locus-tag	class	description
JANN_RS00015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JANN_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JANN_RS00065	COG1054	Belongs to the UPF0176 family
JANN_RS00080	COG1335	isochorismatase
JANN_RS00085	COG0668	transmembrane transport
JANN_RS00095	COG1280	lysine exporter protein (LysE YggA)
JANN_RS00100	COG0116	Belongs to the methyltransferase superfamily
JANN_RS00110	COG1115	amino acid carrier protein
JANN_RS00120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JANN_RS00135	COG3609	addiction module antidote protein, CC2985 family
JANN_RS00145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JANN_RS00160	COG2897	thiosulfate sulfurtransferase activity
JANN_RS00165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JANN_RS00170	COG2814	Major facilitator Superfamily
JANN_RS00175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JANN_RS00180	COG0741	lytic transglycosylase activity
JANN_RS00185	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JANN_RS00200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JANN_RS00215	COG0779	Required for maturation of 30S ribosomal subunits
JANN_RS00225	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JANN_RS00255	COG1309	transcriptional regulator
JANN_RS00260	COG0679	Auxin Efflux Carrier
JANN_RS00265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JANN_RS00275	COG2423	ornithine cyclodeaminase activity
JANN_RS00285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JANN_RS00300	COG0285	dihydrofolate synthase activity
JANN_RS00305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JANN_RS00315	COG0129	dihydroxy-acid dehydratase activity
JANN_RS00335	COG0137	argininosuccinate synthase activity
JANN_RS00345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JANN_RS00355	COG0745	RESPONSE REGULATOR receiver
JANN_RS00380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JANN_RS00385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JANN_RS00395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JANN_RS00405	COG0617	tRNA 3'-terminal CCA addition
JANN_RS00410	COG1132	(ABC) transporter
JANN_RS00415	COG1132	(ABC) transporter
JANN_RS00430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JANN_RS00440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JANN_RS00445	COG0142	geranyltranstransferase activity
JANN_RS00450	COG1722	exodeoxyribonuclease VII activity
JANN_RS00455	COG0123	including yeast histone deacetylase and acetoin utilization protein
JANN_RS00460	COG0745	RESPONSE REGULATOR receiver
JANN_RS00465	COG1846	Transcriptional regulator
JANN_RS00480	COG0583	DNA-binding transcription factor activity
JANN_RS00505	COG2814	Major facilitator Superfamily
JANN_RS00525	COG0791	NLP P60 protein
JANN_RS00530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JANN_RS00540	COG0288	reversible hydration of carbon dioxide
JANN_RS00570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JANN_RS00575	COG0513	Belongs to the DEAD box helicase family
JANN_RS00590	COG1840	ABC-type Fe3 transport system, periplasmic component
JANN_RS00615	COG0066	3-isopropylmalate dehydratase activity
JANN_RS00640	COG0473	3-isopropylmalate dehydrogenase activity
JANN_RS00655	COG0697	spore germination
JANN_RS00675	COG1178	ABC-type Fe3 transport system permease component
JANN_RS00680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JANN_RS00685	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JANN_RS00685	COG3264	Mechanosensitive ion channel
JANN_RS00690	COG0028	Belongs to the TPP enzyme family
JANN_RS00705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JANN_RS00705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JANN_RS00710	COG0697	spore germination
JANN_RS00715	COG1562	ergosterol biosynthetic process
JANN_RS00720	COG1233	COG1233 Phytoene dehydrogenase and related
JANN_RS00730	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JANN_RS00735	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JANN_RS00750	COG0156	8-amino-7-oxononanoate synthase activity
JANN_RS00760	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JANN_RS00795	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JANN_RS00800	COG1429	ligase activity, forming nitrogen-metal bonds
JANN_RS00805	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JANN_RS00810	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JANN_RS00830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JANN_RS00835	COG2211	Major facilitator Superfamily
JANN_RS00840	COG0644	oxidoreductase
JANN_RS00845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JANN_RS00855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JANN_RS00890	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JANN_RS00895	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JANN_RS00900	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JANN_RS00905	COG1063	alcohol dehydrogenase
JANN_RS00910	COG0500	methyltransferase
JANN_RS00915	COG0142	geranyltranstransferase activity
JANN_RS00920	COG1233	COG1233 Phytoene dehydrogenase and related
JANN_RS00925	COG5621	secreted hydrolase
JANN_RS00930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JANN_RS00940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JANN_RS00950	COG2840	Smr protein MutS2
JANN_RS00970	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JANN_RS00975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JANN_RS00980	COG0237	dephospho-CoA kinase activity
JANN_RS00985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JANN_RS00990	COG0424	maF-like protein
JANN_RS00995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JANN_RS01000	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JANN_RS01005	COG0445	tRNA wobble uridine modification
JANN_RS01010	COG0357	Ribosomal RNA small subunit methyltransferase G
JANN_RS01025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JANN_RS01030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JANN_RS01035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JANN_RS01040	COG1420	regulation of RNA biosynthetic process
JANN_RS01045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JANN_RS01050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JANN_RS01055	COG0281	malic enzyme
JANN_RS01055	COG0280	phosphate acetyltransferase
JANN_RS01060	COG0484	heat shock protein binding
JANN_RS01065	COG0443	Heat shock 70 kDa protein
JANN_RS01085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JANN_RS01120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JANN_RS01125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JANN_RS01130	COG1137	ATPase activity
JANN_RS01145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JANN_RS01150	COG0582	viral genome integration into host DNA
JANN_RS01175	COG4983	Phage plasmid primase, P4 family domain protein
JANN_RS01250	COG0729	surface antigen
JANN_RS01260	COG1968	undecaprenyl-diphosphatase activity
JANN_RS01285	COG3830	Belongs to the UPF0237 family
JANN_RS01285	COG0560	Phosphoserine phosphatase
JANN_RS01305	COG0577	efflux transmembrane transporter activity
JANN_RS01330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JANN_RS01335	COG0183	Belongs to the thiolase family
JANN_RS01340	COG4953	penicillin-binding protein 1C
JANN_RS01345	COG2373	Large extracellular alpha-helical protein
JANN_RS01350	COG2205	protein histidine kinase activity
JANN_RS01350	COG3437	response regulator, receiver
JANN_RS01350	COG3850	Histidine kinase
JANN_RS01350	COG4999	Histidine kinase
JANN_RS01370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JANN_RS01385	COG3034	peptidoglycan biosynthetic process
JANN_RS01395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JANN_RS01405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JANN_RS01410	COG0010	Belongs to the arginase family
JANN_RS01425	COG0583	DNA-binding transcription factor activity
JANN_RS01440	COG1546	Belongs to the CinA family
JANN_RS01440	COG1058	Belongs to the CinA family
JANN_RS01445	COG1489	DNA binding
JANN_RS01450	COG0024	Methionine aminopeptidase
JANN_RS01455	COG2003	Belongs to the UPF0758 family
JANN_RS01470	COG0653	protein targeting
JANN_RS01475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JANN_RS01480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JANN_RS01485	COG0494	nUDIX hydrolase
JANN_RS01505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JANN_RS01515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JANN_RS01525	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
JANN_RS01530	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JANN_RS01565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS01570	COG0438	transferase activity, transferring glycosyl groups
JANN_RS01585	COG1609	Transcriptional regulator
JANN_RS01595	COG0735	belongs to the Fur family
JANN_RS01600	COG1121	(ABC) transporter
JANN_RS01605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JANN_RS01610	COG1760	l-serine dehydratase
JANN_RS01625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JANN_RS01630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JANN_RS01635	COG2808	Putative FMN-binding domain
JANN_RS01650	COG2153	protein acetylation
JANN_RS01675	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JANN_RS01685	COG4143	(ABC) transporter
JANN_RS01690	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JANN_RS01700	COG3118	belongs to the thioredoxin family
JANN_RS01705	COG0785	Cytochrome C biogenesis protein
JANN_RS01720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JANN_RS01725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JANN_RS01735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JANN_RS01755	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
JANN_RS01780	COG2171	N-acyltransferase activity
JANN_RS01805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JANN_RS01815	COG0557	exoribonuclease II activity
JANN_RS01820	COG2951	lytic endotransglycosylase activity
JANN_RS01850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JANN_RS01860	COG4948	Mandelate Racemase Muconate Lactonizing
JANN_RS01875	COG0435	Glutathione S-transferase
JANN_RS01885	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JANN_RS01910	COG3655	Transcriptional regulator
JANN_RS01925	COG0799	negative regulation of ribosome biogenesis
JANN_RS01930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JANN_RS01935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JANN_RS01945	COG0793	Belongs to the peptidase S41A family
JANN_RS01950	COG0494	nUDIX hydrolase
JANN_RS01990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JANN_RS02005	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JANN_RS02010	COG1194	a g-specific adenine glycosylase
JANN_RS02020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JANN_RS02030	COG1663	tetraacyldisaccharide 4'-kinase activity
JANN_RS02035	COG1519	Transferase
JANN_RS02050	COG0483	inositol monophosphate 1-phosphatase activity
JANN_RS02055	COG0312	modulator of DNA gyrase
JANN_RS02080	COG0625	glutathione transferase activity
JANN_RS02095	COG0495	leucyl-tRNA aminoacylation
JANN_RS02130	COG0745	RESPONSE REGULATOR receiver
JANN_RS02145	COG0596	Alpha beta hydrolase
JANN_RS02150	COG0708	Exodeoxyribonuclease III
JANN_RS02165	COG2835	tetraacyldisaccharide 4'-kinase activity
JANN_RS02170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JANN_RS02180	COG0436	Aminotransferase
JANN_RS02185	COG1674	ftsk spoiiie
JANN_RS02235	COG2154	pterin-4-alpha-carbinolamine dehydratase
JANN_RS02240	COG0678	peroxiredoxin activity
JANN_RS02250	COG0742	ribosomal rna small subunit methyltransferase
JANN_RS02255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JANN_RS02260	COG0514	ATP-dependent DNA helicase (RecQ)
JANN_RS02265	COG3022	response to hydroperoxide
JANN_RS02280	COG0469	pyruvate kinase activity
JANN_RS02295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JANN_RS02300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JANN_RS02305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JANN_RS02310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JANN_RS02310	COG0072	phenylalanine-tRNA ligase activity
JANN_RS02320	COG0625	glutathione transferase activity
JANN_RS02325	COG1970	mechanosensitive ion channel activity
JANN_RS02330	COG0686	Belongs to the AlaDH PNT family
JANN_RS02335	COG1522	sequence-specific DNA binding
JANN_RS02350	COG0746	molybdenum cofactor guanylyltransferase activity
JANN_RS02365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JANN_RS02370	COG0242	peptide deformylase activity
JANN_RS02375	COG0242	peptide deformylase activity
JANN_RS02380	COG0242	peptide deformylase activity
JANN_RS02385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JANN_RS02395	COG2301	Belongs to the HpcH HpaI aldolase family
JANN_RS02405	COG0825	malonyl-CoA metabolic process
JANN_RS02435	COG2884	Cell division ATP-binding protein ftsE
JANN_RS02450	COG0019	diaminopimelate decarboxylase activity
JANN_RS02475	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JANN_RS02480	COG0142	geranyltranstransferase activity
JANN_RS02495	COG0583	DNA-binding transcription factor activity
JANN_RS02515	COG0519	Catalyzes the synthesis of GMP from XMP
JANN_RS02520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JANN_RS02525	COG0165	Argininosuccinate lyase
JANN_RS02530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JANN_RS02540	COG2860	membrane
JANN_RS02550	COG0328	RNA-DNA hybrid ribonuclease activity
JANN_RS02555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JANN_RS02565	COG1280	lysine exporter protein (LysE YggA)
JANN_RS02575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JANN_RS02600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JANN_RS02605	COG1758	RNA polymerase activity
JANN_RS02620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JANN_RS02640	COG0736	holo-[acyl-carrier-protein] synthase activity
JANN_RS02645	COG0681	Belongs to the peptidase S26 family
JANN_RS02650	COG0571	ribonuclease III activity
JANN_RS02660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JANN_RS02675	COG1381	Involved in DNA repair and RecF pathway recombination
JANN_RS02680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JANN_RS02715	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JANN_RS02720	COG0745	RESPONSE REGULATOR receiver
JANN_RS02725	COG2205	protein histidine kinase activity
JANN_RS02735	COG1660	Displays ATPase and GTPase activities
JANN_RS02745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JANN_RS02755	COG1250	3-hydroxyacyl-CoA dehydrogenase
JANN_RS02775	COG1272	protein, Hemolysin III
JANN_RS02785	COG2096	Adenosyltransferase
JANN_RS02795	COG0300	oxidoreductase activity
JANN_RS02805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JANN_RS02815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JANN_RS02850	COG0250	Participates in transcription elongation, termination and antitermination
JANN_RS02860	COG0640	Transcriptional regulator
JANN_RS02865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JANN_RS02870	COG0081	regulation of translation
JANN_RS02875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JANN_RS02880	COG0222	ribosome binding
JANN_RS02885	COG0085	RNA polymerase activity
JANN_RS02890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JANN_RS02925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JANN_RS02930	COG0049	tRNA binding
JANN_RS02935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JANN_RS02940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JANN_RS02955	COG0051	transcription antitermination factor activity, RNA binding
JANN_RS02960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JANN_RS02965	COG0088	Forms part of the polypeptide exit tunnel
JANN_RS02970	COG0089	rRNA binding
JANN_RS02985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JANN_RS02990	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JANN_RS02995	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JANN_RS03000	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JANN_RS03005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JANN_RS03040	COG0255	Belongs to the universal ribosomal protein uL29 family
JANN_RS03045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JANN_RS03050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JANN_RS03055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JANN_RS03060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JANN_RS03065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JANN_RS03070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JANN_RS03075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JANN_RS03080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JANN_RS03085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JANN_RS03090	COG1841	ribosomal large subunit assembly
JANN_RS03100	COG0200	Binds to the 23S rRNA
JANN_RS03110	COG0563	adenylate kinase activity
JANN_RS03120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JANN_RS03125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JANN_RS03130	COG0202	RNA polymerase activity
JANN_RS03135	COG0203	ribosomal protein L17
JANN_RS03145	COG3916	Acyl-homoserine-lactone synthase
JANN_RS03150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JANN_RS03160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JANN_RS03165	COG0564	pseudouridine synthase activity
JANN_RS03170	COG0546	phosphoglycolate phosphatase activity
JANN_RS03180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JANN_RS03185	COG4597	amino acid ABC transporter
JANN_RS03190	COG0765	amino acid transport
JANN_RS03195	COG1126	abc transporter atp-binding protein
JANN_RS03210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JANN_RS03215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JANN_RS03230	COG0706	membrane insertase activity
JANN_RS03245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JANN_RS03250	COG0594	ribonuclease P activity
JANN_RS03270	COG5000	phosphorelay sensor kinase activity
JANN_RS03305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JANN_RS03310	COG2151	metal-sulfur cluster biosynthetic enzyme
JANN_RS03315	COG3396	Phenylacetate-CoA oxygenase
JANN_RS03320	COG3460	Phenylacetate-CoA oxygenase
JANN_RS03325	COG3396	Phenylacetate-CoA oxygenase
JANN_RS03335	COG2050	protein possibly involved in aromatic compounds catabolism
JANN_RS03340	COG2030	dehydratase
JANN_RS03340	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS03350	COG1846	Transcriptional regulator
JANN_RS03375	COG1024	Enoyl-CoA hydratase
JANN_RS03390	COG0183	Belongs to the thiolase family
JANN_RS03395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JANN_RS03425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JANN_RS03430	COG1024	Enoyl-CoA hydratase
JANN_RS03430	COG1250	3-hydroxyacyl-CoA dehydrogenase
JANN_RS03435	COG2124	cytochrome p450
JANN_RS03465	COG0714	Associated with various cellular activities
JANN_RS03500	COG0277	FAD linked oxidase domain protein
JANN_RS03505	COG0277	FAD linked oxidase domain protein
JANN_RS03515	COG0247	lactate metabolic process
JANN_RS03525	COG0071	Belongs to the small heat shock protein (HSP20) family
JANN_RS03535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JANN_RS03550	COG1702	phosphate starvation-inducible protein PhoH
JANN_RS03565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JANN_RS03570	COG1253	flavin adenine dinucleotide binding
JANN_RS03575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JANN_RS03580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JANN_RS03585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JANN_RS03590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JANN_RS03625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JANN_RS03650	COG2003	Belongs to the UPF0758 family
JANN_RS03655	COG0539	negative regulation of cytoplasmic translation
JANN_RS03675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JANN_RS03720	COG0546	phosphoglycolate phosphatase activity
JANN_RS03730	COG1271	oxidase subunit
JANN_RS03735	COG1294	oxidase, subunit
JANN_RS03740	COG1192	Involved in chromosome partitioning
JANN_RS03755	COG0254	rRNA binding
JANN_RS03760	COG0335	large ribosomal subunit rRNA binding
JANN_RS03770	COG0336	Belongs to the RNA methyltransferase TrmD family
JANN_RS03775	COG1131	(ABC) transporter
JANN_RS03780	COG0842	Transport permease protein
JANN_RS03785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JANN_RS03795	COG0228	four-way junction DNA binding
JANN_RS03805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JANN_RS03835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JANN_RS03850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JANN_RS03855	COG0583	DNA-binding transcription factor activity
JANN_RS03875	COG0640	Transcriptional regulator
JANN_RS03885	COG0356	it plays a direct role in the translocation of protons across the membrane
JANN_RS03890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JANN_RS03895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JANN_RS03900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JANN_RS03910	COG3191	aminopeptidase activity
JANN_RS03920	COG0662	Cupin 2, conserved barrel domain protein
JANN_RS03940	COG4172	Belongs to the ABC transporter superfamily
JANN_RS03945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS03965	COG0747	negative chemotaxis
JANN_RS03975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JANN_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS04005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JANN_RS04025	COG0604	alcohol dehydrogenase
JANN_RS04035	COG2937	Belongs to the GPAT DAPAT family
JANN_RS04050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JANN_RS04050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JANN_RS04060	COG0813	purine-nucleoside phosphorylase activity
JANN_RS04070	COG0019	diaminopimelate decarboxylase activity
JANN_RS04130	COG2030	dehydratase
JANN_RS04145	COG2301	Belongs to the HpcH HpaI aldolase family
JANN_RS04155	COG0039	L-malate dehydrogenase activity
JANN_RS04160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JANN_RS04170	COG0045	succinate-CoA ligase (ADP-forming) activity
JANN_RS04220	COG0567	Dehydrogenase, E1 component
JANN_RS04225	COG0508	dehydrogenase complex catalyzes the overall conversion of
JANN_RS04235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JANN_RS04255	COG1802	Transcriptional regulator
JANN_RS04275	COG2304	oxidoreductase activity
JANN_RS04285	COG0730	response to heat
JANN_RS04300	COG4221	oxidoreductase activity
JANN_RS04315	COG3608	succinylglutamate desuccinylase aspartoacylase
JANN_RS04320	COG0006	proline dipeptidase activity
JANN_RS04325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JANN_RS04355	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JANN_RS04360	COG1079	Belongs to the binding-protein-dependent transport system permease family
JANN_RS04380	COG3845	ABC transporter
JANN_RS04385	COG1744	ABC transporter substrate-binding protein PnrA-like
JANN_RS04390	COG0456	acetyltransferase
JANN_RS04390	COG1214	PFAM Peptidase M22, glycoprotease
JANN_RS04405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JANN_RS04410	COG1252	NADH dehydrogenase
JANN_RS04420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JANN_RS04425	COG0179	Fumarylacetoacetate (FAA) hydrolase
JANN_RS04450	COG2080	2 iron, 2 sulfur cluster binding
JANN_RS04455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JANN_RS04455	COG2010	Cytochrome c
JANN_RS04460	COG1802	Transcriptional regulator
JANN_RS04495	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS04500	COG3457	Alanine racemase
JANN_RS04515	COG0583	DNA-binding transcription factor activity
JANN_RS04525	COG0667	Aldo Keto reductase
JANN_RS04530	COG2814	Major facilitator Superfamily
JANN_RS04540	COG2514	catechol 2,3-dioxygenase activity
JANN_RS04555	COG0180	Tryptophanyl-tRNA synthetase
JANN_RS04570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JANN_RS04580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JANN_RS04585	COG0792	nuclease activity
JANN_RS04590	COG0189	ligase activity
JANN_RS04595	COG0606	chelatase, subunit chli
JANN_RS04615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JANN_RS04620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JANN_RS04630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JANN_RS04640	COG0765	amino acid transport
JANN_RS04725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JANN_RS04730	COG1079	Belongs to the binding-protein-dependent transport system permease family
JANN_RS04745	COG4603	Belongs to the binding-protein-dependent transport system permease family
JANN_RS04750	COG3845	ABC transporter
JANN_RS04760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JANN_RS04765	COG2080	2 iron, 2 sulfur cluster binding
JANN_RS04795	COG2271	Major facilitator Superfamily
JANN_RS04805	COG0124	histidyl-tRNA synthetase
JANN_RS04810	COG0124	histidyl-tRNA synthetase
JANN_RS04815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JANN_RS04850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JANN_RS04860	COG5310	Homospermidine synthase
JANN_RS04905	COG0632	four-way junction helicase activity
JANN_RS04910	COG2255	four-way junction helicase activity
JANN_RS04925	COG0824	Thioesterase
JANN_RS04955	COG0823	Involved in the tonB-independent uptake of proteins
JANN_RS04960	COG2885	chlorophyll binding
JANN_RS04970	COG0037	tRNA processing
JANN_RS04975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JANN_RS04985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JANN_RS04995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JANN_RS05010	COG1201	RNA secondary structure unwinding
JANN_RS05015	COG0129	dihydroxy-acid dehydratase activity
JANN_RS05065	COG4964	Belongs to the GSP D family
JANN_RS05090	COG0741	lytic transglycosylase activity
JANN_RS05100	COG1607	acyl-coa hydrolase
JANN_RS05155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JANN_RS05195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JANN_RS05200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JANN_RS05215	COG0583	DNA-binding transcription factor activity
JANN_RS05220	COG0483	inositol monophosphate 1-phosphatase activity
JANN_RS05225	COG1183	phosphatidylcholine synthase activity
JANN_RS05240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JANN_RS05250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JANN_RS05255	COG0287	Prephenate dehydrogenase
JANN_RS05270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JANN_RS05290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JANN_RS05305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JANN_RS05310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JANN_RS05315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JANN_RS05320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JANN_RS05325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JANN_RS05350	COG0596	Alpha beta hydrolase
JANN_RS05360	COG0628	permease
JANN_RS05365	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JANN_RS05370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JANN_RS05375	COG0248	Ppx GppA phosphatase
JANN_RS05380	COG0442	prolyl-tRNA aminoacylation
JANN_RS05405	COG0739	heme binding
JANN_RS05405	COG1388	LysM domain
JANN_RS05415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JANN_RS05420	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JANN_RS05430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JANN_RS05450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS05455	COG0601	transmembrane transport
JANN_RS05470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JANN_RS05475	COG0583	DNA-binding transcription factor activity
JANN_RS05500	COG1862	Preprotein translocase
JANN_RS05505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JANN_RS05510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JANN_RS05520	COG3737	Protein of unknown function (DUF498/DUF598)
JANN_RS05535	COG3739	integral membrane protein
JANN_RS05540	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JANN_RS05555	COG1278	Cold shock
JANN_RS05560	COG1393	Belongs to the ArsC family
JANN_RS05575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JANN_RS05590	COG0640	Transcriptional regulator
JANN_RS05605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JANN_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS05670	COG3243	poly(R)-hydroxyalkanoic acid synthase
JANN_RS05690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JANN_RS05700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JANN_RS05705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JANN_RS05715	COG0174	glutamine synthetase
JANN_RS05720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JANN_RS05720	COG0519	Catalyzes the synthesis of GMP from XMP
JANN_RS05725	COG0174	glutamine synthetase
JANN_RS05750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JANN_RS05785	COG0384	phenazine biosynthesis protein PhzF
JANN_RS05805	COG1960	acyl-CoA dehydrogenase activity
JANN_RS05825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JANN_RS05855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JANN_RS05860	COG0318	PFAM AMP-dependent synthetase and ligase
JANN_RS05870	COG2197	response regulator
JANN_RS05920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JANN_RS05925	COG0277	FAD linked oxidase domain protein
JANN_RS05925	COG0247	lactate metabolic process
JANN_RS05950	COG0697	spore germination
JANN_RS05955	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JANN_RS05960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JANN_RS05970	COG0649	NAD binding
JANN_RS05990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JANN_RS05990	COG3743	rRNA binding
JANN_RS06030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JANN_RS06040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JANN_RS06070	COG0713	ATP synthesis coupled electron transport
JANN_RS06085	COG1007	ATP synthesis coupled electron transport
JANN_RS06095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JANN_RS06105	COG0513	Belongs to the DEAD box helicase family
JANN_RS06120	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JANN_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS06145	COG3842	ATPase activity
JANN_RS06150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JANN_RS06160	COG0805	protein transport
JANN_RS06170	COG3239	Fatty acid desaturase
JANN_RS06175	COG0552	protein localization to endoplasmic reticulum
JANN_RS06195	COG0590	tRNA wobble adenosine to inosine editing
JANN_RS06200	COG3023	N-Acetylmuramoyl-L-alanine amidase
JANN_RS06210	COG0154	amidase activity
JANN_RS06215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JANN_RS06230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JANN_RS06245	COG0670	Belongs to the BI1 family
JANN_RS06255	COG0583	DNA-binding transcription factor activity
JANN_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS06260	COG3321	synthase
JANN_RS06260	COG0604	alcohol dehydrogenase
JANN_RS06265	COG1396	sequence-specific DNA binding
JANN_RS06270	COG0483	inositol monophosphate 1-phosphatase activity
JANN_RS06300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JANN_RS06330	COG1802	Transcriptional regulator
JANN_RS06340	COG0505	Belongs to the CarA family
JANN_RS06345	COG1610	YqeY-like protein
JANN_RS06370	COG0321	lipoyl(octanoyl) transferase activity
JANN_RS06405	COG3002	Belongs to the UPF0753 family
JANN_RS06410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JANN_RS06445	COG3842	ATPase activity
JANN_RS06460	COG1176	ABC-type spermidine putrescine transport system, permease component I
JANN_RS06485	COG1234	tRNA 3'-trailer cleavage
JANN_RS06490	COG0084	hydrolase, TatD family'
JANN_RS06500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JANN_RS06505	COG1686	Belongs to the peptidase S11 family
JANN_RS06530	COG1609	Transcriptional regulator
JANN_RS06540	COG1175	transmembrane transport
JANN_RS06545	COG0395	ABC-type sugar transport system, permease component
JANN_RS06550	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JANN_RS06560	COG1335	isochorismatase
JANN_RS06605	COG1079	Belongs to the binding-protein-dependent transport system permease family
JANN_RS06610	COG4603	Belongs to the binding-protein-dependent transport system permease family
JANN_RS06615	COG3845	ABC transporter
JANN_RS06620	COG0154	amidase activity
JANN_RS06630	COG0402	S-adenosylhomocysteine deaminase activity
JANN_RS06640	COG1959	2 iron, 2 sulfur cluster binding
JANN_RS06705	COG0300	oxidoreductase activity
JANN_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS06790	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JANN_RS06820	COG4638	Rieske (2fe-2S)
JANN_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS06835	COG1609	Transcriptional regulator
JANN_RS06845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JANN_RS06850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JANN_RS06855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JANN_RS06855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS06870	COG0395	ABC-type sugar transport system, permease component
JANN_RS06885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JANN_RS06895	COG2188	Transcriptional regulator
JANN_RS06900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JANN_RS06905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JANN_RS06915	COG1840	ABC-type Fe3 transport system, periplasmic component
JANN_RS06930	COG0483	inositol monophosphate 1-phosphatase activity
JANN_RS06980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JANN_RS06985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JANN_RS07025	COG0410	ABC transporter
JANN_RS07035	COG5441	Belongs to the UPF0261 family
JANN_RS07040	COG0395	ABC-type sugar transport system, permease component
JANN_RS07050	COG1653	transport
JANN_RS07055	COG3842	ATPase activity
JANN_RS07060	COG1802	Transcriptional regulator
JANN_RS07065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JANN_RS07070	COG0647	UMP catabolic process
JANN_RS07080	COG1070	Carbohydrate kinase
JANN_RS07085	COG1609	Transcriptional regulator
JANN_RS07090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JANN_RS07095	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS07100	COG1063	alcohol dehydrogenase
JANN_RS07130	COG0028	Belongs to the TPP enzyme family
JANN_RS07140	COG4948	Mandelate Racemase Muconate Lactonizing
JANN_RS07150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JANN_RS07180	COG0673	inositol 2-dehydrogenase activity
JANN_RS07185	COG0191	fructose-bisphosphate aldolase activity
JANN_RS07195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JANN_RS07200	COG3962	Belongs to the TPP enzyme family
JANN_RS07205	COG0673	inositol 2-dehydrogenase activity
JANN_RS07215	COG0673	inositol 2-dehydrogenase activity
JANN_RS07220	COG1609	Transcriptional regulator
JANN_RS07235	COG1129	ABC transporter
JANN_RS07245	COG3718	enzyme involved in inositol metabolism
JANN_RS07260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JANN_RS07280	COG0179	Fumarylacetoacetate (FAA) hydrolase
JANN_RS07285	COG0625	glutathione transferase activity
JANN_RS07295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JANN_RS07305	COG3302	dmso reductase anchor subunit
JANN_RS07310	COG0437	4 iron, 4 sulfur cluster binding
JANN_RS07315	COG0243	molybdopterin cofactor binding
JANN_RS07320	COG1414	Transcriptional regulator
JANN_RS07335	COG1917	Cupin 2, conserved barrel domain protein
JANN_RS07340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JANN_RS07355	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
JANN_RS07365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JANN_RS07375	COG1609	Transcriptional regulator
JANN_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS07395	COG1609	Transcriptional regulator
JANN_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS07410	COG1082	Xylose isomerase domain protein TIM barrel
JANN_RS07415	COG1879	ABC-type sugar transport system periplasmic component
JANN_RS07420	COG1129	ABC transporter
JANN_RS07425	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS07430	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS07435	COG0673	inositol 2-dehydrogenase activity
JANN_RS07445	COG0673	inositol 2-dehydrogenase activity
JANN_RS07450	COG0251	oxidation-reduction process
JANN_RS07465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS07470	COG0402	S-adenosylhomocysteine deaminase activity
JANN_RS07480	COG2249	NAD(P)H dehydrogenase (quinone) activity
JANN_RS07485	COG2249	NAD(P)H dehydrogenase (quinone) activity
JANN_RS07495	COG1309	transcriptional regulator
JANN_RS07520	COG0463	Glycosyl transferase, family 2
JANN_RS07525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JANN_RS07540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JANN_RS07560	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JANN_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS07570	COG3119	arylsulfatase activity
JANN_RS07580	COG1309	transcriptional regulator
JANN_RS07605	COG4175	Glycine betaine
JANN_RS07610	COG1960	acyl-CoA dehydrogenase activity
JANN_RS07615	COG1960	acyl-CoA dehydrogenase activity
JANN_RS07625	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JANN_RS07635	COG0018	arginyl-trna synthetase
JANN_RS07650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JANN_RS07655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JANN_RS07690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JANN_RS07700	COG0544	peptidyl-prolyl cis-trans isomerase activity
JANN_RS07705	COG1522	sequence-specific DNA binding
JANN_RS07735	COG0583	DNA-binding transcription factor activity
JANN_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS07750	COG0446	pyridine nucleotide-disulphide oxidoreductase
JANN_RS07750	COG1902	pentaerythritol trinitrate reductase activity
JANN_RS07755	COG3938	Belongs to the proline racemase family
JANN_RS07785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JANN_RS07785	COG0784	Response regulator, receiver
JANN_RS07815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JANN_RS07830	COG0582	viral genome integration into host DNA
JANN_RS07840	COG0697	spore germination
JANN_RS07860	COG0583	DNA-binding transcription factor activity
JANN_RS07935	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS07940	COG0318	PFAM AMP-dependent synthetase and ligase
JANN_RS07955	COG2995	paraquat-inducible protein a
JANN_RS07960	COG3008	intermembrane lipid transfer
JANN_RS07960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JANN_RS08000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JANN_RS08005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JANN_RS08020	COG2814	Major facilitator Superfamily
JANN_RS08035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JANN_RS08070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JANN_RS08090	COG1280	lysine exporter protein (LysE YggA)
JANN_RS08170	COG0544	peptidyl-prolyl cis-trans isomerase activity
JANN_RS08200	COG2133	pyrroloquinoline quinone binding
JANN_RS08205	COG0359	binds to the 23S rRNA
JANN_RS08210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JANN_RS08215	COG0360	Binds together with S18 to 16S ribosomal RNA
JANN_RS08225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JANN_RS08240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JANN_RS08250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JANN_RS08255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JANN_RS08270	COG4695	Portal protein
JANN_RS08360	COG1217	gtp-binding protein TYPA
JANN_RS08370	COG0735	belongs to the Fur family
JANN_RS08375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JANN_RS08380	COG0251	oxidation-reduction process
JANN_RS08390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JANN_RS08395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JANN_RS08405	COG0596	Alpha beta hydrolase
JANN_RS08420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JANN_RS08425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JANN_RS08435	COG4948	Mandelate Racemase Muconate Lactonizing
JANN_RS08450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JANN_RS08450	COG2169	Transcriptional regulator
JANN_RS08455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JANN_RS08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JANN_RS08525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JANN_RS08525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JANN_RS08535	COG1187	pseudouridine synthase activity
JANN_RS08550	COG0508	dehydrogenase complex catalyzes the overall conversion of
JANN_RS08560	COG0022	dehydrogenase e1 component
JANN_RS08560	COG0508	dehydrogenase complex catalyzes the overall conversion of
JANN_RS08565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JANN_RS08575	COG3588	fructose-bisphosphate aldolase
JANN_RS08580	COG0126	phosphoglycerate kinase activity
JANN_RS08610	COG2354	Protein conserved in bacteria
JANN_RS08615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JANN_RS08630	COG4221	oxidoreductase activity
JANN_RS08635	COG1268	BioY protein
JANN_RS08650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JANN_RS08690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JANN_RS08700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JANN_RS08715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JANN_RS08730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JANN_RS08740	COG0517	IMP dehydrogenase activity
JANN_RS08740	COG1994	Peptidase M50
JANN_RS08765	COG2204	response regulator
JANN_RS08780	COG0149	triose-phosphate isomerase activity
JANN_RS08810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JANN_RS08815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JANN_RS08820	COG0305	Participates in initiation and elongation during chromosome replication
JANN_RS08825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JANN_RS08830	COG0418	dihydroorotase activity
JANN_RS08840	COG0829	nickel cation binding
JANN_RS08845	COG0831	urea catabolic process
JANN_RS08855	COG0832	Belongs to the urease beta subunit family
JANN_RS08880	COG0804	urea catabolic process
JANN_RS08895	COG0830	nickel cation binding
JANN_RS08900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JANN_RS08925	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JANN_RS08965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JANN_RS08985	COG0175	sulfate reduction
JANN_RS08990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JANN_RS09000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JANN_RS09000	COG1648	precorrin-2 dehydrogenase activity
JANN_RS09005	COG1522	sequence-specific DNA binding
JANN_RS09020	COG0006	proline dipeptidase activity
JANN_RS09030	COG0717	Belongs to the dCTP deaminase family
JANN_RS09045	COG0776	regulation of translation
JANN_RS09050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JANN_RS09055	COG0416	fatty acid biosynthetic process
JANN_RS09060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JANN_RS09090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JANN_RS09095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JANN_RS09100	COG2268	Band 7 protein
JANN_RS09115	COG0148	phosphopyruvate hydratase activity
JANN_RS09140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JANN_RS09160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JANN_RS09165	COG2890	protein-(glutamine-N5) methyltransferase activity
JANN_RS09175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JANN_RS09180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JANN_RS09185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JANN_RS09190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JANN_RS09205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JANN_RS09220	COG2095	MarC family integral membrane protein
JANN_RS09230	COG0488	(ABC) transporter
JANN_RS09240	COG0105	UTP biosynthetic process
JANN_RS09270	COG0006	proline dipeptidase activity
JANN_RS09285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JANN_RS09310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JANN_RS09315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JANN_RS09320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JANN_RS09330	COG2166	iron-sulfur cluster assembly
JANN_RS09335	COG0372	Belongs to the citrate synthase family
JANN_RS09340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JANN_RS09345	COG2333	competence protein COMEC
JANN_RS09345	COG0658	competence protein
JANN_RS09350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JANN_RS09355	COG2326	polyphosphate kinase activity
JANN_RS09385	COG3853	Toxic anion resistance protein (TelA)
JANN_RS09415	COG1469	GTP cyclohydrolase I activity
JANN_RS09430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JANN_RS09435	COG2081	HI0933 family
JANN_RS09465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JANN_RS09470	COG0693	protein deglycase activity
JANN_RS09495	COG0308	aminopeptidase N
JANN_RS09500	COG0415	Belongs to the DNA photolyase family
JANN_RS09505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JANN_RS09510	COG0303	'Molybdopterin
JANN_RS09515	COG0315	cyclic pyranopterin monophosphate synthase activity
JANN_RS09530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JANN_RS09545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JANN_RS09560	COG0629	single-stranded DNA binding
JANN_RS09565	COG0741	lytic transglycosylase activity
JANN_RS09600	COG0440	acetolactate synthase activity
JANN_RS09620	COG0028	Belongs to the TPP enzyme family
JANN_RS09630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JANN_RS09640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS09650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JANN_RS09675	COG1024	Enoyl-CoA hydratase
JANN_RS09680	COG1960	acyl-CoA dehydrogenase activity
JANN_RS09690	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JANN_RS09720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JANN_RS09735	COG0488	(ABC) transporter
JANN_RS09765	COG0187	DNA topoisomerase II activity
JANN_RS09770	COG2814	Major facilitator Superfamily
JANN_RS09790	COG0534	Mate efflux family protein
JANN_RS09795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JANN_RS09805	COG0156	8-amino-7-oxononanoate synthase activity
JANN_RS09815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JANN_RS09825	COG0277	FAD linked oxidase domain protein
JANN_RS09840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JANN_RS09850	COG4989	oxidoreductase activity
JANN_RS09855	COG0837	glucose binding
JANN_RS09860	COG2723	6-phospho-beta-galactosidase activity
JANN_RS09865	COG1609	Transcriptional regulator
JANN_RS09870	COG1653	transport
JANN_RS09875	COG1175	transmembrane transport
JANN_RS09880	COG0395	ABC-type sugar transport system, permease component
JANN_RS09885	COG0366	Alpha amylase catalytic
JANN_RS09890	COG3842	ATPase activity
JANN_RS09905	COG0129	dihydroxy-acid dehydratase activity
JANN_RS09910	COG0800	Aldolase
JANN_RS09930	COG0215	cysteine-tRNA ligase activity
JANN_RS09935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JANN_RS09955	COG2814	Major facilitator Superfamily
JANN_RS09985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JANN_RS09995	COG0166	Belongs to the GPI family
JANN_RS10050	COG0248	Ppx GppA phosphatase
JANN_RS10055	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JANN_RS10080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JANN_RS10085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JANN_RS10095	COG0415	Belongs to the DNA photolyase family
JANN_RS10100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JANN_RS10110	COG0494	nUDIX hydrolase
JANN_RS10120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JANN_RS10120	COG3264	Mechanosensitive ion channel
JANN_RS10125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JANN_RS10155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JANN_RS10160	COG1280	lysine exporter protein (LysE YggA)
JANN_RS10185	COG1522	sequence-specific DNA binding
JANN_RS10205	COG1309	transcriptional regulator
JANN_RS10235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JANN_RS10240	COG2514	catechol 2,3-dioxygenase activity
JANN_RS10245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JANN_RS10255	COG2226	methyltransferase
JANN_RS10300	COG3300	MHYT domain
JANN_RS10300	COG5001	Diguanylate cyclase
JANN_RS10335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JANN_RS10340	COG0179	Fumarylacetoacetate (FAA) hydrolase
JANN_RS10365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS10370	COG0601	transmembrane transport
JANN_RS10405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JANN_RS10440	COG0628	permease
JANN_RS10445	COG1295	ribonuclease BN
JANN_RS10450	COG1877	trehalose-phosphatase activity
JANN_RS10455	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JANN_RS10490	COG2202	Pas domain
JANN_RS10490	COG3920	Histidine kinase
JANN_RS10500	COG1803	Methylglyoxal synthase
JANN_RS10515	COG1175	transmembrane transport
JANN_RS10520	COG0395	ABC-type sugar transport system, permease component
JANN_RS10525	COG3842	ATPase activity
JANN_RS10535	COG0803	Belongs to the bacterial solute-binding protein 9 family
JANN_RS10540	COG1121	(ABC) transporter
JANN_RS10545	COG1321	iron dependent repressor
JANN_RS10545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JANN_RS10550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JANN_RS10555	COG3483	tryptophan 2,3-dioxygenase activity
JANN_RS10565	COG2217	Heavy metal translocating P-type atpase
JANN_RS10575	COG3180	Ammonia monooxygenase
JANN_RS10590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JANN_RS10595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JANN_RS10595	COG3608	succinylglutamate desuccinylase aspartoacylase
JANN_RS10635	COG3608	succinylglutamate desuccinylase aspartoacylase
JANN_RS10640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JANN_RS10650	COG0431	NADPH-dependent FMN reductase
JANN_RS10655	COG4948	Mandelate Racemase Muconate Lactonizing
JANN_RS10660	COG0179	Fumarylacetoacetate (FAA) hydrolase
JANN_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS10670	COG1802	Transcriptional regulator
JANN_RS10685	COG3618	amidohydrolase
JANN_RS10695	COG0434	BtpA family
JANN_RS10715	COG0395	ABC-type sugar transport system, permease component
JANN_RS10720	COG1175	transmembrane transport
JANN_RS10730	COG3842	ATPase activity
JANN_RS10740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JANN_RS10745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JANN_RS10750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JANN_RS10755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JANN_RS10760	COG1120	ATPase activity
JANN_RS10785	COG0811	peptide transport
JANN_RS10795	COG4771	TonB-dependent receptor
JANN_RS10800	COG3720	iron ion transport
JANN_RS10805	COG4558	Periplasmic binding protein
JANN_RS10810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JANN_RS10815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JANN_RS10825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JANN_RS10845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JANN_RS10850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JANN_RS10870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JANN_RS10890	COG0433	COG0433 Predicted ATPase
JANN_RS10895	COG0537	adenosine 5'-monophosphoramidase activity
JANN_RS10900	COG1138	Cytochrome C-type biogenesis protein
JANN_RS10905	COG3088	subunit of a heme lyase
JANN_RS10910	COG1024	Enoyl-CoA hydratase
JANN_RS10925	COG1846	Transcriptional regulator
JANN_RS10985	COG1671	Belongs to the UPF0178 family
JANN_RS10990	COG1160	GTP binding
JANN_RS11000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JANN_RS11010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JANN_RS11020	COG0583	DNA-binding transcription factor activity
JANN_RS11030	COG0730	response to heat
JANN_RS11050	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JANN_RS11060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JANN_RS11075	COG0446	pyridine nucleotide-disulphide oxidoreductase
JANN_RS11075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JANN_RS11105	COG1611	Belongs to the LOG family
JANN_RS11115	COG5265	(ABC) transporter
JANN_RS11155	COG3237	CsbD-like
JANN_RS11250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JANN_RS11250	COG0519	Catalyzes the synthesis of GMP from XMP
JANN_RS11275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JANN_RS11280	COG0840	transmembrane signaling receptor activity
JANN_RS11285	COG2010	Cytochrome c
JANN_RS11295	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JANN_RS11305	COG0004	ammonium transporteR
JANN_RS11310	COG1546	Belongs to the CinA family
JANN_RS11310	COG1058	Belongs to the CinA family
JANN_RS11320	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JANN_RS11320	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JANN_RS11325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JANN_RS11330	COG3852	Histidine kinase
JANN_RS11335	COG2204	response regulator
JANN_RS11340	COG5000	phosphorelay sensor kinase activity
JANN_RS11345	COG2204	response regulator
JANN_RS11355	COG0569	domain protein
JANN_RS11365	COG1923	regulation of RNA biosynthetic process
JANN_RS11370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JANN_RS11375	COG2199	diguanylate cyclase activity
JANN_RS11375	COG2200	EAL domain
JANN_RS11380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JANN_RS11385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JANN_RS11410	COG0523	cobalamin synthesis protein
JANN_RS11415	COG3634	alkyl hydroperoxide reductase activity
JANN_RS11505	COG1846	Transcriptional regulator
JANN_RS11515	COG1228	amidohydrolase
JANN_RS11540	COG3743	rRNA binding
JANN_RS11540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JANN_RS11545	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JANN_RS11555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JANN_RS11560	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JANN_RS11565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JANN_RS11580	COG5002	protein histidine kinase activity
JANN_RS11600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JANN_RS11605	COG0704	Plays a role in the regulation of phosphate uptake
JANN_RS11610	COG0745	RESPONSE REGULATOR receiver
JANN_RS11625	COG0251	oxidation-reduction process
JANN_RS11640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JANN_RS11645	COG2197	response regulator
JANN_RS11665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JANN_RS11670	COG0052	Belongs to the universal ribosomal protein uS2 family
JANN_RS11675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JANN_RS11675	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JANN_RS11680	COG2313	pseudouridylate synthase activity
JANN_RS11690	COG4166	transmembrane transport
JANN_RS11695	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS11730	COG2814	Major facilitator Superfamily
JANN_RS11750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JANN_RS11775	COG2366	antibiotic biosynthetic process
JANN_RS11780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JANN_RS11795	COG2358	TRAP transporter, solute receptor (TAXI family
JANN_RS11815	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JANN_RS11820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JANN_RS11830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JANN_RS11840	COG0010	Belongs to the arginase family
JANN_RS11845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JANN_RS11860	COG3956	TIGRFAM MazG family protein
JANN_RS11875	COG0697	spore germination
JANN_RS11895	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JANN_RS11905	COG2326	polyphosphate kinase activity
JANN_RS11910	COG1309	transcriptional regulator
JANN_RS11915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JANN_RS11930	COG0719	Fe-S assembly protein
JANN_RS11935	COG0396	ATPase activity
JANN_RS11960	COG0719	Fe-S assembly protein
JANN_RS11970	COG1959	2 iron, 2 sulfur cluster binding
JANN_RS11975	COG2945	thiolester hydrolase activity
JANN_RS11985	COG0840	transmembrane signaling receptor activity
JANN_RS11995	COG2838	Isocitrate dehydrogenase
JANN_RS12000	COG0538	isocitrate dehydrogenase activity
JANN_RS12015	COG0121	glutamine amidotransferase
JANN_RS12025	COG1522	sequence-specific DNA binding
JANN_RS12030	COG0604	alcohol dehydrogenase
JANN_RS12035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JANN_RS12065	COG2188	Transcriptional regulator
JANN_RS12100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JANN_RS12110	COG0114	fumarate hydratase activity
JANN_RS12135	COG0785	Cytochrome C biogenesis protein
JANN_RS12140	COG0425	Belongs to the sulfur carrier protein TusA family
JANN_RS12145	COG3842	ATPase activity
JANN_RS12150	COG1177	transmembrane transport
JANN_RS12165	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS12170	COG1129	ABC transporter
JANN_RS12185	COG0583	DNA-binding transcription factor activity
JANN_RS12235	COG1959	2 iron, 2 sulfur cluster binding
JANN_RS12245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JANN_RS12250	COG0625	glutathione transferase activity
JANN_RS12275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JANN_RS12280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JANN_RS12290	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JANN_RS12305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JANN_RS12310	COG1612	heme a metabolic process
JANN_RS12320	COG0352	thiamine-phosphate diphosphorylase activity
JANN_RS12350	COG0194	GDP metabolic process
JANN_RS12355	COG1561	YicC-like family, N-terminal region
JANN_RS12365	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JANN_RS12380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JANN_RS12390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JANN_RS12400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JANN_RS12405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JANN_RS12415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JANN_RS12420	COG0750	zinc metalloprotease
JANN_RS12425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JANN_RS12435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JANN_RS12440	COG0233	cytoplasmic translational termination
JANN_RS12450	COG0528	UMP kinase activity
JANN_RS12455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JANN_RS12465	COG4166	transmembrane transport
JANN_RS12470	COG0601	transmembrane transport
JANN_RS12475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS12490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JANN_RS12495	COG4149	molybdate abc transporter
JANN_RS12500	COG0725	ABC transporter, periplasmic molybdate-binding protein
JANN_RS12505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JANN_RS12520	COG1278	Cold shock
JANN_RS12525	COG0259	pyridoxamine-phosphate oxidase activity
JANN_RS12530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JANN_RS12535	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JANN_RS12545	COG1129	ABC transporter
JANN_RS12560	COG4536	flavin adenine dinucleotide binding
JANN_RS12565	COG4974	Belongs to the 'phage' integrase family
JANN_RS12580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JANN_RS12585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JANN_RS12610	COG1238	metal cluster binding
JANN_RS12615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JANN_RS12620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JANN_RS12640	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JANN_RS12650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JANN_RS12655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JANN_RS12670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JANN_RS12685	COG0482	sulfurtransferase activity
JANN_RS12705	COG0697	spore germination
JANN_RS12725	COG1741	Belongs to the pirin family
JANN_RS12740	COG0406	alpha-ribazole phosphatase activity
JANN_RS12760	COG0726	polysaccharide deacetylase
JANN_RS12770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JANN_RS12780	COG0343	queuine tRNA-ribosyltransferase activity
JANN_RS12800	COG2151	metal-sulfur cluster biosynthetic enzyme
JANN_RS12810	COG0316	Belongs to the HesB IscA family
JANN_RS12825	COG2833	Protein of unknown function (DUF455)
JANN_RS12845	COG0154	amidase activity
JANN_RS12850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JANN_RS12855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JANN_RS12865	COG0860	N-Acetylmuramoyl-L-alanine amidase
JANN_RS12870	COG0436	Aminotransferase
JANN_RS12880	COG1530	ribonuclease E activity
JANN_RS12890	COG2204	response regulator
JANN_RS12900	COG0047	phosphoribosylformylglycinamidine synthase activity
JANN_RS12905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JANN_RS12910	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JANN_RS12920	COG0646	methionine synthase
JANN_RS12920	COG1410	methionine synthase
JANN_RS12935	COG5012	cobalamin binding
JANN_RS12970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JANN_RS12975	COG3383	formate dehydrogenase (NAD+) activity
JANN_RS12990	COG0583	DNA-binding transcription factor activity
JANN_RS13025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS13040	COG4336	lyase activity
JANN_RS13045	COG0583	DNA-binding transcription factor activity
JANN_RS13060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JANN_RS13095	COG3813	Protein conserved in bacteria
JANN_RS13105	COG0656	L-ascorbic acid biosynthetic process
JANN_RS13110	COG3842	ATPase activity
JANN_RS13115	COG0165	Argininosuccinate lyase
JANN_RS13125	COG0395	ABC-type sugar transport system, permease component
JANN_RS13140	COG1940	carbohydrate kinase activity
JANN_RS13140	COG1846	Transcriptional regulator
JANN_RS13155	COG3347	Dehydrogenase
JANN_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS13170	COG1129	ABC transporter
JANN_RS13175	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS13180	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS13185	COG3254	rhamnose metabolic process
JANN_RS13200	COG3257	ureidoglycine aminohydrolase activity
JANN_RS13205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JANN_RS13210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JANN_RS13215	COG3616	Alanine racemase, N-terminal domain
JANN_RS13220	COG2423	ornithine cyclodeaminase activity
JANN_RS13230	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JANN_RS13245	COG0583	DNA-binding transcription factor activity
JANN_RS13270	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS13315	COG0596	Alpha beta hydrolase
JANN_RS13350	COG1309	transcriptional regulator
JANN_RS13365	COG3750	Belongs to the UPF0335 family
JANN_RS13375	COG0405	Gamma-glutamyltransferase
JANN_RS13390	COG3842	ATPase activity
JANN_RS13425	COG4133	protoheme IX ABC transporter activity
JANN_RS13430	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JANN_RS13435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JANN_RS13440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JANN_RS13445	COG1846	Transcriptional regulator
JANN_RS13475	COG0395	ABC-type sugar transport system, permease component
JANN_RS13505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JANN_RS13525	COG1793	dna ligase
JANN_RS13525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JANN_RS13535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JANN_RS13565	COG1490	D-aminoacyl-tRNA deacylase activity
JANN_RS13570	COG2308	Evidence 4 Homologs of previously reported genes of
JANN_RS13590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JANN_RS13600	COG0542	response to heat
JANN_RS13625	COG0501	Belongs to the peptidase M48B family
JANN_RS13655	COG5002	protein histidine kinase activity
JANN_RS13685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JANN_RS13690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS13695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS13730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JANN_RS13735	COG1309	transcriptional regulator
JANN_RS13760	COG0439	Biotin carboxylase
JANN_RS13765	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JANN_RS13775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JANN_RS13785	COG2873	o-acetylhomoserine
JANN_RS13795	COG2239	Acts as a magnesium transporter
JANN_RS13800	COG0402	S-adenosylhomocysteine deaminase activity
JANN_RS13805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JANN_RS13810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JANN_RS13820	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JANN_RS13825	COG3409	Peptidoglycan-binding domain 1 protein
JANN_RS13825	COG3773	Cell wall hydrolase
JANN_RS13830	COG0574	Belongs to the PEP-utilizing enzyme family
JANN_RS13830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JANN_RS13835	COG0751	glycine-tRNA ligase activity
JANN_RS13845	COG0752	glycyl-tRNA synthetase alpha subunit
JANN_RS13875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JANN_RS13920	COG0497	DNA recombination
JANN_RS13925	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JANN_RS13935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JANN_RS13940	COG0849	cell division
JANN_RS13945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JANN_RS13950	COG1181	Belongs to the D-alanine--D-alanine ligase family
JANN_RS13955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JANN_RS13980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JANN_RS13985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JANN_RS14000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JANN_RS14005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JANN_RS14010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JANN_RS14015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JANN_RS14030	COG0275	rRNA processing
JANN_RS14040	COG0489	protein tyrosine kinase activity
JANN_RS14075	COG1304	FMN binding
JANN_RS14090	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JANN_RS14105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JANN_RS14135	COG0131	Imidazoleglycerol-phosphate dehydratase
JANN_RS14140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JANN_RS14155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JANN_RS14170	COG0107	imidazoleglycerol-phosphate synthase activity
JANN_RS14175	COG0140	phosphoribosyl-ATP diphosphatase activity
JANN_RS14200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JANN_RS14205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JANN_RS14215	COG1984	allophanate hydrolase subunit 2
JANN_RS14230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JANN_RS14235	COG0740	serine-type endopeptidase activity
JANN_RS14250	COG1960	acyl-CoA dehydrogenase activity
JANN_RS14260	COG1960	acyl-CoA dehydrogenase activity
JANN_RS14300	COG0589	response to stress
JANN_RS14315	COG0601	transmembrane transport
JANN_RS14320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS14330	COG4172	Belongs to the ABC transporter superfamily
JANN_RS14345	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JANN_RS14390	COG0745	RESPONSE REGULATOR receiver
JANN_RS14395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JANN_RS14410	COG0745	RESPONSE REGULATOR receiver
JANN_RS14425	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JANN_RS14430	COG0028	Belongs to the TPP enzyme family
JANN_RS14440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JANN_RS14450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JANN_RS14470	COG3454	Phosphonate metabolism
JANN_RS14475	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JANN_RS14485	COG2188	Transcriptional regulator
JANN_RS14490	COG0270	DNA (cytosine-5-)-methyltransferase activity
JANN_RS14530	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JANN_RS14535	COG2951	lytic endotransglycosylase activity
JANN_RS14540	COG1530	ribonuclease E activity
JANN_RS14545	COG0424	maF-like protein
JANN_RS14555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JANN_RS14585	COG2358	TRAP transporter, solute receptor (TAXI family
JANN_RS14605	COG5328	Belongs to the UPF0262 family
JANN_RS14610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JANN_RS14630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JANN_RS14685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JANN_RS14715	COG1653	transport
JANN_RS14720	COG1175	transmembrane transport
JANN_RS14760	COG3214	Protein conserved in bacteria
JANN_RS14765	COG0318	PFAM AMP-dependent synthetase and ligase
JANN_RS14770	COG1132	(ABC) transporter
JANN_RS14785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JANN_RS14785	COG0519	Catalyzes the synthesis of GMP from XMP
JANN_RS14795	COG0174	glutamine synthetase
JANN_RS14800	COG5001	Diguanylate cyclase
JANN_RS14810	COG1648	precorrin-2 dehydrogenase activity
JANN_RS14810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JANN_RS14815	COG1797	cobyrinic acid a,c-diamide synthase activity
JANN_RS14820	COG2875	Belongs to the precorrin methyltransferase family
JANN_RS14835	COG2099	Precorrin-6x reductase
JANN_RS14890	COG1492	cobalamin metabolic process
JANN_RS14895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JANN_RS14905	COG0583	DNA-binding transcription factor activity
JANN_RS14935	COG0625	glutathione transferase activity
JANN_RS15005	COG0737	Belongs to the 5'-nucleotidase family
JANN_RS15025	COG0534	Mate efflux family protein
JANN_RS15050	COG1960	acyl-CoA dehydrogenase activity
JANN_RS15080	COG0183	Belongs to the thiolase family
JANN_RS15100	COG0318	PFAM AMP-dependent synthetase and ligase
JANN_RS15120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JANN_RS15125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JANN_RS15130	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JANN_RS15140	COG0295	cytidine deaminase activity
JANN_RS15145	COG5002	protein histidine kinase activity
JANN_RS15145	COG2198	Histidine kinase
JANN_RS15145	COG0784	Response regulator, receiver
JANN_RS15150	COG0281	malic enzyme
JANN_RS15150	COG0280	phosphate acetyltransferase
JANN_RS15155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JANN_RS15160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JANN_RS15180	COG3239	Fatty acid desaturase
JANN_RS15210	COG1335	isochorismatase
JANN_RS15250	COG2002	toxin-antitoxin pair type II binding
JANN_RS15395	COG3707	response regulator
JANN_RS15400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JANN_RS15400	COG1116	anion transmembrane transporter activity
JANN_RS15405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JANN_RS15405	COG1116	anion transmembrane transporter activity
JANN_RS15410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS15415	COG1116	anion transmembrane transporter activity
JANN_RS15420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JANN_RS15425	COG2146	nitrite reductase [NAD(P)H] activity
JANN_RS15430	COG0243	molybdopterin cofactor binding
JANN_RS15435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JANN_RS15440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JANN_RS15440	COG1648	precorrin-2 dehydrogenase activity
JANN_RS15455	COG4166	transmembrane transport
JANN_RS15460	COG0601	transmembrane transport
JANN_RS15465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS15490	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS15495	COG1129	ABC transporter
JANN_RS15500	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS15520	COG1850	ribulose-bisphosphate carboxylase activity
JANN_RS15550	COG1960	acyl-CoA dehydrogenase activity
JANN_RS15555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JANN_RS15565	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS15570	COG1177	transmembrane transport
JANN_RS15575	COG1176	ABC-type spermidine putrescine transport system, permease component I
JANN_RS15580	COG3842	ATPase activity
JANN_RS15590	COG2204	response regulator
JANN_RS15605	COG0251	oxidation-reduction process
JANN_RS15610	COG0022	dehydrogenase e1 component
JANN_RS15635	COG2197	response regulator
JANN_RS15640	COG1879	ABC-type sugar transport system periplasmic component
JANN_RS15645	COG1129	ABC transporter
JANN_RS15650	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS15660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JANN_RS15665	COG1609	Transcriptional regulator
JANN_RS15670	COG1172	Belongs to the binding-protein-dependent transport system permease family
JANN_RS15675	COG1129	ABC transporter
JANN_RS15685	COG2207	Transcriptional regulator
JANN_RS15700	COG2207	Transcriptional regulator
JANN_RS15715	COG1280	lysine exporter protein (LysE YggA)
JANN_RS15725	COG1733	regulation of RNA biosynthetic process
JANN_RS15745	COG1136	(ABC) transporter
JANN_RS15770	COG0366	Alpha amylase catalytic
JANN_RS15775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JANN_RS15780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JANN_RS15785	COG0297	glycogen (starch) synthase activity
JANN_RS15795	COG0033	Phosphoglucomutase
JANN_RS15800	COG0058	SHG alpha-glucan phosphorylase activity
JANN_RS15805	COG0318	PFAM AMP-dependent synthetase and ligase
JANN_RS15810	COG0028	Belongs to the TPP enzyme family
JANN_RS15815	COG0069	glutamate synthase activity
JANN_RS15840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JANN_RS15925	COG0667	Aldo Keto reductase
JANN_RS15940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JANN_RS15945	COG0277	FAD linked oxidase domain protein
JANN_RS15955	COG0612	Peptidase, M16
JANN_RS15965	COG3346	SURF1 family
JANN_RS15975	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JANN_RS15985	COG0109	protoheme IX farnesyltransferase activity
JANN_RS15995	COG0312	modulator of DNA gyrase
JANN_RS16005	COG0758	DNA mediated transformation
JANN_RS16015	COG1754	DNA topoisomerase type I activity
JANN_RS16015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JANN_RS16035	COG0346	lactoylglutathione lyase activity
JANN_RS16040	COG0745	RESPONSE REGULATOR receiver
JANN_RS16045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JANN_RS16065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JANN_RS16075	COG0330	HflC and HflK could
JANN_RS16080	COG0330	HflC and HflK could
JANN_RS16090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JANN_RS16110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JANN_RS16120	COG0504	CTP synthase activity
JANN_RS16135	COG0546	phosphoglycolate phosphatase activity
JANN_RS16140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JANN_RS16160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JANN_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS16210	COG1073	alpha beta
JANN_RS16215	COG2943	transferase activity, transferring hexosyl groups
JANN_RS16220	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JANN_RS16235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JANN_RS16240	COG0028	Belongs to the TPP enzyme family
JANN_RS16245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JANN_RS16250	COG1280	lysine exporter protein (LysE YggA)
JANN_RS16255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JANN_RS16260	COG0659	secondary active sulfate transmembrane transporter activity
JANN_RS16280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JANN_RS16320	COG5001	Diguanylate cyclase
JANN_RS16320	COG3300	MHYT domain
JANN_RS16365	COG0582	viral genome integration into host DNA
JANN_RS16375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JANN_RS16385	COG1176	ABC-type spermidine putrescine transport system, permease component I
JANN_RS16390	COG1176	ABC-type spermidine putrescine transport system, permease component I
JANN_RS16395	COG3842	ATPase activity
JANN_RS16400	COG0402	S-adenosylhomocysteine deaminase activity
JANN_RS16415	COG1473	amidohydrolase
JANN_RS16420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JANN_RS16430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JANN_RS16435	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JANN_RS16440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS16440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JANN_RS16450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JANN_RS16460	COG1228	amidohydrolase
JANN_RS16470	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JANN_RS16480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JANN_RS16510	COG1070	Carbohydrate kinase
JANN_RS16520	COG1414	Transcriptional regulator
JANN_RS16540	COG3119	arylsulfatase activity
JANN_RS16625	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JANN_RS16645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JANN_RS16660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JANN_RS16670	COG1473	amidohydrolase
JANN_RS16675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JANN_RS16685	COG0444	Belongs to the ABC transporter superfamily
JANN_RS16690	COG4608	Belongs to the ABC transporter superfamily
JANN_RS16710	COG0601	transmembrane transport
JANN_RS16715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS16725	COG1570	exodeoxyribonuclease VII activity
JANN_RS16735	COG0151	Belongs to the GarS family
JANN_RS16750	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JANN_RS16755	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JANN_RS16765	COG1329	Transcriptional regulator
JANN_RS16770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JANN_RS16775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JANN_RS16785	COG0457	Tetratricopeptide repeat
JANN_RS16795	COG2267	carboxylic ester hydrolase activity
JANN_RS16800	COG1136	(ABC) transporter
JANN_RS16845	COG1435	thymidine kinase activity
JANN_RS16860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JANN_RS16865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JANN_RS16890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JANN_RS16900	COG1496	oxidoreductase activity
JANN_RS16910	COG1522	sequence-specific DNA binding
JANN_RS16915	COG0492	ferredoxin-NADP+ reductase activity
JANN_RS16925	COG2046	Belongs to the sulfate adenylyltransferase family
JANN_RS16925	COG0529	Catalyzes the synthesis of activated sulfate
JANN_RS16985	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JANN_RS16990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JANN_RS17010	COG3454	Phosphonate metabolism
JANN_RS17015	COG0459	protein refolding
JANN_RS17020	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JANN_RS17025	COG0840	transmembrane signaling receptor activity
JANN_RS17030	COG1227	inorganic diphosphatase activity
JANN_RS17045	COG2030	dehydratase
JANN_RS17050	COG0196	riboflavin kinase activity
JANN_RS17055	COG2983	Belongs to the UPF0260 family
JANN_RS17060	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JANN_RS17060	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JANN_RS17075	COG4770	biotin carboxylase activity
JANN_RS17100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JANN_RS17105	COG2814	Major facilitator Superfamily
JANN_RS17110	COG1396	sequence-specific DNA binding
JANN_RS17110	COG3800	Transcriptional regulator
JANN_RS17130	COG0217	transcriptional regulatory protein
JANN_RS17135	COG0490	domain, Protein
JANN_RS17135	COG0471	metal ion transport
JANN_RS17145	COG3273	potassium ion transport
JANN_RS17145	COG0471	metal ion transport
JANN_RS17155	COG1692	metallophosphoesterase
JANN_RS17175	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JANN_RS17235	COG0564	pseudouridine synthase activity
JANN_RS17270	COG0640	Transcriptional regulator
JANN_RS17295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JANN_RS17300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JANN_RS17305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JANN_RS17305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JANN_RS17340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JANN_RS17340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JANN_RS17345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JANN_RS17355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JANN_RS17400	COG0481	GTPase activity
JANN_RS17430	COG1741	Belongs to the pirin family
JANN_RS17440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JANN_RS17465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JANN_RS17470	COG4311	Sarcosine oxidase, delta subunit
JANN_RS17475	COG0446	pyridine nucleotide-disulphide oxidoreductase
JANN_RS17475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JANN_RS17485	COG0358	DNA primase activity
JANN_RS17490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JANN_RS17500	COG3654	unkown
JANN_RS17520	COG1703	isobutyryl-CoA mutase activity
JANN_RS17525	COG1643	Atp-dependent helicase
JANN_RS17545	COG0101	tRNA pseudouridine synthase activity
JANN_RS17550	COG3106	COG3106 Predicted ATPase
JANN_RS17555	COG3768	UPF0283 membrane protein
JANN_RS17575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JANN_RS17580	COG0625	glutathione transferase activity
JANN_RS17590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JANN_RS17595	COG0354	folic acid binding
JANN_RS17600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JANN_RS17605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JANN_RS17630	COG0525	valine-tRNA ligase activity
JANN_RS17635	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JANN_RS17640	COG0596	Alpha beta hydrolase
JANN_RS17645	COG0693	protein deglycase activity
JANN_RS17665	COG1733	regulation of RNA biosynthetic process
JANN_RS17670	COG2084	Dehydrogenase
JANN_RS17715	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JANN_RS17715	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JANN_RS17715	COG0506	proline dehydrogenase activity
JANN_RS17720	COG1522	sequence-specific DNA binding
JANN_RS17725	COG0579	oxidoreductase
JANN_RS17730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JANN_RS17740	COG3971	2-oxopent-4-enoate hydratase activity
JANN_RS17745	COG0179	Fumarylacetoacetate (FAA) hydrolase
JANN_RS17760	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS17775	COG5441	Belongs to the UPF0261 family
JANN_RS17780	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS17805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JANN_RS17810	COG1234	tRNA 3'-trailer cleavage
JANN_RS17825	COG4585	Histidine kinase
JANN_RS17840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS17965	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JANN_RS17970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JANN_RS17975	COG0569	domain protein
JANN_RS17985	COG0626	cystathionine gamma-synthase activity
JANN_RS17990	COG1653	transport
JANN_RS18000	COG0395	ABC-type sugar transport system, permease component
JANN_RS18005	COG3842	ATPase activity
JANN_RS18010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JANN_RS18015	COG1295	ribonuclease BN
JANN_RS18055	COG0784	Response regulator, receiver
JANN_RS18060	COG2116	formate transmembrane transporter activity
JANN_RS18070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JANN_RS18140	COG0012	GTP binding
JANN_RS18145	COG0534	Mate efflux family protein
JANN_RS18155	COG0159	tryptophan synthase activity
JANN_RS18160	COG0776	regulation of translation
JANN_RS18170	COG0135	phosphoribosylanthranilate isomerase activity
JANN_RS18180	COG0133	tryptophan synthase activity
JANN_RS18195	COG0193	aminoacyl-tRNA hydrolase activity
JANN_RS18215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JANN_RS18225	COG1304	FMN binding
JANN_RS18250	COG0556	nucleotide-excision repair
JANN_RS18270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JANN_RS18325	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JANN_RS18340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JANN_RS18345	COG0509	glycine decarboxylation via glycine cleavage system
JANN_RS18350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JANN_RS18350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JANN_RS18365	COG1278	Cold shock
JANN_RS18375	COG0488	(ABC) transporter
JANN_RS18385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JANN_RS18395	COG2027	D-alanyl-D-alanine carboxypeptidase
JANN_RS18410	COG0534	Mate efflux family protein
JANN_RS18420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JANN_RS18445	COG3046	protein related to deoxyribodipyrimidine photolyase
JANN_RS18480	COG0768	penicillin binding
JANN_RS18485	COG0772	Belongs to the SEDS family
JANN_RS18490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JANN_RS18500	COG1573	uracil-dna glycosylase
JANN_RS18515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JANN_RS18545	COG0438	transferase activity, transferring glycosyl groups
JANN_RS18590	COG4235	cytochrome complex assembly
JANN_RS18605	COG1858	cytochrome C peroxidase
JANN_RS18625	COG1414	Transcriptional regulator
JANN_RS18655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JANN_RS18660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JANN_RS18675	COG4181	ATPase activity
JANN_RS18690	COG1320	monovalent cation:proton antiporter activity
JANN_RS18695	COG2212	antiporter activity
JANN_RS18700	COG1863	multisubunit Na H antiporter MnhE subunit
JANN_RS18705	COG0651	ATP synthesis coupled electron transport
JANN_RS18710	COG1006	Multisubunit Na H antiporter MnhC subunit
JANN_RS18715	COG2111	Na H antiporter
JANN_RS18720	COG2111	Na H antiporter
JANN_RS18720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JANN_RS18725	COG0583	DNA-binding transcription factor activity
JANN_RS18730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JANN_RS18735	COG0583	DNA-binding transcription factor activity
JANN_RS18740	COG0395	ABC-type sugar transport system, permease component
JANN_RS18760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JANN_RS18820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JANN_RS18820	COG2111	Na H antiporter
JANN_RS18825	COG1006	Multisubunit Na H antiporter MnhC subunit
JANN_RS18830	COG0651	ATP synthesis coupled electron transport
JANN_RS18840	COG2212	antiporter activity
JANN_RS18845	COG1320	monovalent cation:proton antiporter activity
JANN_RS18910	COG2124	cytochrome p450
JANN_RS18920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JANN_RS18965	COG0583	DNA-binding transcription factor activity
JANN_RS18980	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS18985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JANN_RS18990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JANN_RS18995	COG1024	Enoyl-CoA hydratase
JANN_RS19000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JANN_RS19005	COG3976	FMN-binding domain protein
JANN_RS19005	COG1053	succinate dehydrogenase
JANN_RS19010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS19015	COG1116	anion transmembrane transporter activity
JANN_RS19025	COG0583	DNA-binding transcription factor activity
JANN_RS19040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JANN_RS19045	COG0066	3-isopropylmalate dehydratase activity
JANN_RS19050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JANN_RS19055	COG2188	Transcriptional regulator
JANN_RS19115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JANN_RS19120	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS19125	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19135	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JANN_RS19140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS19155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JANN_RS19160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JANN_RS19180	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19220	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS19230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS19260	COG1737	Transcriptional regulator
JANN_RS19265	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JANN_RS19270	COG0747	negative chemotaxis
JANN_RS19280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS19285	COG4172	Belongs to the ABC transporter superfamily
JANN_RS19295	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JANN_RS19300	COG0583	DNA-binding transcription factor activity
JANN_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19330	COG0747	negative chemotaxis
JANN_RS19340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS19355	COG1917	Cupin 2, conserved barrel domain protein
JANN_RS19355	COG2169	Transcriptional regulator
JANN_RS19360	COG1960	acyl-CoA dehydrogenase activity
JANN_RS19370	COG1024	Enoyl-CoA hydratase
JANN_RS19375	COG3246	L-lysine catabolic process to acetate
JANN_RS19385	COG0824	Thioesterase
JANN_RS19385	COG1250	3-hydroxyacyl-CoA dehydrogenase
JANN_RS19410	COG0800	Aldolase
JANN_RS19415	COG3734	2-keto-3-deoxy-galactonokinase
JANN_RS19420	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19430	COG0395	ABC-type sugar transport system, permease component
JANN_RS19435	COG1175	transmembrane transport
JANN_RS19445	COG1414	Transcriptional regulator
JANN_RS19460	COG1091	dTDP-4-dehydrorhamnose reductase activity
JANN_RS19465	COG1088	dTDP-glucose 4,6-dehydratase activity
JANN_RS19475	COG0181	hydroxymethylbilane synthase activity
JANN_RS19480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JANN_RS19485	COG0438	transferase activity, transferring glycosyl groups
JANN_RS19490	COG0408	coproporphyrinogen oxidase activity
JANN_RS19495	COG1686	Belongs to the peptidase S11 family
JANN_RS19515	COG0348	domain, Protein
JANN_RS19520	COG2010	Cytochrome c
JANN_RS19540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JANN_RS19545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JANN_RS19550	COG4172	Belongs to the ABC transporter superfamily
JANN_RS19555	COG4239	(ABC) transporter, permease
JANN_RS19560	COG4174	ABC transporter (Permease)
JANN_RS19565	COG4166	transmembrane transport
JANN_RS19570	COG3474	cytochrome
JANN_RS19575	COG1605	Chorismate mutase
JANN_RS19575	COG0077	Prephenate dehydratase
JANN_RS19585	COG0737	Belongs to the 5'-nucleotidase family
JANN_RS19590	COG2816	NAD+ diphosphatase activity
JANN_RS19605	COG2321	neutral zinc metallopeptidase
JANN_RS19610	COG1162	GTPase activity
JANN_RS19640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JANN_RS19665	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19670	COG2813	Specifically methylates the guanine in position
JANN_RS19675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JANN_RS19690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JANN_RS19705	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JANN_RS19725	COG1960	acyl-CoA dehydrogenase activity
JANN_RS19730	COG0009	L-threonylcarbamoyladenylate synthase
JANN_RS19735	COG1678	Uncharacterized ACR, COG1678
JANN_RS19745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JANN_RS19755	COG0521	Mo-molybdopterin cofactor biosynthetic process
JANN_RS19760	COG1573	uracil-dna glycosylase
JANN_RS19770	COG0540	Belongs to the ATCase OTCase family
JANN_RS19790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JANN_RS19800	COG3152	Membrane
JANN_RS19825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JANN_RS19840	COG0314	molybdopterin synthase activity
JANN_RS19850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JANN_RS19855	COG0322	excinuclease ABC activity
JANN_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JANN_RS19875	COG0616	signal peptide processing
JANN_RS19900	COG1609	Transcriptional regulator
JANN_RS19915	COG1028	Short-chain dehydrogenase reductase Sdr
JANN_RS19925	COG3842	ATPase activity
JANN_RS19930	COG0395	ABC-type sugar transport system, permease component
JANN_RS19935	COG1175	transmembrane transport
JANN_RS19940	COG1653	transport
JANN_RS19950	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS19965	COG0673	inositol 2-dehydrogenase activity
JANN_RS19970	COG3842	ATPase activity
JANN_RS19975	COG0395	ABC-type sugar transport system, permease component
JANN_RS19980	COG1175	transmembrane transport
JANN_RS19995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JANN_RS20000	COG1116	anion transmembrane transporter activity
JANN_RS20010	COG1414	Transcriptional regulator
JANN_RS20025	COG0583	DNA-binding transcription factor activity
JANN_RS20050	COG0765	amino acid transport
JANN_RS20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JANN_RS20060	COG0765	amino acid transport
JANN_RS20075	COG0534	Mate efflux family protein
JANN_RS20090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JANN_RS20105	COG1053	succinate dehydrogenase
JANN_RS20115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JANN_RS20190	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JANN_RS20200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JANN_RS20210	COG0069	glutamate synthase activity
JANN_RS20215	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JANN_RS20220	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JANN_RS20245	COG0284	orotidine-5'-phosphate decarboxylase activity
JANN_RS20275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JANN_RS20290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JANN_RS20415	COG1595	DNA-templated transcription, initiation
JANN_RS20420	COG3806	Anti-sigma factor
JANN_RS20435	COG0564	pseudouridine synthase activity
JANN_RS20445	COG0450	alkyl hydroperoxide reductase
JANN_RS20455	COG1376	ErfK ybiS ycfS ynhG family protein
JANN_RS20460	COG1185	polyribonucleotide nucleotidyltransferase activity
JANN_RS20470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JANN_RS20480	COG0596	Alpha beta hydrolase
JANN_RS20490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JANN_RS20500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JANN_RS20505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JANN_RS20520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JANN_RS20520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JANN_RS20530	COG0138	bifunctional purine biosynthesis protein purh
JANN_RS20535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JANN_RS20545	COG0612	Peptidase, M16
JANN_RS20550	COG0612	Peptidase, M16
JANN_RS20555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JANN_RS20585	COG0405	Gamma-glutamyltransferase
JANN_RS20595	COG0347	Belongs to the P(II) protein family
JANN_RS20600	COG0004	ammonium transporteR
JANN_RS20610	COG1999	signal sequence binding
JANN_RS20620	COG2205	protein histidine kinase activity
JANN_RS20625	COG0802	atpase or kinase
JANN_RS20630	COG3178	'Phosphotransferase
JANN_RS20635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JANN_RS20645	COG1074	ATP-dependent DNA helicase activity
JANN_RS20655	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JANN_RS20670	COG0583	DNA-binding transcription factor activity
JANN_RS20685	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JANN_RS20690	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JANN_RS20715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JANN_RS20720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JANN_RS20760	COG3842	ATPase activity
JANN_RS20765	COG0395	ABC-type sugar transport system, permease component
JANN_RS20770	COG1175	transmembrane transport
JANN_RS20790	COG1132	(ABC) transporter
JANN_RS20830	COG0395	ABC-type sugar transport system, permease component
JANN_RS20840	COG3842	ATPase activity
JANN_RS20845	COG3842	ATPase activity
JANN_RS20860	COG3833	ABC-type maltose transport systems, permease component
JANN_RS20870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JANN_RS20895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JANN_RS20915	COG0346	lactoylglutathione lyase activity
JANN_RS20920	COG0436	Aminotransferase
JANN_RS20925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JANN_RS20955	COG0436	Aminotransferase
JANN_RS20965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JANN_RS20970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JANN_RS20975	COG0601	transmembrane transport
JANN_RS20980	COG0444	Belongs to the ABC transporter superfamily
JANN_RS20990	COG1802	Transcriptional regulator
JANN_RS20995	COG4166	transmembrane transport
JANN_RS21005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JANN_RS21015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JANN_RS21050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JANN_RS21070	COG5001	Diguanylate cyclase
JANN_RS21070	COG3300	MHYT domain
JANN_RS21075	COG1473	amidohydrolase
JANN_RS21080	COG0006	proline dipeptidase activity
JANN_RS21095	COG2267	carboxylic ester hydrolase activity
JANN_RS21100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JANN_RS21105	COG1012	belongs to the aldehyde dehydrogenase family
JANN_RS21125	COG0583	DNA-binding transcription factor activity
JANN_RS21140	COG3485	protocatechuate 3,4-dioxygenase
JANN_RS21145	COG3485	protocatechuate 3,4-dioxygenase
JANN_RS21165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JANN_RS21185	COG1360	Flagellar Motor Protein
JANN_RS21190	COG1749	Flagellar hook protein flgE
JANN_RS21205	COG1706	bacterial-type flagellum-dependent cell motility
JANN_RS21210	COG1338	Plays a role in the flagellum-specific transport system
JANN_RS21225	COG1766	The M ring may be actively involved in energy transduction
JANN_RS21245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JANN_RS21255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JANN_RS21265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JANN_RS21280	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JANN_RS21290	COG4786	Flagellar basal body rod
JANN_RS21295	COG4786	Flagellar basal body rod
JANN_RS21300	COG1987	bacterial-type flagellum assembly
JANN_RS21305	COG1677	Flagellar hook-basal body complex protein FliE
JANN_RS21310	COG1558	bacterial-type flagellum-dependent cell motility
JANN_RS21330	COG5443	negative regulation of bacterial-type flagellum assembly
JANN_RS21365	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JANN_RS21375	COG2226	methyltransferase
JANN_RS21380	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JANN_RS21385	COG1024	Enoyl-CoA hydratase
JANN_RS21390	COG0268	Binds directly to 16S ribosomal RNA
JANN_RS21730	COG1132	(ABC) transporter
JANN_RS21865	COG3591	Belongs to the peptidase S1B family
JANN_RS21890	COG3932	Exopolysaccharide synthesis, ExoD
JANN_RS21940	COG0631	protein serine/threonine phosphatase activity
JANN_RS21950	COG0515	serine threonine protein kinase
JANN_RS21950	COG2815	serine threonine protein kinase
JANN_RS21990	COG4191	Histidine kinase
JANN_RS21990	COG0784	Response regulator, receiver
JANN_RS22075	COG1129	ABC transporter
JANN_RS22120	COG3047	cAMP biosynthetic process
JANN_RS22120	COG2885	chlorophyll binding
JANN_RS22140	COG2201	protein-glutamate methylesterase activity
JANN_RS22200	COG4566	intracellular signal transduction
JANN_RS22305	COG3473	Maleate cis-trans isomerase