locus-tag	class	description
G7057_RS00080	COG0166	Belongs to the GPI family
G7057_RS00090	COG1098	S1 RNA binding domain
G7057_RS00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7057_RS00100	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
G7057_RS00105	COG0492	ferredoxin-NADP+ reductase activity
G7057_RS00110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G7057_RS00120	COG0647	UMP catabolic process
G7057_RS00125	COG4470	Protein conserved in bacteria
G7057_RS00130	COG0737	Belongs to the 5'-nucleotidase family
G7057_RS00135	COG1846	Transcriptional regulator
G7057_RS00160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G7057_RS00165	COG0395	ABC-type sugar transport system, permease component
G7057_RS00170	COG1175	transmembrane transport
G7057_RS00175	COG3842	ATPase activity
G7057_RS00225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7057_RS00250	COG3507	Belongs to the glycosyl hydrolase 43 family
G7057_RS00255	COG2199	diguanylate cyclase activity
G7057_RS00255	COG2200	EAL domain
G7057_RS00255	COG3287	FIST C domain
G7057_RS00260	COG0667	Aldo Keto reductase
G7057_RS00280	COG1064	alcohol dehydrogenase
G7057_RS00290	COG3541	Predicted nucleotidyltransferase
G7057_RS00295	COG0719	Fe-S assembly protein
G7057_RS00300	COG0822	iron-sulfur transferase activity
G7057_RS00305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7057_RS00310	COG0719	Fe-S assembly protein
G7057_RS00320	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G7057_RS00325	COG0509	glycine decarboxylation via glycine cleavage system
G7057_RS00335	COG0772	Belongs to the SEDS family
G7057_RS00345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7057_RS00360	COG2153	protein acetylation
G7057_RS00370	COG0588	phosphoglycerate mutase activity
G7057_RS00375	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
G7057_RS00380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G7057_RS00385	COG0557	exoribonuclease II activity
G7057_RS00395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7057_RS00405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7057_RS00410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G7057_RS00415	COG0148	phosphopyruvate hydratase activity
G7057_RS00420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G7057_RS00425	COG0149	triose-phosphate isomerase activity
G7057_RS00440	COG2390	Transcriptional regulator
G7057_RS00445	COG0740	serine-type endopeptidase activity
G7057_RS00450	COG0538	isocitrate dehydrogenase activity
G7057_RS00455	COG0372	Belongs to the citrate synthase family
G7057_RS00460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G7057_RS00490	COG1077	Cell shape determining protein MreB Mrl
G7057_RS00495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G7057_RS00500	COG4836	Membrane
G7057_RS00505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7057_RS00515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G7057_RS00520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G7057_RS00525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7057_RS00530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7057_RS00535	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7057_RS00540	COG0356	it plays a direct role in the translocation of protons across the membrane
G7057_RS00550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7057_RS00555	COG2890	protein-(glutamine-N5) methyltransferase activity
G7057_RS00560	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7057_RS00565	COG1435	thymidine kinase activity
G7057_RS00570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7057_RS00575	COG3442	glutamine amidotransferase
G7057_RS00590	COG1132	(ABC) transporter
G7057_RS00595	COG1132	(ABC) transporter
G7057_RS00605	COG0628	permease
G7057_RS00615	COG2706	6-phosphogluconolactonase activity
G7057_RS00620	COG2190	(PTS) system
G7057_RS00620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS00620	COG1263	PTS System
G7057_RS00645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G7057_RS00650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G7057_RS00660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G7057_RS00670	COG0527	aspartate kinase activity
G7057_RS00680	COG0058	SHG alpha-glucan phosphorylase activity
G7057_RS00695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G7057_RS00720	COG0295	cytidine deaminase activity
G7057_RS00725	COG0371	Dehydrogenase
G7057_RS00745	COG1827	regulation of RNA biosynthetic process
G7057_RS00805	COG1307	EDD domain protein, DegV family
G7057_RS00810	COG3091	SprT-like family
G7057_RS00815	COG0693	protein deglycase activity
G7057_RS00820	COG2323	membrane
G7057_RS00825	COG2183	response to ionizing radiation
G7057_RS00830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7057_RS00835	COG2252	PERMEase
G7057_RS00845	COG0519	Catalyzes the synthesis of GMP from XMP
G7057_RS00850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7057_RS00860	COG2059	Chromate
G7057_RS00875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7057_RS00880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G7057_RS00895	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7057_RS00900	COG0346	lactoylglutathione lyase activity
G7057_RS00915	COG1131	(ABC) transporter
G7057_RS00920	COG1725	Transcriptional regulator
G7057_RS00925	COG0352	thiamine-phosphate diphosphorylase activity
G7057_RS00935	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7057_RS00940	COG0509	glycine decarboxylation via glycine cleavage system
G7057_RS00945	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G7057_RS00950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G7057_RS00955	COG0824	Thioesterase
G7057_RS00980	COG0514	ATP-dependent DNA helicase (RecQ)
G7057_RS01020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G7057_RS01030	COG0028	Belongs to the TPP enzyme family
G7057_RS01085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7057_RS01090	COG0789	Transcriptional regulator
G7057_RS01095	COG1396	sequence-specific DNA binding
G7057_RS01100	COG3843	relaxase mobilization nuclease domain protein
G7057_RS01120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G7057_RS01195	COG2003	Belongs to the UPF0758 family
G7057_RS01205	COG0551	DNA topoisomerase type I activity
G7057_RS01205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7057_RS01220	COG0741	lytic transglycosylase activity
G7057_RS01220	COG0791	NLP P60 protein
G7057_RS01260	COG1475	DNA binding
G7057_RS01265	COG1192	Involved in chromosome partitioning
G7057_RS01300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7057_RS01410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7057_RS01410	COG0519	Catalyzes the synthesis of GMP from XMP
G7057_RS01420	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7057_RS01435	COG1304	FMN binding
G7057_RS01450	COG1285	pathogenesis
G7057_RS01455	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G7057_RS01460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G7057_RS01465	COG1760	l-serine dehydratase
G7057_RS01470	COG1760	l-serine dehydratase
G7057_RS01475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G7057_RS01480	COG1177	transmembrane transport
G7057_RS01485	COG1176	ABC-type spermidine putrescine transport system, permease component I
G7057_RS01490	COG3842	ATPase activity
G7057_RS01500	COG1122	ATPase activity
G7057_RS01505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7057_RS01515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7057_RS01520	COG0802	atpase or kinase
G7057_RS01525	COG0280	phosphate acetyltransferase
G7057_RS01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7057_RS01550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7057_RS01555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7057_RS01570	COG1126	abc transporter atp-binding protein
G7057_RS01575	COG3584	3D domain protein
G7057_RS01590	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7057_RS01595	COG1114	Component of the transport system for branched-chain amino acids
G7057_RS01605	COG0488	(ABC) transporter
G7057_RS01625	COG0419	ATPase involved in DNA repair
G7057_RS01630	COG0589	response to stress
G7057_RS01650	COG2843	Capsule synthesis protein
G7057_RS01665	COG1268	BioY protein
G7057_RS01670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G7057_RS01670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G7057_RS01690	COG3682	Transcriptional regulator
G7057_RS01700	COG0561	phosphatase activity
G7057_RS01705	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G7057_RS01710	COG1428	Deoxynucleoside kinase
G7057_RS01735	COG4129	membrane
G7057_RS01745	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G7057_RS01770	COG3425	synthase
G7057_RS01795	COG4475	Protein of unknown function (DUF436)
G7057_RS01805	COG1126	abc transporter atp-binding protein
