locus-tag	class	description
H9L05_RS00010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L05_RS00025	COG3275	phosphorelay sensor kinase activity
H9L05_RS00055	COG4948	Mandelate Racemase Muconate Lactonizing
H9L05_RS00080	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS00090	COG3618	amidohydrolase
H9L05_RS00095	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS00120	COG1629	transport
H9L05_RS00120	COG4206	TonB-dependent receptor
H9L05_RS00125	COG1629	transport
H9L05_RS00165	COG4191	Histidine kinase
H9L05_RS00180	COG0084	hydrolase, TatD family'
H9L05_RS00190	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS00200	COG0438	transferase activity, transferring glycosyl groups
H9L05_RS00305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L05_RS00310	COG1335	isochorismatase
H9L05_RS00325	COG0579	oxidoreductase
H9L05_RS00365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9L05_RS00380	COG0217	transcriptional regulatory protein
H9L05_RS00395	COG0110	maltose O-acetyltransferase activity
H9L05_RS00405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9L05_RS00475	COG0527	aspartate kinase activity
H9L05_RS00485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9L05_RS00495	COG0702	epimerase
H9L05_RS00510	COG1064	alcohol dehydrogenase
H9L05_RS00520	COG0288	reversible hydration of carbon dioxide
H9L05_RS00550	COG0489	protein tyrosine kinase activity
H9L05_RS00555	COG2244	polysaccharide biosynthetic process
H9L05_RS00575	COG0438	transferase activity, transferring glycosyl groups
H9L05_RS00590	COG0297	glycogen (starch) synthase activity
H9L05_RS00590	COG0438	transferase activity, transferring glycosyl groups
H9L05_RS00595	COG1216	Glycosyl transferase, family 2
H9L05_RS00595	COG0463	Glycosyl transferase, family 2
H9L05_RS00605	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H9L05_RS00610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L05_RS00620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9L05_RS00625	COG4310	Domain of unknown function (DUF2172)
H9L05_RS00650	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H9L05_RS00660	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9L05_RS00670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9L05_RS00675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9L05_RS00685	COG2198	Histidine kinase
H9L05_RS00685	COG0643	Histidine kinase
H9L05_RS00740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L05_RS00750	COG5002	protein histidine kinase activity
H9L05_RS00750	COG3850	Histidine kinase
H9L05_RS00755	COG0745	RESPONSE REGULATOR receiver
H9L05_RS00800	COG3279	Response regulator of the LytR AlgR family
H9L05_RS00805	COG3275	phosphorelay sensor kinase activity
H9L05_RS00815	COG1131	(ABC) transporter
H9L05_RS00830	COG1011	Hydrolase
H9L05_RS00845	COG0126	phosphoglycerate kinase activity
H9L05_RS00870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L05_RS00875	COG1846	Transcriptional regulator
H9L05_RS00880	COG1764	response to oxidative stress
H9L05_RS00910	COG0045	succinate-CoA ligase (ADP-forming) activity
H9L05_RS00915	COG1764	response to oxidative stress
H9L05_RS00925	COG4585	Histidine kinase
H9L05_RS00935	COG2197	response regulator
H9L05_RS00960	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9L05_RS01015	COG0024	Methionine aminopeptidase
H9L05_RS01050	COG3275	phosphorelay sensor kinase activity
H9L05_RS01055	COG3279	Response regulator of the LytR AlgR family
H9L05_RS01075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9L05_RS01105	COG2124	cytochrome p450
H9L05_RS01130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9L05_RS01135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9L05_RS01160	COG1053	succinate dehydrogenase
H9L05_RS01175	COG0038	chloride channel
H9L05_RS01185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9L05_RS01200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L05_RS01210	COG0772	Belongs to the SEDS family
H9L05_RS01220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L05_RS01230	COG0768	penicillin binding
H9L05_RS01240	COG0275	rRNA processing
H9L05_RS01245	COG2001	Belongs to the MraZ family
H9L05_RS01265	COG3279	Response regulator of the LytR AlgR family
H9L05_RS01270	COG2202	Pas domain
H9L05_RS01270	COG2205	protein histidine kinase activity
H9L05_RS01300	COG1233	COG1233 Phytoene dehydrogenase and related
H9L05_RS01305	COG1595	DNA-templated transcription, initiation
H9L05_RS01320	COG1024	Enoyl-CoA hydratase
H9L05_RS01325	COG2333	competence protein COMEC
H9L05_RS01325	COG0658	competence protein
H9L05_RS01335	COG1702	phosphate starvation-inducible protein PhoH
H9L05_RS01350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9L05_RS01365	COG0300	oxidoreductase activity
H9L05_RS01385	COG2197	response regulator
H9L05_RS01395	COG3665	Urea carboxylase-associated protein
H9L05_RS01430	COG0420	3'-5' exonuclease activity
H9L05_RS01435	COG0419	ATPase involved in DNA repair
H9L05_RS01440	COG0419	ATPase involved in DNA repair
H9L05_RS01455	COG3118	belongs to the thioredoxin family
H9L05_RS01485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9L05_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS01540	COG0443	Heat shock 70 kDa protein
H9L05_RS01555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9L05_RS01565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9L05_RS01570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9L05_RS01570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9L05_RS01585	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS01590	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9L05_RS01670	COG0671	phosphoesterase, PA-phosphatase related
H9L05_RS01680	COG0671	phosphoesterase, PA-phosphatase related
H9L05_RS01710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9L05_RS01750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9L05_RS01775	COG1428	Deoxynucleoside kinase
H9L05_RS01825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L05_RS01835	COG3590	peptidase
H9L05_RS01840	COG3590	peptidase
H9L05_RS01845	COG1570	exodeoxyribonuclease VII activity
H9L05_RS01855	COG1722	exodeoxyribonuclease VII activity
H9L05_RS01885	COG3685	Protein conserved in bacteria
H9L05_RS01955	COG0824	Thioesterase
H9L05_RS01970	COG0009	L-threonylcarbamoyladenylate synthase
H9L05_RS01990	COG0542	response to heat
H9L05_RS01995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9L05_RS02000	COG1363	Peptidase, m42
H9L05_RS02005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9L05_RS02010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9L05_RS02020	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9L05_RS02050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9L05_RS02070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9L05_RS02070	COG0662	Cupin 2, conserved barrel domain protein
H9L05_RS02075	COG0412	Dienelactone hydrolase
H9L05_RS02115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L05_RS02130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L05_RS02155	COG0497	DNA recombination
H9L05_RS02195	COG0037	tRNA processing
H9L05_RS02200	COG0039	L-malate dehydrogenase activity
H9L05_RS02215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9L05_RS02220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9L05_RS02230	COG0438	transferase activity, transferring glycosyl groups
H9L05_RS02240	COG0316	Belongs to the HesB IscA family
H9L05_RS02255	COG1668	transmembrane transport
H9L05_RS02260	COG4152	abc transporter atp-binding protein
H9L05_RS02275	COG0484	heat shock protein binding
H9L05_RS02280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9L05_RS02285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9L05_RS02290	COG0563	adenylate kinase activity
H9L05_RS02300	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H9L05_RS02320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9L05_RS02340	COG0463	Glycosyl transferase, family 2
H9L05_RS02340	COG1216	Glycosyl transferase, family 2
H9L05_RS02350	COG1216	Glycosyl transferase, family 2
H9L05_RS02365	COG1216	Glycosyl transferase, family 2
H9L05_RS02375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L05_RS02380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9L05_RS02395	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS02435	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS02460	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS02475	COG0463	Glycosyl transferase, family 2
H9L05_RS02495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L05_RS02505	COG0367	asparagine synthase
H9L05_RS02520	COG0791	NLP P60 protein
H9L05_RS02550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L05_RS02605	COG2814	Major facilitator Superfamily
H9L05_RS02660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H9L05_RS02670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9L05_RS02685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9L05_RS02690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L05_RS02700	COG0469	pyruvate kinase activity
H9L05_RS02705	COG0268	Binds directly to 16S ribosomal RNA
H9L05_RS02715	COG0357	Ribosomal RNA small subunit methyltransferase G
H9L05_RS02730	COG0343	queuine tRNA-ribosyltransferase activity
H9L05_RS02750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9L05_RS02765	COG1228	amidohydrolase
H9L05_RS02790	COG4206	TonB-dependent receptor
H9L05_RS02790	COG1629	transport
H9L05_RS02815	COG0626	cystathionine gamma-synthase activity
H9L05_RS02825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9L05_RS02835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9L05_RS02840	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9L05_RS02845	COG0193	aminoacyl-tRNA hydrolase activity
H9L05_RS02870	COG1217	gtp-binding protein TYPA
H9L05_RS02875	COG3361	conserved protein (COG2071)
H9L05_RS02900	COG4251	negative regulation of phosphorylation
H9L05_RS02905	COG4251	negative regulation of phosphorylation
H9L05_RS02910	COG0784	Response regulator, receiver
H9L05_RS02920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L05_RS02945	COG1872	DUF167
H9L05_RS02960	COG2234	aminopeptidase activity
H9L05_RS02965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9L05_RS03020	COG4953	penicillin-binding protein 1C
H9L05_RS03045	COG1012	belongs to the aldehyde dehydrogenase family
H9L05_RS03050	COG2207	Transcriptional regulator
H9L05_RS03065	COG0596	Alpha beta hydrolase
H9L05_RS03075	COG0632	four-way junction helicase activity
H9L05_RS03085	COG2996	Protein conserved in bacteria
H9L05_RS03090	COG0702	epimerase
H9L05_RS03110	COG3608	succinylglutamate desuccinylase aspartoacylase
H9L05_RS03120	COG4067	protein conserved in archaea
H9L05_RS03120	COG0189	ligase activity
H9L05_RS03140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9L05_RS03145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9L05_RS03175	COG3279	Response regulator of the LytR AlgR family
H9L05_RS03185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9L05_RS03200	COG3852	Histidine kinase
H9L05_RS03250	COG2351	hydroxyisourate hydrolase activity
H9L05_RS03260	COG3257	ureidoglycine aminohydrolase activity
H9L05_RS03280	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H9L05_RS03280	COG3608	succinylglutamate desuccinylase aspartoacylase
H9L05_RS03295	COG4771	TonB-dependent receptor
H9L05_RS03300	COG0702	epimerase
H9L05_RS03305	COG1418	mRNA catabolic process
H9L05_RS03330	COG2003	Belongs to the UPF0758 family
H9L05_RS03480	COG0612	Peptidase, M16
H9L05_RS03485	COG0538	isocitrate dehydrogenase activity
H9L05_RS03510	COG0436	Aminotransferase
H9L05_RS03515	COG2814	Major facilitator Superfamily
H9L05_RS03520	COG1064	alcohol dehydrogenase
H9L05_RS03540	COG0702	epimerase
H9L05_RS03545	COG4771	TonB-dependent receptor
H9L05_RS03565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L05_RS03570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L05_RS03580	COG2885	chlorophyll binding
H9L05_RS03600	COG1136	(ABC) transporter
H9L05_RS03605	COG0577	efflux transmembrane transporter activity
H9L05_RS03610	COG1136	(ABC) transporter
H9L05_RS03610	COG0577	efflux transmembrane transporter activity
H9L05_RS03620	COG4191	Histidine kinase
H9L05_RS03640	COG1506	peptidase
H9L05_RS03670	COG2326	polyphosphate kinase activity
H9L05_RS03685	COG1505	serine-type exopeptidase activity
H9L05_RS03730	COG2130	NADP-dependent
H9L05_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS03780	COG2080	2 iron, 2 sulfur cluster binding
H9L05_RS03785	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H9L05_RS03790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9L05_RS03840	COG0542	response to heat
H9L05_RS03915	COG0640	Transcriptional regulator
H9L05_RS03935	COG1012	belongs to the aldehyde dehydrogenase family
H9L05_RS03940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L05_RS03945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L05_RS03950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L05_RS03955	COG0649	NAD binding
H9L05_RS03960	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H9L05_RS03970	COG1034	ATP synthesis coupled electron transport
H9L05_RS03975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H9L05_RS03980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L05_RS03985	COG0839	Belongs to the complex I subunit 6 family
H9L05_RS03995	COG1132	(ABC) transporter
H9L05_RS04020	COG1595	DNA-templated transcription, initiation
H9L05_RS04025	COG0713	ATP synthesis coupled electron transport
H9L05_RS04030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9L05_RS04040	COG1007	ATP synthesis coupled electron transport
H9L05_RS04050	COG2885	chlorophyll binding
H9L05_RS04065	COG1131	(ABC) transporter
H9L05_RS04085	COG0590	tRNA wobble adenosine to inosine editing
H9L05_RS04105	COG0105	UTP biosynthetic process
H9L05_RS04110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9L05_RS04115	COG0545	Peptidyl-prolyl cis-trans isomerase
H9L05_RS04135	COG1381	Involved in DNA repair and RecF pathway recombination
H9L05_RS04170	COG0772	Belongs to the SEDS family
H9L05_RS04175	COG0768	penicillin binding
H9L05_RS04220	COG1278	Cold shock
H9L05_RS04225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H9L05_RS04235	COG0633	Ferredoxin
H9L05_RS04285	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H9L05_RS04285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L05_RS04290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L05_RS04295	COG1183	phosphatidylcholine synthase activity
H9L05_RS04320	COG0612	Peptidase, M16
H9L05_RS04350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L05_RS04355	COG0531	amino acid
H9L05_RS04365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9L05_RS04380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9L05_RS04405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L05_RS04415	COG0513	Belongs to the DEAD box helicase family
H9L05_RS04425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9L05_RS04460	COG0606	chelatase, subunit chli
H9L05_RS04465	COG0167	dihydroorotate dehydrogenase activity
H9L05_RS04520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9L05_RS04565	COG0702	epimerase
H9L05_RS04575	COG4771	TonB-dependent receptor
H9L05_RS04585	COG4771	TonB-dependent receptor
H9L05_RS04615	COG3940	Belongs to the glycosyl hydrolase 43 family
H9L05_RS04625	COG3940	Belongs to the glycosyl hydrolase 43 family
H9L05_RS04655	COG0149	triose-phosphate isomerase activity
H9L05_RS04685	COG1312	Catalyzes the dehydration of D-mannonate
H9L05_RS04690	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
H9L05_RS04720	COG1073	alpha beta
H9L05_RS04765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L05_RS04800	COG0776	regulation of translation
H9L05_RS04810	COG0629	single-stranded DNA binding
H9L05_RS04840	COG0183	Belongs to the thiolase family
H9L05_RS04855	COG1022	Amp-dependent synthetase and ligase
H9L05_RS04860	COG1022	Amp-dependent synthetase and ligase
H9L05_RS04865	COG1022	Amp-dependent synthetase and ligase
H9L05_RS04880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9L05_RS04895	COG1160	GTP binding
H9L05_RS04900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9L05_RS04905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9L05_RS04910	COG0730	response to heat
H9L05_RS04925	COG1104	cysteine desulfurase activity
H9L05_RS04940	COG0811	peptide transport
H9L05_RS04960	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H9L05_RS04980	COG0564	pseudouridine synthase activity
H9L05_RS04995	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L05_RS05000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9L05_RS05015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9L05_RS05050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H9L05_RS05055	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H9L05_RS05070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9L05_RS05190	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9L05_RS05210	COG0791	NLP P60 protein
H9L05_RS05225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L05_RS05250	COG1309	transcriptional regulator
H9L05_RS05255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9L05_RS05260	COG2234	aminopeptidase activity
H9L05_RS05265	COG1139	Iron-sulfur cluster binding protein
H9L05_RS05285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9L05_RS05285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9L05_RS05315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9L05_RS05320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9L05_RS05325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9L05_RS05330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9L05_RS05335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9L05_RS05385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9L05_RS05415	COG0321	lipoyl(octanoyl) transferase activity
H9L05_RS05420	COG0792	nuclease activity
H9L05_RS05430	COG0326	Molecular chaperone. Has ATPase activity
H9L05_RS05470	COG4774	siderophore transport
H9L05_RS05485	COG2814	Major facilitator Superfamily
H9L05_RS05515	COG1505	serine-type exopeptidase activity
H9L05_RS05520	COG4206	TonB-dependent receptor
H9L05_RS05575	COG1704	LemA family
H9L05_RS05605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L05_RS05605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L05_RS05615	COG0492	ferredoxin-NADP+ reductase activity
H9L05_RS05645	COG0598	Magnesium transport protein CorA
H9L05_RS05655	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H9L05_RS05690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L05_RS05710	COG2366	antibiotic biosynthetic process
H9L05_RS05720	COG1733	regulation of RNA biosynthetic process
H9L05_RS05725	COG1902	pentaerythritol trinitrate reductase activity
H9L05_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS05770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9L05_RS05830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L05_RS05840	COG0315	cyclic pyranopterin monophosphate synthase activity
H9L05_RS05845	COG0746	molybdenum cofactor guanylyltransferase activity
H9L05_RS05850	COG0314	molybdopterin synthase activity
H9L05_RS05860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9L05_RS05870	COG1073	alpha beta
H9L05_RS05890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9L05_RS05945	COG1640	4-alpha-glucanotransferase
H9L05_RS05950	COG0492	ferredoxin-NADP+ reductase activity
H9L05_RS05985	COG2115	Belongs to the xylose isomerase family
H9L05_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS06065	COG1609	Transcriptional regulator
H9L05_RS06120	COG1061	Type III restriction enzyme res subunit
H9L05_RS06160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9L05_RS06180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9L05_RS06185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9L05_RS06190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L05_RS06200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L05_RS06200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9L05_RS06235	COG0501	Belongs to the peptidase M48B family
H9L05_RS06260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L05_RS06265	COG0300	oxidoreductase activity
H9L05_RS06270	COG0596	Alpha beta hydrolase
H9L05_RS06270	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L05_RS06275	COG1027	Aspartate ammonia-lyase
H9L05_RS06290	COG0596	Alpha beta hydrolase
H9L05_RS06305	COG3590	peptidase
H9L05_RS06355	COG3507	Belongs to the glycosyl hydrolase 43 family
H9L05_RS06360	COG0673	inositol 2-dehydrogenase activity
H9L05_RS06390	COG4628	conserved protein (DUF2132)
H9L05_RS06395	COG3757	hydrolase, family 25
H9L05_RS06435	COG2226	methyltransferase
H9L05_RS06465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9L05_RS06480	COG0432	Pfam Uncharacterised protein family UPF0047
H9L05_RS06490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9L05_RS06500	COG0083	homoserine kinase activity
H9L05_RS06505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9L05_RS06520	COG0612	Peptidase, M16
H9L05_RS06530	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS06545	COG4221	oxidoreductase activity
H9L05_RS06565	COG2755	lipolytic protein G-D-S-L family
H9L05_RS06585	COG0346	lactoylglutathione lyase activity
H9L05_RS06595	COG2072	flavoprotein involved in K transport
H9L05_RS06600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9L05_RS06685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9L05_RS06690	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L05_RS06700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9L05_RS06720	COG0805	protein transport
H9L05_RS06740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L05_RS06755	COG2154	pterin-4-alpha-carbinolamine dehydratase
H9L05_RS06775	COG0483	inositol monophosphate 1-phosphatase activity
H9L05_RS06845	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9L05_RS06850	COG3852	Histidine kinase
H9L05_RS06895	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9L05_RS06990	COG0515	serine threonine protein kinase
H9L05_RS06990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9L05_RS06995	COG1040	competence protein
H9L05_RS07015	COG0708	Exodeoxyribonuclease III
H9L05_RS07030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9L05_RS07060	COG0306	phosphate transporter
H9L05_RS07065	COG0423	glycine-tRNA ligase activity
H9L05_RS07080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9L05_RS07125	COG0584	glycerophosphoryl diester phosphodiesterase
H9L05_RS07135	COG1607	acyl-coa hydrolase
H9L05_RS07145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9L05_RS07150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9L05_RS07160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9L05_RS07165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9L05_RS07175	COG1187	pseudouridine synthase activity
H9L05_RS07180	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9L05_RS07185	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9L05_RS07245	COG1137	ATPase activity
H9L05_RS07270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L05_RS07270	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
H9L05_RS07280	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L05_RS07290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9L05_RS07300	COG0297	glycogen (starch) synthase activity
H9L05_RS07305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9L05_RS07310	COG1404	Belongs to the peptidase S8 family
H9L05_RS07315	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9L05_RS07325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9L05_RS07325	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9L05_RS07335	COG1960	acyl-CoA dehydrogenase activity
H9L05_RS07345	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H9L05_RS07385	COG0247	lactate metabolic process
H9L05_RS07385	COG2181	nitrate reductase activity
H9L05_RS07415	COG0183	Belongs to the thiolase family
H9L05_RS07425	COG0101	tRNA pseudouridine synthase activity
H9L05_RS07430	COG1132	(ABC) transporter
H9L05_RS07460	COG1132	(ABC) transporter
H9L05_RS07470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L05_RS07480	COG0473	3-isopropylmalate dehydrogenase activity
H9L05_RS07490	COG1862	Preprotein translocase
H9L05_RS07500	COG0237	dephospho-CoA kinase activity
H9L05_RS07545	COG0668	transmembrane transport
H9L05_RS07560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9L05_RS07565	COG5002	protein histidine kinase activity
H9L05_RS07580	COG0531	amino acid
H9L05_RS07630	COG0697	spore germination
H9L05_RS07645	COG1266	CAAX protease self-immunity
H9L05_RS07650	COG0575	Belongs to the CDS family
H9L05_RS07660	COG0688	phosphatidylethanolamine metabolic process
H9L05_RS07665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L05_RS07665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L05_RS07685	COG1956	GAF domain-containing protein
H9L05_RS07705	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9L05_RS07710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9L05_RS07725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H9L05_RS07755	COG2201	protein-glutamate methylesterase activity
H9L05_RS07775	COG0442	prolyl-tRNA aminoacylation
H9L05_RS07830	COG0463	Glycosyl transferase, family 2
H9L05_RS07835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L05_RS07860	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS07865	COG0275	rRNA processing
H9L05_RS07870	COG0662	Cupin 2, conserved barrel domain protein
H9L05_RS07890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L05_RS07895	COG3279	Response regulator of the LytR AlgR family
H9L05_RS07905	COG0784	Response regulator, receiver
H9L05_RS07905	COG2205	protein histidine kinase activity
H9L05_RS07915	COG3015	lipoprotein NlpE involved in copper resistance
H9L05_RS07975	COG1024	Enoyl-CoA hydratase
H9L05_RS07995	COG1611	Belongs to the LOG family
H9L05_RS08035	COG5002	protein histidine kinase activity
H9L05_RS08095	COG3386	PFAM SMP-30 Gluconolaconase
H9L05_RS08100	COG2135	peptidase activity
H9L05_RS08115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L05_RS08170	COG0714	Associated with various cellular activities
H9L05_RS08210	COG1401	restriction endodeoxyribonuclease activity
H9L05_RS08250	COG1523	belongs to the glycosyl hydrolase 13 family
H9L05_RS08260	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9L05_RS08280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9L05_RS08300	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H9L05_RS08330	COG1473	amidohydrolase
H9L05_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS08385	COG0113	porphobilinogen synthase activity
H9L05_RS08420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9L05_RS08425	COG0006	proline dipeptidase activity
H9L05_RS08430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9L05_RS08440	COG0552	protein localization to endoplasmic reticulum
H9L05_RS08450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L05_RS08455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L05_RS08455	COG2755	lipolytic protein G-D-S-L family
H9L05_RS08460	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H9L05_RS08465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9L05_RS08500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9L05_RS08515	COG1295	ribonuclease BN
H9L05_RS08530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L05_RS08540	COG0156	8-amino-7-oxononanoate synthase activity
H9L05_RS08555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9L05_RS08575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9L05_RS08610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9L05_RS08630	COG0612	Peptidase, M16
H9L05_RS08655	COG3118	belongs to the thioredoxin family
H9L05_RS08670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9L05_RS08770	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L05_RS08780	COG0697	spore germination
H9L05_RS08830	COG1620	l-lactate permease
H9L05_RS08845	COG1733	regulation of RNA biosynthetic process
H9L05_RS08860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9L05_RS08870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9L05_RS08875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9L05_RS08890	COG2133	pyrroloquinoline quinone binding
H9L05_RS08900	COG1278	Cold shock
H9L05_RS08905	COG1187	pseudouridine synthase activity
H9L05_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS08940	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
H9L05_RS08960	COG0577	efflux transmembrane transporter activity
H9L05_RS08960	COG1136	(ABC) transporter
H9L05_RS08965	COG0577	efflux transmembrane transporter activity
H9L05_RS08965	COG1136	(ABC) transporter
H9L05_RS08970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L05_RS08985	COG0693	protein deglycase activity
H9L05_RS09055	COG0167	dihydroorotate dehydrogenase activity
H9L05_RS09060	COG0284	orotidine-5'-phosphate decarboxylase activity
H9L05_RS09065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9L05_RS09070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9L05_RS09075	COG0047	phosphoribosylformylglycinamidine synthase activity
H9L05_RS09080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9L05_RS09095	COG0151	Belongs to the GarS family
H9L05_RS09100	COG0151	Belongs to the GarS family
H9L05_RS09130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9L05_RS09140	COG0723	plastoquinol--plastocyanin reductase activity
H9L05_RS09225	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9L05_RS09235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9L05_RS09275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L05_RS09280	COG0436	Aminotransferase
H9L05_RS09285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L05_RS09330	COG1629	transport
H9L05_RS09340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9L05_RS09345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9L05_RS09360	COG2169	Transcriptional regulator
H9L05_RS09370	COG0277	FAD linked oxidase domain protein
H9L05_RS09380	COG0402	S-adenosylhomocysteine deaminase activity
H9L05_RS09450	COG1666	GTP binding
H9L05_RS09455	COG0861	Integral membrane protein TerC family
H9L05_RS09505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9L05_RS09535	COG4251	negative regulation of phosphorylation
H9L05_RS09540	COG0714	Associated with various cellular activities
H9L05_RS09570	COG1561	YicC-like family, N-terminal region
H9L05_RS09580	COG2234	aminopeptidase activity
H9L05_RS09595	COG0509	glycine decarboxylation via glycine cleavage system
H9L05_RS09610	COG0632	four-way junction helicase activity
H9L05_RS09615	COG0281	malic enzyme
H9L05_RS09615	COG0280	phosphate acetyltransferase
H9L05_RS09620	COG1388	LysM domain
H9L05_RS09620	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9L05_RS09625	COG0154	amidase activity
H9L05_RS09635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9L05_RS09655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9L05_RS09655	COG0237	dephospho-CoA kinase activity
H9L05_RS09685	COG0779	Required for maturation of 30S ribosomal subunits
H9L05_RS09690	COG0195	Participates in both transcription termination and antitermination
H9L05_RS09695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9L05_RS09695	COG5180	pathogenesis
H9L05_RS09715	COG1024	Enoyl-CoA hydratase
H9L05_RS09725	COG0756	dUTP diphosphatase activity
H9L05_RS09760	COG2873	o-acetylhomoserine
H9L05_RS09780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9L05_RS09795	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L05_RS09795	COG0596	Alpha beta hydrolase
H9L05_RS09800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9L05_RS09840	COG1914	H( )-stimulated, divalent metal cation uptake system
H9L05_RS09845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9L05_RS09900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9L05_RS09905	COG1960	acyl-CoA dehydrogenase activity
H9L05_RS09920	COG0489	protein tyrosine kinase activity
H9L05_RS09920	COG3206	protein involved in exopolysaccharide biosynthesis
H9L05_RS09930	COG4464	protein tyrosine phosphatase activity
H9L05_RS09935	COG3320	Male sterility
H9L05_RS09935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L05_RS09945	COG1809	phosphosulfolactate synthase activity
H9L05_RS09960	COG0586	Pfam SNARE associated Golgi protein
H9L05_RS09965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9L05_RS09970	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9L05_RS10000	COG0556	nucleotide-excision repair
H9L05_RS10030	COG2989	Protein conserved in bacteria
H9L05_RS10040	COG5002	protein histidine kinase activity
H9L05_RS10040	COG3850	Histidine kinase
H9L05_RS10095	COG2094	Belongs to the DNA glycosylase MPG family
H9L05_RS10115	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H9L05_RS10125	COG0463	Glycosyl transferase, family 2
H9L05_RS10140	COG1595	DNA-templated transcription, initiation
H9L05_RS10150	COG0194	GDP metabolic process
H9L05_RS10155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9L05_RS10160	COG0233	cytoplasmic translational termination
H9L05_RS10165	COG0528	UMP kinase activity
H9L05_RS10170	COG4770	biotin carboxylase activity
H9L05_RS10230	COG0081	regulation of translation
H9L05_RS10235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9L05_RS10240	COG0222	ribosome binding
H9L05_RS10250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9L05_RS10260	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9L05_RS10265	COG0049	tRNA binding
H9L05_RS10275	COG0051	transcription antitermination factor activity, RNA binding
H9L05_RS10285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9L05_RS10295	COG0089	rRNA binding
H9L05_RS10300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9L05_RS10305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9L05_RS10310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9L05_RS10315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9L05_RS10320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9L05_RS10325	COG0255	Belongs to the universal ribosomal protein uL29 family
H9L05_RS10330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9L05_RS10335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9L05_RS10340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9L05_RS10350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9L05_RS10355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9L05_RS10360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9L05_RS10370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9L05_RS10375	COG1841	ribosomal large subunit assembly
H9L05_RS10380	COG0200	Binds to the 23S rRNA
H9L05_RS10385	COG0201	protein transport
H9L05_RS10395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9L05_RS10400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9L05_RS10405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9L05_RS10410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9L05_RS10415	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9L05_RS10420	COG0202	RNA polymerase activity
H9L05_RS10425	COG0203	ribosomal protein L17
H9L05_RS10430	COG0148	phosphopyruvate hydratase activity
H9L05_RS10460	COG0248	Ppx GppA phosphatase
H9L05_RS10465	COG0116	Belongs to the methyltransferase superfamily
H9L05_RS10465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L05_RS10475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9L05_RS10505	COG0653	protein targeting
H9L05_RS10520	COG1473	amidohydrolase
H9L05_RS10540	COG1012	belongs to the aldehyde dehydrogenase family
H9L05_RS10545	COG0024	Methionine aminopeptidase
H9L05_RS10565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9L05_RS10630	COG3781	membrane
H9L05_RS10635	COG0583	DNA-binding transcription factor activity
H9L05_RS10640	COG0583	DNA-binding transcription factor activity
H9L05_RS10645	COG2855	membrane
H9L05_RS10690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9L05_RS10695	COG0052	Belongs to the universal ribosomal protein uS2 family
H9L05_RS10700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9L05_RS10705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9L05_RS10715	COG5002	protein histidine kinase activity
H9L05_RS10730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9L05_RS10770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L05_RS10775	COG2172	sigma factor antagonist activity
H9L05_RS10795	COG0516	GMP reductase activity
H9L05_RS10795	COG0517	IMP dehydrogenase activity
H9L05_RS10835	COG4774	siderophore transport
H9L05_RS10855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9L05_RS10880	COG2255	four-way junction helicase activity
H9L05_RS10890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9L05_RS10940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L05_RS10950	COG0572	uridine kinase
H9L05_RS10955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9L05_RS10965	COG0254	rRNA binding
H9L05_RS10980	COG0181	hydroxymethylbilane synthase activity
H9L05_RS10990	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9L05_RS10995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L05_RS11000	COG0601	transmembrane transport
H9L05_RS11025	COG2885	chlorophyll binding
H9L05_RS11055	COG0517	IMP dehydrogenase activity
H9L05_RS11055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9L05_RS11065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L05_RS11090	COG0799	negative regulation of ribosome biogenesis
H9L05_RS11115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L05_RS11125	COG1063	alcohol dehydrogenase
H9L05_RS11145	COG1774	PSP1 C-terminal conserved region
H9L05_RS11155	COG1278	Cold shock
H9L05_RS11160	COG1278	Cold shock
H9L05_RS11175	COG0702	epimerase
H9L05_RS11210	COG2373	Large extracellular alpha-helical protein
H9L05_RS11215	COG2373	Large extracellular alpha-helical protein
H9L05_RS11240	COG0633	Ferredoxin
H9L05_RS11245	COG0492	ferredoxin-NADP+ reductase activity
H9L05_RS11260	COG0626	cystathionine gamma-synthase activity
H9L05_RS11280	COG1830	Aldolase
H9L05_RS11285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9L05_RS11300	COG2885	chlorophyll binding
H9L05_RS11305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L05_RS11310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9L05_RS11320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9L05_RS11330	COG1253	flavin adenine dinucleotide binding
H9L05_RS11340	COG1522	sequence-specific DNA binding
H9L05_RS11350	COG3118	belongs to the thioredoxin family
H9L05_RS11365	COG1388	LysM domain
H9L05_RS11365	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9L05_RS11405	COG0612	Peptidase, M16
H9L05_RS11415	COG0006	proline dipeptidase activity
H9L05_RS11420	COG2885	chlorophyll binding
H9L05_RS11445	COG1796	DNA polymerase
H9L05_RS11445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9L05_RS11450	COG0859	PFAM glycosyl transferase family 9
H9L05_RS11530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H9L05_RS11535	COG1090	epimerase
H9L05_RS11540	COG0302	gtp cyclohydrolase
H9L05_RS11555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H9L05_RS11575	COG0335	large ribosomal subunit rRNA binding
H9L05_RS11580	COG0336	Belongs to the RNA methyltransferase TrmD family
H9L05_RS11585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9L05_RS11590	COG0228	four-way junction DNA binding
H9L05_RS11600	COG0564	pseudouridine synthase activity
H9L05_RS11605	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9L05_RS11615	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9L05_RS11620	COG3218	ABC-type transport auxiliary lipoprotein component
H9L05_RS11620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9L05_RS11650	COG2091	lysine biosynthetic process via aminoadipic acid
H9L05_RS11695	COG0346	lactoylglutathione lyase activity
H9L05_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS11725	COG2259	Doxx family
H9L05_RS11745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L05_RS11765	COG0737	Belongs to the 5'-nucleotidase family
H9L05_RS11770	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9L05_RS11780	COG1764	response to oxidative stress
H9L05_RS11835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9L05_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS11860	COG0702	epimerase
H9L05_RS11865	COG4771	TonB-dependent receptor
H9L05_RS11870	COG0702	epimerase
H9L05_RS11875	COG4771	TonB-dependent receptor
H9L05_RS11895	COG1629	transport
H9L05_RS11895	COG4206	TonB-dependent receptor
H9L05_RS11900	COG4771	TonB-dependent receptor
H9L05_RS11925	COG1136	(ABC) transporter
H9L05_RS11935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9L05_RS11955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9L05_RS11960	COG0784	Response regulator, receiver
H9L05_RS11965	COG4251	negative regulation of phosphorylation
H9L05_RS11975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H9L05_RS11980	COG2045	Belongs to the ComB family
H9L05_RS11985	COG1694	Mazg nucleotide pyrophosphohydrolase
H9L05_RS12005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9L05_RS12010	COG2226	methyltransferase
H9L05_RS12015	COG3800	Transcriptional regulator
H9L05_RS12015	COG1396	sequence-specific DNA binding
H9L05_RS12025	COG2224	Isocitrate lyase
H9L05_RS12030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H9L05_RS12045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9L05_RS12055	COG0137	argininosuccinate synthase activity
H9L05_RS12060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9L05_RS12090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9L05_RS12095	COG1629	transport
H9L05_RS12100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H9L05_RS12160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9L05_RS12180	COG0359	binds to the 23S rRNA
H9L05_RS12185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9L05_RS12190	COG0360	Binds together with S18 to 16S ribosomal RNA
H9L05_RS12225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9L05_RS12230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L05_RS12240	COG0109	protoheme IX farnesyltransferase activity
H9L05_RS12245	COG1845	cytochrome c oxidase, subunit III
H9L05_RS12250	COG1845	cytochrome c oxidase, subunit III
H9L05_RS12280	COG5000	phosphorelay sensor kinase activity
H9L05_RS12305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9L05_RS12315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L05_RS12315	COG3153	acetyltransferase
H9L05_RS12335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H9L05_RS12340	COG0196	riboflavin kinase activity
H9L05_RS12345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9L05_RS12350	COG1968	undecaprenyl-diphosphatase activity
H9L05_RS12360	COG2177	Part of the ABC transporter FtsEX involved in
H9L05_RS12385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9L05_RS12435	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9L05_RS12450	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9L05_RS12460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9L05_RS12470	COG1475	DNA binding
H9L05_RS12475	COG1192	Involved in chromosome partitioning
H9L05_RS12495	COG0504	CTP synthase activity
H9L05_RS12500	COG2027	D-alanyl-D-alanine carboxypeptidase
H9L05_RS12515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9L05_RS12520	COG2323	membrane
H9L05_RS12550	COG1501	Belongs to the glycosyl hydrolase 31 family
H9L05_RS12570	COG0405	Gamma-glutamyltransferase
H9L05_RS12590	COG0438	transferase activity, transferring glycosyl groups
H9L05_RS12620	COG0705	Rhomboid family
H9L05_RS12660	COG1649	PFAM Uncharacterised BCR, COG1649
H9L05_RS12750	COG2514	catechol 2,3-dioxygenase activity
H9L05_RS12760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L05_RS12785	COG3011	Protein conserved in bacteria
H9L05_RS12790	COG1846	Transcriptional regulator
H9L05_RS12795	COG0604	alcohol dehydrogenase
H9L05_RS12810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L05_RS12815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9L05_RS12830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L05_RS12840	COG0740	serine-type endopeptidase activity
H9L05_RS12845	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9L05_RS12855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L05_RS12865	COG1366	Belongs to the anti-sigma-factor antagonist family
H9L05_RS12870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9L05_RS12925	COG0438	transferase activity, transferring glycosyl groups
H9L05_RS12935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L05_RS12940	COG0861	Integral membrane protein TerC family
H9L05_RS12945	COG0463	Glycosyl transferase, family 2
H9L05_RS12960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9L05_RS12975	COG0010	Belongs to the arginase family
H9L05_RS12980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H9L05_RS12985	COG0018	arginyl-trna synthetase
H9L05_RS12995	COG0386	Belongs to the glutathione peroxidase family
H9L05_RS13010	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L05_RS13015	COG4771	TonB-dependent receptor
H9L05_RS13020	COG0702	epimerase
H9L05_RS13040	COG1629	transport
H9L05_RS13060	COG0513	Belongs to the DEAD box helicase family
H9L05_RS13065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L05_RS13075	COG0180	Tryptophanyl-tRNA synthetase
H9L05_RS13090	COG1234	tRNA 3'-trailer cleavage
H9L05_RS13105	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9L05_RS13125	COG1288	antiporter activity
H9L05_RS13140	COG0475	glutathione-regulated potassium exporter activity
H9L05_RS13140	COG0589	response to stress
H9L05_RS13160	COG2153	protein acetylation
H9L05_RS13180	COG0673	inositol 2-dehydrogenase activity
H9L05_RS13215	COG3275	phosphorelay sensor kinase activity
H9L05_RS13220	COG3279	Response regulator of the LytR AlgR family
H9L05_RS13235	COG3275	phosphorelay sensor kinase activity
H9L05_RS13255	COG1289	transmembrane transporter activity
H9L05_RS13260	COG0318	PFAM AMP-dependent synthetase and ligase
H9L05_RS13295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H9L05_RS13300	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9L05_RS13305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9L05_RS13320	COG0406	alpha-ribazole phosphatase activity
H9L05_RS13330	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9L05_RS13415	COG0659	secondary active sulfate transmembrane transporter activity
H9L05_RS13450	COG2824	Alkylphosphonate utilization operon protein PhnA
H9L05_RS13455	COG0012	GTP binding
H9L05_RS13470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9L05_RS13480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L05_RS13520	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9L05_RS13555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9L05_RS13560	COG2304	oxidoreductase activity
H9L05_RS13580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L05_RS13600	COG0436	Aminotransferase
H9L05_RS13610	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
H9L05_RS13615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9L05_RS13625	COG4948	Mandelate Racemase Muconate Lactonizing
H9L05_RS13655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L05_RS13690	COG0488	(ABC) transporter
H9L05_RS13695	COG0784	Response regulator, receiver
H9L05_RS13695	COG2205	protein histidine kinase activity
H9L05_RS13715	COG0754	glutathionylspermidine amidase activity
H9L05_RS13750	COG0346	lactoylglutathione lyase activity
H9L05_RS13755	COG0009	L-threonylcarbamoyladenylate synthase
H9L05_RS13760	COG0617	tRNA 3'-terminal CCA addition
H9L05_RS13800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9L05_RS13805	COG3876	Protein conserved in bacteria
H9L05_RS13810	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L05_RS13820	COG1017	nitric oxide dioxygenase activity
H9L05_RS13820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9L05_RS13835	COG2151	metal-sulfur cluster biosynthetic enzyme
H9L05_RS13850	COG3396	Phenylacetate-CoA oxygenase
H9L05_RS13855	COG1309	transcriptional regulator
H9L05_RS13875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L05_RS13940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9L05_RS13975	COG0297	glycogen (starch) synthase activity
H9L05_RS14020	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS14025	COG0489	protein tyrosine kinase activity
H9L05_RS14055	COG2610	gluconate transmembrane transporter activity
H9L05_RS14090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9L05_RS14095	COG1984	allophanate hydrolase subunit 2
H9L05_RS14105	COG1914	H( )-stimulated, divalent metal cation uptake system
H9L05_RS14140	COG4771	TonB-dependent receptor
H9L05_RS14195	COG2217	Heavy metal translocating P-type atpase
H9L05_RS14210	COG0628	permease
H9L05_RS14230	COG4221	oxidoreductase activity
H9L05_RS14245	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H9L05_RS14255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9L05_RS14310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L05_RS14325	COG1082	Xylose isomerase domain protein TIM barrel
H9L05_RS14330	COG2211	Major facilitator Superfamily
H9L05_RS14345	COG0673	inositol 2-dehydrogenase activity
H9L05_RS14360	COG1082	Xylose isomerase domain protein TIM barrel
H9L05_RS14365	COG2814	Major facilitator Superfamily
H9L05_RS14375	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L05_RS14380	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9L05_RS14410	COG0667	Aldo Keto reductase
H9L05_RS14425	COG0339	signal peptide processing
H9L05_RS14500	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9L05_RS14510	COG1690	Belongs to the RtcB family
H9L05_RS14515	COG1690	Belongs to the RtcB family
H9L05_RS14540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L05_RS14550	COG0783	Belongs to the Dps family
H9L05_RS14565	COG0321	lipoyl(octanoyl) transferase activity
H9L05_RS14565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9L05_RS14575	COG0205	6-phosphofructokinase activity
H9L05_RS14605	COG0784	Response regulator, receiver
H9L05_RS14605	COG5002	protein histidine kinase activity
H9L05_RS14605	COG2198	Histidine kinase
H9L05_RS14610	COG0784	Response regulator, receiver
H9L05_RS14610	COG2205	protein histidine kinase activity
H9L05_RS14635	COG1595	DNA-templated transcription, initiation
H9L05_RS14650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9L05_RS14660	COG3959	Transketolase, thiamine diphosphate binding domain
H9L05_RS14665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9L05_RS14670	COG3040	lipid binding
H9L05_RS14675	COG0739	heme binding
H9L05_RS14680	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9L05_RS14700	COG0305	Participates in initiation and elongation during chromosome replication
H9L05_RS14750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L05_RS14755	COG2814	Major facilitator Superfamily
H9L05_RS14785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9L05_RS14790	COG0384	phenazine biosynthesis protein PhzF
H9L05_RS14805	COG1538	Outer membrane efflux protein
H9L05_RS14835	COG2814	Major facilitator Superfamily
H9L05_RS14855	COG0584	glycerophosphoryl diester phosphodiesterase
H9L05_RS14870	COG2201	protein-glutamate methylesterase activity
H9L05_RS14900	COG3851	Histidine kinase
H9L05_RS14930	COG3387	PFAM Glycoside hydrolase 15-related
H9L05_RS14945	COG0745	RESPONSE REGULATOR receiver
H9L05_RS14945	COG2205	protein histidine kinase activity
H9L05_RS14945	COG3292	Two component regulator propeller
H9L05_RS14950	COG2205	protein histidine kinase activity
H9L05_RS14950	COG0745	RESPONSE REGULATOR receiver
H9L05_RS14950	COG3292	Two component regulator propeller
H9L05_RS14970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9L05_RS14970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9L05_RS14975	COG1621	beta-fructofuranosidase activity
H9L05_RS14980	COG2755	lipolytic protein G-D-S-L family
H9L05_RS15010	COG4771	TonB-dependent receptor
H9L05_RS15015	COG0702	epimerase
H9L05_RS15020	COG1917	Cupin 2, conserved barrel domain protein
H9L05_RS15035	COG0246	Mannitol dehydrogenase
H9L05_RS15040	COG2721	sulfolactate sulfo-lyase activity
H9L05_RS15075	COG0673	inositol 2-dehydrogenase activity
H9L05_RS15080	COG1012	belongs to the aldehyde dehydrogenase family
H9L05_RS15110	COG0577	efflux transmembrane transporter activity
H9L05_RS15110	COG1136	(ABC) transporter
H9L05_RS15115	COG1136	(ABC) transporter
H9L05_RS15130	COG5000	phosphorelay sensor kinase activity
H9L05_RS15165	COG0028	Belongs to the TPP enzyme family
H9L05_RS15170	COG0440	acetolactate synthase activity
H9L05_RS15175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9L05_RS15180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L05_RS15185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L05_RS15195	COG0066	3-isopropylmalate dehydratase activity
H9L05_RS15225	COG0538	isocitrate dehydrogenase activity
H9L05_RS15235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L05_RS15265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9L05_RS15290	COG3339	Conserved Protein
H9L05_RS15310	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H9L05_RS15355	COG0308	aminopeptidase N
H9L05_RS15365	COG2989	Protein conserved in bacteria
H9L05_RS15385	COG0513	Belongs to the DEAD box helicase family
H9L05_RS15390	COG0494	nUDIX hydrolase
H9L05_RS15405	COG5002	protein histidine kinase activity
H9L05_RS15430	COG1082	Xylose isomerase domain protein TIM barrel
H9L05_RS15440	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L05_RS15460	COG1629	transport
H9L05_RS15470	COG0400	carboxylic ester hydrolase activity
H9L05_RS15475	COG0346	lactoylglutathione lyase activity
H9L05_RS15520	COG0493	'glutamate synthase
H9L05_RS15525	COG0167	dihydroorotate dehydrogenase activity
H9L05_RS15530	COG1953	Uracil, thiamine, allantoin
H9L05_RS15535	COG0596	Alpha beta hydrolase
H9L05_RS15540	COG4251	negative regulation of phosphorylation
H9L05_RS15550	COG0402	S-adenosylhomocysteine deaminase activity
H9L05_RS15575	COG2084	Dehydrogenase
H9L05_RS15580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L05_RS15585	COG1741	Belongs to the pirin family
H9L05_RS15605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L05_RS15640	COG3781	membrane
H9L05_RS15705	COG0494	nUDIX hydrolase
H9L05_RS15735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9L05_RS15800	COG0825	malonyl-CoA metabolic process
H9L05_RS15805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L05_RS15810	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9L05_RS15845	COG3104	oligopeptide transport
H9L05_RS15850	COG0459	protein refolding
H9L05_RS15885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L05_RS15890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9L05_RS15920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9L05_RS15930	COG1663	tetraacyldisaccharide 4'-kinase activity
H9L05_RS15945	COG3250	beta-galactosidase activity
H9L05_RS16020	COG1528	Iron-storage protein
H9L05_RS16060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H9L05_RS16110	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L05_RS16165	COG0659	secondary active sulfate transmembrane transporter activity
H9L05_RS16200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L05_RS16210	COG0730	response to heat
H9L05_RS16220	COG4251	negative regulation of phosphorylation
H9L05_RS16285	COG0573	inorganic phosphate transmembrane transporter activity
H9L05_RS16295	COG0469	pyruvate kinase activity
H9L05_RS16330	COG4221	oxidoreductase activity
H9L05_RS16330	COG3321	synthase
H9L05_RS16330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9L05_RS16330	COG0604	alcohol dehydrogenase
H9L05_RS16340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9L05_RS16355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9L05_RS16385	COG2315	Protein conserved in bacteria
H9L05_RS16400	COG0495	leucyl-tRNA aminoacylation
H9L05_RS16405	COG0495	leucyl-tRNA aminoacylation
H9L05_RS16470	COG3250	beta-galactosidase activity
H9L05_RS16530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9L05_RS16555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9L05_RS16555	COG0758	DNA mediated transformation
H9L05_RS16565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9L05_RS16575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9L05_RS16580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L05_RS16595	COG1607	acyl-coa hydrolase
H9L05_RS16600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9L05_RS16605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9L05_RS16610	COG1301	dicarboxylic acid transport
H9L05_RS16620	COG0671	phosphoesterase, PA-phosphatase related
H9L05_RS16630	COG0022	dehydrogenase e1 component
H9L05_RS16650	COG3265	gluconokinase activity
H9L05_RS16660	COG3279	Response regulator of the LytR AlgR family
H9L05_RS16690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L05_RS16705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9L05_RS16745	COG1611	Belongs to the LOG family
H9L05_RS16765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9L05_RS16765	COG0574	Belongs to the PEP-utilizing enzyme family
H9L05_RS16845	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H9L05_RS16850	COG1902	pentaerythritol trinitrate reductase activity
H9L05_RS16855	COG0667	Aldo Keto reductase
H9L05_RS16870	COG1760	l-serine dehydratase
H9L05_RS16890	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9L05_RS16930	COG1678	Uncharacterized ACR, COG1678
H9L05_RS16955	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
H9L05_RS16960	COG4251	negative regulation of phosphorylation
H9L05_RS16965	COG4251	negative regulation of phosphorylation
H9L05_RS16970	COG5002	protein histidine kinase activity
H9L05_RS16975	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9L05_RS17005	COG1193	negative regulation of DNA recombination
H9L05_RS17020	COG0116	Belongs to the methyltransferase superfamily
H9L05_RS17025	COG0366	Alpha amylase catalytic
H9L05_RS17050	COG1741	Belongs to the pirin family
H9L05_RS17085	COG1051	belongs to the nudix hydrolase family
H9L05_RS17090	COG0513	Belongs to the DEAD box helicase family
H9L05_RS17095	COG2814	Major facilitator Superfamily
H9L05_RS17115	COG2010	Cytochrome c
H9L05_RS17120	COG1999	signal sequence binding
H9L05_RS17135	COG0667	Aldo Keto reductase
H9L05_RS17150	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
H9L05_RS17160	COG0668	transmembrane transport
H9L05_RS17165	COG2323	membrane
H9L05_RS17180	COG0038	chloride channel
H9L05_RS17185	COG0668	transmembrane transport
H9L05_RS17250	COG3634	alkyl hydroperoxide reductase activity
H9L05_RS17255	COG2207	Transcriptional regulator
H9L05_RS17255	COG1609	Transcriptional regulator
H9L05_RS17260	COG0667	Aldo Keto reductase
H9L05_RS17285	COG2080	2 iron, 2 sulfur cluster binding
H9L05_RS17305	COG1074	ATP-dependent DNA helicase activity
H9L05_RS17330	COG0513	Belongs to the DEAD box helicase family
H9L05_RS17340	COG0596	Alpha beta hydrolase
H9L05_RS17350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L05_RS17355	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS17375	COG1418	mRNA catabolic process
H9L05_RS17405	COG0584	glycerophosphoryl diester phosphodiesterase
H9L05_RS17415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L05_RS17425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9L05_RS17450	COG0671	phosphoesterase, PA-phosphatase related
H9L05_RS17465	COG0140	phosphoribosyl-ATP diphosphatase activity
H9L05_RS17465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9L05_RS17475	COG0107	imidazoleglycerol-phosphate synthase activity
H9L05_RS17480	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9L05_RS17485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9L05_RS17495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L05_RS17500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9L05_RS17575	COG0482	sulfurtransferase activity
H9L05_RS17580	COG0135	phosphoribosylanthranilate isomerase activity
H9L05_RS17610	COG0848	biopolymer transport protein
H9L05_RS17655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9L05_RS17675	COG0156	8-amino-7-oxononanoate synthase activity
H9L05_RS17680	COG0439	Biotin carboxylase
H9L05_RS17690	COG0739	heme binding
H9L05_RS17695	COG0492	ferredoxin-NADP+ reductase activity
H9L05_RS17700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L05_RS17705	COG1185	polyribonucleotide nucleotidyltransferase activity
H9L05_RS17710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9L05_RS17745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H9L05_RS17750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9L05_RS17755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9L05_RS17760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9L05_RS17810	COG1199	ATP-dependent helicase activity
H9L05_RS17810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9L05_RS17850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L05_RS17905	COG3278	Belongs to the heme-copper respiratory oxidase family
H9L05_RS17920	COG2010	Cytochrome c
H9L05_RS17945	COG0408	coproporphyrinogen oxidase activity
H9L05_RS17955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9L05_RS17980	COG1028	Short-chain dehydrogenase reductase Sdr
H9L05_RS18000	COG4783	chaperone-mediated protein folding
H9L05_RS18040	COG0488	(ABC) transporter
H9L05_RS18055	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L05_RS18075	COG2171	N-acyltransferase activity
H9L05_RS18100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L05_RS18110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9L05_RS18135	COG0602	queuosine metabolic process
H9L05_RS18150	COG0481	GTPase activity
H9L05_RS18180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L05_RS18180	COG1703	isobutyryl-CoA mutase activity
H9L05_RS18180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L05_RS18205	COG0768	penicillin binding
H9L05_RS18210	COG0768	penicillin binding
H9L05_RS18345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9L05_RS18375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L05_RS18380	COG0247	lactate metabolic process
H9L05_RS18410	COG1360	Flagellar Motor Protein
H9L05_RS18435	COG0517	IMP dehydrogenase activity
H9L05_RS18435	COG1125	glycine betaine transport
H9L05_RS18455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H9L05_RS18500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9L05_RS18500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9L05_RS18530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L05_RS18540	COG0358	DNA primase activity
H9L05_RS18550	COG0489	protein tyrosine kinase activity
H9L05_RS18555	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9L05_RS18560	COG3781	membrane
H9L05_RS18570	COG1063	alcohol dehydrogenase
H9L05_RS18580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9L05_RS18595	COG0745	RESPONSE REGULATOR receiver
H9L05_RS18625	COG2234	aminopeptidase activity
H9L05_RS18635	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
H9L05_RS18660	COG0802	atpase or kinase
H9L05_RS18710	COG2204	response regulator
H9L05_RS18725	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H9L05_RS18725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L05_RS18730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L05_RS18755	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L05_RS18770	COG0525	valine-tRNA ligase activity
H9L05_RS18785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9L05_RS18810	COG1054	Belongs to the UPF0176 family
H9L05_RS18855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9L05_RS18865	COG2095	MarC family integral membrane protein
H9L05_RS18870	COG0328	RNA-DNA hybrid ribonuclease activity
H9L05_RS18880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9L05_RS18890	COG0295	cytidine deaminase activity
H9L05_RS18920	COG2201	protein-glutamate methylesterase activity
H9L05_RS18925	COG4221	oxidoreductase activity
H9L05_RS18945	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9L05_RS18950	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H9L05_RS18975	COG0735	belongs to the Fur family
H9L05_RS18980	COG0450	alkyl hydroperoxide reductase
H9L05_RS18990	COG1162	GTPase activity
H9L05_RS19000	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9L05_RS19005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L05_RS19110	COG1216	Glycosyl transferase, family 2
H9L05_RS19110	COG1442	glycosyl transferase family 8
H9L05_RS19145	COG0598	Magnesium transport protein CorA
H9L05_RS19175	COG0531	amino acid
H9L05_RS19215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9L05_RS19220	COG0463	Glycosyl transferase, family 2
H9L05_RS19225	COG1215	transferase activity, transferring glycosyl groups
H9L05_RS19285	COG1012	belongs to the aldehyde dehydrogenase family
H9L05_RS19315	COG2223	nitrite transmembrane transporter activity
H9L05_RS19330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L05_RS19340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9L05_RS19350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9L05_RS19365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9L05_RS19370	COG0416	fatty acid biosynthetic process
H9L05_RS19375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L05_RS19380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9L05_RS19385	COG0511	ligase activity, forming carbon-carbon bonds
H9L05_RS19390	COG0439	Biotin carboxylase
H9L05_RS19410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9L05_RS19415	COG1950	PFAM Membrane protein of
H9L05_RS19425	COG1776	CheC inhibitor of MCP methylation
H9L05_RS19430	COG2198	Histidine kinase
H9L05_RS19430	COG0643	Histidine kinase
H9L05_RS19435	COG2201	protein-glutamate methylesterase activity
H9L05_RS19440	COG2201	protein-glutamate methylesterase activity
H9L05_RS19445	COG2201	protein-glutamate methylesterase activity
H9L05_RS19450	COG0835	chemotaxis
H9L05_RS19460	COG1754	DNA topoisomerase type I activity
H9L05_RS19460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9L05_RS19475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9L05_RS19490	COG0187	DNA topoisomerase II activity
H9L05_RS19585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H9L05_RS19635	COG2304	oxidoreductase activity
H9L05_RS19655	COG0183	Belongs to the thiolase family
H9L05_RS19700	COG0124	histidyl-tRNA synthetase
H9L05_RS19715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9L05_RS19735	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L05_RS19735	COG0022	dehydrogenase e1 component
H9L05_RS19770	COG1629	transport
H9L05_RS19780	COG1629	transport
H9L05_RS19780	COG4206	TonB-dependent receptor
H9L05_RS19815	COG0590	tRNA wobble adenosine to inosine editing
H9L05_RS19820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9L05_RS19840	COG1086	Polysaccharide biosynthesis protein
H9L05_RS19845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9L05_RS19850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H9L05_RS19870	COG2089	acid synthase
H9L05_RS19900	COG0531	amino acid
H9L05_RS19930	COG2884	Cell division ATP-binding protein ftsE
H9L05_RS19940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9L05_RS19950	COG0519	Catalyzes the synthesis of GMP from XMP
H9L05_RS19950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L05_RS19980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9L05_RS20025	COG1131	(ABC) transporter
H9L05_RS20030	COG4221	oxidoreductase activity
H9L05_RS20045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L05_RS20055	COG2318	DinB family
H9L05_RS20065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9L05_RS20070	COG2086	electron transfer activity
H9L05_RS20170	COG0133	tryptophan synthase activity
H9L05_RS20175	COG0135	phosphoribosylanthranilate isomerase activity
H9L05_RS20180	COG0134	indole-3-glycerol-phosphate synthase activity
H9L05_RS20185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9L05_RS20200	COG2819	hydrolase of the alpha beta superfamily
H9L05_RS20225	COG1629	transport
H9L05_RS20225	COG4206	TonB-dependent receptor
H9L05_RS20255	COG4771	TonB-dependent receptor
H9L05_RS20260	COG4771	TonB-dependent receptor
H9L05_RS20275	COG1404	Belongs to the peptidase S8 family
H9L05_RS20300	COG0022	dehydrogenase e1 component
H9L05_RS20325	COG1368	sulfuric ester hydrolase activity
H9L05_RS20345	COG2318	DinB family
H9L05_RS20360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H9L05_RS20390	COG4771	TonB-dependent receptor
H9L05_RS20395	COG4771	TonB-dependent receptor
H9L05_RS20400	COG0702	epimerase
H9L05_RS20405	COG3940	Belongs to the glycosyl hydrolase 43 family
H9L05_RS20410	COG3507	Belongs to the glycosyl hydrolase 43 family
H9L05_RS20430	COG0235	Class ii aldolase
H9L05_RS20435	COG2160	L-arabinose isomerase activity
H9L05_RS20465	COG3507	Belongs to the glycosyl hydrolase 43 family
H9L05_RS20470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9L05_RS20475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9L05_RS20485	COG1609	Transcriptional regulator
H9L05_RS20525	COG2755	lipolytic protein G-D-S-L family
H9L05_RS20595	COG0702	epimerase
H9L05_RS20600	COG1629	transport
H9L05_RS20605	COG1629	transport
H9L05_RS20635	COG0247	lactate metabolic process
H9L05_RS20640	COG1139	Iron-sulfur cluster binding protein
H9L05_RS20650	COG1556	Lactate utilization protein
H9L05_RS20665	COG1629	transport
H9L05_RS20670	COG1629	transport
H9L05_RS20675	COG3254	rhamnose metabolic process
H9L05_RS20760	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L05_RS20795	COG3275	phosphorelay sensor kinase activity
H9L05_RS20815	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H9L05_RS20835	COG3852	Histidine kinase
H9L05_RS20860	COG1473	amidohydrolase
H9L05_RS20875	COG5002	protein histidine kinase activity
H9L05_RS20920	COG3851	Histidine kinase
H9L05_RS20950	COG1253	flavin adenine dinucleotide binding
H9L05_RS21120	COG1404	Belongs to the peptidase S8 family
H9L05_RS21130	COG4677	pectinesterase activity
H9L05_RS21145	COG2205	protein histidine kinase activity
H9L05_RS21145	COG0745	RESPONSE REGULATOR receiver
H9L05_RS21145	COG3292	Two component regulator propeller
H9L05_RS21150	COG3292	Two component regulator propeller
H9L05_RS21150	COG2205	protein histidine kinase activity
H9L05_RS21150	COG0745	RESPONSE REGULATOR receiver
H9L05_RS21220	COG1609	Transcriptional regulator
H9L05_RS21225	COG1609	Transcriptional regulator
H9L05_RS21230	COG3279	Response regulator of the LytR AlgR family
H9L05_RS21295	COG3279	Response regulator of the LytR AlgR family
H9L05_RS21300	COG2972	Histidine kinase
H9L05_RS21380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9L05_RS21395	COG0154	amidase activity
H9L05_RS21425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H9L05_RS21585	COG5002	protein histidine kinase activity
H9L05_RS21595	COG4565	transcriptional regulatory protein
H9L05_RS21610	COG5002	protein histidine kinase activity
H9L05_RS21615	COG5002	protein histidine kinase activity
H9L05_RS21665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L05_RS21705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L05_RS21720	COG1431	PFAM Stem cell self-renewal protein Piwi
H9L05_RS21810	COG1742	UPF0060 membrane protein
H9L05_RS22010	COG2217	Heavy metal translocating P-type atpase
H9L05_RS22155	COG2197	response regulator
H9L05_RS22190	COG2132	Multicopper oxidase
H9L05_RS22345	COG1192	Involved in chromosome partitioning
H9L05_RS22350	COG4680	protein conserved in bacteria
H9L05_RS22495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L05_RS22510	COG2217	Heavy metal translocating P-type atpase
H9L05_RS22525	COG1742	UPF0060 membrane protein
H9L05_RS22555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9L05_RS22565	COG1730	sister chromatid segregation
H9L05_RS22580	COG1528	Iron-storage protein
H9L05_RS22730	COG1192	Involved in chromosome partitioning
H9L05_RS22765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs