locus-tag	class	description
IPV69_RS00020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IPV69_RS00035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPV69_RS00040	COG0515	serine threonine protein kinase
IPV69_RS00040	COG2815	serine threonine protein kinase
IPV69_RS00055	COG3119	arylsulfatase activity
IPV69_RS00090	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPV69_RS00100	COG1595	DNA-templated transcription, initiation
IPV69_RS00120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS00125	COG1459	type II secretion system
IPV69_RS00170	COG1450	Type ii and iii secretion system protein
IPV69_RS00170	COG1450	Type ii and iii secretion system protein
IPV69_RS00195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPV69_RS00260	COG1872	DUF167
IPV69_RS00265	COG0657	acetylesterase activity
IPV69_RS00265	COG2755	lipolytic protein G-D-S-L family
IPV69_RS00270	COG1063	alcohol dehydrogenase
IPV69_RS00305	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IPV69_RS00320	COG0457	Tetratricopeptide repeat
IPV69_RS00335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IPV69_RS00350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IPV69_RS00370	COG1196	nuclear chromosome segregation
IPV69_RS00385	COG0515	serine threonine protein kinase
IPV69_RS00385	COG2815	serine threonine protein kinase
IPV69_RS00390	COG0823	Involved in the tonB-independent uptake of proteins
IPV69_RS00400	COG0434	BtpA family
IPV69_RS00425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS00480	COG3119	arylsulfatase activity
IPV69_RS00485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPV69_RS00520	COG3385	transposase activity
IPV69_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPV69_RS00540	COG0174	glutamine synthetase
IPV69_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
IPV69_RS00565	COG4191	Histidine kinase
IPV69_RS00580	COG1558	bacterial-type flagellum-dependent cell motility
IPV69_RS00585	COG1677	Flagellar hook-basal body complex protein FliE
IPV69_RS00595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPV69_RS00605	COG1157	protein secretion by the type III secretion system
IPV69_RS00630	COG3385	transposase activity
IPV69_RS00685	COG1595	DNA-templated transcription, initiation
IPV69_RS00700	COG2165	general secretion pathway protein
IPV69_RS00715	COG1741	Belongs to the pirin family
IPV69_RS00725	COG2326	polyphosphate kinase activity
IPV69_RS00740	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS00745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPV69_RS00760	COG2154	pterin-4-alpha-carbinolamine dehydratase
IPV69_RS00775	COG0482	sulfurtransferase activity
IPV69_RS00785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPV69_RS00790	COG0714	Associated with various cellular activities
IPV69_RS00825	COG0505	Belongs to the CarA family
IPV69_RS00835	COG0793	Belongs to the peptidase S41A family
IPV69_RS00840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPV69_RS00850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPV69_RS00880	COG0649	NAD binding
IPV69_RS00890	COG1070	Carbohydrate kinase
IPV69_RS00925	COG0693	protein deglycase activity
IPV69_RS00935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPV69_RS00940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPV69_RS00945	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IPV69_RS00955	COG0473	3-isopropylmalate dehydrogenase activity
IPV69_RS00960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IPV69_RS00980	COG4974	Belongs to the 'phage' integrase family
IPV69_RS00990	COG0322	excinuclease ABC activity
IPV69_RS01005	COG0314	molybdopterin synthase activity
IPV69_RS01015	COG3494	Protein of unknown function (DUF1009)
IPV69_RS01030	COG0367	asparagine synthase
IPV69_RS01055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IPV69_RS01060	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IPV69_RS01065	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IPV69_RS01070	COG2205	protein histidine kinase activity
IPV69_RS01075	COG0745	RESPONSE REGULATOR receiver
IPV69_RS01085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPV69_RS01085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPV69_RS01090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPV69_RS01095	COG0573	inorganic phosphate transmembrane transporter activity
IPV69_RS01120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPV69_RS01130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IPV69_RS01155	COG1139	Iron-sulfur cluster binding protein
IPV69_RS01160	COG1556	Lactate utilization protein
IPV69_RS01190	COG0235	Class ii aldolase
IPV69_RS01225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPV69_RS01230	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IPV69_RS01240	COG4869	propanediol catabolic process
IPV69_RS01250	COG1091	dTDP-4-dehydrorhamnose reductase activity
IPV69_RS01255	COG2346	COG2346, Truncated hemoglobins
IPV69_RS01280	COG1643	Atp-dependent helicase
IPV69_RS01295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IPV69_RS01315	COG0859	PFAM glycosyl transferase family 9
IPV69_RS01320	COG1666	GTP binding
IPV69_RS01325	COG0596	Alpha beta hydrolase
IPV69_RS01335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPV69_RS01335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPV69_RS01365	COG3119	arylsulfatase activity
IPV69_RS01370	COG0598	Magnesium transport protein CorA
IPV69_RS01380	COG0823	Involved in the tonB-independent uptake of proteins
IPV69_RS01400	COG0321	lipoyl(octanoyl) transferase activity
IPV69_RS01420	COG0436	Aminotransferase
IPV69_RS01460	COG2205	protein histidine kinase activity
IPV69_RS01465	COG0745	RESPONSE REGULATOR receiver
IPV69_RS01470	COG0628	permease
IPV69_RS01475	COG0640	Transcriptional regulator
IPV69_RS01500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPV69_RS01515	COG0069	glutamate synthase activity
IPV69_RS01515	COG0070	glutamate synthase
IPV69_RS01515	COG0067	glutamate synthase
IPV69_RS01555	COG1899	peptidyl-lysine modification to peptidyl-hypusine
IPV69_RS01560	COG1573	uracil-dna glycosylase
IPV69_RS01565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPV69_RS01570	COG1562	ergosterol biosynthetic process
IPV69_RS01580	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IPV69_RS01600	COG2234	aminopeptidase activity
IPV69_RS01610	COG0784	Response regulator, receiver
IPV69_RS01615	COG4251	negative regulation of phosphorylation
IPV69_RS01620	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPV69_RS01635	COG2815	serine threonine protein kinase
IPV69_RS01635	COG0515	serine threonine protein kinase
IPV69_RS01725	COG1459	type II secretion system
IPV69_RS01735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS01760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IPV69_RS01775	COG0473	3-isopropylmalate dehydrogenase activity
IPV69_RS01780	COG0492	ferredoxin-NADP+ reductase activity
IPV69_RS01785	COG0594	ribonuclease P activity
IPV69_RS01790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IPV69_RS01800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IPV69_RS01810	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IPV69_RS01855	COG0673	inositol 2-dehydrogenase activity
IPV69_RS01865	COG1477	protein flavinylation
IPV69_RS01870	COG0673	inositol 2-dehydrogenase activity
IPV69_RS01890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPV69_RS01895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPV69_RS01900	COG0052	Belongs to the universal ribosomal protein uS2 family
IPV69_RS01920	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IPV69_RS01935	COG0251	oxidation-reduction process
IPV69_RS01960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPV69_RS01980	COG0835	chemotaxis
IPV69_RS01980	COG0784	Response regulator, receiver
IPV69_RS01985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IPV69_RS01995	COG3394	polysaccharide catabolic process
IPV69_RS02020	COG0463	Glycosyl transferase, family 2
IPV69_RS02030	COG1132	(ABC) transporter
IPV69_RS02035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPV69_RS02040	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS02050	COG2165	general secretion pathway protein
IPV69_RS02085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IPV69_RS02105	COG0542	response to heat
IPV69_RS02175	COG0513	Belongs to the DEAD box helicase family
IPV69_RS02195	COG0494	nUDIX hydrolase
IPV69_RS02205	COG1331	Highly conserved protein containing a thioredoxin domain
IPV69_RS02220	COG1007	ATP synthesis coupled electron transport
IPV69_RS02230	COG3119	arylsulfatase activity
IPV69_RS02265	COG0156	8-amino-7-oxononanoate synthase activity
IPV69_RS02270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPV69_RS02295	COG0657	acetylesterase activity
IPV69_RS02310	COG2815	serine threonine protein kinase
IPV69_RS02310	COG0515	serine threonine protein kinase
IPV69_RS02365	COG0745	RESPONSE REGULATOR receiver
IPV69_RS02370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IPV69_RS02370	COG2199	diguanylate cyclase activity
IPV69_RS02380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPV69_RS02385	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPV69_RS02390	COG0671	phosphoesterase, PA-phosphatase related
IPV69_RS02400	COG2755	lipolytic protein G-D-S-L family
IPV69_RS02415	COG2226	methyltransferase
IPV69_RS02420	COG0363	glucosamine-6-phosphate deaminase activity
IPV69_RS02455	COG0222	ribosome binding
IPV69_RS02460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IPV69_RS02480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IPV69_RS02485	COG2271	Major facilitator Superfamily
IPV69_RS02495	COG0148	phosphopyruvate hydratase activity
IPV69_RS02510	COG1214	PFAM Peptidase M22, glycoprotease
IPV69_RS02520	COG1516	flagellar protein fliS
IPV69_RS02535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IPV69_RS02540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPV69_RS02575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPV69_RS02585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPV69_RS02610	COG0688	phosphatidylethanolamine metabolic process
IPV69_RS02615	COG1183	phosphatidylcholine synthase activity
IPV69_RS02695	COG0237	dephospho-CoA kinase activity
IPV69_RS02700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPV69_RS02710	COG0133	tryptophan synthase activity
IPV69_RS02725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPV69_RS02730	COG0004	ammonium transporteR
IPV69_RS02770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IPV69_RS02795	COG0742	ribosomal rna small subunit methyltransferase
IPV69_RS02800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IPV69_RS02825	COG1187	pseudouridine synthase activity
IPV69_RS02850	COG0823	Involved in the tonB-independent uptake of proteins
IPV69_RS02850	COG1506	peptidase
IPV69_RS02850	COG4946	Tricorn protease homolog
IPV69_RS02880	COG3119	arylsulfatase activity
IPV69_RS02910	COG1309	transcriptional regulator
IPV69_RS02935	COG0681	Belongs to the peptidase S26 family
IPV69_RS02940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPV69_RS02960	COG0667	Aldo Keto reductase
IPV69_RS02970	COG3046	protein related to deoxyribodipyrimidine photolyase
IPV69_RS03015	COG0542	response to heat
IPV69_RS03030	COG0006	proline dipeptidase activity
IPV69_RS03035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPV69_RS03040	COG0514	ATP-dependent DNA helicase (RecQ)
IPV69_RS03045	COG1063	alcohol dehydrogenase
IPV69_RS03065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPV69_RS03070	COG0581	inorganic phosphate transmembrane transporter activity
IPV69_RS03075	COG0573	inorganic phosphate transmembrane transporter activity
IPV69_RS03080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IPV69_RS03090	COG3119	arylsulfatase activity
IPV69_RS03140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IPV69_RS03195	COG1381	Involved in DNA repair and RecF pathway recombination
IPV69_RS03225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IPV69_RS03230	COG0497	DNA recombination
IPV69_RS03235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPV69_RS03235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPV69_RS03240	COG3119	arylsulfatase activity
IPV69_RS03245	COG3119	arylsulfatase activity
IPV69_RS03270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPV69_RS03305	COG1858	cytochrome C peroxidase
IPV69_RS03320	COG0326	Molecular chaperone. Has ATPase activity
IPV69_RS03330	COG1515	deoxyribonuclease V activity
IPV69_RS03340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPV69_RS03370	COG0159	tryptophan synthase activity
IPV69_RS03405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPV69_RS03420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPV69_RS03430	COG0673	inositol 2-dehydrogenase activity
IPV69_RS03435	COG2967	ApaG domain
IPV69_RS03440	COG3842	ATPase activity
IPV69_RS03445	COG1840	ABC-type Fe3 transport system, periplasmic component
IPV69_RS03485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPV69_RS03500	COG2226	methyltransferase
IPV69_RS03535	COG0352	thiamine-phosphate diphosphorylase activity
IPV69_RS03545	COG0129	dihydroxy-acid dehydratase activity
IPV69_RS03595	COG4191	Histidine kinase
IPV69_RS03600	COG2204	response regulator
IPV69_RS03625	COG1573	uracil-dna glycosylase
IPV69_RS03635	COG3132	Protein of unknown function, DUF480
IPV69_RS03650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPV69_RS03660	COG1162	GTPase activity
IPV69_RS03670	COG0463	Glycosyl transferase, family 2
IPV69_RS03675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPV69_RS03690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IPV69_RS03710	COG1136	(ABC) transporter
IPV69_RS03750	COG0765	amino acid transport
IPV69_RS03755	COG1126	abc transporter atp-binding protein
IPV69_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS03780	COG0673	inositol 2-dehydrogenase activity
IPV69_RS03785	COG3609	addiction module antidote protein, CC2985 family
IPV69_RS03845	COG0167	dihydroorotate dehydrogenase activity
IPV69_RS03850	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPV69_RS03855	COG1129	ABC transporter
IPV69_RS03905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPV69_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS03935	COG4821	SIS domain
IPV69_RS03945	COG2255	four-way junction helicase activity
IPV69_RS03965	COG0525	valine-tRNA ligase activity
IPV69_RS03980	COG0564	pseudouridine synthase activity
IPV69_RS04010	COG0612	Peptidase, M16
IPV69_RS04025	COG0632	four-way junction helicase activity
IPV69_RS04040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPV69_RS04050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPV69_RS04075	COG0784	Response regulator, receiver
IPV69_RS04075	COG2205	protein histidine kinase activity
IPV69_RS04085	COG0544	peptidyl-prolyl cis-trans isomerase activity
IPV69_RS04090	COG0124	histidyl-tRNA synthetase
IPV69_RS04140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS04165	COG0644	oxidoreductase
IPV69_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS04235	COG3119	arylsulfatase activity
IPV69_RS04240	COG3119	arylsulfatase activity
IPV69_RS04245	COG3119	arylsulfatase activity
IPV69_RS04305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IPV69_RS04340	COG1191	sigma factor activity
IPV69_RS04365	COG1082	Xylose isomerase domain protein TIM barrel
IPV69_RS04370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPV69_RS04385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPV69_RS04400	COG3119	arylsulfatase activity
IPV69_RS04400	COG3408	Glycogen debranching enzyme
IPV69_RS04420	COG1192	Involved in chromosome partitioning
IPV69_RS04470	COG0489	protein tyrosine kinase activity
IPV69_RS04485	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS04500	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS04505	COG0297	glycogen (starch) synthase activity
IPV69_RS04530	COG0297	glycogen (starch) synthase activity
IPV69_RS04590	COG0275	rRNA processing
IPV69_RS04595	COG2226	methyltransferase
IPV69_RS04600	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS04610	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS04635	COG1609	Transcriptional regulator
IPV69_RS04635	COG2207	Transcriptional regulator
IPV69_RS04655	COG3177	Filamentation induced by cAMP protein fic
IPV69_RS04690	COG3311	Transcriptional regulator
IPV69_RS04745	COG5001	Diguanylate cyclase
IPV69_RS04780	COG3335	DDE superfamily endonuclease
IPV69_RS04790	COG0358	DNA primase activity
IPV69_RS04795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPV69_RS04800	COG0657	acetylesterase activity
IPV69_RS04830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPV69_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS04905	COG1657	PFAM Prenyltransferase squalene oxidase
IPV69_RS04910	COG1233	COG1233 Phytoene dehydrogenase and related
IPV69_RS04920	COG1562	ergosterol biosynthetic process
IPV69_RS04940	COG1132	(ABC) transporter
IPV69_RS04955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPV69_RS04960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPV69_RS04970	COG0575	Belongs to the CDS family
IPV69_RS04975	COG0784	Response regulator, receiver
IPV69_RS04975	COG2205	protein histidine kinase activity
IPV69_RS04980	COG0784	Response regulator, receiver
IPV69_RS04985	COG4251	negative regulation of phosphorylation
IPV69_RS04995	COG1970	mechanosensitive ion channel activity
IPV69_RS04995	COG1970	mechanosensitive ion channel activity
IPV69_RS05005	COG1702	phosphate starvation-inducible protein PhoH
IPV69_RS05010	COG1480	7TM receptor with intracellular HD hydrolase
IPV69_RS05020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IPV69_RS05035	COG3119	arylsulfatase activity
IPV69_RS05075	COG0017	Asparaginyl-tRNA synthetase
IPV69_RS05085	COG0175	sulfate reduction
IPV69_RS05090	COG2895	sulfate adenylyltransferase (ATP) activity
IPV69_RS05090	COG0529	Catalyzes the synthesis of activated sulfate
IPV69_RS05100	COG0564	pseudouridine synthase activity
IPV69_RS05110	COG0463	Glycosyl transferase, family 2
IPV69_RS05120	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IPV69_RS05140	COG1596	polysaccharide export
IPV69_RS05150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPV69_RS05210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPV69_RS05220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPV69_RS05225	COG0839	Belongs to the complex I subunit 6 family
IPV69_RS05260	COG4806	L-rhamnose isomerase
IPV69_RS05265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPV69_RS05285	COG0009	L-threonylcarbamoyladenylate synthase
IPV69_RS05295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPV69_RS05300	COG0657	acetylesterase activity
IPV69_RS05325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IPV69_RS05335	COG0306	phosphate transporter
IPV69_RS05340	COG2135	peptidase activity
IPV69_RS05350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPV69_RS05360	COG2165	general secretion pathway protein
IPV69_RS05370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS05375	COG2755	lipolytic protein G-D-S-L family
IPV69_RS05380	COG3119	arylsulfatase activity
IPV69_RS05385	COG3119	arylsulfatase activity
IPV69_RS05410	COG0673	inositol 2-dehydrogenase activity
IPV69_RS05420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPV69_RS05425	COG0704	Plays a role in the regulation of phosphate uptake
IPV69_RS05450	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS05460	COG2226	methyltransferase
IPV69_RS05465	COG0363	glucosamine-6-phosphate deaminase activity
IPV69_RS05480	COG3119	arylsulfatase activity
IPV69_RS05490	COG3119	arylsulfatase activity
IPV69_RS05510	COG4251	negative regulation of phosphorylation
IPV69_RS05520	COG2165	general secretion pathway protein
IPV69_RS05530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPV69_RS05540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IPV69_RS05550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPV69_RS05560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPV69_RS05560	COG3170	Tfp pilus assembly protein FimV
IPV69_RS05565	COG0195	Participates in both transcription termination and antitermination
IPV69_RS05570	COG3842	ATPase activity
IPV69_RS05575	COG2267	carboxylic ester hydrolase activity
IPV69_RS05585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPV69_RS05590	COG0443	Heat shock 70 kDa protein
IPV69_RS05600	COG1959	2 iron, 2 sulfur cluster binding
IPV69_RS05605	COG4770	biotin carboxylase activity
IPV69_RS05610	COG3665	Urea carboxylase-associated protein
IPV69_RS05615	COG3665	Urea carboxylase-associated protein
IPV69_RS05645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPV69_RS05655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPV69_RS05670	COG0612	Peptidase, M16
IPV69_RS05675	COG0612	Peptidase, M16
IPV69_RS05715	COG0673	inositol 2-dehydrogenase activity
IPV69_RS05720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IPV69_RS05725	COG0196	riboflavin kinase activity
IPV69_RS05735	COG1506	peptidase
IPV69_RS05735	COG0823	Involved in the tonB-independent uptake of proteins
IPV69_RS05760	COG0516	GMP reductase activity
IPV69_RS05760	COG0517	IMP dehydrogenase activity
IPV69_RS05770	COG0516	GMP reductase activity
IPV69_RS05770	COG0517	IMP dehydrogenase activity
IPV69_RS05790	COG0129	dihydroxy-acid dehydratase activity
IPV69_RS05820	COG4566	intracellular signal transduction
IPV69_RS05825	COG0210	DNA helicase
IPV69_RS05830	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IPV69_RS05835	COG0589	response to stress
IPV69_RS06060	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IPV69_RS06065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPV69_RS06070	COG3119	arylsulfatase activity
IPV69_RS06115	COG1175	transmembrane transport
IPV69_RS06120	COG0395	ABC-type sugar transport system, permease component
IPV69_RS06165	COG2165	general secretion pathway protein
IPV69_RS06170	COG3119	arylsulfatase activity
IPV69_RS06320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IPV69_RS06375	COG1459	type II secretion system
IPV69_RS06380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS06410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPV69_RS06415	COG3938	Belongs to the proline racemase family
IPV69_RS06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IPV69_RS06425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPV69_RS06430	COG2045	Belongs to the ComB family
IPV69_RS06435	COG2204	response regulator
IPV69_RS06440	COG2205	protein histidine kinase activity
IPV69_RS06440	COG2202	Pas domain
IPV69_RS06445	COG3119	arylsulfatase activity
IPV69_RS06460	COG1595	DNA-templated transcription, initiation
IPV69_RS06465	COG1217	gtp-binding protein TYPA
IPV69_RS06470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IPV69_RS06475	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS06480	COG1560	Kdo2-lipid A biosynthetic process
IPV69_RS06485	COG4260	virion core protein, lumpy skin disease virus
IPV69_RS06500	COG3119	arylsulfatase activity
IPV69_RS06500	COG3408	Glycogen debranching enzyme
IPV69_RS06525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPV69_RS06530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPV69_RS06535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IPV69_RS06550	COG0443	Heat shock 70 kDa protein
IPV69_RS06565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IPV69_RS06570	COG1253	flavin adenine dinucleotide binding
IPV69_RS06600	COG5183	chlorophyll binding
IPV69_RS06600	COG2133	pyrroloquinoline quinone binding
IPV69_RS06615	COG2165	general secretion pathway protein
IPV69_RS06620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IPV69_RS06655	COG0402	S-adenosylhomocysteine deaminase activity
IPV69_RS06660	COG0363	glucosamine-6-phosphate deaminase activity
IPV69_RS06670	COG0745	RESPONSE REGULATOR receiver
IPV69_RS06680	COG2201	protein-glutamate methylesterase activity
IPV69_RS06690	COG2197	response regulator
IPV69_RS06695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IPV69_RS06705	COG0840	transmembrane signaling receptor activity
IPV69_RS06710	COG0835	chemotaxis
IPV69_RS06715	COG2198	Histidine kinase
IPV69_RS06715	COG0643	Histidine kinase
IPV69_RS06725	COG3386	PFAM SMP-30 Gluconolaconase
IPV69_RS06730	COG2208	phosphoserine phosphatase activity
IPV69_RS06735	COG0717	Belongs to the dCTP deaminase family
IPV69_RS06740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPV69_RS06800	COG2207	Transcriptional regulator
IPV69_RS06800	COG1609	Transcriptional regulator
IPV69_RS06925	COG3422	double-strand break repair
IPV69_RS06930	COG3119	arylsulfatase activity
IPV69_RS06945	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPV69_RS06950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPV69_RS06960	COG0110	maltose O-acetyltransferase activity
IPV69_RS06970	COG3001	Fructosamine kinase
IPV69_RS06985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IPV69_RS07005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPV69_RS07015	COG1032	radical SAM domain protein
IPV69_RS07020	COG1136	(ABC) transporter
IPV69_RS07025	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS07055	COG0602	queuosine metabolic process
IPV69_RS07060	COG0673	inositol 2-dehydrogenase activity
IPV69_RS07100	COG3119	arylsulfatase activity
IPV69_RS07115	COG0557	exoribonuclease II activity
IPV69_RS07125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPV69_RS07130	COG1397	ADP-ribosylglycohydrolase
IPV69_RS07135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IPV69_RS07160	COG0484	heat shock protein binding
IPV69_RS07170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPV69_RS07175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPV69_RS07220	COG0667	Aldo Keto reductase
IPV69_RS07230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPV69_RS07235	COG0251	oxidation-reduction process
IPV69_RS07255	COG1643	Atp-dependent helicase
IPV69_RS07300	COG2095	MarC family integral membrane protein
IPV69_RS07305	COG1012	belongs to the aldehyde dehydrogenase family
IPV69_RS07330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IPV69_RS07335	COG1450	Type ii and iii secretion system protein
IPV69_RS07365	COG0489	protein tyrosine kinase activity
IPV69_RS07365	COG3206	protein involved in exopolysaccharide biosynthesis
IPV69_RS07370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IPV69_RS07405	COG3119	arylsulfatase activity
IPV69_RS07425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPV69_RS07430	COG0706	membrane insertase activity
IPV69_RS07440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPV69_RS07465	COG1505	serine-type exopeptidase activity
IPV69_RS07485	COG1546	Belongs to the CinA family
IPV69_RS07485	COG1058	Belongs to the CinA family
IPV69_RS07505	COG1793	dna ligase
IPV69_RS07520	COG0489	protein tyrosine kinase activity
IPV69_RS07525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPV69_RS07560	COG0714	Associated with various cellular activities
IPV69_RS07655	COG3119	arylsulfatase activity
IPV69_RS07675	COG1595	DNA-templated transcription, initiation
IPV69_RS07680	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS07705	COG0640	Transcriptional regulator
IPV69_RS07710	COG1082	Xylose isomerase domain protein TIM barrel
IPV69_RS07730	COG1881	PFAM PEBP family protein
IPV69_RS07735	COG3119	arylsulfatase activity
IPV69_RS07745	COG3119	arylsulfatase activity
IPV69_RS07750	COG3119	arylsulfatase activity
IPV69_RS07755	COG3119	arylsulfatase activity
IPV69_RS07770	COG4948	Mandelate Racemase Muconate Lactonizing
IPV69_RS07785	COG2719	SpoVR family
IPV69_RS07800	COG2718	Belongs to the UPF0229 family
IPV69_RS07815	COG2766	serine protein kinase
IPV69_RS07820	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IPV69_RS07825	COG1305	Transglutaminase-like
IPV69_RS07860	COG1192	Involved in chromosome partitioning
IPV69_RS07910	COG2373	Large extracellular alpha-helical protein
IPV69_RS07935	COG0826	peptidase U32
IPV69_RS07940	COG1331	Highly conserved protein containing a thioredoxin domain
IPV69_RS07965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPV69_RS07970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IPV69_RS07975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IPV69_RS08000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS08030	COG2010	Cytochrome c
IPV69_RS08040	COG1595	DNA-templated transcription, initiation
IPV69_RS08070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IPV69_RS08070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IPV69_RS08085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPV69_RS08105	COG0776	regulation of translation
IPV69_RS08115	COG1830	Aldolase
IPV69_RS08155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IPV69_RS08170	COG0109	protoheme IX farnesyltransferase activity
IPV69_RS08195	COG1131	(ABC) transporter
IPV69_RS08230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IPV69_RS08240	COG3119	arylsulfatase activity
IPV69_RS08245	COG3119	arylsulfatase activity
IPV69_RS08250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IPV69_RS08260	COG2133	pyrroloquinoline quinone binding
IPV69_RS08260	COG5183	chlorophyll binding
IPV69_RS08270	COG3119	arylsulfatase activity
IPV69_RS08290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPV69_RS08310	COG5002	protein histidine kinase activity
IPV69_RS08335	COG1929	Belongs to the glycerate kinase type-1 family
IPV69_RS08340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IPV69_RS08345	COG1127	ABC transporter
IPV69_RS08380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPV69_RS08390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPV69_RS08395	COG0494	nUDIX hydrolase
IPV69_RS08400	COG4636	protein conserved in cyanobacteria
IPV69_RS08405	COG3876	Protein conserved in bacteria
IPV69_RS08410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPV69_RS08435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPV69_RS08445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPV69_RS08455	COG1530	ribonuclease E activity
IPV69_RS08470	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS08485	COG1082	Xylose isomerase domain protein TIM barrel
IPV69_RS08490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPV69_RS08500	COG2706	6-phosphogluconolactonase activity
IPV69_RS08540	COG2062	phosphohistidine phosphatase, SixA
IPV69_RS08545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IPV69_RS08590	COG2165	general secretion pathway protein
IPV69_RS08595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IPV69_RS08605	COG1074	ATP-dependent DNA helicase activity
IPV69_RS08615	COG0585	pseudouridine synthase activity
IPV69_RS08620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IPV69_RS08625	COG2151	metal-sulfur cluster biosynthetic enzyme
IPV69_RS08630	COG3119	arylsulfatase activity
IPV69_RS08640	COG1216	Glycosyl transferase, family 2
IPV69_RS08645	COG1216	Glycosyl transferase, family 2
IPV69_RS08645	COG0463	Glycosyl transferase, family 2
IPV69_RS08655	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS08715	COG0456	acetyltransferase
IPV69_RS08740	COG2308	Evidence 4 Homologs of previously reported genes of
IPV69_RS08775	COG0436	Aminotransferase
IPV69_RS08790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IPV69_RS08805	COG0287	Prephenate dehydrogenase
IPV69_RS08810	COG0825	malonyl-CoA metabolic process
IPV69_RS08820	COG3119	arylsulfatase activity
IPV69_RS08835	COG1030	water channel activity
IPV69_RS08840	COG1030	water channel activity
IPV69_RS08845	COG4864	UPF0365 protein
IPV69_RS08875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPV69_RS08880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IPV69_RS08940	COG0714	Associated with various cellular activities
IPV69_RS08985	COG0726	polysaccharide deacetylase
IPV69_RS08990	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS09025	COG5002	protein histidine kinase activity
IPV69_RS09025	COG2205	protein histidine kinase activity
IPV69_RS09025	COG0784	Response regulator, receiver
IPV69_RS09030	COG3437	response regulator, receiver
IPV69_RS09040	COG0657	acetylesterase activity
IPV69_RS09055	COG2824	Alkylphosphonate utilization operon protein PhnA
IPV69_RS09070	COG4974	Belongs to the 'phage' integrase family
IPV69_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS09105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IPV69_RS09105	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IPV69_RS09150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPV69_RS09155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPV69_RS09180	COG4948	Mandelate Racemase Muconate Lactonizing
IPV69_RS09185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPV69_RS09230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPV69_RS09250	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IPV69_RS09295	COG2770	Histidine kinase
IPV69_RS09295	COG3437	response regulator, receiver
IPV69_RS09300	COG1706	bacterial-type flagellum-dependent cell motility
IPV69_RS09305	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IPV69_RS09315	COG4786	Flagellar basal body rod
IPV69_RS09320	COG4786	Flagellar basal body rod
IPV69_RS09330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPV69_RS09360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IPV69_RS09375	COG0437	4 iron, 4 sulfur cluster binding
IPV69_RS09410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IPV69_RS09415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPV69_RS09420	COG1845	cytochrome c oxidase, subunit III
IPV69_RS09440	COG0488	(ABC) transporter
IPV69_RS09445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPV69_RS09470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IPV69_RS09490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IPV69_RS09575	COG0440	acetolactate synthase activity
IPV69_RS09580	COG0501	Belongs to the peptidase M48B family
IPV69_RS09605	COG3119	arylsulfatase activity
IPV69_RS09610	COG1132	(ABC) transporter
IPV69_RS09625	COG0138	bifunctional purine biosynthesis protein purh
IPV69_RS09680	COG2009	succinate dehydrogenase
IPV69_RS09695	COG1053	succinate dehydrogenase
IPV69_RS09700	COG0038	chloride channel
IPV69_RS09705	COG1191	sigma factor activity
IPV69_RS09720	COG1419	protein localization to endoplasmic reticulum
IPV69_RS09725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPV69_RS09730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPV69_RS09735	COG1684	flagellar biosynthetic protein fliR
IPV69_RS09745	COG1338	Plays a role in the flagellum-specific transport system
IPV69_RS09755	COG1776	CheC inhibitor of MCP methylation
IPV69_RS09755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPV69_RS09800	COG1674	ftsk spoiiie
IPV69_RS09815	COG1012	belongs to the aldehyde dehydrogenase family
IPV69_RS09845	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPV69_RS09850	COG1129	ABC transporter
IPV69_RS09885	COG0745	RESPONSE REGULATOR receiver
IPV69_RS09895	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPV69_RS09905	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPV69_RS09910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IPV69_RS09930	COG1595	DNA-templated transcription, initiation
IPV69_RS09945	COG0574	Belongs to the PEP-utilizing enzyme family
IPV69_RS09945	COG3848	Pyruvate phosphate dikinase
IPV69_RS10000	COG0123	including yeast histone deacetylase and acetoin utilization protein
IPV69_RS10005	COG0745	RESPONSE REGULATOR receiver
IPV69_RS10015	COG0228	four-way junction DNA binding
IPV69_RS10020	COG0336	Belongs to the RNA methyltransferase TrmD family
IPV69_RS10025	COG0335	large ribosomal subunit rRNA binding
IPV69_RS10030	COG0792	nuclease activity
IPV69_RS10035	COG0084	hydrolase, TatD family'
IPV69_RS10055	COG0423	glycine-tRNA ligase activity
IPV69_RS10060	COG0268	Binds directly to 16S ribosomal RNA
IPV69_RS10070	COG0242	peptide deformylase activity
IPV69_RS10075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPV69_RS10160	COG0372	Belongs to the citrate synthase family
IPV69_RS10195	COG4303	Ethanolamine ammonia lyase large subunit
IPV69_RS10200	COG4302	ethanolamine ammonia-lyase activity
IPV69_RS10220	COG2957	Belongs to the agmatine deiminase family
IPV69_RS10225	COG1166	arginine decarboxylase activity
IPV69_RS10250	COG3693	PFAM glycoside hydrolase, family 10
IPV69_RS10250	COG2382	esterase
IPV69_RS10250	COG3507	Belongs to the glycosyl hydrolase 43 family
IPV69_RS10255	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPV69_RS10260	COG1136	(ABC) transporter
IPV69_RS10270	COG2814	Major facilitator Superfamily
IPV69_RS10300	COG0571	ribonuclease III activity
IPV69_RS10305	COG0745	RESPONSE REGULATOR receiver
IPV69_RS10315	COG0459	protein refolding
IPV69_RS10330	COG1477	protein flavinylation
IPV69_RS10340	COG0437	4 iron, 4 sulfur cluster binding
IPV69_RS10345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPV69_RS10355	COG0837	glucose binding
IPV69_RS10365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPV69_RS10370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IPV69_RS10380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IPV69_RS10385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IPV69_RS10390	COG0859	PFAM glycosyl transferase family 9
IPV69_RS10420	COG0343	queuine tRNA-ribosyltransferase activity
IPV69_RS10425	COG1862	Preprotein translocase
IPV69_RS10440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IPV69_RS10445	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IPV69_RS10470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPV69_RS10480	COG0113	porphobilinogen synthase activity
IPV69_RS10485	COG2205	protein histidine kinase activity
IPV69_RS10485	COG0784	Response regulator, receiver
IPV69_RS10495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPV69_RS10500	COG0667	Aldo Keto reductase
IPV69_RS10510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPV69_RS10540	COG1192	Involved in chromosome partitioning
IPV69_RS10570	COG2706	6-phosphogluconolactonase activity
IPV69_RS10580	COG1639	'signal transduction protein
IPV69_RS10585	COG3685	Protein conserved in bacteria
IPV69_RS10590	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IPV69_RS10595	COG3852	Histidine kinase
IPV69_RS10605	COG0745	RESPONSE REGULATOR receiver
IPV69_RS10640	COG0583	DNA-binding transcription factor activity
IPV69_RS10670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS10710	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPV69_RS10730	COG1073	alpha beta
IPV69_RS10790	COG0772	Belongs to the SEDS family
IPV69_RS10825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IPV69_RS10830	COG4968	Prepilin-type N-terminal cleavage methylation domain
IPV69_RS10835	COG0443	Heat shock 70 kDa protein
IPV69_RS10860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IPV69_RS10875	COG1131	(ABC) transporter
IPV69_RS10880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IPV69_RS10975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IPV69_RS10990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS10995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IPV69_RS11000	COG2814	Major facilitator Superfamily
IPV69_RS11025	COG1132	(ABC) transporter
IPV69_RS11055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPV69_RS11080	COG0037	tRNA processing
IPV69_RS11125	COG1570	exodeoxyribonuclease VII activity
IPV69_RS11175	COG1047	Peptidyl-prolyl cis-trans
IPV69_RS11190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPV69_RS11195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPV69_RS11205	COG0768	penicillin binding
IPV69_RS11230	COG0515	serine threonine protein kinase
IPV69_RS11230	COG2815	serine threonine protein kinase
IPV69_RS11240	COG0811	peptide transport
IPV69_RS11265	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IPV69_RS11275	COG3584	3D domain protein
IPV69_RS11300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPV69_RS11305	COG0673	inositol 2-dehydrogenase activity
IPV69_RS11310	COG1678	Uncharacterized ACR, COG1678
IPV69_RS11335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IPV69_RS11345	COG0126	phosphoglycerate kinase activity
IPV69_RS11350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IPV69_RS11410	COG3119	arylsulfatase activity
IPV69_RS11415	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IPV69_RS11420	COG3119	arylsulfatase activity
IPV69_RS11430	COG0804	urea catabolic process
IPV69_RS11435	COG0832	Belongs to the urease beta subunit family
IPV69_RS11435	COG0831	urea catabolic process
IPV69_RS11440	COG0829	nickel cation binding
IPV69_RS11490	COG0830	nickel cation binding
IPV69_RS11495	COG0375	protein maturation
IPV69_RS11500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPV69_RS11525	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS11540	COG0049	tRNA binding
IPV69_RS11545	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPV69_RS11555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPV69_RS11575	COG2204	response regulator
IPV69_RS11590	COG2096	Adenosyltransferase
IPV69_RS11610	COG5002	protein histidine kinase activity
IPV69_RS11615	COG0784	Response regulator, receiver
IPV69_RS11615	COG2198	Histidine kinase
IPV69_RS11615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPV69_RS11615	COG2205	protein histidine kinase activity
IPV69_RS11620	COG0047	phosphoribosylformylglycinamidine synthase activity
IPV69_RS11650	COG0277	FAD linked oxidase domain protein
IPV69_RS11655	COG3250	beta-galactosidase activity
IPV69_RS11690	COG1137	ATPase activity
IPV69_RS11695	COG1278	Cold shock
IPV69_RS11700	COG1819	glycosyl
IPV69_RS11705	COG1064	alcohol dehydrogenase
IPV69_RS11745	COG0464	growth
IPV69_RS11760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IPV69_RS11770	COG2755	lipolytic protein G-D-S-L family
IPV69_RS11770	COG0657	acetylesterase activity
IPV69_RS11795	COG0318	PFAM AMP-dependent synthetase and ligase
IPV69_RS11840	COG1459	type II secretion system
IPV69_RS11875	COG5401	PFAM Sporulation and spore germination
IPV69_RS11880	COG3119	arylsulfatase activity
IPV69_RS11890	COG2755	lipolytic protein G-D-S-L family
IPV69_RS11890	COG0657	acetylesterase activity
IPV69_RS11895	COG0405	Gamma-glutamyltransferase
IPV69_RS11905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPV69_RS11915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS11920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IPV69_RS11925	COG4537	Required for transformation and DNA binding
IPV69_RS11935	COG1136	(ABC) transporter
IPV69_RS11935	COG0577	efflux transmembrane transporter activity
IPV69_RS11950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPV69_RS11985	COG1674	ftsk spoiiie
IPV69_RS11985	COG1196	nuclear chromosome segregation
IPV69_RS11990	COG0515	serine threonine protein kinase
IPV69_RS11995	COG2207	Transcriptional regulator
IPV69_RS11995	COG1609	Transcriptional regulator
IPV69_RS12005	COG1252	NADH dehydrogenase
IPV69_RS12010	COG2912	Transglutaminase-like superfamily
IPV69_RS12020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS12025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPV69_RS12030	COG0066	3-isopropylmalate dehydratase activity
IPV69_RS12035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPV69_RS12055	COG0402	S-adenosylhomocysteine deaminase activity
IPV69_RS12095	COG1764	response to oxidative stress
IPV69_RS12100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPV69_RS12120	COG1459	type II secretion system
IPV69_RS12125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS12135	COG5002	protein histidine kinase activity
IPV69_RS12150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPV69_RS12165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPV69_RS12170	COG0698	ribose 5-phosphate isomerase
IPV69_RS12215	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IPV69_RS12245	COG1429	ligase activity, forming nitrogen-metal bonds
IPV69_RS12250	COG4969	Belongs to the N-Me-Phe pilin family
IPV69_RS12255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IPV69_RS12255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IPV69_RS12255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IPV69_RS12270	COG0667	Aldo Keto reductase
IPV69_RS12325	COG1475	DNA binding
IPV69_RS12350	COG0515	serine threonine protein kinase
IPV69_RS12350	COG2815	serine threonine protein kinase
IPV69_RS12415	COG1475	DNA binding
IPV69_RS12445	COG1192	Involved in chromosome partitioning
IPV69_RS12470	COG0582	viral genome integration into host DNA
IPV69_RS12475	COG4974	Belongs to the 'phage' integrase family
IPV69_RS12480	COG4974	Belongs to the 'phage' integrase family
IPV69_RS12535	COG0432	Pfam Uncharacterised protein family UPF0047
IPV69_RS12550	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
IPV69_RS12550	COG3064	Membrane
IPV69_RS12550	COG1073	alpha beta
IPV69_RS12620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPV69_RS12625	COG1090	epimerase
IPV69_RS12640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPV69_RS12645	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPV69_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS12655	COG2197	response regulator
IPV69_RS12685	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
IPV69_RS12695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS12725	COG2815	serine threonine protein kinase
IPV69_RS12725	COG0515	serine threonine protein kinase
IPV69_RS12740	COG1199	ATP-dependent helicase activity
IPV69_RS12760	COG0357	Ribosomal RNA small subunit methyltransferase G
IPV69_RS12785	COG3119	arylsulfatase activity
IPV69_RS12800	COG0386	Belongs to the glutathione peroxidase family
IPV69_RS12810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPV69_RS12835	COG0398	Pfam SNARE associated Golgi protein
IPV69_RS12840	COG3481	metal-dependent phosphohydrolase, HD sub domain
IPV69_RS12890	COG1119	ATPase activity
IPV69_RS12895	COG0142	geranyltranstransferase activity
IPV69_RS12900	COG0494	nUDIX hydrolase
IPV69_RS12910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPV69_RS12915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IPV69_RS12920	COG0072	phenylalanine-tRNA ligase activity
IPV69_RS12920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPV69_RS12935	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IPV69_RS12955	COG0322	excinuclease ABC activity
IPV69_RS12975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS12980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPV69_RS12990	COG0028	Belongs to the TPP enzyme family
IPV69_RS13020	COG1131	(ABC) transporter
IPV69_RS13030	COG3119	arylsulfatase activity
IPV69_RS13060	COG0006	proline dipeptidase activity
IPV69_RS13100	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS13130	COG2814	Major facilitator Superfamily
IPV69_RS13140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IPV69_RS13145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPV69_RS13180	COG1301	dicarboxylic acid transport
IPV69_RS13185	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPV69_RS13200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPV69_RS13205	COG0805	protein transport
IPV69_RS13220	COG0512	Glutamine amidotransferase of anthranilate synthase
IPV69_RS13240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS13255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS13265	COG1663	tetraacyldisaccharide 4'-kinase activity
IPV69_RS13270	COG2211	Major facilitator Superfamily
IPV69_RS13285	COG0154	amidase activity
IPV69_RS13320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPV69_RS13340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPV69_RS13345	COG0673	inositol 2-dehydrogenase activity
IPV69_RS13350	COG1966	Carbon starvation protein
IPV69_RS13370	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPV69_RS13375	COG0673	inositol 2-dehydrogenase activity
IPV69_RS13380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPV69_RS13395	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS13410	COG1063	alcohol dehydrogenase
IPV69_RS13430	COG1368	sulfuric ester hydrolase activity
IPV69_RS13455	COG0561	phosphatase activity
IPV69_RS13470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IPV69_RS13485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPV69_RS13560	COG0859	PFAM glycosyl transferase family 9
IPV69_RS13565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPV69_RS13585	COG1363	Peptidase, m42
IPV69_RS13595	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IPV69_RS13595	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IPV69_RS13605	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IPV69_RS13620	COG0714	Associated with various cellular activities
IPV69_RS13650	COG3693	PFAM glycoside hydrolase, family 10
IPV69_RS13655	COG1011	Hydrolase
IPV69_RS13670	COG2207	Transcriptional regulator
IPV69_RS13670	COG1609	Transcriptional regulator
IPV69_RS13685	COG3119	arylsulfatase activity
IPV69_RS13725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IPV69_RS13740	COG1131	(ABC) transporter
IPV69_RS13775	COG1216	Glycosyl transferase, family 2
IPV69_RS13785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPV69_RS13790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPV69_RS13800	COG0537	adenosine 5'-monophosphoramidase activity
IPV69_RS13805	COG0577	efflux transmembrane transporter activity
IPV69_RS13820	COG3119	arylsulfatase activity
IPV69_RS13825	COG0488	(ABC) transporter
IPV69_RS13830	COG0673	inositol 2-dehydrogenase activity
IPV69_RS13840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPV69_RS13870	COG0217	transcriptional regulatory protein
IPV69_RS13875	COG3119	arylsulfatase activity
IPV69_RS13895	COG4999	Histidine kinase
IPV69_RS13895	COG2205	protein histidine kinase activity
IPV69_RS13895	COG3437	response regulator, receiver
IPV69_RS13895	COG3850	Histidine kinase
IPV69_RS13900	COG0110	maltose O-acetyltransferase activity
IPV69_RS13910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IPV69_RS13950	COG0667	Aldo Keto reductase
IPV69_RS14015	COG0165	Argininosuccinate lyase
IPV69_RS14095	COG0459	protein refolding
IPV69_RS14100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPV69_RS14110	COG0484	heat shock protein binding
IPV69_RS14115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPV69_RS14125	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IPV69_RS14140	COG5002	protein histidine kinase activity
IPV69_RS14150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IPV69_RS14160	COG3842	ATPase activity
IPV69_RS14165	COG3119	arylsulfatase activity
IPV69_RS14200	COG1692	metallophosphoesterase
IPV69_RS14205	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IPV69_RS14210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPV69_RS14255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPV69_RS14260	COG0719	Fe-S assembly protein
IPV69_RS14265	COG0396	ATPase activity
IPV69_RS14270	COG0719	Fe-S assembly protein
IPV69_RS14275	COG0316	Belongs to the HesB IscA family
IPV69_RS14315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPV69_RS14350	COG3664	PFAM glycoside hydrolase family 39
IPV69_RS14365	COG0284	orotidine-5'-phosphate decarboxylase activity
IPV69_RS14375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPV69_RS14395	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IPV69_RS14400	COG0750	zinc metalloprotease
IPV69_RS14410	COG1413	lyase activity
IPV69_RS14415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPV69_RS14435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IPV69_RS14440	COG1127	ABC transporter
IPV69_RS14455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IPV69_RS14480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPV69_RS14485	COG0470	DNA polymerase III
IPV69_RS14505	COG2346	COG2346, Truncated hemoglobins
IPV69_RS14510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IPV69_RS14525	COG0019	diaminopimelate decarboxylase activity
IPV69_RS14545	COG0803	Belongs to the bacterial solute-binding protein 9 family
IPV69_RS14550	COG1121	(ABC) transporter
IPV69_RS14555	COG1321	iron dependent repressor
IPV69_RS14555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPV69_RS14560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPV69_RS14570	COG4771	TonB-dependent receptor
IPV69_RS14575	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IPV69_RS14580	COG1132	(ABC) transporter
IPV69_RS14640	COG1216	Glycosyl transferase, family 2
IPV69_RS14680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPV69_RS14690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS14715	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IPV69_RS14725	COG0649	NAD binding
IPV69_RS14755	COG4191	Histidine kinase
IPV69_RS14775	COG3385	transposase activity
IPV69_RS14825	COG0745	RESPONSE REGULATOR receiver
IPV69_RS14840	COG2309	aminopeptidase activity
IPV69_RS14845	COG4650	regulator
IPV69_RS14860	COG0430	RNA-3'-phosphate cyclase activity
IPV69_RS14865	COG0515	serine threonine protein kinase
IPV69_RS14865	COG2815	serine threonine protein kinase
IPV69_RS14900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPV69_RS14930	COG1475	DNA binding
IPV69_RS14940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IPV69_RS14960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPV69_RS15000	COG0863	Belongs to the N(4) N(6)-methyltransferase family
IPV69_RS15020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IPV69_RS15025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPV69_RS15030	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS15030	COG3321	synthase
IPV69_RS15030	COG0604	alcohol dehydrogenase
IPV69_RS15040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IPV69_RS15045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IPV69_RS15110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPV69_RS15135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPV69_RS15170	COG0666	response to abiotic stimulus
IPV69_RS15195	COG3119	arylsulfatase activity
IPV69_RS15205	COG3119	arylsulfatase activity
IPV69_RS15215	COG2814	Major facilitator Superfamily
IPV69_RS15320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IPV69_RS15320	COG0517	IMP dehydrogenase activity
IPV69_RS15345	COG0489	protein tyrosine kinase activity
IPV69_RS15380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IPV69_RS15425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPV69_RS15430	COG1538	Outer membrane efflux protein
IPV69_RS15440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPV69_RS15465	COG3547	Transposase (IS116 IS110 IS902 family)
IPV69_RS15485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IPV69_RS15490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IPV69_RS15495	COG3118	belongs to the thioredoxin family
IPV69_RS15505	COG0318	PFAM AMP-dependent synthetase and ligase
IPV69_RS15520	COG3794	PFAM blue (type 1) copper domain protein
IPV69_RS15525	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS15550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPV69_RS15560	COG0753	catalase activity
IPV69_RS15565	COG2385	sporulation resulting in formation of a cellular spore
IPV69_RS15570	COG0202	RNA polymerase activity
IPV69_RS15620	COG0552	protein localization to endoplasmic reticulum
IPV69_RS15625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPV69_RS15630	COG1104	cysteine desulfurase activity
IPV69_RS15635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS15665	COG0784	Response regulator, receiver
IPV69_RS15665	COG2205	protein histidine kinase activity
IPV69_RS15665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IPV69_RS15665	COG2198	Histidine kinase
IPV69_RS15670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IPV69_RS15675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPV69_RS15700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS15710	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IPV69_RS15725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPV69_RS15730	COG0724	RNA recognition motif
IPV69_RS15740	COG2183	response to ionizing radiation
IPV69_RS15740	COG0539	negative regulation of cytoplasmic translation
IPV69_RS15760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPV69_RS15805	COG3385	transposase activity
IPV69_RS15840	COG0519	Catalyzes the synthesis of GMP from XMP
IPV69_RS15840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IPV69_RS15845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IPV69_RS15885	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IPV69_RS15900	COG2205	protein histidine kinase activity
IPV69_RS15905	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS15910	COG0515	serine threonine protein kinase
IPV69_RS15915	COG0788	formyltetrahydrofolate deformylase activity
IPV69_RS15940	COG2022	thiamine diphosphate biosynthetic process
IPV69_RS15950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPV69_RS15960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPV69_RS15975	COG0673	inositol 2-dehydrogenase activity
IPV69_RS15980	COG3409	Peptidoglycan-binding domain 1 protein
IPV69_RS16005	COG0673	inositol 2-dehydrogenase activity
IPV69_RS16015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IPV69_RS16025	COG0154	amidase activity
IPV69_RS16095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPV69_RS16105	COG0254	rRNA binding
IPV69_RS16115	COG3119	arylsulfatase activity
IPV69_RS16135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IPV69_RS16165	COG0616	signal peptide processing
IPV69_RS16165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPV69_RS16190	COG0653	protein targeting
IPV69_RS16250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPV69_RS16255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPV69_RS16290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IPV69_RS16305	COG3119	arylsulfatase activity
IPV69_RS16330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IPV69_RS16340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPV69_RS16345	COG1131	(ABC) transporter
IPV69_RS16350	COG3386	PFAM SMP-30 Gluconolaconase
IPV69_RS16360	COG0463	Glycosyl transferase, family 2
IPV69_RS16365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IPV69_RS16370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPV69_RS16405	COG0305	Participates in initiation and elongation during chromosome replication
IPV69_RS16410	COG0359	binds to the 23S rRNA
IPV69_RS16415	COG0629	single-stranded DNA binding
IPV69_RS16420	COG0360	Binds together with S18 to 16S ribosomal RNA
IPV69_RS16425	COG0193	aminoacyl-tRNA hydrolase activity
IPV69_RS16430	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPV69_RS16435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPV69_RS16440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPV69_RS16460	COG0714	Associated with various cellular activities
IPV69_RS16475	COG1793	dna ligase
IPV69_RS16475	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IPV69_RS16485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPV69_RS16540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS16545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPV69_RS16550	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS16555	COG1253	flavin adenine dinucleotide binding
IPV69_RS16565	COG0315	cyclic pyranopterin monophosphate synthase activity
IPV69_RS16570	COG0673	inositol 2-dehydrogenase activity
IPV69_RS16575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IPV69_RS16580	COG2226	methyltransferase
IPV69_RS16585	COG0163	prenyltransferase activity
IPV69_RS16605	COG2169	Transcriptional regulator
IPV69_RS16610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IPV69_RS16630	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPV69_RS16650	COG1309	transcriptional regulator
IPV69_RS16750	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS16770	COG0303	'Molybdopterin
IPV69_RS16810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPV69_RS16840	COG1272	protein, Hemolysin III
IPV69_RS16860	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IPV69_RS16865	COG0631	protein serine/threonine phosphatase activity
IPV69_RS16875	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IPV69_RS16880	COG3118	belongs to the thioredoxin family
IPV69_RS16950	COG0859	PFAM glycosyl transferase family 9
IPV69_RS16950	COG0457	Tetratricopeptide repeat
IPV69_RS16955	COG2239	Acts as a magnesium transporter
IPV69_RS16960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IPV69_RS16965	COG1177	transmembrane transport
IPV69_RS16990	COG1090	epimerase
IPV69_RS16995	COG0673	inositol 2-dehydrogenase activity
IPV69_RS17010	COG1045	serine acetyltransferase
IPV69_RS17015	COG1045	serine acetyltransferase
IPV69_RS17040	COG2755	lipolytic protein G-D-S-L family
IPV69_RS17040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IPV69_RS17080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPV69_RS17085	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS17090	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS17095	COG1216	Glycosyl transferase, family 2
IPV69_RS17100	COG1070	Carbohydrate kinase
IPV69_RS17105	COG4968	Prepilin-type N-terminal cleavage methylation domain
IPV69_RS17120	COG3830	Belongs to the UPF0237 family
IPV69_RS17120	COG0560	Phosphoserine phosphatase
IPV69_RS17130	COG0574	Belongs to the PEP-utilizing enzyme family
IPV69_RS17130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPV69_RS17155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS17165	COG0492	ferredoxin-NADP+ reductase activity
IPV69_RS17185	COG0667	Aldo Keto reductase
IPV69_RS17205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPV69_RS17290	COG0288	reversible hydration of carbon dioxide
IPV69_RS17305	COG0493	'glutamate synthase
IPV69_RS17305	COG0543	2 iron, 2 sulfur cluster binding
IPV69_RS17335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS17345	COG3119	arylsulfatase activity
IPV69_RS17370	COG2814	Major facilitator Superfamily
IPV69_RS17385	COG0445	tRNA wobble uridine modification
IPV69_RS17390	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPV69_RS17400	COG3119	arylsulfatase activity
IPV69_RS17410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IPV69_RS17460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPV69_RS17465	COG3385	transposase activity
IPV69_RS17485	COG0537	adenosine 5'-monophosphoramidase activity
IPV69_RS17525	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IPV69_RS17550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IPV69_RS17585	COG0527	aspartate kinase activity
IPV69_RS17595	COG4651	solute:proton antiporter activity
IPV69_RS17595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IPV69_RS17610	COG3119	arylsulfatase activity
IPV69_RS17645	COG0784	Response regulator, receiver
IPV69_RS17645	COG2205	protein histidine kinase activity
IPV69_RS17645	COG5002	protein histidine kinase activity
IPV69_RS17665	COG3119	arylsulfatase activity
IPV69_RS17670	COG5297	Belongs to the glycosyl hydrolase family 6
IPV69_RS17670	COG4733	cellulase activity
IPV69_RS17675	COG0151	Belongs to the GarS family
IPV69_RS17680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IPV69_RS17695	COG0542	response to heat
IPV69_RS17700	COG0586	Pfam SNARE associated Golgi protein
IPV69_RS17715	COG2208	phosphoserine phosphatase activity
IPV69_RS17755	COG0469	pyruvate kinase activity
IPV69_RS17810	COG0101	tRNA pseudouridine synthase activity
IPV69_RS17825	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPV69_RS17840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IPV69_RS17845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPV69_RS17850	COG0671	phosphoesterase, PA-phosphatase related
IPV69_RS17855	COG1450	Type ii and iii secretion system protein
IPV69_RS17865	COG0745	RESPONSE REGULATOR receiver
IPV69_RS17885	COG2201	protein-glutamate methylesterase activity
IPV69_RS17890	COG0745	RESPONSE REGULATOR receiver
IPV69_RS17905	COG0835	chemotaxis
IPV69_RS17910	COG0784	Response regulator, receiver
IPV69_RS17910	COG2198	Histidine kinase
IPV69_RS17910	COG0643	Histidine kinase
IPV69_RS17915	COG2204	response regulator
IPV69_RS17920	COG3852	Histidine kinase
IPV69_RS17940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPV69_RS17950	COG1078	dGTPase activity
IPV69_RS17955	COG0275	rRNA processing
IPV69_RS17965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS17970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPV69_RS18005	COG1403	HNH endonuclease
IPV69_RS18010	COG0793	Belongs to the peptidase S41A family
IPV69_RS18020	COG0018	arginyl-trna synthetase
IPV69_RS18025	COG0495	leucyl-tRNA aminoacylation
IPV69_RS18060	COG3119	arylsulfatase activity
IPV69_RS18065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPV69_RS18085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPV69_RS18090	COG2890	protein-(glutamine-N5) methyltransferase activity
IPV69_RS18150	COG0235	Class ii aldolase
IPV69_RS18155	COG1172	Belongs to the binding-protein-dependent transport system permease family
IPV69_RS18165	COG1129	ABC transporter
IPV69_RS18190	COG1131	(ABC) transporter
IPV69_RS18205	COG1413	lyase activity
IPV69_RS18225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IPV69_RS18230	COG1482	cell wall glycoprotein biosynthetic process
IPV69_RS18260	COG0724	RNA recognition motif
IPV69_RS18275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IPV69_RS18280	COG2081	HI0933 family
IPV69_RS18295	COG3507	Belongs to the glycosyl hydrolase 43 family
IPV69_RS18295	COG3693	PFAM glycoside hydrolase, family 10
IPV69_RS18295	COG2382	esterase
IPV69_RS18305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPV69_RS18310	COG2132	Multicopper oxidase
IPV69_RS18345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPV69_RS18350	COG0051	transcription antitermination factor activity, RNA binding
IPV69_RS18355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPV69_RS18360	COG0088	Forms part of the polypeptide exit tunnel
IPV69_RS18365	COG0089	rRNA binding
IPV69_RS18375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPV69_RS18380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPV69_RS18385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPV69_RS18390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPV69_RS18395	COG0255	Belongs to the universal ribosomal protein uL29 family
IPV69_RS18400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPV69_RS18405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPV69_RS18410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPV69_RS18415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPV69_RS18430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPV69_RS18435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPV69_RS18445	COG0200	Binds to the 23S rRNA
IPV69_RS18450	COG0201	protein transport
IPV69_RS18455	COG0024	Methionine aminopeptidase
IPV69_RS18460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IPV69_RS18465	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPV69_RS18470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPV69_RS18475	COG0202	RNA polymerase activity
IPV69_RS18480	COG0203	ribosomal protein L17
IPV69_RS18485	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS18490	COG0598	Magnesium transport protein CorA
IPV69_RS18515	COG1185	polyribonucleotide nucleotidyltransferase activity
IPV69_RS18520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPV69_RS18530	COG0071	Belongs to the small heat shock protein (HSP20) family
IPV69_RS18535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPV69_RS18540	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS18565	COG1136	(ABC) transporter
IPV69_RS18610	COG1132	(ABC) transporter
IPV69_RS18625	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IPV69_RS18625	COG2066	Belongs to the glutaminase family
IPV69_RS18635	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS18645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPV69_RS18655	COG1793	dna ligase
IPV69_RS18675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPV69_RS18680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IPV69_RS18695	COG0445	tRNA wobble uridine modification
IPV69_RS18705	COG4589	Belongs to the CDS family
IPV69_RS18750	COG1132	(ABC) transporter
IPV69_RS18830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPV69_RS18865	COG0714	Associated with various cellular activities
IPV69_RS18925	COG4658	electron transport chain
IPV69_RS18930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPV69_RS18940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IPV69_RS18970	COG1091	dTDP-4-dehydrorhamnose reductase activity
IPV69_RS18975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IPV69_RS18990	COG0556	nucleotide-excision repair
IPV69_RS19005	COG0039	L-malate dehydrogenase activity
IPV69_RS19020	COG4574	serine-type endopeptidase inhibitor activity
IPV69_RS19050	COG0612	Peptidase, M16
IPV69_RS19065	COG2819	hydrolase of the alpha beta superfamily
IPV69_RS19105	COG0811	peptide transport
IPV69_RS19110	COG0848	biopolymer transport protein
IPV69_RS19120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IPV69_RS19125	COG0416	fatty acid biosynthetic process
IPV69_RS19130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPV69_RS19135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IPV69_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS19145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPV69_RS19150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPV69_RS19165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IPV69_RS19175	COG0513	Belongs to the DEAD box helicase family
IPV69_RS19180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS19190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPV69_RS19195	COG2205	protein histidine kinase activity
IPV69_RS19195	COG0784	Response regulator, receiver
IPV69_RS19200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPV69_RS19240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IPV69_RS19250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPV69_RS19250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPV69_RS19255	COG1408	metallophosphoesterase
IPV69_RS19265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS19270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IPV69_RS19280	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPV69_RS19295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPV69_RS19315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPV69_RS19345	COG2226	methyltransferase
IPV69_RS19355	COG1505	serine-type exopeptidase activity
IPV69_RS19370	COG0803	Belongs to the bacterial solute-binding protein 9 family
IPV69_RS19375	COG1121	(ABC) transporter
IPV69_RS19390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPV69_RS19390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPV69_RS19440	COG3278	Belongs to the heme-copper respiratory oxidase family
IPV69_RS19450	COG2010	Cytochrome c
IPV69_RS19455	COG0348	domain, Protein
IPV69_RS19470	COG2217	Heavy metal translocating P-type atpase
IPV69_RS19485	COG0437	4 iron, 4 sulfur cluster binding
IPV69_RS19535	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS19540	COG3459	Glycosyltransferase 36 associated
IPV69_RS19545	COG0724	RNA recognition motif
IPV69_RS19550	COG3620	sequence-specific DNA binding
IPV69_RS19560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IPV69_RS19565	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IPV69_RS19570	COG4208	sulfate ABC transporter
IPV69_RS19650	COG3209	COG3209 Rhs family protein
IPV69_RS19660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPV69_RS19690	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPV69_RS19695	COG0567	Dehydrogenase, E1 component
IPV69_RS19720	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPV69_RS19725	COG2084	Dehydrogenase
IPV69_RS19730	COG2815	serine threonine protein kinase
IPV69_RS19730	COG0515	serine threonine protein kinase
IPV69_RS19750	COG0107	imidazoleglycerol-phosphate synthase activity
IPV69_RS19780	COG0534	Mate efflux family protein
IPV69_RS19795	COG1595	DNA-templated transcription, initiation
IPV69_RS19805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IPV69_RS19835	COG1104	cysteine desulfurase activity
IPV69_RS19850	COG0745	RESPONSE REGULATOR receiver
IPV69_RS19855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IPV69_RS19880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IPV69_RS19895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPV69_RS19955	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS20005	COG1846	Transcriptional regulator
IPV69_RS20015	COG0577	efflux transmembrane transporter activity
IPV69_RS20015	COG1136	(ABC) transporter
IPV69_RS20020	COG1136	(ABC) transporter
IPV69_RS20020	COG0577	efflux transmembrane transporter activity
IPV69_RS20025	COG1538	Outer membrane efflux protein
IPV69_RS20065	COG2770	Histidine kinase
IPV69_RS20065	COG2208	phosphoserine phosphatase activity
IPV69_RS20100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IPV69_RS20105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IPV69_RS20105	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IPV69_RS20110	COG2382	esterase
IPV69_RS20115	COG1776	CheC inhibitor of MCP methylation
IPV69_RS20115	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPV69_RS20120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPV69_RS20125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IPV69_RS20140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPV69_RS20145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPV69_RS20195	COG4537	Required for transformation and DNA binding
IPV69_RS20225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPV69_RS20270	COG3119	arylsulfatase activity
IPV69_RS20295	COG3119	arylsulfatase activity
IPV69_RS20350	COG1597	lipid kinase activity
IPV69_RS20355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IPV69_RS20370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IPV69_RS20375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPV69_RS20395	COG0012	GTP binding
IPV69_RS20425	COG1643	Atp-dependent helicase
IPV69_RS20485	COG3385	transposase activity
IPV69_RS20490	COG1164	Oligoendopeptidase f
IPV69_RS20515	COG3119	arylsulfatase activity
IPV69_RS20520	COG3119	arylsulfatase activity
IPV69_RS20530	COG0586	Pfam SNARE associated Golgi protein
IPV69_RS20540	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IPV69_RS20560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPV69_RS20580	COG1957	nucleoside hydrolase
IPV69_RS20590	COG3119	arylsulfatase activity
IPV69_RS20635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPV69_RS20655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IPV69_RS20660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPV69_RS20670	COG0528	UMP kinase activity
IPV69_RS20680	COG2835	tetraacyldisaccharide 4'-kinase activity
IPV69_RS20695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IPV69_RS20695	COG1796	DNA polymerase
IPV69_RS20710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IPV69_RS20740	COG0142	geranyltranstransferase activity
IPV69_RS20750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPV69_RS20775	COG0509	glycine decarboxylation via glycine cleavage system
IPV69_RS20780	COG1396	sequence-specific DNA binding
IPV69_RS20785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPV69_RS20790	COG1228	amidohydrolase
IPV69_RS20795	COG1228	amidohydrolase
IPV69_RS20800	COG0247	lactate metabolic process
IPV69_RS20805	COG0277	FAD linked oxidase domain protein
IPV69_RS20815	COG2268	Band 7 protein
IPV69_RS20835	COG0515	serine threonine protein kinase
IPV69_RS20835	COG2815	serine threonine protein kinase
IPV69_RS20845	COG0137	argininosuccinate synthase activity
IPV69_RS20860	COG0302	gtp cyclohydrolase
IPV69_RS20915	COG3622	Belongs to the hyi family
IPV69_RS20920	COG1063	alcohol dehydrogenase
IPV69_RS20925	COG0156	8-amino-7-oxononanoate synthase activity
IPV69_RS20940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPV69_RS20955	COG2226	methyltransferase
IPV69_RS20990	COG3708	Transcriptional regulator
IPV69_RS20990	COG2207	Transcriptional regulator
IPV69_RS21005	COG0657	acetylesterase activity
IPV69_RS21005	COG2755	lipolytic protein G-D-S-L family
IPV69_RS21045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPV69_RS21055	COG1082	Xylose isomerase domain protein TIM barrel
IPV69_RS21065	COG1073	alpha beta
IPV69_RS21080	COG0275	rRNA processing
IPV69_RS21090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPV69_RS21100	COG2207	Transcriptional regulator
IPV69_RS21100	COG1609	Transcriptional regulator
IPV69_RS21130	COG3119	arylsulfatase activity
IPV69_RS21135	COG0641	radical SAM
IPV69_RS21140	COG3119	arylsulfatase activity
IPV69_RS21145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IPV69_RS21170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IPV69_RS21170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IPV69_RS21195	COG0180	Tryptophanyl-tRNA synthetase
IPV69_RS21200	COG3654	unkown
IPV69_RS21210	COG1064	alcohol dehydrogenase
IPV69_RS21220	COG0538	isocitrate dehydrogenase activity
IPV69_RS21245	COG0673	inositol 2-dehydrogenase activity
IPV69_RS21305	COG0058	SHG alpha-glucan phosphorylase activity
IPV69_RS21345	COG0736	holo-[acyl-carrier-protein] synthase activity
IPV69_RS21350	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IPV69_RS21355	COG0174	glutamine synthetase
IPV69_RS21370	COG0347	Belongs to the P(II) protein family
IPV69_RS21380	COG4585	Histidine kinase
IPV69_RS21390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPV69_RS21395	COG0004	ammonium transporteR
IPV69_RS21405	COG0004	ammonium transporteR
IPV69_RS21415	COG0004	ammonium transporteR
IPV69_RS21420	COG0481	GTPase activity
IPV69_RS21425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPV69_RS21435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPV69_RS21460	COG2721	sulfolactate sulfo-lyase activity
IPV69_RS21470	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPV69_RS21470	COG0022	dehydrogenase e1 component
IPV69_RS21490	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IPV69_RS21505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IPV69_RS21525	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS21545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IPV69_RS21550	COG1418	mRNA catabolic process
IPV69_RS21585	COG2020	methyltransferase activity
IPV69_RS21605	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IPV69_RS21645	COG1028	Short-chain dehydrogenase reductase Sdr
IPV69_RS21690	COG1902	pentaerythritol trinitrate reductase activity
IPV69_RS21720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IPV69_RS21745	COG1215	transferase activity, transferring glycosyl groups
IPV69_RS21750	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS21770	COG0285	dihydrofolate synthase activity
IPV69_RS21775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPV69_RS21780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPV69_RS21785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IPV69_RS21800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPV69_RS21805	COG2165	general secretion pathway protein
IPV69_RS21820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS21830	COG1595	DNA-templated transcription, initiation
IPV69_RS21850	COG0673	inositol 2-dehydrogenase activity
IPV69_RS21855	COG3693	PFAM glycoside hydrolase, family 10
IPV69_RS21855	COG3509	depolymerase
IPV69_RS21860	COG0756	dUTP diphosphatase activity
IPV69_RS21865	COG1674	ftsk spoiiie
IPV69_RS21875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPV69_RS21890	COG3119	arylsulfatase activity
IPV69_RS21920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPV69_RS21930	COG0494	nUDIX hydrolase
IPV69_RS21935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPV69_RS21935	COG0758	DNA mediated transformation
IPV69_RS21945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPV69_RS21960	COG1758	RNA polymerase activity
IPV69_RS21965	COG0194	GDP metabolic process
IPV69_RS21970	COG1561	YicC-like family, N-terminal region
IPV69_RS21980	COG0149	triose-phosphate isomerase activity
IPV69_RS21985	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IPV69_RS22000	COG0484	heat shock protein binding
IPV69_RS22030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPV69_RS22045	COG1069	ribulokinase activity
IPV69_RS22055	COG2032	superoxide dismutase activity
IPV69_RS22080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPV69_RS22085	COG2897	thiosulfate sulfurtransferase activity
IPV69_RS22100	COG3300	MHYT domain
IPV69_RS22100	COG5001	Diguanylate cyclase
IPV69_RS22110	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IPV69_RS22130	COG0671	phosphoesterase, PA-phosphatase related
IPV69_RS22145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IPV69_RS22150	COG0563	adenylate kinase activity
IPV69_RS22155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPV69_RS22170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPV69_RS22175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPV69_RS22180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IPV69_RS22185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPV69_RS22210	COG1595	DNA-templated transcription, initiation
IPV69_RS22225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IPV69_RS22235	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPV69_RS22240	COG0508	dehydrogenase complex catalyzes the overall conversion of
IPV69_RS22240	COG0022	dehydrogenase e1 component
IPV69_RS22245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IPV69_RS22265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IPV69_RS22275	COG2203	Gaf domain
IPV69_RS22275	COG2199	diguanylate cyclase activity
IPV69_RS22295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IPV69_RS22305	COG0534	Mate efflux family protein
IPV69_RS22310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPV69_RS22315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPV69_RS22340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPV69_RS22350	COG0564	pseudouridine synthase activity
IPV69_RS22380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IPV69_RS22385	COG2814	Major facilitator Superfamily
IPV69_RS22395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPV69_RS22425	COG1254	Belongs to the acylphosphatase family
IPV69_RS22445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPV69_RS22450	COG3609	addiction module antidote protein, CC2985 family
IPV69_RS22465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPV69_RS22485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPV69_RS22505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPV69_RS22535	COG0475	glutathione-regulated potassium exporter activity
IPV69_RS22535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IPV69_RS22550	COG0653	protein targeting
IPV69_RS22565	COG1690	Belongs to the RtcB family
IPV69_RS22570	COG2089	acid synthase
IPV69_RS22575	COG1083	cytidylyl-transferase
IPV69_RS22575	COG2755	lipolytic protein G-D-S-L family
IPV69_RS22595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IPV69_RS22600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPV69_RS22615	COG2866	Carboxypeptidase
IPV69_RS22625	COG1722	exodeoxyribonuclease VII activity
IPV69_RS22635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPV69_RS22685	COG0275	rRNA processing
IPV69_RS22700	COG2001	Belongs to the MraZ family
IPV69_RS22720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPV69_RS22725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPV69_RS22740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPV69_RS22745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPV69_RS22750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPV69_RS22765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IPV69_RS22770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS22775	COG0740	serine-type endopeptidase activity
IPV69_RS22780	COG0740	serine-type endopeptidase activity
IPV69_RS22800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPV69_RS22805	COG0148	phosphopyruvate hydratase activity
IPV69_RS22835	COG2207	Transcriptional regulator
IPV69_RS22835	COG1609	Transcriptional regulator
IPV69_RS22880	COG5001	Diguanylate cyclase
IPV69_RS22990	COG0646	methionine synthase
IPV69_RS22990	COG1410	methionine synthase
IPV69_RS23005	COG1994	Peptidase M50
IPV69_RS23030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IPV69_RS23035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IPV69_RS23050	COG0713	ATP synthesis coupled electron transport
IPV69_RS23065	COG1007	ATP synthesis coupled electron transport
IPV69_RS23080	COG4786	Flagellar basal body rod
IPV69_RS23085	COG0443	Heat shock 70 kDa protein
IPV69_RS23090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IPV69_RS23100	COG0793	Belongs to the peptidase S41A family
IPV69_RS23100	COG3409	Peptidoglycan-binding domain 1 protein
IPV69_RS23125	COG0504	CTP synthase activity
IPV69_RS23130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IPV69_RS23135	COG1040	competence protein
IPV69_RS23140	COG2226	methyltransferase
IPV69_RS23150	COG1131	(ABC) transporter
IPV69_RS23195	COG0714	Associated with various cellular activities
IPV69_RS23235	COG0114	fumarate hydratase activity
IPV69_RS23240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPV69_RS23270	COG1968	undecaprenyl-diphosphatase activity
IPV69_RS23275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPV69_RS23290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPV69_RS23330	COG1295	ribonuclease BN
IPV69_RS23335	COG0784	Response regulator, receiver
IPV69_RS23335	COG5002	protein histidine kinase activity
IPV69_RS23335	COG2198	Histidine kinase
IPV69_RS23340	COG0745	RESPONSE REGULATOR receiver
IPV69_RS23350	COG2205	protein histidine kinase activity
IPV69_RS23350	COG0784	Response regulator, receiver
IPV69_RS23370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPV69_RS23385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPV69_RS23395	COG0726	polysaccharide deacetylase
IPV69_RS23395	COG1649	PFAM Uncharacterised BCR, COG1649
IPV69_RS23400	COG2501	S4 domain
IPV69_RS23410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IPV69_RS23435	COG1918	ferrous iron import across plasma membrane
IPV69_RS23470	COG0515	serine threonine protein kinase
IPV69_RS23475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPV69_RS23480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPV69_RS23485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPV69_RS23495	COG0356	it plays a direct role in the translocation of protons across the membrane
IPV69_RS23530	COG2204	response regulator
IPV69_RS23545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPV69_RS23550	COG1121	(ABC) transporter
IPV69_RS23580	COG0714	Associated with various cellular activities
IPV69_RS23620	COG0187	DNA topoisomerase II activity
IPV69_RS23625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPV69_RS23650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IPV69_RS23655	COG0573	inorganic phosphate transmembrane transporter activity
IPV69_RS23665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IPV69_RS23715	COG0606	chelatase, subunit chli
IPV69_RS23735	COG3540	Alkaline phosphatase
IPV69_RS23740	COG3119	arylsulfatase activity
IPV69_RS23745	COG0475	glutathione-regulated potassium exporter activity
IPV69_RS23750	COG0584	glycerophosphoryl diester phosphodiesterase
IPV69_RS23800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IPV69_RS23820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPV69_RS23825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPV69_RS23845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPV69_RS23850	COG0081	regulation of translation
IPV69_RS23855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPV69_RS23860	COG0222	ribosome binding
IPV69_RS23885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPV69_RS23895	COG1063	alcohol dehydrogenase
IPV69_RS23905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IPV69_RS23920	COG0085	RNA polymerase activity
IPV69_RS23930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPV69_RS23965	COG0463	Glycosyl transferase, family 2
IPV69_RS24035	COG0321	lipoyl(octanoyl) transferase activity
IPV69_RS24035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IPV69_RS24050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPV69_RS24055	COG3253	May function as heme-dependent peroxidase
IPV69_RS24060	COG1473	amidohydrolase
IPV69_RS24080	COG0442	prolyl-tRNA aminoacylation
IPV69_RS24095	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPV69_RS24110	COG4166	transmembrane transport
IPV69_RS24115	COG0601	transmembrane transport
IPV69_RS24120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPV69_RS24130	COG0601	transmembrane transport
IPV69_RS24135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPV69_RS24145	COG4608	Belongs to the ABC transporter superfamily
IPV69_RS24195	COG4964	Belongs to the GSP D family
IPV69_RS24225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IPV69_RS24245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPV69_RS24250	COG1490	D-aminoacyl-tRNA deacylase activity
IPV69_RS24260	COG0454	-acetyltransferase
IPV69_RS24260	COG0456	acetyltransferase
IPV69_RS24295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPV69_RS24300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPV69_RS24305	COG0131	Imidazoleglycerol-phosphate dehydratase
IPV69_RS24325	COG0205	6-phosphofructokinase activity
IPV69_RS24335	COG0439	Biotin carboxylase
IPV69_RS24340	COG0511	ligase activity, forming carbon-carbon bonds
IPV69_RS24345	COG0006	proline dipeptidase activity
IPV69_RS24360	COG3119	arylsulfatase activity
IPV69_RS24400	COG3119	arylsulfatase activity
IPV69_RS24405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IPV69_RS24425	COG1191	sigma factor activity
IPV69_RS24440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPV69_RS24445	COG1045	serine acetyltransferase
IPV69_RS24460	COG0156	8-amino-7-oxononanoate synthase activity
IPV69_RS24470	COG1595	DNA-templated transcription, initiation
IPV69_RS24475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IPV69_RS24530	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IPV69_RS24540	COG3385	transposase activity
IPV69_RS24550	COG2814	Major facilitator Superfamily
IPV69_RS24580	COG1136	(ABC) transporter
IPV69_RS24625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IPV69_RS24630	COG2204	response regulator
IPV69_RS24640	COG0840	transmembrane signaling receptor activity
IPV69_RS24655	COG1408	metallophosphoesterase
IPV69_RS24665	COG3845	ABC transporter
IPV69_RS24670	COG1079	Belongs to the binding-protein-dependent transport system permease family
IPV69_RS24675	COG4603	Belongs to the binding-protein-dependent transport system permease family
IPV69_RS24680	COG1744	ABC transporter substrate-binding protein PnrA-like
IPV69_RS24685	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPV69_RS24690	COG0540	Belongs to the ATCase OTCase family
IPV69_RS24700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IPV69_RS24840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IPV69_RS24900	COG0616	signal peptide processing
IPV69_RS24910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPV69_RS24915	COG0450	alkyl hydroperoxide reductase
IPV69_RS24920	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPV69_RS24940	COG0058	SHG alpha-glucan phosphorylase activity
IPV69_RS24960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPV69_RS24965	COG0861	Integral membrane protein TerC family
IPV69_RS24990	COG1519	Transferase
IPV69_RS24995	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPV69_RS25010	COG5433	transposase activity
IPV69_RS25065	COG0277	FAD linked oxidase domain protein
IPV69_RS25085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IPV69_RS25085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IPV69_RS25105	COG0110	maltose O-acetyltransferase activity
IPV69_RS25110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPV69_RS25125	COG0367	asparagine synthase
IPV69_RS25130	COG1216	Glycosyl transferase, family 2
IPV69_RS25135	COG0105	UTP biosynthetic process
IPV69_RS25140	COG0175	sulfate reduction
IPV69_RS25155	COG0529	Catalyzes the synthesis of activated sulfate
IPV69_RS25175	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
IPV69_RS25180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IPV69_RS25185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IPV69_RS25195	COG0628	permease
IPV69_RS25225	COG3264	Mechanosensitive ion channel
IPV69_RS25225	COG1196	nuclear chromosome segregation
IPV69_RS25230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPV69_RS25270	COG1120	ATPase activity
IPV69_RS25275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPV69_RS25290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IPV69_RS25290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPV69_RS25335	COG3064	Membrane
IPV69_RS25410	COG2755	lipolytic protein G-D-S-L family
IPV69_RS25410	COG0657	acetylesterase activity
IPV69_RS25425	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IPV69_RS25430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IPV69_RS25440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IPV69_RS25450	COG0436	Aminotransferase
IPV69_RS25465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IPV69_RS25480	COG0577	efflux transmembrane transporter activity
IPV69_RS25485	COG0577	efflux transmembrane transporter activity
IPV69_RS25485	COG1136	(ABC) transporter
IPV69_RS25500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPV69_RS25550	COG1902	pentaerythritol trinitrate reductase activity
IPV69_RS25570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IPV69_RS25585	COG2176	DNA-directed DNA polymerase activity
IPV69_RS25590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IPV69_RS25595	COG0616	signal peptide processing
IPV69_RS25605	COG0561	phosphatase activity
IPV69_RS25615	COG2239	Acts as a magnesium transporter
IPV69_RS25620	COG0475	glutathione-regulated potassium exporter activity
IPV69_RS25630	COG0494	nUDIX hydrolase
IPV69_RS25655	COG1335	isochorismatase
IPV69_RS25670	COG0784	Response regulator, receiver
IPV69_RS25670	COG2198	Histidine kinase
IPV69_RS25670	COG2205	protein histidine kinase activity
IPV69_RS25745	COG0583	DNA-binding transcription factor activity
IPV69_RS25750	COG1116	anion transmembrane transporter activity
IPV69_RS25750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IPV69_RS25755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IPV69_RS25765	COG1116	anion transmembrane transporter activity
IPV69_RS25765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IPV69_RS25770	COG1116	anion transmembrane transporter activity
IPV69_RS25780	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPV69_RS25785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IPV69_RS25790	COG0243	molybdopterin cofactor binding
IPV69_RS25945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IPV69_RS25950	COG3485	protocatechuate 3,4-dioxygenase
IPV69_RS25960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IPV69_RS25995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IPV69_RS26025	COG1160	GTP binding
IPV69_RS26030	COG1082	Xylose isomerase domain protein TIM barrel
IPV69_RS26035	COG1063	alcohol dehydrogenase
IPV69_RS26040	COG2205	protein histidine kinase activity
IPV69_RS26050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IPV69_RS26060	COG0215	cysteine-tRNA ligase activity
IPV69_RS26070	COG2204	response regulator
IPV69_RS26075	COG0181	hydroxymethylbilane synthase activity
IPV69_RS26090	COG2234	aminopeptidase activity
IPV69_RS26105	COG0673	inositol 2-dehydrogenase activity
IPV69_RS26110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPV69_RS26155	COG1832	CoA-binding protein
IPV69_RS26170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPV69_RS26180	COG0644	oxidoreductase
IPV69_RS26190	COG1116	anion transmembrane transporter activity
IPV69_RS26195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IPV69_RS26200	COG0583	DNA-binding transcription factor activity
IPV69_RS26230	COG0135	phosphoribosylanthranilate isomerase activity
IPV69_RS26240	COG2514	catechol 2,3-dioxygenase activity
IPV69_RS26275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPV69_RS26280	COG1611	Belongs to the LOG family
IPV69_RS26285	COG1073	alpha beta
IPV69_RS26290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPV69_RS26305	COG0713	ATP synthesis coupled electron transport
IPV69_RS26325	COG0456	acetyltransferase
IPV69_RS26340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IPV69_RS26345	COG1408	metallophosphoesterase
IPV69_RS26355	COG0784	Response regulator, receiver
IPV69_RS26355	COG2205	protein histidine kinase activity
IPV69_RS26360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IPV69_RS26365	COG0191	fructose-bisphosphate aldolase activity
IPV69_RS26375	COG0259	pyridoxamine-phosphate oxidase activity
IPV69_RS26380	COG0720	synthase
IPV69_RS26400	COG2072	flavoprotein involved in K transport
IPV69_RS26415	COG2144	transferase activity, transferring acyl groups
IPV69_RS26420	COG0438	transferase activity, transferring glycosyl groups
IPV69_RS26460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPV69_RS26470	COG2322	membrane
IPV69_RS26475	COG1999	signal sequence binding
IPV69_RS26480	COG0842	Transport permease protein
IPV69_RS26520	COG0617	tRNA 3'-terminal CCA addition
IPV69_RS26600	COG1278	Cold shock
IPV69_RS26605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IPV69_RS26615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPV69_RS26630	COG1506	peptidase
IPV69_RS26630	COG0823	Involved in the tonB-independent uptake of proteins
IPV69_RS26675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPV69_RS26755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IPV69_RS26765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IPV69_RS26770	COG3002	Belongs to the UPF0753 family
IPV69_RS26775	COG0175	sulfate reduction
IPV69_RS26795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPV69_RS26820	COG3119	arylsulfatase activity
IPV69_RS26925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IPV69_RS26945	COG3547	Transposase (IS116 IS110 IS902 family)
IPV69_RS26970	COG1228	amidohydrolase
IPV69_RS27020	COG1595	DNA-templated transcription, initiation
IPV69_RS27025	COG0134	indole-3-glycerol-phosphate synthase activity
IPV69_RS27040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPV69_RS27050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPV69_RS27055	COG3385	transposase activity