locus-tag	class	description
GKZ67_RS00050	ENOG4105C3F	Signal peptidase i
GKZ67_RS00055	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GKZ67_RS00080	ENOG4107QJE	Chromosome Partitioning Protein
GKZ67_RS00085	ENOG4107W2A	UPF0173 metal-dependent hydrolase
GKZ67_RS00090	ENOG4105DEF	Extracellular solute-binding protein, family 5
GKZ67_RS00100	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKZ67_RS00110	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GKZ67_RS00115	ENOG4105DDI	hemolysin-type calcium-binding region
GKZ67_RS00120	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GKZ67_RS00125	ENOG4108ZP8	Acetolactate synthase small subunit
GKZ67_RS00130	ENOG4105C7K	acetolactate synthase
GKZ67_RS00135	ENOG4105C01	Dihydroxy-acid dehydratase
GKZ67_RS00140	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GKZ67_RS00145	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GKZ67_RS00155	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GKZ67_RS00170	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
GKZ67_RS00200	ENOG4107QMH	DNA methylase
GKZ67_RS00210	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKZ67_RS00215	ENOG4108JQ1	Dehydrogenase
GKZ67_RS00225	ENOG4105E9Z	Nad-dependent epimerase dehydratase
GKZ67_RS00230	ENOG4105C7W	Xanthine dehydrogenase
GKZ67_RS00235	ENOG4105C7W	Xanthine dehydrogenase
GKZ67_RS00240	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
GKZ67_RS00245	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
GKZ67_RS00255	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GKZ67_RS00260	ENOG4105CPC	Aldo Keto reductase
GKZ67_RS00280	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GKZ67_RS00285	ENOG4105DG4	malate L-lactate dehydrogenase
GKZ67_RS00305	ENOG4107R33	ppx gppa phosphatase
GKZ67_RS00310	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GKZ67_RS00330	ENOG4105CJN	penicillin-binding protein
GKZ67_RS00335	ENOG4105CJN	penicillin-binding protein
GKZ67_RS00340	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GKZ67_RS00375	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GKZ67_RS00445	ENOG410853W	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKZ67_RS00460	ENOG4105C19	ABC transporter
GKZ67_RS00470	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GKZ67_RS00480	ENOG4105C27	TonB-dependent Receptor Plug
GKZ67_RS00530	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GKZ67_RS00540	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GKZ67_RS00565	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GKZ67_RS00575	ENOG4105D16	lipopolysaccharide heptosyltransferase i
GKZ67_RS00600	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GKZ67_RS00610	ENOG4105BZU	Histidine kinase
GKZ67_RS00620	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GKZ67_RS00625	ENOG4108N5B	2-phosphosulfolactate phosphatase
GKZ67_RS00655	ENOG4105CUB	amino acid
GKZ67_RS00675	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GKZ67_RS00695	ENOG4105C02	permease
GKZ67_RS00730	ENOG410903D	sensor protein
GKZ67_RS00775	ENOG4105WH1	Two component transcriptional regulator luxr family
GKZ67_RS00790	ENOG4107S2Z	UPF0761 membrane protein
GKZ67_RS00870	ENOG4105BZU	Histidine kinase
GKZ67_RS00875	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GKZ67_RS00945	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GKZ67_RS00960	ENOG4105C9A	Phoh family
GKZ67_RS00965	ENOG4105VCH	membrane
GKZ67_RS00975	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GKZ67_RS01005	ENOG4105EMN	RNA polymerase sigma factor
GKZ67_RS01025	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GKZ67_RS01035	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GKZ67_RS01060	ENOG4105DYC	esterase
GKZ67_RS01120	ENOG4107YM1	mraZ protein
GKZ67_RS01125	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GKZ67_RS01135	ENOG4105CJN	penicillin-binding protein
GKZ67_RS01145	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GKZ67_RS01150	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GKZ67_RS01155	ENOG4105CNI	cell division protein FtsW
GKZ67_RS01160	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GKZ67_RS01165	ENOG4105DFU	Cell wall formation (By similarity)
GKZ67_RS01190	ENOG4105CA0	peroxidase
GKZ67_RS01195	ENOG4105CA0	peroxidase
GKZ67_RS01210	ENOG4105D05	Receptor
GKZ67_RS01235	ENOG4105CHR	reductase
GKZ67_RS01255	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GKZ67_RS01265	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GKZ67_RS01290	ENOG4105CQC	Prephenate dehydratase
GKZ67_RS01295	ENOG4105CHM	Aminotransferase
GKZ67_RS01305	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GKZ67_RS01315	ENOG4105DWV	Homoserine O-trans-acetylase
GKZ67_RS01330	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GKZ67_RS01335	ENOG4105C9K	Endothelin-converting enzyme 1
GKZ67_RS01350	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKZ67_RS01390	ENOG4105K70	DNA-binding protein
GKZ67_RS01430	ENOG4105C1G	acyl-Coa dehydrogenase
GKZ67_RS01440	ENOG4105CHU	acetyl-coa acetyltransferase
GKZ67_RS01455	ENOG4108IQE	Amp-dependent synthetase and ligase
GKZ67_RS01465	ENOG41088SP	formiminoglutamate hydrolase
GKZ67_RS01475	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKZ67_RS01495	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GKZ67_RS01500	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GKZ67_RS01505	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GKZ67_RS01565	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GKZ67_RS01570	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GKZ67_RS01580	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GKZ67_RS01585	ENOG4107RI6	Anthranilate phosphoribosyltransferase
GKZ67_RS01590	ENOG4105DDQ	anthranilate synthase
GKZ67_RS01595	ENOG4105CRQ	synthase (Component I)
GKZ67_RS01620	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GKZ67_RS01630	ENOG4105D74	hydrolase
GKZ67_RS01645	ENOG4105EQ0	Major Facilitator superfamily
GKZ67_RS01675	ENOG4105C26	Dehydrogenase
GKZ67_RS01695	ENOG4108JQB	penicillin-binding protein 1C
GKZ67_RS01710	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GKZ67_RS01715	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GKZ67_RS01755	ENOG4105MA4	psp1 domain protein
GKZ67_RS01765	ENOG4107QN2	dihydrolipoyl dehydrogenase
GKZ67_RS01775	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GKZ67_RS01785	ENOG4105WH1	Two component transcriptional regulator luxr family
GKZ67_RS01790	ENOG4105CPN	adenine deaminase
GKZ67_RS01805	ENOG4105CAT	Cytidine monophosphate kinase
GKZ67_RS01815	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GKZ67_RS01820	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GKZ67_RS01830	ENOG4108UVJ	appr-1-p processing domain protein
GKZ67_RS01845	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GKZ67_RS01870	ENOG4105CB2	alcohol dehydrogenase
GKZ67_RS01900	ENOG4105F32	YngK protein
GKZ67_RS01910	ENOG4105II7	pyrroline-5-carboxylate reductase
GKZ67_RS01915	ENOG4105K4T	epimerase
GKZ67_RS02005	ENOG4105CKK	Glycosyl transferase, family 2
GKZ67_RS02035	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GKZ67_RS02040	ENOG4108V06	Glutathione peroxidase
GKZ67_RS02045	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GKZ67_RS02060	ENOG4105C6E	dna polymerase iii
GKZ67_RS02130	ENOG4105W5Q	DNA repair protein (RadC
GKZ67_RS02155	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GKZ67_RS02170	ENOG4105CAQ	asparagine synthetase
GKZ67_RS02180	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GKZ67_RS02205	ENOG4105CKK	Glycosyl transferase, family 2
GKZ67_RS02235	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKZ67_RS02275	ENOG4105EXC	Acyl-transferase
GKZ67_RS02280	ENOG4107J0A	lipopolysaccharide biosynthetic process
GKZ67_RS02290	ENOG4107XU6	Glycosyl transferase (Group 1
GKZ67_RS02325	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GKZ67_RS02330	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GKZ67_RS02335	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GKZ67_RS02340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKZ67_RS02360	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKZ67_RS02380	ENOG4108IUX	(ABC) transporter
