locus-tag	class	description
KKOR_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KKOR_RS00010	COG0592	DNA-directed DNA polymerase activity
KKOR_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KKOR_RS00025	COG2326	polyphosphate kinase activity
KKOR_RS00035	COG0433	COG0433 Predicted ATPase
KKOR_RS00040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KKOR_RS00050	COG3094	Invasion gene expression up-regulator, SirB
KKOR_RS00055	COG1739	Uncharacterized protein family UPF0029
KKOR_RS00060	COG0006	proline dipeptidase activity
KKOR_RS00065	COG1250	3-hydroxyacyl-CoA dehydrogenase
KKOR_RS00065	COG1024	Enoyl-CoA hydratase
KKOR_RS00070	COG0183	Belongs to the thiolase family
KKOR_RS00110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKOR_RS00115	COG0640	Transcriptional regulator
KKOR_RS00140	COG1404	Belongs to the peptidase S8 family
KKOR_RS00155	COG0606	chelatase, subunit chli
KKOR_RS00300	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KKOR_RS00320	COG0210	DNA helicase
KKOR_RS00340	COG0606	chelatase, subunit chli
KKOR_RS00360	COG2205	protein histidine kinase activity
KKOR_RS00365	COG0745	RESPONSE REGULATOR receiver
KKOR_RS00375	COG3706	GGDEF domain
KKOR_RS00400	COG4628	conserved protein (DUF2132)
KKOR_RS00410	COG1725	Transcriptional regulator
KKOR_RS00415	COG1131	(ABC) transporter
KKOR_RS00430	COG0513	Belongs to the DEAD box helicase family
KKOR_RS00455	COG3655	Transcriptional regulator
KKOR_RS00480	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KKOR_RS00515	COG3738	Protein conserved in bacteria
KKOR_RS00520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KKOR_RS00530	COG3706	GGDEF domain
KKOR_RS00540	COG0384	phenazine biosynthesis protein PhzF
KKOR_RS00550	COG0431	NADPH-dependent FMN reductase
KKOR_RS00560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KKOR_RS00580	COG1253	flavin adenine dinucleotide binding
KKOR_RS00610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KKOR_RS00625	COG2022	thiamine diphosphate biosynthetic process
KKOR_RS00630	COG0352	thiamine-phosphate diphosphorylase activity
KKOR_RS00635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKOR_RS00645	COG3428	Bacterial PH domain
KKOR_RS00655	COG1063	alcohol dehydrogenase
KKOR_RS00660	COG2153	protein acetylation
KKOR_RS00670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKOR_RS00690	COG0583	DNA-binding transcription factor activity
KKOR_RS00695	COG3161	chorismate lyase activity
KKOR_RS00700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KKOR_RS00705	COG2937	Belongs to the GPAT DAPAT family
KKOR_RS00765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KKOR_RS00785	COG1757	Na H antiporter
KKOR_RS00805	COG3071	HemY protein
KKOR_RS00810	COG2959	enzyme of heme biosynthesis
KKOR_RS00820	COG0181	hydroxymethylbilane synthase activity
KKOR_RS00840	COG0400	carboxylic ester hydrolase activity
KKOR_RS00855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KKOR_RS00870	COG1011	Hydrolase
KKOR_RS00880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKOR_RS00885	COG3971	2-oxopent-4-enoate hydratase activity
KKOR_RS00890	COG0210	DNA helicase
KKOR_RS00910	COG1404	Belongs to the peptidase S8 family
KKOR_RS00915	COG1404	Belongs to the peptidase S8 family
KKOR_RS00925	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KKOR_RS00930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KKOR_RS00935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KKOR_RS00990	COG0515	serine threonine protein kinase
KKOR_RS01000	COG0330	HflC and HflK could
KKOR_RS01015	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KKOR_RS01020	COG1194	a g-specific adenine glycosylase
KKOR_RS01025	COG0471	metal ion transport
KKOR_RS01025	COG3273	potassium ion transport
KKOR_RS01030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KKOR_RS01040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KKOR_RS01045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KKOR_RS01060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KKOR_RS01065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KKOR_RS01080	COG5001	Diguanylate cyclase
KKOR_RS01080	COG1716	ATPase activity
KKOR_RS01095	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KKOR_RS01100	COG0189	ligase activity
KKOR_RS01120	COG0840	transmembrane signaling receptor activity
KKOR_RS01130	COG0643	Histidine kinase
KKOR_RS01130	COG2198	Histidine kinase
KKOR_RS01130	COG0784	Response regulator, receiver
KKOR_RS01135	COG2201	protein-glutamate methylesterase activity
KKOR_RS01145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KKOR_RS01160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KKOR_RS01165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KKOR_RS01170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KKOR_RS01185	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KKOR_RS01190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKOR_RS01215	COG0151	Belongs to the GarS family
KKOR_RS01225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KKOR_RS01230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KKOR_RS01240	COG2264	protein methyltransferase activity
KKOR_RS01250	COG0439	Biotin carboxylase
KKOR_RS01255	COG0511	ligase activity, forming carbon-carbon bonds
KKOR_RS01260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KKOR_RS01265	COG0745	RESPONSE REGULATOR receiver
KKOR_RS01270	COG0697	spore germination
KKOR_RS01280	COG4232	protein-disulfide reductase activity
KKOR_RS01305	COG1324	tolerance protein
KKOR_RS01310	COG3030	protein affecting phage T7 exclusion by the F plasmid
KKOR_RS01315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KKOR_RS01320	COG0459	protein refolding
KKOR_RS01330	COG0288	reversible hydration of carbon dioxide
KKOR_RS01340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KKOR_RS01345	COG0456	acetyltransferase
KKOR_RS01350	COG2304	oxidoreductase activity
KKOR_RS01365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KKOR_RS01370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKOR_RS01375	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KKOR_RS01385	COG3128	pkhd-type hydroxylase
KKOR_RS01400	COG0429	hydrolase of the alpha beta-hydrolase fold
KKOR_RS01405	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KKOR_RS01420	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KKOR_RS01425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KKOR_RS01430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KKOR_RS01435	COG0649	NAD binding
KKOR_RS01440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KKOR_RS01450	COG1034	ATP synthesis coupled electron transport
KKOR_RS01455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KKOR_RS01460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KKOR_RS01470	COG0713	ATP synthesis coupled electron transport
KKOR_RS01485	COG1007	ATP synthesis coupled electron transport
KKOR_RS01495	COG0779	Required for maturation of 30S ribosomal subunits
KKOR_RS01500	COG0195	Participates in both transcription termination and antitermination
KKOR_RS01505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKOR_RS01510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KKOR_RS01515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KKOR_RS01525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KKOR_RS01530	COG1185	polyribonucleotide nucleotidyltransferase activity
KKOR_RS01550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKOR_RS01560	COG1702	phosphate starvation-inducible protein PhoH
KKOR_RS01565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KKOR_RS01570	COG4535	Mg2 and Co2 transporter CorC
KKOR_RS01575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KKOR_RS01590	COG0495	leucyl-tRNA aminoacylation
KKOR_RS01605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KKOR_RS01620	COG0768	penicillin binding
KKOR_RS01625	COG0772	Belongs to the SEDS family
KKOR_RS01630	COG2951	lytic endotransglycosylase activity
KKOR_RS01640	COG1686	Belongs to the peptidase S11 family
KKOR_RS01645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KKOR_RS01650	COG2921	Belongs to the UPF0250 family
KKOR_RS01655	COG0321	lipoyl(octanoyl) transferase activity
KKOR_RS01690	COG0586	Pfam SNARE associated Golgi protein
KKOR_RS01695	COG1280	lysine exporter protein (LysE YggA)
KKOR_RS01700	COG2205	protein histidine kinase activity
KKOR_RS01705	COG0745	RESPONSE REGULATOR receiver
KKOR_RS01720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KKOR_RS01725	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KKOR_RS01730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KKOR_RS01735	COG1428	Deoxynucleoside kinase
KKOR_RS01740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KKOR_RS01745	COG0617	tRNA 3'-terminal CCA addition
KKOR_RS01750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKOR_RS01755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KKOR_RS01765	COG5001	Diguanylate cyclase
KKOR_RS01775	COG1073	alpha beta
KKOR_RS01785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KKOR_RS01835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KKOR_RS01840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KKOR_RS01855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKOR_RS01860	COG3844	kynureninase activity
KKOR_RS01885	COG1666	GTP binding
KKOR_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
KKOR_RS01935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KKOR_RS01940	COG0540	Belongs to the ATCase OTCase family
KKOR_RS01945	COG1773	rubredoxin
KKOR_RS01965	COG3647	Membrane
KKOR_RS01970	COG0625	glutathione transferase activity
KKOR_RS01975	COG1595	DNA-templated transcription, initiation
KKOR_RS01985	COG0393	Putative heavy-metal-binding
KKOR_RS02000	COG3739	integral membrane protein
KKOR_RS02005	COG0038	chloride channel
KKOR_RS02020	COG0316	Belongs to the HesB IscA family
KKOR_RS02030	COG4942	peptidase
KKOR_RS02035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KKOR_RS02075	COG0513	Belongs to the DEAD box helicase family
KKOR_RS02085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KKOR_RS02090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KKOR_RS02125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KKOR_RS02145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KKOR_RS02150	COG0081	regulation of translation
KKOR_RS02155	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KKOR_RS02160	COG0222	ribosome binding
KKOR_RS02165	COG0085	RNA polymerase activity
KKOR_RS02170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKOR_RS02175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KKOR_RS02180	COG0049	tRNA binding
KKOR_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KKOR_RS02190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KKOR_RS02195	COG0051	transcription antitermination factor activity, RNA binding
KKOR_RS02200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KKOR_RS02205	COG0088	Forms part of the polypeptide exit tunnel
KKOR_RS02210	COG0089	rRNA binding
KKOR_RS02220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KKOR_RS02225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KKOR_RS02230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KKOR_RS02235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KKOR_RS02240	COG0255	Belongs to the universal ribosomal protein uL29 family
KKOR_RS02245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KKOR_RS02250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KKOR_RS02255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KKOR_RS02265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKOR_RS02270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KKOR_RS02275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KKOR_RS02285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KKOR_RS02290	COG1841	ribosomal large subunit assembly
KKOR_RS02295	COG0200	Binds to the 23S rRNA
KKOR_RS02300	COG0201	protein transport
KKOR_RS02305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KKOR_RS02310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KKOR_RS02315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KKOR_RS02330	COG0203	ribosomal protein L17
KKOR_RS02345	COG1230	cation diffusion facilitator family transporter
KKOR_RS02360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KKOR_RS02365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKOR_RS02370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KKOR_RS02370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KKOR_RS02385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KKOR_RS02390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKOR_RS02395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KKOR_RS02400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KKOR_RS02415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KKOR_RS02430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KKOR_RS02435	COG0142	geranyltranstransferase activity
KKOR_RS02440	COG1722	exodeoxyribonuclease VII activity
KKOR_RS02445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKOR_RS02465	COG0488	(ABC) transporter
KKOR_RS02485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KKOR_RS02505	COG4772	TonB-dependent receptor
KKOR_RS02515	COG3098	single-species biofilm formation
KKOR_RS02545	COG2204	response regulator
KKOR_RS02550	COG3038	cytochrome b561
KKOR_RS02555	COG0688	phosphatidylethanolamine metabolic process
KKOR_RS02565	COG2154	pterin-4-alpha-carbinolamine dehydratase
KKOR_RS02570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KKOR_RS02575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KKOR_RS02575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KKOR_RS02580	COG0802	atpase or kinase
KKOR_RS02585	COG0860	N-Acetylmuramoyl-L-alanine amidase
KKOR_RS02590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KKOR_RS02595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KKOR_RS02600	COG1923	regulation of RNA biosynthetic process
KKOR_RS02605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KKOR_RS02610	COG0330	HflC and HflK could
KKOR_RS02615	COG0330	HflC and HflK could
KKOR_RS02625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KKOR_RS02630	COG2311	Membrane
KKOR_RS02640	COG3384	dioxygenase
KKOR_RS02680	COG3278	Belongs to the heme-copper respiratory oxidase family
KKOR_RS02695	COG2010	Cytochrome c
KKOR_RS02700	COG0348	domain, Protein
KKOR_RS02710	COG2217	Heavy metal translocating P-type atpase
KKOR_RS02725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KKOR_RS02730	COG0137	argininosuccinate synthase activity
KKOR_RS02735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KKOR_RS02740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KKOR_RS02745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KKOR_RS02750	COG0165	Argininosuccinate lyase
KKOR_RS02775	COG2318	DinB family
KKOR_RS02790	COG0557	exoribonuclease II activity
KKOR_RS02795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKOR_RS02810	COG1984	allophanate hydrolase subunit 2
KKOR_RS02815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KKOR_RS02825	COG1914	H( )-stimulated, divalent metal cation uptake system
KKOR_RS02835	COG1522	sequence-specific DNA binding
KKOR_RS02855	COG0360	Binds together with S18 to 16S ribosomal RNA
KKOR_RS02865	COG0359	binds to the 23S rRNA
KKOR_RS02880	COG3011	Protein conserved in bacteria
KKOR_RS02900	COG0305	Participates in initiation and elongation during chromosome replication
KKOR_RS02905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KKOR_RS02910	COG0432	Pfam Uncharacterised protein family UPF0047
KKOR_RS02920	COG0501	Belongs to the peptidase M48B family
KKOR_RS02930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KKOR_RS02960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKOR_RS02965	COG0179	Fumarylacetoacetate (FAA) hydrolase
KKOR_RS02980	COG1595	DNA-templated transcription, initiation
KKOR_RS02990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KKOR_RS02995	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KKOR_RS03010	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KKOR_RS03015	COG0205	6-phosphofructokinase activity
KKOR_RS03020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KKOR_RS03025	COG0163	prenyltransferase activity
KKOR_RS03030	COG1131	(ABC) transporter
KKOR_RS03035	COG0842	Transport permease protein
KKOR_RS03060	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KKOR_RS03070	COG1368	sulfuric ester hydrolase activity
KKOR_RS03085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KKOR_RS03090	COG1064	alcohol dehydrogenase
KKOR_RS03095	COG0513	Belongs to the DEAD box helicase family
KKOR_RS03130	COG0012	GTP binding
KKOR_RS03135	COG0193	aminoacyl-tRNA hydrolase activity
KKOR_RS03145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKOR_RS03155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KKOR_RS03170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KKOR_RS03180	COG2890	protein-(glutamine-N5) methyltransferase activity
KKOR_RS03185	COG1077	Cell shape determining protein MreB Mrl
KKOR_RS03190	COG1792	Involved in formation and maintenance of cell shape
KKOR_RS03195	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KKOR_RS03200	COG0424	maF-like protein
KKOR_RS03205	COG1530	ribonuclease E activity
KKOR_RS03220	COG0312	modulator of DNA gyrase
KKOR_RS03225	COG3028	Belongs to the UPF0307 family
KKOR_RS03235	COG0312	modulator of DNA gyrase
KKOR_RS03240	COG2239	Acts as a magnesium transporter
KKOR_RS03245	COG1660	Displays ATPase and GTPase activities
KKOR_RS03250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KKOR_RS03265	COG1137	ATPase activity
KKOR_RS03280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KKOR_RS03300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKOR_RS03305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKOR_RS03330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KKOR_RS03340	COG0776	regulation of translation
KKOR_RS03345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KKOR_RS03350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KKOR_RS03355	COG0723	plastoquinol--plastocyanin reductase activity
KKOR_RS03360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KKOR_RS03365	COG2857	Cytochrome c1
KKOR_RS03370	COG0625	glutathione transferase activity
KKOR_RS03375	COG2969	positive regulation of protein catabolic process
KKOR_RS03385	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KKOR_RS03390	COG0792	nuclease activity
KKOR_RS03395	COG3107	peptidoglycan biosynthetic process
KKOR_RS03415	COG2066	Belongs to the glutaminase family
KKOR_RS03425	COG0275	rRNA processing
KKOR_RS03430	COG3116	cell division
KKOR_RS03435	COG0768	penicillin binding
KKOR_RS03445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KKOR_RS03450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKOR_RS03455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KKOR_RS03460	COG0772	Belongs to the SEDS family
KKOR_RS03465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KKOR_RS03470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KKOR_RS03475	COG1181	Belongs to the D-alanine--D-alanine ligase family
KKOR_RS03480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KKOR_RS03495	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KKOR_RS03505	COG0739	heme binding
KKOR_RS03520	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KKOR_RS03525	COG3023	N-Acetylmuramoyl-L-alanine amidase
KKOR_RS03560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KKOR_RS03565	COG0237	dephospho-CoA kinase activity
KKOR_RS03570	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KKOR_RS03585	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKOR_RS03590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KKOR_RS03595	COG0697	spore germination
KKOR_RS03610	COG3590	peptidase
KKOR_RS03625	COG0700	Nucleoside recognition
KKOR_RS03630	COG2813	Specifically methylates the guanine in position
KKOR_RS03635	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KKOR_RS03640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KKOR_RS03640	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KKOR_RS03645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KKOR_RS03650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KKOR_RS03655	COG0175	sulfate reduction
KKOR_RS03660	COG1648	precorrin-2 dehydrogenase activity
KKOR_RS03660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KKOR_RS03665	COG3104	oligopeptide transport
KKOR_RS03675	COG0604	alcohol dehydrogenase
KKOR_RS03685	COG1074	ATP-dependent DNA helicase activity
KKOR_RS03705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KKOR_RS03710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KKOR_RS03735	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KKOR_RS03765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKOR_RS03770	COG0481	GTPase activity
KKOR_RS03775	COG0681	Belongs to the peptidase S26 family
KKOR_RS03785	COG0571	ribonuclease III activity
KKOR_RS03790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KKOR_RS03795	COG1381	Involved in DNA repair and RecF pathway recombination
KKOR_RS03800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KKOR_RS03820	COG0386	Belongs to the glutathione peroxidase family
KKOR_RS03830	COG1863	multisubunit Na H antiporter MnhE subunit
KKOR_RS03835	COG2212	antiporter activity
KKOR_RS03850	COG1006	Multisubunit Na H antiporter MnhC subunit
KKOR_RS03855	COG0651	ATP synthesis coupled electron transport
KKOR_RS03860	COG0651	ATP synthesis coupled electron transport
KKOR_RS03870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KKOR_RS03870	COG2111	Na H antiporter
KKOR_RS03880	COG3710	Transcriptional regulator
KKOR_RS03900	COG0616	signal peptide processing
KKOR_RS03905	COG0500	methyltransferase
KKOR_RS03920	COG1301	dicarboxylic acid transport
KKOR_RS03935	COG3724	N-succinylarginine dihydrolase activity
KKOR_RS03940	COG1012	belongs to the aldehyde dehydrogenase family
KKOR_RS03950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KKOR_RS03955	COG3047	cAMP biosynthetic process
KKOR_RS03965	COG4181	ATPase activity
KKOR_RS03970	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KKOR_RS03980	COG0167	dihydroorotate dehydrogenase activity
KKOR_RS03985	COG0116	Belongs to the methyltransferase superfamily
KKOR_RS03985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KKOR_RS04005	COG1960	acyl-CoA dehydrogenase activity
KKOR_RS04010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KKOR_RS04020	COG0456	acetyltransferase
KKOR_RS04030	COG0668	transmembrane transport
KKOR_RS04035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KKOR_RS04040	COG0084	hydrolase, TatD family'
KKOR_RS04050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KKOR_RS04055	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KKOR_RS04085	COG2200	EAL domain
KKOR_RS04090	COG2918	glutathione biosynthetic process
KKOR_RS04105	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KKOR_RS04115	COG0589	response to stress
KKOR_RS04125	COG4536	flavin adenine dinucleotide binding
KKOR_RS04135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KKOR_RS04150	COG0228	four-way junction DNA binding
KKOR_RS04160	COG0336	Belongs to the RNA methyltransferase TrmD family
KKOR_RS04165	COG0335	large ribosomal subunit rRNA binding
KKOR_RS04170	COG4974	Belongs to the 'phage' integrase family
KKOR_RS04185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KKOR_RS04195	COG0668	transmembrane transport
KKOR_RS04200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KKOR_RS04205	COG2205	protein histidine kinase activity
KKOR_RS04205	COG5002	protein histidine kinase activity
KKOR_RS04205	COG0784	Response regulator, receiver
KKOR_RS04220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKOR_RS04235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKOR_RS04240	COG3956	TIGRFAM MazG family protein
KKOR_RS04250	COG1671	Belongs to the UPF0178 family
KKOR_RS04260	COG0504	CTP synthase activity
KKOR_RS04265	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KKOR_RS04275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KKOR_RS04285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KKOR_RS04300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KKOR_RS04305	COG0107	imidazoleglycerol-phosphate synthase activity
KKOR_RS04310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KKOR_RS04315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KKOR_RS04320	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KKOR_RS04325	COG0585	pseudouridine synthase activity
KKOR_RS04330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KKOR_RS04335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KKOR_RS04340	COG1238	metal cluster binding
KKOR_RS04345	COG1388	LysM domain
KKOR_RS04345	COG4942	peptidase
KKOR_RS04360	COG2350	Protein conserved in bacteria
KKOR_RS04370	COG0613	PHP domain protein
KKOR_RS04375	COG0009	L-threonylcarbamoyladenylate synthase
KKOR_RS04390	COG5507	3-demethylubiquinone-9 3-methyltransferase
KKOR_RS04405	COG0180	Tryptophanyl-tRNA synthetase
KKOR_RS04415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KKOR_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
KKOR_RS04445	COG0745	RESPONSE REGULATOR receiver
KKOR_RS04470	COG0402	S-adenosylhomocysteine deaminase activity
KKOR_RS04480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KKOR_RS04485	COG1770	oligopeptidase
KKOR_RS04490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KKOR_RS04495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KKOR_RS04500	COG0539	negative regulation of cytoplasmic translation
KKOR_RS04515	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KKOR_RS04525	COG1555	photosystem II stabilization
KKOR_RS04530	COG0705	Rhomboid family
KKOR_RS04530	COG0457	Tetratricopeptide repeat
KKOR_RS04545	COG0659	secondary active sulfate transmembrane transporter activity
KKOR_RS04550	COG0589	response to stress
KKOR_RS04560	COG0436	Aminotransferase
KKOR_RS04565	COG0556	nucleotide-excision repair
KKOR_RS04600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKOR_RS04605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KKOR_RS04610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KKOR_RS04615	COG0110	maltose O-acetyltransferase activity
KKOR_RS04650	COG0438	transferase activity, transferring glycosyl groups
KKOR_RS04675	COG0175	sulfate reduction
KKOR_RS04685	COG0471	metal ion transport
KKOR_RS04685	COG3273	potassium ion transport
KKOR_RS04690	COG0529	Catalyzes the synthesis of activated sulfate
KKOR_RS04700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KKOR_RS04705	COG4660	Part of a membrane complex involved in electron transport
KKOR_RS04710	COG4659	FMN binding
KKOR_RS04715	COG4658	electron transport chain
KKOR_RS04720	COG4656	Part of a membrane complex involved in electron transport
KKOR_RS04725	COG2878	Part of a membrane complex involved in electron transport
KKOR_RS04730	COG4657	Part of a membrane complex involved in electron transport
KKOR_RS04740	COG2197	response regulator
KKOR_RS04745	COG0322	excinuclease ABC activity
KKOR_RS04775	COG0708	Exodeoxyribonuclease III
KKOR_RS04790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KKOR_RS04795	COG2062	phosphohistidine phosphatase, SixA
KKOR_RS04805	COG2890	protein-(glutamine-N5) methyltransferase activity
KKOR_RS04810	COG3101	peptidyl-lysine hydroxylation
KKOR_RS04820	COG2249	NAD(P)H dehydrogenase (quinone) activity
KKOR_RS04825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KKOR_RS04825	COG0475	glutathione-regulated potassium exporter activity
KKOR_RS04830	COG0390	transport system, permease component
KKOR_RS04850	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KKOR_RS04850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KKOR_RS04855	COG0302	gtp cyclohydrolase
KKOR_RS04860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KKOR_RS04875	COG0513	Belongs to the DEAD box helicase family
KKOR_RS04880	COG3530	Putative quorum-sensing-regulated virulence factor
KKOR_RS04900	COG0583	DNA-binding transcription factor activity
KKOR_RS04905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KKOR_RS04910	COG0066	3-isopropylmalate dehydratase activity
KKOR_RS04915	COG0473	3-isopropylmalate dehydrogenase activity
KKOR_RS04920	COG4133	protoheme IX ABC transporter activity
KKOR_RS04925	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KKOR_RS04940	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KKOR_RS04950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KKOR_RS04970	COG3220	belongs to the UPF0276 family
KKOR_RS04980	COG2853	Lipoprotein
KKOR_RS04995	COG1090	epimerase
KKOR_RS05000	COG1760	l-serine dehydratase
KKOR_RS05005	COG0494	nUDIX hydrolase
KKOR_RS05010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KKOR_RS05015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KKOR_RS05015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KKOR_RS05020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KKOR_RS05030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KKOR_RS05065	COG2132	Multicopper oxidase
KKOR_RS05070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KKOR_RS05075	COG2079	MmgE PrpD family protein
KKOR_RS05090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KKOR_RS05125	COG0189	ligase activity
KKOR_RS05125	COG4067	protein conserved in archaea
KKOR_RS05130	COG0189	ligase activity
KKOR_RS05145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KKOR_RS05150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KKOR_RS05170	COG0326	Molecular chaperone. Has ATPase activity
KKOR_RS05220	COG0563	adenylate kinase activity
KKOR_RS05225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KKOR_RS05230	COG1199	ATP-dependent helicase activity
KKOR_RS05235	COG1214	PFAM Peptidase M22, glycoprotease
KKOR_RS05245	COG0534	Mate efflux family protein
KKOR_RS05250	COG2850	peptidyl-arginine hydroxylation
KKOR_RS05255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KKOR_RS05275	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KKOR_RS05290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KKOR_RS05295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KKOR_RS05305	COG4770	biotin carboxylase activity
KKOR_RS05310	COG1024	Enoyl-CoA hydratase
KKOR_RS05315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KKOR_RS05320	COG1960	acyl-CoA dehydrogenase activity
KKOR_RS05325	COG0183	Belongs to the thiolase family
KKOR_RS05330	COG1960	acyl-CoA dehydrogenase activity
KKOR_RS05340	COG3130	regulation of translation
KKOR_RS05350	COG2373	Large extracellular alpha-helical protein
KKOR_RS05355	COG4953	penicillin-binding protein 1C
KKOR_RS05360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KKOR_RS05365	COG0343	queuine tRNA-ribosyltransferase activity
KKOR_RS05370	COG1862	Preprotein translocase
KKOR_RS05375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KKOR_RS05380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KKOR_RS05385	COG0668	transmembrane transport
KKOR_RS05395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KKOR_RS05400	COG1611	Belongs to the LOG family
KKOR_RS05420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KKOR_RS05420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KKOR_RS05425	COG0347	Belongs to the P(II) protein family
KKOR_RS05435	COG0564	pseudouridine synthase activity
KKOR_RS05440	COG1496	oxidoreductase activity
KKOR_RS05450	COG0542	response to heat
KKOR_RS05485	COG1183	phosphatidylcholine synthase activity
KKOR_RS05535	COG0482	sulfurtransferase activity
KKOR_RS05545	COG1187	pseudouridine synthase activity
KKOR_RS05555	COG4771	TonB-dependent receptor
KKOR_RS05575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKOR_RS05580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KKOR_RS05590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KKOR_RS05605	COG0492	ferredoxin-NADP+ reductase activity
KKOR_RS05615	COG1278	Cold shock
KKOR_RS05630	COG0686	Belongs to the AlaDH PNT family
KKOR_RS05640	COG1674	ftsk spoiiie
KKOR_RS05645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KKOR_RS05650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KKOR_RS05655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKOR_RS05660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KKOR_RS05690	COG1166	arginine decarboxylase activity
KKOR_RS05700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KKOR_RS05720	COG1012	belongs to the aldehyde dehydrogenase family
KKOR_RS05745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KKOR_RS05760	COG3706	GGDEF domain
KKOR_RS05765	COG3263	regulation of cellular component size
KKOR_RS05780	COG3139	Protein of unknown function (DUF1315)
KKOR_RS05790	COG0252	asparaginase activity
KKOR_RS05810	COG4771	TonB-dependent receptor
KKOR_RS05830	COG1473	amidohydrolase
KKOR_RS05835	COG1960	acyl-CoA dehydrogenase activity
KKOR_RS05845	COG1643	Atp-dependent helicase
KKOR_RS05850	COG3706	GGDEF domain
KKOR_RS05875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KKOR_RS05885	COG1530	ribonuclease E activity
KKOR_RS05895	COG0546	phosphoglycolate phosphatase activity
KKOR_RS05905	COG0726	polysaccharide deacetylase
KKOR_RS05905	COG1649	PFAM Uncharacterised BCR, COG1649
KKOR_RS05910	COG1215	transferase activity, transferring glycosyl groups
KKOR_RS05920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KKOR_RS05930	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KKOR_RS05935	COG3001	Fructosamine kinase
KKOR_RS05950	COG0424	maF-like protein
KKOR_RS05960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KKOR_RS05965	COG0416	fatty acid biosynthetic process
KKOR_RS05970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KKOR_RS05985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKOR_RS05990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KKOR_RS05995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KKOR_RS06000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KKOR_RS06005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KKOR_RS06020	COG0084	hydrolase, TatD family'
KKOR_RS06025	COG0612	Peptidase, M16
KKOR_RS06030	COG1404	Belongs to the peptidase S8 family
KKOR_RS06060	COG2197	response regulator
KKOR_RS06075	COG1960	acyl-CoA dehydrogenase activity
KKOR_RS06090	COG1196	nuclear chromosome segregation
KKOR_RS06090	COG3264	Mechanosensitive ion channel
KKOR_RS06140	COG0826	peptidase U32
KKOR_RS06150	COG0346	lactoylglutathione lyase activity
KKOR_RS06160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KKOR_RS06170	COG1741	Belongs to the pirin family
KKOR_RS06200	COG0384	phenazine biosynthesis protein PhzF
KKOR_RS06205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KKOR_RS06210	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KKOR_RS06220	COG1238	metal cluster binding
KKOR_RS06225	COG1228	amidohydrolase
KKOR_RS06230	COG2259	Doxx family
KKOR_RS06235	COG0583	DNA-binding transcription factor activity
KKOR_RS06250	COG1595	DNA-templated transcription, initiation
KKOR_RS06265	COG0511	ligase activity, forming carbon-carbon bonds
KKOR_RS06265	COG5016	pyruvate
KKOR_RS06270	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KKOR_RS06275	COG1228	amidohydrolase
KKOR_RS06455	COG0723	plastoquinol--plastocyanin reductase activity
KKOR_RS06465	COG5002	protein histidine kinase activity
KKOR_RS06485	COG2132	Multicopper oxidase
KKOR_RS06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KKOR_RS06515	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KKOR_RS06520	COG0789	Transcriptional regulator
KKOR_RS06525	COG2217	Heavy metal translocating P-type atpase
KKOR_RS06555	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KKOR_RS06560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKOR_RS06565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KKOR_RS06580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKOR_RS06645	COG0315	cyclic pyranopterin monophosphate synthase activity
KKOR_RS06650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KKOR_RS06655	COG0314	molybdopterin synthase activity
KKOR_RS06660	COG0746	molybdenum cofactor guanylyltransferase activity
KKOR_RS06665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KKOR_RS06680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KKOR_RS06685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KKOR_RS06690	COG2181	nitrate reductase activity
KKOR_RS06695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KKOR_RS06700	COG1140	nitrate reductase beta subunit
KKOR_RS06705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KKOR_RS06710	COG2223	nitrite transmembrane transporter activity
KKOR_RS06720	COG3850	Histidine kinase
KKOR_RS06725	COG2197	response regulator
KKOR_RS06730	COG0303	'Molybdopterin
KKOR_RS06735	COG0521	Mo-molybdopterin cofactor biosynthetic process
KKOR_RS06740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KKOR_RS06755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KKOR_RS06765	COG2217	Heavy metal translocating P-type atpase
KKOR_RS06780	COG0640	Transcriptional regulator
KKOR_RS06790	COG0798	PFAM Bile acid sodium symporter
KKOR_RS06805	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KKOR_RS06815	COG1283	sodium-dependent phosphate transmembrane transporter activity
KKOR_RS06820	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KKOR_RS06835	COG0018	arginyl-trna synthetase
KKOR_RS06840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKOR_RS06845	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KKOR_RS06850	COG2835	tetraacyldisaccharide 4'-kinase activity
KKOR_RS06855	COG1663	tetraacyldisaccharide 4'-kinase activity
KKOR_RS06865	COG0848	biopolymer transport protein
KKOR_RS06870	COG0811	peptide transport
KKOR_RS06890	COG0658	competence protein
KKOR_RS06890	COG2333	competence protein COMEC
KKOR_RS06900	COG1136	(ABC) transporter
KKOR_RS06920	COG1472	Belongs to the glycosyl hydrolase 3 family
KKOR_RS06930	COG3706	GGDEF domain
KKOR_RS06935	COG1272	protein, Hemolysin III
KKOR_RS06945	COG0446	pyridine nucleotide-disulphide oxidoreductase
KKOR_RS06945	COG1902	pentaerythritol trinitrate reductase activity
KKOR_RS06950	COG0616	signal peptide processing
KKOR_RS06965	COG2983	Belongs to the UPF0260 family
KKOR_RS06970	COG3100	YcgL domain-containing protein
KKOR_RS06975	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KKOR_RS06980	COG0318	PFAM AMP-dependent synthetase and ligase
KKOR_RS06990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKOR_RS07000	COG1757	Na H antiporter
KKOR_RS07005	COG0402	S-adenosylhomocysteine deaminase activity
KKOR_RS07010	COG1228	amidohydrolase
KKOR_RS07015	COG0733	neurotransmitter:sodium symporter activity
KKOR_RS07025	COG1960	acyl-CoA dehydrogenase activity
KKOR_RS07030	COG1115	amino acid carrier protein
KKOR_RS07035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKOR_RS07070	COG1022	Amp-dependent synthetase and ligase
KKOR_RS07090	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KKOR_RS07095	COG2988	succinylglutamate desuccinylase activity
KKOR_RS07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KKOR_RS07140	COG1136	(ABC) transporter
KKOR_RS07180	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KKOR_RS07185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KKOR_RS07190	COG2137	regulation of response to DNA damage stimulus
KKOR_RS07195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KKOR_RS07200	COG1546	Belongs to the CinA family
KKOR_RS07210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KKOR_RS07215	COG0402	S-adenosylhomocysteine deaminase activity
KKOR_RS07235	COG0446	pyridine nucleotide-disulphide oxidoreductase
KKOR_RS07240	COG0626	cystathionine gamma-synthase activity
KKOR_RS07245	COG1522	sequence-specific DNA binding
KKOR_RS07265	COG4106	trans-aconitate 2-methyltransferase activity
KKOR_RS07270	COG0500	methyltransferase
KKOR_RS07275	COG0564	pseudouridine synthase activity
KKOR_RS07305	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KKOR_RS07310	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KKOR_RS07315	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KKOR_RS07320	COG0542	response to heat
KKOR_RS07325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KKOR_RS07335	COG2062	phosphohistidine phosphatase, SixA
KKOR_RS07345	COG3422	double-strand break repair
KKOR_RS07350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KKOR_RS07355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKOR_RS07360	COG0308	aminopeptidase N
KKOR_RS07365	COG4242	Belongs to the peptidase S51 family
KKOR_RS07385	COG0277	FAD linked oxidase domain protein
KKOR_RS07395	COG0745	RESPONSE REGULATOR receiver
KKOR_RS07395	COG3292	Two component regulator propeller
KKOR_RS07395	COG2205	protein histidine kinase activity
KKOR_RS07400	COG0204	Acyl-transferase
KKOR_RS07410	COG1286	toxin biosynthetic process
KKOR_RS07420	COG0285	dihydrofolate synthase activity
KKOR_RS07425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KKOR_RS07430	COG0101	tRNA pseudouridine synthase activity
KKOR_RS07440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KKOR_RS07450	COG0308	aminopeptidase N
KKOR_RS07480	COG1505	serine-type exopeptidase activity
KKOR_RS07485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KKOR_RS07495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KKOR_RS07500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KKOR_RS07550	COG1104	cysteine desulfurase activity
KKOR_RS07565	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KKOR_RS07600	COG0625	glutathione transferase activity
KKOR_RS07610	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KKOR_RS07625	COG0741	lytic transglycosylase activity
KKOR_RS07640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KKOR_RS07660	COG1228	amidohydrolase
KKOR_RS07665	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KKOR_RS07675	COG2188	Transcriptional regulator
KKOR_RS07680	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KKOR_RS07685	COG2986	histidine ammonia-lyase
KKOR_RS07705	COG0612	Peptidase, M16
KKOR_RS07715	COG0045	succinate-CoA ligase (ADP-forming) activity
KKOR_RS07720	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKOR_RS07725	COG0567	Dehydrogenase, E1 component
KKOR_RS07730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KKOR_RS07735	COG1053	succinate dehydrogenase
KKOR_RS07740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KKOR_RS07750	COG0372	Belongs to the citrate synthase family
KKOR_RS07765	COG1956	GAF domain-containing protein
KKOR_RS07775	COG0017	Asparaginyl-tRNA synthetase
KKOR_RS07780	COG0778	Nitroreductase
KKOR_RS07805	COG0823	Involved in the tonB-independent uptake of proteins
KKOR_RS07805	COG1506	peptidase
KKOR_RS07830	COG2030	dehydratase
KKOR_RS07835	COG2301	Belongs to the HpcH HpaI aldolase family
KKOR_RS07840	COG0318	PFAM AMP-dependent synthetase and ligase
KKOR_RS07855	COG1132	(ABC) transporter
KKOR_RS07900	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KKOR_RS07905	COG2923	Belongs to the DsrF TusC family
KKOR_RS07915	COG2920	part of a sulfur-relay system
KKOR_RS07925	COG0678	peroxiredoxin activity
KKOR_RS07930	COG0405	Gamma-glutamyltransferase
KKOR_RS07940	COG0077	Prephenate dehydratase
KKOR_RS07940	COG1605	Chorismate mutase
KKOR_RS07945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KKOR_RS07955	COG1054	Belongs to the UPF0176 family
KKOR_RS07975	COG0791	NLP P60 protein
KKOR_RS08015	COG2824	Alkylphosphonate utilization operon protein PhnA
KKOR_RS08040	COG2096	Adenosyltransferase
KKOR_RS08045	COG4206	TonB-dependent receptor
KKOR_RS08070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KKOR_RS08080	COG0527	aspartate kinase activity
KKOR_RS08080	COG0460	homoserine dehydrogenase
KKOR_RS08085	COG0626	cystathionine gamma-synthase activity
KKOR_RS08090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KKOR_RS08095	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
KKOR_RS08105	COG0583	DNA-binding transcription factor activity
KKOR_RS08115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KKOR_RS08120	COG1505	serine-type exopeptidase activity
KKOR_RS08130	COG2866	Carboxypeptidase
KKOR_RS08140	COG0745	RESPONSE REGULATOR receiver
KKOR_RS08145	COG2205	protein histidine kinase activity
KKOR_RS08150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KKOR_RS08155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KKOR_RS08160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KKOR_RS08165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KKOR_RS08170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KKOR_RS08185	COG4783	chaperone-mediated protein folding
KKOR_RS08190	COG3118	belongs to the thioredoxin family
KKOR_RS08200	COG1295	ribonuclease BN
KKOR_RS08205	COG1393	Belongs to the ArsC family
KKOR_RS08220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KKOR_RS08225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KKOR_RS08235	COG0159	tryptophan synthase activity
KKOR_RS08240	COG0133	tryptophan synthase activity
KKOR_RS08245	COG0135	phosphoribosylanthranilate isomerase activity
KKOR_RS08245	COG0134	indole-3-glycerol-phosphate synthase activity
KKOR_RS08250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KKOR_RS08255	COG0512	Glutamine amidotransferase of anthranilate synthase
KKOR_RS08255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KKOR_RS08260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KKOR_RS08265	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KKOR_RS08285	COG4966	pilus assembly protein PilW
KKOR_RS08330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KKOR_RS08335	COG1047	Peptidyl-prolyl cis-trans
KKOR_RS08340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KKOR_RS08345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KKOR_RS08350	COG0196	riboflavin kinase activity
KKOR_RS08360	COG0728	peptidoglycan biosynthetic process
KKOR_RS08365	COG0268	Binds directly to 16S ribosomal RNA
KKOR_RS08385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KKOR_RS08395	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KKOR_RS08400	COG0142	geranyltranstransferase activity
KKOR_RS08405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KKOR_RS08410	COG5001	Diguanylate cyclase
KKOR_RS08410	COG5002	protein histidine kinase activity
KKOR_RS08430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KKOR_RS08435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKOR_RS08450	COG2885	chlorophyll binding
KKOR_RS08450	COG3047	cAMP biosynthetic process
KKOR_RS08455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KKOR_RS08460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KKOR_RS08475	COG0717	Belongs to the dCTP deaminase family
KKOR_RS08480	COG0489	protein tyrosine kinase activity
KKOR_RS08485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KKOR_RS08485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KKOR_RS08510	COG0405	Gamma-glutamyltransferase
KKOR_RS08515	COG1605	Chorismate mutase
KKOR_RS08515	COG0077	Prephenate dehydratase
KKOR_RS08520	COG0826	peptidase U32
KKOR_RS08525	COG0826	peptidase U32
KKOR_RS08530	COG3154	lipid carrier protein
KKOR_RS08580	COG0776	regulation of translation
KKOR_RS08585	COG0072	phenylalanine-tRNA ligase activity
KKOR_RS08590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KKOR_RS08595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KKOR_RS08600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KKOR_RS08605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KKOR_RS08610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKOR_RS08630	COG1741	Belongs to the pirin family
KKOR_RS08640	COG3920	Histidine kinase
KKOR_RS08640	COG2202	Pas domain
KKOR_RS08650	COG1294	oxidase, subunit
KKOR_RS08655	COG1271	oxidase subunit
KKOR_RS08665	COG4771	TonB-dependent receptor
KKOR_RS08685	COG0418	dihydroorotase activity
KKOR_RS08690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KKOR_RS08700	COG1446	asparaginase
KKOR_RS08715	COG0450	alkyl hydroperoxide reductase
KKOR_RS08740	COG0584	glycerophosphoryl diester phosphodiesterase
KKOR_RS08750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KKOR_RS08755	COG3842	ATPase activity
KKOR_RS08760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKOR_RS08760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKOR_RS08765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKOR_RS08810	COG5001	Diguanylate cyclase
KKOR_RS08810	COG3300	MHYT domain
KKOR_RS08835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KKOR_RS08845	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KKOR_RS08855	COG0626	cystathionine gamma-synthase activity
KKOR_RS08865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KKOR_RS08870	COG0022	dehydrogenase e1 component
KKOR_RS08875	COG1404	Belongs to the peptidase S8 family
KKOR_RS08880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KKOR_RS08885	COG3228	Belongs to the MtfA family
KKOR_RS08895	COG2081	HI0933 family
KKOR_RS08900	COG0697	spore germination
KKOR_RS08925	COG2900	Belongs to the SlyX family
KKOR_RS08930	COG1129	ABC transporter
KKOR_RS08930	COG0842	Transport permease protein
KKOR_RS08935	COG1131	(ABC) transporter
KKOR_RS08940	COG3012	SEC-C Motif Domain Protein
KKOR_RS08950	COG1575	Belongs to the MenA family. Type 1 subfamily
KKOR_RS08965	COG2974	May be involved in recombination
KKOR_RS08970	COG0545	Peptidyl-prolyl cis-trans isomerase
KKOR_RS09055	COG2885	chlorophyll binding
KKOR_RS09060	COG2199	diguanylate cyclase activity
KKOR_RS09065	COG2989	Protein conserved in bacteria
KKOR_RS09080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KKOR_RS09110	COG1073	alpha beta
KKOR_RS09135	COG2264	protein methyltransferase activity
KKOR_RS09140	COG0795	lipopolysaccharide-transporting ATPase activity
KKOR_RS09145	COG0795	lipopolysaccharide-transporting ATPase activity
KKOR_RS09150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KKOR_RS09165	COG0525	valine-tRNA ligase activity
KKOR_RS09180	COG0527	aspartate kinase activity
KKOR_RS09195	COG0516	GMP reductase activity
KKOR_RS09195	COG0517	IMP dehydrogenase activity
KKOR_RS09200	COG1570	exodeoxyribonuclease VII activity
KKOR_RS09210	COG1160	GTP binding
KKOR_RS09215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KKOR_RS09220	COG2976	Protein conserved in bacteria
KKOR_RS09230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KKOR_RS09235	COG1426	Protein conserved in bacteria
KKOR_RS09260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KKOR_RS09265	COG0602	queuosine metabolic process
KKOR_RS09275	COG2885	chlorophyll binding
KKOR_RS09280	COG0823	Involved in the tonB-independent uptake of proteins
KKOR_RS09295	COG0811	peptide transport
KKOR_RS09300	COG0824	Thioesterase
KKOR_RS09310	COG0488	(ABC) transporter
KKOR_RS09350	COG5002	protein histidine kinase activity
KKOR_RS09350	COG5001	Diguanylate cyclase
KKOR_RS09350	COG3447	MASE1 domain protein
KKOR_RS09355	COG0632	four-way junction helicase activity
KKOR_RS09365	COG0217	transcriptional regulatory protein
KKOR_RS09370	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KKOR_RS09385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KKOR_RS09390	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KKOR_RS09400	COG0442	prolyl-tRNA aminoacylation
KKOR_RS09405	COG0741	lytic transglycosylase activity
KKOR_RS09425	COG0037	tRNA processing
KKOR_RS09430	COG0825	malonyl-CoA metabolic process
KKOR_RS09440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KKOR_RS09465	COG0693	protein deglycase activity
KKOR_RS09485	COG1228	amidohydrolase
KKOR_RS09495	COG2130	NADP-dependent
KKOR_RS09530	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KKOR_RS09535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KKOR_RS09540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KKOR_RS09545	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KKOR_RS09555	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KKOR_RS09565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KKOR_RS09570	COG0575	Belongs to the CDS family
KKOR_RS09580	COG0233	cytoplasmic translational termination
KKOR_RS09585	COG0528	UMP kinase activity
KKOR_RS09595	COG0052	Belongs to the universal ribosomal protein uS2 family
KKOR_RS09630	COG5507	3-demethylubiquinone-9 3-methyltransferase
KKOR_RS09635	COG0024	Methionine aminopeptidase
KKOR_RS09645	COG2171	N-acyltransferase activity
KKOR_RS09650	COG1393	Belongs to the ArsC family
KKOR_RS09660	COG1876	peptidase activity
KKOR_RS09670	COG0471	metal ion transport
KKOR_RS09675	COG1024	Enoyl-CoA hydratase
KKOR_RS09695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKOR_RS09700	COG1388	LysM domain
KKOR_RS09700	COG0741	lytic transglycosylase activity
KKOR_RS09705	COG1668	transmembrane transport
KKOR_RS09710	COG4555	ABC transporter
KKOR_RS09715	COG3768	UPF0283 membrane protein
KKOR_RS09720	COG3106	COG3106 Predicted ATPase
KKOR_RS09740	COG0848	biopolymer transport protein
KKOR_RS09745	COG0811	peptide transport
KKOR_RS09750	COG0811	peptide transport
KKOR_RS09765	COG0747	negative chemotaxis
KKOR_RS09770	COG0601	transmembrane transport
KKOR_RS09775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKOR_RS09780	COG0444	Belongs to the ABC transporter superfamily
KKOR_RS09785	COG4608	Belongs to the ABC transporter superfamily
KKOR_RS09790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KKOR_RS09805	COG0776	regulation of translation
KKOR_RS09810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KKOR_RS09815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KKOR_RS09830	COG0740	serine-type endopeptidase activity
KKOR_RS09835	COG0544	peptidyl-prolyl cis-trans isomerase activity
KKOR_RS09860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKOR_RS09870	COG0204	Acyl-transferase
KKOR_RS09875	COG4589	Belongs to the CDS family
KKOR_RS09880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKOR_RS09890	COG0215	cysteine-tRNA ligase activity
KKOR_RS09895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KKOR_RS09900	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KKOR_RS09915	COG3340	Belongs to the peptidase S51 family
KKOR_RS09935	COG0714	Associated with various cellular activities
KKOR_RS09950	COG1024	Enoyl-CoA hydratase
KKOR_RS09950	COG1250	3-hydroxyacyl-CoA dehydrogenase
KKOR_RS09955	COG0183	Belongs to the thiolase family
KKOR_RS09960	COG0714	Associated with various cellular activities
KKOR_RS10000	COG2902	Dehydrogenase
KKOR_RS10010	COG4447	cellulose binding
KKOR_RS10035	COG1131	(ABC) transporter
KKOR_RS10040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KKOR_RS10045	COG2855	membrane
KKOR_RS10060	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KKOR_RS10065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKOR_RS10070	COG1509	lysine 2,3-aminomutase activity
KKOR_RS10115	COG0494	nUDIX hydrolase
KKOR_RS10125	COG1538	Outer membrane efflux protein
KKOR_RS10130	COG1519	Transferase
KKOR_RS10140	COG2867	negative regulation of translational initiation
KKOR_RS10145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KKOR_RS10155	COG2815	serine threonine protein kinase
KKOR_RS10155	COG0515	serine threonine protein kinase
KKOR_RS10210	COG1136	(ABC) transporter
KKOR_RS10210	COG0577	efflux transmembrane transporter activity
KKOR_RS10220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KKOR_RS10225	COG1309	transcriptional regulator
KKOR_RS10230	COG1959	2 iron, 2 sulfur cluster binding
KKOR_RS10235	COG2832	Protein of unknown function (DUF454)
KKOR_RS10250	COG3256	nitric oxide reductase
KKOR_RS10275	COG4264	IucA IucC family
KKOR_RS10315	COG0540	Belongs to the ATCase OTCase family
KKOR_RS10335	COG1595	DNA-templated transcription, initiation
KKOR_RS10365	COG0071	Belongs to the small heat shock protein (HSP20) family
KKOR_RS10375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KKOR_RS10385	COG2814	Major facilitator Superfamily
KKOR_RS10390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKOR_RS10420	COG4946	Tricorn protease homolog
KKOR_RS10420	COG1506	peptidase
KKOR_RS10420	COG0823	Involved in the tonB-independent uptake of proteins
KKOR_RS10435	COG4221	oxidoreductase activity
KKOR_RS10440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KKOR_RS10445	COG0583	DNA-binding transcription factor activity
KKOR_RS10460	COG0402	S-adenosylhomocysteine deaminase activity
KKOR_RS10475	COG1970	mechanosensitive ion channel activity
KKOR_RS10480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KKOR_RS10500	COG4771	TonB-dependent receptor
KKOR_RS10505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KKOR_RS10530	COG0704	Plays a role in the regulation of phosphate uptake
KKOR_RS10535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KKOR_RS10540	COG0573	inorganic phosphate transmembrane transporter activity
KKOR_RS10545	COG0573	inorganic phosphate transmembrane transporter activity
KKOR_RS10585	COG0793	Belongs to the peptidase S41A family
KKOR_RS10595	COG5002	protein histidine kinase activity
KKOR_RS10595	COG5000	phosphorelay sensor kinase activity
KKOR_RS10605	COG0670	Belongs to the BI1 family
KKOR_RS10615	COG2814	Major facilitator Superfamily
KKOR_RS10620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KKOR_RS10625	COG1253	flavin adenine dinucleotide binding
KKOR_RS10635	COG0488	(ABC) transporter
KKOR_RS10660	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KKOR_RS10675	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KKOR_RS10685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KKOR_RS10695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KKOR_RS10705	COG2226	methyltransferase
KKOR_RS10710	COG0596	Alpha beta hydrolase
KKOR_RS10715	COG0156	8-amino-7-oxononanoate synthase activity
KKOR_RS10720	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KKOR_RS10725	COG1040	competence protein
KKOR_RS10740	COG0534	Mate efflux family protein
KKOR_RS10745	COG0456	acetyltransferase
KKOR_RS10765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KKOR_RS10765	COG0316	Belongs to the HesB IscA family
KKOR_RS10770	COG0527	aspartate kinase activity
KKOR_RS10780	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KKOR_RS10785	COG1704	LemA family
KKOR_RS10790	COG0501	Belongs to the peptidase M48B family
KKOR_RS10810	COG1392	Phosphate transport regulator
KKOR_RS10815	COG0306	phosphate transporter
KKOR_RS10835	COG0612	Peptidase, M16
KKOR_RS10845	COG3267	Type II secretory pathway component ExeA
KKOR_RS10845	COG3409	Peptidoglycan-binding domain 1 protein
KKOR_RS10855	COG0617	tRNA 3'-terminal CCA addition
KKOR_RS10860	COG1968	undecaprenyl-diphosphatase activity
KKOR_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
KKOR_RS10880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KKOR_RS10885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KKOR_RS10890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KKOR_RS10900	COG2814	Major facilitator Superfamily
KKOR_RS10920	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KKOR_RS10955	COG4572	Cation transport regulator
KKOR_RS10975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KKOR_RS10980	COG5001	Diguanylate cyclase
KKOR_RS11000	COG2020	methyltransferase activity
KKOR_RS11015	COG2207	Transcriptional regulator
KKOR_RS11045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KKOR_RS11075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KKOR_RS11080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KKOR_RS11100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KKOR_RS11105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KKOR_RS11115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KKOR_RS11120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KKOR_RS11125	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KKOR_RS11130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KKOR_RS11150	COG1309	transcriptional regulator
KKOR_RS11160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KKOR_RS11165	COG2003	Belongs to the UPF0758 family
KKOR_RS11170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KKOR_RS11175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KKOR_RS11180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KKOR_RS11185	COG0848	biopolymer transport protein
KKOR_RS11200	COG0727	PFAM Uncharacterised protein family (UPF0153)
KKOR_RS11210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KKOR_RS11215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KKOR_RS11235	COG0429	hydrolase of the alpha beta-hydrolase fold
KKOR_RS11250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KKOR_RS11255	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KKOR_RS11290	COG0254	rRNA binding
KKOR_RS11320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KKOR_RS11325	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KKOR_RS11330	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KKOR_RS11335	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KKOR_RS11340	COG1404	Belongs to the peptidase S8 family
KKOR_RS11350	COG2226	methyltransferase
KKOR_RS11360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KKOR_RS11370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKOR_RS11375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKOR_RS11380	COG0805	protein transport
KKOR_RS11405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KKOR_RS11410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KKOR_RS11420	COG0628	permease
KKOR_RS11430	COG0477	Major facilitator Superfamily
KKOR_RS11440	COG1490	D-aminoacyl-tRNA deacylase activity
KKOR_RS11450	COG1217	gtp-binding protein TYPA
KKOR_RS11455	COG3706	GGDEF domain
KKOR_RS11465	COG0482	sulfurtransferase activity
KKOR_RS11485	COG0457	Tetratricopeptide repeat
KKOR_RS11495	COG0174	glutamine synthetase
KKOR_RS11505	COG3852	Histidine kinase
KKOR_RS11510	COG2204	response regulator
KKOR_RS11510	COG2204	response regulator
KKOR_RS11515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KKOR_RS11520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KKOR_RS11525	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KKOR_RS11535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKOR_RS11545	COG0330	HflC and HflK could
KKOR_RS11550	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KKOR_RS11555	COG4942	peptidase
KKOR_RS11560	COG0793	Belongs to the peptidase S41A family
KKOR_RS11575	COG0494	nUDIX hydrolase
KKOR_RS11580	COG1011	Hydrolase
KKOR_RS11590	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KKOR_RS11595	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KKOR_RS11605	COG4795	General secretion pathway protein
KKOR_RS11615	COG2165	general secretion pathway protein
KKOR_RS11620	COG2165	general secretion pathway protein
KKOR_RS11625	COG1459	type II secretion system
KKOR_RS11645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KKOR_RS11650	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KKOR_RS11665	COG2183	response to ionizing radiation
KKOR_RS11670	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KKOR_RS11685	COG0545	Peptidyl-prolyl cis-trans isomerase
KKOR_RS11695	COG2363	Small membrane protein
KKOR_RS11700	COG1560	Kdo2-lipid A biosynthetic process
KKOR_RS11705	COG0534	Mate efflux family protein
KKOR_RS11715	COG0109	protoheme IX farnesyltransferase activity
KKOR_RS11720	COG1612	heme a metabolic process
KKOR_RS11745	COG3642	lipopolysaccharide core region biosynthetic process
KKOR_RS11750	COG0859	PFAM glycosyl transferase family 9
KKOR_RS11785	COG1982	Orn Lys Arg decarboxylase major
KKOR_RS11800	COG2226	methyltransferase
KKOR_RS11820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KKOR_RS11825	COG0149	triose-phosphate isomerase activity
KKOR_RS11830	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KKOR_RS11835	COG1805	sodium ion transport
KKOR_RS11840	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KKOR_RS11850	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KKOR_RS11855	COG2871	sodium ion transport
KKOR_RS11860	COG1477	protein flavinylation
KKOR_RS11875	COG4109	DRTGG domain
KKOR_RS11885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKOR_RS11890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KKOR_RS11900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KKOR_RS11905	COG1534	Rna-binding protein
KKOR_RS11910	COG0745	RESPONSE REGULATOR receiver
KKOR_RS11915	COG5002	protein histidine kinase activity
KKOR_RS11920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KKOR_RS11935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KKOR_RS11965	COG0415	Belongs to the DNA photolyase family
KKOR_RS11970	COG3272	Protein of unknown function (DUF1722)
KKOR_RS11990	COG0505	Belongs to the CarA family
KKOR_RS11995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KKOR_RS12000	COG2755	lipolytic protein G-D-S-L family
KKOR_RS12005	COG1297	OPT oligopeptide transporter protein
KKOR_RS12010	COG0583	DNA-binding transcription factor activity
KKOR_RS12020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KKOR_RS12025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KKOR_RS12030	COG0484	heat shock protein binding
KKOR_RS12035	COG0443	Heat shock 70 kDa protein
KKOR_RS12050	COG0217	transcriptional regulatory protein
KKOR_RS12085	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KKOR_RS12090	COG1420	regulation of RNA biosynthetic process
KKOR_RS12095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKOR_RS12100	COG0497	DNA recombination
KKOR_RS12110	COG0730	response to heat
KKOR_RS12115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KKOR_RS12120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKOR_RS12150	COG0039	L-malate dehydrogenase activity
KKOR_RS12160	COG0583	DNA-binding transcription factor activity
KKOR_RS12170	COG2311	Membrane
KKOR_RS12175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKOR_RS12185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKOR_RS12190	COG1758	RNA polymerase activity
KKOR_RS12200	COG1561	YicC-like family, N-terminal region
KKOR_RS12205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KKOR_RS12210	COG2967	ApaG domain
KKOR_RS12215	COG4221	oxidoreductase activity
KKOR_RS12230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KKOR_RS12255	COG0281	malic enzyme
KKOR_RS12265	COG0069	glutamate synthase activity
KKOR_RS12270	COG1595	DNA-templated transcription, initiation
KKOR_RS12280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KKOR_RS12295	COG0494	nUDIX hydrolase
KKOR_RS12300	COG3066	DNA modification
KKOR_RS12325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKOR_RS12325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKOR_RS12330	COG0509	glycine decarboxylation via glycine cleavage system
KKOR_RS12345	COG1178	ABC-type Fe3 transport system permease component
KKOR_RS12365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKOR_RS12380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKOR_RS12385	COG0006	proline dipeptidase activity
KKOR_RS12405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KKOR_RS12415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KKOR_RS12430	COG2204	response regulator
KKOR_RS12445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KKOR_RS12455	COG0126	phosphoglycerate kinase activity
KKOR_RS12460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KKOR_RS12465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KKOR_RS12475	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KKOR_RS12480	COG1331	Highly conserved protein containing a thioredoxin domain
KKOR_RS12520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKOR_RS12520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKOR_RS12540	COG0631	protein serine/threonine phosphatase activity
KKOR_RS12575	COG2815	serine threonine protein kinase
KKOR_RS12575	COG0515	serine threonine protein kinase
KKOR_RS12580	COG3608	succinylglutamate desuccinylase aspartoacylase
KKOR_RS12585	COG1525	nuclease
KKOR_RS12600	COG4771	TonB-dependent receptor
KKOR_RS12615	COG0471	metal ion transport
KKOR_RS12615	COG3273	potassium ion transport
KKOR_RS12625	COG2050	protein possibly involved in aromatic compounds catabolism
KKOR_RS12640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KKOR_RS12705	COG1506	peptidase
KKOR_RS12705	COG4946	Tricorn protease homolog
KKOR_RS12705	COG0823	Involved in the tonB-independent uptake of proteins
KKOR_RS12715	COG0783	Belongs to the Dps family
KKOR_RS12720	COG0425	Belongs to the sulfur carrier protein TusA family
KKOR_RS12740	COG2818	Glycosylase
KKOR_RS12750	COG0751	glycine-tRNA ligase activity
KKOR_RS12770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KKOR_RS12775	COG5001	Diguanylate cyclase
KKOR_RS12775	COG3300	MHYT domain
KKOR_RS12795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KKOR_RS12810	COG0463	Glycosyl transferase, family 2
KKOR_RS12815	COG0339	signal peptide processing
KKOR_RS12820	COG1070	Carbohydrate kinase
KKOR_RS12855	COG1573	uracil-dna glycosylase
KKOR_RS12860	COG0564	pseudouridine synthase activity
KKOR_RS12865	COG0742	ribosomal rna small subunit methyltransferase
KKOR_RS12870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KKOR_RS12875	COG0742	ribosomal rna small subunit methyltransferase
KKOR_RS12880	COG0552	protein localization to endoplasmic reticulum
KKOR_RS12885	COG2884	Cell division ATP-binding protein ftsE
KKOR_RS12890	COG2177	Part of the ABC transporter FtsEX involved in
KKOR_RS12915	COG0204	Acyl-transferase
KKOR_RS12925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKOR_RS12945	COG1215	transferase activity, transferring glycosyl groups
KKOR_RS12950	COG2986	histidine ammonia-lyase
KKOR_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
KKOR_RS12995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KKOR_RS13005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KKOR_RS13025	COG0513	Belongs to the DEAD box helicase family
KKOR_RS13060	COG1247	-acetyltransferase
KKOR_RS13105	COG0408	coproporphyrinogen oxidase activity
KKOR_RS13110	COG0009	L-threonylcarbamoyladenylate synthase
KKOR_RS13115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KKOR_RS13120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KKOR_RS13125	COG2922	Belongs to the Smg family
KKOR_RS13130	COG0758	DNA mediated transformation
KKOR_RS13140	COG0242	peptide deformylase activity
KKOR_RS13150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKOR_RS13150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KKOR_RS13155	COG0569	domain protein
KKOR_RS13160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KKOR_RS13170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KKOR_RS13175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KKOR_RS13180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KKOR_RS13185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KKOR_RS13200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KKOR_RS13205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKOR_RS13210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KKOR_RS13230	COG1475	DNA binding
KKOR_RS13235	COG1192	Involved in chromosome partitioning
KKOR_RS13240	COG0357	Ribosomal RNA small subunit methyltransferase G
KKOR_RS13245	COG0445	tRNA wobble uridine modification
KKOR_RS13265	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KKOR_RS13270	COG0706	membrane insertase activity
KKOR_RS13275	COG0594	ribonuclease P activity
KKOR_RS13280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KKOR_RS13300	COG2203	Gaf domain
KKOR_RS13300	COG2199	diguanylate cyclase activity
KKOR_RS13325	COG2917	probably involved in intracellular septation
KKOR_RS13360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides