locus-tag	class	description
JFJ84_RS00010	COG0716	FMN binding
JFJ84_RS00020	COG0187	DNA topoisomerase II activity
JFJ84_RS00045	COG0019	diaminopimelate decarboxylase activity
JFJ84_RS00050	COG0733	neurotransmitter:sodium symporter activity
JFJ84_RS00060	COG3070	regulator of competence-specific genes
JFJ84_RS00090	COG0583	DNA-binding transcription factor activity
JFJ84_RS00095	COG0583	DNA-binding transcription factor activity
JFJ84_RS00100	COG2610	gluconate transmembrane transporter activity
JFJ84_RS00105	COG2610	gluconate transmembrane transporter activity
JFJ84_RS00135	COG2195	Cleaves the N-terminal amino acid of tripeptides
JFJ84_RS00155	COG0551	DNA topoisomerase type I activity
JFJ84_RS00170	COG1349	DNA-binding transcription factor activity
JFJ84_RS00175	COG2084	Dehydrogenase
JFJ84_RS00180	COG3395	kinase activity
JFJ84_RS00185	COG0235	Class ii aldolase
JFJ84_RS00195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFJ84_RS00200	COG2610	gluconate transmembrane transporter activity
JFJ84_RS00220	COG2186	Transcriptional regulator
JFJ84_RS00225	COG1063	alcohol dehydrogenase
JFJ84_RS00230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFJ84_RS00235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFJ84_RS00240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFJ84_RS00245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JFJ84_RS00250	COG1984	allophanate hydrolase subunit 2
JFJ84_RS00260	COG1914	H( )-stimulated, divalent metal cation uptake system
JFJ84_RS00275	COG1129	ABC transporter
JFJ84_RS00280	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS00285	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS00295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JFJ84_RS00295	COG0678	peroxiredoxin activity
JFJ84_RS00300	COG0583	DNA-binding transcription factor activity
JFJ84_RS00310	COG0569	domain protein
JFJ84_RS00330	COG2197	response regulator
JFJ84_RS00350	COG2959	enzyme of heme biosynthesis
JFJ84_RS00355	COG3071	HemY protein
JFJ84_RS00370	COG2390	Transcriptional regulator
JFJ84_RS00375	COG1129	ABC transporter
JFJ84_RS00410	COG0051	transcription antitermination factor activity, RNA binding
JFJ84_RS00425	COG0089	rRNA binding
JFJ84_RS00435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JFJ84_RS00445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JFJ84_RS00520	COG0201	protein transport
JFJ84_RS00530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JFJ84_RS00545	COG0202	RNA polymerase activity
JFJ84_RS00555	COG2129	metallophosphoesterase
JFJ84_RS00560	COG3172	ATPase kinase involved in NAD metabolism
JFJ84_RS00575	COG1381	Involved in DNA repair and RecF pathway recombination
JFJ84_RS00580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFJ84_RS00585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFJ84_RS00590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JFJ84_RS00605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFJ84_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
JFJ84_RS00620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFJ84_RS00635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFJ84_RS00640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFJ84_RS00690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JFJ84_RS00700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JFJ84_RS00705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JFJ84_RS00710	COG1555	photosystem II stabilization
JFJ84_RS00715	COG0251	oxidation-reduction process
JFJ84_RS00720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JFJ84_RS00725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JFJ84_RS00730	COG0512	Glutamine amidotransferase of anthranilate synthase
JFJ84_RS00735	COG0783	Belongs to the Dps family
JFJ84_RS00765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFJ84_RS00770	COG0592	DNA-directed DNA polymerase activity
JFJ84_RS00800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JFJ84_RS00830	COG3978	acetolactate synthase activity
JFJ84_RS00835	COG2258	MOSC domain
JFJ84_RS00840	COG3161	chorismate lyase activity
JFJ84_RS00845	COG0557	exoribonuclease II activity
JFJ84_RS00860	COG1045	serine acetyltransferase
JFJ84_RS00875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFJ84_RS00880	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFJ84_RS00900	COG0705	Rhomboid family
JFJ84_RS00905	COG1399	metal-binding, possibly nucleic acid-binding protein
JFJ84_RS00915	COG0416	fatty acid biosynthetic process
JFJ84_RS00925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JFJ84_RS00930	COG1028	Short-chain dehydrogenase reductase Sdr
JFJ84_RS00960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JFJ84_RS00970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JFJ84_RS00990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFJ84_RS01035	COG0196	riboflavin kinase activity
JFJ84_RS01040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JFJ84_RS01045	COG3610	response to peptide
JFJ84_RS01050	COG2966	Psort location CytoplasmicMembrane, score
JFJ84_RS01055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JFJ84_RS01065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JFJ84_RS01100	COG0786	glutamate:sodium symporter activity
JFJ84_RS01130	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JFJ84_RS01140	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JFJ84_RS01145	COG0191	fructose-bisphosphate aldolase activity
JFJ84_RS01155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JFJ84_RS01180	COG1126	abc transporter atp-binding protein
JFJ84_RS01185	COG0765	amino acid transport
JFJ84_RS01190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JFJ84_RS01195	COG0471	metal ion transport
JFJ84_RS01205	COG1575	Belongs to the MenA family. Type 1 subfamily
JFJ84_RS01210	COG1720	tRNA m6t6A37 methyltransferase activity
JFJ84_RS01220	COG1129	ABC transporter
JFJ84_RS01225	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS01230	COG1879	ABC-type sugar transport system periplasmic component
JFJ84_RS01235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFJ84_RS01245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JFJ84_RS01260	COG3083	sulfuric ester hydrolase activity
JFJ84_RS01270	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JFJ84_RS01275	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JFJ84_RS01280	COG1368	sulfuric ester hydrolase activity
JFJ84_RS01285	COG4211	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS01290	COG1129	ABC transporter
JFJ84_RS01295	COG1879	ABC-type sugar transport system periplasmic component
JFJ84_RS01305	COG1085	galactose-1-phosphate uridylyltransferase
JFJ84_RS01310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JFJ84_RS01315	COG2017	converts alpha-aldose to the beta-anomer
JFJ84_RS01330	COG0084	hydrolase, TatD family'
JFJ84_RS01335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JFJ84_RS01345	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JFJ84_RS01350	COG0142	geranyltranstransferase activity
JFJ84_RS01365	COG0697	spore germination
JFJ84_RS01375	COG3023	N-Acetylmuramoyl-L-alanine amidase
JFJ84_RS01380	COG4969	Belongs to the N-Me-Phe pilin family
JFJ84_RS01385	COG1126	abc transporter atp-binding protein
JFJ84_RS01390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JFJ84_RS01395	COG4215	(ABC) transporter
JFJ84_RS01400	COG4160	amino acid transport
JFJ84_RS01410	COG1271	oxidase subunit
JFJ84_RS01415	COG1294	oxidase, subunit
JFJ84_RS01425	COG0824	Thioesterase
JFJ84_RS01430	COG0811	peptide transport
JFJ84_RS01435	COG0848	biopolymer transport protein
JFJ84_RS01440	COG3064	Membrane
JFJ84_RS01470	COG2165	general secretion pathway protein
JFJ84_RS01475	COG4795	General secretion pathway protein
JFJ84_RS01490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JFJ84_RS01505	COG2081	HI0933 family
JFJ84_RS01515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFJ84_RS01520	COG1530	ribonuclease E activity
JFJ84_RS01535	COG4797	methyltransferase
JFJ84_RS01535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JFJ84_RS01545	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JFJ84_RS01550	COG1959	2 iron, 2 sulfur cluster binding
JFJ84_RS01560	COG0822	iron-sulfur transferase activity
JFJ84_RS01570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JFJ84_RS01580	COG0633	Ferredoxin
JFJ84_RS01585	COG2918	glutathione biosynthetic process
JFJ84_RS01585	COG1181	Belongs to the D-alanine--D-alanine ligase family
JFJ84_RS01595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFJ84_RS01600	COG2364	Membrane
JFJ84_RS01635	COG1609	Transcriptional regulator
JFJ84_RS01640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFJ84_RS01645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFJ84_RS01650	COG2176	DNA-directed DNA polymerase activity
JFJ84_RS01660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFJ84_RS01680	COG3085	chromosome segregation
JFJ84_RS01685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFJ84_RS01690	COG3084	Protein conserved in bacteria
JFJ84_RS01700	COG1297	OPT oligopeptide transporter protein
JFJ84_RS01730	COG1686	Belongs to the peptidase S11 family
JFJ84_RS01740	COG0772	Belongs to the SEDS family
JFJ84_RS01745	COG0768	penicillin binding
JFJ84_RS01755	COG0799	negative regulation of ribosome biogenesis
JFJ84_RS01760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFJ84_RS01765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFJ84_RS01770	COG1121	(ABC) transporter
JFJ84_RS01780	COG2920	part of a sulfur-relay system
JFJ84_RS01795	COG0606	chelatase, subunit chli
JFJ84_RS01800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JFJ84_RS01830	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFJ84_RS01835	COG0729	surface antigen
JFJ84_RS01840	COG2911	Protein conserved in bacteria
JFJ84_RS01845	COG0248	Ppx GppA phosphatase
JFJ84_RS01870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JFJ84_RS01875	COG4536	flavin adenine dinucleotide binding
JFJ84_RS01880	COG4137	Cytochrome C assembly protein
JFJ84_RS01885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JFJ84_RS01890	COG0659	secondary active sulfate transmembrane transporter activity
JFJ84_RS01900	COG0582	viral genome integration into host DNA
JFJ84_RS01910	COG0202	RNA polymerase activity
JFJ84_RS01920	COG0270	DNA (cytosine-5-)-methyltransferase activity
JFJ84_RS02035	COG3645	SOS response
JFJ84_RS02235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFJ84_RS02245	COG2990	Protein conserved in bacteria
JFJ84_RS02270	COG0521	Mo-molybdopterin cofactor biosynthetic process
JFJ84_RS02280	COG0628	permease
JFJ84_RS02285	COG2890	protein-(glutamine-N5) methyltransferase activity
JFJ84_RS02295	COG1289	transmembrane transporter activity
JFJ84_RS02310	COG2831	hemolysin activation secretion protein
JFJ84_RS02315	COG3210	domain, Protein
JFJ84_RS02315	COG3210	domain, Protein
JFJ84_RS02370	COG4453	Protein conserved in bacteria
JFJ84_RS02410	COG0675	Transposase, IS605 OrfB family
JFJ84_RS02500	COG3621	Patatin-like phospholipase
JFJ84_RS02505	COG3152	Membrane
JFJ84_RS02520	COG1476	TRANSCRIPTIONal
JFJ84_RS02575	COG0582	viral genome integration into host DNA
JFJ84_RS02585	COG1484	DNA-dependent DNA replication
JFJ84_RS02680	COG0626	cystathionine gamma-synthase activity
JFJ84_RS02690	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFJ84_RS02705	COG0121	glutamine amidotransferase
JFJ84_RS02710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JFJ84_RS02725	COG3250	beta-galactosidase activity
JFJ84_RS02740	COG0312	modulator of DNA gyrase
JFJ84_RS02755	COG1793	dna ligase
JFJ84_RS02760	COG0826	peptidase U32
JFJ84_RS02775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFJ84_RS02780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFJ84_RS02785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFJ84_RS02795	COG0343	queuine tRNA-ribosyltransferase activity
JFJ84_RS02800	COG1862	Preprotein translocase
JFJ84_RS02805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFJ84_RS02810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFJ84_RS02820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JFJ84_RS02865	COG0488	(ABC) transporter
JFJ84_RS02870	COG0545	Peptidyl-prolyl cis-trans isomerase
JFJ84_RS02885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JFJ84_RS02890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JFJ84_RS02900	COG0513	Belongs to the DEAD box helicase family
JFJ84_RS02905	COG0354	folic acid binding
JFJ84_RS02910	COG1561	YicC-like family, N-terminal region
JFJ84_RS02935	COG1509	lysine 2,3-aminomutase activity
JFJ84_RS02940	COG3266	domain, Protein
JFJ84_RS02940	COG3061	Opacity-associated protein A
JFJ84_RS02950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JFJ84_RS02955	COG2814	Major facilitator Superfamily
JFJ84_RS02960	COG4974	Belongs to the 'phage' integrase family
JFJ84_RS02975	COG5295	Hep Hag repeat protein
JFJ84_RS02995	COG0725	ABC transporter, periplasmic molybdate-binding protein
JFJ84_RS03000	COG4149	molybdate abc transporter
JFJ84_RS03005	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JFJ84_RS03045	COG1570	exodeoxyribonuclease VII activity
JFJ84_RS03055	COG0460	homoserine dehydrogenase
JFJ84_RS03055	COG0527	aspartate kinase activity
JFJ84_RS03065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JFJ84_RS03070	COG0735	belongs to the Fur family
JFJ84_RS03075	COG0716	FMN binding
JFJ84_RS03080	COG0596	Alpha beta hydrolase
JFJ84_RS03085	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JFJ84_RS03090	COG0318	PFAM AMP-dependent synthetase and ligase
JFJ84_RS03095	COG3264	Mechanosensitive ion channel
JFJ84_RS03095	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JFJ84_RS03105	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
JFJ84_RS03110	COG0730	response to heat
JFJ84_RS03115	COG1560	Kdo2-lipid A biosynthetic process
JFJ84_RS03125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JFJ84_RS03135	COG3063	Type IV pilus biogenesis stability protein PilW
JFJ84_RS03140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFJ84_RS03170	COG0617	tRNA 3'-terminal CCA addition
JFJ84_RS03175	COG4991	sh3 domain protein
JFJ84_RS03180	COG0306	phosphate transporter
JFJ84_RS03185	COG1392	Phosphate transport regulator
JFJ84_RS03190	COG3025	triphosphatase activity
JFJ84_RS03195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JFJ84_RS03200	COG1522	sequence-specific DNA binding
JFJ84_RS03300	COG0330	HflC and HflK could
JFJ84_RS03305	COG0330	HflC and HflK could
JFJ84_RS03310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JFJ84_RS03315	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
JFJ84_RS03320	COG0456	acetyltransferase
JFJ84_RS03335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JFJ84_RS03340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JFJ84_RS03345	COG0583	DNA-binding transcription factor activity
JFJ84_RS03355	COG0210	DNA helicase
JFJ84_RS03365	COG0204	Acyl-transferase
JFJ84_RS03375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JFJ84_RS03380	COG0346	lactoylglutathione lyase activity
JFJ84_RS03385	COG0012	GTP binding
JFJ84_RS03395	COG2867	negative regulation of translational initiation
JFJ84_RS03405	COG0494	nUDIX hydrolase
JFJ84_RS03415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JFJ84_RS03420	COG0584	glycerophosphoryl diester phosphodiesterase
JFJ84_RS03425	COG2271	Major facilitator Superfamily
JFJ84_RS03430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JFJ84_RS03440	COG0247	lactate metabolic process
JFJ84_RS03445	COG1349	DNA-binding transcription factor activity
JFJ84_RS03455	COG0795	lipopolysaccharide-transporting ATPase activity
JFJ84_RS03460	COG0795	lipopolysaccharide-transporting ATPase activity
JFJ84_RS03475	COG0305	Participates in initiation and elongation during chromosome replication
JFJ84_RS03505	COG0629	single-stranded DNA binding
JFJ84_RS03545	COG2132	Multicopper oxidase
JFJ84_RS03560	COG0667	Aldo Keto reductase
JFJ84_RS03575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFJ84_RS03970	COG2732	(Barnase) inhibitor
JFJ84_RS04030	COG3210	domain, Protein
JFJ84_RS04040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JFJ84_RS04055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JFJ84_RS04065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JFJ84_RS04070	COG0805	protein transport
JFJ84_RS04080	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JFJ84_RS04095	COG0504	CTP synthase activity
JFJ84_RS04130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JFJ84_RS04175	COG4145	pantothenate transmembrane transporter activity
JFJ84_RS04180	COG3924	membrane
JFJ84_RS04185	COG0439	Biotin carboxylase
JFJ84_RS04190	COG0511	ligase activity, forming carbon-carbon bonds
JFJ84_RS04200	COG0330	HflC and HflK could
JFJ84_RS04210	COG2249	NAD(P)H dehydrogenase (quinone) activity
JFJ84_RS04215	COG3381	protein complex oligomerization
JFJ84_RS04220	COG3077	Addiction module antitoxin, RelB DinJ family
JFJ84_RS04225	COG3041	Addiction module toxin RelE StbE family
JFJ84_RS04235	COG0489	protein tyrosine kinase activity
JFJ84_RS04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFJ84_RS04255	COG1137	ATPase activity
JFJ84_RS04260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JFJ84_RS04265	COG3117	lipopolysaccharide transmembrane transporter activity
JFJ84_RS04270	COG1127	ABC transporter
JFJ84_RS04275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JFJ84_RS04280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JFJ84_RS04285	COG2854	intermembrane phospholipid transfer
JFJ84_RS04290	COG3113	response to antibiotic
JFJ84_RS04295	COG5007	Belongs to the BolA IbaG family
JFJ84_RS04300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JFJ84_RS04305	COG0814	amino acid
JFJ84_RS04310	COG2824	Alkylphosphonate utilization operon protein PhnA
JFJ84_RS04315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JFJ84_RS04325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JFJ84_RS04330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JFJ84_RS04335	COG1177	transmembrane transport
JFJ84_RS04340	COG1176	ABC-type spermidine putrescine transport system, permease component I
JFJ84_RS04345	COG3842	ATPase activity
JFJ84_RS04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFJ84_RS04360	COG5295	Hep Hag repeat protein
JFJ84_RS04405	COG0860	N-Acetylmuramoyl-L-alanine amidase
JFJ84_RS04405	COG1388	LysM domain
JFJ84_RS04410	COG0802	atpase or kinase
JFJ84_RS04415	COG3683	transport system, periplasmic component
JFJ84_RS04420	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JFJ84_RS04435	COG2949	membrane
JFJ84_RS04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JFJ84_RS04455	COG3108	Peptidase M15
JFJ84_RS04460	COG2989	Protein conserved in bacteria
JFJ84_RS04465	COG0793	Belongs to the peptidase S41A family
JFJ84_RS04475	COG2995	paraquat-inducible protein a
JFJ84_RS04480	COG3008	intermembrane lipid transfer
JFJ84_RS04490	COG0733	neurotransmitter:sodium symporter activity
JFJ84_RS04495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JFJ84_RS04510	COG4658	electron transport chain
JFJ84_RS04515	COG4656	Part of a membrane complex involved in electron transport
JFJ84_RS04540	COG5295	Hep Hag repeat protein
JFJ84_RS04545	COG1090	epimerase
JFJ84_RS04560	COG0583	DNA-binding transcription factor activity
JFJ84_RS04565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JFJ84_RS04570	COG1687	branched-chain amino acid
JFJ84_RS04580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFJ84_RS04580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFJ84_RS04585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFJ84_RS04590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JFJ84_RS04610	COG0277	FAD linked oxidase domain protein
JFJ84_RS04610	COG0247	lactate metabolic process
JFJ84_RS04620	COG0671	phosphoesterase, PA-phosphatase related
JFJ84_RS04625	COG1940	carbohydrate kinase activity
JFJ84_RS04630	COG1115	amino acid carrier protein
JFJ84_RS04635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFJ84_RS04640	COG1121	(ABC) transporter
JFJ84_RS04645	COG0739	heme binding
JFJ84_RS04660	COG0583	DNA-binding transcription factor activity
JFJ84_RS04670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JFJ84_RS04680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JFJ84_RS04685	COG0314	molybdopterin synthase activity
JFJ84_RS04695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JFJ84_RS04700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JFJ84_RS04705	COG0617	tRNA 3'-terminal CCA addition
JFJ84_RS04710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JFJ84_RS04715	COG0658	competence protein
JFJ84_RS04715	COG2333	competence protein COMEC
JFJ84_RS04720	COG1132	(ABC) transporter
JFJ84_RS04765	COG1595	DNA-templated transcription, initiation
JFJ84_RS04780	COG2056	Na+-H+ antiporter family
JFJ84_RS04805	COG4143	(ABC) transporter
JFJ84_RS04810	COG1178	ABC-type Fe3 transport system permease component
JFJ84_RS04815	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JFJ84_RS04825	COG5295	Hep Hag repeat protein
JFJ84_RS04845	COG1393	Belongs to the ArsC family
JFJ84_RS04850	COG1534	Rna-binding protein
JFJ84_RS04865	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JFJ84_RS04895	COG1643	Atp-dependent helicase
JFJ84_RS04900	COG0494	nUDIX hydrolase
JFJ84_RS04920	COG0528	UMP kinase activity
JFJ84_RS04930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JFJ84_RS04935	COG5413	integral membrane protein
JFJ84_RS04945	COG0575	Belongs to the CDS family
JFJ84_RS04950	COG0750	zinc metalloprotease
JFJ84_RS04965	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFJ84_RS04970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JFJ84_RS04975	COG0539	negative regulation of cytoplasmic translation
JFJ84_RS04985	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JFJ84_RS04990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JFJ84_RS05000	COG4453	Protein conserved in bacteria
JFJ84_RS05015	COG3041	Addiction module toxin RelE StbE family
JFJ84_RS05020	COG3077	Addiction module antitoxin, RelB DinJ family
JFJ84_RS05025	COG2166	iron-sulfur cluster assembly
JFJ84_RS05035	COG1525	nuclease
JFJ84_RS05040	COG1380	Effector of murein hydrolase LrgA
JFJ84_RS05045	COG1346	cytolysis
JFJ84_RS05055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JFJ84_RS05060	COG0633	Ferredoxin
JFJ84_RS05065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFJ84_RS05075	COG0567	Dehydrogenase, E1 component
JFJ84_RS05080	COG0508	dehydrogenase complex catalyzes the overall conversion of
JFJ84_RS05090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JFJ84_RS05100	COG3102	Protein conserved in bacteria
JFJ84_RS05110	COG3133	Outer membrane lipoprotein
JFJ84_RS05125	COG1714	RDD family
JFJ84_RS05145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFJ84_RS05150	COG4591	ABC-type transport system involved in lipoprotein release permease component
JFJ84_RS05155	COG1136	(ABC) transporter
JFJ84_RS05160	COG4591	ABC-type transport system involved in lipoprotein release permease component
JFJ84_RS05165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JFJ84_RS05170	COG0305	Participates in initiation and elongation during chromosome replication
JFJ84_RS05200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JFJ84_RS05210	COG1074	ATP-dependent DNA helicase activity
JFJ84_RS05215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JFJ84_RS05220	COG0076	glutamate decarboxylase activity
JFJ84_RS05225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JFJ84_RS05235	COG1349	DNA-binding transcription factor activity
JFJ84_RS05240	COG1528	Iron-storage protein
JFJ84_RS05245	COG1528	Iron-storage protein
JFJ84_RS05250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JFJ84_RS05255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JFJ84_RS05255	COG0517	IMP dehydrogenase activity
JFJ84_RS05265	COG1286	toxin biosynthetic process
JFJ84_RS05275	COG0163	prenyltransferase activity
JFJ84_RS05280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFJ84_RS05285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JFJ84_RS05290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JFJ84_RS05295	COG0303	'Molybdopterin
JFJ84_RS05305	COG0778	Nitroreductase
JFJ84_RS05310	COG0616	signal peptide processing
JFJ84_RS05315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JFJ84_RS05320	COG2431	L-lysine efflux transmembrane transporter activity
JFJ84_RS05330	COG0142	geranyltranstransferase activity
JFJ84_RS05335	COG1722	exodeoxyribonuclease VII activity
JFJ84_RS05385	COG0612	Peptidase, M16
JFJ84_RS05395	COG1640	4-alpha-glucanotransferase
JFJ84_RS05400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JFJ84_RS05405	COG1523	belongs to the glycosyl hydrolase 13 family
JFJ84_RS05415	COG0297	glycogen (starch) synthase activity
JFJ84_RS05425	COG0308	aminopeptidase N
JFJ84_RS05430	COG0613	PHP domain protein
JFJ84_RS05435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFJ84_RS05445	COG0285	dihydrofolate synthase activity
JFJ84_RS05450	COG0589	response to stress
JFJ84_RS05455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JFJ84_RS05475	COG0586	Pfam SNARE associated Golgi protein
JFJ84_RS05490	COG2925	Exonuclease
JFJ84_RS05500	COG1943	Transposase
JFJ84_RS05520	COG0697	spore germination
JFJ84_RS05525	COG3586	endonuclease activity
JFJ84_RS05570	COG1067	ATP-dependent peptidase activity
JFJ84_RS05580	COG1278	Cold shock
JFJ84_RS05585	COG3140	Belongs to the UPF0181 family
JFJ84_RS05595	COG3098	single-species biofilm formation
JFJ84_RS05600	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JFJ84_RS05610	COG1611	Belongs to the LOG family
JFJ84_RS05615	COG0842	Transport permease protein
JFJ84_RS05620	COG1131	(ABC) transporter
JFJ84_RS05625	COG3101	peptidyl-lysine hydroxylation
JFJ84_RS05630	COG2252	PERMEase
JFJ84_RS05635	COG3118	belongs to the thioredoxin family
JFJ84_RS05655	COG0616	signal peptide processing
JFJ84_RS05660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JFJ84_RS05665	COG0512	Glutamine amidotransferase of anthranilate synthase
JFJ84_RS05675	COG0134	indole-3-glycerol-phosphate synthase activity
JFJ84_RS05675	COG0135	phosphoribosylanthranilate isomerase activity
JFJ84_RS05690	COG0288	reversible hydration of carbon dioxide
JFJ84_RS05695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JFJ84_RS05700	COG1448	Aminotransferase
JFJ84_RS05705	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
JFJ84_RS05710	COG0708	Exodeoxyribonuclease III
JFJ84_RS05720	COG1280	lysine exporter protein (LysE YggA)
JFJ84_RS05725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JFJ84_RS05730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JFJ84_RS05750	COG0024	Methionine aminopeptidase
JFJ84_RS05760	COG3112	Uncharacterised protein family (UPF0231)
JFJ84_RS05765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JFJ84_RS05790	COG0195	Participates in both transcription termination and antitermination
JFJ84_RS05805	COG0515	serine threonine protein kinase
JFJ84_RS05810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JFJ84_RS05815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFJ84_RS05820	COG3105	Protein conserved in bacteria
JFJ84_RS05830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JFJ84_RS05835	COG0307	riboflavin synthase, alpha
JFJ84_RS05860	COG3005	denitrification pathway
JFJ84_RS05865	COG0243	molybdopterin cofactor binding
JFJ84_RS05885	COG0280	phosphate acetyltransferase
JFJ84_RS05885	COG0857	belongs to the CobB CobQ family
JFJ84_RS05900	COG0814	amino acid
JFJ84_RS05905	COG0167	dihydroorotate dehydrogenase activity
JFJ84_RS05915	COG2252	PERMEase
JFJ84_RS05920	COG2814	Major facilitator Superfamily
JFJ84_RS05925	COG0187	DNA topoisomerase II activity
JFJ84_RS05930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JFJ84_RS05935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JFJ84_RS05945	COG3106	COG3106 Predicted ATPase
JFJ84_RS05950	COG4166	transmembrane transport
JFJ84_RS05955	COG4168	peptide transport system, permease
JFJ84_RS05960	COG4171	peptide transport system, permease
JFJ84_RS05965	COG4172	Belongs to the ABC transporter superfamily
JFJ84_RS05970	COG4172	Belongs to the ABC transporter superfamily
JFJ84_RS05985	COG4166	transmembrane transport
JFJ84_RS05995	COG1609	Transcriptional regulator
JFJ84_RS05995	COG2207	Transcriptional regulator
JFJ84_RS06000	COG1757	Na H antiporter
JFJ84_RS06005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JFJ84_RS06010	COG0339	signal peptide processing
JFJ84_RS06050	COG5295	Hep Hag repeat protein
JFJ84_RS06080	COG1757	Na H antiporter
JFJ84_RS06090	COG0788	formyltetrahydrofolate deformylase activity
JFJ84_RS06100	COG0277	FAD linked oxidase domain protein
JFJ84_RS06105	COG1840	ABC-type Fe3 transport system, periplasmic component
JFJ84_RS06115	COG3842	ATPase activity
JFJ84_RS06120	COG0814	amino acid
JFJ84_RS06125	COG3691	Protein conserved in bacteria
JFJ84_RS06130	COG0778	Nitroreductase
JFJ84_RS06135	COG0561	phosphatase activity
JFJ84_RS06145	COG2267	carboxylic ester hydrolase activity
JFJ84_RS06150	COG0561	phosphatase activity
JFJ84_RS06155	COG0235	Class ii aldolase
JFJ84_RS06160	COG3623	hexulose-6-phosphate isomerase
JFJ84_RS06165	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JFJ84_RS06175	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS06185	COG1879	ABC-type sugar transport system periplasmic component
JFJ84_RS06205	COG1129	ABC transporter
JFJ84_RS06210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFJ84_RS06215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFJ84_RS06220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFJ84_RS06230	COG1414	Transcriptional regulator
JFJ84_RS06235	COG1940	carbohydrate kinase activity
JFJ84_RS06245	COG2969	positive regulation of protein catabolic process
JFJ84_RS06270	COG0738	Major facilitator superfamily
JFJ84_RS06275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFJ84_RS06285	COG1349	DNA-binding transcription factor activity
JFJ84_RS06290	COG1538	Outer membrane efflux protein
JFJ84_RS06310	COG0009	L-threonylcarbamoyladenylate synthase
JFJ84_RS06330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JFJ84_RS06335	COG2823	Periplasmic or secreted lipoprotein
JFJ84_RS06340	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JFJ84_RS06345	COG0318	PFAM AMP-dependent synthetase and ligase
JFJ84_RS06350	COG1214	PFAM Peptidase M22, glycoprotease
JFJ84_RS06355	COG1199	ATP-dependent helicase activity
JFJ84_RS06365	COG2062	phosphohistidine phosphatase, SixA
JFJ84_RS06375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JFJ84_RS06395	COG3475	LICD family
JFJ84_RS06400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JFJ84_RS06405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JFJ84_RS06410	COG3721	Heme iron utilization protein
JFJ84_RS06415	COG0748	coenzyme F420 binding
JFJ84_RS06425	COG4771	TonB-dependent receptor
JFJ84_RS06425	COG1629	transport
JFJ84_RS06445	COG0210	DNA helicase
JFJ84_RS06450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFJ84_RS06450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFJ84_RS06460	COG1530	ribonuclease E activity
JFJ84_RS06470	COG0745	RESPONSE REGULATOR receiver
JFJ84_RS06480	COG1556	Lactate utilization protein
JFJ84_RS06485	COG1139	Iron-sulfur cluster binding protein
JFJ84_RS06490	COG0247	lactate metabolic process
JFJ84_RS06495	COG1620	l-lactate permease
JFJ84_RS06500	COG1088	dTDP-glucose 4,6-dehydratase activity
JFJ84_RS06505	COG1083	cytidylyl-transferase
JFJ84_RS06515	COG0513	Belongs to the DEAD box helicase family
JFJ84_RS06530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFJ84_RS06540	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JFJ84_RS06550	COG2731	YhcH YjgK YiaL family protein
JFJ84_RS06555	COG1737	Transcriptional regulator
JFJ84_RS06580	COG0811	peptide transport
JFJ84_RS06585	COG0848	biopolymer transport protein
JFJ84_RS06600	COG0560	Phosphoserine phosphatase
JFJ84_RS06610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JFJ84_RS06630	COG0006	proline dipeptidase activity
JFJ84_RS06635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFJ84_RS06640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFJ84_RS06660	COG3730	PTS system glucitol sorbitol-specific
JFJ84_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
JFJ84_RS06680	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFJ84_RS06685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFJ84_RS06690	COG1349	DNA-binding transcription factor activity
JFJ84_RS06695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JFJ84_RS06700	COG1605	Chorismate mutase
JFJ84_RS06700	COG0287	Prephenate dehydrogenase
JFJ84_RS06705	COG1476	TRANSCRIPTIONal
JFJ84_RS06720	COG3283	Transcriptional regulator of aromatic amino acids metabolism
JFJ84_RS06725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JFJ84_RS06735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFJ84_RS06740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JFJ84_RS06745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JFJ84_RS06750	COG4972	Pilus assembly protein
JFJ84_RS06765	COG4796	Type ii and iii secretion system protein
JFJ84_RS06780	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JFJ84_RS06785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JFJ84_RS06790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFJ84_RS06830	COG3956	TIGRFAM MazG family protein
JFJ84_RS06835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JFJ84_RS06840	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JFJ84_RS06845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JFJ84_RS06850	COG1792	Involved in formation and maintenance of cell shape
JFJ84_RS06855	COG1077	Cell shape determining protein MreB Mrl
JFJ84_RS06870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JFJ84_RS06890	COG0537	adenosine 5'-monophosphoramidase activity
JFJ84_RS06895	COG2116	formate transmembrane transporter activity
JFJ84_RS06900	COG1882	Formate acetyltransferase
JFJ84_RS06905	COG2259	Doxx family
JFJ84_RS06915	COG3220	belongs to the UPF0276 family
JFJ84_RS06920	COG3219	Protein conserved in bacteria
JFJ84_RS06925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JFJ84_RS06930	COG0492	ferredoxin-NADP+ reductase activity
JFJ84_RS06935	COG4988	ABC transporter
JFJ84_RS06940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JFJ84_RS06945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JFJ84_RS06955	COG2833	Protein of unknown function (DUF455)
JFJ84_RS06960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JFJ84_RS06985	COG0469	pyruvate kinase activity
JFJ84_RS06990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JFJ84_RS07015	COG2932	Transcriptional regulator
JFJ84_RS07020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFJ84_RS07025	COG0508	dehydrogenase complex catalyzes the overall conversion of
JFJ84_RS07030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JFJ84_RS07035	COG2190	(PTS) system
JFJ84_RS07040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JFJ84_RS07045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFJ84_RS07065	COG0004	ammonium transporteR
JFJ84_RS07070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFJ84_RS07080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JFJ84_RS07085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JFJ84_RS07095	COG2314	TM2 domain
JFJ84_RS07130	COG0251	oxidation-reduction process
JFJ84_RS07140	COG0497	DNA recombination
JFJ84_RS07160	COG0385	Bile acid
JFJ84_RS07180	COG1840	ABC-type Fe3 transport system, periplasmic component
JFJ84_RS07185	COG1840	ABC-type Fe3 transport system, periplasmic component
JFJ84_RS07195	COG3842	ATPase activity
JFJ84_RS07215	COG1216	Glycosyl transferase, family 2
JFJ84_RS07230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JFJ84_RS07240	COG0436	Aminotransferase
JFJ84_RS07255	COG2267	carboxylic ester hydrolase activity
JFJ84_RS07260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFJ84_RS07265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFJ84_RS07280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JFJ84_RS07285	COG2926	Belongs to the UPF0265 family
JFJ84_RS07290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFJ84_RS07290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFJ84_RS07295	COG3715	PTS system
JFJ84_RS07300	COG3716	PTS system mannose fructose sorbose family IID component
JFJ84_RS07310	COG1482	cell wall glycoprotein biosynthetic process
JFJ84_RS07315	COG0328	RNA-DNA hybrid ribonuclease activity
JFJ84_RS07320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JFJ84_RS07340	COG1070	Carbohydrate kinase
JFJ84_RS07350	COG4213	ABC transporter substrate-binding protein
JFJ84_RS07355	COG1129	ABC transporter
JFJ84_RS07360	COG4214	carbohydrate transport
JFJ84_RS07375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JFJ84_RS07380	COG0494	nUDIX hydrolase
JFJ84_RS07385	COG1876	peptidase activity
JFJ84_RS07395	COG1393	Belongs to the ArsC family
JFJ84_RS07400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JFJ84_RS07400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JFJ84_RS07405	COG1560	Kdo2-lipid A biosynthetic process
JFJ84_RS07410	COG4383	Mu-like prophage protein gp29
JFJ84_RS07455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JFJ84_RS07530	COG4545	Glutaredoxin-related protein
JFJ84_RS07540	COG2095	MarC family integral membrane protein
JFJ84_RS07545	COG5295	Hep Hag repeat protein
JFJ84_RS07565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFJ84_RS07595	COG0681	Belongs to the peptidase S26 family
JFJ84_RS07610	COG3069	C4-dicarboxylate transmembrane transporter activity
JFJ84_RS07635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JFJ84_RS07640	COG3722	fumarate hydratase activity
JFJ84_RS07645	COG0246	Mannitol dehydrogenase
JFJ84_RS07655	COG0784	Response regulator, receiver
JFJ84_RS07655	COG4191	Histidine kinase
JFJ84_RS07665	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS07695	COG1940	carbohydrate kinase activity
JFJ84_RS07700	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JFJ84_RS07705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JFJ84_RS07710	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JFJ84_RS07745	COG3177	Filamentation induced by cAMP protein fic
JFJ84_RS07755	COG2927	DNA polymerase III (CHI subunit)
JFJ84_RS07775	COG1607	acyl-coa hydrolase
JFJ84_RS07780	COG2350	Protein conserved in bacteria
JFJ84_RS07800	COG0444	Belongs to the ABC transporter superfamily
JFJ84_RS07805	COG4608	Belongs to the ABC transporter superfamily
JFJ84_RS07815	COG0675	Transposase, IS605 OrfB family
JFJ84_RS07830	COG1053	succinate dehydrogenase
JFJ84_RS07835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JFJ84_RS07865	COG0450	alkyl hydroperoxide reductase
JFJ84_RS07870	COG0626	cystathionine gamma-synthase activity
JFJ84_RS07885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JFJ84_RS07895	COG3078	GTPase activator activity
JFJ84_RS07915	COG1027	Aspartate ammonia-lyase
JFJ84_RS07920	COG0280	phosphate acetyltransferase
JFJ84_RS07920	COG0281	malic enzyme
JFJ84_RS07930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JFJ84_RS07935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JFJ84_RS07940	COG1115	amino acid carrier protein
JFJ84_RS07945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JFJ84_RS07955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JFJ84_RS07960	COG1459	type II secretion system
JFJ84_RS07990	COG2091	lysine biosynthetic process via aminoadipic acid
JFJ84_RS08035	COG4783	chaperone-mediated protein folding
JFJ84_RS08040	COG4783	chaperone-mediated protein folding
JFJ84_RS08050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFJ84_RS08140	COG1217	gtp-binding protein TYPA
JFJ84_RS08150	COG0728	peptidoglycan biosynthetic process
JFJ84_RS08155	COG0552	protein localization to endoplasmic reticulum
JFJ84_RS08160	COG0742	ribosomal rna small subunit methyltransferase
JFJ84_RS08165	COG0758	DNA mediated transformation
JFJ84_RS08180	COG2860	membrane
JFJ84_RS08200	COG2976	Protein conserved in bacteria
JFJ84_RS08215	COG1426	Protein conserved in bacteria
JFJ84_RS08220	COG0784	Response regulator, receiver
JFJ84_RS08220	COG5002	protein histidine kinase activity
JFJ84_RS08220	COG2198	Histidine kinase
JFJ84_RS08240	COG1138	Cytochrome C-type biogenesis protein
JFJ84_RS08250	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFJ84_RS08255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFJ84_RS08260	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFJ84_RS08265	COG4133	protoheme IX ABC transporter activity
JFJ84_RS08305	COG2937	Belongs to the GPAT DAPAT family
JFJ84_RS08330	COG5295	Hep Hag repeat protein
JFJ84_RS08350	COG2358	TRAP transporter, solute receptor (TAXI family
JFJ84_RS08355	COG3265	gluconokinase activity
JFJ84_RS08360	COG2610	gluconate transmembrane transporter activity
JFJ84_RS08370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JFJ84_RS08375	COG0569	domain protein
JFJ84_RS08380	COG4166	transmembrane transport
JFJ84_RS08385	COG4166	transmembrane transport
JFJ84_RS08390	COG0601	transmembrane transport
JFJ84_RS08395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFJ84_RS08400	COG4172	Belongs to the ABC transporter superfamily
JFJ84_RS08415	COG0488	(ABC) transporter
JFJ84_RS08430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JFJ84_RS08435	COG1496	oxidoreductase activity
JFJ84_RS08450	COG1605	Chorismate mutase
JFJ84_RS08450	COG0077	Prephenate dehydratase
JFJ84_RS08460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JFJ84_RS08465	COG0849	cell division
JFJ84_RS08470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JFJ84_RS08485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JFJ84_RS08505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JFJ84_RS08510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JFJ84_RS08515	COG0768	penicillin binding
JFJ84_RS08520	COG3116	cell division
JFJ84_RS08535	COG1966	Carbon starvation protein
JFJ84_RS08545	COG1444	tRNA N-acetyltransferase activity
JFJ84_RS08555	COG1702	phosphate starvation-inducible protein PhoH
JFJ84_RS08565	COG0387	Pfam Sodium calcium exchanger
JFJ84_RS08595	COG1473	amidohydrolase
JFJ84_RS08605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JFJ84_RS08620	COG1285	pathogenesis
JFJ84_RS08630	COG1522	sequence-specific DNA binding
JFJ84_RS08635	COG2861	carbohydrate metabolic process
JFJ84_RS08640	COG4942	peptidase
JFJ84_RS08655	COG1349	DNA-binding transcription factor activity
JFJ84_RS08660	COG0738	Major facilitator superfamily
JFJ84_RS08665	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
JFJ84_RS08670	COG1070	Carbohydrate kinase
JFJ84_RS08680	COG0235	Class ii aldolase
JFJ84_RS08715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JFJ84_RS08720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFJ84_RS08730	COG0194	GDP metabolic process
JFJ84_RS08735	COG3475	LICD family
JFJ84_RS08740	COG4750	Nucleotidyl transferase
JFJ84_RS08745	COG0697	spore germination
JFJ84_RS08760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JFJ84_RS08765	COG0602	queuosine metabolic process
JFJ84_RS08770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JFJ84_RS08770	COG1328	CTP reductase activity
JFJ84_RS08775	COG4178	(ABC) transporter
JFJ84_RS08790	COG2801	Transposase and inactivated derivatives
JFJ84_RS08795	COG2801	Transposase and inactivated derivatives
JFJ84_RS08845	COG4382	Mu-like prophage protein Gp16
JFJ84_RS08855	COG3561	AntA/AntB antirepressor
JFJ84_RS08870	COG3023	N-Acetylmuramoyl-L-alanine amidase
JFJ84_RS08905	COG4383	Mu-like prophage protein gp29
JFJ84_RS08910	COG2369	cell adhesion
JFJ84_RS08920	COG4397	Mu-like prophage major head subunit gpT
JFJ84_RS08985	COG4381	Mu-like prophage protein gp46
JFJ84_RS09055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JFJ84_RS09060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFJ84_RS09080	COG2814	Major facilitator Superfamily
JFJ84_RS09085	COG1584	GPR1 FUN34 yaaH family protein
JFJ84_RS09100	COG2826	transposase and inactivated derivatives, IS30 family
JFJ84_RS09105	COG2826	transposase and inactivated derivatives, IS30 family
JFJ84_RS09110	COG1253	flavin adenine dinucleotide binding
JFJ84_RS09120	COG0084	hydrolase, TatD family'
JFJ84_RS09125	COG0470	DNA polymerase III
JFJ84_RS09135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JFJ84_RS09145	COG1040	competence protein
JFJ84_RS09155	COG1114	Component of the transport system for branched-chain amino acids
JFJ84_RS09160	COG2183	response to ionizing radiation
JFJ84_RS09175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JFJ84_RS09180	COG0475	glutathione-regulated potassium exporter activity
JFJ84_RS09180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JFJ84_RS09210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JFJ84_RS09210	COG0047	phosphoribosylformylglycinamidine synthase activity
JFJ84_RS09215	COG3005	denitrification pathway
JFJ84_RS09220	COG3043	anaerobic respiration
JFJ84_RS09225	COG0348	domain, Protein
JFJ84_RS09230	COG0437	4 iron, 4 sulfur cluster binding
JFJ84_RS09240	COG3062	negative regulation of establishment of protein localization
JFJ84_RS09245	COG3850	Histidine kinase
JFJ84_RS09260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFJ84_RS09265	COG1741	Belongs to the pirin family
JFJ84_RS09270	COG3691	Protein conserved in bacteria
JFJ84_RS09280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JFJ84_RS09295	COG1120	ATPase activity
JFJ84_RS09300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFJ84_RS09305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFJ84_RS09310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JFJ84_RS09315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFJ84_RS09320	COG2177	Part of the ABC transporter FtsEX involved in
JFJ84_RS09325	COG2884	Cell division ATP-binding protein ftsE
JFJ84_RS09330	COG1466	dna polymerase III delta subunit
JFJ84_RS09335	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JFJ84_RS09355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JFJ84_RS09360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JFJ84_RS09365	COG0814	amino acid
JFJ84_RS09375	COG0501	Belongs to the peptidase M48B family
JFJ84_RS09380	COG0564	pseudouridine synthase activity
JFJ84_RS09395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFJ84_RS09400	COG1446	asparaginase
JFJ84_RS09405	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JFJ84_RS09410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFJ84_RS09415	COG1447	Phosphotransferase system cellobiose-specific component IIA
JFJ84_RS09425	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JFJ84_RS09450	COG3835	regulator
JFJ84_RS09455	COG2610	gluconate transmembrane transporter activity
JFJ84_RS09460	COG1929	Belongs to the glycerate kinase type-1 family
JFJ84_RS09485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JFJ84_RS09500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JFJ84_RS09505	COG1349	DNA-binding transcription factor activity
JFJ84_RS09515	COG3068	Protein conserved in bacteria
JFJ84_RS09535	COG0698	ribose 5-phosphate isomerase
JFJ84_RS09540	COG1940	carbohydrate kinase activity
JFJ84_RS09545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JFJ84_RS09550	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS09555	COG1129	ABC transporter
JFJ84_RS09560	COG1879	ABC-type sugar transport system periplasmic component
JFJ84_RS09565	COG1737	Transcriptional regulator
JFJ84_RS09580	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFJ84_RS09635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JFJ84_RS09640	COG1739	Uncharacterized protein family UPF0029
JFJ84_RS09645	COG0425	Belongs to the sulfur carrier protein TusA family
JFJ84_RS09655	COG1982	Orn Lys Arg decarboxylase major
JFJ84_RS09660	COG0531	amino acid
JFJ84_RS09665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JFJ84_RS09670	COG0673	inositol 2-dehydrogenase activity
JFJ84_RS09685	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFJ84_RS09690	COG1129	ABC transporter
JFJ84_RS09695	COG1879	ABC-type sugar transport system periplasmic component
JFJ84_RS09700	COG1879	ABC-type sugar transport system periplasmic component
JFJ84_RS09705	COG0673	inositol 2-dehydrogenase activity
JFJ84_RS09715	COG0823	Involved in the tonB-independent uptake of proteins
JFJ84_RS09725	COG2826	transposase and inactivated derivatives, IS30 family
JFJ84_RS09735	COG3718	enzyme involved in inositol metabolism
JFJ84_RS09740	COG1132	(ABC) transporter
JFJ84_RS09750	COG1519	Transferase
JFJ84_RS09760	COG0456	acetyltransferase
JFJ84_RS09765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JFJ84_RS09785	COG2186	Transcriptional regulator
JFJ84_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
JFJ84_RS09805	COG2211	Major facilitator Superfamily
JFJ84_RS09815	COG0800	Aldolase
JFJ84_RS09825	COG1595	DNA-templated transcription, initiation
JFJ84_RS09830	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JFJ84_RS09835	COG3026	antisigma factor binding
JFJ84_RS09840	COG3086	response to oxidative stress
JFJ84_RS09845	COG1763	Mo-molybdopterin cofactor biosynthetic process
JFJ84_RS09865	COG0859	PFAM glycosyl transferase family 9
JFJ84_RS09895	COG0590	tRNA wobble adenosine to inosine editing
JFJ84_RS09910	COG0730	response to heat
JFJ84_RS09925	COG3091	SprT-like family
JFJ84_RS09955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JFJ84_RS09960	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
JFJ84_RS10010	COG2923	Belongs to the DsrF TusC family
JFJ84_RS10020	COG2964	Protein conserved in bacteria
JFJ84_RS10025	COG0545	Peptidyl-prolyl cis-trans isomerase
JFJ84_RS10040	COG1187	pseudouridine synthase activity
JFJ84_RS10050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JFJ84_RS10085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JFJ84_RS10095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JFJ84_RS10100	COG0363	glucosamine-6-phosphate deaminase activity
JFJ84_RS10110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JFJ84_RS10115	COG2853	Lipoprotein
JFJ84_RS10130	COG0762	integral membrane protein
JFJ84_RS10140	COG3171	Protein conserved in bacteria
JFJ84_RS10145	COG0583	DNA-binding transcription factor activity
JFJ84_RS10170	COG1194	a g-specific adenine glycosylase
JFJ84_RS10185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFJ84_RS10195	COG3005	denitrification pathway
JFJ84_RS10220	COG2991	Protein conserved in bacteria
JFJ84_RS10225	COG1477	protein flavinylation
JFJ84_RS10235	COG2871	sodium ion transport
JFJ84_RS10245	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFJ84_RS10265	COG0271	Belongs to the BolA IbaG family
JFJ84_RS10270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JFJ84_RS10280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JFJ84_RS10310	COG3312	ion transport