G7057_RS01810	COG0765	amino acid transport
G7057_RS01820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G7057_RS01840	COG3973	AAA domain
G7057_RS01845	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G7057_RS01850	COG2873	o-acetylhomoserine
G7057_RS01855	COG0183	Belongs to the thiolase family
G7057_RS01860	COG4221	oxidoreductase activity
G7057_RS01865	COG0346	lactoylglutathione lyase activity
G7057_RS01890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7057_RS01910	COG1070	Carbohydrate kinase
G7057_RS01915	COG0431	NADPH-dependent FMN reductase
G7057_RS01920	COG1764	response to oxidative stress
G7057_RS01930	COG0737	Belongs to the 5'-nucleotidase family
G7057_RS01935	COG0577	efflux transmembrane transporter activity
G7057_RS01935	COG1136	(ABC) transporter
G7057_RS01940	COG0577	efflux transmembrane transporter activity
G7057_RS01940	COG1136	(ABC) transporter
G7057_RS01955	COG0393	Putative heavy-metal-binding
G7057_RS01965	COG0840	transmembrane signaling receptor activity
G7057_RS01975	COG0628	permease
G7057_RS01985	COG3394	polysaccharide catabolic process
G7057_RS01995	COG1811	Na channel or pump
G7057_RS02000	COG2226	methyltransferase
G7057_RS02010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G7057_RS02020	COG2188	Transcriptional regulator
G7057_RS02025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7057_RS02030	COG1473	amidohydrolase
G7057_RS02035	COG2860	membrane
G7057_RS02045	COG1937	Protein conserved in bacteria
G7057_RS02055	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7057_RS02070	COG2246	polysaccharide biosynthetic process
G7057_RS02080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7057_RS02090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7057_RS02095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7057_RS02105	COG0137	argininosuccinate synthase activity
G7057_RS02150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7057_RS02170	COG1473	amidohydrolase
G7057_RS02175	COG0456	acetyltransferase
G7057_RS02185	COG0765	amino acid transport
G7057_RS02190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7057_RS02195	COG0435	Glutathione S-transferase
G7057_RS02200	COG0435	Glutathione S-transferase
G7057_RS02205	COG0435	Glutathione S-transferase
G7057_RS02215	COG0842	Transport permease protein
G7057_RS02220	COG1131	(ABC) transporter
G7057_RS02230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7057_RS02230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7057_RS02245	COG1045	serine acetyltransferase
G7057_RS02255	COG1394	ATPase activity, coupled to movement of substances
G7057_RS02260	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
G7057_RS02265	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
G7057_RS02285	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7057_RS02290	COG1269	ATP hydrolysis coupled proton transport
G7057_RS02300	COG0628	permease
G7057_RS02305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G7057_RS02315	COG3716	PTS system mannose fructose sorbose family IID component
G7057_RS02320	COG3715	PTS system
G7057_RS02330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS02330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7057_RS02335	COG3933	PFAM sigma-54 factor interaction domain-containing protein
G7057_RS02335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G7057_RS02340	COG0656	L-ascorbic acid biosynthetic process
G7057_RS02345	COG0667	Aldo Keto reductase
G7057_RS02350	COG1584	GPR1 FUN34 yaaH family protein
G7057_RS02370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7057_RS02375	COG4537	Required for transformation and DNA binding
G7057_RS02390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7057_RS02400	COG3706	GGDEF domain
G7057_RS02410	COG1132	(ABC) transporter
G7057_RS02415	COG1132	(ABC) transporter
G7057_RS02425	COG0583	DNA-binding transcription factor activity
G7057_RS02430	COG2079	MmgE PrpD family protein
G7057_RS02440	COG1126	abc transporter atp-binding protein
G7057_RS02445	COG0765	amino acid transport
G7057_RS02450	COG1473	amidohydrolase
G7057_RS02455	COG0456	acetyltransferase
G7057_RS02465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G7057_RS02475	COG0328	RNA-DNA hybrid ribonuclease activity
G7057_RS02495	COG3706	GGDEF domain
G7057_RS02500	COG3706	GGDEF domain
G7057_RS02510	COG1609	Transcriptional regulator
G7057_RS02515	COG1242	4 iron, 4 sulfur cluster binding
G7057_RS02520	COG1309	transcriptional regulator
G7057_RS02525	COG1511	domain protein
G7057_RS02565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7057_RS02580	COG0456	acetyltransferase
G7057_RS02585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7057_RS02590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G7057_RS02600	COG0546	phosphoglycolate phosphatase activity
G7057_RS02615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS02615	COG2190	(PTS) system
G7057_RS02615	COG1263	PTS System
G7057_RS02620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7057_RS02635	COG2910	NAD(P)H-binding
G7057_RS02640	COG1959	2 iron, 2 sulfur cluster binding
G7057_RS02700	COG1136	(ABC) transporter
G7057_RS02745	COG2003	Belongs to the UPF0758 family
G7057_RS02760	COG1674	ftsk spoiiie
G7057_RS02790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7057_RS02805	COG1122	ATPase activity
G7057_RS02810	COG1122	ATPase activity
G7057_RS02815	COG0346	lactoylglutathione lyase activity
G7057_RS02820	COG0203	ribosomal protein L17
G7057_RS02830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G7057_RS02835	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7057_RS02840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7057_RS02850	COG0563	adenylate kinase activity
G7057_RS02860	COG0200	Binds to the 23S rRNA
G7057_RS02865	COG1841	ribosomal large subunit assembly
G7057_RS02870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7057_RS02875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7057_RS02880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G7057_RS02885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7057_RS02895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7057_RS02900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7057_RS02905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7057_RS02910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7057_RS02920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7057_RS02925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7057_RS02930	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7057_RS02935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7057_RS02940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7057_RS02945	COG0089	rRNA binding
G7057_RS02950	COG0088	Forms part of the polypeptide exit tunnel
G7057_RS02955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7057_RS02965	COG4658	electron transport chain
G7057_RS02970	COG4656	Part of a membrane complex involved in electron transport
G7057_RS02975	COG0668	transmembrane transport
G7057_RS02980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7057_RS02985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G7057_RS02990	COG0049	tRNA binding
G7057_RS02995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7057_RS03005	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G7057_RS03010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G7057_RS03015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G7057_RS03020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7057_RS03030	COG0037	tRNA processing
G7057_RS03035	COG1098	S1 RNA binding domain
G7057_RS03045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G7057_RS03050	COG3956	TIGRFAM MazG family protein
G7057_RS03055	COG2244	polysaccharide biosynthetic process
G7057_RS03060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G7057_RS03065	COG0193	aminoacyl-tRNA hydrolase activity
G7057_RS03070	COG0039	L-malate dehydrogenase activity
G7057_RS03075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7057_RS03085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7057_RS03090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G7057_RS03095	COG1121	(ABC) transporter
G7057_RS03100	COG0803	Belongs to the bacterial solute-binding protein 9 family
G7057_RS03105	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G7057_RS03110	COG4466	Protein conserved in bacteria
G7057_RS03115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G7057_RS03120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G7057_RS03125	COG0084	hydrolase, TatD family'
G7057_RS03130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7057_RS03130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7057_RS03160	COG2249	NAD(P)H dehydrogenase (quinone) activity
G7057_RS03165	COG3250	beta-galactosidase activity
G7057_RS03170	COG0673	inositol 2-dehydrogenase activity
G7057_RS03175	COG0673	inositol 2-dehydrogenase activity
G7057_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
G7057_RS03200	COG1312	Catalyzes the dehydration of D-mannonate
G7057_RS03205	COG1904	glucuronate isomerase
G7057_RS03210	COG0800	Aldolase
G7057_RS03220	COG1132	(ABC) transporter
G7057_RS03225	COG1132	(ABC) transporter
G7057_RS03235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G7057_RS03245	COG4152	abc transporter atp-binding protein
G7057_RS03250	COG1668	transmembrane transport
G7057_RS03260	COG0436	Aminotransferase
G7057_RS03265	COG1522	sequence-specific DNA binding
G7057_RS03290	COG1597	lipid kinase activity
G7057_RS03300	COG4946	Tricorn protease homolog
G7057_RS03300	COG1506	peptidase
G7057_RS03300	COG0823	Involved in the tonB-independent uptake of proteins
G7057_RS03360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G7057_RS03370	COG0019	diaminopimelate decarboxylase activity
G7057_RS03380	COG1414	Transcriptional regulator
G7057_RS03390	COG1132	(ABC) transporter
G7057_RS03395	COG1132	(ABC) transporter
G7057_RS03420	COG1414	Transcriptional regulator
G7057_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
G7057_RS03430	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
G7057_RS03435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G7057_RS03450	COG0783	Belongs to the Dps family
G7057_RS03470	COG0726	polysaccharide deacetylase
G7057_RS03475	COG2738	Putative neutral zinc metallopeptidase
G7057_RS03480	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
G7057_RS03490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G7057_RS03490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G7057_RS03495	COG1028	Short-chain dehydrogenase reductase Sdr
G7057_RS03500	COG2096	Adenosyltransferase
G7057_RS03505	COG0628	permease
G7057_RS03510	COG1187	pseudouridine synthase activity
G7057_RS03525	COG1307	EDD domain protein, DegV family
G7057_RS03530	COG0366	Alpha amylase catalytic
G7057_RS03565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G7057_RS03615	COG0577	efflux transmembrane transporter activity
G7057_RS03615	COG1136	(ABC) transporter
G7057_RS03620	COG1331	Highly conserved protein containing a thioredoxin domain
G7057_RS03630	COG1842	Phage shock protein A
G7057_RS03635	COG2190	(PTS) system
G7057_RS03635	COG1263	PTS System
G7057_RS03635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS03640	COG3711	transcriptional antiterminator
G7057_RS03645	COG1473	amidohydrolase
G7057_RS03650	COG0166	Belongs to the GPI family
G7057_RS03655	COG2824	Alkylphosphonate utilization operon protein PhnA
G7057_RS03660	COG4807	Protein conserved in bacteria
G7057_RS03665	COG0564	pseudouridine synthase activity
G7057_RS03690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7057_RS03735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G7057_RS03755	COG1725	Transcriptional regulator
G7057_RS03760	COG1131	(ABC) transporter
G7057_RS03770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7057_RS03795	COG0473	3-isopropylmalate dehydrogenase activity
G7057_RS03800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7057_RS03810	COG1940	carbohydrate kinase activity
G7057_RS03815	COG0110	maltose O-acetyltransferase activity
G7057_RS03825	COG2188	Transcriptional regulator
G7057_RS03830	COG0114	fumarate hydratase activity
G7057_RS03835	COG0281	malic enzyme
G7057_RS03850	COG0564	pseudouridine synthase activity
G7057_RS03865	COG3976	FMN-binding domain protein
G7057_RS03865	COG0431	NADPH-dependent FMN reductase
G7057_RS03865	COG1053	succinate dehydrogenase
G7057_RS03890	COG0789	Transcriptional regulator
G7057_RS03905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7057_RS03910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G7057_RS03920	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
G7057_RS03925	COG1263	PTS System
G7057_RS03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS03925	COG2190	(PTS) system
G7057_RS03940	COG1546	Belongs to the CinA family
G7057_RS03940	COG1058	Belongs to the CinA family
G7057_RS03945	COG1136	(ABC) transporter
G7057_RS03965	COG0625	glutathione transferase activity
G7057_RS03970	COG1609	Transcriptional regulator
G7057_RS03980	COG1621	beta-fructofuranosidase activity
G7057_RS03990	COG0395	ABC-type sugar transport system, permease component
G7057_RS03995	COG4209	transmembrane transport
G7057_RS04000	COG1278	Cold shock
G7057_RS04045	COG3706	GGDEF domain
G7057_RS04055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G7057_RS04060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7057_RS04065	COG0569	domain protein
G7057_RS04070	COG1940	carbohydrate kinase activity
G7057_RS04085	COG0366	Alpha amylase catalytic
G7057_RS04100	COG1609	Transcriptional regulator
G7057_RS04125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7057_RS04130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G7057_RS04145	COG5002	protein histidine kinase activity
G7057_RS04150	COG0745	RESPONSE REGULATOR receiver
G7057_RS04165	COG1253	flavin adenine dinucleotide binding
G7057_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7057_RS04180	COG4708	membrane
G7057_RS04245	COG0577	efflux transmembrane transporter activity
G7057_RS04250	COG1136	(ABC) transporter
G7057_RS04255	COG5002	protein histidine kinase activity
G7057_RS04285	COG0765	amino acid transport
G7057_RS04295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7057_RS04300	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7057_RS04320	COG0254	rRNA binding
G7057_RS04330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G7057_RS04335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G7057_RS04350	COG0504	CTP synthase activity
G7057_RS04355	COG3343	RNA polymerase activity
G7057_RS04365	COG0095	Lipoate-protein ligase
G7057_RS04370	COG1078	dGTPase activity
G7057_RS04395	COG2723	6-phospho-beta-galactosidase activity
G7057_RS04400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7057_RS04405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G7057_RS04420	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G7057_RS04425	COG0436	Aminotransferase
G7057_RS04435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G7057_RS04440	COG2011	ABC-type metal ion transport system permease component
G7057_RS04445	COG1464	Belongs to the NlpA lipoprotein family
G7057_RS04450	COG1464	Belongs to the NlpA lipoprotein family
G7057_RS04485	COG1418	mRNA catabolic process
G7057_RS04505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7057_RS04510	COG1780	Probably involved in ribonucleotide reductase function
G7057_RS04530	COG0778	Nitroreductase
G7057_RS04535	COG1803	Methylglyoxal synthase
G7057_RS04550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7057_RS04555	COG0569	domain protein
G7057_RS04565	COG0656	L-ascorbic acid biosynthetic process
G7057_RS04570	COG0789	Transcriptional regulator
G7057_RS04590	COG2723	6-phospho-beta-galactosidase activity
G7057_RS04595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7057_RS04600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G7057_RS04605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7057_RS04610	COG1970	mechanosensitive ion channel activity
G7057_RS04630	COG2827	Endonuclease containing a URI domain
G7057_RS04635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G7057_RS04640	COG4467	Involved in initiation control of chromosome replication
G7057_RS04645	COG1774	PSP1 C-terminal conserved region
G7057_RS04650	COG0470	DNA polymerase III
G7057_RS04655	COG3870	Protein conserved in bacteria
G7057_RS04660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7057_RS04670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G7057_RS04675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7057_RS04680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G7057_RS04700	COG0590	tRNA wobble adenosine to inosine editing
G7057_RS04710	COG0009	L-threonylcarbamoyladenylate synthase
G7057_RS04715	COG2188	Transcriptional regulator
G7057_RS04735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G7057_RS04740	COG0542	response to heat
G7057_RS04745	COG4463	regulation of RNA biosynthetic process
G7057_RS04810	COG0798	PFAM Bile acid sodium symporter
G7057_RS04815	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7057_RS04820	COG0582	viral genome integration into host DNA
G7057_RS04840	COG2217	Heavy metal translocating P-type atpase
G7057_RS04845	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7057_RS04855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7057_RS04860	COG0783	Belongs to the Dps family
G7057_RS04865	COG0534	Mate efflux family protein
G7057_RS04885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7057_RS04890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7057_RS04900	COG2813	Specifically methylates the guanine in position
G7057_RS04905	COG0222	ribosome binding
G7057_RS04910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G7057_RS04915	COG0081	regulation of translation
G7057_RS04920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7057_RS04925	COG0250	Participates in transcription elongation, termination and antitermination
G7057_RS04930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7057_RS04935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7057_RS04950	COG4939	FMN-binding domain protein
G7057_RS04955	COG0142	geranyltranstransferase activity
G7057_RS04965	COG1252	NADH dehydrogenase
G7057_RS04980	COG3688	RNA-binding protein containing a PIN domain
G7057_RS04985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7057_RS04990	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G7057_RS04995	COG0215	cysteine-tRNA ligase activity
G7057_RS05000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7057_RS05005	COG4956	integral membrane protein (PIN domain superfamily)
G7057_RS05010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G7057_RS05015	COG0756	dUTP diphosphatase activity
G7057_RS05020	COG3842	ATPase activity
G7057_RS05030	COG0346	lactoylglutathione lyase activity
G7057_RS05045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7057_RS05060	COG3443	Belongs to the bacterial solute-binding protein 9 family
G7057_RS05075	COG2153	protein acetylation
G7057_RS05085	COG0174	glutamine synthetase
G7057_RS05090	COG0789	Transcriptional regulator
G7057_RS05110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G7057_RS05115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G7057_RS05120	COG1121	(ABC) transporter
G7057_RS05125	COG0803	Belongs to the bacterial solute-binding protein 9 family
G7057_RS05135	COG2848	UPF0210 protein
G7057_RS05140	COG3830	Belongs to the UPF0237 family
G7057_RS05155	COG0626	cystathionine gamma-synthase activity
G7057_RS05160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G7057_RS05315	COG1482	cell wall glycoprotein biosynthetic process
G7057_RS05320	COG1940	carbohydrate kinase activity
G7057_RS05330	COG0305	Participates in initiation and elongation during chromosome replication
G7057_RS05335	COG0359	binds to the 23S rRNA
G7057_RS05345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7057_RS05350	COG0629	single-stranded DNA binding
G7057_RS05355	COG0360	Binds together with S18 to 16S ribosomal RNA
G7057_RS05360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G7057_RS05365	COG0187	DNA topoisomerase II activity
G7057_RS05370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G7057_RS05375	COG2501	S4 domain
G7057_RS05380	COG0592	DNA-directed DNA polymerase activity
G7057_RS05385	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G7057_RS05390	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G7057_RS05400	COG0706	membrane insertase activity
G7057_RS05410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7057_RS05430	COG0840	transmembrane signaling receptor activity
G7057_RS05435	COG0835	chemotaxis
G7057_RS05440	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G7057_RS05445	COG2201	protein-glutamate methylesterase activity
G7057_RS05450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G7057_RS05455	COG0643	Histidine kinase
G7057_RS05455	COG2198	Histidine kinase
G7057_RS05460	COG1776	CheC inhibitor of MCP methylation
G7057_RS05465	COG2201	protein-glutamate methylesterase activity
G7057_RS05470	COG0835	chemotaxis
G7057_RS05475	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G7057_RS05480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G7057_RS05480	COG1776	CheC inhibitor of MCP methylation
G7057_RS05495	COG1256	bacterial-type flagellum assembly
G7057_RS05495	COG4786	Flagellar basal body rod
G7057_RS05505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G7057_RS05525	COG1516	flagellar protein fliS
G7057_RS05530	COG1815	bacterial-type flagellum-dependent cell motility
G7057_RS05535	COG1558	bacterial-type flagellum-dependent cell motility
G7057_RS05540	COG1677	Flagellar hook-basal body complex protein FliE
G7057_RS05545	COG1766	The M ring may be actively involved in energy transduction
G7057_RS05550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G7057_RS05560	COG1157	protein secretion by the type III secretion system
G7057_RS05585	COG4786	Flagellar basal body rod
G7057_RS05615	COG1338	Plays a role in the flagellum-specific transport system
G7057_RS05620	COG1987	bacterial-type flagellum assembly
G7057_RS05625	COG1684	flagellar biosynthetic protein fliR
G7057_RS05630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G7057_RS05635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G7057_RS05640	COG1191	sigma factor activity
G7057_RS05650	COG4786	Flagellar basal body rod
G7057_RS05655	COG2884	Cell division ATP-binding protein ftsE
G7057_RS05675	COG0366	Alpha amylase catalytic
G7057_RS05700	COG0583	DNA-binding transcription factor activity
G7057_RS05705	COG0708	Exodeoxyribonuclease III
G7057_RS05720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G7057_RS05730	COG2801	Transposase and inactivated derivatives
G7057_RS05750	COG0534	Mate efflux family protein
G7057_RS05755	COG2188	Transcriptional regulator
G7057_RS05760	COG3022	response to hydroperoxide
G7057_RS05765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G7057_RS05770	COG0445	tRNA wobble uridine modification
G7057_RS05780	COG0656	L-ascorbic acid biosynthetic process
G7057_RS05805	COG0431	NADPH-dependent FMN reductase
G7057_RS05825	COG1131	(ABC) transporter
G7057_RS05845	COG1132	(ABC) transporter
G7057_RS05865	COG2211	Major facilitator Superfamily
G7057_RS05875	COG3620	sequence-specific DNA binding
G7057_RS05895	COG0357	Ribosomal RNA small subunit methyltransferase G
G7057_RS05900	COG1192	Involved in chromosome partitioning
G7057_RS05905	COG1475	DNA binding
G7057_RS05910	COG4481	Protein conserved in bacteria
G7057_RS05915	COG0012	GTP binding
G7057_RS05925	COG0516	GMP reductase activity
G7057_RS05925	COG0517	IMP dehydrogenase activity
G7057_RS05940	COG1686	Belongs to the peptidase S11 family
G7057_RS05945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7057_RS06005	COG4989	oxidoreductase activity
G7057_RS06035	COG2388	GCN5-related N-acetyl-transferase
G7057_RS06055	COG0386	Belongs to the glutathione peroxidase family
G7057_RS06065	COG0167	dihydroorotate dehydrogenase activity
G7057_RS06070	COG0543	2 iron, 2 sulfur cluster binding
G7057_RS06075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G7057_RS06090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G7057_RS06095	COG2217	Heavy metal translocating P-type atpase
G7057_RS06140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G7057_RS06150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7057_RS06155	COG1609	Transcriptional regulator
G7057_RS06165	COG1874	Beta-galactosidase
G7057_RS06185	COG1073	alpha beta
G7057_RS06195	COG1562	ergosterol biosynthetic process
G7057_RS06210	COG1846	Transcriptional regulator
G7057_RS06220	COG1132	(ABC) transporter
G7057_RS06225	COG1132	(ABC) transporter
G7057_RS06240	COG0662	Cupin 2, conserved barrel domain protein
G7057_RS06245	COG5646	InterPro IPR014922
G7057_RS06250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G7057_RS06285	COG2217	Heavy metal translocating P-type atpase
G7057_RS06300	COG2003	Belongs to the UPF0758 family
G7057_RS06315	COG0582	viral genome integration into host DNA
G7057_RS06365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7057_RS06395	COG2226	methyltransferase
G7057_RS06405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7057_RS06430	COG0488	(ABC) transporter
G7057_RS06445	COG1192	Involved in chromosome partitioning
G7057_RS06520	COG1476	TRANSCRIPTIONal
G7057_RS06545	COG0456	acetyltransferase
G7057_RS06550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7057_RS06555	COG1968	undecaprenyl-diphosphatase activity
G7057_RS06575	COG0688	phosphatidylethanolamine metabolic process
G7057_RS06585	COG0574	Belongs to the PEP-utilizing enzyme family
G7057_RS06585	COG3848	Pyruvate phosphate dikinase
G7057_RS06595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7057_RS06600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G7057_RS06605	COG2755	lipolytic protein G-D-S-L family
G7057_RS06615	COG0395	ABC-type sugar transport system, permease component
G7057_RS06620	COG4209	transmembrane transport
G7057_RS06625	COG5578	integral membrane protein
G7057_RS06630	COG1653	transport
G7057_RS06635	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G7057_RS06645	COG2207	Transcriptional regulator
G7057_RS06655	COG1073	alpha beta
G7057_RS06665	COG3507	Belongs to the glycosyl hydrolase 43 family
G7057_RS06675	COG1904	glucuronate isomerase
G7057_RS06680	COG2972	Histidine kinase
G7057_RS06685	COG4753	response regulator
G7057_RS06685	COG2207	Transcriptional regulator
G7057_RS06690	COG1175	transmembrane transport
G7057_RS06695	COG0395	ABC-type sugar transport system, permease component
G7057_RS06705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G7057_RS06710	COG4894	glucomannan catabolic process
G7057_RS06715	COG1011	Hydrolase
G7057_RS06720	COG3764	Sortase (surface protein transpeptidase)
G7057_RS06755	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G7057_RS06760	COG1263	PTS System
G7057_RS06760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS06765	COG1737	Transcriptional regulator
G7057_RS06785	COG2211	Major facilitator Superfamily
G7057_RS06790	COG2211	Major facilitator Superfamily
G7057_RS06795	COG2169	Transcriptional regulator
G7057_RS06800	COG1801	Protein of unknown function DUF72
G7057_RS06805	COG1942	4-Oxalocrotonate Tautomerase
G7057_RS06830	COG0667	Aldo Keto reductase
G7057_RS06835	COG1307	EDD domain protein, DegV family
G7057_RS06855	COG0589	response to stress
G7057_RS06870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G7057_RS06875	COG1607	acyl-coa hydrolase
G7057_RS06885	COG0400	carboxylic ester hydrolase activity
G7057_RS06895	COG2115	Belongs to the xylose isomerase family
G7057_RS06900	COG1070	Carbohydrate kinase
G7057_RS06915	COG1214	PFAM Peptidase M22, glycoprotease
G7057_RS06920	COG0456	acetyltransferase
G7057_RS06925	COG0456	acetyltransferase
G7057_RS06930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G7057_RS06940	COG0488	(ABC) transporter
G7057_RS06960	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G7057_RS06965	COG0459	protein refolding
G7057_RS06970	COG2267	carboxylic ester hydrolase activity
G7057_RS06975	COG1349	DNA-binding transcription factor activity
G7057_RS06980	COG1105	Belongs to the carbohydrate kinase PfkB family
G7057_RS06985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7057_RS06985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7057_RS06985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7057_RS06990	COG0366	Alpha amylase catalytic
G7057_RS06995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G7057_RS07000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G7057_RS07015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7057_RS07020	COG1739	Uncharacterized protein family UPF0029
G7057_RS07025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7057_RS07030	COG1307	EDD domain protein, DegV family
G7057_RS07035	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G7057_RS07040	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G7057_RS07055	COG0653	protein targeting
G7057_RS07060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G7057_RS07065	COG2884	Cell division ATP-binding protein ftsE
G7057_RS07070	COG2177	Part of the ABC transporter FtsEX involved in
G7057_RS07075	COG0745	RESPONSE REGULATOR receiver
G7057_RS07080	COG5002	protein histidine kinase activity
G7057_RS07085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G7057_RS07090	COG0573	inorganic phosphate transmembrane transporter activity
G7057_RS07095	COG0581	inorganic phosphate transmembrane transporter activity
G7057_RS07100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7057_RS07105	COG0704	Plays a role in the regulation of phosphate uptake
G7057_RS07110	COG0640	Transcriptional regulator
G7057_RS07115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7057_RS07120	COG3595	metallopeptidase activity
G7057_RS07125	COG1983	PspC domain protein
G7057_RS07130	COG1950	PFAM Membrane protein of
G7057_RS07140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7057_RS07145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7057_RS07150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7057_RS07155	COG0492	ferredoxin-NADP+ reductase activity
G7057_RS07160	COG0765	amino acid transport
G7057_RS07170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7057_RS07185	COG1174	glycine betaine transport
G7057_RS07195	COG1660	Displays ATPase and GTPase activities
G7057_RS07200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G7057_RS07205	COG1481	regulation of sporulation
G7057_RS07210	COG0629	single-stranded DNA binding
G7057_RS07215	COG0745	RESPONSE REGULATOR receiver
G7057_RS07220	COG5002	protein histidine kinase activity
G7057_RS07220	COG3850	Histidine kinase
G7057_RS07230	COG1368	sulfuric ester hydrolase activity
G7057_RS07235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7057_RS07240	COG2081	HI0933 family
G7057_RS07250	COG1136	(ABC) transporter
G7057_RS07265	COG0559	Belongs to the binding-protein-dependent transport system permease family
G7057_RS07285	COG0516	GMP reductase activity
G7057_RS07285	COG0517	IMP dehydrogenase activity
G7057_RS07305	COG1705	Flagellar rod assembly protein muramidase FlgJ
G7057_RS07310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G7057_RS07315	COG0210	DNA helicase
G7057_RS07320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7057_RS07325	COG4851	CamS sex pheromone cAM373 precursor
G7057_RS07335	COG0154	amidase activity
G7057_RS07340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G7057_RS07345	COG1609	Transcriptional regulator
G7057_RS07350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7057_RS07360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7057_RS07360	COG2190	(PTS) system
G7057_RS07360	COG1263	PTS System
G7057_RS07370	COG1597	lipid kinase activity
G7057_RS07390	COG2732	(Barnase) inhibitor
G7057_RS07400	COG4876	unkown
G7057_RS07405	COG0018	arginyl-trna synthetase
G7057_RS07410	COG2340	Cysteine-rich secretory protein family
G7057_RS07425	COG4443	Transcriptional Coactivator p15 (PC4)
G7057_RS07445	COG1307	EDD domain protein, DegV family
G7057_RS07450	COG0322	excinuclease ABC activity
G7057_RS07455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7057_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
G7057_RS07480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7057_RS07490	COG1002	Type II restriction enzyme, methylase subunits
G7057_RS07495	COG1061	Type III restriction enzyme res subunit
G7057_RS07500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G7057_RS07550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7057_RS07550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7057_RS07590	COG2801	Transposase and inactivated derivatives
G7057_RS07610	COG1819	glycosyl
G7057_RS07625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7057_RS07645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7057_RS07655	COG0708	Exodeoxyribonuclease III
G7057_RS07660	COG4895	conserved protein (DUF2196)
G7057_RS07665	COG1854	S-ribosylhomocysteine lyase activity
G7057_RS07670	COG0840	transmembrane signaling receptor activity
G7057_RS07680	COG0488	(ABC) transporter
G7057_RS07695	COG0512	Glutamine amidotransferase of anthranilate synthase
G7057_RS07695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7057_RS07700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7057_RS07705	COG0134	indole-3-glycerol-phosphate synthase activity
G7057_RS07715	COG0133	tryptophan synthase activity
G7057_RS07720	COG0159	tryptophan synthase activity
G7057_RS07730	COG4496	protein, YerC YecD
G7057_RS07740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7057_RS07745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G7057_RS07755	COG0131	Imidazoleglycerol-phosphate dehydratase
G7057_RS07760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7057_RS07765	COG0107	imidazoleglycerol-phosphate synthase activity
G7057_RS07775	COG2213	PTS system mannitol-specific
G7057_RS07780	COG0363	glucosamine-6-phosphate deaminase activity
G7057_RS07830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7057_RS07840	COG2832	Protein of unknown function (DUF454)
G7057_RS07845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7057_RS07850	COG0765	amino acid transport
G7057_RS07855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7057_RS07865	COG0656	L-ascorbic acid biosynthetic process
G7057_RS07870	COG0673	inositol 2-dehydrogenase activity
G7057_RS07875	COG0513	Belongs to the DEAD box helicase family
G7057_RS07880	COG1609	Transcriptional regulator
G7057_RS07890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7057_RS07895	COG0516	GMP reductase activity
G7057_RS07900	COG2222	sugar isomerase
G7057_RS07910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7057_RS07925	COG2309	aminopeptidase activity
G7057_RS07935	COG0716	FMN binding
G7057_RS07940	COG0673	inositol 2-dehydrogenase activity
G7057_RS07960	COG0686	Belongs to the AlaDH PNT family
G7057_RS07965	COG0577	efflux transmembrane transporter activity
G7057_RS07970	COG1136	(ABC) transporter
G7057_RS07980	COG3142	Participates in the control of copper homeostasis
G7057_RS07990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G7057_RS07995	COG0583	DNA-binding transcription factor activity
G7057_RS08005	COG0513	Belongs to the DEAD box helicase family
G7057_RS08020	COG1472	Belongs to the glycosyl hydrolase 3 family
G7057_RS08040	COG0657	acetylesterase activity
G7057_RS08045	COG0024	Methionine aminopeptidase
G7057_RS08065	COG1136	(ABC) transporter
G7057_RS08070	COG0577	efflux transmembrane transporter activity
G7057_RS08075	COG0745	RESPONSE REGULATOR receiver
G7057_RS08080	COG2205	protein histidine kinase activity
G7057_RS08090	COG1472	Belongs to the glycosyl hydrolase 3 family
G7057_RS08130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G7057_RS08135	COG4975	Glucose uptake
G7057_RS08155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G7057_RS08165	COG1215	transferase activity, transferring glycosyl groups
G7057_RS08175	COG1086	Polysaccharide biosynthesis protein
G7057_RS08185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G7057_RS08195	COG0438	transferase activity, transferring glycosyl groups
G7057_RS08225	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7057_RS08230	COG0183	Belongs to the thiolase family
G7057_RS08240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G7057_RS08250	COG2826	transposase and inactivated derivatives, IS30 family
G7057_RS08255	COG3944	biosynthesis protein
G7057_RS08260	COG0489	protein tyrosine kinase activity
G7057_RS08265	COG4464	protein tyrosine phosphatase activity
G7057_RS08320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G7057_RS08325	COG1316	TRANSCRIPTIONal
G7057_RS08330	COG1316	TRANSCRIPTIONal
G7057_RS08335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7057_RS08345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7057_RS08360	COG1086	Polysaccharide biosynthesis protein
G7057_RS08380	COG0438	transferase activity, transferring glycosyl groups
G7057_RS08400	COG0860	N-Acetylmuramoyl-L-alanine amidase
G7057_RS08405	COG1705	Flagellar rod assembly protein muramidase FlgJ
G7057_RS08405	COG1388	LysM domain
G7057_RS08415	COG0463	Glycosyl transferase, family 2
G7057_RS08440	COG0366	Alpha amylase catalytic
G7057_RS08460	COG5632	N-Acetylmuramoyl-L-alanine amidase
G7057_RS08460	COG5263	repeat protein
G7057_RS08490	COG2137	regulation of response to DNA damage stimulus
G7057_RS08495	COG1194	a g-specific adenine glycosylase
G7057_RS08500	COG3557	Belongs to the UPF0374 family
G7057_RS08510	COG1523	belongs to the glycosyl hydrolase 13 family
G7057_RS08515	COG0561	phosphatase activity
G7057_RS08520	COG4129	membrane
G7057_RS08525	COG0735	belongs to the Fur family
G7057_RS08530	COG1609	Transcriptional regulator
G7057_RS08535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G7057_RS08540	COG0366	Alpha amylase catalytic
G7057_RS08545	COG0366	Alpha amylase catalytic
G7057_RS08550	COG2182	Extracellular solute-binding protein
G7057_RS08560	COG3833	ABC-type maltose transport systems, permease component
G7057_RS08575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7057_RS08650	COG1902	pentaerythritol trinitrate reductase activity
G7057_RS08675	COG0500	methyltransferase
G7057_RS08680	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G7057_RS08685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7057_RS08690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7057_RS08695	COG0656	L-ascorbic acid biosynthetic process
G7057_RS08700	COG1253	flavin adenine dinucleotide binding
G7057_RS08705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7057_RS08710	COG3679	Belongs to the UPF0342 family
G7057_RS08715	COG0420	3'-5' exonuclease activity
G7057_RS08720	COG4717	serine-type aminopeptidase activity
G7057_RS08730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7057_RS08740	COG0537	adenosine 5'-monophosphoramidase activity
G7057_RS08745	COG1131	(ABC) transporter
G7057_RS08750	COG4473	ABC transporter
G7057_RS08755	COG0510	thiamine kinase activity
G7057_RS08770	COG1363	Peptidase, m42
G7057_RS08775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7057_RS08780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7057_RS08790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7057_RS08800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7057_RS08800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7057_RS08805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7057_RS08810	COG0237	dephospho-CoA kinase activity
G7057_RS08815	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7057_RS08820	COG3611	Membrane attachment protein
G7057_RS08825	COG1484	DNA-dependent DNA replication
G7057_RS08830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G7057_RS08835	COG1473	amidohydrolase
G7057_RS08840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7057_RS08850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7057_RS08865	COG1846	Transcriptional regulator
G7057_RS08870	COG0604	alcohol dehydrogenase
G7057_RS08875	COG0778	Nitroreductase
G7057_RS08885	COG3759	membrane
G7057_RS08900	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G7057_RS08915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7057_RS08930	COG1234	tRNA 3'-trailer cleavage
G7057_RS08935	COG0095	Lipoate-protein ligase
G7057_RS08940	COG0180	Tryptophanyl-tRNA synthetase
G7057_RS08945	COG1393	Belongs to the ArsC family
G7057_RS08950	COG0583	DNA-binding transcription factor activity
G7057_RS08960	COG1346	cytolysis
G7057_RS08965	COG1304	FMN binding
G7057_RS08970	COG4862	establishment of competence for transformation
G7057_RS08985	COG1164	Oligoendopeptidase f
G7057_RS08995	COG4116	CYTH
G7057_RS09000	COG2357	RelA SpoT domain protein
G7057_RS09005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G7057_RS09015	COG0564	pseudouridine synthase activity
G7057_RS09020	COG2239	Acts as a magnesium transporter
G7057_RS09030	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7057_RS09035	COG1253	flavin adenine dinucleotide binding
G7057_RS09040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7057_RS09050	COG0542	response to heat
G7057_RS09055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7057_RS09060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7057_RS09065	COG0438	transferase activity, transferring glycosyl groups
G7057_RS09070	COG2084	Dehydrogenase
G7057_RS09075	COG4703	Protein of unknown function (DUF1797)
G7057_RS09080	COG0460	homoserine dehydrogenase
G7057_RS09085	COG0083	homoserine kinase activity
G7057_RS09090	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G7057_RS09095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G7057_RS09100	COG1534	Rna-binding protein
G7057_RS09105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G7057_RS09110	COG1713	HD superfamily hydrolase involved in NAD metabolism
G7057_RS09115	COG0799	negative regulation of ribosome biogenesis
G7057_RS09120	COG2226	methyltransferase
G7057_RS09125	COG1323	Belongs to the UPF0348 family
G7057_RS09135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7057_RS09150	COG0505	Belongs to the CarA family
G7057_RS09155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7057_RS09160	COG2001	Belongs to the MraZ family
G7057_RS09165	COG0275	rRNA processing
G7057_RS09180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7057_RS09185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7057_RS09190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G7057_RS09195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G7057_RS09200	COG0849	cell division
G7057_RS09210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G7057_RS09215	COG1799	cell septum assembly
G7057_RS09225	COG2302	S4 RNA-binding domain
G7057_RS09230	COG3599	regulation of cell shape
G7057_RS09235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G7057_RS09245	COG2261	transglycosylase associated protein
G7057_RS09250	COG3853	Toxic anion resistance protein (TelA)
G7057_RS09260	COG0494	nUDIX hydrolase
G7057_RS09300	COG0582	viral genome integration into host DNA
G7057_RS09350	COG1484	DNA-dependent DNA replication
G7057_RS09360	COG3728	DNA packaging
G7057_RS09360	COG5484	DNA packaging
G7057_RS09405	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G7057_RS09410	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
G7057_RS09415	COG1104	cysteine desulfurase activity
G7057_RS09420	COG0301	tRNA thio-modification
G7057_RS09425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G7057_RS09430	COG0525	valine-tRNA ligase activity
G7057_RS09435	COG0285	dihydrofolate synthase activity
G7057_RS09440	COG2003	Belongs to the UPF0758 family
G7057_RS09450	COG1278	Cold shock
G7057_RS09455	COG1077	Cell shape determining protein MreB Mrl
G7057_RS09460	COG1792	Involved in formation and maintenance of cell shape
G7057_RS09475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7057_RS09495	COG0765	amino acid transport
G7057_RS09500	COG1126	abc transporter atp-binding protein
G7057_RS09505	COG2814	Major facilitator Superfamily
G7057_RS09510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G7057_RS09515	COG2868	ribosomal protein
G7057_RS09525	COG0827	DNA restriction-modification system
G7057_RS09530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G7057_RS09550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7057_RS09565	COG1104	cysteine desulfurase activity
G7057_RS09585	COG0482	sulfurtransferase activity
G7057_RS09590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G7057_RS09595	COG1597	lipid kinase activity
G7057_RS09600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7057_RS09605	COG4472	Bacterial protein of unknown function (DUF965)
G7057_RS09610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7057_RS09615	COG3906	Belongs to the UPF0473 family
G7057_RS09620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G7057_RS09625	COG0572	uridine kinase
G7057_RS09630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7057_RS09640	COG4585	Histidine kinase
G7057_RS09645	COG2197	response regulator
G7057_RS09655	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G7057_RS09675	COG0242	peptide deformylase activity
G7057_RS09680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G7057_RS09705	COG4476	Belongs to the UPF0223 family
G7057_RS09710	COG0483	inositol monophosphate 1-phosphatase activity
G7057_RS09720	COG4838	Belongs to the UPF0358 family
G7057_RS09725	COG0772	Belongs to the SEDS family
G7057_RS09735	COG3679	Belongs to the UPF0342 family
G7057_RS09740	COG4471	UPF0298 protein
G7057_RS09745	COG0742	ribosomal rna small subunit methyltransferase
G7057_RS09750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G7057_RS09755	COG1596	polysaccharide export
G7057_RS09755	COG1555	photosystem II stabilization
G7057_RS09760	COG2131	deaminase
G7057_RS09765	COG2333	competence protein COMEC
G7057_RS09765	COG0658	competence protein
G7057_RS09770	COG1466	dna polymerase III delta subunit
G7057_RS09775	COG0268	Binds directly to 16S ribosomal RNA
G7057_RS09780	COG0556	nucleotide-excision repair
G7057_RS09785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7057_RS09790	COG1185	polyribonucleotide nucleotidyltransferase activity
G7057_RS09795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7057_RS09825	COG1269	ATP hydrolysis coupled proton transport
G7057_RS09830	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7057_RS09840	COG1527	subunit (C
G7057_RS09845	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
G7057_RS09850	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
G7057_RS09855	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
G7057_RS09860	COG1394	ATPase activity, coupled to movement of substances
G7057_RS09865	COG0194	GDP metabolic process
G7057_RS09870	COG1758	RNA polymerase activity
G7057_RS09875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7057_RS09880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G7057_RS09885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7057_RS09885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7057_RS09895	COG2815	serine threonine protein kinase
G7057_RS09895	COG0515	serine threonine protein kinase
G7057_RS09900	COG1162	GTPase activity
G7057_RS09905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G7057_RS09910	COG1564	THIamine pyrophosphokinase
G7057_RS09920	COG1302	Protein conserved in bacteria
G7057_RS09925	COG1461	Dihydroxyacetone kinase
G7057_RS09930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G7057_RS09935	COG0416	fatty acid biosynthetic process
G7057_RS09950	COG4608	Belongs to the ABC transporter superfamily
G7057_RS09955	COG0601	transmembrane transport
G7057_RS09960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7057_RS09970	COG0571	ribonuclease III activity
G7057_RS09975	COG1196	nuclear chromosome segregation
G7057_RS09980	COG0561	phosphatase activity
G7057_RS09985	COG0552	protein localization to endoplasmic reticulum
G7057_RS09990	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
G7057_RS09995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7057_RS10000	COG0228	four-way junction DNA binding
G7057_RS10005	COG1837	Belongs to the UPF0109 family
G7057_RS10010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7057_RS10015	COG0336	Belongs to the RNA methyltransferase TrmD family
G7057_RS10020	COG0335	large ribosomal subunit rRNA binding
G7057_RS10025	COG1733	regulation of RNA biosynthetic process
G7057_RS10045	COG0561	phosphatase activity
G7057_RS10055	COG2151	metal-sulfur cluster biosynthetic enzyme
G7057_RS10065	COG0542	response to heat
G7057_RS10070	COG1030	water channel activity
G7057_RS10075	COG4864	UPF0365 protein
G7057_RS10095	COG0343	queuine tRNA-ribosyltransferase activity
G7057_RS10100	COG1862	Preprotein translocase
G7057_RS10110	COG1012	belongs to the aldehyde dehydrogenase family
G7057_RS10110	COG1454	alcohol dehydrogenase
G7057_RS10115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7057_RS10125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G7057_RS10130	COG4109	DRTGG domain
G7057_RS10135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7057_RS10140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G7057_RS10145	COG0513	Belongs to the DEAD box helicase family
G7057_RS10155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G7057_RS10180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7057_RS10185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7057_RS10195	COG1940	carbohydrate kinase activity
G7057_RS10215	COG0745	RESPONSE REGULATOR receiver
G7057_RS10220	COG5002	protein histidine kinase activity
G7057_RS10225	COG0706	membrane insertase activity
G7057_RS10240	COG1674	ftsk spoiiie
G7057_RS10240	COG1280	lysine exporter protein (LysE YggA)
G7057_RS10245	COG1744	ABC transporter substrate-binding protein PnrA-like
G7057_RS10265	COG0612	Peptidase, M16
G7057_RS10270	COG0612	Peptidase, M16
G7057_RS10275	COG0300	oxidoreductase activity
G7057_RS10280	COG1426	Protein conserved in bacteria
G7057_RS10285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7057_RS10290	COG1546	Belongs to the CinA family
G7057_RS10290	COG1058	Belongs to the CinA family
G7057_RS10295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7057_RS10305	COG1692	metallophosphoesterase
G7057_RS10315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G7057_RS10320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7057_RS10330	COG0632	four-way junction helicase activity
G7057_RS10335	COG2255	four-way junction helicase activity
G7057_RS10340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G7057_RS10350	COG0587	DNA-directed DNA polymerase activity
G7057_RS10355	COG0205	6-phosphofructokinase activity
G7057_RS10365	COG2996	Protein conserved in bacteria
G7057_RS10370	COG0735	belongs to the Fur family
G7057_RS10380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G7057_RS10385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G7057_RS10390	COG0456	acetyltransferase
G7057_RS10395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G7057_RS10400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G7057_RS10405	COG1187	pseudouridine synthase activity
G7057_RS10410	COG0745	RESPONSE REGULATOR receiver
G7057_RS10415	COG5002	protein histidine kinase activity
G7057_RS10420	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G7057_RS10435	COG0514	ATP-dependent DNA helicase (RecQ)
G7057_RS10440	COG1388	LysM domain
G7057_RS10440	COG1705	Flagellar rod assembly protein muramidase FlgJ
G7057_RS10450	COG0539	negative regulation of cytoplasmic translation
G7057_RS10455	COG1160	GTP binding
G7057_RS10465	COG0457	Tetratricopeptide repeat
G7057_RS10470	COG5582	Belongs to the UPF0302 family
G7057_RS10475	COG0617	tRNA 3'-terminal CCA addition
G7057_RS10485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7057_RS10485	COG1199	ATP-dependent helicase activity
G7057_RS10515	COG3331	DNA recombination
G7057_RS10520	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7057_RS10525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7057_RS10530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G7057_RS10535	COG2270	Major facilitator Superfamily
G7057_RS10540	COG0358	DNA primase activity
G7057_RS10545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7057_RS10550	COG2384	SAM-dependent methyltransferase
G7057_RS10555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G7057_RS10560	COG2195	Cleaves the N-terminal amino acid of tripeptides
G7057_RS10570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G7057_RS10575	COG0196	riboflavin kinase activity
G7057_RS10580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7057_RS10590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7057_RS10595	COG0443	Heat shock 70 kDa protein
G7057_RS10600	COG0484	heat shock protein binding
G7057_RS10605	COG0481	GTPase activity
G7057_RS10615	COG2268	Band 7 protein
G7057_RS10620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G7057_RS10625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G7057_RS10630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7057_RS10640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7057_RS10650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7057_RS10655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G7057_RS10660	COG0138	bifunctional purine biosynthesis protein purh
G7057_RS10665	COG0151	Belongs to the GarS family
G7057_RS10670	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G7057_RS10675	COG0488	(ABC) transporter
G7057_RS10680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G7057_RS10700	COG1272	protein, Hemolysin III
G7057_RS10715	COG0813	purine-nucleoside phosphorylase activity
G7057_RS10720	COG3409	Peptidoglycan-binding domain 1 protein
G7057_RS10720	COG0793	Belongs to the peptidase S41A family
G7057_RS10725	COG0681	Belongs to the peptidase S26 family
G7057_RS10740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G7057_RS10745	COG0758	DNA mediated transformation
G7057_RS10750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7057_RS10755	COG4974	Belongs to the 'phage' integrase family
G7057_RS10760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G7057_RS10765	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G7057_RS10770	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G7057_RS10780	COG0187	DNA topoisomerase II activity
G7057_RS10785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G7057_RS10795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G7057_RS10800	COG1227	inorganic diphosphatase activity
G7057_RS10815	COG2514	catechol 2,3-dioxygenase activity
G7057_RS10830	COG0765	amino acid transport
G7057_RS10835	COG1126	abc transporter atp-binding protein
G7057_RS10840	COG0697	spore germination
G7057_RS10845	COG2151	metal-sulfur cluster biosynthetic enzyme
G7057_RS10850	COG0129	dihydroxy-acid dehydratase activity
G7057_RS10855	COG0028	Belongs to the TPP enzyme family
G7057_RS10860	COG0440	acetolactate synthase activity
G7057_RS10865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7057_RS10870	COG1119	ATPase activity
G7057_RS10875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G7057_RS10880	COG0251	oxidation-reduction process
G7057_RS10885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7057_RS10900	COG1363	Peptidase, m42
G7057_RS10955	COG1131	(ABC) transporter
G7057_RS10960	COG2197	response regulator
G7057_RS10965	COG4585	Histidine kinase
G7057_RS10970	COG0431	NADPH-dependent FMN reductase
G7057_RS11000	COG3177	Filamentation induced by cAMP protein fic
G7057_RS11005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G7057_RS11010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G7057_RS11030	COG4120	Belongs to the binding-protein-dependent transport system permease family
G7057_RS11040	COG1293	RNA-binding protein homologous to eukaryotic snRNP
G7057_RS11060	COG0564	pseudouridine synthase activity
G7057_RS11065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G7057_RS11085	COG1074	ATP-dependent DNA helicase activity
G7057_RS11095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G7057_RS11110	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G7057_RS11115	COG0195	Participates in both transcription termination and antitermination
G7057_RS11120	COG0779	Required for maturation of 30S ribosomal subunits
G7057_RS11130	COG0750	zinc metalloprotease
G7057_RS11135	COG4589	Belongs to the CDS family
G7057_RS11140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7057_RS11145	COG0233	cytoplasmic translational termination
G7057_RS11150	COG0528	UMP kinase activity
G7057_RS11155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G7057_RS11160	COG0052	Belongs to the universal ribosomal protein uS2 family
G7057_RS11165	COG0204	Acyl-transferase
G7057_RS11170	COG1132	(ABC) transporter
G7057_RS11175	COG1132	(ABC) transporter
G7057_RS11180	COG3763	UPF0154 protein
G7057_RS11185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7057_RS11190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7057_RS11195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G7057_RS11195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G7057_RS11205	COG1234	tRNA 3'-trailer cleavage
G7057_RS11210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7057_RS11215	COG0751	glycine-tRNA ligase activity
G7057_RS11220	COG0752	glycyl-tRNA synthetase alpha subunit
G7057_RS11225	COG1381	Involved in DNA repair and RecF pathway recombination
G7057_RS11230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G7057_RS11235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7057_RS11240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7057_RS11245	COG1702	phosphate starvation-inducible protein PhoH
G7057_RS11255	COG0735	belongs to the Fur family
G7057_RS11260	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G7057_RS11265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G7057_RS11270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G7057_RS11275	COG0124	histidyl-tRNA synthetase
G7057_RS11280	COG0860	N-Acetylmuramoyl-L-alanine amidase
G7057_RS11280	COG3103	Sh3 type 3 domain protein
G7057_RS11280	COG4991	sh3 domain protein
G7057_RS11285	COG1490	D-aminoacyl-tRNA deacylase activity
G7057_RS11290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7057_RS11295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G7057_RS11300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G7057_RS11305	COG2264	protein methyltransferase activity
G7057_RS11320	COG3599	regulation of cell shape
G7057_RS11330	COG0116	Belongs to the methyltransferase superfamily
G7057_RS11335	COG0328	RNA-DNA hybrid ribonuclease activity
G7057_RS11350	COG0825	malonyl-CoA metabolic process
G7057_RS11355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G7057_RS11360	COG0439	Biotin carboxylase
G7057_RS11365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7057_RS11370	COG0511	ligase activity, forming carbon-carbon bonds
G7057_RS11375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7057_RS11385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G7057_RS11395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7057_RS11400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7057_RS11420	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
G7057_RS11425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7057_RS11430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7057_RS11435	COG0584	glycerophosphoryl diester phosphodiesterase
G7057_RS11440	COG0497	DNA recombination
G7057_RS11445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G7057_RS11460	COG1570	exodeoxyribonuclease VII activity
G7057_RS11465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7057_RS11470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7057_RS11475	COG1302	Protein conserved in bacteria
G7057_RS11485	COG0006	proline dipeptidase activity
G7057_RS11510	COG4537	Required for transformation and DNA binding
G7057_RS11520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7057_RS11525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G7057_RS11530	COG0217	transcriptional regulatory protein
G7057_RS11540	COG1597	lipid kinase activity
G7057_RS11555	COG1609	Transcriptional regulator
G7057_RS11565	COG4980	gas vesicle protein
G7057_RS11575	COG0668	transmembrane transport
G7057_RS11590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7057_RS11600	COG1719	4-vinyl reductase, 4VR
G7057_RS11605	COG3118	belongs to the thioredoxin family
G7057_RS11610	COG1193	negative regulation of DNA recombination
G7057_RS11615	COG1286	toxin biosynthetic process
G7057_RS11620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G7057_RS11635	COG0072	phenylalanine-tRNA ligase activity
G7057_RS11635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7057_RS11640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7057_RS11645	COG1733	regulation of RNA biosynthetic process
G7057_RS11655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7057_RS11660	COG1196	nuclear chromosome segregation
G7057_RS11660	COG0741	lytic transglycosylase activity
G7057_RS11660	COG0739	heme binding
G7057_RS11670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7057_RS11675	COG1187	pseudouridine synthase activity
G7057_RS11680	COG2244	polysaccharide biosynthetic process
G7057_RS11685	COG0726	polysaccharide deacetylase
G7057_RS11690	COG0495	leucyl-tRNA aminoacylation
G7057_RS11695	COG1705	Flagellar rod assembly protein muramidase FlgJ
G7057_RS11695	COG1388	LysM domain
G7057_RS11700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
G7057_RS11715	COG1609	Transcriptional regulator
G7057_RS11715	COG2207	Transcriptional regulator
G7057_RS11720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme