locus-tag	class	description
GUY19_RS00025	ENOG4105C3G	gtp-binding protein
GUY19_RS00065	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GUY19_RS00095	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GUY19_RS00125	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
GUY19_RS00145	ENOG4105DFA	alanine racemase domain protein
GUY19_RS00170	ENOG4108Z7R	Chaperone CsaA
GUY19_RS00180	ENOG4107QI1	Mate efflux family protein
GUY19_RS00185	ENOG41067HS	methyltransferase
GUY19_RS00190	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
GUY19_RS00230	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GUY19_RS00255	ENOG4105BZU	Histidine kinase
GUY19_RS00325	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GUY19_RS00390	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
GUY19_RS00405	ENOG4105C2F	Histidine kinase
GUY19_RS00410	ENOG4108NEV	two component transcriptional regulator, LytTR family
GUY19_RS00415	ENOG4105C5H	ABC transporter
GUY19_RS00430	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GUY19_RS00445	ENOG4105P8Q	Curli production assembly transport component CsgG
GUY19_RS00525	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GUY19_RS00545	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GUY19_RS00550	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GUY19_RS00585	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GUY19_RS00595	ENOG4105EHZ	conserved protein UCP016719
GUY19_RS00610	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GUY19_RS00615	ENOG4105DPN	Oligoendopeptidase f
GUY19_RS00630	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
GUY19_RS00645	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
GUY19_RS00650	ENOG4108IG5	Transcriptional regulator
GUY19_RS00660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GUY19_RS00675	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GUY19_RS00690	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GUY19_RS00715	ENOG4107Z60	histidine triad (HIT) protein
GUY19_RS00880	ENOG4108C33	Resolvase
GUY19_RS00890	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS00925	ENOG4105CKK	Glycosyl transferase, family 2
GUY19_RS01010	ENOG4105BZU	Histidine kinase
GUY19_RS01020	ENOG4105BZU	Histidine kinase
GUY19_RS01040	ENOG4105CD8	aminopeptidase N
GUY19_RS01045	ENOG4105CJ1	ABC, transporter
GUY19_RS01055	ENOG4108HRK	Histidine kinase
GUY19_RS01060	ENOG4105DY9	regulatoR
GUY19_RS01065	ENOG4105EEM	helicase
GUY19_RS01095	ENOG4105CJ1	ABC, transporter
GUY19_RS01125	ENOG4105C59	p-type ATPase
GUY19_RS01140	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GUY19_RS01150	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GUY19_RS01155	ENOG4105C58	cytochrome c oxidase accessory protein ccog
GUY19_RS01175	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GUY19_RS01180	ENOG4105IJJ	transcriptional regulator, crp fnr family
GUY19_RS01195	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GUY19_RS01200	ENOG4105C93	Xylose Isomerase
GUY19_RS01205	ENOG4105CMG	Carbohydrate kinase
GUY19_RS01210	ENOG4105C59	p-type ATPase
GUY19_RS01260	ENOG4105CU9	asparagine synthetase A
GUY19_RS01295	ENOG4105BZU	Histidine kinase
GUY19_RS01315	ENOG4105CNG	UPF0061 protein
GUY19_RS01325	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
GUY19_RS01330	ENOG4105DGW	oligopeptidase A
GUY19_RS01335	ENOG4107TPY	serine threonine protein kinase
GUY19_RS01380	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
GUY19_RS01385	ENOG4105BZU	Histidine kinase
GUY19_RS01400	ENOG4105CHR	reductase
GUY19_RS01410	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GUY19_RS01420	ENOG4107QI1	Mate efflux family protein
GUY19_RS01450	ENOG4105DGU	Histone deacetylase
GUY19_RS01470	ENOG4105E0Y	RtcB Protein
GUY19_RS01475	ENOG4105E0Y	RtcB Protein
GUY19_RS01555	ENOG4105F23	Fibronectin-binding protein
GUY19_RS01570	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GUY19_RS01575	ENOG4108MGY	Histidine kinase
GUY19_RS01580	ENOG4105BZU	Histidine kinase
GUY19_RS01590	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GUY19_RS01595	ENOG4105CTQ	phosphohexokinase
GUY19_RS01645	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GUY19_RS01650	ENOG4108TF4	von Willebrand factor, type A
GUY19_RS01655	ENOG4108HHA	Transketolase
GUY19_RS01660	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GUY19_RS01670	ENOG4105DR5	peptidase
GUY19_RS01675	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GUY19_RS01695	ENOG4105DFU	Cell wall formation (By similarity)
GUY19_RS01700	ENOG4105CDU	Replicative dna helicase
GUY19_RS01710	ENOG4107RNH	Outer membrane receptor FepA
GUY19_RS01725	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GUY19_RS01755	ENOG41084YZ	Hydrolase
GUY19_RS01785	ENOG4108IJ8	ABC transporter
GUY19_RS01790	ENOG4105E90	ABC transporter
GUY19_RS01795	ENOG4108NEV	two component transcriptional regulator, LytTR family
GUY19_RS01800	ENOG4108HRK	Histidine kinase
GUY19_RS01805	ENOG4105DHU	Bile acid
GUY19_RS01815	ENOG4105DEN	Luciferase family
GUY19_RS01830	ENOG4105DTD	Dehydrogenase
GUY19_RS01835	ENOG4105MIR	Phenylalanine 4-monooxygenase
GUY19_RS01840	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GUY19_RS01865	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GUY19_RS01880	ENOG4105BZ1	(ABC) transporter
GUY19_RS01895	ENOG4105C7W	Xanthine dehydrogenase
GUY19_RS01900	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
GUY19_RS01905	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
GUY19_RS01920	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GUY19_RS01925	ENOG4108ZAF	Molybdopterin
GUY19_RS01935	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GUY19_RS01955	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
GUY19_RS01960	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
GUY19_RS01965	ENOG4105C7W	Xanthine dehydrogenase
GUY19_RS01980	ENOG4107P26	
GUY19_RS01990	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GUY19_RS01995	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
GUY19_RS02005	ENOG4105CBD	Diacylglycerol kinase
GUY19_RS02020	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GUY19_RS02040	ENOG4105C98	muts2 protein
GUY19_RS02075	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GUY19_RS02095	ENOG41067QW	Transcriptional regulator
GUY19_RS02135	ENOG4105C1J	atp-dependent rna helicase
GUY19_RS02160	ENOG4108KF3	Electron transport protein SCO1 SenC
GUY19_RS02180	ENOG4105CPC	Aldo Keto reductase
GUY19_RS02195	ENOG4105CBX	hi0933 family
GUY19_RS02210	ENOG4105EGS	Mechanosensitive ion channel
GUY19_RS02245	ENOG4108YYQ	gCN5-related N-acetyltransferase
GUY19_RS02260	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GUY19_RS02280	ENOG4105VEQ	Cold shock protein
GUY19_RS02285	ENOG4105C1J	atp-dependent rna helicase
GUY19_RS02300	ENOG4105CBX	hi0933 family
GUY19_RS02305	ENOG4108535	NAD dependent epimerase/dehydratase family
GUY19_RS02310	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
GUY19_RS02335	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GUY19_RS02340	ENOG4105CZH	peptidase
GUY19_RS02380	ENOG4105D44	asparaginase
GUY19_RS02390	ENOG4105CD8	aminopeptidase N
GUY19_RS02415	ENOG4105C1J	atp-dependent rna helicase
GUY19_RS02445	ENOG4107S1Q	Phosphatase
GUY19_RS02450	ENOG410756H	nucleotidyltransferase
GUY19_RS02475	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GUY19_RS02485	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GUY19_RS02505	ENOG4105C8F	Beta-lactamase domain protein
GUY19_RS02510	ENOG4105D78	K07001 NTE family protein
GUY19_RS02525	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GUY19_RS02545	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GUY19_RS02560	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
GUY19_RS02580	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GUY19_RS02585	ENOG4105DUX	Transporter
GUY19_RS02590	ENOG4105DUX	Transporter
GUY19_RS02595	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GUY19_RS02600	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GUY19_RS02620	ENOG4107WT5	transcriptional regulator (NifA
GUY19_RS02625	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GUY19_RS02630	ENOG4105CRQ	synthase (Component I)
GUY19_RS02645	ENOG4105EGD	dinuclear metal center protein, YbgI family
GUY19_RS02655	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GUY19_RS02670	ENOG4105CNT	hydrolase family 2
GUY19_RS02685	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GUY19_RS02695	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GUY19_RS02735	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GUY19_RS02755	ENOG4107YBY	Hydrolase
GUY19_RS02775	ENOG4105MSB	protein, conserved in bacteria
GUY19_RS02780	ENOG4108Z40	Transcriptional regulator
GUY19_RS02785	ENOG4108RYK	Nad-dependent epimerase dehydratase
GUY19_RS02790	ENOG4105C8T	Leucyl-tRNA synthetase
GUY19_RS02810	ENOG4108ZIP	spheroidene monooxygenase
GUY19_RS02825	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GUY19_RS02890	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GUY19_RS02925	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GUY19_RS02945	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GUY19_RS02950	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GUY19_RS02975	ENOG4108S4H	thioesterase Superfamily protein
GUY19_RS02985	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GUY19_RS02995	ENOG4108R6K	riboflavin synthase, subunit alpha
GUY19_RS03015	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GUY19_RS03020	ENOG4105CPP	Dehydrogenase, E1 component
GUY19_RS03065	ENOG4105DZ0	fad dependent oxidoreductase
GUY19_RS03075	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
GUY19_RS03095	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GUY19_RS03120	ENOG4106UW1	Major Facilitator superfamily
GUY19_RS03125	ENOG4105CH6	catalase
GUY19_RS03135	ENOG4108Z03	MAF-like protein
GUY19_RS03145	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GUY19_RS03150	ENOG4108UJU	UPF0301 protein
GUY19_RS03185	ENOG4108IJ6	ABC transporter
GUY19_RS03195	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GUY19_RS03205	ENOG4105ES5	Histidine kinase
