 747 811 2.49E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:1.10.1200.10 1710 1798 5.1E-11 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:1.10.1200.10 1590 1677 1.4E-9 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF47336 1591 1665 5.55E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 298 4.4E-47 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1217 1327 2.3E-14 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 618 922 2.1E-33 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.366.10 614 755 2.6E-29 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.366.10 803 930 8.1E-21 T 29-03-2018 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 Gene3D G3DSA:3.40.47.10 1361 1502 1.3E-9 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF51735 2075 2114 7.86E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF51735 2158 2353 7.86E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF52151 615 746 2.01E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HVS_RS12010 ebe4f004db3c495085d24404e41c28cf 2659 SUPERFAMILY SSF52151 812 918 2.01E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HVS_RS14045 38f4d28fc8c3c323d43d51205578e192 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 154 4.3E-11 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS14045 38f4d28fc8c3c323d43d51205578e192 193 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 128 156 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 HVS_RS14045 38f4d28fc8c3c323d43d51205578e192 193 Gene3D G3DSA:2.160.10.10 23 188 2.6E-43 T 29-03-2018 HVS_RS14045 38f4d28fc8c3c323d43d51205578e192 193 SUPERFAMILY SSF51161 33 176 6.1E-45 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 SUPERFAMILY SSF55826 220 237 5.36E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 SUPERFAMILY SSF55826 266 395 5.36E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Gene3D G3DSA:3.40.50.800 465 579 6.9E-30 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 SUPERFAMILY SSF52954 469 574 6.8E-30 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 465 5.1E-50 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.6E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.6E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.6E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.6E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Pfam PF04073 Aminoacyl-tRNA editing domain 268 381 2.3E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Gene3D G3DSA:3.30.930.10 2 267 1.1E-72 T 29-03-2018 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Gene3D G3DSA:3.30.930.10 393 464 9.0E-9 T 29-03-2018 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Gene3D G3DSA:3.90.960.10 268 392 3.5E-42 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 575 41.12 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 SUPERFAMILY SSF55681 9 237 2.66E-97 T 29-03-2018 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 SUPERFAMILY SSF55681 413 484 2.66E-97 T 29-03-2018 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 PIRSF PIRSF001535 1 578 2.0E-263 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 569 3.7E-216 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HVS_RS14235 ff6202333d4dccf38ea29234bf9883f9 580 Pfam PF03129 Anticodon binding domain 481 571 1.1E-19 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Gene3D G3DSA:3.30.565.10 22 225 3.4E-72 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 7 641 94.512 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 10 641 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 366 380 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 10 20 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 594 606 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 199 212 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 610 626 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 380 400 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 184 199 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 318 334 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 225 247 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 248 266 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR01159 DNA gyrase subunit B signature 476 485 3.7E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 630 2.2E-31 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 SMART SM00387 35 179 7.4E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 SUPERFAMILY SSF54211 226 397 6.64E-57 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 178 7.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 SUPERFAMILY SSF56719 400 634 1.78E-91 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 SMART SM00433 39 634 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Pfam PF00204 DNA gyrase B 226 396 4.4E-63 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Pfam PF01751 Toprim domain 425 536 1.2E-18 T 29-03-2018 IPR006171 TOPRIM domain HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 492 508 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 510 527 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 530 542 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 39 54 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 573 589 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 426 440 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 74 87 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 275 288 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 PRINTS PR00418 DNA topoisomerase II family signature 117 131 7.9E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Gene3D G3DSA:3.40.50.670 406 638 4.1E-103 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 SUPERFAMILY SSF55874 10 215 3.37E-71 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS00030 8f1972ccf4483c5efbee677f592c8177 641 Gene3D G3DSA:3.30.230.10 226 398 3.7E-63 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS15135 e9f17fe403def82108152d2a0e135c6b 207 SUPERFAMILY SSF52166 1 206 4.19E-82 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HVS_RS15135 e9f17fe403def82108152d2a0e135c6b 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.126 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15135 e9f17fe403def82108152d2a0e135c6b 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 7.9E-80 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15135 e9f17fe403def82108152d2a0e135c6b 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.6E-71 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 HVS_RS15135 e9f17fe403def82108152d2a0e135c6b 207 Gene3D G3DSA:3.40.1370.10 147 205 3.2E-15 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HVS_RS15135 e9f17fe403def82108152d2a0e135c6b 207 Gene3D G3DSA:3.40.1370.10 2 146 7.0E-60 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HVS_RS07470 c8f05039dbcd86bb1fab6ecf26c3393d 223 SUPERFAMILY SSF48452 97 216 3.41E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS07470 c8f05039dbcd86bb1fab6ecf26c3393d 223 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 5 215 1.9E-73 T 29-03-2018 IPR018708 Protein of unknown function DUF2225 HVS_RS07470 c8f05039dbcd86bb1fab6ecf26c3393d 223 Gene3D G3DSA:1.25.40.10 3 223 3.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS06435 a4cb9f23b6e2e6d0b0f839ba3279c578 226 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 33 200 7.1E-73 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 HVS_RS06435 a4cb9f23b6e2e6d0b0f839ba3279c578 226 SUPERFAMILY SSF55729 3 222 1.48E-89 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS06435 a4cb9f23b6e2e6d0b0f839ba3279c578 226 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 30 210 1.0E-65 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 HVS_RS06435 a4cb9f23b6e2e6d0b0f839ba3279c578 226 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 226 83.907 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 HVS_RS06545 27ea3d6779da2fab78f489f9a11404e3 97 SUPERFAMILY SSF103473 9 89 4.97E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain HVS_RS06545 27ea3d6779da2fab78f489f9a11404e3 97 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 14 90 1.1E-10 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 Pfam PF00920 Dehydratase family 31 549 2.1E-234 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 552 9.0E-249 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 SUPERFAMILY SSF52016 372 551 4.08E-66 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 SUPERFAMILY SSF143975 2 371 2.35E-144 T 29-03-2018 HVS_RS13000 75ce21b26fd79992490ee194dd03ba94 552 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 48.154 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 HVS_RS01010 6db118ecceb19a10e715286f47244976 286 SUPERFAMILY SSF55383 56 139 1.57E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01010 6db118ecceb19a10e715286f47244976 286 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 2.9E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01010 6db118ecceb19a10e715286f47244976 286 Gene3D G3DSA:3.30.457.10 66 127 1.6E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01010 6db118ecceb19a10e715286f47244976 286 Gene3D G3DSA:3.30.457.10 7 65 1.3E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01010 6db118ecceb19a10e715286f47244976 286 Gene3D G3DSA:3.30.457.10 128 268 3.6E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15880 a63032c1d16aa6064cc6463e96a56c46 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 66 6.4E-20 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS15880 a63032c1d16aa6064cc6463e96a56c46 73 SUPERFAMILY SSF47413 6 65 2.53E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS15880 a63032c1d16aa6064cc6463e96a56c46 73 SMART SM00530 7 61 5.7E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS15880 a63032c1d16aa6064cc6463e96a56c46 73 Gene3D G3DSA:1.10.260.40 5 73 1.3E-10 T 29-03-2018 HVS_RS13535 97b5f3da5e843bac94044ee9266a3816 262 SMART SM00650 25 190 7.7E-55 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 HVS_RS13535 97b5f3da5e843bac94044ee9266a3816 262 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HVS_RS13535 97b5f3da5e843bac94044ee9266a3816 262 Gene3D G3DSA:1.10.8.100 194 256 4.5E-23 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 HVS_RS13535 97b5f3da5e843bac94044ee9266a3816 262 SUPERFAMILY SSF53335 17 255 4.43E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13535 97b5f3da5e843bac94044ee9266a3816 262 Pfam PF00398 Ribosomal RNA adenine dimethylase 16 234 6.6E-48 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HVS_RS13535 97b5f3da5e843bac94044ee9266a3816 262 Gene3D G3DSA:3.40.50.150 3 193 1.2E-31 T 29-03-2018 HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 Gene3D G3DSA:1.10.10.10 74 151 4.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 Pfam PF04542 Sigma-70 region 2 1 61 2.3E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 Pfam PF08281 Sigma-70, region 4 82 133 5.8E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 136 4.8E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 Gene3D G3DSA:1.10.1740.10 1 73 1.8E-12 T 29-03-2018 HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 SUPERFAMILY SSF88946 2 73 2.55E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00380 10c36abcdd2ce6fa8f0dcf3af41d207f 152 SUPERFAMILY SSF88659 83 140 2.8E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS01630 a7fe66a5c83da7c2d4707ec6449538c9 154 SUPERFAMILY SSF53927 6 152 1.84E-56 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 HVS_RS01630 a7fe66a5c83da7c2d4707ec6449538c9 154 Gene3D G3DSA:3.40.140.10 1 154 1.2E-52 T 29-03-2018 HVS_RS01630 a7fe66a5c83da7c2d4707ec6449538c9 154 Pfam PF14437 MafB19-like deaminase 6 152 1.4E-45 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 HVS_RS01630 a7fe66a5c83da7c2d4707ec6449538c9 154 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 11 152 46.652 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 HVS_RS01630 a7fe66a5c83da7c2d4707ec6449538c9 154 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Pfam PF00759 Glycosyl hydrolase family 9 41 508 8.5E-116 T 29-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Gene3D G3DSA:1.50.10.10 39 516 1.3E-127 T 29-03-2018 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Gene3D G3DSA:1.10.1330.10 714 785 0.0021 T 29-03-2018 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 SUPERFAMILY SSF63446 716 784 3.04E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Pfam PF00404 Dockerin type I repeat 754 774 7.3E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Pfam PF00404 Dockerin type I repeat 720 740 1.4E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 SUPERFAMILY SSF49384 548 702 2.2E-25 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 754 773 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Pfam PF00942 Cellulose binding domain 565 633 7.8E-6 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 SUPERFAMILY SSF48208 104 517 1.07E-119 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 SUPERFAMILY SSF48208 39 77 1.07E-119 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS09380 ddcc773ffd660732fec01a02a7c32265 785 Gene3D G3DSA:2.60.40.710 543 702 1.8E-31 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS00985 2b9a20785934e6382440ef3832740627 96 Pfam PF06013 Proteins of 100 residues with WXG 4 85 1.0E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS00985 2b9a20785934e6382440ef3832740627 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 1.4E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS00985 2b9a20785934e6382440ef3832740627 96 Gene3D G3DSA:1.10.287.850 1 93 2.4E-17 T 29-03-2018 HVS_RS00985 2b9a20785934e6382440ef3832740627 96 SUPERFAMILY SSF140453 3 95 1.83E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 Gene3D G3DSA:3.20.20.70 1 313 2.4E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 SUPERFAMILY SSF102114 3 378 4.58E-114 T 29-03-2018 HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 Pfam PF13394 4Fe-4S single cluster domain 8 94 6.5E-5 T 29-03-2018 HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 Pfam PF04055 Radical SAM superfamily 9 180 9.0E-21 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 SMART SM00729 4 224 2.1E-52 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 6 357 1.1E-94 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 HVS_RS11120 52d80d2fcb67703b6ed75c009fc3f4cf 378 Pfam PF06969 HemN C-terminal domain 304 367 1.2E-15 T 29-03-2018 IPR010723 HemN, C-terminal HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 SUPERFAMILY SSF52540 307 606 2.81E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Gene3D G3DSA:3.40.50.300 1040 1230 8.4E-33 T 29-03-2018 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 SMART SM00487 254 456 2.9E-22 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 SUPERFAMILY SSF52540 1042 1477 9.47E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Pfam PF13361 UvrD-like helicase C-terminal domain 1370 1471 4.2E-15 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Pfam PF13361 UvrD-like helicase C-terminal domain 1235 1368 1.1E-7 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Pfam PF00270 DEAD/DEAH box helicase 265 438 3.1E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 SUPERFAMILY SSF53098 34 95 1.3E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Pfam PF00271 Helicase conserved C-terminal domain 478 583 3.5E-19 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 SMART SM00490 504 585 2.5E-25 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Gene3D G3DSA:3.40.50.300 238 454 1.4E-28 T 29-03-2018 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Gene3D G3DSA:3.40.50.300 1231 1490 5.0E-28 T 29-03-2018 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 249 615 2.5E-85 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Pfam PF13245 AAA domain 1053 1215 7.6E-29 T 29-03-2018 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Gene3D G3DSA:3.30.420.10 4 197 1.6E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS04170 4cdc854cc6be7ead03d14378fcf798d4 1608 Gene3D G3DSA:3.40.50.300 460 919 1.7E-37 T 29-03-2018 HVS_RS03535 9abb1a0501c6043a7dece2722b76075c 102 Pfam PF06013 Proteins of 100 residues with WXG 5 89 1.5E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03535 9abb1a0501c6043a7dece2722b76075c 102 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 90 7.0E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03535 9abb1a0501c6043a7dece2722b76075c 102 Gene3D G3DSA:1.10.287.1060 1 97 3.4E-16 T 29-03-2018 HVS_RS03535 9abb1a0501c6043a7dece2722b76075c 102 SUPERFAMILY SSF140453 5 93 9.02E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS04295 cf67959c75ed66bf70b7d36d352615e9 617 Pfam PF01609 Transposase DDE domain 355 581 1.2E-8 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HVS_RS11665 85407631891ee8dfc5b743717e0e163e 565 Pfam PF13377 Periplasmic binding protein-like domain 123 287 2.2E-18 T 29-03-2018 HVS_RS11665 85407631891ee8dfc5b743717e0e163e 565 SUPERFAMILY SSF53822 4 289 5.57E-45 T 29-03-2018 IPR028082 Periplasmic binding protein-like I HVS_RS11665 85407631891ee8dfc5b743717e0e163e 565 Gene3D G3DSA:1.10.287.130 467 556 2.3E-5 T 29-03-2018 HVS_RS11665 85407631891ee8dfc5b743717e0e163e 565 Gene3D G3DSA:3.40.50.2300 121 290 3.0E-35 T 29-03-2018 HVS_RS11665 85407631891ee8dfc5b743717e0e163e 565 Gene3D G3DSA:3.40.50.2300 1 120 2.3E-12 T 29-03-2018 HVS_RS11665 85407631891ee8dfc5b743717e0e163e 565 SUPERFAMILY SSF47384 469 509 5.3E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS03065 bd9460aa08b1fdf43a3c1138d11470e5 188 SUPERFAMILY SSF55729 2 154 1.62E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS03065 bd9460aa08b1fdf43a3c1138d11470e5 188 Pfam PF13302 Acetyltransferase (GNAT) domain 7 146 5.1E-30 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS03065 bd9460aa08b1fdf43a3c1138d11470e5 188 Gene3D G3DSA:3.40.630.30 1 180 6.4E-23 T 29-03-2018 HVS_RS05350 f0fcfb0820dd6e48128aa83ac9543625 561 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 358 557 2.6E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS05350 f0fcfb0820dd6e48128aa83ac9543625 561 Gene3D G3DSA:3.60.40.10 297 559 6.0E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS05350 f0fcfb0820dd6e48128aa83ac9543625 561 SMART SM00331 331 557 9.1E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS05350 f0fcfb0820dd6e48128aa83ac9543625 561 Pfam PF17159 Membrane-associated sensor domain 44 273 8.5E-71 T 29-03-2018 IPR033425 Membrane-associated sensor domain MASE3 HVS_RS06605 db6da04562598d8c5d25f6d28b78cbd6 65 Pfam PF01381 Helix-turn-helix 12 63 4.9E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS06605 db6da04562598d8c5d25f6d28b78cbd6 65 SUPERFAMILY SSF47413 5 64 8.59E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS06605 db6da04562598d8c5d25f6d28b78cbd6 65 Gene3D G3DSA:1.10.260.40 7 65 7.5E-9 T 29-03-2018 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 PIRSF PIRSF002161 2 180 6.0E-66 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 Gene3D G3DSA:3.30.1440.10 1 179 4.8E-78 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 Pfam PF00673 ribosomal L5P family C-terminus 85 177 1.7E-42 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 SUPERFAMILY SSF55282 4 178 7.53E-78 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.808 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15080 be4a9d273f11c6eb164c130923a3502c 180 Pfam PF00281 Ribosomal protein L5 24 80 3.3E-28 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 6.1E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 Gene3D G3DSA:3.40.50.300 28 349 6.2E-84 T 29-03-2018 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 74 9.8E-8 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 Gene3D G3DSA:1.10.1140.10 358 457 4.3E-18 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 PIRSF PIRSF039114 1 457 1.2E-236 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 457 59.064 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 SUPERFAMILY SSF47917 362 419 7.85E-6 T 29-03-2018 HVS_RS01255 55169fa79aef97f672866dfcd9673bd8 457 SUPERFAMILY SSF52540 78 354 1.01E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10480 de861256a1372fa394cca426c729a33b 277 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 16 266 4.3E-60 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 HVS_RS10480 de861256a1372fa394cca426c729a33b 277 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 15 272 16.732 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 HVS_RS10480 de861256a1372fa394cca426c729a33b 277 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 19 267 1.3E-74 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 HVS_RS16140 fda2631833c1186b816e849234dc2541 173 Gene3D G3DSA:1.10.287.950 1 173 2.5E-36 T 29-03-2018 HVS_RS16140 fda2631833c1186b816e849234dc2541 173 SMART SM00283 2 172 3.8E-5 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS16140 fda2631833c1186b816e849234dc2541 173 SUPERFAMILY SSF58104 2 172 5.93E-48 T 29-03-2018 HVS_RS16140 fda2631833c1186b816e849234dc2541 173 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 2 125 5.9E-33 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 15 287 36.379 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 Gene3D G3DSA:2.30.140.10 14 66 7.5E-14 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 Pfam PF01564 Spermine/spermidine synthase domain 71 249 5.7E-56 T 29-03-2018 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 91 104 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 SUPERFAMILY SSF53335 13 285 3.55E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 Pfam PF17284 Spermidine synthase tetramerisation domain 15 66 1.8E-11 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 Gene3D G3DSA:3.40.50.150 68 287 6.0E-34 T 29-03-2018 HVS_RS04125 6ab4ed81c32310e64a8e98543c8c8930 287 TIGRFAM TIGR00417 speE: spermidine synthase 16 280 2.5E-86 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS04465 bef6257f74f845575dc94115face31cd 178 Pfam PF01841 Transglutaminase-like superfamily 95 173 1.1E-13 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS04465 bef6257f74f845575dc94115face31cd 178 SUPERFAMILY SSF54001 105 167 9.32E-12 T 29-03-2018 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 Gene3D G3DSA:2.60.410.10 274 365 1.0E-20 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 SUPERFAMILY SSF69189 266 363 8.24E-20 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 274 364 1.3E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 SMART SM00936 274 365 2.7E-22 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 1.3E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 154 1.3E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 114 131 1.3E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 Gene3D G3DSA:3.40.710.10 20 273 1.1E-54 T 29-03-2018 HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 SUPERFAMILY SSF56601 6 274 4.95E-82 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS05080 6f85633ad34ca735b2f2985473033598 385 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 254 2.8E-76 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS00625 01f52b0e7adb249036e0f2490b4b18b0 204 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 41 179 6.0E-64 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 HVS_RS00625 01f52b0e7adb249036e0f2490b4b18b0 204 Pfam PF06866 Protein of unknown function (DUF1256) 21 177 2.1E-59 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 HVS_RS00625 01f52b0e7adb249036e0f2490b4b18b0 204 SUPERFAMILY SSF53163 10 194 1.31E-52 T 29-03-2018 IPR023430 Peptidase HybD-like domain HVS_RS00625 01f52b0e7adb249036e0f2490b4b18b0 204 Gene3D G3DSA:3.40.50.1450 8 176 2.4E-31 T 29-03-2018 IPR023430 Peptidase HybD-like domain HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 157 1.6E-51 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 Gene3D G3DSA:1.10.1040.10 179 329 1.5E-55 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 172 196 5.9E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 237 254 5.9E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 5.9E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 5.9E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 132 152 5.9E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 197 221 5.9E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 PIRSF PIRSF000114 1 331 4.3E-106 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 187 208 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 321 36.643 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 SUPERFAMILY SSF48179 178 330 4.25E-58 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 Gene3D G3DSA:3.40.50.720 1 178 1.2E-35 T 29-03-2018 HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 SUPERFAMILY SSF51735 4 177 2.55E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS10650 60cb2c98c2d62320a2ea254f53c6cc6f 332 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 179 318 9.0E-55 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 PRINTS PR01713 Nucleotide sugar epimerase signature 267 282 7.2E-31 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 PRINTS PR01713 Nucleotide sugar epimerase signature 227 242 7.2E-31 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 PRINTS PR01713 Nucleotide sugar epimerase signature 306 323 7.2E-31 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 PRINTS PR01713 Nucleotide sugar epimerase signature 40 56 7.2E-31 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 SUPERFAMILY SSF51735 12 344 5.47E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 Gene3D G3DSA:3.40.50.720 12 204 6.1E-39 T 29-03-2018 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 Gene3D G3DSA:3.90.25.10 205 346 4.9E-40 T 29-03-2018 HVS_RS13425 0560d3e0879a54a3ad2fb50cb775e6c3 346 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 273 2.1E-58 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HVS_RS14770 46a87390a9a451dc694f56b0f1100ac4 299 Pfam PF12791 Anti-sigma factor N-terminus 225 257 1.1E-4 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS14770 46a87390a9a451dc694f56b0f1100ac4 299 SUPERFAMILY SSF88946 3 70 3.06E-5 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06055 46a87390a9a451dc694f56b0f1100ac4 299 Pfam PF12791 Anti-sigma factor N-terminus 225 257 1.1E-4 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS06055 46a87390a9a451dc694f56b0f1100ac4 299 SUPERFAMILY SSF88946 3 70 3.06E-5 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS10230 4c18f0166feabd145180489c3f81a80e 487 Pfam PF02120 Flagellar hook-length control protein FliK 354 431 1.6E-18 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal HVS_RS14380 b70581988882879ab70934c429b7a26e 305 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 142 1.9E-52 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 Gene3D G3DSA:3.40.50.1370 142 304 9.6E-65 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 47 54 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 3.1E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 3.1E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 3.1E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 3.1E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 2 304 2.1E-135 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 303 7.4E-63 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 Gene3D G3DSA:3.40.50.1370 1 141 1.5E-59 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 SUPERFAMILY SSF53671 1 305 2.88E-112 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 45 59 3.9E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 118 132 3.9E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 3.9E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 78 91 3.9E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 3.9E-31 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 HVS_RS14380 b70581988882879ab70934c429b7a26e 305 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 1 305 81.013 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HVS_RS12445 b947e015d9993a7febd4fc074aae345e 199 Gene3D G3DSA:2.60.120.10 74 199 3.1E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS12445 b947e015d9993a7febd4fc074aae345e 199 Pfam PF07883 Cupin domain 99 174 7.6E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel HVS_RS12445 b947e015d9993a7febd4fc074aae345e 199 SUPERFAMILY SSF51182 58 179 7.01E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain HVS_RS09095 9acb6dd4eecdb54c9481fd83ab12d8eb 232 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 7.7E-45 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal HVS_RS09095 9acb6dd4eecdb54c9481fd83ab12d8eb 232 Gene3D G3DSA:3.40.225.10 1 231 3.4E-54 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal HVS_RS09095 9acb6dd4eecdb54c9481fd83ab12d8eb 232 SMART SM01007 7 198 2.1E-58 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal HVS_RS09095 9acb6dd4eecdb54c9481fd83ab12d8eb 232 SUPERFAMILY SSF53639 2 223 3.53E-65 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal HVS_RS00280 e59a20845b2bb3fe005f5d27c6833632 452 Pfam PF13739 Domain of unknown function (DUF4163) 42 115 1.6E-7 T 29-03-2018 IPR025303 Deacetylase PdaC HVS_RS00280 e59a20845b2bb3fe005f5d27c6833632 452 Gene3D G3DSA:3.90.640.20 143 238 6.1E-8 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 HVS_RS00280 e59a20845b2bb3fe005f5d27c6833632 452 Gene3D G3DSA:3.30.565.40 26 142 4.1E-11 T 29-03-2018 HVS_RS05690 4b7029ee3fe0f3d8c5a45585010f4307 282 SUPERFAMILY SSF55383 51 134 1.02E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05690 4b7029ee3fe0f3d8c5a45585010f4307 282 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 1.0E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05690 4b7029ee3fe0f3d8c5a45585010f4307 282 Gene3D G3DSA:3.30.457.10 61 122 3.0E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05690 4b7029ee3fe0f3d8c5a45585010f4307 282 Gene3D G3DSA:3.30.457.10 123 192 1.5E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05690 4b7029ee3fe0f3d8c5a45585010f4307 282 Gene3D G3DSA:3.30.457.10 14 60 7.1E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 353 1.6E-111 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 Gene3D G3DSA:3.40.640.10 52 246 2.9E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 Pfam PF00155 Aminotransferase class I and II 24 350 1.7E-63 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 SUPERFAMILY SSF53383 20 350 3.58E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 355 56.661 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 HVS_RS15260 7757cbb5a23cae8a470c130102f8fb32 356 Gene3D G3DSA:3.90.1150.10 247 354 7.1E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Pfam PF00809 Pterin binding enzyme 323 545 2.2E-30 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Gene3D G3DSA:3.20.20.330 2 301 9.0E-86 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 SUPERFAMILY SSF47644 594 676 1.2E-21 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Gene3D G3DSA:3.20.20.20 311 579 1.7E-49 T 29-03-2018 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 PIRSF PIRSF037472 2 805 0.0 T 29-03-2018 IPR017215 5-methyltetrahydrofolate-homocysteine S-methyltransferase, bacterial HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Gene3D G3DSA:3.40.50.280 676 804 3.9E-40 T 29-03-2018 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Pfam PF02310 B12 binding domain 687 796 2.1E-26 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 SMART SM01018 596 679 1.4E-32 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 SUPERFAMILY SSF82282 5 362 9.16E-111 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Pfam PF02607 B12 binding domain 600 671 3.5E-20 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Pfam PF02574 Homocysteine S-methyltransferase 15 286 7.1E-59 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 SUPERFAMILY SSF51717 320 576 9.16E-77 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 SUPERFAMILY SSF52242 664 802 1.44E-43 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 HVS_RS09605 68e58034760435ef3b5756bd23f68f7d 805 Gene3D G3DSA:1.10.1240.10 582 675 5.8E-24 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 SUPERFAMILY SSF54675 4 109 2.83E-30 T 29-03-2018 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 110 275 9.3E-63 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 108 1.7E-29 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 PIRSF PIRSF006250 2 277 1.6E-97 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 Gene3D G3DSA:3.20.20.70 136 266 3.0E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 Gene3D G3DSA:3.90.1170.20 1 135 5.2E-39 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 SUPERFAMILY SSF51690 110 276 2.63E-59 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 HVS_RS16005 e2e3ac26b858a8b634db3dd052850f25 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 13 276 1.4E-104 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 SUPERFAMILY SSF88659 99 173 2.49E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 Pfam PF04539 Sigma-70 region 3 105 166 2.9E-9 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 51 64 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 12 243 6.3E-105 T 29-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 213 239 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 Gene3D G3DSA:1.10.601.10 3 95 1.0E-29 T 29-03-2018 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 Pfam PF04542 Sigma-70 region 2 27 93 2.7E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 Gene3D G3DSA:1.10.1270.10 154 246 1.4E-17 T 29-03-2018 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 Pfam PF04545 Sigma-70, region 4 192 241 1.7E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 SUPERFAMILY SSF88659 161 245 1.68E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 243 6.2E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 Gene3D G3DSA:1.10.10.10 96 148 1.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 SUPERFAMILY SSF88946 7 95 1.83E-32 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 PRINTS PR00046 Major sigma-70 factor signature 51 64 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 PRINTS PR00046 Major sigma-70 factor signature 196 208 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 PRINTS PR00046 Major sigma-70 factor signature 75 83 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 PRINTS PR00046 Major sigma-70 factor signature 213 228 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 PRINTS PR00046 Major sigma-70 factor signature 228 239 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12065 88cf1dd431b696e67b7a10a1c0d77e82 246 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 21 243 1.5E-82 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS04320 16e1c11a43e51750c10de1644a48347b 497 Pfam PF00664 ABC transporter transmembrane region 166 434 1.5E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS04320 16e1c11a43e51750c10de1644a48347b 497 Gene3D G3DSA:1.20.1560.10 148 471 7.4E-59 T 29-03-2018 HVS_RS04320 16e1c11a43e51750c10de1644a48347b 497 Pfam PF03412 Peptidase C39 family 6 138 4.3E-39 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 HVS_RS04320 16e1c11a43e51750c10de1644a48347b 497 SUPERFAMILY SSF90123 153 464 4.32E-68 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS04320 16e1c11a43e51750c10de1644a48347b 497 Gene3D G3DSA:3.90.70.10 6 147 5.6E-45 T 29-03-2018 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 Gene3D G3DSA:2.30.140.10 1 54 1.2E-18 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 Pfam PF17284 Spermidine synthase tetramerisation domain 3 54 3.7E-19 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 41.983 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 Gene3D G3DSA:3.40.50.150 55 275 6.0E-44 T 29-03-2018 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 5.1E-114 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 Pfam PF01564 Spermine/spermidine synthase domain 58 236 2.6E-66 T 29-03-2018 HVS_RS08165 a9f9f011f448218c1f739ae25aefea65 275 SUPERFAMILY SSF53335 3 274 4.25E-90 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 Pfam PF12161 HsdM N-terminal domain 9 135 1.1E-27 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 Pfam PF02384 N-6 DNA Methylase 146 459 4.8E-111 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 SUPERFAMILY SSF53335 8 499 1.1E-136 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 266 272 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 263 275 2.7E-21 T 29-03-2018 HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 166 182 2.7E-21 T 29-03-2018 HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 297 321 2.7E-21 T 29-03-2018 HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 203 2.7E-21 T 29-03-2018 HVS_RS01535 4b5473483cda7311cd40ddcc1ca4526a 500 Gene3D G3DSA:3.40.50.150 164 453 1.6E-64 T 29-03-2018 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 9 269 1.5E-145 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 269 164.856 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 Gene3D G3DSA:3.60.90.10 39 197 8.7E-46 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 Pfam PF02675 S-adenosylmethionine decarboxylase 44 177 7.3E-32 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 SUPERFAMILY SSF56276 120 182 1.18E-24 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 SUPERFAMILY SSF56276 49 90 1.18E-24 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HVS_RS05120 781e982c1933da0ddeff01899b67ecd9 269 PIRSF PIRSF001356 4 269 1.4E-144 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS07865 023a13005aed406ed1177a73630350f2 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 297 5.0E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS07865 023a13005aed406ed1177a73630350f2 310 SUPERFAMILY SSF53686 3 308 3.01E-104 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS07865 023a13005aed406ed1177a73630350f2 310 Gene3D G3DSA:3.40.50.1100 44 142 3.4E-37 T 29-03-2018 HVS_RS07865 023a13005aed406ed1177a73630350f2 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HVS_RS07865 023a13005aed406ed1177a73630350f2 310 Gene3D G3DSA:3.40.50.1100 143 310 3.8E-62 T 29-03-2018 HVS_RS07865 023a13005aed406ed1177a73630350f2 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 308 5.2E-133 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HVS_RS07865 023a13005aed406ed1177a73630350f2 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 308 3.7E-139 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 Gene3D G3DSA:1.50.10.10 468 852 3.8E-48 T 29-03-2018 HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 Gene3D G3DSA:2.70.98.40 119 418 1.4E-33 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 Gene3D G3DSA:2.60.420.10 905 989 7.0E-11 T 29-03-2018 HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 Pfam PF06165 Glycosyltransferase family 36 185 403 7.1E-14 T 29-03-2018 IPR010383 Glycosyl hydrolase 94 HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 457 905 1.0E-44 T 29-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 SUPERFAMILY SSF48208 430 633 1.31E-55 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS08885 88413bcab5765e275fb210b8e24a0515 989 SUPERFAMILY SSF48208 665 987 1.31E-55 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 Gene3D G3DSA:1.10.287.130 250 302 1.4E-10 T 29-03-2018 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 Pfam PF00672 HAMP domain 193 240 6.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 288 1.5E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 Gene3D G3DSA:3.30.450.20 29 166 8.6E-4 T 29-03-2018 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 SUPERFAMILY SSF158472 193 243 2.22E-9 T 29-03-2018 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 SUPERFAMILY SSF47384 245 289 3.53E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS10680 6e5b8a0a37101eab886515b9c000d9a0 310 SMART SM00304 193 245 3.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS07760 32b182f34df1487e71eb8a8393bcffa1 256 Gene3D G3DSA:3.30.460.10 1 118 2.7E-6 T 29-03-2018 HVS_RS07760 32b182f34df1487e71eb8a8393bcffa1 256 Pfam PF10127 Predicted nucleotidyltransferase 2 248 6.3E-92 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted HVS_RS04930 452db69e7d16a93315d3efc2f615a892 379 Pfam PF00266 Aminotransferase class-V 32 326 1.6E-38 T 29-03-2018 IPR000192 Aminotransferase class V domain HVS_RS04930 452db69e7d16a93315d3efc2f615a892 379 SUPERFAMILY SSF53383 10 377 5.36E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS04930 452db69e7d16a93315d3efc2f615a892 379 PIRSF PIRSF000524 2 379 8.2E-71 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 HVS_RS04930 452db69e7d16a93315d3efc2f615a892 379 Gene3D G3DSA:3.90.1150.10 256 372 9.2E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS04930 452db69e7d16a93315d3efc2f615a892 379 Gene3D G3DSA:3.40.640.10 21 255 9.1E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS12035 86744f11280bfba3130a109886775d43 349 Gene3D G3DSA:3.40.47.10 19 242 6.4E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12035 86744f11280bfba3130a109886775d43 349 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 126 201 2.8E-7 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS12035 86744f11280bfba3130a109886775d43 349 SUPERFAMILY SSF53901 15 349 1.21E-26 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12035 86744f11280bfba3130a109886775d43 349 Gene3D G3DSA:3.40.47.10 243 348 4.1E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12035 86744f11280bfba3130a109886775d43 349 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 260 348 1.6E-19 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 SUPERFAMILY SSF53697 244 607 1.02E-108 T 29-03-2018 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 607 39.622 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Pfam PF01380 SIS domain 292 414 7.0E-29 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Pfam PF01380 SIS domain 463 589 2.1E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Gene3D G3DSA:3.40.50.10490 239 450 1.8E-67 T 29-03-2018 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Pfam PF13522 Glutamine amidotransferase domain 67 171 5.0E-17 T 29-03-2018 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 607 2.0E-242 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Gene3D G3DSA:3.60.20.10 2 238 5.0E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 Gene3D G3DSA:3.40.50.10490 451 607 2.3E-42 T 29-03-2018 HVS_RS06500 167ce9d84bec2390f2b15276c8666216 607 SUPERFAMILY SSF56235 2 233 5.23E-70 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal HVS_RS04470 8a7d576ff6d1b8d9d6654694cecad5c5 482 Pfam PF14319 Transposase zinc-binding domain 32 140 1.1E-27 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS04470 8a7d576ff6d1b8d9d6654694cecad5c5 482 Pfam PF04986 Putative transposase 167 336 2.1E-24 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS04625 8a7d576ff6d1b8d9d6654694cecad5c5 482 Pfam PF14319 Transposase zinc-binding domain 32 140 1.1E-27 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS04625 8a7d576ff6d1b8d9d6654694cecad5c5 482 Pfam PF04986 Putative transposase 167 336 2.1E-24 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 ProSitePatterns PS00902 Glutamate 5-kinase signature. 222 239 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 TIGRFAM TIGR01027 proB: glutamate 5-kinase 14 274 1.2E-92 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 Pfam PF00696 Amino acid kinase family 14 250 8.8E-43 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 276 36.925 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 Gene3D G3DSA:3.40.1160.10 3 276 1.2E-60 T 29-03-2018 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 PIRSF PIRSF000729 10 276 3.9E-95 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 SUPERFAMILY SSF53633 14 272 7.85E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 PRINTS PR00474 Glutamate 5-kinase family signature 163 190 1.9E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 1.9E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 1.9E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 1.9E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HVS_RS03215 d69bee491840ddf8c1a6a227440d2942 276 PRINTS PR00474 Glutamate 5-kinase family signature 224 244 1.9E-52 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 HVS_RS06965 0ede90991d4f03a5472c08082e0e2922 429 Pfam PF02371 Transposase IS116/IS110/IS902 family 284 376 8.7E-27 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HVS_RS06965 0ede90991d4f03a5472c08082e0e2922 429 Pfam PF01548 Transposase 7 163 3.7E-34 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 313 39.189 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 PIRSF PIRSF004486 1 313 3.7E-112 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 SUPERFAMILY SSF81799 116 217 3.14E-35 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 Gene3D G3DSA:1.10.150.170 114 219 8.5E-40 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 312 1.4E-116 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 Pfam PF01795 MraW methylase family 2 313 1.3E-120 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 SUPERFAMILY SSF53335 4 115 1.96E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS10465 354bd60219bf3fa081130c27c5b2d8ae 313 SUPERFAMILY SSF53335 217 313 1.96E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13260 13ff90327ce4bc83d7b24fa80c94834a 119 Gene3D G3DSA:3.40.1800.10 33 119 1.5E-14 T 29-03-2018 HVS_RS13260 13ff90327ce4bc83d7b24fa80c94834a 119 Pfam PF01844 HNH endonuclease 65 110 5.8E-15 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 HVS_RS13260 13ff90327ce4bc83d7b24fa80c94834a 119 SMART SM00507 53 106 9.2E-11 T 29-03-2018 IPR003615 HNH nuclease HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 4 267 9.6E-101 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 Gene3D G3DSA:1.10.10.10 155 265 3.6E-46 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 159 262 4.0E-41 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 Pfam PF00072 Response regulator receiver domain 7 121 3.5E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 SUPERFAMILY SSF52172 4 130 9.82E-32 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 Gene3D G3DSA:3.40.50.2300 4 140 9.3E-29 T 29-03-2018 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 PIRSF PIRSF002937 1 269 4.7E-107 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 SMART SM00448 5 120 5.3E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 159 249 2.0E-40 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 HVS_RS11945 def255baab16eb492d42eebb6d483d9e 269 SUPERFAMILY SSF46894 152 267 7.23E-42 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS07240 16d2681047cc2a8f947c091b6c171172 484 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 476 77.471 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HVS_RS07240 16d2681047cc2a8f947c091b6c171172 484 SUPERFAMILY SSF75304 2 480 3.01E-142 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HVS_RS07240 16d2681047cc2a8f947c091b6c171172 484 Pfam PF01425 Amidase 24 465 2.1E-134 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HVS_RS07240 16d2681047cc2a8f947c091b6c171172 484 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 475 1.6E-170 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HVS_RS07240 16d2681047cc2a8f947c091b6c171172 484 Gene3D G3DSA:3.90.1300.10 1 484 1.4E-151 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HVS_RS04405 a93a935985de644a20249aac7fb857c8 436 Pfam PF16254 Domain of unknown function (DUF4910) 16 354 3.5E-109 T 29-03-2018 IPR032589 Domain of unknown function DUF4910 HVS_RS04405 a93a935985de644a20249aac7fb857c8 436 SUPERFAMILY SSF53187 90 354 2.35E-43 T 29-03-2018 HVS_RS04405 a93a935985de644a20249aac7fb857c8 436 Gene3D G3DSA:3.40.630.10 1 354 1.4E-16 T 29-03-2018 HVS_RS04405 a93a935985de644a20249aac7fb857c8 436 Pfam PF09940 Domain of unknown function (DUF2172) 66 157 6.8E-42 T 29-03-2018 IPR032610 Domain of unknown function DUF2172 HVS_RS04405 a93a935985de644a20249aac7fb857c8 436 PIRSF PIRSF015244 1 431 1.3E-176 T 29-03-2018 IPR012353 Uncharacterised conserved protein UCP01524, polysaccharide biosynthesis aminopeptidase-like HVS_RS04405 a93a935985de644a20249aac7fb857c8 436 Pfam PF16221 winged helix-turn-helix 357 429 4.8E-24 T 29-03-2018 IPR032622 UCP01524, winged helix-turn-helix domain HVS_RS05705 c453ac3069aef49236731eff813e0e26 282 SUPERFAMILY SSF55383 51 134 1.96E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05705 c453ac3069aef49236731eff813e0e26 282 Gene3D G3DSA:3.30.457.10 61 122 3.4E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05705 c453ac3069aef49236731eff813e0e26 282 Gene3D G3DSA:3.30.457.10 14 60 7.1E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05705 c453ac3069aef49236731eff813e0e26 282 Gene3D G3DSA:3.30.457.10 123 247 2.7E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05705 c453ac3069aef49236731eff813e0e26 282 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 9.0E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08680 8dbd339770ab8119c669eac491a9e08a 340 SUPERFAMILY SSF52540 69 300 3.12E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08680 8dbd339770ab8119c669eac491a9e08a 340 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 45 325 4.2E-110 T 29-03-2018 IPR014217 Sporulation stage III, protein AA HVS_RS08680 8dbd339770ab8119c669eac491a9e08a 340 Gene3D G3DSA:3.40.50.300 69 315 6.9E-11 T 29-03-2018 HVS_RS08680 8dbd339770ab8119c669eac491a9e08a 340 SMART SM00382 166 314 0.0023 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 PRINTS PR00094 Adenylate kinase signature 160 175 1.5E-37 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 PRINTS PR00094 Adenylate kinase signature 81 97 1.5E-37 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 PRINTS PR00094 Adenylate kinase signature 4 17 1.5E-37 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 PRINTS PR00094 Adenylate kinase signature 177 191 1.5E-37 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 PRINTS PR00094 Adenylate kinase signature 32 46 1.5E-37 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 Pfam PF05191 Adenylate kinase, active site lid 127 162 3.3E-14 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 Gene3D G3DSA:3.40.50.300 1 215 5.5E-69 T 29-03-2018 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 Pfam PF00406 Adenylate kinase 5 190 1.0E-62 T 29-03-2018 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 SUPERFAMILY SSF52540 1 212 4.32E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 Hamap MF_00235 Adenylate kinase [adk]. 1 213 51.73 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 HVS_RS15035 7c789faa933d12d5cfa3c3b3e6b04de1 215 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 9.3E-85 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 HVS_RS04375 c37bc145f60cf0a005ecda20d521f862 165 Gene3D G3DSA:3.40.50.720 3 165 6.7E-17 T 29-03-2018 HVS_RS04375 c37bc145f60cf0a005ecda20d521f862 165 Pfam PF02719 Polysaccharide biosynthesis protein 8 119 1.6E-32 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain HVS_RS04190 d2fb7e52b63481dda6eec61b5e8114d3 563 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 9 441 9.2E-151 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 HVS_RS04190 d2fb7e52b63481dda6eec61b5e8114d3 563 Gene3D G3DSA:3.30.200.20 103 245 4.1E-27 T 29-03-2018 HVS_RS04190 d2fb7e52b63481dda6eec61b5e8114d3 563 SUPERFAMILY SSF56112 96 159 3.47E-28 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS04190 d2fb7e52b63481dda6eec61b5e8114d3 563 SUPERFAMILY SSF56112 203 312 3.47E-28 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS04190 d2fb7e52b63481dda6eec61b5e8114d3 563 Pfam PF03109 ABC1 family 113 231 4.4E-37 T 29-03-2018 IPR004147 UbiB domain HVS_RS12055 8bd2848f542e016c1923941b2c6bd43c 162 Pfam PF00588 SpoU rRNA Methylase family 2 140 2.6E-37 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HVS_RS12055 8bd2848f542e016c1923941b2c6bd43c 162 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 151 1.3E-61 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HVS_RS12055 8bd2848f542e016c1923941b2c6bd43c 162 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 1 149 34.652 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HVS_RS12055 8bd2848f542e016c1923941b2c6bd43c 162 PIRSF PIRSF029256 1 152 2.3E-65 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HVS_RS12055 8bd2848f542e016c1923941b2c6bd43c 162 SUPERFAMILY SSF75217 2 151 9.16E-44 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS12055 8bd2848f542e016c1923941b2c6bd43c 162 Gene3D G3DSA:3.40.1280.10 1 160 1.7E-42 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS10060 2f0a973a290c9260671267573da230ed 635 Pfam PF12791 Anti-sigma factor N-terminus 8 59 2.1E-8 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS10060 2f0a973a290c9260671267573da230ed 635 SUPERFAMILY SSF49384 485 635 9.42E-44 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS10060 2f0a973a290c9260671267573da230ed 635 Gene3D G3DSA:2.60.40.710 484 635 8.4E-46 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS10060 2f0a973a290c9260671267573da230ed 635 SMART SM01067 490 572 1.5E-20 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS10060 2f0a973a290c9260671267573da230ed 635 Pfam PF00942 Cellulose binding domain 490 571 9.1E-19 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS05425 08d53b966f77b4bd93c6c6a308a797cd 290 SUPERFAMILY SSF51730 1 288 1.0E-88 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like HVS_RS05425 08d53b966f77b4bd93c6c6a308a797cd 290 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 14 285 2.6E-95 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 HVS_RS05425 08d53b966f77b4bd93c6c6a308a797cd 290 Pfam PF02219 Methylenetetrahydrofolate reductase 6 285 2.1E-84 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 HVS_RS05425 08d53b966f77b4bd93c6c6a308a797cd 290 Gene3D G3DSA:3.20.20.220 1 290 2.6E-95 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 SUPERFAMILY SSF48179 162 269 2.38E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 Gene3D G3DSA:1.10.3730.10 165 270 8.6E-45 T 29-03-2018 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 SUPERFAMILY SSF51735 4 161 1.09E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 223 245 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 1.8E-17 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 267 1.3E-87 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 266 3.2E-40 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 Gene3D G3DSA:3.40.50.720 2 164 9.9E-28 T 29-03-2018 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 267 26.938 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 HVS_RS09535 53024a4639eb3dbce1909a6a0cb1f3b5 270 PIRSF PIRSF000193 3 270 2.2E-86 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 Gene3D G3DSA:3.30.70.1560 148 216 1.1E-22 T 29-03-2018 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 Gene3D G3DSA:3.10.290.10 2 60 1.2E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 Pfam PF00849 RNA pseudouridylate synthase 66 199 1.6E-20 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 SUPERFAMILY SSF55174 5 97 2.8E-16 T 29-03-2018 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 Gene3D G3DSA:3.30.70.580 61 147 1.3E-17 T 29-03-2018 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 SUPERFAMILY SSF55120 66 234 3.52E-43 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 Pfam PF01479 S4 domain 5 46 1.3E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 SMART SM00363 5 63 5.2E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS12145 83a1b2ca0339008fad87e6d596b3aff3 246 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 230 7.2E-45 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 Gene3D G3DSA:3.30.1490.20 7 170 8.2E-35 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 SUPERFAMILY SSF56059 8 281 4.12E-64 T 29-03-2018 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 Gene3D G3DSA:3.50.30.10 752 856 6.0E-34 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 Pfam PF00391 PEP-utilising enzyme, mobile domain 779 850 2.9E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 Gene3D G3DSA:3.30.470.20 171 277 3.8E-26 T 29-03-2018 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 SUPERFAMILY SSF52009 749 854 1.01E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 229 278 4.9E-6 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HVS_RS00345 5b7282c3198139657a6b860802c87297 857 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 13 217 2.1E-51 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 HVS_RS11920 bdcec868456645dabaeea052e5c471a9 69 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 4 61 1.7E-27 T 29-03-2018 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide HVS_RS11920 bdcec868456645dabaeea052e5c471a9 69 Pfam PF08984 Domain of unknown function (DUF1858) 4 57 7.9E-21 T 29-03-2018 IPR015077 Domain of unknown function DUF1858 HVS_RS11920 bdcec868456645dabaeea052e5c471a9 69 SUPERFAMILY SSF140683 1 66 4.32E-17 T 29-03-2018 HVS_RS11920 bdcec868456645dabaeea052e5c471a9 69 Gene3D G3DSA:1.10.3910.10 1 67 8.6E-25 T 29-03-2018 HVS_RS00290 aae1402465237ae1fa6aba1aac76e66b 139 Gene3D G3DSA:2.40.160.20 1 138 1.3E-20 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 HVS_RS00290 aae1402465237ae1fa6aba1aac76e66b 139 Pfam PF11578 Protein of unknown function (DUF3237) 4 137 1.5E-11 T 29-03-2018 IPR020915 Uncharacterised protein family UPF0311 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 SUPERFAMILY SSF101898 251 443 1.78E-8 T 29-03-2018 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 108 144 2.2E-10 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 171 207 9.2E-10 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 318 354 7.1E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 384 417 4.4E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 535 564 1.3E-4 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 66 103 3.7E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 150 186 1.4E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 234 270 6.2E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 421 458 3.1E-9 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 571 601 3.0E-5 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 192 228 6.0E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF05593 RHS Repeat 276 311 1.9E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1025 1049 0.0019 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Gene3D G3DSA:2.130.10.10 243 461 3.4E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 255 296 1.2E-11 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 150 191 2.4E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 380 420 1.1E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 571 606 0.0016 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 171 208 8.0E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 297 334 0.0024 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 421 462 8.0E-8 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 213 253 1.1E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 66 103 8.9E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 339 379 0.0011 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 108 143 2.2E-10 T 29-03-2018 IPR006530 YD repeat HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Gene3D G3DSA:2.120.10.30 56 242 0.079 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 SMART SM00306 912 1006 1.5E-13 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Pfam PF07591 Pretoxin HINT domain 920 1049 2.7E-29 T 29-03-2018 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 SUPERFAMILY SSF51294 914 1047 1.22E-25 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 702 782 1.7E-17 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS03890 024a9a748d62e498e25912cad5387549 1160 Gene3D G3DSA:2.170.16.10 901 1048 5.9E-38 T 29-03-2018 HVS_RS05805 8d8d82ee0ca5e8298d8d52de1aa2457f 345 Gene3D G3DSA:3.40.50.1820 46 278 9.8E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS05805 8d8d82ee0ca5e8298d8d52de1aa2457f 345 SUPERFAMILY SSF53474 134 277 1.01E-6 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS05805 8d8d82ee0ca5e8298d8d52de1aa2457f 345 Pfam PF11187 Protein of unknown function (DUF2974) 113 270 3.5E-20 T 29-03-2018 IPR024499 Protein of unknown function DUF2974 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 361 177.197 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 Gene3D G3DSA:3.20.20.150 1 361 8.7E-108 T 29-03-2018 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 358 8.3E-122 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 354 4.2E-162 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 PIRSF PIRSF016049 154 359 3.5E-81 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 PIRSF PIRSF016049 1 170 8.4E-48 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 HVS_RS02260 96abd15c50ece775f86dff1dfc48a7cd 361 SUPERFAMILY SSF51658 1 352 2.64E-96 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS10795 7e0330a133a935e6d61d691b20545578 227 SMART SM00382 32 218 2.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS10795 7e0330a133a935e6d61d691b20545578 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS10795 7e0330a133a935e6d61d691b20545578 227 Gene3D G3DSA:3.40.50.300 1 224 1.7E-64 T 29-03-2018 HVS_RS10795 7e0330a133a935e6d61d691b20545578 227 Pfam PF00005 ABC transporter 23 169 2.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS10795 7e0330a133a935e6d61d691b20545578 227 SUPERFAMILY SSF52540 3 222 5.32E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 SUPERFAMILY SSF143800 1 65 3.61E-27 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 PRINTS PR01249 Ribosomal protein L31 signature 45 63 2.2E-24 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.2E-24 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 PRINTS PR01249 Ribosomal protein L31 signature 30 45 2.2E-24 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 Pfam PF01197 Ribosomal protein L31 1 64 5.1E-33 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 29.863 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS01240 1696d46db3b5c3a4d5ceecb927dfa224 69 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 7.7E-32 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS13400 ebd7c6395d0a57391ef3edffcccbda29 374 Pfam PF04230 Polysaccharide pyruvyl transferase 14 306 2.3E-38 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 SUPERFAMILY SSF55073 140 296 5.34E-42 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 131 294 1.6E-45 T 29-03-2018 IPR000160 GGDEF domain HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 SMART SM00471 327 462 6.0E-17 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 TIGRFAM TIGR00277 HDIG: HDIG domain 331 421 1.6E-7 T 29-03-2018 IPR006675 HDIG domain HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 Gene3D G3DSA:3.30.70.270 118 283 7.1E-46 T 29-03-2018 HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 SUPERFAMILY SSF109604 320 491 3.14E-40 T 29-03-2018 HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 SMART SM00267 124 295 1.8E-47 T 29-03-2018 IPR000160 GGDEF domain HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 Pfam PF00990 Diguanylate cyclase, GGDEF domain 135 291 5.3E-42 T 29-03-2018 IPR000160 GGDEF domain HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 Pfam PF01966 HD domain 331 453 3.2E-20 T 29-03-2018 IPR006674 HD domain HVS_RS08025 dbb8803b53ed3e553d8173f8be9932b9 497 Gene3D G3DSA:1.10.3210.10 284 494 1.5E-49 T 29-03-2018 HVS_RS00600 aca8a0e95453f4684e34ffd6e9696817 425 SUPERFAMILY SSF50182 185 251 4.25E-12 T 29-03-2018 IPR010920 LSM domain HVS_RS00600 aca8a0e95453f4684e34ffd6e9696817 425 Gene3D G3DSA:2.30.30.60 201 251 9.1E-11 T 29-03-2018 HVS_RS00600 aca8a0e95453f4684e34ffd6e9696817 425 Pfam PF00924 Mechanosensitive ion channel 142 396 3.4E-51 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HVS_RS07010 99af6c48656d168d5960131c62c0e6d9 132 Pfam PF07009 NusG domain II 13 117 1.6E-27 T 29-03-2018 IPR024045 NusG, domain 2 HVS_RS07010 99af6c48656d168d5960131c62c0e6d9 132 Gene3D G3DSA:2.60.320.10 21 132 2.5E-24 T 29-03-2018 HVS_RS01265 3709568c7833c8ef391bd809f3c1c56c 106 SUPERFAMILY SSF159468 4 102 3.01E-26 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01265 3709568c7833c8ef391bd809f3c1c56c 106 Pfam PF01990 ATP synthase (F/14-kDa) subunit 4 93 5.2E-27 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01265 3709568c7833c8ef391bd809f3c1c56c 106 Gene3D G3DSA:3.40.50.10580 1 106 1.2E-30 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01470 0ea6a796b26ca2e7e3bc5ebfde083728 229 Gene3D G3DSA:3.90.550.10 1 208 9.9E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01470 0ea6a796b26ca2e7e3bc5ebfde083728 229 SUPERFAMILY SSF53448 2 203 9.55E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01470 0ea6a796b26ca2e7e3bc5ebfde083728 229 Pfam PF02348 Cytidylyltransferase 5 203 8.6E-35 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 HVS_RS02640 41530094862deb1ab3d87200e17fb680 279 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS02640 41530094862deb1ab3d87200e17fb680 279 SUPERFAMILY SSF52540 3 227 6.3E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02640 41530094862deb1ab3d87200e17fb680 279 Pfam PF00005 ABC transporter 22 161 1.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS02640 41530094862deb1ab3d87200e17fb680 279 Gene3D G3DSA:3.40.50.300 1 260 2.6E-62 T 29-03-2018 HVS_RS02640 41530094862deb1ab3d87200e17fb680 279 SMART SM00382 31 211 8.8E-22 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS03360 13fdc88e147e1bdc982492a78ae5d38e 496 Pfam PF02952 L-fucose isomerase, C-terminal domain 353 478 9.8E-32 T 29-03-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 HVS_RS03360 13fdc88e147e1bdc982492a78ae5d38e 496 SUPERFAMILY SSF53743 1 319 8.63E-59 T 29-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 HVS_RS13525 19ee26a5a59e83e7d29ef167cc57395d 822 Gene3D G3DSA:3.20.20.80 7 822 4.1E-60 T 29-03-2018 HVS_RS13525 19ee26a5a59e83e7d29ef167cc57395d 822 Pfam PF00704 Glycosyl hydrolases family 18 58 290 5.4E-13 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HVS_RS13525 19ee26a5a59e83e7d29ef167cc57395d 822 SUPERFAMILY SSF51445 782 815 9.46E-22 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS13525 19ee26a5a59e83e7d29ef167cc57395d 822 SUPERFAMILY SSF51445 21 228 9.46E-22 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS00710 9fac975e3a7b956119f606ce273f0389 133 Gene3D G3DSA:3.40.50.2300 1 133 3.3E-37 T 29-03-2018 HVS_RS00710 9fac975e3a7b956119f606ce273f0389 133 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 124 3.6E-21 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS00710 9fac975e3a7b956119f606ce273f0389 133 SMART SM00226 3 127 4.0E-37 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS00710 9fac975e3a7b956119f606ce273f0389 133 SUPERFAMILY SSF52788 1 126 5.1E-37 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 Gene3D G3DSA:3.30.1330.30 1 70 1.5E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 SUPERFAMILY SSF55315 2 69 5.39E-20 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 PRINTS PR00884 Ribosomal protein HS6 signature 44 54 4.8E-6 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 PRINTS PR00884 Ribosomal protein HS6 signature 18 29 4.8E-6 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 PRINTS PR00884 Ribosomal protein HS6 signature 8 18 4.8E-6 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 PRINTS PR00884 Ribosomal protein HS6 signature 58 70 4.8E-6 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12945 541e9840e0d6faa2ee83a2d65596d5fd 70 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 2 68 1.6E-15 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 Gene3D G3DSA:2.160.20.10 191 429 2.3E-59 T 29-03-2018 IPR012334 Pectin lyase fold HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 SUPERFAMILY SSF63446 29 95 1.57E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 SUPERFAMILY SSF51126 142 427 4.4E-69 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 Gene3D G3DSA:2.160.20.10 138 190 9.9E-12 T 29-03-2018 IPR012334 Pectin lyase fold HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 SMART SM00656 153 367 7.0E-41 T 29-03-2018 IPR002022 Pectate lyase HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 66 85 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS04855 54cd21d8ce4bafb75d149db44cb9c1e3 429 Pfam PF00544 Pectate lyase 189 361 9.4E-32 T 29-03-2018 IPR002022 Pectate lyase HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SMART SM00740 592 656 7.6E-10 T 29-03-2018 IPR005543 PASTA domain HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SMART SM00740 659 718 2.8E-5 T 29-03-2018 IPR005543 PASTA domain HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 Gene3D G3DSA:3.90.1310.10 25 226 9.1E-48 T 29-03-2018 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SUPERFAMILY SSF56601 176 276 7.27E-106 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SUPERFAMILY SSF56601 306 585 7.27E-106 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 Gene3D G3DSA:3.40.710.10 227 598 8.8E-103 T 29-03-2018 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SUPERFAMILY SSF56519 54 225 4.19E-44 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SUPERFAMILY SSF54184 660 713 1.44E-8 T 29-03-2018 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 SUPERFAMILY SSF54184 596 654 3.14E-7 T 29-03-2018 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 Pfam PF00905 Penicillin binding protein transpeptidase domain 252 572 8.9E-78 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 Pfam PF03717 Penicillin-binding Protein dimerisation domain 55 206 9.4E-25 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 Pfam PF03793 PASTA domain 663 713 2.7E-10 T 29-03-2018 IPR005543 PASTA domain HVS_RS10455 2577b1442b02d67dcc148a66176b328e 722 Pfam PF03793 PASTA domain 596 656 4.4E-9 T 29-03-2018 IPR005543 PASTA domain HVS_RS05915 103c4044ec018e4a2bb08163081c0ab5 452 Pfam PF06245 Protein of unknown function (DUF1015) 19 448 1.8E-90 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 HVS_RS09085 1d99fc257094cac42b86bcc7570f6ed5 500 Gene3D G3DSA:2.60.40.1180 372 500 1.3E-34 T 29-03-2018 HVS_RS09085 1d99fc257094cac42b86bcc7570f6ed5 500 SUPERFAMILY SSF51445 17 379 2.01E-113 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS09085 1d99fc257094cac42b86bcc7570f6ed5 500 Gene3D G3DSA:3.20.20.80 18 371 6.2E-114 T 29-03-2018 HVS_RS09085 1d99fc257094cac42b86bcc7570f6ed5 500 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 491 4.0E-42 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 HVS_RS09085 1d99fc257094cac42b86bcc7570f6ed5 500 SMART SM00813 291 491 1.8E-72 T 29-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 HVS_RS09085 1d99fc257094cac42b86bcc7570f6ed5 500 SUPERFAMILY SSF51011 368 498 1.58E-37 T 29-03-2018 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 SUPERFAMILY SSF51905 2 291 6.41E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 SUPERFAMILY SSF51905 385 428 6.41E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 Gene3D G3DSA:3.50.50.60 1 226 3.3E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 Pfam PF01593 Flavin containing amine oxidoreductase 11 425 6.3E-33 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 Gene3D G3DSA:3.90.660.10 227 387 9.8E-10 T 29-03-2018 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.5E-7 T 29-03-2018 HVS_RS03280 2cd0eb8eddd6962fa37a42627a138779 429 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.5E-7 T 29-03-2018 HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 294 421 3.8E-35 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 SUPERFAMILY SSF52540 83 218 9.29E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 SUPERFAMILY SSF52540 260 503 1.1E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 Gene3D G3DSA:3.40.50.300 255 431 6.0E-43 T 29-03-2018 HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 Gene3D G3DSA:1.10.8.60 432 517 7.7E-13 T 29-03-2018 HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 Gene3D G3DSA:1.10.8.60 189 251 0.042 T 29-03-2018 HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 Gene3D G3DSA:3.40.50.300 67 188 0.18 T 29-03-2018 HVS_RS00195 d9ba3814cc7b9f1443b0c1e147c7af73 534 SMART SM00382 290 426 4.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS06145 f6807496e6f4c1c5aa30ae9adcf5570c 367 Gene3D G3DSA:3.40.50.2000 2 202 8.9E-77 T 29-03-2018 HVS_RS06145 f6807496e6f4c1c5aa30ae9adcf5570c 367 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 361 3.5E-119 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 HVS_RS06145 f6807496e6f4c1c5aa30ae9adcf5570c 367 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 361 2.2E-156 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 HVS_RS06145 f6807496e6f4c1c5aa30ae9adcf5570c 367 SUPERFAMILY SSF53756 1 363 2.67E-137 T 29-03-2018 HVS_RS06145 f6807496e6f4c1c5aa30ae9adcf5570c 367 Gene3D G3DSA:3.40.50.2000 203 348 9.6E-37 T 29-03-2018 HVS_RS10280 d633e532830fa4e7915f77726accc3de 439 Gene3D G3DSA:3.50.50.60 5 370 1.4E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS10280 d633e532830fa4e7915f77726accc3de 439 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 432 6.1E-206 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HVS_RS10280 d633e532830fa4e7915f77726accc3de 439 SUPERFAMILY SSF51905 7 365 6.02E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS10280 d633e532830fa4e7915f77726accc3de 439 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 5 434 36.564 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HVS_RS10280 d633e532830fa4e7915f77726accc3de 439 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 HVS_RS10280 d633e532830fa4e7915f77726accc3de 439 Pfam PF01134 Glucose inhibited division protein A 5 367 7.2E-117 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 HVS_RS10885 bbc47419dee3b30bb8c39c8750e6e20f 62 SUPERFAMILY SSF143800 1 61 1.96E-20 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10885 bbc47419dee3b30bb8c39c8750e6e20f 62 Gene3D G3DSA:2.30.170.40 2 61 6.5E-18 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10885 bbc47419dee3b30bb8c39c8750e6e20f 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 15.942 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS10885 bbc47419dee3b30bb8c39c8750e6e20f 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 55 2.0E-20 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS10885 bbc47419dee3b30bb8c39c8750e6e20f 62 Pfam PF00830 Ribosomal L28 family 3 56 8.4E-20 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11860 a8c99f2236b8d0af2526e3bdcbf148b2 327 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 10 326 6.8E-26 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 198 2.0E-82 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 Gene3D G3DSA:3.90.870.10 1 211 2.6E-98 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 2 395 56.057 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 SUPERFAMILY SSF55821 3 201 2.75E-88 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 203 399 43.205 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 PIRSF PIRSF001259 1 406 8.0E-188 T 29-03-2018 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 207 397 7.7E-85 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 SUPERFAMILY SSF142695 203 376 2.22E-73 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 Pfam PF00925 GTP cyclohydrolase II 208 373 2.2E-76 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 202 40.765 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS05445 5f274cf41760b12108dcbb44c4a1e5c8 412 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 197 1.8E-89 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 SUPERFAMILY SSF54909 60 143 5.36E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 43 2.9E-6 T 29-03-2018 HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 Gene3D G3DSA:1.10.10.10 2 48 9.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 SMART SM00344 2 107 9.7E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 Gene3D G3DSA:3.30.70.920 49 146 7.0E-26 T 29-03-2018 HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 SUPERFAMILY SSF46785 3 54 7.33E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11255 d4d9394d0a4e00dfd62e21d4fbc88fb1 159 Pfam PF01037 Lrp/AsnC ligand binding domain 64 137 5.9E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain HVS_RS11565 ab100218c77e0df0bdf42e8569df512a 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.76 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11565 ab100218c77e0df0bdf42e8569df512a 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS11565 ab100218c77e0df0bdf42e8569df512a 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 4.5E-39 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11565 ab100218c77e0df0bdf42e8569df512a 103 SUPERFAMILY SSF141091 1 102 4.45E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11565 ab100218c77e0df0bdf42e8569df512a 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 9.3E-42 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12515 5aff9c64396a41992d6bb51b8762e97e 221 Pfam PF00665 Integrase core domain 129 208 5.0E-8 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS12515 5aff9c64396a41992d6bb51b8762e97e 221 Gene3D G3DSA:3.30.420.10 121 208 7.7E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS12515 5aff9c64396a41992d6bb51b8762e97e 221 Gene3D G3DSA:1.10.10.60 2 44 5.0E-9 T 29-03-2018 HVS_RS12515 5aff9c64396a41992d6bb51b8762e97e 221 SUPERFAMILY SSF88659 3 42 2.62E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Pfam PF12848 ABC transporter 231 317 1.8E-23 T 29-03-2018 IPR032781 ABC-transporter extension domain HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 SMART SM00382 354 520 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 SMART SM00382 28 237 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Gene3D G3DSA:3.40.50.300 291 557 1.3E-57 T 29-03-2018 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Gene3D G3DSA:3.40.50.300 2 273 3.1E-59 T 29-03-2018 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Gene3D G3DSA:1.20.58.410 559 641 3.1E-5 T 29-03-2018 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 SUPERFAMILY SSF52540 5 246 2.28E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Pfam PF00005 ABC transporter 19 192 3.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Pfam PF00005 ABC transporter 346 475 5.2E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 Pfam PF16326 ABC transporter C-terminal domain 567 633 5.3E-10 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 SUPERFAMILY SSF52540 313 522 8.04E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12685 c4fb5e9b18385af31e537987b0218c8a 644 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS14705 23651c91109b346889350f4495f8944f 598 Gene3D G3DSA:3.20.20.80 270 598 2.5E-73 T 29-03-2018 HVS_RS14705 23651c91109b346889350f4495f8944f 598 SUPERFAMILY SSF49785 129 253 2.38E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS14705 23651c91109b346889350f4495f8944f 598 Pfam PF03422 Carbohydrate binding module (family 6) 135 253 1.1E-28 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS14705 23651c91109b346889350f4495f8944f 598 SMART SM00606 127 254 5.7E-38 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS14705 23651c91109b346889350f4495f8944f 598 Pfam PF00404 Dockerin type I repeat 42 62 2.4E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS14705 23651c91109b346889350f4495f8944f 598 Gene3D G3DSA:2.60.120.260 124 257 4.6E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS14705 23651c91109b346889350f4495f8944f 598 Pfam PF00331 Glycosyl hydrolase family 10 277 593 1.7E-114 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS14705 23651c91109b346889350f4495f8944f 598 ProSitePatterns PS00018 EF-hand calcium-binding domain. 42 54 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS14705 23651c91109b346889350f4495f8944f 598 SMART SM00633 321 595 1.4E-129 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS14705 23651c91109b346889350f4495f8944f 598 Gene3D G3DSA:1.10.1330.10 35 107 3.8E-5 T 29-03-2018 HVS_RS14705 23651c91109b346889350f4495f8944f 598 SUPERFAMILY SSF51445 271 597 2.9E-111 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS14705 23651c91109b346889350f4495f8944f 598 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 76 95 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS14705 23651c91109b346889350f4495f8944f 598 SUPERFAMILY SSF63446 38 106 2.06E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS14705 23651c91109b346889350f4495f8944f 598 PRINTS PR00134 Glycosyl hydrolase family 10 signature 396 407 7.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS14705 23651c91109b346889350f4495f8944f 598 PRINTS PR00134 Glycosyl hydrolase family 10 signature 443 454 7.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS14705 23651c91109b346889350f4495f8944f 598 PRINTS PR00134 Glycosyl hydrolase family 10 signature 352 364 7.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS14705 23651c91109b346889350f4495f8944f 598 PRINTS PR00134 Glycosyl hydrolase family 10 signature 473 485 7.7E-18 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 Pfam PF12327 FtsZ family, C-terminal domain 222 316 8.8E-39 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 355 39.631 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 327 2.5E-137 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 Gene3D G3DSA:3.30.1330.20 216 322 5.1E-48 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 PRINTS PR00423 Cell division protein FtsZ signature 189 211 2.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 PRINTS PR00423 Cell division protein FtsZ signature 126 147 2.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 PRINTS PR00423 Cell division protein FtsZ signature 212 233 2.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 PRINTS PR00423 Cell division protein FtsZ signature 98 118 2.5E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 Gene3D G3DSA:3.40.50.1440 12 215 3.6E-44 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 SUPERFAMILY SSF52490 12 208 1.57E-72 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 4.5E-43 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 SMART SM00864 13 205 9.6E-117 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 SUPERFAMILY SSF55307 204 319 8.7E-46 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 HVS_RS10330 2b9ba54cc4e37157cc08ae2fb4d52a36 366 SMART SM00865 207 324 9.4E-59 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 Gene3D G3DSA:3.20.20.70 1 309 5.9E-117 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 308 2.1E-105 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 PIRSF PIRSF001359 1 309 7.9E-105 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 308 2.8E-93 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 SUPERFAMILY SSF51569 3 309 8.06E-112 T 29-03-2018 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 309 1.1E-114 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 HVS_RS12355 44a0e6288fc47af1c430cba5a180a107 309 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HVS_RS09650 c8b6786d4682b9f103525eb0bf5e0249 430 SUPERFAMILY SSF53383 45 373 1.42E-44 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS09650 c8b6786d4682b9f103525eb0bf5e0249 430 Gene3D G3DSA:3.40.640.10 66 279 6.8E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS09650 c8b6786d4682b9f103525eb0bf5e0249 430 Pfam PF06838 Methionine gamma-lyase 22 422 9.2E-195 T 29-03-2018 IPR009651 Putative methionine gamma-lyase HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 SUPERFAMILY SSF57863 81 235 4.45E-30 T 29-03-2018 HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 SUPERFAMILY SSF50249 1 79 8.74E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 Pfam PF11967 Recombination protein O N terminal 1 79 3.1E-23 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 244 4.5E-49 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 Pfam PF02565 Recombination protein O C terminal 84 239 2.3E-27 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 Hamap MF_00201 DNA repair protein RecO [recO]. 2 246 25.217 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HVS_RS07435 452639278c0a887471c84c5c52c42d48 253 Gene3D G3DSA:2.40.50.140 2 82 5.1E-23 T 29-03-2018 HVS_RS07235 866c5238fe8080acfc67b686908ef03c 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.4E-18 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HVS_RS07235 866c5238fe8080acfc67b686908ef03c 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 21.67 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HVS_RS07235 866c5238fe8080acfc67b686908ef03c 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 95 2.1E-27 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HVS_RS07235 866c5238fe8080acfc67b686908ef03c 95 SUPERFAMILY SSF141000 3 93 2.09E-28 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HVS_RS10485 345472959070167213149f3baf0b515a 424 Pfam PF05193 Peptidase M16 inactive domain 179 358 1.7E-18 T 29-03-2018 IPR007863 Peptidase M16, C-terminal HVS_RS10485 345472959070167213149f3baf0b515a 424 Gene3D G3DSA:3.30.830.10 2 219 6.3E-47 T 29-03-2018 HVS_RS10485 345472959070167213149f3baf0b515a 424 Gene3D G3DSA:3.30.830.10 220 424 4.1E-20 T 29-03-2018 HVS_RS10485 345472959070167213149f3baf0b515a 424 Pfam PF00675 Insulinase (Peptidase family M16) 61 173 1.9E-16 T 29-03-2018 IPR011765 Peptidase M16, N-terminal HVS_RS10485 345472959070167213149f3baf0b515a 424 SUPERFAMILY SSF63411 278 423 6.67E-17 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HVS_RS10485 345472959070167213149f3baf0b515a 424 SUPERFAMILY SSF63411 13 219 5.24E-42 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HVS_RS07840 3753421ec89db6d319c490c5be40926a 82 Pfam PF08753 NikR C terminal nickel binding domain 6 75 3.6E-5 T 29-03-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal HVS_RS07840 3753421ec89db6d319c490c5be40926a 82 Gene3D G3DSA:3.30.70.1150 5 79 4.6E-27 T 29-03-2018 HVS_RS07840 3753421ec89db6d319c490c5be40926a 82 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 5 80 7.2E-34 T 29-03-2018 IPR023860 [FeFe]-hydrogenase system regulator TM1266 HVS_RS07840 3753421ec89db6d319c490c5be40926a 82 SUPERFAMILY SSF55021 4 80 2.65E-27 T 29-03-2018 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 Pfam PF03102 NeuB family 26 290 7.3E-90 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 Pfam PF08666 SAF domain 308 358 1.1E-7 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 Gene3D G3DSA:3.20.20.70 1 292 4.2E-87 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 6 358 2.4E-134 T 29-03-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|KEGG: 00900+2.5.1.10|MetaCyc: PWY-5123|MetaCyc: PWY-6749|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7131|MetaCyc: PWY-7721|MetaCyc: PWY-7736 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 SUPERFAMILY SSF51569 3 159 7.75E-82 T 29-03-2018 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 SUPERFAMILY SSF51569 187 318 7.75E-82 T 29-03-2018 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 SUPERFAMILY SSF51269 298 358 1.57E-18 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 HVS_RS09835 3965d04619f7793b1c6092f90b14c61a 360 Gene3D G3DSA:3.90.1210.10 293 360 1.6E-21 T 29-03-2018 HVS_RS15940 f181ae34ae19fdb89dc25e4570f8d9d6 263 Gene3D G3DSA:3.60.15.10 9 260 2.4E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS15940 f181ae34ae19fdb89dc25e4570f8d9d6 263 SMART SM00849 12 192 4.1E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS15940 f181ae34ae19fdb89dc25e4570f8d9d6 263 SUPERFAMILY SSF56281 2 240 1.31E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS15940 f181ae34ae19fdb89dc25e4570f8d9d6 263 Pfam PF12706 Beta-lactamase superfamily domain 25 217 1.5E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS02680 417cb5b8746971d0d0bdefdb0ef7c486 104 SUPERFAMILY SSF54862 4 61 2.19E-15 T 29-03-2018 HVS_RS02680 417cb5b8746971d0d0bdefdb0ef7c486 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS02680 417cb5b8746971d0d0bdefdb0ef7c486 104 Gene3D G3DSA:3.30.70.20 46 85 0.0019 T 29-03-2018 HVS_RS02680 417cb5b8746971d0d0bdefdb0ef7c486 104 Gene3D G3DSA:3.30.70.20 1 45 4.8E-13 T 29-03-2018 HVS_RS02680 417cb5b8746971d0d0bdefdb0ef7c486 104 Pfam PF13187 4Fe-4S dicluster domain 9 56 5.0E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 Gene3D G3DSA:1.10.580.10 14 315 1.2E-81 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 PIRSF PIRSF001369 49 455 3.9E-90 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 Gene3D G3DSA:1.10.580.10 376 436 4.9E-11 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 PRINTS PR00143 Citrate synthase signature 388 404 9.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 PRINTS PR00143 Citrate synthase signature 408 422 9.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 PRINTS PR00143 Citrate synthase signature 235 250 9.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 PRINTS PR00143 Citrate synthase signature 179 192 9.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 PRINTS PR00143 Citrate synthase signature 258 286 9.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 Pfam PF00285 Citrate synthase, C-terminal domain 47 439 3.2E-122 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS02380 3499f4c5da6178d1282ce4ef770a3786 455 SUPERFAMILY SSF48256 58 444 5.89E-103 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 HVS_RS16085 cad841257874c8cc724c72fb9478aaed 253 SUPERFAMILY SSF55383 26 109 1.19E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16085 cad841257874c8cc724c72fb9478aaed 253 Gene3D G3DSA:3.30.457.10 36 96 1.0E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16085 cad841257874c8cc724c72fb9478aaed 253 Gene3D G3DSA:3.30.457.10 4 35 1.6E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16085 cad841257874c8cc724c72fb9478aaed 253 Gene3D G3DSA:3.30.457.10 97 185 2.5E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16085 cad841257874c8cc724c72fb9478aaed 253 Pfam PF07833 Copper amine oxidase N-terminal domain 23 115 5.0E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 SUPERFAMILY SSF50156 126 220 1.3E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 87 401 5.2E-99 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 Gene3D G3DSA:3.30.750.44 51 142 3.9E-15 T 29-03-2018 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 SMART SM00245 210 396 4.3E-58 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 Pfam PF03572 Peptidase family S41 235 395 1.8E-53 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 Gene3D G3DSA:2.30.42.10 143 224 5.8E-16 T 29-03-2018 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 SMART SM00228 135 208 3.9E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 SUPERFAMILY SSF52096 229 401 1.51E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 SUPERFAMILY SSF52096 71 154 1.51E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 Pfam PF13180 PDZ domain 136 214 3.3E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS14330 2f8a87a6a838a9007e2aa6ab343d65e3 431 Gene3D G3DSA:3.90.226.10 225 430 1.2E-67 T 29-03-2018 HVS_RS12020 958d5808a733665fc20ee858b203265f 499 Gene3D G3DSA:2.30.38.10 311 395 1.1E-21 T 29-03-2018 HVS_RS12020 958d5808a733665fc20ee858b203265f 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 29-03-2018 IPR020845 AMP-binding, conserved site HVS_RS12020 958d5808a733665fc20ee858b203265f 499 Gene3D G3DSA:3.40.50.980 2 160 2.6E-31 T 29-03-2018 HVS_RS12020 958d5808a733665fc20ee858b203265f 499 Pfam PF00501 AMP-binding enzyme 10 402 1.4E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS12020 958d5808a733665fc20ee858b203265f 499 Gene3D G3DSA:3.40.50.980 161 310 6.6E-40 T 29-03-2018 HVS_RS12020 958d5808a733665fc20ee858b203265f 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 486 2.0E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain HVS_RS12020 958d5808a733665fc20ee858b203265f 499 Gene3D G3DSA:3.30.300.30 397 497 2.6E-23 T 29-03-2018 HVS_RS12020 958d5808a733665fc20ee858b203265f 499 SUPERFAMILY SSF56801 5 495 8.77E-128 T 29-03-2018 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 522 1.5E-231 T 29-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 SMART SM00917 374 516 4.6E-44 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 Pfam PF08502 LeuA allosteric (dimerisation) domain 375 515 3.4E-31 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 202 215 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 SUPERFAMILY SSF110921 413 512 4.97E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 SUPERFAMILY SSF51569 2 292 4.21E-80 T 29-03-2018 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 Pfam PF00682 HMGL-like 3 252 4.0E-51 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HVS_RS01160 7f103cdbe2c4c0f5161f6da97520aa21 525 Gene3D G3DSA:3.20.20.70 1 333 1.1E-101 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS10490 34405ff4293e9b36bd88635ec0c08a08 432 Gene3D G3DSA:3.30.830.10 245 429 4.4E-29 T 29-03-2018 HVS_RS10490 34405ff4293e9b36bd88635ec0c08a08 432 SUPERFAMILY SSF63411 17 229 5.3E-19 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HVS_RS10490 34405ff4293e9b36bd88635ec0c08a08 432 Pfam PF05193 Peptidase M16 inactive domain 189 363 8.7E-25 T 29-03-2018 IPR007863 Peptidase M16, C-terminal HVS_RS10490 34405ff4293e9b36bd88635ec0c08a08 432 SUPERFAMILY SSF63411 252 419 6.38E-26 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HVS_RS10490 34405ff4293e9b36bd88635ec0c08a08 432 Gene3D G3DSA:3.30.830.10 11 235 1.3E-17 T 29-03-2018 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 7.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 7.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 7.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 7.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 7.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 7.2E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 PIRSF PIRSF002133 1 137 2.3E-48 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 SUPERFAMILY SSF50249 3 136 2.83E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.535 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 Gene3D G3DSA:2.40.50.140 1 140 4.3E-62 T 29-03-2018 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 4.2E-65 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12940 3a856c3470e9d40b9522119eb3c917ae 140 Pfam PF00164 Ribosomal protein S12/S23 37 136 1.0E-37 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 Pfam PF00005 ABC transporter 23 65 1.1E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 Pfam PF00005 ABC transporter 305 429 9.7E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 Pfam PF12848 ABC transporter 165 267 2.4E-8 T 29-03-2018 IPR032781 ABC-transporter extension domain HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 PRINTS PR00364 Disease resistance protein signature 31 46 1.7E-5 T 29-03-2018 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 PRINTS PR00364 Disease resistance protein signature 536 546 1.7E-5 T 29-03-2018 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 SMART SM00382 28 178 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 SMART SM00382 313 474 1.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 SUPERFAMILY SSF52540 280 487 1.42E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 Gene3D G3DSA:3.40.50.300 250 508 2.3E-49 T 29-03-2018 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 ProSitePatterns PS00211 ABC transporters family signature. 