GKZ67_RS02400	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GKZ67_RS02450	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GKZ67_RS02455	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GKZ67_RS02460	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GKZ67_RS02490	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKZ67_RS02505	ENOG4105DQ4	alcohol dehydrogenase
GKZ67_RS02510	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GKZ67_RS02515	ENOG4105CDV	Ompa motb domain protein
GKZ67_RS02535	ENOG4105DG4	malate L-lactate dehydrogenase
GKZ67_RS02540	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GKZ67_RS02570	ENOG4105CNG	UPF0061 protein
GKZ67_RS02575	ENOG4105CNG	UPF0061 protein
GKZ67_RS02580	ENOG4107YB6	acetyltransferase, (GNAT) family
GKZ67_RS02695	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
GKZ67_RS02705	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GKZ67_RS02720	ENOG4105CPN	adenine deaminase
GKZ67_RS02725	ENOG4105FYV	Amp nucleosidase
GKZ67_RS02740	ENOG4105DCF	alanine dehydrogenase
GKZ67_RS02760	ENOG4105CPP	Dehydrogenase, E1 component
GKZ67_RS02785	ENOG4107S1Q	Phosphatase
GKZ67_RS02860	ENOG4105CBX	hi0933 family
GKZ67_RS02885	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
GKZ67_RS02890	ENOG4105CZK	Aspartate kinase
GKZ67_RS02910	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GKZ67_RS02915	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GKZ67_RS02980	ENOG4105BZ4	penicillin-binding protein
GKZ67_RS03005	ENOG4108URH	decarboxylase
GKZ67_RS03070	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GKZ67_RS03080	ENOG4107QYV	phosphohexose isomerase
GKZ67_RS03085	ENOG4107QP8	phosphohexose isomerase
GKZ67_RS03095	ENOG4105C84	Histidine ammonia-lyase
GKZ67_RS03110	ENOG4105CUT	histidyl-tRNA synthetase
GKZ67_RS03135	ENOG4105CGD	Nad-dependent epimerase dehydratase
GKZ67_RS03170	ENOG4105CDY	transcriptional regulatory protein
GKZ67_RS03175	ENOG4105BZU	Histidine kinase
GKZ67_RS03180	ENOG4105DY9	regulatoR
GKZ67_RS03240	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
GKZ67_RS03245	ENOG4105DT9	hydrolase family 43
GKZ67_RS03250	ENOG4108RWI	nicotinamidase
GKZ67_RS03255	ENOG4105DWT	malate dehydrogenase (quinone)
GKZ67_RS03265	ENOG4105VEQ	Cold shock protein
GKZ67_RS03280	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GKZ67_RS03285	ENOG4105DY9	regulatoR
GKZ67_RS03290	ENOG4105BZU	Histidine kinase
GKZ67_RS03300	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GKZ67_RS03320	ENOG4108IUM	Glycogen debranching enzyme
GKZ67_RS03325	ENOG4108IUM	Glycogen debranching enzyme
GKZ67_RS03340	ENOG4105BZU	Histidine kinase
GKZ67_RS03370	ENOG41090EK	ompa motb domain protein
GKZ67_RS03420	ENOG4107X42	5-methylthioadenosine S-adenosylhomocysteine nucleosidase
GKZ67_RS03460	ENOG4105DZR	Type I site-specific deoxyribonuclease
GKZ67_RS03560	ENOG4105CPC	Aldo Keto reductase
GKZ67_RS03570	ENOG4105ETE	Transcriptional regulator (LacI family
GKZ67_RS03625	ENOG4105C2I	pirin domain protein
GKZ67_RS03655	ENOG4105TT1	Ragb susd domain-containing protein
GKZ67_RS03675	ENOG4108HRK	Histidine kinase
GKZ67_RS03680	ENOG4108NEV	two component transcriptional regulator, LytTR family
GKZ67_RS03690	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GKZ67_RS03700	ENOG4106IPI	cyclase, family
GKZ67_RS03725	ENOG4105DY9	regulatoR
GKZ67_RS03730	ENOG4108HRK	Histidine kinase
GKZ67_RS03740	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GKZ67_RS03765	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
GKZ67_RS03780	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
GKZ67_RS03795	ENOG4105C7W	Xanthine dehydrogenase
GKZ67_RS03800	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
GKZ67_RS03805	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
GKZ67_RS03810	ENOG4105D6E	homoserine dehydrogenase
GKZ67_RS03825	ENOG4105D9R	oxidoreductase
GKZ67_RS03885	ENOG4105D2N	Aldolase
GKZ67_RS03915	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GKZ67_RS03920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GKZ67_RS03945	ENOG4105CA0	peroxidase
GKZ67_RS03985	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GKZ67_RS04025	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKZ67_RS04040	ENOG4105CND	Glycosyl transferase, family 2
GKZ67_RS04050	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
GKZ67_RS04055	ENOG4105C3Q	Glycosyl transferase, family 2
GKZ67_RS04095	ENOG4105W2Z	cytochrome C, class I
GKZ67_RS04125	ENOG4105C6Z	Gluconate
GKZ67_RS04130	ENOG4105T16	Transcriptional regulator (AraC family)
GKZ67_RS04275	ENOG4105CBD	Diacylglycerol kinase
GKZ67_RS04390	ENOG4105E0Y	RtcB Protein
GKZ67_RS04425	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GKZ67_RS04430	ENOG4108MGY	Histidine kinase
GKZ67_RS04435	ENOG4105BZU	Histidine kinase
GKZ67_RS04445	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GKZ67_RS04450	ENOG4105CTQ	phosphohexokinase
GKZ67_RS04490	ENOG4108YYS	metal-dependent hydrolase (By similarity)
GKZ67_RS04515	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GKZ67_RS04525	ENOG4108IXY	short-chain dehydrogenase reductase
GKZ67_RS04530	ENOG4105C1J	atp-dependent rna helicase
GKZ67_RS04535	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKZ67_RS04590	ENOG4105MIR	Phenylalanine 4-monooxygenase
GKZ67_RS04620	ENOG4105D1H	recombination factor protein RarA
GKZ67_RS04635	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GKZ67_RS04670	ENOG4105F8V	Hydrolase, tatD family
GKZ67_RS04675	ENOG4105HDK	L-asparaginase
GKZ67_RS04700	ENOG4105CHM	Aminotransferase
GKZ67_RS04710	ENOG4105C10	Electron transfer flavoprotein
GKZ67_RS04740	ENOG4105GR3	Histidine kinase
GKZ67_RS04775	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GKZ67_RS04790	ENOG4108R99	pseudouridine synthase
GKZ67_RS04820	ENOG4105CHR	reductase
GKZ67_RS04835	ENOG4105CY3	ABC transporter, permease
GKZ67_RS04850	ENOG4105EMU	Dehydrogenase
GKZ67_RS04880	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GKZ67_RS04890	ENOG4105CCU	oxidase (Subunit III)
GKZ67_RS04910	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
GKZ67_RS04935	ENOG4108I0Z	Aconitate hydratase
GKZ67_RS04995	ENOG41067HS	methyltransferase
GKZ67_RS05000	ENOG4105DU1	integral membrane protein, terc
GKZ67_RS05010	ENOG4105C1Q	protoporphyrinogen oxidase
GKZ67_RS05025	ENOG4105EUJ	GTP cyclohydrolase i
GKZ67_RS05070	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GKZ67_RS05085	ENOG4107QJT	sodium dicarboxylate symporter
GKZ67_RS05095	ENOG4105UNS	Pfam:DUF419
GKZ67_RS05125	ENOG4105C8T	Leucyl-tRNA synthetase
GKZ67_RS05130	ENOG4105C8T	Leucyl-tRNA synthetase
GKZ67_RS05135	ENOG4105DEN	Luciferase family
GKZ67_RS05140	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GKZ67_RS05145	ENOG4107SVH	Potassium channel protein
GKZ67_RS05165	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GKZ67_RS05175	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GKZ67_RS05185	ENOG4105D7N	magnesium and cobalt transport protein CorA
GKZ67_RS05205	ENOG4105K64	Glycosyl transferase, family 2
GKZ67_RS05220	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
GKZ67_RS05255	ENOG4107S5I	aldo keto reductase
GKZ67_RS05305	ENOG4105D5P	Methylmalonyl-coA mutase
GKZ67_RS05325	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GKZ67_RS05340	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GKZ67_RS05345	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GKZ67_RS05365	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GKZ67_RS05410	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GKZ67_RS05430	ENOG4105C5H	ABC transporter
GKZ67_RS05465	ENOG4107QYX	exodeoxyribonuclease v alpha
GKZ67_RS05505	ENOG4105CJ1	ABC, transporter
GKZ67_RS05510	ENOG4105CEY	Amp-dependent synthetase and ligase
GKZ67_RS05515	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GKZ67_RS05535	ENOG4105C5R	Aminotransferase
GKZ67_RS05550	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GKZ67_RS05555	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKZ67_RS05570	ENOG4105CNU	cell division protein FtsK
GKZ67_RS05595	ENOG4105C72	UPF0176 protein
GKZ67_RS05615	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GKZ67_RS05635	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GKZ67_RS05640	ENOG4107XM9	(LipO)protein
GKZ67_RS05700	ENOG4105CHU	acetyl-coa acetyltransferase
GKZ67_RS05710	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GKZ67_RS05715	ENOG4108UKI	Enoyl-CoA hydratase
GKZ67_RS05720	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
GKZ67_RS05725	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
GKZ67_RS05730	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
GKZ67_RS05735	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
GKZ67_RS05740	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GKZ67_RS05770	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
GKZ67_RS05780	ENOG4105D6J	arsenicaL-resistance protein
GKZ67_RS05785	ENOG4108UXE	Protein tyrosine phosphatase
GKZ67_RS05790	ENOG4105CH6	catalase
GKZ67_RS05810	ENOG4105ECP	epimerase
GKZ67_RS05820	ENOG4105CEV	competence damage-inducible protein
GKZ67_RS05840	ENOG4105CJ1	ABC, transporter
GKZ67_RS05850	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GKZ67_RS05855	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GKZ67_RS05960	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKZ67_RS05970	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GKZ67_RS05980	ENOG4105CSR	polyphosphate kinase 2
GKZ67_RS06005	ENOG4105C5H	ABC transporter
GKZ67_RS06065	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GKZ67_RS06095	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GKZ67_RS06100	ENOG4108SNX	Mammalian cell entry related domain protein
GKZ67_RS06140	ENOG4105C7K	acetolactate synthase
GKZ67_RS06175	ENOG4105KRF	dihydroneopterin aldolase
GKZ67_RS06250	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GKZ67_RS06275	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GKZ67_RS06300	ENOG4107TDE	lipolytic protein G-D-S-L family
GKZ67_RS06305	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GKZ67_RS06315	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GKZ67_RS06320	ENOG4105K5M	30s ribosomal protein S16
GKZ67_RS06330	ENOG4105C34	Pseudouridine synthase
GKZ67_RS06335	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GKZ67_RS06345	ENOG41068JE	domain protein
GKZ67_RS06365	ENOG4105C1V	Peptidase, M16
GKZ67_RS06375	ENOG4105P4J	Allophanate hydrolase, subunit 1
GKZ67_RS06385	ENOG4105E7W	lamb ycsf family protein
GKZ67_RS06390	ENOG4105C5A	transporter
GKZ67_RS06400	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GKZ67_RS06415	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GKZ67_RS06425	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GKZ67_RS06450	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GKZ67_RS06470	ENOG4107ZYR	domain protein
GKZ67_RS06480	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
GKZ67_RS06485	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GKZ67_RS06495	ENOG4107QX3	carboxylase
GKZ67_RS06505	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GKZ67_RS06510	ENOG4105EEQ	Na H antiporter
GKZ67_RS06535	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GKZ67_RS06540	ENOG4105DUX	Transporter
GKZ67_RS06545	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GKZ67_RS06550	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GKZ67_RS06580	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GKZ67_RS06585	ENOG4105CRQ	synthase (Component I)
GKZ67_RS06615	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GKZ67_RS06620	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GKZ67_RS06645	ENOG4105DCF	alanine dehydrogenase
GKZ67_RS06655	ENOG4107XWI	flavin reductase domain protein, FMN-binding
GKZ67_RS06690	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKZ67_RS06695	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GKZ67_RS06715	ENOG4105BZU	Histidine kinase
GKZ67_RS06760	ENOG4105D5P	Methylmalonyl-coA mutase
GKZ67_RS06785	ENOG4105CGH	5'-nucleotidase
GKZ67_RS06800	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GKZ67_RS06810	ENOG4107RBB	ABC transporter, permease
GKZ67_RS06820	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GKZ67_RS06870	ENOG4105BZU	Histidine kinase
GKZ67_RS06875	ENOG410812K	response regulator receiver protein
GKZ67_RS06885	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
GKZ67_RS06890	ENOG4105VDW	Csbd family
GKZ67_RS06900	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GKZ67_RS06905	ENOG4105K56	Transcriptional regulator
GKZ67_RS06935	ENOG4105CDV	Ompa motb domain protein
GKZ67_RS06935	ENOG4105CDV	Ompa motb domain protein
GKZ67_RS06965	ENOG4108S4H	thioesterase Superfamily protein
GKZ67_RS06970	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GKZ67_RS06980	ENOG4108R6K	riboflavin synthase, subunit alpha
GKZ67_RS07065	ENOG4105C02	permease
GKZ67_RS07070	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
GKZ67_RS07090	ENOG4105DF5	DNA topoisomerase IV, subunit A
GKZ67_RS07100	ENOG41077A9	carbonic anhydrase
GKZ67_RS07105	ENOG41062D9	Histidine kinase
GKZ67_RS07110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKZ67_RS07140	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GKZ67_RS07145	ENOG4105VJV	50s ribosomal protein L35
GKZ67_RS07150	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GKZ67_RS07170	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GKZ67_RS07175	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GKZ67_RS07180	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKZ67_RS07185	ENOG4105C3M	thioredoxin reductase
GKZ67_RS07190	ENOG4105E4C	Lytic transglycosylase catalytic
GKZ67_RS07200	ENOG4107W19	lmbE family
GKZ67_RS07205	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GKZ67_RS07210	ENOG4105BZU	Histidine kinase
GKZ67_RS07260	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GKZ67_RS07265	ENOG4106UW1	Major Facilitator superfamily
GKZ67_RS07270	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GKZ67_RS07275	ENOG4105ETE	Transcriptional regulator (LacI family
GKZ67_RS07285	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GKZ67_RS07330	ENOG4108Z12	YiaAB two helix domain-containing protein
GKZ67_RS07370	ENOG4108IJ8	ABC transporter
GKZ67_RS07405	ENOG4109015	Biopolymer transport protein exbD tolR
GKZ67_RS07420	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GKZ67_RS07430	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GKZ67_RS07500	ENOG4105CPC	Aldo Keto reductase
GKZ67_RS07505	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GKZ67_RS07525	ENOG4105C79	DNA protecting protein DprA
GKZ67_RS07580	ENOG4105DQ6	Transposase
GKZ67_RS07585	ENOG4108JNI	Alpha beta hydrolase
GKZ67_RS07620	ENOG4105VNH	ABC transporter solute-binding protein
GKZ67_RS07640	ENOG4107QN2	dihydrolipoyl dehydrogenase
GKZ67_RS07645	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GKZ67_RS07660	ENOG4105CI2	imidazolone-5-propionate hydrolase
GKZ67_RS07680	ENOG4108UJU	UPF0301 protein
GKZ67_RS07745	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GKZ67_RS07780	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GKZ67_RS07785	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GKZ67_RS07800	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GKZ67_RS07810	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GKZ67_RS07815	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GKZ67_RS07825	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GKZ67_RS07850	ENOG4105F95	Monooxygenase
GKZ67_RS07855	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GKZ67_RS07865	ENOG4105C7H	Helicase, RecD TraA family
GKZ67_RS07875	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GKZ67_RS07890	ENOG4105CSH	Transporter
GKZ67_RS07930	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
GKZ67_RS07940	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKZ67_RS07965	ENOG4108RWN	rrna methyltransferase
GKZ67_RS08000	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
GKZ67_RS08025	ENOG4105CH6	catalase
GKZ67_RS08030	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GKZ67_RS08080	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GKZ67_RS08095	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GKZ67_RS08105	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GKZ67_RS08110	ENOG4107SCA	Formamidase (EC 3.5.1.49)
GKZ67_RS08125	ENOG4105K4H	Nlp p60 protein
GKZ67_RS08170	ENOG4105CCU	oxidase (Subunit III)
GKZ67_RS08185	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GKZ67_RS08205	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
GKZ67_RS08220	ENOG4105C93	Xylose Isomerase
GKZ67_RS08250	ENOG4105CHR	reductase
GKZ67_RS08255	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
GKZ67_RS08265	ENOG4105ETE	Transcriptional regulator (LacI family
GKZ67_RS08275	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GKZ67_RS08285	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GKZ67_RS08295	ENOG4105E4C	Lytic transglycosylase catalytic
GKZ67_RS08325	ENOG4105ER2	Ompa motb domain protein
GKZ67_RS08345	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GKZ67_RS08350	ENOG4105GR3	Histidine kinase
GKZ67_RS08385	ENOG4107QHQ	amino acid
GKZ67_RS08430	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKZ67_RS08490	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKZ67_RS08495	ENOG41086DT	Membrane protein of unknown function
GKZ67_RS08500	ENOG4105CYW	agmatinase
GKZ67_RS08515	ENOG4107YTP	response regulator receiver protein
GKZ67_RS08520	ENOG4108V3W	Chemotaxis protein, CheW
GKZ67_RS08525	ENOG4105C8Q	Methyl-accepting chemotaxis
GKZ67_RS08540	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
GKZ67_RS08550	ENOG4105DFA	alanine racemase domain protein
GKZ67_RS08560	ENOG4105EMU	Dehydrogenase
GKZ67_RS08570	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GKZ67_RS08575	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GKZ67_RS08580	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GKZ67_RS08585	ENOG41067XB	TonB family
GKZ67_RS08600	ENOG4108EV3	Bifunctional aspartate kinase II homoserine dehydrogenase II
GKZ67_RS08605	ENOG4105D3R	alkyl hydroperoxide reductase
GKZ67_RS08615	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GKZ67_RS08620	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GKZ67_RS08630	ENOG4107ZE5	PPIases accelerate the folding of proteins
GKZ67_RS08710	ENOG4105C1J	atp-dependent rna helicase
GKZ67_RS08785	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
GKZ67_RS08815	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
GKZ67_RS08820	ENOG4107SRH	Nad-dependent epimerase dehydratase
GKZ67_RS08825	ENOG4105CBX	hi0933 family
GKZ67_RS08905	ENOG4105D0M	Protease HtpX homolog
GKZ67_RS08950	ENOG4105D78	K07001 NTE family protein
GKZ67_RS08955	ENOG4105C8F	Beta-lactamase domain protein
GKZ67_RS08960	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GKZ67_RS09010	ENOG4107AQZ	Membrane
GKZ67_RS09015	ENOG4105CN1	protease
GKZ67_RS09025	ENOG4105CRK	lysyL-tRNA synthetase
GKZ67_RS09035	ENOG4105C1J	atp-dependent rna helicase
GKZ67_RS09040	ENOG4105VEQ	Cold shock protein
GKZ67_RS09075	ENOG4108JYZ	YitT family
GKZ67_RS09080	ENOG4105QVC	MOSC domain-containing protein
GKZ67_RS09095	ENOG4105ZMH	deoxynucleoside kinase
GKZ67_RS09110	ENOG4108HPG	-acetyltransferase
GKZ67_RS09145	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GKZ67_RS09160	ENOG4105C9K	Endothelin-converting enzyme 1
GKZ67_RS09165	ENOG4105C9K	Endothelin-converting enzyme 1
GKZ67_RS09170	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GKZ67_RS09175	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GKZ67_RS09200	ENOG41080C8	DUF218 domain
GKZ67_RS09255	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GKZ67_RS09265	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GKZ67_RS09280	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GKZ67_RS09285	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GKZ67_RS09295	ENOG4108Z3N	Transcriptional regulator
GKZ67_RS09305	ENOG41085D1	50S ribosomal protein L32
GKZ67_RS09315	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GKZ67_RS09320	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GKZ67_RS09330	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GKZ67_RS09375	ENOG4105C5E	polysaccharide biosynthesis protein
GKZ67_RS09390	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKZ67_RS09400	ENOG4105CHR	reductase
GKZ67_RS09405	ENOG4107TY6	Acylneuraminate cytidylyltransferase
GKZ67_RS09420	ENOG4105D2T	synthase
GKZ67_RS09455	ENOG4105CUB	amino acid
GKZ67_RS09475	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKZ67_RS09500	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GKZ67_RS09510	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GKZ67_RS09520	ENOG41089BK	Glutamine amido-transferase
GKZ67_RS09545	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GKZ67_RS09555	ENOG4107S9R	deoxycytidine triphosphate deaminase
GKZ67_RS09570	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GKZ67_RS09585	ENOG4105C3G	gtp-binding protein
GKZ67_RS09635	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GKZ67_RS09645	ENOG4105CVJ	phosphoglycerate mutase
GKZ67_RS09650	ENOG4105KA0	thioesterase Superfamily protein
GKZ67_RS09660	ENOG4105CN9	Peptidase m42 family protein
GKZ67_RS09670	ENOG4108IPT	Naphthoate synthase
GKZ67_RS09690	ENOG4105CEY	Amp-dependent synthetase and ligase
GKZ67_RS09725	ENOG4108HRK	Histidine kinase
GKZ67_RS09730	ENOG4108VAC	response regulator
GKZ67_RS09740	ENOG4108NEV	two component transcriptional regulator, LytTR family
GKZ67_RS09745	ENOG4108HRK	Histidine kinase
GKZ67_RS09760	ENOG4105C27	TonB-dependent Receptor Plug
GKZ67_RS09795	ENOG4107QN2	dihydrolipoyl dehydrogenase
GKZ67_RS09930	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GKZ67_RS09965	ENOG4105HFZ	Membrane
GKZ67_RS09975	ENOG4107RJ1	sodium solute
GKZ67_RS09985	ENOG4105BZ1	(ABC) transporter
GKZ67_RS10010	ENOG4108Z9K	Osmotically inducible protein
GKZ67_RS10045	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKZ67_RS10050	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GKZ67_RS10075	ENOG4105E53	ec 3.2.1.28
GKZ67_RS10085	ENOG4105D4A	Cell wall formation (By similarity)
GKZ67_RS10100	ENOG4105BZU	Histidine kinase
GKZ67_RS10105	ENOG4105BZU	Histidine kinase
GKZ67_RS10110	ENOG4105BZU	Histidine kinase
GKZ67_RS10115	ENOG4105BZU	Histidine kinase
GKZ67_RS10130	ENOG4105C98	muts2 protein
GKZ67_RS10160	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GKZ67_RS10195	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GKZ67_RS10200	ENOG4108ZVT	methylmalonyl-coA epimerase
GKZ67_RS10210	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GKZ67_RS10220	ENOG4105BZU	Histidine kinase
GKZ67_RS10225	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GKZ67_RS10240	ENOG4108UJV	acyl-CoA thioesterase i
GKZ67_RS10245	ENOG4108I0Y	(ABC) transporter
GKZ67_RS10255	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GKZ67_RS10270	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GKZ67_RS10305	ENOG4107FW0	short-chain dehydrogenase reductase
GKZ67_RS10325	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GKZ67_RS10360	ENOG4105CJQ	hydrolase, family 31
GKZ67_RS10365	ENOG4105CJQ	hydrolase, family 31
GKZ67_RS10405	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GKZ67_RS10415	ENOG4107RH8	nuclease SbcCD subunit D
GKZ67_RS10430	ENOG4105EYH	Exonuclease
GKZ67_RS10435	ENOG4105EYH	Exonuclease
GKZ67_RS10520	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GKZ67_RS10555	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GKZ67_RS10565	ENOG4105BZ1	(ABC) transporter
GKZ67_RS10650	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GKZ67_RS10675	ENOG4105DUM	transcriptional regulator, lysR family
GKZ67_RS10740	ENOG4108IG5	Transcriptional regulator
GKZ67_RS10805	ENOG4105DQ6	Transposase
GKZ67_RS10820	ENOG4105CMM	transposase
GKZ67_RS10830	ENOG410836F	Transposase
GKZ67_RS10930	ENOG4105BZA	Phosphoglycerate kinase
GKZ67_RS10955	ENOG41082J7	Rhodanese domain protein
GKZ67_RS10960	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKZ67_RS10965	ENOG4107Y2X	deaminase
GKZ67_RS10975	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKZ67_RS11000	ENOG4107QVM	von Willebrand factor, type A
GKZ67_RS11015	ENOG4105CHU	acetyl-coa acetyltransferase
GKZ67_RS11040	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKZ67_RS11045	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKZ67_RS11055	ENOG4105FDR	Membrane
GKZ67_RS11075	ENOG41077A9	carbonic anhydrase
GKZ67_RS11100	ENOG4105ETX	regulatoR
GKZ67_RS11120	ENOG4105ERH	Fumarylacetoacetate hydrolase
GKZ67_RS11150	ENOG4105CHR	reductase
GKZ67_RS11180	ENOG4105CTX	dehydratase
GKZ67_RS11185	ENOG4105D2H	Uronic isomerase
GKZ67_RS11215	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GKZ67_RS11265	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GKZ67_RS11280	ENOG4105C5H	ABC transporter
GKZ67_RS11325	ENOG4108W6C	Dehydrogenase
GKZ67_RS11345	ENOG4105CNM	Receptor
GKZ67_RS11350	ENOG4105EJ9	Membrane
GKZ67_RS11360	ENOG4105DFU	Cell wall formation (By similarity)
GKZ67_RS11380	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GKZ67_RS11385	ENOG4105DR5	peptidase
GKZ67_RS11395	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKZ67_RS11435	ENOG4105CFG	Acts as a chaperone (By similarity)
GKZ67_RS11455	ENOG4105CD8	aminopeptidase N
GKZ67_RS11480	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
GKZ67_RS11485	ENOG4105CH7	arginosuccinase
GKZ67_RS11495	ENOG4107T6X	nag kinase
GKZ67_RS11505	ENOG4105CDH	Citrulline--aspartate ligase
GKZ67_RS11510	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GKZ67_RS11535	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GKZ67_RS11575	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GKZ67_RS11600	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GKZ67_RS11645	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GKZ67_RS11700	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GKZ67_RS11715	ENOG4105C31	Tryptophanyl-tRNA synthetase
GKZ67_RS11760	ENOG4105HHA	aminodeoxychorismate lyase
GKZ67_RS11830	ENOG4105ED2	Beta-lactamase
GKZ67_RS11855	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GKZ67_RS11865	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GKZ67_RS11870	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GKZ67_RS11875	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GKZ67_RS11885	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GKZ67_RS11890	ENOG4105C8S	subunit m
GKZ67_RS11895	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKZ67_RS11950	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GKZ67_RS11980	ENOG4105C26	Dehydrogenase
GKZ67_RS11990	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GKZ67_RS12000	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GKZ67_RS12010	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GKZ67_RS12020	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GKZ67_RS12025	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GKZ67_RS12035	ENOG410635A	Membrane
GKZ67_RS12075	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GKZ67_RS12095	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GKZ67_RS12115	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GKZ67_RS12120	ENOG4105EYW	Ion transport protein
GKZ67_RS12130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GKZ67_RS12170	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GKZ67_RS12175	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GKZ67_RS12185	ENOG4105DQ5	transport system permease protein
GKZ67_RS12190	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GKZ67_RS12195	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GKZ67_RS12210	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GKZ67_RS12215	ENOG4105VG0	50S ribosomal protein l34
GKZ67_RS12250	ENOG4105C1J	atp-dependent rna helicase
GKZ67_RS12260	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GKZ67_RS12285	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GKZ67_RS12290	ENOG4105C0P	Mg chelatase subunit ChlI
GKZ67_RS12300	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GKZ67_RS12330	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GKZ67_RS12335	ENOG4107SJI	Dehydrogenase
GKZ67_RS12340	ENOG4105BZ8	glutamate synthase
GKZ67_RS12355	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
GKZ67_RS12360	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GKZ67_RS12365	ENOG4105C26	Dehydrogenase
GKZ67_RS12380	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GKZ67_RS12425	ENOG4105D7W	serine acetyltransferase
GKZ67_RS12440	ENOG4105DNZ	Alpha Beta Hydrolase
GKZ67_RS12450	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
GKZ67_RS12470	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GKZ67_RS12475	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GKZ67_RS12480	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GKZ67_RS12490	ENOG4105C4K	Nad synthetase
GKZ67_RS12505	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GKZ67_RS12545	ENOG4105C2C	drug resistance transporter, Bcr CflA
GKZ67_RS12565	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKZ67_RS12570	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKZ67_RS12575	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKZ67_RS12600	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GKZ67_RS12605	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GKZ67_RS12645	ENOG4108Z6B	deaminase
GKZ67_RS12655	ENOG4105EAA	nucleoside
GKZ67_RS12665	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GKZ67_RS12670	ENOG4105SFS	phosphoesterase RecJ domain protein
GKZ67_RS12675	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GKZ67_RS12685	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GKZ67_RS12700	ENOG4107T8J	thymidine kinase
GKZ67_RS12740	ENOG4105CNI	cell division protein FtsW
GKZ67_RS12750	ENOG4105CJN	penicillin-binding protein
GKZ67_RS12755	ENOG4105CKK	Glycosyl transferase, family 2
GKZ67_RS12840	ENOG4105K4H	Nlp p60 protein
GKZ67_RS12845	ENOG4105CQB	FAD linked oxidase domain protein
GKZ67_RS12850	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKZ67_RS12965	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GKZ67_RS12970	ENOG4105DPN	Oligoendopeptidase f
GKZ67_RS12975	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GKZ67_RS13005	ENOG4105EXC	Acyl-transferase
GKZ67_RS13010	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GKZ67_RS13035	ENOG4105E33	succinate dehydrogenase
GKZ67_RS13100	ENOG410662T	chitinase
GKZ67_RS13110	ENOG4105C27	TonB-dependent Receptor Plug
GKZ67_RS13125	ENOG4105E2D	ec 3.2.1.52
GKZ67_RS13135	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GKZ67_RS13140	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
GKZ67_RS13145	ENOG4105CHV	Transcription elongation factor NusA
GKZ67_RS13150	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GKZ67_RS13160	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GKZ67_RS13165	ENOG4105E39	Enoyl-CoA hydratase
GKZ67_RS13175	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GKZ67_RS13180	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GKZ67_RS13185	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKZ67_RS13190	ENOG4105K4H	Nlp p60 protein
GKZ67_RS13195	ENOG4105C6K	Malic enzyme
GKZ67_RS13200	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GKZ67_RS13215	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GKZ67_RS13235	ENOG4105DSJ	YicC domain protein
GKZ67_RS13240	ENOG4108KPZ	tonB-dependent Receptor
GKZ67_RS13260	ENOG4105EV9	Alpha Beta Hydrolase
GKZ67_RS13285	ENOG4105D3Q	Sugar transferase
GKZ67_RS13290	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GKZ67_RS13315	ENOG4105EMN	RNA polymerase sigma factor
GKZ67_RS13320	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GKZ67_RS13325	ENOG4105D64	Mechanosensitive ion channel
GKZ67_RS13335	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
GKZ67_RS13365	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKZ67_RS13375	ENOG4105C28	cystathionine
GKZ67_RS13380	ENOG41082VD	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GKZ67_RS13395	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKZ67_RS13405	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GKZ67_RS13410	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GKZ67_RS13425	ENOG4105E0X	reductase
GKZ67_RS13430	ENOG4105CI3	gtp-binding protein typa
GKZ67_RS13440	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKZ67_RS13445	ENOG4105BZU	Histidine kinase
GKZ67_RS13465	ENOG4105CSM	endonuclease III
GKZ67_RS13470	ENOG4107BJW	polysaccharide deacetylase
GKZ67_RS13475	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GKZ67_RS13480	ENOG4108M0I	Transcriptional regulator
GKZ67_RS13485	ENOG4108MJ5	VirK protein
GKZ67_RS13525	ENOG4105BZU	Histidine kinase
GKZ67_RS13545	ENOG4105D44	asparaginase
GKZ67_RS13560	ENOG4108Z9Z	response to DNA damage stimulus
GKZ67_RS13565	ENOG410836F	Transposase
GKZ67_RS13570	ENOG4105BZU	Histidine kinase
GKZ67_RS13585	ENOG4105CEY	Amp-dependent synthetase and ligase
GKZ67_RS13590	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GKZ67_RS13610	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GKZ67_RS13625	ENOG4105NWN	ApaG protein
GKZ67_RS13635	ENOG41068JE	domain protein
GKZ67_RS13640	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GKZ67_RS13650	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GKZ67_RS13660	ENOG4107RJ9	Cell division protein FtsX
GKZ67_RS13670	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GKZ67_RS13675	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GKZ67_RS13680	ENOG4105DTN	riboflavin biosynthesis protein ribF
GKZ67_RS13695	ENOG4107QP7	CoA-transferase subunit A
GKZ67_RS13715	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GKZ67_RS13750	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKZ67_RS13760	ENOG4105E2D	ec 3.2.1.52
GKZ67_RS13770	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GKZ67_RS13775	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
GKZ67_RS13900	ENOG4108HWS	Histidine kinase
GKZ67_RS13940	ENOG4107R3R	Cytochrome o ubiquinol oxidase subunit III
GKZ67_RS13955	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GKZ67_RS13960	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GKZ67_RS13985	ENOG4107SFQ	iron-sulfur binding
GKZ67_RS13995	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
GKZ67_RS14000	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GKZ67_RS14005	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GKZ67_RS14020	ENOG4105C7Z	Conserved Protein
GKZ67_RS14025	ENOG4105C25	Primosomal protein n'
GKZ67_RS14040	ENOG4107RAQ	aminopeptidase
GKZ67_RS14045	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GKZ67_RS14070	ENOG4105C0B	DNA polymerase III (alpha subunit)
GKZ67_RS14085	ENOG4105K63	Thioredoxin
GKZ67_RS14105	ENOG4108VVK	transcriptional Regulator, AsnC
GKZ67_RS14115	ENOG4105C37	(CBS) domain
GKZ67_RS14125	ENOG4105YB8	TM2 domain containing protein
GKZ67_RS14160	ENOG4105CDV	Ompa motb domain protein
GKZ67_RS14165	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GKZ67_RS14270	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GKZ67_RS14275	ENOG4105CAY	ferredoxin--nadp reductase
GKZ67_RS14320	ENOG4108VCT	Sulfite exporter TauE/SafE
GKZ67_RS14325	ENOG4105NQN	cytochrome C
GKZ67_RS14335	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GKZ67_RS14370	ENOG4105VEQ	Cold shock protein
GKZ67_RS14380	ENOG4108ZIT	Ferredoxin, 2FE-2S
GKZ67_RS14405	ENOG4105BZU	Histidine kinase
GKZ67_RS14410	ENOG4105DY9	regulatoR
GKZ67_RS14415	ENOG4105DY9	regulatoR
GKZ67_RS14430	ENOG41060IM	Heme exporter protein
GKZ67_RS14455	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GKZ67_RS14460	ENOG4105C5X	domain protein
GKZ67_RS14465	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GKZ67_RS14560	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GKZ67_RS14570	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GKZ67_RS14585	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GKZ67_RS14615	ENOG4105CE1	Ferrous iron transport protein b
GKZ67_RS14640	ENOG4105F6J	Alpha beta hydrolase fold
GKZ67_RS14650	ENOG4108ZG0	Ompa motb domain protein
GKZ67_RS14655	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GKZ67_RS14660	ENOG4105E1F	short-chain dehydrogenase reductase
GKZ67_RS14700	ENOG4105Y3E	Modulates RecA activity (By similarity)
GKZ67_RS14730	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKZ67_RS14745	ENOG4105CKK	Glycosyl transferase, family 2
GKZ67_RS14750	ENOG4105C2X	Arabinose 5-phosphate isomerase
GKZ67_RS14755	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GKZ67_RS14765	ENOG4108Y6J	UPF0403 protein
GKZ67_RS14795	ENOG4105BZU	Histidine kinase
GKZ67_RS14805	ENOG4105DY9	regulatoR
GKZ67_RS14840	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKZ67_RS14865	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GKZ67_RS14890	ENOG41081WG	50s ribosomal protein l31
GKZ67_RS14900	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GKZ67_RS14905	ENOG4105DBI	uridine monophosphokinase
GKZ67_RS14925	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GKZ67_RS15005	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GKZ67_RS15035	ENOG4108IJ6	ABC transporter
GKZ67_RS15040	ENOG4105E0C	molybdate abc transporter
GKZ67_RS15050	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GKZ67_RS15075	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GKZ67_RS15085	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
GKZ67_RS15095	ENOG4105E1F	short-chain dehydrogenase reductase
GKZ67_RS15125	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GKZ67_RS15135	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKZ67_RS15165	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKZ67_RS15170	ENOG4105BZU	Histidine kinase
GKZ67_RS15180	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GKZ67_RS15185	ENOG4108UJD	30S ribosomal protein S9
GKZ67_RS15190	ENOG4105CE9	30S ribosomal protein S2
GKZ67_RS15195	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GKZ67_RS15270	ENOG41067XB	TonB family
GKZ67_RS15310	ENOG4108ZT0	50S ribosomal protein l17
GKZ67_RS15315	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKZ67_RS15320	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GKZ67_RS15325	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GKZ67_RS15330	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKZ67_RS15335	ENOG410864M	50S ribosomal protein L36
GKZ67_RS15340	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GKZ67_RS15355	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GKZ67_RS15365	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GKZ67_RS15370	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GKZ67_RS15375	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GKZ67_RS15385	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GKZ67_RS15395	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GKZ67_RS15400	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GKZ67_RS15405	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GKZ67_RS15410	ENOG4108628	50s ribosomal protein l29
GKZ67_RS15415	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GKZ67_RS15420	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GKZ67_RS15430	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GKZ67_RS15435	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKZ67_RS15440	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GKZ67_RS15445	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GKZ67_RS15450	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GKZ67_RS15460	ENOG4107XZA	Glycosyl transferase family 2
GKZ67_RS15465	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GKZ67_RS15470	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GKZ67_RS15475	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GKZ67_RS15480	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GKZ67_RS15490	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GKZ67_RS15500	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GKZ67_RS15505	ENOG4107VNI	ribosomal protein l10
GKZ67_RS15510	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GKZ67_RS15515	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GKZ67_RS15570	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GKZ67_RS15575	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GKZ67_RS15580	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GKZ67_RS15585	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GKZ67_RS15595	ENOG4105EMN	RNA polymerase sigma factor
GKZ67_RS15605	ENOG4106WTF	Glycosyl transferase, family 2
GKZ67_RS15615	ENOG4105EMU	Dehydrogenase
GKZ67_RS15635	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GKZ67_RS15645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKZ67_RS15650	ENOG41083X6	30S ribosomal protein S21
GKZ67_RS15655	ENOG4105C1G	acyl-Coa dehydrogenase
GKZ67_RS15685	ENOG41061P3	phosphosulfolactate synthase
GKZ67_RS15710	ENOG4105FFC	UPF0187 protein
GKZ67_RS15715	ENOG4105DQR	SNARE associated Golgi
GKZ67_RS15720	ENOG4105E2X	shikimate dehydrogenase
GKZ67_RS15735	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GKZ67_RS15745	ENOG4105D78	K07001 NTE family protein
GKZ67_RS15805	ENOG4108RAV	Conserved protein
GKZ67_RS15815	ENOG4108IUK	alpha amylase, catalytic
GKZ67_RS15835	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKZ67_RS15840	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GKZ67_RS15845	ENOG4105CN1	protease
GKZ67_RS15865	ENOG4107FW0	short-chain dehydrogenase reductase
GKZ67_RS15875	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
GKZ67_RS15885	ENOG4107QI1	Mate efflux family protein
GKZ67_RS15905	ENOG4107S1W	4-alpha-glucanotransferase
GKZ67_RS15910	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GKZ67_RS15955	ENOG4108ZAF	Molybdopterin
GKZ67_RS15965	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GKZ67_RS15985	ENOG4105F4R	Transcriptional regulator mode
GKZ67_RS15990	ENOG4105C3M	thioredoxin reductase
GKZ67_RS16020	ENOG4107QKV	phosphomannomutase
GKZ67_RS16075	ENOG4105C34	Pseudouridine synthase
GKZ67_RS16090	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GKZ67_RS16095	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GKZ67_RS16110	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GKZ67_RS16130	ENOG4106HB6	Alpha beta hydrolase
GKZ67_RS16135	ENOG4105DDQ	anthranilate synthase
GKZ67_RS16150	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GKZ67_RS16195	ENOG4108JUA	Transcriptional regulator
GKZ67_RS16210	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GKZ67_RS16215	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKZ67_RS16235	ENOG4105ECY	inositol monophosphatase
GKZ67_RS16275	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GKZ67_RS16280	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GKZ67_RS16285	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GKZ67_RS16305	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GKZ67_RS16315	ENOG4105C0D	helicase
GKZ67_RS16365	ENOG4108W0I	acetyltransferase
GKZ67_RS16435	ENOG4105DTD	Dehydrogenase
GKZ67_RS16460	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GKZ67_RS16475	ENOG4105CS2	ec 3.2.1.21
GKZ67_RS16530	ENOG4108J2R	molybdopterin oxidoreductase
GKZ67_RS16535	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GKZ67_RS16545	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GKZ67_RS16560	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GKZ67_RS16565	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GKZ67_RS16580	ENOG4105CHM	Aminotransferase
GKZ67_RS16595	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GKZ67_RS16605	ENOG4105DF6	Fe-S oxidoreductase
GKZ67_RS16615	ENOG4105DF6	Fe-S oxidoreductase
GKZ67_RS16625	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GKZ67_RS16645	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
GKZ67_RS16655	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
GKZ67_RS16665	ENOG4105KNE	Phosphatidate cytidylyltransferase
GKZ67_RS16695	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GKZ67_RS16710	ENOG4105E66	phosphoriboisomerase A
GKZ67_RS16730	ENOG4105P8Q	Curli production assembly transport component CsgG
GKZ67_RS16760	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GKZ67_RS16780	ENOG4105BZU	Histidine kinase
GKZ67_RS16785	ENOG4108NEV	two component transcriptional regulator, LytTR family
GKZ67_RS16790	ENOG4105CUB	amino acid
GKZ67_RS16830	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
GKZ67_RS16835	ENOG4108ZGC	gaf domain protein
GKZ67_RS16840	ENOG4105D64	Mechanosensitive ion channel
GKZ67_RS16850	ENOG41080HT	Transcriptional regulator, arsr family
GKZ67_RS16855	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GKZ67_RS16865	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GKZ67_RS16870	ENOG4108IAJ	Nad-dependent epimerase dehydratase
GKZ67_RS16880	ENOG4105CMR	udp-glucose 4-epimerase
GKZ67_RS16890	ENOG4105J5G	Transferase hexapeptide repeat containing protein
GKZ67_RS16935	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
GKZ67_RS16955	ENOG4107VXZ	Hydrolase
GKZ67_RS16965	ENOG4105F0N	pyrophosphate phospho-hydrolase
GKZ67_RS16975	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GKZ67_RS16985	ENOG4105E0X	reductase
GKZ67_RS17020	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GKZ67_RS17025	ENOG4105KBX	Transcriptional regulator, TetR family
GKZ67_RS17045	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GKZ67_RS17055	ENOG4108QBX	(LipO)protein
GKZ67_RS17065	ENOG4105CHR	reductase
GKZ67_RS17080	ENOG4105C3M	thioredoxin reductase
GKZ67_RS17095	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GKZ67_RS17155	ENOG4105DAP	Nicotinate phosphoribosyltransferase
GKZ67_RS17175	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GKZ67_RS17185	ENOG4107QNG	Phosphoribosylglycinamide synthetase
GKZ67_RS17210	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GKZ67_RS17215	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GKZ67_RS17290	ENOG4105F0N	pyrophosphate phospho-hydrolase
GKZ67_RS17305	ENOG4105C5H	ABC transporter
GKZ67_RS17325	ENOG4105DIK	(ABC) transporter
GKZ67_RS17330	ENOG4107RMN	lycopene cyclase
GKZ67_RS17340	ENOG4108ZG0	Ompa motb domain protein
GKZ67_RS17350	ENOG4105E6M	Sulphatase-modifying factor protein
GKZ67_RS17355	ENOG4105MJ2	Competence protein
GKZ67_RS17370	ENOG4105CGK	Exodeoxyribonuclease III
GKZ67_RS17380	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GKZ67_RS17390	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
GKZ67_RS17490	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GKZ67_RS17540	ENOG4105VDW	Csbd family
GKZ67_RS17545	ENOG4105DGU	Histone deacetylase
GKZ67_RS17565	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GKZ67_RS17580	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GKZ67_RS17585	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GKZ67_RS17595	ENOG4108V0P	LemA family
GKZ67_RS17635	ENOG410836F	Transposase
GKZ67_RS17650	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GKZ67_RS17675	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GKZ67_RS17680	ENOG4105FE9	pseudouridine synthase
GKZ67_RS17690	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GKZ67_RS17700	ENOG4107R0V	Pyruvate dehydrogenase
GKZ67_RS17705	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GKZ67_RS17720	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKZ67_RS17750	ENOG4108JQ6	ABC transporter
GKZ67_RS17755	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GKZ67_RS17760	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GKZ67_RS17780	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GKZ67_RS17785	ENOG4105CJ3	phosphate transporter
GKZ67_RS17830	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GKZ67_RS17880	ENOG4105C3F	Signal peptidase i
GKZ67_RS17885	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GKZ67_RS17890	ENOG4105BZU	Histidine kinase
GKZ67_RS17905	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GKZ67_RS17915	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GKZ67_RS17930	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GKZ67_RS17935	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKZ67_RS17975	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GKZ67_RS17995	ENOG4105EXW	epimerase dehydratase
GKZ67_RS18030	ENOG4107S2Z	UPF0761 membrane protein
GKZ67_RS18045	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKZ67_RS18080	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GKZ67_RS18100	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GKZ67_RS18110	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GKZ67_RS18140	ENOG4107RNH	Outer membrane receptor FepA
GKZ67_RS18185	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GKZ67_RS18190	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GKZ67_RS18210	ENOG4105C2M	dna polymerase I
GKZ67_RS18245	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
GKZ67_RS18250	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKZ67_RS18275	ENOG4105C1G	acyl-Coa dehydrogenase
GKZ67_RS18280	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GKZ67_RS18295	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GKZ67_RS18335	ENOG4107RGD	Major Facilitator superfamily
GKZ67_RS18350	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GKZ67_RS18415	ENOG4105C9Q	fumarate hydratase class II
GKZ67_RS18425	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
GKZ67_RS18485	ENOG4105C7S	Dehydrogenase
GKZ67_RS18490	ENOG4105IJJ	transcriptional regulator, crp fnr family
GKZ67_RS18515	ENOG4107QN2	dihydrolipoyl dehydrogenase
GKZ67_RS18535	ENOG4105VEQ	Cold shock protein
GKZ67_RS18585	ENOG4108Z0Z	intracellular protease Pfpi family
GKZ67_RS18630	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
GKZ67_RS18655	ENOG4108IUZ	ABC transporter
GKZ67_RS18675	ENOG4105CP2	von willebrand factor, type a
GKZ67_RS18695	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GKZ67_RS18705	ENOG4105D52	delta-aminolevulinic acid dehydratase
GKZ67_RS18720	ENOG4105C8Y	Acetylornithine aminotransferase
GKZ67_RS18725	ENOG4105KME	endoribonuclease L-psp
GKZ67_RS18735	ENOG4105KDC	50s ribosomal protein l28
GKZ67_RS18740	ENOG41083ND	50S ribosomal protein L33
GKZ67_RS18750	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKZ67_RS18835	ENOG4107Z6X	Transcriptional regulator
GKZ67_RS18870	ENOG4105BZU	Histidine kinase
GKZ67_RS18880	ENOG4105E4I	Glycoside hydrolase family 28
GKZ67_RS18895	ENOG4108HHA	Transketolase
GKZ67_RS18900	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GKZ67_RS18910	ENOG4108R85	Short chain dehydrogenase
GKZ67_RS18915	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GKZ67_RS18920	ENOG4105D2T	synthase
GKZ67_RS18945	ENOG4108YYC	ycei family
GKZ67_RS18960	ENOG4105CEP	NADH dehydrogenase
GKZ67_RS18970	ENOG4105D64	Mechanosensitive ion channel
GKZ67_RS19000	ENOG4108FN7	Aldo keto reductase
GKZ67_RS19005	ENOG4107ZXU	DSBA oxidoreductase
GKZ67_RS19020	ENOG4107RNH	Outer membrane receptor FepA
GKZ67_RS19030	ENOG4108JA2	transcriptioN-repair coupling factor
GKZ67_RS19055	ENOG4108VPT	UPF0234 protein
GKZ67_RS19060	ENOG4105EE5	Membrane protein terC
GKZ67_RS19075	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKZ67_RS19080	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GKZ67_RS19085	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GKZ67_RS19100	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GKZ67_RS19105	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GKZ67_RS19110	ENOG4105WH1	Two component transcriptional regulator luxr family
GKZ67_RS19155	ENOG41082RQ	UPF0102 protein
GKZ67_RS19160	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GKZ67_RS19170	ENOG4105ESV	Glycosyl transferase, family 4
GKZ67_RS19190	ENOG4105E6M	Sulphatase-modifying factor protein
GKZ67_RS19210	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GKZ67_RS19215	ENOG4108JQC	penicillin-binding protein 1A
GKZ67_RS19235	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GKZ67_RS19240	ENOG4105VHG	atp synthase
GKZ67_RS19245	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GKZ67_RS19260	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GKZ67_RS19320	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GKZ67_RS19325	ENOG4105BZ1	(ABC) transporter
GKZ67_RS19365	ENOG4105BZ1	(ABC) transporter
GKZ67_RS19375	ENOG4107R6T	Involved in the transcription termination process (By similarity)
GKZ67_RS19385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GKZ67_RS19405	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GKZ67_RS19480	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GKZ67_RS19510	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKZ67_RS19515	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKZ67_RS19565	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GKZ67_RS19630	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GKZ67_RS19680	ENOG4107RE3	peptidase, S41
GKZ67_RS19725	ENOG4105SYT	Methylenetetrahydrofolate reductase
GKZ67_RS19750	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GKZ67_RS19765	ENOG4105ETE	Transcriptional regulator (LacI family
GKZ67_RS19795	ENOG4105DMW	Dehydrogenase reductase
GKZ67_RS19800	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GKZ67_RS19805	ENOG4105DSG	hydrolase family 43
GKZ67_RS19820	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GKZ67_RS19840	ENOG4109066	lysm domain bon superfamily protein
GKZ67_RS19900	ENOG4107S5I	aldo keto reductase
GKZ67_RS19910	ENOG4105EUB	pirin domain protein
GKZ67_RS19925	ENOG4107TJ9	Cytochrome
GKZ67_RS19940	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GKZ67_RS20010	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GKZ67_RS20075	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GKZ67_RS20100	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GKZ67_RS20155	ENOG4105BZS	acriflavin resistance protein
GKZ67_RS20210	ENOG4105C2J	ABC transporter
GKZ67_RS20220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKZ67_RS20240	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GKZ67_RS20245	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GKZ67_RS20250	ENOG4107RSM	transcriptional regulator
GKZ67_RS20275	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GKZ67_RS20285	ENOG4105CFH	Aspartokinase
GKZ67_RS20290	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GKZ67_RS20305	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GKZ67_RS20360	ENOG4105K6T	rare lipoprotein A
GKZ67_RS20370	ENOG4108UQ1	hydrolase, family 25
GKZ67_RS20375	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GKZ67_RS20415	ENOG4105K46	50S ribosomal protein l27
GKZ67_RS20420	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GKZ67_RS20435	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GKZ67_RS20505	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
GKZ67_RS20590	ENOG4105DUX	Transporter
GKZ67_RS20600	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
GKZ67_RS20680	ENOG4108C33	Resolvase
GKZ67_RS20730	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GKZ67_RS20735	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GKZ67_RS21190	ENOG4107QKA	exodeoxyribonuclease V beta
GKZ67_RS21255	ENOG4105DQ6	Transposase
GKZ67_RS21310	ENOG41067QW	Transcriptional regulator
GKZ67_RS21410	ENOG4105BZU	Histidine kinase
GKZ67_RS21580	ENOG4107QJE	Chromosome Partitioning Protein
GKZ67_RS21605	ENOG4108C33	Resolvase
GKZ67_RS21650	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GKZ67_RS21745	ENOG4105DQ6	Transposase
GKZ67_RS21790	ENOG41080HI	glycine oxidase
GKZ67_RS21795	ENOG4107TTQ	Alpha beta hydrolase fold
GKZ67_RS21865	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GKZ67_RS21925	ENOG410836F	Transposase
GKZ67_RS22040	ENOG4105DTT	CRISPR-associated helicase, cas3
GKZ67_RS22055	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GKZ67_RS22065	ENOG4108C33	Resolvase
GKZ67_RS22075	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
GKZ67_RS22100	ENOG4108C33	Resolvase
GKZ67_RS22230	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GKZ67_RS22250	ENOG4105CMM	transposase
GKZ67_RS22290	ENOG410836F	Transposase