GUY19_RS03210	ENOG4105BZU	Histidine kinase
GUY19_RS03215	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GUY19_RS03245	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GUY19_RS03385	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GUY19_RS03390	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GUY19_RS03395	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GUY19_RS03400	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GUY19_RS03405	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GUY19_RS03410	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GUY19_RS03415	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GUY19_RS03420	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GUY19_RS03435	ENOG4105DJV	ribulose-phosphate 3-epimerase
GUY19_RS03445	ENOG41090GG	peptidase S8 and S53, subtilisin, kexin, sedolisin
GUY19_RS03455	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GUY19_RS03470	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GUY19_RS03485	ENOG4109015	Biopolymer transport protein exbD tolR
GUY19_RS03530	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GUY19_RS03540	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GUY19_RS03545	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GUY19_RS03560	ENOG4105E4C	Lytic transglycosylase catalytic
GUY19_RS03565	ENOG4105C3M	thioredoxin reductase
GUY19_RS03570	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GUY19_RS03575	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GUY19_RS03580	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GUY19_RS03605	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GUY19_RS03610	ENOG4105VJV	50s ribosomal protein L35
GUY19_RS03615	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GUY19_RS03620	ENOG4105C22	threonyL-tRNA synthetase
GUY19_RS03630	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GUY19_RS03640	ENOG4105DF5	DNA topoisomerase IV, subunit A
GUY19_RS03655	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
GUY19_RS03660	ENOG4105C02	permease
GUY19_RS03670	ENOG4105DVT	helicase
GUY19_RS03695	ENOG4105D0M	Protease HtpX homolog
GUY19_RS03715	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GUY19_RS03730	ENOG4107TE5	Lipid kinase
GUY19_RS03765	ENOG4105C5H	ABC transporter
GUY19_RS03780	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GUY19_RS03790	ENOG4105D44	asparaginase
GUY19_RS03800	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GUY19_RS03805	ENOG4107EF8	Glycosyl transferase (Group 1
GUY19_RS03810	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GUY19_RS03820	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GUY19_RS03845	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GUY19_RS03850	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GUY19_RS03865	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GUY19_RS03905	ENOG4105D5P	Methylmalonyl-coA mutase
GUY19_RS03935	ENOG4107S5I	aldo keto reductase
GUY19_RS03950	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GUY19_RS03960	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GUY19_RS04000	ENOG4105CCU	oxidase (Subunit III)
GUY19_RS04025	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GUY19_RS04030	ENOG4105C72	UPF0176 protein
GUY19_RS04040	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GUY19_RS04045	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GUY19_RS04085	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GUY19_RS04115	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GUY19_RS04155	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GUY19_RS04160	ENOG4108KMV	Glycosyl transferase (Group 1
GUY19_RS04170	ENOG4107SVH	Potassium channel protein
GUY19_RS04180	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GUY19_RS04190	ENOG41083MR	nifu domain-containing protein
GUY19_RS04210	ENOG4105E2A	Dehydrogenase
GUY19_RS04220	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GUY19_RS04230	ENOG4107VAM	peptidase, m28
GUY19_RS04240	ENOG4107XWI	flavin reductase domain protein, FMN-binding
GUY19_RS04255	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GUY19_RS04260	ENOG4105DCF	alanine dehydrogenase
GUY19_RS04265	ENOG4105K8N	protein family UPF0079, ATPase
GUY19_RS04270	ENOG4105CHM	Aminotransferase
GUY19_RS04275	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GUY19_RS04295	ENOG4105CN1	protease
GUY19_RS04310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GUY19_RS04315	ENOG4105DCI	Phosphohydrolase
GUY19_RS04320	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GUY19_RS04325	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GUY19_RS04330	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GUY19_RS04335	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GUY19_RS04355	ENOG4105CEV	competence damage-inducible protein
GUY19_RS04370	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GUY19_RS04385	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GUY19_RS04405	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GUY19_RS04410	ENOG4105C72	UPF0176 protein
GUY19_RS04435	ENOG4105CNU	cell division protein FtsK
GUY19_RS04455	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GUY19_RS04465	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GUY19_RS04470	ENOG4105C5R	Aminotransferase
GUY19_RS04475	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GUY19_RS04485	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GUY19_RS04490	ENOG4105CJ1	ABC, transporter
GUY19_RS04515	ENOG4105EMU	Dehydrogenase
GUY19_RS04525	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GUY19_RS04530	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GUY19_RS04535	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GUY19_RS04540	ENOG41067XB	TonB family
GUY19_RS04550	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GUY19_RS04555	ENOG4105CFH	Aspartokinase
GUY19_RS04570	ENOG4105D3R	alkyl hydroperoxide reductase
GUY19_RS04575	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GUY19_RS04580	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GUY19_RS04585	ENOG4106KE4	Dehydrogenase
GUY19_RS04600	ENOG4108ZCU	PPIases accelerate the folding of proteins
GUY19_RS04660	ENOG4105K64	Glycosyl transferase, family 2
GUY19_RS04675	ENOG4105D7N	magnesium and cobalt transport protein CorA
GUY19_RS04700	ENOG4105D5Q	Arginine ornithine antiporter
GUY19_RS04745	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GUY19_RS04805	ENOG41080C8	DUF218 domain
GUY19_RS04830	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GUY19_RS04840	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GUY19_RS04845	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GUY19_RS04850	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GUY19_RS04855	ENOG4108Z3N	Transcriptional regulator
GUY19_RS04865	ENOG4105WXV	50S ribosomal protein L32
GUY19_RS04870	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GUY19_RS04875	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GUY19_RS04880	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GUY19_RS04885	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GUY19_RS04890	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GUY19_RS04925	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GUY19_RS04935	ENOG41086DT	Membrane protein of unknown function
GUY19_RS04945	ENOG4107PHP	CheC --inhibitor of MCP methylation
GUY19_RS04950	ENOG4105CBS	Chea signal transduction histidine kinase
GUY19_RS04955	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GUY19_RS04960	ENOG4107YTP	response regulator receiver protein
GUY19_RS04965	ENOG4108V3W	Chemotaxis protein, CheW
GUY19_RS04975	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GUY19_RS04990	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GUY19_RS05005	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GUY19_RS05015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GUY19_RS05055	ENOG4105CHU	acetyl-coa acetyltransferase
GUY19_RS05095	ENOG4105CUT	histidyl-tRNA synthetase
GUY19_RS05100	ENOG4105C84	Histidine ammonia-lyase
GUY19_RS05110	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GUY19_RS05140	ENOG4105CPP	Dehydrogenase, E1 component
GUY19_RS05190	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS05200	ENOG4105CPQ	Dehydrogenase
GUY19_RS05215	ENOG4105CNT	hydrolase family 2
GUY19_RS05255	ENOG4105EDR	glucose galactose transporter
GUY19_RS05285	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
GUY19_RS05295	ENOG4108IG5	Transcriptional regulator
GUY19_RS05300	ENOG4105CK7	Sodium proline symporter
GUY19_RS05335	ENOG4105F5H	Glycosyl Hydrolase Family 88
GUY19_RS05350	ENOG4105CNT	hydrolase family 2
GUY19_RS05390	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS05400	ENOG4105FTV	AraC Family Transcriptional Regulator
GUY19_RS05405	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GUY19_RS05410	ENOG4107RJ1	sodium solute
GUY19_RS05415	ENOG4105CNT	hydrolase family 2
GUY19_RS05460	ENOG4107Y2X	deaminase
GUY19_RS05475	ENOG4105C5E	polysaccharide biosynthesis protein
GUY19_RS05480	ENOG4105EXC	Acyl-transferase
GUY19_RS05485	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GUY19_RS05495	ENOG4105CHR	reductase
GUY19_RS05500	ENOG4107TY6	Acylneuraminate cytidylyltransferase
GUY19_RS05515	ENOG4105D2T	synthase
GUY19_RS05540	ENOG4105CUB	amino acid
GUY19_RS05575	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GUY19_RS05590	ENOG4105CAK	Cell division ATP-binding protein ftsE
GUY19_RS05600	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GUY19_RS05615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GUY19_RS05655	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GUY19_RS05680	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GUY19_RS05695	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GUY19_RS05725	ENOG4108IUW	ABC transporter
GUY19_RS05735	ENOG4105EMU	Dehydrogenase
GUY19_RS05765	ENOG4108YYS	metal-dependent hydrolase (By similarity)
GUY19_RS05775	ENOG4105C10	Electron transfer flavoprotein
GUY19_RS05780	ENOG4105BZJ	Electron transfer flavoprotein
GUY19_RS05810	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
GUY19_RS05820	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GUY19_RS05825	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GUY19_RS05830	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GUY19_RS05870	ENOG4105MIR	Phenylalanine 4-monooxygenase
GUY19_RS05880	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GUY19_RS05885	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GUY19_RS05890	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GUY19_RS05895	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GUY19_RS05900	ENOG4107RI6	Anthranilate phosphoribosyltransferase
GUY19_RS05905	ENOG4105DDQ	anthranilate synthase
GUY19_RS05915	ENOG4108SA1	esterase
GUY19_RS05920	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS05925	ENOG4105TT1	Ragb susd domain-containing protein
GUY19_RS05975	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GUY19_RS05995	ENOG4105CPP	Dehydrogenase, E1 component
GUY19_RS06030	ENOG4105BZU	Histidine kinase
GUY19_RS06040	ENOG4105FYV	Amp nucleosidase
GUY19_RS06050	ENOG4105EFZ	amidohydrolase
GUY19_RS06070	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GUY19_RS06075	ENOG4107R4J	Chloride channel
GUY19_RS06095	ENOG4105HDK	L-asparaginase
GUY19_RS06100	ENOG4105F8V	Hydrolase, tatD family
GUY19_RS06105	ENOG4107R8N	Glycosyl transferase, family 2
GUY19_RS06145	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GUY19_RS06165	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GUY19_RS06175	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GUY19_RS06190	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GUY19_RS06205	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GUY19_RS06210	ENOG4105CI2	imidazolone-5-propionate hydrolase
GUY19_RS06230	ENOG4108RWI	nicotinamidase
GUY19_RS06240	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
GUY19_RS06255	ENOG4105DWT	malate dehydrogenase (quinone)
GUY19_RS06300	ENOG4105VEQ	Cold shock protein
GUY19_RS06360	ENOG4105CGP	Urocanate hydratase
GUY19_RS06365	ENOG4107VMB	Beta-lactamase domain protein
GUY19_RS06375	ENOG41088SP	formiminoglutamate hydrolase
GUY19_RS06390	ENOG4105CDY	transcriptional regulatory protein
GUY19_RS06395	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
GUY19_RS06410	ENOG4105FE9	pseudouridine synthase
GUY19_RS06420	ENOG4108Z12	YiaAB two helix domain-containing protein
GUY19_RS06425	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GUY19_RS06430	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GUY19_RS06435	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GUY19_RS06450	ENOG4105IIU	Aminopeptidase
GUY19_RS06460	ENOG4107QX8	SPFH domain, Band 7 family protein
GUY19_RS06490	ENOG4105IQ5	FAD linked oxidase domain protein
GUY19_RS06500	ENOG4105CFH	Aspartokinase
GUY19_RS06505	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GUY19_RS06515	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GUY19_RS06520	ENOG4105CGD	Nad-dependent epimerase dehydratase
GUY19_RS06555	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
GUY19_RS06570	ENOG41077A9	carbonic anhydrase
GUY19_RS06580	ENOG41062D9	Histidine kinase
GUY19_RS06590	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GUY19_RS06600	ENOG4107YJ4	chain length determinant protein
GUY19_RS06605	ENOG4105PSV	Polysaccharide Biosynthesis Protein
GUY19_RS06630	ENOG4105CKK	Glycosyl transferase, family 2
GUY19_RS06670	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GUY19_RS06675	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GUY19_RS06690	ENOG4105EQQ	protein containing aminopeptidase domain
GUY19_RS06710	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GUY19_RS06720	ENOG4105D3Q	Sugar transferase
GUY19_RS06725	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GUY19_RS06730	ENOG4105BZ8	glutamate synthase
GUY19_RS06740	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
GUY19_RS06750	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GUY19_RS06755	ENOG4105C26	Dehydrogenase
GUY19_RS06770	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GUY19_RS06775	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GUY19_RS06780	ENOG4105ETE	Transcriptional regulator (LacI family
GUY19_RS06785	ENOG4105D2N	Aldolase
GUY19_RS06790	ENOG4105CTQ	phosphohexokinase
GUY19_RS06795	ENOG410630P	Transcriptional regulator
GUY19_RS06805	ENOG4107QYV	phosphohexose isomerase
GUY19_RS06845	ENOG4105BZU	Histidine kinase
GUY19_RS06850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GUY19_RS06860	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GUY19_RS06865	ENOG4107RBB	ABC transporter, permease
GUY19_RS06870	ENOG4105C6K	Malic enzyme
GUY19_RS06875	ENOG4105CXT	aspartate transcarbamylase
GUY19_RS06880	ENOG4105CD3	dihydroorotase
GUY19_RS06885	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GUY19_RS06890	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GUY19_RS06930	ENOG4105BZA	Phosphoglycerate kinase
GUY19_RS06935	ENOG4105CPF	Cell wall formation (By similarity)
GUY19_RS06950	ENOG4105C72	UPF0176 protein
GUY19_RS06955	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GUY19_RS06965	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GUY19_RS06975	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GUY19_RS06985	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GUY19_RS07005	ENOG4105DDC	Oxidoreductase domain protein
GUY19_RS07010	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GUY19_RS07020	ENOG4105DPW	Major facilitator superfamily MFS_1
GUY19_RS07025	ENOG4108UHU	Aldolase
GUY19_RS07035	ENOG4105D2H	Uronic isomerase
GUY19_RS07040	ENOG4105CTX	dehydratase
GUY19_RS07045	ENOG4107QZW	Altronate oxidoreductase
GUY19_RS07060	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GUY19_RS07070	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS07075	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
GUY19_RS07080	ENOG4105CHR	reductase
GUY19_RS07085	ENOG4105ETE	Transcriptional regulator (LacI family
GUY19_RS07095	ENOG4108J20	pectate lyase
GUY19_RS07100	ENOG4105E4I	Glycoside hydrolase family 28
GUY19_RS07105	ENOG4107XII	Glycosyl Hydrolase Family 88
GUY19_RS07125	ENOG4105RWS	endonuclease I
GUY19_RS07140	ENOG410830R	acetyltransferase
GUY19_RS07170	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GUY19_RS07175	ENOG4108UXE	Protein tyrosine phosphatase
GUY19_RS07180	ENOG4106CKV	Pap2 superfamily protein
GUY19_RS07195	ENOG4107QJT	sodium dicarboxylate symporter
GUY19_RS07220	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GUY19_RS07225	ENOG4108HRK	Histidine kinase
GUY19_RS07230	ENOG4108NEV	two component transcriptional regulator, LytTR family
GUY19_RS07250	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GUY19_RS07265	ENOG4105S2T	inner membrane protein YbcI
GUY19_RS07280	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GUY19_RS07290	ENOG4108I0Z	Aconitate hydratase
GUY19_RS07310	ENOG4105BZU	Histidine kinase
GUY19_RS07345	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GUY19_RS07360	ENOG4108HMN	Caspase domain
GUY19_RS07370	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GUY19_RS07390	ENOG4105E33	succinate dehydrogenase
GUY19_RS07410	ENOG4105CA0	peroxidase
GUY19_RS07420	ENOG4105CA0	peroxidase
GUY19_RS07430	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GUY19_RS07435	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GUY19_RS07445	ENOG4105DFU	Cell wall formation (By similarity)
GUY19_RS07450	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GUY19_RS07455	ENOG4105CNI	cell division protein FtsW
GUY19_RS07460	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GUY19_RS07465	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GUY19_RS07470	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GUY19_RS07475	ENOG4105CJN	penicillin-binding protein
GUY19_RS07485	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GUY19_RS07490	ENOG4107YM1	mraZ protein
GUY19_RS07515	ENOG4105DY9	regulatoR
GUY19_RS07520	ENOG4105BZU	Histidine kinase
GUY19_RS07530	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GUY19_RS07560	ENOG4105EMN	RNA polymerase sigma factor
GUY19_RS07580	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GUY19_RS07590	ENOG4105C9A	Phoh family
GUY19_RS07620	ENOG4105E1F	short-chain dehydrogenase reductase
GUY19_RS07635	ENOG4105WH1	Two component transcriptional regulator luxr family
GUY19_RS07640	ENOG4105CUB	amino acid
GUY19_RS07655	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GUY19_RS07665	ENOG4107RH8	nuclease SbcCD subunit D
GUY19_RS07670	ENOG4105EYH	Exonuclease
GUY19_RS07700	ENOG4107QN2	dihydrolipoyl dehydrogenase
GUY19_RS07710	ENOG4105C0D	helicase
GUY19_RS07715	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
GUY19_RS07735	ENOG4105CWX	Alpha-1,2-mannosidase
GUY19_RS07765	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GUY19_RS07780	ENOG4105D1H	recombination factor protein RarA
GUY19_RS07785	ENOG4105D07	Signal peptide peptidase, SppA
GUY19_RS07790	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GUY19_RS07805	ENOG4105CHR	reductase
GUY19_RS07810	ENOG4107S01	Repressor protein MetJ
GUY19_RS07830	ENOG4108R99	pseudouridine synthase
GUY19_RS07845	ENOG4105CFG	Acts as a chaperone (By similarity)
GUY19_RS07875	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GUY19_RS07880	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GUY19_RS07885	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GUY19_RS07895	ENOG4105CHM	Aminotransferase
GUY19_RS07910	ENOG4108IJ0	Aspartate ammonia-lyase
GUY19_RS07915	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GUY19_RS07925	ENOG4105C5Z	peptidase
GUY19_RS07950	ENOG4107STG	mandelate racemase muconate lactonizing
GUY19_RS07955	ENOG4105CK2	sodium dicarboxylate symporter
GUY19_RS07980	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GUY19_RS07990	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GUY19_RS08010	ENOG4108HRK	Histidine kinase
GUY19_RS08025	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
GUY19_RS08035	ENOG4105EUB	pirin domain protein
GUY19_RS08040	ENOG4107RJ1	sodium solute
GUY19_RS08050	ENOG4105BZ1	(ABC) transporter
GUY19_RS08080	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
GUY19_RS08090	ENOG4108JYZ	YitT family
GUY19_RS08125	ENOG4105ZMH	deoxynucleoside kinase
GUY19_RS08160	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GUY19_RS08165	ENOG4105CEV	competence damage-inducible protein
GUY19_RS08190	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GUY19_RS08200	ENOG4105C9K	Endothelin-converting enzyme 1
GUY19_RS08205	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GUY19_RS08245	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GUY19_RS08255	ENOG4108Z9Z	response to DNA damage stimulus
GUY19_RS08265	ENOG410849A	acetyltransferase, (GNAT) family
GUY19_RS08270	ENOG4105BZS	acriflavin resistance protein
GUY19_RS08345	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GUY19_RS08375	ENOG4105HHA	aminodeoxychorismate lyase
GUY19_RS08390	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GUY19_RS08435	ENOG4107QX3	carboxylase
GUY19_RS08440	ENOG4105CN9	Peptidase m42 family protein
GUY19_RS08445	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GUY19_RS08455	ENOG4105D49	3-dehydroquinate synthase
GUY19_RS08470	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GUY19_RS08490	ENOG4105CN1	protease
GUY19_RS08500	ENOG4105CRK	lysyL-tRNA synthetase
GUY19_RS08510	ENOG4105VDW	Csbd family
GUY19_RS08525	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
GUY19_RS08540	ENOG4105BZ1	(ABC) transporter
GUY19_RS08575	ENOG41076HS	cation diffusion facilitator family transporter
GUY19_RS08595	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GUY19_RS08625	ENOG4105BZ1	(ABC) transporter
GUY19_RS08630	ENOG4107QJZ	Glycosyl transferase, family 2
GUY19_RS08650	ENOG4107TDE	lipolytic protein G-D-S-L family
GUY19_RS08655	ENOG4107TDE	lipolytic protein G-D-S-L family
GUY19_RS08665	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GUY19_RS08670	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GUY19_RS08690	ENOG410901F	(LipO)protein
GUY19_RS08705	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GUY19_RS08710	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GUY19_RS08740	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GUY19_RS08745	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GUY19_RS08750	ENOG4105CPK	Glycosyl transferase (Group 1
GUY19_RS08760	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GUY19_RS08780	ENOG4108IUX	(ABC) transporter
GUY19_RS08785	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GUY19_RS08790	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GUY19_RS08795	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GUY19_RS08800	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GUY19_RS08805	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GUY19_RS08810	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GUY19_RS08845	ENOG4108Z7G	MaoC domain protein dehydratase
GUY19_RS08855	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GUY19_RS08865	ENOG4107XU6	Glycosyl transferase (Group 1
GUY19_RS08870	ENOG4108W0I	acetyltransferase
GUY19_RS08875	ENOG4105CKK	Glycosyl transferase, family 2
GUY19_RS08885	ENOG4107S6X	Glycosyl transferase, family 2
GUY19_RS08895	ENOG4107R51	Glycosyl transferase, family 2
GUY19_RS08900	ENOG4105ECJ	Glycosyl Transferase
GUY19_RS08920	ENOG4108UW5	maltose o-acetyltransferase
GUY19_RS08925	ENOG4105EY8	ABC transporter
GUY19_RS08935	ENOG4105C30	Nad-dependent epimerase dehydratase
GUY19_RS08940	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
GUY19_RS08960	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GUY19_RS08965	ENOG4105CKK	Glycosyl transferase, family 2
GUY19_RS08975	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GUY19_RS08980	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GUY19_RS08990	ENOG4105CAQ	asparagine synthetase
GUY19_RS09000	ENOG4105CQB	FAD linked oxidase domain protein
GUY19_RS09005	ENOG4108QBX	(LipO)protein
GUY19_RS09010	ENOG4108KPZ	tonB-dependent Receptor
GUY19_RS09035	ENOG4108ZCU	PPIases accelerate the folding of proteins
GUY19_RS09085	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
GUY19_RS09115	ENOG4105C2C	drug resistance transporter, Bcr CflA
GUY19_RS09125	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GUY19_RS09130	ENOG4105EHG	Permease protein
GUY19_RS09135	ENOG4107R4I	Periplasmic binding protein
GUY19_RS09150	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
GUY19_RS09160	ENOG4105CZH	peptidase
GUY19_RS09165	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GUY19_RS09180	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GUY19_RS09190	ENOG4105C4K	Nad synthetase
GUY19_RS09195	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GUY19_RS09200	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GUY19_RS09205	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GUY19_RS09215	ENOG4105CA9	Pyruvate kinase
GUY19_RS09220	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
GUY19_RS09230	ENOG4105DNZ	Alpha Beta Hydrolase
GUY19_RS09235	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GUY19_RS09240	ENOG4105EMN	RNA polymerase sigma factor
GUY19_RS09250	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GUY19_RS09270	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GUY19_RS09275	ENOG4105D3Q	Sugar transferase
GUY19_RS09290	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GUY19_RS09300	ENOG4105C28	cystathionine
GUY19_RS09305	ENOG4108REF	Sporulation integral membrane protein ytvi
GUY19_RS09315	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GUY19_RS09325	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GUY19_RS09330	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GUY19_RS09335	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GUY19_RS09340	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GUY19_RS09355	ENOG4105E0X	reductase
GUY19_RS09360	ENOG4105CI3	gtp-binding protein typa
GUY19_RS09365	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GUY19_RS09370	ENOG4105CE4	GlcNAc 6-P deacetylase
GUY19_RS09375	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GUY19_RS09380	ENOG4108RWN	rrna methyltransferase
GUY19_RS09385	ENOG4105BZU	Histidine kinase
GUY19_RS09400	ENOG4105CSM	endonuclease III
GUY19_RS09410	ENOG4105VZ9	UPF0235 protein
GUY19_RS09430	ENOG4105BZU	Histidine kinase
GUY19_RS09435	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GUY19_RS09450	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GUY19_RS09460	ENOG4108HRK	Histidine kinase
GUY19_RS09470	ENOG4105DN3	alpha-2-macroglobulin domain protein
GUY19_RS09480	ENOG4108JQB	penicillin-binding protein 1C
GUY19_RS09505	ENOG4105C26	Dehydrogenase
GUY19_RS09510	ENOG4105W4W	Transcriptional regulator
GUY19_RS09520	ENOG4105FFC	UPF0187 protein
GUY19_RS09525	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GUY19_RS09540	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GUY19_RS09565	ENOG4105QNR	S1 RNA binding domain protein
GUY19_RS09570	ENOG4105K4T	epimerase
GUY19_RS09635	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GUY19_RS09640	ENOG4105DKB	L-sorbosone dehydrogenase
GUY19_RS09655	ENOG4108UVJ	appr-1-p processing domain protein
GUY19_RS09670	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GUY19_RS09675	ENOG4105CAT	Cytidine monophosphate kinase
GUY19_RS09700	ENOG4105CPN	adenine deaminase
GUY19_RS09715	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GUY19_RS09740	ENOG4107QN2	dihydrolipoyl dehydrogenase
GUY19_RS09750	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GUY19_RS09780	ENOG4105W5Q	DNA repair protein (RadC
GUY19_RS09830	ENOG4105BZU	Histidine kinase
GUY19_RS09835	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
GUY19_RS09865	ENOG4105BZU	Histidine kinase
GUY19_RS09870	ENOG4105BZU	Histidine kinase
GUY19_RS09875	ENOG4105WH1	Two component transcriptional regulator luxr family
GUY19_RS09910	ENOG4105CFF	transcriptional regulator
GUY19_RS09960	ENOG4105C6E	dna polymerase iii
GUY19_RS09970	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GUY19_RS10005	ENOG4105CHM	Aminotransferase
GUY19_RS10020	ENOG4105DQ4	alcohol dehydrogenase
GUY19_RS10025	ENOG4105VCH	membrane
GUY19_RS10050	ENOG4105ED2	Beta-lactamase
GUY19_RS10055	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GUY19_RS10060	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GUY19_RS10085	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GUY19_RS10090	ENOG4105K56	Transcriptional regulator
GUY19_RS10095	ENOG4105C2I	pirin domain protein
GUY19_RS10105	ENOG4105C2I	pirin domain protein
GUY19_RS10115	ENOG4105CDV	Ompa motb domain protein
GUY19_RS10145	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GUY19_RS10160	ENOG41077A9	carbonic anhydrase
GUY19_RS10180	ENOG4105CKW	Inner membrane protein yedI
GUY19_RS10200	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GUY19_RS10265	ENOG4105KWG	Pfam:DUF1696
GUY19_RS10270	ENOG4108RTU	Aldolase
GUY19_RS10295	ENOG41082YX	Transcriptional regulator, arsr family
GUY19_RS10300	ENOG4105NZG	Ferredoxin
GUY19_RS10305	ENOG4105PAD	Hydrolase
GUY19_RS10315	ENOG4105C26	Dehydrogenase
GUY19_RS10320	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GUY19_RS10325	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUY19_RS10330	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GUY19_RS10335	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUY19_RS10355	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GUY19_RS10360	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUY19_RS10365	ENOG4105DF2	NADH dehydrogenase subunit j
GUY19_RS10390	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUY19_RS10395	ENOG4105D65	subunit l
GUY19_RS10410	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUY19_RS10430	ENOG4105WH1	Two component transcriptional regulator luxr family
GUY19_RS10435	ENOG4105BZU	Histidine kinase
GUY19_RS10450	ENOG4105C9M	aspartyl-trna synthetase
GUY19_RS10465	ENOG4105DY9	regulatoR
GUY19_RS10470	ENOG4105C2F	Histidine kinase
GUY19_RS10480	ENOG4105CJ1	ABC, transporter
GUY19_RS10505	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GUY19_RS10520	ENOG4105EAA	nucleoside
GUY19_RS10525	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GUY19_RS10530	ENOG4105SFS	phosphoesterase RecJ domain protein
GUY19_RS10535	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GUY19_RS10540	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GUY19_RS10560	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
GUY19_RS10585	ENOG4105CNI	cell division protein FtsW
GUY19_RS10590	ENOG4105CJN	penicillin-binding protein
GUY19_RS10610	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GUY19_RS10655	ENOG4105VEQ	Cold shock protein
GUY19_RS10660	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GUY19_RS10670	ENOG4108ZIT	Ferredoxin, 2FE-2S
GUY19_RS10690	ENOG4105DA4	cytochrome c-type biogenesis protein
GUY19_RS10725	ENOG41080HI	glycine oxidase
GUY19_RS10730	ENOG4105C5X	domain protein
GUY19_RS10735	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GUY19_RS10790	ENOG4107QHQ	amino acid
GUY19_RS10800	ENOG41072GX	Peptidase M22 Glycoprotease
GUY19_RS10825	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GUY19_RS10830	ENOG4105VG0	50S ribosomal protein l34
GUY19_RS10865	ENOG4105C1J	atp-dependent rna helicase
GUY19_RS10875	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GUY19_RS10885	ENOG4108YYC	ycei family
GUY19_RS10895	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GUY19_RS10900	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GUY19_RS10925	ENOG4108IQK	o-acetylhomoserine
GUY19_RS10930	ENOG4105DWV	Homoserine O-trans-acetylase
GUY19_RS10935	ENOG4105D6E	homoserine dehydrogenase
GUY19_RS10945	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GUY19_RS10990	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
GUY19_RS10995	ENOG4105CHV	Transcription elongation factor NusA
GUY19_RS11000	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GUY19_RS11025	ENOG4108ZG0	Ompa motb domain protein
GUY19_RS11045	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GUY19_RS11050	ENOG4105E39	Enoyl-CoA hydratase
GUY19_RS11060	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GUY19_RS11090	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GUY19_RS11095	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GUY19_RS11100	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GUY19_RS11115	ENOG4105D7W	serine acetyltransferase
GUY19_RS11145	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GUY19_RS11155	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GUY19_RS11165	ENOG4105IIU	Aminopeptidase
GUY19_RS11175	ENOG4105DSJ	YicC domain protein
GUY19_RS11190	ENOG4107TAE	Glycosyl transferase (Group 1
GUY19_RS11205	ENOG4105EMN	RNA polymerase sigma factor
GUY19_RS11225	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GUY19_RS11270	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GUY19_RS11290	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GUY19_RS11295	ENOG4105EE5	Membrane protein terC
GUY19_RS11300	ENOG4108VPT	UPF0234 protein
GUY19_RS11330	ENOG4108JA2	transcriptioN-repair coupling factor
GUY19_RS11435	ENOG4107ZXU	DSBA oxidoreductase
GUY19_RS11450	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GUY19_RS11470	ENOG4105CSH	Transporter
GUY19_RS11490	ENOG4105BZU	Histidine kinase
GUY19_RS11495	ENOG4105CHM	Aminotransferase
GUY19_RS11510	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GUY19_RS11515	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GUY19_RS11520	ENOG4107T8Q	Glycosyl transferase (Group 1
GUY19_RS11525	ENOG4108YYQ	gCN5-related N-acetyltransferase
GUY19_RS11530	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GUY19_RS11550	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GUY19_RS11965	ENOG4105EY8	ABC transporter
GUY19_RS11980	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GUY19_RS12025	ENOG4105WH1	Two component transcriptional regulator luxr family
GUY19_RS12050	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GUY19_RS12060	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GUY19_RS12095	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GUY19_RS12110	ENOG4105CUX	Signal transduction histidine kinase
GUY19_RS12115	ENOG4105C3M	thioredoxin reductase
GUY19_RS12120	ENOG4108X4D	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GUY19_RS12145	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GUY19_RS12175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GUY19_RS12185	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GUY19_RS12190	ENOG4105FQP	Beta-lactamase
GUY19_RS12195	ENOG4105C19	ABC transporter
GUY19_RS12225	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GUY19_RS12240	ENOG4105DAP	Nicotinate phosphoribosyltransferase
GUY19_RS12250	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GUY19_RS12255	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GUY19_RS12260	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GUY19_RS12265	ENOG4107QNG	Phosphoribosylglycinamide synthetase
GUY19_RS12270	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
GUY19_RS12275	ENOG4107QWK	SAICAR synthetase
GUY19_RS12280	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GUY19_RS12285	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GUY19_RS12290	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GUY19_RS12295	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GUY19_RS12300	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GUY19_RS12345	ENOG4105BZU	Histidine kinase
GUY19_RS12355	ENOG4107R39	(ABC) transporter
GUY19_RS12365	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GUY19_RS12370	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GUY19_RS12375	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GUY19_RS12390	ENOG4107R7Y	intracellular protease Pfpi family
GUY19_RS12415	ENOG4105BZU	Histidine kinase
GUY19_RS12420	ENOG4105DGU	Histone deacetylase
GUY19_RS12430	ENOG41065KQ	synthase
GUY19_RS12445	ENOG4105H3G	oxidoreductase
GUY19_RS12485	ENOG4106UW1	Major Facilitator superfamily
GUY19_RS12515	ENOG4105VEQ	Cold shock protein
GUY19_RS12520	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GUY19_RS12525	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
GUY19_RS12535	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GUY19_RS12590	ENOG4107QN2	dihydrolipoyl dehydrogenase
GUY19_RS12600	ENOG4105FDR	Membrane
GUY19_RS12615	ENOG4105C7S	Dehydrogenase
GUY19_RS12620	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GUY19_RS12675	ENOG4105VDW	Csbd family
GUY19_RS12700	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GUY19_RS12715	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GUY19_RS12745	ENOG4105CPP	Dehydrogenase, E1 component
GUY19_RS12775	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GUY19_RS12780	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GUY19_RS12800	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GUY19_RS12805	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GUY19_RS12835	ENOG4105DT9	hydrolase family 43
GUY19_RS12840	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GUY19_RS12860	ENOG4105EXW	epimerase dehydratase
GUY19_RS12870	ENOG4107S2Z	UPF0761 membrane protein
GUY19_RS12885	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GUY19_RS12900	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GUY19_RS12915	ENOG4109015	Biopolymer transport protein exbD tolR
GUY19_RS12920	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GUY19_RS12925	ENOG41074B2	UPF0747 protein
GUY19_RS12930	ENOG4105EXC	Acyl-transferase
GUY19_RS12935	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GUY19_RS12940	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GUY19_RS12950	ENOG41083ND	50S ribosomal protein L33
GUY19_RS12955	ENOG4107RAQ	aminopeptidase
GUY19_RS12960	ENOG4105KDC	50s ribosomal protein l28
GUY19_RS12970	ENOG4105KME	endoribonuclease L-psp
GUY19_RS12980	ENOG4105C8Y	Acetylornithine aminotransferase
GUY19_RS13000	ENOG4105D52	delta-aminolevulinic acid dehydratase
GUY19_RS13010	ENOG4107R7I	amino acid
GUY19_RS13025	ENOG4107RZC	phospholipase d
GUY19_RS13045	ENOG4105CHR	reductase
GUY19_RS13060	ENOG4105CH2	amidohydrolase
GUY19_RS13070	ENOG4107FW0	short-chain dehydrogenase reductase
GUY19_RS13120	ENOG4105CN1	protease
GUY19_RS13125	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GUY19_RS13130	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GUY19_RS13170	ENOG4105D78	K07001 NTE family protein
GUY19_RS13220	ENOG4105BZU	Histidine kinase
GUY19_RS13230	ENOG4107SUZ	Sodium/hydrogen exchanger family
GUY19_RS13235	ENOG4105C5H	ABC transporter
GUY19_RS13250	ENOG4105E0A	ABC, transporter
GUY19_RS13255	ENOG4107RMN	lycopene cyclase
GUY19_RS13265	ENOG4108URH	decarboxylase
GUY19_RS13270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GUY19_RS13275	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GUY19_RS13280	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GUY19_RS13285	ENOG4108UKI	Enoyl-CoA hydratase
GUY19_RS13310	ENOG4108RAV	Conserved protein
GUY19_RS13315	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GUY19_RS13330	ENOG4105CS2	ec 3.2.1.21
GUY19_RS13345	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GUY19_RS13350	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GUY19_RS13385	ENOG4108UJV	acyl-CoA thioesterase i
GUY19_RS13400	ENOG4108IUK	alpha amylase, catalytic
GUY19_RS13405	ENOG4105EMU	Dehydrogenase
GUY19_RS13415	ENOG4105CT4	transporter
GUY19_RS13430	ENOG4105F32	YngK protein
GUY19_RS13440	ENOG4105CP2	von willebrand factor, type a
GUY19_RS13460	ENOG4105C9Q	fumarate hydratase class II
GUY19_RS13475	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GUY19_RS13485	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GUY19_RS13495	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GUY19_RS13540	ENOG4105ECY	inositol monophosphatase
GUY19_RS13545	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GUY19_RS13550	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GUY19_RS13555	ENOG4105KZX	Pterin carbinolamine dehydratase
GUY19_RS13580	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GUY19_RS13595	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GUY19_RS13600	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GUY19_RS13605	ENOG4108YZG	isomerase
GUY19_RS13615	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GUY19_RS13620	ENOG4108KQJ	Type 11 methyltransferase
GUY19_RS13625	ENOG4105D60	lipoprotein releasing system transmembrane protein
GUY19_RS13630	ENOG4105C0D	helicase
GUY19_RS13640	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GUY19_RS13655	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GUY19_RS13660	ENOG4105KVH	Transcriptional regulator
GUY19_RS13665	ENOG4105DR4	Methyltransferase
GUY19_RS13680	ENOG4105C3R	Methionine synthase
GUY19_RS13685	ENOG4105SYT	Methylenetetrahydrofolate reductase
GUY19_RS13705	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GUY19_RS13725	ENOG4107S1W	4-alpha-glucanotransferase
GUY19_RS13740	ENOG4105C3M	thioredoxin reductase
GUY19_RS13760	ENOG4105BZP	glycoside hydrolase 15-related
GUY19_RS13770	ENOG4105BZU	Histidine kinase
GUY19_RS13790	ENOG4105CSA	Coproporphyrinogen iii oxidase
GUY19_RS13810	ENOG4105K46	50S ribosomal protein l27
GUY19_RS13815	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GUY19_RS13825	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
GUY19_RS13830	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GUY19_RS13910	ENOG410832A	alpha/beta hydrolase fold
GUY19_RS13915	ENOG4107S1E	Beta-lactamase
GUY19_RS13920	ENOG4105C9K	Endothelin-converting enzyme 1
GUY19_RS13925	ENOG4105EUB	pirin domain protein
GUY19_RS13930	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GUY19_RS13945	ENOG4105CSR	polyphosphate kinase 2
GUY19_RS13975	ENOG4108UQ1	hydrolase, family 25
GUY19_RS13980	ENOG4105K6T	rare lipoprotein A
GUY19_RS14000	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GUY19_RS14025	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GUY19_RS14035	ENOG4107YR5	Diacylglycerol kinase
GUY19_RS14040	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
GUY19_RS14075	ENOG4105E6M	Sulphatase-modifying factor protein
GUY19_RS14080	ENOG4105MJ2	Competence protein
GUY19_RS14095	ENOG4105CGK	Exodeoxyribonuclease III
GUY19_RS14110	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GUY19_RS14120	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GUY19_RS14155	ENOG4105CJ3	phosphate transporter
GUY19_RS14160	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GUY19_RS14180	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GUY19_RS14185	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GUY19_RS14190	ENOG4108JQ6	ABC transporter
GUY19_RS14195	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GUY19_RS14235	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GUY19_RS14240	ENOG4107R0V	Pyruvate dehydrogenase
GUY19_RS14250	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GUY19_RS14255	ENOG4105SCY	DNAK suppressor
GUY19_RS14260	ENOG4105FE9	pseudouridine synthase
GUY19_RS14265	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GUY19_RS14285	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GUY19_RS14295	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GUY19_RS14305	ENOG4108IUZ	ABC transporter
GUY19_RS14335	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GUY19_RS14355	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GUY19_RS14360	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GUY19_RS14370	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GUY19_RS14375	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GUY19_RS14380	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GUY19_RS14390	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GUY19_RS14400	ENOG4105C1G	acyl-Coa dehydrogenase
GUY19_RS14410	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
GUY19_RS14425	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GUY19_RS14450	ENOG4105DF6	Fe-S oxidoreductase
GUY19_RS14455	ENOG4105DF6	Fe-S oxidoreductase
GUY19_RS14465	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GUY19_RS14480	ENOG4105CHU	acetyl-coa acetyltransferase
GUY19_RS14490	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GUY19_RS14500	ENOG4105BZ1	(ABC) transporter
GUY19_RS14540	ENOG4105BZ1	(ABC) transporter
GUY19_RS14550	ENOG4107R6T	Involved in the transcription termination process (By similarity)
GUY19_RS14560	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GUY19_RS14570	ENOG4105VIE	preprotein translocase, subunit YajC
GUY19_RS14580	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GUY19_RS14610	ENOG4105D64	Mechanosensitive ion channel
GUY19_RS14625	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GUY19_RS14630	ENOG4105BZU	Histidine kinase
GUY19_RS14650	ENOG4105CUB	amino acid
GUY19_RS14675	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GUY19_RS14685	ENOG4105KNE	Phosphatidate cytidylyltransferase
GUY19_RS14690	ENOG4105D82	Glutamate dehydrogenase
GUY19_RS14695	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
GUY19_RS14700	ENOG4106032	Glutathionylspermidine synthase
GUY19_RS14710	ENOG4108ZGC	gaf domain protein
GUY19_RS14715	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GUY19_RS14720	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GUY19_RS14725	ENOG4105J5G	Transferase hexapeptide repeat containing protein
GUY19_RS14730	ENOG4107QQG	Dehydrogenase
GUY19_RS14735	ENOG4105CMR	udp-glucose 4-epimerase
GUY19_RS14740	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GUY19_RS14750	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GUY19_RS14790	ENOG4107QKZ	Ompa motb domain protein
GUY19_RS14795	ENOG4105DI5	UPF0365 protein
GUY19_RS14820	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GUY19_RS14840	ENOG4105C5Z	peptidase
GUY19_RS14870	ENOG4105CKK	Glycosyl transferase, family 2
GUY19_RS14875	ENOG4108KQJ	Type 11 methyltransferase
GUY19_RS14905	ENOG4108KEZ	Dehydrogenase
GUY19_RS14910	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
GUY19_RS14930	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
GUY19_RS14950	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
GUY19_RS14965	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GUY19_RS14970	ENOG4105C5S	asparaginyl-tRNA synthetase
GUY19_RS15005	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GUY19_RS15015	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GUY19_RS15090	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GUY19_RS15140	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GUY19_RS15150	ENOG4108JUA	Transcriptional regulator
GUY19_RS15170	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GUY19_RS15195	ENOG4105CUJ	penicillin amidase
GUY19_RS15250	ENOG4105C9K	Endothelin-converting enzyme 1
GUY19_RS15255	ENOG4108YZN	class I peptide chain release factor
GUY19_RS15260	ENOG4105CJW	magnesium transporter
GUY19_RS15265	ENOG4105DDG	Cyanophycinase
GUY19_RS15285	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
GUY19_RS15295	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GUY19_RS15310	ENOG4105C2M	dna polymerase I
GUY19_RS15320	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GUY19_RS15340	ENOG4108V0P	LemA family
GUY19_RS15425	ENOG4107RGD	Major Facilitator superfamily
GUY19_RS15430	ENOG4105PGM	cation diffusion facilitator family transporter
GUY19_RS15435	ENOG4105E0K	tonB-dependent siderophore receptor
GUY19_RS15450	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GUY19_RS15460	ENOG41080R2	UPF0102 protein
GUY19_RS15465	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GUY19_RS15475	ENOG4105ESV	Glycosyl transferase, family 4
GUY19_RS15500	ENOG4105E6M	Sulphatase-modifying factor protein
GUY19_RS15520	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GUY19_RS15525	ENOG4108JQC	penicillin-binding protein 1A
GUY19_RS15545	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GUY19_RS15555	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GUY19_RS15560	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GUY19_RS15565	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GUY19_RS15570	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GUY19_RS15585	ENOG4105F0N	pyrophosphate phospho-hydrolase
GUY19_RS15600	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GUY19_RS15610	ENOG4105E0X	reductase
GUY19_RS15650	ENOG4107QR9	Iron-sulfur cluster binding protein
GUY19_RS15655	ENOG4105IIU	Aminopeptidase
GUY19_RS15660	ENOG4105IIU	Aminopeptidase
GUY19_RS15665	ENOG4105IIU	Aminopeptidase
GUY19_RS15670	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GUY19_RS15685	ENOG410624X	efflux transporter, rnd family, mfp subunit
GUY19_RS15695	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GUY19_RS15715	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GUY19_RS15735	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GUY19_RS15765	ENOG410902V	Modulates RecA activity (By similarity)
GUY19_RS15770	ENOG4105FR1	rard protein
GUY19_RS15775	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS15780	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GUY19_RS15785	ENOG4107RNH	Outer membrane receptor FepA
GUY19_RS15805	ENOG4105CE1	Ferrous iron transport protein b
GUY19_RS15810	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GUY19_RS15815	ENOG4105EV9	Alpha Beta Hydrolase
GUY19_RS15835	ENOG4105BZU	Histidine kinase
GUY19_RS15845	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GUY19_RS15860	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GUY19_RS15865	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GUY19_RS15880	ENOG4105DDQ	anthranilate synthase
GUY19_RS15900	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GUY19_RS15915	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GUY19_RS15920	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GUY19_RS15935	ENOG4105C34	Pseudouridine synthase
GUY19_RS15945	ENOG4107S17	Phosphate-binding protein
GUY19_RS15965	ENOG4109015	Biopolymer transport protein exbD tolR
GUY19_RS15980	ENOG4105DXN	mazG family
GUY19_RS15985	ENOG4107QKV	phosphomannomutase
GUY19_RS15990	ENOG4107QI6	Cysteine desulfurase
GUY19_RS16010	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GUY19_RS16015	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GUY19_RS16020	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GUY19_RS16035	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GUY19_RS16050	ENOG4108IQE	Amp-dependent synthetase and ligase
GUY19_RS16070	ENOG4105CHU	acetyl-coa acetyltransferase
GUY19_RS16075	ENOG4105C1G	acyl-Coa dehydrogenase
GUY19_RS16115	ENOG4105K70	DNA-binding protein
GUY19_RS16125	ENOG4105C03	ribonuclease
GUY19_RS16145	ENOG4105CSM	endonuclease III
GUY19_RS16155	ENOG4108AEY	RNA polymerase sigma factor
GUY19_RS16175	ENOG4105WH9	RNA polymerase
GUY19_RS16210	ENOG4105F6J	Alpha beta hydrolase fold
GUY19_RS16250	ENOG4105CP7	Triose-phosphate isomerase
GUY19_RS16260	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GUY19_RS16270	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GUY19_RS16320	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GUY19_RS16325	ENOG4105C0P	Mg chelatase subunit ChlI
GUY19_RS16335	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GUY19_RS16345	ENOG4105BZ1	(ABC) transporter
GUY19_RS16355	ENOG4106HB6	Alpha beta hydrolase
GUY19_RS16360	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GUY19_RS16370	ENOG4105CG3	alpha amylase, catalytic region
GUY19_RS16395	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GUY19_RS16410	ENOG4105D8V	Glucose sorbosone dehydrogenase
GUY19_RS16450	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GUY19_RS16460	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GUY19_RS16465	ENOG41083X6	30S ribosomal protein S21
GUY19_RS16470	ENOG4105C1G	acyl-Coa dehydrogenase
GUY19_RS16500	ENOG41061P3	phosphosulfolactate synthase
GUY19_RS16530	ENOG4105DQR	SNARE associated Golgi
GUY19_RS16535	ENOG4105E2X	shikimate dehydrogenase
GUY19_RS16560	ENOG4105C2F	Histidine kinase
GUY19_RS16565	ENOG4108NEV	two component transcriptional regulator, LytTR family
GUY19_RS16580	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GUY19_RS16595	ENOG4105F0N	pyrophosphate phospho-hydrolase
GUY19_RS16615	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
GUY19_RS16625	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GUY19_RS16630	ENOG4105C9F	isomerase
GUY19_RS16640	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GUY19_RS16645	ENOG4107QR9	Iron-sulfur cluster binding protein
GUY19_RS16665	ENOG4105ERH	Fumarylacetoacetate hydrolase
GUY19_RS16670	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GUY19_RS16680	ENOG4107SUZ	Sodium/hydrogen exchanger family
GUY19_RS16685	ENOG4105CPC	Aldo Keto reductase
GUY19_RS16740	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GUY19_RS16745	ENOG4105KT5	UmuD protein
GUY19_RS16865	ENOG4107ENK	receptor
GUY19_RS16870	ENOG4108VX5	3-methyladenine DNA glycosylase
GUY19_RS16890	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GUY19_RS16900	ENOG4106WTF	Glycosyl transferase, family 2
GUY19_RS16915	ENOG4105EMN	RNA polymerase sigma factor
GUY19_RS16925	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GUY19_RS16930	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GUY19_RS16935	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GUY19_RS16940	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GUY19_RS16945	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
GUY19_RS16985	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GUY19_RS16990	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GUY19_RS16995	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GUY19_RS17000	ENOG4107VNI	ribosomal protein l10
GUY19_RS17005	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GUY19_RS17010	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GUY19_RS17015	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GUY19_RS17035	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GUY19_RS17040	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GUY19_RS17045	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GUY19_RS17050	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GUY19_RS17060	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GUY19_RS17065	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GUY19_RS17070	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GUY19_RS17075	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GUY19_RS17080	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GUY19_RS17085	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GUY19_RS17090	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GUY19_RS17095	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GUY19_RS17100	ENOG4108628	50s ribosomal protein l29
GUY19_RS17105	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GUY19_RS17110	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GUY19_RS17115	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GUY19_RS17125	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GUY19_RS17130	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GUY19_RS17135	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GUY19_RS17140	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GUY19_RS17145	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GUY19_RS17150	ENOG4105VPB	50S ribosomal protein L30
GUY19_RS17155	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GUY19_RS17160	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GUY19_RS17165	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GUY19_RS17170	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GUY19_RS17175	ENOG410864M	50S ribosomal protein L36
GUY19_RS17180	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GUY19_RS17185	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GUY19_RS17190	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GUY19_RS17195	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GUY19_RS17200	ENOG4108ZT0	50S ribosomal protein l17
GUY19_RS17205	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GUY19_RS17225	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GUY19_RS17230	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GUY19_RS17270	ENOG4105DG4	malate L-lactate dehydrogenase
GUY19_RS17280	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GUY19_RS17290	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GUY19_RS17315	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GUY19_RS17330	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GUY19_RS17360	ENOG4105C0H	protease
GUY19_RS17370	ENOG4105C26	Dehydrogenase
GUY19_RS17395	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GUY19_RS17445	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GUY19_RS17450	ENOG4105BZU	Histidine kinase
GUY19_RS17460	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
GUY19_RS17465	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GUY19_RS17470	ENOG4105FFC	UPF0187 protein
GUY19_RS17480	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GUY19_RS17490	ENOG4105HMI	Membrane
GUY19_RS17495	ENOG4105EI2	Pseudouridine synthase
GUY19_RS17505	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GUY19_RS17510	ENOG4108UJD	30S ribosomal protein S9
GUY19_RS17515	ENOG4105CE9	30S ribosomal protein S2
GUY19_RS17520	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GUY19_RS17555	ENOG4105BZU	Histidine kinase
GUY19_RS17560	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GUY19_RS17570	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GUY19_RS17585	ENOG4105CHR	reductase
GUY19_RS17600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GUY19_RS17605	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GUY19_RS17610	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GUY19_RS17630	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GUY19_RS17650	ENOG4105MA6	gCN5-related N-acetyltransferase
GUY19_RS17670	ENOG4105VFE	sira family
GUY19_RS17685	ENOG4105CQ7	ATP-dependent helicase
GUY19_RS17690	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GUY19_RS17730	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GUY19_RS17740	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GUY19_RS17775	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GUY19_RS17815	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GUY19_RS17830	ENOG4105DBI	uridine monophosphokinase
GUY19_RS17835	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GUY19_RS17845	ENOG41081WG	50s ribosomal protein l31
GUY19_RS17860	ENOG4105FA2	dna polymerase iii
GUY19_RS17875	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
GUY19_RS17885	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GUY19_RS17895	ENOG4105KNA	-acetyltransferase
GUY19_RS17930	ENOG4105MA4	psp1 domain protein
GUY19_RS17965	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GUY19_RS17970	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GUY19_RS17980	ENOG4105RWF	major outer membrane protein OmpA
GUY19_RS17990	ENOG4108Y6J	UPF0403 protein
GUY19_RS18000	ENOG4105DGW	oligopeptidase A
GUY19_RS18005	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GUY19_RS18010	ENOG4105C2X	Arabinose 5-phosphate isomerase
GUY19_RS18015	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GUY19_RS18020	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GUY19_RS18050	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GUY19_RS18055	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GUY19_RS18065	ENOG4107QSI	ABC, transporter
GUY19_RS18090	ENOG4108NEV	two component transcriptional regulator, LytTR family
GUY19_RS18095	ENOG4105BZU	Histidine kinase
GUY19_RS18125	ENOG4107S85	alpha-2-macroglobulin domain protein
GUY19_RS18150	ENOG4105CAY	ferredoxin--nadp reductase
GUY19_RS18160	ENOG4105D3R	alkyl hydroperoxide reductase
GUY19_RS18165	ENOG4105CH7	arginosuccinase
GUY19_RS18180	ENOG4107T6X	nag kinase
GUY19_RS18190	ENOG4105CDH	Citrulline--aspartate ligase
GUY19_RS18195	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GUY19_RS18200	ENOG4105C8Y	Acetylornithine aminotransferase
GUY19_RS18205	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GUY19_RS18225	ENOG4107REN	Carbamoyltransferase
GUY19_RS18240	ENOG4105ETE	Transcriptional regulator (LacI family
GUY19_RS18250	ENOG4105ETE	Transcriptional regulator (LacI family
GUY19_RS18265	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GUY19_RS18280	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GUY19_RS18305	ENOG4105CVR	type I restriction-modification system
GUY19_RS18320	ENOG4105DZR	Type I site-specific deoxyribonuclease
GUY19_RS18370	ENOG4105C28	cystathionine
GUY19_RS18395	ENOG4105EIE	fructose-bisphosphate aldolase
GUY19_RS18400	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GUY19_RS18405	ENOG4105CDV	Ompa motb domain protein
GUY19_RS18415	ENOG4105CDV	Ompa motb domain protein
GUY19_RS18420	ENOG4105CSM	endonuclease III
GUY19_RS18425	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
GUY19_RS18440	ENOG4108Z0R	Transferase
GUY19_RS18445	ENOG4105C37	(CBS) domain
GUY19_RS18450	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GUY19_RS18455	ENOG4105D44	asparaginase
GUY19_RS18460	ENOG4108VVK	transcriptional Regulator, AsnC
GUY19_RS18470	ENOG41067XB	TonB family
GUY19_RS18475	ENOG4105K63	Thioredoxin
GUY19_RS18480	ENOG4105C0B	DNA polymerase III (alpha subunit)
GUY19_RS18525	ENOG4105C1V	Peptidase, M16
GUY19_RS18530	ENOG4105DKP	glycosyl transferase, family 9
GUY19_RS18540	ENOG4107RAQ	aminopeptidase
GUY19_RS18565	ENOG4105DCG	PHP domain protein
GUY19_RS18570	ENOG4105D16	lipopolysaccharide heptosyltransferase i
GUY19_RS18595	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GUY19_RS18600	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GUY19_RS18660	ENOG4108JQC	penicillin-binding protein 1A
GUY19_RS18675	ENOG4105EUJ	GTP cyclohydrolase i
GUY19_RS18695	ENOG4105CD8	aminopeptidase N
GUY19_RS18705	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GUY19_RS18710	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GUY19_RS18715	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GUY19_RS18720	ENOG4105K5M	30s ribosomal protein S16
GUY19_RS18730	ENOG4108YBP	pseudouridine synthase
GUY19_RS18735	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GUY19_RS18745	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
GUY19_RS18755	ENOG4107QX3	carboxylase
GUY19_RS18775	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
GUY19_RS18790	ENOG4105KRF	dihydroneopterin aldolase
GUY19_RS18815	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GUY19_RS18820	ENOG4105DJT	lAO AO transport system ATPase
GUY19_RS18835	ENOG4105P8F	nudix hydrolase
GUY19_RS18870	ENOG4105D4M	Lactamase_B
GUY19_RS18880	ENOG4105MGM	doxx family
GUY19_RS18890	ENOG4105C5H	ABC transporter
GUY19_RS18915	ENOG4105D5P	Methylmalonyl-coA mutase
GUY19_RS18920	ENOG4105CMN	Methylmalonyl-coA mutase
GUY19_RS18930	ENOG4105CGH	5'-nucleotidase
GUY19_RS18935	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GUY19_RS18940	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GUY19_RS18950	ENOG4108Z9K	Osmotically inducible protein
GUY19_RS18965	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GUY19_RS18970	ENOG4105DZP	Membrane-associated zinc metalloprotease
GUY19_RS18980	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GUY19_RS18985	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GUY19_RS18995	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GUY19_RS19000	ENOG410904N	short-chain dehydrogenase reductase
GUY19_RS19010	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS19020	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS19045	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GUY19_RS19055	ENOG4105C19	ABC transporter
GUY19_RS19065	ENOG410853W	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GUY19_RS19090	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GUY19_RS19100	ENOG4105BZU	Histidine kinase
GUY19_RS19110	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GUY19_RS19120	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
GUY19_RS19125	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GUY19_RS19135	ENOG4105HHA	aminodeoxychorismate lyase
GUY19_RS19145	ENOG4107QP3	malate synthase g
GUY19_RS19155	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GUY19_RS19195	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GUY19_RS19210	ENOG4105YB8	TM2 domain containing protein
GUY19_RS19215	ENOG4105C25	Primosomal protein n'
GUY19_RS19220	ENOG4105C7Z	Conserved Protein
GUY19_RS19230	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GUY19_RS19235	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GUY19_RS19240	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
GUY19_RS19250	ENOG4107SFQ	iron-sulfur binding
GUY19_RS19275	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GUY19_RS19280	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GUY19_RS19290	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GUY19_RS19300	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GUY19_RS19315	ENOG4108SJC	Membrane
GUY19_RS19335	ENOG4105ES5	Histidine kinase
GUY19_RS19345	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GUY19_RS19355	ENOG4105E2D	ec 3.2.1.52
GUY19_RS19365	ENOG4105IIU	Aminopeptidase
GUY19_RS19370	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GUY19_RS19385	ENOG4107QP7	CoA-transferase subunit A
GUY19_RS19395	ENOG4105DTN	riboflavin biosynthesis protein ribF
GUY19_RS19400	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GUY19_RS19405	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GUY19_RS19420	ENOG4107RJ9	Cell division protein FtsX
GUY19_RS19430	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GUY19_RS19440	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GUY19_RS19445	ENOG4107SN7	NLP P60 protein
GUY19_RS19455	ENOG4105VZ8	Transcriptional regulator
GUY19_RS19520	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GUY19_RS19530	ENOG4105NWN	ApaG protein
GUY19_RS19535	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GUY19_RS19540	ENOG4105C3F	Signal peptidase i
GUY19_RS19545	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GUY19_RS19555	ENOG4105FA0	parb-like partition protein
GUY19_RS19580	ENOG4105CZ9	Domain of unknown function (DU1801)
GUY19_RS19590	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GUY19_RS19595	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GUY19_RS19605	ENOG4105DEF	Extracellular solute-binding protein, family 5
GUY19_RS19610	ENOG4105E8R	UPF0173 metal-dependent hydrolase
GUY19_RS19615	ENOG4107QJE	Chromosome Partitioning Protein
GUY19_RS19630	ENOG4108JQ1	Dehydrogenase
GUY19_RS19640	ENOG4107VMU	Membrane
GUY19_RS19645	ENOG4107QWG	2-Nitropropane dioxygenase
GUY19_RS19650	ENOG410874W	AraC family transcriptional regulator
GUY19_RS19690	ENOG4105BZU	Histidine kinase
GUY19_RS19700	ENOG4108NEV	two component transcriptional regulator, LytTR family
GUY19_RS19720	ENOG4105CPC	Aldo Keto reductase
GUY19_RS19740	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GUY19_RS19745	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GUY19_RS19775	ENOG4107U91	Rhomboid family
GUY19_RS19800	ENOG4105F32	YngK protein
GUY19_RS19815	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS19820	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GUY19_RS19825	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS19845	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GUY19_RS19960	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
GUY19_RS19970	ENOG4105CB2	alcohol dehydrogenase
GUY19_RS19980	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
GUY19_RS19985	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GUY19_RS19995	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GUY19_RS20000	ENOG4105DQ5	transport system permease protein
GUY19_RS20010	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GUY19_RS20015	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GUY19_RS20020	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GUY19_RS20025	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GUY19_RS20040	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GUY19_RS20050	ENOG41082AN	stage II sporulation protein
GUY19_RS20055	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GUY19_RS20100	ENOG4105CKK	Glycosyl transferase, family 2
GUY19_RS20115	ENOG4108WQH	regulatoR
GUY19_RS20125	ENOG4107QTF	adenylosuccinate lyase
GUY19_RS20130	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GUY19_RS20135	ENOG4105DU1	integral membrane protein, terc
GUY19_RS20140	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GUY19_RS20145	ENOG4105C1Q	protoporphyrinogen oxidase
GUY19_RS20150	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GUY19_RS20170	ENOG4105C75	arginyL-tRNA synthetase
GUY19_RS20175	ENOG4108URH	decarboxylase
GUY19_RS20185	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GUY19_RS20195	ENOG4105BZU	Histidine kinase
GUY19_RS20200	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GUY19_RS20205	ENOG4105BZU	Histidine kinase
GUY19_RS20215	ENOG4105C1J	atp-dependent rna helicase
GUY19_RS20225	ENOG4105D9R	oxidoreductase
GUY19_RS20235	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GUY19_RS20245	ENOG4105C31	Tryptophanyl-tRNA synthetase
GUY19_RS20275	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GUY19_RS20320	ENOG4105C27	TonB-dependent Receptor Plug
GUY19_RS20350	ENOG4105BZU	Histidine kinase
GUY19_RS20355	ENOG4107YB6	acetyltransferase, (GNAT) family
GUY19_RS20370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GUY19_RS20390	ENOG4108HRK	Histidine kinase
GUY19_RS20395	ENOG4108VAC	response regulator
GUY19_RS20415	ENOG4108VAC	response regulator
GUY19_RS20420	ENOG4108HRK	Histidine kinase
GUY19_RS20465	ENOG4108IPT	Naphthoate synthase
GUY19_RS20470	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GUY19_RS20475	ENOG4105E4F	Isochorismate synthase
GUY19_RS20480	ENOG4105KA0	thioesterase Superfamily protein
GUY19_RS20485	ENOG4105CVJ	phosphoglycerate mutase
GUY19_RS20490	ENOG4105C7S	Dehydrogenase
GUY19_RS20500	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GUY19_RS20570	ENOG410635A	Membrane
GUY19_RS20600	ENOG4105C5H	ABC transporter