98 112 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 Gene3D G3DSA:3.40.50.300 2 220 8.9E-38 T 29-03-2018 HVS_RS12535 1388f33de7357fef1e36c75efe836420 546 SUPERFAMILY SSF52540 4 187 5.5E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13230 f236f6a4e3e6773b4484a610638a2e3a 76 Pfam PF14192 Domain of unknown function (DUF4314) 9 76 2.8E-32 T 29-03-2018 IPR025463 Domain of unknown function DUF4314 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 Gene3D G3DSA:2.60.420.10 727 811 1.2E-31 T 29-03-2018 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 SMART SM01068 1 63 2.2E-21 T 29-03-2018 IPR009342 Putative carbohydrate binding domain HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 SUPERFAMILY SSF74650 1 265 5.02E-86 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 Pfam PF06165 Glycosyltransferase family 36 21 263 2.4E-87 T 29-03-2018 IPR010383 Glycosyl hydrolase 94 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 Gene3D G3DSA:2.70.98.40 1 269 1.2E-93 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 Gene3D G3DSA:1.50.10.10 322 703 1.4E-79 T 29-03-2018 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 SUPERFAMILY SSF48208 286 811 5.1E-114 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 Gene3D G3DSA:1.20.890.20 270 313 2.9E-19 T 29-03-2018 HVS_RS14450 7d05a44a15eeb152dfc6bec097e5d6c4 811 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 307 737 1.5E-186 T 29-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 PIRSF PIRSF000446 1 310 5.4E-103 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 Pfam PF00698 Acyl transferase domain 6 284 7.1E-35 T 29-03-2018 IPR014043 Acyl transferase HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 Gene3D G3DSA:3.40.366.10 3 142 1.9E-37 T 29-03-2018 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 Gene3D G3DSA:3.30.70.250 143 184 3.7E-22 T 29-03-2018 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 SUPERFAMILY SSF55048 127 196 3.27E-18 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 305 9.9E-30 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 Gene3D G3DSA:3.40.366.10 185 309 6.4E-30 T 29-03-2018 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 1.8E-103 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 SUPERFAMILY SSF52151 189 307 1.12E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HVS_RS08825 7f2c781cecb90e681f67bfe92579f0e2 311 SUPERFAMILY SSF52151 4 121 1.12E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HVS_RS03115 99f53d38d702d75778c0c3283aa53ec7 193 Pfam PF13005 zinc-finger binding domain of transposase IS66 4 34 5.8E-8 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 HVS_RS03115 99f53d38d702d75778c0c3283aa53ec7 193 Pfam PF03050 Transposase IS66 family 55 193 6.2E-43 T 29-03-2018 IPR004291 Transposase, IS66 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 Pfam PF13353 4Fe-4S single cluster domain 16 146 2.1E-21 T 29-03-2018 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 SMART SM00729 20 234 4.3E-5 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 Pfam PF04055 Radical SAM superfamily 24 186 1.2E-35 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 SUPERFAMILY SSF102114 23 213 1.23E-36 T 29-03-2018 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 Gene3D G3DSA:3.80.30.10 68 237 1.2E-45 T 29-03-2018 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 235 2.8E-104 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 HVS_RS10075 6160c67fc74776e9cdf1e559f942a54f 238 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 HVS_RS06135 6d72cc81984c5f8a40b4ea12e348ac51 632 Pfam PF13727 CoA-binding domain 80 253 8.0E-19 T 29-03-2018 HVS_RS06135 6d72cc81984c5f8a40b4ea12e348ac51 632 Gene3D G3DSA:3.40.50.720 291 617 1.4E-71 T 29-03-2018 HVS_RS06135 6d72cc81984c5f8a40b4ea12e348ac51 632 SUPERFAMILY SSF53335 124 347 4.32E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS06135 6d72cc81984c5f8a40b4ea12e348ac51 632 Pfam PF02719 Polysaccharide biosynthesis protein 298 580 6.1E-129 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain HVS_RS06135 6d72cc81984c5f8a40b4ea12e348ac51 632 Gene3D G3DSA:3.40.50.720 152 279 1.6E-32 T 29-03-2018 HVS_RS06135 6d72cc81984c5f8a40b4ea12e348ac51 632 SUPERFAMILY SSF51735 297 596 7.33E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12235 ebc14774c2ab60c85dd55a892fd184ed 225 SMART SM00382 31 217 3.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12235 ebc14774c2ab60c85dd55a892fd184ed 225 Pfam PF00005 ABC transporter 22 168 6.0E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12235 ebc14774c2ab60c85dd55a892fd184ed 225 SUPERFAMILY SSF52540 3 221 3.76E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12235 ebc14774c2ab60c85dd55a892fd184ed 225 Gene3D G3DSA:3.40.50.300 1 223 4.9E-64 T 29-03-2018 HVS_RS12235 ebc14774c2ab60c85dd55a892fd184ed 225 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 Gene3D G3DSA:3.40.50.300 167 445 1.3E-75 T 29-03-2018 HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 9.6E-36 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 SUPERFAMILY SSF48024 8 120 5.36E-37 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 Pfam PF03796 DnaB-like helicase C terminal domain 185 439 7.8E-119 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 441 3.5E-187 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 SUPERFAMILY SSF52540 183 432 1.03E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01315 9da9206ed41bb5531af5068c882d3933 445 Gene3D G3DSA:1.10.860.10 4 151 8.8E-48 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 Pfam PF00202 Aminotransferase class-III 20 395 1.4E-135 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 Gene3D G3DSA:3.90.1150.10 292 398 5.2E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 Gene3D G3DSA:3.90.1150.10 2 169 3.8E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 SUPERFAMILY SSF53383 15 396 2.89E-138 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 PIRSF PIRSF000521 9 162 7.8E-12 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 PIRSF PIRSF000521 170 398 2.8E-45 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 396 46.8 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 Gene3D G3DSA:3.40.640.10 170 291 3.2E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 5 394 3.4E-114 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS14375 d20092f9a64e42f18045b4e4a58f0931 398 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 395 4.4E-160 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HVS_RS15305 5a73aea9ddcf87cf9067c573a6391e42 328 Pfam PF01343 Peptidase family S49 125 272 2.6E-53 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 HVS_RS15305 5a73aea9ddcf87cf9067c573a6391e42 328 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 53 270 2.2E-70 T 29-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 HVS_RS15305 5a73aea9ddcf87cf9067c573a6391e42 328 Gene3D G3DSA:3.90.226.10 44 313 2.1E-42 T 29-03-2018 HVS_RS15305 5a73aea9ddcf87cf9067c573a6391e42 328 SUPERFAMILY SSF52096 199 260 5.47E-44 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS15305 5a73aea9ddcf87cf9067c573a6391e42 328 SUPERFAMILY SSF52096 48 170 5.47E-44 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Gene3D G3DSA:3.90.182.10 664 701 5.8E-6 T 29-03-2018 HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Gene3D G3DSA:3.90.182.10 621 663 7.4E-13 T 29-03-2018 HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Pfam PF00395 S-layer homology domain 44 87 5.1E-9 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Pfam PF00395 S-layer homology domain 110 149 2.1E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Pfam PF00395 S-layer homology domain 171 212 2.2E-7 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 SUPERFAMILY SSF103647 589 689 1.06E-9 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 SUPERFAMILY SSF103647 453 527 3.01E-5 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Gene3D G3DSA:3.90.182.10 219 528 8.3E-21 T 29-03-2018 HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 Gene3D G3DSA:3.90.182.10 553 620 1.7E-8 T 29-03-2018 HVS_RS03140 73895bfd06919fb56d2563d136d001da 701 SUPERFAMILY SSF49265 242 327 9.73E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 PRINTS PR01100 Shikimate kinase family signature 94 111 9.3E-17 T 29-03-2018 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 PRINTS PR01100 Shikimate kinase family signature 4 19 9.3E-17 T 29-03-2018 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 PRINTS PR01100 Shikimate kinase family signature 28 41 9.3E-17 T 29-03-2018 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 PRINTS PR01100 Shikimate kinase family signature 73 82 9.3E-17 T 29-03-2018 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 Gene3D G3DSA:3.40.50.300 1 170 1.1E-26 T 29-03-2018 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 Pfam PF01202 Shikimate kinase 11 157 4.6E-32 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 SUPERFAMILY SSF52540 2 157 3.74E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08000 1db2d648b6fc3d4734dbdc6c4f52ec52 170 Hamap MF_00109 Shikimate kinase [aroK]. 1 162 20.904 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 HVS_RS08765 78833a8a8efcdfce64bd15b4b71c8907 196 Gene3D G3DSA:3.40.50.300 2 194 5.4E-36 T 29-03-2018 HVS_RS08765 78833a8a8efcdfce64bd15b4b71c8907 196 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 187 3.5E-44 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HVS_RS08765 78833a8a8efcdfce64bd15b4b71c8907 196 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 21.774 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HVS_RS08765 78833a8a8efcdfce64bd15b4b71c8907 196 Pfam PF01121 Dephospho-CoA kinase 3 180 7.9E-45 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 HVS_RS08765 78833a8a8efcdfce64bd15b4b71c8907 196 SUPERFAMILY SSF52540 2 190 1.05E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 353 9.6E-104 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 Gene3D G3DSA:3.40.50.300 1 366 3.0E-30 T 29-03-2018 HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 352 2.0E-16 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 SUPERFAMILY SSF52540 243 348 1.82E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 SUPERFAMILY SSF52540 2 216 1.82E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 367 88.045 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HVS_RS00020 eeb364cbddbf766e065b1cd95aeea448 367 ProSitePatterns PS00618 RecF protein signature 2. 311 329 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 HVS_RS11800 0f7ca21724eb90c4d2373ccc33f3c1ee 420 Gene3D G3DSA:3.20.20.80 81 420 7.1E-19 T 29-03-2018 HVS_RS11800 0f7ca21724eb90c4d2373ccc33f3c1ee 420 Pfam PF13200 Putative glycosyl hydrolase domain 86 413 5.7E-115 T 29-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 HVS_RS11800 0f7ca21724eb90c4d2373ccc33f3c1ee 420 SUPERFAMILY SSF51445 135 288 2.05E-11 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 10 34 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 208 236 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 119 136 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 169 193 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 78 106 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 243 269 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 PRINTS PR01874 DNA repair protein radA signature 317 340 7.2E-90 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 Pfam PF06745 KaiC 70 143 2.5E-12 T 29-03-2018 IPR014774 KaiC-like domain HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 Gene3D G3DSA:3.30.230.10 256 455 3.6E-39 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 4.8E-190 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 SMART SM00382 86 239 6.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 SUPERFAMILY SSF52540 63 286 3.67E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 Gene3D G3DSA:3.40.50.300 59 255 1.3E-23 T 29-03-2018 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 43.958 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 351 454 7.0E-10 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 SUPERFAMILY SSF54211 298 454 3.45E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS12600 52728ecc7bf06ad49a706fa90eac25e2 455 SUPERFAMILY SSF54211 250 264 3.45E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Pfam PF11799 impB/mucB/samB family C-terminal domain 245 348 3.7E-15 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Hamap MF_01113 DNA polymerase IV [dinB]. 2 356 33.543 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Gene3D G3DSA:3.30.70.270 118 170 2.6E-14 T 29-03-2018 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Gene3D G3DSA:3.30.70.270 43 117 4.4E-17 T 29-03-2018 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 SUPERFAMILY SSF56672 2 236 2.4E-74 T 29-03-2018 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Gene3D G3DSA:3.30.1490.100 245 358 2.5E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Pfam PF00817 impB/mucB/samB family 9 155 2.0E-44 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 Gene3D G3DSA:1.10.150.20 171 244 1.2E-16 T 29-03-2018 HVS_RS04800 8b78845f76c3735cdf0a67b56b392335 413 SUPERFAMILY SSF100879 245 344 1.86E-18 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 HVS_RS14000 b5e6b69c01fb1437435a99c1f2544aad 116 Gene3D G3DSA:2.30.30.110 1 116 3.1E-39 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS14000 b5e6b69c01fb1437435a99c1f2544aad 116 SUPERFAMILY SSF50118 3 113 6.54E-42 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS14000 b5e6b69c01fb1437435a99c1f2544aad 116 PIRSF PIRSF033490 1 113 1.4E-36 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HVS_RS14000 b5e6b69c01fb1437435a99c1f2544aad 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 1.3E-33 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 SMART SM00267 1 163 2.0E-49 T 29-03-2018 IPR000160 GGDEF domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 Pfam PF00563 EAL domain 179 415 2.5E-74 T 29-03-2018 IPR001633 EAL domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 Gene3D G3DSA:3.20.20.450 172 428 3.7E-97 T 29-03-2018 IPR001633 EAL domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 SUPERFAMILY SSF55073 7 164 3.22E-47 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1 161 1.2E-43 T 29-03-2018 IPR000160 GGDEF domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 SUPERFAMILY SSF141868 179 423 1.11E-86 T 29-03-2018 IPR001633 EAL domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 Pfam PF00990 Diguanylate cyclase, GGDEF domain 2 159 8.5E-49 T 29-03-2018 IPR000160 GGDEF domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 SMART SM00052 173 420 1.9E-104 T 29-03-2018 IPR001633 EAL domain HVS_RS02205 2b2c97f5a9e8564d464ebc466e4b6d61 431 Gene3D G3DSA:3.30.70.270 3 171 2.9E-56 T 29-03-2018 HVS_RS07665 725b5c5cbd4adade6371951b4190c763 284 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 197 260 1.6E-28 T 29-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal HVS_RS07665 725b5c5cbd4adade6371951b4190c763 284 Gene3D G3DSA:3.40.50.970 71 284 6.9E-48 T 29-03-2018 HVS_RS07665 725b5c5cbd4adade6371951b4190c763 284 Gene3D G3DSA:3.40.50.970 2 70 2.1E-11 T 29-03-2018 HVS_RS07665 725b5c5cbd4adade6371951b4190c763 284 SUPERFAMILY SSF52518 8 258 1.08E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS07665 725b5c5cbd4adade6371951b4190c763 284 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 12 269 6.3E-118 T 29-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate HVS_RS07665 725b5c5cbd4adade6371951b4190c763 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 193 4.5E-28 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS15115 1d50f53febc932eb9484872600d92450 158 ProSitePatterns PS00464 Ribosomal protein L22 signature. 130 154 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15115 1d50f53febc932eb9484872600d92450 158 Gene3D G3DSA:3.90.470.10 12 158 6.3E-43 T 29-03-2018 HVS_RS15115 1d50f53febc932eb9484872600d92450 158 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 48 157 27.646 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15115 1d50f53febc932eb9484872600d92450 158 Pfam PF00237 Ribosomal protein L22p/L17e 52 155 7.2E-37 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HVS_RS15115 1d50f53febc932eb9484872600d92450 158 SUPERFAMILY SSF54843 51 158 6.54E-42 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HVS_RS15115 1d50f53febc932eb9484872600d92450 158 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 52 154 5.8E-41 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS13145 279936cd2fe4b92f1df7cf99b8854f20 728 Gene3D G3DSA:1.25.10.10 330 513 5.8E-15 T 29-03-2018 IPR011989 Armadillo-like helical HVS_RS13145 279936cd2fe4b92f1df7cf99b8854f20 728 Gene3D G3DSA:1.25.10.10 514 715 1.0E-9 T 29-03-2018 IPR011989 Armadillo-like helical HVS_RS13145 279936cd2fe4b92f1df7cf99b8854f20 728 Gene3D G3DSA:1.20.5.340 15 89 0.003 T 29-03-2018 HVS_RS13145 279936cd2fe4b92f1df7cf99b8854f20 728 Gene3D G3DSA:1.20.5.340 90 249 0.067 T 29-03-2018 HVS_RS13145 279936cd2fe4b92f1df7cf99b8854f20 728 SUPERFAMILY SSF57997 35 198 1.7E-6 T 29-03-2018 HVS_RS13145 279936cd2fe4b92f1df7cf99b8854f20 728 SUPERFAMILY SSF48371 361 630 1.82E-16 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 HVS_RS15995 57c007beefc81f1d5b6d0533f65eb39e 143 Gene3D G3DSA:3.10.580.10 1 129 2.6E-32 T 29-03-2018 HVS_RS15995 57c007beefc81f1d5b6d0533f65eb39e 143 SMART SM00116 75 122 9.1E-10 T 29-03-2018 IPR000644 CBS domain HVS_RS15995 57c007beefc81f1d5b6d0533f65eb39e 143 SMART SM00116 10 57 8.8E-9 T 29-03-2018 IPR000644 CBS domain HVS_RS15995 57c007beefc81f1d5b6d0533f65eb39e 143 Pfam PF00571 CBS domain 68 119 1.8E-14 T 29-03-2018 IPR000644 CBS domain HVS_RS15995 57c007beefc81f1d5b6d0533f65eb39e 143 Pfam PF00571 CBS domain 3 53 8.8E-13 T 29-03-2018 IPR000644 CBS domain HVS_RS15995 57c007beefc81f1d5b6d0533f65eb39e 143 SUPERFAMILY SSF54631 1 118 1.02E-35 T 29-03-2018 HVS_RS10405 22a494ee10d0a5c2ffe81e26b160a91e 74 SMART SM00899 4 72 1.3E-13 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HVS_RS10405 22a494ee10d0a5c2ffe81e26b160a91e 74 SUPERFAMILY SSF50037 6 73 2.29E-12 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal HVS_RS10405 22a494ee10d0a5c2ffe81e26b160a91e 74 Gene3D G3DSA:2.30.30.90 8 74 2.6E-14 T 29-03-2018 HVS_RS10405 22a494ee10d0a5c2ffe81e26b160a91e 74 Pfam PF04023 FeoA domain 8 71 8.5E-14 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 Gene3D G3DSA:1.10.287.950 331 536 5.7E-47 T 29-03-2018 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 345 499 6.8E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 164 6.3E-28 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 Gene3D G3DSA:1.10.287.950 219 329 8.4E-11 T 29-03-2018 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 Pfam PF00672 HAMP domain 193 242 1.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 SUPERFAMILY SSF58104 305 533 1.44E-65 T 29-03-2018 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 SUPERFAMILY SSF58104 213 247 1.44E-65 T 29-03-2018 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 SMART SM00283 285 532 2.8E-83 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 Gene3D G3DSA:1.20.120.30 5 165 1.2E-23 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain HVS_RS11435 a9dcc8b24e64e2b6792c51c7eca926b3 595 SMART SM00304 193 245 7.9E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS04600 015a8cd1f66dd497a2755b8e2aa8b2eb 81 Pfam PF01610 Transposase 8 58 2.2E-8 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS12705 0dd914b4aa885f31a875f28e36b67585 362 Pfam PF03422 Carbohydrate binding module (family 6) 50 154 1.1E-5 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS12705 0dd914b4aa885f31a875f28e36b67585 362 Gene3D G3DSA:2.60.120.260 160 285 9.0E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12705 0dd914b4aa885f31a875f28e36b67585 362 Gene3D G3DSA:2.60.120.260 30 159 2.5E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12705 0dd914b4aa885f31a875f28e36b67585 362 SUPERFAMILY SSF49785 165 280 8.93E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12705 0dd914b4aa885f31a875f28e36b67585 362 SUPERFAMILY SSF49785 36 157 1.11E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12705 0dd914b4aa885f31a875f28e36b67585 362 Gene3D G3DSA:2.60.120.260 286 360 4.9E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 Gene3D G3DSA:3.40.50.620 1 179 1.0E-44 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 SUPERFAMILY SSF52374 15 175 2.68E-32 T 29-03-2018 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 Gene3D G3DSA:2.40.30.30 180 313 7.0E-40 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 Pfam PF06574 FAD synthetase 14 166 1.5E-46 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 308 5.1E-79 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 SUPERFAMILY SSF82114 174 308 2.11E-42 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 PIRSF PIRSF004491 1 312 4.1E-105 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 Pfam PF01687 Riboflavin kinase 184 307 4.2E-37 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 HVS_RS10500 35f8d15f435a2cb39fab78ca975c553f 313 SMART SM00904 183 308 1.4E-53 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 323 393 3.9E-27 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 Pfam PF04509 CheC-like family 38 73 1.0E-11 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 Pfam PF04509 CheC-like family 136 170 1.2E-12 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 Gene3D G3DSA:2.30.330.10 314 399 4.4E-29 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 PRINTS PR00956 Flagellar motor switch protein FliN signature 340 356 4.0E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 PRINTS PR00956 Flagellar motor switch protein FliN signature 323 339 4.0E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 PRINTS PR00956 Flagellar motor switch protein FliN signature 356 369 4.0E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 PRINTS PR00956 Flagellar motor switch protein FliN signature 369 384 4.0E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 Gene3D G3DSA:3.40.1550.10 1 86 1.5E-21 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 Gene3D G3DSA:3.40.1550.10 87 210 1.2E-32 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 SUPERFAMILY SSF103039 32 223 8.55E-49 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 SUPERFAMILY SSF101801 320 398 5.36E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) HVS_RS10195 7b66cfd4846cd60ac3a73ac6d12f6abb 399 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 320 395 7.2E-33 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 HVS_RS13440 c7f51102c2516d1d75222792bbbaac69 300 Pfam PF05368 NmrA-like family 3 225 1.2E-11 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 HVS_RS13440 c7f51102c2516d1d75222792bbbaac69 300 Gene3D G3DSA:3.40.50.720 2 129 8.4E-10 T 29-03-2018 HVS_RS13440 c7f51102c2516d1d75222792bbbaac69 300 Gene3D G3DSA:3.40.50.720 130 300 5.6E-14 T 29-03-2018 HVS_RS13440 c7f51102c2516d1d75222792bbbaac69 300 SUPERFAMILY SSF51735 2 286 4.55E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS02030 1ce4900cda253cf2a44f236ae269681d 437 Gene3D G3DSA:3.30.2400.10 163 315 1.6E-20 T 29-03-2018 HVS_RS02030 1ce4900cda253cf2a44f236ae269681d 437 Pfam PF05065 Phage capsid family 142 420 2.4E-39 T 29-03-2018 IPR024455 Phage capsid HVS_RS02030 1ce4900cda253cf2a44f236ae269681d 437 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 11 421 2.3E-55 T 29-03-2018 IPR024455 Phage capsid HVS_RS02030 1ce4900cda253cf2a44f236ae269681d 437 SUPERFAMILY SSF56563 142 420 2.75E-41 T 29-03-2018 HVS_RS01080 c10fda31ce1ef49fddcfec41733d28de 287 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 1.1E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01080 c10fda31ce1ef49fddcfec41733d28de 287 Gene3D G3DSA:3.30.457.10 66 127 3.1E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01080 c10fda31ce1ef49fddcfec41733d28de 287 Gene3D G3DSA:3.30.457.10 17 65 3.8E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01080 c10fda31ce1ef49fddcfec41733d28de 287 Gene3D G3DSA:3.30.457.10 128 265 2.6E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01080 c10fda31ce1ef49fddcfec41733d28de 287 SUPERFAMILY SSF55383 56 139 1.06E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11495 cfe4aeec57c1d7a31c9e24efeb8079ba 329 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 324 1.3E-142 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 HVS_RS11495 cfe4aeec57c1d7a31c9e24efeb8079ba 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 251 8.4E-62 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 HVS_RS11495 cfe4aeec57c1d7a31c9e24efeb8079ba 329 Gene3D G3DSA:3.90.25.10 164 329 2.9E-46 T 29-03-2018 HVS_RS11495 cfe4aeec57c1d7a31c9e24efeb8079ba 329 SUPERFAMILY SSF51735 3 325 4.48E-101 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS11495 cfe4aeec57c1d7a31c9e24efeb8079ba 329 Gene3D G3DSA:3.40.50.720 2 163 1.1E-35 T 29-03-2018 HVS_RS16050 c1e88f9a3e2eb4f36386457a5cc9a913 337 Pfam PF04754 Putative transposase, YhgA-like 9 211 2.3E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS16050 c1e88f9a3e2eb4f36386457a5cc9a913 337 Gene3D G3DSA:1.10.10.60 265 329 0.0014 T 29-03-2018 HVS_RS16050 c1e88f9a3e2eb4f36386457a5cc9a913 337 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 328 1.1E-15 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA HVS_RS13605 e54dd14c03a4f1901064403a7726ed89 68 SUPERFAMILY SSF160631 5 56 1.96E-7 T 29-03-2018 HVS_RS13605 e54dd14c03a4f1901064403a7726ed89 68 Gene3D G3DSA:3.40.1580.10 1 66 1.3E-6 T 29-03-2018 HVS_RS10175 ac33c65482cab0632c9598ae62850997 89 Pfam PF01313 Bacterial export proteins, family 3 5 78 4.4E-31 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HVS_RS10175 ac33c65482cab0632c9598ae62850997 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 2 88 4.8E-31 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 HVS_RS10175 ac33c65482cab0632c9598ae62850997 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 2.3E-20 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HVS_RS10175 ac33c65482cab0632c9598ae62850997 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 2.3E-20 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HVS_RS10175 ac33c65482cab0632c9598ae62850997 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 2.3E-20 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HVS_RS10175 ac33c65482cab0632c9598ae62850997 89 PIRSF PIRSF004669 1 89 5.4E-34 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 140 2.6E-30 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 PRINTS PR00207 Flagellin signature 74 93 9.0E-5 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 PRINTS PR00207 Flagellin signature 35 52 9.0E-5 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 PRINTS PR00207 Flagellin signature 109 132 9.0E-5 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 SUPERFAMILY SSF64518 1 303 7.32E-71 T 29-03-2018 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 194 7.1E-64 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 Gene3D G3DSA:1.20.1330.10 38 277 6.4E-45 T 29-03-2018 HVS_RS01390 ed9ee69b78d0a2c820861b207e2dc310 303 Pfam PF00700 Bacterial flagellin C-terminal helical region 219 301 3.2E-7 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HVS_RS14520 3e820de956e720d7b7670133f783f11c 613 Gene3D G3DSA:2.160.20.70 288 378 2.0E-10 T 29-03-2018 HVS_RS14520 3e820de956e720d7b7670133f783f11c 613 Gene3D G3DSA:2.160.20.70 485 611 6.6E-5 T 29-03-2018 HVS_RS14520 3e820de956e720d7b7670133f783f11c 613 Pfam PF03961 Flagellar Assembly Protein A 103 373 5.6E-64 T 29-03-2018 IPR005646 Flagellar assembly protein A HVS_RS08355 b87c3927921a65662632970bbbaa5939 167 SMART SM00506 1 133 9.8E-56 T 29-03-2018 IPR002589 Macro domain HVS_RS08355 b87c3927921a65662632970bbbaa5939 167 Gene3D G3DSA:3.40.220.10 1 167 5.0E-74 T 29-03-2018 HVS_RS08355 b87c3927921a65662632970bbbaa5939 167 SUPERFAMILY SSF52949 1 166 1.19E-69 T 29-03-2018 HVS_RS08355 b87c3927921a65662632970bbbaa5939 167 Pfam PF01661 Macro domain 17 133 8.5E-47 T 29-03-2018 IPR002589 Macro domain HVS_RS14665 1288b0bda93252f39e0d833063380e5e 257 SUPERFAMILY SSF53067 1 122 1.94E-36 T 29-03-2018 HVS_RS14665 1288b0bda93252f39e0d833063380e5e 257 SUPERFAMILY SSF53067 123 254 7.34E-39 T 29-03-2018 HVS_RS14665 1288b0bda93252f39e0d833063380e5e 257 Pfam PF03309 Type III pantothenate kinase 2 206 1.4E-71 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HVS_RS14665 1288b0bda93252f39e0d833063380e5e 257 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 37.162 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HVS_RS14665 1288b0bda93252f39e0d833063380e5e 257 Gene3D G3DSA:3.30.420.40 89 257 3.8E-63 T 29-03-2018 HVS_RS14665 1288b0bda93252f39e0d833063380e5e 257 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 251 3.4E-77 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 HVS_RS04910 447e3ebc245a65c542c2d0ed57e68f84 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS04910 447e3ebc245a65c542c2d0ed57e68f84 238 SUPERFAMILY SSF52540 5 230 1.33E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04910 447e3ebc245a65c542c2d0ed57e68f84 238 Gene3D G3DSA:3.40.50.300 3 237 3.9E-70 T 29-03-2018 HVS_RS04910 447e3ebc245a65c542c2d0ed57e68f84 238 Pfam PF00005 ABC transporter 22 165 3.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS04910 447e3ebc245a65c542c2d0ed57e68f84 238 SMART SM00382 31 213 2.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS07400 f3f4764c6c10747225cf5ec310361019 308 Pfam PF02562 PhoH-like protein 94 298 2.1E-98 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 HVS_RS07400 f3f4764c6c10747225cf5ec310361019 308 Gene3D G3DSA:3.30.1370.10 2 79 9.0E-4 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 HVS_RS07400 f3f4764c6c10747225cf5ec310361019 308 SUPERFAMILY SSF52540 8 273 1.72E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07400 f3f4764c6c10747225cf5ec310361019 308 Gene3D G3DSA:3.40.50.300 92 298 1.1E-30 T 29-03-2018 HVS_RS11185 116a8d67fdbe0a465fa399afbd3009a9 830 SUPERFAMILY SSF64182 65 462 1.01E-119 T 29-03-2018 HVS_RS11185 116a8d67fdbe0a465fa399afbd3009a9 830 Pfam PF01368 DHH family 90 238 8.4E-14 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS11185 116a8d67fdbe0a465fa399afbd3009a9 830 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 37 571 6.1E-186 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 HVS_RS11185 116a8d67fdbe0a465fa399afbd3009a9 830 Pfam PF02272 DHHA1 domain 327 450 2.1E-17 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HVS_RS11185 116a8d67fdbe0a465fa399afbd3009a9 830 Gene3D G3DSA:3.90.1640.10 71 253 1.7E-31 T 29-03-2018 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 SMART SM00387 356 464 6.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS13075 66df71efe8263141611fc811c15d033e 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 Gene3D G3DSA:3.30.565.10 305 464 1.8E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS13075 66df71efe8263141611fc811c15d033e 464 SUPERFAMILY SSF158472 192 240 5.23E-10 T 29-03-2018 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 461 1.5E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS13075 66df71efe8263141611fc811c15d033e 464 SUPERFAMILY SSF55874 300 462 1.07E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS13075 66df71efe8263141611fc811c15d033e 464 Pfam PF00672 HAMP domain 192 238 1.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 SMART SM00304 191 243 3.3E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 Gene3D G3DSA:1.10.287.130 234 304 2.1E-21 T 29-03-2018 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 SUPERFAMILY SSF47384 227 311 5.89E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 310 1.0E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 SMART SM00388 244 310 4.1E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS13075 66df71efe8263141611fc811c15d033e 464 Gene3D G3DSA:3.30.450.20 30 165 9.4E-12 T 29-03-2018 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 Gene3D G3DSA:3.30.420.40 4 148 3.2E-46 T 29-03-2018 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 Gene3D G3DSA:3.30.420.40 149 292 2.0E-19 T 29-03-2018 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 SUPERFAMILY SSF53067 6 126 2.59E-32 T 29-03-2018 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 318 1.1E-133 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 336 62.06 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 7.3E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 7.3E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 7.3E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 7.3E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 7.3E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 7.3E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 Pfam PF00814 Glycoprotease family 26 311 1.3E-102 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 SUPERFAMILY SSF53067 105 316 2.75E-45 T 29-03-2018 HVS_RS12855 5c06360309028bbddeeb35cb62d423ca 339 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 311 2.7E-110 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 SUPERFAMILY SSF53756 392 683 8.52E-6 T 29-03-2018 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 SUPERFAMILY SSF53756 3 370 7.63E-78 T 29-03-2018 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 Pfam PF04230 Polysaccharide pyruvyl transferase 393 673 1.4E-47 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 Pfam PF00534 Glycosyl transferases group 1 185 344 3.6E-35 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 Gene3D G3DSA:3.40.50.2000 1 176 1.2E-16 T 29-03-2018 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 383 691 2.7E-84 T 29-03-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 Gene3D G3DSA:3.40.50.2000 177 352 3.2E-41 T 29-03-2018 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 Gene3D G3DSA:3.40.50.2000 547 689 2.4E-7 T 29-03-2018 HVS_RS13985 dae2008c195fad4bf72729848939c93b 743 Pfam PF13439 Glycosyltransferase Family 4 12 168 1.5E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS07900 90f8ddd03ff0f6bc5d6cc3924d44df60 186 Gene3D G3DSA:2.60.60.30 7 179 2.8E-13 T 29-03-2018 HVS_RS07900 90f8ddd03ff0f6bc5d6cc3924d44df60 186 Pfam PF02342 TerD domain 3 177 1.4E-16 T 29-03-2018 IPR003325 TerD domain GO:0006950 HVS_RS09785 1524d198243ef623c50dc3574cd1acc4 122 Pfam PF13799 Domain of unknown function (DUF4183) 39 107 1.6E-14 T 29-03-2018 IPR025237 Domain of unknown function DUF4183 HVS_RS10045 61c841059e3c08f42da67ea882681834 728 Pfam PF07833 Copper amine oxidase N-terminal domain 71 163 2.6E-30 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10045 61c841059e3c08f42da67ea882681834 728 Gene3D G3DSA:3.30.457.10 17 83 1.0E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10045 61c841059e3c08f42da67ea882681834 728 Gene3D G3DSA:3.30.457.10 146 249 3.1E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10045 61c841059e3c08f42da67ea882681834 728 Gene3D G3DSA:3.30.457.10 84 145 9.2E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10045 61c841059e3c08f42da67ea882681834 728 SUPERFAMILY SSF55383 39 90 5.75E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10045 61c841059e3c08f42da67ea882681834 728 SUPERFAMILY SSF55383 74 158 1.22E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 SMART SM00342 214 297 1.0E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 SUPERFAMILY SSF46689 198 248 2.82E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 Gene3D G3DSA:1.10.10.60 267 302 6.4E-14 T 29-03-2018 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 281 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 297 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 Pfam PF12833 Helix-turn-helix domain 222 298 3.3E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 SUPERFAMILY SSF46689 251 301 5.82E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 Gene3D G3DSA:3.90.1240.10 95 266 1.3E-25 T 29-03-2018 HVS_RS01750 808654efd4f9be840c4bbb2eeeb0a7c5 303 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 251 293 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 Pfam PF13599 Pentapeptide repeats (9 copies) 236 294 2.1E-8 T 29-03-2018 IPR001646 Pentapeptide repeat HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 Pfam PF13599 Pentapeptide repeats (9 copies) 357 419 2.4E-6 T 29-03-2018 IPR001646 Pentapeptide repeat HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 Pfam PF13599 Pentapeptide repeats (9 copies) 300 355 5.6E-9 T 29-03-2018 IPR001646 Pentapeptide repeat HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 Gene3D G3DSA:2.160.10.20 351 419 2.2E-12 T 29-03-2018 HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 Gene3D G3DSA:2.160.10.20 307 350 1.2E-10 T 29-03-2018 HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 Gene3D G3DSA:2.160.20.80 192 306 4.4E-19 T 29-03-2018 HVS_RS10825 5c0564b81336dad3d2082b1e2c6c14bb 422 SUPERFAMILY SSF141571 214 347 4.78E-28 T 29-03-2018 HVS_RS11595 ee814c470c8884d59f09db081ab7c4f9 140 SMART SM00732 1 103 1.8E-34 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 HVS_RS11595 ee814c470c8884d59f09db081ab7c4f9 140 Pfam PF03652 Holliday junction resolvase 1 136 4.2E-44 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HVS_RS11595 ee814c470c8884d59f09db081ab7c4f9 140 Gene3D G3DSA:3.30.420.140 1 140 2.0E-44 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 HVS_RS11595 ee814c470c8884d59f09db081ab7c4f9 140 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 1.3E-40 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HVS_RS11595 ee814c470c8884d59f09db081ab7c4f9 140 SUPERFAMILY SSF53098 1 137 6.22E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS11595 ee814c470c8884d59f09db081ab7c4f9 140 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 26.174 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 14 416 1.9E-192 T 29-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 SUPERFAMILY SSF102114 107 352 1.44E-36 T 29-03-2018 HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 TIGRFAM TIGR00238 TIGR00238: KamA family protein 8 335 5.2E-121 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 Gene3D G3DSA:3.20.20.70 105 386 3.9E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 Pfam PF12544 Lysine-2,3-aminomutase 314 421 1.6E-40 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 PIRSF PIRSF004911 1 403 8.1E-168 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase HVS_RS06455 a77ec9c91627dc130cda4634b83780c0 425 Pfam PF04055 Radical SAM superfamily 123 269 5.6E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS06650 e7b05c60f1af94de74ed422ef6e2d6e2 167 Pfam PF13185 GAF domain 55 159 3.2E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 HVS_RS06650 e7b05c60f1af94de74ed422ef6e2d6e2 167 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 99 116 - T 29-03-2018 IPR000614 Free Met sulfoxide reductase conserved site HVS_RS06650 e7b05c60f1af94de74ed422ef6e2d6e2 167 Gene3D G3DSA:3.30.450.40 5 166 6.4E-22 T 29-03-2018 IPR029016 GAF domain-like HVS_RS06650 e7b05c60f1af94de74ed422ef6e2d6e2 167 SUPERFAMILY SSF55781 8 161 4.36E-42 T 29-03-2018 IPR029016 GAF domain-like HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 SMART SM00257 74 118 1.2E-17 T 29-03-2018 IPR018392 LysM domain HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 Pfam PF01476 LysM domain 75 118 6.0E-15 T 29-03-2018 IPR018392 LysM domain HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 Gene3D G3DSA:1.10.101.10 1 72 3.0E-23 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 Gene3D G3DSA:3.40.630.10 127 420 2.0E-47 T 29-03-2018 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 Pfam PF01471 Putative peptidoglycan binding domain 10 63 9.3E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 SMART SM00631 130 415 1.9E-23 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 173 187 6.3E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 329 342 6.3E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 271 279 6.3E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 154 166 6.3E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 SUPERFAMILY SSF53187 123 418 9.59E-56 T 29-03-2018 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 SUPERFAMILY SSF54106 74 119 1.14E-12 T 29-03-2018 IPR018392 LysM domain HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 Pfam PF00246 Zinc carboxypeptidase 137 413 4.3E-40 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 SUPERFAMILY SSF47090 2 65 1.96E-20 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS15380 87f747e7bc48f5455df826fc59c6f4bc 423 Gene3D G3DSA:3.10.350.10 73 119 5.4E-18 T 29-03-2018 HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 SUPERFAMILY SSF53686 1 485 1.51E-142 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 Gene3D G3DSA:3.90.1380.10 1 89 2.0E-22 T 29-03-2018 IPR029144 Threonine synthase, N-terminal HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 Pfam PF14821 Threonine synthase N terminus 3 79 4.3E-18 T 29-03-2018 IPR029144 Threonine synthase, N-terminal HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 95 406 1.5E-12 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 Gene3D G3DSA:3.40.50.1100 208 446 1.0E-81 T 29-03-2018 HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 TIGRFAM TIGR00260 thrC: threonine synthase 81 445 9.6E-81 T 29-03-2018 IPR004450 Threonine synthase-like HVS_RS11290 36976d26839acd34a3301f18e8d56b67 499 Gene3D G3DSA:3.40.50.1100 107 207 9.1E-16 T 29-03-2018 HVS_RS04120 e19905dd7cabe47d8f586681ac2cc690 482 Gene3D G3DSA:3.40.640.10 128 226 1.7E-4 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS04120 e19905dd7cabe47d8f586681ac2cc690 482 PIRSF PIRSF001386 9 464 3.1E-187 T 29-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 HVS_RS04120 e19905dd7cabe47d8f586681ac2cc690 482 Pfam PF01212 Beta-eliminating lyase 55 426 3.3E-59 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 HVS_RS04120 e19905dd7cabe47d8f586681ac2cc690 482 Gene3D G3DSA:3.90.1150.10 27 127 3.1E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS04120 e19905dd7cabe47d8f586681ac2cc690 482 Gene3D G3DSA:3.90.1150.10 280 461 2.7E-56 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS04120 e19905dd7cabe47d8f586681ac2cc690 482 SUPERFAMILY SSF53383 11 463 2.67E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS07430 6a9867725356a0964fd26a6da8254398 52 Pfam PF14006 YqzL-like protein 4 34 4.5E-12 T 29-03-2018 IPR025617 YqzL-like protein HVS_RS03700 d0c9cfb1dbae2c00711dafb53e3433dc 147 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 2 145 2.1E-46 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HVS_RS03700 d0c9cfb1dbae2c00711dafb53e3433dc 147 Pfam PF01867 CRISPR associated protein Cas1 1 109 1.5E-41 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 HVS_RS00265 d08c2d9eabc698bcc7361952a99f7450 201 SUPERFAMILY SSF55874 58 193 2.01E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS00265 d08c2d9eabc698bcc7361952a99f7450 201 Gene3D G3DSA:3.30.565.10 26 201 1.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS00265 d08c2d9eabc698bcc7361952a99f7450 201 Pfam PF06580 Histidine kinase 4 80 6.4E-22 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 HVS_RS07150 1ce6a93b1b94fa58ba4d2f46fe457571 367 Pfam PF04055 Radical SAM superfamily 81 230 2.3E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS07150 1ce6a93b1b94fa58ba4d2f46fe457571 367 SMART SM00876 256 359 3.5E-33 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS07150 1ce6a93b1b94fa58ba4d2f46fe457571 367 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 4 366 2.3E-147 T 29-03-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 HVS_RS07150 1ce6a93b1b94fa58ba4d2f46fe457571 367 Gene3D G3DSA:3.20.20.70 22 367 2.1E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS07150 1ce6a93b1b94fa58ba4d2f46fe457571 367 SUPERFAMILY SSF102114 36 331 3.53E-48 T 29-03-2018 HVS_RS07150 1ce6a93b1b94fa58ba4d2f46fe457571 367 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 256 358 1.5E-26 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS08670 c00d9c8dad95c45057e191e0c5a46834 64 Pfam PF06686 Stage III sporulation protein AC/AD protein family 6 61 3.9E-17 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family HVS_RS08670 c00d9c8dad95c45057e191e0c5a46834 64 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 1 64 1.1E-27 T 29-03-2018 IPR009570 Stage III sporulation protein AC HVS_RS07160 1eb24a35593fd990a6cc75b83a925e68 351 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 146 347 26.635 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HVS_RS07160 1eb24a35593fd990a6cc75b83a925e68 351 Pfam PF02581 Thiamine monophosphate synthase 148 329 1.7E-62 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HVS_RS07160 1eb24a35593fd990a6cc75b83a925e68 351 SUPERFAMILY SSF51391 141 343 8.24E-65 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HVS_RS07160 1eb24a35593fd990a6cc75b83a925e68 351 Gene3D G3DSA:3.20.20.70 137 346 5.0E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS07160 1eb24a35593fd990a6cc75b83a925e68 351 PIRSF PIRSF000512 1 350 2.3E-93 T 29-03-2018 IPR016229 Thiamine-phosphate synthase, cyanobacterial/bacterial GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HVS_RS07160 1eb24a35593fd990a6cc75b83a925e68 351 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 148 340 4.1E-67 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Gene3D G3DSA:2.60.40.10 188 317 0.0018 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Gene3D G3DSA:2.60.40.10 332 396 1.0E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Gene3D G3DSA:2.60.40.650 399 577 3.8E-4 T 29-03-2018 HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Gene3D G3DSA:2.60.40.10 627 746 2.5E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Pfam PF00395 S-layer homology domain 760 782 6.6E-6 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Pfam PF00395 S-layer homology domain 801 843 2.9E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03750 1f194a278e9621e7114f6532f4f4dd2a 962 Pfam PF00395 S-layer homology domain 861 905 2.1E-7 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS09135 7159a9a153edf3a33685cf0c1f20cc50 328 PIRSF PIRSF002849 1 328 4.3E-122 T 29-03-2018 HVS_RS09135 7159a9a153edf3a33685cf0c1f20cc50 328 Gene3D G3DSA:3.40.50.300 26 195 7.9E-29 T 29-03-2018 HVS_RS09135 7159a9a153edf3a33685cf0c1f20cc50 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 178 3.9E-64 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS09135 7159a9a153edf3a33685cf0c1f20cc50 328 SUPERFAMILY SSF52540 12 300 1.52E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09135 7159a9a153edf3a33685cf0c1f20cc50 328 Gene3D G3DSA:1.10.8.300 208 325 3.0E-24 T 29-03-2018 HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 16 431 2.7E-201 T 29-03-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 80 416 2.6E-50 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 PIRSF PIRSF001413 12 435 2.8E-126 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 SUPERFAMILY SSF53686 37 428 1.2E-116 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 27 429 41.797 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 Gene3D G3DSA:3.40.50.1100 92 217 9.7E-26 T 29-03-2018 HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 Gene3D G3DSA:3.40.50.1100 218 438 2.5E-36 T 29-03-2018 HVS_RS12295 24f73fcd4195cadda6bf783bfb91ccad 455 PIRSF PIRSF500824 4 438 4.5E-209 T 29-03-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 HVS_RS12180 712e6c6a4f482b6fb6baaab09dbf0925 202 Gene3D G3DSA:3.40.50.300 16 201 2.1E-60 T 29-03-2018 HVS_RS12180 712e6c6a4f482b6fb6baaab09dbf0925 202 SUPERFAMILY SSF52540 17 201 1.34E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12180 712e6c6a4f482b6fb6baaab09dbf0925 202 PIRSF PIRSF006135 15 202 5.7E-62 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS12180 712e6c6a4f482b6fb6baaab09dbf0925 202 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 17 200 5.9E-62 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 19 524 7.7E-233 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 SMART SM00471 336 442 1.8E-13 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS07285 9625fd5ca1c41973428871af96307143 524 Pfam PF00013 KH domain 217 274 2.0E-6 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 Pfam PF01966 HD domain 340 432 2.3E-20 T 29-03-2018 IPR006674 HD domain HVS_RS07285 9625fd5ca1c41973428871af96307143 524 Hamap MF_00335 Ribonuclease Y [rny]. 12 524 25.197 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 TIGRFAM TIGR00277 HDIG: HDIG domain 336 413 6.3E-26 T 29-03-2018 IPR006675 HDIG domain HVS_RS07285 9625fd5ca1c41973428871af96307143 524 SMART SM00322 212 279 7.1E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 Pfam PF12072 Domain of unknown function (DUF3552) 17 209 4.2E-62 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal HVS_RS07285 9625fd5ca1c41973428871af96307143 524 SUPERFAMILY SSF54791 215 308 1.12E-16 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 SUPERFAMILY SSF109604 320 474 4.26E-31 T 29-03-2018 HVS_RS07285 9625fd5ca1c41973428871af96307143 524 Gene3D G3DSA:3.30.300.20 50 248 7.4E-6 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS07285 9625fd5ca1c41973428871af96307143 524 Gene3D G3DSA:1.10.3210.10 249 480 1.0E-38 T 29-03-2018 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 463 491 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 Gene3D G3DSA:1.10.530.10 432 589 3.0E-36 T 29-03-2018 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 Pfam PF01464 Transglycosylase SLT domain 445 553 2.5E-28 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 Pfam PF14559 Tetratricopeptide repeat 200 252 8.3E-7 T 29-03-2018 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 SUPERFAMILY SSF53955 441 589 2.93E-40 T 29-03-2018 IPR023346 Lysozyme-like domain HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 Gene3D G3DSA:1.25.40.10 253 431 1.3E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 Gene3D G3DSA:1.25.40.10 161 250 2.0E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 SUPERFAMILY SSF48452 84 281 4.81E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 SUPERFAMILY SSF48452 401 431 4.81E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS03715 c22b1ecfcd66ddd2f567f0e386b3b202 591 Gene3D G3DSA:1.25.40.10 46 160 5.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS08910 18f83f907633524f027950090eef201d 308 SUPERFAMILY SSF53671 3 303 1.83E-96 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 302 5.0E-29 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 Gene3D G3DSA:3.40.50.1370 1 162 4.2E-60 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 305 39.348 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 303 1.0E-96 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 Gene3D G3DSA:3.40.50.1370 163 305 8.4E-47 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 148 1.5E-42 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 2.7E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 2.7E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 2.7E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 2.7E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 42 64 2.7E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 2.7E-30 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 5.3E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 5.3E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 5.3E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08910 18f83f907633524f027950090eef201d 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 5.3E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Gene3D G3DSA:2.40.50.140 996 1093 4.1E-15 T 29-03-2018 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 SMART SM00481 5 72 1.0E-29 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 296 719 5.6E-181 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Pfam PF01336 OB-fold nucleic acid binding domain 1016 1090 8.7E-8 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 SUPERFAMILY SSF160975 831 876 2.75E-5 T 29-03-2018 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1051 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Gene3D G3DSA:1.10.150.280 793 890 1.4E-12 T 29-03-2018 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Pfam PF14579 Helix-hairpin-helix motif 806 893 2.4E-27 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 SUPERFAMILY SSF89550 3 268 7.85E-42 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Gene3D G3DSA:3.20.20.140 2 253 2.7E-59 T 29-03-2018 HVS_RS10730 8929742398f511d45c2ade87f5f36be3 1171 Pfam PF02811 PHP domain 6 177 3.9E-55 T 29-03-2018 IPR004013 PHP domain GO:0003824 HVS_RS05245 79b2b62640ec52bfa22d1a28b8f38491 236 Gene3D G3DSA:1.10.4030.10 39 168 3.9E-23 T 29-03-2018 HVS_RS05245 79b2b62640ec52bfa22d1a28b8f38491 236 Pfam PF13624 SurA N-terminal domain 43 160 2.1E-16 T 29-03-2018 HVS_RS05245 79b2b62640ec52bfa22d1a28b8f38491 236 SUPERFAMILY SSF109998 46 184 3.73E-26 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS00275 0a804b700155ad22dff2719e68a59df5 353 SUPERFAMILY SSF69304 86 217 4.18E-5 T 29-03-2018 HVS_RS00275 0a804b700155ad22dff2719e68a59df5 353 Gene3D G3DSA:2.120.10.30 13 347 5.6E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like HVS_RS00275 0a804b700155ad22dff2719e68a59df5 353 Pfam PF16472 Domain of unknown function (DUF5050) 79 228 2.9E-12 T 29-03-2018 IPR032485 Domain of unknown function DUF5050 HVS_RS11085 5e9e2927ada0e64237192a4a3481773b 123 Gene3D G3DSA:3.40.50.2300 1 123 4.7E-36 T 29-03-2018 HVS_RS11085 5e9e2927ada0e64237192a4a3481773b 123 SMART SM00448 4 117 7.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS11085 5e9e2927ada0e64237192a4a3481773b 123 SUPERFAMILY SSF52172 1 122 5.41E-36 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS11085 5e9e2927ada0e64237192a4a3481773b 123 Pfam PF00072 Response regulator receiver domain 7 118 9.0E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS12335 f261b153cbff9b1c251cc430e5e1c6f6 327 Gene3D G3DSA:3.30.420.40 2 108 2.5E-4 T 29-03-2018 HVS_RS12335 f261b153cbff9b1c251cc430e5e1c6f6 327 SUPERFAMILY SSF53067 4 257 2.6E-41 T 29-03-2018 HVS_RS12335 f261b153cbff9b1c251cc430e5e1c6f6 327 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 5 256 2.8E-57 T 29-03-2018 IPR008275 CoA enzyme activase HVS_RS12335 f261b153cbff9b1c251cc430e5e1c6f6 327 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 257 2.4E-50 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HVS_RS12335 f261b153cbff9b1c251cc430e5e1c6f6 327 Gene3D G3DSA:3.30.420.40 109 242 1.9E-39 T 29-03-2018 HVS_RS15620 d0b784381e7c94787b7ff9fc4646fcdc 230 Pfam PF07290 Protein of unknown function (DUF1449) 104 225 8.3E-5 T 29-03-2018 IPR010840 Protein of unknown function DUF1449 HVS_RS15620 d0b784381e7c94787b7ff9fc4646fcdc 230 Gene3D G3DSA:1.10.287.70 3 151 8.2E-4 T 29-03-2018 HVS_RS15620 d0b784381e7c94787b7ff9fc4646fcdc 230 Gene3D G3DSA:2.40.50.140 152 228 1.8E-11 T 29-03-2018 HVS_RS01875 9572b122466ded7cc17f657238b39a03 429 Pfam PF02371 Transposase IS116/IS110/IS902 family 284 376 8.7E-27 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HVS_RS01875 9572b122466ded7cc17f657238b39a03 429 Pfam PF01548 Transposase 7 163 3.7E-34 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HVS_RS11090 900c3f872aeaca497b97bf01a00bcd81 248 Gene3D G3DSA:3.40.1280.10 1 247 1.0E-79 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS11090 900c3f872aeaca497b97bf01a00bcd81 248 Pfam PF04452 RNA methyltransferase 16 240 2.4E-72 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS11090 900c3f872aeaca497b97bf01a00bcd81 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 244 1.4E-64 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS11090 900c3f872aeaca497b97bf01a00bcd81 248 SUPERFAMILY SSF88697 1 66 2.14E-12 T 29-03-2018 IPR015947 PUA-like domain HVS_RS11090 900c3f872aeaca497b97bf01a00bcd81 248 PIRSF PIRSF015601 1 245 1.3E-72 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS11090 900c3f872aeaca497b97bf01a00bcd81 248 SUPERFAMILY SSF75217 73 245 2.53E-54 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS12330 71e449a002cda9407060ac87c753cd85 460 Gene3D G3DSA:3.40.190.10 234 452 1.2E-6 T 29-03-2018 HVS_RS12330 71e449a002cda9407060ac87c753cd85 460 Gene3D G3DSA:3.40.190.10 59 233 3.8E-23 T 29-03-2018 HVS_RS12330 71e449a002cda9407060ac87c753cd85 460 Pfam PF13416 Bacterial extracellular solute-binding protein 77 381 8.2E-23 T 29-03-2018 HVS_RS12330 71e449a002cda9407060ac87c753cd85 460 SUPERFAMILY SSF53850 61 452 7.76E-38 T 29-03-2018 HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 SUPERFAMILY SSF55594 3 87 9.94E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.3E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.3E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.3E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 Gene3D G3DSA:3.30.1340.10 1 87 2.2E-34 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 Pfam PF00381 PTS HPr component phosphorylation site 2 81 6.2E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS12085 c8008df2d68577a06223a71f5bdfec4f 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 6.8E-33 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 PIRSF PIRSF006816 1 255 6.9E-65 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 Gene3D G3DSA:2.40.30.10 1 91 1.1E-10 T 29-03-2018 HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 SUPERFAMILY SSF52343 89 248 1.29E-28 T 29-03-2018 HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 Gene3D G3DSA:2.10.240.10 213 249 8.0E-9 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 Gene3D G3DSA:3.40.50.80 99 203 5.3E-11 T 29-03-2018 HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 SUPERFAMILY SSF63380 1 90 1.49E-19 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HVS_RS11200 847844dfd771c14dbeaca621145bfc4c 281 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 249 4.4E-12 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 339 6.2E-106 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 SUPERFAMILY SSF46589 14 99 5.18E-21 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 SUPERFAMILY SSF55681 93 339 1.32E-80 T 29-03-2018 HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 Pfam PF01409 tRNA synthetases class II core domain (F) 93 339 5.7E-106 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 4.0E-25 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 339 47.701 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 HVS_RS11365 db4c0eaeb1962f891e551e2d7e1ef2ca 339 Gene3D G3DSA:3.30.930.10 8 339 4.9E-90 T 29-03-2018 HVS_RS05865 6df11c6ccf3b8f7858efb35c2306a473 530 Pfam PF03961 Flagellar Assembly Protein A 75 527 1.9E-103 T 29-03-2018 IPR005646 Flagellar assembly protein A HVS_RS05865 6df11c6ccf3b8f7858efb35c2306a473 530 Gene3D G3DSA:2.160.20.70 244 376 7.4E-8 T 29-03-2018 HVS_RS15010 6aa563b1370ce572851242be77816758 123 Gene3D G3DSA:1.10.8.50 1 67 1.7E-27 T 29-03-2018 HVS_RS15010 6aa563b1370ce572851242be77816758 123 Gene3D G3DSA:4.10.910.10 87 123 3.0E-26 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15010 6aa563b1370ce572851242be77816758 123 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15010 6aa563b1370ce572851242be77816758 123 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.1E-33 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15010 6aa563b1370ce572851242be77816758 123 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.2E-55 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15010 6aa563b1370ce572851242be77816758 123 Gene3D G3DSA:4.10.910.10 68 86 4.1E-19 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15010 6aa563b1370ce572851242be77816758 123 SUPERFAMILY SSF46946 2 115 3.27E-47 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HVS_RS15010 6aa563b1370ce572851242be77816758 123 PIRSF PIRSF002134 1 123 3.1E-45 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15010 6aa563b1370ce572851242be77816758 123 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 29.506 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 SUPERFAMILY SSF88659 106 167 9.16E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 SUPERFAMILY SSF88946 2 96 2.51E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 Pfam PF04542 Sigma-70 region 2 22 87 2.7E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 165 3.1E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 Gene3D G3DSA:1.10.1740.10 1 93 1.4E-22 T 29-03-2018 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 Pfam PF08281 Sigma-70, region 4 111 161 4.0E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS05315 0ecdd4ebe38f9536540573516d01ecd6 173 Gene3D G3DSA:1.10.10.10 96 169 5.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09860 cf791118c14f27b1764bc754da04f4a3 127 Pfam PF13799 Domain of unknown function (DUF4183) 53 122 1.4E-22 T 29-03-2018 IPR025237 Domain of unknown function DUF4183 HVS_RS07905 45bc2deaf47e171b15ab1eb8a7957906 192 Gene3D G3DSA:2.60.60.30 18 187 1.3E-65 T 29-03-2018 HVS_RS07905 45bc2deaf47e171b15ab1eb8a7957906 192 Pfam PF02342 TerD domain 1 188 2.6E-86 T 29-03-2018 IPR003325 TerD domain GO:0006950 HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 Gene3D G3DSA:1.10.132.20 434 534 0.045 T 29-03-2018 HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 Gene3D G3DSA:3.20.20.70 10 187 3.0E-10 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 Pfam PF12392 Collagenase 396 511 4.5E-27 T 29-03-2018 IPR020988 Peptidase U32, collagenase HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 ProSitePatterns PS01276 Peptidase family U32 signature. 164 182 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 Pfam PF01136 Peptidase family U32 614 826 6.6E-19 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 Pfam PF01136 Peptidase family U32 79 304 1.2E-80 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HVS_RS14550 5a3336382f15c9dcec9eabd7641e52a3 829 Gene3D G3DSA:3.20.20.70 535 709 0.0028 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS05645 39e38e6f992b793fef69c193d7afa809 96 SUPERFAMILY SSF140453 4 95 4.84E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS05645 39e38e6f992b793fef69c193d7afa809 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 92 4.6E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS05645 39e38e6f992b793fef69c193d7afa809 96 Pfam PF06013 Proteins of 100 residues with WXG 5 85 4.3E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS05645 39e38e6f992b793fef69c193d7afa809 96 Gene3D G3DSA:1.10.287.850 1 93 1.0E-16 T 29-03-2018 HVS_RS11740 5739777aedbdee28febdc5caf8d65605 265 Pfam PF13401 AAA domain 42 170 5.1E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11740 5739777aedbdee28febdc5caf8d65605 265 SUPERFAMILY SSF52540 15 250 1.19E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11740 5739777aedbdee28febdc5caf8d65605 265 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11740 5739777aedbdee28febdc5caf8d65605 265 Gene3D G3DSA:3.40.50.300 13 208 2.0E-10 T 29-03-2018 HVS_RS11045 b3951b8f2f57729a6dd8611be4fe1bf7 446 Gene3D G3DSA:2.120.10.10 23 148 7.4E-7 T 29-03-2018 HVS_RS11045 b3951b8f2f57729a6dd8611be4fe1bf7 446 Gene3D G3DSA:2.60.40.1080 316 387 1.0E-9 T 29-03-2018 HVS_RS11045 b3951b8f2f57729a6dd8611be4fe1bf7 446 SUPERFAMILY SSF50939 26 224 1.22E-14 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 HVS_RS11045 b3951b8f2f57729a6dd8611be4fe1bf7 446 SUPERFAMILY SSF117289 159 388 2.35E-6 T 29-03-2018 HVS_RS11045 b3951b8f2f57729a6dd8611be4fe1bf7 446 Gene3D G3DSA:2.130.10.10 151 315 8.4E-12 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS15800 d069a559543b2663b116847127f8fdbd 197 Pfam PF06866 Protein of unknown function (DUF1256) 12 172 1.0E-49 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 HVS_RS15800 d069a559543b2663b116847127f8fdbd 197 SUPERFAMILY SSF53163 7 185 5.1E-46 T 29-03-2018 IPR023430 Peptidase HybD-like domain HVS_RS15800 d069a559543b2663b116847127f8fdbd 197 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 39 174 1.0E-47 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 HVS_RS15800 d069a559543b2663b116847127f8fdbd 197 Gene3D G3DSA:3.40.50.1450 3 193 1.2E-32 T 29-03-2018 IPR023430 Peptidase HybD-like domain HVS_RS14345 196d319287b4aa725d4a92b3fa25e009 235 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS14345 196d319287b4aa725d4a92b3fa25e009 235 Gene3D G3DSA:3.40.50.300 1 235 2.1E-68 T 29-03-2018 HVS_RS14345 196d319287b4aa725d4a92b3fa25e009 235 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 5.2E-87 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 HVS_RS14345 196d319287b4aa725d4a92b3fa25e009 235 Pfam PF00005 ABC transporter 18 165 2.7E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS14345 196d319287b4aa725d4a92b3fa25e009 235 SMART SM00382 27 214 4.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS14345 196d319287b4aa725d4a92b3fa25e009 235 SUPERFAMILY SSF52540 1 228 9.55E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 Gene3D G3DSA:1.10.1330.10 35 102 2.3E-5 T 29-03-2018 HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 SUPERFAMILY SSF56574 112 485 1.44E-103 T 29-03-2018 IPR023796 Serpin domain HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 SMART SM00093 125 486 7.6E-87 T 29-03-2018 IPR023796 Serpin domain HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 ProSitePatterns PS00284 Serpins signature. 459 469 - T 29-03-2018 IPR023795 Serpin, conserved site HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 Pfam PF00404 Dockerin type I repeat 75 95 2.7E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 Gene3D G3DSA:2.30.39.10 288 486 2.3E-55 T 29-03-2018 HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 Pfam PF00079 Serpin (serine protease inhibitor) 119 484 4.0E-102 T 29-03-2018 IPR023796 Serpin domain HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 SUPERFAMILY SSF63446 35 105 7.46E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09435 72eecd9e03934d4f2d82de1a593f4f8a 490 Gene3D G3DSA:3.30.497.10 103 287 2.3E-46 T 29-03-2018 HVS_RS00235 b08c9a4a763f051d94d3840b9be25248 346 SUPERFAMILY SSF52540 168 323 1.04E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00235 b08c9a4a763f051d94d3840b9be25248 346 Pfam PF01695 IstB-like ATP binding protein 178 316 2.9E-15 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS00235 b08c9a4a763f051d94d3840b9be25248 346 Gene3D G3DSA:3.40.50.300 48 321 1.1E-15 T 29-03-2018 HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 Gene3D G3DSA:3.20.20.80 376 710 1.8E-41 T 29-03-2018 HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 Pfam PF00704 Glycosyl hydrolases family 18 475 694 1.1E-19 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 Pfam PF00395 S-layer homology domain 57 96 1.1E-7 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 Pfam PF00395 S-layer homology domain 177 220 5.0E-9 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 Pfam PF00395 S-layer homology domain 116 157 4.2E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 SUPERFAMILY SSF51445 669 705 1.44E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 SUPERFAMILY SSF51445 400 611 1.44E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS11775 f0d863d8b634d53f448093d369a05deb 710 SMART SM00636 379 697 3.9E-6 T 29-03-2018 IPR011583 Chitinase II GO:0008061 HVS_RS06820 627d375cd04f637836ad7b3227150aae 328 SUPERFAMILY SSF55383 52 135 5.36E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06820 627d375cd04f637836ad7b3227150aae 328 Gene3D G3DSA:3.30.457.10 62 122 7.6E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06820 627d375cd04f637836ad7b3227150aae 328 Gene3D G3DSA:3.30.457.10 9 61 6.7E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06820 627d375cd04f637836ad7b3227150aae 328 Gene3D G3DSA:3.30.457.10 123 215 3.5E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06820 627d375cd04f637836ad7b3227150aae 328 Pfam PF07833 Copper amine oxidase N-terminal domain 49 141 9.7E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08175 956264020bfce6d52d830850fb7bd14c 307 Gene3D G3DSA:3.40.50.1010 35 217 0.002 T 29-03-2018 IPR029060 PIN domain-like HVS_RS00255 9257fe8eb0dff02767568bc2a17e3b53 292 Gene3D G3DSA:1.20.58.370 3 42 4.3E-6 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain HVS_RS00255 9257fe8eb0dff02767568bc2a17e3b53 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 282 3.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS00255 9257fe8eb0dff02767568bc2a17e3b53 292 SUPERFAMILY SSF161098 51 281 1.13E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS00255 9257fe8eb0dff02767568bc2a17e3b53 292 Gene3D G3DSA:1.10.3720.10 58 290 4.2E-43 T 29-03-2018 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 Gene3D G3DSA:3.40.50.720 384 482 5.6E-20 T 29-03-2018 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 385 617 7.3E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 Gene3D G3DSA:3.50.50.60 483 614 2.8E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 Gene3D G3DSA:3.20.20.70 2 383 3.3E-120 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 337 6.0E-81 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 SUPERFAMILY SSF51395 3 373 1.28E-112 T 29-03-2018 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 SUPERFAMILY SSF51905 364 641 6.47E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 387 406 7.3E-10 T 29-03-2018 HVS_RS12570 013b9ced145580e24d2682282b668e3b 643 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 507 525 7.3E-10 T 29-03-2018 HVS_RS00565 4f0491ebdcad69b1831d6d5f2e811fe5 79 Gene3D G3DSA:3.10.290.10 1 79 7.1E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS00565 4f0491ebdcad69b1831d6d5f2e811fe5 79 PIRSF PIRSF038881 1 79 2.7E-30 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type HVS_RS00565 4f0491ebdcad69b1831d6d5f2e811fe5 79 Pfam PF01479 S4 domain 1 47 2.7E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS00565 4f0491ebdcad69b1831d6d5f2e811fe5 79 SMART SM00363 1 66 2.3E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS00565 4f0491ebdcad69b1831d6d5f2e811fe5 79 SUPERFAMILY SSF55174 1 76 1.05E-21 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 434 5.7E-9 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 SUPERFAMILY SSF51905 2 319 2.82E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Pfam PF00581 Rhodanese-like domain 467 544 4.9E-11 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Gene3D G3DSA:3.50.50.60 264 329 5.1E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Gene3D G3DSA:3.50.50.60 107 232 1.0E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Gene3D G3DSA:3.50.50.60 11 106 2.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 1.3E-15 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.3E-15 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 287 1.3E-15 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 1.3E-15 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Gene3D G3DSA:3.40.250.10 456 550 2.2E-21 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 SUPERFAMILY SSF52821 453 545 4.85E-24 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 SMART SM00450 453 550 9.7E-21 T 29-03-2018 IPR001763 Rhodanese-like domain HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 7.2E-21 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 7.2E-21 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.2E-21 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 7.2E-21 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 7.2E-21 T 29-03-2018 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Gene3D G3DSA:3.50.50.60 233 263 0.28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 SUPERFAMILY SSF55424 326 448 2.55E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Gene3D G3DSA:3.30.390.30 330 455 2.4E-21 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HVS_RS13815 7b042f5dac1fc1e8921df03879bf0fd4 559 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 310 1.8E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 2.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 2.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 Pfam PF12840 Helix-turn-helix domain 14 67 7.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 SUPERFAMILY SSF46785 4 88 1.03E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 Gene3D G3DSA:1.10.10.10 1 87 1.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14255 dbf2285a91e1ed01be9bff78117644b2 89 SMART SM00418 12 87 1.1E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 SUPERFAMILY SSF56281 517 779 1.15E-49 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 Pfam PF03772 Competence protein 223 487 5.0E-66 T 29-03-2018 IPR004477 ComEC/Rec2-related protein HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 Pfam PF13567 Domain of unknown function (DUF4131) 25 181 1.2E-26 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 147 762 1.5E-99 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 244 418 2.9E-32 T 29-03-2018 IPR004477 ComEC/Rec2-related protein HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 SMART SM00849 529 734 5.0E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 Pfam PF00753 Metallo-beta-lactamase superfamily 526 733 1.4E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS07180 665d27f607c39f4a66e1fbf5a81762ae 780 Gene3D G3DSA:3.60.15.10 518 778 6.8E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 310 1.8E-103 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 Gene3D G3DSA:3.10.28.10 117 231 2.3E-17 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 312 34.472 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 Pfam PF02650 WhiA C-terminal HTH domain 226 309 1.6E-36 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 Gene3D G3DSA:3.10.28.10 13 104 1.7E-11 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 21 107 1.1E-25 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 Pfam PF14527 WhiA LAGLIDADG-like domain 131 223 7.4E-35 T 29-03-2018 HVS_RS12090 ee7b8afb85a8d71ee691c4d26bd8c18a 322 SUPERFAMILY SSF55608 120 227 9.86E-18 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 PIRSF PIRSF000726 1 449 4.5E-85 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 SUPERFAMILY SSF55021 297 364 9.92E-9 T 29-03-2018 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 1.1E-88 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 SUPERFAMILY SSF55021 371 448 4.23E-24 T 29-03-2018 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 Gene3D G3DSA:3.30.70.260 371 449 2.3E-23 T 29-03-2018 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 Gene3D G3DSA:3.30.70.260 282 370 3.7E-18 T 29-03-2018 HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 Pfam PF13840 ACT domain 380 444 3.6E-9 T 29-03-2018 IPR027795 GATS-like ACT domain HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 SUPERFAMILY SSF53633 1 290 3.53E-66 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 Pfam PF00696 Amino acid kinase family 2 276 1.5E-41 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase HVS_RS12190 b2bd286ab911a952cbc04078c9e0f6d7 449 Gene3D G3DSA:3.40.1160.10 1 281 7.9E-57 T 29-03-2018 HVS_RS06335 878bd4a50e2bf36e3a24534654bb1c6e 281 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 2 281 48.741 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HVS_RS06335 878bd4a50e2bf36e3a24534654bb1c6e 281 Pfam PF01680 SOR/SNZ family 8 210 3.1E-107 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HVS_RS06335 878bd4a50e2bf36e3a24534654bb1c6e 281 Gene3D G3DSA:3.20.20.70 16 269 1.2E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS06335 878bd4a50e2bf36e3a24534654bb1c6e 281 PIRSF PIRSF029271 2 281 1.9E-145 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HVS_RS06335 878bd4a50e2bf36e3a24534654bb1c6e 281 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 280 1.8E-145 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 HVS_RS06335 878bd4a50e2bf36e3a24534654bb1c6e 281 SUPERFAMILY SSF51366 16 265 4.71E-63 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Pfam PF00404 Dockerin type I repeat 1080 1100 7.4E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Pfam PF00404 Dockerin type I repeat 1114 1134 1.6E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Gene3D G3DSA:2.115.10.20 158 452 3.8E-39 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Pfam PF04616 Glycosyl hydrolases family 43 194 378 3.6E-13 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Pfam PF04616 Glycosyl hydrolases family 43 729 1048 6.1E-53 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Gene3D G3DSA:1.10.1330.10 1073 1140 9.7E-4 T 29-03-2018 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Gene3D G3DSA:2.115.10.20 723 1066 2.5E-52 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 SUPERFAMILY SSF63446 1076 1138 4.02E-14 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 SUPERFAMILY SSF49899 448 654 1.03E-27 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 1080 1099 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 SUPERFAMILY SSF75005 181 435 4.71E-34 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Pfam PF07532 Bacterial Ig-like domain (group 4) 671 724 1.1E-7 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Gene3D G3DSA:2.60.120.200 453 658 2.6E-31 T 29-03-2018 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 502 653 9.7E-14 T 29-03-2018 HVS_RS07770 8cfd061638d71437c2cfa01137800fd4 1140 SUPERFAMILY SSF75005 729 1058 3.53E-61 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 SMART SM01208 156 234 2.2E-21 T 29-03-2018 IPR011098 G5 domain HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 Pfam PF07501 G5 domain 160 232 1.5E-18 T 29-03-2018 IPR011098 G5 domain HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 Gene3D G3DSA:2.40.40.10 220 352 1.1E-28 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 Gene3D G3DSA:2.20.230.10 157 219 8.9E-16 T 29-03-2018 HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 Pfam PF03990 Domain of unknown function (DUF348) 104 137 2.7E-6 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 Pfam PF03990 Domain of unknown function (DUF348) 43 82 1.4E-11 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 SUPERFAMILY SSF50685 277 332 2.58E-7 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HVS_RS14580 49d255c8e66c82b6029dff844f037d05 353 Pfam PF06725 3D domain 287 351 4.0E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HVS_RS11845 69c8c5a02e294352d50f3be6f945ae40 127 PIRSF PIRSF006113 4 124 4.0E-27 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 HVS_RS11845 69c8c5a02e294352d50f3be6f945ae40 127 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 8 95 2.4E-29 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 HVS_RS11845 69c8c5a02e294352d50f3be6f945ae40 127 SUPERFAMILY SSF55620 5 120 8.34E-36 T 29-03-2018 HVS_RS11845 69c8c5a02e294352d50f3be6f945ae40 127 Gene3D G3DSA:3.30.479.10 4 123 1.0E-37 T 29-03-2018 HVS_RS11845 69c8c5a02e294352d50f3be6f945ae40 127 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 8 122 3.3E-34 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 HVS_RS12750 85f10ecd8353c60e572c234672b7adf6 317 PIRSF PIRSF002849 1 315 4.4E-135 T 29-03-2018 HVS_RS12750 85f10ecd8353c60e572c234672b7adf6 317 Gene3D G3DSA:3.40.50.300 21 187 3.8E-26 T 29-03-2018 HVS_RS12750 85f10ecd8353c60e572c234672b7adf6 317 Gene3D G3DSA:1.10.8.300 201 310 2.0E-32 T 29-03-2018 HVS_RS12750 85f10ecd8353c60e572c234672b7adf6 317 SUPERFAMILY SSF52540 7 284 1.94E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12750 85f10ecd8353c60e572c234672b7adf6 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 2.0E-65 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS03705 d8839ebc64b31be390bb2c53b216e6f8 93 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 7 89 4.1E-13 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HVS_RS03705 d8839ebc64b31be390bb2c53b216e6f8 93 SUPERFAMILY SSF143430 7 85 1.24E-23 T 29-03-2018 HVS_RS03705 d8839ebc64b31be390bb2c53b216e6f8 93 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 6 92 12.9 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HVS_RS03705 d8839ebc64b31be390bb2c53b216e6f8 93 Gene3D G3DSA:3.30.70.240 3 93 1.1E-22 T 29-03-2018 HVS_RS03705 d8839ebc64b31be390bb2c53b216e6f8 93 Pfam PF09827 CRISPR associated protein Cas2 8 73 7.0E-20 T 29-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 HVS_RS04535 a421902e06349c3f30ed1ccf70a49f5b 384 Pfam PF12704 MacB-like periplasmic core domain 23 196 1.1E-8 T 29-03-2018 IPR025857 MacB-like periplasmic core domain HVS_RS04535 a421902e06349c3f30ed1ccf70a49f5b 384 Pfam PF02687 FtsX-like permease family 290 378 4.3E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS09345 da015a254b14255f274436a3d200c7a2 46 TIGRFAM TIGR03973 six_Cys_in_45: six-cysteine peptide SCIFF 2 44 4.5E-25 T 29-03-2018 IPR023975 Six-cysteine peptide SCIFF HVS_RS09345 da015a254b14255f274436a3d200c7a2 46 Pfam PF13165 Six-cysteine peptide SCIFF 2 45 4.9E-25 T 29-03-2018 IPR023975 Six-cysteine peptide SCIFF HVS_RS12795 d91046a5a75efb5bc67c44740df730a4 237 Gene3D G3DSA:3.40.80.10 2 193 1.6E-28 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS12795 d91046a5a75efb5bc67c44740df730a4 237 SMART SM00644 9 167 1.1E-7 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS12795 d91046a5a75efb5bc67c44740df730a4 237 SUPERFAMILY SSF55846 9 184 4.19E-26 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS12795 d91046a5a75efb5bc67c44740df730a4 237 Pfam PF00395 S-layer homology domain 186 227 3.4E-18 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS12795 d91046a5a75efb5bc67c44740df730a4 237 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 22 167 1.9E-15 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 21 424 5.5E-136 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 Pfam PF01979 Amidohydrolase family 51 420 8.1E-36 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 425 44.126 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 Gene3D G3DSA:2.30.40.10 1 68 2.1E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 SUPERFAMILY SSF51338 367 424 2.42E-30 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 SUPERFAMILY SSF51338 2 54 2.42E-30 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 SUPERFAMILY SSF51556 55 367 1.26E-111 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS08905 785ff230e9bc80e13cd05315000b24b4 428 Gene3D G3DSA:3.20.20.140 69 407 6.8E-105 T 29-03-2018 HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 Pfam PF11849 Domain of unknown function (DUF3369) 126 286 3.3E-25 T 29-03-2018 IPR021800 Domain of unknown function DUF3369 HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 Gene3D G3DSA:3.40.50.2300 6 169 4.2E-20 T 29-03-2018 HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 TIGRFAM TIGR00277 HDIG: HDIG domain 326 414 1.9E-8 T 29-03-2018 IPR006675 HDIG domain HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 SUPERFAMILY SSF55781 143 302 5.4E-7 T 29-03-2018 IPR029016 GAF domain-like HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 SUPERFAMILY SSF52172 12 154 1.85E-21 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 SMART SM00448 12 124 5.6E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 Pfam PF01966 HD domain 326 446 7.5E-22 T 29-03-2018 IPR006674 HD domain HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 SMART SM00471 320 455 8.9E-15 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 SUPERFAMILY SSF109604 309 486 2.2E-40 T 29-03-2018 HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 Pfam PF00072 Response regulator receiver domain 14 121 1.1E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS08020 1ab8ad9f0551c5a7ba46a0cf7f1b2ed7 501 Gene3D G3DSA:1.10.3210.10 289 495 9.1E-50 T 29-03-2018 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 PRINTS PR00395 Ribosomal protein S2 signature 158 175 9.5E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 PRINTS PR00395 Ribosomal protein S2 signature 196 210 9.5E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 PRINTS PR00395 Ribosomal protein S2 signature 6 24 9.5E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 PRINTS PR00395 Ribosomal protein S2 signature 87 104 9.5E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 PRINTS PR00395 Ribosomal protein S2 signature 175 186 9.5E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 PRINTS PR00395 Ribosomal protein S2 signature 37 46 9.5E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.8E-111 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.944 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 Pfam PF00318 Ribosomal protein S2 9 224 3.6E-101 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 SUPERFAMILY SSF52313 6 232 2.22E-99 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HVS_RS06340 580676a9d222ea99e1e72095e9f5ec98 273 Gene3D G3DSA:3.40.50.10490 5 267 4.1E-106 T 29-03-2018 HVS_RS00840 e068f10a8e3e66e38048d1f51f3a2334 570 Pfam PF15978 Tn7-like transposition protein D 325 503 1.1E-34 T 29-03-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl HVS_RS00840 e068f10a8e3e66e38048d1f51f3a2334 570 Pfam PF15978 Tn7-like transposition protein D 202 309 3.6E-24 T 29-03-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl HVS_RS00840 e068f10a8e3e66e38048d1f51f3a2334 570 Pfam PF06527 TniQ 4 160 1.9E-18 T 29-03-2018 IPR009492 TniQ HVS_RS00840 e068f10a8e3e66e38048d1f51f3a2334 570 Gene3D G3DSA:1.10.10.60 322 396 1.0E-5 T 29-03-2018 HVS_RS03630 e9b026dcf44f2c6e91d8f26ba911e244 282 SUPERFAMILY SSF81336 120 256 3.53E-10 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03630 e9b026dcf44f2c6e91d8f26ba911e244 282 Pfam PF00119 ATP synthase A chain 67 255 7.0E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03630 e9b026dcf44f2c6e91d8f26ba911e244 282 Gene3D G3DSA:1.20.120.220 6 263 2.1E-8 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS15640 5a7ec93fcf4e46871031666e8e98ca9a 51 SUPERFAMILY SSF63446 23 49 1.11E-7 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS15640 5a7ec93fcf4e46871031666e8e98ca9a 51 Pfam PF00404 Dockerin type I repeat 28 47 5.9E-8 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS15640 5a7ec93fcf4e46871031666e8e98ca9a 51 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 28 47 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS14825 1020487314a5a639514d38649c5a7c95 641 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 21 123 6.6E-23 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 HVS_RS14825 1020487314a5a639514d38649c5a7c95 641 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 347 628 1.0E-45 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 HVS_RS06000 1020487314a5a639514d38649c5a7c95 641 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 21 123 6.6E-23 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 HVS_RS06000 1020487314a5a639514d38649c5a7c95 641 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 347 628 1.0E-45 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 HVS_RS08235 b3e9524eedbb2e056225c6342361c22e 264 Hamap MF_01805 Segregation and condensation protein A [scpA]. 9 248 24.355 T 29-03-2018 IPR003768 Segregation and condensation protein A HVS_RS08235 b3e9524eedbb2e056225c6342361c22e 264 Pfam PF02616 Segregation and condensation protein ScpA 26 244 2.7E-34 T 29-03-2018 IPR003768 Segregation and condensation protein A HVS_RS08235 b3e9524eedbb2e056225c6342361c22e 264 Gene3D G3DSA:2.70.9.10 8 175 0.094 T 29-03-2018 IPR016111 Hexon coat protein, subdomain 4 GO:0005198|GO:0019028 HVS_RS08235 b3e9524eedbb2e056225c6342361c22e 264 Gene3D G3DSA:1.10.10.580 176 245 4.2E-9 T 29-03-2018 HVS_RS09655 e40eb2825fd7e10594bc93cb1a9c8697 322 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 10 320 4.0E-75 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09655 e40eb2825fd7e10594bc93cb1a9c8697 322 Pfam PF00849 RNA pseudouridylate synthase 88 238 1.5E-26 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09655 e40eb2825fd7e10594bc93cb1a9c8697 322 SUPERFAMILY SSF55120 71 320 1.42E-66 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS09655 e40eb2825fd7e10594bc93cb1a9c8697 322 Gene3D G3DSA:3.10.290.10 2 70 7.5E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS09655 e40eb2825fd7e10594bc93cb1a9c8697 322 Gene3D G3DSA:3.30.2350.10 78 322 6.3E-64 T 29-03-2018 HVS_RS10070 144036556a6777c49d355c9d88c8c418 195 SUPERFAMILY SSF53098 1 182 4.0E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS10070 144036556a6777c49d355c9d88c8c418 195 Gene3D G3DSA:3.30.420.10 1 189 3.6E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS10070 144036556a6777c49d355c9d88c8c418 195 SMART SM00479 2 178 1.3E-13 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HVS_RS10070 144036556a6777c49d355c9d88c8c418 195 Pfam PF00929 Exonuclease 18 169 6.8E-17 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 36 511 9.7E-99 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 Pfam PF13091 PLD-like domain 353 476 2.9E-22 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 Pfam PF13091 PLD-like domain 161 272 2.8E-13 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 Gene3D G3DSA:3.30.870.10 109 308 1.6E-29 T 29-03-2018 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 SUPERFAMILY SSF56024 325 492 7.63E-37 T 29-03-2018 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 SMART SM00155 424 451 7.6E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 SMART SM00155 244 271 1.5E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 Gene3D G3DSA:3.30.870.10 347 502 3.3E-27 T 29-03-2018 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 SUPERFAMILY SSF56024 137 318 7.85E-40 T 29-03-2018 HVS_RS09455 f942ab8bef58536e9fec5f22c8e2cb6c 511 Pfam PF13396 Phospholipase_D-nuclease N-terminal 46 87 3.0E-12 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal HVS_RS06060 7fa38cd19b86ffb9d736085ed272f1d3 351 Gene3D G3DSA:3.40.718.10 213 351 7.0E-48 T 29-03-2018 HVS_RS06060 7fa38cd19b86ffb9d736085ed272f1d3 351 Gene3D G3DSA:3.40.718.10 1 212 3.6E-69 T 29-03-2018 HVS_RS06060 7fa38cd19b86ffb9d736085ed272f1d3 351 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HVS_RS06060 7fa38cd19b86ffb9d736085ed272f1d3 351 SMART SM01329 5 347 1.0E-171 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS06060 7fa38cd19b86ffb9d736085ed272f1d3 351 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 347 6.1E-97 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS06060 7fa38cd19b86ffb9d736085ed272f1d3 351 SUPERFAMILY SSF53659 1 351 1.65E-118 T 29-03-2018 HVS_RS14765 7fa38cd19b86ffb9d736085ed272f1d3 351 Gene3D G3DSA:3.40.718.10 213 351 7.0E-48 T 29-03-2018 HVS_RS14765 7fa38cd19b86ffb9d736085ed272f1d3 351 Gene3D G3DSA:3.40.718.10 1 212 3.6E-69 T 29-03-2018 HVS_RS14765 7fa38cd19b86ffb9d736085ed272f1d3 351 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 HVS_RS14765 7fa38cd19b86ffb9d736085ed272f1d3 351 SMART SM01329 5 347 1.0E-171 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS14765 7fa38cd19b86ffb9d736085ed272f1d3 351 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 347 6.1E-97 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 HVS_RS14765 7fa38cd19b86ffb9d736085ed272f1d3 351 SUPERFAMILY SSF53659 1 351 1.65E-118 T 29-03-2018 HVS_RS06265 1e497f98e09ba2347cffa5f984a75b87 112 Gene3D G3DSA:3.30.460.10 1 112 4.4E-35 T 29-03-2018 HVS_RS06265 1e497f98e09ba2347cffa5f984a75b87 112 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 1.0E-35 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HVS_RS06265 1e497f98e09ba2347cffa5f984a75b87 112 SUPERFAMILY SSF81301 4 108 9.81E-38 T 29-03-2018 HVS_RS06265 1e497f98e09ba2347cffa5f984a75b87 112 Pfam PF02410 Ribosomal silencing factor during starvation 9 104 3.7E-28 T 29-03-2018 HVS_RS06265 1e497f98e09ba2347cffa5f984a75b87 112 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.655 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HVS_RS03405 fc2c9fc55c457b60932ef3e517575f70 102 Pfam PF06013 Proteins of 100 residues with WXG 5 89 1.4E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03405 fc2c9fc55c457b60932ef3e517575f70 102 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 90 7.1E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03405 fc2c9fc55c457b60932ef3e517575f70 102 Gene3D G3DSA:1.10.287.1060 1 97 4.4E-16 T 29-03-2018 HVS_RS03405 fc2c9fc55c457b60932ef3e517575f70 102 SUPERFAMILY SSF140453 5 93 7.98E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03510 fc2c9fc55c457b60932ef3e517575f70 102 Pfam PF06013 Proteins of 100 residues with WXG 5 89 1.4E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03510 fc2c9fc55c457b60932ef3e517575f70 102 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 90 7.1E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03510 fc2c9fc55c457b60932ef3e517575f70 102 Gene3D G3DSA:1.10.287.1060 1 97 4.4E-16 T 29-03-2018 HVS_RS03510 fc2c9fc55c457b60932ef3e517575f70 102 SUPERFAMILY SSF140453 5 93 7.98E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03925 651c19afd1a24dcf45cba2c746cf629e 121 Gene3D G3DSA:1.10.1220.10 17 68 8.9E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 HVS_RS14985 263120c9a33ddf5f6fe7f0d83d19f12e 279 Pfam PF00005 ABC transporter 23 169 2.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS14985 263120c9a33ddf5f6fe7f0d83d19f12e 279 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 3 271 4.4E-112 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 HVS_RS14985 263120c9a33ddf5f6fe7f0d83d19f12e 279 SUPERFAMILY SSF52540 2 231 4.21E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14985 263120c9a33ddf5f6fe7f0d83d19f12e 279 Gene3D G3DSA:3.40.50.300 1 240 2.4E-67 T 29-03-2018 HVS_RS14985 263120c9a33ddf5f6fe7f0d83d19f12e 279 SMART SM00382 31 217 4.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS14985 263120c9a33ddf5f6fe7f0d83d19f12e 279 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS10705 55586f214e3878384682e423f5b324eb 864 Pfam PF02018 Carbohydrate binding domain 43 173 3.5E-8 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS10705 55586f214e3878384682e423f5b324eb 864 Gene3D G3DSA:3.40.50.410 245 741 9.0E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10705 55586f214e3878384682e423f5b324eb 864 SUPERFAMILY SSF49785 41 195 1.3E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS10705 55586f214e3878384682e423f5b324eb 864 Gene3D G3DSA:2.60.120.260 33 205 3.8E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS10705 55586f214e3878384682e423f5b324eb 864 SUPERFAMILY SSF53300 661 734 2.23E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10705 55586f214e3878384682e423f5b324eb 864 SUPERFAMILY SSF53300 528 631 2.23E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 SUPERFAMILY SSF89919 3 110 1.44E-34 T 29-03-2018 IPR023799 Ribosome-binding factor A domain HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 2.6E-36 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 6 94 1.0E-31 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 114 21.83 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 Pfam PF02033 Ribosome-binding factor A 3 107 1.2E-34 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 HVS_RS10515 662e8ca74c4f80919fe3e36ad55c98bc 117 Gene3D G3DSA:3.30.300.20 1 114 1.3E-38 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS09840 0575d21543c7fa7cc38c004d7e72fb46 383 SUPERFAMILY SSF53756 3 380 3.03E-99 T 29-03-2018 HVS_RS09840 0575d21543c7fa7cc38c004d7e72fb46 383 Gene3D G3DSA:3.40.50.2000 4 203 3.1E-53 T 29-03-2018 HVS_RS09840 0575d21543c7fa7cc38c004d7e72fb46 383 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 5 366 1.6E-145 T 29-03-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001 HVS_RS09840 0575d21543c7fa7cc38c004d7e72fb46 383 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 367 3.5E-93 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 HVS_RS09840 0575d21543c7fa7cc38c004d7e72fb46 383 Gene3D G3DSA:3.40.50.2000 204 347 1.0E-28 T 29-03-2018 HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 SUPERFAMILY SSF52540 278 458 3.39E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 Pfam PF13807 G-rich domain on putative tyrosine kinase 133 195 4.3E-12 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 Gene3D G3DSA:3.30.1890.10 144 172 0.11 T 29-03-2018 HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 Gene3D G3DSA:3.30.1890.10 41 143 2.9E-14 T 29-03-2018 HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 259 461 1.0E-56 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 Gene3D G3DSA:3.40.50.300 242 465 2.6E-38 T 29-03-2018 HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 Pfam PF13614 AAA domain 287 424 2.9E-15 T 29-03-2018 IPR025669 AAA domain HVS_RS06130 679290ff84a972afce9b90d8903d3d6f 468 Pfam PF02706 Chain length determinant protein 7 96 3.7E-13 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 HVS_RS00320 9891b5b694cc17546c481184bde643f9 357 Gene3D G3DSA:2.60.40.1120 1 73 0.0018 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Gene3D G3DSA:1.20.272.10 245 339 1.7E-35 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 49 68 8.7E-8 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 357 376 8.7E-8 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 45 155 1.8E-16 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Gene3D G3DSA:3.40.50.300 2 146 1.8E-28 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Gene3D G3DSA:1.10.8.60 147 236 7.8E-20 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 SUPERFAMILY SSF52540 5 233 7.59E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Pfam PF12002 MgsA AAA+ ATPase C terminal 261 425 3.8E-73 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 SMART SM00382 41 158 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Gene3D G3DSA:1.10.3710.10 342 432 9.1E-37 T 29-03-2018 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 SUPERFAMILY SSF48019 246 428 3.74E-77 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 HVS_RS09865 8f1622e93f6d69456bad4afd991c44ab 432 Pfam PF16193 AAA C-terminal domain 182 260 2.6E-25 T 29-03-2018 IPR032423 AAA C-terminal domain HVS_RS12095 224d048e2e4b7da18a8a5461ba997d1c 653 TIGRFAM TIGR01561 gde_arch: putative glycogen debranching enzyme, archaeal type 18 585 9.2E-161 T 29-03-2018 IPR006451 Glycogen debranching enzyme, archaeal type HVS_RS12095 224d048e2e4b7da18a8a5461ba997d1c 653 Pfam PF12439 Glycogen debranching enzyme N terminal 17 233 2.0E-75 T 29-03-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal HVS_RS12095 224d048e2e4b7da18a8a5461ba997d1c 653 SUPERFAMILY SSF48208 193 651 1.16E-93 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS12095 224d048e2e4b7da18a8a5461ba997d1c 653 Gene3D G3DSA:1.50.10.10 417 648 3.2E-45 T 29-03-2018 HVS_RS12095 224d048e2e4b7da18a8a5461ba997d1c 653 Pfam PF06202 Amylo-alpha-1,6-glucosidase 281 645 5.7E-139 T 29-03-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 HVS_RS12095 224d048e2e4b7da18a8a5461ba997d1c 653 Gene3D G3DSA:1.50.10.10 142 416 6.0E-19 T 29-03-2018 HVS_RS13610 f6c8eb9f7b9c242d5b26f3b4ff7375a2 243 SUPERFAMILY SSF46955 16 89 1.83E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain HVS_RS13610 f6c8eb9f7b9c242d5b26f3b4ff7375a2 243 SMART SM00422 5 63 0.0037 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS13610 f6c8eb9f7b9c242d5b26f3b4ff7375a2 243 Gene3D G3DSA:1.10.1660.10 14 124 1.6E-12 T 29-03-2018 HVS_RS13610 f6c8eb9f7b9c242d5b26f3b4ff7375a2 243 Pfam PF13411 MerR HTH family regulatory protein 16 61 3.0E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS01820 5ba091fcd348843fe5eb160463b7b16e 272 Pfam PF00578 AhpC/TSA family 136 251 1.1E-27 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 HVS_RS01820 5ba091fcd348843fe5eb160463b7b16e 272 Gene3D G3DSA:3.40.30.10 48 272 5.7E-38 T 29-03-2018 HVS_RS01820 5ba091fcd348843fe5eb160463b7b16e 272 SUPERFAMILY SSF52833 136 271 9.42E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS00295 01acdc58d8be85de00581d68cc0cddfc 355 Gene3D G3DSA:1.10.1330.10 284 355 7.0E-7 T 29-03-2018 HVS_RS00295 01acdc58d8be85de00581d68cc0cddfc 355 SUPERFAMILY SSF63446 285 355 3.14E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS00295 01acdc58d8be85de00581d68cc0cddfc 355 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 40 277 1.4E-39 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain HVS_RS00295 01acdc58d8be85de00581d68cc0cddfc 355 SUPERFAMILY SSF52266 41 284 5.23E-46 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS00295 01acdc58d8be85de00581d68cc0cddfc 355 Gene3D G3DSA:3.40.50.1110 38 279 4.5E-43 T 29-03-2018 HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 Gene3D G3DSA:3.40.50.720 122 291 2.3E-36 T 29-03-2018 HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 12 285 2.2E-80 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 SUPERFAMILY SSF53223 7 110 3.34E-33 T 29-03-2018 HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 11 293 35.212 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 SUPERFAMILY SSF51735 111 284 1.81E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 125 206 1.1E-11 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 16 98 3.3E-27 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 HVS_RS07700 be41da6dfe56194d367776fd5ae482fd 293 Gene3D G3DSA:3.40.50.10860 2 121 7.4E-42 T 29-03-2018 HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 Pfam PF07883 Cupin domain 112 182 6.4E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 Gene3D G3DSA:2.60.120.10 70 184 1.1E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 SUPERFAMILY SSF51182 74 183 1.47E-28 T 29-03-2018 IPR011051 RmlC-like cupin domain HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 SUPERFAMILY SSF47413 4 72 4.35E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 Pfam PF12844 Helix-turn-helix domain 10 70 1.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 SMART SM00530 11 66 5.2E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS04895 8cb2c574084c0b8244cce0f87901a495 184 Gene3D G3DSA:1.10.260.40 2 69 4.4E-13 T 29-03-2018 HVS_RS04980 d02d1b508a9e4450397eea7ead29fd6e 293 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 17 222 1.2E-27 T 29-03-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR HVS_RS04980 d02d1b508a9e4450397eea7ead29fd6e 293 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 13 271 3.1E-86 T 29-03-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap HVS_RS04980 d02d1b508a9e4450397eea7ead29fd6e 293 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 8 227 5.7E-57 T 29-03-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR HVS_RS11415 38588bb47e85dfde839700f0794f5154 188 SUPERFAMILY SSF82171 86 177 2.49E-7 T 29-03-2018 HVS_RS11415 38588bb47e85dfde839700f0794f5154 188 Gene3D G3DSA:2.130.10.150 12 187 4.1E-6 T 29-03-2018 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 SMART SM00883 2 93 2.4E-50 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 SUPERFAMILY SSF50129 1 94 1.18E-33 T 29-03-2018 IPR011032 GroES-like HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 Gene3D G3DSA:2.30.33.40 1 94 2.4E-37 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 2.0E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 Hamap MF_00580 10 kDa chaperonin [groS]. 2 94 25.426 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 PRINTS PR00297 10kDa chaperonin signature 3 18 9.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 PRINTS PR00297 10kDa chaperonin signature 59 71 9.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 PRINTS PR00297 10kDa chaperonin signature 80 93 9.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS15230 8ebb9799345aec1889251cefdd17d22d 94 PRINTS PR00297 10kDa chaperonin signature 25 46 9.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 168 3.6E-57 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 Gene3D G3DSA:3.40.50.970 1 192 3.4E-63 T 29-03-2018 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 Gene3D G3DSA:3.40.50.1220 193 344 2.8E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 326 1.2E-46 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 SUPERFAMILY SSF52518 1 182 4.42E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 554 3.8E-239 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 530 6.8E-51 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 Gene3D G3DSA:3.40.50.970 345 542 3.0E-50 T 29-03-2018 HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 SUPERFAMILY SSF52467 186 352 1.19E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS12995 72d6adfe38fd5ed6dd23a3c7740f7aac 555 SUPERFAMILY SSF52518 359 553 7.86E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS01570 2562d20cad23c60bb548ff504456e829 547 Pfam PF03354 Phage Terminase 64 530 4.5E-74 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type HVS_RS03270 6c8be4d93291a687b59c10b5316c7ea7 172 Pfam PF04138 GtrA-like protein 30 170 5.7E-16 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Pfam PF05991 YacP-like NYN domain 716 878 2.0E-50 T 29-03-2018 IPR010298 Protein of unknown function DUF901 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SUPERFAMILY SSF54980 322 397 1.91E-12 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Pfam PF03764 Elongation factor G, domain IV 395 509 3.8E-18 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Gene3D G3DSA:3.30.70.240 526 600 3.6E-12 T 29-03-2018 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SUPERFAMILY SSF50447 210 314 2.69E-15 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Gene3D G3DSA:3.30.230.10 409 525 7.5E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Pfam PF00679 Elongation factor G C-terminus 512 594 1.8E-16 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 145 7.1E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Pfam PF00009 Elongation factor Tu GTP binding domain 5 222 2.7E-54 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 PRINTS PR00315 GTP-binding elongation factor signature 5 18 3.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 PRINTS PR00315 GTP-binding elongation factor signature 51 59 3.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 PRINTS PR00315 GTP-binding elongation factor signature 71 81 3.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 PRINTS PR00315 GTP-binding elongation factor signature 123 132 3.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 PRINTS PR00315 GTP-binding elongation factor signature 87 98 3.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Gene3D G3DSA:2.40.30.10 236 318 4.2E-17 T 29-03-2018 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SUPERFAMILY SSF52540 6 222 4.24E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SUPERFAMILY SSF54980 512 594 2.4E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SUPERFAMILY SSF54211 396 510 4.17E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Gene3D G3DSA:3.40.50.300 1 235 6.8E-40 T 29-03-2018 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 Gene3D G3DSA:3.30.70.870 319 408 3.9E-14 T 29-03-2018 HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SMART SM00838 512 598 0.0055 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like HVS_RS11340 46dc4d17e159035b949550aa5bb1275c 882 SMART SM00889 396 510 4.2E-28 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HVS_RS14555 272e5268709544465224b6a9169cfe77 134 Gene3D G3DSA:1.20.5.340 67 134 2.0E-5 T 29-03-2018 HVS_RS14555 272e5268709544465224b6a9169cfe77 134 SUPERFAMILY SSF102829 6 92 1.06E-17 T 29-03-2018 IPR007838 Cell division protein ZapA-like HVS_RS14555 272e5268709544465224b6a9169cfe77 134 Pfam PF05164 Cell division protein ZapA 7 92 1.5E-20 T 29-03-2018 IPR007838 Cell division protein ZapA-like HVS_RS01635 c40bf87792f01d4efb5b98c8bba41dab 1121 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 9 52 6.8E-6 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal HVS_RS01635 c40bf87792f01d4efb5b98c8bba41dab 1121 Gene3D G3DSA:1.20.120.20 753 1016 6.9E-6 T 29-03-2018 HVS_RS01635 c40bf87792f01d4efb5b98c8bba41dab 1121 Gene3D G3DSA:1.20.120.330 274 460 0.0022 T 29-03-2018 HVS_RS01635 c40bf87792f01d4efb5b98c8bba41dab 1121 Gene3D G3DSA:1.20.5.170 170 273 2.5E-4 T 29-03-2018 HVS_RS10380 056c72771e1dcc60bf7394fcf7866cb2 235 Pfam PF02361 Cobalt transport protein 15 203 1.9E-17 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component HVS_RS04140 a0f877c7eeee73771b0067548bcc6569 288 SUPERFAMILY SSF51219 12 210 6.28E-35 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain HVS_RS04140 a0f877c7eeee73771b0067548bcc6569 288 Gene3D G3DSA:3.60.160.10 7 213 7.8E-37 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 HVS_RS04140 a0f877c7eeee73771b0067548bcc6569 288 Pfam PF01987 Mitochondrial biogenesis AIM24 19 205 5.4E-22 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 4.0E-110 T 29-03-2018 HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 SUPERFAMILY SSF52317 17 297 1.15E-112 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 Gene3D G3DSA:3.40.50.880 34 301 1.4E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 PIRSF PIRSF000450 1 307 5.1E-157 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 Pfam PF04204 Homoserine O-succinyltransferase 2 299 4.9E-146 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 57.129 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 HVS_RS05890 ff1fc2652e68dc1557ac39a7035ebec1 307 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 2.1E-146 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 SUPERFAMILY SSF55781 72 341 9.42E-56 T 29-03-2018 IPR029016 GAF domain-like HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 SUPERFAMILY SSF46785 3 85 4.95E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 Pfam PF01628 HrcA protein C terminal domain 106 325 5.3E-58 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 PIRSF PIRSF005485 1 344 1.3E-104 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 337 1.5E-103 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 Gene3D G3DSA:3.30.450.40 185 344 6.9E-38 T 29-03-2018 IPR029016 GAF domain-like HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 333 29.884 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HVS_RS11115 f264218b3c8db02c82d6e14b6075e586 351 Gene3D G3DSA:1.10.10.10 1 86 3.7E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 Gene3D G3DSA:3.40.50.800 336 418 6.1E-4 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 13 325 6.8E-106 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 Pfam PF13393 Histidyl-tRNA synthetase 11 319 1.3E-79 T 29-03-2018 HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 SUPERFAMILY SSF55681 7 328 3.19E-74 T 29-03-2018 HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 Gene3D G3DSA:3.30.930.10 1 334 3.2E-74 T 29-03-2018 HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 378 32.9 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 HVS_RS15275 d828ba8ba4a43e297da8fb0bb30860e7 418 PIRSF PIRSF001549 2 418 2.2E-91 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 HVS_RS06475 1f286b480a8a7f96495f7292393a1e87 288 Gene3D G3DSA:3.20.20.70 46 285 7.2E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS06475 1f286b480a8a7f96495f7292393a1e87 288 SUPERFAMILY SSF102114 53 282 2.88E-30 T 29-03-2018 HVS_RS06475 1f286b480a8a7f96495f7292393a1e87 288 Pfam PF04055 Radical SAM superfamily 82 227 1.8E-22 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS06475 1f286b480a8a7f96495f7292393a1e87 288 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 9 288 5.7E-82 T 29-03-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme HVS_RS06475 1f286b480a8a7f96495f7292393a1e87 288 PIRSF PIRSF004869 2 288 1.4E-82 T 29-03-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 1.1E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 Gene3D G3DSA:1.10.287.180 5 77 6.4E-30 T 29-03-2018 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 156 9.8E-57 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 SUPERFAMILY SSF46557 6 80 7.32E-26 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 Gene3D G3DSA:3.10.50.30 78 158 2.6E-26 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 SUPERFAMILY SSF54534 82 156 1.57E-21 T 29-03-2018 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 4.1E-30 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 31.671 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 HVS_RS15195 557b66a11b8afcebd4457c0ab17a63b1 158 PIRSF PIRSF006092 1 158 1.4E-51 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 HVS_RS02180 3cde7e1cad9423b3e98a02dfe72b9b06 283 PIRSF PIRSF006648 2 280 5.7E-23 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HVS_RS02180 3cde7e1cad9423b3e98a02dfe72b9b06 283 Pfam PF01061 ABC-2 type transporter 2 223 3.8E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 SUPERFAMILY SSF53067 139 313 9.84E-18 T 29-03-2018 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 Pfam PF01966 HD domain 345 457 1.1E-8 T 29-03-2018 IPR006674 HD domain HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 Pfam PF02541 Ppx/GppA phosphatase family 50 311 4.6E-28 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 Gene3D G3DSA:3.30.420.40 1 130 1.5E-32 T 29-03-2018 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 Gene3D G3DSA:3.30.420.150 135 316 1.6E-22 T 29-03-2018 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 SUPERFAMILY SSF109604 328 512 1.84E-36 T 29-03-2018 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 Gene3D G3DSA:1.10.3210.10 327 504 5.3E-8 T 29-03-2018 HVS_RS05125 3af0c96d9a0a5f759025e8d9dfffd252 515 SUPERFAMILY SSF53067 9 130 5.18E-27 T 29-03-2018 HVS_RS02330 2cb9e09b2291c824a4e216d6c36db0df 349 SUPERFAMILY SSF74650 12 348 4.9E-118 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 HVS_RS02330 2cb9e09b2291c824a4e216d6c36db0df 349 Pfam PF01263 Aldose 1-epimerase 18 347 2.8E-96 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 HVS_RS02330 2cb9e09b2291c824a4e216d6c36db0df 349 Gene3D G3DSA:2.70.98.10 6 349 1.6E-119 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 HVS_RS02330 2cb9e09b2291c824a4e216d6c36db0df 349 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 176 185 - T 29-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 HVS_RS02330 2cb9e09b2291c824a4e216d6c36db0df 349 PIRSF PIRSF005096 1 349 7.9E-135 T 29-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 HVS_RS08485 49e8e3139a507430fddb4452cc743000 95 SUPERFAMILY SSF141523 2 94 3.79E-20 T 29-03-2018 HVS_RS08485 49e8e3139a507430fddb4452cc743000 95 Gene3D G3DSA:2.40.440.10 1 95 2.5E-20 T 29-03-2018 HVS_RS08485 49e8e3139a507430fddb4452cc743000 95 Pfam PF03734 L,D-transpeptidase catalytic domain 1 94 3.6E-13 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 HVS_RS06640 37efdaa6bdd42ae5b42c41341ee15b30 167 SUPERFAMILY SSF50118 16 135 7.41E-11 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS06640 37efdaa6bdd42ae5b42c41341ee15b30 167 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 18 130 1.4E-10 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HVS_RS06640 37efdaa6bdd42ae5b42c41341ee15b30 167 Gene3D G3DSA:2.30.30.110 13 158 1.7E-15 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 SUPERFAMILY SSF116726 141 216 4.19E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 Pfam PF02080 TrkA-C domain 151 216 2.7E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 Gene3D G3DSA:3.40.50.720 2 118 2.7E-24 T 29-03-2018 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 Gene3D G3DSA:3.30.70.1450 136 221 1.4E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 Pfam PF02254 TrkA-N domain 3 118 1.9E-29 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.6E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.6E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.6E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HVS_RS05505 424b050482afd8c248f192c8cc69410d 222 SUPERFAMILY SSF51735 1 145 6.74E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS08920 29e0e1c1638ab11cc130d0c362e748f5 184 SUPERFAMILY SSF53271 6 168 9.44E-44 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS08920 29e0e1c1638ab11cc130d0c362e748f5 184 Pfam PF00156 Phosphoribosyl transferase domain 13 162 4.1E-23 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HVS_RS08920 29e0e1c1638ab11cc130d0c362e748f5 184 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 37.171 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HVS_RS08920 29e0e1c1638ab11cc130d0c362e748f5 184 Gene3D G3DSA:3.40.50.2020 1 180 1.4E-38 T 29-03-2018 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 3.6E-21 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 128 26.19 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 Gene3D G3DSA:3.30.1390.10 58 128 6.5E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 9.1E-50 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 Gene3D G3DSA:1.20.5.710 3 57 3.1E-20 T 29-03-2018 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 SUPERFAMILY SSF48300 5 64 2.75E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 128 1.0E-22 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 SUPERFAMILY SSF54736 57 128 1.66E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HVS_RS12960 cd4351a6654329f235f2df99fe9c2766 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 128 4.5E-31 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 SMART SM00100 12 133 4.2E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 SUPERFAMILY SSF46785 155 218 6.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 Gene3D G3DSA:1.10.10.10 154 220 9.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 SUPERFAMILY SSF51206 3 147 5.63E-30 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 Gene3D G3DSA:2.60.120.10 1 153 1.4E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 Pfam PF13545 Crp-like helix-turn-helix domain 158 217 4.8E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HVS_RS13910 880f3de76115a8754d864e33a94829c2 220 Pfam PF00027 Cyclic nucleotide-binding domain 34 119 3.0E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain HVS_RS10055 123ff36c02ba9c5d6a82e27bbb89d506 226 Pfam PF12673 Domain of unknown function (DUF3794) 94 175 5.8E-10 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 HVS_RS11380 6c7aa0a48f6c861dc35ff000b3dc0950 103 Gene3D G3DSA:3.30.110.70 1 102 4.5E-30 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 HVS_RS11380 6c7aa0a48f6c861dc35ff000b3dc0950 103 Pfam PF01906 Putative heavy-metal-binding 1 101 5.4E-35 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 HVS_RS11380 6c7aa0a48f6c861dc35ff000b3dc0950 103 SUPERFAMILY SSF117782 1 103 4.45E-33 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 HVS_RS11380 6c7aa0a48f6c861dc35ff000b3dc0950 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 102 23.168 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 HVS_RS02025 ce9ce91f6ec8a96e0d5a97e600f85634 746 SUPERFAMILY SSF52540 476 635 2.12E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02025 ce9ce91f6ec8a96e0d5a97e600f85634 746 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 398 704 4.7E-87 T 29-03-2018 IPR006500 DNA primase, phage/plasmid HVS_RS02025 ce9ce91f6ec8a96e0d5a97e600f85634 746 Pfam PF08706 D5 N terminal like 297 447 5.3E-32 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS02025 ce9ce91f6ec8a96e0d5a97e600f85634 746 Gene3D G3DSA:3.40.50.300 416 638 2.9E-18 T 29-03-2018 HVS_RS02025 ce9ce91f6ec8a96e0d5a97e600f85634 746 SMART SM00885 297 449 4.4E-42 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 Pfam PF00753 Metallo-beta-lactamase superfamily 34 175 9.6E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 Gene3D G3DSA:3.60.15.10 1 244 4.7E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 Gene3D G3DSA:3.40.50.360 252 392 2.9E-19 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 SUPERFAMILY SSF52218 250 392 9.72E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 Pfam PF00258 Flavodoxin 254 383 1.9E-9 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 SMART SM00849 33 224 1.8E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 SUPERFAMILY SSF56281 2 243 2.88E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS03205 b049a55beedcb86f27b906174af2df9c 393 PIRSF PIRSF005243 1 393 6.5E-149 T 29-03-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 HVS_RS01755 d4fda71725b939f20b16df04309eb734 990 Pfam PF00395 S-layer homology domain 48 91 1.7E-9 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01755 d4fda71725b939f20b16df04309eb734 990 Pfam PF00395 S-layer homology domain 197 240 3.9E-9 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS10610 fea8a88b5bee1f41da70f16cbf4f41a1 468 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 150 346 9.9E-27 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT HVS_RS10610 fea8a88b5bee1f41da70f16cbf4f41a1 468 PIRSF PIRSF500217 1 468 1.2E-136 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 HVS_RS10610 fea8a88b5bee1f41da70f16cbf4f41a1 468 PIRSF PIRSF016636 1 468 1.2E-133 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB HVS_RS09950 41086abd64be224d1c121c4b6127fd71 71 Pfam PF14035 YlzJ-like protein 3 69 1.0E-19 T 29-03-2018 IPR025619 YlzJ-like protein HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 Gene3D G3DSA:2.30.30.60 120 169 8.9E-18 T 29-03-2018 HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 SUPERFAMILY SSF82861 20 103 1.15E-15 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 SUPERFAMILY SSF50182 105 170 4.58E-19 T 29-03-2018 IPR010920 LSM domain HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 SUPERFAMILY SSF82689 173 270 6.15E-29 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 Pfam PF00924 Mechanosensitive ion channel 64 258 2.0E-52 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 Gene3D G3DSA:3.30.70.100 170 264 7.1E-26 T 29-03-2018 HVS_RS06925 46ab25a1c9a5e557222707f0a8c97398 274 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 134 168 - T 29-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 HVS_RS10710 a762219b2617800565f8724c46638497 138 Gene3D G3DSA:3.10.129.10 3 138 2.8E-32 T 29-03-2018 HVS_RS10710 a762219b2617800565f8724c46638497 138 Pfam PF03061 Thioesterase superfamily 18 101 8.7E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 HVS_RS10710 a762219b2617800565f8724c46638497 138 PIRSF PIRSF003230 2 137 2.5E-39 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HVS_RS10710 a762219b2617800565f8724c46638497 138 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 10 122 4.0E-26 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HVS_RS10710 a762219b2617800565f8724c46638497 138 SUPERFAMILY SSF54637 4 130 1.15E-38 T 29-03-2018 IPR029069 HotDog domain HVS_RS02275 cce03aa02ae2fe8ab1603ecb6171a7b9 415 Gene3D G3DSA:3.20.20.140 232 414 5.9E-25 T 29-03-2018 HVS_RS02275 cce03aa02ae2fe8ab1603ecb6171a7b9 415 SUPERFAMILY SSF51556 5 413 2.01E-109 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS02275 cce03aa02ae2fe8ab1603ecb6171a7b9 415 Gene3D G3DSA:3.20.20.140 107 226 3.0E-11 T 29-03-2018 HVS_RS02275 cce03aa02ae2fe8ab1603ecb6171a7b9 415 Gene3D G3DSA:1.10.2020.10 40 106 3.1E-33 T 29-03-2018 HVS_RS08480 2b4cac10bb53c4b14ba02758659977c1 564 SUPERFAMILY SSF63446 498 562 1.86E-14 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS08480 2b4cac10bb53c4b14ba02758659977c1 564 Pfam PF12708 Pectate lyase superfamily protein 50 125 1.8E-18 T 29-03-2018 IPR024535 Pectate lyase superfamily protein HVS_RS08480 2b4cac10bb53c4b14ba02758659977c1 564 Gene3D G3DSA:2.160.20.10 44 488 1.3E-37 T 29-03-2018 IPR012334 Pectin lyase fold HVS_RS08480 2b4cac10bb53c4b14ba02758659977c1 564 SUPERFAMILY SSF51126 199 406 2.36E-36 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor HVS_RS08480 2b4cac10bb53c4b14ba02758659977c1 564 SUPERFAMILY SSF51126 7 21 2.36E-36 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor HVS_RS08480 2b4cac10bb53c4b14ba02758659977c1 564 SUPERFAMILY SSF51126 48 171 2.36E-36 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor HVS_RS03430 f64214765fc6b5f209af6e21a9ac504d 102 SUPERFAMILY SSF140453 5 93 1.44E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03430 f64214765fc6b5f209af6e21a9ac504d 102 Gene3D G3DSA:1.10.287.1060 1 96 1.7E-15 T 29-03-2018 HVS_RS03430 f64214765fc6b5f209af6e21a9ac504d 102 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 90 1.1E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03430 f64214765fc6b5f209af6e21a9ac504d 102 Pfam PF06013 Proteins of 100 residues with WXG 5 89 2.1E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 ProSitePatterns PS01126 Elongation factor Ts signature 1. 10 25 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 Hamap MF_00050 Elongation factor Ts [tsf]. 1 213 56.72 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 Pfam PF00889 Elongation factor TS 27 196 5.7E-46 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 Gene3D G3DSA:1.10.8.10 1 54 3.6E-24 T 29-03-2018 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 94 2.7E-37 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 92 214 2.0E-41 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 Gene3D G3DSA:3.30.479.20 60 212 5.0E-61 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 SUPERFAMILY SSF46934 2 53 2.49E-20 T 29-03-2018 IPR009060 UBA-like GO:0005515 HVS_RS06345 b6ccf40c83edbe22e025a23beb2ff4c2 215 SUPERFAMILY SSF54713 55 196 1.7E-55 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 3 739 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 271 2.2E-88 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 Gene3D G3DSA:3.40.50.300 2 159 4.9E-29 T 29-03-2018 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 Gene3D G3DSA:3.40.50.300 160 281 2.7E-37 T 29-03-2018 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 Pfam PF13361 UvrD-like helicase C-terminal domain 276 610 1.8E-78 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 SUPERFAMILY SSF52540 3 635 2.87E-187 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 Gene3D G3DSA:1.10.486.10 384 549 1.3E-51 T 29-03-2018 HVS_RS15285 8aaa2e35e5cc7fe48441b559c07f69d1 743 Gene3D G3DSA:3.40.50.300 282 383 1.9E-27 T 29-03-2018 HVS_RS07850 4cb9d01e8e22d60aeeb5409b481a0dce 382 Gene3D G3DSA:3.90.1150.10 254 377 3.5E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS07850 4cb9d01e8e22d60aeeb5409b481a0dce 382 Pfam PF00266 Aminotransferase class-V 2 369 2.4E-93 T 29-03-2018 IPR000192 Aminotransferase class V domain HVS_RS07850 4cb9d01e8e22d60aeeb5409b481a0dce 382 Gene3D G3DSA:3.40.640.10 13 253 3.6E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS07850 4cb9d01e8e22d60aeeb5409b481a0dce 382 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 2 377 5.3E-148 T 29-03-2018 IPR010969 Cysteine desulfurase-related, unknown function HVS_RS07850 4cb9d01e8e22d60aeeb5409b481a0dce 382 PIRSF PIRSF005572 1 381 1.3E-62 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HVS_RS07850 4cb9d01e8e22d60aeeb5409b481a0dce 382 SUPERFAMILY SSF53383 1 377 1.66E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 Gene3D G3DSA:3.90.79.10 2 177 1.1E-40 T 29-03-2018 HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 PRINTS PR00502 NUDIX hydrolase family signature 71 85 6.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 PRINTS PR00502 NUDIX hydrolase family signature 85 100 6.1E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 68 125 0.006 T 29-03-2018 HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 SUPERFAMILY SSF55811 6 173 2.71E-49 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 HVS_RS09530 8cb02f207682008f5a2cd5c987bc5e77 182 Pfam PF00293 NUDIX domain 44 151 3.4E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 146 167 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 187 2.0E-64 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 Gene3D G3DSA:3.40.190.10 118 212 1.1E-21 T 29-03-2018 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 Gene3D G3DSA:3.40.190.10 1 117 4.6E-41 T 29-03-2018 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 SUPERFAMILY SSF53850 2 208 5.27E-66 T 29-03-2018 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 Pfam PF01634 ATP phosphoribosyltransferase 53 207 4.0E-52 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 HVS_RS15270 e93f349476978bda823aad7e974fcf7d 213 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 211 56.32 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 Gene3D G3DSA:3.90.1150.10 1 208 1.2E-50 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 12 442 7.8E-177 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 Gene3D G3DSA:3.40.640.10 209 326 5.7E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 Gene3D G3DSA:3.90.1150.10 327 445 1.1E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 445 50.614 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 SUPERFAMILY SSF53383 7 444 1.15E-132 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 Pfam PF00202 Aminotransferase class-III 23 439 7.2E-133 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS08590 f82f2c4b8f0d2368d95a8ce124e070ce 449 PIRSF PIRSF000521 27 445 2.3E-34 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HVS_RS04075 283b2def081302205c451a7443ab745a 203 Pfam PF15428 Immunity protein 26 52 159 5.8E-16 T 29-03-2018 IPR029278 Immunity protein 26 HVS_RS15330 3f6eb5f27546db311eaf859162b777c3 250 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 143 163 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 HVS_RS15330 3f6eb5f27546db311eaf859162b777c3 250 SUPERFAMILY SSF109998 4 143 6.67E-16 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS15330 3f6eb5f27546db311eaf859162b777c3 250 SUPERFAMILY SSF54534 107 203 3.01E-31 T 29-03-2018 HVS_RS15330 3f6eb5f27546db311eaf859162b777c3 250 Gene3D G3DSA:3.10.50.40 106 230 2.2E-39 T 29-03-2018 HVS_RS15330 3f6eb5f27546db311eaf859162b777c3 250 Pfam PF13616 PPIC-type PPIASE domain 107 204 1.3E-21 T 29-03-2018 HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 SUPERFAMILY SSF51735 1 324 7.94E-90 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 317 7.6E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 PRINTS PR01713 Nucleotide sugar epimerase signature 223 238 1.6E-17 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 PRINTS PR01713 Nucleotide sugar epimerase signature 249 264 1.6E-17 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 PRINTS PR01713 Nucleotide sugar epimerase signature 28 44 1.6E-17 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 PRINTS PR01713 Nucleotide sugar epimerase signature 288 305 1.6E-17 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 Gene3D G3DSA:3.90.25.10 201 325 8.2E-36 T 29-03-2018 HVS_RS06150 5fbaef6f3305568049025a423e4fe128 327 Gene3D G3DSA:3.40.50.720 1 200 3.2E-39 T 29-03-2018 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 Gene3D G3DSA:1.10.1670.10 120 216 8.1E-29 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 Pfam PF00633 Helix-hairpin-helix motif 102 128 1.1E-9 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 PIRSF PIRSF001435 1 214 5.0E-55 T 29-03-2018 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 TIGRFAM TIGR01083 nth: endonuclease III 6 196 4.1E-82 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 SMART SM00478 40 187 1.1E-65 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 ProSitePatterns PS01155 Endonuclease III family signature. 104 133 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 Gene3D G3DSA:1.10.340.30 26 119 7.9E-26 T 29-03-2018 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 37 170 7.0E-24 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 Hamap MF_00942 Endonuclease III [nth]. 2 211 38.158 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 HVS_RS10895 c9e15c27836efe64226d288672351e52 216 SUPERFAMILY SSF48150 3 209 2.04E-69 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 SMART SM00758 628 764 2.9E-29 T 29-03-2018 IPR011658 PA14 domain HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 SMART SM00758 470 610 5.1E-7 T 29-03-2018 IPR011658 PA14 domain HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 Gene3D G3DSA:3.90.182.10 621 769 3.6E-39 T 29-03-2018 HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 Gene3D G3DSA:3.90.182.10 456 620 1.5E-34 T 29-03-2018 HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 Pfam PF07691 PA14 domain 472 608 7.6E-16 T 29-03-2018 IPR011658 PA14 domain HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 Pfam PF07691 PA14 domain 630 763 3.7E-28 T 29-03-2018 IPR011658 PA14 domain HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 SUPERFAMILY SSF56988 629 768 4.58E-44 T 29-03-2018 HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 Pfam PF12791 Anti-sigma factor N-terminus 8 61 8.3E-9 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS14710 0d6ebc748617f32d0b8e54e18de2744c 769 SUPERFAMILY SSF56988 472 615 6.02E-43 T 29-03-2018 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 Gene3D G3DSA:3.40.720.10 2 408 5.0E-30 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 395 5.4E-113 T 29-03-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 PIRSF PIRSF006392 1 404 5.3E-128 T 29-03-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 SUPERFAMILY SSF53649 191 372 1.08E-35 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 SUPERFAMILY SSF53649 1 70 1.08E-35 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 1 397 1.7E-156 T 29-03-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 37 202 8.4E-57 T 29-03-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HVS_RS10950 3a3ca19436f173769432ce3fd211134c 411 Pfam PF01676 Metalloenzyme superfamily 1 369 7.3E-40 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HVS_RS13285 505aab337ba96818530c069a242ed8d8 95 SUPERFAMILY SSF52980 9 76 2.77E-13 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HVS_RS13285 505aab337ba96818530c069a242ed8d8 95 Gene3D G3DSA:3.40.1350.10 11 88 4.7E-4 T 29-03-2018 HVS_RS13285 505aab337ba96818530c069a242ed8d8 95 SMART SM00990 1 83 1.2E-11 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 HVS_RS13285 505aab337ba96818530c069a242ed8d8 95 Pfam PF08774 VRR-NUC domain 31 82 1.3E-5 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 HVS_RS13030 b59ecdd1cc2c13873588b336182de140 477 Gene3D G3DSA:3.40.50.880 150 421 1.9E-11 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS13030 b59ecdd1cc2c13873588b336182de140 477 Gene3D G3DSA:1.20.5.510 426 476 2.7E-4 T 29-03-2018 HVS_RS13030 b59ecdd1cc2c13873588b336182de140 477 Pfam PF09822 ABC-type uncharacterized transport system 44 286 5.7E-36 T 29-03-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 HVS_RS04805 22d9b2861d4d625190d6e6b4126c12c8 245 SUPERFAMILY SSF88946 20 104 2.83E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS04805 22d9b2861d4d625190d6e6b4126c12c8 245 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 14 243 23.79 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS04805 22d9b2861d4d625190d6e6b4126c12c8 245 PIRSF PIRSF038953 3 245 1.4E-92 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS04805 22d9b2861d4d625190d6e6b4126c12c8 245 Pfam PF04542 Sigma-70 region 2 33 105 1.0E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS04805 22d9b2861d4d625190d6e6b4126c12c8 245 Gene3D G3DSA:1.10.1740.10 17 103 1.3E-13 T 29-03-2018 HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 5.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 412 5.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 5.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 5.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 Gene3D G3DSA:3.30.565.10 263 454 9.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 SMART SM00387 345 455 3.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 453 6.5E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10635 ccaedd4f681376e8d283fd1a4e93825d 456 SUPERFAMILY SSF55874 294 453 1.44E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS15390 be26fee6567865527513da654352bd53 277 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 6 272 1.0E-84 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS15390 be26fee6567865527513da654352bd53 277 Pfam PF05582 YabG peptidase U57 6 275 2.5E-96 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS15390 be26fee6567865527513da654352bd53 277 PIRSF PIRSF011575 3 276 6.8E-87 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS08090 cfb680acc867bf8c7bc0e5a4351a1bf5 118 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 117 1.8E-45 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HVS_RS08090 cfb680acc867bf8c7bc0e5a4351a1bf5 118 Pfam PF07736 Chorismate mutase type I 2 117 6.1E-49 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HVS_RS08090 cfb680acc867bf8c7bc0e5a4351a1bf5 118 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 39 117 2.0E-30 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HVS_RS08090 cfb680acc867bf8c7bc0e5a4351a1bf5 118 Gene3D G3DSA:3.30.1330.40 2 118 2.4E-50 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HVS_RS08090 cfb680acc867bf8c7bc0e5a4351a1bf5 118 PIRSF PIRSF005965 1 118 4.3E-49 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 HVS_RS08090 cfb680acc867bf8c7bc0e5a4351a1bf5 118 SUPERFAMILY SSF55298 1 117 5.89E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HVS_RS04775 4436249549c17b05928b36177c9e11c8 379 Pfam PF13007 Transposase C of IS166 homeodomain 56 127 1.9E-5 T 29-03-2018 IPR024463 Transposase TnpC, homeodomain HVS_RS04775 4436249549c17b05928b36177c9e11c8 379 Pfam PF13005 zinc-finger binding domain of transposase IS66 135 178 1.4E-12 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 HVS_RS04775 4436249549c17b05928b36177c9e11c8 379 Pfam PF03050 Transposase IS66 family 199 280 1.4E-22 T 29-03-2018 IPR004291 Transposase, IS66 HVS_RS05950 4785c69a229a1fbba227d5f4352d9f8f 89 Gene3D G3DSA:3.30.420.10 3 86 1.9E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05950 4785c69a229a1fbba227d5f4352d9f8f 89 Pfam PF00075 RNase H 6 78 5.7E-8 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HVS_RS05950 4785c69a229a1fbba227d5f4352d9f8f 89 SUPERFAMILY SSF53098 7 85 1.1E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS14875 4785c69a229a1fbba227d5f4352d9f8f 89 Gene3D G3DSA:3.30.420.10 3 86 1.9E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS14875 4785c69a229a1fbba227d5f4352d9f8f 89 Pfam PF00075 RNase H 6 78 5.7E-8 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 HVS_RS14875 4785c69a229a1fbba227d5f4352d9f8f 89 SUPERFAMILY SSF53098 7 85 1.1E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01185 2dbfdede5b29263259b26039383ca3ed 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 3 94 6.9E-26 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01185 2dbfdede5b29263259b26039383ca3ed 95 SUPERFAMILY SSF54995 2 94 1.7E-30 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01185 2dbfdede5b29263259b26039383ca3ed 95 Gene3D G3DSA:3.30.70.60 3 95 3.2E-29 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HVS_RS01185 2dbfdede5b29263259b26039383ca3ed 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 2 95 21.141 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 HVS_RS01185 2dbfdede5b29263259b26039383ca3ed 95 Pfam PF01250 Ribosomal protein S6 4 92 2.3E-29 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS07190 e34d255e86cd41da90c15d7bf98c5230 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 4.2E-22 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS07190 e34d255e86cd41da90c15d7bf98c5230 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 16 73 1.0E-6 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS07190 e34d255e86cd41da90c15d7bf98c5230 86 Gene3D G3DSA:1.20.58.110 1 86 4.0E-24 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS07190 e34d255e86cd41da90c15d7bf98c5230 86 SUPERFAMILY SSF46992 3 84 5.36E-23 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS07190 e34d255e86cd41da90c15d7bf98c5230 86 Pfam PF01649 Ribosomal protein S20 2 83 2.9E-24 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS07190 e34d255e86cd41da90c15d7bf98c5230 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 84 16.977 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 Pfam PF05343 M42 glutamyl aminopeptidase 45 331 1.6E-97 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 Gene3D G3DSA:2.40.30.40 69 157 2.2E-26 T 29-03-2018 IPR023367 Peptidase M42, domain 2 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 PIRSF PIRSF001123 2 346 2.0E-108 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 SUPERFAMILY SSF101821 70 175 3.51E-25 T 29-03-2018 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 SUPERFAMILY SSF53187 2 82 2.12E-66 T 29-03-2018 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 SUPERFAMILY SSF53187 170 338 2.12E-66 T 29-03-2018 HVS_RS07565 5e3bb4f5bb6c7e5824c088732fa884ec 349 Gene3D G3DSA:3.40.630.10 161 345 1.9E-41 T 29-03-2018 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 SUPERFAMILY SSF55874 251 382 3.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 PIRSF PIRSF003169 1 388 5.2E-142 T 29-03-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 Gene3D G3DSA:3.30.565.10 244 390 5.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 SMART SM00387 285 384 4.0E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 Pfam PF05384 Sensor protein DegS 12 169 3.8E-48 T 29-03-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 382 1.6E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 Gene3D G3DSA:1.20.5.50 1 87 3.1E-4 T 29-03-2018 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 Pfam PF07730 Histidine kinase 180 246 1.2E-18 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 381 7.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 362 7.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 335 7.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS10745 ee860b9617e7f847aa004748f39070f9 391 Gene3D G3DSA:1.20.5.340 88 196 0.21 T 29-03-2018 HVS_RS14975 88247d45f4358df57d482920af765726 282 SMART SM00382 32 234 4.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS14975 88247d45f4358df57d482920af765726 282 Gene3D G3DSA:3.40.50.300 1 236 2.0E-59 T 29-03-2018 HVS_RS14975 88247d45f4358df57d482920af765726 282 SUPERFAMILY SSF52540 3 227 7.82E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14975 88247d45f4358df57d482920af765726 282 Pfam PF00005 ABC transporter 23 162 1.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 SMART SM00322 87 155 0.0023 T 29-03-2018 IPR004087 K Homology domain GO:0003676 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 Gene3D G3DSA:3.30.30.80 4 55 2.8E-20 T 29-03-2018 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 Gene3D G3DSA:3.30.300.20 59 141 1.2E-25 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 SMART SM01245 6 58 2.3E-23 T 29-03-2018 IPR032782 Jag, N-terminal HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 SMART SM00393 127 206 1.3E-19 T 29-03-2018 IPR001374 R3H domain GO:0003676 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 Pfam PF13083 KH domain 64 133 3.1E-19 T 29-03-2018 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 SUPERFAMILY SSF54814 65 121 2.94E-5 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 Pfam PF01424 R3H domain 145 204 2.3E-18 T 29-03-2018 IPR001374 R3H domain GO:0003676 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 Gene3D G3DSA:3.30.1370.50 142 206 5.7E-20 T 29-03-2018 IPR001374 R3H domain GO:0003676 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 SUPERFAMILY SSF82708 147 204 9.29E-10 T 29-03-2018 IPR001374 R3H domain GO:0003676 HVS_RS16185 0d619fd33f304c577b5a569c9023dd68 206 Pfam PF14804 Jag N-terminus 8 57 6.9E-21 T 29-03-2018 IPR032782 Jag, N-terminal HVS_RS14065 4d35e392337493ef6e8443912be99189 182 SUPERFAMILY SSF52317 1 180 3.0E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS14065 4d35e392337493ef6e8443912be99189 182 Pfam PF01965 DJ-1/PfpI family 1 163 4.6E-46 T 29-03-2018 IPR002818 DJ-1/PfpI HVS_RS14065 4d35e392337493ef6e8443912be99189 182 Gene3D G3DSA:3.40.50.880 1 180 4.0E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS14065 4d35e392337493ef6e8443912be99189 182 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 3 176 7.6E-59 T 29-03-2018 IPR006287 Protein DJ-1 HVS_RS15075 c218ff24a40443ca3e7e96bcbef66356 61 Gene3D G3DSA:4.10.830.10 1 61 2.2E-23 T 29-03-2018 HVS_RS15075 c218ff24a40443ca3e7e96bcbef66356 61 SUPERFAMILY SSF57716 3 61 3.14E-23 T 29-03-2018 HVS_RS15075 c218ff24a40443ca3e7e96bcbef66356 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.352 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z HVS_RS15075 c218ff24a40443ca3e7e96bcbef66356 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 7.7E-26 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15075 c218ff24a40443ca3e7e96bcbef66356 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS06575 22c58157d904dc43ed6fc44d382db877 284 SMART SM00507 190 251 6.0E-5 T 29-03-2018 IPR003615 HNH nuclease HVS_RS06575 22c58157d904dc43ed6fc44d382db877 284 Gene3D G3DSA:3.40.1800.10 185 266 2.4E-9 T 29-03-2018 HVS_RS09660 8dea1e1d67bd87a5f353282834dbed73 190 Pfam PF13411 MerR HTH family regulatory protein 8 74 2.9E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS09660 8dea1e1d67bd87a5f353282834dbed73 190 Gene3D G3DSA:1.10.1660.10 5 179 9.3E-20 T 29-03-2018 HVS_RS09660 8dea1e1d67bd87a5f353282834dbed73 190 SMART SM00422 8 76 1.3E-4 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HVS_RS09660 8dea1e1d67bd87a5f353282834dbed73 190 SUPERFAMILY SSF46955 8 96 1.24E-15 T 29-03-2018 IPR009061 Putative DNA-binding domain HVS_RS08930 ff63cec311d95609e0f3eb2cecbf2a41 155 SMART SM01066 70 153 7.6E-25 T 29-03-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 HVS_RS08930 ff63cec311d95609e0f3eb2cecbf2a41 155 Pfam PF16760 Starch/carbohydrate-binding module (family 53) 74 151 1.2E-10 T 29-03-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 HVS_RS08930 ff63cec311d95609e0f3eb2cecbf2a41 155 Gene3D G3DSA:2.60.40.10 63 154 5.4E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 Gene3D G3DSA:3.90.180.10 4 60 1.3E-5 T 29-03-2018 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 328 9.5E-66 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 Gene3D G3DSA:1.10.1040.10 63 332 9.0E-120 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 2.7E-78 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 PIRSF PIRSF000116 1 206 1.0E-42 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 PIRSF PIRSF000116 203 333 4.0E-16 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 330 1.4E-140 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 SUPERFAMILY SSF51735 3 183 1.42E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 330 44.85 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 HVS_RS01150 1bb63a31f14a73c4daf72e2fc06a19b0 333 SUPERFAMILY SSF48179 184 330 1.04E-67 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 Gene3D G3DSA:3.90.1150.10 273 411 2.4E-63 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 PIRSF PIRSF000412 1 407 2.1E-179 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 Gene3D G3DSA:3.40.640.10 36 272 5.9E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 SUPERFAMILY SSF53383 4 411 1.14E-187 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 6 411 54.374 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 HVS_RS07475 303f5d3f9328f5fd6f391f110d03fcd3 411 Pfam PF00464 Serine hydroxymethyltransferase 7 383 3.2E-185 T 29-03-2018 HVS_RS11270 623dd2414883efd8b5a03d074d53064c 124 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 32 110 4.5E-23 T 29-03-2018 IPR014229 Sporulation protein YtfJ HVS_RS11270 623dd2414883efd8b5a03d074d53064c 124 PIRSF PIRSF021377 4 124 1.5E-16 T 29-03-2018 IPR014229 Sporulation protein YtfJ HVS_RS04450 ef73f28be1bb749fac4275ca14872a3c 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 1.4E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS04450 ef73f28be1bb749fac4275ca14872a3c 328 Gene3D G3DSA:3.90.25.10 176 317 8.3E-38 T 29-03-2018 HVS_RS04450 ef73f28be1bb749fac4275ca14872a3c 328 SUPERFAMILY SSF51735 2 313 2.67E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS04450 ef73f28be1bb749fac4275ca14872a3c 328 Gene3D G3DSA:3.40.50.720 2 175 3.3E-37 T 29-03-2018 HVS_RS09395 7c972d92a2e928a4509deccd5ecc46e8 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS09395 7c972d92a2e928a4509deccd5ecc46e8 123 SUPERFAMILY SSF46785 4 84 8.79E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS09395 7c972d92a2e928a4509deccd5ecc46e8 123 SMART SM00345 15 74 2.9E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS09395 7c972d92a2e928a4509deccd5ecc46e8 123 Gene3D G3DSA:1.10.10.10 2 76 5.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15825 8075b1884d16d6cfb3ce907d840488c2 313 Gene3D G3DSA:2.70.70.10 63 312 7.0E-32 T 29-03-2018 HVS_RS15825 8075b1884d16d6cfb3ce907d840488c2 313 Pfam PF01551 Peptidase family M23 208 306 1.2E-24 T 29-03-2018 IPR016047 Peptidase M23 HVS_RS15825 8075b1884d16d6cfb3ce907d840488c2 313 SUPERFAMILY SSF51261 165 310 5.75E-34 T 29-03-2018 IPR011055 Duplicated hybrid motif HVS_RS10130 8bcd4d97ee9158efb9ba8dd0323ed346 156 Pfam PF01584 CheW-like domain 11 145 5.2E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS10130 8bcd4d97ee9158efb9ba8dd0323ed346 156 SMART SM00260 7 144 9.7E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS10130 8bcd4d97ee9158efb9ba8dd0323ed346 156 SUPERFAMILY SSF50341 9 145 7.06E-38 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS10130 8bcd4d97ee9158efb9ba8dd0323ed346 156 Gene3D G3DSA:2.30.30.40 92 126 1.8E-16 T 29-03-2018 HVS_RS10130 8bcd4d97ee9158efb9ba8dd0323ed346 156 Gene3D G3DSA:2.40.50.180 25 91 2.1E-20 T 29-03-2018 HVS_RS10130 8bcd4d97ee9158efb9ba8dd0323ed346 156 Gene3D G3DSA:2.40.50.180 127 156 0.1 T 29-03-2018 HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 Pfam PF00404 Dockerin type I repeat 101 121 8.1E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 SMART SM00606 2 89 2.3E-14 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 Pfam PF03422 Carbohydrate binding module (family 6) 2 89 4.2E-23 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 SUPERFAMILY SSF63446 98 159 1.86E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 133 152 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 SUPERFAMILY SSF49785 2 89 3.89E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS08880 5bfc72382d94f32447047c240fe298c6 159 Gene3D G3DSA:2.60.120.260 1 90 3.6E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12985 31c3ef55a481c8cdbc338990c2d3af98 73 Hamap MF_00422 Protein translocase subunit SecE [secE]. 15 70 13.066 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS12985 31c3ef55a481c8cdbc338990c2d3af98 73 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 19 68 1.5E-21 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS12985 31c3ef55a481c8cdbc338990c2d3af98 73 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 18 69 1.3E-20 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 HVS_RS12985 31c3ef55a481c8cdbc338990c2d3af98 73 Gene3D G3DSA:1.20.5.1030 17 67 8.8E-22 T 29-03-2018 HVS_RS12985 31c3ef55a481c8cdbc338990c2d3af98 73 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 20 48 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 Gene3D G3DSA:2.60.40.1380 414 619 6.4E-10 T 29-03-2018 HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 SUPERFAMILY SSF49373 568 615 1.06E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 SUPERFAMILY SSF53300 37 220 1.54E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 SUPERFAMILY SSF49373 657 696 5.89E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 Pfam PF00092 von Willebrand factor type A domain 39 206 4.4E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 SMART SM00327 37 225 9.8E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 Gene3D G3DSA:3.40.50.410 35 413 1.2E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 Pfam PF02368 Bacterial Ig-like domain (group 2) 567 606 1.0E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 HVS_RS09425 73f7b7b892cd12b7f61ff074a1419cea 714 Gene3D G3DSA:2.60.40.1080 621 699 4.4E-8 T 29-03-2018 HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 Gene3D G3DSA:3.40.50.450 111 271 1.4E-40 T 29-03-2018 HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 SUPERFAMILY SSF47781 4 51 8.58E-8 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 Gene3D G3DSA:1.10.150.20 3 58 5.0E-6 T 29-03-2018 HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 Pfam PF02481 DNA recombination-mediator protein A 73 277 6.9E-81 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 285 7.6E-80 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 Gene3D G3DSA:1.10.10.10 290 368 5.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10290 03afeadd1fe3de58f0ab646e0082aee9 369 SUPERFAMILY SSF102405 81 286 7.48E-45 T 29-03-2018 HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 TIGRFAM TIGR00277 HDIG: HDIG domain 499 596 2.3E-23 T 29-03-2018 IPR006675 HDIG domain HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 Pfam PF07697 7TM-HD extracellular 53 284 4.3E-27 T 29-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 Pfam PF01966 HD domain 502 644 3.6E-19 T 29-03-2018 IPR006674 HD domain HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 Pfam PF07698 7TM receptor with intracellular HD hydrolase 297 477 5.6E-37 T 29-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 SUPERFAMILY SSF109604 500 688 6.6E-18 T 29-03-2018 HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 Gene3D G3DSA:1.10.3210.10 454 691 1.6E-32 T 29-03-2018 HVS_RS07405 d08030d77ce64c96f2544c51f0ec5fa4 729 SMART SM00471 498 654 1.7E-10 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS05035 111f51bf10aac3f5dcce35e7ffc3e36d 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 6.7E-16 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 HVS_RS14685 5e72e5b9442b1bf3e11041f00c795ac0 166 Gene3D G3DSA:3.30.70.560 1 163 3.4E-53 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HVS_RS14685 5e72e5b9442b1bf3e11041f00c795ac0 166 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 132 6.0E-37 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HVS_RS14685 5e72e5b9442b1bf3e11041f00c795ac0 166 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HVS_RS14685 5e72e5b9442b1bf3e11041f00c795ac0 166 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 132 7.3E-42 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HVS_RS14685 5e72e5b9442b1bf3e11041f00c795ac0 166 SUPERFAMILY SSF55083 3 151 1.31E-47 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 HVS_RS09925 c35554b0b8cf2d744cf399c72bce2abe 507 Pfam PF00474 Sodium:solute symporter family 34 442 2.1E-55 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 HVS_RS05850 fe5cdc1a2dc4a226039d13dfd65b0ef2 221 Pfam PF01478 Type IV leader peptidase family 79 186 5.1E-12 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 HVS_RS09685 a38e9031e0bdb04b5fdc1e0f0c3b6810 165 Gene3D G3DSA:2.30.30.40 101 147 1.9E-15 T 29-03-2018 HVS_RS09685 a38e9031e0bdb04b5fdc1e0f0c3b6810 165 SMART SM00260 16 153 9.4E-39 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS09685 a38e9031e0bdb04b5fdc1e0f0c3b6810 165 Pfam PF01584 CheW-like domain 21 155 7.4E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS09685 a38e9031e0bdb04b5fdc1e0f0c3b6810 165 SUPERFAMILY SSF50341 11 157 1.7E-39 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS09685 a38e9031e0bdb04b5fdc1e0f0c3b6810 165 Gene3D G3DSA:2.40.50.180 37 100 2.5E-22 T 29-03-2018 HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 PIRSF PIRSF033722 5 320 3.5E-27 T 29-03-2018 IPR017019 Predicted DNA replication protein, bacterial HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 Pfam PF07261 Replication initiation and membrane attachment 216 279 1.1E-13 T 29-03-2018 IPR006343 DnaD domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 Pfam PF07261 Replication initiation and membrane attachment 127 196 1.9E-16 T 29-03-2018 IPR006343 DnaD domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 Gene3D G3DSA:1.10.10.630 202 280 1.0E-16 T 29-03-2018 IPR034829 DnaD-like domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 Gene3D G3DSA:1.10.10.630 118 196 2.1E-15 T 29-03-2018 IPR034829 DnaD-like domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 SUPERFAMILY SSF158499 130 189 9.29E-13 T 29-03-2018 IPR006343 DnaD domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 SUPERFAMILY SSF158499 217 275 7.98E-14 T 29-03-2018 IPR006343 DnaD domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 217 279 5.1E-12 T 29-03-2018 IPR006343 DnaD domain HVS_RS00240 d20726b5e73ed92119bff488b104b309 323 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 127 189 9.3E-7 T 29-03-2018 IPR006343 DnaD domain HVS_RS07485 69cf4f148a838dda5a51d84eec3d764a 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 38 168 7.8E-63 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS07485 69cf4f148a838dda5a51d84eec3d764a 318 PIRSF PIRSF002849 1 312 5.9E-134 T 29-03-2018 HVS_RS07485 69cf4f148a838dda5a51d84eec3d764a 318 SUPERFAMILY SSF52540 3 283 3.55E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07485 69cf4f148a838dda5a51d84eec3d764a 318 Gene3D G3DSA:1.10.8.300 199 307 6.5E-33 T 29-03-2018 HVS_RS07485 69cf4f148a838dda5a51d84eec3d764a 318 Gene3D G3DSA:3.40.50.300 19 185 7.0E-25 T 29-03-2018 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 Gene3D G3DSA:1.10.10.10 143 217 3.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 SMART SM00448 3 118 2.2E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 SUPERFAMILY SSF52172 4 137 1.21E-20 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 SMART SM00421 147 204 3.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 Gene3D G3DSA:3.40.50.2300 2 142 3.0E-23 T 29-03-2018 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 SUPERFAMILY SSF46894 145 210 5.1E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 Pfam PF00072 Response regulator receiver domain 5 112 6.0E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 5.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 5.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 5.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS10630 51e229084f6daa2639182f62552a34bd 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 202 6.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 SUPERFAMILY SSF55315 36 109 3.06E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 SUPERFAMILY SSF75217 102 278 5.04E-52 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 39 113 7.8E-20 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 Gene3D G3DSA:3.30.1330.30 26 109 3.4E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 SMART SM00967 39 114 4.6E-20 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 39 277 5.6E-80 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 Gene3D G3DSA:3.40.1280.10 115 279 6.9E-51 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS15705 437db86e707e62f03c56ad74313cdaa7 279 Pfam PF00588 SpoU rRNA Methylase family 131 271 1.9E-42 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 SUPERFAMILY SSF100920 355 511 3.92E-65 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 308 322 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 SUPERFAMILY SSF53067 1 159 1.31E-59 T 29-03-2018 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 Gene3D G3DSA:3.30.420.40 1 171 7.0E-70 T 29-03-2018 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 167 180 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 575 2.2E-290 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 Gene3D G3DSA:1.20.1270.10 504 588 2.1E-25 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 Gene3D G3DSA:2.60.34.10 361 503 9.6E-71 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 SUPERFAMILY SSF100934 478 581 8.24E-15 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 Pfam PF00012 Hsp70 protein 4 575 7.7E-250 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 305 321 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 440 456 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 336 356 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 359 378 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 PRINTS PR00301 70kDa heat shock protein signature 173 183 1.2E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 612 37.412 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 Gene3D G3DSA:3.30.420.40 172 334 2.3E-53 T 29-03-2018 HVS_RS11105 a9259acd16094bfd19bccdd62d73aab8 619 SUPERFAMILY SSF53067 161 353 8.25E-70 T 29-03-2018 HVS_RS03600 c4d1d686785f6b459521bb4debcdb4bc 76 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 44 55 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HVS_RS03600 c4d1d686785f6b459521bb4debcdb4bc 76 Pfam PF00082 Subtilase family 39 70 3.5E-5 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS03600 c4d1d686785f6b459521bb4debcdb4bc 76 Gene3D G3DSA:3.40.50.200 6 76 8.3E-13 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS03600 c4d1d686785f6b459521bb4debcdb4bc 76 SUPERFAMILY SSF52743 20 68 1.83E-12 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS10395 90674c17e4c5ac5ae980467481aa88b0 214 Gene3D G3DSA:3.40.50.150 7 145 6.3E-9 T 29-03-2018 HVS_RS10395 90674c17e4c5ac5ae980467481aa88b0 214 Pfam PF03059 Nicotianamine synthase protein 27 146 1.1E-6 T 29-03-2018 IPR004298 Nicotianamine synthase GO:0030410|GO:0030418 MetaCyc: PWY-5912|MetaCyc: PWY-5957 HVS_RS10395 90674c17e4c5ac5ae980467481aa88b0 214 SUPERFAMILY SSF53335 32 153 8.33E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13835 b7c2d3d87ecbce7942b2990acc0c71ef 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 12 365 4.5E-66 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS13835 b7c2d3d87ecbce7942b2990acc0c71ef 367 Pfam PF03845 Spore germination protein 13 329 1.7E-48 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS02265 c16a2dcf358fca99e0b7283193df3c5f 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 207 1.5E-54 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 HVS_RS02265 c16a2dcf358fca99e0b7283193df3c5f 213 Pfam PF01081 KDPG and KHG aldolase 9 199 1.2E-42 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 HVS_RS02265 c16a2dcf358fca99e0b7283193df3c5f 213 SUPERFAMILY SSF51569 3 208 3.48E-62 T 29-03-2018 HVS_RS02265 c16a2dcf358fca99e0b7283193df3c5f 213 Gene3D G3DSA:3.20.20.70 4 213 2.5E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS14815 b79933eae0cecfa61371d5e45388d7ab 163 Pfam PF05130 FlgN protein 10 153 5.5E-13 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HVS_RS14815 b79933eae0cecfa61371d5e45388d7ab 163 SUPERFAMILY SSF140566 10 127 2.22E-6 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HVS_RS14815 b79933eae0cecfa61371d5e45388d7ab 163 Gene3D G3DSA:1.20.58.300 8 136 1.6E-11 T 29-03-2018 HVS_RS06010 b79933eae0cecfa61371d5e45388d7ab 163 Pfam PF05130 FlgN protein 10 153 5.5E-13 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HVS_RS06010 b79933eae0cecfa61371d5e45388d7ab 163 SUPERFAMILY SSF140566 10 127 2.22E-6 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HVS_RS06010 b79933eae0cecfa61371d5e45388d7ab 163 Gene3D G3DSA:1.20.58.300 8 136 1.6E-11 T 29-03-2018 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 Pfam PF00404 Dockerin type I repeat 472 492 2.6E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 Pfam PF00404 Dockerin type I repeat 508 528 2.7E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 SUPERFAMILY SSF52743 189 459 1.17E-82 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 472 491 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 PRINTS PR00723 Subtilisin serine protease family (S8) signature 398 414 3.0E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 PRINTS PR00723 Subtilisin serine protease family (S8) signature 209 228 3.0E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 PRINTS PR00723 Subtilisin serine protease family (S8) signature 247 260 3.0E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 SUPERFAMILY SSF63446 466 534 6.57E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 Gene3D G3DSA:1.10.1330.10 466 538 7.1E-5 T 29-03-2018 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 399 409 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 Gene3D G3DSA:3.40.50.200 151 460 1.3E-82 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 251 261 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 Pfam PF00082 Subtilase family 210 446 2.0E-43 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS07720 e2a26d1678a1a9e028e46de13b06e1d7 538 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 214 225 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 Gene3D G3DSA:3.40.50.300 528 877 2.4E-18 T 29-03-2018 HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 SUPERFAMILY SSF52540 610 702 3.6E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 SUPERFAMILY SSF52540 526 579 3.6E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 SUPERFAMILY SSF52540 295 451 3.6E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 Pfam PF08797 HIRAN domain 1061 1151 3.9E-10 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 Gene3D G3DSA:3.40.50.300 67 468 5.8E-24 T 29-03-2018 HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 SMART SM00487 273 478 3.8E-18 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 Pfam PF00271 Helicase conserved C-terminal domain 545 688 2.2E-7 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 SMART SM00910 1060 1156 3.6E-10 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 Pfam PF00270 DEAD/DEAH box helicase 300 449 1.8E-21 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS00810 8c9e61ba0c25ebc4a7362e23fde5b62b 1156 SMART SM00490 594 688 9.4E-9 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS07870 24a7ea53ed7235c2ab5cb3dd24fa877d 470 Pfam PF01554 MatE 22 185 1.8E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS07870 24a7ea53ed7235c2ab5cb3dd24fa877d 470 Pfam PF01554 MatE 272 403 5.1E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS07870 24a7ea53ed7235c2ab5cb3dd24fa877d 470 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 415 2.4E-60 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS07870 24a7ea53ed7235c2ab5cb3dd24fa877d 470 PIRSF PIRSF006603 1 453 3.0E-92 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS13780 3a2cf13b8ed760da3c1e4b699425f388 62 Gene3D G3DSA:1.10.1660.20 2 47 7.6E-6 T 29-03-2018 HVS_RS13780 3a2cf13b8ed760da3c1e4b699425f388 62 Pfam PF12728 Helix-turn-helix domain 3 44 2.6E-7 T 29-03-2018 HVS_RS02920 5bd928e4585559b43bd3d97eac0fb75a 591 Pfam PF05569 BlaR1 peptidase M56 9 339 3.9E-52 T 29-03-2018 IPR008756 Peptidase M56 HVS_RS08935 4ae656f38cf578463d3dd2165f34c2a2 241 Gene3D G3DSA:3.40.50.300 7 236 1.6E-57 T 29-03-2018 HVS_RS08935 4ae656f38cf578463d3dd2165f34c2a2 241 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS08935 4ae656f38cf578463d3dd2165f34c2a2 241 Pfam PF00005 ABC transporter 24 156 2.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS08935 4ae656f38cf578463d3dd2165f34c2a2 241 SMART SM00382 33 206 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08935 4ae656f38cf578463d3dd2165f34c2a2 241 SUPERFAMILY SSF52540 9 214 2.01E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 Gene3D G3DSA:3.30.420.40 200 338 4.8E-11 T 29-03-2018 HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 SUPERFAMILY SSF53067 10 169 1.29E-11 T 29-03-2018 HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 Pfam PF11104 Type IV pilus assembly protein PilM; 13 340 2.2E-33 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 Gene3D G3DSA:3.30.420.40 5 170 9.2E-24 T 29-03-2018 HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 PIRSF PIRSF019169 1 367 1.1E-93 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 8 344 5.8E-40 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 SMART SM00842 10 174 0.0064 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HVS_RS11505 e7c2f55786e1ba9e4481468886df6b1e 367 SUPERFAMILY SSF53067 203 364 6.56E-20 T 29-03-2018 HVS_RS00825 a004d6a73805493ad26d4b9a0ed87aeb 285 Gene3D G3DSA:1.10.10.10 177 268 6.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00825 a004d6a73805493ad26d4b9a0ed87aeb 285 Pfam PF08722 TnsA endonuclease N terminal 75 169 8.0E-19 T 29-03-2018 IPR014833 TnsA endonuclease, N-terminal HVS_RS00825 a004d6a73805493ad26d4b9a0ed87aeb 285 Pfam PF08721 TnsA endonuclease C terminal 172 254 3.0E-20 T 29-03-2018 IPR014832 TnsA endonuclease C-terminal HVS_RS00825 a004d6a73805493ad26d4b9a0ed87aeb 285 SUPERFAMILY SSF52980 8 173 4.08E-57 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HVS_RS00825 a004d6a73805493ad26d4b9a0ed87aeb 285 Gene3D G3DSA:3.40.1350.10 7 173 2.5E-44 T 29-03-2018 HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 SUPERFAMILY SSF143597 14 142 2.62E-30 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 25 136 4.9E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 Gene3D G3DSA:1.10.150.20 275 353 7.6E-9 T 29-03-2018 HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 4 354 43.46 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 Pfam PF10635 DisA bacterial checkpoint controller linker region 142 280 1.0E-53 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 Gene3D G3DSA:3.40.1700.10 6 142 1.3E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 Pfam PF12826 Helix-hairpin-helix motif 297 342 3.3E-6 T 29-03-2018 HVS_RS12595 dcab0b75f7b05f196859aecc03e0a3f0 358 SUPERFAMILY SSF47781 279 345 2.41E-12 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS08760 961bfd80b8ebf6edbec31e2e552b611d 209 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 60 88 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 HVS_RS08760 961bfd80b8ebf6edbec31e2e552b611d 209 SUPERFAMILY SSF53955 37 202 1.27E-39 T 29-03-2018 IPR023346 Lysozyme-like domain HVS_RS08760 961bfd80b8ebf6edbec31e2e552b611d 209 Gene3D G3DSA:1.10.530.10 25 205 3.2E-33 T 29-03-2018 HVS_RS08760 961bfd80b8ebf6edbec31e2e552b611d 209 Pfam PF01464 Transglycosylase SLT domain 49 165 4.4E-27 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 HVS_RS02480 0e51c726f33889d7e84f2442d2fd04db 297 Hamap MF_00663 Phosphatidylserine decarboxylase proenzyme [psd]. 1 294 40.814 T 29-03-2018 IPR033179 Phosphatidylserine decarboxylase, prokaryotic type 2 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 HVS_RS02480 0e51c726f33889d7e84f2442d2fd04db 297 Pfam PF02666 Phosphatidylserine decarboxylase 86 292 6.4E-55 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 HVS_RS02480 0e51c726f33889d7e84f2442d2fd04db 297 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 77 276 6.1E-36 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 HVS_RS07490 2e8012a140e6c048d477bf82d61c4eab 935 SMART SM00460 677 748 1.3E-19 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS07490 2e8012a140e6c048d477bf82d61c4eab 935 Pfam PF01841 Transglutaminase-like superfamily 631 746 1.0E-26 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS07490 2e8012a140e6c048d477bf82d61c4eab 935 SUPERFAMILY SSF54001 608 747 5.47E-39 T 29-03-2018 HVS_RS07490 2e8012a140e6c048d477bf82d61c4eab 935 Gene3D G3DSA:3.90.260.10 618 753 6.5E-26 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS01980 32026375f9ce63443674d16827c17960 202 Pfam PF07591 Pretoxin HINT domain 2 91 1.6E-22 T 29-03-2018 HVS_RS01980 32026375f9ce63443674d16827c17960 202 Gene3D G3DSA:2.170.16.10 1 92 3.4E-23 T 29-03-2018 HVS_RS01980 32026375f9ce63443674d16827c17960 202 SUPERFAMILY SSF51294 10 91 1.59E-17 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS01980 32026375f9ce63443674d16827c17960 202 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 67 90 1.7E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS14905 fdfa5d463b3cfb7e02767cb8e2da8cc4 427 SUPERFAMILY SSF116734 9 194 2.45E-28 T 29-03-2018 HVS_RS14905 fdfa5d463b3cfb7e02767cb8e2da8cc4 427 SUPERFAMILY SSF116734 219 420 9.16E-55 T 29-03-2018 HVS_RS14905 fdfa5d463b3cfb7e02767cb8e2da8cc4 427 Gene3D G3DSA:3.90.220.20 161 406 2.8E-55 T 29-03-2018 HVS_RS14905 fdfa5d463b3cfb7e02767cb8e2da8cc4 427 Gene3D G3DSA:3.90.220.20 5 159 1.4E-20 T 29-03-2018 HVS_RS14905 fdfa5d463b3cfb7e02767cb8e2da8cc4 427 Pfam PF01420 Type I restriction modification DNA specificity domain 234 407 4.5E-29 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS14905 fdfa5d463b3cfb7e02767cb8e2da8cc4 427 Pfam PF01420 Type I restriction modification DNA specificity domain 6 151 4.1E-15 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 SMART SM00278 199 218 0.022 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 SMART SM00278 229 248 51.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 Pfam PF12836 Helix-hairpin-helix motif 190 250 2.7E-23 T 29-03-2018 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 Gene3D G3DSA:3.10.560.10 60 195 5.8E-12 T 29-03-2018 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 Gene3D G3DSA:1.10.150.320 196 252 7.2E-24 T 29-03-2018 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 190 251 1.3E-19 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 Pfam PF10531 SLBB domain 73 117 6.6E-12 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS06280 a8eb2101d5b0a54496f3ed85d4138263 252 SUPERFAMILY SSF47781 187 251 8.67E-28 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 Gene3D G3DSA:3.40.50.150 59 269 4.5E-40 T 29-03-2018 HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 SUPERFAMILY SSF46955 5 52 1.06E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 SUPERFAMILY SSF53335 68 250 7.7E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 Pfam PF12728 Helix-turn-helix domain 6 52 1.2E-12 T 29-03-2018 HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 Pfam PF13847 Methyltransferase domain 100 214 1.8E-23 T 29-03-2018 IPR025714 Methyltransferase domain HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 Gene3D G3DSA:1.10.10.10 5 58 5.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12230 ebe3dbed1ca0ba55c43cc53012a783b0 272 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 52 8.0E-11 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 SUPERFAMILY SSF63446 496 562 8.63E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 SUPERFAMILY SSF51445 35 412 7.88E-63 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 45 401 1.4E-60 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 Gene3D G3DSA:3.20.20.80 32 417 1.2E-47 T 29-03-2018 HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 ProSitePatterns PS00018 EF-hand calcium-binding domain. 533 545 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 192 201 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 HVS_RS06910 a75d64d66dc90f6d848a5a7ee01fe952 564 Gene3D G3DSA:1.10.1330.10 493 564 1.2E-4 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SMART SM00283 410 657 2.6E-82 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Pfam PF17202 Single cache domain 3 57 153 3.0E-24 T 29-03-2018 IPR033463 Single cache domain 3 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 469 624 1.3E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SUPERFAMILY SSF58104 377 664 1.28E-65 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Gene3D G3DSA:1.10.287.950 180 461 4.2E-12 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Gene3D G3DSA:1.10.287.950 462 661 3.3E-45 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SUPERFAMILY SSF103190 8 58 8.63E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SUPERFAMILY SSF103190 88 150 3.73E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SUPERFAMILY SSF158472 183 230 2.09E-10 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Pfam PF00672 HAMP domain 184 229 7.9E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Gene3D G3DSA:3.30.450.20 60 151 0.0017 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 Gene3D G3DSA:3.30.450.20 2 59 7.6E-6 T 29-03-2018 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SMART SM00304 182 234 8.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS02580 19f5e5699b032198c6a95eab417809bd 706 SMART SM00304 312 364 7.4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HVS_RS06515 c383040687f58d80822cacc5af3fc8dc 852 Gene3D G3DSA:3.40.720.10 12 718 3.9E-4 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS06515 c383040687f58d80822cacc5af3fc8dc 852 SUPERFAMILY SSF53649 450 641 3.27E-6 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS06515 c383040687f58d80822cacc5af3fc8dc 852 Pfam PF08665 PglZ domain 461 636 9.6E-58 T 29-03-2018 IPR013973 PglZ domain HVS_RS06515 c383040687f58d80822cacc5af3fc8dc 852 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 22 841 1.9E-215 T 29-03-2018 IPR014060 Conserved hypothetical protein CHP02687 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 SUPERFAMILY SSF52172 1 131 1.57E-36 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 Gene3D G3DSA:1.10.10.10 127 217 5.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 1.3E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.3E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 Pfam PF00072 Response regulator receiver domain 4 115 8.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 Gene3D G3DSA:3.40.50.2300 1 126 1.2E-35 T 29-03-2018 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 SMART SM00448 2 115 5.8E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 SUPERFAMILY SSF46894 155 216 1.05E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS14395 40cef605b884958b1ea22b7a2c87fd7f 217 SMART SM00421 154 211 2.8E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 Gene3D G3DSA:2.60.40.10 399 476 0.025 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 124 135 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 Gene3D G3DSA:3.40.50.200 56 380 1.5E-91 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 PRINTS PR00723 Subtilisin serine protease family (S8) signature 317 333 4.6E-9 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 173 4.6E-9 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 PRINTS PR00723 Subtilisin serine protease family (S8) signature 119 138 4.6E-9 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 Pfam PF00082 Subtilase family 121 368 1.9E-45 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS09415 dcd9bd5631175c161f53cd750f96ed0e 814 SUPERFAMILY SSF52743 98 376 1.15E-82 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 Gene3D G3DSA:1.20.1560.10 2 321 1.3E-62 T 29-03-2018 HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 SUPERFAMILY SSF90123 4 322 5.76E-69 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 SMART SM00382 365 551 5.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 SUPERFAMILY SSF52540 329 575 1.01E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 Pfam PF00664 ABC transporter transmembrane region 18 289 1.9E-36 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 Pfam PF00005 ABC transporter 356 505 1.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS12555 be94a2faa7ad2e21c2662579686ab5b1 584 Gene3D G3DSA:3.40.50.300 325 580 2.6E-67 T 29-03-2018 HVS_RS08350 9c076b610337452f69a2a0389fd2f5cd 199 Gene3D G3DSA:1.25.40.10 79 190 1.0E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS08350 9c076b610337452f69a2a0389fd2f5cd 199 SUPERFAMILY SSF81901 108 190 7.85E-6 T 29-03-2018 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 PRINTS PR00046 Major sigma-70 factor signature 215 226 3.7E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 PRINTS PR00046 Major sigma-70 factor signature 179 191 3.7E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 PRINTS PR00046 Major sigma-70 factor signature 80 93 3.7E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 PRINTS PR00046 Major sigma-70 factor signature 200 215 3.7E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 12 230 4.1E-109 T 29-03-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 PIRSF PIRSF000770 10 234 2.4E-74 T 29-03-2018 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 Pfam PF04545 Sigma-70, region 4 177 227 8.5E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 230 5.9E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 80 93 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 Gene3D G3DSA:1.10.601.10 20 124 1.3E-29 T 29-03-2018 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 Gene3D G3DSA:1.10.1270.10 146 233 2.6E-22 T 29-03-2018 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 Pfam PF04542 Sigma-70 region 2 56 125 3.6E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 200 226 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 SUPERFAMILY SSF88946 22 125 3.79E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS06305 51cabbccc2baad006c3bb383246bcab7 235 SUPERFAMILY SSF88659 141 232 3.92E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS07825 1509a21b2b2d0fafa0fb4e3a9b832c1a 279 Gene3D G3DSA:2.60.40.680 118 279 1.6E-40 T 29-03-2018 HVS_RS07825 1509a21b2b2d0fafa0fb4e3a9b832c1a 279 Pfam PF00963 Cohesin domain 121 274 1.6E-25 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS07825 1509a21b2b2d0fafa0fb4e3a9b832c1a 279 SUPERFAMILY SSF49384 116 273 1.76E-50 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS07000 d9ed860ea93c34b016f1d7f6c6f7d0bd 216 Gene3D G3DSA:3.40.1190.10 1 216 4.0E-16 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS07000 d9ed860ea93c34b016f1d7f6c6f7d0bd 216 Pfam PF08245 Mur ligase middle domain 15 202 2.7E-10 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS07000 d9ed860ea93c34b016f1d7f6c6f7d0bd 216 SUPERFAMILY SSF53623 3 214 1.01E-11 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 Pfam PF00404 Dockerin type I repeat 72 92 9.8E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 Gene3D G3DSA:3.40.50.1110 116 347 1.4E-35 T 29-03-2018 HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 ProSitePatterns PS00018 EF-hand calcium-binding domain. 72 84 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 117 343 1.3E-50 T 29-03-2018 IPR005181 Sialate O-acetylesterase domain HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 SUPERFAMILY SSF63446 35 102 2.55E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 72 91 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 Gene3D G3DSA:1.10.1330.10 37 103 4.2E-5 T 29-03-2018 HVS_RS12455 c71889c4ed2c5d018b48ff9a4b1b1868 348 SUPERFAMILY SSF52266 117 346 3.48E-50 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 Gene3D G3DSA:3.10.450.120 165 195 5.9E-19 T 29-03-2018 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 Gene3D G3DSA:3.10.450.120 360 397 3.2E-18 T 29-03-2018 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 SUPERFAMILY SSF116734 196 393 2.29E-38 T 29-03-2018 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 SUPERFAMILY SSF116734 6 198 1.23E-23 T 29-03-2018 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 Gene3D G3DSA:3.90.220.20 196 359 1.6E-32 T 29-03-2018 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 Gene3D G3DSA:3.90.220.20 3 164 2.2E-15 T 29-03-2018 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 Pfam PF01420 Type I restriction modification DNA specificity domain 28 180 2.8E-15 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS15870 a1f5f92f0e310be9552017a97e1bd295 397 Pfam PF01420 Type I restriction modification DNA specificity domain 199 377 5.9E-20 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS10310 e028dc9c82b24a2c9537aa38dbd25b3f 81 Gene3D G3DSA:2.30.30.240 1 78 2.1E-20 T 29-03-2018 HVS_RS10310 e028dc9c82b24a2c9537aa38dbd25b3f 81 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 76 4.3E-28 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH HVS_RS10310 e028dc9c82b24a2c9537aa38dbd25b3f 81 Pfam PF05239 PRC-barrel domain 2 79 3.4E-18 T 29-03-2018 IPR027275 PRC-barrel domain HVS_RS10310 e028dc9c82b24a2c9537aa38dbd25b3f 81 SUPERFAMILY SSF50346 2 74 7.59E-17 T 29-03-2018 IPR011033 PRC-barrel-like HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 44.634 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 Pfam PF08502 LeuA allosteric (dimerisation) domain 371 499 7.2E-37 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 Pfam PF00682 HMGL-like 4 273 1.0E-101 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 SUPERFAMILY SSF51569 1 291 4.94E-103 T 29-03-2018 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 Gene3D G3DSA:3.20.20.70 1 332 9.6E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 SUPERFAMILY SSF110921 395 499 6.41E-25 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 SMART SM00917 370 500 6.0E-37 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS01155 585e02d4443e00f00e717f5cb43602cb 509 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 497 6.3E-228 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 Gene3D G3DSA:3.40.50.300 112 345 2.9E-28 T 29-03-2018 HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 SUPERFAMILY SSF52540 277 319 6.86E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 SUPERFAMILY SSF52540 392 526 6.86E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 Pfam PF08463 EcoEI R protein C-terminal 635 789 4.8E-33 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 SMART SM00487 162 357 1.1E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 29 110 2.3E-9 T 29-03-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 SUPERFAMILY SSF52540 152 361 8.62E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 Pfam PF04851 Type III restriction enzyme, res subunit 165 322 9.8E-43 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS14915 ad00b13b1fb4500fb18e6d7dd19e4e31 791 Gene3D G3DSA:3.40.50.300 393 541 2.0E-9 T 29-03-2018 HVS_RS05495 570b043f28c7febec4fb3cf1e485d425 229 Pfam PF04239 Protein of unknown function (DUF421) 86 201 1.5E-36 T 29-03-2018 IPR007353 Protein of unknown function DUF421 HVS_RS05495 570b043f28c7febec4fb3cf1e485d425 229 Gene3D G3DSA:3.30.240.20 158 224 2.0E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain HVS_RS05495 570b043f28c7febec4fb3cf1e485d425 229 Gene3D G3DSA:3.30.240.20 79 148 3.7E-25 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain HVS_RS09015 d59f3b2bc4abb16b771b60fbf3ffdff9 260 Pfam PF04542 Sigma-70 region 2 49 119 6.4E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09015 d59f3b2bc4abb16b771b60fbf3ffdff9 260 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 29 256 25.461 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS09015 d59f3b2bc4abb16b771b60fbf3ffdff9 260 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 35 254 3.6E-55 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS09015 d59f3b2bc4abb16b771b60fbf3ffdff9 260 SUPERFAMILY SSF88946 35 118 1.06E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09015 d59f3b2bc4abb16b771b60fbf3ffdff9 260 PIRSF PIRSF038953 19 259 3.1E-68 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS09015 d59f3b2bc4abb16b771b60fbf3ffdff9 260 Gene3D G3DSA:1.10.1740.10 32 117 8.1E-13 T 29-03-2018 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 430 574 4.2E-18 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 116 313 1.1E-40 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 305 464 4.1E-12 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 562 693 6.2E-11 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Gene3D G3DSA:2.160.20.20 382 782 2.4E-4 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 SUPERFAMILY SSF63446 28 93 2.06E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 64 83 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Pfam PF00404 Dockerin type I repeat 32 52 7.5E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12815 c9550b29b33d21e4917594cc648f6577 790 Pfam PF00404 Dockerin type I repeat 64 84 2.4E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 9 134 34.746 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 Pfam PF00411 Ribosomal protein S11 24 133 4.3E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 SUPERFAMILY SSF53137 19 134 1.63E-50 T 29-03-2018 HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 Gene3D G3DSA:3.30.420.80 8 134 5.0E-45 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.3E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS15005 c4ea2388ed15da554e316ed1bb289457 134 PIRSF PIRSF002131 3 134 7.3E-54 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 SUPERFAMILY SSF50985 114 361 1.57E-76 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:3.10.100.10 706 758 3.9E-21 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:3.10.100.10 546 602 8.9E-7 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:3.10.100.10 759 813 3.2E-7 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:3.10.100.10 656 705 8.8E-20 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:3.10.100.10 603 655 2.5E-15 T 29-03-2018 IPR016186 C-type lectin-like/link domain HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 170 180 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 SUPERFAMILY SSF50985 306 537 8.76E-54 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 47 66 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00404 Dockerin type I repeat 47 66 8.9E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00404 Dockerin type I repeat 83 103 7.3E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 183 229 5.7E-12 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 382 429 7.8E-9 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 432 479 1.1E-9 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 282 329 1.6E-11 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 578 630 1.1E-4 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 735 770 7.9E-8 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 232 279 3.9E-14 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 133 180 2.6E-7 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 684 732 2.6E-14 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 633 681 8.2E-8 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:2.130.10.30 378 545 4.8E-45 T 29-03-2018 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 SUPERFAMILY SSF63446 43 112 3.43E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 186 202 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 285 299 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 233 249 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 269 285 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 428 449 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 135 151 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 167 180 1.6E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 620 630 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:2.130.10.30 100 215 3.8E-30 T 29-03-2018 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 Gene3D G3DSA:2.130.10.30 216 377 7.5E-62 T 29-03-2018 HVS_RS12370 bbd13f1449a04a253ae0077ee553f913 814 SUPERFAMILY SSF50985 547 812 2.53E-67 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II HVS_RS15710 a5cc2599e6d337d79ff71bddca2cc14c 159 Gene3D G3DSA:1.10.1520.10 14 148 3.1E-18 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS15710 a5cc2599e6d337d79ff71bddca2cc14c 159 PIRSF PIRSF005520 11 146 4.9E-51 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family HVS_RS15710 a5cc2599e6d337d79ff71bddca2cc14c 159 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 17 143 30.231 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family HVS_RS15710 a5cc2599e6d337d79ff71bddca2cc14c 159 SMART SM00535 8 143 0.0038 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS15710 a5cc2599e6d337d79ff71bddca2cc14c 159 Pfam PF00636 Ribonuclease III domain 27 124 1.8E-16 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS15710 a5cc2599e6d337d79ff71bddca2cc14c 159 SUPERFAMILY SSF69065 20 135 1.24E-37 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 15 325 31.601 T 29-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 SMART SM00471 71 194 3.8E-13 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 SUPERFAMILY SSF109604 27 329 8.83E-86 T 29-03-2018 HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 Pfam PF01966 HD domain 75 184 5.3E-19 T 29-03-2018 IPR006674 HD domain HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 Pfam PF13286 Phosphohydrolase-associated domain 236 322 1.5E-25 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 38 164 1.9E-49 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 HVS_RS09295 b9caaa850bbcdc3a7d95e6f14699b3de 331 Gene3D G3DSA:1.10.3210.10 28 328 3.1E-81 T 29-03-2018 HVS_RS06880 3c1641eb9ecb61e1961128788055f21b 392 Gene3D G3DSA:3.90.1150.10 278 392 3.1E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS06880 3c1641eb9ecb61e1961128788055f21b 392 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 387 3.6E-151 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 HVS_RS06880 3c1641eb9ecb61e1961128788055f21b 392 Gene3D G3DSA:3.40.640.10 94 277 1.6E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS06880 3c1641eb9ecb61e1961128788055f21b 392 Gene3D G3DSA:3.90.1150.10 1 93 1.3E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS06880 3c1641eb9ecb61e1961128788055f21b 392 SUPERFAMILY SSF53383 1 389 2.1E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS06880 3c1641eb9ecb61e1961128788055f21b 392 Pfam PF00155 Aminotransferase class I and II 54 383 1.2E-36 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 Gene3D G3DSA:2.60.40.10 704 764 1.1E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 Gene3D G3DSA:2.60.40.10 866 976 4.5E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 Gene3D G3DSA:2.60.40.10 766 865 4.7E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 SUPERFAMILY SSF49265 723 871 3.95E-13 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 Gene3D G3DSA:2.60.40.10 261 357 0.36 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 Gene3D G3DSA:2.60.40.10 25 242 1.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 SMART SM00060 875 956 6.3 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 SMART SM00060 772 856 0.0079 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 SMART SM00060 517 751 0.43 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 SMART SM00060 381 484 14.0 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 SUPERFAMILY SSF49265 861 967 1.97E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS15500 40176fe8e99b571eb8c014a817287ef6 1352 Gene3D G3DSA:2.60.40.10 358 517 1.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 SUPERFAMILY SSF52540 8 200 3.31E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 Hamap MF_00367 GTPase Era [era]. 3 295 37.572 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 154 2.3E-28 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 Pfam PF07650 KH domain 206 284 6.9E-18 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 Gene3D G3DSA:3.40.50.300 4 53 2.1E-15 T 29-03-2018 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 Gene3D G3DSA:3.40.50.300 54 192 1.5E-18 T 29-03-2018 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 SUPERFAMILY SSF54814 179 296 6.54E-41 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 TIGRFAM TIGR00436 era: GTP-binding protein Era 6 278 2.6E-88 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 Gene3D G3DSA:3.30.300.20 193 297 1.5E-43 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS07425 7a620dd5293195ac7737ae1a6f59fe9a 297 Pfam PF01926 50S ribosome-binding GTPase 8 123 3.6E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS01215 ee542bc4cad8f35c8808724bbf434f46 941 Gene3D G3DSA:2.60.120.430 561 724 1.8E-30 T 29-03-2018 HVS_RS01215 ee542bc4cad8f35c8808724bbf434f46 941 Pfam PF09992 Phosphodiester glycosidase 212 388 1.7E-35 T 29-03-2018 IPR018711 Phosphodiester glycosidase HVS_RS01215 ee542bc4cad8f35c8808724bbf434f46 941 Gene3D G3DSA:3.60.21.10 725 906 4.2E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS01215 ee542bc4cad8f35c8808724bbf434f46 941 Gene3D G3DSA:2.60.40.1080 481 560 4.3E-6 T 29-03-2018 HVS_RS01215 ee542bc4cad8f35c8808724bbf434f46 941 Gene3D G3DSA:2.60.40.1080 393 477 7.3E-4 T 29-03-2018 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 85 204 1.6E-46 T 29-03-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Gene3D G3DSA:1.10.1140.10 447 547 5.3E-31 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 SUPERFAMILY SSF47917 448 531 1.1E-23 T 29-03-2018 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 SUPERFAMILY SSF52540 171 441 8.08E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Gene3D G3DSA:2.40.50.100 116 167 6.9E-24 T 29-03-2018 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 2 588 52.399 T 29-03-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 4 581 2.2E-294 T 29-03-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 69 5.6E-14 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 213 436 1.8E-92 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 Gene3D G3DSA:3.40.50.300 168 436 2.4E-102 T 29-03-2018 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 427 436 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS01260 ad673857d4324d2f4de0dda4647fb2d1 593 SUPERFAMILY SSF50615 3 71 6.54E-13 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 SMART SM00382 423 600 3.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 SUPERFAMILY SSF46785 679 745 8.89E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 SUPERFAMILY SSF52540 361 651 1.27E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 Pfam PF01580 FtsK/SpoIIIE family 388 526 7.0E-49 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 15 155 1.6E-7 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 SMART SM00843 679 744 6.1E-39 T 29-03-2018 IPR018541 FtsK gamma domain HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 Pfam PF09397 Ftsk gamma domain 681 742 1.2E-29 T 29-03-2018 IPR018541 FtsK gamma domain HVS_RS07270 8bd857160291f3d82639e14eea19636a 755 Gene3D G3DSA:3.40.50.300 206 754 1.3E-56 T 29-03-2018 HVS_RS02375 4932225b82ea719c99f70f53219bc6d6 364 Pfam PF13616 PPIC-type PPIASE domain 202 319 2.7E-11 T 29-03-2018 HVS_RS02375 4932225b82ea719c99f70f53219bc6d6 364 SUPERFAMILY SSF109998 51 230 1.69E-11 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS02375 4932225b82ea719c99f70f53219bc6d6 364 SUPERFAMILY SSF54534 231 322 1.96E-10 T 29-03-2018 HVS_RS02375 4932225b82ea719c99f70f53219bc6d6 364 Gene3D G3DSA:1.10.4030.10 46 194 1.7E-8 T 29-03-2018 HVS_RS02375 4932225b82ea719c99f70f53219bc6d6 364 Gene3D G3DSA:3.10.50.40 205 354 3.5E-16 T 29-03-2018 HVS_RS10785 ab883932b499d9bc44ff70d5ee9ad2a3 450 Pfam PF05673 Protein of unknown function (DUF815) 193 445 2.1E-100 T 29-03-2018 IPR008533 Domain of unknown function DUF815 HVS_RS10785 ab883932b499d9bc44ff70d5ee9ad2a3 450 SUPERFAMILY SSF52540 142 416 3.21E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10785 ab883932b499d9bc44ff70d5ee9ad2a3 450 Gene3D G3DSA:3.40.50.300 203 413 1.2E-15 T 29-03-2018 HVS_RS10785 ab883932b499d9bc44ff70d5ee9ad2a3 450 SMART SM00382 244 361 4.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS09320 7594a3c59ad3b0270a4b4d9aa582ad2b 279 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 6 266 6.0E-98 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HVS_RS09320 7594a3c59ad3b0270a4b4d9aa582ad2b 279 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 261 3.1E-108 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HVS_RS09320 7594a3c59ad3b0270a4b4d9aa582ad2b 279 SUPERFAMILY SSF51621 4 266 8.64E-102 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HVS_RS09320 7594a3c59ad3b0270a4b4d9aa582ad2b 279 PIRSF PIRSF000388 1 269 3.7E-108 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HVS_RS09320 7594a3c59ad3b0270a4b4d9aa582ad2b 279 Gene3D G3DSA:3.20.20.60 1 266 9.2E-77 T 29-03-2018 HVS_RS09320 7594a3c59ad3b0270a4b4d9aa582ad2b 279 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 5 266 41.61 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 HVS_RS03035 c9877245000dddaa49c70845a1211240 175 Pfam PF04986 Putative transposase 3 64 7.4E-18 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS10145 6a25d8b38ee9b63d95442c5007f56521 222 Pfam PF12945 Flagellar protein YcgR 7 90 2.3E-15 T 29-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal HVS_RS10145 6a25d8b38ee9b63d95442c5007f56521 222 Pfam PF07238 PilZ domain 99 213 6.4E-18 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS10145 6a25d8b38ee9b63d95442c5007f56521 222 Gene3D G3DSA:2.40.10.220 101 217 6.2E-26 T 29-03-2018 HVS_RS10145 6a25d8b38ee9b63d95442c5007f56521 222 Gene3D G3DSA:2.30.110.10 5 100 1.9E-10 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 HVS_RS10145 6a25d8b38ee9b63d95442c5007f56521 222 SUPERFAMILY SSF141371 133 218 4.32E-6 T 29-03-2018 HVS_RS15530 164a96abb171f18a682cf9f1429fc69f 92 PIRSF PIRSF010606 1 81 7.3E-31 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB HVS_RS15530 164a96abb171f18a682cf9f1429fc69f 92 Pfam PF12652 CotJB protein 6 80 2.3E-29 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 Gene3D G3DSA:3.40.50.2000 3 263 2.3E-5 T 29-03-2018 HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 Hamap MF_00484 Glycogen synthase [glgA]. 4 477 44.881 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 Gene3D G3DSA:3.40.50.2000 264 473 5.8E-29 T 29-03-2018 HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 Pfam PF08323 Starch synthase catalytic domain 5 240 1.2E-86 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 5 476 5.1E-171 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 Pfam PF00534 Glycosyl transferases group 1 297 443 1.6E-11 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS05150 365e7c5577e86a9f9bcdba55279a9f6d 481 SUPERFAMILY SSF53756 3 479 1.74E-125 T 29-03-2018 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 Pfam PF16990 Carbohydrate binding module (family 35) 60 163 5.0E-14 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 Pfam PF02156 Glycosyl hydrolase family 26 178 491 5.4E-77 T 29-03-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 555 574 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 PRINTS PR00739 Glycosyl hydrolase family 26 signature 358 381 1.6E-22 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 PRINTS PR00739 Glycosyl hydrolase family 26 signature 260 274 1.6E-22 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 PRINTS PR00739 Glycosyl hydrolase family 26 signature 331 348 1.6E-22 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 PRINTS PR00739 Glycosyl hydrolase family 26 signature 393 405 1.6E-22 T 29-03-2018 IPR000805 Glycoside hydrolase family 26 GO:0006080|GO:0016985 KEGG: 00051+3.2.1.78|MetaCyc: PWY-7456 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 SUPERFAMILY SSF51445 175 501 1.4E-66 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 Gene3D G3DSA:3.20.20.80 169 495 4.8E-108 T 29-03-2018 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 SUPERFAMILY SSF63446 516 584 4.81E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 Pfam PF00404 Dockerin type I repeat 555 575 2.0E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09375 9956b1a0e015319a056a8c3b43727772 586 Gene3D G3DSA:2.60.120.260 25 166 3.5E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12005 360d831e263bae4342715dbe547af2ad 234 SUPERFAMILY SSF56214 37 125 4.06E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS12005 360d831e263bae4342715dbe547af2ad 234 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 132 203 2.3E-8 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS12005 360d831e263bae4342715dbe547af2ad 234 Gene3D G3DSA:3.90.470.20 141 214 1.7E-7 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS12005 360d831e263bae4342715dbe547af2ad 234 Gene3D G3DSA:3.90.470.20 25 140 6.8E-17 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS12005 360d831e263bae4342715dbe547af2ad 234 SUPERFAMILY SSF56214 132 203 6.41E-13 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 HVS_RS00395 70a178bdf0f4db134c894033c555c7c9 266 SUPERFAMILY SSF56300 115 253 6.22E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS00395 70a178bdf0f4db134c894033c555c7c9 266 SMART SM00854 116 266 1.3E-12 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA HVS_RS00395 70a178bdf0f4db134c894033c555c7c9 266 Gene3D G3DSA:3.60.21.10 85 258 3.6E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS00395 70a178bdf0f4db134c894033c555c7c9 266 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 116 256 5.4E-40 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA HVS_RS09300 de9fe8570ee35203f5449842fb59eb2f 344 SMART SM00471 125 261 2.4E-13 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS09300 de9fe8570ee35203f5449842fb59eb2f 344 SUPERFAMILY SSF109604 121 289 9.2E-39 T 29-03-2018 HVS_RS09300 de9fe8570ee35203f5449842fb59eb2f 344 Pfam PF01966 HD domain 130 252 6.9E-20 T 29-03-2018 IPR006674 HD domain HVS_RS09300 de9fe8570ee35203f5449842fb59eb2f 344 TIGRFAM TIGR00277 HDIG: HDIG domain 127 219 4.9E-8 T 29-03-2018 IPR006675 HDIG domain HVS_RS09300 de9fe8570ee35203f5449842fb59eb2f 344 Gene3D G3DSA:1.10.3210.10 28 295 6.7E-44 T 29-03-2018 HVS_RS14110 2fccaec17a811cbd475f3edb0b0b0c96 320 Gene3D G3DSA:3.40.50.410 73 291 1.8E-41 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14110 2fccaec17a811cbd475f3edb0b0b0c96 320 Pfam PF00092 von Willebrand factor type A domain 81 275 2.6E-28 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14110 2fccaec17a811cbd475f3edb0b0b0c96 320 SUPERFAMILY SSF53300 76 218 8.01E-34 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14110 2fccaec17a811cbd475f3edb0b0b0c96 320 SUPERFAMILY SSF53300 249 277 8.01E-34 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14110 2fccaec17a811cbd475f3edb0b0b0c96 320 SMART SM00327 79 258 1.4E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 8 191 2.4E-70 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 SUPERFAMILY SSF52540 19 195 1.26E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 195 28.511 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 Pfam PF01926 50S ribosome-binding GTPase 27 145 1.5E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 Gene3D G3DSA:3.40.50.300 73 197 2.2E-12 T 29-03-2018 HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 27 192 6.8E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS07135 2d6c043060adb1a5e4fe32004347a79a 199 Gene3D G3DSA:3.40.50.300 4 72 1.4E-14 T 29-03-2018 HVS_RS12635 34493e0ec411988bccc4e2407a5fee2c 342 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 44 243 1.2E-71 T 29-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 HVS_RS12635 34493e0ec411988bccc4e2407a5fee2c 342 Gene3D G3DSA:3.30.590.10 2 245 1.4E-84 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 HVS_RS12635 34493e0ec411988bccc4e2407a5fee2c 342 ProSitePatterns PS00112 Phosphagen kinase active site signature. 157 163 - T 29-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 HVS_RS12635 34493e0ec411988bccc4e2407a5fee2c 342 Hamap MF_00602 Protein-arginine kinase [mcsB]. 3 340 35.893 T 29-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 HVS_RS12635 34493e0ec411988bccc4e2407a5fee2c 342 SUPERFAMILY SSF55931 3 258 5.33E-86 T 29-03-2018 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 3.8E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 3.8E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 3.8E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 3.8E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 Gene3D G3DSA:1.10.10.10 5 122 1.5E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03730 8337a0da836804f615e7e508470535fe 122 SUPERFAMILY SSF46785 23 114 4.51E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03730 8337a0da836804f615e7e508470535fe 122 SMART SM00418 39 117 9.8E-29 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 Pfam PF01022 Bacterial regulatory protein, arsR family 46 91 3.7E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS03730 8337a0da836804f615e7e508470535fe 122 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 Gene3D G3DSA:3.30.70.270 454 630 3.6E-50 T 29-03-2018 HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 SUPERFAMILY SSF55073 466 624 2.28E-41 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 SMART SM00267 450 623 1.0E-51 T 29-03-2018 IPR000160 GGDEF domain HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 Pfam PF00990 Diguanylate cyclase, GGDEF domain 461 618 9.2E-44 T 29-03-2018 IPR000160 GGDEF domain HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 459 621 1.7E-37 T 29-03-2018 IPR000160 GGDEF domain HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 Gene3D G3DSA:3.20.20.450 632 886 1.1E-94 T 29-03-2018 IPR001633 EAL domain HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 SMART SM00052 633 879 1.6E-106 T 29-03-2018 IPR001633 EAL domain HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 SUPERFAMILY SSF141868 638 887 5.75E-89 T 29-03-2018 IPR001633 EAL domain HVS_RS13930 0048acdf19bae655b875f5631fed7830 910 Pfam PF00563 EAL domain 639 873 4.5E-70 T 29-03-2018 IPR001633 EAL domain HVS_RS09815 e8d751e38c065383294ba8577feab0a0 236 Pfam PF02348 Cytidylyltransferase 6 138 7.1E-23 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 HVS_RS09815 e8d751e38c065383294ba8577feab0a0 236 SUPERFAMILY SSF53448 3 232 3.43E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09815 e8d751e38c065383294ba8577feab0a0 236 Gene3D G3DSA:3.90.550.10 2 233 1.1E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09125 73d499924a9e61af686fd57201bdacc3 601 Gene3D G3DSA:3.40.50.410 83 369 9.7E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09125 73d499924a9e61af686fd57201bdacc3 601 SUPERFAMILY SSF53300 88 202 1.31E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09125 73d499924a9e61af686fd57201bdacc3 601 Pfam PF13519 von Willebrand factor type A domain 90 192 2.7E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09125 73d499924a9e61af686fd57201bdacc3 601 Pfam PF07584 Aerotolerance regulator N-terminal 1 78 6.9E-22 T 29-03-2018 IPR024163 Aerotolerance regulator, N-terminal HVS_RS09125 73d499924a9e61af686fd57201bdacc3 601 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 81 1.7E-7 T 29-03-2018 IPR011933 Double transmembrane domain HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 Gene3D G3DSA:3.90.640.10 189 245 5.6E-33 T 29-03-2018 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 Pfam PF06723 MreB/Mbl protein 6 330 3.9E-156 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 2.2E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 2.2E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 2.2E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 2.2E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 2.2E-62 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 SUPERFAMILY SSF53067 143 323 1.94E-51 T 29-03-2018 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 Gene3D G3DSA:3.30.420.40 3 153 1.4E-41 T 29-03-2018 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 SUPERFAMILY SSF53067 4 140 6.74E-43 T 29-03-2018 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 330 3.1E-158 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 Gene3D G3DSA:3.30.420.40 154 188 0.002 T 29-03-2018 HVS_RS05375 77d9474c194bd81af22faca5de513d01 340 Gene3D G3DSA:3.30.420.40 246 311 2.5E-12 T 29-03-2018 HVS_RS12640 78e8937487aa2afbb123f7e5d3469cbc 170 PIRSF PIRSF015034 1 169 4.7E-55 T 29-03-2018 IPR025542 YacH protein HVS_RS12640 78e8937487aa2afbb123f7e5d3469cbc 170 SUPERFAMILY SSF46600 127 163 6.15E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS12640 78e8937487aa2afbb123f7e5d3469cbc 170 Pfam PF02151 UvrB/uvrC motif 130 163 2.0E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS12640 78e8937487aa2afbb123f7e5d3469cbc 170 Gene3D G3DSA:4.10.860.10 78 165 1.0E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 HVS_RS11040 84b999a51188aef95a06299a56976d9d 629 Pfam PF00963 Cohesin domain 39 187 2.0E-21 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS11040 84b999a51188aef95a06299a56976d9d 629 Gene3D G3DSA:2.60.40.680 36 195 3.5E-33 T 29-03-2018 HVS_RS11040 84b999a51188aef95a06299a56976d9d 629 SUPERFAMILY SSF49384 35 188 7.33E-39 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS11040 84b999a51188aef95a06299a56976d9d 629 Pfam PF00395 S-layer homology domain 510 552 2.1E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11040 84b999a51188aef95a06299a56976d9d 629 Pfam PF00395 S-layer homology domain 451 494 2.9E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS11040 84b999a51188aef95a06299a56976d9d 629 Pfam PF00395 S-layer homology domain 577 620 1.9E-6 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 Gene3D G3DSA:1.10.287.130 101 204 1.8E-7 T 29-03-2018 HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 SMART SM00388 123 191 2.0E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 PRINTS PR00344 Bacterial sensor protein C-terminal signature 268 282 1.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 317 1.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 323 7.3E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 Pfam PF00512 His Kinase A (phospho-acceptor) domain 127 190 5.0E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 Gene3D G3DSA:3.30.565.10 205 336 3.6E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 SMART SM00387 233 336 3.3E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 SUPERFAMILY SSF55874 190 330 7.07E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS03000 2be8cbaf7164a67be34f152c6b72306d 336 SUPERFAMILY SSF47384 110 187 1.51E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS12420 3cd9fcb298fb0805754f8a1336a03343 225 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 224 19.032 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS12420 3cd9fcb298fb0805754f8a1336a03343 225 SUPERFAMILY SSF56104 1 216 1.54E-52 T 29-03-2018 HVS_RS12420 3cd9fcb298fb0805754f8a1336a03343 225 Gene3D G3DSA:3.30.200.20 1 100 4.0E-20 T 29-03-2018 HVS_RS12420 3cd9fcb298fb0805754f8a1336a03343 225 Gene3D G3DSA:3.30.470.20 101 221 4.7E-30 T 29-03-2018 HVS_RS12420 3cd9fcb298fb0805754f8a1336a03343 225 Pfam PF01259 SAICAR synthetase 4 213 2.0E-33 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 Gene3D G3DSA:3.30.230.10 76 166 2.6E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 6.6E-70 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 35.879 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 Gene3D G3DSA:3.30.160.20 10 72 5.1E-29 T 29-03-2018 HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 SUPERFAMILY SSF54768 7 76 4.71E-23 T 29-03-2018 HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 1.9E-30 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 SUPERFAMILY SSF54211 80 159 4.3E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS15055 c20d8a6d29e7a9d3fd5354fc7900a7cc 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 2.9E-33 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 HVS_RS14715 db8ff0cd661331b7f2e38efc356eb29c 250 Gene3D G3DSA:1.10.1740.10 18 105 1.3E-13 T 29-03-2018 HVS_RS14715 db8ff0cd661331b7f2e38efc356eb29c 250 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 15 244 26.102 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS14715 db8ff0cd661331b7f2e38efc356eb29c 250 PIRSF PIRSF038953 5 249 6.4E-79 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS14715 db8ff0cd661331b7f2e38efc356eb29c 250 Pfam PF07638 ECF sigma factor 14 110 3.5E-5 T 29-03-2018 IPR011517 RNA polymerase sigma-70 ECF-like HVS_RS14715 db8ff0cd661331b7f2e38efc356eb29c 250 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 21 242 2.5E-55 T 29-03-2018 IPR014244 RNA polymerase sigma-I type HVS_RS14715 db8ff0cd661331b7f2e38efc356eb29c 250 SUPERFAMILY SSF88946 21 105 1.59E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 Gene3D G3DSA:3.40.91.30 558 659 2.5E-14 T 29-03-2018 HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 Gene3D G3DSA:3.40.50.300 233 521 2.9E-41 T 29-03-2018 HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 SMART SM00487 19 229 5.1E-19 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 SMART SM00490 265 346 1.8E-30 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 SUPERFAMILY SSF52540 62 364 6.07E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 Gene3D G3DSA:3.40.50.300 1 232 7.5E-29 T 29-03-2018 HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 Pfam PF00271 Helicase conserved C-terminal domain 237 345 2.2E-24 T 29-03-2018 IPR001650 Helicase, C-terminal HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 22 465 1.5E-79 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 HVS_RS13475 c08ea84e140608d0a0a432017d2efb54 665 Pfam PF00270 DEAD/DEAH box helicase 25 197 2.7E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 SUPERFAMILY SSF55200 88 172 2.35E-32 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 4 173 28.275 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 172 7.9E-38 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 80 2.9E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 173 1.7E-64 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 Gene3D G3DSA:3.10.20.80 6 82 1.3E-28 T 29-03-2018 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 Gene3D G3DSA:3.30.110.10 83 173 2.2E-35 T 29-03-2018 HVS_RS06395 003eb9776fdda1556c72fc1bbc459e1c 173 SUPERFAMILY SSF54364 9 82 8.5E-27 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 HVS_RS00120 9292591bba872bfbb4cdb087d59c0b57 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 2.8E-73 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HVS_RS00120 9292591bba872bfbb4cdb087d59c0b57 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 367 1.9E-30 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HVS_RS00120 9292591bba872bfbb4cdb087d59c0b57 394 SUPERFAMILY SSF52518 5 251 5.89E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS00120 9292591bba872bfbb4cdb087d59c0b57 394 Gene3D G3DSA:3.40.50.970 3 251 4.8E-52 T 29-03-2018 HVS_RS00120 9292591bba872bfbb4cdb087d59c0b57 394 SUPERFAMILY SSF52922 252 377 5.71E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS00120 9292591bba872bfbb4cdb087d59c0b57 394 Gene3D G3DSA:3.40.50.920 252 386 2.6E-27 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS06235 96433a07890a76d69ebd3a007e9cfe04 208 SUPERFAMILY SSF53328 2 203 3.66E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS06235 96433a07890a76d69ebd3a007e9cfe04 208 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 198 9.1E-63 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 HVS_RS06235 96433a07890a76d69ebd3a007e9cfe04 208 Gene3D G3DSA:3.40.50.170 2 204 8.0E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS06235 96433a07890a76d69ebd3a007e9cfe04 208 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 195 30.804 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 HVS_RS06235 96433a07890a76d69ebd3a007e9cfe04 208 Pfam PF00551 Formyl transferase 3 189 1.4E-50 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS00140 20d185d42c17c3e4771884b5538084ec 239 Pfam PF01381 Helix-turn-helix 9 69 8.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS00140 20d185d42c17c3e4771884b5538084ec 239 SMART SM00530 94 153 86.0 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS00140 20d185d42c17c3e4771884b5538084ec 239 SMART SM00530 7 69 4.1E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS00140 20d185d42c17c3e4771884b5538084ec 239 SUPERFAMILY SSF47413 2 71 3.22E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS00140 20d185d42c17c3e4771884b5538084ec 239 Gene3D G3DSA:1.10.260.40 96 198 6.1E-7 T 29-03-2018 HVS_RS00140 20d185d42c17c3e4771884b5538084ec 239 Gene3D G3DSA:1.10.260.40 1 74 1.1E-13 T 29-03-2018 HVS_RS09155 fea610500deba8192a0da1e902d26b86 831 SUPERFAMILY SSF52317 188 343 1.69E-10 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS09155 fea610500deba8192a0da1e902d26b86 831 Gene3D G3DSA:3.40.50.880 179 345 4.3E-10 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 Hamap MF_01074 UPF0272 protein . 1 466 40.14 T 29-03-2018 IPR002822 Uncharacterised protein family UPF0272 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 Gene3D G3DSA:3.30.70.1380 324 406 2.5E-34 T 29-03-2018 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 PRINTS PR00334 HMW kininogen signature 79 100 4.3E-8 T 29-03-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 PRINTS PR00334 HMW kininogen signature 104 127 4.3E-8 T 29-03-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 PRINTS PR00334 HMW kininogen signature 132 154 4.3E-8 T 29-03-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 Pfam PF01969 Protein of unknown function DUF111 4 458 4.1E-142 T 29-03-2018 IPR035108 LarC/UPF0272 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 Gene3D G3DSA:3.10.20.300 408 466 6.6E-17 T 29-03-2018 HVS_RS11215 4af75114e8e4929db5b1bdd69cd05008 466 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 147 458 6.6E-98 T 29-03-2018 IPR002822 Uncharacterised protein family UPF0272 HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 SUPERFAMILY SSF53383 123 488 2.99E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 SUPERFAMILY SSF46785 11 83 1.63E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 81 5.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 Gene3D G3DSA:1.10.10.10 5 83 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 Gene3D G3DSA:3.90.1150.10 395 488 9.2E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 Pfam PF00155 Aminotransferase class I and II 141 484 4.4E-25 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 SMART SM00345 22 81 1.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS14055 858c013ff55cbfc595bc55281cb747d6 488 Gene3D G3DSA:3.40.640.10 143 394 4.5E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 SUPERFAMILY SSF58104 275 556 5.75E-67 T 29-03-2018 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 Gene3D G3DSA:1.10.287.950 361 559 4.2E-48 T 29-03-2018 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 Gene3D G3DSA:1.10.287.950 16 360 1.5E-15 T 29-03-2018 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 SUPERFAMILY SSF58104 10 128 3.66E-5 T 29-03-2018 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 SMART SM00283 308 555 2.0E-88 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 483 512 6.0E-43 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 329 358 6.0E-43 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 433 6.0E-43 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 6.0E-43 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS13095 e49c9ce380ebc721fd90f9e8742b5a0e 602 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 367 522 6.2E-53 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 SUPERFAMILY SSF74650 1620 1888 7.85E-74 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Pfam PF06165 Glycosyltransferase family 36 1638 1885 2.2E-72 T 29-03-2018 IPR010383 Glycosyl hydrolase 94 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Pfam PF06165 Glycosyltransferase family 36 2141 2378 2.3E-78 T 29-03-2018 IPR010383 Glycosyl hydrolase 94 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 SMART SM01068 2118 2183 1.3E-35 T 29-03-2018 IPR009342 Putative carbohydrate binding domain HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 SMART SM01068 1614 1675 3.3E-20 T 29-03-2018 IPR009342 Putative carbohydrate binding domain HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Gene3D G3DSA:2.60.420.10 2827 2910 1.9E-23 T 29-03-2018 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2409 2835 1.3E-132 T 29-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 SUPERFAMILY SSF74650 2118 2380 5.02E-80 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 SUPERFAMILY SSF48208 2386 2910 6.32E-107 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Gene3D G3DSA:2.70.98.40 2119 2392 3.8E-88 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Gene3D G3DSA:2.70.98.40 1618 1900 2.8E-75 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Gene3D G3DSA:1.50.10.10 2424 2801 3.0E-84 T 29-03-2018 HVS_RS06415 de1a9d5aa50981c404f68e1acd2aa491 2910 Pfam PF10091 Putative glucoamylase 1373 1585 1.1E-16 T 29-03-2018 IPR019282 Domain of unknown function DUF2329 HVS_RS00310 e231ca3a3788db3798a3bd984624269b 507 Pfam PF00801 PKD domain 282 339 6.2E-12 T 29-03-2018 IPR000601 PKD domain HVS_RS00310 e231ca3a3788db3798a3bd984624269b 507 SUPERFAMILY SSF49299 267 350 7.46E-21 T 29-03-2018 IPR000601 PKD domain HVS_RS00310 e231ca3a3788db3798a3bd984624269b 507 SMART SM00089 270 353 6.2E-17 T 29-03-2018 IPR022409 PKD/Chitinase domain HVS_RS00310 e231ca3a3788db3798a3bd984624269b 507 Gene3D G3DSA:2.60.40.10 263 356 1.5E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00310 e231ca3a3788db3798a3bd984624269b 507 Gene3D G3DSA:2.60.120.260 357 507 1.0E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 Gene3D G3DSA:4.10.520.10 1 91 2.0E-36 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 SUPERFAMILY SSF47729 1 90 2.5E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 SMART SM00411 1 90 7.8E-46 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.4E-36 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.8E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.8E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.8E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 HVS_RS11940 ebacd764fcdb94b15120fe1b6e6badf0 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HVS_RS11650 15435208c55ecc503b997898c5feafbf 375 Gene3D G3DSA:3.90.226.10 167 347 2.3E-25 T 29-03-2018 HVS_RS11650 15435208c55ecc503b997898c5feafbf 375 SMART SM00245 166 344 3.2E-6 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS11650 15435208c55ecc503b997898c5feafbf 375 SUPERFAMILY SSF52096 144 334 4.64E-23 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS11650 15435208c55ecc503b997898c5feafbf 375 Pfam PF03572 Peptidase family S41 195 324 1.1E-21 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS07715 f399fe525546b8eb182755c3635c0d90 217 Pfam PF16316 Domain of unknown function (DUF4956) 22 124 1.5E-12 T 29-03-2018 IPR032531 Protein of unknown function DUF4956 HVS_RS15555 23e05b01df917a727d45754bd38dc4e6 152 PIRSF PIRSF005384 1 147 1.7E-64 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HVS_RS15555 23e05b01df917a727d45754bd38dc4e6 152 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 3 144 1.6E-63 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 HVS_RS15555 23e05b01df917a727d45754bd38dc4e6 152 Gene3D G3DSA:3.40.1400.10 1 152 1.6E-70 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HVS_RS15555 23e05b01df917a727d45754bd38dc4e6 152 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 8.5E-63 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HVS_RS15555 23e05b01df917a727d45754bd38dc4e6 152 SUPERFAMILY SSF89623 1 144 5.62E-63 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HVS_RS15555 23e05b01df917a727d45754bd38dc4e6 152 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.1E-61 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 HVS_RS01065 2e1fc56f57d9afc31873452e084ae223 356 Gene3D G3DSA:3.30.420.10 145 339 7.3E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01065 2e1fc56f57d9afc31873452e084ae223 356 SUPERFAMILY SSF53098 151 303 2.78E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01065 2e1fc56f57d9afc31873452e084ae223 356 SUPERFAMILY SSF46689 51 133 4.84E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS01065 2e1fc56f57d9afc31873452e084ae223 356 Pfam PF00665 Integrase core domain 158 272 3.2E-18 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS13875 7f2b74931ee6b48856a6af295def18e1 487 PIRSF PIRSF005690 1 487 1.6E-175 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS13875 7f2b74931ee6b48856a6af295def18e1 487 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 13 477 6.7E-188 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 Gene3D G3DSA:1.10.1330.10 477 547 1.5E-5 T 29-03-2018 HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 SUPERFAMILY SSF49785 330 467 1.28E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 SUPERFAMILY SSF51445 31 308 1.54E-52 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 Gene3D G3DSA:2.60.120.260 336 471 1.1E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 Pfam PF00754 F5/8 type C domain 357 462 9.6E-23 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 Gene3D G3DSA:3.20.20.80 25 320 6.0E-33 T 29-03-2018 HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 283 4.6E-18 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 HVS_RS15835 e40baed01da6a5d7863463c66d534257 547 SUPERFAMILY SSF63446 478 546 2.45E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 10 326 5.5E-76 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 Pfam PF01895 PhoU domain 357 444 2.0E-18 T 29-03-2018 IPR026022 PhoU domain HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 Pfam PF01895 PhoU domain 467 547 6.7E-16 T 29-03-2018 IPR026022 PhoU domain HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 Gene3D G3DSA:1.20.58.220 341 458 2.3E-25 T 29-03-2018 HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 SUPERFAMILY SSF109755 338 549 7.12E-51 T 29-03-2018 HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 Pfam PF02690 Na+/Pi-cotransporter 149 268 3.0E-17 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 Pfam PF02690 Na+/Pi-cotransporter 20 155 1.1E-51 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 HVS_RS05200 e3ebc54df0dc08b828e152785f5cae4f 570 Gene3D G3DSA:1.20.58.220 459 563 7.0E-22 T 29-03-2018 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 SUPERFAMILY SSF52540 140 437 3.38E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 PIRSF PIRSF006485 2 440 2.3E-182 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Gene3D G3DSA:3.30.300.20 354 436 1.6E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 2.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 74 92 2.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Hamap MF_00195 GTPase Der [der]. 3 438 41.593 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Gene3D G3DSA:3.40.50.300 225 353 3.8E-25 T 29-03-2018 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Gene3D G3DSA:3.40.50.300 73 224 7.0E-41 T 29-03-2018 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 355 435 4.2E-35 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 SUPERFAMILY SSF52540 6 170 1.58E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Pfam PF01926 50S ribosome-binding GTPase 179 297 3.1E-28 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Pfam PF01926 50S ribosome-binding GTPase 6 121 3.1E-30 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 435 1.9E-182 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 159 5.8E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 178 346 1.1E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS10660 9a7701531621adb91049b0658a0bead3 440 Gene3D G3DSA:1.20.120.430 1 72 1.3E-19 T 29-03-2018 HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 Gene3D G3DSA:1.50.10.10 327 589 1.3E-55 T 29-03-2018 HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 Pfam PF03190 Protein of unknown function, DUF255 8 168 4.0E-77 T 29-03-2018 IPR004879 Domain of unknown function DUF255 HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 Gene3D G3DSA:1.50.10.10 175 326 2.7E-20 T 29-03-2018 HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 SUPERFAMILY SSF48208 194 538 3.52E-90 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 SUPERFAMILY SSF52833 4 134 5.85E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 Gene3D G3DSA:3.40.30.10 5 174 1.1E-31 T 29-03-2018 HVS_RS05195 32a944bf23c407e41d6bc26c0483236b 678 PIRSF PIRSF006402 1 678 9.2E-248 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 HVS_RS08390 a278bc1a07ab7f9a4cfde6f1f3efd990 288 Pfam PF08443 RimK-like ATP-grasp domain 124 268 3.7E-21 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 HVS_RS08390 a278bc1a07ab7f9a4cfde6f1f3efd990 288 Gene3D G3DSA:3.30.1490.20 101 159 4.7E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HVS_RS08390 a278bc1a07ab7f9a4cfde6f1f3efd990 288 Gene3D G3DSA:3.30.470.20 160 265 7.2E-18 T 29-03-2018 HVS_RS08390 a278bc1a07ab7f9a4cfde6f1f3efd990 288 Gene3D G3DSA:3.40.50.20 1 100 8.9E-13 T 29-03-2018 HVS_RS08390 a278bc1a07ab7f9a4cfde6f1f3efd990 288 SUPERFAMILY SSF56059 87 280 2.53E-36 T 29-03-2018 HVS_RS12025 613f86505cbd17dbf750c7cbbd50b1e7 351 Gene3D G3DSA:3.40.47.10 23 228 3.3E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12025 613f86505cbd17dbf750c7cbbd50b1e7 351 SUPERFAMILY SSF53901 22 351 1.82E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12025 613f86505cbd17dbf750c7cbbd50b1e7 351 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 263 350 1.2E-21 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS12025 613f86505cbd17dbf750c7cbbd50b1e7 351 Gene3D G3DSA:3.40.47.10 229 351 1.8E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 HVS_RS12025 613f86505cbd17dbf750c7cbbd50b1e7 351 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 130 206 2.9E-12 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 HVS_RS07200 0428de30aca57bfdf6b47a12d6c66f4e 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 7.0E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS12210 0428de30aca57bfdf6b47a12d6c66f4e 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 7.0E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS04340 0428de30aca57bfdf6b47a12d6c66f4e 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 7.0E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS02950 0428de30aca57bfdf6b47a12d6c66f4e 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 7.0E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS03320 0428de30aca57bfdf6b47a12d6c66f4e 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 7.0E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 SMART SM00382 428 620 1.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 SUPERFAMILY SSF52540 392 636 4.17E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 Gene3D G3DSA:1.20.1560.10 17 359 5.5E-77 T 29-03-2018 HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 Gene3D G3DSA:3.40.50.300 390 640 2.2E-70 T 29-03-2018 HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 ProSitePatterns PS00211 ABC transporters family signature. 540 554 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 Pfam PF00005 ABC transporter 419 568 1.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 SUPERFAMILY SSF90123 23 355 3.53E-77 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS12550 0d8f99c39b7e758156905bfd718127f7 642 Pfam PF00664 ABC transporter transmembrane region 39 304 1.1E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 SUPERFAMILY SSF51445 147 683 3.16E-250 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 Pfam PF07477 Glycosyl hydrolase family 67 C-terminus 457 680 5.2E-99 T 29-03-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 Gene3D G3DSA:3.30.379.10 17 140 3.4E-19 T 29-03-2018 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 Gene3D G3DSA:3.20.20.80 145 477 1.7E-165 T 29-03-2018 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 PIRSF PIRSF029900 1 683 0.0 T 29-03-2018 IPR011395 Alpha glucuronidase GO:0005576|GO:0045493|GO:0046559 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 Pfam PF07488 Glycosyl hydrolase family 67 middle domain 129 456 2.9E-164 T 29-03-2018 IPR011100 Glycosyl hydrolase family 67, catalytic domain GO:0005576|GO:0045493|GO:0046559 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 Pfam PF03648 Glycosyl hydrolase family 67 N-terminus 4 125 1.2E-27 T 29-03-2018 IPR005154 Alpha glucuronidase, N-terminal GO:0045493|GO:0046559 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 Gene3D G3DSA:3.90.1330.10 478 680 3.1E-88 T 29-03-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 HVS_RS02310 323e8a953cce7fda12c0533a294a98c2 683 SUPERFAMILY SSF55545 2 144 5.76E-30 T 29-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 HVS_RS10350 965fb2bfdbc5ea49d490c68594531a3f 317 Gene3D G3DSA:3.65.10.10 116 317 2.5E-41 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS10350 965fb2bfdbc5ea49d490c68594531a3f 317 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 306 2.7E-73 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS10350 965fb2bfdbc5ea49d490c68594531a3f 317 SUPERFAMILY SSF55205 6 315 6.7E-98 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HVS_RS10350 965fb2bfdbc5ea49d490c68594531a3f 317 Gene3D G3DSA:3.65.10.10 1 115 3.9E-26 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS10350 965fb2bfdbc5ea49d490c68594531a3f 317 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 7 315 2.8E-120 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS11690 21530b4654ba40c0b4f8ebef4f480702 869 Pfam PF01841 Transglutaminase-like superfamily 317 430 3.1E-15 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS11690 21530b4654ba40c0b4f8ebef4f480702 869 SMART SM00460 365 433 5.3E-5 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS11690 21530b4654ba40c0b4f8ebef4f480702 869 Gene3D G3DSA:3.90.260.10 300 433 8.6E-4 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS11690 21530b4654ba40c0b4f8ebef4f480702 869 SUPERFAMILY SSF54001 307 435 5.72E-15 T 29-03-2018 HVS_RS11690 21530b4654ba40c0b4f8ebef4f480702 869 Gene3D G3DSA:2.60.40.10 437 539 0.0012 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS07810 56b14d09f138914a5e8549a36c100e7d 228 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 108 132 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site HVS_RS07810 56b14d09f138914a5e8549a36c100e7d 228 SUPERFAMILY SSF109635 17 103 3.14E-13 T 29-03-2018 HVS_RS07810 56b14d09f138914a5e8549a36c100e7d 228 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 103 137 2.5E-10 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 HVS_RS07810 56b14d09f138914a5e8549a36c100e7d 228 SUPERFAMILY SSF57716 105 138 4.56E-8 T 29-03-2018 HVS_RS07810 56b14d09f138914a5e8549a36c100e7d 228 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 21 176 3.4E-44 T 29-03-2018 IPR014240 Regulatory protein, YteA family HVS_RS01690 aae1a8bdda094dcc58464e165cf29ecc 272 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 184 201 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site HVS_RS01690 aae1a8bdda094dcc58464e165cf29ecc 272 Pfam PF01618 MotA/TolQ/ExbB proton channel family 99 217 5.2E-24 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 HVS_RS15350 faf8a224b0b1d01b8a77f73da6d076f7 295 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 107 262 1.7E-23 T 29-03-2018 HVS_RS15350 faf8a224b0b1d01b8a77f73da6d076f7 295 SUPERFAMILY SSF49899 63 267 5.39E-35 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain HVS_RS15350 faf8a224b0b1d01b8a77f73da6d076f7 295 Gene3D G3DSA:2.60.120.200 48 276 1.4E-34 T 29-03-2018 HVS_RS12540 e77cfbdbabee029e58df3f80b3991db7 215 Gene3D G3DSA:3.30.70.120 1 99 8.0E-8 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HVS_RS12540 e77cfbdbabee029e58df3f80b3991db7 215 Pfam PF00543 Nitrogen regulatory protein P-II 120 213 6.4E-9 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HVS_RS12540 e77cfbdbabee029e58df3f80b3991db7 215 SUPERFAMILY SSF54913 4 97 1.56E-9 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HVS_RS12540 e77cfbdbabee029e58df3f80b3991db7 215 SUPERFAMILY SSF54913 117 213 6.35E-21 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HVS_RS12540 e77cfbdbabee029e58df3f80b3991db7 215 Gene3D G3DSA:3.30.70.120 100 215 3.7E-21 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HVS_RS12540 e77cfbdbabee029e58df3f80b3991db7 215 SMART SM00938 120 213 4.1E-6 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 291 365 1.5E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 Gene3D G3DSA:1.25.40.10 263 650 2.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 Gene3D G3DSA:2.120.10.10 158 262 0.0015 T 29-03-2018 HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 SUPERFAMILY SSF48452 387 592 6.42E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 SUPERFAMILY SSF110296 32 165 1.57E-14 T 29-03-2018 HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 SUPERFAMILY SSF110296 199 266 1.57E-14 T 29-03-2018 HVS_RS06140 26f8476f5d059ffae2197d0943ac10e7 658 Gene3D G3DSA:2.120.10.10 8 157 5.7E-13 T 29-03-2018 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 Gene3D G3DSA:1.20.120.610 2 156 1.5E-28 T 29-03-2018 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 130 153 5.4E-6 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 53 77 5.4E-6 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 103 129 5.4E-6 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 SUPERFAMILY SSF81333 85 153 2.09E-9 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 Pfam PF00137 ATP synthase subunit C 14 72 3.4E-13 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 Pfam PF00137 ATP synthase subunit C 93 151 2.9E-11 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS01280 57bc2ed4fbb9817aa842d2676e6ee420 156 SUPERFAMILY SSF81333 10 76 3.66E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HVS_RS03290 268a90b9833327b6f67f98e56ed410e6 560 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 215 224 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 HVS_RS03290 268a90b9833327b6f67f98e56ed410e6 560 Gene3D G3DSA:3.20.20.80 34 441 1.0E-54 T 29-03-2018 HVS_RS03290 268a90b9833327b6f67f98e56ed410e6 560 Gene3D G3DSA:1.10.1330.10 494 560 1.8E-4 T 29-03-2018 HVS_RS03290 268a90b9833327b6f67f98e56ed410e6 560 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 50 414 2.8E-65 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 HVS_RS03290 268a90b9833327b6f67f98e56ed410e6 560 SUPERFAMILY SSF63446 497 559 2.22E-14 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS03290 268a90b9833327b6f67f98e56ed410e6 560 SUPERFAMILY SSF51445 36 441 2.46E-71 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 Gene3D G3DSA:1.20.1170.10 265 537 5.1E-4 T 29-03-2018 HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 Gene3D G3DSA:3.40.50.1390 1 168 4.8E-35 T 29-03-2018 HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 SUPERFAMILY SSF53041 3 158 7.72E-26 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 Pfam PF13408 Recombinase zinc beta ribbon domain 343 400 1.2E-5 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 Pfam PF00239 Resolvase, N terminal domain 5 157 5.8E-28 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 Pfam PF07508 Recombinase 201 314 5.5E-22 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 HVS_RS14925 a00b9f17cd96fbe641c144d6ec0268f2 545 SMART SM00857 4 158 7.4E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 SMART SM00388 48 114 3.5E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 161 253 2.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 Gene3D G3DSA:1.10.287.130 56 109 4.9E-10 T 29-03-2018 HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 SUPERFAMILY SSF55874 119 254 9.82E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 SUPERFAMILY SSF47384 44 112 1.18E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 SMART SM00387 160 263 2.1E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 Gene3D G3DSA:3.30.450.20 15 55 0.001 T 29-03-2018 HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 Pfam PF00512 His Kinase A (phospho-acceptor) domain 49 112 9.5E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS02160 495a5ee03a846eb7ef82563c88bf6f09 284 Gene3D G3DSA:3.30.565.10 122 283 2.9E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS11720 aebe4969f1e02de239c5b2b62bfe5e9d 251 Pfam PF07591 Pretoxin HINT domain 38 167 7.2E-31 T 29-03-2018 HVS_RS11720 aebe4969f1e02de239c5b2b62bfe5e9d 251 SUPERFAMILY SSF51294 32 165 1.57E-26 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS11720 aebe4969f1e02de239c5b2b62bfe5e9d 251 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 143 166 0.0023 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS11720 aebe4969f1e02de239c5b2b62bfe5e9d 251 Gene3D G3DSA:2.170.16.10 17 166 4.3E-39 T 29-03-2018 HVS_RS11720 aebe4969f1e02de239c5b2b62bfe5e9d 251 SMART SM00306 30 124 1.4E-11 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 SMART SM00729 93 317 0.0091 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 283 390 1.1E-18 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 Gene3D G3DSA:3.20.20.70 33 405 7.0E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 SUPERFAMILY SSF102114 54 358 4.58E-49 T 29-03-2018 HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 17 482 1.4E-156 T 29-03-2018 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 SMART SM00876 283 393 1.4E-21 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 HVS_RS12480 6ed58d3f9cd9d9902f83ea42af0094ec 482 Pfam PF04055 Radical SAM superfamily 99 223 1.4E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 SUPERFAMILY SSF51735 9 253 1.92E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 2.2E-51 T 29-03-2018 HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 9.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 9.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 9.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS04390 ff9ee6493dc61e701eb79b81ed2d226b 255 Gene3D G3DSA:3.40.50.720 5 255 2.0E-59 T 29-03-2018 HVS_RS15245 89ed8a581c720d41b9af1202af77f2f9 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 1.4E-113 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 HVS_RS15245 89ed8a581c720d41b9af1202af77f2f9 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 48.976 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 HVS_RS15245 89ed8a581c720d41b9af1202af77f2f9 257 SUPERFAMILY SSF51366 1 253 1.33E-83 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS15245 89ed8a581c720d41b9af1202af77f2f9 257 Pfam PF00977 Histidine biosynthesis protein 5 235 2.5E-87 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 HVS_RS15245 89ed8a581c720d41b9af1202af77f2f9 257 Gene3D G3DSA:3.20.20.70 4 248 2.7E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS10300 ef8d6bbc6da8483dd94f212a27bbee0a 242 SUPERFAMILY SSF55383 33 76 4.71E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10300 ef8d6bbc6da8483dd94f212a27bbee0a 242 Gene3D G3DSA:2.60.40.680 98 240 1.9E-24 T 29-03-2018 HVS_RS10300 ef8d6bbc6da8483dd94f212a27bbee0a 242 Pfam PF00963 Cohesin domain 105 218 3.6E-22 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS10300 ef8d6bbc6da8483dd94f212a27bbee0a 242 Gene3D G3DSA:3.30.457.10 24 72 6.9E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10300 ef8d6bbc6da8483dd94f212a27bbee0a 242 SUPERFAMILY SSF49384 103 237 3.4E-27 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS10300 ef8d6bbc6da8483dd94f212a27bbee0a 242 Pfam PF07833 Copper amine oxidase N-terminal domain 31 81 5.8E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13885 e68b6e52e7661f8a10c099bccea7f2cb 211 Gene3D G3DSA:3.40.190.10 57 196 1.4E-5 T 29-03-2018 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 SMART SM00962 101 302 2.9E-119 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 275 288 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 Pfam PF00448 SRP54-type protein, GTPase domain 101 301 1.5E-80 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 SMART SM00382 100 280 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 Gene3D G3DSA:3.40.50.300 102 303 4.2E-43 T 29-03-2018 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 Gene3D G3DSA:1.20.120.140 1 101 1.1E-26 T 29-03-2018 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 SUPERFAMILY SSF47364 1 82 9.94E-23 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 Pfam PF02881 SRP54-type protein, helical bundle domain 19 84 1.7E-15 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 SMART SM00963 7 88 5.1E-23 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 31 302 62.504 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 31 301 9.8E-114 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HVS_RS08785 03d6cde333798f25269f0c76704da4ec 306 SUPERFAMILY SSF52540 99 302 3.9E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07210 a6c93def92e9a99dd407e5fa88977dba 231 Pfam PF13398 Peptidase M50B-like 8 217 3.5E-27 T 29-03-2018 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 Pfam PF00171 Aldehyde dehydrogenase family 18 280 5.7E-16 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 410 37.202 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 Gene3D G3DSA:3.40.605.10 4 235 2.7E-46 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 Gene3D G3DSA:3.40.605.10 236 429 5.0E-44 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 PIRSF PIRSF000151 1 411 1.5E-168 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 SUPERFAMILY SSF53720 9 409 1.19E-116 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 317 339 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS05075 6b2bfe7db60b80c41bf3c94304e4fb36 431 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 400 4.3E-156 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 HVS_RS06465 d6a5f9dd71efa42ad890a0e38934b99e 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 3.6E-39 T 29-03-2018 IPR010375 Cyclic-di-AMP receptor HVS_RS06465 d6a5f9dd71efa42ad890a0e38934b99e 109 Gene3D G3DSA:3.30.70.120 1 109 3.7E-15 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HVS_RS06465 d6a5f9dd71efa42ad890a0e38934b99e 109 SUPERFAMILY SSF54913 2 108 1.39E-11 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HVS_RS08620 4c958d90cfd5d95105c4a7d16859dce4 406 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 402 3.4E-146 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS08620 4c958d90cfd5d95105c4a7d16859dce4 406 Pfam PF13742 OB-fold nucleic acid binding domain 12 107 8.3E-31 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 HVS_RS08620 4c958d90cfd5d95105c4a7d16859dce4 406 Pfam PF02601 Exonuclease VII, large subunit 339 400 7.3E-9 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 HVS_RS08620 4c958d90cfd5d95105c4a7d16859dce4 406 Pfam PF02601 Exonuclease VII, large subunit 130 340 1.2E-76 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 HVS_RS08620 4c958d90cfd5d95105c4a7d16859dce4 406 Gene3D G3DSA:2.40.50.140 7 108 1.4E-8 T 29-03-2018 HVS_RS08620 4c958d90cfd5d95105c4a7d16859dce4 406 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 9 403 27.626 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 PIRSF PIRSF002155 1 227 3.9E-79 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 Gene3D G3DSA:3.40.50.790 67 148 7.1E-37 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 227 3.4E-103 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 Gene3D G3DSA:3.30.190.20 149 228 1.9E-20 T 29-03-2018 HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 9.6E-57 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 229 43.863 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HVS_RS12970 bfb1afaca9c9b9f4dbe7d75715058df1 231 SUPERFAMILY SSF56808 5 225 2.22E-84 T 29-03-2018 IPR023674 Ribosomal protein L1-like HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 SUPERFAMILY SSF46894 127 227 1.39E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 SMART SM00862 150 226 1.2E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 Pfam PF00072 Response regulator receiver domain 5 114 2.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 Gene3D G3DSA:3.40.50.2300 2 123 9.7E-36 T 29-03-2018 HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 Gene3D G3DSA:1.10.10.10 124 231 3.3E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 SMART SM00448 3 113 4.8E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 SUPERFAMILY SSF52172 2 126 2.7E-42 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS15970 61537925463d65fa03667de7ddc3eda6 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 1.5E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS00170 897fc7dde496e9c02755b2040ffba93e 519 Gene3D G3DSA:3.10.350.10 469 518 8.3E-8 T 29-03-2018 HVS_RS00170 897fc7dde496e9c02755b2040ffba93e 519 Pfam PF12673 Domain of unknown function (DUF3794) 37 118 3.1E-15 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 HVS_RS00170 897fc7dde496e9c02755b2040ffba93e 519 Pfam PF12673 Domain of unknown function (DUF3794) 189 265 1.3E-14 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 HVS_RS00170 897fc7dde496e9c02755b2040ffba93e 519 Pfam PF12673 Domain of unknown function (DUF3794) 346 426 2.8E-13 T 29-03-2018 IPR024300 Domain of unknown function DUF3794 HVS_RS00170 897fc7dde496e9c02755b2040ffba93e 519 SUPERFAMILY SSF54106 472 516 3.01E-6 T 29-03-2018 IPR018392 LysM domain HVS_RS00170 897fc7dde496e9c02755b2040ffba93e 519 Pfam PF01476 LysM domain 477 516 3.1E-6 T 29-03-2018 IPR018392 LysM domain HVS_RS14400 a04d1d4d0430fff09bb81e2acac88606 258 PIRSF PIRSF017388 2 229 2.5E-41 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 HVS_RS14400 a04d1d4d0430fff09bb81e2acac88606 258 SUPERFAMILY SSF53474 8 226 1.33E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS14400 a04d1d4d0430fff09bb81e2acac88606 258 Gene3D G3DSA:3.40.50.1820 4 230 5.1E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS01775 b789915164cdda604a41b16c0c1046ed 361 SUPERFAMILY SSF47090 110 177 1.23E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01775 b789915164cdda604a41b16c0c1046ed 361 Gene3D G3DSA:1.10.101.10 105 185 1.7E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01775 b789915164cdda604a41b16c0c1046ed 361 Gene3D G3DSA:1.10.101.10 25 104 5.2E-22 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01775 b789915164cdda604a41b16c0c1046ed 361 SUPERFAMILY SSF47090 27 101 9.68E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01775 b789915164cdda604a41b16c0c1046ed 361 Pfam PF01471 Putative peptidoglycan binding domain 118 173 8.3E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS01775 b789915164cdda604a41b16c0c1046ed 361 Pfam PF01471 Putative peptidoglycan binding domain 38 92 9.4E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS15790 138e9281484c649209d567b3e95239ef 216 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site HVS_RS15790 138e9281484c649209d567b3e95239ef 216 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 8.5E-12 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal HVS_RS15790 138e9281484c649209d567b3e95239ef 216 Gene3D G3DSA:3.30.230.30 4 133 6.1E-43 T 29-03-2018 IPR001498 Impact, N-terminal HVS_RS15790 138e9281484c649209d567b3e95239ef 216 Pfam PF01205 Uncharacterized protein family UPF0029 19 121 3.8E-30 T 29-03-2018 IPR001498 Impact, N-terminal HVS_RS15790 138e9281484c649209d567b3e95239ef 216 SUPERFAMILY SSF54211 4 130 2.28E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS15790 138e9281484c649209d567b3e95239ef 216 SUPERFAMILY SSF54980 135 200 1.15E-7 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS15790 138e9281484c649209d567b3e95239ef 216 Gene3D G3DSA:3.30.70.240 135 198 1.6E-9 T 29-03-2018 HVS_RS15790 138e9281484c649209d567b3e95239ef 216 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 5 200 4.1E-54 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal HVS_RS12850 efff1ea2d5567938282a29d347cede03 229 SUPERFAMILY SSF53955 105 226 8.44E-49 T 29-03-2018 IPR023346 Lysozyme-like domain HVS_RS12850 efff1ea2d5567938282a29d347cede03 229 Gene3D G3DSA:1.10.530.10 58 229 1.4E-49 T 29-03-2018 HVS_RS12850 efff1ea2d5567938282a29d347cede03 229 Pfam PF01464 Transglycosylase SLT domain 105 212 7.0E-30 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 HVS_RS12850 efff1ea2d5567938282a29d347cede03 229 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 123 151 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 Gene3D G3DSA:3.40.50.150 161 375 3.3E-37 T 29-03-2018 HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 SUPERFAMILY SSF53335 143 218 2.5E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 SUPERFAMILY SSF53335 255 363 2.5E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 Pfam PF02926 THUMP domain 17 155 5.1E-14 T 29-03-2018 IPR004114 THUMP domain GO:0003723 HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 3.0E-53 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 SMART SM00981 58 155 8.2E-12 T 29-03-2018 IPR004114 THUMP domain GO:0003723 HVS_RS11960 87b1cb0406fd3b09ef454990747eda4a 377 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 SUPERFAMILY SSF52172 1 132 2.85E-33 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 Gene3D G3DSA:3.40.50.2300 1 142 2.7E-35 T 29-03-2018 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 Pfam PF00072 Response regulator receiver domain 4 116 5.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 SMART SM00421 150 207 3.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 206 2.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 SMART SM00448 2 115 5.0E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 Gene3D G3DSA:1.10.10.10 152 210 3.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 SUPERFAMILY SSF46894 152 209 4.76E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS05175 e424c2128d8ccaa8622525131c2ef120 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HVS_RS06870 288215df6bc5c3494f7e303cea4b004e 142 SUPERFAMILY SSF55729 14 126 5.82E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS06870 288215df6bc5c3494f7e303cea4b004e 142 Gene3D G3DSA:3.40.630.30 4 134 1.2E-16 T 29-03-2018 HVS_RS06870 288215df6bc5c3494f7e303cea4b004e 142 Pfam PF13673 Acetyltransferase (GNAT) domain 38 133 3.3E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS11735 99f1c4cac3ca499816b244a0413bde8a 229 Gene3D G3DSA:2.170.16.10 28 224 3.0E-39 T 29-03-2018 HVS_RS11735 99f1c4cac3ca499816b244a0413bde8a 229 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 143 167 9.2E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS11735 99f1c4cac3ca499816b244a0413bde8a 229 Pfam PF07591 Pretoxin HINT domain 38 167 2.6E-30 T 29-03-2018 HVS_RS11735 99f1c4cac3ca499816b244a0413bde8a 229 SMART SM00306 30 124 1.7E-11 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS11735 99f1c4cac3ca499816b244a0413bde8a 229 SUPERFAMILY SSF51294 32 165 5.49E-27 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS04585 34fb9c727d88aa3e0a0140c280656c97 283 Gene3D G3DSA:3.40.50.1240 15 166 7.1E-4 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS02420 fac06eb024fa18f637e0b687437d5c48 70 Pfam PF05979 Bacterial protein of unknown function (DUF896) 6 61 1.8E-24 T 29-03-2018 IPR009242 Protein of unknown function DUF896 HVS_RS02420 fac06eb024fa18f637e0b687437d5c48 70 Hamap MF_01103 UPF0291 protein . 2 61 14.067 T 29-03-2018 IPR009242 Protein of unknown function DUF896 HVS_RS02420 fac06eb024fa18f637e0b687437d5c48 70 Gene3D G3DSA:1.10.287.540 4 57 1.2E-23 T 29-03-2018 HVS_RS02420 fac06eb024fa18f637e0b687437d5c48 70 SUPERFAMILY SSF158221 2 43 2.22E-12 T 29-03-2018 HVS_RS12895 fe3d22641f53ab79b58af0a5512f67a4 236 Gene3D G3DSA:3.60.21.10 3 236 6.7E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS12895 fe3d22641f53ab79b58af0a5512f67a4 236 PIRSF PIRSF033094 1 236 1.8E-90 T 29-03-2018 IPR014578 Predicted phosphoesterase, CT488 type HVS_RS12895 fe3d22641f53ab79b58af0a5512f67a4 236 SUPERFAMILY SSF56300 3 206 7.03E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS12895 fe3d22641f53ab79b58af0a5512f67a4 236 Pfam PF00149 Calcineurin-like phosphoesterase 3 202 1.2E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HVS_RS04885 96d586de3ca854cbd3625d46793b296a 268 SUPERFAMILY SSF51658 2 263 4.45E-44 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS04885 96d586de3ca854cbd3625d46793b296a 268 Pfam PF01261 Xylose isomerase-like TIM barrel 21 212 5.2E-25 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS04885 96d586de3ca854cbd3625d46793b296a 268 Gene3D G3DSA:3.20.20.150 1 268 5.9E-44 T 29-03-2018 HVS_RS04130 b5d5c2f9c91f23a452651bb470ed82bf 192 Pfam PF02342 TerD domain 3 187 7.6E-74 T 29-03-2018 IPR003325 TerD domain GO:0006950 HVS_RS04130 b5d5c2f9c91f23a452651bb470ed82bf 192 Gene3D G3DSA:2.60.60.30 18 185 6.7E-56 T 29-03-2018 HVS_RS08940 152ab167acc2970a7259ef64db689841 260 Gene3D G3DSA:1.10.3720.10 52 250 2.0E-19 T 29-03-2018 HVS_RS08940 152ab167acc2970a7259ef64db689841 260 SUPERFAMILY SSF161098 58 243 1.11E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS08940 152ab167acc2970a7259ef64db689841 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 248 8.1E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 9 227 35.739 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 208 9.2E-25 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 Gene3D G3DSA:3.40.1010.10 7 117 1.2E-41 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 SUPERFAMILY SSF53790 7 225 7.85E-78 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 10 280 9.6E-81 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 Gene3D G3DSA:3.30.950.10 118 230 1.6E-37 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 PIRSF PIRSF005917 1 286 2.1E-99 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS14615 8c97d4e4b163bd6362cf86feff9d7107 286 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 87 98 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HVS_RS00250 b660be44c1848dd0a14dacd1ca1d6661 445 Gene3D G3DSA:3.40.190.10 181 368 1.2E-41 T 29-03-2018 HVS_RS00250 b660be44c1848dd0a14dacd1ca1d6661 445 Gene3D G3DSA:3.40.190.10 54 180 6.1E-23 T 29-03-2018 HVS_RS00250 b660be44c1848dd0a14dacd1ca1d6661 445 SUPERFAMILY SSF53850 53 444 4.56E-78 T 29-03-2018 HVS_RS00250 b660be44c1848dd0a14dacd1ca1d6661 445 SUPERFAMILY SSF53850 20 26 4.56E-78 T 29-03-2018 HVS_RS00250 b660be44c1848dd0a14dacd1ca1d6661 445 Pfam PF01547 Bacterial extracellular solute-binding protein 73 356 2.9E-38 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 HVS_RS15845 32b4429cd73f1507ecbe088ab4e4aad4 436 SUPERFAMILY SSF102114 43 187 6.15E-13 T 29-03-2018 HVS_RS15845 32b4429cd73f1507ecbe088ab4e4aad4 436 Gene3D G3DSA:3.20.20.70 44 309 1.9E-32 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS15845 32b4429cd73f1507ecbe088ab4e4aad4 436 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 3 416 7.2E-201 T 29-03-2018 IPR023874 DNA modification/repair radical SAM protein, putative HVS_RS15845 32b4429cd73f1507ecbe088ab4e4aad4 436 SUPERFAMILY SSF47781 301 379 4.0E-13 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS15845 32b4429cd73f1507ecbe088ab4e4aad4 436 Gene3D G3DSA:1.10.150.320 310 373 4.7E-4 T 29-03-2018 HVS_RS07695 d268cf86a5b2fde48627b7423172fe66 186 SUPERFAMILY SSF56784 29 158 1.52E-22 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07695 d268cf86a5b2fde48627b7423172fe66 186 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 45 155 6.1E-16 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 HVS_RS07695 d268cf86a5b2fde48627b7423172fe66 186 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 153 2.6E-11 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07695 d268cf86a5b2fde48627b7423172fe66 186 Gene3D G3DSA:3.40.50.1000 23 177 4.0E-20 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07695 d268cf86a5b2fde48627b7423172fe66 186 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 22 168 1.4E-37 T 29-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like HVS_RS05405 5b61cfeeea9099bc0766dab33ee00ead 94 Pfam PF03776 Septum formation topological specificity factor MinE 15 87 5.3E-25 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 HVS_RS05405 5b61cfeeea9099bc0766dab33ee00ead 94 Hamap MF_00262 Cell division topological specificity factor [minE]. 1 91 16.043 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 HVS_RS05405 5b61cfeeea9099bc0766dab33ee00ead 94 SUPERFAMILY SSF55229 31 90 1.44E-10 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 HVS_RS05405 5b61cfeeea9099bc0766dab33ee00ead 94 Gene3D G3DSA:3.30.1070.10 3 88 8.9E-29 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 HVS_RS05405 5b61cfeeea9099bc0766dab33ee00ead 94 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 7 87 3.0E-20 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 HVS_RS08465 3fd7d61ec0d9c0815f24de7909e60d9a 107 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 78 2.2E-12 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS08465 3fd7d61ec0d9c0815f24de7909e60d9a 107 SUPERFAMILY SSF56601 1 106 3.13E-17 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS08465 3fd7d61ec0d9c0815f24de7909e60d9a 107 Gene3D G3DSA:3.40.710.10 28 98 6.0E-12 T 29-03-2018 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 SMART SM00382 345 536 6.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 SMART SM00382 31 235 2.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 Pfam PF00005 ABC transporter 23 178 1.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 Pfam PF00005 ABC transporter 337 485 1.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 ProSitePatterns PS00211 ABC transporters family signature. 459 473 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 Gene3D G3DSA:3.40.50.300 2 312 1.2E-66 T 29-03-2018 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 SUPERFAMILY SSF52540 317 546 9.61E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 SUPERFAMILY SSF52540 3 248 1.5E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 308 2.1E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 Gene3D G3DSA:3.40.50.300 315 550 9.0E-59 T 29-03-2018 HVS_RS13935 b6d9e409d50839c689277617fdbd8eea 552 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 290 1.9E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 169 25.292 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 Gene3D G3DSA:2.40.30.60 2 94 2.2E-25 T 29-03-2018 IPR002676 RimM protein GO:0006364 HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 SUPERFAMILY SSF50447 4 90 5.65E-22 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 Pfam PF05239 PRC-barrel domain 96 169 1.0E-12 T 29-03-2018 IPR027275 PRC-barrel domain HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 169 4.4E-50 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 SUPERFAMILY SSF50346 99 169 1.57E-19 T 29-03-2018 IPR011033 PRC-barrel-like HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 Gene3D G3DSA:2.30.30.240 99 169 3.4E-21 T 29-03-2018 HVS_RS08365 952464a9a6fb73b60c292a3eb944b2b1 174 Pfam PF01782 RimM N-terminal domain 6 90 3.8E-24 T 29-03-2018 IPR002676 RimM protein GO:0006364 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 421 8.0E-110 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 Gene3D G3DSA:3.40.1190.10 1 291 1.1E-76 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 42 65 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 Gene3D G3DSA:3.90.190.20 292 424 2.3E-23 T 29-03-2018 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 Pfam PF02875 Mur ligase family, glutamate ligase domain 290 355 3.7E-8 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 Pfam PF08245 Mur ligase middle domain 44 263 1.1E-13 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 PIRSF PIRSF001563 1 424 1.6E-140 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 SUPERFAMILY SSF53244 292 423 7.17E-27 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 139 154 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 HVS_RS11300 c02398e2ae1d70747c29f285a17dc9e5 424 SUPERFAMILY SSF53623 1 290 9.39E-85 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 HVS_RS12060 d899b2777a66b0156b2c51415197dbb7 154 SUPERFAMILY SSF103039 1 143 9.81E-37 T 29-03-2018 IPR028976 CheC-like domain HVS_RS12060 d899b2777a66b0156b2c51415197dbb7 154 Gene3D G3DSA:3.40.1550.10 1 154 1.0E-36 T 29-03-2018 IPR028976 CheC-like domain HVS_RS12060 d899b2777a66b0156b2c51415197dbb7 154 Pfam PF13690 Chemotaxis phosphatase CheX 43 138 1.4E-20 T 29-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain HVS_RS14590 4e7eb7e343536d8575daa8053ab412b8 257 PIRSF PIRSF005902 1 256 1.0E-87 T 29-03-2018 IPR001130 TatD family GO:0016788 HVS_RS14590 4e7eb7e343536d8575daa8053ab412b8 257 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HVS_RS14590 4e7eb7e343536d8575daa8053ab412b8 257 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 3.2E-92 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 HVS_RS14590 4e7eb7e343536d8575daa8053ab412b8 257 Gene3D G3DSA:3.20.20.140 1 257 1.8E-95 T 29-03-2018 HVS_RS14590 4e7eb7e343536d8575daa8053ab412b8 257 SUPERFAMILY SSF51556 2 254 9.34E-96 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS14590 4e7eb7e343536d8575daa8053ab412b8 257 Pfam PF01026 TatD related DNase 3 253 5.0E-88 T 29-03-2018 IPR001130 TatD family GO:0016788 HVS_RS08445 bb7ef77632cae67b0c53dbccfa74594a 290 SUPERFAMILY SSF53271 71 209 1.8E-9 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS08445 bb7ef77632cae67b0c53dbccfa74594a 290 Gene3D G3DSA:3.40.50.2020 6 222 3.6E-16 T 29-03-2018 HVS_RS00050 f92a42c84ef4dcb7151007a48e8817f5 254 Pfam PF14853 Fis1 C-terminal tetratricopeptide repeat 200 251 1.9E-7 T 29-03-2018 IPR028061 Fis1, C-terminal tetratricopeptide repeat HVS_RS00050 f92a42c84ef4dcb7151007a48e8817f5 254 Gene3D G3DSA:1.25.40.10 63 246 1.9E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS00050 f92a42c84ef4dcb7151007a48e8817f5 254 SUPERFAMILY SSF48452 156 235 1.02E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS03490 0d00a6e98c8ef31f917230abd7c8b429 269 SUPERFAMILY SSF55383 57 141 1.57E-24 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03490 0d00a6e98c8ef31f917230abd7c8b429 269 Gene3D G3DSA:3.30.457.10 24 65 1.7E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03490 0d00a6e98c8ef31f917230abd7c8b429 269 Gene3D G3DSA:3.30.457.10 66 129 7.2E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03490 0d00a6e98c8ef31f917230abd7c8b429 269 Gene3D G3DSA:3.30.457.10 130 263 3.5E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03490 0d00a6e98c8ef31f917230abd7c8b429 269 Pfam PF07833 Copper amine oxidase N-terminal domain 54 146 5.3E-32 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03515 116f6df40c300354928c239e80ffa7f9 99 Pfam PF06013 Proteins of 100 residues with WXG 4 87 3.7E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03515 116f6df40c300354928c239e80ffa7f9 99 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 6.6E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03515 116f6df40c300354928c239e80ffa7f9 99 SUPERFAMILY SSF140453 3 94 1.31E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03515 116f6df40c300354928c239e80ffa7f9 99 Gene3D G3DSA:1.10.287.850 1 93 1.8E-17 T 29-03-2018 HVS_RS03410 116f6df40c300354928c239e80ffa7f9 99 Pfam PF06013 Proteins of 100 residues with WXG 4 87 3.7E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03410 116f6df40c300354928c239e80ffa7f9 99 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 6.6E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03410 116f6df40c300354928c239e80ffa7f9 99 SUPERFAMILY SSF140453 3 94 1.31E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03410 116f6df40c300354928c239e80ffa7f9 99 Gene3D G3DSA:1.10.287.850 1 93 1.8E-17 T 29-03-2018 HVS_RS03540 116f6df40c300354928c239e80ffa7f9 99 Pfam PF06013 Proteins of 100 residues with WXG 4 87 3.7E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03540 116f6df40c300354928c239e80ffa7f9 99 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 6.6E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03540 116f6df40c300354928c239e80ffa7f9 99 SUPERFAMILY SSF140453 3 94 1.31E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS03540 116f6df40c300354928c239e80ffa7f9 99 Gene3D G3DSA:1.10.287.850 1 93 1.8E-17 T 29-03-2018 HVS_RS15990 2d0ca83ee9654564c1215e3b4672f097 56 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 9 52 1.0E-7 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HVS_RS15990 2d0ca83ee9654564c1215e3b4672f097 56 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 12 21 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 Pfam PF03129 Anticodon binding domain 329 417 3.1E-16 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 PIRSF PIRSF001549 1 419 2.8E-131 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 Gene3D G3DSA:3.40.50.800 324 427 3.1E-21 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 Pfam PF13393 Histidyl-tRNA synthetase 8 310 3.8E-50 T 29-03-2018 HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 SUPERFAMILY SSF55681 4 318 4.18E-99 T 29-03-2018 HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 SUPERFAMILY SSF52954 326 417 1.25E-25 T 29-03-2018 IPR004154 Anticodon-binding HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 4.5E-161 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 417 34.101 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 HVS_RS11160 4c55b49e19e7f93cdd778151b5c92c56 435 Gene3D G3DSA:3.30.930.10 1 322 3.7E-74 T 29-03-2018 HVS_RS11995 649938d23fa37496329799a29691a70b 336 SUPERFAMILY SSF55347 150 313 8.04E-83 T 29-03-2018 HVS_RS11995 649938d23fa37496329799a29691a70b 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 2.1E-39 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 SMART SM00846 3 151 4.8E-98 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 SUPERFAMILY SSF51735 3 172 1.52E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS11995 649938d23fa37496329799a29691a70b 336 Gene3D G3DSA:3.40.50.720 1 160 3.8E-84 T 29-03-2018 HVS_RS11995 649938d23fa37496329799a29691a70b 336 Gene3D G3DSA:3.30.360.10 161 315 5.0E-85 T 29-03-2018 HVS_RS11995 649938d23fa37496329799a29691a70b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 2.9E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.9E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 2.9E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.9E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.9E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 PIRSF PIRSF000149 1 335 7.0E-136 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.8E-139 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS11995 649938d23fa37496329799a29691a70b 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 1.4E-73 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 1.0E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 Pfam PF00072 Response regulator receiver domain 7 115 1.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 SUPERFAMILY SSF52172 4 184 1.37E-38 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 Gene3D G3DSA:3.40.50.2300 2 128 3.4E-35 T 29-03-2018 HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 SMART SM00448 5 115 4.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 SMART SM00862 152 228 8.8E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS03070 99479b5d22dbe1aee2dd3e0a21ee1630 230 Gene3D G3DSA:1.10.10.10 129 230 1.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10700 b09228edbfe0ffa92ffab46f89e6be42 248 Pfam PF07833 Copper amine oxidase N-terminal domain 23 77 7.8E-12 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10700 b09228edbfe0ffa92ffab46f89e6be42 248 Pfam PF07833 Copper amine oxidase N-terminal domain 48 140 3.2E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10700 b09228edbfe0ffa92ffab46f89e6be42 248 Gene3D G3DSA:3.30.457.10 60 122 1.3E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10700 b09228edbfe0ffa92ffab46f89e6be42 248 Gene3D G3DSA:3.30.457.10 18 59 2.6E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10700 b09228edbfe0ffa92ffab46f89e6be42 248 Gene3D G3DSA:3.30.457.10 123 205 3.5E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10700 b09228edbfe0ffa92ffab46f89e6be42 248 SUPERFAMILY SSF55383 51 135 5.95E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 SUPERFAMILY SSF46604 87 134 4.71E-6 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 SUPERFAMILY SSF51344 2 85 1.27E-18 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 3.5E-27 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 70 8.0E-5 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 Gene3D G3DSA:1.20.5.440 90 132 1.4E-6 T 29-03-2018 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 Gene3D G3DSA:2.60.15.10 1 89 2.7E-22 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 1.2E-18 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 17.228 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS03660 52d5be2f5a32f47c2e7dd04951ef4ad4 143 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 131 5.0E-8 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 HVS_RS13850 6a5883f3e763bed59fd9f51fba783513 75 Gene3D G3DSA:1.20.1260.10 1 66 5.5E-5 T 29-03-2018 IPR012347 Ferritin-related HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 PIRSF PIRSF000148 3 330 2.5E-129 T 29-03-2018 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 SMART SM00859 5 121 7.1E-45 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 313 3.4E-48 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 SUPERFAMILY SSF51735 5 157 7.45E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 328 1.9E-142 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 Gene3D G3DSA:3.40.50.720 1 141 2.6E-33 T 29-03-2018 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 119 6.4E-32 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 327 37.019 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 Gene3D G3DSA:3.30.360.10 142 309 1.4E-67 T 29-03-2018 HVS_RS08995 633cfeaaabd56f6990acddde86f5ce9a 336 SUPERFAMILY SSF55347 129 314 8.64E-74 T 29-03-2018 HVS_RS08745 c89270beb609631911faffa90f8a103b 370 Pfam PF00990 Diguanylate cyclase, GGDEF domain 189 348 4.1E-48 T 29-03-2018 IPR000160 GGDEF domain HVS_RS08745 c89270beb609631911faffa90f8a103b 370 SMART SM00267 179 352 4.1E-53 T 29-03-2018 IPR000160 GGDEF domain HVS_RS08745 c89270beb609631911faffa90f8a103b 370 SUPERFAMILY SSF55073 194 353 3.37E-48 T 29-03-2018 IPR029787 Nucleotide cyclase HVS_RS08745 c89270beb609631911faffa90f8a103b 370 Gene3D G3DSA:3.30.70.270 186 366 3.8E-54 T 29-03-2018 HVS_RS08745 c89270beb609631911faffa90f8a103b 370 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 351 2.0E-49 T 29-03-2018 IPR000160 GGDEF domain HVS_RS15755 8ad2d382bbb0cca70fb927616f2eaaa9 302 Pfam PF08812 YtxC-like family 69 281 7.1E-74 T 29-03-2018 IPR014199 Sporulation protein YtxC HVS_RS15755 8ad2d382bbb0cca70fb927616f2eaaa9 302 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 41 282 4.1E-67 T 29-03-2018 IPR014199 Sporulation protein YtxC HVS_RS00095 3f9130da92840109721e4df3e44e0cb0 159 Gene3D G3DSA:3.60.21.10 1 159 4.2E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS00095 3f9130da92840109721e4df3e44e0cb0 159 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 149 2.2E-33 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 HVS_RS00095 3f9130da92840109721e4df3e44e0cb0 159 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 151 6.9E-29 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 HVS_RS00095 3f9130da92840109721e4df3e44e0cb0 159 SUPERFAMILY SSF56300 1 158 7.06E-40 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS15050 2b4ec978e88e7156bad75a9289048f82 60 Gene3D G3DSA:3.30.1390.20 4 59 4.2E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HVS_RS15050 2b4ec978e88e7156bad75a9289048f82 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 59 5.2E-19 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15050 2b4ec978e88e7156bad75a9289048f82 60 SUPERFAMILY SSF55129 2 60 2.49E-16 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HVS_RS15050 2b4ec978e88e7156bad75a9289048f82 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 59 14.903 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15050 2b4ec978e88e7156bad75a9289048f82 60 PIRSF PIRSF002211 1 60 3.0E-21 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS15050 2b4ec978e88e7156bad75a9289048f82 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 55 4.6E-17 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HVS_RS09180 58d781ff5c227cc433eb771900353931 309 Gene3D G3DSA:3.20.20.140 232 309 2.4E-25 T 29-03-2018 HVS_RS09180 58d781ff5c227cc433eb771900353931 309 Gene3D G3DSA:3.20.20.140 1 231 4.7E-85 T 29-03-2018 HVS_RS09180 58d781ff5c227cc433eb771900353931 309 SUPERFAMILY SSF51556 1 309 4.42E-95 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS09180 58d781ff5c227cc433eb771900353931 309 ProSitePatterns PS00869 Renal dipeptidase active site. 101 123 - T 29-03-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 HVS_RS09180 58d781ff5c227cc433eb771900353931 309 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 1.5E-109 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 Gene3D G3DSA:3.40.50.300 190 382 2.0E-24 T 29-03-2018 HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 SUPERFAMILY SSF52540 193 384 2.55E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 SMART SM00382 194 340 1.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 282 2.5E-68 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 SMART SM00962 195 386 5.8E-67 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 Gene3D G3DSA:3.30.930.10 97 174 0.0017 T 29-03-2018 HVS_RS10155 3292dd177865fbeb1eb2d676f72923cb 388 Pfam PF00448 SRP54-type protein, GTPase domain 195 385 4.7E-43 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 HVS_RS16045 1e751b398f24003486f66130fc5b8aa5 243 SUPERFAMILY SSF55383 1 50 4.18E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16045 1e751b398f24003486f66130fc5b8aa5 243 Pfam PF07833 Copper amine oxidase N-terminal domain 1 56 3.0E-15 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16045 1e751b398f24003486f66130fc5b8aa5 243 Gene3D G3DSA:3.30.457.10 1 38 1.4E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16045 1e751b398f24003486f66130fc5b8aa5 243 Gene3D G3DSA:3.30.457.10 39 134 2.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01375 05b63349fac5ce91bb3d6946a40a7b02 166 SUPERFAMILY SSF140566 6 137 3.66E-18 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HVS_RS01375 05b63349fac5ce91bb3d6946a40a7b02 166 Gene3D G3DSA:1.20.58.300 4 138 1.0E-23 T 29-03-2018 HVS_RS01375 05b63349fac5ce91bb3d6946a40a7b02 166 Pfam PF05130 FlgN protein 4 153 3.0E-27 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 Gene3D G3DSA:3.30.310.40 14 99 1.9E-11 T 29-03-2018 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 Gene3D G3DSA:1.10.1670.10 239 292 8.7E-16 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 SUPERFAMILY SSF48150 116 288 1.46E-35 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 SMART SM00478 126 288 4.9E-13 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 Gene3D G3DSA:1.10.340.30 116 236 6.1E-30 T 29-03-2018 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 122 267 1.0E-11 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 21 121 5.7E-23 T 29-03-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 HVS_RS15740 9513a9503d2bd456e8d2043e377a44ef 294 SUPERFAMILY SSF55945 14 115 8.0E-22 T 29-03-2018 HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 SUPERFAMILY SSF50494 372 430 2.84E-5 T 29-03-2018 IPR009003 Peptidase S1, PA clan HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 Gene3D G3DSA:2.40.10.10 297 433 1.4E-4 T 29-03-2018 HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 Gene3D G3DSA:2.30.42.10 128 230 2.1E-13 T 29-03-2018 HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 SMART SM00228 124 199 0.006 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 Pfam PF05580 SpoIVB peptidase S55 216 424 2.7E-87 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 SUPERFAMILY SSF50156 128 206 9.73E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 HVS_RS09705 f0f2985a5d4a8874c0448bae35e03446 442 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 10 428 9.9E-136 T 29-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B HVS_RS07075 083ba094524f489ad60f597f516e4869 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HVS_RS07075 083ba094524f489ad60f597f516e4869 219 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 2.2E-90 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HVS_RS07075 083ba094524f489ad60f597f516e4869 219 Gene3D G3DSA:3.20.20.70 1 217 2.4E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS07075 083ba094524f489ad60f597f516e4869 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 5.2E-81 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HVS_RS07075 083ba094524f489ad60f597f516e4869 219 PIRSF PIRSF001461 1 219 1.2E-93 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 HVS_RS07075 083ba094524f489ad60f597f516e4869 219 SUPERFAMILY SSF51366 2 214 3.04E-72 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 Pfam PF08323 Starch synthase catalytic domain 8 245 2.5E-83 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 8 482 3.5E-179 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 Hamap MF_00484 Glycogen synthase [glgA]. 7 483 44.43 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 SUPERFAMILY SSF53756 8 485 4.54E-129 T 29-03-2018 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 Pfam PF00534 Glycosyl transferases group 1 298 446 3.2E-14 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 Gene3D G3DSA:3.40.50.2000 271 479 9.1E-39 T 29-03-2018 HVS_RS10900 746654666c734ea80a04f2bac5f92760 488 Gene3D G3DSA:3.40.50.2000 1 270 1.7E-5 T 29-03-2018 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 Gene3D G3DSA:3.40.50.150 263 646 1.2E-35 T 29-03-2018 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 261 277 6.2E-8 T 29-03-2018 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 508 520 6.2E-8 T 29-03-2018 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 327 341 6.2E-8 T 29-03-2018 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 Gene3D G3DSA:3.90.220.10 667 854 1.5E-22 T 29-03-2018 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 511 517 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 SUPERFAMILY SSF53335 506 635 2.43E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 SUPERFAMILY SSF53335 424 442 2.43E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 SUPERFAMILY SSF53335 323 387 2.43E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 SUPERFAMILY SSF53335 69 280 2.43E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS02810 e8f703e94aab2b4789cf1570724763c3 1220 Pfam PF02384 N-6 DNA Methylase 501 616 5.1E-8 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HVS_RS12030 531cc242843458faf80dca75eb3c966d 86 SUPERFAMILY SSF47336 1 54 1.73E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS12030 531cc242843458faf80dca75eb3c966d 86 Pfam PF00550 Phosphopantetheine attachment site 11 57 1.2E-5 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain HVS_RS12030 531cc242843458faf80dca75eb3c966d 86 Gene3D G3DSA:1.10.1200.10 4 80 2.3E-11 T 29-03-2018 HVS_RS02195 cdf52916bb02c7a87b9a8012a6edbc18 384 Pfam PF10646 Sporulation and spore germination 82 193 9.9E-27 T 29-03-2018 IPR019606 GerMN domain HVS_RS02195 cdf52916bb02c7a87b9a8012a6edbc18 384 SMART SM00909 109 197 4.2E-31 T 29-03-2018 IPR019606 GerMN domain HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 SUPERFAMILY SSF54980 395 468 1.47E-13 T 29-03-2018 IPR035647 EF-G domain III/V-like HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 SUPERFAMILY SSF52540 11 278 1.11E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 149 7.7E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Gene3D G3DSA:3.40.50.300 7 271 2.3E-36 T 29-03-2018 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 5 530 49.869 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Gene3D G3DSA:2.40.30.10 272 385 1.3E-19 T 29-03-2018 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 SUPERFAMILY SSF50447 262 389 9.34E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Pfam PF16658 Class II release factor RF3, C-terminal domain 389 517 1.2E-46 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Pfam PF00009 Elongation factor Tu GTP binding domain 16 278 2.2E-50 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Gene3D G3DSA:3.30.70.870 391 468 1.0E-10 T 29-03-2018 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 PRINTS PR00315 GTP-binding elongation factor signature 86 96 3.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 PRINTS PR00315 GTP-binding elongation factor signature 66 74 3.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 PRINTS PR00315 GTP-binding elongation factor signature 102 113 3.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 PRINTS PR00315 GTP-binding elongation factor signature 138 147 3.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 Pfam PF03144 Elongation factor Tu domain 2 315 380 2.9E-7 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 HVS_RS02710 09923955ec2059a8fdb20fc0d424e1bc 533 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 8 531 1.2E-207 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 HVS_RS02360 a8a418ce514eff255250eb65614cb6f9 665 Gene3D G3DSA:3.30.1380.10 424 662 1.5E-11 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02360 a8a418ce514eff255250eb65614cb6f9 665 SUPERFAMILY SSF55166 532 664 4.45E-15 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS02360 a8a418ce514eff255250eb65614cb6f9 665 Pfam PF00395 S-layer homology domain 257 298 9.9E-15 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS02360 a8a418ce514eff255250eb65614cb6f9 665 Pfam PF00395 S-layer homology domain 396 426 3.5E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS02360 a8a418ce514eff255250eb65614cb6f9 665 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 584 661 9.7E-15 T 29-03-2018 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 SMART SM00448 3 116 1.4E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 SUPERFAMILY SSF46689 437 488 1.12E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 Pfam PF12833 Helix-turn-helix domain 460 538 1.1E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 Gene3D G3DSA:3.40.50.2300 3 128 1.2E-26 T 29-03-2018 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 Gene3D G3DSA:2.60.120.10 129 495 3.9E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 SUPERFAMILY SSF52172 4 126 8.25E-28 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 SMART SM00342 454 537 3.4E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 Gene3D G3DSA:1.10.10.60 496 544 2.5E-13 T 29-03-2018 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 SUPERFAMILY SSF46689 491 541 1.3E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS12130 66b8fba4412e09070b154f3a8e78a5b0 544 Pfam PF00072 Response regulator receiver domain 4 116 1.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS01865 79bd998bb8c2eafd8642d6e06f97eed4 275 SMART SM00943 9 184 3.2E-55 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS01865 79bd998bb8c2eafd8642d6e06f97eed4 275 SUPERFAMILY SSF56747 39 191 4.18E-25 T 29-03-2018 HVS_RS01865 79bd998bb8c2eafd8642d6e06f97eed4 275 SMART SM00942 201 267 1.2E-21 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS01865 79bd998bb8c2eafd8642d6e06f97eed4 275 Pfam PF08708 Primase C terminal 1 (PriCT-1) 203 267 1.5E-17 T 29-03-2018 IPR014820 Primase, C-terminal 1 HVS_RS01865 79bd998bb8c2eafd8642d6e06f97eed4 275 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 10 177 2.8E-41 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal HVS_RS05635 2489b0e3b76ecea0327b7bccf58e1d3c 267 Gene3D G3DSA:2.140.10.30 162 267 2.5E-5 T 29-03-2018 HVS_RS05635 2489b0e3b76ecea0327b7bccf58e1d3c 267 Pfam PF16472 Domain of unknown function (DUF5050) 4 250 7.7E-27 T 29-03-2018 IPR032485 Domain of unknown function DUF5050 HVS_RS05635 2489b0e3b76ecea0327b7bccf58e1d3c 267 SUPERFAMILY SSF63825 14 224 1.57E-15 T 29-03-2018 HVS_RS05635 2489b0e3b76ecea0327b7bccf58e1d3c 267 Gene3D G3DSA:2.120.10.60 5 156 5.1E-5 T 29-03-2018 HVS_RS04040 2768a257e29faefb57cc25fe768d2986 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 7.2E-90 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS00435 9b6736092f2691c0105eb52201953769 172 SMART SM00471 25 148 2.6E-5 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS00435 9b6736092f2691c0105eb52201953769 172 SUPERFAMILY SSF109604 23 143 8.3E-28 T 29-03-2018 HVS_RS00435 9b6736092f2691c0105eb52201953769 172 Gene3D G3DSA:1.10.3210.10 3 170 2.6E-21 T 29-03-2018 HVS_RS00435 9b6736092f2691c0105eb52201953769 172 Pfam PF01966 HD domain 31 137 2.4E-17 T 29-03-2018 IPR006674 HD domain HVS_RS00435 9b6736092f2691c0105eb52201953769 172 TIGRFAM TIGR00277 HDIG: HDIG domain 30 95 2.9E-12 T 29-03-2018 IPR006675 HDIG domain HVS_RS11000 744c25e6019c6f7c63944baedf1abeda 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.1E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS15355 744c25e6019c6f7c63944baedf1abeda 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 1.1E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS05135 eb978b3287f8a78746f3dfbfb9bc3d9d 289 Gene3D G3DSA:2.60.40.1180 9 57 1.7E-28 T 29-03-2018 HVS_RS05135 eb978b3287f8a78746f3dfbfb9bc3d9d 289 Gene3D G3DSA:3.40.50.150 58 265 1.1E-35 T 29-03-2018 HVS_RS05135 eb978b3287f8a78746f3dfbfb9bc3d9d 289 SUPERFAMILY SSF53335 3 255 1.21E-60 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS05135 eb978b3287f8a78746f3dfbfb9bc3d9d 289 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 54 201 7.0E-17 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 SUPERFAMILY SSF49265 294 465 5.84E-23 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 Gene3D G3DSA:2.60.40.10 382 467 3.8E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 Gene3D G3DSA:2.60.40.10 292 380 1.8E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 SUPERFAMILY SSF49265 217 331 1.45E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 Gene3D G3DSA:2.60.40.10 570 680 0.021 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 Gene3D G3DSA:2.60.40.10 483 569 0.11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 Gene3D G3DSA:2.60.40.10 202 291 6.7E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 787 830 3.0E-6 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 SMART SM00060 387 461 1.0E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 SMART SM00060 581 655 52.0 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 SMART SM00060 209 283 100.0 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS09360 bfa3476c0162bae2288cb4eae7dfad18 1040 SMART SM00060 296 370 1.3E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 Pfam PF01471 Putative peptidoglycan binding domain 125 187 6.0E-5 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 315 444 3.9E-14 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 Gene3D G3DSA:1.10.101.10 112 194 1.1E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 SMART SM00047 302 456 3.4E-28 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 Gene3D G3DSA:1.10.530.10 299 448 7.2E-25 T 29-03-2018 HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 Pfam PF05257 CHAP domain 512 611 1.0E-8 T 29-03-2018 IPR007921 CHAP domain HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 Gene3D G3DSA:3.90.1720.10 476 627 2.0E-7 T 29-03-2018 HVS_RS03455 0a18f2fefaa8f21ede861f721a5f9ca6 654 SUPERFAMILY SSF47090 111 189 1.8E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS08980 6762fb626a34dbdbc992c0403c27319e 158 Pfam PF13840 ACT domain 95 150 5.5E-11 T 29-03-2018 IPR027795 GATS-like ACT domain HVS_RS08980 6762fb626a34dbdbc992c0403c27319e 158 SUPERFAMILY SSF55021 89 158 8.44E-18 T 29-03-2018 HVS_RS08980 6762fb626a34dbdbc992c0403c27319e 158 Gene3D G3DSA:3.30.70.260 87 158 3.4E-17 T 29-03-2018 HVS_RS08980 6762fb626a34dbdbc992c0403c27319e 158 SUPERFAMILY SSF55021 3 79 4.2E-15 T 29-03-2018 HVS_RS08980 6762fb626a34dbdbc992c0403c27319e 158 Gene3D G3DSA:3.30.70.260 1 85 2.9E-16 T 29-03-2018 HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 166 201 3.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 222 252 7.1E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 128 164 1.9E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 243 282 7.2E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 65 101 3.0E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 19 59 9.4E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 103 144 1.2E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 124 161 1.1E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 82 118 8.7E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 166 203 9.1E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 226 259 8.1E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 263 299 4.6E-10 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 206 236 1.4E-4 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 243 278 1.9E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 149 181 5.2E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 SUPERFAMILY SSF69304 12 177 1.05E-5 T 29-03-2018 HVS_RS14780 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 543 622 1.7E-19 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 166 201 3.2E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 222 252 7.1E-5 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 128 164 1.9E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 243 282 7.2E-9 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 65 101 3.0E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 19 59 9.4E-6 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 103 144 1.2E-7 T 29-03-2018 IPR006530 YD repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 124 161 1.1E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 82 118 8.7E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 166 203 9.1E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 226 259 8.1E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 263 299 4.6E-10 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 206 236 1.4E-4 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 243 278 1.9E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 Pfam PF05593 RHS Repeat 149 181 5.2E-6 T 29-03-2018 IPR031325 RHS repeat HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 SUPERFAMILY SSF69304 12 177 1.05E-5 T 29-03-2018 HVS_RS06045 2b34df8b1a94273731079d5b18422fde 832 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 543 622 1.7E-19 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS02550 b2b57171c688dd37ff9ae0fec56c0fa9 350 Pfam PF02424 ApbE family 44 320 2.6E-86 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 HVS_RS02550 b2b57171c688dd37ff9ae0fec56c0fa9 350 SUPERFAMILY SSF143631 38 339 1.4E-98 T 29-03-2018 IPR003374 ApbE-like domain HVS_RS02550 b2b57171c688dd37ff9ae0fec56c0fa9 350 Gene3D G3DSA:3.10.520.10 31 342 2.2E-58 T 29-03-2018 HVS_RS02550 b2b57171c688dd37ff9ae0fec56c0fa9 350 PIRSF PIRSF006268 5 346 1.5E-109 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 HVS_RS10305 6b8d334c315b2cfcc2f826b3d9851ebc 151 Pfam PF03477 ATP cone domain 50 136 3.4E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 HVS_RS10305 6b8d334c315b2cfcc2f826b3d9851ebc 151 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 151 86.218 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HVS_RS10305 6b8d334c315b2cfcc2f826b3d9851ebc 151 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 3.6E-64 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HVS_RS13180 9b280653e5c35d69d77ed43f79ad5c6b 143 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 10 137 7.3E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component HVS_RS13180 9b280653e5c35d69d77ed43f79ad5c6b 143 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 11 107 9.1E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component HVS_RS09310 089504c50d3269d5793f9106791fec73 127 PIRSF PIRSF006246 1 127 2.5E-56 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HVS_RS09310 089504c50d3269d5793f9106791fec73 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 72.082 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HVS_RS09310 089504c50d3269d5793f9106791fec73 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 3 119 1.0E-52 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HVS_RS09310 089504c50d3269d5793f9106791fec73 127 SUPERFAMILY SSF50692 2 117 5.72E-51 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain HVS_RS09310 089504c50d3269d5793f9106791fec73 127 Gene3D G3DSA:2.40.40.20 1 117 1.8E-55 T 29-03-2018 HVS_RS09310 089504c50d3269d5793f9106791fec73 127 Pfam PF02261 Aspartate decarboxylase 2 114 3.2E-54 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HVS_RS09310 089504c50d3269d5793f9106791fec73 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 94 1.0E-31 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 HVS_RS02635 a3e57614ca1ed9204eaa1ff1a81f8ae5 95 Pfam PF06889 Protein of unknown function (DUF1266) 2 91 2.3E-14 T 29-03-2018 IPR009677 Protein of unknown function DUF1266 HVS_RS10625 807d3e9442456765e7944c3ff40c0947 483 Pfam PF13416 Bacterial extracellular solute-binding protein 64 388 1.6E-34 T 29-03-2018 HVS_RS10625 807d3e9442456765e7944c3ff40c0947 483 Gene3D G3DSA:3.40.190.10 263 404 6.2E-18 T 29-03-2018 HVS_RS10625 807d3e9442456765e7944c3ff40c0947 483 Gene3D G3DSA:3.40.190.10 45 238 5.2E-24 T 29-03-2018 HVS_RS10625 807d3e9442456765e7944c3ff40c0947 483 SUPERFAMILY SSF53850 46 425 8.98E-63 T 29-03-2018 HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 SMART SM00271 4 62 6.5E-34 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 Gene3D G3DSA:2.60.260.20 134 210 1.6E-19 T 29-03-2018 HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 SUPERFAMILY SSF49493 214 297 9.68E-20 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 Pfam PF00226 DnaJ domain 5 67 2.8E-29 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 PRINTS PR00625 DnaJ domain signature 42 62 1.5E-27 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 PRINTS PR00625 DnaJ domain signature 62 81 1.5E-27 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 PRINTS PR00625 DnaJ domain signature 25 40 1.5E-27 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 PRINTS PR00625 DnaJ domain signature 7 25 1.5E-27 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 29-03-2018 IPR018253 DnaJ domain, conserved site HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 SUPERFAMILY SSF46565 1 123 4.97E-33 T 29-03-2018 IPR001623 DnaJ domain HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 SUPERFAMILY SSF49493 133 210 6.15E-15 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 Gene3D G3DSA:2.60.260.20 211 308 3.4E-21 T 29-03-2018 HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 Pfam PF01556 DnaJ C terminal domain 140 287 8.0E-37 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal HVS_RS04210 90a3510c002c162a9f5ece551b3fb05c 308 Gene3D G3DSA:1.10.287.110 1 133 1.5E-34 T 29-03-2018 IPR001623 DnaJ domain HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 Pfam PF02938 GAD domain 319 413 9.2E-29 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 SUPERFAMILY SSF55261 300 427 9.32E-45 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 9 592 1.5E-252 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 SUPERFAMILY SSF50249 10 114 1.89E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 Pfam PF01336 OB-fold nucleic acid binding domain 26 111 1.2E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 Gene3D G3DSA:2.40.50.140 7 117 1.5E-27 T 29-03-2018 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 SUPERFAMILY SSF55681 432 591 2.49E-110 T 29-03-2018 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 SUPERFAMILY SSF55681 117 303 2.49E-110 T 29-03-2018 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 9 592 35.206 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 Pfam PF00152 tRNA synthetases class II (D, K and N) 129 565 1.7E-111 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 Gene3D G3DSA:3.30.930.10 142 594 1.7E-114 T 29-03-2018 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 482 498 4.2E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 526 540 4.2E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 218 231 4.2E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS11155 138ab481b15df019425cf515a57f12ac 600 PRINTS PR01042 Aspartyl-tRNA synthetase signature 201 213 4.2E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 SUPERFAMILY SSF47757 4 67 2.22E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 Pfam PF01739 CheR methyltransferase, SAM binding domain 68 246 6.6E-60 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 PRINTS PR00996 Glutamate methyltransferase family signature 24 37 1.9E-39 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 PRINTS PR00996 Glutamate methyltransferase family signature 215 238 1.9E-39 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 PRINTS PR00996 Glutamate methyltransferase family signature 196 210 1.9E-39 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 PRINTS PR00996 Glutamate methyltransferase family signature 61 73 1.9E-39 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 PRINTS PR00996 Glutamate methyltransferase family signature 98 118 1.9E-39 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 PRINTS PR00996 Glutamate methyltransferase family signature 130 146 1.9E-39 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 SUPERFAMILY SSF53335 68 255 2.72E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 54 4.2E-15 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 Gene3D G3DSA:1.10.155.10 2 66 1.4E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 SMART SM00138 2 255 2.0E-90 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS08060 1601ef2262fbbea87ffa39e065deeb2f 260 Gene3D G3DSA:3.40.50.150 67 257 1.2E-49 T 29-03-2018 HVS_RS00990 861fcf048823d3656bcbf300f4952eee 106 Gene3D G3DSA:1.10.287.1060 3 89 5.9E-7 T 29-03-2018 HVS_RS00990 861fcf048823d3656bcbf300f4952eee 106 SUPERFAMILY SSF140453 4 89 3.27E-7 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS05785 861fcf048823d3656bcbf300f4952eee 106 Gene3D G3DSA:1.10.287.1060 3 89 5.9E-7 T 29-03-2018 HVS_RS05785 861fcf048823d3656bcbf300f4952eee 106 SUPERFAMILY SSF140453 4 89 3.27E-7 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like HVS_RS13920 df817d7c862b4f6a3101d9c82620f890 440 Gene3D G3DSA:3.40.190.10 214 397 0.0019 T 29-03-2018 HVS_RS13920 df817d7c862b4f6a3101d9c82620f890 440 SUPERFAMILY SSF53850 55 434 7.85E-35 T 29-03-2018 HVS_RS13920 df817d7c862b4f6a3101d9c82620f890 440 Pfam PF13416 Bacterial extracellular solute-binding protein 71 343 2.9E-14 T 29-03-2018 HVS_RS13920 df817d7c862b4f6a3101d9c82620f890 440 Gene3D G3DSA:3.40.190.10 44 213 1.3E-21 T 29-03-2018 HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Gene3D G3DSA:3.40.630.40 758 956 5.4E-58 T 29-03-2018 HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 SUPERFAMILY SSF55383 64 148 6.15E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 776 949 1.6E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 SUPERFAMILY SSF53187 775 953 3.77E-51 T 29-03-2018 HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Gene3D G3DSA:3.30.457.10 22 72 2.6E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Gene3D G3DSA:3.30.457.10 136 264 7.4E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Gene3D G3DSA:3.30.457.10 73 135 5.3E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Pfam PF11741 AMIN domain 287 367 8.4E-12 T 29-03-2018 IPR021731 AMIN domain HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Pfam PF11741 AMIN domain 407 493 1.2E-6 T 29-03-2018 IPR021731 AMIN domain HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Pfam PF11741 AMIN domain 562 647 3.2E-16 T 29-03-2018 IPR021731 AMIN domain HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Pfam PF11741 AMIN domain 171 259 1.1E-15 T 29-03-2018 IPR021731 AMIN domain HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 SMART SM00646 834 949 1.2E-34 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 HVS_RS11500 90e337b3701df33cf2d64830fc962715 956 Pfam PF07833 Copper amine oxidase N-terminal domain 62 153 2.7E-29 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 Pfam PF02445 Quinolinate synthetase A protein 9 300 1.7E-122 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 1 302 1.6E-107 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 SUPERFAMILY SSF142754 5 301 4.84E-118 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 302 43.312 T 29-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 Gene3D G3DSA:3.40.50.10800 95 176 8.9E-29 T 29-03-2018 HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 Gene3D G3DSA:3.40.50.10800 4 94 3.2E-22 T 29-03-2018 HVS_RS16015 4c1b91c3679692f85b1db002286d5f26 304 Gene3D G3DSA:3.40.50.10800 177 284 2.0E-34 T 29-03-2018 HVS_RS10685 6d8762c6d79df7aa1b058f21ea9c9f34 81 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 81 7.1E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS10685 6d8762c6d79df7aa1b058f21ea9c9f34 81 SMART SM00862 26 81 7.9E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS10685 6d8762c6d79df7aa1b058f21ea9c9f34 81 Gene3D G3DSA:1.10.10.10 1 81 1.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10685 6d8762c6d79df7aa1b058f21ea9c9f34 81 SUPERFAMILY SSF46894 3 81 1.22E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HVS_RS13635 cfe90bf24f64bc1e737493148ce9dbd4 181 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 80 176 1.5E-10 T 29-03-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A HVS_RS13635 cfe90bf24f64bc1e737493148ce9dbd4 181 Pfam PF03750 Csm2 Type III-A 68 177 2.4E-10 T 29-03-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A HVS_RS02965 eab4ef06ccb3f2bf2c433a900ff4ca2d 341 Gene3D G3DSA:1.10.260.40 1 90 4.3E-20 T 29-03-2018 HVS_RS02965 eab4ef06ccb3f2bf2c433a900ff4ca2d 341 Pfam PF01381 Helix-turn-helix 7 61 1.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS02965 eab4ef06ccb3f2bf2c433a900ff4ca2d 341 SMART SM00530 6 61 1.9E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS02965 eab4ef06ccb3f2bf2c433a900ff4ca2d 341 Gene3D G3DSA:1.25.40.10 202 304 0.025 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS02965 eab4ef06ccb3f2bf2c433a900ff4ca2d 341 Gene3D G3DSA:1.25.40.10 91 201 4.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS02965 eab4ef06ccb3f2bf2c433a900ff4ca2d 341 SUPERFAMILY SSF47413 1 67 1.87E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS02570 6d88b4283ad0224adc07b7b5be1de20e 406 Gene3D G3DSA:3.20.20.300 50 406 3.9E-102 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS02570 6d88b4283ad0224adc07b7b5be1de20e 406 SUPERFAMILY SSF51445 56 404 3.3E-101 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS02570 6d88b4283ad0224adc07b7b5be1de20e 406 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 66 394 1.4E-100 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 HVS_RS11675 c02290196cec5a43946e613f0393c445 413 SUPERFAMILY SSF53300 207 339 5.72E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS11675 c02290196cec5a43946e613f0393c445 413 Pfam PF01882 Protein of unknown function DUF58 162 249 1.1E-19 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS11675 c02290196cec5a43946e613f0393c445 413 Gene3D G3DSA:3.40.50.410 173 368 1.0E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS03305 c9e6f3949c4fac83c529156c0afbfa1e 326 Gene3D G3DSA:2.115.10.20 5 326 5.7E-70 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS03305 c9e6f3949c4fac83c529156c0afbfa1e 326 Pfam PF04616 Glycosyl hydrolases family 43 77 319 1.4E-32 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 HVS_RS03305 c9e6f3949c4fac83c529156c0afbfa1e 326 SUPERFAMILY SSF75005 7 319 2.86E-62 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS13190 febbb30222782ba15d3e539770ac3f10 102 Gene3D G3DSA:1.10.3230.10 3 86 3.1E-4 T 29-03-2018 HVS_RS13190 febbb30222782ba15d3e539770ac3f10 102 Pfam PF05135 Phage gp6-like head-tail connector protein 1 73 7.9E-13 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein HVS_RS12075 5a3eade031c0b1f7a338855ac76d273c 120 SUPERFAMILY SSF52091 1 109 4.71E-30 T 29-03-2018 IPR002645 STAS domain HVS_RS12075 5a3eade031c0b1f7a338855ac76d273c 120 Pfam PF01740 STAS domain 9 107 2.3E-22 T 29-03-2018 IPR002645 STAS domain HVS_RS12075 5a3eade031c0b1f7a338855ac76d273c 120 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 105 2.1E-29 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 HVS_RS12075 5a3eade031c0b1f7a338855ac76d273c 120 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 108 6.6E-39 T 29-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 HVS_RS12075 5a3eade031c0b1f7a338855ac76d273c 120 Gene3D G3DSA:3.30.750.24 1 120 1.3E-25 T 29-03-2018 IPR002645 STAS domain HVS_RS01055 41043301066c0b8bccb2a4cb541c3c1b 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 2.3E-90 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS05880 43097de24a1406c6219d8abb7c7b279e 140 SUPERFAMILY SSF55874 32 138 5.37E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05880 43097de24a1406c6219d8abb7c7b279e 140 Pfam PF13581 Histidine kinase-like ATPase domain 13 137 1.1E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05880 43097de24a1406c6219d8abb7c7b279e 140 Gene3D G3DSA:3.30.565.10 4 140 1.5E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09790 8c2856e1f6226f78585cd7fa0a2c7170 425 Gene3D G3DSA:3.90.550.10 2 167 8.5E-9 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09790 8c2856e1f6226f78585cd7fa0a2c7170 425 SUPERFAMILY SSF53448 6 150 2.25E-12 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09790 8c2856e1f6226f78585cd7fa0a2c7170 425 Gene3D G3DSA:1.25.40.10 294 396 0.16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS09790 8c2856e1f6226f78585cd7fa0a2c7170 425 Pfam PF00535 Glycosyl transferase family 2 7 146 1.4E-8 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HVS_RS09790 8c2856e1f6226f78585cd7fa0a2c7170 425 Gene3D G3DSA:1.25.40.10 168 293 9.0E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS09790 8c2856e1f6226f78585cd7fa0a2c7170 425 SUPERFAMILY SSF81901 182 328 5.75E-9 T 29-03-2018 HVS_RS08735 8e14dc3b7bca87b700418800f42ca69e 377 Pfam PF01098 Cell cycle protein 19 368 3.2E-81 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 HVS_RS08735 8e14dc3b7bca87b700418800f42ca69e 377 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 368 2.8E-102 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 HVS_RS16170 2fff9c889c7441d8a255cd58b6fd259c 241 Pfam PF02527 rRNA small subunit methyltransferase G 26 205 4.6E-57 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HVS_RS16170 2fff9c889c7441d8a255cd58b6fd259c 241 PIRSF PIRSF003078 2 223 4.7E-61 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HVS_RS16170 2fff9c889c7441d8a255cd58b6fd259c 241 SUPERFAMILY SSF53335 8 240 2.97E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS16170 2fff9c889c7441d8a255cd58b6fd259c 241 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 18 217 30.234 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HVS_RS16170 2fff9c889c7441d8a255cd58b6fd259c 241 Gene3D G3DSA:3.40.50.150 2 241 3.2E-38 T 29-03-2018 HVS_RS16170 2fff9c889c7441d8a255cd58b6fd259c 241 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 31 220 5.1E-59 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 Gene3D G3DSA:3.40.50.620 2 202 1.0E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 Pfam PF00579 tRNA synthetases class I (W and Y) 5 281 2.0E-75 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 Gene3D G3DSA:1.10.240.10 203 322 4.1E-36 T 29-03-2018 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 3.5E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 3.5E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 3.5E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 145 166 3.5E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 327 36.6 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 324 1.2E-97 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 HVS_RS08240 1de9f9cdf8e7880b1e39e102c81deead 329 SUPERFAMILY SSF52374 5 326 1.45E-97 T 29-03-2018 HVS_RS13975 6aedcb614df7fc3a8f155df9828a5406 511 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 358 495 7.9E-17 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HVS_RS13975 6aedcb614df7fc3a8f155df9828a5406 511 Pfam PF01943 Polysaccharide biosynthesis protein 8 307 1.2E-27 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HVS_RS13975 6aedcb614df7fc3a8f155df9828a5406 511 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 467 4.9E-120 T 29-03-2018 IPR014249 Sporulation stage V protein B HVS_RS13975 6aedcb614df7fc3a8f155df9828a5406 511 PIRSF PIRSF038958 1 511 1.4E-117 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 Gene3D G3DSA:2.30.30.180 89 152 3.3E-16 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 Pfam PF17384 RimP C-terminal SH3 domain 88 145 2.5E-9 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 SUPERFAMILY SSF75420 4 85 1.1E-27 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 SUPERFAMILY SSF74942 86 152 5.62E-15 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 154 23.594 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 Gene3D G3DSA:3.30.300.70 1 82 2.8E-28 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal HVS_RS10540 24846bd3bf545d2911eea67267b4b93f 154 Pfam PF02576 RimP N-terminal domain 13 85 5.4E-31 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal HVS_RS04440 4c5732bb0b9044a82e9047eeb7ae68e6 360 SUPERFAMILY SSF53756 162 350 1.92E-11 T 29-03-2018 HVS_RS04440 4c5732bb0b9044a82e9047eeb7ae68e6 360 Gene3D G3DSA:3.40.50.2000 184 336 7.8E-13 T 29-03-2018 HVS_RS04440 4c5732bb0b9044a82e9047eeb7ae68e6 360 Gene3D G3DSA:3.40.50.2000 12 105 2.9E-6 T 29-03-2018 HVS_RS04440 4c5732bb0b9044a82e9047eeb7ae68e6 360 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 3 290 4.3E-70 T 29-03-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase HVS_RS04440 4c5732bb0b9044a82e9047eeb7ae68e6 360 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 296 2.2E-4 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 HVS_RS02775 f92315f9bb28ac082f992290323471ea 278 Gene3D G3DSA:1.10.10.10 171 255 4.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02775 f92315f9bb28ac082f992290323471ea 278 Pfam PF08721 TnsA endonuclease C terminal 166 248 5.1E-22 T 29-03-2018 IPR014832 TnsA endonuclease C-terminal HVS_RS02775 f92315f9bb28ac082f992290323471ea 278 SUPERFAMILY SSF52980 8 167 1.5E-53 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HVS_RS02775 f92315f9bb28ac082f992290323471ea 278 Gene3D G3DSA:3.40.1350.10 7 167 8.8E-43 T 29-03-2018 HVS_RS02775 f92315f9bb28ac082f992290323471ea 278 Pfam PF08722 TnsA endonuclease N terminal 75 164 4.0E-16 T 29-03-2018 IPR014833 TnsA endonuclease, N-terminal HVS_RS07935 a4a752c006635941dca400f221cb418a 394 Gene3D G3DSA:3.20.20.360 31 347 7.0E-30 T 29-03-2018 HVS_RS07935 a4a752c006635941dca400f221cb418a 394 SUPERFAMILY SSF51621 34 256 4.55E-17 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HVS_RS07935 a4a752c006635941dca400f221cb418a 394 SUPERFAMILY SSF51621 289 324 4.55E-17 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HVS_RS07935 a4a752c006635941dca400f221cb418a 394 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 378 2.7E-128 T 29-03-2018 HVS_RS04360 45f7f020d015fb7a1ec404a301e9140a 387 Pfam PF01609 Transposase DDE domain 107 342 1.2E-18 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HVS_RS04360 45f7f020d015fb7a1ec404a301e9140a 387 Pfam PF13808 DDE_Tnp_1-associated 12 98 2.2E-31 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal HVS_RS05385 5059be2e6fe75263c097450789f1af13 171 Pfam PF04093 rod shape-determining protein MreD 8 157 2.6E-14 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 HVS_RS05385 5059be2e6fe75263c097450789f1af13 171 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 156 6.3E-16 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 HVS_RS05385 5059be2e6fe75263c097450789f1af13 171 PIRSF PIRSF037497 3 171 1.0E-46 T 29-03-2018 IPR017225 Cell shape-determining protein MreD, predicted HVS_RS01070 3ebb3421381855e3c0be7c99b5ef41bc 266 Gene3D G3DSA:3.40.50.300 13 207 2.0E-10 T 29-03-2018 HVS_RS01070 3ebb3421381855e3c0be7c99b5ef41bc 266 Pfam PF13401 AAA domain 42 170 5.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01070 3ebb3421381855e3c0be7c99b5ef41bc 266 SMART SM00382 41 194 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01070 3ebb3421381855e3c0be7c99b5ef41bc 266 SUPERFAMILY SSF52540 15 259 2.2E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13765 30476240614743583dda40dec8af6795 490 Gene3D G3DSA:1.10.10.60 93 118 0.18 T 29-03-2018 HVS_RS13765 30476240614743583dda40dec8af6795 490 Gene3D G3DSA:1.10.10.60 3 37 0.0039 T 29-03-2018 HVS_RS13765 30476240614743583dda40dec8af6795 490 Pfam PF00665 Integrase core domain 125 251 8.3E-20 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS13765 30476240614743583dda40dec8af6795 490 Gene3D G3DSA:1.10.10.60 55 92 0.027 T 29-03-2018 HVS_RS13765 30476240614743583dda40dec8af6795 490 Gene3D G3DSA:3.30.420.10 119 342 3.2E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13765 30476240614743583dda40dec8af6795 490 SUPERFAMILY SSF53098 125 290 7.97E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05415 c43d056a910d73dba3e15e930acbebce 357 SUPERFAMILY SSF51261 219 349 1.26E-30 T 29-03-2018 IPR011055 Duplicated hybrid motif HVS_RS05415 c43d056a910d73dba3e15e930acbebce 357 Gene3D G3DSA:2.70.70.10 132 354 1.1E-29 T 29-03-2018 HVS_RS05415 c43d056a910d73dba3e15e930acbebce 357 Pfam PF01551 Peptidase family M23 251 345 2.5E-20 T 29-03-2018 IPR016047 Peptidase M23 HVS_RS01300 8802fa6b55a68342ca501cd4bfff4b33 113 Pfam PF12643 MazG-like family 10 97 7.7E-26 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 Pfam PF01297 Zinc-uptake complex component A periplasmic 47 320 5.1E-73 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 Gene3D G3DSA:3.40.50.1980 38 197 4.6E-41 T 29-03-2018 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 44 65 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 279 297 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 203 220 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 88 107 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 145 164 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 300 318 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00691 Adhesin B signature 69 87 4.3E-26 T 29-03-2018 IPR006129 Adhesin B GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00690 Adhesin family signature 75 88 1.1E-42 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00690 Adhesin family signature 256 274 1.1E-42 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00690 Adhesin family signature 88 105 1.1E-42 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00690 Adhesin family signature 287 306 1.1E-42 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00690 Adhesin family signature 203 224 1.1E-42 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 PRINTS PR00690 Adhesin family signature 44 62 1.1E-42 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 Gene3D G3DSA:3.40.50.1980 198 322 4.6E-37 T 29-03-2018 HVS_RS01620 2706aa73353adbca628c2194520b5a1f 323 SUPERFAMILY SSF53807 41 322 2.21E-76 T 29-03-2018 HVS_RS14315 3c8a39f14d1d07165005faeb00612be6 234 SUPERFAMILY SSF53335 4 231 2.81E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS14315 3c8a39f14d1d07165005faeb00612be6 234 Gene3D G3DSA:3.40.50.150 2 125 4.9E-24 T 29-03-2018 HVS_RS14315 3c8a39f14d1d07165005faeb00612be6 234 Gene3D G3DSA:2.20.25.110 129 190 5.4E-21 T 29-03-2018 HVS_RS14315 3c8a39f14d1d07165005faeb00612be6 234 Pfam PF13649 Methyltransferase domain 27 121 1.4E-17 T 29-03-2018 HVS_RS13435 ee49db09c9da3b6391c9f6ce1122b3fa 374 Gene3D G3DSA:3.40.50.2000 178 347 9.9E-29 T 29-03-2018 HVS_RS13435 ee49db09c9da3b6391c9f6ce1122b3fa 374 Pfam PF13477 Glycosyl transferase 4-like 3 147 1.1E-24 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS13435 ee49db09c9da3b6391c9f6ce1122b3fa 374 Gene3D G3DSA:3.40.50.2000 16 177 9.8E-14 T 29-03-2018 HVS_RS13435 ee49db09c9da3b6391c9f6ce1122b3fa 374 Pfam PF00534 Glycosyl transferases group 1 184 334 3.4E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS13435 ee49db09c9da3b6391c9f6ce1122b3fa 374 SUPERFAMILY SSF53756 19 365 1.44E-57 T 29-03-2018 HVS_RS02270 0afa6712a045ac5ea8d5afd56b6be9f4 340 Pfam PF00294 pfkB family carbohydrate kinase 1 314 6.4E-41 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB HVS_RS02270 0afa6712a045ac5ea8d5afd56b6be9f4 340 SUPERFAMILY SSF53613 1 330 1.43E-83 T 29-03-2018 IPR029056 Ribokinase-like HVS_RS02270 0afa6712a045ac5ea8d5afd56b6be9f4 340 Gene3D G3DSA:3.40.1190.20 1 339 1.1E-54 T 29-03-2018 IPR029056 Ribokinase-like HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 240 6.1E-101 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 SUPERFAMILY SSF75625 3 244 6.54E-98 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 241 37.389 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 Pfam PF01709 Transcriptional regulator 5 239 8.8E-104 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 Gene3D G3DSA:1.10.10.200 1 78 5.8E-33 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 Gene3D G3DSA:3.30.70.980 83 176 1.9E-33 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HVS_RS15775 6d16088902076aaa183bb0ed31186d2a 245 Gene3D G3DSA:3.30.70.980 177 245 3.0E-13 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 HVS_RS05030 dc62e40c41b624a7df70a1a1abcc9ca9 480 TIGRFAM TIGR02710 TIGR02710: CRISPR-associated protein, TIGR02710 family 66 458 1.1E-57 T 29-03-2018 IPR014082 CRISPR-associated protein, Cas02710 HVS_RS05030 dc62e40c41b624a7df70a1a1abcc9ca9 480 Gene3D G3DSA:3.40.50.10770 54 189 8.7E-21 T 29-03-2018 HVS_RS05030 dc62e40c41b624a7df70a1a1abcc9ca9 480 SUPERFAMILY SSF52980 57 194 2.14E-7 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HVS_RS05030 dc62e40c41b624a7df70a1a1abcc9ca9 480 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 66 459 4.0E-117 T 29-03-2018 HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 SUPERFAMILY SSF49313 6 92 2.35E-11 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 Gene3D G3DSA:1.10.1330.10 328 397 4.7E-4 T 29-03-2018 HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 ProSitePatterns PS00018 EF-hand calcium-binding domain. 330 342 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 Pfam PF00404 Dockerin type I repeat 366 386 6.9E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 SUPERFAMILY SSF63446 326 396 5.4E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 Gene3D G3DSA:3.40.1850.10 232 327 1.3E-8 T 29-03-2018 HVS_RS09710 3d2fa387a812c5b9102ffbbc1c7389b5 397 Gene3D G3DSA:2.60.40.10 1 92 3.1E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 Gene3D G3DSA:3.40.920.10 1 170 7.6E-33 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 SUPERFAMILY SSF53323 1 204 2.88E-36 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 193 432 4.0E-59 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 SUPERFAMILY SSF52518 181 438 7.36E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 164 1.6E-28 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 Gene3D G3DSA:3.40.50.970 178 485 6.4E-57 T 29-03-2018 HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 2 554 1.3E-207 T 29-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 HVS_RS07660 0eb1f6c59e24bd274446dac840651eb8 559 SUPERFAMILY SSF52922 450 555 2.86E-15 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS06670 86cc57453092c08ac0090507565d742f 152 SUPERFAMILY SSF52540 5 137 6.36E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS06670 86cc57453092c08ac0090507565d742f 152 Pfam PF13401 AAA domain 10 57 1.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS13950 8705ccd31e1b3f5d2cfbaaa77475e2da 512 Gene3D G3DSA:3.90.76.10 46 185 1.4E-29 T 29-03-2018 HVS_RS13950 8705ccd31e1b3f5d2cfbaaa77475e2da 512 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 422 6.8E-69 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain HVS_RS13950 8705ccd31e1b3f5d2cfbaaa77475e2da 512 PIRSF PIRSF002741 3 506 4.3E-82 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 HVS_RS13950 8705ccd31e1b3f5d2cfbaaa77475e2da 512 Gene3D G3DSA:3.10.105.10 282 472 2.7E-40 T 29-03-2018 HVS_RS13950 8705ccd31e1b3f5d2cfbaaa77475e2da 512 Gene3D G3DSA:3.40.190.10 186 281 1.6E-14 T 29-03-2018 HVS_RS13950 8705ccd31e1b3f5d2cfbaaa77475e2da 512 SUPERFAMILY SSF53850 29 490 5.89E-102 T 29-03-2018 HVS_RS13280 117e9da4bcf673f4b5c9bf5e6409cd5b 151 Gene3D G3DSA:1.10.10.10 60 149 4.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 Gene3D G3DSA:3.65.10.10 19 222 1.1E-46 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 SUPERFAMILY SSF55205 3 418 3.71E-116 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 PIRSF PIRSF000505 1 422 6.1E-131 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 ProSitePatterns PS00885 EPSP synthase signature 2. 330 348 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 Gene3D G3DSA:3.65.10.10 223 414 1.6E-57 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 418 31.778 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 410 6.8E-113 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS11950 02fcf6210b1c26c89ddecf4ade3c925b 424 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 417 5.4E-127 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 HVS_RS11075 67ad4f594170546cc166863263bdecd3 89 Hamap MF_01503 UPF0296 protein . 1 89 29.989 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 HVS_RS11075 67ad4f594170546cc166863263bdecd3 89 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 3 76 9.0E-36 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 HVS_RS11075 67ad4f594170546cc166863263bdecd3 89 Pfam PF04025 Domain of unknown function (DUF370) 3 75 3.1E-37 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 HVS_RS06930 30aec4a00a76fe27d990fd529d0d89d7 251 Gene3D G3DSA:3.60.10.10 1 251 2.8E-55 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase HVS_RS06930 30aec4a00a76fe27d990fd529d0d89d7 251 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 248 1.7E-95 T 29-03-2018 HVS_RS06930 30aec4a00a76fe27d990fd529d0d89d7 251 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 249 2.4E-100 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HVS_RS06930 30aec4a00a76fe27d990fd529d0d89d7 251 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 6.4E-21 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase HVS_RS06930 30aec4a00a76fe27d990fd529d0d89d7 251 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HVS_RS06930 30aec4a00a76fe27d990fd529d0d89d7 251 SUPERFAMILY SSF56219 1 250 1.96E-80 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase HVS_RS07920 072aa7d94768158c553173337b27f2d2 273 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 2 216 4.9E-10 T 29-03-2018 IPR006380 Sucrose-phosphatase-like, N-terminal HVS_RS07920 072aa7d94768158c553173337b27f2d2 273 SUPERFAMILY SSF56784 2 225 1.24E-20 T 29-03-2018 IPR023214 HAD-like domain HVS_RS07920 072aa7d94768158c553173337b27f2d2 273 PIRSF PIRSF030802 1 238 1.3E-18 T 29-03-2018 IPR024197 Uncharacterised conserved protein UCP030802 HVS_RS07920 072aa7d94768158c553173337b27f2d2 273 Gene3D G3DSA:3.40.50.1000 1 231 6.0E-14 T 29-03-2018 IPR023214 HAD-like domain HVS_RS10605 e7214b7bd216ac1fe60beab77161f57a 371 Pfam PF14286 DHHW protein 120 329 3.1E-10 T 29-03-2018 IPR025945 DHHW protein HVS_RS13155 2cf4499492feef716255df261ee17144 134 SMART SM00670 1 116 1.1E-5 T 29-03-2018 IPR002716 PIN domain HVS_RS13155 2cf4499492feef716255df261ee17144 134 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 115 1.0E-11 T 29-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component HVS_RS13155 2cf4499492feef716255df261ee17144 134 SUPERFAMILY SSF88723 1 120 2.69E-13 T 29-03-2018 IPR029060 PIN domain-like HVS_RS13155 2cf4499492feef716255df261ee17144 134 Pfam PF13470 PIN domain 2 112 4.1E-13 T 29-03-2018 IPR002716 PIN domain HVS_RS13155 2cf4499492feef716255df261ee17144 134 Gene3D G3DSA:3.40.50.1010 1 132 2.1E-14 T 29-03-2018 IPR029060 PIN domain-like HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 Gene3D G3DSA:3.40.50.720 5 287 1.0E-61 T 29-03-2018 HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 39 285 7.7E-52 T 29-03-2018 HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 SUPERFAMILY SSF51735 26 286 1.24E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 217 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 268 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 29 46 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 173 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 236 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 2.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 198 217 2.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS09810 879e51c5a45677d3b4464196be7bb407 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 171 2.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 Gene3D G3DSA:2.130.10.150 204 447 8.0E-8 T 29-03-2018 HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 Gene3D G3DSA:3.30.457.10 85 153 1.7E-21 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 Gene3D G3DSA:3.30.457.10 31 84 6.8E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 SUPERFAMILY SSF55383 76 150 5.89E-20 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 Pfam PF07833 Copper amine oxidase N-terminal domain 74 150 1.4E-22 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 SUPERFAMILY SSF63825 201 407 2.75E-12 T 29-03-2018 HVS_RS08290 c2d94464be861f2000702c7e27664df5 499 Pfam PF16472 Domain of unknown function (DUF5050) 193 459 5.3E-35 T 29-03-2018 IPR032485 Domain of unknown function DUF5050 HVS_RS02210 5322489d4845dbfe639fb784274b67f6 411 SUPERFAMILY SSF103473 1 408 1.96E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain HVS_RS02210 5322489d4845dbfe639fb784274b67f6 411 Pfam PF07690 Major Facilitator Superfamily 14 363 1.8E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HVS_RS02210 5322489d4845dbfe639fb784274b67f6 411 Gene3D G3DSA:1.20.1250.20 2 198 3.2E-22 T 29-03-2018 HVS_RS02210 5322489d4845dbfe639fb784274b67f6 411 Gene3D G3DSA:1.20.1250.20 213 408 6.7E-19 T 29-03-2018 HVS_RS03295 8c971a46e43306253f491534f92b5775 618 SUPERFAMILY SSF53649 291 499 5.01E-16 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS03295 8c971a46e43306253f491534f92b5775 618 Gene3D G3DSA:3.40.720.10 236 552 2.8E-17 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS03295 8c971a46e43306253f491534f92b5775 618 Pfam PF00884 Sulfatase 242 520 1.1E-24 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 HVS_RS03640 6cea02a35115f505149fc1f2e6a70252 167 Hamap MF_01398 ATP synthase subunit b [atpF]. 12 151 10.916 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HVS_RS03640 6cea02a35115f505149fc1f2e6a70252 167 SUPERFAMILY SSF81573 93 148 2.88E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS03640 6cea02a35115f505149fc1f2e6a70252 167 Gene3D G3DSA:1.20.5.620 90 149 4.4E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS03640 6cea02a35115f505149fc1f2e6a70252 167 Pfam PF00430 ATP synthase B/B' CF(0) 20 149 5.1E-17 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HVS_RS08055 14e9f2aa0795a5ef3ede655fe2aa8910 95 Pfam PF03698 Uncharacterised protein family (UPF0180) 6 89 4.2E-19 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 HVS_RS07140 7cbdc4d626564d234e18ce47e6e625be 66 Pfam PF02597 ThiS family 7 66 6.7E-14 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 HVS_RS07140 7cbdc4d626564d234e18ce47e6e625be 66 Gene3D G3DSA:3.10.20.30 2 66 3.9E-20 T 29-03-2018 IPR012675 Beta-grasp domain HVS_RS07140 7cbdc4d626564d234e18ce47e6e625be 66 SUPERFAMILY SSF54285 3 65 7.52E-18 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp HVS_RS07140 7cbdc4d626564d234e18ce47e6e625be 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.1E-23 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 8.1E-7 T 29-03-2018 HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 247 262 8.1E-7 T 29-03-2018 HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 36 1.8E-7 T 29-03-2018 HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 SUPERFAMILY SSF51905 238 322 8.49E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 SUPERFAMILY SSF51905 1 160 8.49E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 Gene3D G3DSA:3.30.9.10 152 309 2.7E-4 T 29-03-2018 HVS_RS13845 85278bd8343f9199094fbf13a43ae358 359 Gene3D G3DSA:3.50.50.60 1 103 2.5E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HVS_RS07340 aff2b5f7e74faf45ddd26a78380f04b3 83 TIGRFAM TIGR04354 amphi-Trp: amphi-Trp domain 3 67 5.0E-9 T 29-03-2018 IPR027598 Amphi-Trp domain HVS_RS00080 521c87d26435fb06549c720f8de7654c 193 Pfam PF00395 S-layer homology domain 89 131 3.5E-14 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS00080 521c87d26435fb06549c720f8de7654c 193 Pfam PF00395 S-layer homology domain 39 68 3.8E-6 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 Gene3D G3DSA:1.20.120.530 81 230 2.2E-34 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 4.4E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 SUPERFAMILY SSF48008 84 220 2.07E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 SUPERFAMILY SSF46785 11 82 1.09E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 49 1.9E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 68 1.9E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 SMART SM00895 88 212 3.3E-20 T 29-03-2018 IPR011711 GntR, C-terminal HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 Pfam PF07729 FCD domain 88 211 1.8E-27 T 29-03-2018 IPR011711 GntR, C-terminal HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 Gene3D G3DSA:1.10.10.10 3 80 5.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 4.9E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 4.9E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS00180 1877915103023cacee0e5c2ee43a10b8 230 SMART SM00345 20 78 8.9E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS07060 0e234cad516bea17a4a770e146063753 245 Pfam PF13672 Protein phosphatase 2C 14 206 6.6E-19 T 29-03-2018 HVS_RS07060 0e234cad516bea17a4a770e146063753 245 SUPERFAMILY SSF81606 2 242 3.53E-64 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07060 0e234cad516bea17a4a770e146063753 245 Gene3D G3DSA:3.60.40.10 1 243 7.1E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07060 0e234cad516bea17a4a770e146063753 245 SMART SM00331 7 244 1.7E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS07060 0e234cad516bea17a4a770e146063753 245 SMART SM00332 1 242 2.9E-26 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS12715 dd25e6ae1490328bb75c214c56c9ccd3 130 SUPERFAMILY SSF111038 3 130 3.4E-51 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS12715 dd25e6ae1490328bb75c214c56c9ccd3 130 PIRSF PIRSF004681 1 130 3.5E-46 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS12715 dd25e6ae1490328bb75c214c56c9ccd3 130 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 93 111 - T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS12715 dd25e6ae1490328bb75c214c56c9ccd3 130 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 3 130 1.7E-53 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS12715 dd25e6ae1490328bb75c214c56c9ccd3 130 Pfam PF01894 Uncharacterised protein family UPF0047 16 128 2.8E-45 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS12715 dd25e6ae1490328bb75c214c56c9ccd3 130 Gene3D G3DSA:2.60.120.460 1 129 2.8E-51 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 HVS_RS14165 f517c155fa11825bd20afe1af3d89b6e 145 Gene3D G3DSA:3.40.50.150 2 138 2.3E-21 T 29-03-2018 HVS_RS14165 f517c155fa11825bd20afe1af3d89b6e 145 Pfam PF13649 Methyltransferase domain 7 101 1.2E-14 T 29-03-2018 HVS_RS14165 f517c155fa11825bd20afe1af3d89b6e 145 SUPERFAMILY SSF53335 3 118 1.67E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS11840 3a783638c62ea3b7f8011e83b0f6782a 210 Gene3D G3DSA:3.80.30.20 20 145 5.2E-21 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe HVS_RS11840 3a783638c62ea3b7f8011e83b0f6782a 210 Pfam PF13394 4Fe-4S single cluster domain 22 106 1.5E-12 T 29-03-2018 HVS_RS11840 3a783638c62ea3b7f8011e83b0f6782a 210 Pfam PF04055 Radical SAM superfamily 24 98 1.5E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS11840 3a783638c62ea3b7f8011e83b0f6782a 210 SUPERFAMILY SSF102114 26 99 1.83E-20 T 29-03-2018 HVS_RS11840 3a783638c62ea3b7f8011e83b0f6782a 210 PIRSF PIRSF000370 1 209 7.0E-67 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HVS_RS11840 3a783638c62ea3b7f8011e83b0f6782a 210 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 206 38.287 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 HVS_RS03380 4b79c8ea73116debbd8912bb7e04d3bf 164 SUPERFAMILY SSF54523 15 68 3.37E-10 T 29-03-2018 HVS_RS03380 4b79c8ea73116debbd8912bb7e04d3bf 164 Gene3D G3DSA:3.30.700.10 15 164 5.7E-13 T 29-03-2018 HVS_RS03380 4b79c8ea73116debbd8912bb7e04d3bf 164 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 34 2.3E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS03380 4b79c8ea73116debbd8912bb7e04d3bf 164 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 34 3.6E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS09555 9044a6f6c641f5a845656de200ac49d1 370 Pfam PF03845 Spore germination protein 11 323 2.6E-38 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS09555 9044a6f6c641f5a845656de200ac49d1 370 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 11 361 9.0E-51 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS05820 8bfdfec2bca5495e11e72844bd11b4cc 949 Gene3D G3DSA:1.20.120.20 695 930 5.4E-12 T 29-03-2018 HVS_RS05820 8bfdfec2bca5495e11e72844bd11b4cc 949 Gene3D G3DSA:1.20.120.20 448 690 0.0015 T 29-03-2018 HVS_RS05820 8bfdfec2bca5495e11e72844bd11b4cc 949 Gene3D G3DSA:3.40.50.1820 80 351 3.6E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS05820 8bfdfec2bca5495e11e72844bd11b4cc 949 Pfam PF11187 Protein of unknown function (DUF2974) 108 256 1.8E-18 T 29-03-2018 IPR024499 Protein of unknown function DUF2974 HVS_RS05820 8bfdfec2bca5495e11e72844bd11b4cc 949 SUPERFAMILY SSF53474 130 271 1.04E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS13785 6c6880598037aa3b0a3bbff17cf59f8d 302 Pfam PF13394 4Fe-4S single cluster domain 13 108 5.5E-8 T 29-03-2018 HVS_RS13785 6c6880598037aa3b0a3bbff17cf59f8d 302 SUPERFAMILY SSF102114 7 297 7.65E-32 T 29-03-2018 HVS_RS13785 6c6880598037aa3b0a3bbff17cf59f8d 302 Gene3D G3DSA:3.20.20.70 2 296 5.6E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS13785 6c6880598037aa3b0a3bbff17cf59f8d 302 SMART SM00729 5 214 0.0065 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS13785 6c6880598037aa3b0a3bbff17cf59f8d 302 Pfam PF04055 Radical SAM superfamily 13 160 1.8E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS09335 6990702899252efbf93b019fb5708566 221 TIGRFAM TIGR00277 HDIG: HDIG domain 32 91 2.3E-7 T 29-03-2018 IPR006675 HDIG domain HVS_RS09335 6990702899252efbf93b019fb5708566 221 SMART SM00471 31 146 3.4E-6 T 29-03-2018 IPR003607 HD/PDEase domain HVS_RS09335 6990702899252efbf93b019fb5708566 221 Gene3D G3DSA:1.10.3210.10 14 200 3.9E-17 T 29-03-2018 HVS_RS09335 6990702899252efbf93b019fb5708566 221 SUPERFAMILY SSF109604 30 164 6.77E-26 T 29-03-2018 HVS_RS09335 6990702899252efbf93b019fb5708566 221 Pfam PF01966 HD domain 36 135 5.2E-9 T 29-03-2018 IPR006674 HD domain HVS_RS00635 5770e93a315b84e124b9ead4d367eaad 112 SUPERFAMILY SSF52091 1 109 4.12E-27 T 29-03-2018 IPR002645 STAS domain HVS_RS00635 5770e93a315b84e124b9ead4d367eaad 112 Gene3D G3DSA:3.30.750.24 1 112 5.9E-22 T 29-03-2018 IPR002645 STAS domain HVS_RS00635 5770e93a315b84e124b9ead4d367eaad 112 Pfam PF01740 STAS domain 3 107 1.4E-18 T 29-03-2018 IPR002645 STAS domain HVS_RS00635 5770e93a315b84e124b9ead4d367eaad 112 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 3.4E-27 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 HVS_RS11165 5f76554d7c51754d13a84e1d01f02e75 200 SUPERFAMILY SSF56281 1 198 4.85E-49 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11165 5f76554d7c51754d13a84e1d01f02e75 200 Pfam PF00753 Metallo-beta-lactamase superfamily 11 187 3.2E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11165 5f76554d7c51754d13a84e1d01f02e75 200 SMART SM00849 12 187 1.1E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS11165 5f76554d7c51754d13a84e1d01f02e75 200 Gene3D G3DSA:3.60.15.10 1 198 3.4E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 Pfam PF03705 CheR methyltransferase, all-alpha domain 7 58 8.3E-15 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 SUPERFAMILY SSF53335 74 270 1.45E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 SUPERFAMILY SSF47757 2 73 2.75E-16 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 Gene3D G3DSA:3.40.50.150 73 272 3.4E-53 T 29-03-2018 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PIRSF PIRSF000410 1 272 1.5E-97 T 29-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 Gene3D G3DSA:1.10.155.10 1 72 8.7E-15 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 6.1E-42 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PRINTS PR00996 Glutamate methyltransferase family signature 231 254 6.1E-42 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PRINTS PR00996 Glutamate methyltransferase family signature 212 226 6.1E-42 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PRINTS PR00996 Glutamate methyltransferase family signature 67 79 6.1E-42 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 6.1E-42 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 6.1E-42 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 SMART SM00138 6 272 7.8E-100 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 HVS_RS09680 9aa210fbede334118866c5102c5ec99c 272 Pfam PF01739 CheR methyltransferase, SAM binding domain 74 264 6.2E-66 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal HVS_RS04200 b417bcc072bba98e4550a4d6b2484daf 336 Pfam PF00534 Glycosyl transferases group 1 160 304 2.5E-25 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS04200 b417bcc072bba98e4550a4d6b2484daf 336 Pfam PF13439 Glycosyltransferase Family 4 22 134 7.3E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 HVS_RS04200 b417bcc072bba98e4550a4d6b2484daf 336 SUPERFAMILY SSF53756 9 334 1.61E-57 T 29-03-2018 HVS_RS04200 b417bcc072bba98e4550a4d6b2484daf 336 Gene3D G3DSA:3.40.50.2000 127 331 8.9E-31 T 29-03-2018 HVS_RS11580 0f817855de45f9457f720a7170d3ac17 615 SUPERFAMILY SSF102114 220 610 2.35E-53 T 29-03-2018 HVS_RS11580 0f817855de45f9457f720a7170d3ac17 615 Gene3D G3DSA:3.20.20.70 166 562 1.1E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS11580 0f817855de45f9457f720a7170d3ac17 615 SMART SM00729 258 483 2.8E-26 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS11580 0f817855de45f9457f720a7170d3ac17 615 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 7 611 2.4E-303 T 29-03-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM HVS_RS11580 0f817855de45f9457f720a7170d3ac17 615 Pfam PF04055 Radical SAM superfamily 264 426 7.8E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS12485 a71de3fa54dcbfef2016cfd4319c11b9 401 Pfam PF01926 50S ribosome-binding GTPase 12 126 6.1E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 HVS_RS12485 a71de3fa54dcbfef2016cfd4319c11b9 401 SUPERFAMILY SSF52540 10 174 1.13E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12485 a71de3fa54dcbfef2016cfd4319c11b9 401 Gene3D G3DSA:3.40.50.300 1 56 2.1E-14 T 29-03-2018 HVS_RS12485 a71de3fa54dcbfef2016cfd4319c11b9 401 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 165 4.9E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 HVS_RS12485 a71de3fa54dcbfef2016cfd4319c11b9 401 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 3 394 1.8E-171 T 29-03-2018 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF HVS_RS12485 a71de3fa54dcbfef2016cfd4319c11b9 401 Gene3D G3DSA:3.40.50.300 57 177 1.1E-20 T 29-03-2018 HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 45 61 3.4E-28 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 29 45 3.4E-28 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 12 29 3.4E-28 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 61 77 3.4E-28 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 SUPERFAMILY SSF51219 11 76 2.3E-32 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 Pfam PF02081 Tryptophan RNA-binding attenuator protein 10 75 8.0E-40 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain HVS_RS10725 2e167c82cb9370597dd8d42133a5ac58 77 Gene3D G3DSA:2.60.40.50 11 76 1.3E-38 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain HVS_RS10010 4114aedbeaf4a79a09324d28f3f14326 194 Gene3D G3DSA:3.40.50.1950 6 188 1.5E-28 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HVS_RS10010 4114aedbeaf4a79a09324d28f3f14326 194 PIRSF PIRSF001390 1 193 4.2E-84 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B HVS_RS10010 4114aedbeaf4a79a09324d28f3f14326 194 SUPERFAMILY SSF52507 7 191 1.07E-31 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HVS_RS10010 4114aedbeaf4a79a09324d28f3f14326 194 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 7 192 1.0E-79 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B HVS_RS10010 4114aedbeaf4a79a09324d28f3f14326 194 Pfam PF02441 Flavoprotein 7 144 1.4E-19 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 HVS_RS07170 a1bac970fdd37262270bd1878eddd6d5 172 Gene3D G3DSA:3.40.630.30 1 170 4.3E-20 T 29-03-2018 HVS_RS07170 a1bac970fdd37262270bd1878eddd6d5 172 SUPERFAMILY SSF55729 8 158 3.9E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS07170 a1bac970fdd37262270bd1878eddd6d5 172 Pfam PF00583 Acetyltransferase (GNAT) family 33 146 2.0E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 PIRSF PIRSF002144 1 94 2.4E-35 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 Gene3D G3DSA:3.30.860.10 1 92 6.9E-41 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 SUPERFAMILY SSF54570 2 84 1.83E-36 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 89 3.1E-47 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.4E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.4E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.4E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 26.293 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15120 8bb262ec9b08926c997881a7b1dd2a0e 94 Pfam PF00203 Ribosomal protein S19 3 83 2.4E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS02605 622086708414f9574a5cae2f478d1985 161 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 10 124 2.4E-35 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 HVS_RS02605 622086708414f9574a5cae2f478d1985 161 SUPERFAMILY SSF51735 8 119 1.5E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS02605 622086708414f9574a5cae2f478d1985 161 Gene3D G3DSA:3.40.50.720 9 137 1.8E-24 T 29-03-2018 HVS_RS02605 622086708414f9574a5cae2f478d1985 161 Pfam PF13241 Putative NAD(P)-binding 12 121 4.4E-34 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 HVS_RS08095 0e9683a0baaf72dbf56ce66ca8129595 144 Gene3D G3DSA:3.40.1510.10 13 144 2.1E-43 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP HVS_RS08095 0e9683a0baaf72dbf56ce66ca8129595 144 Pfam PF09021 HutP 16 142 3.6E-49 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP HVS_RS03615 f4c122e6d5448d6e07e4e9b46cc686da 431 SUPERFAMILY SSF69304 191 421 3.01E-10 T 29-03-2018 HVS_RS03615 f4c122e6d5448d6e07e4e9b46cc686da 431 Gene3D G3DSA:2.120.10.60 294 426 0.012 T 29-03-2018 HVS_RS03615 f4c122e6d5448d6e07e4e9b46cc686da 431 Gene3D G3DSA:2.120.10.60 79 292 7.1E-7 T 29-03-2018 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 Gene3D G3DSA:3.20.20.80 34 334 8.0E-53 T 29-03-2018 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 52 298 1.0E-59 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 SMART SM00606 370 493 1.7E-34 T 29-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 Pfam PF03422 Carbohydrate binding module (family 6) 378 492 1.4E-32 T 29-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 541 560 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 SUPERFAMILY SSF49785 370 492 8.5E-38 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 505 524 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 Gene3D G3DSA:1.10.1330.10 501 567 8.9E-5 T 29-03-2018 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 Pfam PF00404 Dockerin type I repeat 505 525 9.0E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 SUPERFAMILY SSF63446 501 566 5.89E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 ProSitePatterns PS00018 EF-hand calcium-binding domain. 505 517 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 SUPERFAMILY SSF51445 42 340 3.32E-88 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 164 173 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 HVS_RS12220 52f638d79ff2c99ed43ad1fe9e42e864 567 Gene3D G3DSA:2.60.120.260 335 500 2.7E-36 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS05145 83c7a8a1bb367d71136e96fd117d595e 455 Pfam PF17202 Single cache domain 3 78 181 1.2E-24 T 29-03-2018 IPR033463 Single cache domain 3 HVS_RS05145 83c7a8a1bb367d71136e96fd117d595e 455 Pfam PF17202 Single cache domain 3 309 405 6.9E-25 T 29-03-2018 IPR033463 Single cache domain 3 HVS_RS05145 83c7a8a1bb367d71136e96fd117d595e 455 SUPERFAMILY SSF103190 110 182 1.26E-8 T 29-03-2018 IPR029151 Periplasmic sensor domain-like HVS_RS05145 83c7a8a1bb367d71136e96fd117d595e 455 Gene3D G3DSA:3.30.450.20 302 407 9.8E-6 T 29-03-2018 HVS_RS05145 83c7a8a1bb367d71136e96fd117d595e 455 Gene3D G3DSA:3.30.450.20 73 183 0.0024 T 29-03-2018 HVS_RS05145 83c7a8a1bb367d71136e96fd117d595e 455 SUPERFAMILY SSF103190 320 404 1.18E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like HVS_RS03170 6f115bbf25c781ad3c0b12db1b26ba55 238 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 220 2.3E-58 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 HVS_RS03170 6f115bbf25c781ad3c0b12db1b26ba55 238 Gene3D G3DSA:3.30.420.40 1 101 1.3E-15 T 29-03-2018 HVS_RS03170 6f115bbf25c781ad3c0b12db1b26ba55 238 Pfam PF00814 Glycoprotease family 32 225 1.5E-32 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HVS_RS03170 6f115bbf25c781ad3c0b12db1b26ba55 238 Gene3D G3DSA:3.30.420.40 102 182 4.2E-20 T 29-03-2018 HVS_RS03170 6f115bbf25c781ad3c0b12db1b26ba55 238 SUPERFAMILY SSF53067 109 218 2.72E-16 T 29-03-2018 HVS_RS03170 6f115bbf25c781ad3c0b12db1b26ba55 238 SUPERFAMILY SSF53067 1 103 7.34E-29 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 Gene3D G3DSA:2.30.38.10 379 452 1.5E-18 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 SUPERFAMILY SSF56801 15 291 1.44E-104 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 SUPERFAMILY SSF56801 326 566 1.44E-104 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 Gene3D G3DSA:3.30.300.30 453 570 5.3E-12 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 Gene3D G3DSA:3.40.50.980 12 193 4.5E-26 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 Gene3D G3DSA:3.40.50.980 194 378 1.8E-36 T 29-03-2018 HVS_RS02125 934d7ebea129ce9f5a49e437884cefa7 570 Pfam PF00501 AMP-binding enzyme 22 460 2.1E-78 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HVS_RS10990 33e783fcb2a1090fd39a94b051ac40dc 425 Gene3D G3DSA:3.40.50.620 1 256 1.4E-62 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS10990 33e783fcb2a1090fd39a94b051ac40dc 425 Pfam PF05636 HIGH Nucleotidyl Transferase 1 411 1.0E-144 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 HVS_RS10990 33e783fcb2a1090fd39a94b051ac40dc 425 SUPERFAMILY SSF52374 1 107 2.09E-22 T 29-03-2018 HVS_RS10990 33e783fcb2a1090fd39a94b051ac40dc 425 SUPERFAMILY SSF52374 162 249 2.09E-22 T 29-03-2018 HVS_RS10990 33e783fcb2a1090fd39a94b051ac40dc 425 Hamap MF_01539 UPF0348 protein . 2 423 36.752 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 HVS_RS08115 c764a5effdd3e7dfe85d7037c27da68c 56 Pfam PF14084 Protein of unknown function (DUF4264) 6 55 5.6E-20 T 29-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA HVS_RS08660 9c51e07e81e47954f01665f2e0242a6c 403 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 76 395 6.4E-99 T 29-03-2018 IPR014194 Sporulation stage III, protein AE HVS_RS08660 9c51e07e81e47954f01665f2e0242a6c 403 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 13 395 9.0E-94 T 29-03-2018 IPR014194 Sporulation stage III, protein AE HVS_RS13200 51cd7545a8cdd1b626e6bfba193f1715 241 SUPERFAMILY SSF52096 13 190 1.04E-47 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS13200 51cd7545a8cdd1b626e6bfba193f1715 241 PRINTS PR00127 Clp protease catalytic subunit P signature 164 183 8.9E-9 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS13200 51cd7545a8cdd1b626e6bfba193f1715 241 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 8.9E-9 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS13200 51cd7545a8cdd1b626e6bfba193f1715 241 PRINTS PR00127 Clp protease catalytic subunit P signature 88 105 8.9E-9 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS13200 51cd7545a8cdd1b626e6bfba193f1715 241 Gene3D G3DSA:3.90.226.10 8 189 1.1E-26 T 29-03-2018 HVS_RS13200 51cd7545a8cdd1b626e6bfba193f1715 241 Pfam PF00574 Clp protease 51 186 1.7E-31 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HVS_RS02040 8fa9d206039c8a62e56dca19faac3133 394 Pfam PF02371 Transposase IS116/IS110/IS902 family 260 349 1.6E-22 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HVS_RS02040 8fa9d206039c8a62e56dca19faac3133 394 Pfam PF01548 Transposase 2 153 3.9E-17 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HVS_RS12320 61589674303c8d640a74c6ef66da6bf6 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 279 4.0E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS12320 61589674303c8d640a74c6ef66da6bf6 292 SUPERFAMILY SSF161098 25 292 6.67E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS12320 61589674303c8d640a74c6ef66da6bf6 292 Gene3D G3DSA:1.10.3720.10 14 279 1.0E-33 T 29-03-2018 HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 72 243 1.2E-8 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:1.50.10.20 221 307 1.2E-7 T 29-03-2018 HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:1.50.10.20 151 220 3.6E-12 T 29-03-2018 HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:2.60.40.10 937 1036 2.8E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:2.60.40.10 830 932 4.9E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:2.60.40.10 1057 1152 0.15 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Pfam PF00092 von Willebrand factor type A domain 555 709 1.1E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 SUPERFAMILY SSF48239 124 303 3.14E-30 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 SUPERFAMILY SSF48239 34 92 3.14E-30 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:2.60.40.10 1189 1307 5.5E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1198 1239 1.0E-5 T 29-03-2018 IPR001434 Domain of unknown function DUF11 HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 SUPERFAMILY SSF53300 551 720 2.09E-37 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:1.50.10.20 24 150 3.9E-12 T 29-03-2018 HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Gene3D G3DSA:3.40.50.410 545 729 1.8E-39 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 SMART SM00327 553 716 9.0E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Pfam PF00395 S-layer homology domain 1422 1462 4.6E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Pfam PF00395 S-layer homology domain 1321 1342 4.0E-5 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS00860 99d2497e5f38803a145a91e7f83e07e0 1525 Pfam PF00395 S-layer homology domain 1361 1402 4.7E-15 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14060 d00ace50a0dba11e1f7537449ea70ab4 336 Pfam PF04245 37-kD nucleoid-associated bacterial protein 11 329 4.3E-50 T 29-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 Gene3D G3DSA:3.30.930.10 8 254 7.6E-91 T 29-03-2018 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 Gene3D G3DSA:3.30.980.10 563 723 1.7E-41 T 29-03-2018 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 663 705 1.2E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 SUPERFAMILY SSF55186 562 726 2.09E-47 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 1.3E-13 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 238 251 1.3E-13 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 1.3E-13 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 SUPERFAMILY SSF50447 463 562 1.8E-17 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 SMART SM00863 663 706 2.2E-17 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 122.21 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 SUPERFAMILY SSF55681 10 257 3.15E-76 T 29-03-2018 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 13 857 7.0E-234 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 Pfam PF02272 DHHA1 domain 765 874 5.1E-11 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 SUPERFAMILY SSF101353 258 440 1.44E-43 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 HVS_RS12415 99910df04418673e0ae88199fa390d3f 877 Pfam PF01411 tRNA synthetases class II (A) 13 566 6.6E-154 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 HVS_RS00125 f6d723803f8237b87e97b22448f1b41a 311 Gene3D G3DSA:3.40.50.970 98 311 7.9E-48 T 29-03-2018 HVS_RS00125 f6d723803f8237b87e97b22448f1b41a 311 Gene3D G3DSA:3.40.50.970 2 97 2.2E-26 T 29-03-2018 HVS_RS00125 f6d723803f8237b87e97b22448f1b41a 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 218 2.4E-24 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS00125 f6d723803f8237b87e97b22448f1b41a 311 SUPERFAMILY SSF52518 11 309 4.91E-76 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS11765 fc7c5e9826b1b0aa1186285343c25ad4 508 Pfam PF00942 Cellulose binding domain 364 445 1.1E-14 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS11765 fc7c5e9826b1b0aa1186285343c25ad4 508 SMART SM01067 364 446 2.6E-12 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS11765 fc7c5e9826b1b0aa1186285343c25ad4 508 SUPERFAMILY SSF49384 359 507 1.31E-36 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS11765 fc7c5e9826b1b0aa1186285343c25ad4 508 Pfam PF12791 Anti-sigma factor N-terminus 11 62 1.5E-12 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS11765 fc7c5e9826b1b0aa1186285343c25ad4 508 Gene3D G3DSA:2.60.40.710 350 508 5.5E-37 T 29-03-2018 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 HVS_RS14990 c260d48f154bc16f836289231ded18af 174 SUPERFAMILY SSF64263 3 56 1.15E-34 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS14990 c260d48f154bc16f836289231ded18af 174 SUPERFAMILY SSF64263 110 174 1.15E-34 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS14990 c260d48f154bc16f836289231ded18af 174 Pfam PF01196 Ribosomal protein L17 17 174 3.0E-34 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS14990 c260d48f154bc16f836289231ded18af 174 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 2 174 26.374 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS14990 c260d48f154bc16f836289231ded18af 174 Gene3D G3DSA:3.90.1030.10 2 174 5.8E-42 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS01525 dbad263dc436c723bc9d2da2c2e2f1ea 527 Pfam PF01420 Type I restriction modification DNA specificity domain 341 495 2.8E-15 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HVS_RS01525 dbad263dc436c723bc9d2da2c2e2f1ea 527 Gene3D G3DSA:3.40.50.150 125 301 4.1E-13 T 29-03-2018 HVS_RS01525 dbad263dc436c723bc9d2da2c2e2f1ea 527 Gene3D G3DSA:3.90.220.20 327 490 2.0E-32 T 29-03-2018 HVS_RS01525 dbad263dc436c723bc9d2da2c2e2f1ea 527 Pfam PF02384 N-6 DNA Methylase 97 298 4.7E-10 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HVS_RS01525 dbad263dc436c723bc9d2da2c2e2f1ea 527 SUPERFAMILY SSF53335 48 304 5.5E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS01525 dbad263dc436c723bc9d2da2c2e2f1ea 527 SUPERFAMILY SSF116734 342 513 5.23E-32 T 29-03-2018 HVS_RS02525 ac6400832834e9fd7b5b33cac5ea2cb6 286 SMART SM00460 199 261 8.2E-14 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS02525 ac6400832834e9fd7b5b33cac5ea2cb6 286 Pfam PF01841 Transglutaminase-like superfamily 148 258 3.3E-22 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS02525 ac6400832834e9fd7b5b33cac5ea2cb6 286 SUPERFAMILY SSF54001 100 272 2.24E-28 T 29-03-2018 HVS_RS02525 ac6400832834e9fd7b5b33cac5ea2cb6 286 Gene3D G3DSA:3.90.260.10 125 274 0.0058 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS06460 5ac69c62f2ad25d16e8b7517a4f70e24 285 SUPERFAMILY SSF55729 139 282 2.06E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS06460 5ac69c62f2ad25d16e8b7517a4f70e24 285 Pfam PF00583 Acetyltransferase (GNAT) family 146 239 1.6E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS06460 5ac69c62f2ad25d16e8b7517a4f70e24 285 Gene3D G3DSA:3.40.630.30 106 284 6.8E-15 T 29-03-2018 HVS_RS06460 5ac69c62f2ad25d16e8b7517a4f70e24 285 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 21 282 1.9E-85 T 29-03-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 HVS_RS06460 5ac69c62f2ad25d16e8b7517a4f70e24 285 Gene3D G3DSA:3.40.630.30 38 105 6.3E-4 T 29-03-2018 HVS_RS04715 a96d3e0c26aff332eb5e9b3bba2cd9a1 463 Pfam PF13546 DDE superfamily endonuclease 77 286 2.3E-16 T 29-03-2018 HVS_RS04715 a96d3e0c26aff332eb5e9b3bba2cd9a1 463 Gene3D G3DSA:3.90.350.10 98 360 1.8E-31 T 29-03-2018 IPR014736 Transposase, Tn5-like, core HVS_RS04715 a96d3e0c26aff332eb5e9b3bba2cd9a1 463 SUPERFAMILY SSF53098 74 422 2.88E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01585 a96d3e0c26aff332eb5e9b3bba2cd9a1 463 Pfam PF13546 DDE superfamily endonuclease 77 286 2.3E-16 T 29-03-2018 HVS_RS01585 a96d3e0c26aff332eb5e9b3bba2cd9a1 463 Gene3D G3DSA:3.90.350.10 98 360 1.8E-31 T 29-03-2018 IPR014736 Transposase, Tn5-like, core HVS_RS01585 a96d3e0c26aff332eb5e9b3bba2cd9a1 463 SUPERFAMILY SSF53098 74 422 2.88E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 PIRSF PIRSF020967 10 87 7.2E-10 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 PIRSF PIRSF020967 102 273 5.1E-24 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 PIRSF PIRSF020967 332 474 4.4E-14 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 Gene3D G3DSA:3.40.50.2020 26 263 1.9E-14 T 29-03-2018 HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 SUPERFAMILY SSF53271 118 236 2.84E-8 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 Pfam PF12500 TRSP domain C terminus to PRTase_2 338 463 6.6E-37 T 29-03-2018 IPR022537 TRSP domain HVS_RS07930 d5e82aa78e9862f02b0c08960d036d62 477 Pfam PF15609 Phosphoribosyl transferase 39 259 6.5E-66 T 29-03-2018 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 393 20.352 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 386 8.8E-72 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 153 2.7E-41 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 SUPERFAMILY SSF51735 169 328 1.73E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 SUPERFAMILY SSF69742 3 153 5.62E-39 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 Gene3D G3DSA:3.40.50.720 157 317 1.0E-13 T 29-03-2018 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 PIRSF PIRSF000445 1 393 5.8E-85 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 HVS_RS02600 ce1970243a6b60b9fd8bf5bb0bcff3ca 394 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 295 2.0E-19 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 6 306 8.9E-120 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 Gene3D G3DSA:3.40.50.450 1 187 4.6E-70 T 29-03-2018 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PIRSF PIRSF000532 3 325 5.8E-117 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 ProSitePatterns PS00433 Phosphofructokinase signature. 250 268 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 Pfam PF00365 Phosphofructokinase 6 282 2.3E-103 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 4 325 44.484 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 SUPERFAMILY SSF53784 2 323 3.4E-112 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 Gene3D G3DSA:3.40.50.450 194 307 7.2E-19 T 29-03-2018 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 141 159 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 246 268 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 96 112 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 9 28 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 34 47 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 161 177 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 179 196 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 123 140 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS10715 25dfd64a8e05e33069944268227e52d6 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 218 230 3.6E-82 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 HVS_RS15820 95108e4735d7979d76d0bc2689d002a5 99 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 HVS_RS15820 95108e4735d7979d76d0bc2689d002a5 99 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 1.6E-37 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID HVS_RS15820 95108e4735d7979d76d0bc2689d002a5 99 Pfam PF12116 Stage III sporulation protein D 2 82 7.7E-40 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID HVS_RS15820 95108e4735d7979d76d0bc2689d002a5 99 Gene3D G3DSA:1.10.10.10 1 81 2.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11585 03fd2e485566d931c2bf593fb0b50654 358 Gene3D G3DSA:3.50.90.10 48 358 4.3E-92 T 29-03-2018 IPR023158 YerB-like HVS_RS11585 03fd2e485566d931c2bf593fb0b50654 358 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 235 346 2.3E-32 T 29-03-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain HVS_RS11585 03fd2e485566d931c2bf593fb0b50654 358 SUPERFAMILY SSF159774 75 357 3.27E-79 T 29-03-2018 IPR023158 YerB-like HVS_RS11585 03fd2e485566d931c2bf593fb0b50654 358 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 75 206 7.7E-35 T 29-03-2018 IPR021416 Protein of unknown function DUF3048, N-terminal HVS_RS05065 1daa39177bc1324cdd265c6325cd824e 211 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 20 205 6.7E-24 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like HVS_RS05065 1daa39177bc1324cdd265c6325cd824e 211 Gene3D G3DSA:3.30.70.100 107 191 1.6E-4 T 29-03-2018 HVS_RS11970 3656e1613c8ea9b47ccc067ba61b5e6a 272 Gene3D G3DSA:1.10.3720.10 26 271 1.2E-22 T 29-03-2018 HVS_RS11970 3656e1613c8ea9b47ccc067ba61b5e6a 272 SUPERFAMILY SSF161098 75 256 5.49E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS11970 3656e1613c8ea9b47ccc067ba61b5e6a 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 269 4.5E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 Gene3D G3DSA:1.10.10.10 229 301 6.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 SUPERFAMILY SSF46785 233 297 7.62E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 PRINTS PR00502 NUDIX hydrolase family signature 70 84 2.3E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 PRINTS PR00502 NUDIX hydrolase family signature 84 99 2.3E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 Pfam PF00293 NUDIX domain 55 149 5.0E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 Gene3D G3DSA:3.90.79.10 24 228 1.3E-38 T 29-03-2018 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 SUPERFAMILY SSF55811 15 151 9.07E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 PIRSF PIRSF019423 172 303 7.4E-18 T 29-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein HVS_RS13960 8fd6ec1145e6044aa88a52bc06ae3a9f 303 PIRSF PIRSF019423 36 162 3.8E-7 T 29-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 PIRSF PIRSF006630 3 637 1.1E-152 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 Pfam PF00795 Carbon-nitrogen hydrolase 17 273 6.7E-16 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 Gene3D G3DSA:3.60.110.10 1 344 7.6E-73 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 SUPERFAMILY SSF56317 4 285 9.29E-43 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 Gene3D G3DSA:3.40.50.620 345 638 1.4E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 SUPERFAMILY SSF52402 316 617 8.15E-70 T 29-03-2018 HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 TIGRFAM TIGR00552 nadE: NAD+ synthetase 341 504 2.4E-26 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 HVS_RS02630 281b0f90bc64d220098d47c8163572b9 643 Pfam PF02540 NAD synthase 339 565 3.4E-31 T 29-03-2018 IPR022310 NAD/GMP synthase HVS_RS07890 d2c15a05787664b14703b1d8d31398f5 400 PIRSF PIRSF026508 20 400 3.0E-99 T 29-03-2018 IPR008863 Toxic anion resistance HVS_RS07890 d2c15a05787664b14703b1d8d31398f5 400 Pfam PF05816 Toxic anion resistance protein (TelA) 64 394 5.6E-109 T 29-03-2018 IPR008863 Toxic anion resistance HVS_RS15495 07fef67d4c1de679a3a62ca24eb4fb7e 317 Pfam PF00395 S-layer homology domain 144 185 1.6E-14 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS15495 07fef67d4c1de679a3a62ca24eb4fb7e 317 Pfam PF00395 S-layer homology domain 204 245 4.3E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01125 97a8c9a76ba72901f3dcc90a5262e781 146 SUPERFAMILY SSF56024 5 138 1.41E-13 T 29-03-2018 HVS_RS01125 97a8c9a76ba72901f3dcc90a5262e781 146 Gene3D G3DSA:3.30.870.10 1 145 3.1E-15 T 29-03-2018 HVS_RS01125 97a8c9a76ba72901f3dcc90a5262e781 146 Pfam PF13091 PLD-like domain 19 133 3.6E-17 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 HVS_RS02935 d7df22364bfef12bcc2e29271771e266 278 Pfam PF01261 Xylose isomerase-like TIM barrel 20 212 5.9E-24 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS02935 d7df22364bfef12bcc2e29271771e266 278 SUPERFAMILY SSF51658 11 269 4.19E-34 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS02935 d7df22364bfef12bcc2e29271771e266 278 Gene3D G3DSA:3.20.20.150 7 274 9.9E-35 T 29-03-2018 HVS_RS00500 054133cd4d77787a5641bb14393fff26 122 Pfam PF10135 Rod binding protein 64 112 3.8E-13 T 29-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal HVS_RS00500 054133cd4d77787a5641bb14393fff26 122 Gene3D G3DSA:1.10.1740.10 23 79 0.0011 T 29-03-2018 HVS_RS00500 054133cd4d77787a5641bb14393fff26 122 ProDom PD351196 CJ1463 JHP0230 HP0245 32 110 0.001 T 29-03-2018 HVS_RS01565 ab810e495affd16128a70ba1e5995285 228 SUPERFAMILY SSF52540 74 205 6.28E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01565 ab810e495affd16128a70ba1e5995285 228 Gene3D G3DSA:3.40.50.300 41 222 1.6E-13 T 29-03-2018 HVS_RS01565 ab810e495affd16128a70ba1e5995285 228 PIRSF PIRSF003073 3 228 2.7E-41 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS01565 ab810e495affd16128a70ba1e5995285 228 Pfam PF01695 IstB-like ATP binding protein 47 223 9.4E-30 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 SUPERFAMILY SSF63446 27 92 2.55E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 Pfam PF00404 Dockerin type I repeat 63 83 3.0E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 Gene3D G3DSA:1.10.1330.10 28 93 6.6E-5 T 29-03-2018 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 122 320 1.2E-52 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 320 450 2.0E-21 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 432 564 1.2E-18 T 29-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 ProSitePatterns PS00018 EF-hand calcium-binding domain. 31 43 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS12820 3962bc6c46dd538cf54e16006ab1169e 727 Gene3D G3DSA:2.160.20.20 207 679 5.7E-7 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like HVS_RS09820 15e55ec4591a0a7ec5f31ffd30e04feb 303 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 88 2.3E-7 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 HVS_RS09820 15e55ec4591a0a7ec5f31ffd30e04feb 303 Gene3D G3DSA:3.40.50.720 1 116 8.0E-12 T 29-03-2018 HVS_RS09820 15e55ec4591a0a7ec5f31ffd30e04feb 303 Gene3D G3DSA:3.30.360.10 117 303 4.9E-18 T 29-03-2018 HVS_RS09820 15e55ec4591a0a7ec5f31ffd30e04feb 303 SUPERFAMILY SSF55347 110 251 9.48E-14 T 29-03-2018 HVS_RS09820 15e55ec4591a0a7ec5f31ffd30e04feb 303 SUPERFAMILY SSF51735 155 176 3.4E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09820 15e55ec4591a0a7ec5f31ffd30e04feb 303 SUPERFAMILY SSF51735 1 125 3.4E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09040 fa82617bc1a491deee72198b47a8686f 472 Pfam PF04616 Glycosyl hydrolases family 43 26 315 5.6E-26 T 29-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 HVS_RS09040 fa82617bc1a491deee72198b47a8686f 472 Gene3D G3DSA:2.115.10.20 4 323 8.2E-49 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS09040 fa82617bc1a491deee72198b47a8686f 472 SUPERFAMILY SSF75005 7 323 3.99E-44 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS09040 fa82617bc1a491deee72198b47a8686f 472 Gene3D G3DSA:2.60.120.260 350 472 4.0E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS02970 8ab3829cd0b06ba0be00d61e08bd2891 115 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 29 82 2.5E-5 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 HVS_RS02970 8ab3829cd0b06ba0be00d61e08bd2891 115 SUPERFAMILY SSF143011 21 79 1.35E-8 T 29-03-2018 IPR035095 Toxin RelE-like domain HVS_RS02970 8ab3829cd0b06ba0be00d61e08bd2891 115 Gene3D G3DSA:3.30.2310.20 2 106 3.0E-17 T 29-03-2018 HVS_RS10325 4637ee79ee26fc251edfe71d6e6e89de 298 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 1 297 3.2E-73 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 HVS_RS10325 4637ee79ee26fc251edfe71d6e6e89de 298 PIRSF PIRSF018571 1 298 5.4E-100 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 HVS_RS10325 4637ee79ee26fc251edfe71d6e6e89de 298 Pfam PF03419 Sporulation factor SpoIIGA 2 297 9.8E-90 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 SUPERFAMILY SSF50486 199 305 5.18E-30 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 300 33.98 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 127 150 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 Gene3D G3DSA:3.10.25.10 202 306 1.0E-29 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 Pfam PF00551 Formyl transferase 15 174 1.4E-40 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 297 4.4E-97 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 Pfam PF02911 Formyl transferase, C-terminal domain 199 297 2.2E-26 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 Gene3D G3DSA:3.40.50.170 1 200 8.0E-70 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS07035 1195678ca412bb5d8d5ca77c221bcd16 306 SUPERFAMILY SSF53328 1 201 4.58E-67 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 Pfam PF13623 SurA N-terminal domain 7 147 1.5E-7 T 29-03-2018 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 Gene3D G3DSA:1.25.40.10 322 447 7.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 SUPERFAMILY SSF48452 331 443 6.01E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 SUPERFAMILY SSF54534 186 287 1.57E-19 T 29-03-2018 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 Pfam PF00639 PPIC-type PPIASE domain 194 284 6.0E-17 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 SUPERFAMILY SSF109998 72 218 1.33E-13 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 Gene3D G3DSA:1.10.4030.10 43 159 5.0E-9 T 29-03-2018 HVS_RS12350 ab171397a17bc4bd7b46a49c01ee7547 449 Gene3D G3DSA:3.10.50.40 179 321 3.6E-22 T 29-03-2018 HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 Gene3D G3DSA:1.10.10.10 103 204 3.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 Pfam PF04545 Sigma-70, region 4 151 199 9.3E-11 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 SUPERFAMILY SSF88659 134 202 1.03E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 SUPERFAMILY SSF88946 38 112 6.12E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 Pfam PF04542 Sigma-70 region 2 39 106 1.9E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 Gene3D G3DSA:1.10.1740.10 31 102 3.1E-22 T 29-03-2018 HVS_RS00305 37ab3246a7dba1847763a1e142faae10 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 201 9.7E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 349 357 3.8E-20 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 408 3.8E-20 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 381 3.8E-20 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 3.8E-20 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 427 3.8E-20 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 SUPERFAMILY SSF51445 5 445 6.12E-171 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 349 357 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 Pfam PF00232 Glycosyl hydrolase family 1 5 445 8.5E-181 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 437 2.3E-186 T 29-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 HVS_RS11370 2eb35cdc7d981ec77ba9b2eff63e1627 446 Gene3D G3DSA:3.20.20.80 2 446 2.3E-171 T 29-03-2018 HVS_RS02225 6481079fef935885ca701fcebcf7766b 75 Pfam PF00403 Heavy-metal-associated domain 5 68 1.8E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HVS_RS02225 6481079fef935885ca701fcebcf7766b 75 Gene3D G3DSA:3.30.70.100 1 74 1.0E-16 T 29-03-2018 HVS_RS02225 6481079fef935885ca701fcebcf7766b 75 SUPERFAMILY SSF55008 1 70 8.12E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HVS_RS12575 ac82345e78e6e34c500939ad5f4c68f4 154 Gene3D G3DSA:3.40.1550.10 1 154 2.8E-31 T 29-03-2018 IPR028976 CheC-like domain HVS_RS12575 ac82345e78e6e34c500939ad5f4c68f4 154 Pfam PF13690 Chemotaxis phosphatase CheX 46 121 8.8E-13 T 29-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain HVS_RS12575 ac82345e78e6e34c500939ad5f4c68f4 154 SUPERFAMILY SSF103039 1 150 1.83E-30 T 29-03-2018 IPR028976 CheC-like domain HVS_RS05185 4bd85d6abad24e49149ed75d78d6d629 200 SUPERFAMILY SSF53335 1 165 8.82E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS05185 4bd85d6abad24e49149ed75d78d6d629 200 Pfam PF13649 Methyltransferase domain 3 97 6.8E-13 T 29-03-2018 HVS_RS05185 4bd85d6abad24e49149ed75d78d6d629 200 Gene3D G3DSA:3.40.50.150 1 185 4.3E-26 T 29-03-2018 HVS_RS02755 8cfe2a3c25c9572ab1c4350e434c9968 277 Pfam PF00005 ABC transporter 20 152 2.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS02755 8cfe2a3c25c9572ab1c4350e434c9968 277 SMART SM00382 29 201 1.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02755 8cfe2a3c25c9572ab1c4350e434c9968 277 SUPERFAMILY SSF52540 4 204 5.61E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02755 8cfe2a3c25c9572ab1c4350e434c9968 277 Gene3D G3DSA:3.40.50.300 1 216 6.6E-47 T 29-03-2018 HVS_RS07975 ac79c313a44cdbd00bd370d0d7c0cdf2 221 SUPERFAMILY SSF53323 4 193 2.75E-36 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HVS_RS07975 ac79c313a44cdbd00bd370d0d7c0cdf2 221 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 6 185 1.5E-36 T 29-03-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 HVS_RS07975 ac79c313a44cdbd00bd370d0d7c0cdf2 221 Gene3D G3DSA:3.40.920.10 1 220 3.5E-51 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS07975 ac79c313a44cdbd00bd370d0d7c0cdf2 221 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 211 1.2E-38 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS06565 dd8b57cd469915984ebbe484f6f171e0 74 Pfam PF08845 Toxin SymE, type I toxin-antitoxin system 8 50 1.1E-10 T 29-03-2018 IPR014944 Toxin SymE-like GO:0003723|GO:0005737|GO:0016070|GO:0016788 HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 Gene3D G3DSA:3.30.70.20 1 19 2.8E-7 T 29-03-2018 HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 Gene3D G3DSA:3.30.70.20 20 42 7.0E-11 T 29-03-2018 HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 Gene3D G3DSA:3.30.70.20 43 65 4.5E-6 T 29-03-2018 HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 SUPERFAMILY SSF54862 2 60 6.8E-16 T 29-03-2018 HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS03570 abb7947e6c939be8fc8e215154bb7738 65 Pfam PF14697 4Fe-4S dicluster domain 4 56 5.2E-11 T 29-03-2018 HVS_RS07965 901c9d321c5b311de3b30d4995c10881 384 SUPERFAMILY SSF52518 20 268 5.35E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS07965 901c9d321c5b311de3b30d4995c10881 384 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 276 356 4.1E-17 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II HVS_RS07965 901c9d321c5b311de3b30d4995c10881 384 Gene3D G3DSA:3.40.50.970 18 271 4.7E-33 T 29-03-2018 HVS_RS07965 901c9d321c5b311de3b30d4995c10881 384 SUPERFAMILY SSF52922 272 382 5.76E-21 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS07965 901c9d321c5b311de3b30d4995c10881 384 Gene3D G3DSA:3.40.50.920 272 382 3.6E-17 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HVS_RS07965 901c9d321c5b311de3b30d4995c10881 384 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 32 249 1.2E-55 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 HVS_RS07005 a0c47569ba47583031e92ecda80b56fe 223 Pfam PF00436 Single-strand binding protein family 111 206 7.3E-17 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HVS_RS07005 a0c47569ba47583031e92ecda80b56fe 223 Gene3D G3DSA:2.40.50.140 104 210 3.3E-25 T 29-03-2018 HVS_RS07005 a0c47569ba47583031e92ecda80b56fe 223 Gene3D G3DSA:2.40.50.140 1 103 7.1E-11 T 29-03-2018 HVS_RS07005 a0c47569ba47583031e92ecda80b56fe 223 SUPERFAMILY SSF50249 9 208 9.52E-37 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 SMART SM00382 123 257 6.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 Pfam PF00437 Type II/IV secretion system protein 123 266 1.6E-37 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 Gene3D G3DSA:3.40.50.300 275 348 3.4E-12 T 29-03-2018 HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 Gene3D G3DSA:3.40.50.300 120 274 2.9E-24 T 29-03-2018 HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 SUPERFAMILY SSF52540 4 337 5.32E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 343 8.0E-143 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 HVS_RS11655 5aef1670bbada665b10c00271ed73bca 352 Gene3D G3DSA:3.30.450.90 2 101 5.2E-25 T 29-03-2018 HVS_RS12860 4d8b3a64a6617f2882ce90f8c92f892b 266 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 258 16.834 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HVS_RS12860 4d8b3a64a6617f2882ce90f8c92f892b 266 Pfam PF02673 Bacitracin resistance protein BacA 7 253 5.9E-73 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF00395 S-layer homology domain 1023 1065 2.9E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF00395 S-layer homology domain 962 1004 1.8E-9 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF00395 S-layer homology domain 903 942 1.3E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF12733 Cadherin-like beta sandwich domain 765 845 1.2E-18 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Gene3D G3DSA:3.40.50.410 200 387 2.5E-37 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 SMART SM00237 625 726 5.9E-24 T 29-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 SMART SM00327 206 386 2.6E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF08434 Calcium-activated chloride channel N terminal 49 184 1.6E-15 T 29-03-2018 IPR013642 Calcium-activated chloride channel, N-terminal Reactome: R-HSA-2672351 HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF03160 Calx-beta domain 632 725 2.0E-17 T 29-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 SUPERFAMILY SSF53300 193 385 3.56E-36 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 SUPERFAMILY SSF141072 636 744 5.36E-23 T 29-03-2018 HVS_RS04270 9667c0b26a4e74a15298e8e7c988850f 1079 Pfam PF00092 von Willebrand factor type A domain 208 375 1.9E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 Gene3D G3DSA:2.30.40.10 4 69 1.3E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 Pfam PF01979 Amidohydrolase family 52 388 6.9E-23 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 PIRSF PIRSF038994 3 392 1.3E-133 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 Gene3D G3DSA:3.20.20.140 70 360 2.8E-102 T 29-03-2018 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 SUPERFAMILY SSF51338 360 391 8.25E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 SUPERFAMILY SSF51338 6 56 8.25E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 387 1.9E-111 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 HVS_RS01175 344a03288cc96600ede0bd8b50a569e8 392 SUPERFAMILY SSF51556 56 360 4.56E-92 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS10995 605beb04cdcd1f0184ebc665e8370c82 245 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 43 197 2.4E-33 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS10995 605beb04cdcd1f0184ebc665e8370c82 245 SMART SM00283 11 244 1.8E-25 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS10995 605beb04cdcd1f0184ebc665e8370c82 245 Gene3D G3DSA:1.10.287.950 8 245 2.3E-43 T 29-03-2018 HVS_RS10995 605beb04cdcd1f0184ebc665e8370c82 245 SUPERFAMILY SSF58104 11 244 2.22E-53 T 29-03-2018 HVS_RS10995 605beb04cdcd1f0184ebc665e8370c82 245 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 96 125 1.1E-18 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS10995 605beb04cdcd1f0184ebc665e8370c82 245 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 67 94 1.1E-18 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 HVS_RS15945 afa971a4f45f1c22210c6dfa30e155bb 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 4.8E-95 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS15945 afa971a4f45f1c22210c6dfa30e155bb 418 SUPERFAMILY SSF55205 1 417 2.78E-133 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HVS_RS15945 afa971a4f45f1c22210c6dfa30e155bb 418 Gene3D G3DSA:3.65.10.10 221 418 1.4E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS15945 afa971a4f45f1c22210c6dfa30e155bb 418 Gene3D G3DSA:3.65.10.10 21 220 4.9E-45 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS15945 afa971a4f45f1c22210c6dfa30e155bb 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.6E-165 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS15945 afa971a4f45f1c22210c6dfa30e155bb 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 42.391 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 HVS_RS00850 81ee6f780da7d6d28b601da0b6b403be 235 SUPERFAMILY SSF50118 166 227 5.76E-13 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS00850 81ee6f780da7d6d28b601da0b6b403be 235 SUPERFAMILY SSF50118 64 114 5.76E-13 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS00850 81ee6f780da7d6d28b601da0b6b403be 235 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 66 228 1.1E-9 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 HVS_RS00850 81ee6f780da7d6d28b601da0b6b403be 235 Gene3D G3DSA:2.30.30.110 65 229 7.7E-25 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor HVS_RS13325 4b966bb4f3dc353262cf47989caca505 264 SUPERFAMILY SSF51261 95 236 5.75E-38 T 29-03-2018 IPR011055 Duplicated hybrid motif HVS_RS13325 4b966bb4f3dc353262cf47989caca505 264 Pfam PF01551 Peptidase family M23 125 228 7.4E-20 T 29-03-2018 IPR016047 Peptidase M23 HVS_RS13325 4b966bb4f3dc353262cf47989caca505 264 Gene3D G3DSA:2.70.70.10 68 241 3.5E-35 T 29-03-2018 HVS_RS06810 324f7b19e4490a6b41208aa2967f403a 345 Gene3D G3DSA:1.10.10.60 265 337 0.026 T 29-03-2018 HVS_RS06810 324f7b19e4490a6b41208aa2967f403a 345 Pfam PF04754 Putative transposase, YhgA-like 9 211 3.3E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS02465 34e4ebc828483a517b02f69740370888 147 SMART SM00240 71 121 1.7E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 HVS_RS02465 34e4ebc828483a517b02f69740370888 147 Pfam PF00498 FHA domain 73 138 4.9E-20 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 HVS_RS02465 34e4ebc828483a517b02f69740370888 147 SUPERFAMILY SSF49879 60 145 1.87E-27 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 HVS_RS02465 34e4ebc828483a517b02f69740370888 147 Gene3D G3DSA:2.60.200.20 31 146 2.5E-25 T 29-03-2018 HVS_RS10615 d93e5c7edcd413fd2d58d7d5dca3ab79 358 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 15 342 1.2E-80 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI HVS_RS10615 d93e5c7edcd413fd2d58d7d5dca3ab79 358 Pfam PF01594 AI-2E family transporter 16 343 2.7E-49 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 PRINTS PR00207 Flagellin signature 35 52 1.1E-23 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 PRINTS PR00207 Flagellin signature 109 132 1.1E-23 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 PRINTS PR00207 Flagellin signature 74 93 1.1E-23 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 SUPERFAMILY SSF64518 1 403 2.35E-105 T 29-03-2018 HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 8.5E-46 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 Gene3D G3DSA:1.20.1330.10 38 375 7.9E-78 T 29-03-2018 HVS_RS01410 a7380d3781355e57e28ffeadc57be7ae 403 Pfam PF00700 Bacterial flagellin C-terminal helical region 317 402 1.0E-28 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 HVS_RS03395 1b2c8ce93ebf6bb41bbf32fb4b34514c 194 SUPERFAMILY SSF53850 64 169 7.65E-34 T 29-03-2018 HVS_RS03395 1b2c8ce93ebf6bb41bbf32fb4b34514c 194 Pfam PF12849 PBP superfamily domain 59 169 1.0E-25 T 29-03-2018 IPR024370 PBP domain HVS_RS03395 1b2c8ce93ebf6bb41bbf32fb4b34514c 194 Gene3D G3DSA:3.40.190.10 64 182 1.8E-34 T 29-03-2018 HVS_RS02820 c8df06b2a98a0d43747e83eb80fd098d 680 Pfam PF13337 Putative ATP-dependent Lon protease 14 470 4.0E-211 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 HVS_RS02820 c8df06b2a98a0d43747e83eb80fd098d 680 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 12 461 2.8E-196 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 HVS_RS02820 c8df06b2a98a0d43747e83eb80fd098d 680 Gene3D G3DSA:3.30.230.10 495 678 1.3E-18 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS02820 c8df06b2a98a0d43747e83eb80fd098d 680 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 516 677 1.2E-7 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HVS_RS02820 c8df06b2a98a0d43747e83eb80fd098d 680 SUPERFAMILY SSF54211 499 679 6.45E-23 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS02820 c8df06b2a98a0d43747e83eb80fd098d 680 TIGRFAM TIGR02653 Lon_rel_chp: conserved hypothetical protein 6 679 0.0 T 29-03-2018 IPR013473 Conserved hypothetical protein CHP02653, peptidase S16 non-peptidase homologue HVS_RS05090 b0d2107e5dcfd795e5f62b671ff0306e 283 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 6 280 1.0E-54 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS05090 b0d2107e5dcfd795e5f62b671ff0306e 283 Pfam PF05582 YabG peptidase U57 6 281 7.1E-84 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS06325 089fd6582a668a0b7d9b54fbc639ae2a 373 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 50 369 2.1E-69 T 29-03-2018 IPR003770 Endolytic murein transglycosylase HVS_RS06325 089fd6582a668a0b7d9b54fbc639ae2a 373 Gene3D G3DSA:3.30.160.60 342 370 7.2E-12 T 29-03-2018 HVS_RS06325 089fd6582a668a0b7d9b54fbc639ae2a 373 Pfam PF02618 YceG-like family 70 367 9.8E-76 T 29-03-2018 IPR003770 Endolytic murein transglycosylase HVS_RS06325 089fd6582a668a0b7d9b54fbc639ae2a 373 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 25 372 31.038 T 29-03-2018 IPR003770 Endolytic murein transglycosylase HVS_RS03285 a3592ef0edf1bd308198ce12fd14b5d3 256 Gene3D G3DSA:2.60.120.260 26 201 1.3E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS03285 a3592ef0edf1bd308198ce12fd14b5d3 256 Pfam PF02018 Carbohydrate binding domain 31 164 8.3E-7 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS03285 a3592ef0edf1bd308198ce12fd14b5d3 256 SUPERFAMILY SSF49785 33 189 1.5E-7 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS13140 d9e9ab53f97fe80bb3975798a774f33b 257 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 3 130 4.5E-12 T 29-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal HVS_RS13140 d9e9ab53f97fe80bb3975798a774f33b 257 Pfam PF05709 Phage tail protein 25 257 5.5E-20 T 29-03-2018 IPR008841 Siphovirus-type tail component HVS_RS08575 4d3e35a3d7709e5913654513b0ececec 269 Gene3D G3DSA:3.40.50.150 2 266 5.8E-40 T 29-03-2018 HVS_RS08575 4d3e35a3d7709e5913654513b0ececec 269 Pfam PF13649 Methyltransferase domain 46 137 3.8E-20 T 29-03-2018 HVS_RS08575 4d3e35a3d7709e5913654513b0ececec 269 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 2 266 27.838 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 HVS_RS08575 4d3e35a3d7709e5913654513b0ececec 269 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 10 266 2.0E-64 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 HVS_RS08575 4d3e35a3d7709e5913654513b0ececec 269 SUPERFAMILY SSF53335 11 187 8.67E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS14225 e17c27a86dc58dc7eeaf0e6bccb59577 460 Pfam PF06782 Uncharacterised protein family (UPF0236) 3 458 6.0E-86 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS01945 e17c27a86dc58dc7eeaf0e6bccb59577 460 Pfam PF06782 Uncharacterised protein family (UPF0236) 3 458 6.0E-86 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS15200 e17c27a86dc58dc7eeaf0e6bccb59577 460 Pfam PF06782 Uncharacterised protein family (UPF0236) 3 458 6.0E-86 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS01740 58df9e2658c04a4cd677744883fb2cf2 156 Pfam PF09148 Domain of unknown function (DUF1934) 7 135 7.3E-37 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 HVS_RS01740 58df9e2658c04a4cd677744883fb2cf2 156 SUPERFAMILY SSF50814 1 141 5.5E-32 T 29-03-2018 IPR012674 Calycin HVS_RS01740 58df9e2658c04a4cd677744883fb2cf2 156 Gene3D G3DSA:2.40.128.20 1 144 9.3E-36 T 29-03-2018 IPR012674 Calycin HVS_RS07450 dd34ee0df69c64991b2c77d0a16ced7f 309 SUPERFAMILY SSF88659 8 47 4.11E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS07450 dd34ee0df69c64991b2c77d0a16ced7f 309 Gene3D G3DSA:1.10.10.60 2 49 6.4E-9 T 29-03-2018 HVS_RS10790 680f44ec99203262d3a4662bc42b6dd3 901 Pfam PF02687 FtsX-like permease family 800 890 2.3E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS10790 680f44ec99203262d3a4662bc42b6dd3 901 Pfam PF02687 FtsX-like permease family 307 406 4.7E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS11195 0da4655d5daa69fbe8fdd92aef901339 135 Gene3D G3DSA:2.40.50.140 1 111 4.8E-39 T 29-03-2018 HVS_RS11195 0da4655d5daa69fbe8fdd92aef901339 135 PIRSF PIRSF002070 1 134 1.1E-36 T 29-03-2018 HVS_RS11195 0da4655d5daa69fbe8fdd92aef901339 135 Hamap MF_00984 Single-stranded DNA-binding protein. 1 107 32.206 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HVS_RS11195 0da4655d5daa69fbe8fdd92aef901339 135 SUPERFAMILY SSF50249 1 135 1.37E-46 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS11195 0da4655d5daa69fbe8fdd92aef901339 135 Pfam PF00436 Single-strand binding protein family 1 102 4.2E-36 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 HVS_RS11195 0da4655d5daa69fbe8fdd92aef901339 135 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 119 1.3E-34 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 HVS_RS01030 8ea6b1b6889ee15e22656217ffd9dc58 128 Pfam PF05717 IS66 Orf2 like protein 21 116 9.3E-33 T 29-03-2018 IPR008878 Transposase IS66, Orf2 HVS_RS00975 8ea6b1b6889ee15e22656217ffd9dc58 128 Pfam PF05717 IS66 Orf2 like protein 21 116 9.3E-33 T 29-03-2018 IPR008878 Transposase IS66, Orf2 HVS_RS11210 b532f51f2ccc2a2b368e3d4808b994d3 312 SUPERFAMILY SSF102114 8 289 6.67E-41 T 29-03-2018 HVS_RS11210 b532f51f2ccc2a2b368e3d4808b994d3 312 Gene3D G3DSA:3.20.20.70 1 303 5.9E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS11210 b532f51f2ccc2a2b368e3d4808b994d3 312 SMART SM00729 19 247 6.9E-32 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS11210 b532f51f2ccc2a2b368e3d4808b994d3 312 Pfam PF16199 Radical_SAM C-terminal domain 209 291 2.7E-22 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 HVS_RS11210 b532f51f2ccc2a2b368e3d4808b994d3 312 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 2 302 6.9E-90 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 HVS_RS11210 b532f51f2ccc2a2b368e3d4808b994d3 312 Pfam PF04055 Radical SAM superfamily 32 195 2.8E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS07225 33e7778695ef218176d4390b7feb0fe2 167 Gene3D G3DSA:1.10.3210.10 10 161 4.8E-16 T 29-03-2018 HVS_RS07225 33e7778695ef218176d4390b7feb0fe2 167 Pfam PF01966 HD domain 37 142 8.5E-8 T 29-03-2018 IPR006674 HD domain HVS_RS07225 33e7778695ef218176d4390b7feb0fe2 167 SUPERFAMILY SSF109604 13 147 1.54E-19 T 29-03-2018 HVS_RS15370 9723d3cdb85bfeb3242f90a64e9414fa 70 PIRSF PIRSF037263 1 66 4.8E-32 T 29-03-2018 IPR009296 Protein of unknown function DUF951 HVS_RS15370 9723d3cdb85bfeb3242f90a64e9414fa 70 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 60 1.3E-30 T 29-03-2018 IPR009296 Protein of unknown function DUF951 HVS_RS06430 dbed52b5bb3d5f67d160ea4d7683a4bf 361 Pfam PF12725 Protein of unknown function (DUF3810) 34 355 2.3E-105 T 29-03-2018 IPR024294 Protein of unknown function DUF3810 HVS_RS03680 52d7ac7af714d45eb6087be078f5b430 288 Pfam PF00149 Calcineurin-like phosphoesterase 48 225 2.0E-16 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 HVS_RS03680 52d7ac7af714d45eb6087be078f5b430 288 Gene3D G3DSA:3.60.21.10 43 284 1.4E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS03680 52d7ac7af714d45eb6087be078f5b430 288 SUPERFAMILY SSF56300 48 286 4.38E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS05715 a9b3182ae8a15021b614def54f3487de 195 SUPERFAMILY SSF55383 51 134 2.48E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05715 a9b3182ae8a15021b614def54f3487de 195 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 1.8E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05715 a9b3182ae8a15021b614def54f3487de 195 Gene3D G3DSA:3.30.457.10 61 122 4.3E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05715 a9b3182ae8a15021b614def54f3487de 195 Gene3D G3DSA:3.30.457.10 8 60 2.1E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05715 a9b3182ae8a15021b614def54f3487de 195 Gene3D G3DSA:3.30.457.10 123 180 1.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 Gene3D G3DSA:4.10.870.10 598 653 1.2E-27 T 29-03-2018 IPR027390 Endoglucanase F, domain 3 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 328 347 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 74 99 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 210 234 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 100 117 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 608 636 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 396 419 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 497 517 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 255 282 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 PRINTS PR00844 Glycosyl hydrolase family 48 signature 442 468 8.2E-109 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 Pfam PF00404 Dockerin type I repeat 699 719 1.2E-4 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 Gene3D G3DSA:1.50.10.10 236 597 8.8E-142 T 29-03-2018 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 Gene3D G3DSA:1.50.10.10 51 222 4.7E-47 T 29-03-2018 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 SUPERFAMILY SSF63446 695 754 1.44E-13 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 Pfam PF02011 Glycosyl hydrolase family 48 52 675 2.1E-282 T 29-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 HVS_RS14560 8523d4b3c75d60620001b667cb8ce88b 761 SUPERFAMILY SSF48208 45 678 2.52E-281 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS01680 e0c2ae774c803af148ebbc55785ecda0 328 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 60 316 8.0E-94 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 HVS_RS01680 e0c2ae774c803af148ebbc55785ecda0 328 Pfam PF07136 Protein of unknown function (DUF1385) 60 319 9.8E-89 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 HVS_RS11975 84fa196e8dead3c46b701bf24858d3d0 255 Gene3D G3DSA:3.40.50.300 1 237 1.3E-58 T 29-03-2018 HVS_RS11975 84fa196e8dead3c46b701bf24858d3d0 255 SMART SM00382 33 214 9.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS11975 84fa196e8dead3c46b701bf24858d3d0 255 SUPERFAMILY SSF52540 4 222 3.14E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS11975 84fa196e8dead3c46b701bf24858d3d0 255 Pfam PF00005 ABC transporter 24 163 1.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS11975 84fa196e8dead3c46b701bf24858d3d0 255 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS01695 f2a3806bf3f3078c569b46516e588821 274 Gene3D G3DSA:3.30.457.10 70 132 1.8E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01695 f2a3806bf3f3078c569b46516e588821 274 Gene3D G3DSA:3.30.457.10 133 237 7.9E-11 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01695 f2a3806bf3f3078c569b46516e588821 274 Gene3D G3DSA:3.30.457.10 24 69 4.8E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01695 f2a3806bf3f3078c569b46516e588821 274 SUPERFAMILY SSF55383 61 145 1.57E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01695 f2a3806bf3f3078c569b46516e588821 274 Pfam PF07833 Copper amine oxidase N-terminal domain 58 150 1.9E-32 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07095 76780273db1c24b20ab962740a146668 585 Pfam PF05670 Domain of unknown function (DUF814) 467 552 3.4E-31 T 29-03-2018 IPR008532 Domain of unknown function DUF814 HVS_RS07095 76780273db1c24b20ab962740a146668 585 Gene3D G3DSA:2.30.310.10 1 166 2.3E-51 T 29-03-2018 HVS_RS07095 76780273db1c24b20ab962740a146668 585 Gene3D G3DSA:1.10.8.50 169 243 1.2E-11 T 29-03-2018 HVS_RS07095 76780273db1c24b20ab962740a146668 585 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 458 4.2E-153 T 29-03-2018 HVS_RS07095 76780273db1c24b20ab962740a146668 585 Gene3D G3DSA:3.40.970.40 252 303 1.3E-10 T 29-03-2018 HVS_RS07095 76780273db1c24b20ab962740a146668 585 SUPERFAMILY SSF46946 188 240 2.49E-7 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HVS_RS08625 651f2bedab196aa9b55d3cbc78d656c0 144 Gene3D G3DSA:1.10.940.10 1 143 5.4E-48 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HVS_RS08625 651f2bedab196aa9b55d3cbc78d656c0 144 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 133 23.863 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 HVS_RS08625 651f2bedab196aa9b55d3cbc78d656c0 144 SUPERFAMILY SSF48013 3 131 2.22E-41 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HVS_RS08625 651f2bedab196aa9b55d3cbc78d656c0 144 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 131 1.4E-45 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 HVS_RS08625 651f2bedab196aa9b55d3cbc78d656c0 144 Pfam PF01029 NusB family 5 130 6.5E-42 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 SUPERFAMILY SSF46589 1 112 3.56E-31 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 41.803 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.4E-30 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 SUPERFAMILY SSF55681 117 419 2.61E-99 T 29-03-2018 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 Gene3D G3DSA:1.10.287.40 2 104 3.7E-26 T 29-03-2018 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 PIRSF PIRSF001529 1 425 7.8E-184 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 2.2E-29 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 2.2E-29 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 2.2E-29 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 2.2E-29 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 2.2E-29 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 7.5E-174 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 399 9.8E-33 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 HVS_RS00055 b10c55a55fe31c96072e4c8683ffb559 427 Gene3D G3DSA:3.30.930.10 105 427 1.3E-94 T 29-03-2018 HVS_RS11400 28be1a78d780391d7f4cd27ace06ff36 276 Pfam PF12705 PD-(D/E)XK nuclease superfamily 14 248 4.1E-24 T 29-03-2018 HVS_RS02035 3204835d5e6bedd9a74f3d7617daebba 111 Gene3D G3DSA:1.10.1220.10 8 58 1.0E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 HVS_RS08280 72447f870a5530c8e93a4d6416f4516f 232 SMART SM00382 31 214 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08280 72447f870a5530c8e93a4d6416f4516f 232 SUPERFAMILY SSF52540 3 219 2.47E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08280 72447f870a5530c8e93a4d6416f4516f 232 Gene3D G3DSA:3.40.50.300 1 222 1.0E-58 T 29-03-2018 HVS_RS08280 72447f870a5530c8e93a4d6416f4516f 232 Pfam PF00005 ABC transporter 22 165 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS05360 9826a7ff0f0e95c495a28892a3ee53c8 208 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 204 1.1E-46 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA HVS_RS03060 5e980f6f43e4029eefb319b500ef7259 38 Pfam PF13673 Acetyltransferase (GNAT) domain 3 34 1.9E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS03060 5e980f6f43e4029eefb319b500ef7259 38 SUPERFAMILY SSF55729 3 35 1.74E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS03060 5e980f6f43e4029eefb319b500ef7259 38 Gene3D G3DSA:3.40.630.30 1 38 5.7E-7 T 29-03-2018 HVS_RS13690 5e980f6f43e4029eefb319b500ef7259 38 Pfam PF13673 Acetyltransferase (GNAT) domain 3 34 1.9E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS13690 5e980f6f43e4029eefb319b500ef7259 38 SUPERFAMILY SSF55729 3 35 1.74E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS13690 5e980f6f43e4029eefb319b500ef7259 38 Gene3D G3DSA:3.40.630.30 1 38 5.7E-7 T 29-03-2018 HVS_RS02460 01fb5a6df6c263f726617d7b063c0123 273 Gene3D G3DSA:1.20.1540.10 16 192 2.2E-17 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS02460 01fb5a6df6c263f726617d7b063c0123 273 Pfam PF01694 Rhomboid family 57 162 4.1E-7 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS02460 01fb5a6df6c263f726617d7b063c0123 273 SUPERFAMILY SSF144091 19 170 3.27E-16 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS05680 187927dd9f6893c5193b6ec3200305b6 195 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 4.5E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05680 187927dd9f6893c5193b6ec3200305b6 195 Gene3D G3DSA:3.30.457.10 61 122 1.4E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05680 187927dd9f6893c5193b6ec3200305b6 195 Gene3D G3DSA:3.30.457.10 5 60 1.3E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05680 187927dd9f6893c5193b6ec3200305b6 195 Gene3D G3DSA:3.30.457.10 123 180 1.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05680 187927dd9f6893c5193b6ec3200305b6 195 SUPERFAMILY SSF55383 51 134 4.58E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS11830 c6f99c89de59953e7928c69e4700be9a 192 Gene3D G3DSA:3.40.470.10 4 192 1.6E-35 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11830 c6f99c89de59953e7928c69e4700be9a 192 SUPERFAMILY SSF52141 21 191 3.92E-39 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11830 c6f99c89de59953e7928c69e4700be9a 192 SMART SM00986 25 185 3.0E-21 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS11830 c6f99c89de59953e7928c69e4700be9a 192 SMART SM00987 25 185 3.0E-21 T 29-03-2018 HVS_RS11830 c6f99c89de59953e7928c69e4700be9a 192 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 22 191 3.2E-39 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 HVS_RS11830 c6f99c89de59953e7928c69e4700be9a 192 Pfam PF03167 Uracil DNA glycosylase superfamily 26 184 3.9E-33 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 HVS_RS10250 3d0c38eb6a4b0bdd15d383fb4313765a 254 SUPERFAMILY SSF69989 39 134 6.15E-5 T 29-03-2018 HVS_RS10250 3d0c38eb6a4b0bdd15d383fb4313765a 254 Pfam PF02108 Flagellar assembly protein FliH 109 242 3.7E-22 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE HVS_RS10250 3d0c38eb6a4b0bdd15d383fb4313765a 254 Gene3D G3DSA:1.20.5.620 101 151 0.17 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS10250 3d0c38eb6a4b0bdd15d383fb4313765a 254 Gene3D G3DSA:1.20.5.620 48 100 0.011 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS14565 2c7b3bfd8f255019e206429e7f9b1e5e 140 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 4 130 2.8E-35 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HVS_RS14565 2c7b3bfd8f255019e206429e7f9b1e5e 140 SUPERFAMILY SSF47188 1 130 2.75E-29 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HVS_RS14565 2c7b3bfd8f255019e206429e7f9b1e5e 140 Gene3D G3DSA:1.20.120.50 1 135 2.2E-33 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 HVS_RS14565 2c7b3bfd8f255019e206429e7f9b1e5e 140 Pfam PF01814 Hemerythrin HHE cation binding domain 13 121 1.4E-9 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 Pfam PF06971 Putative DNA-binding protein N-terminus 6 54 5.5E-21 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 SMART SM00881 80 181 1.1E-18 T 29-03-2018 IPR003781 CoA-binding GO:0048037 HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 210 34.631 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 Pfam PF02629 CoA binding domain 84 179 3.7E-20 T 29-03-2018 IPR003781 CoA-binding GO:0048037 HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 Gene3D G3DSA:1.10.10.10 5 71 1.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 SUPERFAMILY SSF51735 82 206 2.8E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 SUPERFAMILY SSF46785 10 80 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS12680 68cac7482eaba2d0fb0ce3800b879156 220 Gene3D G3DSA:3.40.50.720 72 188 2.4E-23 T 29-03-2018 HVS_RS12110 899b6d1677e6c96b1b18fe8d65a1b227 241 Pfam PF02811 PHP domain 6 82 1.8E-7 T 29-03-2018 IPR004013 PHP domain GO:0003824 HVS_RS12110 899b6d1677e6c96b1b18fe8d65a1b227 241 SMART SM00481 5 79 2.7E-12 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HVS_RS12110 899b6d1677e6c96b1b18fe8d65a1b227 241 Gene3D G3DSA:3.20.20.140 6 231 2.4E-36 T 29-03-2018 HVS_RS12110 899b6d1677e6c96b1b18fe8d65a1b227 241 SUPERFAMILY SSF89550 4 237 1.15E-60 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 Pfam PF00462 Glutaredoxin 3 62 4.7E-20 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 PRINTS PR00160 Glutaredoxin signature 45 58 8.4E-5 T 29-03-2018 IPR014025 Glutaredoxin subgroup HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 PRINTS PR00160 Glutaredoxin signature 3 21 8.4E-5 T 29-03-2018 IPR014025 Glutaredoxin subgroup HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 SUPERFAMILY SSF52833 1 67 1.57E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 Gene3D G3DSA:3.40.30.10 1 72 3.2E-21 T 29-03-2018 HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 ProSitePatterns PS00195 Glutaredoxin active site. 5 21 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 HVS_RS01835 a373d32573c9a8e24dbc5e46f897b1d7 76 TIGRFAM TIGR02196 GlrX_YruB: glutaredoxin-like protein, YruB-family 3 74 4.6E-30 T 29-03-2018 IPR011911 Glutaredoxin-like protein, YruB HVS_RS00720 d9ca2231e79c48668b011ae1d55e1436 75 PIRSF PIRSF037031 1 75 1.6E-32 T 29-03-2018 IPR005243 Redox-active disulphide protein 2 HVS_RS00720 d9ca2231e79c48668b011ae1d55e1436 75 Pfam PF13192 Thioredoxin domain 1 74 6.1E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS00720 d9ca2231e79c48668b011ae1d55e1436 75 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 74 4.6E-28 T 29-03-2018 IPR005243 Redox-active disulphide protein 2 HVS_RS00720 d9ca2231e79c48668b011ae1d55e1436 75 SUPERFAMILY SSF52833 1 75 1.3E-19 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS00720 d9ca2231e79c48668b011ae1d55e1436 75 Gene3D G3DSA:3.40.30.10 1 75 1.7E-11 T 29-03-2018 HVS_RS10220 eafdd9f08dd7fe60650da98db944ea84 129 Pfam PF12611 Putative flagellar 106 128 5.2E-12 T 29-03-2018 IPR013367 Flagellar, putative HVS_RS10220 eafdd9f08dd7fe60650da98db944ea84 129 TIGRFAM TIGR02530 flg_new: flagellar operon protein 33 129 1.0E-33 T 29-03-2018 IPR013367 Flagellar, putative HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Gene3D G3DSA:2.10.270.10 224 397 5.6E-4 T 29-03-2018 HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Gene3D G3DSA:2.10.270.10 20 223 1.5E-4 T 29-03-2018 HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 235 268 1.6E-9 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 58 91 3.7E-9 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 129 163 2.1E-7 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 269 301 1.1E-6 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 306 343 3.9E-5 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 202 234 1.9E-12 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 Pfam PF14903 WG containing repeat 163 194 1.0E-8 T 29-03-2018 IPR032774 WG containing repeat HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 SUPERFAMILY SSF69360 231 285 3.14E-15 T 29-03-2018 HVS_RS07370 3f57b3038416b7c0f58a751dffd0b7e0 803 SUPERFAMILY SSF69360 126 178 3.14E-15 T 29-03-2018 HVS_RS10875 40ee00a10bd1303834ff9106f66a1037 187 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 7 187 1.3E-49 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 HVS_RS10875 40ee00a10bd1303834ff9106f66a1037 187 Pfam PF03602 Conserved hypothetical protein 95 7 187 1.2E-56 T 29-03-2018 HVS_RS10875 40ee00a10bd1303834ff9106f66a1037 187 Gene3D G3DSA:3.40.50.150 5 181 3.6E-30 T 29-03-2018 HVS_RS10875 40ee00a10bd1303834ff9106f66a1037 187 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 123 129 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS10875 40ee00a10bd1303834ff9106f66a1037 187 PIRSF PIRSF004553 6 187 2.3E-52 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 HVS_RS10875 40ee00a10bd1303834ff9106f66a1037 187 SUPERFAMILY SSF53335 7 187 3.84E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS07775 2c015caee7df06296ab3cdfc1a6c6676 250 SMART SM00382 33 212 4.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS07775 2c015caee7df06296ab3cdfc1a6c6676 250 Gene3D G3DSA:3.40.50.300 1 244 7.6E-54 T 29-03-2018 HVS_RS07775 2c015caee7df06296ab3cdfc1a6c6676 250 SUPERFAMILY SSF52540 5 240 5.81E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07775 2c015caee7df06296ab3cdfc1a6c6676 250 Pfam PF00005 ABC transporter 24 163 2.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS07775 2c015caee7df06296ab3cdfc1a6c6676 250 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS11170 34f177483118ba8da5131d6382233f1f 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.934 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HVS_RS11170 34f177483118ba8da5131d6382233f1f 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 1.3E-58 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HVS_RS11170 34f177483118ba8da5131d6382233f1f 149 Gene3D G3DSA:3.50.80.10 1 145 2.0E-59 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain HVS_RS11170 34f177483118ba8da5131d6382233f1f 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 7.2E-58 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 HVS_RS11170 34f177483118ba8da5131d6382233f1f 149 SUPERFAMILY SSF69500 1 145 7.72E-59 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain HVS_RS12745 a910218207b67910c98b4e5db9745a04 370 Pfam PF01882 Protein of unknown function DUF58 180 262 1.3E-16 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 SMART SM00327 346 518 6.7E-31 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00092 von Willebrand factor type A domain 348 509 1.9E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 SUPERFAMILY SSF53300 343 516 1.06E-37 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00395 S-layer homology domain 32 73 3.6E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00395 S-layer homology domain 156 196 6.2E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00395 S-layer homology domain 91 134 8.7E-14 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06030 98178a3007e11d0ef6f5ad41f96a1e5f 804 Gene3D G3DSA:3.40.50.410 344 537 5.6E-38 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 SMART SM00327 346 518 6.7E-31 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00092 von Willebrand factor type A domain 348 509 1.9E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 SUPERFAMILY SSF53300 343 516 1.06E-37 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00395 S-layer homology domain 32 73 3.6E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00395 S-layer homology domain 156 196 6.2E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 Pfam PF00395 S-layer homology domain 91 134 8.7E-14 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS14795 98178a3007e11d0ef6f5ad41f96a1e5f 804 Gene3D G3DSA:3.40.50.410 344 537 5.6E-38 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09480 5df3226cc4a0fc45405a21756f15b280 434 Pfam PF01882 Protein of unknown function DUF58 191 276 1.2E-22 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS09480 5df3226cc4a0fc45405a21756f15b280 434 SUPERFAMILY SSF53300 227 361 3.71E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS09480 5df3226cc4a0fc45405a21756f15b280 434 Gene3D G3DSA:3.40.50.410 203 366 2.2E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS07385 9d443f1ebef56eedcc6cb2094735c731 309 SUPERFAMILY SSF88713 110 309 8.9E-64 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HVS_RS07385 9d443f1ebef56eedcc6cb2094735c731 309 Gene3D G3DSA:3.20.20.370 97 309 1.3E-58 T 29-03-2018 HVS_RS07385 9d443f1ebef56eedcc6cb2094735c731 309 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 89 309 7.1E-97 T 29-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA HVS_RS07385 9d443f1ebef56eedcc6cb2094735c731 309 Pfam PF01522 Polysaccharide deacetylase 120 240 5.0E-34 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 Pfam PF01471 Putative peptidoglycan binding domain 190 246 1.1E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 Pfam PF01471 Putative peptidoglycan binding domain 286 343 6.3E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 SUPERFAMILY SSF47090 178 248 4.71E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 Gene3D G3DSA:1.20.1170.10 2 187 3.6E-6 T 29-03-2018 HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 SUPERFAMILY SSF47090 283 344 3.4E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 Gene3D G3DSA:1.10.101.10 276 349 1.7E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03520 877a6a7e873d31ed3efbd3a78b6c2ff1 601 Gene3D G3DSA:1.10.101.10 188 255 7.0E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS07295 80ec94aa5ab2b3edca8d1de7ba1f72ca 87 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 2.0E-34 T 29-03-2018 IPR007347 Sporulation stage V, protein S HVS_RS07295 80ec94aa5ab2b3edca8d1de7ba1f72ca 87 Pfam PF04232 Stage V sporulation protein S (SpoVS) 3 84 1.6E-37 T 29-03-2018 IPR007347 Sporulation stage V, protein S HVS_RS03235 a62f84eeeda06c773a2937b83bcdc76a 149 SMART SM00530 8 64 2.0E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS03235 a62f84eeeda06c773a2937b83bcdc76a 149 SUPERFAMILY SSF47413 3 70 3.22E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS03235 a62f84eeeda06c773a2937b83bcdc76a 149 Pfam PF01381 Helix-turn-helix 9 62 6.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS03235 a62f84eeeda06c773a2937b83bcdc76a 149 Gene3D G3DSA:1.10.260.40 5 148 5.9E-20 T 29-03-2018 HVS_RS13360 42973a14e95b1a3351dab142f234c7ae 241 Gene3D G3DSA:3.40.50.300 25 221 3.0E-13 T 29-03-2018 HVS_RS13360 42973a14e95b1a3351dab142f234c7ae 241 PIRSF PIRSF003073 3 241 1.1E-66 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS13360 42973a14e95b1a3351dab142f234c7ae 241 Pfam PF01695 IstB-like ATP binding protein 52 224 3.3E-54 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS13360 42973a14e95b1a3351dab142f234c7ae 241 SUPERFAMILY SSF52540 68 226 2.48E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00545 23ff007bde98767deabd051bc4e2515c 353 SUPERFAMILY SSF54534 223 305 2.22E-6 T 29-03-2018 HVS_RS00545 23ff007bde98767deabd051bc4e2515c 353 SUPERFAMILY SSF109998 30 188 2.35E-8 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS00545 23ff007bde98767deabd051bc4e2515c 353 Pfam PF13616 PPIC-type PPIASE domain 223 304 9.5E-7 T 29-03-2018 HVS_RS00545 23ff007bde98767deabd051bc4e2515c 353 Gene3D G3DSA:3.10.50.40 209 340 1.3E-11 T 29-03-2018 HVS_RS06190 ddadd9c1d1857c43a8fc019285282765 88 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 16 86 8.8E-21 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D HVS_RS08705 955a43e26bea6183849698bca2623e10 262 Gene3D G3DSA:3.20.20.150 1 259 1.1E-29 T 29-03-2018 HVS_RS08705 955a43e26bea6183849698bca2623e10 262 SUPERFAMILY SSF51658 2 257 2.62E-56 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS08705 955a43e26bea6183849698bca2623e10 262 SMART SM00518 3 255 7.9E-47 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 HVS_RS08705 955a43e26bea6183849698bca2623e10 262 Pfam PF01261 Xylose isomerase-like TIM barrel 3 209 4.5E-16 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain HVS_RS00225 85a0a8018af4b323e87438356a89eb13 463 Pfam PF14620 YpeB sporulation 26 387 2.0E-130 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 HVS_RS00225 85a0a8018af4b323e87438356a89eb13 463 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 22 452 6.9E-142 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 HVS_RS06980 c94985b398bc1feaf2a63ae2e70c380c 82 SUPERFAMILY SSF55021 1 80 6.66E-19 T 29-03-2018 HVS_RS06980 c94985b398bc1feaf2a63ae2e70c380c 82 Gene3D G3DSA:3.30.70.1150 3 80 8.6E-25 T 29-03-2018 HVS_RS12720 70bf66f89092cc0df7df78cf4174b57e 276 SUPERFAMILY SSF53167 4 183 1.47E-18 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HVS_RS12720 70bf66f89092cc0df7df78cf4174b57e 276 Gene3D G3DSA:3.40.50.1580 1 117 5.6E-9 T 29-03-2018 HVS_RS12720 70bf66f89092cc0df7df78cf4174b57e 276 Gene3D G3DSA:3.40.50.1580 118 185 0.0023 T 29-03-2018 HVS_RS01135 5fe32a562ac1e3760385a1de354dd48b 154 Gene3D G3DSA:3.40.140.10 1 154 1.6E-41 T 29-03-2018 HVS_RS01135 5fe32a562ac1e3760385a1de354dd48b 154 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 6.5E-26 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HVS_RS01135 5fe32a562ac1e3760385a1de354dd48b 154 SUPERFAMILY SSF53927 2 122 2.83E-44 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 HVS_RS01135 5fe32a562ac1e3760385a1de354dd48b 154 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 88 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HVS_RS15605 833daf34e5047687bceb34b8596075a7 110 Gene3D G3DSA:3.30.70.120 1 107 8.5E-12 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HVS_RS15605 833daf34e5047687bceb34b8596075a7 110 SUPERFAMILY SSF54913 5 107 2.95E-8 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta HVS_RS14115 885f4a4139921eb5ba9765ec814a2132 335 SUPERFAMILY SSF48452 34 164 1.93E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14115 885f4a4139921eb5ba9765ec814a2132 335 Gene3D G3DSA:1.20.58.280 113 200 4.6E-4 T 29-03-2018 HVS_RS14115 885f4a4139921eb5ba9765ec814a2132 335 Gene3D G3DSA:1.25.40.10 89 112 0.03 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS14115 885f4a4139921eb5ba9765ec814a2132 335 Gene3D G3DSA:1.25.40.10 33 88 3.6E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.5E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.5E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.5E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.5E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.5E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.5E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 246 1.8E-104 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 SUPERFAMILY SSF51735 4 247 5.63E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 1.1E-4 T 29-03-2018 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 Gene3D G3DSA:3.40.50.720 1 40 2.6E-8 T 29-03-2018 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 Gene3D G3DSA:3.40.50.720 41 247 3.1E-73 T 29-03-2018 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 245 2.5E-73 T 29-03-2018 HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08820 49b312b6ee0d2210c86fcfd83a712037 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR HVS_RS08630 0fbaab3a28076501326cbe032f182389 81 Pfam PF10031 Small integral membrane protein (DUF2273) 14 60 1.6E-15 T 29-03-2018 IPR018730 Protein of unknown function DUF2273 HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 SUPERFAMILY SSF55874 150 296 2.75E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 PRINTS PR00344 Bacterial sensor protein C-terminal signature 282 295 7.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 PRINTS PR00344 Bacterial sensor protein C-terminal signature 257 275 7.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 PRINTS PR00344 Bacterial sensor protein C-terminal signature 227 241 7.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 192 296 3.6E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 SMART SM00387 189 298 1.7E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS14940 0163017ed5e07adb48f31f14ecb0bea0 301 Gene3D G3DSA:3.30.565.10 147 301 1.2E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS05895 a83b5916bf797c66e40a62180e7d5fea 363 SUPERFAMILY SSF48576 8 362 6.24E-76 T 29-03-2018 IPR008949 Isoprenoid synthase domain HVS_RS05895 a83b5916bf797c66e40a62180e7d5fea 363 Pfam PF00348 Polyprenyl synthetase 34 313 1.7E-52 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 HVS_RS05895 a83b5916bf797c66e40a62180e7d5fea 363 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site HVS_RS05895 a83b5916bf797c66e40a62180e7d5fea 363 Gene3D G3DSA:1.10.600.10 1 363 3.2E-80 T 29-03-2018 IPR008949 Isoprenoid synthase domain HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.6E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.6E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.6E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.6E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.6E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 SUPERFAMILY SSF52096 10 193 3.36E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 Pfam PF00574 Clp protease 13 192 1.4E-87 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.9E-104 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.145 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 29-03-2018 IPR018215 ClpP, Ser active site HVS_RS12885 bbecb5a0d2a996b2512a4ee502f095da 194 Gene3D G3DSA:3.90.226.10 2 194 3.5E-45 T 29-03-2018 HVS_RS05270 41a228804b46d3df1b7b73ed19f344f9 208 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS05270 41a228804b46d3df1b7b73ed19f344f9 208 Pfam PF00005 ABC transporter 18 155 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS05270 41a228804b46d3df1b7b73ed19f344f9 208 Gene3D G3DSA:3.40.50.300 2 208 1.9E-53 T 29-03-2018 HVS_RS05270 41a228804b46d3df1b7b73ed19f344f9 208 SUPERFAMILY SSF52540 9 207 1.25E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05270 41a228804b46d3df1b7b73ed19f344f9 208 SMART SM00382 22 205 2.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS08295 6507ff26763bb8549b46151ed7c63db9 194 Pfam PF04229 GrpB protein 17 180 2.7E-41 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase HVS_RS08295 6507ff26763bb8549b46151ed7c63db9 194 SUPERFAMILY SSF81301 19 184 5.56E-43 T 29-03-2018 HVS_RS08295 6507ff26763bb8549b46151ed7c63db9 194 Gene3D G3DSA:3.30.460.10 14 188 1.1E-45 T 29-03-2018 HVS_RS15895 4bffb91232cc2a7b7853bd112885709f 67 Pfam PF14202 Transposon-encoded protein TnpW 10 42 2.0E-11 T 29-03-2018 IPR026990 Transposon-encoded protein TnpW HVS_RS01435 0ea7ac63b333e2f31bd21f0df7b29fca 213 SUPERFAMILY SSF53328 43 163 1.7E-19 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS01435 0ea7ac63b333e2f31bd21f0df7b29fca 213 Pfam PF00551 Formyl transferase 43 130 8.5E-10 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS01435 0ea7ac63b333e2f31bd21f0df7b29fca 213 SUPERFAMILY SSF50486 166 205 5.34E-6 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 HVS_RS01435 0ea7ac63b333e2f31bd21f0df7b29fca 213 Gene3D G3DSA:3.40.50.170 18 176 8.4E-21 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HVS_RS12325 b2a472f7a39917f5b3e0f46938dd684a 304 SUPERFAMILY SSF160964 15 50 4.05E-6 T 29-03-2018 HVS_RS12325 b2a472f7a39917f5b3e0f46938dd684a 304 Gene3D G3DSA:1.10.3720.10 15 300 1.7E-53 T 29-03-2018 HVS_RS12325 b2a472f7a39917f5b3e0f46938dd684a 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 293 7.4E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS12325 b2a472f7a39917f5b3e0f46938dd684a 304 SUPERFAMILY SSF161098 57 293 7.85E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS05010 9eeb3f80b772ba37a52eb1468e03a521 440 Pfam PF03787 RAMP superfamily 20 183 9.7E-11 T 29-03-2018 IPR005537 CRISPR type III-associated RAMP protein HVS_RS05010 9eeb3f80b772ba37a52eb1468e03a521 440 Pfam PF03787 RAMP superfamily 233 402 2.9E-13 T 29-03-2018 IPR005537 CRISPR type III-associated RAMP protein HVS_RS13965 639e686d59657b40126cf189b10f0b0b 305 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 275 294 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS13965 639e686d59657b40126cf189b10f0b0b 305 SUPERFAMILY SSF63446 237 304 4.91E-17 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS13965 639e686d59657b40126cf189b10f0b0b 305 Gene3D G3DSA:1.10.1330.10 234 305 8.5E-5 T 29-03-2018 HVS_RS13965 639e686d59657b40126cf189b10f0b0b 305 Pfam PF00404 Dockerin type I repeat 241 260 2.3E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS13965 639e686d59657b40126cf189b10f0b0b 305 ProSitePatterns PS00018 EF-hand calcium-binding domain. 275 287 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS13965 639e686d59657b40126cf189b10f0b0b 305 Gene3D G3DSA:2.160.20.10 35 145 0.093 T 29-03-2018 IPR012334 Pectin lyase fold HVS_RS07590 7309854834b90b0f697ed523d083c903 512 Pfam PF00425 chorismate binding enzyme 230 483 4.2E-95 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal HVS_RS07590 7309854834b90b0f697ed523d083c903 512 SUPERFAMILY SSF56322 16 492 1.09E-158 T 29-03-2018 IPR005801 ADC synthase GO:0009058 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 Gene3D G3DSA:3.60.120.10 15 493 3.2E-165 T 29-03-2018 IPR005801 ADC synthase GO:0009058 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 Pfam PF04715 Anthranilate synthase component I, N terminal region 28 168 8.1E-41 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 491 7.0E-176 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 PRINTS PR00095 Anthranilate synthase component I signature 440 454 1.7E-21 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 PRINTS PR00095 Anthranilate synthase component I signature 331 344 1.7E-21 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 PRINTS PR00095 Anthranilate synthase component I signature 425 439 1.7E-21 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS07590 7309854834b90b0f697ed523d083c903 512 PRINTS PR00095 Anthranilate synthase component I signature 345 358 1.7E-21 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 HVS_RS08345 a1f84d8bcfd78eebd027c5bc329e9d3c 127 SUPERFAMILY SSF56784 3 82 1.29E-7 T 29-03-2018 IPR023214 HAD-like domain HVS_RS08345 a1f84d8bcfd78eebd027c5bc329e9d3c 127 Gene3D G3DSA:3.40.50.1000 2 121 5.4E-8 T 29-03-2018 IPR023214 HAD-like domain HVS_RS12605 a63de17ada96000fe8347b84879ef887 418 SUPERFAMILY SSF53448 50 331 5.63E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS12605 a63de17ada96000fe8347b84879ef887 418 Gene3D G3DSA:3.90.550.10 51 291 9.2E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS12605 a63de17ada96000fe8347b84879ef887 418 Pfam PF13641 Glycosyltransferase like family 2 51 275 1.1E-30 T 29-03-2018 HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 TIGRFAM TIGR01441 GPR: GPR endopeptidase 4 259 6.9E-111 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 5 306 6.0E-84 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 Hamap MF_00626 Germination protease [gpr]. 1 328 163.732 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 Gene3D G3DSA:3.40.50.1450 2 324 1.0E-124 T 29-03-2018 IPR023430 Peptidase HybD-like domain HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 SUPERFAMILY SSF53163 4 327 1.18E-121 T 29-03-2018 IPR023430 Peptidase HybD-like domain HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 Pfam PF03418 Germination protease 11 265 5.2E-96 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 PIRSF PIRSF019549 2 260 3.6E-116 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HVS_RS07195 80e0d74997fe4150a45879d53767d520 328 PIRSF PIRSF019549 252 328 1.9E-26 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 HVS_RS01460 6a57438c4bc175aed399ab77def9a9e8 383 PIRSF PIRSF000390 3 383 5.4E-131 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HVS_RS01460 6a57438c4bc175aed399ab77def9a9e8 383 Gene3D G3DSA:3.90.1150.10 243 383 1.6E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS01460 6a57438c4bc175aed399ab77def9a9e8 383 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 378 3.7E-136 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase HVS_RS01460 6a57438c4bc175aed399ab77def9a9e8 383 Gene3D G3DSA:3.40.640.10 13 242 1.6E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS01460 6a57438c4bc175aed399ab77def9a9e8 383 SUPERFAMILY SSF53383 6 381 5.3E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS01460 6a57438c4bc175aed399ab77def9a9e8 383 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 6 381 1.1E-159 T 29-03-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase HVS_RS07990 ae60076232c23efc3e6922d9e3c8de12 218 Gene3D G3DSA:2.40.10.220 94 201 2.3E-15 T 29-03-2018 HVS_RS07990 ae60076232c23efc3e6922d9e3c8de12 218 SUPERFAMILY SSF141371 87 200 3.14E-8 T 29-03-2018 HVS_RS07990 ae60076232c23efc3e6922d9e3c8de12 218 Pfam PF07238 PilZ domain 91 185 3.8E-12 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 228 242 3.0E-20 T 29-03-2018 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 339 363 3.0E-20 T 29-03-2018 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 202 218 3.0E-20 T 29-03-2018 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 301 313 3.0E-20 T 29-03-2018 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 SUPERFAMILY SSF53335 12 50 1.98E-130 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 SUPERFAMILY SSF53335 87 520 1.98E-130 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 Gene3D G3DSA:3.40.50.150 200 480 1.1E-68 T 29-03-2018 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 Pfam PF02384 N-6 DNA Methylase 179 486 9.4E-114 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 508 4.8E-231 T 29-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS15875 42e15f4dd282305be6ae4cd5f6a22a56 522 Pfam PF12161 HsdM N-terminal domain 13 165 1.3E-21 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HVS_RS09525 9938484b4d274ff41a1f64c1182836b7 209 PIRSF PIRSF038973 2 209 2.8E-54 T 29-03-2018 IPR014196 Stage II sporulation protein M HVS_RS09525 9938484b4d274ff41a1f64c1182836b7 209 Pfam PF01944 Stage II sporulation protein M 24 200 3.3E-20 T 29-03-2018 IPR002798 Stage II sporulation protein M-like HVS_RS09525 9938484b4d274ff41a1f64c1182836b7 209 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 8 206 4.0E-51 T 29-03-2018 IPR014196 Stage II sporulation protein M HVS_RS03690 d25c0c0d5039f3f86d2b4e4bef3c9437 265 Pfam PF13401 AAA domain 42 170 1.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS03690 d25c0c0d5039f3f86d2b4e4bef3c9437 265 Gene3D G3DSA:3.40.50.300 13 208 4.9E-8 T 29-03-2018 HVS_RS03690 d25c0c0d5039f3f86d2b4e4bef3c9437 265 SUPERFAMILY SSF52540 15 250 5.81E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12015 b490330a35816a8326329b813ec7e376 331 Gene3D G3DSA:3.40.50.1820 93 326 1.2E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS12015 b490330a35816a8326329b813ec7e376 331 Pfam PF00561 alpha/beta hydrolase fold 97 226 1.6E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 HVS_RS12015 b490330a35816a8326329b813ec7e376 331 SUPERFAMILY SSF53474 264 326 1.25E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS12015 b490330a35816a8326329b813ec7e376 331 SUPERFAMILY SSF53474 96 223 1.25E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS12425 5e9f5e97dd9b70e06e64705a98d631be 248 Pfam PF02535 ZIP Zinc transporter 99 245 1.3E-24 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 165 8.4E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 Gene3D G3DSA:1.10.150.240 15 71 1.1E-13 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 182 2.5E-31 T 29-03-2018 IPR023214 HAD-like domain HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 Gene3D G3DSA:3.40.50.1000 72 216 1.0E-25 T 29-03-2018 IPR023214 HAD-like domain HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 SUPERFAMILY SSF56784 1 212 6.67E-47 T 29-03-2018 IPR023214 HAD-like domain HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 181 6.2E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 3.8E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 142 3.8E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HVS_RS02485 1e75c73739d1ffeb14125c4720d78f65 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 164 3.8E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HVS_RS15975 f9a206bedeb6828afa96e5725307cc6e 72 SUPERFAMILY SSF140500 2 54 3.27E-7 T 29-03-2018 HVS_RS15975 f9a206bedeb6828afa96e5725307cc6e 72 Pfam PF09388 Spo0E like sporulation regulatory protein 12 48 6.3E-7 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 HVS_RS06355 fc5694e535bb7a0ed323405f6b674c7c 185 SUPERFAMILY SSF55194 5 184 1.44E-69 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 HVS_RS06355 fc5694e535bb7a0ed323405f6b674c7c 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 6.0E-70 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 HVS_RS06355 fc5694e535bb7a0ed323405f6b674c7c 185 Pfam PF01765 Ribosome recycling factor 20 183 3.7E-63 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 HVS_RS06355 fc5694e535bb7a0ed323405f6b674c7c 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.678 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 HVS_RS06355 fc5694e535bb7a0ed323405f6b674c7c 185 Gene3D G3DSA:1.10.132.20 73 184 6.5E-38 T 29-03-2018 HVS_RS06355 fc5694e535bb7a0ed323405f6b674c7c 185 Gene3D G3DSA:1.10.132.20 3 72 2.8E-10 T 29-03-2018 HVS_RS07615 2d2517145121e5668ae5813dacd3b0c1 265 SUPERFAMILY SSF69572 5 263 1.02E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HVS_RS07615 2d2517145121e5668ae5813dacd3b0c1 265 Gene3D G3DSA:3.40.50.720 3 265 4.4E-49 T 29-03-2018 HVS_RS07615 2d2517145121e5668ae5813dacd3b0c1 265 Pfam PF00899 ThiF family 8 260 4.0E-39 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 HVS_RS03885 ad9c8f9b15561a9ff34db1b47dcc4907 175 Pfam PF04986 Putative transposase 3 64 7.4E-18 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS04505 b982020d06c14c77ea746f46f8aa066d 482 Pfam PF14319 Transposase zinc-binding domain 32 140 1.1E-27 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS04505 b982020d06c14c77ea746f46f8aa066d 482 Pfam PF04986 Putative transposase 167 336 2.1E-24 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS12835 256a08c550689904f7ad0764633ddd58 275 Pfam PF02517 CAAX protease self-immunity 146 234 4.3E-21 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 HVS_RS10930 4117702dffa4821b7c20e708cc310c61 127 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 10 91 1.0E-11 T 29-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HVS_RS15185 6da949deeca647eb110e731b27c67da9 104 Pfam PF01740 STAS domain 16 101 6.1E-15 T 29-03-2018 IPR002645 STAS domain HVS_RS15185 6da949deeca647eb110e731b27c67da9 104 Gene3D G3DSA:3.30.750.24 5 104 1.7E-17 T 29-03-2018 IPR002645 STAS domain HVS_RS15185 6da949deeca647eb110e731b27c67da9 104 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 103 6.0E-24 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 HVS_RS15185 6da949deeca647eb110e731b27c67da9 104 SUPERFAMILY SSF52091 6 103 2.35E-24 T 29-03-2018 IPR002645 STAS domain HVS_RS01275 6cd7d8a2e704d68642548833fc5d0ec6 198 Gene3D G3DSA:1.20.5.620 9 51 3.4E-8 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS01275 6cd7d8a2e704d68642548833fc5d0ec6 198 Gene3D G3DSA:1.20.5.620 52 84 3.3E-4 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS01275 6cd7d8a2e704d68642548833fc5d0ec6 198 Pfam PF01991 ATP synthase (E/31 kDa) subunit 11 198 5.1E-22 T 29-03-2018 IPR002842 ATPase, V1/A1 complex, subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01275 6cd7d8a2e704d68642548833fc5d0ec6 198 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 198 12.263 T 29-03-2018 IPR002842 ATPase, V1/A1 complex, subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01275 6cd7d8a2e704d68642548833fc5d0ec6 198 SUPERFAMILY SSF81573 10 62 3.86E-5 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS01275 6cd7d8a2e704d68642548833fc5d0ec6 198 SUPERFAMILY SSF160527 81 198 1.7E-17 T 29-03-2018 HVS_RS06180 081bc0b59de02a9218d52a40c78a6b22 385 Pfam PF00395 S-layer homology domain 90 137 3.7E-5 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06180 081bc0b59de02a9218d52a40c78a6b22 385 Pfam PF00395 S-layer homology domain 33 73 4.2E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06180 081bc0b59de02a9218d52a40c78a6b22 385 Pfam PF00395 S-layer homology domain 162 197 0.0016 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01405 a171bf7855022e1e4f4379be18fa42d6 73 TIGRFAM TIGR00202 csrA: carbon storage regulator 2 67 2.1E-28 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HVS_RS01405 a171bf7855022e1e4f4379be18fa42d6 73 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 4.0E-17 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HVS_RS01405 a171bf7855022e1e4f4379be18fa42d6 73 Hamap MF_00167 Carbon storage regulator [csrA]. 1 71 21.292 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HVS_RS01405 a171bf7855022e1e4f4379be18fa42d6 73 Pfam PF02599 Global regulator protein family 2 52 3.1E-26 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HVS_RS01405 a171bf7855022e1e4f4379be18fa42d6 73 SUPERFAMILY SSF117130 2 55 1.57E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 HVS_RS04245 268cff5aab284c2ce97b4d5bdcb8e7e0 62 Pfam PF05717 IS66 Orf2 like protein 9 61 3.2E-18 T 29-03-2018 IPR008878 Transposase IS66, Orf2 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 Gene3D G3DSA:3.30.420.10 1 158 2.9E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 148 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 156 4.4E-49 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 6.5E-56 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 4.5E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 4.5E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 4.5E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 4.5E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 4.5E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 154 46.488 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 HVS_RS11520 1ca6ad5c27243f2a420e18381a59173a 162 SUPERFAMILY SSF53098 1 158 3.64E-54 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 139 4.2E-51 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 Gene3D G3DSA:2.10.260.10 74 123 3.5E-8 T 29-03-2018 HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 Gene3D G3DSA:2.10.260.10 3 64 1.2E-6 T 29-03-2018 HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 54.932 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 SUPERFAMILY SSF89447 2 127 3.51E-51 T 29-03-2018 HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 1.7E-19 T 29-03-2018 IPR020603 MraZ domain HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 126 3.3E-23 T 29-03-2018 IPR020603 MraZ domain HVS_RS10470 4477ab896fa1d557d55a7d9dffce4a75 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 2.0E-58 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 HVS_RS09625 2ba14545306f04541efe8a0a8b114686 155 Pfam PF05103 DivIVA protein 3 132 4.7E-40 T 29-03-2018 IPR007793 DivIVA family HVS_RS09625 2ba14545306f04541efe8a0a8b114686 155 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 4 37 1.6E-8 T 29-03-2018 IPR019933 DivIVA domain HVS_RS07375 6f608eb12b945783c43d21bf35609620 617 Pfam PF01609 Transposase DDE domain 355 581 1.2E-8 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HVS_RS03860 19b79035b09690a10fe4584bf3cecec9 278 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 143 167 3.5E-4 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS03860 19b79035b09690a10fe4584bf3cecec9 278 Pfam PF07591 Pretoxin HINT domain 38 167 2.3E-30 T 29-03-2018 HVS_RS03860 19b79035b09690a10fe4584bf3cecec9 278 Gene3D G3DSA:2.170.16.10 18 166 5.1E-39 T 29-03-2018 HVS_RS03860 19b79035b09690a10fe4584bf3cecec9 278 SUPERFAMILY SSF51294 32 165 5.49E-27 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03860 19b79035b09690a10fe4584bf3cecec9 278 SMART SM00306 30 124 8.7E-12 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS10260 ad1af23af5b48a5c271969d9681ddea2 519 Pfam PF01514 Secretory protein of YscJ/FliF family 33 219 3.5E-45 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF HVS_RS10260 ad1af23af5b48a5c271969d9681ddea2 519 PRINTS PR01009 Flagellar M-ring protein signature 195 213 7.1E-6 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HVS_RS10260 ad1af23af5b48a5c271969d9681ddea2 519 PRINTS PR01009 Flagellar M-ring protein signature 152 166 7.1E-6 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HVS_RS10260 ad1af23af5b48a5c271969d9681ddea2 519 Pfam PF08345 Flagellar M-ring protein C-terminal 265 405 2.7E-8 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal HVS_RS10260 ad1af23af5b48a5c271969d9681ddea2 519 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 5 341 1.4E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 HVS_RS04310 ac52246a987f3f30da2be99932a7487b 178 SUPERFAMILY SSF54001 105 167 8.34E-12 T 29-03-2018 HVS_RS04310 ac52246a987f3f30da2be99932a7487b 178 Pfam PF01841 Transglutaminase-like superfamily 95 173 1.1E-13 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS00570 a5ed25633054ac3ddd6c1eea4b314923 97 Pfam PF07873 YabP family 14 78 1.8E-21 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC HVS_RS00570 a5ed25633054ac3ddd6c1eea4b314923 97 PIRSF PIRSF011576 2 97 3.2E-20 T 29-03-2018 IPR012504 Sporulation protein YabP HVS_RS00570 a5ed25633054ac3ddd6c1eea4b314923 97 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 12 88 3.0E-15 T 29-03-2018 IPR012504 Sporulation protein YabP HVS_RS00570 a5ed25633054ac3ddd6c1eea4b314923 97 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 14 97 3.7E-28 T 29-03-2018 IPR012504 Sporulation protein YabP HVS_RS05055 b4135b107a31be924a579535aaa35998 117 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 4 117 1.0E-49 T 29-03-2018 IPR014204 Sporulation stage V, protein AE HVS_RS05055 b4135b107a31be924a579535aaa35998 117 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 4 112 3.2E-39 T 29-03-2018 IPR005562 SpoVA HVS_RS15455 2e47ed56635b80cfa3062637f0e60fda 167 Gene3D G3DSA:3.90.350.10 2 151 6.9E-10 T 29-03-2018 IPR014736 Transposase, Tn5-like, core HVS_RS15455 2e47ed56635b80cfa3062637f0e60fda 167 Pfam PF01609 Transposase DDE domain 21 98 1.8E-5 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HVS_RS16090 62bb8ba726d7891bc3cb0ef5c718b15d 333 Gene3D G3DSA:1.10.10.60 265 325 1.1E-4 T 29-03-2018 HVS_RS16090 62bb8ba726d7891bc3cb0ef5c718b15d 333 Pfam PF04754 Putative transposase, YhgA-like 9 211 1.8E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS16090 62bb8ba726d7891bc3cb0ef5c718b15d 333 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 324 3.3E-16 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA HVS_RS11965 2660814b5d2301f389ac0dac1e90d7f5 329 Gene3D G3DSA:3.40.190.10 126 326 1.0E-31 T 29-03-2018 HVS_RS11965 2660814b5d2301f389ac0dac1e90d7f5 329 Pfam PF09084 NMT1/THI5 like 40 249 2.5E-19 T 29-03-2018 IPR015168 SsuA/THI5-like HVS_RS11965 2660814b5d2301f389ac0dac1e90d7f5 329 Gene3D G3DSA:3.40.190.10 23 123 3.9E-11 T 29-03-2018 HVS_RS11965 2660814b5d2301f389ac0dac1e90d7f5 329 SUPERFAMILY SSF53850 28 253 3.15E-33 T 29-03-2018 HVS_RS08460 9d25ee35eb53cad26eb3032051e91db7 97 SUPERFAMILY SSF56601 2 93 4.33E-23 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS08460 9d25ee35eb53cad26eb3032051e91db7 97 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 2 86 3.9E-21 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS08460 9d25ee35eb53cad26eb3032051e91db7 97 Gene3D G3DSA:3.40.710.10 1 96 8.5E-12 T 29-03-2018 HVS_RS00475 62af882c2e6c3f97f858585eea975c23 276 Gene3D G3DSA:3.40.50.1820 29 269 1.6E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS00475 62af882c2e6c3f97f858585eea975c23 276 SUPERFAMILY SSF53474 22 242 1.97E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS02740 a0ce4d412acead073f39d71919bfcb24 235 SMART SM00481 5 73 1.6E-6 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal HVS_RS02740 a0ce4d412acead073f39d71919bfcb24 235 Gene3D G3DSA:3.20.20.140 2 217 3.9E-22 T 29-03-2018 HVS_RS02740 a0ce4d412acead073f39d71919bfcb24 235 SUPERFAMILY SSF89550 4 83 9.29E-33 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS02740 a0ce4d412acead073f39d71919bfcb24 235 SUPERFAMILY SSF89550 128 233 9.29E-33 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 HVS_RS02740 a0ce4d412acead073f39d71919bfcb24 235 Pfam PF02811 PHP domain 6 123 1.6E-9 T 29-03-2018 IPR004013 PHP domain GO:0003824 HVS_RS06175 12ce17fdd8d5aaf0c7971c48b85622f1 390 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 136 176 2.8E-4 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat HVS_RS00645 58d73f2b23eac12835fdf0c12268e505 40 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 4 40 1.5E-13 T 29-03-2018 IPR009229 Staphylococcal AgrD HVS_RS09050 ac9187125dc1cc9369972765cbae27c4 267 Gene3D G3DSA:3.40.50.1820 13 267 3.1E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS09050 ac9187125dc1cc9369972765cbae27c4 267 SUPERFAMILY SSF53474 17 258 1.3E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS09050 ac9187125dc1cc9369972765cbae27c4 267 Pfam PF00756 Putative esterase 31 184 2.3E-27 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 HVS_RS13945 f64cdfe13ef548578eb527a627d30bff 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 295 1.7E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS13945 f64cdfe13ef548578eb527a627d30bff 296 Gene3D G3DSA:1.10.3720.10 8 296 4.4E-41 T 29-03-2018 HVS_RS13945 f64cdfe13ef548578eb527a627d30bff 296 SUPERFAMILY SSF161098 67 283 4.97E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS04135 7d40951bbec9e5e2428b337a598a733c 191 Gene3D G3DSA:2.60.60.30 19 183 4.2E-51 T 29-03-2018 HVS_RS04135 7d40951bbec9e5e2428b337a598a733c 191 Pfam PF02342 TerD domain 4 184 3.7E-60 T 29-03-2018 IPR003325 TerD domain GO:0006950 HVS_RS04195 3794173c8ea8870ced272af3309067b6 486 Gene3D G3DSA:2.115.10.20 34 486 5.4E-80 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS04195 3794173c8ea8870ced272af3309067b6 486 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 256 481 8.6E-36 T 29-03-2018 IPR007184 Mannoside phosphorylase HVS_RS04195 3794173c8ea8870ced272af3309067b6 486 SUPERFAMILY SSF75005 265 475 2.43E-57 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HVS_RS09825 7bde84c0ff56ed6e6e2a5a6c97bb305d 237 SUPERFAMILY SSF53448 7 234 1.03E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09825 7bde84c0ff56ed6e6e2a5a6c97bb305d 237 Gene3D G3DSA:3.90.550.10 8 236 1.6E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS09825 7bde84c0ff56ed6e6e2a5a6c97bb305d 237 Pfam PF00483 Nucleotidyl transferase 12 233 4.4E-35 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 Gene3D G3DSA:2.40.30.40 64 152 1.5E-22 T 29-03-2018 IPR023367 Peptidase M42, domain 2 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 Pfam PF05343 M42 glutamyl aminopeptidase 40 328 1.5E-93 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 SUPERFAMILY SSF53187 162 337 8.31E-62 T 29-03-2018 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 SUPERFAMILY SSF53187 2 75 8.31E-62 T 29-03-2018 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 SUPERFAMILY SSF101821 65 170 6.41E-23 T 29-03-2018 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 Gene3D G3DSA:3.40.630.10 164 343 2.4E-40 T 29-03-2018 HVS_RS07570 5b5a0d0de385396e5a3f460f27932acf 347 PIRSF PIRSF001123 1 341 3.5E-117 T 29-03-2018 IPR008007 Peptidase M42 HVS_RS10670 f60a6ef20c5e407f4cc95f2911ec134f 168 Pfam PF02620 Uncharacterized ACR, COG1399 55 161 1.5E-23 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD HVS_RS15805 d85de941b22ff186d5977b664a73018c 486 Gene3D G3DSA:3.40.190.10 206 486 1.4E-25 T 29-03-2018 HVS_RS15805 d85de941b22ff186d5977b664a73018c 486 SUPERFAMILY SSF53850 23 28 1.29E-34 T 29-03-2018 HVS_RS15805 d85de941b22ff186d5977b664a73018c 486 SUPERFAMILY SSF53850 69 478 1.29E-34 T 29-03-2018 HVS_RS15805 d85de941b22ff186d5977b664a73018c 486 Pfam PF01547 Bacterial extracellular solute-binding protein 107 396 4.1E-19 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 HVS_RS01400 424ab5172aa7d7ef0ab25cb468d3b8f0 166 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 142 26.955 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 HVS_RS01400 424ab5172aa7d7ef0ab25cb468d3b8f0 166 Pfam PF02623 FliW protein 19 139 1.4E-42 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 HVS_RS01400 424ab5172aa7d7ef0ab25cb468d3b8f0 166 SUPERFAMILY SSF141457 1 144 1.57E-50 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain HVS_RS01400 424ab5172aa7d7ef0ab25cb468d3b8f0 166 Gene3D G3DSA:2.30.290.10 1 149 4.8E-55 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain HVS_RS08255 44ecc16621ab22518be1ed654cad9db5 536 Pfam PF01943 Polysaccharide biosynthesis protein 7 306 2.7E-29 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HVS_RS08255 44ecc16621ab22518be1ed654cad9db5 536 PIRSF PIRSF038958 1 526 4.6E-106 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type HVS_RS08255 44ecc16621ab22518be1ed654cad9db5 536 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 359 508 2.1E-23 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HVS_RS05060 42086ad28a72288b4c53743ce3e7e6da 69 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 7.4E-15 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 HVS_RS03880 fe83534e075410418c1276eac3db1185 256 Pfam PF14319 Transposase zinc-binding domain 15 121 4.6E-24 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS03880 fe83534e075410418c1276eac3db1185 256 Pfam PF04986 Putative transposase 153 255 1.2E-12 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS03350 09ec90634e22849e33ea501d2f8a8605 174 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 2 162 1.4E-34 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 HVS_RS03350 09ec90634e22849e33ea501d2f8a8605 174 Gene3D G3DSA:3.20.19.10 2 174 7.1E-40 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HVS_RS03350 09ec90634e22849e33ea501d2f8a8605 174 Pfam PF00694 Aconitase C-terminal domain 52 112 1.4E-20 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 HVS_RS03350 09ec90634e22849e33ea501d2f8a8605 174 SUPERFAMILY SSF52016 2 173 3.14E-44 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 SMART SM00729 143 360 6.4E-59 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 Pfam PF00919 Uncharacterized protein family UPF0004 3 98 9.0E-27 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 425 1.9E-142 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 Pfam PF04055 Radical SAM superfamily 147 318 9.6E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 419 2.8E-142 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 Gene3D G3DSA:3.80.30.20 140 374 5.9E-51 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe HVS_RS11610 dc6a5565804512aab49f35d6b1f378c9 436 SUPERFAMILY SSF102114 127 364 3.01E-59 T 29-03-2018 HVS_RS01085 fb92a1ac73de2ec2a31cbbd846d793c0 58 Gene3D G3DSA:3.30.420.10 1 58 5.7E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS01085 fb92a1ac73de2ec2a31cbbd846d793c0 58 Pfam PF13333 Integrase core domain 1 46 5.5E-7 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS05660 fb92a1ac73de2ec2a31cbbd846d793c0 58 Gene3D G3DSA:3.30.420.10 1 58 5.7E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS05660 fb92a1ac73de2ec2a31cbbd846d793c0 58 Pfam PF13333 Integrase core domain 1 46 5.5E-7 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS14525 cd41b442d1be17bed08bb22483546821 227 Pfam PF07238 PilZ domain 122 216 1.2E-5 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS14525 cd41b442d1be17bed08bb22483546821 227 Gene3D G3DSA:2.40.10.220 102 220 8.4E-13 T 29-03-2018 HVS_RS07985 6aadadab5a939124f07a73f9bab7b59f 627 SUPERFAMILY SSF53795 235 278 1.1E-35 T 29-03-2018 HVS_RS07985 6aadadab5a939124f07a73f9bab7b59f 627 SUPERFAMILY SSF53795 307 610 1.1E-35 T 29-03-2018 HVS_RS07985 6aadadab5a939124f07a73f9bab7b59f 627 Pfam PF16260 Domain of unknown function (DUF4914) 12 623 0.0 T 29-03-2018 IPR032583 Protein of unknown function DUF4914 HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 Gene3D G3DSA:3.90.1530.10 15 117 9.0E-36 T 29-03-2018 HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 24 203 1.1E-60 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 Pfam PF02195 ParB-like nuclease domain 30 117 4.9E-26 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 SUPERFAMILY SSF109709 109 220 9.42E-37 T 29-03-2018 HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 SMART SM00470 28 117 9.1E-35 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 Gene3D G3DSA:1.10.10.730 118 165 1.5E-19 T 29-03-2018 HVS_RS00040 b22a3a32d6407f2adf5c390dfa7bfb3e 287 SUPERFAMILY SSF110849 28 119 3.92E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin HVS_RS12160 d270f2b26a085f2917a6e58bff061ebb 459 SUPERFAMILY SSF51569 49 349 1.36E-60 T 29-03-2018 HVS_RS12160 d270f2b26a085f2917a6e58bff061ebb 459 Gene3D G3DSA:3.20.20.70 34 390 5.5E-65 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS12160 d270f2b26a085f2917a6e58bff061ebb 459 Pfam PF00682 HMGL-like 56 331 1.3E-32 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 HVS_RS15470 c3bcb278e980f920198619a1206d7689 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 2.4E-59 T 29-03-2018 IPR023214 HAD-like domain HVS_RS15470 c3bcb278e980f920198619a1206d7689 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 257 3.0E-56 T 29-03-2018 IPR000150 Cof family GO:0016787 HVS_RS15470 c3bcb278e980f920198619a1206d7689 274 Gene3D G3DSA:3.40.50.1000 1 274 4.8E-38 T 29-03-2018 IPR023214 HAD-like domain HVS_RS15470 c3bcb278e980f920198619a1206d7689 274 SUPERFAMILY SSF56784 1 261 1.68E-59 T 29-03-2018 IPR023214 HAD-like domain HVS_RS15470 c3bcb278e980f920198619a1206d7689 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 241 3.2E-28 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 HVS_RS15470 c3bcb278e980f920198619a1206d7689 274 ProSitePatterns PS01229 Hypothetical cof family signature 2. 222 244 - T 29-03-2018 HVS_RS05335 c3454af1315060fd7b77752a2f6dee2a 159 SMART SM00260 1 147 2.6E-25 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS05335 c3454af1315060fd7b77752a2f6dee2a 159 Gene3D G3DSA:2.40.50.180 22 93 5.9E-17 T 29-03-2018 HVS_RS05335 c3454af1315060fd7b77752a2f6dee2a 159 Gene3D G3DSA:2.30.30.40 94 141 1.5E-12 T 29-03-2018 HVS_RS05335 c3454af1315060fd7b77752a2f6dee2a 159 Pfam PF01584 CheW-like domain 5 149 3.6E-30 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS05335 c3454af1315060fd7b77752a2f6dee2a 159 SUPERFAMILY SSF50341 4 150 2.49E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS14645 cf3dd338ae79113bda09107ed201ee61 226 Gene3D G3DSA:3.40.50.300 1 224 5.4E-28 T 29-03-2018 HVS_RS14645 cf3dd338ae79113bda09107ed201ee61 226 Pfam PF02223 Thymidylate kinase 11 196 1.3E-15 T 29-03-2018 HVS_RS14645 cf3dd338ae79113bda09107ed201ee61 226 SUPERFAMILY SSF52540 1 222 7.0E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03385 4e0b29416b0b7dad14465569011ec557 90 Pfam PF12791 Anti-sigma factor N-terminus 21 70 1.3E-13 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS08730 f192a71d41d5b0b23271542357f472ce 157 Gene3D G3DSA:2.30.30.40 87 132 4.0E-14 T 29-03-2018 HVS_RS08730 f192a71d41d5b0b23271542357f472ce 157 SMART SM00260 1 138 1.1E-30 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS08730 f192a71d41d5b0b23271542357f472ce 157 SUPERFAMILY SSF50341 3 142 1.15E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS08730 f192a71d41d5b0b23271542357f472ce 157 Gene3D G3DSA:2.40.50.180 22 86 1.6E-20 T 29-03-2018 HVS_RS08730 f192a71d41d5b0b23271542357f472ce 157 Pfam PF01584 CheW-like domain 5 141 9.9E-32 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Pfam PF00331 Glycosyl hydrolase family 10 224 488 1.3E-49 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Gene3D G3DSA:3.20.20.80 220 501 1.9E-42 T 29-03-2018 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 PRINTS PR00134 Glycosyl hydrolase family 10 signature 336 347 1.2E-6 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 PRINTS PR00134 Glycosyl hydrolase family 10 signature 402 414 1.2E-6 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 PRINTS PR00134 Glycosyl hydrolase family 10 signature 374 385 1.2E-6 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 PRINTS PR00134 Glycosyl hydrolase family 10 signature 292 304 1.2E-6 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 SUPERFAMILY SSF63446 579 652 2.65E-15 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Gene3D G3DSA:2.60.40.1120 502 580 3.4E-5 T 29-03-2018 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Pfam PF00404 Dockerin type I repeat 624 644 5.2E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Pfam PF00404 Dockerin type I repeat 584 604 3.1E-6 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 SUPERFAMILY SSF49785 30 178 3.61E-36 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 SUPERFAMILY SSF49464 514 568 2.55E-7 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 SMART SM00633 261 504 1.3E-11 T 29-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Gene3D G3DSA:2.60.120.260 25 191 3.0E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 SUPERFAMILY SSF51445 212 518 1.67E-91 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Pfam PF02018 Carbohydrate binding domain 32 164 9.7E-25 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 HVS_RS07945 c69d800f43f7b689ab0417f612ac8fb2 653 Gene3D G3DSA:1.10.1330.10 581 653 0.0014 T 29-03-2018 HVS_RS01530 d9f9b8040dd28fb6bcd111358ad01c6c 505 SUPERFAMILY SSF52200 34 104 3.27E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 HVS_RS01530 d9f9b8040dd28fb6bcd111358ad01c6c 505 Gene3D G3DSA:3.40.50.10140 32 184 5.4E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 HVS_RS01530 d9f9b8040dd28fb6bcd111358ad01c6c 505 Pfam PF08357 SEFIR domain 37 167 6.7E-20 T 29-03-2018 IPR013568 SEFIR domain HVS_RS00100 749135e7a5eb71df6a30334643e1cb12 106 Gene3D G3DSA:2.60.40.10 7 104 7.8E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00100 749135e7a5eb71df6a30334643e1cb12 106 Pfam PF10704 Protein of unknown function (DUF2508) 42 100 2.2E-10 T 29-03-2018 IPR019644 Protein of unknown function DUF2508 HVS_RS11005 7a0aa26195c62ea54e7a9e34f9c18aa1 444 Gene3D G3DSA:1.10.287.950 332 431 6.5E-7 T 29-03-2018 HVS_RS11005 7a0aa26195c62ea54e7a9e34f9c18aa1 444 Pfam PF02743 Cache domain 39 270 7.3E-19 T 29-03-2018 IPR033479 Double Cache domain 1 HVS_RS11005 7a0aa26195c62ea54e7a9e34f9c18aa1 444 Gene3D G3DSA:3.30.450.20 159 287 1.0E-19 T 29-03-2018 HVS_RS11005 7a0aa26195c62ea54e7a9e34f9c18aa1 444 Gene3D G3DSA:3.30.450.20 46 158 6.5E-10 T 29-03-2018 HVS_RS11005 7a0aa26195c62ea54e7a9e34f9c18aa1 444 SUPERFAMILY SSF58104 340 440 1.88E-7 T 29-03-2018 HVS_RS03445 5b1c03e7c9de5b54037645a9f4779878 512 Gene3D G3DSA:2.130.10.130 65 511 1.3E-7 T 29-03-2018 HVS_RS03445 5b1c03e7c9de5b54037645a9f4779878 512 SUPERFAMILY SSF69318 389 505 3.14E-7 T 29-03-2018 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 Pfam PF04851 Type III restriction enzyme, res subunit 272 455 1.2E-15 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 9 712 1.8E-194 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 SMART SM00487 264 486 8.8E-12 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 Pfam PF11867 Domain of unknown function (DUF3387) 710 1038 3.7E-123 T 29-03-2018 IPR021810 Protein of unknown function DUF3387 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 213 7.0E-42 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 Gene3D G3DSA:3.40.50.300 530 711 1.2E-5 T 29-03-2018 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 Gene3D G3DSA:3.40.50.300 36 477 9.1E-27 T 29-03-2018 HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 SUPERFAMILY SSF52540 614 694 3.13E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 SUPERFAMILY SSF52540 404 487 3.13E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 SUPERFAMILY SSF52540 546 584 3.13E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS01550 9f74c0029e0fb3781712fba373fafe49 1065 SUPERFAMILY SSF52540 227 502 2.98E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04690 937894709b15f9cf4a81e4652f77bcc5 140 Gene3D G3DSA:3.40.190.10 2 137 2.5E-4 T 29-03-2018 HVS_RS06020 a9659f0adfed3da3fdb66c1d07443073 191 Hamap MF_01515 UPF0316 protein . 2 170 29.233 T 29-03-2018 IPR022930 Protein of unknown function UPF0316 HVS_RS06020 a9659f0adfed3da3fdb66c1d07443073 191 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 110 160 1.0E-10 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 HVS_RS14805 a9659f0adfed3da3fdb66c1d07443073 191 Hamap MF_01515 UPF0316 protein . 2 170 29.233 T 29-03-2018 IPR022930 Protein of unknown function UPF0316 HVS_RS14805 a9659f0adfed3da3fdb66c1d07443073 191 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 110 160 1.0E-10 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 HVS_RS15670 8807a7312db3bf260db9d89f899d9bc2 164 Pfam PF02810 SEC-C motif 146 164 9.5E-11 T 29-03-2018 IPR004027 SEC-C motif HVS_RS15670 8807a7312db3bf260db9d89f899d9bc2 164 SUPERFAMILY SSF103642 143 163 3.6E-8 T 29-03-2018 HVS_RS15670 8807a7312db3bf260db9d89f899d9bc2 164 Gene3D G3DSA:3.10.450.50 6 164 5.7E-19 T 29-03-2018 HVS_RS08510 c8d654ba6155cffd62cf919721ca4122 125 Gene3D G3DSA:1.10.10.10 1 78 6.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08510 c8d654ba6155cffd62cf919721ca4122 125 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 6.3E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS08510 c8d654ba6155cffd62cf919721ca4122 125 SUPERFAMILY SSF46785 6 80 1.45E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS08510 c8d654ba6155cffd62cf919721ca4122 125 SMART SM00345 17 76 1.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 8.3E-73 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 Gene3D G3DSA:2.40.50.140 1 63 2.0E-18 T 29-03-2018 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 Pfam PF03193 RsgA GTPase 61 225 9.6E-57 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 290 35.629 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 SUPERFAMILY SSF52540 67 284 1.63E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 Gene3D G3DSA:1.10.40.50 227 295 2.1E-19 T 29-03-2018 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 Gene3D G3DSA:3.40.50.300 64 225 2.6E-29 T 29-03-2018 HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 Pfam PF16745 RsgA N-terminal domain 4 56 1.0E-17 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal HVS_RS07070 70e83d5a9a153399f3e00a4bc2c60028 295 SUPERFAMILY SSF50249 2 64 4.86E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS09475 30060079eb7bce80d30f753a3843d9fa 328 Pfam PF01944 Stage II sporulation protein M 114 286 2.0E-35 T 29-03-2018 IPR002798 Stage II sporulation protein M-like HVS_RS10645 7a0b9e9fddd1f2c352e4c83e1c62c805 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 2.4E-243 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 HVS_RS10645 7a0b9e9fddd1f2c352e4c83e1c62c805 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 2.1E-238 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 HVS_RS10645 7a0b9e9fddd1f2c352e4c83e1c62c805 492 Gene3D G3DSA:3.40.50.300 3 260 1.0E-14 T 29-03-2018 HVS_RS10645 7a0b9e9fddd1f2c352e4c83e1c62c805 492 SUPERFAMILY SSF52540 18 233 3.78E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10645 7a0b9e9fddd1f2c352e4c83e1c62c805 492 PIRSF PIRSF007466 1 492 8.3E-261 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 HVS_RS13590 14ef34fc6b1d2a9a890471d2ccda4b89 95 SMART SM00990 1 83 1.9E-11 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 HVS_RS13590 14ef34fc6b1d2a9a890471d2ccda4b89 95 Pfam PF08774 VRR-NUC domain 31 82 3.1E-5 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 HVS_RS13590 14ef34fc6b1d2a9a890471d2ccda4b89 95 SUPERFAMILY SSF52980 9 91 1.79E-13 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 HVS_RS13590 14ef34fc6b1d2a9a890471d2ccda4b89 95 Gene3D G3DSA:3.40.1350.10 11 80 3.3E-4 T 29-03-2018 HVS_RS00795 14cbd27369a8f5810611be9ecd1086aa 153 SUPERFAMILY SSF52540 5 145 3.1E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00795 14cbd27369a8f5810611be9ecd1086aa 153 Pfam PF13401 AAA domain 10 57 6.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS14270 3ace75414932be433fa7189de9a9d114 289 SUPERFAMILY SSF48371 94 189 6.4E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 HVS_RS14270 3ace75414932be433fa7189de9a9d114 289 Gene3D G3DSA:1.25.40.70 73 177 0.0027 T 29-03-2018 HVS_RS13010 d241b88868ea3a0609a98005b655330a 390 Gene3D G3DSA:2.130.10.10 313 390 0.01 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS13010 d241b88868ea3a0609a98005b655330a 390 Gene3D G3DSA:2.130.10.10 59 312 0.012 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 HVS_RS13010 d241b88868ea3a0609a98005b655330a 390 SUPERFAMILY SSF69304 119 358 5.36E-6 T 29-03-2018 HVS_RS10125 32e859a322ca580a7994c2414c2bff0f 206 SUPERFAMILY SSF103039 6 204 1.19E-55 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10125 32e859a322ca580a7994c2414c2bff0f 206 Gene3D G3DSA:3.40.1550.10 5 206 1.8E-54 T 29-03-2018 IPR028976 CheC-like domain HVS_RS10125 32e859a322ca580a7994c2414c2bff0f 206 Pfam PF04509 CheC-like family 13 47 6.3E-14 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 HVS_RS10125 32e859a322ca580a7994c2414c2bff0f 206 Pfam PF04509 CheC-like family 110 145 9.7E-11 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 HVS_RS04950 d4702b43faf62c05d229c0c38a575d11 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 13.621 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HVS_RS04950 d4702b43faf62c05d229c0c38a575d11 87 SUPERFAMILY SSF143430 2 81 1.27E-23 T 29-03-2018 HVS_RS04950 d4702b43faf62c05d229c0c38a575d11 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 2 79 2.3E-10 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HVS_RS04950 d4702b43faf62c05d229c0c38a575d11 87 Pfam PF09827 CRISPR associated protein Cas2 2 71 9.7E-18 T 29-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 HVS_RS04950 d4702b43faf62c05d229c0c38a575d11 87 Gene3D G3DSA:3.30.70.240 1 66 5.9E-20 T 29-03-2018 HVS_RS15850 2f5d12ca07a9a9ddc855366558317bf0 250 Pfam PF13566 Domain of unknown function (DUF4130 85 243 1.6E-48 T 29-03-2018 IPR025404 Domain of unknown function DUF4130 HVS_RS15850 2f5d12ca07a9a9ddc855366558317bf0 250 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 4 244 3.4E-76 T 29-03-2018 IPR023875 DNA metabolism protein, putative HVS_RS14320 ceb8e1b922d53f641341be3876bc3486 166 Pfam PF13930 DNA/RNA non-specific endonuclease 55 139 1.6E-21 T 29-03-2018 HVS_RS09200 5520f61408da4f6c8e1323d200da3b0d 223 SUPERFAMILY SSF47781 31 79 2.74E-8 T 29-03-2018 IPR010994 RuvA domain 2-like HVS_RS09200 5520f61408da4f6c8e1323d200da3b0d 223 Pfam PF04002 RadC-like JAB domain 101 220 6.3E-39 T 29-03-2018 IPR025657 RadC-like JAB domain HVS_RS09200 5520f61408da4f6c8e1323d200da3b0d 223 Gene3D G3DSA:3.40.140.10 96 221 7.8E-39 T 29-03-2018 HVS_RS09200 5520f61408da4f6c8e1323d200da3b0d 223 Gene3D G3DSA:1.10.150.20 40 80 5.9E-6 T 29-03-2018 HVS_RS09200 5520f61408da4f6c8e1323d200da3b0d 223 TIGRFAM TIGR00608 radc: DNA repair protein RadC 9 221 1.1E-49 T 29-03-2018 IPR001405 RadC protein HVS_RS12735 85590e6f5c610eb8bfe63c02a5f2a9fc 394 Pfam PF13616 PPIC-type PPIASE domain 221 346 1.2E-14 T 29-03-2018 HVS_RS12735 85590e6f5c610eb8bfe63c02a5f2a9fc 394 SUPERFAMILY SSF109998 40 249 1.14E-15 T 29-03-2018 IPR027304 Trigger factor/SurA domain HVS_RS12735 85590e6f5c610eb8bfe63c02a5f2a9fc 394 SUPERFAMILY SSF54534 221 346 6.41E-14 T 29-03-2018 HVS_RS12735 85590e6f5c610eb8bfe63c02a5f2a9fc 394 Pfam PF13623 SurA N-terminal domain 2 126 5.3E-13 T 29-03-2018 HVS_RS12735 85590e6f5c610eb8bfe63c02a5f2a9fc 394 Gene3D G3DSA:1.10.4030.10 33 190 1.9E-9 T 29-03-2018 HVS_RS12735 85590e6f5c610eb8bfe63c02a5f2a9fc 394 Gene3D G3DSA:3.10.50.40 219 371 1.2E-24 T 29-03-2018 HVS_RS01325 80b1ed7ae6c412c9cba515d179cde587 179 SUPERFAMILY SSF53271 3 177 2.23E-57 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS01325 80b1ed7ae6c412c9cba515d179cde587 179 Gene3D G3DSA:3.40.50.2020 1 179 5.0E-48 T 29-03-2018 HVS_RS01325 80b1ed7ae6c412c9cba515d179cde587 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 1.4E-64 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 HVS_RS01325 80b1ed7ae6c412c9cba515d179cde587 179 Pfam PF00156 Phosphoribosyl transferase domain 16 159 4.6E-30 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HVS_RS00015 69d6d5791f9855694b5452375623aad8 69 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 60 3.8E-25 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA HVS_RS00015 69d6d5791f9855694b5452375623aad8 69 Gene3D G3DSA:3.10.290.10 1 69 7.0E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 HVS_RS00015 69d6d5791f9855694b5452375623aad8 69 SUPERFAMILY SSF55174 2 67 2.62E-19 T 29-03-2018 HVS_RS00015 69d6d5791f9855694b5452375623aad8 69 Pfam PF13275 S4 domain 4 68 5.2E-28 T 29-03-2018 HVS_RS09770 f1cc8d7145a5ba3f48eb8db9304443e7 578 Pfam PF13360 PQQ-like domain 484 576 1.1E-4 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat HVS_RS09770 f1cc8d7145a5ba3f48eb8db9304443e7 578 Gene3D G3DSA:2.140.10.10 451 578 1.5E-13 T 29-03-2018 HVS_RS09770 f1cc8d7145a5ba3f48eb8db9304443e7 578 SUPERFAMILY SSF50998 296 572 6.8E-21 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily HVS_RS09770 f1cc8d7145a5ba3f48eb8db9304443e7 578 Gene3D G3DSA:2.140.10.10 120 450 1.6E-21 T 29-03-2018 HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 Gene3D G3DSA:1.10.455.10 6 156 1.3E-62 T 29-03-2018 IPR023798 Ribosomal protein S7 domain HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 SUPERFAMILY SSF47973 6 149 2.88E-64 T 29-03-2018 IPR023798 Ribosomal protein S7 domain HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 Pfam PF00177 Ribosomal protein S7p/S5e 2 149 6.6E-69 T 29-03-2018 IPR023798 Ribosomal protein S7 domain HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 PIRSF PIRSF002122 4 156 7.0E-62 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.483 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HVS_RS12935 fa25cf88dd6872eb02b703a684a5220e 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.3E-71 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HVS_RS15570 0a9f2ad89458fec7e23f7fc417c00da9 274 Pfam PF02535 ZIP Zinc transporter 6 269 1.3E-21 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HVS_RS00370 239ae43af1b6e6ed42bb6c06e17094ae 355 SUPERFAMILY SSF55729 54 103 9.09E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS00370 239ae43af1b6e6ed42bb6c06e17094ae 355 SUPERFAMILY SSF55729 131 323 9.09E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS00370 239ae43af1b6e6ed42bb6c06e17094ae 355 Gene3D G3DSA:3.40.630.30 156 328 8.7E-6 T 29-03-2018 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 SUPERFAMILY SSF56601 8 273 4.9E-62 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 253 2.7E-56 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 Gene3D G3DSA:2.60.410.10 285 360 0.0018 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 SUPERFAMILY SSF69189 265 358 6.67E-8 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 153 2.5E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 130 2.5E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 63 74 2.5E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HVS_RS06450 dd204ced8aa95e0b7dcfb1bf2b6b1422 415 Gene3D G3DSA:3.40.710.10 23 284 7.9E-41 T 29-03-2018 HVS_RS05555 4073c5b113580f4254d26cae1caf2075 546 Pfam PF00498 FHA domain 469 534 1.3E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 HVS_RS05555 4073c5b113580f4254d26cae1caf2075 546 Gene3D G3DSA:2.60.200.20 345 546 7.3E-24 T 29-03-2018 HVS_RS05555 4073c5b113580f4254d26cae1caf2075 546 SMART SM00240 467 518 5.0E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 HVS_RS05555 4073c5b113580f4254d26cae1caf2075 546 SUPERFAMILY SSF49879 448 543 1.42E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 HVS_RS08925 bf206626730aaeac6de895d4345247a5 146 Pfam PF12670 Protein of unknown function (DUF3792) 19 131 1.2E-24 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane HVS_RS08925 bf206626730aaeac6de895d4345247a5 146 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 22 134 1.7E-27 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane HVS_RS12490 6d40695a2c2b640abc697976665c766f 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 24 476 1.1E-89 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 SMART SM00997 183 344 3.0E-105 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 SUPERFAMILY SSF52283 2 182 7.94E-96 T 29-03-2018 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 SUPERFAMILY SSF52283 345 412 7.94E-96 T 29-03-2018 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 PIRSF PIRSF001109 1 413 6.3E-185 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 2 412 2.7E-188 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Gene3D G3DSA:3.40.50.1480 197 397 5.8E-63 T 29-03-2018 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 183 342 1.4E-53 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 SMART SM00996 1 413 5.3E-126 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 412 45.807 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Gene3D G3DSA:3.40.50.1480 136 196 1.4E-14 T 29-03-2018 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Gene3D G3DSA:3.40.50.1480 1 135 2.2E-47 T 29-03-2018 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 73 87 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 133 7.2E-33 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 137 410 1.0E-21 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 205 221 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 HVS_RS12245 c590f22589f8bc279b1947ed290dbc24 413 SUPERFAMILY SSF51735 183 345 1.32E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15585 681e529d1e9feff02cddb3f66c0b6643 122 Gene3D G3DSA:1.10.10.60 43 81 3.4E-5 T 29-03-2018 HVS_RS15585 681e529d1e9feff02cddb3f66c0b6643 122 Pfam PF09862 Protein of unknown function (DUF2089) 9 121 1.0E-45 T 29-03-2018 IPR018658 Protein of unknown function DUF2089 HVS_RS11590 058a9b82624ebcd8483fd7d14d0cbeb3 96 Hamap MF_01448 UPF0473 protein . 5 89 12.638 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 HVS_RS11590 058a9b82624ebcd8483fd7d14d0cbeb3 96 Pfam PF06949 Protein of unknown function (DUF1292) 14 88 2.3E-18 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 HVS_RS04580 2aab80d5fc4fb96295441292426fcf95 360 Pfam PF00589 Phage integrase family 182 340 3.4E-43 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS04580 2aab80d5fc4fb96295441292426fcf95 360 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 82 157 2.3E-13 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HVS_RS04580 2aab80d5fc4fb96295441292426fcf95 360 SUPERFAMILY SSF56349 87 342 7.65E-58 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HVS_RS04580 2aab80d5fc4fb96295441292426fcf95 360 Gene3D G3DSA:1.10.150.130 71 158 1.2E-11 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal HVS_RS04580 2aab80d5fc4fb96295441292426fcf95 360 Gene3D G3DSA:1.10.443.10 177 342 1.2E-44 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS02130 591a29892e28098de344876cede8fa59 232 Pfam PF00005 ABC transporter 19 152 1.6E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS02130 591a29892e28098de344876cede8fa59 232 Gene3D G3DSA:3.40.50.300 1 230 6.8E-45 T 29-03-2018 HVS_RS02130 591a29892e28098de344876cede8fa59 232 SMART SM00382 27 201 5.7E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02130 591a29892e28098de344876cede8fa59 232 SUPERFAMILY SSF52540 2 211 1.43E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02130 591a29892e28098de344876cede8fa59 232 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS08960 dcbd9651c9ea6ea26f893839d46c428d 372 Gene3D G3DSA:3.20.20.105 1 371 6.9E-160 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HVS_RS08960 dcbd9651c9ea6ea26f893839d46c428d 372 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 1.6E-91 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HVS_RS08960 dcbd9651c9ea6ea26f893839d46c428d 372 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 370 9.6E-167 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HVS_RS08960 dcbd9651c9ea6ea26f893839d46c428d 372 SUPERFAMILY SSF51713 3 368 9.94E-161 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HVS_RS08960 dcbd9651c9ea6ea26f893839d46c428d 372 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 371 3.0E-175 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HVS_RS08960 dcbd9651c9ea6ea26f893839d46c428d 372 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.458 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 HVS_RS10945 8e4b5947ba36fbdef0da0947a6556426 144 Pfam PF01475 Ferric uptake regulator family 12 135 1.4E-39 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HVS_RS10945 8e4b5947ba36fbdef0da0947a6556426 144 Gene3D G3DSA:1.10.10.10 6 95 1.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS10945 8e4b5947ba36fbdef0da0947a6556426 144 SUPERFAMILY SSF46785 5 140 4.02E-42 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02250 5b7891c4435c82beaac5726ea4bb65e5 372 Pfam PF02163 Peptidase family M50 56 150 1.9E-9 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 HVS_RS02250 5b7891c4435c82beaac5726ea4bb65e5 372 Gene3D G3DSA:1.25.40.10 206 358 7.5E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HVS_RS00580 421729aa2527d237ceb44d9104238efc 93 Pfam PF04977 Septum formation initiator 15 91 7.7E-14 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 HVS_RS07735 a92092c3939ef24766404b8537cec3b6 60 Gene3D G3DSA:1.10.4040.10 6 48 1.6E-12 T 29-03-2018 HVS_RS07735 a92092c3939ef24766404b8537cec3b6 60 Pfam PF03965 Penicillinase repressor 3 46 1.2E-5 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HVS_RS07735 a92092c3939ef24766404b8537cec3b6 60 SUPERFAMILY SSF46785 2 54 4.72E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 SUPERFAMILY SSF51735 3 150 5.25E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 PIRSF PIRSF025648 2 328 1.7E-139 T 29-03-2018 IPR010190 Diaminopimelate dehydrogenase, Ddh GO:0009089|GO:0047850 KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 Gene3D G3DSA:3.40.50.720 2 137 3.5E-12 T 29-03-2018 HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 TIGRFAM TIGR01921 DAP-DH: diaminopimelate dehydrogenase 3 328 7.6E-141 T 29-03-2018 IPR010190 Diaminopimelate dehydrogenase, Ddh GO:0009089|GO:0047850 KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 SUPERFAMILY SSF55347 125 276 8.5E-57 T 29-03-2018 HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 Pfam PF16654 Diaminopimelic acid dehydrogenase C-terminal domain 124 277 3.4E-77 T 29-03-2018 IPR032094 Meso-diaminopimelate D-dehydrogenase, C-terminal KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 HVS_RS15915 411052c7ba7a2e8a7629ae35d3495987 328 Gene3D G3DSA:3.30.360.10 138 271 2.8E-66 T 29-03-2018 HVS_RS07415 d2ef403c59dbf54623279588b8fbb2c0 234 Pfam PF01219 Prokaryotic diacylglycerol kinase 12 112 1.0E-33 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 HVS_RS07415 d2ef403c59dbf54623279588b8fbb2c0 234 Gene3D G3DSA:1.10.3830.10 2 114 1.1E-37 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 HVS_RS07415 d2ef403c59dbf54623279588b8fbb2c0 234 SMART SM00014 127 228 0.0031 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS07415 d2ef403c59dbf54623279588b8fbb2c0 234 SUPERFAMILY SSF48317 42 232 4.84E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS07415 d2ef403c59dbf54623279588b8fbb2c0 234 Pfam PF01569 PAP2 superfamily 157 233 3.4E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HVS_RS10750 2b1642455bea363158e9a99287c4c966 417 Pfam PF07670 Nucleoside recognition 51 136 3.1E-6 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HVS_RS10750 2b1642455bea363158e9a99287c4c966 417 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 23 399 3.2E-99 T 29-03-2018 IPR014226 Sporulation integral membrane protein YlbJ HVS_RS09870 82c6aa48579a79199e6a00e595e387f8 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.0E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HVS_RS09870 82c6aa48579a79199e6a00e595e387f8 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HVS_RS09870 82c6aa48579a79199e6a00e595e387f8 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HVS_RS09870 82c6aa48579a79199e6a00e595e387f8 188 Gene3D G3DSA:1.10.10.60 5 48 1.9E-16 T 29-03-2018 HVS_RS09870 82c6aa48579a79199e6a00e595e387f8 188 SUPERFAMILY SSF46689 3 77 4.39E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 HVS_RS09870 82c6aa48579a79199e6a00e595e387f8 188 Gene3D G3DSA:1.10.10.60 49 164 4.7E-10 T 29-03-2018 HVS_RS08370 612ca0f8db43f42a0699f91445d893fb 76 SUPERFAMILY SSF54814 8 61 7.85E-8 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 HVS_RS08370 612ca0f8db43f42a0699f91445d893fb 76 Gene3D G3DSA:3.30.300.20 1 75 2.2E-17 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta HVS_RS08370 612ca0f8db43f42a0699f91445d893fb 76 Pfam PF13083 KH domain 2 74 6.3E-26 T 29-03-2018 HVS_RS08370 612ca0f8db43f42a0699f91445d893fb 76 Hamap MF_00088 UPF0109 protein . 1 75 24.281 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 HVS_RS09020 da06646bc98d313bdc1268ba9631d4f8 453 Gene3D G3DSA:1.10.287.510 348 447 0.004 T 29-03-2018 HVS_RS09020 da06646bc98d313bdc1268ba9631d4f8 453 Gene3D G3DSA:1.20.58.130 91 167 0.024 T 29-03-2018 HVS_RS09020 da06646bc98d313bdc1268ba9631d4f8 453 Gene3D G3DSA:1.20.58.130 253 329 1.3E-4 T 29-03-2018 HVS_RS09020 da06646bc98d313bdc1268ba9631d4f8 453 Gene3D G3DSA:1.20.58.130 35 86 0.22 T 29-03-2018 HVS_RS09020 da06646bc98d313bdc1268ba9631d4f8 453 Gene3D G3DSA:1.20.58.130 172 248 4.5E-4 T 29-03-2018 HVS_RS08860 5d3306ab0006ef12950c3d8325c8868c 543 Gene3D G3DSA:3.40.50.300 13 281 6.3E-20 T 29-03-2018 HVS_RS08860 5d3306ab0006ef12950c3d8325c8868c 543 SUPERFAMILY SSF52540 14 116 3.63E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08860 5d3306ab0006ef12950c3d8325c8868c 543 Gene3D G3DSA:1.10.287.510 465 543 5.0E-4 T 29-03-2018 HVS_RS08860 5d3306ab0006ef12950c3d8325c8868c 543 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 189 541 7.0E-8 T 29-03-2018 HVS_RS08860 5d3306ab0006ef12950c3d8325c8868c 543 SUPERFAMILY SSF75712 475 541 4.45E-8 T 29-03-2018 HVS_RS16190 67541c6878c8eb5ba9704ba64ab1d3e5 292 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 27 284 1.2E-56 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal HVS_RS16190 67541c6878c8eb5ba9704ba64ab1d3e5 292 Pfam PF02096 60Kd inner membrane protein 27 284 2.3E-56 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HVS_RS03195 b931b13c5d24ee027f22c250a21ad91f 704 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 286 1.2E-51 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 HVS_RS03195 b931b13c5d24ee027f22c250a21ad91f 704 Gene3D G3DSA:3.40.50.300 287 647 6.8E-47 T 29-03-2018 HVS_RS03195 b931b13c5d24ee027f22c250a21ad91f 704 Pfam PF13361 UvrD-like helicase C-terminal domain 292 620 2.4E-43 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HVS_RS03195 b931b13c5d24ee027f22c250a21ad91f 704 SUPERFAMILY SSF52540 8 440 1.63E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03195 b931b13c5d24ee027f22c250a21ad91f 704 SUPERFAMILY SSF52540 471 627 1.63E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03195 b931b13c5d24ee027f22c250a21ad91f 704 Gene3D G3DSA:3.40.50.300 5 286 4.4E-50 T 29-03-2018 HVS_RS00045 4ac3e9b447a0dfbdce25921128ada869 179 Pfam PF14584 Protein of unknown function (DUF4446) 19 166 4.0E-49 T 29-03-2018 IPR027981 Protein of unknown function DUF4446 HVS_RS13790 d308c5e6113374da047a92fd53ec40f9 117 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 34 106 1.6E-8 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core HVS_RS13790 d308c5e6113374da047a92fd53ec40f9 117 Gene3D G3DSA:1.10.287.1080 1 115 1.6E-16 T 29-03-2018 HVS_RS13790 d308c5e6113374da047a92fd53ec40f9 117 SUPERFAMILY SSF101386 5 107 1.78E-18 T 29-03-2018 HVS_RS13625 327db08569a134bcda5c77184019745a 209 Gene3D G3DSA:3.40.50.300 6 178 1.9E-17 T 29-03-2018 HVS_RS13625 327db08569a134bcda5c77184019745a 209 Pfam PF01695 IstB-like ATP binding protein 28 175 4.6E-53 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 HVS_RS13625 327db08569a134bcda5c77184019745a 209 SUPERFAMILY SSF52540 40 174 5.48E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13625 327db08569a134bcda5c77184019745a 209 PIRSF PIRSF003073 16 193 5.4E-61 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein HVS_RS13625 327db08569a134bcda5c77184019745a 209 SMART SM00382 43 178 1.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS13625 327db08569a134bcda5c77184019745a 209 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 134 148 4.2E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS13625 327db08569a134bcda5c77184019745a 209 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 47 65 4.2E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 HVS_RS13405 807ae5cc9b18b456b99a0caeab4a3699 351 Pfam PF14897 EpsG family 34 348 2.5E-51 T 29-03-2018 HVS_RS10595 4a51eed8edac8b5f79193baf17bc3ad4 153 Pfam PF14270 Domain of unknown function (DUF4358) 43 137 9.0E-24 T 29-03-2018 IPR025648 Protein of unknown function DUF4358 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 Pfam PF00453 Ribosomal protein L20 3 109 7.4E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.5E-51 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 Gene3D G3DSA:1.10.1900.20 55 116 4.0E-32 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 SUPERFAMILY SSF74731 3 116 1.96E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 70 1.0E-19 T 29-03-2018 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.696 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.4E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.4E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS06405 0223da6d600b39f0699044b1aa584e2c 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.4E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS08430 2b99625ea746c1bce7b52c6c1a1fe93d 128 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 3 108 3.0E-19 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA HVS_RS08430 2b99625ea746c1bce7b52c6c1a1fe93d 128 Gene3D G3DSA:1.20.1500.10 2 111 1.3E-19 T 29-03-2018 IPR023378 YheA/YmcA-like domain HVS_RS08430 2b99625ea746c1bce7b52c6c1a1fe93d 128 SUPERFAMILY SSF158622 1 112 3.79E-21 T 29-03-2018 IPR023378 YheA/YmcA-like domain HVS_RS14090 924988130e9981705ce3a5d7ade89531 322 Gene3D G3DSA:3.40.50.300 29 195 9.7E-28 T 29-03-2018 HVS_RS14090 924988130e9981705ce3a5d7ade89531 322 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 48 178 1.2E-64 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 HVS_RS14090 924988130e9981705ce3a5d7ade89531 322 PIRSF PIRSF002849 1 322 4.6E-135 T 29-03-2018 HVS_RS14090 924988130e9981705ce3a5d7ade89531 322 Gene3D G3DSA:1.10.8.300 210 319 1.4E-34 T 29-03-2018 HVS_RS14090 924988130e9981705ce3a5d7ade89531 322 SUPERFAMILY SSF52540 13 295 4.02E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03780 6c461852307630b6bdfd2481b2f9237d 418 Pfam PF01548 Transposase 21 177 1.2E-20 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HVS_RS03780 6c461852307630b6bdfd2481b2f9237d 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 284 373 1.8E-22 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HVS_RS03710 d39f49aeeee92987b38a4eba99f20ee6 97 Pfam PF16138 Domain of unknown function (4846) 1 96 1.2E-33 T 29-03-2018 IPR032315 Protein of unknown function DUF4846 HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 153 247 1.5E-24 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 137 5.6E-44 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 188 264 1.5E-23 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 Pfam PF00460 Flagella basal body rod protein 5 35 2.9E-13 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 264 6.5E-78 T 29-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 SUPERFAMILY SSF117143 90 226 2.35E-28 T 29-03-2018 HVS_RS00495 3a031e316d25aa9f8d49c60c6dc278b9 266 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site HVS_RS15020 c3697fa202b7f3050dd8369169053f46 72 SMART SM00316 4 72 1.8E-7 T 29-03-2018 IPR022967 RNA-binding domain, S1 HVS_RS15020 c3697fa202b7f3050dd8369169053f46 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.1E-38 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HVS_RS15020 c3697fa202b7f3050dd8369169053f46 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.618 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HVS_RS15020 c3697fa202b7f3050dd8369169053f46 72 Gene3D G3DSA:2.40.50.140 1 72 3.8E-38 T 29-03-2018 HVS_RS15020 c3697fa202b7f3050dd8369169053f46 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.5E-30 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 HVS_RS15020 c3697fa202b7f3050dd8369169053f46 72 SUPERFAMILY SSF50249 2 70 3.18E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold HVS_RS12285 c7a6e9c2f607ec2ccfbc8497982173d2 347 SUPERFAMILY SSF69304 152 315 2.48E-12 T 29-03-2018 HVS_RS12285 c7a6e9c2f607ec2ccfbc8497982173d2 347 Pfam PF16472 Domain of unknown function (DUF5050) 138 345 1.5E-18 T 29-03-2018 IPR032485 Domain of unknown function DUF5050 HVS_RS12285 c7a6e9c2f607ec2ccfbc8497982173d2 347 Gene3D G3DSA:2.140.10.30 102 310 1.1E-8 T 29-03-2018 HVS_RS04875 f0d4c6197599361b8ea558d2d580e55e 286 Pfam PF04909 Amidohydrolase 71 284 2.9E-31 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 HVS_RS04875 f0d4c6197599361b8ea558d2d580e55e 286 Gene3D G3DSA:3.20.20.140 3 286 2.1E-40 T 29-03-2018 HVS_RS04875 f0d4c6197599361b8ea558d2d580e55e 286 SUPERFAMILY SSF51556 6 284 1.52E-42 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS05860 668113652e80fa54aac9ad8e57906a49 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 HVS_RS05860 668113652e80fa54aac9ad8e57906a49 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 4 52 2.6E-19 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HVS_RS13655 9b9f9d52682961f5eba193a924a8859a 546 Gene3D G3DSA:3.40.50.10770 66 215 4.0E-8 T 29-03-2018 HVS_RS01050 3b4479534dda1eb4cc3a4c8b94a7db1d 287 Gene3D G3DSA:3.30.457.10 128 204 6.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01050 3b4479534dda1eb4cc3a4c8b94a7db1d 287 Gene3D G3DSA:3.30.457.10 6 65 2.8E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01050 3b4479534dda1eb4cc3a4c8b94a7db1d 287 Gene3D G3DSA:3.30.457.10 66 127 1.4E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01050 3b4479534dda1eb4cc3a4c8b94a7db1d 287 SUPERFAMILY SSF55383 56 139 1.07E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01050 3b4479534dda1eb4cc3a4c8b94a7db1d 287 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 4.8E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS00160 c597ebe6af140c0e50af728c94ec3600 66 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 3 54 6.0E-15 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS00160 c597ebe6af140c0e50af728c94ec3600 66 Pfam PF05582 YabG peptidase U57 4 63 6.1E-17 T 29-03-2018 IPR008764 Peptidase U57, YabG HVS_RS13955 6071df65f06115aa1f29b7f4ec891629 272 SUPERFAMILY SSF53335 5 193 6.87E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13955 6071df65f06115aa1f29b7f4ec891629 272 Pfam PF13847 Methyltransferase domain 57 169 1.9E-22 T 29-03-2018 IPR025714 Methyltransferase domain HVS_RS13955 6071df65f06115aa1f29b7f4ec891629 272 Gene3D G3DSA:3.40.50.150 3 189 6.1E-25 T 29-03-2018 HVS_RS06015 c3adfbe76cd051597adbd6b53ffef5ec 320 Gene3D G3DSA:3.40.50.1820 64 320 2.5E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS06015 c3adfbe76cd051597adbd6b53ffef5ec 320 SUPERFAMILY SSF53474 29 310 5.45E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS06015 c3adfbe76cd051597adbd6b53ffef5ec 320 Pfam PF12146 Serine aminopeptidase, S33 88 218 3.6E-10 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 HVS_RS14810 c3adfbe76cd051597adbd6b53ffef5ec 320 Gene3D G3DSA:3.40.50.1820 64 320 2.5E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS14810 c3adfbe76cd051597adbd6b53ffef5ec 320 SUPERFAMILY SSF53474 29 310 5.45E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS14810 c3adfbe76cd051597adbd6b53ffef5ec 320 Pfam PF12146 Serine aminopeptidase, S33 88 218 3.6E-10 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 HVS_RS01285 799b9a4f2f21dbe5627236197338b9d6 654 Gene3D G3DSA:1.20.5.50 30 140 0.12 T 29-03-2018 HVS_RS01285 799b9a4f2f21dbe5627236197338b9d6 654 Pfam PF01496 V-type ATPase 116kDa subunit family 553 644 2.9E-11 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01285 799b9a4f2f21dbe5627236197338b9d6 654 Pfam PF01496 V-type ATPase 116kDa subunit family 142 412 1.7E-14 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01285 799b9a4f2f21dbe5627236197338b9d6 654 Gene3D G3DSA:1.20.5.730 219 273 0.025 T 29-03-2018 HVS_RS10360 54caaecfd08d9d17886d73e53d1fda2b 247 SUPERFAMILY SSF52317 17 198 1.72E-21 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS10360 54caaecfd08d9d17886d73e53d1fda2b 247 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 5 205 7.6E-41 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 HVS_RS10360 54caaecfd08d9d17886d73e53d1fda2b 247 Gene3D G3DSA:3.40.50.880 13 239 7.2E-14 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like HVS_RS09975 c7997df0a0573a046c90089d8d4cbaf2 394 Gene3D G3DSA:3.30.70.60 83 208 2.6E-5 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HVS_RS04640 b804ff69fc58ceca4aae23c770e30654 182 Gene3D G3DSA:2.60.40.1240 56 178 5.9E-24 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain HVS_RS04640 b804ff69fc58ceca4aae23c770e30654 182 Pfam PF11611 Domain of unknown function (DUF4352) 58 174 9.4E-28 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 HVS_RS07645 0e66849e6ff107aeabcd0c44f8de8e91 178 SUPERFAMILY SSF53323 2 176 8.5E-39 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HVS_RS07645 0e66849e6ff107aeabcd0c44f8de8e91 178 Gene3D G3DSA:3.40.920.10 1 178 2.2E-39 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS07645 0e66849e6ff107aeabcd0c44f8de8e91 178 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 174 4.8E-27 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS07480 4cb7455c0ac52142f025eabe3446b962 400 Gene3D G3DSA:3.40.50.410 201 391 9.7E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS07480 4cb7455c0ac52142f025eabe3446b962 400 Pfam PF01882 Protein of unknown function DUF58 192 274 8.5E-17 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS06315 84bde78e145183d46f7712b83d9ef395 408 Pfam PF01136 Peptidase family U32 76 308 2.7E-100 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HVS_RS06315 84bde78e145183d46f7712b83d9ef395 408 Gene3D G3DSA:3.20.20.70 5 172 3.0E-6 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS06315 84bde78e145183d46f7712b83d9ef395 408 ProSitePatterns PS01276 Peptidase family U32 signature. 163 181 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 HVS_RS06315 84bde78e145183d46f7712b83d9ef395 408 Pfam PF16325 Peptidase family U32 C-terminal domain 322 404 9.5E-26 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal HVS_RS02470 f25eaafaf5bf2240b9f0e28990595998 421 Pfam PF01098 Cell cycle protein 65 410 1.5E-74 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 SUPERFAMILY SSF51161 4 170 6.79E-55 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 166 2.6E-73 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 Gene3D G3DSA:1.10.3130.10 1 61 1.3E-24 T 29-03-2018 HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.0E-4 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 Gene3D G3DSA:2.160.10.10 62 231 2.6E-37 T 29-03-2018 HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 PIRSF PIRSF000441 1 245 1.0E-83 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 2.9E-8 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS15720 1e013d11984bb30a750402e3f89f40a1 246 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 3.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS03325 8807bd6ada51eb1f4c4255f549416042 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.1E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS03325 8807bd6ada51eb1f4c4255f549416042 86 SMART SM00966 8 51 1.7E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS03325 8807bd6ada51eb1f4c4255f549416042 86 Gene3D G3DSA:2.10.260.10 1 48 1.0E-18 T 29-03-2018 HVS_RS03325 8807bd6ada51eb1f4c4255f549416042 86 SUPERFAMILY SSF89447 2 51 1.31E-15 T 29-03-2018 HVS_RS03325 8807bd6ada51eb1f4c4255f549416042 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 1.4E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS05000 a95c9839572b85ba0eadb93efe4881d7 224 Pfam PF03787 RAMP superfamily 7 198 1.7E-8 T 29-03-2018 IPR005537 CRISPR type III-associated RAMP protein HVS_RS13060 1cc76886120f0c79584a59403861eb5f 222 Pfam PF01381 Helix-turn-helix 9 61 9.9E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS13060 1cc76886120f0c79584a59403861eb5f 222 Gene3D G3DSA:1.10.3100.10 1 114 1.0E-21 T 29-03-2018 IPR027910 YdiL-like domain HVS_RS13060 1cc76886120f0c79584a59403861eb5f 222 SMART SM00530 6 61 1.1E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS13060 1cc76886120f0c79584a59403861eb5f 222 SUPERFAMILY SSF47413 1 64 9.73E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS12810 90f256ec4e403345b48b1bbdd031d51e 103 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 69 88 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS12810 90f256ec4e403345b48b1bbdd031d51e 103 Gene3D G3DSA:1.10.1330.10 32 100 4.2E-5 T 29-03-2018 HVS_RS12810 90f256ec4e403345b48b1bbdd031d51e 103 ProSitePatterns PS00018 EF-hand calcium-binding domain. 69 81 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS12810 90f256ec4e403345b48b1bbdd031d51e 103 SUPERFAMILY SSF63446 31 98 1.96E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS12810 90f256ec4e403345b48b1bbdd031d51e 103 Pfam PF00404 Dockerin type I repeat 69 89 1.8E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS02955 86f0135319fbcc2fb0d46e4c00ac34d6 576 Pfam PF01609 Transposase DDE domain 230 500 1.5E-11 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HVS_RS02955 86f0135319fbcc2fb0d46e4c00ac34d6 576 Gene3D G3DSA:3.90.350.10 171 484 4.5E-40 T 29-03-2018 IPR014736 Transposase, Tn5-like, core HVS_RS02955 86f0135319fbcc2fb0d46e4c00ac34d6 576 SUPERFAMILY SSF53098 439 512 9.86E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13355 5f114ac5b357130accfb076528e804af 422 Pfam PF01610 Transposase 292 412 1.5E-14 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS13355 5f114ac5b357130accfb076528e804af 422 Pfam PF01610 Transposase 4 110 5.2E-8 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS13355 5f114ac5b357130accfb076528e804af 422 Gene3D G3DSA:1.10.10.60 148 207 5.2E-9 T 29-03-2018 HVS_RS14120 6be889e16bbd7f30b0703b4b674f91db 552 Pfam PF13584 Oxygen tolerance 33 475 4.6E-86 T 29-03-2018 IPR025738 Aerotolerance-related protein BatD HVS_RS15325 62186507a1276a68719d280f4359318c 244 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 236 2.6E-30 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase HVS_RS01290 d64ecb50dd6a23dcf59884961ac17b59 108 Pfam PF00430 ATP synthase B/B' CF(0) 8 92 7.8E-7 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HVS_RS01290 d64ecb50dd6a23dcf59884961ac17b59 108 SUPERFAMILY SSF81573 23 75 9.42E-5 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS01290 d64ecb50dd6a23dcf59884961ac17b59 108 Gene3D G3DSA:1.20.5.620 6 78 9.7E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain HVS_RS15490 1ad5f08ecae4d420d2d96436aa2db668 262 Gene3D G3DSA:3.30.360.40 192 262 1.9E-24 T 29-03-2018 HVS_RS15490 1ad5f08ecae4d420d2d96436aa2db668 262 Pfam PF08680 TATA-box binding 64 262 4.4E-46 T 29-03-2018 IPR014794 TATA-box binding HVS_RS15490 1ad5f08ecae4d420d2d96436aa2db668 262 SUPERFAMILY SSF143842 73 259 7.19E-39 T 29-03-2018 IPR014794 TATA-box binding HVS_RS09550 234b9e6d81188241e6f82c0fa43416b1 428 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 10 418 8.0E-66 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HVS_RS09550 234b9e6d81188241e6f82c0fa43416b1 428 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 251 416 1.2E-29 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 HVS_RS14955 be666b4eb2f0359c33292ceea835d0a5 159 SMART SM01058 1 111 6.8E-36 T 29-03-2018 IPR003711 CarD-like/TRCF domain HVS_RS14955 be666b4eb2f0359c33292ceea835d0a5 159 SUPERFAMILY SSF141259 2 66 3.27E-14 T 29-03-2018 IPR003711 CarD-like/TRCF domain HVS_RS14955 be666b4eb2f0359c33292ceea835d0a5 159 Pfam PF02559 CarD-like/TRCF domain 2 109 1.4E-21 T 29-03-2018 IPR003711 CarD-like/TRCF domain HVS_RS07980 a2e7d23adcaa765d33a5e2e00da446cb 177 SUPERFAMILY SSF52467 25 152 8.18E-11 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS07980 a2e7d23adcaa765d33a5e2e00da446cb 177 Gene3D G3DSA:3.40.50.1220 22 164 9.8E-43 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS07980 a2e7d23adcaa765d33a5e2e00da446cb 177 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 22 163 2.1E-31 T 29-03-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 HVS_RS05280 180c59a2d6818276a78dbffd4c0b3f33 114 SMART SM00637 11 111 3.4E-23 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 HVS_RS05280 180c59a2d6818276a78dbffd4c0b3f33 114 Gene3D G3DSA:2.60.40.290 1 111 8.0E-28 T 29-03-2018 HVS_RS05280 180c59a2d6818276a78dbffd4c0b3f33 114 Pfam PF00553 Cellulose binding domain 11 111 4.5E-25 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 HVS_RS05280 180c59a2d6818276a78dbffd4c0b3f33 114 SUPERFAMILY SSF49384 4 113 1.19E-26 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS14410 7a74a1ddf2b32306cb503ddbe8f38532 269 SUPERFAMILY SSF144091 18 185 7.98E-16 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS14410 7a74a1ddf2b32306cb503ddbe8f38532 269 Gene3D G3DSA:1.20.1540.10 15 195 3.9E-19 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HVS_RS14410 7a74a1ddf2b32306cb503ddbe8f38532 269 Pfam PF04511 Der1-like family 59 225 1.1E-7 T 29-03-2018 HVS_RS00830 bad18b0df3ffcb38858af7d235d3e60b 729 Pfam PF00665 Integrase core domain 304 420 3.4E-11 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS00830 bad18b0df3ffcb38858af7d235d3e60b 729 SUPERFAMILY SSF53098 304 470 9.29E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS00830 bad18b0df3ffcb38858af7d235d3e60b 729 Pfam PF09299 Mu transposase, C-terminal 514 574 6.8E-6 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal HVS_RS00830 bad18b0df3ffcb38858af7d235d3e60b 729 Gene3D G3DSA:3.30.420.10 283 510 1.1E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS00830 bad18b0df3ffcb38858af7d235d3e60b 729 Gene3D G3DSA:2.30.30.130 511 587 4.5E-5 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 228 107.429 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 PIRSF PIRSF000386 1 228 4.4E-105 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 1.4E-69 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 Gene3D G3DSA:1.10.1270.20 173 228 7.7E-30 T 29-03-2018 HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 Gene3D G3DSA:3.40.1280.10 1 172 2.1E-76 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 226 3.7E-98 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HVS_RS08360 537a507e559857d517ab3fbe9afe8f30 228 SUPERFAMILY SSF75217 1 226 2.16E-99 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases HVS_RS09190 a719e80e60444dc4460d7a9a69902ae2 309 Gene3D G3DSA:1.10.10.630 203 287 0.0017 T 29-03-2018 IPR034829 DnaD-like domain HVS_RS09190 a719e80e60444dc4460d7a9a69902ae2 309 SUPERFAMILY SSF88659 8 47 4.11E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HVS_RS09190 a719e80e60444dc4460d7a9a69902ae2 309 Gene3D G3DSA:1.10.10.60 2 49 6.4E-9 T 29-03-2018 HVS_RS09570 9820896c0d990692f6ddb0887c844eb6 267 Gene3D G3DSA:2.40.40.10 49 259 1.0E-25 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HVS_RS09570 9820896c0d990692f6ddb0887c844eb6 267 Pfam PF06725 3D domain 195 255 3.5E-11 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 HVS_RS09570 9820896c0d990692f6ddb0887c844eb6 267 SUPERFAMILY SSF50685 186 234 4.53E-11 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain HVS_RS02670 1a665f23e5358e6a4c25ea96e9cf59e0 409 Gene3D G3DSA:3.90.1150.10 276 409 5.8E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS02670 1a665f23e5358e6a4c25ea96e9cf59e0 409 Gene3D G3DSA:3.40.640.10 1 274 9.3E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HVS_RS02670 1a665f23e5358e6a4c25ea96e9cf59e0 409 PIRSF PIRSF001434 1 409 2.5E-126 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HVS_RS02670 1a665f23e5358e6a4c25ea96e9cf59e0 409 SUPERFAMILY SSF53383 1 407 2.26E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase HVS_RS02670 1a665f23e5358e6a4c25ea96e9cf59e0 409 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 407 2.0E-124 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 HVS_RS05665 145105f72cf13b0d40b20643782b5f58 277 SUPERFAMILY SSF55383 56 139 9.94E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05665 145105f72cf13b0d40b20643782b5f58 277 Pfam PF07833 Copper amine oxidase N-terminal domain 54 145 1.0E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05665 145105f72cf13b0d40b20643782b5f58 277 Gene3D G3DSA:3.30.457.10 7 65 3.1E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05665 145105f72cf13b0d40b20643782b5f58 277 Gene3D G3DSA:3.30.457.10 66 127 2.9E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05665 145105f72cf13b0d40b20643782b5f58 277 Gene3D G3DSA:3.30.457.10 128 195 1.1E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS15070 7561cd37fb4412ef2bcdf1a3622b2232 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.187 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15070 7561cd37fb4412ef2bcdf1a3622b2232 132 Gene3D G3DSA:3.30.1370.30 1 67 5.0E-27 T 29-03-2018 HVS_RS15070 7561cd37fb4412ef2bcdf1a3622b2232 132 Pfam PF00410 Ribosomal protein S8 5 132 1.1E-53 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15070 7561cd37fb4412ef2bcdf1a3622b2232 132 Gene3D G3DSA:3.30.1490.10 76 131 9.2E-23 T 29-03-2018 HVS_RS15070 7561cd37fb4412ef2bcdf1a3622b2232 132 SUPERFAMILY SSF56047 4 132 5.23E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS15070 7561cd37fb4412ef2bcdf1a3622b2232 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 HVS_RS08710 5c2c12bbd9a2e3fbcd5a10d0a80f1284 88 Pfam PF10719 Late competence development protein ComFB 5 85 7.4E-26 T 29-03-2018 IPR019657 Late competence development protein ComFB HVS_RS10510 26da52a9333d0067a713b3a3ed625b3e 318 Pfam PF01368 DHH family 17 156 5.8E-13 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS10510 26da52a9333d0067a713b3a3ed625b3e 318 Gene3D G3DSA:3.90.1640.10 1 197 9.8E-45 T 29-03-2018 HVS_RS10510 26da52a9333d0067a713b3a3ed625b3e 318 SUPERFAMILY SSF64182 15 311 3.14E-68 T 29-03-2018 HVS_RS10510 26da52a9333d0067a713b3a3ed625b3e 318 Pfam PF02272 DHHA1 domain 232 312 2.0E-11 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 HVS_RS01655 ff7a9a909df59ed861012ec62745de0a 225 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 10 198 6.8E-75 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 HVS_RS01655 ff7a9a909df59ed861012ec62745de0a 225 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 191 3.9E-68 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HVS_RS01655 ff7a9a909df59ed861012ec62745de0a 225 PIRSF PIRSF006102 4 209 5.3E-70 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HVS_RS01655 ff7a9a909df59ed861012ec62745de0a 225 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 4 201 26.17 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 HVS_RS12645 6941cc995322629d86cca3f5893e13c6 153 PIRSF PIRSF010607 1 153 8.7E-55 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 HVS_RS12645 6941cc995322629d86cca3f5893e13c6 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 149 2.6E-54 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 HVS_RS02800 1f7089777c97e4542e41cfc11315682c 193 Pfam PF08747 Domain of unknown function (DUF1788) 67 190 9.5E-46 T 29-03-2018 IPR014858 Protein of unknown function DUF1788 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 84 90 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 SUPERFAMILY SSF53335 136 361 3.8E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 SUPERFAMILY SSF53335 58 100 3.8E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 Gene3D G3DSA:3.40.50.150 59 366 1.1E-53 T 29-03-2018 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 Pfam PF01555 DNA methylase 81 347 1.4E-42 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 81 93 5.1E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 314 328 5.1E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 148 167 5.1E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 HVS_RS13770 faf58921e877afaae917ae24dc8a75d5 647 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 291 313 5.1E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 76 304 4.6E-37 T 29-03-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 SUPERFAMILY SSF53920 43 359 5.75E-57 T 29-03-2018 IPR009016 Iron hydrogenase HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 Gene3D G3DSA:3.40.50.1780 144 260 2.7E-11 T 29-03-2018 HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 Gene3D G3DSA:3.40.50.1780 45 143 1.9E-18 T 29-03-2018 HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 Pfam PF04060 Putative Fe-S cluster 376 408 1.3E-12 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 15 26 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 Pfam PF13237 4Fe-4S dicluster domain 8 55 5.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 Gene3D G3DSA:3.30.70.20 5 44 1.7E-13 T 29-03-2018 HVS_RS02730 feb742840abeaf26d7da38389321dde1 426 SUPERFAMILY SSF54862 10 65 3.43E-17 T 29-03-2018 HVS_RS10170 4c71c89692bbf996cd62bb339841ee88 262 Pfam PF01311 Bacterial export proteins, family 1 13 246 5.7E-71 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HVS_RS10170 4c71c89692bbf996cd62bb339841ee88 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 14 250 2.6E-64 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 HVS_RS10170 4c71c89692bbf996cd62bb339841ee88 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.1E-26 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HVS_RS10170 4c71c89692bbf996cd62bb339841ee88 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.1E-26 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HVS_RS10170 4c71c89692bbf996cd62bb339841ee88 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 1.1E-26 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HVS_RS10170 4c71c89692bbf996cd62bb339841ee88 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.1E-26 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 HVS_RS14970 0812604cf0040c596ca09bf45a13525a 269 Pfam PF02361 Cobalt transport protein 14 234 6.4E-43 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 SUPERFAMILY SSF47384 492 527 1.06E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 SUPERFAMILY SSF55874 653 802 2.49E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 788 801 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 752 762 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 765 783 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 734 748 2.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 SMART SM00387 697 804 3.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 Gene3D G3DSA:1.10.287.620 396 533 2.6E-4 T 29-03-2018 HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 699 802 2.9E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02405 70c88806acbc2787f3fc210e90f66915 812 Gene3D G3DSA:3.30.565.10 655 804 1.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 294 54.887 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 86 2.0E-17 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 Pfam PF00589 Phage integrase family 111 280 1.8E-49 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 SUPERFAMILY SSF56349 3 286 1.56E-60 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 294 8.2E-114 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 Gene3D G3DSA:1.10.150.130 1 109 8.2E-24 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal HVS_RS09520 7a7f16fecfec9440878dc334d10bc671 294 Gene3D G3DSA:1.10.443.10 110 288 1.7E-47 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS01420 51bf5d8e99713c69cfd2c43c56a9b1c8 617 Pfam PF01973 Protein of unknown function DUF115 205 373 5.1E-45 T 29-03-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like HVS_RS01420 51bf5d8e99713c69cfd2c43c56a9b1c8 617 Gene3D G3DSA:3.90.1480.10 208 537 2.0E-44 T 29-03-2018 HVS_RS05325 ac90e6e06f76abf7835e243958788aa9 111 Pfam PF12732 YtxH-like protein 28 98 8.4E-18 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH HVS_RS02200 918716d7a2be19f7679d605d7c905159 392 Pfam PF16927 N-terminal 7TM region of histidine kinase 24 239 1.2E-13 T 29-03-2018 IPR031621 Histidine kinase, N-terminal 7TM region HVS_RS14945 08c2d010c0f162a8ef7df998f6658e13 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 228 1.1E-73 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HVS_RS14945 08c2d010c0f162a8ef7df998f6658e13 233 Gene3D G3DSA:3.90.550.10 1 233 3.6E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS14945 08c2d010c0f162a8ef7df998f6658e13 233 SUPERFAMILY SSF53448 10 229 8.35E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS14945 08c2d010c0f162a8ef7df998f6658e13 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 107 114 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HVS_RS14945 08c2d010c0f162a8ef7df998f6658e13 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 10 229 39.774 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HVS_RS14945 08c2d010c0f162a8ef7df998f6658e13 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 230 8.1E-64 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 Pfam PF04397 LytTr DNA-binding domain 268 365 6.3E-23 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 SUPERFAMILY SSF52172 6 133 1.85E-23 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 SMART SM00850 267 366 1.2E-26 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 Gene3D G3DSA:2.20.25.10 328 366 4.8E-6 T 29-03-2018 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 Gene3D G3DSA:3.40.50.2300 4 258 9.3E-26 T 29-03-2018 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 Gene3D G3DSA:2.40.50.40 259 327 4.2E-19 T 29-03-2018 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 Pfam PF00072 Response regulator receiver domain 6 124 1.6E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02385 9606ccf80721483e8869db4c1a265243 370 SMART SM00448 4 124 7.0E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS15920 7331b3ccaef9d865696f791dfabb6202 68 SUPERFAMILY SSF143011 2 63 1.96E-13 T 29-03-2018 IPR035095 Toxin RelE-like domain HVS_RS15920 7331b3ccaef9d865696f791dfabb6202 68 Gene3D G3DSA:3.30.2310.20 2 66 6.2E-11 T 29-03-2018 HVS_RS15920 7331b3ccaef9d865696f791dfabb6202 68 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 20 65 1.1E-5 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 SUPERFAMILY SSF53335 8 279 8.94E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 Gene3D G3DSA:3.40.50.150 1 217 3.5E-62 T 29-03-2018 HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 13 278 54.005 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 Gene3D G3DSA:1.10.8.100 218 279 1.2E-19 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 270 9.7E-65 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 14 276 1.3E-85 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 45 72 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HVS_RS14575 fb23740c37c9e2e73904e68a21019a5b 282 SMART SM00650 29 203 8.0E-80 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 HVS_RS08525 c975725ff223e39d918a05ae13ad4a4e 216 Gene3D G3DSA:3.40.50.1000 73 216 9.1E-30 T 29-03-2018 IPR023214 HAD-like domain HVS_RS08525 c975725ff223e39d918a05ae13ad4a4e 216 Gene3D G3DSA:3.40.50.1000 1 28 0.13 T 29-03-2018 IPR023214 HAD-like domain HVS_RS08525 c975725ff223e39d918a05ae13ad4a4e 216 Gene3D G3DSA:1.10.150.240 29 72 5.2E-20 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 HVS_RS08525 c975725ff223e39d918a05ae13ad4a4e 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 3.4E-30 T 29-03-2018 IPR023214 HAD-like domain HVS_RS08525 c975725ff223e39d918a05ae13ad4a4e 216 SUPERFAMILY SSF56784 1 214 3.25E-55 T 29-03-2018 IPR023214 HAD-like domain HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 Gene3D G3DSA:1.10.1200.80 246 324 2.7E-21 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 SUPERFAMILY SSF51395 10 313 3.48E-92 T 29-03-2018 HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 Pfam PF01207 Dihydrouridine synthase (Dus) 14 308 6.4E-101 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 PIRSF PIRSF006621 1 323 3.8E-108 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 315 2.6E-122 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 HVS_RS14505 5b1ed2e456ed0f7fba390a51216b5b92 327 Gene3D G3DSA:3.20.20.70 8 242 2.1E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS12280 4b8d0ba5a296a2de1eef11d69e475671 289 SUPERFAMILY SSF52540 4 216 1.01E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS12280 4b8d0ba5a296a2de1eef11d69e475671 289 SMART SM00382 30 211 4.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12280 4b8d0ba5a296a2de1eef11d69e475671 289 Pfam PF00005 ABC transporter 32 163 6.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS12280 4b8d0ba5a296a2de1eef11d69e475671 289 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS12280 4b8d0ba5a296a2de1eef11d69e475671 289 Gene3D G3DSA:3.40.50.300 5 275 1.4E-55 T 29-03-2018 HVS_RS05545 ab06be8ec1252d665cc74a30794aa307 418 Gene3D G3DSA:1.20.120.20 37 400 8.0E-5 T 29-03-2018 HVS_RS02170 b93ae5c87c64a83248512a97d517cbfa 396 Gene3D G3DSA:1.10.8.60 317 382 1.1E-13 T 29-03-2018 HVS_RS02170 b93ae5c87c64a83248512a97d517cbfa 396 Gene3D G3DSA:3.40.50.300 127 316 1.7E-47 T 29-03-2018 HVS_RS02170 b93ae5c87c64a83248512a97d517cbfa 396 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 177 309 2.5E-35 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 HVS_RS02170 b93ae5c87c64a83248512a97d517cbfa 396 ProSitePatterns PS00674 AAA-protein family signature. 280 298 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 HVS_RS02170 b93ae5c87c64a83248512a97d517cbfa 396 SMART SM00382 173 312 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS02170 b93ae5c87c64a83248512a97d517cbfa 396 SUPERFAMILY SSF52540 134 380 1.49E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08955 6bd675c581215d3cfb1025b0a892f662 102 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 16 96 5.5E-25 T 29-03-2018 IPR003849 Preprotein translocase YajC HVS_RS08955 6bd675c581215d3cfb1025b0a892f662 102 PRINTS PR01853 Bacterial YajC preprotein translocase signature 54 72 1.5E-11 T 29-03-2018 IPR003849 Preprotein translocase YajC HVS_RS08955 6bd675c581215d3cfb1025b0a892f662 102 PRINTS PR01853 Bacterial YajC preprotein translocase signature 16 36 1.5E-11 T 29-03-2018 IPR003849 Preprotein translocase YajC HVS_RS08955 6bd675c581215d3cfb1025b0a892f662 102 Pfam PF02699 Preprotein translocase subunit 20 94 2.0E-27 T 29-03-2018 IPR003849 Preprotein translocase YajC HVS_RS08955 6bd675c581215d3cfb1025b0a892f662 102 SMART SM01323 14 97 4.2E-33 T 29-03-2018 IPR003849 Preprotein translocase YajC HVS_RS08870 5370d0a6810b08c5c83e5727c1952b34 226 Gene3D G3DSA:3.40.50.1240 1 213 2.4E-57 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS08870 5370d0a6810b08c5c83e5727c1952b34 226 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 4.8E-60 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HVS_RS08870 5370d0a6810b08c5c83e5727c1952b34 226 SUPERFAMILY SSF53254 1 205 9.03E-62 T 29-03-2018 IPR029033 Histidine phosphatase superfamily HVS_RS08870 5370d0a6810b08c5c83e5727c1952b34 226 SMART SM00855 4 158 1.1E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 HVS_RS08870 5370d0a6810b08c5c83e5727c1952b34 226 PIRSF PIRSF000709 2 196 1.6E-18 T 29-03-2018 HVS_RS00315 664e1df70133b2a59d5290fde64977fc 292 Pfam PF00395 S-layer homology domain 41 82 4.8E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS00315 664e1df70133b2a59d5290fde64977fc 292 Pfam PF00395 S-layer homology domain 104 146 9.6E-15 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS00315 664e1df70133b2a59d5290fde64977fc 292 Pfam PF00395 S-layer homology domain 167 208 2.4E-11 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS03165 9fde362f249add25b52030f9e8ba62e5 157 SUPERFAMILY SSF52540 23 135 5.36E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03165 9fde362f249add25b52030f9e8ba62e5 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 126 7.5E-38 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HVS_RS03165 9fde362f249add25b52030f9e8ba62e5 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 8 126 1.4E-38 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HVS_RS03165 9fde362f249add25b52030f9e8ba62e5 157 Gene3D G3DSA:3.40.50.300 1 154 9.2E-46 T 29-03-2018 HVS_RS06720 4ff72fc59f996dfd9c89ff79bc702a9b 349 Gene3D G3DSA:1.10.10.60 265 341 0.13 T 29-03-2018 HVS_RS06720 4ff72fc59f996dfd9c89ff79bc702a9b 349 Pfam PF04754 Putative transposase, YhgA-like 9 211 3.4E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 SMART SM00418 5 79 2.1E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 6.5E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 6.5E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 6.5E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 Gene3D G3DSA:1.10.10.10 1 81 2.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 SUPERFAMILY SSF46785 2 88 5.81E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02855 21f28cf02dda8ac51ccddb7489dfd244 122 Pfam PF01022 Bacterial regulatory protein, arsR family 12 56 2.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HVS_RS00185 87ac5aaf13920a43ef49e885dbc02c27 247 Pfam PF12804 MobA-like NTP transferase domain 5 130 1.0E-18 T 29-03-2018 IPR025877 MobA-like NTP transferase HVS_RS00185 87ac5aaf13920a43ef49e885dbc02c27 247 Gene3D G3DSA:3.90.550.10 2 240 5.3E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS00185 87ac5aaf13920a43ef49e885dbc02c27 247 SUPERFAMILY SSF53448 3 237 4.73E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS01040 e49cd30d103a507deedf0b941a80b1d5 406 ProSitePatterns PS01007 Transposases, Mutator family, signature. 235 259 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HVS_RS01040 e49cd30d103a507deedf0b941a80b1d5 406 Gene3D G3DSA:1.10.10.10 24 160 7.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS01040 e49cd30d103a507deedf0b941a80b1d5 406 Pfam PF00872 Transposase, Mutator family 7 381 2.7E-120 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HVS_RS08875 27736c1a49d16e943a95b76085fd22d9 148 Gene3D G3DSA:1.20.5.320 12 59 0.0018 T 29-03-2018 HVS_RS08875 27736c1a49d16e943a95b76085fd22d9 148 Gene3D G3DSA:1.20.5.50 60 145 0.006 T 29-03-2018 HVS_RS08875 27736c1a49d16e943a95b76085fd22d9 148 SUPERFAMILY SSF116842 76 132 4.18E-5 T 29-03-2018 HVS_RS04480 07a9f9b90bde02e8775ada81d360fbc3 90 Gene3D G3DSA:1.10.10.10 9 85 1.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 PRINTS PR00063 Ribosomal protein L27 signature 12 36 5.7E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 PRINTS PR00063 Ribosomal protein L27 signature 62 86 5.7E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 PRINTS PR00063 Ribosomal protein L27 signature 37 61 5.7E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 Pfam PF01016 Ribosomal L27 protein 10 89 7.2E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 1.4E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 28.382 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 SUPERFAMILY SSF110324 10 90 4.19E-33 T 29-03-2018 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 Gene3D G3DSA:2.40.50.100 28 92 9.6E-32 T 29-03-2018 HVS_RS11555 2c8370140a43078c79bcd3ca1fba6216 92 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 2.0E-15 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 HVS_RS10225 1b58c067ed057bfae5c8ed95a7594796 293 Pfam PF13861 FlgD Tudor-like domain 83 135 7.0E-8 T 29-03-2018 IPR025963 FlgD Tudor-like domain HVS_RS10225 1b58c067ed057bfae5c8ed95a7594796 293 Pfam PF03963 Flagellar hook capping protein - N-terminal region 13 80 2.4E-23 T 29-03-2018 IPR005648 Flagellar hook capping protein HVS_RS14515 e6c5af0a58f8af3bea16d5f6b61ff9fa 131 Gene3D G3DSA:3.90.79.10 2 121 0.0017 T 29-03-2018 HVS_RS14515 e6c5af0a58f8af3bea16d5f6b61ff9fa 131 SUPERFAMILY SSF55811 3 91 7.41E-7 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 HVS_RS05600 ec7bc55aa05af751d72221957c214a8a 480 Gene3D G3DSA:3.30.450.90 90 196 2.3E-24 T 29-03-2018 HVS_RS05600 ec7bc55aa05af751d72221957c214a8a 480 SUPERFAMILY SSF52540 80 387 2.0E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05600 ec7bc55aa05af751d72221957c214a8a 480 Gene3D G3DSA:3.40.50.300 197 476 1.3E-9 T 29-03-2018 HVS_RS05600 ec7bc55aa05af751d72221957c214a8a 480 Pfam PF00437 Type II/IV secretion system protein 97 359 2.0E-35 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HVS_RS02425 1388639ac41c36186738827eba839455 454 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 148 269 3.4E-7 T 29-03-2018 HVS_RS12565 6c8e2611daa2d96130c504df4e6ea9b7 399 Pfam PF07690 Major Facilitator Superfamily 11 248 3.4E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HVS_RS12565 6c8e2611daa2d96130c504df4e6ea9b7 399 SUPERFAMILY SSF103473 5 393 4.71E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain HVS_RS12565 6c8e2611daa2d96130c504df4e6ea9b7 399 Gene3D G3DSA:1.20.1250.20 2 190 1.7E-17 T 29-03-2018 HVS_RS12565 6c8e2611daa2d96130c504df4e6ea9b7 399 Gene3D G3DSA:1.20.1250.20 202 398 1.9E-17 T 29-03-2018 HVS_RS13925 8e2cfd5f1b4f464fe6cd5f9df3b27909 435 Gene3D G3DSA:3.40.190.10 229 389 0.0068 T 29-03-2018 HVS_RS13925 8e2cfd5f1b4f464fe6cd5f9df3b27909 435 Pfam PF13416 Bacterial extracellular solute-binding protein 68 355 5.4E-20 T 29-03-2018 HVS_RS13925 8e2cfd5f1b4f464fe6cd5f9df3b27909 435 Gene3D G3DSA:3.40.190.10 40 217 8.6E-26 T 29-03-2018 HVS_RS13925 8e2cfd5f1b4f464fe6cd5f9df3b27909 435 SUPERFAMILY SSF53850 53 430 1.04E-38 T 29-03-2018 HVS_RS05550 69ecafa0cb00dce0aa475547d3cad152 262 Gene3D G3DSA:3.60.40.10 6 256 6.4E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS05550 69ecafa0cb00dce0aa475547d3cad152 262 SUPERFAMILY SSF81606 5 255 2.22E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS05550 69ecafa0cb00dce0aa475547d3cad152 262 SMART SM00331 7 256 4.7E-14 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS05550 69ecafa0cb00dce0aa475547d3cad152 262 Pfam PF13672 Protein phosphatase 2C 19 237 7.9E-8 T 29-03-2018 HVS_RS05550 69ecafa0cb00dce0aa475547d3cad152 262 SMART SM00332 1 254 5.5E-17 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 HVS_RS06730 c32aafc785ef5a06b19f5d597ba7b676 328 Gene3D G3DSA:3.30.457.10 62 122 1.0E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06730 c32aafc785ef5a06b19f5d597ba7b676 328 Gene3D G3DSA:3.30.457.10 9 61 5.0E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06730 c32aafc785ef5a06b19f5d597ba7b676 328 Gene3D G3DSA:3.30.457.10 123 280 8.4E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06730 c32aafc785ef5a06b19f5d597ba7b676 328 Pfam PF07833 Copper amine oxidase N-terminal domain 49 141 2.1E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06730 c32aafc785ef5a06b19f5d597ba7b676 328 SUPERFAMILY SSF55383 52 135 4.05E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07395 54be72da805c74831a5ad5483302dc8a 397 PIRSF PIRSF029895 2 397 8.8E-108 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD HVS_RS07395 54be72da805c74831a5ad5483302dc8a 397 Gene3D G3DSA:2.40.50.100 191 360 0.0014 T 29-03-2018 HVS_RS07395 54be72da805c74831a5ad5483302dc8a 397 Pfam PF06898 Putative stage IV sporulation protein YqfD 8 388 1.6E-131 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD HVS_RS07395 54be72da805c74831a5ad5483302dc8a 397 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 6 389 1.9E-100 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD HVS_RS08500 4581e1bfd442e6c24a7992ee574dd1d0 218 Pfam PF13346 ABC-2 family transporter protein 4 214 8.4E-35 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like HVS_RS04575 764d3d46f9561b975631d1af07022aa6 482 Pfam PF04986 Putative transposase 167 336 2.1E-24 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS04575 764d3d46f9561b975631d1af07022aa6 482 Pfam PF14319 Transposase zinc-binding domain 32 140 9.1E-28 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS13705 9766eba2918b61764aea681ba4fc8a66 137 Gene3D G3DSA:3.10.420.10 2 136 2.3E-24 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 HVS_RS13705 9766eba2918b61764aea681ba4fc8a66 137 Pfam PF02556 Preprotein translocase subunit SecB 23 134 5.2E-12 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 HVS_RS13705 9766eba2918b61764aea681ba4fc8a66 137 SUPERFAMILY SSF54611 14 135 5.45E-18 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 HVS_RS09910 47d201949ac2cc7b9e3ca848c1fa25ee 71 Pfam PF13396 Phospholipase_D-nuclease N-terminal 24 65 1.3E-10 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal HVS_RS16000 fda8a51931fe6b438df445efdbba396a 388 SUPERFAMILY SSF53474 151 319 3.14E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS16000 fda8a51931fe6b438df445efdbba396a 388 Gene3D G3DSA:2.60.40.10 42 150 5.2E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS16000 fda8a51931fe6b438df445efdbba396a 388 Gene3D G3DSA:3.40.50.1820 151 383 2.0E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS14140 49e83816cabced6595a2f0af928e8d9c 80 Pfam PF02001 Protein of unknown function DUF134 28 64 4.4E-8 T 29-03-2018 IPR002852 Uncharacterised protein family UPF0251 HVS_RS00110 7d1cc9870cd75d3785f538dba1f25c3d 192 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 5 190 2.6E-69 T 29-03-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 HVS_RS00110 7d1cc9870cd75d3785f538dba1f25c3d 192 SUPERFAMILY SSF53323 4 190 5.36E-53 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 HVS_RS00110 7d1cc9870cd75d3785f538dba1f25c3d 192 Gene3D G3DSA:3.40.920.10 2 191 6.8E-49 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS00110 7d1cc9870cd75d3785f538dba1f25c3d 192 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 186 1.4E-40 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 HVS_RS02555 281a181e58aea0ee267fb0b5b9a1ffeb 490 Gene3D G3DSA:1.10.287.950 236 337 2.1E-4 T 29-03-2018 HVS_RS02555 281a181e58aea0ee267fb0b5b9a1ffeb 490 Gene3D G3DSA:1.20.5.1230 338 489 2.5E-4 T 29-03-2018 HVS_RS06300 a9862107a78482374b5000706fbea2f7 63 Gene3D G3DSA:3.40.190.10 3 63 8.3E-5 T 29-03-2018 HVS_RS06300 a9862107a78482374b5000706fbea2f7 63 SUPERFAMILY SSF161219 15 57 4.58E-5 T 29-03-2018 HVS_RS08315 4d74e179f38a145aafcc890cc1aa11eb 175 Pfam PF13238 AAA domain 10 135 2.7E-9 T 29-03-2018 HVS_RS08315 4d74e179f38a145aafcc890cc1aa11eb 175 Gene3D G3DSA:3.40.50.300 5 173 9.4E-20 T 29-03-2018 HVS_RS08315 4d74e179f38a145aafcc890cc1aa11eb 175 SUPERFAMILY SSF52540 7 166 9.24E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02815 e55b776c2ec22fe85a2024fe78525bec 851 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 22 840 1.3E-219 T 29-03-2018 IPR014060 Conserved hypothetical protein CHP02687 HVS_RS02815 e55b776c2ec22fe85a2024fe78525bec 851 Gene3D G3DSA:3.40.720.10 127 651 1.8E-4 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HVS_RS02815 e55b776c2ec22fe85a2024fe78525bec 851 Pfam PF08665 PglZ domain 462 637 1.2E-52 T 29-03-2018 IPR013973 PglZ domain HVS_RS02815 e55b776c2ec22fe85a2024fe78525bec 851 SUPERFAMILY SSF53649 459 634 1.86E-5 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HVS_RS01610 9fa8281f6a276fd2c9fbb69944c624bb 306 SUPERFAMILY SSF81345 15 274 4.84E-27 T 29-03-2018 IPR029022 ABC transporter, BtuC-like HVS_RS01610 9fa8281f6a276fd2c9fbb69944c624bb 306 Gene3D G3DSA:1.10.3470.10 4 284 3.0E-23 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like HVS_RS01610 9fa8281f6a276fd2c9fbb69944c624bb 306 Pfam PF00950 ABC 3 transport family 11 276 2.2E-74 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 HVS_RS02145 4bc8b19640ffe2f42569dbdba076c96c 175 SMART SM00448 3 113 6.8E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02145 4bc8b19640ffe2f42569dbdba076c96c 175 Gene3D G3DSA:1.10.10.10 121 175 3.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02145 4bc8b19640ffe2f42569dbdba076c96c 175 SUPERFAMILY SSF52172 4 167 2.56E-42 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS02145 4bc8b19640ffe2f42569dbdba076c96c 175 Pfam PF00072 Response regulator receiver domain 5 113 9.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02145 4bc8b19640ffe2f42569dbdba076c96c 175 Gene3D G3DSA:3.40.50.2300 2 120 7.0E-36 T 29-03-2018 HVS_RS09460 4b076879feaf568964e619b25302f603 187 Gene3D G3DSA:2.50.20.10 35 186 1.3E-11 T 29-03-2018 HVS_RS12775 c16ced3b0903747b3a0365895bf73b3c 605 Pfam PF01610 Transposase 475 595 1.1E-13 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS12775 c16ced3b0903747b3a0365895bf73b3c 605 Pfam PF01610 Transposase 167 293 1.1E-13 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS12775 c16ced3b0903747b3a0365895bf73b3c 605 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 90 8.4E-9 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HVS_RS12775 c16ced3b0903747b3a0365895bf73b3c 605 Gene3D G3DSA:1.10.10.60 331 390 9.1E-9 T 29-03-2018 HVS_RS02165 fbe902ad35623966c66a0550f2a3f897 366 SUPERFAMILY SSF56796 3 361 5.5E-87 T 29-03-2018 HVS_RS02165 fbe902ad35623966c66a0550f2a3f897 366 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 170 198 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HVS_RS02165 fbe902ad35623966c66a0550f2a3f897 366 Gene3D G3DSA:3.40.50.1970 2 181 1.4E-45 T 29-03-2018 HVS_RS02165 fbe902ad35623966c66a0550f2a3f897 366 Gene3D G3DSA:1.20.1090.10 183 364 5.4E-35 T 29-03-2018 HVS_RS02165 fbe902ad35623966c66a0550f2a3f897 366 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 313 3.6E-88 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 HVS_RS01615 0263eb58ccf1d4f841ff902bd3f51522 266 Pfam PF00005 ABC transporter 23 166 3.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS01615 0263eb58ccf1d4f841ff902bd3f51522 266 Gene3D G3DSA:3.40.50.300 2 249 7.8E-59 T 29-03-2018 HVS_RS01615 0263eb58ccf1d4f841ff902bd3f51522 266 SMART SM00382 30 214 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS01615 0263eb58ccf1d4f841ff902bd3f51522 266 SUPERFAMILY SSF52540 4 230 5.03E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00190 2bc2f73c200c609e891d2a80ed223a01 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HVS_RS00190 2bc2f73c200c609e891d2a80ed223a01 68 Pfam PF00403 Heavy-metal-associated domain 6 66 1.9E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HVS_RS00190 2bc2f73c200c609e891d2a80ed223a01 68 SUPERFAMILY SSF55008 1 67 3.01E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HVS_RS00190 2bc2f73c200c609e891d2a80ed223a01 68 Gene3D G3DSA:3.30.70.100 1 68 2.9E-20 T 29-03-2018 HVS_RS13365 99319c19538d2599a0d802c996a97d11 505 Gene3D G3DSA:3.30.420.10 138 316 2.7E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS13365 99319c19538d2599a0d802c996a97d11 505 Gene3D G3DSA:1.10.10.60 1 114 2.4E-7 T 29-03-2018 HVS_RS15550 6bcdb670acebe3e703b54e2010d8ba1a 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 1.9E-77 T 29-03-2018 HVS_RS15550 6bcdb670acebe3e703b54e2010d8ba1a 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 45.82 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HVS_RS15550 6bcdb670acebe3e703b54e2010d8ba1a 209 SUPERFAMILY SSF53271 4 207 4.06E-71 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS15550 6bcdb670acebe3e703b54e2010d8ba1a 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.3E-87 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HVS_RS15550 6bcdb670acebe3e703b54e2010d8ba1a 209 Gene3D G3DSA:3.40.50.2020 2 207 6.1E-63 T 29-03-2018 HVS_RS02985 f0864964511dc318edcf25c3941b5b60 120 PIRSF PIRSF019455 1 120 7.3E-22 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HVS_RS02985 f0864964511dc318edcf25c3941b5b60 120 Pfam PF03965 Penicillinase repressor 6 116 7.6E-21 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HVS_RS02985 f0864964511dc318edcf25c3941b5b60 120 SUPERFAMILY SSF46785 4 118 8.02E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02985 f0864964511dc318edcf25c3941b5b60 120 Gene3D G3DSA:1.10.10.10 7 70 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02985 f0864964511dc318edcf25c3941b5b60 120 Gene3D G3DSA:1.10.4040.10 71 116 1.2E-14 T 29-03-2018 HVS_RS00835 6ace2fc834f33db8596e37b8e6b19bfe 552 Pfam PF13401 AAA domain 127 273 3.6E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS00835 6ace2fc834f33db8596e37b8e6b19bfe 552 SUPERFAMILY SSF52540 125 370 1.64E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS00835 6ace2fc834f33db8596e37b8e6b19bfe 552 Gene3D G3DSA:3.40.50.300 64 284 7.4E-8 T 29-03-2018 HVS_RS07320 78e695bae1e0901fa6c58ee71fdc1341 321 Gene3D G3DSA:3.90.25.10 191 319 8.0E-26 T 29-03-2018 HVS_RS07320 78e695bae1e0901fa6c58ee71fdc1341 321 SUPERFAMILY SSF51735 3 315 4.72E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS07320 78e695bae1e0901fa6c58ee71fdc1341 321 Gene3D G3DSA:3.40.50.720 1 190 8.1E-28 T 29-03-2018 HVS_RS07320 78e695bae1e0901fa6c58ee71fdc1341 321 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 306 1.1E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS05760 ea607c0162f57594b58db9a1fdb08a29 631 Gene3D G3DSA:1.20.5.1230 462 616 1.9E-4 T 29-03-2018 HVS_RS05760 ea607c0162f57594b58db9a1fdb08a29 631 Gene3D G3DSA:1.20.5.1230 34 461 2.5E-4 T 29-03-2018 HVS_RS12625 562e6687cebd235f075c1fd1429217b2 236 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 56 182 3.5E-9 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 HVS_RS12625 562e6687cebd235f075c1fd1429217b2 236 Gene3D G3DSA:3.20.20.190 30 233 5.4E-18 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HVS_RS12625 562e6687cebd235f075c1fd1429217b2 236 SUPERFAMILY SSF51695 42 196 6.02E-18 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 HVS_RS06210 991e36c1e6387f22200b7eaa03366b34 173 Pfam PF04892 VanZ like family 19 154 7.0E-19 T 29-03-2018 IPR006976 VanZ-like HVS_RS14900 19b99742463a9deecd9afe85be886033 195 Gene3D G3DSA:1.10.443.10 3 195 7.4E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS14900 19b99742463a9deecd9afe85be886033 195 Pfam PF00589 Phage integrase family 6 175 1.8E-31 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS14900 19b99742463a9deecd9afe85be886033 195 SUPERFAMILY SSF56349 4 188 1.85E-40 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 42 58 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 145 166 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 121 145 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 245 271 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 23 42 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 397 414 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PRINTS PR01806 Virulence factor MviN signature 343 362 1.2E-35 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 454 15.339 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 493 6.8E-101 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 PIRSF PIRSF002869 1 499 1.9E-121 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS07510 9f5fe1f4b95d1087bcd0a7ef7cf7af1a 504 Pfam PF03023 MviN-like protein 20 453 1.1E-88 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ HVS_RS10150 b695b6fa1e6bc4575834b80342a47393 302 SUPERFAMILY SSF52540 33 277 1.19E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10150 b695b6fa1e6bc4575834b80342a47393 302 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 34 273 4.4E-22 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 HVS_RS10150 b695b6fa1e6bc4575834b80342a47393 302 Gene3D G3DSA:3.40.50.300 32 276 9.3E-51 T 29-03-2018 HVS_RS10150 b695b6fa1e6bc4575834b80342a47393 302 PIRSF PIRSF003092 2 302 1.6E-91 T 29-03-2018 IPR025501 ATP binding protein MinD HVS_RS11230 1ba37e50e101e7201bf1623e8d628522 644 Gene3D G3DSA:3.40.1000.10 249 405 3.9E-8 T 29-03-2018 HVS_RS11230 1ba37e50e101e7201bf1623e8d628522 644 Gene3D G3DSA:3.40.1000.10 409 580 6.1E-6 T 29-03-2018 HVS_RS06710 3f2cbf237c6d11f473339d1fc99f4d7c 328 Pfam PF07833 Copper amine oxidase N-terminal domain 49 141 2.1E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06710 3f2cbf237c6d11f473339d1fc99f4d7c 328 Gene3D G3DSA:3.30.457.10 62 123 6.0E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06710 3f2cbf237c6d11f473339d1fc99f4d7c 328 Gene3D G3DSA:3.30.457.10 9 61 2.6E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06710 3f2cbf237c6d11f473339d1fc99f4d7c 328 Gene3D G3DSA:3.30.457.10 124 278 9.1E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06710 3f2cbf237c6d11f473339d1fc99f4d7c 328 SUPERFAMILY SSF55383 52 135 4.05E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS10375 626070e863c1db431d080e67f4160f52 279 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS10375 626070e863c1db431d080e67f4160f52 279 SUPERFAMILY SSF52540 3 229 1.45E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10375 626070e863c1db431d080e67f4160f52 279 Pfam PF00005 ABC transporter 25 167 2.8E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS10375 626070e863c1db431d080e67f4160f52 279 Gene3D G3DSA:3.40.50.300 1 239 6.1E-60 T 29-03-2018 HVS_RS10375 626070e863c1db431d080e67f4160f52 279 SMART SM00382 31 223 6.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS04395 8cbd77d94d8961bcc13dc4d60e618504 250 Gene3D G3DSA:3.90.550.10 1 211 7.6E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS04395 8cbd77d94d8961bcc13dc4d60e618504 250 Pfam PF02348 Cytidylyltransferase 5 192 1.7E-28 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 HVS_RS04395 8cbd77d94d8961bcc13dc4d60e618504 250 SUPERFAMILY SSF53448 1 212 4.06E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS13035 be5fd27cb6c65eebf33b6c3a92b4b867 235 Pfam PF12679 ABC-2 family transporter protein 53 223 2.6E-8 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 HVS_RS09370 ccf8f3d3cdf67ba461f1adaf032933ee 277 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 38 274 3.0E-77 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase HVS_RS09370 ccf8f3d3cdf67ba461f1adaf032933ee 277 Gene3D G3DSA:3.60.140.10 11 277 2.3E-82 T 29-03-2018 HVS_RS09370 ccf8f3d3cdf67ba461f1adaf032933ee 277 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 43 276 3.4E-56 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase HVS_RS09370 ccf8f3d3cdf67ba461f1adaf032933ee 277 SUPERFAMILY SSF64438 19 276 3.51E-79 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic HVS_RS04370 336271f3042a885ad8f59662c1e460fe 482 Pfam PF04986 Putative transposase 167 336 2.1E-24 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS04370 336271f3042a885ad8f59662c1e460fe 482 Pfam PF14319 Transposase zinc-binding domain 32 140 6.1E-28 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS15955 d15f4255ef1199cef4ecf318ce4f7e16 492 Pfam PF07435 YycH protein 16 201 3.5E-8 T 29-03-2018 IPR009996 Regulatory protein YycH HVS_RS01270 b82e34ece070550efdb4b9c55e5707d9 337 SUPERFAMILY SSF103486 12 333 4.71E-69 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01270 b82e34ece070550efdb4b9c55e5707d9 337 Gene3D G3DSA:1.20.1690.10 84 179 2.0E-15 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01270 b82e34ece070550efdb4b9c55e5707d9 337 Gene3D G3DSA:1.20.1690.10 186 287 1.7E-12 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS01270 b82e34ece070550efdb4b9c55e5707d9 337 Pfam PF01992 ATP synthase (C/AC39) subunit 16 331 8.0E-64 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 HVS_RS09930 0eaa36942b2f90fdb2d1040956f6b1db 722 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 6 713 2.9E-221 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS09930 0eaa36942b2f90fdb2d1040956f6b1db 722 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 1 710 23.229 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS09930 0eaa36942b2f90fdb2d1040956f6b1db 722 Pfam PF03030 Inorganic H+ pyrophosphatase 12 704 1.4E-241 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS09930 0eaa36942b2f90fdb2d1040956f6b1db 722 PIRSF PIRSF001265 1 719 5.7E-242 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 HVS_RS06920 6fa6c6cf08729d073ac9e2cf73e88c42 70 Pfam PF06961 Protein of unknown function (DUF1294) 1 49 9.6E-22 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 HVS_RS07860 40f68a9230acdc0d6dfbd638f718c76f 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 4.9E-40 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type HVS_RS07860 40f68a9230acdc0d6dfbd638f718c76f 148 Pfam PF02082 Transcriptional regulator 1 82 4.2E-29 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type HVS_RS07860 40f68a9230acdc0d6dfbd638f718c76f 148 SUPERFAMILY SSF46785 2 135 1.7E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07860 40f68a9230acdc0d6dfbd638f718c76f 148 Gene3D G3DSA:1.10.10.10 1 148 2.5E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS07860 40f68a9230acdc0d6dfbd638f718c76f 148 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site HVS_RS07315 f2ae1465de8b19e2360d4c7a7b904922 87 Pfam PF11823 Protein of unknown function (DUF3343) 3 67 2.2E-8 T 29-03-2018 IPR021778 Domain of unknown function DUF3343 HVS_RS02520 6ad68c4b9b7bc1e458a4873d5cfc5c34 424 Gene3D G3DSA:2.60.40.680 31 174 3.6E-28 T 29-03-2018 HVS_RS02520 6ad68c4b9b7bc1e458a4873d5cfc5c34 424 Pfam PF00963 Cohesin domain 37 160 9.7E-29 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 HVS_RS02520 6ad68c4b9b7bc1e458a4873d5cfc5c34 424 Pfam PF00395 S-layer homology domain 224 244 4.7E-7 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS02520 6ad68c4b9b7bc1e458a4873d5cfc5c34 424 Pfam PF00395 S-layer homology domain 264 306 1.7E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS02520 6ad68c4b9b7bc1e458a4873d5cfc5c34 424 Pfam PF00395 S-layer homology domain 325 365 1.3E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS02520 6ad68c4b9b7bc1e458a4873d5cfc5c34 424 SUPERFAMILY SSF49384 36 173 2.88E-33 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 HVS_RS14370 e5fe8a5930fdea6d4a9b6e54267de144 222 Pfam PF07238 PilZ domain 99 198 3.2E-11 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS14370 e5fe8a5930fdea6d4a9b6e54267de144 222 SUPERFAMILY SSF141371 94 199 9.42E-8 T 29-03-2018 HVS_RS14370 e5fe8a5930fdea6d4a9b6e54267de144 222 Gene3D G3DSA:2.40.10.220 93 221 7.1E-20 T 29-03-2018 HVS_RS12205 6cc7365882403cc6418043605a584b40 125 Pfam PF17032 zinc-ribbon family 21 79 1.6E-10 T 29-03-2018 IPR031493 Zinc-ribbon 15 HVS_RS07335 d6e4a0606228c1d69e14052b466058b7 344 Gene3D G3DSA:3.30.200.20 3 97 5.7E-13 T 29-03-2018 HVS_RS07335 d6e4a0606228c1d69e14052b466058b7 344 Gene3D G3DSA:3.90.1200.10 100 337 1.8E-32 T 29-03-2018 HVS_RS07335 d6e4a0606228c1d69e14052b466058b7 344 SUPERFAMILY SSF56112 5 329 3.79E-38 T 29-03-2018 IPR011009 Protein kinase-like domain HVS_RS07335 d6e4a0606228c1d69e14052b466058b7 344 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 23 337 1.8E-96 T 29-03-2018 IPR014255 Spore coat protein CotS HVS_RS09775 092c6c7250656bd2e3831d62e2a0630a 270 SUPERFAMILY SSF53474 33 237 4.4E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS09775 092c6c7250656bd2e3831d62e2a0630a 270 Gene3D G3DSA:3.40.50.1820 31 266 1.6E-6 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS03475 9cadd9949707b079e700756b2e99499e 438 Gene3D G3DSA:1.20.1170.10 2 49 0.15 T 29-03-2018 HVS_RS03475 9cadd9949707b079e700756b2e99499e 438 Gene3D G3DSA:1.20.1480.30 50 129 0.003 T 29-03-2018 HVS_RS03475 9cadd9949707b079e700756b2e99499e 438 SUPERFAMILY SSF47090 177 255 1.57E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03475 9cadd9949707b079e700756b2e99499e 438 Gene3D G3DSA:1.10.101.10 182 260 1.3E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS03475 9cadd9949707b079e700756b2e99499e 438 Pfam PF01471 Putative peptidoglycan binding domain 191 254 9.0E-5 T 29-03-2018 IPR002477 Peptidoglycan binding-like HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 SUPERFAMILY SSF56796 5 340 1.57E-101 T 29-03-2018 HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 Pfam PF01761 3-dehydroquinate synthase 67 323 3.0E-101 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 357 39.216 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 25 350 3.1E-113 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 Gene3D G3DSA:3.40.50.1970 5 172 4.1E-45 T 29-03-2018 HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 Gene3D G3DSA:1.20.1090.10 173 360 1.6E-59 T 29-03-2018 HVS_RS07835 0e8a8c8287db964c7223d4e48da59ce9 360 PIRSF PIRSF001455 3 358 7.2E-112 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 HVS_RS15435 2abab00e000c0d3d16908b5384394a0c 133 Gene3D G3DSA:3.40.50.2300 1 133 2.8E-37 T 29-03-2018 HVS_RS15435 2abab00e000c0d3d16908b5384394a0c 133 SUPERFAMILY SSF52788 1 126 2.09E-37 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS15435 2abab00e000c0d3d16908b5384394a0c 133 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 124 2.8E-24 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS15435 2abab00e000c0d3d16908b5384394a0c 133 SMART SM00226 3 127 1.6E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS05720 7ae75b2c2735649a8627875db0ee0abf 282 SUPERFAMILY SSF55383 51 134 1.02E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05720 7ae75b2c2735649a8627875db0ee0abf 282 Gene3D G3DSA:3.30.457.10 61 122 2.8E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05720 7ae75b2c2735649a8627875db0ee0abf 282 Gene3D G3DSA:3.30.457.10 11 60 2.7E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05720 7ae75b2c2735649a8627875db0ee0abf 282 Gene3D G3DSA:3.30.457.10 123 201 6.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05720 7ae75b2c2735649a8627875db0ee0abf 282 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 1.0E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS08865 bac0ab554d8bdad61e19e696b2120f1f 331 Gene3D G3DSA:3.60.21.10 1 72 1.6E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS08865 bac0ab554d8bdad61e19e696b2120f1f 331 Gene3D G3DSA:3.60.21.10 73 251 1.1E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS08865 bac0ab554d8bdad61e19e696b2120f1f 331 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 239 4.9E-13 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 HVS_RS08865 bac0ab554d8bdad61e19e696b2120f1f 331 SUPERFAMILY SSF56300 1 245 7.33E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS02975 9ded38983c4be5ae0751fe2d9bd29db6 373 Gene3D G3DSA:1.10.260.40 13 115 3.6E-16 T 29-03-2018 HVS_RS02975 9ded38983c4be5ae0751fe2d9bd29db6 373 Pfam PF01381 Helix-turn-helix 20 72 6.7E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS02975 9ded38983c4be5ae0751fe2d9bd29db6 373 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 14 82 1.2E-15 T 29-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 HVS_RS02975 9ded38983c4be5ae0751fe2d9bd29db6 373 SUPERFAMILY SSF47413 15 89 1.35E-21 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HVS_RS02975 9ded38983c4be5ae0751fe2d9bd29db6 373 SMART SM00530 19 74 1.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HVS_RS10415 8cab68669bb9629a67122e6272d841dc 75 Gene3D G3DSA:3.40.50.300 1 71 5.2E-18 T 29-03-2018 HVS_RS10415 8cab68669bb9629a67122e6272d841dc 75 SUPERFAMILY SSF52540 3 60 2.75E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS10415 8cab68669bb9629a67122e6272d841dc 75 Pfam PF00005 ABC transporter 23 60 1.8E-11 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS14640 151eaa4cfb8fe90b00b594e15aa597b9 150 SUPERFAMILY SSF158397 31 149 5.49E-33 T 29-03-2018 HVS_RS14640 151eaa4cfb8fe90b00b594e15aa597b9 150 Gene3D G3DSA:1.20.120.490 32 149 4.2E-34 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain HVS_RS14640 151eaa4cfb8fe90b00b594e15aa597b9 150 Pfam PF03885 Protein of unknown function (DUF327) 13 149 7.4E-40 T 29-03-2018 IPR005585 Protein of unknown function DUF327 HVS_RS05735 7006882186434137e68457621d7d6395 195 Gene3D G3DSA:3.30.457.10 16 60 1.6E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05735 7006882186434137e68457621d7d6395 195 Gene3D G3DSA:3.30.457.10 123 182 1.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05735 7006882186434137e68457621d7d6395 195 Gene3D G3DSA:3.30.457.10 61 122 1.3E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05735 7006882186434137e68457621d7d6395 195 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 4.5E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05735 7006882186434137e68457621d7d6395 195 SUPERFAMILY SSF55383 51 134 4.58E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13980 d7a5ed299c46a307420df4655ee360bc 287 Gene3D G3DSA:3.30.457.10 24 71 3.9E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13980 d7a5ed299c46a307420df4655ee360bc 287 Gene3D G3DSA:3.30.457.10 132 212 4.6E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13980 d7a5ed299c46a307420df4655ee360bc 287 Gene3D G3DSA:3.30.457.10 72 131 2.0E-15 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13980 d7a5ed299c46a307420df4655ee360bc 287 SUPERFAMILY SSF55383 62 146 5.69E-16 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13980 d7a5ed299c46a307420df4655ee360bc 287 Pfam PF07833 Copper amine oxidase N-terminal domain 60 151 1.9E-20 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS12000 3789d501bb1aebe1ede3e72216b66bb1 434 SMART SM00854 84 333 6.2E-84 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA HVS_RS12000 3789d501bb1aebe1ede3e72216b66bb1 434 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 84 332 1.2E-71 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA HVS_RS12000 3789d501bb1aebe1ede3e72216b66bb1 434 Gene3D G3DSA:3.60.21.10 75 411 1.2E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS12000 3789d501bb1aebe1ede3e72216b66bb1 434 SUPERFAMILY SSF56300 83 338 7.21E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like HVS_RS12135 9fa6e8f25ceb5276017531893f57b48a 148 SMART SM01066 23 103 5.8E-32 T 29-03-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 HVS_RS12135 9fa6e8f25ceb5276017531893f57b48a 148 Pfam PF16760 Starch/carbohydrate-binding module (family 53) 27 102 1.3E-13 T 29-03-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 HVS_RS12135 9fa6e8f25ceb5276017531893f57b48a 148 Gene3D G3DSA:2.60.40.10 15 120 3.5E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS00505 4eafbde501bb07ae875424689ecab2ab 405 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 211 345 1.4E-28 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS00505 4eafbde501bb07ae875424689ecab2ab 405 Gene3D G3DSA:1.10.287.950 159 389 2.3E-36 T 29-03-2018 HVS_RS00505 4eafbde501bb07ae875424689ecab2ab 405 SMART SM00283 128 400 1.9E-8 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 HVS_RS00505 4eafbde501bb07ae875424689ecab2ab 405 SUPERFAMILY SSF58104 116 397 2.09E-47 T 29-03-2018 HVS_RS14610 7563a5ad3bd31f9393f2139095e40e8c 79 Gene3D G3DSA:2.10.260.10 1 48 1.4E-18 T 29-03-2018 HVS_RS14610 7563a5ad3bd31f9393f2139095e40e8c 79 SUPERFAMILY SSF89447 1 53 4.32E-16 T 29-03-2018 HVS_RS14610 7563a5ad3bd31f9393f2139095e40e8c 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 5.2E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS14610 7563a5ad3bd31f9393f2139095e40e8c 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 3.6E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS14610 7563a5ad3bd31f9393f2139095e40e8c 79 SMART SM00966 8 51 2.1E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 HVS_RS14385 5ddc6e540284f306cadbfe4e50a36f48 157 Gene3D G3DSA:3.40.630.30 1 151 3.0E-25 T 29-03-2018 HVS_RS14385 5ddc6e540284f306cadbfe4e50a36f48 157 Pfam PF00583 Acetyltransferase (GNAT) family 46 137 2.3E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 HVS_RS14385 5ddc6e540284f306cadbfe4e50a36f48 157 SUPERFAMILY SSF55729 5 147 7.86E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase HVS_RS11930 78968ed47bf439944eab34403551cb6e 280 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 10 280 4.0E-95 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HVS_RS11930 78968ed47bf439944eab34403551cb6e 280 Pfam PF05681 Fumarate hydratase (Fumerase) 11 278 2.4E-112 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 HVS_RS08945 fe5759b37141138ce89043471b201580 327 Pfam PF02621 Menaquinone biosynthesis 67 282 2.2E-13 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme HVS_RS08945 fe5759b37141138ce89043471b201580 327 Gene3D G3DSA:3.40.190.10 46 141 7.1E-5 T 29-03-2018 HVS_RS08945 fe5759b37141138ce89043471b201580 327 Gene3D G3DSA:3.40.190.10 142 310 5.0E-26 T 29-03-2018 HVS_RS08945 fe5759b37141138ce89043471b201580 327 PIRSF PIRSF027386 1 327 2.5E-107 T 29-03-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type HVS_RS08945 fe5759b37141138ce89043471b201580 327 SUPERFAMILY SSF53850 33 309 4.87E-41 T 29-03-2018 HVS_RS07420 c2fd2d0681c08880edbac872b22340ce 128 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 102 1.4E-17 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HVS_RS07420 c2fd2d0681c08880edbac872b22340ce 128 Gene3D G3DSA:3.40.140.10 1 128 1.6E-49 T 29-03-2018 HVS_RS07420 c2fd2d0681c08880edbac872b22340ce 128 SUPERFAMILY SSF53927 1 126 9.37E-47 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 HVS_RS07420 c2fd2d0681c08880edbac872b22340ce 128 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 127 1.1E-47 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 HVS_RS07420 c2fd2d0681c08880edbac872b22340ce 128 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HVS_RS07125 dfcb1bc2c1d05be2b72d8cf888be2018 352 Gene3D G3DSA:3.40.50.1220 1 352 7.7E-4 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS07125 dfcb1bc2c1d05be2b72d8cf888be2018 352 SUPERFAMILY SSF52467 172 347 7.01E-12 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS07125 dfcb1bc2c1d05be2b72d8cf888be2018 352 SUPERFAMILY SSF52467 80 144 7.01E-12 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS07125 dfcb1bc2c1d05be2b72d8cf888be2018 352 SUPERFAMILY SSF52467 2 35 7.01E-12 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 Gene3D G3DSA:1.10.10.10 123 226 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 SUPERFAMILY SSF52172 3 175 2.28E-36 T 29-03-2018 IPR011006 CheY-like superfamily HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 9.4E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 Gene3D G3DSA:3.40.50.2300 1 122 5.1E-33 T 29-03-2018 HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 SMART SM00448 3 112 2.5E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 SMART SM00862 146 221 5.5E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HVS_RS02995 f879d9d888f98e08c66edea5d45d83f3 232 Pfam PF00072 Response regulator receiver domain 5 112 4.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 HVS_RS07960 8551d847e1f0a338ac71bdfcc42721c4 280 SUPERFAMILY SSF52518 41 264 7.07E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold HVS_RS07960 8551d847e1f0a338ac71bdfcc42721c4 280 Gene3D G3DSA:3.40.50.970 28 115 6.1E-7 T 29-03-2018 HVS_RS07960 8551d847e1f0a338ac71bdfcc42721c4 280 Gene3D G3DSA:3.40.50.970 116 280 1.5E-27 T 29-03-2018 HVS_RS07960 8551d847e1f0a338ac71bdfcc42721c4 280 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 92 235 1.2E-22 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HVS_RS10940 7b20a17d0ac79e534e7b5f5318681401 214 Pfam PF01081 KDPG and KHG aldolase 8 200 1.0E-28 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 HVS_RS10940 7b20a17d0ac79e534e7b5f5318681401 214 Gene3D G3DSA:3.20.20.70 4 214 9.2E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS10940 7b20a17d0ac79e534e7b5f5318681401 214 SUPERFAMILY SSF51569 2 211 1.83E-45 T 29-03-2018 HVS_RS10565 64afc92e106bfae3ee0ed1abd85177e2 249 Pfam PF04015 Domain of unknown function (DUF362) 32 235 1.1E-37 T 29-03-2018 IPR007160 Domain of unknown function DUF362 HVS_RS12345 f6cb21053898384ef4ed919b4b4ccdd1 330 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 4 221 6.9E-62 T 29-03-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 HVS_RS16135 d009fdd44083fbea8ae0952097373e31 299 Gene3D G3DSA:3.20.20.370 52 298 3.8E-63 T 29-03-2018 HVS_RS16135 d009fdd44083fbea8ae0952097373e31 299 SUPERFAMILY SSF88713 95 294 3.64E-67 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HVS_RS16135 d009fdd44083fbea8ae0952097373e31 299 Pfam PF01522 Polysaccharide deacetylase 102 221 5.4E-35 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 HVS_RS13660 26ac65d26e45a63f89693a4a13ec4be9 432 Pfam PF14319 Transposase zinc-binding domain 15 121 8.7E-24 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS13660 26ac65d26e45a63f89693a4a13ec4be9 432 Pfam PF04986 Putative transposase 153 321 4.8E-39 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS05045 fac92fd52749e9a0e12f85a4f865ff32 159 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 32 149 4.0E-38 T 29-03-2018 IPR005562 SpoVA HVS_RS05045 fac92fd52749e9a0e12f85a4f865ff32 159 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 154 4.6E-61 T 29-03-2018 IPR014203 Sporulation stage V, protein AC HVS_RS05140 fbd4c2151ae67e523e0cc3f025fbafeb 226 SUPERFAMILY SSF55120 7 219 6.56E-55 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS05140 fbd4c2151ae67e523e0cc3f025fbafeb 226 Gene3D G3DSA:3.30.2350.10 6 222 2.6E-61 T 29-03-2018 HVS_RS05140 fbd4c2151ae67e523e0cc3f025fbafeb 226 Pfam PF00849 RNA pseudouridylate synthase 15 170 1.9E-34 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HVS_RS01005 05aa79f2fe6e07b10f97da39c44298a1 903 Gene3D G3DSA:3.40.50.1820 44 276 9.2E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS01005 05aa79f2fe6e07b10f97da39c44298a1 903 Gene3D G3DSA:1.20.120.20 658 884 3.8E-12 T 29-03-2018 HVS_RS01005 05aa79f2fe6e07b10f97da39c44298a1 903 Pfam PF11187 Protein of unknown function (DUF2974) 113 268 3.9E-21 T 29-03-2018 IPR024499 Protein of unknown function DUF2974 HVS_RS01005 05aa79f2fe6e07b10f97da39c44298a1 903 SUPERFAMILY SSF53474 135 276 2.61E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS01005 05aa79f2fe6e07b10f97da39c44298a1 903 Gene3D G3DSA:1.20.120.20 440 657 2.6E-8 T 29-03-2018 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 Gene3D G3DSA:3.30.70.1510 4 82 9.5E-25 T 29-03-2018 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 SUPERFAMILY SSF143437 3 175 5.06E-47 T 29-03-2018 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 377 1.5E-117 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 372 8.9E-73 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 Pfam PF02926 THUMP domain 41 159 1.5E-18 T 29-03-2018 IPR004114 THUMP domain GO:0003723 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 SMART SM00981 75 167 2.0E-22 T 29-03-2018 IPR004114 THUMP domain GO:0003723 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 Gene3D G3DSA:3.40.50.620 177 392 1.4E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 392 153.657 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 SUPERFAMILY SSF52402 176 382 6.62E-53 T 29-03-2018 HVS_RS07460 1f97a429178b364bb11ca426559461cd 392 Gene3D G3DSA:3.30.2300.10 83 165 3.3E-19 T 29-03-2018 HVS_RS02075 fd72bd4bf56866e60b633c8c6c68031c 495 SUPERFAMILY SSF52096 150 202 1.01E-27 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS02075 fd72bd4bf56866e60b633c8c6c68031c 495 SUPERFAMILY SSF52096 298 485 1.01E-27 T 29-03-2018 IPR029045 ClpP/crotonase-like domain HVS_RS02075 fd72bd4bf56866e60b633c8c6c68031c 495 Pfam PF03572 Peptidase family S41 304 478 5.9E-17 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS02075 fd72bd4bf56866e60b633c8c6c68031c 495 Gene3D G3DSA:3.90.226.10 277 495 9.3E-30 T 29-03-2018 HVS_RS02075 fd72bd4bf56866e60b633c8c6c68031c 495 SMART SM00245 276 480 0.0013 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 HVS_RS03370 f873218ac03094b1a4f33c8dc900d6e4 447 Pfam PF03611 PTS system sugar-specific permease component 11 390 4.1E-67 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 HVS_RS03370 f873218ac03094b1a4f33c8dc900d6e4 447 PIRSF PIRSF006304 4 447 9.6E-128 T 29-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 HVS_RS12255 237b04465532d1b517dc802a50a17e42 585 Gene3D G3DSA:2.60.40.10 469 563 0.12 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS12255 237b04465532d1b517dc802a50a17e42 585 Gene3D G3DSA:2.60.40.810 355 468 1.0E-6 T 29-03-2018 HVS_RS12655 668d49b74dc239cef22d73469c727cf3 242 Pfam PF07786 Protein of unknown function (DUF1624) 8 217 5.6E-58 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 SUPERFAMILY SSF51306 24 178 8.11E-45 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 149 2.2E-13 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 2.2E-13 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 82 94 2.2E-13 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 Pfam PF00717 Peptidase S24-like 31 106 3.1E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 173 8.3E-43 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HVS_RS11150 4529bf1f8058cb4f070685f23a0bb4ae 180 Gene3D G3DSA:2.10.109.10 20 179 8.8E-44 T 29-03-2018 HVS_RS15405 296f99eceb7d525c30816f85b6795d13 204 Pfam PF04199 Putative cyclase 5 148 7.8E-23 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 HVS_RS15405 296f99eceb7d525c30816f85b6795d13 204 SUPERFAMILY SSF102198 1 203 5.36E-53 T 29-03-2018 HVS_RS15405 296f99eceb7d525c30816f85b6795d13 204 Gene3D G3DSA:3.50.30.50 1 204 1.0E-50 T 29-03-2018 HVS_RS11790 ace8c8214c21248bc50eeb4320c1bb6f 400 Pfam PF13200 Putative glycosyl hydrolase domain 75 392 1.6E-113 T 29-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 HVS_RS11790 ace8c8214c21248bc50eeb4320c1bb6f 400 Gene3D G3DSA:3.20.20.80 81 290 9.4E-17 T 29-03-2018 HVS_RS11790 ace8c8214c21248bc50eeb4320c1bb6f 400 SUPERFAMILY SSF51445 132 295 3.99E-10 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS00875 6e9486ae2974d56021676b55256a960f 127 PIRSF PIRSF033725 1 127 6.8E-22 T 29-03-2018 IPR017020 Uncharacterised conserved protein UCP033725 HVS_RS00005 dc2d09073ac9c412e8e5d77af08a82c6 44 Pfam PF11638 DnaA N-terminal domain 6 44 7.8E-8 T 29-03-2018 IPR024633 DnaA N-terminal domain HVS_RS06785 d00f5d2b726aaf340e756326887cc036 361 Pfam PF04754 Putative transposase, YhgA-like 9 211 3.4E-34 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like HVS_RS10425 f3a98c8c4fdec0755d50864e0b0f5b47 119 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 113 1.5E-19 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS10425 f3a98c8c4fdec0755d50864e0b0f5b47 119 Gene3D G3DSA:3.65.10.10 1 116 3.5E-20 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 HVS_RS10425 f3a98c8c4fdec0755d50864e0b0f5b47 119 SUPERFAMILY SSF55205 1 115 7.36E-28 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HVS_RS06510 ee9cc368604972c2dadc9bdf34e84ff4 386 Pfam PF04326 Putative DNA-binding domain 14 122 8.9E-25 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 HVS_RS06510 ee9cc368604972c2dadc9bdf34e84ff4 386 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 297 383 5.0E-26 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain HVS_RS09830 09184808427cdc014ba0fd4029af709c 206 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 167 2.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat HVS_RS09830 09184808427cdc014ba0fd4029af709c 206 Gene3D G3DSA:3.40.50.20 1 74 1.8E-8 T 29-03-2018 HVS_RS09830 09184808427cdc014ba0fd4029af709c 206 SUPERFAMILY SSF51161 2 206 2.36E-30 T 29-03-2018 IPR011004 Trimeric LpxA-like HVS_RS09830 09184808427cdc014ba0fd4029af709c 206 Gene3D G3DSA:2.160.10.10 75 206 1.5E-23 T 29-03-2018 HVS_RS09830 09184808427cdc014ba0fd4029af709c 206 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 2 206 1.0E-48 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like HVS_RS14935 3b6236b0b9b19cb5f859c7090dc761f0 156 Gene3D G3DSA:3.30.1330.50 1 156 9.6E-43 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HVS_RS14935 3b6236b0b9b19cb5f859c7090dc761f0 156 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 8.2E-46 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HVS_RS14935 3b6236b0b9b19cb5f859c7090dc761f0 156 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 38 53 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HVS_RS14935 3b6236b0b9b19cb5f859c7090dc761f0 156 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 155 21.157 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HVS_RS14935 3b6236b0b9b19cb5f859c7090dc761f0 156 Pfam PF02542 YgbB family 1 155 2.0E-43 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HVS_RS14935 3b6236b0b9b19cb5f859c7090dc761f0 156 SUPERFAMILY SSF69765 1 155 7.06E-43 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 HVS_RS03835 7253f0914891584b03e7af0a206540fb 195 PIRSF PIRSF015278 26 194 7.2E-37 T 29-03-2018 IPR016630 Uncharacterised conserved protein UCP015278 HVS_RS03835 7253f0914891584b03e7af0a206540fb 195 Pfam PF10004 Uncharacterized protein conserved in bacteria (DUF2247) 33 189 1.2E-33 T 29-03-2018 IPR016630 Uncharacterised conserved protein UCP015278 HVS_RS11095 d214f661f27e2e72518863ec01ee6231 313 PIRSF PIRSF000401 1 311 9.7E-100 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HVS_RS11095 d214f661f27e2e72518863ec01ee6231 313 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 308 7.1E-97 T 29-03-2018 HVS_RS11095 d214f661f27e2e72518863ec01ee6231 313 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 309 34.141 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HVS_RS11095 d214f661f27e2e72518863ec01ee6231 313 SUPERFAMILY SSF53335 99 307 3.67E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS11095 d214f661f27e2e72518863ec01ee6231 313 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 303 2.0E-79 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HVS_RS11095 d214f661f27e2e72518863ec01ee6231 313 Gene3D G3DSA:3.40.50.150 116 312 1.3E-38 T 29-03-2018 HVS_RS08545 302da0fcfecc6fb9314dd8472c9b0589 204 Pfam PF10776 Protein of unknown function (DUF2600) 21 204 4.4E-62 T 29-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 HVS_RS05740 76d214da6a8ef3da23977b2da902210d 282 Pfam PF07833 Copper amine oxidase N-terminal domain 49 140 1.0E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05740 76d214da6a8ef3da23977b2da902210d 282 Gene3D G3DSA:3.30.457.10 60 122 3.1E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05740 76d214da6a8ef3da23977b2da902210d 282 Gene3D G3DSA:3.30.457.10 12 59 4.5E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05740 76d214da6a8ef3da23977b2da902210d 282 Gene3D G3DSA:3.30.457.10 123 201 7.2E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS05740 76d214da6a8ef3da23977b2da902210d 282 SUPERFAMILY SSF55383 51 134 1.02E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01650 42ba93fff3f70bc41f174558e3f1a441 191 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 24.947 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 HVS_RS01650 42ba93fff3f70bc41f174558e3f1a441 191 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 190 1.9E-79 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 HVS_RS01650 42ba93fff3f70bc41f174558e3f1a441 191 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 190 2.1E-60 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HVS_RS01650 42ba93fff3f70bc41f174558e3f1a441 191 PIRSF PIRSF006102 1 191 1.7E-59 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 HVS_RS07165 6b99f92d08d3aaab9bbaa2d07b73608c 432 Pfam PF01964 Radical SAM ThiC family 4 421 6.8E-197 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HVS_RS07165 6b99f92d08d3aaab9bbaa2d07b73608c 432 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 4 422 1.4E-178 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HVS_RS07165 6b99f92d08d3aaab9bbaa2d07b73608c 432 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 3 427 54.34 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 HVS_RS05240 ddddef7ab6f6b70c2d4184eeea250ede 395 Pfam PF01139 tRNA-splicing ligase RtcB 34 116 1.6E-13 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HVS_RS05240 ddddef7ab6f6b70c2d4184eeea250ede 395 Pfam PF01139 tRNA-splicing ligase RtcB 128 393 9.7E-52 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HVS_RS05240 ddddef7ab6f6b70c2d4184eeea250ede 395 SUPERFAMILY SSF103365 5 393 1.01E-102 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 HVS_RS02725 0cc9d4f0962abcb30b889c7f56908b7b 144 SUPERFAMILY SSF55874 46 139 1.07E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02725 0cc9d4f0962abcb30b889c7f56908b7b 144 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 53 141 1.2E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02725 0cc9d4f0962abcb30b889c7f56908b7b 144 Gene3D G3DSA:3.30.565.10 47 144 1.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS02725 0cc9d4f0962abcb30b889c7f56908b7b 144 SMART SM00387 48 143 9.6E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS11310 ee654133f3a047409145280bb45ecdd9 195 Pfam PF17248 Family of unknown function (DUF5317) 30 180 6.0E-44 T 29-03-2018 IPR035168 Protein of unknown function DUF5317 HVS_RS02780 d8786e54fb793fea03b8dbf74b7f29d2 95 TIGRFAM TIGR04540 CLB_0814_fam: conserved hypothetical protein 18 89 1.8E-22 T 29-03-2018 IPR030902 Conserved hypothetical protein HVS_RS13305 d8786e54fb793fea03b8dbf74b7f29d2 95 TIGRFAM TIGR04540 CLB_0814_fam: conserved hypothetical protein 18 89 1.8E-22 T 29-03-2018 IPR030902 Conserved hypothetical protein HVS_RS04315 5e8dc8a5fa3fe3621a72bb46ad370038 482 Pfam PF14319 Transposase zinc-binding domain 32 140 1.1E-27 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS04315 5e8dc8a5fa3fe3621a72bb46ad370038 482 Pfam PF04986 Putative transposase 167 336 2.1E-24 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 8.8E-7 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 PRINTS PR01713 Nucleotide sugar epimerase signature 282 299 8.8E-7 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 PRINTS PR01713 Nucleotide sugar epimerase signature 239 254 8.8E-7 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 SUPERFAMILY SSF51735 2 327 1.86E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 Gene3D G3DSA:3.40.50.720 1 193 6.6E-42 T 29-03-2018 HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 311 1.4E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 8 303 1.6E-150 T 29-03-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family HVS_RS09850 af7e474bba5ca72f637db576352747f5 336 Gene3D G3DSA:3.90.25.10 194 335 4.1E-31 T 29-03-2018 HVS_RS04965 8584378c16564665f6253ed408857513 165 Pfam PF01930 Domain of unknown function DUF83 7 165 8.8E-55 T 29-03-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 HVS_RS04965 8584378c16564665f6253ed408857513 165 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 6 164 7.2E-28 T 29-03-2018 IPR013343 CRISPR-associated protein Cas4 HVS_RS05485 2988c4b1709bbfb9eff6ce345e36fc00 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 2.2E-88 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 SUPERFAMILY SSF48208 4 375 1.07E-109 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 PRINTS PR00735 Glycosyl hydrolase family 8 signature 355 369 1.1E-12 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 PRINTS PR00735 Glycosyl hydrolase family 8 signature 234 245 1.1E-12 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 PRINTS PR00735 Glycosyl hydrolase family 8 signature 122 140 1.1E-12 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 PRINTS PR00735 Glycosyl hydrolase family 8 signature 63 76 1.1E-12 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 PRINTS PR00735 Glycosyl hydrolase family 8 signature 191 208 1.1E-12 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 Gene3D G3DSA:1.50.10.10 1 370 7.4E-124 T 29-03-2018 HVS_RS07725 a43301ca403db63ae4023bee5d5500b4 376 Pfam PF01270 Glycosyl hydrolases family 8 57 367 1.8E-25 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 HVS_RS10640 3530412c8c4d7271f746f961fbb07bcd 223 Gene3D G3DSA:3.40.50.1000 5 218 3.6E-10 T 29-03-2018 IPR023214 HAD-like domain HVS_RS10640 3530412c8c4d7271f746f961fbb07bcd 223 Pfam PF12710 haloacid dehalogenase-like hydrolase 19 145 5.6E-9 T 29-03-2018 HVS_RS10640 3530412c8c4d7271f746f961fbb07bcd 223 SUPERFAMILY SSF56784 9 32 2.71E-12 T 29-03-2018 IPR023214 HAD-like domain HVS_RS10640 3530412c8c4d7271f746f961fbb07bcd 223 SUPERFAMILY SSF56784 75 205 2.71E-12 T 29-03-2018 IPR023214 HAD-like domain HVS_RS05530 fc3c061d6f6e5d75dd60854b117e9ae6 288 Pfam PF00482 Type II secretion system (T2SS), protein F 149 279 1.3E-12 T 29-03-2018 IPR018076 Type II secretion system F domain HVS_RS08740 433e98a076102211d4e51d8383196535 337 Pfam PF00793 DAHP synthetase I family 87 331 9.1E-77 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 HVS_RS08740 433e98a076102211d4e51d8383196535 337 Gene3D G3DSA:3.20.20.70 71 333 1.7E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS08740 433e98a076102211d4e51d8383196535 337 Gene3D G3DSA:3.30.70.1140 1 70 3.1E-23 T 29-03-2018 HVS_RS08740 433e98a076102211d4e51d8383196535 337 SUPERFAMILY SSF51569 1 335 1.01E-121 T 29-03-2018 HVS_RS08740 433e98a076102211d4e51d8383196535 337 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 71 328 6.2E-125 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 HVS_RS07045 b0e600f27f82024005bc697140f5265e 227 Pfam PF04298 Putative neutral zinc metallopeptidase 7 222 1.5E-90 T 29-03-2018 IPR007395 Putative neutral zinc metallopeptidase HVS_RS00230 85fec31dc4e154d5b9073e01025a7d7b 331 Pfam PF02517 CAAX protease self-immunity 134 218 3.8E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 HVS_RS12510 2e5ec5613071ed8995b308d5d8abf8e3 283 Gene3D G3DSA:1.10.10.630 176 261 0.0014 T 29-03-2018 IPR034829 DnaD-like domain HVS_RS14260 a6c2115e285d2117a7f24aa3d9717c59 286 Pfam PF00404 Dockerin type I repeat 46 66 2.7E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS14260 a6c2115e285d2117a7f24aa3d9717c59 286 SUPERFAMILY SSF63446 42 111 1.37E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS14260 a6c2115e285d2117a7f24aa3d9717c59 286 Gene3D G3DSA:1.10.1330.10 39 113 1.7E-7 T 29-03-2018 HVS_RS10720 9f86dca098283f42d7655b6d2e3f4720 65 Gene3D G3DSA:3.30.70.1530 5 65 9.5E-4 T 29-03-2018 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 PRINTS PR01837 MgtC/SapB protein signature 74 96 9.5E-43 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 PRINTS PR01837 MgtC/SapB protein signature 42 60 9.5E-43 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 PRINTS PR01837 MgtC/SapB protein signature 101 125 9.5E-43 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 PRINTS PR01837 MgtC/SapB protein signature 23 42 9.5E-43 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 Pfam PF02308 MgtC family 21 147 9.7E-39 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 SUPERFAMILY SSF55021 157 228 4.96E-7 T 29-03-2018 HVS_RS14210 6de3c22ad7726671a70c6e0c82bb0465 230 Gene3D G3DSA:3.30.70.260 156 229 4.4E-7 T 29-03-2018 HVS_RS08010 90079060baabb197b7fc568b7c663645 343 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 80 233 8.4E-34 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HVS_RS08010 90079060baabb197b7fc568b7c663645 343 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 80 232 1.6E-34 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HVS_RS15830 ba23443dcdfa7afbf227d576996b2d73 369 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 8 343 1.8E-109 T 29-03-2018 IPR014225 Sporulation stage II, protein D firmicutes HVS_RS15830 ba23443dcdfa7afbf227d576996b2d73 369 Pfam PF08486 Stage II sporulation protein 68 174 3.3E-26 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal HVS_RS15830 ba23443dcdfa7afbf227d576996b2d73 369 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 342 7.3E-73 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 HVS_RS15665 0ac3818baaf398351e71bff27571359c 219 SUPERFAMILY SSF53335 25 132 4.65E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS15665 0ac3818baaf398351e71bff27571359c 219 Pfam PF02390 Putative methyltransferase 27 107 1.8E-8 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 HVS_RS15665 0ac3818baaf398351e71bff27571359c 219 Gene3D G3DSA:3.40.50.150 20 215 3.6E-12 T 29-03-2018 HVS_RS02245 2a1a15957dc9c634de16e9084cc0ebca 300 Gene3D G3DSA:3.30.460.10 151 249 1.1E-5 T 29-03-2018 HVS_RS08635 d24bbc82036c6eabf95de2a38f96bef3 182 Pfam PF03780 Asp23 family, cell envelope-related function 118 173 4.9E-8 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 HVS_RS02645 890e2a1ece6ff00037850933917aa46f 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 227 9.1E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS02645 890e2a1ece6ff00037850933917aa46f 236 Gene3D G3DSA:1.10.3720.10 17 234 4.3E-19 T 29-03-2018 HVS_RS02645 890e2a1ece6ff00037850933917aa46f 236 SUPERFAMILY SSF161098 67 225 9.55E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS13300 03fb6adf63c5beeb1a49638eb2784a13 598 Pfam PF03235 Protein of unknown function DUF262 23 218 1.5E-31 T 29-03-2018 IPR004919 Domain of unknown function DUF262 HVS_RS11535 6cb891d2d5576bf687bc74fd08c2f78f 227 Gene3D G3DSA:3.30.70.20 169 227 3.6E-7 T 29-03-2018 HVS_RS11535 6cb891d2d5576bf687bc74fd08c2f78f 227 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 161 172 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HVS_RS11535 6cb891d2d5576bf687bc74fd08c2f78f 227 Gene3D G3DSA:3.30.70.20 77 168 0.011 T 29-03-2018 HVS_RS11535 6cb891d2d5576bf687bc74fd08c2f78f 227 Pfam PF13484 4Fe-4S double cluster binding domain 161 222 2.1E-7 T 29-03-2018 HVS_RS11535 6cb891d2d5576bf687bc74fd08c2f78f 227 SUPERFAMILY SSF46548 120 226 2.3E-10 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 HVS_RS03330 aca559889ee7cb08ba98f6395fff9441 302 Pfam PF03547 Membrane transport protein 157 298 1.0E-16 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 HVS_RS03330 aca559889ee7cb08ba98f6395fff9441 302 Pfam PF03547 Membrane transport protein 8 151 1.5E-20 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 Gene3D G3DSA:3.40.50.300 51 138 3.9E-5 T 29-03-2018 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 Gene3D G3DSA:3.30.230.10 547 780 9.9E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 SUPERFAMILY SSF52540 33 105 2.91E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 SUPERFAMILY SSF52540 311 568 2.91E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 62 81 4.9E-16 T 29-03-2018 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 681 700 4.9E-16 T 29-03-2018 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 570 586 4.9E-16 T 29-03-2018 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 711 729 4.9E-16 T 29-03-2018 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 651 670 4.9E-16 T 29-03-2018 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 SUPERFAMILY SSF52540 56 232 3.9E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 654 757 5.7E-9 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 Gene3D G3DSA:3.90.1150.10 139 201 2.2E-4 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 SUPERFAMILY SSF54211 569 762 2.12E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold HVS_RS03180 3fe69df8876849c1b7b8d42c1aabc6c9 801 Pfam PF13654 AAA domain 28 544 9.7E-211 T 29-03-2018 HVS_RS05585 8c8d9353e3b9834143e452602db99daa 451 Gene3D G3DSA:3.40.50.300 187 450 1.7E-11 T 29-03-2018 HVS_RS05585 8c8d9353e3b9834143e452602db99daa 451 SUPERFAMILY SSF52540 189 433 9.79E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08585 642934bbf29c17b8349e636b4f1aee2b 233 Gene3D G3DSA:3.40.50.300 1 216 1.7E-55 T 29-03-2018 HVS_RS08585 642934bbf29c17b8349e636b4f1aee2b 233 Pfam PF13500 AAA domain 3 207 2.9E-48 T 29-03-2018 HVS_RS08585 642934bbf29c17b8349e636b4f1aee2b 233 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 177 4.1E-48 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 HVS_RS08585 642934bbf29c17b8349e636b4f1aee2b 233 PIRSF PIRSF006755 1 231 1.0E-68 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 HVS_RS08585 642934bbf29c17b8349e636b4f1aee2b 233 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 210 28.191 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 HVS_RS08585 642934bbf29c17b8349e636b4f1aee2b 233 SUPERFAMILY SSF52540 1 209 1.59E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03760 b2a99400d4386e5557cb256d792a238e 99 SUPERFAMILY SSF50465 4 98 3.6E-5 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HVS_RS05930 0a10232280715aae1f0b833df545f458 349 Pfam PF01594 AI-2E family transporter 12 344 1.3E-70 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like HVS_RS08305 08ec89924a6c1dfa55db57cc79db3d5d 229 Gene3D G3DSA:3.40.50.360 1 229 3.8E-27 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS08305 08ec89924a6c1dfa55db57cc79db3d5d 229 Pfam PF03358 NADPH-dependent FMN reductase 1 145 3.0E-13 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HVS_RS08305 08ec89924a6c1dfa55db57cc79db3d5d 229 SUPERFAMILY SSF52218 1 183 4.19E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS11480 8323294fd6c1387d09f81c143e054251 199 SUPERFAMILY SSF52972 1 194 4.45E-71 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HVS_RS11480 8323294fd6c1387d09f81c143e054251 199 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 195 50.436 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 HVS_RS11480 8323294fd6c1387d09f81c143e054251 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 193 2.7E-59 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 HVS_RS11480 8323294fd6c1387d09f81c143e054251 199 Pfam PF01725 Ham1 family 5 191 5.2E-60 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 HVS_RS11480 8323294fd6c1387d09f81c143e054251 199 Gene3D G3DSA:3.90.950.10 1 198 9.2E-81 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like HVS_RS07365 d0b35bcc2520d94d2d7d37fcf03f33a6 241 Pfam PF05949 Bacterial protein of unknown function (DUF881) 92 227 2.8E-31 T 29-03-2018 IPR010273 Protein of unknown function DUF881 HVS_RS09575 3966efe51ca00f34fb7f49f2d9a6b81d 349 Gene3D G3DSA:3.10.450.50 192 345 1.2E-4 T 29-03-2018 HVS_RS09575 3966efe51ca00f34fb7f49f2d9a6b81d 349 SUPERFAMILY SSF103642 326 344 9.32E-6 T 29-03-2018 HVS_RS09575 3966efe51ca00f34fb7f49f2d9a6b81d 349 Pfam PF02810 SEC-C motif 327 344 9.0E-7 T 29-03-2018 IPR004027 SEC-C motif HVS_RS09575 3966efe51ca00f34fb7f49f2d9a6b81d 349 Pfam PF06685 Protein of unknown function (DUF1186) 5 244 2.1E-64 T 29-03-2018 IPR010602 Protein of unknown function DUF1186 HVS_RS15510 2b4bbc9ea82c9836777dfbdddd4f9f78 198 Gene3D G3DSA:1.20.1260.10 21 182 6.8E-41 T 29-03-2018 IPR012347 Ferritin-related HVS_RS15510 2b4bbc9ea82c9836777dfbdddd4f9f78 198 Pfam PF05067 Manganese containing catalase 29 181 6.8E-48 T 29-03-2018 IPR007760 Manganese catalase HVS_RS15510 2b4bbc9ea82c9836777dfbdddd4f9f78 198 SUPERFAMILY SSF47240 29 188 9.86E-58 T 29-03-2018 IPR009078 Ferritin-like superfamily HVS_RS02435 22ccca8fe4f612bf8d031e8fd46049d6 425 Pfam PF01882 Protein of unknown function DUF58 202 252 1.0E-13 T 29-03-2018 IPR002881 Domain of unknown function DUF58 HVS_RS02720 f7a5690bf16f7fd4618932e6d7c73a97 117 Pfam PF07085 DRTGG domain 5 97 1.1E-10 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 HVS_RS02720 f7a5690bf16f7fd4618932e6d7c73a97 117 Gene3D G3DSA:3.40.1390.20 1 108 1.0E-17 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HVS_RS02720 f7a5690bf16f7fd4618932e6d7c73a97 117 SUPERFAMILY SSF75138 1 107 6.41E-24 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HVS_RS05560 9cd79b0aeb8e2b098c1ad437daab4c1b 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 4.5E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS04635 9cd79b0aeb8e2b098c1ad437daab4c1b 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 4.5E-91 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS06725 7d2905d7ee75f7ab74b0fe82ae802ffd 87 Pfam PF07833 Copper amine oxidase N-terminal domain 1 40 6.0E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06725 7d2905d7ee75f7ab74b0fe82ae802ffd 87 Gene3D G3DSA:3.30.457.10 1 80 1.1E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07145 bc81843794f5cfa0ec177bdcb72e26c8 260 Gene3D G3DSA:3.20.20.70 7 260 1.7E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS07145 bc81843794f5cfa0ec177bdcb72e26c8 260 Pfam PF05690 Thiazole biosynthesis protein ThiG 12 254 2.3E-108 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 HVS_RS07145 bc81843794f5cfa0ec177bdcb72e26c8 260 SUPERFAMILY SSF110399 8 242 4.71E-81 T 29-03-2018 HVS_RS07145 bc81843794f5cfa0ec177bdcb72e26c8 260 Hamap MF_00443 Thiazole synthase [thiG]. 9 260 40.692 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 HVS_RS14125 1f99d489fea20e10cf66c3ddf17b8d88 176 Pfam PF04308 Ribonuclease H-like 28 174 2.4E-50 T 29-03-2018 IPR007405 Bacteriophage KVP40, Orf299 HVS_RS12700 378bbfb245174b2c2dd4ae2c2cf024fb 208 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 5 195 3.6E-66 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 HVS_RS12700 378bbfb245174b2c2dd4ae2c2cf024fb 208 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 7 195 34.375 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 HVS_RS12700 378bbfb245174b2c2dd4ae2c2cf024fb 208 SUPERFAMILY SSF50486 4 199 5.73E-68 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 HVS_RS12700 378bbfb245174b2c2dd4ae2c2cf024fb 208 Gene3D G3DSA:3.10.300.10 2 203 9.1E-77 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 HVS_RS12700 378bbfb245174b2c2dd4ae2c2cf024fb 208 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 8 192 1.7E-65 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 HVS_RS07670 b384e4023b5ed7b1c8a625387a4cb257 356 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 110 287 2.8E-22 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HVS_RS07670 b384e4023b5ed7b1c8a625387a4cb257 356 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 110 287 2.1E-27 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain HVS_RS15600 271b46ff06f2b13ba596a93d9170564c 408 Pfam PF00999 Sodium/hydrogen exchanger family 9 369 4.1E-35 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HVS_RS06795 7c66a4071f1f52f2dc27e0b8b7e8c52d 328 Pfam PF07833 Copper amine oxidase N-terminal domain 49 141 2.1E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06795 7c66a4071f1f52f2dc27e0b8b7e8c52d 328 Gene3D G3DSA:3.30.457.10 62 122 9.7E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06795 7c66a4071f1f52f2dc27e0b8b7e8c52d 328 Gene3D G3DSA:3.30.457.10 9 61 6.7E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06795 7c66a4071f1f52f2dc27e0b8b7e8c52d 328 Gene3D G3DSA:3.30.457.10 123 295 2.5E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS06795 7c66a4071f1f52f2dc27e0b8b7e8c52d 328 SUPERFAMILY SSF55383 52 135 4.05E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS01590 9dd4190d0637778c8232b7f6e44add27 598 SUPERFAMILY SSF55486 5 580 1.14E-126 T 29-03-2018 HVS_RS01590 9dd4190d0637778c8232b7f6e44add27 598 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 7 595 5.2E-211 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 HVS_RS01590 9dd4190d0637778c8232b7f6e44add27 598 Gene3D G3DSA:1.10.1370.10 311 596 9.6E-27 T 29-03-2018 HVS_RS01590 9dd4190d0637778c8232b7f6e44add27 598 Pfam PF08439 Oligopeptidase F 114 183 3.8E-23 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain HVS_RS01590 9dd4190d0637778c8232b7f6e44add27 598 Gene3D G3DSA:1.10.287.830 183 226 7.4E-19 T 29-03-2018 HVS_RS01590 9dd4190d0637778c8232b7f6e44add27 598 Pfam PF01432 Peptidase family M3 204 583 2.7E-74 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 HVS_RS00410 c46bbd98601275a24571fb7b862a465d 209 SUPERFAMILY SSF56784 1 206 2.67E-40 T 29-03-2018 IPR023214 HAD-like domain HVS_RS00410 c46bbd98601275a24571fb7b862a465d 209 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 170 1.8E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HVS_RS00410 c46bbd98601275a24571fb7b862a465d 209 Gene3D G3DSA:3.40.50.1000 3 185 7.0E-26 T 29-03-2018 IPR023214 HAD-like domain HVS_RS00410 c46bbd98601275a24571fb7b862a465d 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 1.6E-34 T 29-03-2018 IPR023214 HAD-like domain HVS_RS05400 78bf675d0c9c191859011a36c5de564f 266 Gene3D G3DSA:3.40.50.300 1 244 2.8E-54 T 29-03-2018 HVS_RS05400 78bf675d0c9c191859011a36c5de564f 266 Pfam PF13614 AAA domain 3 162 1.4E-22 T 29-03-2018 IPR025669 AAA domain HVS_RS05400 78bf675d0c9c191859011a36c5de564f 266 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 261 8.2E-126 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 HVS_RS05400 78bf675d0c9c191859011a36c5de564f 266 SUPERFAMILY SSF52540 1 247 2.03E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS05400 78bf675d0c9c191859011a36c5de564f 266 PIRSF PIRSF003092 1 266 1.1E-92 T 29-03-2018 IPR025501 ATP binding protein MinD HVS_RS07015 e7408db1ed86e2101ed8d9c2f8fefcfb 170 PIRSF PIRSF027391 1 169 3.0E-45 T 29-03-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I HVS_RS07015 e7408db1ed86e2101ed8d9c2f8fefcfb 170 Pfam PF07456 Heptaprenyl diphosphate synthase component I 13 159 4.4E-46 T 29-03-2018 IPR010898 Heptaprenyl diphosphate synthase component I HVS_RS05235 2e91397672a2ec89452bff24ee98b8ad 390 SUPERFAMILY SSF53474 70 341 6.18E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS05235 2e91397672a2ec89452bff24ee98b8ad 390 SUPERFAMILY SSF53474 2 13 6.18E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS05235 2e91397672a2ec89452bff24ee98b8ad 390 Gene3D G3DSA:3.40.50.1820 1 370 2.7E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS05235 2e91397672a2ec89452bff24ee98b8ad 390 Pfam PF02450 Lecithin:cholesterol acyltransferase 85 243 1.2E-24 T 29-03-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 HVS_RS06570 f584ea6149ce4a337286b3aa057e2f9a 78 Pfam PF16111 Domain of unknown function (DUF4829) 10 75 4.1E-10 T 29-03-2018 IPR032256 Domain of unknown function DUF4829 HVS_RS10690 d401df316b1f489331f754049fb94298 319 Gene3D G3DSA:3.40.50.1820 1 318 1.0E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS10690 d401df316b1f489331f754049fb94298 319 SUPERFAMILY SSF53474 5 315 1.4E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold HVS_RS10690 d401df316b1f489331f754049fb94298 319 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 307 4.7E-117 T 29-03-2018 IPR008391 Acetyl xylan esterase HVS_RS09185 e315ad8b35e2ba854f5fdd88dc6d65b6 88 Pfam PF08483 IstB-like ATP binding N-terminal 25 49 3.6E-9 T 29-03-2018 IPR013690 IstB-like ATP binding N-terminal HVS_RS14185 db5fd89a620ac0f7e3ce9f6c5c8e9abb 153 Pfam PF13401 AAA domain 10 57 4.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS14185 db5fd89a620ac0f7e3ce9f6c5c8e9abb 153 SUPERFAMILY SSF52540 5 147 2.58E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS04660 85deab5fc55d9090ec810922128f9d56 411 Pfam PF14319 Transposase zinc-binding domain 32 104 1.4E-17 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS04660 85deab5fc55d9090ec810922128f9d56 411 Pfam PF04986 Putative transposase 104 265 2.4E-21 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS05510 a6d569b6237724993aea6476fd43e576 455 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 36 423 2.5E-104 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 HVS_RS05510 a6d569b6237724993aea6476fd43e576 455 Pfam PF02386 Cation transport protein 21 442 6.4E-51 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HVS_RS02235 2df1ac2b047227c8dd01684b2ca8944b 65 Pfam PF11213 Protein of unknown function (DUF3006) 3 64 6.8E-24 T 29-03-2018 IPR021377 Protein of unknown function DUF3006 HVS_RS09985 c1ff70a4b9c2153429b2e093f1820cf1 185 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 26 3.8E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS09985 c1ff70a4b9c2153429b2e093f1820cf1 185 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 28 1.6E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site HVS_RS06560 3fa2dcdfd737168138d97364c15179c8 97 Pfam PF04232 Stage V sporulation protein S (SpoVS) 4 83 3.0E-18 T 29-03-2018 IPR007347 Sporulation stage V, protein S HVS_RS10205 b348265ba1cf121838f640e2ce6aa71b 168 Pfam PF03748 Flagellar basal body-associated protein FliL 63 168 3.0E-9 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 HVS_RS03975 2e16fa1e0f6eec7e76f13005a66a62fd 424 SUPERFAMILY SSF51294 165 300 6.41E-26 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03975 2e16fa1e0f6eec7e76f13005a66a62fd 424 Pfam PF07591 Pretoxin HINT domain 171 300 2.0E-28 T 29-03-2018 HVS_RS03975 2e16fa1e0f6eec7e76f13005a66a62fd 424 Gene3D G3DSA:2.170.16.10 161 377 2.4E-38 T 29-03-2018 HVS_RS03975 2e16fa1e0f6eec7e76f13005a66a62fd 424 SMART SM00306 163 257 2.0E-11 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS03975 2e16fa1e0f6eec7e76f13005a66a62fd 424 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 276 300 9.7E-5 T 29-03-2018 IPR030934 Intein C-terminal splicing region HVS_RS12760 d78a8570ff92e47664baebdc22475225 463 Gene3D G3DSA:1.20.1250.20 18 438 5.1E-9 T 29-03-2018 HVS_RS12760 d78a8570ff92e47664baebdc22475225 463 Pfam PF12698 ABC-2 family transporter protein 35 431 6.1E-25 T 29-03-2018 HVS_RS11280 ccf00a2baccba7483d9bc1ada0a63513 145 Pfam PF13490 Putative zinc-finger 10 37 3.6E-5 T 29-03-2018 IPR027383 Putative zinc-finger HVS_RS03935 fec6873d68f0424d0ff23cbc8911977f 89 Pfam PF15649 Restriction endonuclease fold toxin 7 4 73 6.5E-19 T 29-03-2018 IPR028903 Tox-REase-7 domain HVS_RS15465 4df183344916f23a264867854313e0f6 422 SUPERFAMILY SSF55797 75 194 6.8E-5 T 29-03-2018 IPR014044 CAP domain HVS_RS15465 4df183344916f23a264867854313e0f6 422 Gene3D G3DSA:1.10.1330.10 354 422 1.6E-8 T 29-03-2018 HVS_RS15465 4df183344916f23a264867854313e0f6 422 Pfam PF00404 Dockerin type I repeat 361 381 8.7E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS15465 4df183344916f23a264867854313e0f6 422 ProSitePatterns PS00018 EF-hand calcium-binding domain. 393 405 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site HVS_RS15465 4df183344916f23a264867854313e0f6 422 SUPERFAMILY SSF63446 357 421 9.81E-18 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS07610 6a226f223c413d925dce8cc2818701d8 197 SUPERFAMILY SSF52218 3 193 6.01E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS07610 6a226f223c413d925dce8cc2818701d8 197 Gene3D G3DSA:3.40.50.360 2 197 5.3E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain HVS_RS07610 6a226f223c413d925dce8cc2818701d8 197 Pfam PF03358 NADPH-dependent FMN reductase 3 154 3.4E-33 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HVS_RS03125 97be4b2d250dc4c6adfc63d079b434cb 128 Pfam PF05717 IS66 Orf2 like protein 21 115 1.4E-32 T 29-03-2018 IPR008878 Transposase IS66, Orf2 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 SUPERFAMILY SSF50615 2 74 3.14E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 SUPERFAMILY SSF47917 347 462 9.16E-50 T 29-03-2018 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 Gene3D G3DSA:3.40.50.300 76 349 8.6E-90 T 29-03-2018 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 460 7.0E-236 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 Gene3D G3DSA:1.10.1140.10 350 460 1.8E-40 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 335 344 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 SUPERFAMILY SSF52540 77 349 3.35E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 SMART SM00382 143 328 2.3E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 Gene3D G3DSA:2.40.10.170 1 75 3.0E-25 T 29-03-2018 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 344 3.1E-66 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 462 54.246 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 HVS_RS03655 b0be69c4f0e13389403b7d565dd1ce04 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 73 2.7E-18 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HVS_RS03340 935537c3064dbe019c3b108dd71105ea 222 SUPERFAMILY SSF47240 53 208 2.16E-28 T 29-03-2018 IPR009078 Ferritin-like superfamily HVS_RS03340 935537c3064dbe019c3b108dd71105ea 222 Pfam PF02915 Rubrerythrin 59 204 1.7E-18 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 HVS_RS03340 935537c3064dbe019c3b108dd71105ea 222 Gene3D G3DSA:1.20.1260.10 54 208 3.6E-25 T 29-03-2018 IPR012347 Ferritin-related HVS_RS07875 b52535eddadabae566475382ba32d07c 399 Gene3D G3DSA:3.30.457.10 132 244 6.1E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07875 b52535eddadabae566475382ba32d07c 399 Gene3D G3DSA:3.30.457.10 64 131 1.0E-20 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07875 b52535eddadabae566475382ba32d07c 399 Gene3D G3DSA:3.30.457.10 19 63 3.4E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07875 b52535eddadabae566475382ba32d07c 399 SUPERFAMILY SSF55383 55 143 3.27E-22 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07875 b52535eddadabae566475382ba32d07c 399 Pfam PF07833 Copper amine oxidase N-terminal domain 52 149 2.7E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS07875 b52535eddadabae566475382ba32d07c 399 Pfam PF14343 PrcB C-terminal 203 260 7.0E-14 T 29-03-2018 IPR025748 PrcB C-terminal domain HVS_RS02300 93577f9a241329262be4cfb8705d2f12 329 SUPERFAMILY SSF161098 79 313 2.88E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS02300 93577f9a241329262be4cfb8705d2f12 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 316 3.0E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS02300 93577f9a241329262be4cfb8705d2f12 329 Gene3D G3DSA:1.10.3720.10 33 328 3.6E-36 T 29-03-2018 HVS_RS10655 0e2e4f783f5aa0b92211bc367ca81b92 204 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 5 201 1.9E-53 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HVS_RS10655 0e2e4f783f5aa0b92211bc367ca81b92 204 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 200 19.785 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HVS_RS10655 0e2e4f783f5aa0b92211bc367ca81b92 204 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 191 1.0E-51 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HVS_RS10655 0e2e4f783f5aa0b92211bc367ca81b92 204 SMART SM01207 10 192 7.6E-75 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 HVS_RS00025 f96a8b52046cef3c1fd94e59bb23c585 94 Pfam PF04025 Domain of unknown function (DUF370) 2 80 5.9E-12 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 HVS_RS10525 f0e5a8312045f241a6b292a375e098ba 116 SUPERFAMILY SSF55315 3 99 4.99E-24 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS10525 f0e5a8312045f241a6b292a375e098ba 116 Gene3D G3DSA:3.30.1330.30 1 99 2.5E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like HVS_RS10525 f0e5a8312045f241a6b292a375e098ba 116 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 94 1.4E-12 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 HVS_RS12405 2a0e83247481e3f4209d4093fee0e788 153 Pfam PF13401 AAA domain 10 57 2.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS12405 2a0e83247481e3f4209d4093fee0e788 153 SUPERFAMILY SSF52540 5 146 3.74E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03185 707062aca0428f848c9074da30122133 258 Pfam PF02698 DUF218 domain 104 247 1.1E-31 T 29-03-2018 IPR003848 Domain of unknown function DUF218 HVS_RS03185 707062aca0428f848c9074da30122133 258 Gene3D G3DSA:3.40.50.620 93 237 1.3E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS03375 5576a286146e78953d13047eb8c19b19 370 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 3.1E-21 T 29-03-2018 IPR001727 Gdt1 family HVS_RS03375 5576a286146e78953d13047eb8c19b19 370 Pfam PF01169 Uncharacterized protein family UPF0016 104 178 1.1E-15 T 29-03-2018 IPR001727 Gdt1 family HVS_RS07040 51ad7d2a16eb90ce67d10974cd16e1d8 254 Pfam PF01976 Protein of unknown function DUF116 96 248 1.7E-47 T 29-03-2018 IPR002829 Protein of unknown function DUF116 HVS_RS07040 51ad7d2a16eb90ce67d10974cd16e1d8 254 PIRSF PIRSF006594 9 254 6.5E-46 T 29-03-2018 IPR002829 Protein of unknown function DUF116 HVS_RS00725 26693f1e9b914b8223ee850048177ccf 187 Gene3D G3DSA:3.40.30.10 7 125 0.0013 T 29-03-2018 HVS_RS00725 26693f1e9b914b8223ee850048177ccf 187 Pfam PF10865 Domain of unknown function (DUF2703) 32 146 3.3E-37 T 29-03-2018 IPR021219 Protein of unknown function DUF2703 HVS_RS07540 ffe67386b7c9749bd255e3fe148b27fe 181 SUPERFAMILY SSF81301 5 125 6.78E-15 T 29-03-2018 HVS_RS07540 ffe67386b7c9749bd255e3fe148b27fe 181 Pfam PF01909 Nucleotidyltransferase domain 18 80 4.1E-6 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 HVS_RS07540 ffe67386b7c9749bd255e3fe148b27fe 181 Gene3D G3DSA:3.30.460.10 3 134 1.1E-15 T 29-03-2018 HVS_RS07220 f21d8d77ef84d30f6d3b874464ae6b7b 246 Pfam PF06541 Putative ABC-transporter type IV 7 167 1.1E-46 T 29-03-2018 IPR010540 Putative ABC-transporter type IV CmpB/TMEM229 HVS_RS03315 c8e717af77c1e0b1f125b006d189c2f1 106 Pfam PF02325 YGGT family 13 88 1.3E-5 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 HVS_RS03160 a1b77ab51152e50aa395c1b643be20f7 399 SUPERFAMILY SSF51338 356 393 1.19E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS03160 a1b77ab51152e50aa395c1b643be20f7 399 SUPERFAMILY SSF51338 2 61 1.19E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS03160 a1b77ab51152e50aa395c1b643be20f7 399 Gene3D G3DSA:3.20.20.140 68 355 8.7E-38 T 29-03-2018 HVS_RS03160 a1b77ab51152e50aa395c1b643be20f7 399 Gene3D G3DSA:2.30.40.10 1 67 2.6E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HVS_RS03160 a1b77ab51152e50aa395c1b643be20f7 399 SUPERFAMILY SSF51556 60 357 3.53E-51 T 29-03-2018 IPR032466 Metal-dependent hydrolase HVS_RS03160 a1b77ab51152e50aa395c1b643be20f7 399 Pfam PF01979 Amidohydrolase family 227 390 3.2E-16 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 HVS_RS08490 a4f5521e14d1f84f8e52ef0cdc890030 239 Gene3D G3DSA:2.40.50.110 95 188 2.6E-5 T 29-03-2018 HVS_RS08490 a4f5521e14d1f84f8e52ef0cdc890030 239 Pfam PF08239 Bacterial SH3 domain 147 186 8.8E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type HVS_RS13205 9bb25c5cb7d43681822ea90e96c6ea16 440 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 37 385 4.8E-95 T 29-03-2018 IPR006427 Phage portal protein, HK97 HVS_RS13205 9bb25c5cb7d43681822ea90e96c6ea16 440 Pfam PF04860 Phage portal protein 46 380 1.5E-119 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein HVS_RS01760 86109a4d9accb5cbcc0d00ce5f8af8b1 517 Pfam PF00395 S-layer homology domain 385 426 1.6E-8 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01760 86109a4d9accb5cbcc0d00ce5f8af8b1 517 Pfam PF00395 S-layer homology domain 309 345 1.8E-9 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS01700 417ff0f86a3f97a837bf2da7cf0136de 703 Gene3D G3DSA:3.40.50.410 68 538 6.8E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A HVS_RS08045 08413fecab3150a64a217d4058d90497 149 Pfam PF01592 NifU-like N terminal domain 1 122 5.8E-50 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 HVS_RS08045 08413fecab3150a64a217d4058d90497 149 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 121 3.4E-67 T 29-03-2018 IPR017787 NIF system FeS cluster assembly, NifU-like HVS_RS08045 08413fecab3150a64a217d4058d90497 149 SUPERFAMILY SSF82649 4 126 2.38E-47 T 29-03-2018 HVS_RS08045 08413fecab3150a64a217d4058d90497 149 Gene3D G3DSA:3.90.1010.10 1 148 1.8E-56 T 29-03-2018 HVS_RS03740 be3548945d6c31614b68efd502d275c6 134 Pfam PF04138 GtrA-like protein 25 133 5.1E-8 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 HVS_RS15180 01ab797370af6aa18fdedcf6b3c1fbe3 129 Pfam PF13581 Histidine kinase-like ATPase domain 15 122 2.4E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS08970 9dad4675e387e485f6ceef27214ffe45 548 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 242 545 3.3E-76 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 HVS_RS08970 9dad4675e387e485f6ceef27214ffe45 548 Pfam PF08486 Stage II sporulation protein 239 328 2.2E-26 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Gene3D G3DSA:3.30.420.40 290 398 1.1E-6 T 29-03-2018 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 905 1223 1.7E-59 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Gene3D G3DSA:3.30.420.40 98 239 6.4E-30 T 29-03-2018 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Gene3D G3DSA:3.30.420.40 416 561 5.9E-33 T 29-03-2018 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 671 890 1.0E-84 T 29-03-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 SUPERFAMILY SSF53067 7 255 8.82E-55 T 29-03-2018 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 SUPERFAMILY SSF53067 321 576 1.07E-51 T 29-03-2018 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 8 255 7.4E-18 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 322 576 6.3E-35 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 HVS_RS11145 fe6be2565735c172fa675730ebbfc048 1420 Gene3D G3DSA:3.30.420.40 3 69 0.012 T 29-03-2018 HVS_RS06195 94c256b72a7ca4128191c3bb50f7728f 145 Gene3D G3DSA:2.10.109.10 2 101 3.7E-14 T 29-03-2018 HVS_RS06195 94c256b72a7ca4128191c3bb50f7728f 145 SUPERFAMILY SSF51306 13 136 1.44E-9 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS06195 94c256b72a7ca4128191c3bb50f7728f 145 Pfam PF00717 Peptidase S24-like 14 78 9.3E-6 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C HVS_RS03005 2e22932abe50dd0426ce8b0148b0e59b 292 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HVS_RS03005 2e22932abe50dd0426ce8b0148b0e59b 292 SUPERFAMILY SSF52540 5 223 3.18E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS03005 2e22932abe50dd0426ce8b0148b0e59b 292 SMART SM00382 28 208 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain HVS_RS03005 2e22932abe50dd0426ce8b0148b0e59b 292 Gene3D G3DSA:3.40.50.300 1 253 1.0E-66 T 29-03-2018 HVS_RS03005 2e22932abe50dd0426ce8b0148b0e59b 292 Pfam PF00005 ABC transporter 22 162 1.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HVS_RS09755 d73a8832883bb17bb79f2fed3c681969 733 SUPERFAMILY SSF49785 588 732 1.16E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09755 d73a8832883bb17bb79f2fed3c681969 733 Gene3D G3DSA:2.60.120.260 587 733 9.9E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS09755 d73a8832883bb17bb79f2fed3c681969 733 Pfam PF12791 Anti-sigma factor N-terminus 8 47 1.6E-8 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal HVS_RS01555 0d525353bd9bd298b67897b6955aa247 363 Gene3D G3DSA:1.20.1380.10 136 229 5.8E-16 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 HVS_RS09610 cf2e250b4db4c3cd12196037173c947a 211 Gene3D G3DSA:3.10.196.10 91 209 2.5E-14 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09610 cf2e250b4db4c3cd12196037173c947a 211 PIRSF PIRSF037984 6 211 3.5E-57 T 29-03-2018 IPR017342 S-adenosyl-L-methionine dependent methionine synthase, predicted HVS_RS09610 cf2e250b4db4c3cd12196037173c947a 211 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 98 203 2.4E-5 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS09610 cf2e250b4db4c3cd12196037173c947a 211 SUPERFAMILY SSF56507 25 207 1.96E-34 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 HVS_RS04680 14dd97d810971c1c555f4692900272ec 533 Pfam PF03354 Phage Terminase 51 513 2.7E-78 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type HVS_RS00950 c4d9c230754e953b05830583b3fce799 190 SUPERFAMILY SSF52309 69 176 2.96E-9 T 29-03-2018 HVS_RS04510 5cc537c00ca2760dbb3cc05ca7fd516a 317 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 58 316 2.1E-86 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS04670 228d459b5d7516cee9940f0de037a934 58 Pfam PF16468 Domain of unknown function (DUF5049) 1 57 6.5E-34 T 29-03-2018 IPR032488 Protein of unknown function DUF5049 HVS_RS09795 84664f87920595a8addbba251e392629 637 Pfam PF01973 Protein of unknown function DUF115 215 386 2.7E-39 T 29-03-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like HVS_RS09795 84664f87920595a8addbba251e392629 637 Gene3D G3DSA:3.90.1480.10 222 520 3.0E-47 T 29-03-2018 HVS_RS14445 45ea1dd49ef74ce329b7de278087e7a2 100 Gene3D G3DSA:3.30.1390.10 24 98 8.7E-8 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HVS_RS14325 78d7f0d3f5d3735beba4f54d5eaeccb1 58 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 55 1.2E-10 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HVS_RS12395 1a07ca17c78201a8daabbad4c3e8e67a 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 20 163 6.6E-53 T 29-03-2018 HVS_RS12395 1a07ca17c78201a8daabbad4c3e8e67a 164 SUPERFAMILY SSF52833 15 163 1.04E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS12395 1a07ca17c78201a8daabbad4c3e8e67a 164 Gene3D G3DSA:3.40.30.10 81 164 3.5E-18 T 29-03-2018 HVS_RS12395 1a07ca17c78201a8daabbad4c3e8e67a 164 PIRSF PIRSF000216 5 164 5.8E-56 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 HVS_RS10095 39cad05f3b91db45d9cc0b66e1cc8563 247 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 215 243 0.003 T 29-03-2018 HVS_RS15535 ddb0e9b4111b09af3a2f244946e5d497 79 Pfam PF11007 Spore coat associated protein JA (CotJA) 34 67 8.6E-17 T 29-03-2018 IPR020256 Spore coat protein CotJA HVS_RS13255 197350253e75a4ff55f2da69c623e2fc 183 Pfam PF05119 Phage terminase, small subunit 71 146 1.3E-6 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family HVS_RS08005 093fde4f30b6b1624cb18b95f0010fa3 322 Gene3D G3DSA:1.10.443.10 133 308 2.9E-44 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS08005 093fde4f30b6b1624cb18b95f0010fa3 322 Pfam PF00589 Phage integrase family 133 300 2.1E-41 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HVS_RS08005 093fde4f30b6b1624cb18b95f0010fa3 322 SUPERFAMILY SSF56349 11 306 4.71E-50 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HVS_RS08005 093fde4f30b6b1624cb18b95f0010fa3 322 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 8 108 9.9E-9 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HVS_RS08005 093fde4f30b6b1624cb18b95f0010fa3 322 Gene3D G3DSA:1.10.150.130 5 132 6.2E-20 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal HVS_RS10140 a21ab2a2cc00cd507bfc3a75b55c2161 220 Pfam PF01339 CheB methylesterase 31 212 1.8E-60 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS10140 a21ab2a2cc00cd507bfc3a75b55c2161 220 SUPERFAMILY SSF52738 27 216 3.01E-64 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS10140 a21ab2a2cc00cd507bfc3a75b55c2161 220 Gene3D G3DSA:3.40.50.180 20 220 4.8E-75 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 HVS_RS15545 f3c4d0ffb82e824e5627ac9997198fc7 151 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 122 4.3E-28 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain HVS_RS15545 f3c4d0ffb82e824e5627ac9997198fc7 151 PIRSF PIRSF006019 1 150 3.7E-56 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 HVS_RS15545 f3c4d0ffb82e824e5627ac9997198fc7 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 77 112 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HVS_RS15545 f3c4d0ffb82e824e5627ac9997198fc7 151 Gene3D G3DSA:3.40.140.10 2 150 2.0E-40 T 29-03-2018 HVS_RS15545 f3c4d0ffb82e824e5627ac9997198fc7 151 SUPERFAMILY SSF53927 6 145 5.69E-41 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 HVS_RS00165 d99c676140dd911727f8da780446a5f9 87 PIRSF PIRSF037257 1 86 4.7E-31 T 29-03-2018 IPR009366 Protein Veg GO:0042710 HVS_RS00165 d99c676140dd911727f8da780446a5f9 87 Pfam PF06257 Biofilm formation stimulator VEG 5 75 2.0E-30 T 29-03-2018 IPR009366 Protein Veg GO:0042710 HVS_RS00165 d99c676140dd911727f8da780446a5f9 87 Gene3D G3DSA:2.30.30.100 3 77 1.5E-29 T 29-03-2018 HVS_RS01710 ec27e523e56d6bea764b549533650799 422 Pfam PF01610 Transposase 292 412 1.5E-14 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS01710 ec27e523e56d6bea764b549533650799 422 Pfam PF01610 Transposase 4 110 4.5E-8 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HVS_RS01710 ec27e523e56d6bea764b549533650799 422 Gene3D G3DSA:1.10.10.60 148 207 4.3E-9 T 29-03-2018 HVS_RS11865 3fb883ee0656c33c16368f5e0d9b3458 325 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 166 2.5E-28 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase HVS_RS07525 5a7844166745ee827d233cdf1a97d761 98 Gene3D G3DSA:2.30.30.140 2 65 5.5E-4 T 29-03-2018 HVS_RS08275 d473fc13b4401181c8944613f80e6a32 751 Pfam PF02687 FtsX-like permease family 289 373 6.1E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS00715 3cec31a2103faad3d068df98a3ab0007 338 Gene3D G3DSA:1.20.1250.20 150 338 4.2E-6 T 29-03-2018 HVS_RS00715 3cec31a2103faad3d068df98a3ab0007 338 Pfam PF03773 Predicted permease 45 331 4.6E-68 T 29-03-2018 IPR005524 Predicted permease DUF318 HVS_RS02305 6af3facf0c6ffea2fde7b1bda7fcf98f 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 295 4.7E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS02305 6af3facf0c6ffea2fde7b1bda7fcf98f 304 SUPERFAMILY SSF161098 16 303 3.66E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HVS_RS02305 6af3facf0c6ffea2fde7b1bda7fcf98f 304 Gene3D G3DSA:1.10.3720.10 16 295 9.5E-38 T 29-03-2018 HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 Gene3D G3DSA:3.40.50.2300 1 161 1.4E-46 T 29-03-2018 HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 152 4.4E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 SMART SM00226 2 155 1.8E-36 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 SUPERFAMILY SSF52788 1 156 1.7E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.6E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 2.6E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HVS_RS15560 a9d7216faea3718d16fa366d487720b9 161 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 127 142 2.6E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HVS_RS03225 da3269d42c741c39a0217b8a923fb3a2 379 Pfam PF02321 Outer membrane efflux protein 92 193 5.6E-10 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HVS_RS03225 da3269d42c741c39a0217b8a923fb3a2 379 Pfam PF02321 Outer membrane efflux protein 280 376 6.7E-11 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 HVS_RS03225 da3269d42c741c39a0217b8a923fb3a2 379 Gene3D G3DSA:1.20.1600.10 30 377 4.1E-31 T 29-03-2018 HVS_RS03225 da3269d42c741c39a0217b8a923fb3a2 379 SUPERFAMILY SSF56954 4 374 1.28E-28 T 29-03-2018 HVS_RS14470 c86d5738c0420e953a7acb0968d36934 300 PIRSF PIRSF006483 3 299 7.6E-85 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT HVS_RS14470 c86d5738c0420e953a7acb0968d36934 300 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 239 293 5.5E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 HVS_RS14470 c86d5738c0420e953a7acb0968d36934 300 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 12 233 5.0E-61 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT HVS_RS08655 8841d1f12cbbbf09f31ad69eb5aac935 209 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 14 205 2.8E-31 T 29-03-2018 IPR014245 Sporulation stage III, protein AF HVS_RS08655 8841d1f12cbbbf09f31ad69eb5aac935 209 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 103 2.9E-19 T 29-03-2018 IPR014245 Sporulation stage III, protein AF HVS_RS13730 70730f317ec1561132c22c1269f4d8ef 406 Pfam PF00872 Transposase, Mutator family 9 377 2.2E-144 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HVS_RS12390 73df5c0cd148ccd5ae46b2b36a8eaf9c 188 SUPERFAMILY SSF55874 7 142 1.44E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS12390 73df5c0cd148ccd5ae46b2b36a8eaf9c 188 Gene3D G3DSA:3.30.565.10 2 109 9.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS12390 73df5c0cd148ccd5ae46b2b36a8eaf9c 188 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 8 102 2.5E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain HVS_RS04025 f5bbd7fb19e5311fb2a052fd68aba41c 96 Pfam PF15580 Immunity protein 53 4 94 1.4E-34 T 29-03-2018 IPR028228 Immunity protein 53 HVS_RS07345 faef432804d279da84db19913d43de0a 153 Gene3D G3DSA:3.90.20.10 19 128 0.001 T 29-03-2018 HVS_RS14025 24a4c988299dfecdffadb34edc5b1f87 213 Gene3D G3DSA:3.90.20.10 4 205 7.0E-6 T 29-03-2018 HVS_RS14025 24a4c988299dfecdffadb34edc5b1f87 213 SUPERFAMILY SSF46579 98 186 2.46E-5 T 29-03-2018 HVS_RS02070 0a59863256e99e658d05d88a7476a7fb 259 SUPERFAMILY SSF69318 17 118 1.96E-5 T 29-03-2018 HVS_RS09160 ab840c4871640bfd2d8ecd7212128944 297 Pfam PF08902 Domain of unknown function (DUF1848) 22 288 7.5E-32 T 29-03-2018 IPR014998 Protein of unknown function DUF1848 HVS_RS12585 9c4928c432073c10ffe4e6f40123579a 219 Pfam PF01171 PP-loop family 8 187 5.6E-17 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 HVS_RS12585 9c4928c432073c10ffe4e6f40123579a 219 Gene3D G3DSA:3.40.50.620 1 215 7.5E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS12585 9c4928c432073c10ffe4e6f40123579a 219 PIRSF PIRSF004976 1 217 1.8E-53 T 29-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 HVS_RS12585 9c4928c432073c10ffe4e6f40123579a 219 SUPERFAMILY SSF52402 1 196 4.71E-41 T 29-03-2018 HVS_RS08070 2607ae6fa05c18584c52bd1d3536622f 124 SUPERFAMILY SSF56276 3 116 1.96E-47 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HVS_RS08070 2607ae6fa05c18584c52bd1d3536622f 124 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 33.5 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS08070 2607ae6fa05c18584c52bd1d3536622f 124 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 1.9E-42 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS08070 2607ae6fa05c18584c52bd1d3536622f 124 Gene3D G3DSA:3.60.90.10 1 123 8.9E-47 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 HVS_RS08070 2607ae6fa05c18584c52bd1d3536622f 124 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 4.8E-47 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 HVS_RS11645 129597c306de85ac0d748755d1123373 103 Pfam PF10719 Late competence development protein ComFB 15 99 1.7E-17 T 29-03-2018 IPR019657 Late competence development protein ComFB HVS_RS15540 2966884fdb7500caa65334d252a74b9c 377 ProSitePatterns PS01348 MraY family signature 2. 162 173 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 HVS_RS15540 2966884fdb7500caa65334d252a74b9c 377 Pfam PF00953 Glycosyl transferase family 4 84 242 1.1E-45 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 HVS_RS12385 bad49cf52c2cb224b5d519ee9edd550e 123 SUPERFAMILY SSF52833 26 119 2.98E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold HVS_RS12385 bad49cf52c2cb224b5d519ee9edd550e 123 Gene3D G3DSA:3.40.30.10 23 123 2.7E-16 T 29-03-2018 HVS_RS12545 9d21fe9778ba7cbf6c5e902ea455a8e7 497 Pfam PF07556 Protein of unknown function (DUF1538) 272 482 1.8E-62 T 29-03-2018 IPR011435 Protein of unknown function DUF1538 HVS_RS12545 9d21fe9778ba7cbf6c5e902ea455a8e7 497 Pfam PF07556 Protein of unknown function (DUF1538) 18 229 3.9E-55 T 29-03-2018 IPR011435 Protein of unknown function DUF1538 HVS_RS00105 19ae26361780875ce14344132e6066ea 88 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 83 2.1E-18 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA HVS_RS11245 36b2166354d620f5898cdd9773bd1da1 49 SUPERFAMILY SSF140500 2 43 5.89E-7 T 29-03-2018 HVS_RS11245 36b2166354d620f5898cdd9773bd1da1 49 Pfam PF09388 Spo0E like sporulation regulatory protein 1 38 2.0E-7 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 HVS_RS01455 629ab49d20789c9192dad664ac3cb0cf 356 SUPERFAMILY SSF53756 16 354 2.88E-12 T 29-03-2018 HVS_RS01455 629ab49d20789c9192dad664ac3cb0cf 356 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 1 294 2.9E-68 T 29-03-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase HVS_RS01455 629ab49d20789c9192dad664ac3cb0cf 356 Gene3D G3DSA:3.40.50.2000 165 349 9.1E-17 T 29-03-2018 HVS_RS01605 cacc5d08ff5379c8fa23cdcda9c336a2 295 SUPERFAMILY SSF81345 10 271 2.35E-26 T 29-03-2018 IPR029022 ABC transporter, BtuC-like HVS_RS01605 cacc5d08ff5379c8fa23cdcda9c336a2 295 Pfam PF00950 ABC 3 transport family 10 275 2.1E-45 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 HVS_RS01605 cacc5d08ff5379c8fa23cdcda9c336a2 295 Gene3D G3DSA:1.10.3470.10 5 283 4.0E-26 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like HVS_RS09635 c5e9996597286da361235b018d2c3aaa 152 Pfam PF04472 Cell division protein SepF 63 134 2.7E-30 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 HVS_RS09635 c5e9996597286da361235b018d2c3aaa 152 Hamap MF_01197 Cell division protein SepF [sepF]. 2 142 19.51 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 HVS_RS00355 62a3cd26268cf24db535eb7cb14bfc25 297 Pfam PF02666 Phosphatidylserine decarboxylase 84 286 4.3E-44 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 HVS_RS13320 88170410a910534412d7f404976b05c9 309 Gene3D G3DSA:3.40.50.300 154 224 0.0012 T 29-03-2018 HVS_RS11575 521aa7808dc17cccbd7a5d43bb19fd87 273 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 4 171 2.7E-59 T 29-03-2018 IPR018768 Domain of unknown function DUF2344 HVS_RS11575 521aa7808dc17cccbd7a5d43bb19fd87 273 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 4 166 3.9E-56 T 29-03-2018 IPR018768 Domain of unknown function DUF2344 HVS_RS11875 e035ca75a0241d49bd27065123afaaab 960 Gene3D G3DSA:2.60.120.260 230 416 8.6E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS11875 e035ca75a0241d49bd27065123afaaab 960 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 678 753 9.2E-15 T 29-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 HVS_RS11875 e035ca75a0241d49bd27065123afaaab 960 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 864 957 3.9E-8 T 29-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 HVS_RS11875 e035ca75a0241d49bd27065123afaaab 960 Gene3D G3DSA:2.60.120.260 23 192 1.7E-18 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS11875 e035ca75a0241d49bd27065123afaaab 960 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 466 603 2.6E-12 T 29-03-2018 HVS_RS02795 bda83c1318e369b68a51b39aa43bc9e0 198 Pfam PF08849 Putative inner membrane protein (DUF1819) 3 185 1.1E-61 T 29-03-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane HVS_RS02795 bda83c1318e369b68a51b39aa43bc9e0 198 Gene3D G3DSA:1.10.3540.10 2 194 1.7E-57 T 29-03-2018 HVS_RS13855 5a1c7e758f4f015e1f2fe5c3cfcc21d0 70 SUPERFAMILY SSF47240 15 60 1.35E-5 T 29-03-2018 IPR009078 Ferritin-like superfamily HVS_RS13855 5a1c7e758f4f015e1f2fe5c3cfcc21d0 70 Gene3D G3DSA:1.20.1260.10 3 62 1.5E-6 T 29-03-2018 IPR012347 Ferritin-related HVS_RS11355 fcbaf0955a641114b253d9fb6dc2b9fa 78 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 72 4.0E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 HVS_RS08150 ebb7685d2b53fdf7b9ba1d0499ad74c3 243 Gene3D G3DSA:2.40.10.220 95 219 2.7E-16 T 29-03-2018 HVS_RS08150 ebb7685d2b53fdf7b9ba1d0499ad74c3 243 SUPERFAMILY SSF141371 95 203 1.51E-12 T 29-03-2018 HVS_RS08150 ebb7685d2b53fdf7b9ba1d0499ad74c3 243 Pfam PF07238 PilZ domain 100 198 4.4E-13 T 29-03-2018 IPR009875 PilZ domain GO:0035438 HVS_RS15855 f4c32016cbae21a211240741fbe91485 132 SUPERFAMILY SSF52206 29 132 3.4E-27 T 29-03-2018 IPR015032 MTH538 TIR-like domain HVS_RS15855 f4c32016cbae21a211240741fbe91485 132 Gene3D G3DSA:3.40.50.9200 23 132 1.6E-16 T 29-03-2018 HVS_RS15855 f4c32016cbae21a211240741fbe91485 132 Pfam PF08937 MTH538 TIR-like domain (DUF1863) 3 108 1.6E-12 T 29-03-2018 IPR015032 MTH538 TIR-like domain HVS_RS13385 818f65c832039dca5f5b746388f5b08d 162 Pfam PF06695 Putative small multi-drug export protein 28 149 1.8E-41 T 29-03-2018 IPR009577 Putative small multi-drug export HVS_RS09615 e8ec6b79938c49f9e1bcefbfcfee8367 61 Gene3D G3DSA:1.20.1260.10 1 61 4.0E-10 T 29-03-2018 IPR012347 Ferritin-related HVS_RS09615 e8ec6b79938c49f9e1bcefbfcfee8367 61 Pfam PF07875 Coat F domain 18 58 1.4E-5 T 29-03-2018 IPR012851 Spore coat protein CotF-like HVS_RS01340 5ab6d840ef86fba0a6e1cafa936d9941 124 Gene3D G3DSA:3.90.550.10 38 116 1.5E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS14415 0a0bd8d11fd772c74e6b51d50df45096 311 Pfam PF01963 TraB family 42 304 3.9E-59 T 29-03-2018 IPR002816 Pheromone shutdown, TraB HVS_RS01360 bfa5e5d94ad059a422874c0d25faf313 219 Pfam PF00156 Phosphoribosyl transferase domain 86 215 6.1E-12 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 HVS_RS01360 bfa5e5d94ad059a422874c0d25faf313 219 Gene3D G3DSA:3.40.50.2020 59 218 4.6E-31 T 29-03-2018 HVS_RS01360 bfa5e5d94ad059a422874c0d25faf313 219 SUPERFAMILY SSF53271 55 214 4.33E-32 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like HVS_RS05105 5eb865f72e27903df7245e95a90960eb 348 SUPERFAMILY SSF52151 5 77 1.26E-39 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HVS_RS05105 5eb865f72e27903df7245e95a90960eb 348 SUPERFAMILY SSF52151 142 344 1.26E-39 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HVS_RS05105 5eb865f72e27903df7245e95a90960eb 348 Pfam PF01734 Patatin-like phospholipase 10 262 1.2E-33 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 HVS_RS05105 5eb865f72e27903df7245e95a90960eb 348 Gene3D G3DSA:3.40.1090.10 2 267 1.4E-40 T 29-03-2018 HVS_RS11330 9a115642883e676bbeab0acd5d8afa51 389 Gene3D G3DSA:2.115.10.10 113 372 0.0014 T 29-03-2018 HVS_RS06390 3109f79eb0f5694bbf80b1644baa8904 211 Gene3D G3DSA:3.90.550.10 1 200 4.0E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS06390 3109f79eb0f5694bbf80b1644baa8904 211 SUPERFAMILY SSF53448 3 171 7.72E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases HVS_RS06390 3109f79eb0f5694bbf80b1644baa8904 211 Pfam PF00535 Glycosyl transferase family 2 4 127 4.1E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 HVS_RS11935 722dfd02dbb3f706d16114defde28de6 119 Gene3D G3DSA:3.40.50.620 1 110 1.0E-6 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HVS_RS11935 722dfd02dbb3f706d16114defde28de6 119 SUPERFAMILY SSF52402 2 95 9.21E-5 T 29-03-2018 HVS_RS08645 3c9b7c8bb43986616d2b723b1717f679 217 Pfam PF12685 SpoIIIAH-like protein 6 212 1.4E-41 T 29-03-2018 IPR024232 Stage III sporulation protein AH-like HVS_RS14980 b18cc93b633edfccf6f9a121d765eda3 197 Gene3D G3DSA:3.40.50.150 5 196 3.4E-27 T 29-03-2018 HVS_RS14980 b18cc93b633edfccf6f9a121d765eda3 197 Pfam PF05175 Methyltransferase small domain 27 192 1.8E-46 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 HVS_RS14980 b18cc93b633edfccf6f9a121d765eda3 197 SUPERFAMILY SSF53335 6 195 1.24E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS13210 98c04c471969037fbf9fcdeb685f661f 550 Pfam PF03354 Phage Terminase 66 532 1.1E-76 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type HVS_RS04400 81ab3c3bac1ad28cd98bd57f93f1d485 272 SUPERFAMILY SSF110710 24 252 6.8E-45 T 29-03-2018 HVS_RS04400 81ab3c3bac1ad28cd98bd57f93f1d485 272 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 54 250 1.2E-35 T 29-03-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 HVS_RS03560 98cdeacb0079fa7c78c5fa1674d6822b 176 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 9 122 4.5E-19 T 29-03-2018 IPR000477 Reverse transcriptase domain HVS_RS03560 98cdeacb0079fa7c78c5fa1674d6822b 176 Gene3D G3DSA:3.30.70.270 2 134 8.7E-14 T 29-03-2018 HVS_RS03560 98cdeacb0079fa7c78c5fa1674d6822b 176 SUPERFAMILY SSF56672 6 119 7.34E-21 T 29-03-2018 HVS_RS11050 f761433f53879124cadd402e81fe5a26 141 SUPERFAMILY SSF158430 2 135 9.29E-19 T 29-03-2018 HVS_RS11050 f761433f53879124cadd402e81fe5a26 141 Pfam PF11155 Domain of unknown function (DUF2935) 13 133 2.5E-15 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 HVS_RS05750 2e408b1a1b248eb8a3ee879e281159c9 406 ProSitePatterns PS01007 Transposases, Mutator family, signature. 235 259 - T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HVS_RS05750 2e408b1a1b248eb8a3ee879e281159c9 406 Pfam PF00872 Transposase, Mutator family 7 381 5.4E-119 T 29-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 HVS_RS05750 2e408b1a1b248eb8a3ee879e281159c9 406 Gene3D G3DSA:1.10.10.10 100 185 0.016 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03200 4b167fbf9d2c711c6b84e215c88a27a4 176 Gene3D G3DSA:2.40.50.120 46 151 6.5E-4 T 29-03-2018 HVS_RS05490 29bbd2d0bde8ae8675ee62c82adee2e5 129 Pfam PF14276 Domain of unknown function (DUF4363) 10 128 2.9E-30 T 29-03-2018 IPR025373 Protein of unknown function DUF4363 HVS_RS04570 725f66e879fd298f3c28e7183b86f7e0 731 Gene3D G3DSA:3.90.260.10 135 261 0.0022 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS04570 725f66e879fd298f3c28e7183b86f7e0 731 SUPERFAMILY SSF54001 107 168 3.76E-17 T 29-03-2018 HVS_RS04570 725f66e879fd298f3c28e7183b86f7e0 731 SUPERFAMILY SSF54001 213 264 3.76E-17 T 29-03-2018 HVS_RS04570 725f66e879fd298f3c28e7183b86f7e0 731 Pfam PF01526 Tn3 transposase DDE domain 367 710 7.1E-83 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 HVS_RS04570 725f66e879fd298f3c28e7183b86f7e0 731 Pfam PF01841 Transglutaminase-like superfamily 95 244 1.2E-17 T 29-03-2018 IPR002931 Transglutaminase-like HVS_RS04335 abf04a204d104b057b39e14c35895d37 444 Pfam PF06782 Uncharacterised protein family (UPF0236) 10 442 5.9E-84 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 29-03-2018 IPR025505 FHIPEP conserved site HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 5 672 2.5E-260 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 6.7E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 6.7E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 6.7E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 6.7E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 6.7E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 6.7E-54 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 PIRSF PIRSF005419 1 674 7.8E-256 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS10160 e3aca3aff8915235535f7a8aa8c69442 674 Pfam PF00771 FHIPEP family 15 664 6.6E-267 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 HVS_RS07910 3c2eaf9c51b30d0e1b37d055feb37d18 201 Gene3D G3DSA:2.60.60.30 19 199 6.1E-54 T 29-03-2018 HVS_RS07910 3c2eaf9c51b30d0e1b37d055feb37d18 201 Pfam PF02342 TerD domain 1 201 6.3E-74 T 29-03-2018 IPR003325 TerD domain GO:0006950 HVS_RS12695 334081b37e2a5cab6c9e7bd7ccd30936 683 Pfam PF13287 Fn3 associated 84 162 3.3E-12 T 29-03-2018 IPR026876 Fn3 associated repeat HVS_RS12695 334081b37e2a5cab6c9e7bd7ccd30936 683 Pfam PF08757 CotH kinase protein 246 579 3.1E-59 T 29-03-2018 IPR014867 Spore coat protein CotH HVS_RS12695 334081b37e2a5cab6c9e7bd7ccd30936 683 Gene3D G3DSA:2.60.40.10 61 160 6.4E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold HVS_RS10385 b54f52cc4e28f79e9e169306340ab007 261 Gene3D G3DSA:1.20.1250.20 65 258 1.9E-5 T 29-03-2018 HVS_RS10385 b54f52cc4e28f79e9e169306340ab007 261 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 5 250 8.0E-40 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 HVS_RS10420 a7a168dbc602a4f556e91d7a80f266e5 130 Pfam PF02687 FtsX-like permease family 31 118 1.6E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS07355 6b1104cf5209ca65659bb82919915e83 239 Pfam PF05949 Bacterial protein of unknown function (DUF881) 91 228 2.9E-34 T 29-03-2018 IPR010273 Protein of unknown function DUF881 HVS_RS05595 dd3b4f3b9d9fd4eae20e9b67540ed15b 275 Gene3D G3DSA:3.40.50.300 49 275 4.5E-14 T 29-03-2018 HVS_RS05595 dd3b4f3b9d9fd4eae20e9b67540ed15b 275 SUPERFAMILY SSF52540 52 274 5.15E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS13345 7b25ba4882980e8d85d702f84a0c06b9 601 Gene3D G3DSA:3.40.50.300 164 580 4.9E-16 T 29-03-2018 HVS_RS13345 7b25ba4882980e8d85d702f84a0c06b9 601 Pfam PF01935 Domain of unknown function DUF87 240 316 5.9E-5 T 29-03-2018 IPR002789 Helicase HerA, central domain HVS_RS13345 7b25ba4882980e8d85d702f84a0c06b9 601 SUPERFAMILY SSF52540 192 593 1.81E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS08665 6647c48dc21a08ebcd83b18cd1e1eb0c 128 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 125 4.7E-20 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family HVS_RS08665 6647c48dc21a08ebcd83b18cd1e1eb0c 128 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 56 2.8E-11 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family HVS_RS08665 6647c48dc21a08ebcd83b18cd1e1eb0c 128 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 127 1.1E-36 T 29-03-2018 IPR014211 Stage III sporulation protein AD HVS_RS15590 3131d06383bc9edd512ca6b3173fe885 208 Pfam PF02677 Uncharacterized BCR, COG1636 26 201 3.5E-67 T 29-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH HVS_RS15205 2ecc530aac1ca3db6810a3b7fcb47100 323 Gene3D G3DSA:3.40.50.1370 112 204 3.5E-4 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HVS_RS08800 afc6be269cf745fe68d16e484c9810d4 338 Pfam PF16199 Radical_SAM C-terminal domain 185 270 5.5E-22 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 HVS_RS08800 afc6be269cf745fe68d16e484c9810d4 338 SUPERFAMILY SSF102114 10 265 1.29E-54 T 29-03-2018 HVS_RS08800 afc6be269cf745fe68d16e484c9810d4 338 Gene3D G3DSA:3.20.20.70 5 321 1.6E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 HVS_RS08800 afc6be269cf745fe68d16e484c9810d4 338 SMART SM00729 7 224 8.2E-37 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HVS_RS08800 afc6be269cf745fe68d16e484c9810d4 338 Pfam PF04055 Radical SAM superfamily 13 178 2.1E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 HVS_RS03105 f3989ef1b90034416cc4366f4e6ac215 341 SUPERFAMILY SSF53098 205 279 8.34E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS03105 f3989ef1b90034416cc4366f4e6ac215 341 SUPERFAMILY SSF53098 40 141 8.34E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS03105 f3989ef1b90034416cc4366f4e6ac215 341 Gene3D G3DSA:3.90.350.10 1 251 3.1E-28 T 29-03-2018 IPR014736 Transposase, Tn5-like, core HVS_RS03105 f3989ef1b90034416cc4366f4e6ac215 341 Pfam PF01609 Transposase DDE domain 3 268 4.1E-16 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 HVS_RS04410 77e86b7ba997f8852b3b7e8ed2c19241 247 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 57 211 1.1E-5 T 29-03-2018 IPR008884 Macrocin-O-methyltransferase HVS_RS09005 bd0390d225cd7a14800051ca9c53960e 448 Gene3D G3DSA:3.40.50.300 125 319 7.9E-14 T 29-03-2018 HVS_RS09005 bd0390d225cd7a14800051ca9c53960e 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 235 299 6.4E-5 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain HVS_RS09005 bd0390d225cd7a14800051ca9c53960e 448 Gene3D G3DSA:3.40.50.720 334 427 0.032 T 29-03-2018 HVS_RS09005 bd0390d225cd7a14800051ca9c53960e 448 SUPERFAMILY SSF52540 129 298 1.14E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS09005 bd0390d225cd7a14800051ca9c53960e 448 Gene3D G3DSA:3.40.50.720 1 124 7.6E-11 T 29-03-2018 HVS_RS08540 48a74fa436c2336ce508d526d8172fb9 322 Gene3D G3DSA:3.30.1380.10 98 278 9.7E-14 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS08540 48a74fa436c2336ce508d526d8172fb9 322 SUPERFAMILY SSF55166 199 283 4.63E-15 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 HVS_RS08540 48a74fa436c2336ce508d526d8172fb9 322 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 212 278 3.6E-16 T 29-03-2018 HVS_RS03605 4481b33cc160b78df502b7a80c3f787a 149 Pfam PF00082 Subtilase family 8 137 6.2E-26 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS03605 4481b33cc160b78df502b7a80c3f787a 149 SUPERFAMILY SSF52743 9 147 2.62E-43 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS03605 4481b33cc160b78df502b7a80c3f787a 149 Gene3D G3DSA:3.40.50.200 3 149 4.0E-42 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HVS_RS11620 4c77835923425067def0ce658765a775 163 Pfam PF04463 Protein of unknown function (DUF523) 17 156 9.9E-45 T 29-03-2018 IPR007553 Domain of unknown function DUF523 HVS_RS00800 db58891f55b310eb4b1ab1cf2e3282c6 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 9.9E-90 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS00750 db58891f55b310eb4b1ab1cf2e3282c6 483 Pfam PF06782 Uncharacterised protein family (UPF0236) 25 476 9.9E-90 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS08155 fe062362b388fe684c2129c730d1f0a6 187 Pfam PF06962 Putative rRNA methylase 49 185 3.0E-54 T 29-03-2018 IPR010719 Putative rRNA methylase HVS_RS08155 fe062362b388fe684c2129c730d1f0a6 187 Gene3D G3DSA:3.40.50.150 2 187 7.2E-24 T 29-03-2018 HVS_RS08155 fe062362b388fe684c2129c730d1f0a6 187 SUPERFAMILY SSF53335 19 160 6.37E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HVS_RS11710 67a9b4cb21f161e4fab591e67febfe97 217 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 6 28 2.4E-4 T 29-03-2018 IPR006530 YD repeat HVS_RS11710 67a9b4cb21f161e4fab591e67febfe97 217 Pfam PF05593 RHS Repeat 6 41 6.3E-7 T 29-03-2018 IPR031325 RHS repeat HVS_RS03245 67aa0595ff71ebadbac37ea69faa8555 142 Pfam PF04519 Polymer-forming cytoskeletal 14 110 3.6E-25 T 29-03-2018 IPR007607 Protein of unknown function DUF583 HVS_RS03245 67aa0595ff71ebadbac37ea69faa8555 142 Gene3D G3DSA:2.160.20.70 2 142 5.2E-5 T 29-03-2018 HVS_RS00360 4bc4e3fc285b41f05eec3d7eb26cf019 299 Pfam PF01040 UbiA prenyltransferase family 49 260 5.1E-10 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 HVS_RS05330 6d9f2e6af10042a008e22dba87a85563 124 Pfam PF06103 Bacterial protein of unknown function (DUF948) 16 84 3.4E-8 T 29-03-2018 IPR009293 Uncharacterised protein family UPF0478 HVS_RS06960 00130054555d9534f029c8b92c3564d5 65 SUPERFAMILY SSF63446 1 64 1.05E-16 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 HVS_RS06960 00130054555d9534f029c8b92c3564d5 65 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 37 56 - T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS06960 00130054555d9534f029c8b92c3564d5 65 Pfam PF00404 Dockerin type I repeat 37 57 1.8E-5 T 29-03-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 HVS_RS08715 ded50df4f628bdba5eca9768e20d671b 270 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 12 94 3.1E-35 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal HVS_RS08715 ded50df4f628bdba5eca9768e20d671b 270 Pfam PF01478 Type IV leader peptidase family 108 224 4.3E-17 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 HVS_RS04915 966e5cb652b83dc5767ac2a94af1b803 402 Pfam PF12698 ABC-2 family transporter protein 19 390 8.8E-30 T 29-03-2018 HVS_RS04915 966e5cb652b83dc5767ac2a94af1b803 402 Gene3D G3DSA:3.40.1710.10 47 223 1.8E-16 T 29-03-2018 HVS_RS05300 5603fc0052e8f10cae7fdbfe4efdf18e 182 Pfam PF02417 Chromate transporter 11 174 3.4E-45 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 HVS_RS13375 8448fefeea7f224fd4f6b4b3e1cf8ea3 153 PIRSF PIRSF019083 1 151 3.4E-43 T 29-03-2018 IPR016747 Phosphotransbutyrylase HVS_RS13375 8448fefeea7f224fd4f6b4b3e1cf8ea3 153 Pfam PF04892 VanZ like family 8 140 7.3E-26 T 29-03-2018 IPR006976 VanZ-like HVS_RS04495 adbd4934c800e4fba35e6294324b0243 128 Pfam PF10990 Protein of unknown function (DUF2809) 26 109 2.7E-27 T 29-03-2018 IPR021257 Protein of unknown function DUF2809 HVS_RS07360 10a3d5c930b6bb3e76e8efde734f91f5 225 Pfam PF05949 Bacterial protein of unknown function (DUF881) 91 217 8.1E-23 T 29-03-2018 IPR010273 Protein of unknown function DUF881 HVS_RS08855 bba5de86e857fb64785c9737def2df39 83 Gene3D G3DSA:1.20.5.170 1 75 1.2E-5 T 29-03-2018 HVS_RS06620 dfe4e8bd349e9976bab8930e4cdd7822 242 Pfam PF07285 Protein of unknown function (DUF1444) 15 207 2.4E-11 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 HVS_RS04475 d5890e992d2bf4b53c28d65886670f51 324 Pfam PF13212 Domain of unknown function (DUF4020) 142 279 6.0E-15 T 29-03-2018 IPR025093 Domain of unknown function DUF4020 HVS_RS07585 4c50495fdd3cb238da5bd858aa1c779e 293 Gene3D G3DSA:2.70.98.10 104 237 0.0012 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 HVS_RS08285 3f21ce321ba80143557a61f9c9576af9 213 Pfam PF01613 Flavin reductase like domain 32 172 2.8E-10 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 HVS_RS08285 3f21ce321ba80143557a61f9c9576af9 213 SUPERFAMILY SSF50475 30 176 1.57E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 HVS_RS08285 3f21ce321ba80143557a61f9c9576af9 213 Gene3D G3DSA:2.30.110.10 25 189 3.7E-23 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 HVS_RS13170 7655febf3f77015469112a75a5a321dc 199 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 1 190 1.5E-31 T 29-03-2018 IPR006490 Phage major tail protein, phi13 family HVS_RS15770 ce62752d2cc949e4849e67bb047ecfcc 73 Pfam PF04070 Domain of unknown function (DUF378) 5 65 6.4E-22 T 29-03-2018 IPR007211 Protein of unknown function DUF378 HVS_RS01060 4d9f4fcb166f5063ef8e9b81d02d777c 58 Pfam PF13333 Integrase core domain 1 46 1.1E-5 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 HVS_RS01060 4d9f4fcb166f5063ef8e9b81d02d777c 58 Gene3D G3DSA:3.30.420.10 1 58 7.7E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 HVS_RS06485 eebd508ee031d236c4253748ac086bda 407 Pfam PF07949 YbbR-like protein 135 205 6.1E-10 T 29-03-2018 IPR012505 YbbR-like HVS_RS06485 eebd508ee031d236c4253748ac086bda 407 Pfam PF07949 YbbR-like protein 224 304 8.0E-11 T 29-03-2018 IPR012505 YbbR-like HVS_RS11275 a2f2076d705dec2f227ed3fdc93a7b87 212 Pfam PF11167 Protein of unknown function (DUF2953) 126 167 5.3E-8 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 HVS_RS04550 303507e3a32f0bc8a46cfb68f527fba5 538 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 58 523 1.4E-184 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS04550 303507e3a32f0bc8a46cfb68f527fba5 538 PIRSF PIRSF005690 43 536 6.5E-176 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS10345 60a02d306453d8c6f628f87a05529953 277 Pfam PF08478 POTRA domain, FtsQ-type 43 123 3.6E-6 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type HVS_RS08720 1f8ccade7b899185a389d11ec2f7ecbd 435 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 76 225 3.7E-10 T 29-03-2018 HVS_RS12710 f4b9f6266e8f1a873b4bccbbaed6fd08 272 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 29 142 9.5E-8 T 29-03-2018 IPR031161 Peptidase family M60 domain HVS_RS07280 4d8afe658c2c9bdbd9ea7304c21a833b 229 SUPERFAMILY SSF52540 9 220 2.32E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS07280 4d8afe658c2c9bdbd9ea7304c21a833b 229 Gene3D G3DSA:3.40.50.300 2 227 4.9E-15 T 29-03-2018 HVS_RS01815 70e15a264c149e785e58aafee9fe4950 230 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 222 4.0E-55 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 HVS_RS00200 770c5fe4a138257dd841222ec0552719 248 Pfam PF04012 PspA/IM30 family 3 217 5.4E-9 T 29-03-2018 IPR007157 PspA/IM30 HVS_RS00200 770c5fe4a138257dd841222ec0552719 248 Gene3D G3DSA:1.10.287.620 28 248 0.0026 T 29-03-2018 HVS_RS13415 9a5f151b9f5ba41146cddef8bf32611a 398 SUPERFAMILY SSF53756 77 387 5.5E-35 T 29-03-2018 HVS_RS13415 9a5f151b9f5ba41146cddef8bf32611a 398 Gene3D G3DSA:3.40.50.2000 167 393 9.5E-27 T 29-03-2018 HVS_RS13415 9a5f151b9f5ba41146cddef8bf32611a 398 Pfam PF00534 Glycosyl transferases group 1 211 368 1.1E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 HVS_RS11135 f8cc6cf9299ddbef320d49f40424ea21 414 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 101 410 1.7E-72 T 29-03-2018 IPR010897 Sporulation stage II, protein P HVS_RS11135 f8cc6cf9299ddbef320d49f40424ea21 414 Gene3D G3DSA:3.40.630.40 206 413 5.9E-9 T 29-03-2018 HVS_RS11135 f8cc6cf9299ddbef320d49f40424ea21 414 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 211 414 6.4E-58 T 29-03-2018 IPR010897 Sporulation stage II, protein P HVS_RS04920 37a2c19f37d35ffc8959c4b805259fd4 398 Gene3D G3DSA:3.40.1710.10 38 222 5.4E-15 T 29-03-2018 HVS_RS04920 37a2c19f37d35ffc8959c4b805259fd4 398 Pfam PF12698 ABC-2 family transporter protein 22 386 1.2E-29 T 29-03-2018 HVS_RS04770 fab0e7b4cf2c8c321af669a841ee937b 83 Pfam PF05717 IS66 Orf2 like protein 5 71 3.0E-20 T 29-03-2018 IPR008878 Transposase IS66, Orf2 HVS_RS13645 c28bd8bca6ae8feffa7fd2ae63a0e47f 302 Pfam PF03787 RAMP superfamily 10 189 2.3E-4 T 29-03-2018 IPR005537 CRISPR type III-associated RAMP protein HVS_RS12530 42ac85a15f1640f364a07050a2b62035 460 PIRSF PIRSF006603 1 454 1.2E-62 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS12530 42ac85a15f1640f364a07050a2b62035 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 419 9.1E-47 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS12530 42ac85a15f1640f364a07050a2b62035 460 Pfam PF01554 MatE 246 405 7.6E-18 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS12530 42ac85a15f1640f364a07050a2b62035 460 Pfam PF01554 MatE 27 185 2.8E-19 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS04665 5b053a2f95bda858d2e7506365b11daa 44 Pfam PF14192 Domain of unknown function (DUF4314) 1 39 4.6E-16 T 29-03-2018 IPR025463 Domain of unknown function DUF4314 HVS_RS00325 485275439f9ff4fecfebe0caeb9263d9 157 Gene3D G3DSA:2.60.120.260 72 146 4.4E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like HVS_RS08640 e9357b0ef130afac977f18a73929e794 138 Pfam PF03780 Asp23 family, cell envelope-related function 17 120 1.8E-41 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 HVS_RS08775 5d216e40bb6bfc83385269c6d11a0a23 319 Pfam PF13490 Putative zinc-finger 4 38 4.3E-9 T 29-03-2018 IPR027383 Putative zinc-finger HVS_RS14150 1560cddb6f31b0a39b23dffa691fbeb5 217 Pfam PF13346 ABC-2 family transporter protein 3 206 5.8E-18 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like HVS_RS03685 2882285a77e124ff891f6c24b204d039 49 Gene3D G3DSA:1.10.10.10 1 45 2.0E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain HVS_RS03685 2882285a77e124ff891f6c24b204d039 49 Pfam PF08279 HTH domain 9 39 2.4E-6 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 HVS_RS07685 d8266254fb56765a10296a3866f4fba3 331 Hamap MF_01562 UPF0365 protein . 2 322 47.911 T 29-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity HVS_RS07685 d8266254fb56765a10296a3866f4fba3 331 Pfam PF12127 SigmaW regulon antibacterial 8 319 1.9E-164 T 29-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity HVS_RS10850 9830157982be2406bf1863acd0336b5f 67 SUPERFAMILY SSF54909 1 59 9.83E-10 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel HVS_RS10850 9830157982be2406bf1863acd0336b5f 67 Pfam PF07876 Stress responsive A/B Barrel Domain 2 60 4.1E-12 T 29-03-2018 IPR013097 Stress responsive alpha-beta barrel HVS_RS10850 9830157982be2406bf1863acd0336b5f 67 Gene3D G3DSA:3.30.70.100 1 62 9.9E-14 T 29-03-2018 HVS_RS13445 78328d2f042941c561f6de73e30d841e 209 Pfam PF02397 Bacterial sugar transferase 6 184 1.3E-62 T 29-03-2018 IPR003362 Bacterial sugar transferase HVS_RS07300 5ff24f2c59f626d5d679356d936b5055 392 Pfam PF07907 YibE/F-like protein 139 379 1.9E-83 T 29-03-2018 IPR012507 YibE/F-like HVS_RS14195 71e6880cdcdd2b35e6f6a2c3cfd527ac 218 Pfam PF02659 Putative manganese efflux pump 37 212 7.3E-9 T 29-03-2018 IPR003810 Putative manganese efflux pump HVS_RS14195 71e6880cdcdd2b35e6f6a2c3cfd527ac 218 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 4 215 1.2E-53 T 29-03-2018 IPR014205 Sporulation protein YtaF HVS_RS04530 f6e96d5695eeea0250c81cdc6b7d9714 424 Pfam PF02687 FtsX-like permease family 326 416 1.2E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS03725 8d997acfec3cabcfea245280851fe89a 88 Pfam PF02583 Metal-sensitive transcriptional repressor 5 84 4.5E-26 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 HVS_RS06915 642b68708b59881e9f8fcd3a1f83201b 241 Pfam PF01863 Protein of unknown function DUF45 20 235 2.1E-63 T 29-03-2018 IPR002725 Protein of unknown function DUF45 HVS_RS10550 49d3c9135662417361dd6ce2d65a8a61 146 Pfam PF03845 Spore germination protein 2 140 7.5E-15 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 HVS_RS08550 f991341d82e103ccacb51e33cd0fad77 143 Pfam PF10776 Protein of unknown function (DUF2600) 2 140 4.2E-50 T 29-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 HVS_RS14050 cdc6f746185889d25fa70e4531c005be 297 Pfam PF01040 UbiA prenyltransferase family 31 264 1.4E-24 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 HVS_RS01365 6d16526533f9a1eed7b75f2f677ebab5 138 Gene3D G3DSA:2.20.28.10 77 119 0.083 T 29-03-2018 HVS_RS01365 6d16526533f9a1eed7b75f2f677ebab5 138 Gene3D G3DSA:2.20.28.10 6 30 0.097 T 29-03-2018 HVS_RS01365 6d16526533f9a1eed7b75f2f677ebab5 138 Gene3D G3DSA:1.10.10.60 31 69 4.8E-4 T 29-03-2018 HVS_RS13350 b1988b1b33bc47852d335a4a19d34e44 157 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 90 1.1E-9 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HVS_RS06115 4d29dce05f03a303acfe42f75153136c 734 Pfam PF00395 S-layer homology domain 517 559 5.8E-17 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06115 4d29dce05f03a303acfe42f75153136c 734 Pfam PF00395 S-layer homology domain 643 683 5.8E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS06115 4d29dce05f03a303acfe42f75153136c 734 Pfam PF00395 S-layer homology domain 577 620 6.5E-10 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS16110 28092cb32940cf4939c06f227ac66d63 328 SUPERFAMILY SSF55383 52 135 5.36E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16110 28092cb32940cf4939c06f227ac66d63 328 Gene3D G3DSA:3.30.457.10 123 271 3.1E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16110 28092cb32940cf4939c06f227ac66d63 328 Gene3D G3DSA:3.30.457.10 62 122 1.2E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16110 28092cb32940cf4939c06f227ac66d63 328 Gene3D G3DSA:3.30.457.10 9 61 5.2E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS16110 28092cb32940cf4939c06f227ac66d63 328 Pfam PF07833 Copper amine oxidase N-terminal domain 49 141 9.7E-33 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal HVS_RS13270 0bf8bd16161ad849c4fc30b288d7e193 332 Pfam PF13274 Protein of unknown function (DUF4065) 187 280 7.1E-20 T 29-03-2018 IPR025272 Domain of unknown function DUF4065 HVS_RS13270 0bf8bd16161ad849c4fc30b288d7e193 332 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 8 133 8.2E-20 T 29-03-2018 IPR022452 Antitoxin MqsA HVS_RS08455 3f0f0f9c11697fc0517770565557973e 214 Pfam PF00395 S-layer homology domain 51 76 6.4E-4 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS10835 3a88224621addd00a73f22b6b6f571e5 282 Pfam PF14412 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH 106 218 9.3E-6 T 29-03-2018 IPR032871 AHH domain-containing protein HVS_RS02945 f3fad07e1a854f93ead02d6c65b105ea 254 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 5 216 1.3E-29 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 HVS_RS10935 a87c30864564ed270ab10ef84c66c2e1 392 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 25 391 1.2E-162 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HVS_RS10935 a87c30864564ed270ab10ef84c66c2e1 392 PIRSF PIRSF015658 2 392 9.9E-170 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HVS_RS10935 a87c30864564ed270ab10ef84c66c2e1 392 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 26 386 6.8E-153 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 HVS_RS06185 7e88ec66cabea987dcbeee706bfbc72f 237 Gene3D G3DSA:3.40.50.300 80 236 4.9E-9 T 29-03-2018 HVS_RS06185 7e88ec66cabea987dcbeee706bfbc72f 237 SUPERFAMILY SSF53795 81 154 1.76E-7 T 29-03-2018 HVS_RS00955 07a199fa3c408b8de340bdfdc3ebf6c5 75 Pfam PF15603 Immunity protein 74 5 75 2.4E-15 T 29-03-2018 IPR028148 Immunity protein 74 HVS_RS07265 03fe6b30c6d9c29dbbf972bafe04a27f 231 Pfam PF06271 RDD family 5 136 1.7E-16 T 29-03-2018 IPR010432 RDD HVS_RS09560 b893dd3a9e93d38b2ef78d632e66b07b 580 PIRSF PIRSF005690 73 570 2.7E-167 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS09560 b893dd3a9e93d38b2ef78d632e66b07b 580 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 87 555 1.2E-176 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 HVS_RS03575 f4da89a67df4b33bb07dfe0fbcd55a49 201 Pfam PF12801 4Fe-4S binding domain 149 183 0.015 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS03575 f4da89a67df4b33bb07dfe0fbcd55a49 201 Pfam PF12801 4Fe-4S binding domain 25 64 8.5E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain HVS_RS03790 6c0247322a6579f1ada12674977e2a12 109 Pfam PF15569 Immunity protein 40 18 105 3.6E-28 T 29-03-2018 IPR029080 Immunity protein 40 HVS_RS09115 6d34039f9fee91d76aa2213d2e603ed1 458 PIRSF PIRSF006603 2 453 6.5E-92 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS09115 6d34039f9fee91d76aa2213d2e603ed1 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 418 2.3E-65 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS09115 6d34039f9fee91d76aa2213d2e603ed1 458 Pfam PF01554 MatE 244 404 1.4E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS09115 6d34039f9fee91d76aa2213d2e603ed1 458 Pfam PF01554 MatE 19 177 3.3E-35 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 HVS_RS10570 ddac5d0107f1b55bf95d292a210c50f5 577 Pfam PF00395 S-layer homology domain 400 442 5.5E-17 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS10570 ddac5d0107f1b55bf95d292a210c50f5 577 Pfam PF00395 S-layer homology domain 460 503 1.2E-16 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS10570 ddac5d0107f1b55bf95d292a210c50f5 577 Pfam PF00395 S-layer homology domain 523 565 7.6E-12 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS05535 8c4db3edc93e22c0509ac5b8c17aad96 66 Pfam PF16982 Putative Flagellin, Flp1-like, domain 7 52 3.6E-17 T 29-03-2018 IPR031564 Putative Flagellin, Flp1-like domain HVS_RS08470 b1c027915d515161472e546abdfbf217 729 Gene3D G3DSA:3.20.20.80 69 602 1.5E-50 T 29-03-2018 HVS_RS08470 b1c027915d515161472e546abdfbf217 729 Pfam PF02446 4-alpha-glucanotransferase 81 554 9.2E-43 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HVS_RS08470 b1c027915d515161472e546abdfbf217 729 SUPERFAMILY SSF51445 74 549 8.25E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily HVS_RS12310 1cf4dcaee7d63bd75c2cd03ee55d7ae8 181 Pfam PF11667 Putative zincin peptidase 63 161 1.0E-17 T 29-03-2018 IPR021683 Putative zincin peptidase HVS_RS00340 982de542ce9f978b29ef1199ad05ca0a 190 Pfam PF01864 CDP-archaeol synthase 28 188 1.3E-18 T 29-03-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 HVS_RS01130 8ceccf3138af7f256db3118e897e0a6d 52 Pfam PF06044 Dam-replacing family 2 42 4.4E-10 T 29-03-2018 IPR010324 Dam-replacing HVS_RS04080 d394e701583c3531a7f8252b1e7ae887 170 Pfam PF14024 Protein of unknown function (DUF4240) 1 126 1.2E-45 T 29-03-2018 IPR025334 Domain of unknown function (DUF4240 HVS_RS08170 b7db85b9f5129b694f0875682cf6690e 127 Pfam PF10990 Protein of unknown function (DUF2809) 26 109 5.0E-26 T 29-03-2018 IPR021257 Protein of unknown function DUF2809 HVS_RS08205 4d4aa2b7ca9516005bb65cf231cc73b7 69 Gene3D G3DSA:2.60.40.1380 6 68 7.0E-8 T 29-03-2018 HVS_RS08205 4d4aa2b7ca9516005bb65cf231cc73b7 69 SUPERFAMILY SSF49373 8 57 1.1E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments HVS_RS01490 4f121e975e0cff7a63e347634cf9a086 432 Pfam PF14319 Transposase zinc-binding domain 15 121 8.7E-24 T 29-03-2018 IPR026889 Transposase zinc-binding domain HVS_RS01490 4f121e975e0cff7a63e347634cf9a086 432 Pfam PF04986 Putative transposase 153 321 2.5E-39 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 HVS_RS07655 defe4bec2ebf1901ed758dd24f593116 106 Pfam PF12788 YmaF family 46 99 4.4E-8 T 29-03-2018 IPR024307 YmaF HVS_RS05320 2701e3519a1b4ad29112a32085f75e22 219 Gene3D G3DSA:1.20.5.340 40 149 2.6E-4 T 29-03-2018 HVS_RS08225 97780cd045c7d7bae6d5d5ac0cdc7b74 221 Pfam PF11167 Protein of unknown function (DUF2953) 129 177 2.0E-14 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 HVS_RS08210 5c5a897f05fa125f2cc92b9268e9e503 63 Pfam PF07561 Domain of Unknown Function (DUF1540) 12 56 9.9E-12 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 HVS_RS02805 0e6d14da1909471631fe555bc878fc18 1184 SUPERFAMILY SSF52540 199 338 2.0E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02805 0e6d14da1909471631fe555bc878fc18 1184 SUPERFAMILY SSF52540 55 87 2.0E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase HVS_RS02805 0e6d14da1909471631fe555bc878fc18 1184 Gene3D G3DSA:3.40.50.300 43 330 1.5E-7 T 29-03-2018 HVS_RS00910 c55a322a14590942eba6dca2fe643f11 294 Pfam PF14021 Tuberculosis necrotizing toxin 169 219 1.2E-7 T 29-03-2018 IPR025331 Tuberculosis necrotizing toxin HVS_RS06890 60221bf6017fcd7c90d1f6083429fd1f 127 Pfam PF01925 Sulfite exporter TauE/SafE 11 125 6.7E-25 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HVS_RS09140 5fdaafbd41af1c67ca3c44b372c126e0 578 Gene3D G3DSA:1.20.5.1230 161 375 1.9E-4 T 29-03-2018 HVS_RS10105 dfa058b96f4fa36eaf6e07707f751c21 445 Pfam PF03961 Flagellar Assembly Protein A 1 436 2.0E-131 T 29-03-2018 IPR005646 Flagellar assembly protein A HVS_RS10105 dfa058b96f4fa36eaf6e07707f751c21 445 Gene3D G3DSA:2.160.20.70 169 283 1.3E-6 T 29-03-2018 HVS_RS03095 87472dbc367410ef19e576311d832559 247 Pfam PF08874 Domain of unknown function (DUF1835) 69 168 3.2E-12 T 29-03-2018 IPR014973 Protein of unknown function DUF1835 HVS_RS04100 72c58e2903a250aa57214e05ad7e8f51 240 Pfam PF04893 Yip1 domain 27 229 6.2E-16 T 29-03-2018 IPR006977 Yip1 domain GO:0016020 HVS_RS10210 ed021312afe8722b0870b8343b50d856 66 Pfam PF06289 Flagellar protein (FlbD) 1 58 2.4E-28 T 29-03-2018 IPR009384 Flagellar HVS_RS01885 1acfaf22fe97d93da1a619434fb72bd5 67 Gene3D G3DSA:1.20.1070.10 1 67 9.2E-4 T 29-03-2018 HVS_RS01990 6f2ca82ecd4cbf92497a672c77aaf26c 288 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 75 154 1.6E-20 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 HVS_RS03930 7ffaa46bb3cbe4b43e1016be384ac1c6 418 Pfam PF02371 Transposase IS116/IS110/IS902 family 284 373 1.8E-22 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 HVS_RS03930 7ffaa46bb3cbe4b43e1016be384ac1c6 418 Pfam PF01548 Transposase 21 177 4.9E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 HVS_RS15685 4141861e88afabed51f35c399909cb6b 112 Pfam PF14034 Sporulation protein YtrH 7 105 4.8E-37 T 29-03-2018 IPR025689 Sporulation protein YtrH HVS_RS15430 14e16b4a356981520e377376d7ee6f19 284 SMART SM00507 196 252 4.2E-6 T 29-03-2018 IPR003615 HNH nuclease HVS_RS15430 14e16b4a356981520e377376d7ee6f19 284 Gene3D G3DSA:3.40.1800.10 186 267 1.2E-8 T 29-03-2018 HVS_RS14605 b77068a84ac59d944ce364def156fac8 195 Pfam PF07670 Nucleoside recognition 43 150 2.1E-13 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 HVS_RS09630 1477b5dc50f1bea411534bde6688cab7 89 Pfam PF02325 YGGT family 12 85 1.6E-17 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 HVS_RS00430 75c9fddd34e6f57540754d5a01b226f1 116 Gene3D G3DSA:3.40.190.10 1 112 3.0E-4 T 29-03-2018 HVS_RS06205 d9857b95bf5b7fd96448136783043c7e 415 Pfam PF14907 Uncharacterised nucleotidyltransferase 43 285 1.1E-56 T 29-03-2018 HVS_RS06905 c7ef2c586500da857feab50819f4c2ee 215 Pfam PF01810 LysE type translocator 16 206 2.1E-37 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 HVS_RS13890 be409c616ad7e474c9e9a4e5cd57bd5a 400 Pfam PF05552 Conserved TM helix 190 237 1.0E-9 T 29-03-2018 IPR008910 Conserved TM helix HVS_RS13890 be409c616ad7e474c9e9a4e5cd57bd5a 400 Pfam PF05552 Conserved TM helix 99 144 3.2E-14 T 29-03-2018 IPR008910 Conserved TM helix HVS_RS05295 5696a612121170baad19d863d9ff3885 188 Pfam PF02417 Chromate transporter 5 184 8.8E-45 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 HVS_RS15690 acd2e6b9b46ff2b73fff083d619999c9 157 Gene3D G3DSA:3.30.70.1340 32 69 0.0015 T 29-03-2018 HVS_RS04490 fb6619f0c28d411641257474c18295eb 80 Gene3D G3DSA:2.80.10.50 1 78 2.9E-5 T 29-03-2018 HVS_RS09110 c6fd9de9794d8e86c184ff88046e9ebc 182 SUPERFAMILY SSF161266 25 154 3.01E-16 T 29-03-2018 HVS_RS09110 c6fd9de9794d8e86c184ff88046e9ebc 182 Pfam PF07352 Bacteriophage Mu Gam like protein 29 180 1.6E-33 T 29-03-2018 IPR009951 Host-nuclease inhibitor protein Gam GO:0003690|GO:0042262 HVS_RS06615 f73c27b2608c01170dd21de5d9584725 180 Gene3D G3DSA:3.40.50.1010 1 117 2.6E-4 T 29-03-2018 IPR029060 PIN domain-like HVS_RS13005 d77bf0746cd357ef7af9ac7ae669ca41 236 Pfam PF02674 Colicin V production protein 5 54 2.0E-9 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 HVS_RS13005 d77bf0746cd357ef7af9ac7ae669ca41 236 Pfam PF02674 Colicin V production protein 122 222 5.0E-12 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 HVS_RS13025 5e5c841237e106721acc830fb796cca6 458 Pfam PF14238 Domain of unknown function (DUF4340) 68 205 8.9E-24 T 29-03-2018 IPR025641 Domain of unknown function DUF4340 HVS_RS13025 5e5c841237e106721acc830fb796cca6 458 Pfam PF14238 Domain of unknown function (DUF4340) 205 365 7.8E-12 T 29-03-2018 IPR025641 Domain of unknown function DUF4340 HVS_RS00130 eabc92be13b6eef705ffadaece343cf9 40 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 3 39 2.2E-16 T 29-03-2018 IPR009229 Staphylococcal AgrD HVS_RS15580 326bd959a8811d3cb2b9f4e166a93589 399 Pfam PF13349 Putative adhesin 138 376 1.8E-11 T 29-03-2018 IPR025164 Putative adhesin HVS_RS15580 326bd959a8811d3cb2b9f4e166a93589 399 Gene3D G3DSA:1.10.418.10 251 375 0.0016 T 29-03-2018 IPR001715 Calponin homology domain GO:0005515 HVS_RS12240 be5d4410ec545b26541b99ae28061e32 959 Gene3D G3DSA:1.20.1110.10 727 884 0.0074 T 29-03-2018 HVS_RS12240 be5d4410ec545b26541b99ae28061e32 959 Pfam PF02687 FtsX-like permease family 324 422 3.9E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 HVS_RS14630 9b259ae2de4d2ba4050e6b75cecce4bd 291 Pfam PF04468 PSP1 C-terminal conserved region 61 146 3.0E-34 T 29-03-2018 IPR007557 PSP1, C-terminal HVS_RS09195 1fd1f01f8fca8899b527ebbea4b926dc 374 Pfam PF01594 AI-2E family transporter 40 361 1.1E-60 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like HVS_RS03450 359bbffea3988d67085ebe5fbc2dd39a 61 Gene3D G3DSA:3.90.20.10 5 60 1.8E-4 T 29-03-2018 HVS_RS15680 a64bc84a74d3efcd7db6218f53c88a47 318 Pfam PF02690 Na+/Pi-cotransporter 165 256 7.1E-17 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 HVS_RS15680 a64bc84a74d3efcd7db6218f53c88a47 318 Pfam PF02690 Na+/Pi-cotransporter 18 152 4.5E-40 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 HVS_RS15680 a64bc84a74d3efcd7db6218f53c88a47 318 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 7 317 4.5E-68 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 HVS_RS06895 8750f9abe659cf9e6db85d0a341ca45d 129 Pfam PF01925 Sulfite exporter TauE/SafE 3 115 4.1E-24 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 HVS_RS15300 966ac56a850c7d64ce453b653995620b 228 Pfam PF06271 RDD family 16 143 4.3E-23 T 29-03-2018 IPR010432 RDD HVS_RS10985 22ff681a16cfcd5cf70936f89a7173db 303 Gene3D G3DSA:3.30.70.330 65 263 1.8E-4 T 29-03-2018 HVS_RS14175 0958150d9d73b497f75401a6e70c1fdc 252 Pfam PF09407 AbiEi antitoxin C-terminal domain 72 194 4.9E-6 T 29-03-2018 IPR018547 AbiEi antitoxin C-terminal domain HVS_RS03620 a16be8675d8c4a9f496e9411d19a6aed 591 Pfam PF05569 BlaR1 peptidase M56 8 160 2.4E-39 T 29-03-2018 IPR008756 Peptidase M56 HVS_RS04365 2d92a64c2d3dee1c2b00bc32bd86f24c 349 Pfam PF14257 Domain of unknown function (DUF4349) 107 325 8.5E-49 T 29-03-2018 IPR025645 Domain of unknown function DUF4349 HVS_RS10475 f4637dd8c4c8e3a1bbed5d206493100c 60 Pfam PF09388 Spo0E like sporulation regulatory protein 5 41 1.6E-4 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 HVS_RS02515 198545137fe09f20058c6a304aff99ac 170 Pfam PF00395 S-layer homology domain 6 48 1.8E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS02515 198545137fe09f20058c6a304aff99ac 170 Pfam PF00395 S-layer homology domain 71 111 2.7E-13 T 29-03-2018 IPR001119 S-layer homology domain HVS_RS15375 a3fc443cff542a3160ffe01c31e98003 179 Pfam PF06695 Putative small multi-drug export protein 20 141 3.9E-36 T 29-03-2018 IPR009577 Putative small multi-drug export HVS_RS02105 1f038e4c432eb0a35463224978096b6b 102 Pfam PF17253 Family of unknown function (DUF5320) 1 99 1.3E-31 T 29-03-2018 IPR035205 Protein of unknown function DUF5320 HVS_RS09880 5d58f9812fc641b4d4d075d1005887cf 190 Pfam PF12679 ABC-2 family transporter protein 18 188 1.1E-10 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 HVS_RS08180 27b86d96b6ad9a3949c1ed21cb28ef18 264 Pfam PF06114 IrrE N-terminal-like domain 46 176 4.3E-15 T 29-03-2018 IPR010359 IrrE N-terminal-like domain HVS_RS05565 b87f16fc001b0fd42a560b8fbf75fa53 175 Pfam PF01478 Type IV leader peptidase family 7 109 6.8E-14 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 HVS_RS12725 6fa4d63a392650bbf66a1320dadb2a33 329 Gene3D G3DSA:3.80.30.20 81 321 6.3E-5 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe HVS_RS13600 de7843528158c61f3891cc626f90c05b 262 Pfam PF06782 Uncharacterised protein family (UPF0236) 21 260 1.9E-58 T 29-03-2018 IPR009620 Uncharacterised protein family UPF0236 HVS_RS03610 c30e0d94a92080a052cf1feb53f2569d 272 Gene3D G3DSA:3.90.70.10 96 271 2.1E-8 T 29-03-2018 HVS_RS05840 04b360803c5dafce4db4085b5c989f34 141 Pfam PF11187 Protein of unknown function (DUF2974) 37 115 3.8E-5 T 29-03-2018 IPR024499 Protein of unknown function DUF2974 HVS_RS06675 dd28f8c6fa228da24740dc291059d66d 114 SUPERFAMILY SSF50465 6 99 4.22E-9 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HVS_RS02340 64edafe06573f8d74c6b8b69f2f31e64 362 Pfam PF01594 AI-2E family transporter 17 343 6.1E-70 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like HVS_RS01715 532d533960463743ada83971d2142eff 147 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 36 79 9.3E-10 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger