locus-tag	class	description
AS9A_RS00010	COG0592	DNA-directed DNA polymerase activity
AS9A_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS9A_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AS9A_RS00025	COG0187	DNA topoisomerase II activity
AS9A_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS9A_RS00110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS9A_RS00130	COG0705	Rhomboid family
AS9A_RS00155	COG0515	serine threonine protein kinase
AS9A_RS00155	COG2815	serine threonine protein kinase
AS9A_RS00160	COG0515	serine threonine protein kinase
AS9A_RS00165	COG0768	penicillin binding
AS9A_RS00180	COG1716	ATPase activity
AS9A_RS00185	COG1716	ATPase activity
AS9A_RS00195	COG0067	glutamate synthase
AS9A_RS00195	COG0070	glutamate synthase
AS9A_RS00195	COG0069	glutamate synthase activity
AS9A_RS00225	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS00245	COG1276	copper resistance
AS9A_RS00245	COG2372	response to copper ion
AS9A_RS00275	COG0129	dihydroxy-acid dehydratase activity
AS9A_RS00295	COG2239	Acts as a magnesium transporter
AS9A_RS00305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS9A_RS00315	COG1131	(ABC) transporter
AS9A_RS00325	COG2197	response regulator
AS9A_RS00350	COG1132	(ABC) transporter
AS9A_RS00380	COG1528	Iron-storage protein
AS9A_RS00385	COG1316	TRANSCRIPTIONal
AS9A_RS00410	COG0077	Prephenate dehydratase
AS9A_RS00450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AS9A_RS00470	COG0561	phosphatase activity
AS9A_RS00485	COG1216	Glycosyl transferase, family 2
AS9A_RS00490	COG0671	phosphoesterase, PA-phosphatase related
AS9A_RS00495	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AS9A_RS00500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS9A_RS00505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AS9A_RS00510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AS9A_RS00510	COG5479	isomerase activity
AS9A_RS00520	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AS9A_RS00525	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS00530	COG3321	synthase
AS9A_RS00530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS9A_RS00530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS9A_RS00535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS9A_RS00565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS9A_RS00575	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS00580	COG0277	FAD linked oxidase domain protein
AS9A_RS00605	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AS9A_RS00625	COG4585	Histidine kinase
AS9A_RS00630	COG2197	response regulator
AS9A_RS00635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS9A_RS00640	COG1120	ATPase activity
AS9A_RS00650	COG1088	dTDP-glucose 4,6-dehydratase activity
AS9A_RS00660	COG3433	isochorismatase activity
AS9A_RS00660	COG1535	isochorismatase
AS9A_RS00665	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS9A_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS00680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS00695	COG3433	isochorismatase activity
AS9A_RS00695	COG1535	isochorismatase
AS9A_RS00700	COG0477	Major facilitator Superfamily
AS9A_RS00705	COG2375	cellular response to nickel ion
AS9A_RS00715	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AS9A_RS00715	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AS9A_RS00720	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AS9A_RS00725	COG1216	Glycosyl transferase, family 2
AS9A_RS00750	COG1063	alcohol dehydrogenase
AS9A_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS00770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS00780	COG2072	flavoprotein involved in K transport
AS9A_RS00790	COG1053	succinate dehydrogenase
AS9A_RS00810	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS00820	COG2267	carboxylic ester hydrolase activity
AS9A_RS00830	COG0596	Alpha beta hydrolase
AS9A_RS00865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS9A_RS00905	COG1595	DNA-templated transcription, initiation
AS9A_RS00920	COG0596	Alpha beta hydrolase
AS9A_RS00940	COG0287	Prephenate dehydrogenase
AS9A_RS00950	COG0590	tRNA wobble adenosine to inosine editing
AS9A_RS00995	COG2409	Drug exporters of the RND superfamily
AS9A_RS01000	COG0343	queuine tRNA-ribosyltransferase activity
AS9A_RS01025	COG1968	undecaprenyl-diphosphatase activity
AS9A_RS01030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS9A_RS01055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS9A_RS01060	COG2226	methyltransferase
AS9A_RS01070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS9A_RS01085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS9A_RS01090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AS9A_RS01100	COG3442	glutamine amidotransferase
AS9A_RS01115	COG2212	antiporter activity
AS9A_RS01120	COG1863	multisubunit Na H antiporter MnhE subunit
AS9A_RS01125	COG0651	ATP synthesis coupled electron transport
AS9A_RS01135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS9A_RS01135	COG2111	Na H antiporter
AS9A_RS01140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS9A_RS01145	COG3268	Saccharopine dehydrogenase
AS9A_RS01175	COG0300	oxidoreductase activity
AS9A_RS01210	COG0569	domain protein
AS9A_RS01215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS9A_RS01225	COG1408	metallophosphoesterase
AS9A_RS01230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS9A_RS01255	COG0251	oxidation-reduction process
AS9A_RS01285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS9A_RS01315	COG0494	nUDIX hydrolase
AS9A_RS01325	COG0596	Alpha beta hydrolase
AS9A_RS01335	COG1733	regulation of RNA biosynthetic process
AS9A_RS01345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS9A_RS01395	COG1205	dead DEAH box helicase
AS9A_RS01395	COG1111	helicase
AS9A_RS01410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS9A_RS01410	COG1754	DNA topoisomerase type I activity
AS9A_RS01415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS9A_RS01420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS9A_RS01425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS9A_RS01425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS9A_RS01435	COG1105	Belongs to the carbohydrate kinase PfkB family
AS9A_RS01450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS9A_RS01490	COG1846	Transcriptional regulator
AS9A_RS01495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS9A_RS01505	COG2027	D-alanyl-D-alanine carboxypeptidase
AS9A_RS01515	COG0037	tRNA processing
AS9A_RS01520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AS9A_RS01525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS9A_RS01530	COG0302	gtp cyclohydrolase
AS9A_RS01540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS9A_RS01575	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AS9A_RS01580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AS9A_RS01635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS9A_RS01645	COG0542	response to heat
AS9A_RS01685	COG1194	a g-specific adenine glycosylase
AS9A_RS01690	COG0288	reversible hydration of carbon dioxide
AS9A_RS01700	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AS9A_RS01705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS9A_RS01715	COG1329	Transcriptional regulator
AS9A_RS01720	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AS9A_RS01730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS9A_RS01745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS9A_RS01750	COG0406	alpha-ribazole phosphatase activity
AS9A_RS01760	COG0785	Cytochrome C biogenesis protein
AS9A_RS01770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS9A_RS01800	COG1136	(ABC) transporter
AS9A_RS01800	COG0577	efflux transmembrane transporter activity
AS9A_RS01805	COG0577	efflux transmembrane transporter activity
AS9A_RS01805	COG1136	(ABC) transporter
AS9A_RS01815	COG2826	transposase and inactivated derivatives, IS30 family
AS9A_RS01850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS9A_RS01860	COG4948	Mandelate Racemase Muconate Lactonizing
AS9A_RS01865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS9A_RS01870	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AS9A_RS01880	COG0438	transferase activity, transferring glycosyl groups
AS9A_RS01885	COG2226	methyltransferase
AS9A_RS01890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS9A_RS01900	COG0142	geranyltranstransferase activity
AS9A_RS01905	COG0501	Belongs to the peptidase M48B family
AS9A_RS01910	COG1666	GTP binding
AS9A_RS01940	COG2030	dehydratase
AS9A_RS01945	COG0530	calcium, potassium:sodium antiporter activity
AS9A_RS01965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AS9A_RS01970	COG0081	regulation of translation
AS9A_RS01985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS9A_RS02010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS9A_RS02060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS9A_RS02065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS9A_RS02110	COG0085	RNA polymerase activity
AS9A_RS02135	COG0596	Alpha beta hydrolase
AS9A_RS02140	COG1024	Enoyl-CoA hydratase
AS9A_RS02155	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS02160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS9A_RS02195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AS9A_RS02200	COG0049	tRNA binding
AS9A_RS02205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS9A_RS02290	COG0051	transcription antitermination factor activity, RNA binding
AS9A_RS02300	COG0088	Forms part of the polypeptide exit tunnel
AS9A_RS02305	COG0089	rRNA binding
AS9A_RS02310	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS9A_RS02315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AS9A_RS02330	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS9A_RS02335	COG0255	Belongs to the universal ribosomal protein uL29 family
AS9A_RS02340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AS9A_RS02345	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS9A_RS02350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AS9A_RS02360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS9A_RS02365	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AS9A_RS02375	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AS9A_RS02385	COG1841	ribosomal large subunit assembly
AS9A_RS02400	COG0563	adenylate kinase activity
AS9A_RS02410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AS9A_RS02415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS9A_RS02420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AS9A_RS02425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS9A_RS02430	COG0202	RNA polymerase activity
AS9A_RS02465	COG4129	membrane
AS9A_RS02485	COG1234	tRNA 3'-trailer cleavage
AS9A_RS02550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AS9A_RS02580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS02590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS9A_RS02600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS9A_RS02615	COG0352	thiamine-phosphate diphosphorylase activity
AS9A_RS02620	COG2022	thiamine diphosphate biosynthetic process
AS9A_RS02620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS9A_RS02630	COG2022	thiamine diphosphate biosynthetic process
AS9A_RS02645	COG2234	aminopeptidase activity
AS9A_RS02650	COG4607	ABC-type enterochelin transport system periplasmic component
AS9A_RS02660	COG0351	phosphomethylpyrimidine kinase
AS9A_RS02665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AS9A_RS02700	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS9A_RS02710	COG2212	antiporter activity
AS9A_RS02720	COG0651	ATP synthesis coupled electron transport
AS9A_RS02725	COG1006	Multisubunit Na H antiporter MnhC subunit
AS9A_RS02730	COG2111	Na H antiporter
AS9A_RS02730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS9A_RS02740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS9A_RS02750	COG0688	phosphatidylethanolamine metabolic process
AS9A_RS02780	COG0647	UMP catabolic process
AS9A_RS02790	COG0459	protein refolding
AS9A_RS02795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS9A_RS02805	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS9A_RS02855	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS02950	COG2224	Isocitrate lyase
AS9A_RS02960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS9A_RS02965	COG2733	membrane
AS9A_RS02990	COG0789	Transcriptional regulator
AS9A_RS02995	COG0596	Alpha beta hydrolase
AS9A_RS03005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AS9A_RS03025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS9A_RS03040	COG0438	transferase activity, transferring glycosyl groups
AS9A_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS03060	COG0588	phosphoglycerate mutase activity
AS9A_RS03065	COG5002	protein histidine kinase activity
AS9A_RS03080	COG0248	Ppx GppA phosphatase
AS9A_RS03090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS9A_RS03120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AS9A_RS03125	COG0181	hydroxymethylbilane synthase activity
AS9A_RS03130	COG1587	Uroporphyrinogen-III synthase
AS9A_RS03130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS9A_RS03135	COG0113	porphobilinogen synthase activity
AS9A_RS03160	COG1984	allophanate hydrolase subunit 2
AS9A_RS03165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS9A_RS03175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS9A_RS03180	COG1121	(ABC) transporter
AS9A_RS03190	COG1609	Transcriptional regulator
AS9A_RS03210	COG1132	(ABC) transporter
AS9A_RS03215	COG1132	(ABC) transporter
AS9A_RS03235	COG5522	Integral membrane protein (intg_mem_TP0381)
AS9A_RS03265	COG0537	adenosine 5'-monophosphoramidase activity
AS9A_RS03275	COG0436	Aminotransferase
AS9A_RS03285	COG2357	RelA SpoT domain protein
AS9A_RS03290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS9A_RS03300	COG0537	adenosine 5'-monophosphoramidase activity
AS9A_RS03305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS9A_RS03315	COG0386	Belongs to the glutathione peroxidase family
AS9A_RS03330	COG1136	(ABC) transporter
AS9A_RS03345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS9A_RS03350	COG0047	phosphoribosylformylglycinamidine synthase activity
AS9A_RS03355	COG5650	phosphatidylinositol metabolic process
AS9A_RS03375	COG0714	Associated with various cellular activities
AS9A_RS03390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS9A_RS03420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AS9A_RS03435	COG0354	folic acid binding
AS9A_RS03450	COG0431	NADPH-dependent FMN reductase
AS9A_RS03455	COG0477	Major facilitator Superfamily
AS9A_RS03460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS9A_RS03465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS9A_RS03470	COG1271	oxidase subunit
AS9A_RS03475	COG1294	oxidase, subunit
AS9A_RS03480	COG4988	ABC transporter
AS9A_RS03485	COG1132	(ABC) transporter
AS9A_RS03490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS9A_RS03500	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS03525	COG2267	carboxylic ester hydrolase activity
AS9A_RS03530	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS03535	COG1024	Enoyl-CoA hydratase
AS9A_RS03540	COG1309	transcriptional regulator
AS9A_RS03575	COG2072	flavoprotein involved in K transport
AS9A_RS03585	COG3012	SEC-C Motif Domain Protein
AS9A_RS03590	COG3622	Belongs to the hyi family
AS9A_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS03610	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AS9A_RS03625	COG2897	thiosulfate sulfurtransferase activity
AS9A_RS03645	COG0745	RESPONSE REGULATOR receiver
AS9A_RS03650	COG0456	acetyltransferase
AS9A_RS03650	COG0454	-acetyltransferase
AS9A_RS03655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS9A_RS03670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS9A_RS03745	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS03750	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS03755	COG0183	Belongs to the thiolase family
AS9A_RS03765	COG1309	transcriptional regulator
AS9A_RS03770	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS03785	COG1024	Enoyl-CoA hydratase
AS9A_RS03815	COG0604	alcohol dehydrogenase
AS9A_RS03815	COG3321	synthase
AS9A_RS03835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS03850	COG2197	response regulator
AS9A_RS03855	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS03875	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS03885	COG0183	Belongs to the thiolase family
AS9A_RS03895	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AS9A_RS03925	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS03985	COG1162	GTPase activity
AS9A_RS04015	COG1546	Belongs to the CinA family
AS9A_RS04015	COG1058	Belongs to the CinA family
AS9A_RS04045	COG1652	LysM domain
AS9A_RS04060	COG3304	Inner membrane component domain
AS9A_RS04065	COG1278	Cold shock
AS9A_RS04075	COG2814	Major facilitator Superfamily
AS9A_RS04090	COG0671	phosphoesterase, PA-phosphatase related
AS9A_RS04110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS9A_RS04145	COG0545	Peptidyl-prolyl cis-trans isomerase
AS9A_RS04155	COG0415	Belongs to the DNA photolyase family
AS9A_RS04160	COG2226	methyltransferase
AS9A_RS04215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS9A_RS04225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AS9A_RS04265	COG3275	phosphorelay sensor kinase activity
AS9A_RS04270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AS9A_RS04275	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AS9A_RS04290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS9A_RS04300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS9A_RS04305	COG2272	Belongs to the type-B carboxylesterase lipase family
AS9A_RS04330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AS9A_RS04355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS9A_RS04365	COG1309	transcriptional regulator
AS9A_RS04370	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04380	COG2267	carboxylic ester hydrolase activity
AS9A_RS04385	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04390	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04395	COG2030	dehydratase
AS9A_RS04435	COG0477	Major facilitator Superfamily
AS9A_RS04440	COG2030	dehydratase
AS9A_RS04465	COG1053	succinate dehydrogenase
AS9A_RS04470	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04475	COG2267	carboxylic ester hydrolase activity
AS9A_RS04480	COG0346	lactoylglutathione lyase activity
AS9A_RS04490	COG0300	oxidoreductase activity
AS9A_RS04500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS9A_RS04515	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS04520	COG0183	Belongs to the thiolase family
AS9A_RS04545	COG4221	oxidoreductase activity
AS9A_RS04550	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04555	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04560	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS9A_RS04570	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS04575	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04580	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS04585	COG1309	transcriptional regulator
AS9A_RS04590	COG0183	Belongs to the thiolase family
AS9A_RS04615	COG1609	Transcriptional regulator
AS9A_RS04640	COG1024	Enoyl-CoA hydratase
AS9A_RS04645	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS04650	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS04670	COG0183	Belongs to the thiolase family
AS9A_RS04675	COG2124	cytochrome p450
AS9A_RS04680	COG4638	Rieske (2fe-2S)
AS9A_RS04685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS9A_RS04705	COG0285	dihydrofolate synthase activity
AS9A_RS04720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS9A_RS04725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS9A_RS04735	COG1414	Transcriptional regulator
AS9A_RS04780	COG0596	Alpha beta hydrolase
AS9A_RS04795	COG1024	Enoyl-CoA hydratase
AS9A_RS04805	COG2070	2-Nitropropane dioxygenase
AS9A_RS04825	COG0509	glycine decarboxylation via glycine cleavage system
AS9A_RS04850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS9A_RS04855	COG1802	Transcriptional regulator
AS9A_RS04860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS9A_RS04880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS9A_RS04890	COG1414	Transcriptional regulator
AS9A_RS04905	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AS9A_RS04910	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04915	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS04950	COG3971	2-oxopent-4-enoate hydratase activity
AS9A_RS04955	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS9A_RS04955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS9A_RS04960	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS9A_RS04985	COG1653	transport
AS9A_RS05005	COG1376	ErfK ybiS ycfS ynhG family protein
AS9A_RS05025	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS05030	COG0300	oxidoreductase activity
AS9A_RS05045	COG1902	pentaerythritol trinitrate reductase activity
AS9A_RS05045	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS9A_RS05065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS9A_RS05075	COG1595	DNA-templated transcription, initiation
AS9A_RS05085	COG1295	ribonuclease BN
AS9A_RS05120	COG3336	cytochrome c oxidase
AS9A_RS05140	COG2902	Dehydrogenase
AS9A_RS05160	COG0668	transmembrane transport
AS9A_RS05175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AS9A_RS05185	COG2226	methyltransferase
AS9A_RS05210	COG4770	biotin carboxylase activity
AS9A_RS05225	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS9A_RS05230	COG0698	ribose 5-phosphate isomerase
AS9A_RS05270	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS9A_RS05275	COG0740	serine-type endopeptidase activity
AS9A_RS05280	COG0740	serine-type endopeptidase activity
AS9A_RS05290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS9A_RS05295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS9A_RS05300	COG4946	Tricorn protease homolog
AS9A_RS05300	COG1506	peptidase
AS9A_RS05300	COG0823	Involved in the tonB-independent uptake of proteins
AS9A_RS05320	COG4172	Belongs to the ABC transporter superfamily
AS9A_RS05330	COG1309	transcriptional regulator
AS9A_RS05345	COG1073	alpha beta
AS9A_RS05380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS9A_RS05400	COG2267	carboxylic ester hydrolase activity
AS9A_RS05415	COG0525	valine-tRNA ligase activity
AS9A_RS05420	COG0285	dihydrofolate synthase activity
AS9A_RS05430	COG0105	UTP biosynthetic process
AS9A_RS05435	COG1530	ribonuclease E activity
AS9A_RS05435	COG1530	ribonuclease E activity
AS9A_RS05450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS9A_RS05460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS9A_RS05465	COG0798	PFAM Bile acid sodium symporter
AS9A_RS05480	COG1917	Cupin 2, conserved barrel domain protein
AS9A_RS05485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS9A_RS05490	COG0456	acetyltransferase
AS9A_RS05495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS9A_RS05500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS9A_RS05505	COG0542	response to heat
AS9A_RS05520	COG0799	negative regulation of ribosome biogenesis
AS9A_RS05525	COG0406	alpha-ribazole phosphatase activity
AS9A_RS05530	COG2755	lipolytic protein G-D-S-L family
AS9A_RS05540	COG1555	photosystem II stabilization
AS9A_RS05545	COG1234	tRNA 3'-trailer cleavage
AS9A_RS05575	COG1305	Transglutaminase-like
AS9A_RS05585	COG0481	GTPase activity
AS9A_RS05600	COG0384	phenazine biosynthesis protein PhzF
AS9A_RS05605	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS05665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AS9A_RS05690	COG0657	acetylesterase activity
AS9A_RS05700	COG2070	2-Nitropropane dioxygenase
AS9A_RS05710	COG1652	LysM domain
AS9A_RS05715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS9A_RS05720	COG3387	PFAM Glycoside hydrolase 15-related
AS9A_RS05730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AS9A_RS05740	COG4208	sulfate ABC transporter
AS9A_RS05745	COG3842	ATPase activity
AS9A_RS05780	COG1420	regulation of RNA biosynthetic process
AS9A_RS05785	COG0484	heat shock protein binding
AS9A_RS05825	COG0573	inorganic phosphate transmembrane transporter activity
AS9A_RS05835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS9A_RS05840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS9A_RS05850	COG1381	Involved in DNA repair and RecF pathway recombination
AS9A_RS05855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS9A_RS05870	COG0423	glycine-tRNA ligase activity
AS9A_RS05885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AS9A_RS05890	COG0358	DNA primase activity
AS9A_RS05940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS9A_RS06000	COG1136	(ABC) transporter
AS9A_RS06030	COG3323	Protein of unknown function (DUF1653)
AS9A_RS06030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS9A_RS06070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AS9A_RS06080	COG0174	glutamine synthetase
AS9A_RS06085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AS9A_RS06095	COG0174	glutamine synthetase
AS9A_RS06110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS9A_RS06115	COG0321	lipoyl(octanoyl) transferase activity
AS9A_RS06120	COG1090	epimerase
AS9A_RS06125	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS9A_RS06135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS9A_RS06140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS9A_RS06145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS9A_RS06150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AS9A_RS06155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AS9A_RS06175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS9A_RS06185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS9A_RS06195	COG0701	Predicted permease
AS9A_RS06220	COG1845	cytochrome c oxidase, subunit III
AS9A_RS06230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS9A_RS06280	COG0003	Pfam Anion-transporting ATPase
AS9A_RS06290	COG1940	carbohydrate kinase activity
AS9A_RS06305	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AS9A_RS06335	COG0142	geranyltranstransferase activity
AS9A_RS06385	COG0275	rRNA processing
AS9A_RS06395	COG0768	penicillin binding
AS9A_RS06415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS9A_RS06430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS9A_RS06440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS9A_RS06455	COG1799	cell septum assembly
AS9A_RS06465	COG3599	regulation of cell shape
AS9A_RS06480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS9A_RS06495	COG0297	glycogen (starch) synthase activity
AS9A_RS06500	COG0366	Alpha amylase catalytic
AS9A_RS06505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS9A_RS06510	COG2957	Belongs to the agmatine deiminase family
AS9A_RS06545	COG0300	oxidoreductase activity
AS9A_RS06550	COG2072	flavoprotein involved in K transport
AS9A_RS06565	COG2311	Membrane
AS9A_RS06570	COG1929	Belongs to the glycerate kinase type-1 family
AS9A_RS06595	COG2902	Dehydrogenase
AS9A_RS06605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS9A_RS06620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AS9A_RS06645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS9A_RS06695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS9A_RS06700	COG0156	8-amino-7-oxononanoate synthase activity
AS9A_RS06705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS9A_RS06710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS9A_RS06735	COG2264	protein methyltransferase activity
AS9A_RS06775	COG0438	transferase activity, transferring glycosyl groups
AS9A_RS06815	COG3387	PFAM Glycoside hydrolase 15-related
AS9A_RS06825	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS9A_RS06855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS9A_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS06880	COG1609	Transcriptional regulator
AS9A_RS06895	COG0477	Major facilitator Superfamily
AS9A_RS06900	COG1309	transcriptional regulator
AS9A_RS06915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AS9A_RS06920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS9A_RS06930	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AS9A_RS06950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS9A_RS06955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS9A_RS06960	COG0131	Imidazoleglycerol-phosphate dehydratase
AS9A_RS06970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AS9A_RS06985	COG0483	inositol monophosphate 1-phosphatase activity
AS9A_RS06990	COG0107	imidazoleglycerol-phosphate synthase activity
AS9A_RS06995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS9A_RS07005	COG1942	4-Oxalocrotonate Tautomerase
AS9A_RS07025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS9A_RS07045	COG0159	tryptophan synthase activity
AS9A_RS07050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS9A_RS07060	COG0070	glutamate synthase
AS9A_RS07060	COG0069	glutamate synthase activity
AS9A_RS07060	COG0067	glutamate synthase
AS9A_RS07075	COG1525	nuclease
AS9A_RS07085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS9A_RS07130	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS9A_RS07155	COG0473	3-isopropylmalate dehydrogenase activity
AS9A_RS07160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS9A_RS07175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS9A_RS07180	COG0539	negative regulation of cytoplasmic translation
AS9A_RS07185	COG0237	dephospho-CoA kinase activity
AS9A_RS07185	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS9A_RS07210	COG3973	AAA domain
AS9A_RS07220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS9A_RS07235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS9A_RS07245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS9A_RS07250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS9A_RS07255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS9A_RS07260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS9A_RS07260	COG0072	phenylalanine-tRNA ligase activity
AS9A_RS07270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AS9A_RS07275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AS9A_RS07280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AS9A_RS07285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS9A_RS07305	COG0165	Argininosuccinate lyase
AS9A_RS07315	COG2835	tetraacyldisaccharide 4'-kinase activity
AS9A_RS07315	COG1663	tetraacyldisaccharide 4'-kinase activity
AS9A_RS07325	COG2094	Belongs to the DNA glycosylase MPG family
AS9A_RS07330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS9A_RS07355	COG0647	UMP catabolic process
AS9A_RS07390	COG0504	CTP synthase activity
AS9A_RS07395	COG0494	nUDIX hydrolase
AS9A_RS07415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AS9A_RS07420	COG1187	pseudouridine synthase activity
AS9A_RS07425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AS9A_RS07430	COG1160	GTP binding
AS9A_RS07445	COG2323	membrane
AS9A_RS07460	COG0477	Major facilitator Superfamily
AS9A_RS07490	COG1320	monovalent cation:proton antiporter activity
AS9A_RS07495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS9A_RS07495	COG2111	Na H antiporter
AS9A_RS07505	COG0651	ATP synthesis coupled electron transport
AS9A_RS07510	COG0651	ATP synthesis coupled electron transport
AS9A_RS07515	COG0651	ATP synthesis coupled electron transport
AS9A_RS07525	COG2814	Major facilitator Superfamily
AS9A_RS07550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AS9A_RS07570	COG0228	four-way junction DNA binding
AS9A_RS07580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AS9A_RS07585	COG0336	Belongs to the RNA methyltransferase TrmD family
AS9A_RS07600	COG0681	Belongs to the peptidase S26 family
AS9A_RS07615	COG0792	nuclease activity
AS9A_RS07630	COG4974	Belongs to the 'phage' integrase family
AS9A_RS07645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AS9A_RS07650	COG0528	UMP kinase activity
AS9A_RS07665	COG0500	methyltransferase
AS9A_RS07670	COG5416	Lipopolysaccharide assembly protein A domain
AS9A_RS07685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AS9A_RS07700	COG0456	acetyltransferase
AS9A_RS07725	COG0277	FAD linked oxidase domain protein
AS9A_RS07730	COG1597	lipid kinase activity
AS9A_RS07740	COG1131	(ABC) transporter
AS9A_RS07775	COG0579	oxidoreductase
AS9A_RS07800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS9A_RS07800	COG1648	precorrin-2 dehydrogenase activity
AS9A_RS07810	COG3022	response to hydroperoxide
AS9A_RS07815	COG0442	prolyl-tRNA aminoacylation
AS9A_RS07820	COG4122	O-methyltransferase activity
AS9A_RS07850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AS9A_RS07855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS9A_RS07865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS9A_RS07870	COG2977	Belongs to the P-Pant transferase superfamily
AS9A_RS07875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AS9A_RS07885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS9A_RS07890	COG1121	(ABC) transporter
AS9A_RS07910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AS9A_RS07925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AS9A_RS07955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS9A_RS07965	COG4585	Histidine kinase
AS9A_RS07990	COG0772	Belongs to the SEDS family
AS9A_RS08025	COG0471	metal ion transport
AS9A_RS08030	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS08050	COG1115	amino acid carrier protein
AS9A_RS08070	COG0366	Alpha amylase catalytic
AS9A_RS08075	COG3842	ATPase activity
AS9A_RS08080	COG3833	ABC-type maltose transport systems, permease component
AS9A_RS08085	COG1175	transmembrane transport
AS9A_RS08095	COG0366	Alpha amylase catalytic
AS9A_RS08100	COG1609	Transcriptional regulator
AS9A_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS08120	COG1309	transcriptional regulator
AS9A_RS08125	COG2072	flavoprotein involved in K transport
AS9A_RS08155	COG4941	Belongs to the sigma-70 factor family
AS9A_RS08165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS9A_RS08185	COG1842	Phage shock protein A
AS9A_RS08205	COG0596	Alpha beta hydrolase
AS9A_RS08220	COG2137	regulation of response to DNA damage stimulus
AS9A_RS08250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS9A_RS08260	COG1196	nuclear chromosome segregation
AS9A_RS08270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AS9A_RS08275	COG1609	Transcriptional regulator
AS9A_RS08290	COG0395	ABC-type sugar transport system, permease component
AS9A_RS08300	COG3842	ATPase activity
AS9A_RS08305	COG1253	flavin adenine dinucleotide binding
AS9A_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS08325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS9A_RS08350	COG1643	Atp-dependent helicase
AS9A_RS08355	COG2040	homocysteine
AS9A_RS08365	COG0183	Belongs to the thiolase family
AS9A_RS08370	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS08400	COG2072	flavoprotein involved in K transport
AS9A_RS08455	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS9A_RS08470	COG1490	D-aminoacyl-tRNA deacylase activity
AS9A_RS08475	COG2890	protein-(glutamine-N5) methyltransferase activity
AS9A_RS08510	COG0483	inositol monophosphate 1-phosphatase activity
AS9A_RS08530	COG0756	dUTP diphosphatase activity
AS9A_RS08550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS9A_RS08555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS9A_RS08575	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AS9A_RS08590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS9A_RS08715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS9A_RS08730	COG1560	Kdo2-lipid A biosynthetic process
AS9A_RS08735	COG0438	transferase activity, transferring glycosyl groups
AS9A_RS08740	COG1051	belongs to the nudix hydrolase family
AS9A_RS08745	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AS9A_RS08750	COG1946	Acyl-CoA thioesterase
AS9A_RS08755	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AS9A_RS08760	COG0217	transcriptional regulatory protein
AS9A_RS08775	COG2255	four-way junction helicase activity
AS9A_RS08785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS9A_RS08790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS9A_RS08795	COG0747	negative chemotaxis
AS9A_RS08800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS9A_RS08805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS9A_RS08815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS9A_RS08855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS9A_RS08865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AS9A_RS08900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS9A_RS08905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AS9A_RS08915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS9A_RS08930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS9A_RS08945	COG0006	proline dipeptidase activity
AS9A_RS08950	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS9A_RS08955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS9A_RS08980	COG0505	Belongs to the CarA family
AS9A_RS08990	COG0284	orotidine-5'-phosphate decarboxylase activity
AS9A_RS09000	COG0194	GDP metabolic process
AS9A_RS09015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AS9A_RS09050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS9A_RS09095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS9A_RS09095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS9A_RS09110	COG0322	excinuclease ABC activity
AS9A_RS09115	COG1660	Displays ATPase and GTPase activities
AS9A_RS09125	COG1481	regulation of sporulation
AS9A_RS09135	COG0126	phosphoglycerate kinase activity
AS9A_RS09140	COG0149	triose-phosphate isomerase activity
AS9A_RS09160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS9A_RS09170	COG0109	protoheme IX farnesyltransferase activity
AS9A_RS09195	COG1131	(ABC) transporter
AS9A_RS09215	COG0719	Fe-S assembly protein
AS9A_RS09220	COG0396	ATPase activity
AS9A_RS09225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS9A_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS09250	COG0488	(ABC) transporter
AS9A_RS09260	COG1309	transcriptional regulator
AS9A_RS09265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS9A_RS09275	COG3883	PFAM NLP P60 protein
AS9A_RS09275	COG0791	NLP P60 protein
AS9A_RS09280	COG0714	Associated with various cellular activities
AS9A_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS09300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AS9A_RS09305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AS9A_RS09330	COG2072	flavoprotein involved in K transport
AS9A_RS09365	COG3845	ABC transporter
AS9A_RS09415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AS9A_RS09440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS9A_RS09450	COG0167	dihydroorotate dehydrogenase activity
AS9A_RS09475	COG1968	undecaprenyl-diphosphatase activity
AS9A_RS09495	COG0215	cysteine-tRNA ligase activity
AS9A_RS09510	COG0646	methionine synthase
AS9A_RS09510	COG1410	methionine synthase
AS9A_RS09535	COG0463	Glycosyl transferase, family 2
AS9A_RS09540	COG0375	protein maturation
AS9A_RS09560	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AS9A_RS09595	COG0298	carbon dioxide binding
AS9A_RS09600	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AS9A_RS09605	COG0298	carbon dioxide binding
AS9A_RS09610	COG0409	Hydrogenase expression formation protein
AS9A_RS09630	COG0140	phosphoribosyl-ATP diphosphatase activity
AS9A_RS09635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AS9A_RS09675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS9A_RS09710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS9A_RS09720	COG1222	aaa ATPase
AS9A_RS09735	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AS9A_RS09760	COG2378	regulation of single-species biofilm formation
AS9A_RS09785	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS09810	COG0300	oxidoreductase activity
AS9A_RS09835	COG3757	hydrolase, family 25
AS9A_RS09850	COG2217	Heavy metal translocating P-type atpase
AS9A_RS09870	COG1937	Protein conserved in bacteria
AS9A_RS09900	COG0477	Major facilitator Superfamily
AS9A_RS09905	COG2197	response regulator
AS9A_RS09915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS9A_RS09925	COG3842	ATPase activity
AS9A_RS09935	COG2267	carboxylic ester hydrolase activity
AS9A_RS09950	COG4585	Histidine kinase
AS9A_RS09955	COG2197	response regulator
AS9A_RS09965	COG1228	amidohydrolase
AS9A_RS09975	COG0463	Glycosyl transferase, family 2
AS9A_RS09995	COG0402	S-adenosylhomocysteine deaminase activity
AS9A_RS10005	COG0596	Alpha beta hydrolase
AS9A_RS10010	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS9A_RS10010	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS9A_RS10015	COG0501	Belongs to the peptidase M48B family
AS9A_RS10020	COG1704	LemA family
AS9A_RS10025	COG0831	urea catabolic process
AS9A_RS10030	COG0832	Belongs to the urease beta subunit family
AS9A_RS10035	COG0804	urea catabolic process
AS9A_RS10040	COG0830	nickel cation binding
AS9A_RS10045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AS9A_RS10050	COG0829	nickel cation binding
AS9A_RS10055	COG5285	phytanoyl-CoA dioxygenase
AS9A_RS10095	COG1126	abc transporter atp-binding protein
AS9A_RS10100	COG0765	amino acid transport
AS9A_RS10105	COG0765	amino acid transport
AS9A_RS10110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS9A_RS10135	COG1140	nitrate reductase beta subunit
AS9A_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS10160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS9A_RS10160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS9A_RS10170	COG1132	(ABC) transporter
AS9A_RS10175	COG1132	(ABC) transporter
AS9A_RS10195	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AS9A_RS10200	COG0121	glutamine amidotransferase
AS9A_RS10205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS9A_RS10210	COG3572	ergothioneine biosynthetic process
AS9A_RS10225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS9A_RS10250	COG0574	Belongs to the PEP-utilizing enzyme family
AS9A_RS10250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS9A_RS10265	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS9A_RS10335	COG2814	Major facilitator Superfamily
AS9A_RS10340	COG0583	DNA-binding transcription factor activity
AS9A_RS10345	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AS9A_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS10370	COG3467	pyridoxamine 5'-phosphate
AS9A_RS10380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS10410	COG3284	Transcriptional regulator
AS9A_RS10415	COG0277	FAD linked oxidase domain protein
AS9A_RS10425	COG0459	protein refolding
AS9A_RS10430	COG1063	alcohol dehydrogenase
AS9A_RS10455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS9A_RS10460	COG3350	monooxygenase activity
AS9A_RS10475	COG1522	sequence-specific DNA binding
AS9A_RS10525	COG1064	alcohol dehydrogenase
AS9A_RS10600	COG3547	Transposase (IS116 IS110 IS902 family)
AS9A_RS10615	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS10620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS9A_RS10635	COG1024	Enoyl-CoA hydratase
AS9A_RS10645	COG0183	Belongs to the thiolase family
AS9A_RS10655	COG0477	Major facilitator Superfamily
AS9A_RS10670	COG1902	pentaerythritol trinitrate reductase activity
AS9A_RS10670	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS9A_RS10700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS10760	COG0596	Alpha beta hydrolase
AS9A_RS10765	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS10770	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS10780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS10785	COG2017	converts alpha-aldose to the beta-anomer
AS9A_RS10790	COG2160	L-arabinose isomerase activity
AS9A_RS10805	COG1609	Transcriptional regulator
AS9A_RS10820	COG4213	ABC transporter substrate-binding protein
AS9A_RS10825	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS9A_RS10830	COG1129	ABC transporter
AS9A_RS10855	COG0251	oxidation-reduction process
AS9A_RS10865	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS10910	COG2124	cytochrome p450
AS9A_RS10930	COG4221	oxidoreductase activity
AS9A_RS10940	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS10945	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS10950	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS10985	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS9A_RS10985	COG1902	pentaerythritol trinitrate reductase activity
AS9A_RS10990	COG4689	acetoacetate decarboxylase
AS9A_RS10995	COG4221	oxidoreductase activity
AS9A_RS11000	COG2072	flavoprotein involved in K transport
AS9A_RS11010	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS11010	COG0604	alcohol dehydrogenase
AS9A_RS11010	COG3321	synthase
AS9A_RS11025	COG2226	methyltransferase
AS9A_RS11065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS9A_RS11070	COG1120	ATPase activity
AS9A_RS11120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS9A_RS11125	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AS9A_RS11130	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AS9A_RS11140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS9A_RS11145	COG4585	Histidine kinase
AS9A_RS11210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS9A_RS11220	COG1309	transcriptional regulator
AS9A_RS11225	COG0477	Major facilitator Superfamily
AS9A_RS11255	COG0531	amino acid
AS9A_RS11260	COG2771	luxR family
AS9A_RS11275	COG1472	Belongs to the glycosyl hydrolase 3 family
AS9A_RS11295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS11300	COG2267	carboxylic ester hydrolase activity
AS9A_RS11310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS9A_RS11325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS9A_RS11340	COG3795	YCII-related domain
AS9A_RS11345	COG4941	Belongs to the sigma-70 factor family
AS9A_RS11355	COG0745	RESPONSE REGULATOR receiver
AS9A_RS11360	COG2205	protein histidine kinase activity
AS9A_RS11390	COG4681	YaeQ
AS9A_RS11400	COG0642	Histidine kinase
AS9A_RS11400	COG3850	Histidine kinase
AS9A_RS11405	COG0745	RESPONSE REGULATOR receiver
AS9A_RS11410	COG0471	metal ion transport
AS9A_RS11415	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS11450	COG0243	molybdopterin cofactor binding
AS9A_RS11450	COG0243	molybdopterin cofactor binding
AS9A_RS11460	COG1757	Na H antiporter
AS9A_RS11465	COG2267	carboxylic ester hydrolase activity
AS9A_RS11490	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS11540	COG2508	Transcriptional regulator
AS9A_RS11565	COG1595	DNA-templated transcription, initiation
AS9A_RS11570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS9A_RS11570	COG2169	Transcriptional regulator
AS9A_RS11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS9A_RS11595	COG1126	abc transporter atp-binding protein
AS9A_RS11600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS9A_RS11605	COG0765	amino acid transport
AS9A_RS11610	COG0765	amino acid transport
AS9A_RS11615	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS11630	COG2072	flavoprotein involved in K transport
AS9A_RS11645	COG0657	acetylesterase activity
AS9A_RS11650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS9A_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS11675	COG1268	BioY protein
AS9A_RS11680	COG1122	ATPase activity
AS9A_RS11700	COG0673	inositol 2-dehydrogenase activity
AS9A_RS11720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS9A_RS11740	COG1366	Belongs to the anti-sigma-factor antagonist family
AS9A_RS11745	COG1215	transferase activity, transferring glycosyl groups
AS9A_RS11755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AS9A_RS11755	COG4124	Belongs to the glycosyl hydrolase 26 family
AS9A_RS11760	COG4941	Belongs to the sigma-70 factor family
AS9A_RS11765	COG3795	YCII-related domain
AS9A_RS11780	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS9A_RS11820	COG0596	Alpha beta hydrolase
AS9A_RS11835	COG2226	methyltransferase
AS9A_RS11840	COG1917	Cupin 2, conserved barrel domain protein
AS9A_RS11840	COG4977	sequence-specific DNA binding
AS9A_RS11855	COG2267	carboxylic ester hydrolase activity
AS9A_RS11885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS9A_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS11900	COG3226	Transcriptional regulator
AS9A_RS11920	COG2337	Toxic component of a toxin-antitoxin (TA) module
AS9A_RS11925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS9A_RS11940	COG0514	ATP-dependent DNA helicase (RecQ)
AS9A_RS11945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS9A_RS11945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS9A_RS11955	COG0183	Belongs to the thiolase family
AS9A_RS11960	COG1470	cell adhesion involved in biofilm formation
AS9A_RS11965	COG0076	glutamate decarboxylase activity
AS9A_RS11970	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AS9A_RS11985	COG1309	transcriptional regulator
AS9A_RS11990	COG0328	RNA-DNA hybrid ribonuclease activity
AS9A_RS11995	COG1024	Enoyl-CoA hydratase
AS9A_RS12005	COG0167	dihydroorotate dehydrogenase activity
AS9A_RS12110	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS12115	COG1116	anion transmembrane transporter activity
AS9A_RS12120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS9A_RS12135	COG1846	Transcriptional regulator
AS9A_RS12155	COG4941	Belongs to the sigma-70 factor family
AS9A_RS12195	COG0326	Molecular chaperone. Has ATPase activity
AS9A_RS12250	COG0247	lactate metabolic process
AS9A_RS12250	COG0277	FAD linked oxidase domain protein
AS9A_RS12275	COG0596	Alpha beta hydrolase
AS9A_RS12280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AS9A_RS12310	COG0693	protein deglycase activity
AS9A_RS12325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS9A_RS12400	COG2132	Multicopper oxidase
AS9A_RS12420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS9A_RS12425	COG2814	Major facilitator Superfamily
AS9A_RS12440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS9A_RS12465	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS12495	COG0277	FAD linked oxidase domain protein
AS9A_RS12500	COG2132	Multicopper oxidase
AS9A_RS12505	COG3104	oligopeptide transport
AS9A_RS12515	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS12555	COG4221	oxidoreductase activity
AS9A_RS12560	COG2508	Transcriptional regulator
AS9A_RS12595	COG1024	Enoyl-CoA hydratase
AS9A_RS12600	COG0477	Major facilitator Superfamily
AS9A_RS12630	COG0702	epimerase
AS9A_RS12645	COG1131	(ABC) transporter
AS9A_RS12655	COG1476	TRANSCRIPTIONal
AS9A_RS12660	COG4608	Belongs to the ABC transporter superfamily
AS9A_RS12670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS9A_RS12675	COG0601	transmembrane transport
AS9A_RS12690	COG1278	Cold shock
AS9A_RS12720	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS12725	COG1802	Transcriptional regulator
AS9A_RS12730	COG3383	formate dehydrogenase (NAD+) activity
AS9A_RS12745	COG1024	Enoyl-CoA hydratase
AS9A_RS12755	COG1024	Enoyl-CoA hydratase
AS9A_RS12755	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS9A_RS12760	COG0183	Belongs to the thiolase family
AS9A_RS12765	COG1309	transcriptional regulator
AS9A_RS12800	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS12830	COG2890	protein-(glutamine-N5) methyltransferase activity
AS9A_RS12835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS9A_RS12840	COG1253	flavin adenine dinucleotide binding
AS9A_RS12860	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS9A_RS12865	COG0714	Associated with various cellular activities
AS9A_RS12935	COG3384	dioxygenase
AS9A_RS12940	COG0708	Exodeoxyribonuclease III
AS9A_RS13005	COG1131	(ABC) transporter
AS9A_RS13040	COG1252	NADH dehydrogenase
AS9A_RS13045	COG1595	DNA-templated transcription, initiation
AS9A_RS13120	COG1819	glycosyl
AS9A_RS13135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS13135	COG3321	synthase
AS9A_RS13140	COG3321	synthase
AS9A_RS13140	COG0604	alcohol dehydrogenase
AS9A_RS13185	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS13190	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS13195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS9A_RS13200	COG2902	Dehydrogenase
AS9A_RS13205	COG0531	amino acid
AS9A_RS13270	COG1113	amino acid transport
AS9A_RS13285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS9A_RS13340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS9A_RS13345	COG0477	Major facilitator Superfamily
AS9A_RS13350	COG0583	DNA-binding transcription factor activity
AS9A_RS13365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS9A_RS13365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS9A_RS13390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AS9A_RS13395	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS13400	COG2508	Transcriptional regulator
AS9A_RS13400	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AS9A_RS13410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS9A_RS13430	COG0477	Major facilitator Superfamily
AS9A_RS13450	COG1554	hydrolase, family 65, central catalytic
AS9A_RS13490	COG2755	lipolytic protein G-D-S-L family
AS9A_RS13500	COG2197	response regulator
AS9A_RS13505	COG2072	flavoprotein involved in K transport
AS9A_RS13520	COG0633	Ferredoxin
AS9A_RS13555	COG0596	Alpha beta hydrolase
AS9A_RS13565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS9A_RS13610	COG1061	Type III restriction enzyme res subunit
AS9A_RS13640	COG2226	methyltransferase
AS9A_RS13645	COG2197	response regulator
AS9A_RS13750	COG4249	Peptidase C14 caspase catalytic subunit p20
AS9A_RS13750	COG2319	Wd-40 repeat
AS9A_RS13785	COG2124	cytochrome p450
AS9A_RS13805	COG1309	transcriptional regulator
AS9A_RS13810	COG1131	(ABC) transporter
AS9A_RS13840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS9A_RS13880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS9A_RS13885	COG0588	phosphoglycerate mutase activity
AS9A_RS13890	COG1070	Carbohydrate kinase
AS9A_RS13905	COG2814	Major facilitator Superfamily
AS9A_RS13940	COG3012	SEC-C Motif Domain Protein
AS9A_RS14040	COG1793	dna ligase
AS9A_RS14055	COG2124	cytochrome p450
AS9A_RS14115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS9A_RS14120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS9A_RS14145	COG2271	Major facilitator Superfamily
AS9A_RS14170	COG1739	Uncharacterized protein family UPF0029
AS9A_RS14190	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS14200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS9A_RS14205	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS14210	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS14250	COG1074	ATP-dependent DNA helicase activity
AS9A_RS14260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS9A_RS14265	COG0531	amino acid
AS9A_RS14285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS14295	COG4303	Ethanolamine ammonia lyase large subunit
AS9A_RS14300	COG0531	amino acid
AS9A_RS14305	COG1024	Enoyl-CoA hydratase
AS9A_RS14310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS14330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS14355	COG2318	DinB family
AS9A_RS14390	COG4221	oxidoreductase activity
AS9A_RS14405	COG2258	MOSC domain
AS9A_RS14425	COG1115	amino acid carrier protein
AS9A_RS14435	COG0702	epimerase
AS9A_RS14440	COG0488	(ABC) transporter
AS9A_RS14455	COG1027	Aspartate ammonia-lyase
AS9A_RS14465	COG0473	3-isopropylmalate dehydrogenase activity
AS9A_RS14470	COG1012	belongs to the aldehyde dehydrogenase family
AS9A_RS14475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS9A_RS14490	COG0765	amino acid transport
AS9A_RS14495	COG1126	abc transporter atp-binding protein
AS9A_RS14505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS9A_RS14525	COG2186	Transcriptional regulator
AS9A_RS14535	COG1802	Transcriptional regulator
AS9A_RS14540	COG0697	spore germination
AS9A_RS14550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS14560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS9A_RS14565	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS9A_RS14570	COG2132	Multicopper oxidase
AS9A_RS14610	COG2079	MmgE PrpD family protein
AS9A_RS14615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS9A_RS14625	COG2066	Belongs to the glutaminase family
AS9A_RS14635	COG1131	(ABC) transporter
AS9A_RS14640	COG3559	Exporter of polyketide antibiotics
AS9A_RS14650	COG1741	Belongs to the pirin family
AS9A_RS14660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AS9A_RS14665	COG0243	molybdopterin cofactor binding
AS9A_RS14735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS9A_RS14770	COG2226	methyltransferase
AS9A_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS14790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS9A_RS14795	COG1846	Transcriptional regulator
AS9A_RS14800	COG1024	Enoyl-CoA hydratase
AS9A_RS14805	COG0492	ferredoxin-NADP+ reductase activity
AS9A_RS14815	COG2197	response regulator
AS9A_RS14820	COG4585	Histidine kinase
AS9A_RS14850	COG2197	response regulator
AS9A_RS14855	COG4585	Histidine kinase
AS9A_RS14865	COG1131	(ABC) transporter
AS9A_RS14920	COG0505	Belongs to the CarA family
AS9A_RS14950	COG1115	amino acid carrier protein
AS9A_RS14965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS9A_RS14970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AS9A_RS14990	COG1252	NADH dehydrogenase
AS9A_RS15005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS9A_RS15010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS9A_RS15015	COG1120	ATPase activity
AS9A_RS15030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS9A_RS15045	COG1253	flavin adenine dinucleotide binding
AS9A_RS15060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS9A_RS15065	COG1408	metallophosphoesterase
AS9A_RS15090	COG1716	ATPase activity
AS9A_RS15095	COG0509	glycine decarboxylation via glycine cleavage system
AS9A_RS15125	COG1254	Belongs to the acylphosphatase family
AS9A_RS15130	COG0738	Major facilitator superfamily
AS9A_RS15145	COG2072	flavoprotein involved in K transport
AS9A_RS15150	COG3321	synthase
AS9A_RS15150	COG0604	alcohol dehydrogenase
AS9A_RS15170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS9A_RS15175	COG0571	ribonuclease III activity
AS9A_RS15190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AS9A_RS15195	COG0742	ribosomal rna small subunit methyltransferase
AS9A_RS15205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS9A_RS15210	COG1461	Dihydroxyacetone kinase
AS9A_RS15215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS9A_RS15220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS9A_RS15245	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS15280	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS9A_RS15285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AS9A_RS15295	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AS9A_RS15300	COG0494	nUDIX hydrolase
AS9A_RS15300	COG0406	alpha-ribazole phosphatase activity
AS9A_RS15315	COG0066	3-isopropylmalate dehydratase activity
AS9A_RS15320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS9A_RS15340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS9A_RS15345	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS9A_RS15350	COG2271	Major facilitator Superfamily
AS9A_RS15355	COG0473	3-isopropylmalate dehydrogenase activity
AS9A_RS15370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS9A_RS15375	COG0440	acetolactate synthase activity
AS9A_RS15390	COG0129	dihydroxy-acid dehydratase activity
AS9A_RS15410	COG0205	6-phosphofructokinase activity
AS9A_RS15415	COG0471	metal ion transport
AS9A_RS15420	COG3290	protein histidine kinase activity
AS9A_RS15425	COG4565	transcriptional regulatory protein
AS9A_RS15430	COG0154	amidase activity
AS9A_RS15435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS9A_RS15455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS9A_RS15490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS9A_RS15500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS9A_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS15520	COG0110	maltose O-acetyltransferase activity
AS9A_RS15525	COG0686	Belongs to the AlaDH PNT family
AS9A_RS15535	COG2226	methyltransferase
AS9A_RS15545	COG1119	ATPase activity
AS9A_RS15550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS9A_RS15570	COG2409	Drug exporters of the RND superfamily
AS9A_RS15575	COG0183	Belongs to the thiolase family
AS9A_RS15580	COG0346	lactoylglutathione lyase activity
AS9A_RS15595	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AS9A_RS15625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS9A_RS15650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AS9A_RS15655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AS9A_RS15660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS9A_RS15665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AS9A_RS15670	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS9A_RS15675	COG0356	it plays a direct role in the translocation of protons across the membrane
AS9A_RS15690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS9A_RS15700	COG2890	protein-(glutamine-N5) methyltransferase activity
AS9A_RS15710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS9A_RS15715	COG0254	rRNA binding
AS9A_RS15725	COG0083	homoserine kinase activity
AS9A_RS15730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS9A_RS15735	COG0460	homoserine dehydrogenase
AS9A_RS15740	COG0019	diaminopimelate decarboxylase activity
AS9A_RS15745	COG0018	arginyl-trna synthetase
AS9A_RS15800	COG1309	transcriptional regulator
AS9A_RS15815	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS15820	COG1024	Enoyl-CoA hydratase
AS9A_RS15865	COG0523	cobalamin synthesis protein
AS9A_RS15905	COG0438	transferase activity, transferring glycosyl groups
AS9A_RS15935	COG1024	Enoyl-CoA hydratase
AS9A_RS15940	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS15955	COG0435	Glutathione S-transferase
AS9A_RS15960	COG1132	(ABC) transporter
AS9A_RS15965	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS9A_RS15965	COG0567	Dehydrogenase, E1 component
AS9A_RS15995	COG0613	PHP domain protein
AS9A_RS16025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS9A_RS16030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS9A_RS16035	COG5662	AntiSigma factor
AS9A_RS16050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS9A_RS16055	COG2226	methyltransferase
AS9A_RS16060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS9A_RS16065	COG0519	Catalyzes the synthesis of GMP from XMP
AS9A_RS16075	COG0463	Glycosyl transferase, family 2
AS9A_RS16080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS9A_RS16085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS9A_RS16090	COG1611	Belongs to the LOG family
AS9A_RS16095	COG1611	Belongs to the LOG family
AS9A_RS16105	COG2409	Drug exporters of the RND superfamily
AS9A_RS16120	COG1113	amino acid transport
AS9A_RS16125	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS16140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AS9A_RS16145	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AS9A_RS16170	COG0747	negative chemotaxis
AS9A_RS16175	COG1217	gtp-binding protein TYPA
AS9A_RS16185	COG3842	ATPase activity
AS9A_RS16200	COG2154	pterin-4-alpha-carbinolamine dehydratase
AS9A_RS16210	COG0733	neurotransmitter:sodium symporter activity
AS9A_RS16215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS9A_RS16220	COG1051	belongs to the nudix hydrolase family
AS9A_RS16245	COG0012	GTP binding
AS9A_RS16255	COG0628	permease
AS9A_RS16260	COG0419	ATPase involved in DNA repair
AS9A_RS16270	COG1322	Protein conserved in bacteria
AS9A_RS16290	COG1570	exodeoxyribonuclease VII activity
AS9A_RS16295	COG1722	exodeoxyribonuclease VII activity
AS9A_RS16320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS9A_RS16335	COG1072	(Pantothenic acid kinase))
AS9A_RS16355	COG1131	(ABC) transporter
AS9A_RS16360	COG3559	Exporter of polyketide antibiotics
AS9A_RS16365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AS9A_RS16370	COG1331	Highly conserved protein containing a thioredoxin domain
AS9A_RS16380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS9A_RS16390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS9A_RS16410	COG1309	transcriptional regulator
AS9A_RS16415	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS16425	COG1024	Enoyl-CoA hydratase
AS9A_RS16440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS9A_RS16445	COG3383	formate dehydrogenase (NAD+) activity
AS9A_RS16450	COG0277	FAD linked oxidase domain protein
AS9A_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS16465	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS16470	COG0730	response to heat
AS9A_RS16475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS9A_RS16475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS9A_RS16500	COG2755	lipolytic protein G-D-S-L family
AS9A_RS16505	COG0183	Belongs to the thiolase family
AS9A_RS16520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS9A_RS16525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS9A_RS16535	COG1263	PTS System
AS9A_RS16540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS9A_RS16550	COG0667	Aldo Keto reductase
AS9A_RS16555	COG2188	Transcriptional regulator
AS9A_RS16595	COG5290	Psort location Cytoplasmic, score
AS9A_RS16630	COG0148	phosphopyruvate hydratase activity
AS9A_RS16640	COG3956	TIGRFAM MazG family protein
AS9A_RS16650	COG1309	transcriptional regulator
AS9A_RS16675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AS9A_RS16690	COG0193	aminoacyl-tRNA hydrolase activity
AS9A_RS16695	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS16700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AS9A_RS16710	COG3265	gluconokinase activity
AS9A_RS16715	COG2610	gluconate transmembrane transporter activity
AS9A_RS16720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS9A_RS16735	COG2326	polyphosphate kinase activity
AS9A_RS16740	COG0488	(ABC) transporter
AS9A_RS16745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AS9A_RS16750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS9A_RS16755	COG3583	domain protein
AS9A_RS16760	COG0084	hydrolase, TatD family'
AS9A_RS16765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS9A_RS16800	COG1725	Transcriptional regulator
AS9A_RS16805	COG1393	Belongs to the ArsC family
AS9A_RS16810	COG0596	Alpha beta hydrolase
AS9A_RS16815	COG2365	Tyrosine phosphatase family
AS9A_RS16825	COG0659	secondary active sulfate transmembrane transporter activity
AS9A_RS16840	COG1201	RNA secondary structure unwinding
AS9A_RS16845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS9A_RS16895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AS9A_RS16905	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS9A_RS16920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS9A_RS16945	COG1136	(ABC) transporter
AS9A_RS16950	COG2177	Part of the ABC transporter FtsEX involved in
AS9A_RS16960	COG1937	Protein conserved in bacteria
AS9A_RS16965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS9A_RS16975	COG1131	(ABC) transporter
AS9A_RS16980	COG3559	Exporter of polyketide antibiotics
AS9A_RS17010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS9A_RS17020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS9A_RS17025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS9A_RS17055	COG0315	cyclic pyranopterin monophosphate synthase activity
AS9A_RS17055	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS9A_RS17060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS9A_RS17065	COG2205	protein histidine kinase activity
AS9A_RS17070	COG0745	RESPONSE REGULATOR receiver
AS9A_RS17075	COG2860	membrane
AS9A_RS17085	COG0254	rRNA binding
AS9A_RS17105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS9A_RS17110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS9A_RS17115	COG0679	Auxin Efflux Carrier
AS9A_RS17120	COG0138	bifunctional purine biosynthesis protein purh
AS9A_RS17140	COG0045	succinate-CoA ligase (ADP-forming) activity
AS9A_RS17145	COG0739	heme binding
AS9A_RS17165	COG0166	Belongs to the GPI family
AS9A_RS17225	COG0154	amidase activity
AS9A_RS17230	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AS9A_RS17235	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS17250	COG1309	transcriptional regulator
AS9A_RS17260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS9A_RS17285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS9A_RS17300	COG1309	transcriptional regulator
AS9A_RS17325	COG0736	holo-[acyl-carrier-protein] synthase activity
AS9A_RS17355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS9A_RS17370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS9A_RS17380	COG3191	aminopeptidase activity
AS9A_RS17390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AS9A_RS17395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS9A_RS17400	COG1335	isochorismatase
AS9A_RS17425	COG4607	ABC-type enterochelin transport system periplasmic component
AS9A_RS17455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS9A_RS17520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS9A_RS17525	COG1780	Probably involved in ribonucleotide reductase function
AS9A_RS17540	COG1309	transcriptional regulator
AS9A_RS17570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS9A_RS17590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AS9A_RS17600	COG2267	carboxylic ester hydrolase activity
AS9A_RS17635	COG2133	pyrroloquinoline quinone binding
AS9A_RS17640	COG1063	alcohol dehydrogenase
AS9A_RS17650	COG2226	methyltransferase
AS9A_RS17655	COG0366	Alpha amylase catalytic
AS9A_RS17660	COG1609	Transcriptional regulator
AS9A_RS17665	COG1940	carbohydrate kinase activity
AS9A_RS17670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS9A_RS17675	COG0129	dihydroxy-acid dehydratase activity
AS9A_RS17680	COG0837	glucose binding
AS9A_RS17685	COG0800	Aldolase
AS9A_RS17690	COG0697	spore germination
AS9A_RS17735	COG0366	Alpha amylase catalytic
AS9A_RS17785	COG2226	methyltransferase
AS9A_RS17790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS9A_RS17790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS9A_RS17800	COG0438	transferase activity, transferring glycosyl groups
AS9A_RS17830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS9A_RS17840	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AS9A_RS17845	COG2177	Part of the ABC transporter FtsEX involved in
AS9A_RS17850	COG2884	Cell division ATP-binding protein ftsE
AS9A_RS17855	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS9A_RS17860	COG0523	cobalamin synthesis protein
AS9A_RS17865	COG0483	inositol monophosphate 1-phosphatase activity
AS9A_RS17875	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS17885	COG0300	oxidoreductase activity
AS9A_RS17900	COG1615	UPF0182 protein
AS9A_RS17905	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS9A_RS17925	COG0515	serine threonine protein kinase
AS9A_RS17970	COG0210	DNA helicase
AS9A_RS17975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS9A_RS17985	COG0596	Alpha beta hydrolase
AS9A_RS18010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS9A_RS18010	COG2146	nitrite reductase [NAD(P)H] activity
AS9A_RS18015	COG2223	nitrite transmembrane transporter activity
AS9A_RS18020	COG2807	transmembrane transport
AS9A_RS18025	COG2186	Transcriptional regulator
AS9A_RS18045	COG1309	transcriptional regulator
AS9A_RS18060	COG0513	Belongs to the DEAD box helicase family
AS9A_RS18070	COG1192	Involved in chromosome partitioning
AS9A_RS18080	COG1597	lipid kinase activity
AS9A_RS18095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS9A_RS18110	COG2135	peptidase activity
AS9A_RS18115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS9A_RS18120	COG1162	GTPase activity
AS9A_RS18155	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS9A_RS18160	COG1040	competence protein
AS9A_RS18170	COG5002	protein histidine kinase activity
AS9A_RS18210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS9A_RS18215	COG1482	cell wall glycoprotein biosynthetic process
AS9A_RS18225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS9A_RS18245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS9A_RS18250	COG0778	Nitroreductase
AS9A_RS18250	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AS9A_RS18260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS9A_RS18270	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS9A_RS18280	COG1316	TRANSCRIPTIONal
AS9A_RS18295	COG0564	pseudouridine synthase activity
AS9A_RS18305	COG2197	response regulator
AS9A_RS18310	COG4585	Histidine kinase
AS9A_RS18335	COG2205	protein histidine kinase activity
AS9A_RS18340	COG0745	RESPONSE REGULATOR receiver
AS9A_RS18350	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AS9A_RS18350	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AS9A_RS18355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS9A_RS18365	COG0424	maF-like protein
AS9A_RS18385	COG4770	biotin carboxylase activity
AS9A_RS18415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS9A_RS18420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS9A_RS18440	COG3842	ATPase activity
AS9A_RS18455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AS9A_RS18455	COG1473	amidohydrolase
AS9A_RS18460	COG1024	Enoyl-CoA hydratase
AS9A_RS18460	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS9A_RS18465	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS18500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS9A_RS18505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AS9A_RS18515	COG0791	NLP P60 protein
AS9A_RS18515	COG0741	lytic transglycosylase activity
AS9A_RS18540	COG1505	serine-type exopeptidase activity
AS9A_RS18545	COG1414	Transcriptional regulator
AS9A_RS18550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS9A_RS18580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS9A_RS18585	COG0066	3-isopropylmalate dehydratase activity
AS9A_RS18590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AS9A_RS18610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS9A_RS18645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS18650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS9A_RS18675	COG1733	regulation of RNA biosynthetic process
AS9A_RS18690	COG1131	(ABC) transporter
AS9A_RS18695	COG4585	Histidine kinase
AS9A_RS18700	COG2197	response regulator
AS9A_RS18715	COG0431	NADPH-dependent FMN reductase
AS9A_RS18735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS18750	COG2009	succinate dehydrogenase
AS9A_RS18760	COG1053	succinate dehydrogenase
AS9A_RS18765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS9A_RS18795	COG0596	Alpha beta hydrolase
AS9A_RS18795	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS9A_RS18865	COG0778	Nitroreductase
AS9A_RS18875	COG3559	Exporter of polyketide antibiotics
AS9A_RS18880	COG1131	(ABC) transporter
AS9A_RS18885	COG2132	Multicopper oxidase
AS9A_RS18895	COG2375	cellular response to nickel ion
AS9A_RS18925	COG1022	Amp-dependent synthetase and ligase
AS9A_RS18930	COG0559	Belongs to the binding-protein-dependent transport system permease family
AS9A_RS18960	COG2188	Transcriptional regulator
AS9A_RS18965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS9A_RS18975	COG3718	enzyme involved in inositol metabolism
AS9A_RS18980	COG3962	Belongs to the TPP enzyme family
AS9A_RS18985	COG1082	Xylose isomerase domain protein TIM barrel
AS9A_RS18990	COG0673	inositol 2-dehydrogenase activity
AS9A_RS18995	COG1082	Xylose isomerase domain protein TIM barrel
AS9A_RS19005	COG1942	4-Oxalocrotonate Tautomerase
AS9A_RS19010	COG0673	inositol 2-dehydrogenase activity
AS9A_RS19030	COG1686	Belongs to the peptidase S11 family
AS9A_RS19040	COG0180	Tryptophanyl-tRNA synthetase
AS9A_RS19050	COG2814	Major facilitator Superfamily
AS9A_RS19065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS9A_RS19080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS9A_RS19090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS9A_RS19110	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS19115	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS19130	COG0183	Belongs to the thiolase family
AS9A_RS19140	COG1024	Enoyl-CoA hydratase
AS9A_RS19150	COG4989	oxidoreductase activity
AS9A_RS19175	COG0587	DNA-directed DNA polymerase activity
AS9A_RS19180	COG0789	Transcriptional regulator
AS9A_RS19205	COG0515	serine threonine protein kinase
AS9A_RS19210	COG2197	response regulator
AS9A_RS19235	COG0519	Catalyzes the synthesis of GMP from XMP
AS9A_RS19235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS9A_RS19250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS9A_RS19260	COG0516	GMP reductase activity
AS9A_RS19295	COG0459	protein refolding
AS9A_RS19300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS9A_RS19305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS9A_RS19310	COG0456	acetyltransferase
AS9A_RS19365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AS9A_RS19370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AS9A_RS19390	COG1674	ftsk spoiiie
AS9A_RS19400	COG1404	Belongs to the peptidase S8 family
AS9A_RS19495	COG0542	response to heat
AS9A_RS19505	COG0789	Transcriptional regulator
AS9A_RS19510	COG0484	heat shock protein binding
AS9A_RS19515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS9A_RS19520	COG0443	Heat shock 70 kDa protein
AS9A_RS19545	COG0443	Heat shock 70 kDa protein
AS9A_RS19560	COG2181	nitrate reductase activity
AS9A_RS19560	COG0247	lactate metabolic process
AS9A_RS19590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS9A_RS19640	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS19645	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AS9A_RS19655	COG0604	alcohol dehydrogenase
AS9A_RS19665	COG0183	Belongs to the thiolase family
AS9A_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS19675	COG2030	dehydratase
AS9A_RS19680	COG1309	transcriptional regulator
AS9A_RS19685	COG1472	Belongs to the glycosyl hydrolase 3 family
AS9A_RS19700	COG4981	capsule polysaccharide biosynthetic process
AS9A_RS19740	COG0500	methyltransferase
AS9A_RS19755	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AS9A_RS19775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS9A_RS19790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS9A_RS19795	COG1993	acr, cog1993
AS9A_RS19800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS9A_RS19840	COG2267	carboxylic ester hydrolase activity
AS9A_RS19875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS9A_RS19885	COG4134	Bacterial extracellular solute-binding protein
AS9A_RS19900	COG3842	ATPase activity
AS9A_RS19910	COG0019	diaminopimelate decarboxylase activity
AS9A_RS19920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS9A_RS19930	COG2255	four-way junction helicase activity
AS9A_RS19945	COG3590	peptidase
AS9A_RS19955	COG1376	ErfK ybiS ycfS ynhG family protein
AS9A_RS19970	COG0657	acetylesterase activity
AS9A_RS19980	COG1793	dna ligase
AS9A_RS20000	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS9A_RS20010	COG4266	Belongs to the allantoicase family
AS9A_RS20035	COG0640	Transcriptional regulator
AS9A_RS20045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS9A_RS20045	COG2080	2 iron, 2 sulfur cluster binding
AS9A_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS20070	COG0402	S-adenosylhomocysteine deaminase activity
AS9A_RS20100	COG1403	HNH endonuclease
AS9A_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS20125	COG0702	epimerase
AS9A_RS20140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS9A_RS20170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS9A_RS20175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS9A_RS20180	COG1120	ATPase activity
AS9A_RS20185	COG3411	Ferredoxin
AS9A_RS20195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS9A_RS20205	COG1607	acyl-coa hydrolase
AS9A_RS20215	COG3199	ATP-NAD kinase
AS9A_RS20220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS9A_RS20225	COG0022	dehydrogenase e1 component
AS9A_RS20235	COG3284	Transcriptional regulator
AS9A_RS20260	COG2226	methyltransferase
AS9A_RS20280	COG1063	alcohol dehydrogenase
AS9A_RS20290	COG2508	Transcriptional regulator
AS9A_RS20315	COG0154	amidase activity
AS9A_RS20320	COG0439	Biotin carboxylase
AS9A_RS20335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS9A_RS20350	COG2252	PERMEase
AS9A_RS20360	COG0741	lytic transglycosylase activity
AS9A_RS20385	COG2274	protein secretion by the type I secretion system
AS9A_RS20390	COG1132	(ABC) transporter
AS9A_RS20425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS9A_RS20460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS9A_RS20465	COG2161	toxin-antitoxin pair type II binding
AS9A_RS20470	COG4115	mRNA cleavage
AS9A_RS20475	COG2826	transposase and inactivated derivatives, IS30 family
AS9A_RS20485	COG1309	transcriptional regulator
AS9A_RS20525	COG0477	Major facilitator Superfamily
AS9A_RS20575	COG2274	protein secretion by the type I secretion system
AS9A_RS20630	COG1953	Uracil, thiamine, allantoin
AS9A_RS20635	COG1288	antiporter activity
AS9A_RS20640	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS20645	COG2072	flavoprotein involved in K transport
AS9A_RS20650	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS20660	COG1024	Enoyl-CoA hydratase
AS9A_RS20675	COG2197	response regulator
AS9A_RS20680	COG4585	Histidine kinase
AS9A_RS20695	COG0535	radical SAM domain protein
AS9A_RS20790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS9A_RS20800	COG2030	dehydratase
AS9A_RS20805	COG1960	acyl-CoA dehydrogenase activity
AS9A_RS20820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS9A_RS20825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS9A_RS20830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS9A_RS20840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS9A_RS20850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS9A_RS20900	COG0535	radical SAM domain protein
AS9A_RS20910	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS20915	COG0733	neurotransmitter:sodium symporter activity
AS9A_RS20925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS9A_RS20930	COG2376	Dihydroxyacetone kinase
AS9A_RS20935	COG1461	Dihydroxyacetone kinase
AS9A_RS20940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS9A_RS20940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS9A_RS20950	COG4221	oxidoreductase activity
AS9A_RS20980	COG0640	Transcriptional regulator
AS9A_RS20995	COG0702	epimerase
AS9A_RS21000	COG1733	regulation of RNA biosynthetic process
AS9A_RS21005	COG3842	ATPase activity
AS9A_RS21010	COG0395	ABC-type sugar transport system, permease component
AS9A_RS21015	COG1175	transmembrane transport
AS9A_RS21030	COG1063	alcohol dehydrogenase
AS9A_RS21040	COG1070	Carbohydrate kinase
AS9A_RS21080	COG0789	Transcriptional regulator
AS9A_RS21085	COG2197	response regulator
AS9A_RS21090	COG4585	Histidine kinase
AS9A_RS21115	COG1796	DNA polymerase
AS9A_RS21115	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS9A_RS21120	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AS9A_RS21130	COG0517	IMP dehydrogenase activity
AS9A_RS21165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS9A_RS21170	COG0649	NAD binding
AS9A_RS21185	COG1034	ATP synthesis coupled electron transport
AS9A_RS21190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AS9A_RS21195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AS9A_RS21195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS9A_RS21245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS9A_RS21245	COG0475	glutathione-regulated potassium exporter activity
AS9A_RS21250	COG0640	Transcriptional regulator
AS9A_RS21265	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AS9A_RS21295	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS21300	COG1024	Enoyl-CoA hydratase
AS9A_RS21310	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS21370	COG1454	alcohol dehydrogenase
AS9A_RS21375	COG0300	oxidoreductase activity
AS9A_RS21390	COG0300	oxidoreductase activity
AS9A_RS21430	COG3290	protein histidine kinase activity
AS9A_RS21435	COG4565	transcriptional regulatory protein
AS9A_RS21450	COG4221	oxidoreductase activity
AS9A_RS21455	COG0657	acetylesterase activity
AS9A_RS21465	COG0583	DNA-binding transcription factor activity
AS9A_RS21470	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS21480	COG4335	DNA alkylation repair
AS9A_RS21485	COG2508	Transcriptional regulator
AS9A_RS21490	COG0318	PFAM AMP-dependent synthetase and ligase
AS9A_RS21510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS9A_RS21520	COG2066	Belongs to the glutaminase family
AS9A_RS21525	COG1846	Transcriptional regulator
AS9A_RS21535	COG1668	transmembrane transport
AS9A_RS21540	COG4152	abc transporter atp-binding protein
AS9A_RS21555	COG0768	penicillin binding
AS9A_RS21580	COG0640	Transcriptional regulator
AS9A_RS21610	COG0039	L-malate dehydrogenase activity
AS9A_RS21615	COG2050	protein possibly involved in aromatic compounds catabolism
AS9A_RS21620	COG1309	transcriptional regulator
AS9A_RS21635	COG0305	Participates in initiation and elongation during chromosome replication
AS9A_RS21640	COG0359	binds to the 23S rRNA
AS9A_RS21645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS9A_RS21675	COG4585	Histidine kinase
AS9A_RS21695	COG0506	proline dehydrogenase activity
AS9A_RS21710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS9A_RS21755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS9A_RS21800	COG1028	Short-chain dehydrogenase reductase Sdr
AS9A_RS21805	COG0495	leucyl-tRNA aminoacylation
AS9A_RS21815	COG0346	lactoylglutathione lyase activity
AS9A_RS21830	COG1678	Uncharacterized ACR, COG1678
AS9A_RS21840	COG0617	tRNA 3'-terminal CCA addition
AS9A_RS21860	COG1595	DNA-templated transcription, initiation
AS9A_RS21885	COG3409	Peptidoglycan-binding domain 1 protein
AS9A_RS21885	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS9A_RS21900	COG1192	Involved in chromosome partitioning
AS9A_RS21905	COG0357	Ribosomal RNA small subunit methyltransferase G
AS9A_RS21915	COG0706	membrane insertase activity
AS9A_RS22150	COG0768	penicillin binding
AS9A_RS22195	COG0070	glutamate synthase
AS9A_RS22195	COG0067	glutamate synthase
AS9A_RS22195	COG0069	glutamate synthase activity
AS9A_RS22325	COG1131	(ABC) transporter
AS9A_RS22435	COG1216	Glycosyl transferase, family 2
AS9A_RS22650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS9A_RS22655	COG1396	sequence-specific DNA binding
AS9A_RS22710	COG0488	(ABC) transporter
AS9A_RS22725	COG0657	acetylesterase activity
AS9A_RS22730	COG1309	transcriptional regulator
AS9A_RS22785	COG1011	Hydrolase
AS9A_RS22820	COG3835	regulator
AS9A_RS22860	COG2815	serine threonine protein kinase
AS9A_RS22860	COG0515	serine threonine protein kinase
AS9A_RS22890	COG2814	Major facilitator Superfamily
AS9A_RS22935	COG1309	transcriptional regulator