locus-tag	class	description
G7057_RS00080	ENOG4107QYV	phosphohexose isomerase
G7057_RS00095	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
G7057_RS00105	ENOG4105CAY	ferredoxin--nadp reductase
G7057_RS00110	ENOG4108W5N	phosphatidylglycerophosphatase a
G7057_RS00120	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
G7057_RS00125	ENOG4105MMD	transcriptional regulator
G7057_RS00130	ENOG4107R8B	5'-nucleotidase
G7057_RS00135	ENOG41090MY	MarR family Transcriptional regulator
G7057_RS00160	ENOG4105CN5	Metallo-Beta-Lactamase
G7057_RS00165	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
G7057_RS00170	ENOG4107Z33	ABC transporter, permease
G7057_RS00175	ENOG4108IJ9	(ABC) transporter
G7057_RS00225	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7057_RS00235	ENOG4105C1J	atp-dependent rna helicase
G7057_RS00250	ENOG4105DSG	hydrolase family 43
G7057_RS00255	ENOG4105BZU	Histidine kinase
G7057_RS00260	ENOG4105CPC	Aldo Keto reductase
G7057_RS00280	ENOG4105DQ4	alcohol dehydrogenase
G7057_RS00290	ENOG410756H	nucleotidyltransferase
G7057_RS00295	ENOG4105DIW	FeS assembly protein SUFB
G7057_RS00300	ENOG4108UNV	SUF system FeS assembly protein, NifU family
G7057_RS00310	ENOG4105JRK	feS assembly protein SufD
G7057_RS00325	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G7057_RS00345	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G7057_RS00360	ENOG41082BV	acetyltransferase
G7057_RS00370	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G7057_RS00375	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
G7057_RS00385	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G7057_RS00395	ENOG4105XZU	Preprotein translocase, subunit SecG
G7057_RS00405	ENOG4108JQ1	Dehydrogenase
G7057_RS00410	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G7057_RS00415	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G7057_RS00420	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G7057_RS00425	ENOG4105CP7	Triose-phosphate isomerase
G7057_RS00445	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G7057_RS00450	ENOG4108HMX	isocitrate dehydrogenase (NADP)
G7057_RS00455	ENOG4105BZN	citrate synthase
G7057_RS00460	ENOG4108I0Z	Aconitate hydratase
G7057_RS00490	ENOG4105DFF	Rod shape-determining protein mreb
G7057_RS00495	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G7057_RS00500	ENOG4106778	Protein of unknown function (DUF1146)
G7057_RS00505	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G7057_RS00525	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G7057_RS00530	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
G7057_RS00540	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
G7057_RS00550	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G7057_RS00555	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G7057_RS00560	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G7057_RS00565	ENOG4107104	thymidine kinase
G7057_RS00570	ENOG4105DMS	mur ligase
G7057_RS00575	ENOG4105F1K	Glutamine amidotransferase
G7057_RS00590	ENOG4105BZ1	(ABC) transporter
G7057_RS00595	ENOG4105BZ1	(ABC) transporter
G7057_RS00615	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
G7057_RS00620	ENOG4105CI1	PTS System
G7057_RS00645	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G7057_RS00650	ENOG4105E2X	shikimate dehydrogenase
G7057_RS00660	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
G7057_RS00670	ENOG4105CFH	Aspartokinase
G7057_RS00695	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
G7057_RS00700	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
G7057_RS00720	ENOG4105KG3	cytidine deaminase
G7057_RS00725	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
G7057_RS00740	ENOG4105RNB	
G7057_RS00745	ENOG4108Z3G	3H domain protein
G7057_RS00805	ENOG4105EPR	degv family
G7057_RS00810	ENOG410906U	SprT-like
G7057_RS00815	ENOG4107R7Y	intracellular protease Pfpi family
G7057_RS00820	ENOG4105H67	Protein of unknown function (DUF421)
G7057_RS00830	ENOG4107S1Q	Phosphatase
G7057_RS00835	ENOG4105C7N	Xanthine uracil vitamin C permease
G7057_RS00845	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7057_RS00850	ENOG4105DC8	reductase
G7057_RS00860	ENOG4105FGV	Chromate
G7057_RS00875	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
G7057_RS00880	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G7057_RS00895	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
G7057_RS00900	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
G7057_RS00915	ENOG4105CZV	ABC transporter
G7057_RS00920	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
G7057_RS00925	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G7057_RS00935	ENOG4108JEM	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7057_RS00940	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G7057_RS00945	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G7057_RS00950	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
G7057_RS00980	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7057_RS01030	ENOG4105C7K	acetolactate synthase
G7057_RS01085	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G7057_RS01090	ENOG4108Z6Z	Transcriptional regulator
G7057_RS01095	ENOG4105ZUU	Transcriptional regulator
G7057_RS01100	ENOG4105MU5	relaxase mobilization nuclease domain protein
G7057_RS01120	ENOG4105DZR	Type I site-specific deoxyribonuclease
G7057_RS01145	ENOG4105EKQ	RNA-directed DNA polymerase
G7057_RS01180	ENOG4105ZX1	Transposase C
G7057_RS01185	ENOG4108KU9	integrase family
G7057_RS01190	ENOG4108FPN	Integrase
G7057_RS01195	ENOG4105W5Q	DNA repair protein (RadC
G7057_RS01205	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7057_RS01220	ENOG4105K4H	Nlp p60 protein
G7057_RS01260	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
G7057_RS01265	ENOG4107QJE	Chromosome Partitioning Protein
G7057_RS01410	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7057_RS01415	ENOG4105CS9	pantothenic acid kinase
G7057_RS01435	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
G7057_RS01450	ENOG4105KT7	mgtC SapB transporter
G7057_RS01455	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
G7057_RS01460	ENOG4105E66	phosphoriboisomerase A
G7057_RS01470	ENOG4105EJQ	L-serine dehydratase
G7057_RS01475	ENOG4107RUE	extracellular solute-binding protein family 1
G7057_RS01480	ENOG4105D38	putrescine abc transporter
G7057_RS01485	ENOG4105F38	ABC transporter, permease
G7057_RS01490	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G7057_RS01500	ENOG4108JJB	ABC transporter
G7057_RS01505	ENOG4105D4A	Cell wall formation (By similarity)
G7057_RS01515	ENOG4108MK9	spermidine N(1)-acetyltransferase
G7057_RS01520	ENOG4105K8N	protein family UPF0079, ATPase
G7057_RS01525	ENOG4108IJ2	phosphate acetyltransferase
G7057_RS01535	ENOG4105DEN	Luciferase family
G7057_RS01550	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G7057_RS01555	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G7057_RS01570	ENOG4105CDA	abc transporter atp-binding protein
G7057_RS01590	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G7057_RS01595	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
G7057_RS01605	ENOG4105C5H	ABC transporter
G7057_RS01615	ENOG4105CHR	reductase
G7057_RS01625	ENOG4105EYH	Exonuclease
G7057_RS01630	ENOG4107YZX	Universal stress protein
G7057_RS01650	ENOG4105PNM	synthesis protein
G7057_RS01665	ENOG4107ZYJ	bioY protein
G7057_RS01670	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G7057_RS01700	ENOG4108HCJ	Hydrolase
G7057_RS01705	ENOG4105CFC	Transporter
G7057_RS01710	ENOG4105ZMH	deoxynucleoside kinase
G7057_RS01720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G7057_RS01725	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G7057_RS01730	ENOG4108JQ6	ABC transporter
G7057_RS01735	ENOG4108QEG	Membrane
G7057_RS01745	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G7057_RS01750	ENOG4105D98	threonine synthase
G7057_RS01770	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
G7057_RS01795	ENOG4108UIC	UPF0340 protein
G7057_RS01805	ENOG4105CDA	abc transporter atp-binding protein
G7057_RS01810	ENOG4105E5Q	amino acid AbC transporter
G7057_RS01815	ENOG4105DPN	Oligoendopeptidase f
G7057_RS01820	ENOG4107S3C	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
G7057_RS01840	ENOG4105EEM	helicase
G7057_RS01845	ENOG4105CVG	Homoserine O-transsuccinylase
G7057_RS01855	ENOG4105CHU	acetyl-coa acetyltransferase
G7057_RS01860	ENOG4105EMU	Dehydrogenase
G7057_RS01865	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
G7057_RS01910	ENOG4105CMG	Carbohydrate kinase
G7057_RS01915	ENOG4108YYH	Nadph-dependent fmn reductase
G7057_RS01920	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G7057_RS01930	ENOG4105CGH	5'-nucleotidase
G7057_RS01935	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7057_RS01940	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7057_RS01955	ENOG4105K8R	UPF0145 protein
G7057_RS01965	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
G7057_RS01975	ENOG4108REF	Sporulation integral membrane protein ytvi
G7057_RS01985	ENOG410901P	UPF0249 protein
G7057_RS01995	ENOG4108UQV	Membrane
G7057_RS02000	ENOG4108D32	Methyltransferase
G7057_RS02010	ENOG4107ZXU	DSBA oxidoreductase
G7057_RS02020	ENOG4108TZY	GntR Family Transcriptional Regulator
G7057_RS02025	ENOG4105CK1	PTS System
G7057_RS02035	ENOG4105EN6	Membrane
G7057_RS02045	ENOG4105VPX	protein, conserved in bacteria
G7057_RS02055	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
G7057_RS02070	ENOG4105WH5	Teichoic acid glycosylation protein
G7057_RS02080	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G7057_RS02090	ENOG4105C8Y	Acetylornithine aminotransferase
G7057_RS02095	ENOG4105CAS	nag kinase
G7057_RS02105	ENOG4105CDH	Citrulline--aspartate ligase
G7057_RS02150	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7057_RS02170	ENOG4105CH2	amidohydrolase
G7057_RS02175	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
G7057_RS02180	ENOG4105CDA	abc transporter atp-binding protein
G7057_RS02185	ENOG4108HW4	amino acid AbC transporter
G7057_RS02195	ENOG4105CHF	Glutathione S-transferase
G7057_RS02200	ENOG4105CHF	Glutathione S-transferase
G7057_RS02205	ENOG4105CHF	Glutathione S-transferase
G7057_RS02215	ENOG4105E3A	(ABC) transporter
G7057_RS02220	ENOG4105DA5	(ABC) transporter
G7057_RS02230	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G7057_RS02235	ENOG4108R6K	riboflavin synthase, subunit alpha
G7057_RS02240	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G7057_RS02250	ENOG4105D01	(LipO)protein
G7057_RS02260	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
G7057_RS02265	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
G7057_RS02305	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7057_RS02315	ENOG4105F3R	pts system mannose fructose sorbose family iid
G7057_RS02320	ENOG4105ETZ	PTS System
G7057_RS02330	ENOG4105DAS	pts system
G7057_RS02335	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G7057_RS02345	ENOG4105CPC	Aldo Keto reductase
G7057_RS02350	ENOG4106HK8	GPR1 FUN34 yaaH family protein
G7057_RS02370	ENOG4106A3R	peptidase
G7057_RS02375	ENOG4106855	Competence protein
G7057_RS02385	ENOG4105CZX	twitching motility protein
G7057_RS02390	ENOG4107QHF	type ii secretion system protein e
G7057_RS02400	ENOG4105BZU	Histidine kinase
G7057_RS02410	ENOG4105BZ1	(ABC) transporter
G7057_RS02415	ENOG4105BZ1	(ABC) transporter
G7057_RS02430	ENOG4108PGP	mmge prpd family protein
G7057_RS02435	ENOG4105EAB	amino acid AbC transporter
G7057_RS02445	ENOG4108HW4	amino acid AbC transporter
G7057_RS02460	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
G7057_RS02465	ENOG4105C6T	cysteine synthase
G7057_RS02475	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7057_RS02495	ENOG4106TD9	Diguanylate cyclase
G7057_RS02500	ENOG4105BZU	Histidine kinase
G7057_RS02510	ENOG4105ETE	Transcriptional regulator (LacI family
G7057_RS02515	ENOG4105N5T	Radical SAM Protein
G7057_RS02520	ENOG4105ST3	Transcriptional regulator
G7057_RS02525	ENOG4105ECB	domain protein
G7057_RS02565	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G7057_RS02585	ENOG4105D9U	N-acetyltransferase
G7057_RS02590	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
G7057_RS02615	ENOG4105C5Y	PTS System
G7057_RS02620	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7057_RS02635	ENOG4108RYK	Nad-dependent epimerase dehydratase
G7057_RS02640	ENOG4108Z40	Transcriptional regulator
G7057_RS02645	ENOG4108MJ3	acetyltransferase
G7057_RS02700	ENOG4105C19	ABC transporter
G7057_RS02730	ENOG4105ZX1	Transposase C
G7057_RS02735	ENOG4108KU9	integrase family
G7057_RS02740	ENOG4108FPN	Integrase
G7057_RS02745	ENOG4105W5Q	DNA repair protein (RadC
G7057_RS02760	ENOG4106BHR	ftsk SpoIIIE family protein
G7057_RS02785	ENOG4108UJD	30S ribosomal protein S9
G7057_RS02790	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G7057_RS02805	ENOG4108JJB	ABC transporter
G7057_RS02810	ENOG4108JJB	ABC transporter
G7057_RS02820	ENOG4108ZT0	50S ribosomal protein l17
G7057_RS02825	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7057_RS02830	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G7057_RS02835	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7057_RS02840	ENOG41067V7	50S ribosomal protein L36
G7057_RS02850	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G7057_RS02855	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G7057_RS02860	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G7057_RS02865	ENOG4105VPB	50S ribosomal protein L30
G7057_RS02870	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G7057_RS02875	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G7057_RS02880	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G7057_RS02885	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G7057_RS02890	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G7057_RS02895	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7057_RS02900	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G7057_RS02905	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G7057_RS02910	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G7057_RS02915	ENOG41082SA	50s ribosomal protein l29
G7057_RS02920	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G7057_RS02925	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G7057_RS02935	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G7057_RS02940	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7057_RS02945	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G7057_RS02950	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G7057_RS02955	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G7057_RS02960	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G7057_RS02965	ENOG4105D6A	Electron transport complex
G7057_RS02970	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
G7057_RS02980	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G7057_RS02985	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G7057_RS02990	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G7057_RS02995	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G7057_RS03005	ENOG4105CRK	lysyL-tRNA synthetase
G7057_RS03010	ENOG4105C6T	cysteine synthase
G7057_RS03015	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G7057_RS03020	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G7057_RS03025	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G7057_RS03030	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G7057_RS03035	ENOG41060GV	RNA binding s1 domain protein
G7057_RS03045	ENOG41082I2	s4 domain protein
G7057_RS03050	ENOG4108IY2	MazG family
G7057_RS03060	ENOG4108JA2	transcriptioN-repair coupling factor
G7057_RS03065	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G7057_RS03070	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G7057_RS03075	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G7057_RS03085	ENOG4105DFT	pur operon repressor
G7057_RS03095	ENOG4105FDK	ABC transporter
G7057_RS03100	ENOG4105DSE	periplasmic solute binding protein
G7057_RS03105	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G7057_RS03110	ENOG4105W42	Veg protein
G7057_RS03115	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G7057_RS03125	ENOG4105F8V	Hydrolase, tatD family
G7057_RS03130	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G7057_RS03160	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
G7057_RS03170	ENOG4105D9R	oxidoreductase
G7057_RS03175	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
G7057_RS03185	ENOG4105D17	glycoside hydrolase, family 3 domain protein
G7057_RS03195	ENOG4105DMW	Dehydrogenase reductase
G7057_RS03200	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
G7057_RS03205	ENOG4105D2H	Uronic isomerase
G7057_RS03210	ENOG4108UHU	Aldolase
G7057_RS03220	ENOG4105BZ1	(ABC) transporter
G7057_RS03225	ENOG4105BZ1	(ABC) transporter
G7057_RS03235	ENOG4108Z66	YbaK ebsC protein
G7057_RS03245	ENOG4108IUX	(ABC) transporter
G7057_RS03250	ENOG4105RHA	ABC transporter, permease
G7057_RS03255	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G7057_RS03260	ENOG4105CHM	Aminotransferase
G7057_RS03265	ENOG4108ZB6	transcriptional regulator AsnC family
G7057_RS03270	ENOG4105D17	glycoside hydrolase, family 3 domain protein
G7057_RS03280	ENOG4105CT4	transporter
G7057_RS03290	ENOG4106ZEE	Diacylglycerol kinase
G7057_RS03300	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
G7057_RS03360	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G7057_RS03370	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G7057_RS03380	ENOG4107258	Transcriptional regulator
G7057_RS03390	ENOG4105BZ1	(ABC) transporter
G7057_RS03395	ENOG4105BZ1	(ABC) transporter
G7057_RS03420	ENOG4105J4Q	Transcriptional regulator
G7057_RS03430	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
G7057_RS03435	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G7057_RS03450	ENOG4105HUF	DNA protection during starvation protein
G7057_RS03470	ENOG4108ZJ4	polysaccharide deacetylase
G7057_RS03480	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
G7057_RS03490	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G7057_RS03495	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
G7057_RS03500	ENOG4108WBT	adenosyltransferase
G7057_RS03520	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7057_RS03525	ENOG4105EPR	degv family
G7057_RS03530	ENOG4105CG3	alpha amylase, catalytic region
G7057_RS03565	ENOG4105C87	Aminotransferase class I and II
G7057_RS03620	ENOG4105C7Z	Conserved Protein
G7057_RS03630	ENOG41087YS	Phage shock protein A
G7057_RS03635	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
G7057_RS03640	ENOG4105CID	antiterminator
G7057_RS03645	ENOG4105CH2	amidohydrolase
G7057_RS03655	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G7057_RS03660	ENOG4108W15	Protein of unknown function (DUF1456)
G7057_RS03665	ENOG4108YBP	pseudouridine synthase
G7057_RS03675	ENOG4105CMQ	Chloride channel
G7057_RS03735	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G7057_RS03755	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
G7057_RS03760	ENOG4105DVE	abc transporter atp-binding protein
G7057_RS03770	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
G7057_RS03795	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G7057_RS03800	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G7057_RS03810	ENOG4105E2R	ROK family
G7057_RS03815	ENOG4108UW5	maltose o-acetyltransferase
G7057_RS03825	ENOG4107414	GntR family transcriptional regulator
G7057_RS03830	ENOG4105C9Q	fumarate hydratase class II
G7057_RS03835	ENOG4105C6K	Malic enzyme
G7057_RS03850	ENOG4108YBP	pseudouridine synthase
G7057_RS03865	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
G7057_RS03890	ENOG4107TXC	Transcriptional regulator
G7057_RS03895	ENOG4105CFP	Peptidase U32
G7057_RS03905	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G7057_RS03910	ENOG4105RKW	reductase (By
G7057_RS03920	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
G7057_RS03940	ENOG4105CEV	competence damage-inducible protein
G7057_RS03945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7057_RS03970	ENOG4105ETE	Transcriptional regulator (LacI family
G7057_RS03980	ENOG4107R3K	hydrolase
G7057_RS03990	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
G7057_RS04000	ENOG4105VEQ	Cold shock protein
G7057_RS04045	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
G7057_RS04055	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G7057_RS04070	ENOG4105EVU	fructokinase
G7057_RS04085	ENOG4105CG3	alpha amylase, catalytic region
G7057_RS04090	ENOG4105C5Y	PTS System
G7057_RS04095	ENOG4108HKT	sucrose-6-phosphate hydrolase
G7057_RS04100	ENOG4105ETE	Transcriptional regulator (LacI family
G7057_RS04125	ENOG4105C0H	protease
G7057_RS04130	ENOG4105Q2H	domain protein
G7057_RS04145	ENOG4105BZU	Histidine kinase
G7057_RS04150	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7057_RS04165	ENOG4105C37	(CBS) domain
G7057_RS04175	ENOG4105C5X	domain protein
G7057_RS04180	ENOG410807C	QueT transporter
G7057_RS04190	ENOG4108BUD	transposase
G7057_RS04255	ENOG4105EWM	Histidine kinase
G7057_RS04265	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G7057_RS04270	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G7057_RS04280	ENOG4105C1J	atp-dependent rna helicase
G7057_RS04285	ENOG4105DRP	amino acid AbC transporter
G7057_RS04295	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
G7057_RS04300	ENOG4105CPF	Cell wall formation (By similarity)
G7057_RS04320	ENOG41082DI	50s ribosomal protein l31
G7057_RS04330	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G7057_RS04335	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G7057_RS04350	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G7057_RS04355	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
G7057_RS04365	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
G7057_RS04370	ENOG4105DCI	Phosphohydrolase
G7057_RS04395	ENOG4105CS2	ec 3.2.1.21
G7057_RS04400	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G7057_RS04405	ENOG4105C83	adenylosuccinate lyase
G7057_RS04420	ENOG4105X71	Membrane
G7057_RS04425	ENOG4105CHM	Aminotransferase
G7057_RS04435	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G7057_RS04440	ENOG4108UMI	ABC transporter, permease
G7057_RS04445	ENOG4105D01	(LipO)protein
G7057_RS04450	ENOG4105D01	(LipO)protein
G7057_RS04505	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7057_RS04510	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
G7057_RS04520	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
G7057_RS04525	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
G7057_RS04530	ENOG4108DBC	nitroreductase
G7057_RS04535	ENOG4108Z5K	methylglyoxal synthase
G7057_RS04550	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G7057_RS04555	ENOG4105C1A	potassium transporter peripheral membrane
G7057_RS04590	ENOG4105CS2	ec 3.2.1.21
G7057_RS04595	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G7057_RS04600	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G7057_RS04605	ENOG4107VFR	oxidoreductase
G7057_RS04610	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G7057_RS04630	ENOG4105VC4	domain protein
G7057_RS04635	ENOG41060K3	Methyltransferase
G7057_RS04640	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
G7057_RS04645	ENOG4105MA4	psp1 domain protein
G7057_RS04650	ENOG4105FA2	dna polymerase iii
G7057_RS04655	ENOG4105X0R	protein from nitrogen regulatory protein P-II
G7057_RS04660	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G7057_RS04670	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G7057_RS04675	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G7057_RS04680	ENOG4105C6E	dna polymerase iii
G7057_RS04700	ENOG4108Z6B	deaminase
G7057_RS04710	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G7057_RS04715	ENOG4108TZY	GntR Family Transcriptional Regulator
G7057_RS04740	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7057_RS04745	ENOG4105KEX	transcriptional regulator, ctsr
G7057_RS04810	ENOG4105D6J	arsenicaL-resistance protein
G7057_RS04815	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
G7057_RS04845	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G7057_RS04855	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7057_RS04860	ENOG4105HUF	DNA protection during starvation protein
G7057_RS04865	ENOG4105UQX	Mate efflux family protein
G7057_RS04885	ENOG4106A3R	peptidase
G7057_RS04890	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7057_RS04895	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7057_RS04900	ENOG4107Y49	methyltransferase
G7057_RS04905	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G7057_RS04910	ENOG4108VZM	50s ribosomal protein L10
G7057_RS04915	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G7057_RS04920	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G7057_RS04925	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G7057_RS04935	ENOG4107FTN	50S ribosomal protein L33
G7057_RS04950	ENOG41088B0	Major membrane immunogen
G7057_RS04955	ENOG4105EAH	synthase
G7057_RS04965	ENOG4105CEP	NADH dehydrogenase
G7057_RS04980	ENOG4105M0M	Tetracycline resistance protein
G7057_RS04985	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G7057_RS04990	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G7057_RS04995	ENOG4105C8N	cysteinyl-tRNA synthetase
G7057_RS05000	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G7057_RS05005	ENOG4105CTP	PilT protein domain protein
G7057_RS05010	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G7057_RS05015	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G7057_RS05020	ENOG4108IJ9	(ABC) transporter
G7057_RS05045	ENOG4107QSE	Dipeptidase
G7057_RS05060	ENOG4108MEK	Metal-binding protein YodA
G7057_RS05075	ENOG4107YB6	acetyltransferase, (GNAT) family
G7057_RS05085	ENOG4105C5F	glutamine synthetase
G7057_RS05090	ENOG4105KV4	Transcriptional regulator
G7057_RS05110	ENOG4107RBD	ABC, transporter
G7057_RS05115	ENOG4107RPQ	ABC transporter
G7057_RS05120	ENOG4105DIK	(ABC) transporter
G7057_RS05125	ENOG4105DSE	periplasmic solute binding protein
G7057_RS05135	ENOG4105CAG	UPF0210 protein
G7057_RS05155	ENOG4105C28	cystathionine
G7057_RS05160	ENOG4105C87	Aminotransferase class I and II
G7057_RS05315	ENOG4105DG6	mannose-6-phosphate isomerase
G7057_RS05320	ENOG4105EVU	fructokinase
G7057_RS05330	ENOG4105CDU	Replicative dna helicase
G7057_RS05335	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G7057_RS05345	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G7057_RS05350	ENOG4108UUM	single-stranded DNA-binding protein
G7057_RS05355	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G7057_RS05360	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7057_RS05365	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7057_RS05370	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G7057_RS05375	ENOG410848D	S4 domain protein YaaA
G7057_RS05380	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G7057_RS05385	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G7057_RS05390	ENOG4105VG0	50S ribosomal protein l34
G7057_RS05395	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G7057_RS05400	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G7057_RS05410	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G7057_RS05430	ENOG4105C8Q	Methyl-accepting chemotaxis
G7057_RS05435	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
G7057_RS05440	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G7057_RS05445	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G7057_RS05450	ENOG4105BZU	Histidine kinase
G7057_RS05455	ENOG4105CBS	Chea signal transduction histidine kinase
G7057_RS05465	ENOG4107YTP	response regulator receiver protein
G7057_RS05470	ENOG4108V3W	Chemotaxis protein, CheW
G7057_RS05475	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G7057_RS05480	ENOG4105DD5	Flagellar motor switch protein
G7057_RS05495	ENOG4105E1Q	flagellar hook-associated protein
G7057_RS05505	ENOG4105I03	Flagellin
G7057_RS05515	ENOG4105DTS	flagellar hook-associated
G7057_RS05525	ENOG4105MQ3	flagellar protein FliS
G7057_RS05530	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
G7057_RS05535	ENOG4108ZC9	flagellar basal-body rod protein flgc
G7057_RS05540	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
G7057_RS05545	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
G7057_RS05550	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G7057_RS05585	ENOG4108JQA	flagellar
G7057_RS05595	ENOG4107R0U	MotA TolQ exbB proton channel
G7057_RS05600	ENOG4106VK6	Flagellar motor protein
G7057_RS05615	ENOG4105CN7	Flagellar biosynthetic protein FliP
G7057_RS05620	ENOG4105VS8	Flagellar biosynthetic protein fliq
G7057_RS05625	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
G7057_RS05630	ENOG4105D00	flagellar biosynthetic protein flhB
G7057_RS05635	ENOG4105D7B	Flagellar biosynthesis protein flha
G7057_RS05640	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7057_RS05645	ENOG4105CGA	flagellar basal-body rod protein FlgG
G7057_RS05650	ENOG4105CGA	flagellar basal-body rod protein FlgG
G7057_RS05655	ENOG4105CAK	Cell division ATP-binding protein ftsE
G7057_RS05675	ENOG4105CG3	alpha amylase, catalytic region
G7057_RS05695	ENOG4105HMI	Membrane
G7057_RS05700	ENOG4105DND	Transcriptional regulator
G7057_RS05705	ENOG4105CGK	Exodeoxyribonuclease III
G7057_RS05720	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G7057_RS05730	ENOG4105DQ6	Transposase
G7057_RS05755	ENOG4107414	GntR family transcriptional regulator
G7057_RS05760	ENOG4105D1Q	UPF0246 protein
G7057_RS05765	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G7057_RS05770	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
G7057_RS05805	ENOG4108YYH	Nadph-dependent fmn reductase
G7057_RS05825	ENOG4105CJ1	ABC, transporter
G7057_RS05845	ENOG4105BZ1	(ABC) transporter
G7057_RS05865	ENOG4105CT4	transporter
G7057_RS05875	ENOG41067QW	Transcriptional regulator
G7057_RS05895	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G7057_RS05900	ENOG4107QJE	Chromosome Partitioning Protein
G7057_RS05905	ENOG4105FA0	parb-like partition protein
G7057_RS05910	ENOG4105VDK	protein, conserved in bacteria
G7057_RS05915	ENOG4105C3G	gtp-binding protein
G7057_RS05925	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G7057_RS05945	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G7057_RS06005	ENOG4107QM2	Aldo Keto reductase
G7057_RS06035	ENOG410830R	acetyltransferase
G7057_RS06040	ENOG4105R1C	Catalyzes the acylation of glycosyl-4,4'- diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12- methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains (By similarity)
G7057_RS06050	ENOG4105FE1	phytoene synthase
G7057_RS06055	ENOG4108V06	Glutathione peroxidase
G7057_RS06065	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
G7057_RS06070	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
G7057_RS06075	ENOG4105CD3	dihydroorotase
G7057_RS06090	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
G7057_RS06095	ENOG4105C59	p-type ATPase
G7057_RS06135	ENOG4105KWG	Pfam:DUF1696
G7057_RS06140	ENOG4105C8B	TIGR00159 family
G7057_RS06150	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G7057_RS06185	ENOG4108MXZ	Esterase
G7057_RS06195	ENOG4105FE1	phytoene synthase
G7057_RS06210	ENOG4105K56	Transcriptional regulator
G7057_RS06220	ENOG4105BZ1	(ABC) transporter
G7057_RS06225	ENOG4105BZ1	(ABC) transporter
G7057_RS06240	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
G7057_RS06245	ENOG4108ZMX	Domain of unknown function (DU1801)
G7057_RS06250	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G7057_RS06285	ENOG4105C59	p-type ATPase
G7057_RS06300	ENOG4105W5Q	DNA repair protein (RadC
G7057_RS06370	ENOG4108IYH	Dna topoisomerase
G7057_RS06395	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G7057_RS06400	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
G7057_RS06405	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G7057_RS06430	ENOG4105C5H	ABC transporter
G7057_RS06445	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
G7057_RS06505	ENOG4106QJ6	Integrase catalytic subunit
G7057_RS06520	ENOG4105VZ8	Transcriptional regulator
G7057_RS06545	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G7057_RS06555	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G7057_RS06575	ENOG4105DJ4	phosphatidylserine decarboxylase
G7057_RS06595	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G7057_RS06600	ENOG4107XC4	flavin reductase domain protein, FMN-binding
G7057_RS06605	ENOG4107TDE	lipolytic protein G-D-S-L family
G7057_RS06615	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
G7057_RS06625	ENOG4105MU9	integral membrane protein
G7057_RS06635	ENOG4105F5H	Glycosyl Hydrolase Family 88
G7057_RS06645	ENOG41075H3	AraC family transcriptional regulator
G7057_RS06655	ENOG4105NTD	Inherit from COG: Hydrolase
G7057_RS06665	ENOG4105DSG	hydrolase family 43
G7057_RS06675	ENOG4105D2H	Uronic isomerase
G7057_RS06680	ENOG4105C2F	Histidine kinase
G7057_RS06685	ENOG4105EQD	regulatoR
G7057_RS06690	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
G7057_RS06705	ENOG4105F5H	Glycosyl Hydrolase Family 88
G7057_RS06720	ENOG4108Z6X	(sortase) family
G7057_RS06755	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G7057_RS06760	ENOG4105C5Y	PTS System
G7057_RS06785	ENOG4105CT4	transporter
G7057_RS06790	ENOG4105CT4	transporter
G7057_RS06795	ENOG4108K2B	transcriptional regulator
G7057_RS06800	ENOG4105I3N	Conserved Protein
G7057_RS06805	ENOG41069HH	4-oxalocrotonate tautomerase
G7057_RS06810	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
G7057_RS06815	ENOG4105EP9	oxidoreductase
G7057_RS06830	ENOG4105CPC	Aldo Keto reductase
G7057_RS06835	ENOG4105EPR	degv family
G7057_RS06855	ENOG4107YZX	Universal stress protein
G7057_RS06870	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G7057_RS06875	ENOG4108S4H	thioesterase Superfamily protein
G7057_RS06880	ENOG4105VPS	UPF0291 protein
G7057_RS06885	ENOG4105FBA	Phospholipase Carboxylesterase
G7057_RS06895	ENOG4105C93	Xylose Isomerase
G7057_RS06900	ENOG4105CMG	Carbohydrate kinase
G7057_RS06915	ENOG41072GX	Peptidase M22 Glycoprotease
G7057_RS06920	ENOG410801F	ribosomal-protein-alanine acetyltransferase
G7057_RS06925	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
G7057_RS06930	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G7057_RS06935	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
G7057_RS06940	ENOG4105C5H	ABC transporter
G7057_RS06945	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
G7057_RS06960	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G7057_RS06965	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G7057_RS06970	ENOG4108JNI	Alpha beta hydrolase
G7057_RS06975	ENOG4105E98	transcriptional regulator DeoR family
G7057_RS06980	ENOG4105DE4	1-phosphofructokinase
G7057_RS06985	ENOG4105DM4	PTS System
G7057_RS06990	ENOG4107T9C	Alpha amylase catalytic region
G7057_RS07000	ENOG4105DAP	Nicotinate phosphoribosyltransferase
G7057_RS07005	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
G7057_RS07015	ENOG4105ESV	Glycosyl transferase, family 4
G7057_RS07020	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
G7057_RS07025	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G7057_RS07035	ENOG4105M7V	2'-5' rna ligase
G7057_RS07055	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G7057_RS07060	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
G7057_RS07065	ENOG4105CAK	Cell division ATP-binding protein ftsE
G7057_RS07070	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
G7057_RS07075	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G7057_RS07080	ENOG4105BZU	Histidine kinase
G7057_RS07085	ENOG4107S17	Phosphate-binding protein
G7057_RS07090	ENOG4105C8U	phosphate abc transporter
G7057_RS07095	ENOG4105E2Z	phosphate ABC transporter (Permease
G7057_RS07100	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G7057_RS07105	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G7057_RS07110	ENOG4105KTU	Transcriptional regulator, arsr family
G7057_RS07115	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G7057_RS07120	ENOG4108PY7	
G7057_RS07125	ENOG41067S9	phage shock protein C, PspC
G7057_RS07130	ENOG41086DT	Membrane protein of unknown function
G7057_RS07135	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
G7057_RS07140	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G7057_RS07145	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G7057_RS07150	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G7057_RS07155	ENOG4105C3M	thioredoxin reductase
G7057_RS07160	ENOG4105E5Q	amino acid AbC transporter
G7057_RS07165	ENOG4106PMH	Extracellular solute-binding protein family 3
G7057_RS07185	ENOG4105E90	ABC transporter
G7057_RS07195	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G7057_RS07200	ENOG4105CHW	UPF0052 protein
G7057_RS07205	ENOG4105CIE	May be required for sporulation (By similarity)
G7057_RS07210	ENOG4105Z8H	single-stranded DNA-binding protein
G7057_RS07215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7057_RS07220	ENOG4105BZU	Histidine kinase
G7057_RS07235	ENOG4105DR4	Methyltransferase
G7057_RS07240	ENOG4105CBX	hi0933 family
G7057_RS07250	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7057_RS07260	ENOG4105CP9	extracellular ligand-binding receptor
G7057_RS07265	ENOG4105C32	Amino acid ABC transporter (Permease)
G7057_RS07270	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G7057_RS07275	ENOG4105C0Z	ABC transporter
G7057_RS07280	ENOG4108IV0	ABC, transporter
G7057_RS07285	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G7057_RS07305	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
G7057_RS07310	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G7057_RS07315	ENOG4105C4R	Atp-dependent dna helicase
G7057_RS07320	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G7057_RS07330	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G7057_RS07335	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G7057_RS07340	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G7057_RS07350	ENOG4107URF	beta-phospho-glucomutase
G7057_RS07360	ENOG4105CI1	PTS System
G7057_RS07370	ENOG4105CBD	Diacylglycerol kinase
G7057_RS07390	ENOG41067XF	inhibitor
G7057_RS07400	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
G7057_RS07405	ENOG4105C75	arginyL-tRNA synthetase
G7057_RS07410	ENOG4105K4I	Scp-like extracellular
G7057_RS07425	ENOG4105VEM	Conserved domain protein
G7057_RS07445	ENOG4105EPR	degv family
G7057_RS07450	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G7057_RS07455	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7057_RS07465	ENOG4105CHR	reductase
G7057_RS07470	ENOG4105D01	(LipO)protein
G7057_RS07480	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G7057_RS07490	ENOG4105D85	methylase
G7057_RS07495	ENOG4105F6A	helicase
G7057_RS07500	ENOG4105ECI	YeeC-like protein
G7057_RS07550	ENOG4105C2M	dna polymerase I
G7057_RS07590	ENOG4105DQ6	Transposase
G7057_RS07625	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G7057_RS07630	ENOG4105EAM	Na Pi-cotransporter
G7057_RS07655	ENOG4105CGK	Exodeoxyribonuclease III
G7057_RS07665	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
G7057_RS07670	ENOG4105C8Q	Methyl-accepting chemotaxis
G7057_RS07680	ENOG4105C5H	ABC transporter
G7057_RS07695	ENOG4105DDQ	anthranilate synthase
G7057_RS07710	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G7057_RS07715	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G7057_RS07720	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G7057_RS07725	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
G7057_RS07730	ENOG4105KGF	protein, YerC YecD
G7057_RS07740	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G7057_RS07745	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G7057_RS07755	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G7057_RS07760	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G7057_RS07765	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G7057_RS07780	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
G7057_RS07830	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G7057_RS07840	ENOG4105WD1	Membrane
G7057_RS07845	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G7057_RS07850	ENOG4105E5Q	amino acid AbC transporter
G7057_RS07855	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
G7057_RS07870	ENOG4105CK5	oxidoreductase
G7057_RS07875	ENOG4105FDU	atp-dependent rna helicase
G7057_RS07880	ENOG4105CQ4	Transcriptional regulator
G7057_RS07890	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
G7057_RS07895	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
G7057_RS07900	ENOG4105E70	isomerase
G7057_RS07905	ENOG4105CE4	GlcNAc 6-P deacetylase
G7057_RS07925	ENOG4105C88	aminopeptidase
G7057_RS07935	ENOG4105NQC	Flavodoxin
G7057_RS07960	ENOG4105DCF	alanine dehydrogenase
G7057_RS07965	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
G7057_RS07970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7057_RS07980	ENOG4106N3A	copper homeostasis protein cutc
G7057_RS07990	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
G7057_RS07995	ENOG4107RSM	transcriptional regulator
G7057_RS08005	ENOG4105C1J	atp-dependent rna helicase
G7057_RS08020	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
G7057_RS08025	ENOG4105C5Y	PTS System
G7057_RS08030	ENOG4108HKT	sucrose-6-phosphate hydrolase
G7057_RS08040	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
G7057_RS08090	ENOG4105D17	glycoside hydrolase, family 3 domain protein
G7057_RS08130	ENOG4105F5H	Glycosyl Hydrolase Family 88
G7057_RS08155	ENOG4105D3Q	Sugar transferase
G7057_RS08175	ENOG4105C5E	polysaccharide biosynthesis protein
G7057_RS08185	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G7057_RS08195	ENOG4107STW	synthase
G7057_RS08225	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7057_RS08230	ENOG4105CHU	acetyl-coa acetyltransferase
G7057_RS08240	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
G7057_RS08250	ENOG4105F9F	transposase
G7057_RS08255	ENOG4105HTX	biosynthesis protein
G7057_RS08260	ENOG4107YJ4	chain length determinant protein
G7057_RS08265	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
G7057_RS08285	ENOG4106QJ6	Integrase catalytic subunit
G7057_RS08300	ENOG4106QJ6	Integrase catalytic subunit
G7057_RS08320	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
G7057_RS08325	ENOG4108KGH	TRANSCRIPTIONal
G7057_RS08330	ENOG4108KGH	TRANSCRIPTIONal
G7057_RS08335	ENOG4105CMR	udp-glucose 4-epimerase
G7057_RS08345	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G7057_RS08360	ENOG4105C5E	polysaccharide biosynthesis protein
G7057_RS08370	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G7057_RS08380	ENOG4108KMV	Glycosyl transferase (Group 1
G7057_RS08400	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G7057_RS08405	ENOG4107X35	defense response to bacterium
G7057_RS08415	ENOG4105CKK	Glycosyl transferase, family 2
G7057_RS08420	ENOG4105EXC	Acyl-transferase
G7057_RS08430	ENOG4106QJ6	Integrase catalytic subunit
G7057_RS08440	ENOG4108IUK	alpha amylase, catalytic
G7057_RS08460	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
G7057_RS08490	ENOG410902V	Modulates RecA activity (By similarity)
G7057_RS08495	ENOG4105CEN	a g-specific adenine glycosylase
G7057_RS08500	ENOG4105EVI	UPF0374 protein
G7057_RS08510	ENOG4108IUM	Glycogen debranching enzyme
G7057_RS08515	ENOG410667J	hydrolase
G7057_RS08520	ENOG4107NBY	Membrane
G7057_RS08525	ENOG4105G5W	regulator Fur family
G7057_RS08530	ENOG4105FKQ	transcriptional regulator
G7057_RS08535	ENOG4105II7	pyrroline-5-carboxylate reductase
G7057_RS08540	ENOG4105CG3	alpha amylase, catalytic region
G7057_RS08545	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
G7057_RS08550	ENOG4107FKK	extracellular solute-binding protein family 1
G7057_RS08560	ENOG4105EG2	ABC transporter, permease
G7057_RS08575	ENOG4107URF	beta-phospho-glucomutase
G7057_RS08650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7057_RS08675	ENOG4105DHI	Methyltransferase
G7057_RS08680	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G7057_RS08685	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G7057_RS08690	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G7057_RS08700	ENOG4105C37	(CBS) domain
G7057_RS08705	ENOG4105BZ4	penicillin-binding protein
G7057_RS08710	ENOG4105WZB	UPF0342 protein
G7057_RS08715	ENOG4107VRP	DNA repair exonuclease
G7057_RS08720	ENOG4106D4I	domain protein
G7057_RS08730	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G7057_RS08740	ENOG4105K59	histidine triad (HIT) protein
G7057_RS08755	ENOG4108V15	phosphotransferase enzyme family
G7057_RS08780	ENOG4108VDD	TRNA binding domain protein
G7057_RS08790	ENOG4105DFU	Cell wall formation (By similarity)
G7057_RS08800	ENOG4105C2M	dna polymerase I
G7057_RS08805	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G7057_RS08810	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G7057_RS08815	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G7057_RS08830	ENOG4105C22	threonyL-tRNA synthetase
G7057_RS08840	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G7057_RS08845	ENOG4105VJV	50s ribosomal protein L35
G7057_RS08850	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G7057_RS08865	ENOG4105K56	Transcriptional regulator
G7057_RS08870	ENOG4105CIS	alcohol dehydrogenase
G7057_RS08875	ENOG4108TVJ	Nitroreductase
G7057_RS08885	ENOG4105KA3	membrAne
G7057_RS08895	ENOG4108C33	Resolvase
G7057_RS08900	ENOG4107QMH	DNA methylase
G7057_RS08915	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G7057_RS08925	ENOG4105C1Q	protoporphyrinogen oxidase
G7057_RS08930	ENOG4108RQ5	Beta-lactamase domain-containing protein
G7057_RS08935	ENOG4105DF9	Lipoate-protein, ligase
G7057_RS08940	ENOG4105C31	Tryptophanyl-tRNA synthetase
G7057_RS08945	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
G7057_RS08950	ENOG4107ZGM	malolactic fermentation system
G7057_RS08955	ENOG4105VAW	lrga family
G7057_RS08960	ENOG41067MG	lrgb family
G7057_RS08970	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
G7057_RS08985	ENOG4105DPN	Oligoendopeptidase f
G7057_RS08990	ENOG4105T58	Dithiol-disulfide isomerase
G7057_RS08995	ENOG4105MIX	Adenylate cyclase
G7057_RS09005	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G7057_RS09015	ENOG4105EMS	pseudouridine synthase
G7057_RS09020	ENOG4105CJW	magnesium transporter
G7057_RS09025	ENOG4108HPG	-acetyltransferase
G7057_RS09030	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
G7057_RS09035	ENOG4105C37	(CBS) domain
G7057_RS09040	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G7057_RS09050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7057_RS09055	ENOG4105KRI	phosphocarrier protein (HPr
G7057_RS09060	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G7057_RS09065	ENOG4105BZF	Glycosyl transferase (Group 1
G7057_RS09070	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G7057_RS09075	ENOG4107IN1	Protein of unknown function (DUF1797)
G7057_RS09080	ENOG4105D6E	homoserine dehydrogenase
G7057_RS09085	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
G7057_RS09090	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
G7057_RS09095	ENOG4105CQW	ribosome biogenesis GTPase YqeH
G7057_RS09100	ENOG410812S	Rna-binding protein
G7057_RS09105	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
G7057_RS09110	ENOG4108WF2	Metal Dependent Phosphohydrolase
G7057_RS09120	ENOG4105DXX	methyltransferase
G7057_RS09125	ENOG4105CDE	UPF0348 protein
G7057_RS09135	ENOG41067VY	50S ribosomal protein L32
G7057_RS09150	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G7057_RS09155	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G7057_RS09160	ENOG4108V6E	Cell division protein mraZ
G7057_RS09165	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G7057_RS09175	ENOG4105CJN	penicillin-binding protein
G7057_RS09180	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G7057_RS09185	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G7057_RS09190	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G7057_RS09200	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G7057_RS09210	ENOG4105DFA	alanine racemase domain protein
G7057_RS09215	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
G7057_RS09225	ENOG4105DBK	s4 domain protein
G7057_RS09235	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G7057_RS09240	ENOG4105VEQ	Cold shock protein
G7057_RS09245	ENOG4107BMA	Transglycosylase associated protein
G7057_RS09250	ENOG4105CDW	Resistance protein
G7057_RS09260	ENOG4108YZ4	nudix hydrolase
G7057_RS09285	ENOG4105CM4	permease protein
G7057_RS09290	ENOG4108IPW	abc transporter atp-binding protein
G7057_RS09300	ENOG4105VTR	Integrase
G7057_RS09350	ENOG4105JBR	DNA replication protein
G7057_RS09360	ENOG4108TFU	terminase (Small subunit)
G7057_RS09405	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G7057_RS09410	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
G7057_RS09415	ENOG4105C3J	Cysteine desulfurase
G7057_RS09420	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
G7057_RS09425	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
G7057_RS09430	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G7057_RS09435	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G7057_RS09440	ENOG4105W5Q	DNA repair protein (RadC
G7057_RS09450	ENOG4105VEQ	Cold shock protein
G7057_RS09455	ENOG4105DFF	Rod shape-determining protein mreb
G7057_RS09460	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G7057_RS09470	ENOG4105E89	ABC transporter
G7057_RS09475	ENOG4108HW3	(ABC) transporter
G7057_RS09495	ENOG4105E5Q	amino acid AbC transporter
G7057_RS09500	ENOG4105CDA	abc transporter atp-binding protein
G7057_RS09505	ENOG4107RGD	Major Facilitator superfamily
G7057_RS09510	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G7057_RS09515	ENOG4105X36	(ribosomal) protein
G7057_RS09530	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
G7057_RS09550	ENOG4105D1H	recombination factor protein RarA
G7057_RS09555	ENOG4105D9M	gamma-glutamylcysteine synthetase
G7057_RS09565	ENOG4105C3J	Cysteine desulfurase
G7057_RS09580	ENOG4105YPM	F pilin acetylation protein TraX
G7057_RS09585	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G7057_RS09590	ENOG4105C7H	Helicase, RecD TraA family
G7057_RS09600	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G7057_RS09605	ENOG4105VBH	UPF0297 protein
G7057_RS09610	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G7057_RS09615	ENOG4105VPH	UPF0473 protein
G7057_RS09620	ENOG4105HHA	aminodeoxychorismate lyase
G7057_RS09625	ENOG4105DBI	uridine monophosphokinase
G7057_RS09630	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G7057_RS09640	ENOG4105ENE	Histidine kinase
G7057_RS09645	ENOG4105WH1	Two component transcriptional regulator luxr family
G7057_RS09655	ENOG4105CN5	Metallo-Beta-Lactamase
G7057_RS09675	ENOG4107YB9	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G7057_RS09680	ENOG4107R37	Glutamate dehydrogenase
G7057_RS09685	ENOG4107RUY	(E1 component), alpha subunit
G7057_RS09695	ENOG4105C7S	Dehydrogenase
G7057_RS09705	ENOG4105WBI	UPF0223 protein
G7057_RS09710	ENOG4105ECY	inositol monophosphatase
G7057_RS09715	ENOG4105CI3	gtp-binding protein typa
G7057_RS09720	ENOG4105ZPI	UPF0358 protein
G7057_RS09725	ENOG4105CNI	cell division protein FtsW
G7057_RS09740	ENOG4105WUC	UPF0298 protein
G7057_RS09745	ENOG4106H78	methyltransferase
G7057_RS09750	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G7057_RS09755	ENOG4105KQC	Competence protein
G7057_RS09760	ENOG4108UK2	deaminase
G7057_RS09765	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
G7057_RS09770	ENOG4105TQK	DNA polymerase iii, delta' subunit
G7057_RS09775	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
G7057_RS09780	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G7057_RS09785	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G7057_RS09790	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G7057_RS09795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G7057_RS09845	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G7057_RS09855	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
G7057_RS09860	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G7057_RS09865	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G7057_RS09870	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G7057_RS09875	ENOG4105C25	Primosomal protein n'
G7057_RS09880	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G7057_RS09885	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G7057_RS09895	ENOG4105D9P	serine threonine protein kinase
G7057_RS09900	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G7057_RS09905	ENOG4105DJV	ribulose-phosphate 3-epimerase
G7057_RS09910	ENOG4105FJ0	thiamine
G7057_RS09920	ENOG4108ZAA	Alkaline-shock protein
G7057_RS09925	ENOG4105DP4	dak2 domain fusion protein ylov
G7057_RS09930	ENOG4105CB5	ATP-dependent DNA helicase recG
G7057_RS09935	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
G7057_RS09950	ENOG4108JQ7	(ABC) transporter
G7057_RS09955	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G7057_RS09960	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G7057_RS09970	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G7057_RS09975	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G7057_RS09980	ENOG410667J	hydrolase
G7057_RS09985	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G7057_RS09990	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
G7057_RS10000	ENOG4105K5M	30s ribosomal protein S16
G7057_RS10005	ENOG4105VB6	UPF0109 protein
G7057_RS10010	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G7057_RS10015	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G7057_RS10020	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G7057_RS10025	ENOG4105KVH	Transcriptional regulator
G7057_RS10045	ENOG4108KP7	hydrolase
G7057_RS10055	ENOG4105VG1	fes assembly suf system protein
G7057_RS10065	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7057_RS10070	ENOG4105F7J	membrane-bound serine protease
G7057_RS10075	ENOG4105DI5	UPF0365 protein
G7057_RS10095	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G7057_RS10100	ENOG4105VIE	preprotein translocase, subunit YajC
G7057_RS10110	ENOG4105C0A	alcohol dehydrogenase
G7057_RS10115	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7057_RS10125	ENOG4105E8R	UPF0173 metal-dependent hydrolase
G7057_RS10135	ENOG4105SFS	phosphoesterase RecJ domain protein
G7057_RS10140	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
G7057_RS10145	ENOG4105C1J	atp-dependent rna helicase
G7057_RS10155	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G7057_RS10165	ENOG4107RF6	penicillin-binding protein
G7057_RS10180	ENOG4105WDJ	50S ribosomal protein L33
G7057_RS10185	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G7057_RS10195	ENOG4105DKQ	ROK family
G7057_RS10210	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
G7057_RS10215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7057_RS10220	ENOG4105GR3	Histidine kinase
G7057_RS10225	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
G7057_RS10240	ENOG4105CNU	cell division protein FtsK
G7057_RS10245	ENOG4105DIH	basic membrane
G7057_RS10250	ENOG4108JQ9	ABC transporter
G7057_RS10255	ENOG4105UIB	(ABC) transporter
G7057_RS10275	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
G7057_RS10285	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G7057_RS10290	ENOG4105CEV	competence damage-inducible protein
G7057_RS10295	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G7057_RS10305	ENOG4105D48	metallophosphoesterase
G7057_RS10315	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G7057_RS10320	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G7057_RS10330	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G7057_RS10335	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G7057_RS10340	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G7057_RS10350	ENOG4105C0B	DNA polymerase III (alpha subunit)
G7057_RS10355	ENOG4105CTQ	phosphohexokinase
G7057_RS10365	ENOG4105QNR	S1 RNA binding domain protein
G7057_RS10370	ENOG4105I3K	Ferric uptake regulator, Fur family
G7057_RS10380	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
G7057_RS10385	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
G7057_RS10395	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G7057_RS10400	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G7057_RS10405	ENOG4105FE9	pseudouridine synthase
G7057_RS10410	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7057_RS10415	ENOG4105BZU	Histidine kinase
G7057_RS10420	ENOG4108SAX	Membrane
G7057_RS10435	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7057_RS10440	ENOG4107X35	defense response to bacterium
G7057_RS10445	ENOG4105CAT	Cytidine monophosphate kinase
G7057_RS10450	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G7057_RS10455	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G7057_RS10465	ENOG41068YB	TPR repeat-containing protein
G7057_RS10470	ENOG4108SXZ	UPF0302 protein
G7057_RS10475	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G7057_RS10485	ENOG4105DVT	helicase
G7057_RS10500	ENOG4105C5S	asparaginyl-tRNA synthetase
G7057_RS10515	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
G7057_RS10520	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G7057_RS10525	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G7057_RS10530	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G7057_RS10535	ENOG4105DEU	major facilitator superfamily
G7057_RS10540	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G7057_RS10545	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7057_RS10555	ENOG4105EGD	dinuclear metal center protein, YbgI family
G7057_RS10560	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
G7057_RS10570	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G7057_RS10575	ENOG4105DTN	riboflavin biosynthesis protein ribF
G7057_RS10580	ENOG4105CSA	Coproporphyrinogen iii oxidase
G7057_RS10585	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G7057_RS10590	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7057_RS10595	ENOG4105CFG	Acts as a chaperone (By similarity)
G7057_RS10600	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G7057_RS10605	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G7057_RS10615	ENOG4105DZ6	Band 7 protein
G7057_RS10620	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G7057_RS10625	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G7057_RS10630	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
G7057_RS10635	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
G7057_RS10640	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
G7057_RS10645	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G7057_RS10650	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G7057_RS10655	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G7057_RS10660	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G7057_RS10665	ENOG4105C12	Phosphoribosylglycinamide synthetase
G7057_RS10670	ENOG4105CKU	formyltetrahydrofolate synthetase
G7057_RS10675	ENOG4105C5H	ABC transporter
G7057_RS10680	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
G7057_RS10700	ENOG4108UT2	hemolysin iii
G7057_RS10715	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
G7057_RS10730	ENOG4105C3F	Signal peptidase i
G7057_RS10735	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
G7057_RS10740	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7057_RS10745	ENOG4105C79	DNA protecting protein DprA
G7057_RS10750	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G7057_RS10755	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G7057_RS10760	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G7057_RS10765	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
G7057_RS10770	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
G7057_RS10775	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
G7057_RS10780	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7057_RS10795	ENOG4105F1A	Pyruvate formate-lyase
G7057_RS10800	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
G7057_RS10815	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
G7057_RS10830	ENOG4108HW4	amino acid AbC transporter
G7057_RS10835	ENOG4105CDA	abc transporter atp-binding protein
G7057_RS10840	ENOG4108UZ3	Transporter
G7057_RS10845	ENOG4105VG1	fes assembly suf system protein
G7057_RS10850	ENOG4105C01	Dihydroxy-acid dehydratase
G7057_RS10855	ENOG4105C7K	acetolactate synthase
G7057_RS10860	ENOG4108ZP8	Acetolactate synthase small subunit
G7057_RS10865	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G7057_RS10870	ENOG4105DKW	ABC transporter
G7057_RS10875	ENOG4105C7B	Threonine dehydratase
G7057_RS10880	ENOG4105KME	endoribonuclease L-psp
G7057_RS10885	ENOG4105CSM	endonuclease III
G7057_RS10900	ENOG4105DER	m42 family
G7057_RS10905	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
G7057_RS10910	ENOG4108IGT	Dipeptidase
G7057_RS10955	ENOG4105CJ1	ABC, transporter
G7057_RS10960	ENOG4105WH1	Two component transcriptional regulator luxr family
G7057_RS10965	ENOG4105BZU	Histidine kinase
G7057_RS10970	ENOG4108YYH	Nadph-dependent fmn reductase
G7057_RS11010	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G7057_RS11030	ENOG4105C7J	ABC transporter, permease
G7057_RS11060	ENOG4105C34	Pseudouridine synthase
G7057_RS11065	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G7057_RS11085	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
G7057_RS11090	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
G7057_RS11095	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G7057_RS11110	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
G7057_RS11115	ENOG4105CHV	Transcription elongation factor NusA
G7057_RS11120	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G7057_RS11125	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
G7057_RS11130	ENOG4105DZP	Membrane-associated zinc metalloprotease
G7057_RS11135	ENOG4105KNE	Phosphatidate cytidylyltransferase
G7057_RS11140	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G7057_RS11145	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G7057_RS11150	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G7057_RS11155	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G7057_RS11160	ENOG4105CE9	30S ribosomal protein S2
G7057_RS11165	ENOG4105F6E	Acyl-transferase
G7057_RS11170	ENOG4105BZ1	(ABC) transporter
G7057_RS11175	ENOG4105BZ1	(ABC) transporter
G7057_RS11180	ENOG4105VXM	UPF0154 protein
G7057_RS11185	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G7057_RS11190	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G7057_RS11195	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G7057_RS11205	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
G7057_RS11210	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7057_RS11215	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G7057_RS11220	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
G7057_RS11225	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
G7057_RS11230	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G7057_RS11235	ENOG4107YR5	Diacylglycerol kinase
G7057_RS11240	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G7057_RS11245	ENOG4105C9A	Phoh family
G7057_RS11255	ENOG4105N80	Ferric uptake regulator, Fur family
G7057_RS11260	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
G7057_RS11265	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
G7057_RS11270	ENOG4105C9M	aspartyl-trna synthetase
G7057_RS11275	ENOG4105CUT	histidyl-tRNA synthetase
G7057_RS11280	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G7057_RS11285	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G7057_RS11290	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G7057_RS11295	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
G7057_RS11300	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G7057_RS11305	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G7057_RS11320	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
G7057_RS11330	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G7057_RS11335	ENOG4105VND	Ribonuclease
G7057_RS11350	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
G7057_RS11355	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G7057_RS11360	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G7057_RS11365	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G7057_RS11375	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G7057_RS11380	ENOG4105CHR	reductase
G7057_RS11385	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G7057_RS11390	ENOG4105EA8	2-Nitropropane dioxygenase
G7057_RS11395	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G7057_RS11420	ENOG4105CXI	aluminum resistance protein
G7057_RS11425	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G7057_RS11430	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G7057_RS11435	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
G7057_RS11440	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G7057_RS11445	ENOG4105DX0	Hemolysin A
G7057_RS11460	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G7057_RS11465	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G7057_RS11470	ENOG4105M7K	Involved in the transcription termination process (By similarity)
G7057_RS11475	ENOG4108ZSR	alkaline shock protein
G7057_RS11480	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G7057_RS11485	ENOG4105DC7	peptidase M24
G7057_RS11525	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
G7057_RS11530	ENOG4105CDY	transcriptional regulatory protein
G7057_RS11540	ENOG4106ZEE	Diacylglycerol kinase
G7057_RS11545	ENOG4105C72	UPF0176 protein
G7057_RS11555	ENOG4105ETE	Transcriptional regulator (LacI family
G7057_RS11575	ENOG4105D8X	mechanosensitive ion channel
G7057_RS11590	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G7057_RS11605	ENOG4105K63	Thioredoxin
G7057_RS11610	ENOG4105C98	muts2 protein
G7057_RS11620	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
G7057_RS11635	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G7057_RS11640	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G7057_RS11655	ENOG4108RWN	rrna methyltransferase
G7057_RS11660	ENOG4105E4C	Lytic transglycosylase catalytic
G7057_RS11670	ENOG4107QSE	Dipeptidase
G7057_RS11690	ENOG4105C8T	Leucyl-tRNA synthetase
G7057_RS11695	ENOG4107X35	defense response to bacterium
G7057_RS11715	ENOG4105T16	Transcriptional regulator (AraC family)
G7057_RS11720	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP