locus-tag	class	description
IMCC20628_RS00035	COG0583	DNA-binding transcription factor activity
IMCC20628_RS00045	COG5016	pyruvate
IMCC20628_RS00045	COG0511	ligase activity, forming carbon-carbon bonds
IMCC20628_RS00050	COG0439	Biotin carboxylase
IMCC20628_RS00060	COG1984	allophanate hydrolase subunit 2
IMCC20628_RS00090	COG3842	ATPase activity
IMCC20628_RS00095	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00110	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00120	COG3842	ATPase activity
IMCC20628_RS00150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS00165	COG2235	arginine
IMCC20628_RS00170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMCC20628_RS00180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC20628_RS00210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC20628_RS00215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMCC20628_RS00220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC20628_RS00225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC20628_RS00240	COG0747	negative chemotaxis
IMCC20628_RS00245	COG0601	transmembrane transport
IMCC20628_RS00250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS00255	COG0444	Belongs to the ABC transporter superfamily
IMCC20628_RS00260	COG4608	Belongs to the ABC transporter superfamily
IMCC20628_RS00270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC20628_RS00300	COG3257	ureidoglycine aminohydrolase activity
IMCC20628_RS00315	COG2010	Cytochrome c
IMCC20628_RS00325	COG3278	Belongs to the heme-copper respiratory oxidase family
IMCC20628_RS00360	COG1959	2 iron, 2 sulfur cluster binding
IMCC20628_RS00375	COG2072	flavoprotein involved in K transport
IMCC20628_RS00380	COG1737	Transcriptional regulator
IMCC20628_RS00385	COG1116	anion transmembrane transporter activity
IMCC20628_RS00400	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS00405	COG3964	amidohydrolase
IMCC20628_RS00420	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS00435	COG0251	oxidation-reduction process
IMCC20628_RS00440	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00445	COG1454	alcohol dehydrogenase
IMCC20628_RS00460	COG2086	electron transfer activity
IMCC20628_RS00470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC20628_RS00480	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS00485	COG0702	epimerase
IMCC20628_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00525	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS00540	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00560	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS00565	COG1309	transcriptional regulator
IMCC20628_RS00575	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00615	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS00620	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS00640	COG2030	dehydratase
IMCC20628_RS00645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC20628_RS00655	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS00700	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC20628_RS00705	COG1802	Transcriptional regulator
IMCC20628_RS00715	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC20628_RS00765	COG0753	catalase activity
IMCC20628_RS00775	COG4993	Dehydrogenase
IMCC20628_RS00780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC20628_RS00780	COG2010	Cytochrome c
IMCC20628_RS00785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC20628_RS00805	COG1285	pathogenesis
IMCC20628_RS00810	COG0531	amino acid
IMCC20628_RS00835	COG1979	alcohol dehydrogenase
IMCC20628_RS00840	COG2130	NADP-dependent
IMCC20628_RS00855	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC20628_RS00875	COG1802	Transcriptional regulator
IMCC20628_RS00880	COG1802	Transcriptional regulator
IMCC20628_RS00890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC20628_RS00895	COG0625	glutathione transferase activity
IMCC20628_RS00950	COG0625	glutathione transferase activity
IMCC20628_RS00955	COG0625	glutathione transferase activity
IMCC20628_RS00960	COG1802	Transcriptional regulator
IMCC20628_RS00965	COG0277	FAD linked oxidase domain protein
IMCC20628_RS00965	COG0247	lactate metabolic process
IMCC20628_RS00970	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMCC20628_RS00975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS00985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS00985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMCC20628_RS00990	COG1024	Enoyl-CoA hydratase
IMCC20628_RS00995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC20628_RS01005	COG5001	Diguanylate cyclase
IMCC20628_RS01005	COG3300	MHYT domain
IMCC20628_RS01020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IMCC20628_RS01025	COG1215	transferase activity, transferring glycosyl groups
IMCC20628_RS01030	COG3769	mannosylglycerate metabolic process
IMCC20628_RS01040	COG0667	Aldo Keto reductase
IMCC20628_RS01045	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC20628_RS01055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMCC20628_RS01060	COG3842	ATPase activity
IMCC20628_RS01065	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS01070	COG1177	transmembrane transport
IMCC20628_RS01080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS01105	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS01130	COG0667	Aldo Keto reductase
IMCC20628_RS01150	COG0512	Glutamine amidotransferase of anthranilate synthase
IMCC20628_RS01150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC20628_RS01180	COG4176	ABC-type proline glycine betaine transport system permease component
IMCC20628_RS01185	COG0517	IMP dehydrogenase activity
IMCC20628_RS01185	COG4175	Glycine betaine
IMCC20628_RS01190	COG2113	Glycine betaine
IMCC20628_RS01195	COG1349	DNA-binding transcription factor activity
IMCC20628_RS01210	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS01220	COG3842	ATPase activity
IMCC20628_RS01245	COG1175	transmembrane transport
IMCC20628_RS01260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC20628_RS01270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMCC20628_RS01280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IMCC20628_RS01300	COG1805	sodium ion transport
IMCC20628_RS01310	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IMCC20628_RS01315	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IMCC20628_RS01320	COG2871	sodium ion transport
IMCC20628_RS01330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IMCC20628_RS01330	COG0617	tRNA 3'-terminal CCA addition
IMCC20628_RS01330	COG0517	IMP dehydrogenase activity
IMCC20628_RS01355	COG3845	ABC transporter
IMCC20628_RS01360	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS01365	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS01370	COG0402	S-adenosylhomocysteine deaminase activity
IMCC20628_RS01380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMCC20628_RS01385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC20628_RS01390	COG1609	Transcriptional regulator
IMCC20628_RS01395	COG1070	Carbohydrate kinase
IMCC20628_RS01400	COG2115	Belongs to the xylose isomerase family
IMCC20628_RS01405	COG2267	carboxylic ester hydrolase activity
IMCC20628_RS01420	COG3938	Belongs to the proline racemase family
IMCC20628_RS01425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS01430	COG1054	Belongs to the UPF0176 family
IMCC20628_RS01435	COG0800	Aldolase
IMCC20628_RS01455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS01465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS01500	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IMCC20628_RS01510	COG0583	DNA-binding transcription factor activity
IMCC20628_RS01545	COG0523	cobalamin synthesis protein
IMCC20628_RS01550	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IMCC20628_RS01565	COG1609	Transcriptional regulator
IMCC20628_RS01575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMCC20628_RS01580	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC20628_RS01595	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS01605	COG5001	Diguanylate cyclase
IMCC20628_RS01645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IMCC20628_RS01650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS01665	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC20628_RS01665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC20628_RS01685	COG0033	Phosphoglucomutase
IMCC20628_RS01690	COG0297	glycogen (starch) synthase activity
IMCC20628_RS01695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMCC20628_RS01700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMCC20628_RS01705	COG0058	SHG alpha-glucan phosphorylase activity
IMCC20628_RS01720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMCC20628_RS01725	COG4120	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS01755	COG0483	inositol monophosphate 1-phosphatase activity
IMCC20628_RS01765	COG0071	Belongs to the small heat shock protein (HSP20) family
IMCC20628_RS01780	COG3220	belongs to the UPF0276 family
IMCC20628_RS01795	COG0070	glutamate synthase
IMCC20628_RS01795	COG0067	glutamate synthase
IMCC20628_RS01795	COG0069	glutamate synthase activity
IMCC20628_RS01800	COG0393	Putative heavy-metal-binding
IMCC20628_RS01815	COG2951	lytic endotransglycosylase activity
IMCC20628_RS01820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMCC20628_RS01835	COG1585	Membrane protein implicated in regulation of membrane protease activity
IMCC20628_RS01840	COG0330	HflC and HflK could
IMCC20628_RS01845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IMCC20628_RS01850	COG0737	Belongs to the 5'-nucleotidase family
IMCC20628_RS01865	COG5310	Homospermidine synthase
IMCC20628_RS01885	COG3750	Belongs to the UPF0335 family
IMCC20628_RS01900	COG0469	pyruvate kinase activity
IMCC20628_RS01905	COG2267	carboxylic ester hydrolase activity
IMCC20628_RS01910	COG0457	Tetratricopeptide repeat
IMCC20628_RS01915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMCC20628_RS01920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMCC20628_RS01940	COG0640	Transcriptional regulator
IMCC20628_RS01945	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS01955	COG0352	thiamine-phosphate diphosphorylase activity
IMCC20628_RS01970	COG0483	inositol monophosphate 1-phosphatase activity
IMCC20628_RS01995	COG1132	(ABC) transporter
IMCC20628_RS02000	COG0254	rRNA binding
IMCC20628_RS02015	COG3321	synthase
IMCC20628_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS02015	COG0604	alcohol dehydrogenase
IMCC20628_RS02030	COG3588	fructose-bisphosphate aldolase
IMCC20628_RS02035	COG0126	phosphoglycerate kinase activity
IMCC20628_RS02095	COG1692	metallophosphoesterase
IMCC20628_RS02115	COG0217	transcriptional regulatory protein
IMCC20628_RS02120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC20628_RS02125	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IMCC20628_RS02130	COG0632	four-way junction helicase activity
IMCC20628_RS02135	COG2002	toxin-antitoxin pair type II binding
IMCC20628_RS02145	COG2255	four-way junction helicase activity
IMCC20628_RS02170	COG0824	Thioesterase
IMCC20628_RS02175	COG0024	Methionine aminopeptidase
IMCC20628_RS02185	COG0848	biopolymer transport protein
IMCC20628_RS02195	COG0823	Involved in the tonB-independent uptake of proteins
IMCC20628_RS02200	COG2885	chlorophyll binding
IMCC20628_RS02210	COG0037	tRNA processing
IMCC20628_RS02215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS02220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC20628_RS02245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC20628_RS02265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMCC20628_RS02280	COG3300	MHYT domain
IMCC20628_RS02280	COG5001	Diguanylate cyclase
IMCC20628_RS02310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC20628_RS02315	COG0564	pseudouridine synthase activity
IMCC20628_RS02375	COG0482	sulfurtransferase activity
IMCC20628_RS02380	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS02395	COG3415	Transposase
IMCC20628_RS02395	COG2801	Transposase and inactivated derivatives
IMCC20628_RS02405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMCC20628_RS02425	COG2801	Transposase and inactivated derivatives
IMCC20628_RS02430	COG2963	transposase activity
IMCC20628_RS02440	COG5001	Diguanylate cyclase
IMCC20628_RS02455	COG3415	Transposase
IMCC20628_RS02455	COG2801	Transposase and inactivated derivatives
IMCC20628_RS02470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC20628_RS02485	COG1175	transmembrane transport
IMCC20628_RS02490	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS02495	COG3842	ATPase activity
IMCC20628_RS02505	COG3254	rhamnose metabolic process
IMCC20628_RS02510	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS02520	COG2721	sulfolactate sulfo-lyase activity
IMCC20628_RS02525	COG2721	sulfolactate sulfo-lyase activity
IMCC20628_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS02535	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC20628_RS02555	COG2706	6-phosphogluconolactonase activity
IMCC20628_RS02560	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS02570	COG1129	ABC transporter
IMCC20628_RS02575	COG1129	ABC transporter
IMCC20628_RS02585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC20628_RS02595	COG1904	glucuronate isomerase
IMCC20628_RS02600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS02615	COG1917	Cupin 2, conserved barrel domain protein
IMCC20628_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS02630	COG0246	Mannitol dehydrogenase
IMCC20628_RS02635	COG1312	Catalyzes the dehydration of D-mannonate
IMCC20628_RS02640	COG1522	sequence-specific DNA binding
IMCC20628_RS02650	COG1115	amino acid carrier protein
IMCC20628_RS02660	COG0583	DNA-binding transcription factor activity
IMCC20628_RS02705	COG1744	ABC transporter substrate-binding protein PnrA-like
IMCC20628_RS02710	COG3845	ABC transporter
IMCC20628_RS02715	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS02720	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS02730	COG0438	transferase activity, transferring glycosyl groups
IMCC20628_RS02745	COG0642	Histidine kinase
IMCC20628_RS02775	COG0489	protein tyrosine kinase activity
IMCC20628_RS02785	COG1959	2 iron, 2 sulfur cluster binding
IMCC20628_RS02790	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC20628_RS02790	COG1902	pentaerythritol trinitrate reductase activity
IMCC20628_RS02795	COG0366	Alpha amylase catalytic
IMCC20628_RS02805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMCC20628_RS02815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS02820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS02870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC20628_RS02875	COG1309	transcriptional regulator
IMCC20628_RS02895	COG0431	NADPH-dependent FMN reductase
IMCC20628_RS02925	COG0493	'glutamate synthase
IMCC20628_RS02965	COG3448	diguanylate cyclase activity
IMCC20628_RS02965	COG4175	Glycine betaine
IMCC20628_RS02970	COG4176	ABC-type proline glycine betaine transport system permease component
IMCC20628_RS02980	COG1435	thymidine kinase activity
IMCC20628_RS03020	COG2197	response regulator
IMCC20628_RS03040	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IMCC20628_RS03060	COG0469	pyruvate kinase activity
IMCC20628_RS03075	COG0671	phosphoesterase, PA-phosphatase related
IMCC20628_RS03100	COG0512	Glutamine amidotransferase of anthranilate synthase
IMCC20628_RS03100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC20628_RS03110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMCC20628_RS03125	COG0513	Belongs to the DEAD box helicase family
IMCC20628_RS03130	COG0740	serine-type endopeptidase activity
IMCC20628_RS03135	COG1162	GTPase activity
IMCC20628_RS03140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMCC20628_RS03145	COG3706	GGDEF domain
IMCC20628_RS03160	COG0019	diaminopimelate decarboxylase activity
IMCC20628_RS03185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC20628_RS03205	COG0494	nUDIX hydrolase
IMCC20628_RS03230	COG1131	(ABC) transporter
IMCC20628_RS03235	COG0842	Transport permease protein
IMCC20628_RS03240	COG0435	Glutathione S-transferase
IMCC20628_RS03250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMCC20628_RS03260	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IMCC20628_RS03280	COG0714	Associated with various cellular activities
IMCC20628_RS03295	COG0617	tRNA 3'-terminal CCA addition
IMCC20628_RS03315	COG3842	ATPase activity
IMCC20628_RS03325	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC20628_RS03330	COG0408	coproporphyrinogen oxidase activity
IMCC20628_RS03340	COG0789	Transcriptional regulator
IMCC20628_RS03350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMCC20628_RS03355	COG1132	(ABC) transporter
IMCC20628_RS03360	COG1132	(ABC) transporter
IMCC20628_RS03375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IMCC20628_RS03375	COG2857	Cytochrome c1
IMCC20628_RS03380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMCC20628_RS03395	COG4774	siderophore transport
IMCC20628_RS03400	COG3128	pkhd-type hydroxylase
IMCC20628_RS03410	COG0848	biopolymer transport protein
IMCC20628_RS03440	COG0012	GTP binding
IMCC20628_RS03450	COG0193	aminoacyl-tRNA hydrolase activity
IMCC20628_RS03455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMCC20628_RS03465	COG2059	Chromate
IMCC20628_RS03470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMCC20628_RS03480	COG0006	proline dipeptidase activity
IMCC20628_RS03485	COG1496	oxidoreductase activity
IMCC20628_RS03495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMCC20628_RS03515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC20628_RS03525	COG2205	protein histidine kinase activity
IMCC20628_RS03530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC20628_RS03545	COG0154	amidase activity
IMCC20628_RS03550	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS03555	COG1846	Transcriptional regulator
IMCC20628_RS03560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC20628_RS03575	COG1522	sequence-specific DNA binding
IMCC20628_RS03580	COG0668	transmembrane transport
IMCC20628_RS03585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC20628_RS03595	COG1278	Cold shock
IMCC20628_RS03635	COG2133	pyrroloquinoline quinone binding
IMCC20628_RS03655	COG0436	Aminotransferase
IMCC20628_RS03665	COG1597	lipid kinase activity
IMCC20628_RS03675	COG1595	DNA-templated transcription, initiation
IMCC20628_RS03680	COG0583	DNA-binding transcription factor activity
IMCC20628_RS03685	COG0492	ferredoxin-NADP+ reductase activity
IMCC20628_RS03690	COG1522	sequence-specific DNA binding
IMCC20628_RS03700	COG0438	transferase activity, transferring glycosyl groups
IMCC20628_RS03705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC20628_RS03745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMCC20628_RS03760	COG0477	Major facilitator Superfamily
IMCC20628_RS03780	COG2321	neutral zinc metallopeptidase
IMCC20628_RS03785	COG3264	Mechanosensitive ion channel
IMCC20628_RS03785	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IMCC20628_RS03790	COG0534	Mate efflux family protein
IMCC20628_RS03795	COG3119	arylsulfatase activity
IMCC20628_RS03810	COG0505	Belongs to the CarA family
IMCC20628_RS03820	COG0358	DNA primase activity
IMCC20628_RS03825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC20628_RS03855	COG0625	glutathione transferase activity
IMCC20628_RS03865	COG4221	oxidoreductase activity
IMCC20628_RS03910	COG2968	Membrane
IMCC20628_RS03930	COG2801	Transposase and inactivated derivatives
IMCC20628_RS03930	COG3415	Transposase
IMCC20628_RS03960	COG1609	Transcriptional regulator
IMCC20628_RS03970	COG1175	transmembrane transport
IMCC20628_RS03975	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS03985	COG3842	ATPase activity
IMCC20628_RS03990	COG3842	ATPase activity
IMCC20628_RS04005	COG1309	transcriptional regulator
IMCC20628_RS04010	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC20628_RS04020	COG1178	ABC-type Fe3 transport system permease component
IMCC20628_RS04045	COG0028	Belongs to the TPP enzyme family
IMCC20628_RS04050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC20628_RS04055	COG2267	carboxylic ester hydrolase activity
IMCC20628_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS04105	COG2226	methyltransferase
IMCC20628_RS04115	COG0154	amidase activity
IMCC20628_RS04130	COG2323	membrane
IMCC20628_RS04140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS04145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMCC20628_RS04150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS04175	COG5001	Diguanylate cyclase
IMCC20628_RS04175	COG3300	MHYT domain
IMCC20628_RS04190	COG0667	Aldo Keto reductase
IMCC20628_RS04195	COG0697	spore germination
IMCC20628_RS04200	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IMCC20628_RS04205	COG3023	N-Acetylmuramoyl-L-alanine amidase
IMCC20628_RS04225	COG3685	Protein conserved in bacteria
IMCC20628_RS04235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMCC20628_RS04255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS04270	COG2001	Belongs to the MraZ family
IMCC20628_RS04275	COG0275	rRNA processing
IMCC20628_RS04290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMCC20628_RS04300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC20628_RS04305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMCC20628_RS04315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC20628_RS04320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMCC20628_RS04345	COG3300	MHYT domain
IMCC20628_RS04345	COG5001	Diguanylate cyclase
IMCC20628_RS04355	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMCC20628_RS04360	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMCC20628_RS04365	COG0849	cell division
IMCC20628_RS04370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMCC20628_RS04385	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMCC20628_RS04390	COG0497	DNA recombination
IMCC20628_RS04400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC20628_RS04415	COG0306	phosphate transporter
IMCC20628_RS04445	COG0604	alcohol dehydrogenase
IMCC20628_RS04460	COG2264	protein methyltransferase activity
IMCC20628_RS04470	COG1999	signal sequence binding
IMCC20628_RS04480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMCC20628_RS04490	COG0405	Gamma-glutamyltransferase
IMCC20628_RS04495	COG2738	Putative neutral zinc metallopeptidase
IMCC20628_RS04500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMCC20628_RS04515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC20628_RS04540	COG0556	nucleotide-excision repair
IMCC20628_RS04605	COG0384	phenazine biosynthesis protein PhzF
IMCC20628_RS04620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC20628_RS04680	COG2801	Transposase and inactivated derivatives
IMCC20628_RS04680	COG3415	Transposase
IMCC20628_RS04705	COG2721	sulfolactate sulfo-lyase activity
IMCC20628_RS04710	COG2721	sulfolactate sulfo-lyase activity
IMCC20628_RS04715	COG2186	Transcriptional regulator
IMCC20628_RS04720	COG1063	alcohol dehydrogenase
IMCC20628_RS04725	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS04730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMCC20628_RS04730	COG0473	3-isopropylmalate dehydrogenase activity
IMCC20628_RS04735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS04745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS04765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS04775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMCC20628_RS04775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS04795	COG0363	glucosamine-6-phosphate deaminase activity
IMCC20628_RS04805	COG0165	Argininosuccinate lyase
IMCC20628_RS04810	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC20628_RS04820	COG1177	transmembrane transport
IMCC20628_RS04840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS04845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMCC20628_RS04850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS04865	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC20628_RS04880	COG1732	Glycine betaine
IMCC20628_RS04885	COG1174	glycine betaine transport
IMCC20628_RS04890	COG1125	glycine betaine transport
IMCC20628_RS04895	COG1174	glycine betaine transport
IMCC20628_RS04910	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS04950	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS04955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC20628_RS04980	COG3264	Mechanosensitive ion channel
IMCC20628_RS04980	COG1511	domain protein
IMCC20628_RS05020	COG0583	DNA-binding transcription factor activity
IMCC20628_RS05045	COG1410	methionine synthase
IMCC20628_RS05045	COG0646	methionine synthase
IMCC20628_RS05080	COG5012	cobalamin binding
IMCC20628_RS05105	COG1595	DNA-templated transcription, initiation
IMCC20628_RS05110	COG2304	oxidoreductase activity
IMCC20628_RS05120	COG0646	methionine synthase
IMCC20628_RS05120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMCC20628_RS05125	COG4175	Glycine betaine
IMCC20628_RS05125	COG0517	IMP dehydrogenase activity
IMCC20628_RS05130	COG4176	ABC-type proline glycine betaine transport system permease component
IMCC20628_RS05245	COG2875	Belongs to the precorrin methyltransferase family
IMCC20628_RS05255	COG2099	Precorrin-6x reductase
IMCC20628_RS05300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMCC20628_RS05310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMCC20628_RS05315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC20628_RS05320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMCC20628_RS05345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMCC20628_RS05350	COG3706	GGDEF domain
IMCC20628_RS05350	COG5001	Diguanylate cyclase
IMCC20628_RS05350	COG2203	Gaf domain
IMCC20628_RS05350	COG4251	negative regulation of phosphorylation
IMCC20628_RS05355	COG0625	glutathione transferase activity
IMCC20628_RS05370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC20628_RS05385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC20628_RS05395	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS05405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC20628_RS05410	COG0183	Belongs to the thiolase family
IMCC20628_RS05415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IMCC20628_RS05420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMCC20628_RS05425	COG3485	protocatechuate 3,4-dioxygenase
IMCC20628_RS05430	COG3485	protocatechuate 3,4-dioxygenase
IMCC20628_RS05435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMCC20628_RS05440	COG0583	DNA-binding transcription factor activity
IMCC20628_RS05470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMCC20628_RS05480	COG3842	ATPase activity
IMCC20628_RS05485	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS05490	COG1177	transmembrane transport
IMCC20628_RS05505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC20628_RS05525	COG2226	methyltransferase
IMCC20628_RS05530	COG1309	transcriptional regulator
IMCC20628_RS05545	COG3842	ATPase activity
IMCC20628_RS05550	COG1177	transmembrane transport
IMCC20628_RS05560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC20628_RS05565	COG4638	Rieske (2fe-2S)
IMCC20628_RS05570	COG0436	Aminotransferase
IMCC20628_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC20628_RS05590	COG0765	amino acid transport
IMCC20628_RS05595	COG0765	amino acid transport
IMCC20628_RS05605	COG3842	ATPase activity
IMCC20628_RS05610	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS05620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC20628_RS05635	COG4974	Belongs to the 'phage' integrase family
IMCC20628_RS05655	COG3047	cAMP biosynthetic process
IMCC20628_RS05655	COG2885	chlorophyll binding
IMCC20628_RS05660	COG3743	rRNA binding
IMCC20628_RS05660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC20628_RS05670	COG0741	lytic transglycosylase activity
IMCC20628_RS05675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC20628_RS05680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMCC20628_RS05690	COG1758	RNA polymerase activity
IMCC20628_RS05705	COG0736	holo-[acyl-carrier-protein] synthase activity
IMCC20628_RS05710	COG0681	Belongs to the peptidase S26 family
IMCC20628_RS05715	COG0571	ribonuclease III activity
IMCC20628_RS05720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMCC20628_RS05725	COG1381	Involved in DNA repair and RecF pathway recombination
IMCC20628_RS05745	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMCC20628_RS05750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IMCC20628_RS05765	COG0679	Auxin Efflux Carrier
IMCC20628_RS05780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IMCC20628_RS05785	COG0354	folic acid binding
IMCC20628_RS05810	COG1410	methionine synthase
IMCC20628_RS05810	COG0646	methionine synthase
IMCC20628_RS05830	COG0577	efflux transmembrane transporter activity
IMCC20628_RS05830	COG1136	(ABC) transporter
IMCC20628_RS05845	COG0215	cysteine-tRNA ligase activity
IMCC20628_RS05850	COG2852	Protein conserved in bacteria
IMCC20628_RS05880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC20628_RS05890	COG1611	Belongs to the LOG family
IMCC20628_RS05900	COG0640	Transcriptional regulator
IMCC20628_RS05905	COG5265	(ABC) transporter
IMCC20628_RS05910	COG0688	phosphatidylethanolamine metabolic process
IMCC20628_RS05915	COG1183	phosphatidylcholine synthase activity
IMCC20628_RS05925	COG4221	oxidoreductase activity
IMCC20628_RS05930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMCC20628_RS05945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMCC20628_RS05955	COG1335	isochorismatase
IMCC20628_RS06005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC20628_RS06030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMCC20628_RS06060	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS06075	COG0702	epimerase
IMCC20628_RS06090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS06095	COG4311	Sarcosine oxidase, delta subunit
IMCC20628_RS06100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC20628_RS06100	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC20628_RS06140	COG2423	ornithine cyclodeaminase activity
IMCC20628_RS06145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC20628_RS06200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMCC20628_RS06205	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC20628_RS06210	COG3396	Phenylacetate-CoA oxygenase
IMCC20628_RS06215	COG3460	Phenylacetate-CoA oxygenase
IMCC20628_RS06220	COG3396	Phenylacetate-CoA oxygenase
IMCC20628_RS06255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS06265	COG0702	epimerase
IMCC20628_RS06275	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS06295	COG2030	dehydratase
IMCC20628_RS06295	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS06300	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC20628_RS06300	COG1024	Enoyl-CoA hydratase
IMCC20628_RS06305	COG1024	Enoyl-CoA hydratase
IMCC20628_RS06310	COG2050	protein possibly involved in aromatic compounds catabolism
IMCC20628_RS06325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC20628_RS06340	COG2358	TRAP transporter, solute receptor (TAXI family
IMCC20628_RS06360	COG0583	DNA-binding transcription factor activity
IMCC20628_RS06370	COG2072	flavoprotein involved in K transport
IMCC20628_RS06375	COG0385	Bile acid
IMCC20628_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS06390	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS06405	COG1131	(ABC) transporter
IMCC20628_RS06410	COG0842	Transport permease protein
IMCC20628_RS06410	COG1129	ABC transporter
IMCC20628_RS06435	COG2194	sulfuric ester hydrolase activity
IMCC20628_RS06480	COG0659	secondary active sulfate transmembrane transporter activity
IMCC20628_RS06485	COG4717	serine-type aminopeptidase activity
IMCC20628_RS06490	COG0420	3'-5' exonuclease activity
IMCC20628_RS06505	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS06510	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS06545	COG2391	methyltransferase activity
IMCC20628_RS06560	COG0785	Cytochrome C biogenesis protein
IMCC20628_RS06590	COG0737	Belongs to the 5'-nucleotidase family
IMCC20628_RS06595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMCC20628_RS06610	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC20628_RS06615	COG0725	ABC transporter, periplasmic molybdate-binding protein
IMCC20628_RS06620	COG4149	molybdate abc transporter
IMCC20628_RS06625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IMCC20628_RS06630	COG0583	DNA-binding transcription factor activity
IMCC20628_RS06635	COG2175	clavaminate synthase activity
IMCC20628_RS06645	COG4106	trans-aconitate 2-methyltransferase activity
IMCC20628_RS06660	COG2188	Transcriptional regulator
IMCC20628_RS06665	COG3624	Phosphonate C-P lyase system protein PhnG
IMCC20628_RS06670	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IMCC20628_RS06675	COG3626	phosphonate metabolism
IMCC20628_RS06680	COG3627	carbon phosphorus lyase activity
IMCC20628_RS06685	COG4107	phosphonate C-P lyase system protein PhnK
IMCC20628_RS06690	COG4778	phosphonate C-P lyase system protein PhnL
IMCC20628_RS06700	COG0778	Nitroreductase
IMCC20628_RS06705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IMCC20628_RS06715	COG3639	organic phosphonate transmembrane transporter activity
IMCC20628_RS06720	COG3639	organic phosphonate transmembrane transporter activity
IMCC20628_RS06725	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IMCC20628_RS06730	COG3454	Phosphonate metabolism
IMCC20628_RS06735	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IMCC20628_RS06770	COG0657	acetylesterase activity
IMCC20628_RS06785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS06815	COG0346	lactoylglutathione lyase activity
IMCC20628_RS06825	COG1233	COG1233 Phytoene dehydrogenase and related
IMCC20628_RS06830	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IMCC20628_RS06835	COG1233	COG1233 Phytoene dehydrogenase and related
IMCC20628_RS06845	COG0601	transmembrane transport
IMCC20628_RS06850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS06855	COG0444	Belongs to the ABC transporter superfamily
IMCC20628_RS06885	COG1024	Enoyl-CoA hydratase
IMCC20628_RS06890	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS06910	COG3483	tryptophan 2,3-dioxygenase activity
IMCC20628_RS06935	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS06955	COG0693	protein deglycase activity
IMCC20628_RS06960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMCC20628_RS06975	COG1126	abc transporter atp-binding protein
IMCC20628_RS07000	COG0730	response to heat
IMCC20628_RS07020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IMCC20628_RS07025	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IMCC20628_RS07040	COG0625	glutathione transferase activity
IMCC20628_RS07045	COG1573	uracil-dna glycosylase
IMCC20628_RS07050	COG1522	sequence-specific DNA binding
IMCC20628_RS07065	COG2084	Dehydrogenase
IMCC20628_RS07085	COG1132	(ABC) transporter
IMCC20628_RS07110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC20628_RS07115	COG2814	Major facilitator Superfamily
IMCC20628_RS07130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMCC20628_RS07155	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS07160	COG2203	Gaf domain
IMCC20628_RS07160	COG3706	GGDEF domain
IMCC20628_RS07160	COG4251	negative regulation of phosphorylation
IMCC20628_RS07160	COG5001	Diguanylate cyclase
IMCC20628_RS07165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMCC20628_RS07165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMCC20628_RS07170	COG0798	PFAM Bile acid sodium symporter
IMCC20628_RS07185	COG2223	nitrite transmembrane transporter activity
IMCC20628_RS07190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IMCC20628_RS07195	COG1140	nitrate reductase beta subunit
IMCC20628_RS07200	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IMCC20628_RS07205	COG2181	nitrate reductase activity
IMCC20628_RS07215	COG1618	nucleotide phosphatase activity, acting on free nucleotides
IMCC20628_RS07215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IMCC20628_RS07230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC20628_RS07230	COG0574	Belongs to the PEP-utilizing enzyme family
IMCC20628_RS07235	COG1011	Hydrolase
IMCC20628_RS07245	COG3639	organic phosphonate transmembrane transporter activity
IMCC20628_RS07250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IMCC20628_RS07260	COG1129	ABC transporter
IMCC20628_RS07275	COG1609	Transcriptional regulator
IMCC20628_RS07325	COG0701	Predicted permease
IMCC20628_RS07330	COG0640	Transcriptional regulator
IMCC20628_RS07335	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS07345	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS07350	COG3962	Belongs to the TPP enzyme family
IMCC20628_RS07360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC20628_RS07375	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS07410	COG3916	Acyl-homoserine-lactone synthase
IMCC20628_RS07415	COG2197	response regulator
IMCC20628_RS07420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC20628_RS07425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMCC20628_RS07435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC20628_RS07440	COG0183	Belongs to the thiolase family
IMCC20628_RS07455	COG0659	secondary active sulfate transmembrane transporter activity
IMCC20628_RS07460	COG3273	potassium ion transport
IMCC20628_RS07460	COG0471	metal ion transport
IMCC20628_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS07480	COG1802	Transcriptional regulator
IMCC20628_RS07495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS07495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMCC20628_RS07515	COG0546	phosphoglycolate phosphatase activity
IMCC20628_RS07520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMCC20628_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS07575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IMCC20628_RS07585	COG3384	dioxygenase
IMCC20628_RS07610	COG0281	malic enzyme
IMCC20628_RS07610	COG0280	phosphate acetyltransferase
IMCC20628_RS07615	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC20628_RS07620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IMCC20628_RS07625	COG1127	ABC transporter
IMCC20628_RS07635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IMCC20628_RS07635	COG3218	ABC-type transport auxiliary lipoprotein component
IMCC20628_RS07660	COG0633	Ferredoxin
IMCC20628_RS07665	COG0492	ferredoxin-NADP+ reductase activity
IMCC20628_RS07675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMCC20628_RS07685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMCC20628_RS07695	COG3768	UPF0283 membrane protein
IMCC20628_RS07700	COG3106	COG3106 Predicted ATPase
IMCC20628_RS07725	COG2885	chlorophyll binding
IMCC20628_RS07735	COG2313	pseudouridylate synthase activity
IMCC20628_RS07745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMCC20628_RS07750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC20628_RS07775	COG0538	isocitrate dehydrogenase activity
IMCC20628_RS07780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMCC20628_RS07785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMCC20628_RS07825	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMCC20628_RS07830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC20628_RS07835	COG2066	Belongs to the glutaminase family
IMCC20628_RS07840	COG0037	tRNA processing
IMCC20628_RS07845	COG0483	inositol monophosphate 1-phosphatase activity
IMCC20628_RS07865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IMCC20628_RS07895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC20628_RS07905	COG0492	ferredoxin-NADP+ reductase activity
IMCC20628_RS07925	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMCC20628_RS07950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC20628_RS07960	COG3191	aminopeptidase activity
IMCC20628_RS07970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMCC20628_RS07975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMCC20628_RS07990	COG3608	succinylglutamate desuccinylase aspartoacylase
IMCC20628_RS07990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMCC20628_RS07995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC20628_RS08010	COG0300	oxidoreductase activity
IMCC20628_RS08020	COG0583	DNA-binding transcription factor activity
IMCC20628_RS08025	COG0513	Belongs to the DEAD box helicase family
IMCC20628_RS08030	COG0739	heme binding
IMCC20628_RS08035	COG2833	Protein of unknown function (DUF455)
IMCC20628_RS08040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMCC20628_RS08050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMCC20628_RS08055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IMCC20628_RS08060	COG0628	permease
IMCC20628_RS08085	COG3547	Transposase (IS116 IS110 IS902 family)
IMCC20628_RS08105	COG2801	Transposase and inactivated derivatives
IMCC20628_RS08125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC20628_RS08130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC20628_RS08135	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC20628_RS08140	COG0649	NAD binding
IMCC20628_RS08145	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IMCC20628_RS08150	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMCC20628_RS08155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC20628_RS08155	COG3743	rRNA binding
IMCC20628_RS08165	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC20628_RS08170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC20628_RS08195	COG1007	ATP synthesis coupled electron transport
IMCC20628_RS08210	COG0346	lactoylglutathione lyase activity
IMCC20628_RS08225	COG0442	prolyl-tRNA aminoacylation
IMCC20628_RS08235	COG1136	(ABC) transporter
IMCC20628_RS08245	COG2945	thiolester hydrolase activity
IMCC20628_RS08250	COG1104	cysteine desulfurase activity
IMCC20628_RS08255	COG0719	Fe-S assembly protein
IMCC20628_RS08265	COG0396	ATPase activity
IMCC20628_RS08270	COG0719	Fe-S assembly protein
IMCC20628_RS08275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMCC20628_RS08280	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC20628_RS08285	COG0316	Belongs to the HesB IscA family
IMCC20628_RS08300	COG0729	surface antigen
IMCC20628_RS08315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC20628_RS08335	COG2824	Alkylphosphonate utilization operon protein PhnA
IMCC20628_RS08365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMCC20628_RS08375	COG0840	transmembrane signaling receptor activity
IMCC20628_RS08385	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IMCC20628_RS08400	COG1058	Belongs to the CinA family
IMCC20628_RS08400	COG1546	Belongs to the CinA family
IMCC20628_RS08405	COG0655	NAD(P)H dehydrogenase (quinone) activity
IMCC20628_RS08425	COG0784	Response regulator, receiver
IMCC20628_RS08435	COG2202	Pas domain
IMCC20628_RS08435	COG3920	Histidine kinase
IMCC20628_RS08450	COG3237	CsbD-like
IMCC20628_RS08465	COG0628	permease
IMCC20628_RS08490	COG0840	transmembrane signaling receptor activity
IMCC20628_RS08495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMCC20628_RS08500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMCC20628_RS08520	COG0737	Belongs to the 5'-nucleotidase family
IMCC20628_RS08545	COG2375	cellular response to nickel ion
IMCC20628_RS08550	COG1522	sequence-specific DNA binding
IMCC20628_RS08555	COG0686	Belongs to the AlaDH PNT family
IMCC20628_RS08570	COG2897	thiosulfate sulfurtransferase activity
IMCC20628_RS08580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC20628_RS08595	COG0300	oxidoreductase activity
IMCC20628_RS08600	COG2211	Major facilitator Superfamily
IMCC20628_RS08605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IMCC20628_RS08620	COG0415	Belongs to the DNA photolyase family
IMCC20628_RS08640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IMCC20628_RS08655	COG0525	valine-tRNA ligase activity
IMCC20628_RS08665	COG0129	dihydroxy-acid dehydratase activity
IMCC20628_RS08670	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IMCC20628_RS08685	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IMCC20628_RS08690	COG0018	arginyl-trna synthetase
IMCC20628_RS08700	COG1472	Belongs to the glycosyl hydrolase 3 family
IMCC20628_RS08705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMCC20628_RS08710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMCC20628_RS08715	COG3842	ATPase activity
IMCC20628_RS08720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMCC20628_RS08725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMCC20628_RS08730	COG0805	protein transport
IMCC20628_RS08740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IMCC20628_RS08745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IMCC20628_RS08760	COG1862	Preprotein translocase
IMCC20628_RS08795	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMCC20628_RS08860	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC20628_RS08875	COG2003	Belongs to the UPF0758 family
IMCC20628_RS08880	COG0024	Methionine aminopeptidase
IMCC20628_RS08885	COG1489	DNA binding
IMCC20628_RS08890	COG3243	poly(R)-hydroxyalkanoic acid synthase
IMCC20628_RS08900	COG0436	Aminotransferase
IMCC20628_RS08910	COG1494	fructose-1,6-bisphosphatase
IMCC20628_RS08915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMCC20628_RS08935	COG1278	Cold shock
IMCC20628_RS08965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS08970	COG0601	transmembrane transport
IMCC20628_RS08975	COG0747	negative chemotaxis
IMCC20628_RS08980	COG1349	DNA-binding transcription factor activity
IMCC20628_RS08995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC20628_RS09070	COG2801	Transposase and inactivated derivatives
IMCC20628_RS09070	COG3415	Transposase
IMCC20628_RS09110	COG2771	luxR family
IMCC20628_RS09120	COG4251	negative regulation of phosphorylation
IMCC20628_RS09125	COG0626	cystathionine gamma-synthase activity
IMCC20628_RS09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC20628_RS09135	COG4597	amino acid ABC transporter
IMCC20628_RS09140	COG0765	amino acid transport
IMCC20628_RS09145	COG1126	abc transporter atp-binding protein
IMCC20628_RS09165	COG2267	carboxylic ester hydrolase activity
IMCC20628_RS09225	COG0516	GMP reductase activity
IMCC20628_RS09225	COG0517	IMP dehydrogenase activity
IMCC20628_RS09230	COG1752	Esterase of the alpha-beta hydrolase superfamily
IMCC20628_RS09235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMCC20628_RS09240	COG0302	gtp cyclohydrolase
IMCC20628_RS09245	COG0822	iron-sulfur transferase activity
IMCC20628_RS09260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMCC20628_RS09265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMCC20628_RS09305	COG0187	DNA topoisomerase II activity
IMCC20628_RS09320	COG1088	dTDP-glucose 4,6-dehydratase activity
IMCC20628_RS09340	COG0174	glutamine synthetase
IMCC20628_RS09345	COG0347	Belongs to the P(II) protein family
IMCC20628_RS09355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMCC20628_RS09355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMCC20628_RS09365	COG2223	nitrite transmembrane transporter activity
IMCC20628_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS09380	COG0071	Belongs to the small heat shock protein (HSP20) family
IMCC20628_RS09385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMCC20628_RS09390	COG0629	single-stranded DNA binding
IMCC20628_RS09420	COG2095	MarC family integral membrane protein
IMCC20628_RS09425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC20628_RS09430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMCC20628_RS09435	COG2378	regulation of single-species biofilm formation
IMCC20628_RS09460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMCC20628_RS09475	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMCC20628_RS09480	COG0343	queuine tRNA-ribosyltransferase activity
IMCC20628_RS09495	COG2801	Transposase and inactivated derivatives
IMCC20628_RS09500	COG2963	transposase activity
IMCC20628_RS09515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC20628_RS09530	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS09555	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS09560	COG1024	Enoyl-CoA hydratase
IMCC20628_RS09575	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IMCC20628_RS09600	COG0625	glutathione transferase activity
IMCC20628_RS09605	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMCC20628_RS09610	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMCC20628_RS09620	COG0402	S-adenosylhomocysteine deaminase activity
IMCC20628_RS09625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS09660	COG0785	Cytochrome C biogenesis protein
IMCC20628_RS09665	COG0697	spore germination
IMCC20628_RS09670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC20628_RS09675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMCC20628_RS09685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMCC20628_RS09690	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IMCC20628_RS09695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMCC20628_RS09715	COG1923	regulation of RNA biosynthetic process
IMCC20628_RS09720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMCC20628_RS09740	COG3956	TIGRFAM MazG family protein
IMCC20628_RS09750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IMCC20628_RS09750	COG1648	precorrin-2 dehydrogenase activity
IMCC20628_RS09760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMCC20628_RS09775	COG0500	methyltransferase
IMCC20628_RS09780	COG1346	cytolysis
IMCC20628_RS09785	COG1380	Effector of murein hydrolase LrgA
IMCC20628_RS09790	COG1238	metal cluster binding
IMCC20628_RS09810	COG0640	Transcriptional regulator
IMCC20628_RS09820	COG0697	spore germination
IMCC20628_RS09825	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IMCC20628_RS09830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC20628_RS09835	COG5001	Diguanylate cyclase
IMCC20628_RS09835	COG3300	MHYT domain
IMCC20628_RS09840	COG1234	tRNA 3'-trailer cleavage
IMCC20628_RS09845	COG0084	hydrolase, TatD family'
IMCC20628_RS09850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC20628_RS09860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMCC20628_RS09865	COG1686	Belongs to the peptidase S11 family
IMCC20628_RS09870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMCC20628_RS09945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMCC20628_RS09965	COG1024	Enoyl-CoA hydratase
IMCC20628_RS09970	COG0183	Belongs to the thiolase family
IMCC20628_RS09975	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS09980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS09990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS10010	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS10010	COG3347	Dehydrogenase
IMCC20628_RS10015	COG2390	Transcriptional regulator
IMCC20628_RS10020	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IMCC20628_RS10035	COG3842	ATPase activity
IMCC20628_RS10045	COG1175	transmembrane transport
IMCC20628_RS10050	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS10060	COG2095	MarC family integral membrane protein
IMCC20628_RS10070	COG3415	Transposase
IMCC20628_RS10070	COG2801	Transposase and inactivated derivatives
IMCC20628_RS10090	COG4953	penicillin-binding protein 1C
IMCC20628_RS10095	COG2373	Large extracellular alpha-helical protein
IMCC20628_RS10100	COG0640	Transcriptional regulator
IMCC20628_RS10105	COG0156	8-amino-7-oxononanoate synthase activity
IMCC20628_RS10110	COG0174	glutamine synthetase
IMCC20628_RS10130	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS10135	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS10140	COG3845	ABC transporter
IMCC20628_RS10145	COG1183	phosphatidylcholine synthase activity
IMCC20628_RS10160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMCC20628_RS10165	COG0679	Auxin Efflux Carrier
IMCC20628_RS10180	COG4166	transmembrane transport
IMCC20628_RS10190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMCC20628_RS10195	COG0569	domain protein
IMCC20628_RS10200	COG2204	response regulator
IMCC20628_RS10205	COG5000	phosphorelay sensor kinase activity
IMCC20628_RS10210	COG2204	response regulator
IMCC20628_RS10215	COG3852	Histidine kinase
IMCC20628_RS10225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMCC20628_RS10225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC20628_RS10235	COG2867	negative regulation of translational initiation
IMCC20628_RS10240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMCC20628_RS10245	COG2261	transglycosylase associated protein
IMCC20628_RS10255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC20628_RS10275	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC20628_RS10280	COG0022	dehydrogenase e1 component
IMCC20628_RS10280	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC20628_RS10285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMCC20628_RS10295	COG0148	phosphopyruvate hydratase activity
IMCC20628_RS10300	COG0840	transmembrane signaling receptor activity
IMCC20628_RS10305	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IMCC20628_RS10315	COG1686	Belongs to the peptidase S11 family
IMCC20628_RS10345	COG0504	CTP synthase activity
IMCC20628_RS10355	COG0149	triose-phosphate isomerase activity
IMCC20628_RS10395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMCC20628_RS10400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC20628_RS10410	COG0315	cyclic pyranopterin monophosphate synthase activity
IMCC20628_RS10415	COG0303	'Molybdopterin
IMCC20628_RS10420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMCC20628_RS10425	COG0658	competence protein
IMCC20628_RS10425	COG2333	competence protein COMEC
IMCC20628_RS10430	COG0372	Belongs to the citrate synthase family
IMCC20628_RS10435	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMCC20628_RS10440	COG3494	Protein of unknown function (DUF1009)
IMCC20628_RS10445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMCC20628_RS10450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMCC20628_RS10455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMCC20628_RS10460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMCC20628_RS10465	COG0750	zinc metalloprotease
IMCC20628_RS10475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC20628_RS10480	COG0233	cytoplasmic translational termination
IMCC20628_RS10485	COG0528	UMP kinase activity
IMCC20628_RS10490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMCC20628_RS10495	COG0052	Belongs to the universal ribosomal protein uS2 family
IMCC20628_RS10515	COG0443	Heat shock 70 kDa protein
IMCC20628_RS10550	COG0537	adenosine 5'-monophosphoramidase activity
IMCC20628_RS10580	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IMCC20628_RS10590	COG1686	Belongs to the peptidase S11 family
IMCC20628_RS10595	COG0484	heat shock protein binding
IMCC20628_RS10615	COG1760	l-serine dehydratase
IMCC20628_RS10630	COG0697	spore germination
IMCC20628_RS10650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS10660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS10675	COG2239	Acts as a magnesium transporter
IMCC20628_RS10695	COG3842	ATPase activity
IMCC20628_RS10700	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC20628_RS10705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC20628_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS10725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMCC20628_RS10730	COG1283	sodium-dependent phosphate transmembrane transporter activity
IMCC20628_RS10745	COG1349	DNA-binding transcription factor activity
IMCC20628_RS10750	COG0129	dihydroxy-acid dehydratase activity
IMCC20628_RS10765	COG0321	lipoyl(octanoyl) transferase activity
IMCC20628_RS10775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IMCC20628_RS10780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IMCC20628_RS10805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMCC20628_RS10820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMCC20628_RS10830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMCC20628_RS10835	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IMCC20628_RS10840	COG0203	ribosomal protein L17
IMCC20628_RS10845	COG0202	RNA polymerase activity
IMCC20628_RS10850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMCC20628_RS10855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMCC20628_RS10860	COG0563	adenylate kinase activity
IMCC20628_RS10865	COG0201	protein transport
IMCC20628_RS10870	COG0200	Binds to the 23S rRNA
IMCC20628_RS10875	COG1841	ribosomal large subunit assembly
IMCC20628_RS10880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMCC20628_RS10885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMCC20628_RS10890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMCC20628_RS10895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMCC20628_RS10900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMCC20628_RS10905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMCC20628_RS10910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMCC20628_RS10915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMCC20628_RS10920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMCC20628_RS10925	COG0255	Belongs to the universal ribosomal protein uL29 family
IMCC20628_RS10930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMCC20628_RS10935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMCC20628_RS10940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMCC20628_RS10950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMCC20628_RS10960	COG0088	Forms part of the polypeptide exit tunnel
IMCC20628_RS10965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMCC20628_RS10970	COG0051	transcription antitermination factor activity, RNA binding
IMCC20628_RS10975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC20628_RS10980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMCC20628_RS10985	COG0049	tRNA binding
IMCC20628_RS10990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMCC20628_RS11010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMCC20628_RS11015	COG0085	RNA polymerase activity
IMCC20628_RS11020	COG0222	ribosome binding
IMCC20628_RS11030	COG0081	regulation of translation
IMCC20628_RS11035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMCC20628_RS11045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC20628_RS11065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC20628_RS11085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC20628_RS11100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC20628_RS11125	COG4176	ABC-type proline glycine betaine transport system permease component
IMCC20628_RS11145	COG1349	DNA-binding transcription factor activity
IMCC20628_RS11150	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS11155	COG1129	ABC transporter
IMCC20628_RS11175	COG3959	Transketolase, thiamine diphosphate binding domain
IMCC20628_RS11180	COG3958	Transketolase
IMCC20628_RS11185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC20628_RS11210	COG2217	Heavy metal translocating P-type atpase
IMCC20628_RS11215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMCC20628_RS11235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMCC20628_RS11240	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMCC20628_RS11245	COG1530	ribonuclease E activity
IMCC20628_RS11250	COG0436	Aminotransferase
IMCC20628_RS11265	COG0511	ligase activity, forming carbon-carbon bonds
IMCC20628_RS11270	COG0439	Biotin carboxylase
IMCC20628_RS11275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IMCC20628_RS11310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IMCC20628_RS11315	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC20628_RS11325	COG0456	acetyltransferase
IMCC20628_RS11325	COG0454	-acetyltransferase
IMCC20628_RS11335	COG3811	Belongs to the UPF0386 family
IMCC20628_RS11340	COG0154	amidase activity
IMCC20628_RS11345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC20628_RS11355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMCC20628_RS11360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMCC20628_RS11380	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS11385	COG0540	Belongs to the ATCase OTCase family
IMCC20628_RS11390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC20628_RS11395	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IMCC20628_RS11400	COG0758	DNA mediated transformation
IMCC20628_RS11410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMCC20628_RS11415	COG0557	exoribonuclease II activity
IMCC20628_RS11435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMCC20628_RS11445	COG0784	Response regulator, receiver
IMCC20628_RS11460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMCC20628_RS11475	COG0776	regulation of translation
IMCC20628_RS11480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMCC20628_RS11485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMCC20628_RS11490	COG0740	serine-type endopeptidase activity
IMCC20628_RS11510	COG2124	cytochrome p450
IMCC20628_RS11530	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS11535	COG5002	protein histidine kinase activity
IMCC20628_RS11545	COG1832	CoA-binding protein
IMCC20628_RS11570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMCC20628_RS11575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMCC20628_RS11580	COG0010	Belongs to the arginase family
IMCC20628_RS11595	COG1612	heme a metabolic process
IMCC20628_RS11690	COG0776	regulation of translation
IMCC20628_RS11695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC20628_RS11700	COG0416	fatty acid biosynthetic process
IMCC20628_RS11720	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IMCC20628_RS11725	COG2814	Major facilitator Superfamily
IMCC20628_RS11730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC20628_RS11735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMCC20628_RS11755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMCC20628_RS11755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMCC20628_RS11760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMCC20628_RS11765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMCC20628_RS11770	COG2989	Protein conserved in bacteria
IMCC20628_RS11785	COG0113	porphobilinogen synthase activity
IMCC20628_RS11795	COG3273	potassium ion transport
IMCC20628_RS11795	COG0471	metal ion transport
IMCC20628_RS11800	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IMCC20628_RS11815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC20628_RS11825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMCC20628_RS11830	COG0477	Major facilitator Superfamily
IMCC20628_RS11835	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IMCC20628_RS11840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IMCC20628_RS11845	COG1309	transcriptional regulator
IMCC20628_RS11870	COG5507	3-demethylubiquinone-9 3-methyltransferase
IMCC20628_RS11875	COG0248	Ppx GppA phosphatase
IMCC20628_RS11880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMCC20628_RS11890	COG0628	permease
IMCC20628_RS11895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC20628_RS11900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMCC20628_RS11905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMCC20628_RS11910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IMCC20628_RS11915	COG2132	Multicopper oxidase
IMCC20628_RS11930	COG1764	response to oxidative stress
IMCC20628_RS11935	COG1846	Transcriptional regulator
IMCC20628_RS11940	COG0243	molybdopterin cofactor binding
IMCC20628_RS11945	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IMCC20628_RS11970	COG1309	transcriptional regulator
IMCC20628_RS12010	COG0322	excinuclease ABC activity
IMCC20628_RS12015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC20628_RS12025	COG0314	molybdopterin synthase activity
IMCC20628_RS12030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMCC20628_RS12045	COG0105	UTP biosynthetic process
IMCC20628_RS12060	COG1063	alcohol dehydrogenase
IMCC20628_RS12065	COG0488	(ABC) transporter
IMCC20628_RS12075	COG0577	efflux transmembrane transporter activity
IMCC20628_RS12075	COG1136	(ABC) transporter
IMCC20628_RS12080	COG0577	efflux transmembrane transporter activity
IMCC20628_RS12080	COG1136	(ABC) transporter
IMCC20628_RS12085	COG2169	Transcriptional regulator
IMCC20628_RS12085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMCC20628_RS12105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC20628_RS12120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IMCC20628_RS12130	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IMCC20628_RS12135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMCC20628_RS12140	COG0194	GDP metabolic process
IMCC20628_RS12145	COG1561	YicC-like family, N-terminal region
IMCC20628_RS12150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMCC20628_RS12155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMCC20628_RS12160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC20628_RS12170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMCC20628_RS12175	COG0640	Transcriptional regulator
IMCC20628_RS12205	COG0667	Aldo Keto reductase
IMCC20628_RS12215	COG5001	Diguanylate cyclase
IMCC20628_RS12235	COG0360	Binds together with S18 to 16S ribosomal RNA
IMCC20628_RS12240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMCC20628_RS12250	COG0359	binds to the 23S rRNA
IMCC20628_RS12265	COG1573	uracil-dna glycosylase
IMCC20628_RS12270	COG2814	Major facilitator Superfamily
IMCC20628_RS12290	COG0308	aminopeptidase N
IMCC20628_RS12295	COG2202	Pas domain
IMCC20628_RS12295	COG2205	protein histidine kinase activity
IMCC20628_RS12330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IMCC20628_RS12335	COG2205	protein histidine kinase activity
IMCC20628_RS12340	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS12345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC20628_RS12355	COG3088	subunit of a heme lyase
IMCC20628_RS12360	COG1138	Cytochrome C-type biogenesis protein
IMCC20628_RS12365	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IMCC20628_RS12370	COG4235	cytochrome complex assembly
IMCC20628_RS12475	COG4695	Portal protein
IMCC20628_RS12510	COG2983	Belongs to the UPF0260 family
IMCC20628_RS12515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMCC20628_RS12550	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC20628_RS12575	COG2205	protein histidine kinase activity
IMCC20628_RS12585	COG2166	iron-sulfur cluster assembly
IMCC20628_RS12600	COG4957	zinc ion binding
IMCC20628_RS12605	COG1320	monovalent cation:proton antiporter activity
IMCC20628_RS12610	COG2212	antiporter activity
IMCC20628_RS12615	COG1863	multisubunit Na H antiporter MnhE subunit
IMCC20628_RS12620	COG0651	ATP synthesis coupled electron transport
IMCC20628_RS12625	COG1006	Multisubunit Na H antiporter MnhC subunit
IMCC20628_RS12630	COG2111	Na H antiporter
IMCC20628_RS12635	COG2111	Na H antiporter
IMCC20628_RS12635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMCC20628_RS12640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC20628_RS12645	COG0583	DNA-binding transcription factor activity
IMCC20628_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS12675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMCC20628_RS12680	COG1309	transcriptional regulator
IMCC20628_RS12695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IMCC20628_RS12715	COG0588	phosphoglycerate mutase activity
IMCC20628_RS12755	COG0583	DNA-binding transcription factor activity
IMCC20628_RS12760	COG1902	pentaerythritol trinitrate reductase activity
IMCC20628_RS12765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IMCC20628_RS12770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMCC20628_RS12775	COG1959	2 iron, 2 sulfur cluster binding
IMCC20628_RS12805	COG0656	L-ascorbic acid biosynthetic process
IMCC20628_RS12820	COG0440	acetolactate synthase activity
IMCC20628_RS12825	COG0028	Belongs to the TPP enzyme family
IMCC20628_RS12840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMCC20628_RS12845	COG0560	Phosphoserine phosphatase
IMCC20628_RS12860	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IMCC20628_RS12865	COG0330	HflC and HflK could
IMCC20628_RS12920	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IMCC20628_RS12935	COG0277	FAD linked oxidase domain protein
IMCC20628_RS12965	COG0210	DNA helicase
IMCC20628_RS12975	COG3012	SEC-C Motif Domain Protein
IMCC20628_RS12980	COG0598	Magnesium transport protein CorA
IMCC20628_RS12990	COG0412	Dienelactone hydrolase
IMCC20628_RS13000	COG5001	Diguanylate cyclase
IMCC20628_RS13000	COG3300	MHYT domain
IMCC20628_RS13060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMCC20628_RS13065	COG3909	cytochrome
IMCC20628_RS13070	COG2010	Cytochrome c
IMCC20628_RS13095	COG4977	sequence-specific DNA binding
IMCC20628_RS13095	COG1917	Cupin 2, conserved barrel domain protein
IMCC20628_RS13110	COG0697	spore germination
IMCC20628_RS13115	COG0076	glutamate decarboxylase activity
IMCC20628_RS13125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC20628_RS13145	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS13150	COG1309	transcriptional regulator
IMCC20628_RS13155	COG3119	arylsulfatase activity
IMCC20628_RS13160	COG0625	glutathione transferase activity
IMCC20628_RS13170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IMCC20628_RS13180	COG0175	sulfate reduction
IMCC20628_RS13185	COG0175	sulfate reduction
IMCC20628_RS13190	COG2895	sulfate adenylyltransferase (ATP) activity
IMCC20628_RS13210	COG0735	belongs to the Fur family
IMCC20628_RS13215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMCC20628_RS13220	COG1121	(ABC) transporter
IMCC20628_RS13230	COG2354	Protein conserved in bacteria
IMCC20628_RS13235	COG4221	oxidoreductase activity
IMCC20628_RS13235	COG3321	synthase
IMCC20628_RS13235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMCC20628_RS13235	COG0604	alcohol dehydrogenase
IMCC20628_RS13240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMCC20628_RS13260	COG0514	ATP-dependent DNA helicase (RecQ)
IMCC20628_RS13265	COG0251	oxidation-reduction process
IMCC20628_RS13285	COG3246	L-lysine catabolic process to acetate
IMCC20628_RS13290	COG3842	ATPase activity
IMCC20628_RS13300	COG1177	transmembrane transport
IMCC20628_RS13305	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS13310	COG0583	DNA-binding transcription factor activity
IMCC20628_RS13320	COG3383	formate dehydrogenase (NAD+) activity
IMCC20628_RS13360	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMCC20628_RS13375	COG1136	(ABC) transporter
IMCC20628_RS13405	COG0277	FAD linked oxidase domain protein
IMCC20628_RS13440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC20628_RS13460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC20628_RS13485	COG3620	sequence-specific DNA binding
IMCC20628_RS13500	COG4695	Portal protein
IMCC20628_RS13555	COG1802	Transcriptional regulator
IMCC20628_RS13555	COG4626	Terminase
IMCC20628_RS13635	COG2391	methyltransferase activity
IMCC20628_RS13640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC20628_RS13640	COG0574	Belongs to the PEP-utilizing enzyme family
IMCC20628_RS13660	COG1196	nuclear chromosome segregation
IMCC20628_RS13680	COG1194	a g-specific adenine glycosylase
IMCC20628_RS13695	COG0628	permease
IMCC20628_RS13705	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IMCC20628_RS13710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC20628_RS13725	COG0612	Peptidase, M16
IMCC20628_RS13740	COG1678	Uncharacterized ACR, COG1678
IMCC20628_RS13750	COG0678	peroxiredoxin activity
IMCC20628_RS13750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMCC20628_RS13755	COG0328	RNA-DNA hybrid ribonuclease activity
IMCC20628_RS13760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMCC20628_RS13765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMCC20628_RS13775	COG3346	SURF1 family
IMCC20628_RS13790	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IMCC20628_RS13795	COG0109	protoheme IX farnesyltransferase activity
IMCC20628_RS13800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC20628_RS13805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC20628_RS13815	COG0312	modulator of DNA gyrase
IMCC20628_RS13835	COG0259	pyridoxamine-phosphate oxidase activity
IMCC20628_RS13845	COG0484	heat shock protein binding
IMCC20628_RS13850	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC20628_RS13870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMCC20628_RS13875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC20628_RS13875	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC20628_RS13880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMCC20628_RS13885	COG3214	Protein conserved in bacteria
IMCC20628_RS13895	COG0123	including yeast histone deacetylase and acetoin utilization protein
IMCC20628_RS13900	COG1722	exodeoxyribonuclease VII activity
IMCC20628_RS13905	COG1741	Belongs to the pirin family
IMCC20628_RS13910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMCC20628_RS13925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMCC20628_RS13935	COG1024	Enoyl-CoA hydratase
IMCC20628_RS13940	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS13950	COG0009	L-threonylcarbamoyladenylate synthase
IMCC20628_RS13960	COG0277	FAD linked oxidase domain protein
IMCC20628_RS13970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IMCC20628_RS13975	COG0151	Belongs to the GarS family
IMCC20628_RS13985	COG0751	glycine-tRNA ligase activity
IMCC20628_RS14000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMCC20628_RS14005	COG1704	LemA family
IMCC20628_RS14025	COG0752	glycyl-tRNA synthetase alpha subunit
IMCC20628_RS14050	COG0142	geranyltranstransferase activity
IMCC20628_RS14060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMCC20628_RS14075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMCC20628_RS14080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC20628_RS14085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC20628_RS14090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC20628_RS14095	COG0356	it plays a direct role in the translocation of protons across the membrane
IMCC20628_RS14110	COG1160	GTP binding
IMCC20628_RS14135	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IMCC20628_RS14140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMCC20628_RS14145	COG0477	Major facilitator Superfamily
IMCC20628_RS14150	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS14165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMCC20628_RS14185	COG1566	PFAM secretion protein HlyD family protein
IMCC20628_RS14190	COG2814	Major facilitator Superfamily
IMCC20628_RS14195	COG3842	ATPase activity
IMCC20628_RS14200	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS14205	COG1175	transmembrane transport
IMCC20628_RS14220	COG0402	S-adenosylhomocysteine deaminase activity
IMCC20628_RS14225	COG2351	hydroxyisourate hydrolase activity
IMCC20628_RS14230	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IMCC20628_RS14235	COG3195	allantoin biosynthetic process
IMCC20628_RS14235	COG3648	Uricase
IMCC20628_RS14250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IMCC20628_RS14250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS14255	COG5002	protein histidine kinase activity
IMCC20628_RS14255	COG2205	protein histidine kinase activity
IMCC20628_RS14255	COG0784	Response regulator, receiver
IMCC20628_RS14260	COG5598	trimethylamine methyltransferase
IMCC20628_RS14270	COG2308	Evidence 4 Homologs of previously reported genes of
IMCC20628_RS14290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IMCC20628_RS14295	COG0830	nickel cation binding
IMCC20628_RS14305	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IMCC20628_RS14315	COG0804	urea catabolic process
IMCC20628_RS14320	COG3755	Protein conserved in bacteria
IMCC20628_RS14330	COG0832	Belongs to the urease beta subunit family
IMCC20628_RS14340	COG0831	urea catabolic process
IMCC20628_RS14345	COG0829	nickel cation binding
IMCC20628_RS14360	COG2081	HI0933 family
IMCC20628_RS14365	COG1086	Polysaccharide biosynthesis protein
IMCC20628_RS14380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC20628_RS14385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMCC20628_RS14390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC20628_RS14420	COG3842	ATPase activity
IMCC20628_RS14425	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS14430	COG1177	transmembrane transport
IMCC20628_RS14455	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IMCC20628_RS14460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC20628_RS14480	COG1802	Transcriptional regulator
IMCC20628_RS14490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMCC20628_RS14515	COG3665	Urea carboxylase-associated protein
IMCC20628_RS14520	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS14530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC20628_RS14535	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IMCC20628_RS14545	COG2986	histidine ammonia-lyase
IMCC20628_RS14550	COG1228	amidohydrolase
IMCC20628_RS14565	COG1024	Enoyl-CoA hydratase
IMCC20628_RS14575	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS14585	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC20628_RS14585	COG0824	Thioesterase
IMCC20628_RS14595	COG3246	L-lysine catabolic process to acetate
IMCC20628_RS14600	COG4977	sequence-specific DNA binding
IMCC20628_RS14610	COG4215	(ABC) transporter
IMCC20628_RS14615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC20628_RS14625	COG1834	amidinotransferase
IMCC20628_RS14630	COG1309	transcriptional regulator
IMCC20628_RS14650	COG0444	Belongs to the ABC transporter superfamily
IMCC20628_RS14655	COG4608	Belongs to the ABC transporter superfamily
IMCC20628_RS14660	COG0747	negative chemotaxis
IMCC20628_RS14665	COG0601	transmembrane transport
IMCC20628_RS14670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS14675	COG1305	Transglutaminase-like
IMCC20628_RS14690	COG0835	chemotaxis
IMCC20628_RS14695	COG0513	Belongs to the DEAD box helicase family
IMCC20628_RS14705	COG0583	DNA-binding transcription factor activity
IMCC20628_RS14715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMCC20628_RS14720	COG3842	ATPase activity
IMCC20628_RS14725	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS14730	COG1177	transmembrane transport
IMCC20628_RS14745	COG1129	ABC transporter
IMCC20628_RS14750	COG4214	carbohydrate transport
IMCC20628_RS14755	COG1879	ABC-type sugar transport system periplasmic component
IMCC20628_RS14780	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS14790	COG1414	Transcriptional regulator
IMCC20628_RS14800	COG1175	transmembrane transport
IMCC20628_RS14805	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS14820	COG3734	2-keto-3-deoxy-galactonokinase
IMCC20628_RS14825	COG0800	Aldolase
IMCC20628_RS14830	COG3386	PFAM SMP-30 Gluconolaconase
IMCC20628_RS14840	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC20628_RS14840	COG1902	pentaerythritol trinitrate reductase activity
IMCC20628_RS14850	COG5598	trimethylamine methyltransferase
IMCC20628_RS14860	COG3300	MHYT domain
IMCC20628_RS14860	COG5001	Diguanylate cyclase
IMCC20628_RS14865	COG5002	protein histidine kinase activity
IMCC20628_RS14865	COG2205	protein histidine kinase activity
IMCC20628_RS14865	COG0784	Response regulator, receiver
IMCC20628_RS14870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMCC20628_RS14880	COG1663	tetraacyldisaccharide 4'-kinase activity
IMCC20628_RS14885	COG1519	Transferase
IMCC20628_RS14900	COG1218	3'(2'),5'-bisphosphate nucleotidase
IMCC20628_RS14905	COG0312	modulator of DNA gyrase
IMCC20628_RS14930	COG0742	ribosomal rna small subunit methyltransferase
IMCC20628_RS14935	COG1187	pseudouridine synthase activity
IMCC20628_RS14940	COG0590	tRNA wobble adenosine to inosine editing
IMCC20628_RS14955	COG4221	oxidoreductase activity
IMCC20628_RS14965	COG0196	riboflavin kinase activity
IMCC20628_RS14975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMCC20628_RS14980	COG0459	protein refolding
IMCC20628_RS14990	COG2259	Doxx family
IMCC20628_RS15000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMCC20628_RS15005	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMCC20628_RS15010	COG0124	histidyl-tRNA synthetase
IMCC20628_RS15030	COG2818	Glycosylase
IMCC20628_RS15035	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS15040	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS15045	COG0247	lactate metabolic process
IMCC20628_RS15065	COG0277	FAD linked oxidase domain protein
IMCC20628_RS15070	COG0277	FAD linked oxidase domain protein
IMCC20628_RS15075	COG2186	Transcriptional regulator
IMCC20628_RS15080	COG0247	lactate metabolic process
IMCC20628_RS15085	COG1139	Iron-sulfur cluster binding protein
IMCC20628_RS15095	COG2258	MOSC domain
IMCC20628_RS15100	COG1280	lysine exporter protein (LysE YggA)
IMCC20628_RS15115	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IMCC20628_RS15130	COG0583	DNA-binding transcription factor activity
IMCC20628_RS15155	COG0477	Major facilitator Superfamily
IMCC20628_RS15160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IMCC20628_RS15195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC20628_RS15205	COG1074	ATP-dependent DNA helicase activity
IMCC20628_RS15220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC20628_RS15245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IMCC20628_RS15275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS15295	COG3415	Transposase
IMCC20628_RS15295	COG2801	Transposase and inactivated derivatives
IMCC20628_RS15305	COG3550	peptidyl-serine autophosphorylation
IMCC20628_RS15315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC20628_RS15325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC20628_RS15350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS15360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS15395	COG2205	protein histidine kinase activity
IMCC20628_RS15400	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS15425	COG0746	molybdenum cofactor guanylyltransferase activity
IMCC20628_RS15435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMCC20628_RS15435	COG3608	succinylglutamate desuccinylase aspartoacylase
IMCC20628_RS15445	COG0542	response to heat
IMCC20628_RS15480	COG1177	transmembrane transport
IMCC20628_RS15485	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS15490	COG3842	ATPase activity
IMCC20628_RS15495	COG2197	response regulator
IMCC20628_RS15510	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IMCC20628_RS15520	COG3448	diguanylate cyclase activity
IMCC20628_RS15520	COG4175	Glycine betaine
IMCC20628_RS15525	COG4176	ABC-type proline glycine betaine transport system permease component
IMCC20628_RS15540	COG2084	Dehydrogenase
IMCC20628_RS15545	COG1129	ABC transporter
IMCC20628_RS15550	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS15555	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS15565	COG1879	ABC-type sugar transport system periplasmic component
IMCC20628_RS15570	COG1653	transport
IMCC20628_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS15585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMCC20628_RS15590	COG0022	dehydrogenase e1 component
IMCC20628_RS15595	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC20628_RS15605	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC20628_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS15615	COG1846	Transcriptional regulator
IMCC20628_RS15635	COG1879	ABC-type sugar transport system periplasmic component
IMCC20628_RS15645	COG1070	Carbohydrate kinase
IMCC20628_RS15650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC20628_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS15665	COG4172	Belongs to the ABC transporter superfamily
IMCC20628_RS15670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS15680	COG0747	negative chemotaxis
IMCC20628_RS15700	COG1522	sequence-specific DNA binding
IMCC20628_RS15720	COG5564	TIM-barrel signal transduction protein
IMCC20628_RS15740	COG1175	transmembrane transport
IMCC20628_RS15745	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS15755	COG3842	ATPase activity
IMCC20628_RS15760	COG3842	ATPase activity
IMCC20628_RS15765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMCC20628_RS15775	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC20628_RS15780	COG1082	Xylose isomerase domain protein TIM barrel
IMCC20628_RS15785	COG1082	Xylose isomerase domain protein TIM barrel
IMCC20628_RS15795	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS15800	COG3618	amidohydrolase
IMCC20628_RS15810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMCC20628_RS15820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMCC20628_RS15840	COG1917	Cupin 2, conserved barrel domain protein
IMCC20628_RS15840	COG2169	Transcriptional regulator
IMCC20628_RS15845	COG1368	sulfuric ester hydrolase activity
IMCC20628_RS15880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMCC20628_RS15900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS15910	COG2186	Transcriptional regulator
IMCC20628_RS15920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC20628_RS15930	COG1802	Transcriptional regulator
IMCC20628_RS15945	COG3485	protocatechuate 3,4-dioxygenase
IMCC20628_RS15970	COG0778	Nitroreductase
IMCC20628_RS15995	COG2358	TRAP transporter, solute receptor (TAXI family
IMCC20628_RS16005	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC20628_RS16010	COG0625	glutathione transferase activity
IMCC20628_RS16015	COG2814	Major facilitator Superfamily
IMCC20628_RS16020	COG3842	ATPase activity
IMCC20628_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS16050	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IMCC20628_RS16055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMCC20628_RS16110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC20628_RS16115	COG0579	oxidoreductase
IMCC20628_RS16160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC20628_RS16165	COG3608	succinylglutamate desuccinylase aspartoacylase
IMCC20628_RS16170	COG0006	proline dipeptidase activity
IMCC20628_RS16175	COG2423	ornithine cyclodeaminase activity
IMCC20628_RS16180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMCC20628_RS16190	COG0765	amino acid transport
IMCC20628_RS16195	COG0765	amino acid transport
IMCC20628_RS16205	COG1126	abc transporter atp-binding protein
IMCC20628_RS16210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC20628_RS16215	COG1522	sequence-specific DNA binding
IMCC20628_RS16220	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS16225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC20628_RS16230	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS16245	COG3718	enzyme involved in inositol metabolism
IMCC20628_RS16255	COG0425	Belongs to the sulfur carrier protein TusA family
IMCC20628_RS16260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMCC20628_RS16265	COG0746	molybdenum cofactor guanylyltransferase activity
IMCC20628_RS16275	COG0303	'Molybdopterin
IMCC20628_RS16295	COG0489	protein tyrosine kinase activity
IMCC20628_RS16345	COG0437	4 iron, 4 sulfur cluster binding
IMCC20628_RS16350	COG0243	molybdopterin cofactor binding
IMCC20628_RS16350	COG3383	formate dehydrogenase (NAD+) activity
IMCC20628_RS16365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS16375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS16395	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS16400	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS16405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC20628_RS16410	COG0235	Class ii aldolase
IMCC20628_RS16420	COG1942	4-Oxalocrotonate Tautomerase
IMCC20628_RS16425	COG2721	sulfolactate sulfo-lyase activity
IMCC20628_RS16440	COG2204	response regulator
IMCC20628_RS16480	COG0454	-acetyltransferase
IMCC20628_RS16480	COG0456	acetyltransferase
IMCC20628_RS16515	COG1671	Belongs to the UPF0178 family
IMCC20628_RS16540	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC20628_RS16550	COG1215	transferase activity, transferring glycosyl groups
IMCC20628_RS16605	COG0683	leucine binding
IMCC20628_RS16640	COG1121	(ABC) transporter
IMCC20628_RS16645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMCC20628_RS16650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMCC20628_RS16655	COG0662	Cupin 2, conserved barrel domain protein
IMCC20628_RS16660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC20628_RS16665	COG0509	glycine decarboxylation via glycine cleavage system
IMCC20628_RS16670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC20628_RS16670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC20628_RS16730	COG2205	protein histidine kinase activity
IMCC20628_RS16750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC20628_RS16765	COG1177	transmembrane transport
IMCC20628_RS16770	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC20628_RS16780	COG3842	ATPase activity
IMCC20628_RS16795	COG2224	Isocitrate lyase
IMCC20628_RS16805	COG2814	Major facilitator Superfamily
IMCC20628_RS16815	COG2801	Transposase and inactivated derivatives
IMCC20628_RS16815	COG3415	Transposase
IMCC20628_RS16830	COG2972	Histidine kinase
IMCC20628_RS16830	COG0840	transmembrane signaling receptor activity
IMCC20628_RS16840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC20628_RS16855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMCC20628_RS16860	COG0363	glucosamine-6-phosphate deaminase activity
IMCC20628_RS16865	COG0129	dihydroxy-acid dehydratase activity
IMCC20628_RS16900	COG3842	ATPase activity
IMCC20628_RS16905	COG0366	Alpha amylase catalytic
IMCC20628_RS16910	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS16915	COG1175	transmembrane transport
IMCC20628_RS16920	COG1653	transport
IMCC20628_RS16925	COG1609	Transcriptional regulator
IMCC20628_RS16945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMCC20628_RS17000	COG1684	flagellar biosynthetic protein fliR
IMCC20628_RS17005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMCC20628_RS17010	COG4794	Type iii secretion
IMCC20628_RS17020	COG5443	negative regulation of bacterial-type flagellum assembly
IMCC20628_RS17035	COG4786	Flagellar basal body rod
IMCC20628_RS17035	COG1256	bacterial-type flagellum assembly
IMCC20628_RS17040	COG1749	Flagellar hook protein flgE
IMCC20628_RS17065	COG1360	Flagellar Motor Protein
IMCC20628_RS17075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC20628_RS17080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC20628_RS17085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC20628_RS17090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC20628_RS17095	COG1338	Plays a role in the flagellum-specific transport system
IMCC20628_RS17105	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IMCC20628_RS17115	COG1706	bacterial-type flagellum-dependent cell motility
IMCC20628_RS17120	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IMCC20628_RS17125	COG4786	Flagellar basal body rod
IMCC20628_RS17130	COG1677	Flagellar hook-basal body complex protein FliE
IMCC20628_RS17135	COG1558	bacterial-type flagellum-dependent cell motility
IMCC20628_RS17140	COG1815	bacterial-type flagellum-dependent cell motility
IMCC20628_RS17150	COG1157	protein secretion by the type III secretion system
IMCC20628_RS17155	COG4786	Flagellar basal body rod
IMCC20628_RS17170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IMCC20628_RS17175	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMCC20628_RS17180	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMCC20628_RS17185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMCC20628_RS17190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMCC20628_RS17200	COG2197	response regulator
IMCC20628_RS17205	COG2771	luxR family
IMCC20628_RS17210	COG1766	The M ring may be actively involved in energy transduction
IMCC20628_RS17220	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IMCC20628_RS17225	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS17230	COG2201	protein-glutamate methylesterase activity
IMCC20628_RS17235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IMCC20628_RS17240	COG2198	Histidine kinase
IMCC20628_RS17240	COG0643	Histidine kinase
IMCC20628_RS17245	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS17255	COG0840	transmembrane signaling receptor activity
IMCC20628_RS17270	COG0641	radical SAM
IMCC20628_RS17315	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IMCC20628_RS17325	COG1294	oxidase, subunit
IMCC20628_RS17335	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS17345	COG0411	ABC transporter
IMCC20628_RS17350	COG0410	ABC transporter
IMCC20628_RS17360	COG3243	poly(R)-hydroxyalkanoic acid synthase
IMCC20628_RS17365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMCC20628_RS17390	COG0411	ABC transporter
IMCC20628_RS17405	COG1846	Transcriptional regulator
IMCC20628_RS17440	COG1335	isochorismatase
IMCC20628_RS17445	COG2309	aminopeptidase activity
IMCC20628_RS17450	COG0596	Alpha beta hydrolase
IMCC20628_RS17455	COG3473	Maleate cis-trans isomerase
IMCC20628_RS17465	COG3415	Transposase
IMCC20628_RS17465	COG2801	Transposase and inactivated derivatives
IMCC20628_RS17480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC20628_RS17485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC20628_RS17490	COG1845	cytochrome c oxidase, subunit III
IMCC20628_RS17500	COG2095	MarC family integral membrane protein
IMCC20628_RS17505	COG4993	Dehydrogenase
IMCC20628_RS17515	COG2963	transposase activity
IMCC20628_RS17525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMCC20628_RS17580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IMCC20628_RS17585	COG0424	maF-like protein
IMCC20628_RS17590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMCC20628_RS17600	COG5328	Belongs to the UPF0262 family
IMCC20628_RS17605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMCC20628_RS17615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMCC20628_RS17635	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IMCC20628_RS17640	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IMCC20628_RS17660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMCC20628_RS17665	COG0328	RNA-DNA hybrid ribonuclease activity
IMCC20628_RS17720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC20628_RS17745	COG5001	Diguanylate cyclase
IMCC20628_RS17745	COG3300	MHYT domain
IMCC20628_RS17760	COG2801	Transposase and inactivated derivatives
IMCC20628_RS17760	COG3415	Transposase
IMCC20628_RS17775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMCC20628_RS17785	COG1024	Enoyl-CoA hydratase
IMCC20628_RS17795	COG0436	Aminotransferase
IMCC20628_RS17800	COG1970	mechanosensitive ion channel activity
IMCC20628_RS17805	COG2205	protein histidine kinase activity
IMCC20628_RS17805	COG0784	Response regulator, receiver
IMCC20628_RS17805	COG2198	Histidine kinase
IMCC20628_RS17825	COG0167	dihydroorotate dehydrogenase activity
IMCC20628_RS17830	COG0534	Mate efflux family protein
IMCC20628_RS17840	COG0123	including yeast histone deacetylase and acetoin utilization protein
IMCC20628_RS17850	COG1793	dna ligase
IMCC20628_RS17865	COG1201	RNA secondary structure unwinding
IMCC20628_RS17880	COG0730	response to heat
IMCC20628_RS17895	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS17900	COG1960	acyl-CoA dehydrogenase activity
IMCC20628_RS17910	COG0183	Belongs to the thiolase family
IMCC20628_RS17915	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC20628_RS17915	COG1024	Enoyl-CoA hydratase
IMCC20628_RS17965	COG0717	Belongs to the dCTP deaminase family
IMCC20628_RS17975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC20628_RS17980	COG2967	ApaG domain
IMCC20628_RS17985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMCC20628_RS18005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMCC20628_RS18010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMCC20628_RS18025	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS18030	COG0704	Plays a role in the regulation of phosphate uptake
IMCC20628_RS18035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC20628_RS18045	COG0573	inorganic phosphate transmembrane transporter activity
IMCC20628_RS18055	COG5002	protein histidine kinase activity
IMCC20628_RS18060	COG0114	fumarate hydratase activity
IMCC20628_RS18065	COG2326	polyphosphate kinase activity
IMCC20628_RS18070	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS18075	COG0166	Belongs to the GPI family
IMCC20628_RS18085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMCC20628_RS18090	COG0418	dihydroorotase activity
IMCC20628_RS18095	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS18105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMCC20628_RS18115	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IMCC20628_RS18125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC20628_RS18130	COG0433	COG0433 Predicted ATPase
IMCC20628_RS18140	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS18145	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IMCC20628_RS18160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC20628_RS18170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC20628_RS18190	COG0006	proline dipeptidase activity
IMCC20628_RS18195	COG1522	sequence-specific DNA binding
IMCC20628_RS18220	COG1215	transferase activity, transferring glycosyl groups
IMCC20628_RS18225	COG3250	beta-galactosidase activity
IMCC20628_RS18225	COG5297	Belongs to the glycosyl hydrolase family 6
IMCC20628_RS18245	COG0450	alkyl hydroperoxide reductase
IMCC20628_RS18270	COG2326	polyphosphate kinase activity
IMCC20628_RS18275	COG3135	benzoate transporter
IMCC20628_RS18280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMCC20628_RS18285	COG3800	Transcriptional regulator
IMCC20628_RS18285	COG1396	sequence-specific DNA binding
IMCC20628_RS18290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC20628_RS18295	COG0625	glutathione transferase activity
IMCC20628_RS18305	COG4770	biotin carboxylase activity
IMCC20628_RS18310	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC20628_RS18310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC20628_RS18315	COG2852	Protein conserved in bacteria
IMCC20628_RS18325	COG4608	Belongs to the ABC transporter superfamily
IMCC20628_RS18330	COG0444	Belongs to the ABC transporter superfamily
IMCC20628_RS18335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS18340	COG0601	transmembrane transport
IMCC20628_RS18345	COG0747	negative chemotaxis
IMCC20628_RS18355	COG0587	DNA-directed DNA polymerase activity
IMCC20628_RS18380	COG2721	sulfolactate sulfo-lyase activity
IMCC20628_RS18390	COG4154	Belongs to the RbsD FucU family
IMCC20628_RS18405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC20628_RS18410	COG0275	rRNA processing
IMCC20628_RS18425	COG0275	rRNA processing
IMCC20628_RS18435	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS18470	COG5002	protein histidine kinase activity
IMCC20628_RS18480	COG0398	Pfam SNARE associated Golgi protein
IMCC20628_RS18490	COG0594	ribonuclease P activity
IMCC20628_RS18495	COG0706	membrane insertase activity
IMCC20628_RS18500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IMCC20628_RS18505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC20628_RS18510	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IMCC20628_RS18525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC20628_RS18560	COG2171	N-acyltransferase activity
IMCC20628_RS18570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC20628_RS18580	COG0840	transmembrane signaling receptor activity
IMCC20628_RS18590	COG0101	tRNA pseudouridine synthase activity
IMCC20628_RS18595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMCC20628_RS18600	COG0242	peptide deformylase activity
IMCC20628_RS18615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC20628_RS18620	COG1957	nucleoside hydrolase
IMCC20628_RS18625	COG0071	Belongs to the small heat shock protein (HSP20) family
IMCC20628_RS18635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMCC20628_RS18640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMCC20628_RS18645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IMCC20628_RS18650	COG1137	ATPase activity
IMCC20628_RS18655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IMCC20628_RS18665	COG0616	signal peptide processing
IMCC20628_RS18670	COG0776	regulation of translation
IMCC20628_RS18690	COG0789	Transcriptional regulator
IMCC20628_RS18700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IMCC20628_RS18710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMCC20628_RS18715	COG0604	alcohol dehydrogenase
IMCC20628_RS18720	COG5002	protein histidine kinase activity
IMCC20628_RS18720	COG2205	protein histidine kinase activity
IMCC20628_RS18720	COG0784	Response regulator, receiver
IMCC20628_RS18730	COG0281	malic enzyme
IMCC20628_RS18730	COG0280	phosphate acetyltransferase
IMCC20628_RS18735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMCC20628_RS18745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC20628_RS18750	COG2860	membrane
IMCC20628_RS18755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMCC20628_RS18760	COG1420	regulation of RNA biosynthetic process
IMCC20628_RS18765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMCC20628_RS18770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMCC20628_RS18775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMCC20628_RS18780	COG3300	MHYT domain
IMCC20628_RS18780	COG5001	Diguanylate cyclase
IMCC20628_RS18790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMCC20628_RS18795	COG0792	nuclease activity
IMCC20628_RS18810	COG3842	ATPase activity
IMCC20628_RS18815	COG3842	ATPase activity
IMCC20628_RS18825	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS18840	COG0189	ligase activity
IMCC20628_RS18860	COG3938	Belongs to the proline racemase family
IMCC20628_RS18865	COG0756	dUTP diphosphatase activity
IMCC20628_RS18870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMCC20628_RS18900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC20628_RS18905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC20628_RS18920	COG4529	Protein conserved in bacteria
IMCC20628_RS18925	COG0784	Response regulator, receiver
IMCC20628_RS18945	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC20628_RS18955	COG1609	Transcriptional regulator
IMCC20628_RS19010	COG1063	alcohol dehydrogenase
IMCC20628_RS19030	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IMCC20628_RS19080	COG1741	Belongs to the pirin family
IMCC20628_RS19090	COG1522	sequence-specific DNA binding
IMCC20628_RS19110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMCC20628_RS19115	COG1047	Peptidyl-prolyl cis-trans
IMCC20628_RS19125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IMCC20628_RS19130	COG2226	methyltransferase
IMCC20628_RS19135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMCC20628_RS19140	COG1024	Enoyl-CoA hydratase
IMCC20628_RS19145	COG0268	Binds directly to 16S ribosomal RNA
IMCC20628_RS19150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMCC20628_RS19160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC20628_RS19195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMCC20628_RS19205	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC20628_RS19220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IMCC20628_RS19220	COG3008	intermembrane lipid transfer
IMCC20628_RS19225	COG2995	paraquat-inducible protein a
IMCC20628_RS19235	COG1295	ribonuclease BN
IMCC20628_RS19240	COG1185	polyribonucleotide nucleotidyltransferase activity
IMCC20628_RS19245	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMCC20628_RS19255	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IMCC20628_RS19260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMCC20628_RS19270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMCC20628_RS19275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC20628_RS19285	COG0195	Participates in both transcription termination and antitermination
IMCC20628_RS19285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC20628_RS19290	COG0779	Required for maturation of 30S ribosomal subunits
IMCC20628_RS19295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMCC20628_RS19300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMCC20628_RS19305	COG1396	sequence-specific DNA binding
IMCC20628_RS19310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IMCC20628_RS19315	COG4535	Mg2 and Co2 transporter CorC
IMCC20628_RS19320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMCC20628_RS19325	COG1702	phosphate starvation-inducible protein PhoH
IMCC20628_RS19330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC20628_RS19350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC20628_RS19355	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IMCC20628_RS19365	COG0180	Tryptophanyl-tRNA synthetase
IMCC20628_RS19370	COG0728	peptidoglycan biosynthetic process
IMCC20628_RS19375	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IMCC20628_RS19380	COG0189	ligase activity
IMCC20628_RS19385	COG0456	acetyltransferase
IMCC20628_RS19385	COG1214	PFAM Peptidase M22, glycoprotease
IMCC20628_RS19420	COG2169	Transcriptional regulator
IMCC20628_RS19420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMCC20628_RS19425	COG0588	phosphoglycerate mutase activity
IMCC20628_RS19430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMCC20628_RS19435	COG1132	(ABC) transporter
IMCC20628_RS19440	COG0837	glucose binding
IMCC20628_RS19445	COG1803	Methylglyoxal synthase
IMCC20628_RS19480	COG0072	phenylalanine-tRNA ligase activity
IMCC20628_RS19480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC20628_RS19485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMCC20628_RS19490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMCC20628_RS19500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMCC20628_RS19570	COG0582	viral genome integration into host DNA
IMCC20628_RS19585	COG0481	GTPase activity
IMCC20628_RS19595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMCC20628_RS19605	COG2801	Transposase and inactivated derivatives
IMCC20628_RS19605	COG3415	Transposase
IMCC20628_RS19615	COG3415	Transposase
IMCC20628_RS19615	COG2801	Transposase and inactivated derivatives
IMCC20628_RS19635	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS19640	COG1175	transmembrane transport
IMCC20628_RS19660	COG1070	Carbohydrate kinase
IMCC20628_RS19665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMCC20628_RS19670	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMCC20628_RS19675	COG2188	Transcriptional regulator
IMCC20628_RS19690	COG2801	Transposase and inactivated derivatives
IMCC20628_RS19690	COG3415	Transposase
IMCC20628_RS19750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS19755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS19775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS19780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS19785	COG1116	anion transmembrane transporter activity
IMCC20628_RS19825	COG1744	ABC transporter substrate-binding protein PnrA-like
IMCC20628_RS19840	COG0539	negative regulation of cytoplasmic translation
IMCC20628_RS19845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMCC20628_RS19880	COG3227	Zinc metalloprotease (Elastase)
IMCC20628_RS19890	COG2010	Cytochrome c
IMCC20628_RS19925	COG0662	Cupin 2, conserved barrel domain protein
IMCC20628_RS19925	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IMCC20628_RS19930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC20628_RS19950	COG2186	Transcriptional regulator
IMCC20628_RS19975	COG1082	Xylose isomerase domain protein TIM barrel
IMCC20628_RS19985	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMCC20628_RS20010	COG2186	Transcriptional regulator
IMCC20628_RS20015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC20628_RS20040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC20628_RS20045	COG2951	lytic endotransglycosylase activity
IMCC20628_RS20055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMCC20628_RS20060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMCC20628_RS20065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMCC20628_RS20075	COG2816	NAD+ diphosphatase activity
IMCC20628_RS20080	COG0077	Prephenate dehydratase
IMCC20628_RS20080	COG1605	Chorismate mutase
IMCC20628_RS20085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IMCC20628_RS20090	COG3474	cytochrome
IMCC20628_RS20095	COG4166	transmembrane transport
IMCC20628_RS20100	COG4174	ABC transporter (Permease)
IMCC20628_RS20105	COG4239	(ABC) transporter, permease
IMCC20628_RS20110	COG4172	Belongs to the ABC transporter superfamily
IMCC20628_RS20115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC20628_RS20130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC20628_RS20165	COG4964	Belongs to the GSP D family
IMCC20628_RS20210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMCC20628_RS20215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IMCC20628_RS20220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMCC20628_RS20230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IMCC20628_RS20235	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS20240	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMCC20628_RS20255	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS20260	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC20628_RS20265	COG3845	ABC transporter
IMCC20628_RS20275	COG2900	Belongs to the SlyX family
IMCC20628_RS20280	COG0823	Involved in the tonB-independent uptake of proteins
IMCC20628_RS20285	COG3507	Belongs to the glycosyl hydrolase 43 family
IMCC20628_RS20290	COG0667	Aldo Keto reductase
IMCC20628_RS20305	COG3842	ATPase activity
IMCC20628_RS20310	COG0395	ABC-type sugar transport system, permease component
IMCC20628_RS20315	COG1175	transmembrane transport
IMCC20628_RS20320	COG1653	transport
IMCC20628_RS20325	COG1609	Transcriptional regulator
IMCC20628_RS20330	COG0640	Transcriptional regulator
IMCC20628_RS20335	COG0243	molybdopterin cofactor binding
IMCC20628_RS20340	COG0437	4 iron, 4 sulfur cluster binding
IMCC20628_RS20345	COG3302	dmso reductase anchor subunit
IMCC20628_RS20350	COG2358	TRAP transporter, solute receptor (TAXI family
IMCC20628_RS20365	COG1570	exodeoxyribonuclease VII activity
IMCC20628_RS20375	COG1573	uracil-dna glycosylase
IMCC20628_RS20385	COG1393	Belongs to the ArsC family
IMCC20628_RS20390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC20628_RS20390	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC20628_RS20405	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IMCC20628_RS20410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMCC20628_RS20410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC20628_RS20420	COG1012	belongs to the aldehyde dehydrogenase family
IMCC20628_RS20430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC20628_RS20440	COG0747	negative chemotaxis
IMCC20628_RS20445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC20628_RS20450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMCC20628_RS20460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMCC20628_RS20470	COG1968	undecaprenyl-diphosphatase activity
IMCC20628_RS20480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC20628_RS20490	COG0284	orotidine-5'-phosphate decarboxylase activity
IMCC20628_RS20500	COG3963	phosphatidate phosphatase activity
IMCC20628_RS20505	COG0484	heat shock protein binding
IMCC20628_RS20510	COG0443	Heat shock 70 kDa protein
IMCC20628_RS20515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMCC20628_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC20628_RS20535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC20628_RS20535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC20628_RS20540	COG4134	Bacterial extracellular solute-binding protein
IMCC20628_RS20550	COG4136	ATPase activity
IMCC20628_RS20555	COG1643	Atp-dependent helicase
IMCC20628_RS20565	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IMCC20628_RS20575	COG1376	ErfK ybiS ycfS ynhG family protein
IMCC20628_RS20580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IMCC20628_RS20600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC20628_RS20605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC20628_RS20610	COG0028	Belongs to the TPP enzyme family
IMCC20628_RS20615	COG0861	Integral membrane protein TerC family
IMCC20628_RS20645	COG0135	phosphoribosylanthranilate isomerase activity
IMCC20628_RS20650	COG0133	tryptophan synthase activity
IMCC20628_RS20655	COG0159	tryptophan synthase activity
IMCC20628_RS20660	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMCC20628_RS20665	COG0285	dihydrofolate synthase activity
IMCC20628_RS20685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC20628_RS20690	COG3178	'Phosphotransferase
IMCC20628_RS20695	COG2205	protein histidine kinase activity
IMCC20628_RS20700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMCC20628_RS20705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMCC20628_RS20710	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMCC20628_RS20710	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMCC20628_RS20720	COG2205	protein histidine kinase activity
IMCC20628_RS20725	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS20730	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMCC20628_RS20735	COG0778	Nitroreductase
IMCC20628_RS20735	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IMCC20628_RS20745	COG1652	LysM domain
IMCC20628_RS20760	COG1072	(Pantothenic acid kinase))
IMCC20628_RS20765	COG0140	phosphoribosyl-ATP diphosphatase activity
IMCC20628_RS20770	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC20628_RS20775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMCC20628_RS20780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMCC20628_RS20790	COG0131	Imidazoleglycerol-phosphate dehydratase
IMCC20628_RS20795	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IMCC20628_RS20805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMCC20628_RS20820	COG2840	Smr protein MutS2
IMCC20628_RS20825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IMCC20628_RS20840	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IMCC20628_RS20850	COG0237	dephospho-CoA kinase activity
IMCC20628_RS20855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC20628_RS20860	COG0424	maF-like protein
IMCC20628_RS20865	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IMCC20628_RS20870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IMCC20628_RS20875	COG1981	membrane
IMCC20628_RS20880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMCC20628_RS20885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMCC20628_RS20890	COG0445	tRNA wobble uridine modification
IMCC20628_RS20895	COG0357	Ribosomal RNA small subunit methyltransferase G
IMCC20628_RS20920	COG0495	leucyl-tRNA aminoacylation
IMCC20628_RS20925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMCC20628_RS20945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC20628_RS20960	COG0501	Belongs to the peptidase M48B family
IMCC20628_RS20975	COG0138	bifunctional purine biosynthesis protein purh
IMCC20628_RS20985	COG2902	Dehydrogenase
IMCC20628_RS21000	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IMCC20628_RS21005	COG0288	reversible hydration of carbon dioxide
IMCC20628_RS21020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMCC20628_RS21035	COG0384	phenazine biosynthesis protein PhzF
IMCC20628_RS21040	COG1522	sequence-specific DNA binding
IMCC20628_RS21045	COG0473	3-isopropylmalate dehydrogenase activity
IMCC20628_RS21065	COG0066	3-isopropylmalate dehydratase activity
IMCC20628_RS21075	COG2301	Belongs to the HpcH HpaI aldolase family
IMCC20628_RS21085	COG1473	amidohydrolase
IMCC20628_RS21120	COG2835	tetraacyldisaccharide 4'-kinase activity
IMCC20628_RS21125	COG1309	transcriptional regulator
IMCC20628_RS21130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMCC20628_RS21135	COG1946	Acyl-CoA thioesterase
IMCC20628_RS21140	COG0347	Belongs to the P(II) protein family
IMCC20628_RS21145	COG0004	ammonium transporteR
IMCC20628_RS21150	COG0347	Belongs to the P(II) protein family
IMCC20628_RS21155	COG0004	ammonium transporteR
IMCC20628_RS21160	COG1674	ftsk spoiiie
IMCC20628_RS21165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IMCC20628_RS21175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC20628_RS21180	COG0745	RESPONSE REGULATOR receiver
IMCC20628_RS21215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC20628_RS21220	COG0181	hydroxymethylbilane synthase activity
IMCC20628_RS21255	COG1872	DUF167
IMCC20628_RS21260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IMCC20628_RS21265	COG1247	-acetyltransferase
IMCC20628_RS21275	COG1217	gtp-binding protein TYPA
IMCC20628_RS21280	COG0339	signal peptide processing
IMCC20628_RS21285	COG0137	argininosuccinate synthase activity
IMCC20628_RS21305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMCC20628_RS21325	COG1595	DNA-templated transcription, initiation
IMCC20628_RS21335	COG2154	pterin-4-alpha-carbinolamine dehydratase
IMCC20628_RS21340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMCC20628_RS21345	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMCC20628_RS21355	COG4181	ATPase activity
IMCC20628_RS21365	COG0670	Belongs to the BI1 family
IMCC20628_RS21385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMCC20628_RS21390	COG4133	protoheme IX ABC transporter activity
IMCC20628_RS21395	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC20628_RS21400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC20628_RS21410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC20628_RS21425	COG0640	Transcriptional regulator
IMCC20628_RS21440	COG2917	probably involved in intracellular septation
IMCC20628_RS21445	COG0552	protein localization to endoplasmic reticulum
IMCC20628_RS21450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC20628_RS21455	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMCC20628_RS21480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC20628_RS21495	COG3273	potassium ion transport
IMCC20628_RS21495	COG0471	metal ion transport
IMCC20628_RS21500	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMCC20628_RS21505	COG3668	Plasmid stabilization system
IMCC20628_RS21510	COG1272	protein, Hemolysin III
IMCC20628_RS21515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMCC20628_RS21525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMCC20628_RS21535	COG0228	four-way junction DNA binding
IMCC20628_RS21540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMCC20628_RS21545	COG0336	Belongs to the RNA methyltransferase TrmD family
IMCC20628_RS21555	COG0335	large ribosomal subunit rRNA binding
IMCC20628_RS21570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC20628_RS21580	COG0765	amino acid transport
IMCC20628_RS21590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMCC20628_RS21630	COG4452	Inner membrane protein CreD
IMCC20628_RS21635	COG0626	cystathionine gamma-synthase activity
IMCC20628_RS21665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC20628_RS21670	COG2845	Protein of unknown function (DUF459)
IMCC20628_RS21675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IMCC20628_RS21680	COG0039	L-malate dehydrogenase activity
IMCC20628_RS21685	COG0045	succinate-CoA ligase (ADP-forming) activity
IMCC20628_RS21690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMCC20628_RS21705	COG0567	Dehydrogenase, E1 component
IMCC20628_RS21710	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC20628_RS21745	COG4974	Belongs to the 'phage' integrase family
IMCC20628_RS21755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMCC20628_RS21810	COG0697	spore germination
IMCC20628_RS21820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC20628_RS21825	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMCC20628_RS21830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC20628_RS21835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC20628_RS21840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMCC20628_RS21855	COG0494	nUDIX hydrolase
IMCC20628_RS21865	COG0793	Belongs to the peptidase S41A family
IMCC20628_RS21870	COG4942	peptidase
IMCC20628_RS21875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMCC20628_RS21880	COG0799	negative regulation of ribosome biogenesis
IMCC20628_RS21885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMCC20628_RS21890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC20628_RS21895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC20628_RS21900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMCC20628_RS21915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMCC20628_RS21920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC20628_RS21920	COG3743	rRNA binding
IMCC20628_RS21985	COG3622	Belongs to the hyi family
IMCC20628_RS21990	COG2223	nitrite transmembrane transporter activity
IMCC20628_RS21995	COG3239	Fatty acid desaturase
IMCC20628_RS22000	COG1278	Cold shock
IMCC20628_RS22005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IMCC20628_RS22010	COG0625	glutathione transferase activity
IMCC20628_RS22015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMCC20628_RS22020	COG0142	geranyltranstransferase activity
IMCC20628_RS22025	COG2205	protein histidine kinase activity
IMCC20628_RS22025	COG0784	Response regulator, receiver
IMCC20628_RS22025	COG5002	protein histidine kinase activity
IMCC20628_RS22030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMCC20628_RS22035	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IMCC20628_RS22070	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC20628_RS22075	COG0174	glutamine synthetase
IMCC20628_RS22090	COG2197	response regulator
IMCC20628_RS22095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMCC20628_RS22110	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
IMCC20628_RS22115	COG0183	Belongs to the thiolase family
IMCC20628_RS22140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC20628_RS22145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IMCC20628_RS22150	COG1329	Transcriptional regulator
IMCC20628_RS22155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC20628_RS22165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IMCC20628_RS22185	COG0488	(ABC) transporter
IMCC20628_RS22200	COG3706	GGDEF domain
IMCC20628_RS22205	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IMCC20628_RS22255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC20628_RS22275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMCC20628_RS22280	COG2084	Dehydrogenase
IMCC20628_RS22290	COG2271	Major facilitator Superfamily
IMCC20628_RS22300	COG2963	transposase activity
IMCC20628_RS22305	COG2801	Transposase and inactivated derivatives
IMCC20628_RS22315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC20628_RS22360	COG1473	amidohydrolase
IMCC20628_RS22365	COG1686	Belongs to the peptidase S11 family
IMCC20628_RS22370	COG0523	cobalamin synthesis protein
IMCC20628_RS22380	COG3034	peptidoglycan biosynthetic process
IMCC20628_RS22385	COG0825	malonyl-CoA metabolic process
IMCC20628_RS22390	COG4974	Belongs to the 'phage' integrase family
IMCC20628_RS22400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMCC20628_RS22405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMCC20628_RS22410	COG4536	flavin adenine dinucleotide binding
IMCC20628_RS22440	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IMCC20628_RS22445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMCC20628_RS22470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC20628_RS22475	COG2226	methyltransferase
IMCC20628_RS22480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC20628_RS22485	COG0287	Prephenate dehydrogenase
IMCC20628_RS22515	COG2884	Cell division ATP-binding protein ftsE
IMCC20628_RS22540	COG0019	diaminopimelate decarboxylase activity
IMCC20628_RS22550	COG0165	Argininosuccinate lyase
IMCC20628_RS22555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC20628_RS22570	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC20628_RS22580	COG2086	electron transfer activity
IMCC20628_RS22600	COG0300	oxidoreductase activity
IMCC20628_RS22615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC20628_RS22635	COG1238	metal cluster binding
IMCC20628_RS22655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC20628_RS22670	COG0653	protein targeting
IMCC20628_RS22675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMCC20628_RS22680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMCC20628_RS22690	COG0494	nUDIX hydrolase
IMCC20628_RS22710	COG1040	competence protein
IMCC20628_RS22720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC20628_RS22735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC20628_RS22740	COG0527	aspartate kinase activity
IMCC20628_RS22750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMCC20628_RS22755	COG2890	protein-(glutamine-N5) methyltransferase activity
IMCC20628_RS22765	COG0542	response to heat
IMCC20628_RS22775	COG0739	heme binding
IMCC20628_RS22835	COG0439	Biotin carboxylase
IMCC20628_RS22970	COG0747	negative chemotaxis
IMCC20628_RS23090	COG2072	flavoprotein involved in K transport
IMCC20628_RS23120	COG0673	inositol 2-dehydrogenase activity
IMCC20628_RS23675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS23680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC20628_RS24030	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC20628_RS24160	COG3706	GGDEF domain
IMCC20628_RS24165	COG4191	Histidine kinase
IMCC20628_RS24165	COG0784	Response regulator, receiver
IMCC20628_RS24175	COG1652	LysM domain
IMCC20628_RS24225	COG3501	Rhs element vgr protein
IMCC20628_RS24280	COG3920	Histidine kinase
IMCC20628_RS24320	COG2197	response regulator
IMCC20628_RS24325	COG5002	protein histidine kinase activity
IMCC20628_RS24330	COG1309	transcriptional regulator
IMCC20628_RS24365	COG2199	diguanylate cyclase activity
IMCC20628_RS24395	COG5002	protein histidine kinase activity
IMCC20628_RS24395	COG5001	Diguanylate cyclase
IMCC20628_RS24395	COG3447	MASE1 domain protein