locus-tag	class	description
KvSKV_RS00005	COG0424	maF-like protein
KvSKV_RS00010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KvSKV_RS00015	COG0237	dephospho-CoA kinase activity
KvSKV_RS00020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KvSKV_RS00025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KvSKV_RS00050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KvSKV_RS00055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KvSKV_RS00070	COG1074	ATP-dependent DNA helicase activity
KvSKV_RS00075	COG2887	Belongs to the helicase family. UvrD subfamily
KvSKV_RS00080	COG0802	atpase or kinase
KvSKV_RS00095	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KvSKV_RS00100	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KvSKV_RS00105	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KvSKV_RS00130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KvSKV_RS00135	COG1846	Transcriptional regulator
KvSKV_RS00140	COG0745	RESPONSE REGULATOR receiver
KvSKV_RS00150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KvSKV_RS00175	COG1674	ftsk spoiiie
KvSKV_RS00205	COG3842	ATPase activity
KvSKV_RS00220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KvSKV_RS00230	COG1609	Transcriptional regulator
KvSKV_RS00245	COG1194	a g-specific adenine glycosylase
KvSKV_RS00260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KvSKV_RS00270	COG1663	tetraacyldisaccharide 4'-kinase activity
KvSKV_RS00275	COG1519	Transferase
KvSKV_RS00290	COG2081	HI0933 family
KvSKV_RS00295	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KvSKV_RS00320	COG0495	leucyl-tRNA aminoacylation
KvSKV_RS00345	COG0745	RESPONSE REGULATOR receiver
KvSKV_RS00355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KvSKV_RS00375	COG2857	Cytochrome c1
KvSKV_RS00380	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KvSKV_RS00390	COG4143	(ABC) transporter
KvSKV_RS00395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KvSKV_RS00405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KvSKV_RS00410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KvSKV_RS00415	COG0564	pseudouridine synthase activity
KvSKV_RS00425	COG0443	Heat shock 70 kDa protein
KvSKV_RS00430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KvSKV_RS00435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KvSKV_RS00445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KvSKV_RS00455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KvSKV_RS00485	COG1054	Belongs to the UPF0176 family
KvSKV_RS00490	COG1335	isochorismatase
KvSKV_RS00495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KvSKV_RS00525	COG0514	ATP-dependent DNA helicase (RecQ)
KvSKV_RS00530	COG3022	response to hydroperoxide
KvSKV_RS00535	COG1132	(ABC) transporter
KvSKV_RS00545	COG0560	Phosphoserine phosphatase
KvSKV_RS00545	COG3830	Belongs to the UPF0237 family
KvSKV_RS00550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KvSKV_RS00555	COG0402	S-adenosylhomocysteine deaminase activity
KvSKV_RS00560	COG0702	epimerase
KvSKV_RS00565	COG1733	regulation of RNA biosynthetic process
KvSKV_RS00575	COG1253	flavin adenine dinucleotide binding
KvSKV_RS00595	COG3813	Protein conserved in bacteria
KvSKV_RS00600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KvSKV_RS00615	COG0284	orotidine-5'-phosphate decarboxylase activity
KvSKV_RS00625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KvSKV_RS00630	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KvSKV_RS00675	COG3754	Rhamnan synthesis protein F
KvSKV_RS00685	COG1132	(ABC) transporter
KvSKV_RS00695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KvSKV_RS00705	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KvSKV_RS00705	COG1082	Xylose isomerase domain protein TIM barrel
KvSKV_RS00715	COG1802	Transcriptional regulator
KvSKV_RS00720	COG1802	Transcriptional regulator
KvSKV_RS00725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KvSKV_RS00735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KvSKV_RS00740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KvSKV_RS00750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KvSKV_RS00755	COG0583	DNA-binding transcription factor activity
KvSKV_RS00765	COG1785	Belongs to the alkaline phosphatase family
KvSKV_RS00785	COG0714	Associated with various cellular activities
KvSKV_RS00800	COG0523	cobalamin synthesis protein
KvSKV_RS00830	COG1122	ATPase activity
KvSKV_RS00835	COG0390	transport system, permease component
KvSKV_RS00860	COG2072	flavoprotein involved in K transport
KvSKV_RS00885	COG4208	sulfate ABC transporter
KvSKV_RS00895	COG2897	thiosulfate sulfurtransferase activity
KvSKV_RS00900	COG2391	methyltransferase activity
KvSKV_RS00910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KvSKV_RS00925	COG1877	trehalose-phosphatase activity
KvSKV_RS00930	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KvSKV_RS00940	COG2151	metal-sulfur cluster biosynthetic enzyme
KvSKV_RS00940	COG0489	protein tyrosine kinase activity
KvSKV_RS00945	COG0513	Belongs to the DEAD box helicase family
KvSKV_RS00955	COG1742	UPF0060 membrane protein
KvSKV_RS00965	COG0335	large ribosomal subunit rRNA binding
KvSKV_RS00975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KvSKV_RS00980	COG0228	four-way junction DNA binding
KvSKV_RS01000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KvSKV_RS01010	COG0640	Transcriptional regulator
KvSKV_RS01020	COG0356	it plays a direct role in the translocation of protons across the membrane
KvSKV_RS01030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KvSKV_RS01035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KvSKV_RS01055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KvSKV_RS01065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KvSKV_RS01070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KvSKV_RS01075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KvSKV_RS01095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KvSKV_RS01125	COG0567	Dehydrogenase, E1 component
KvSKV_RS01135	COG0045	succinate-CoA ligase (ADP-forming) activity
KvSKV_RS01140	COG0039	L-malate dehydrogenase activity
KvSKV_RS01230	COG0747	negative chemotaxis
KvSKV_RS01235	COG0601	transmembrane transport
KvSKV_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS01250	COG1124	(ABC) transporter
KvSKV_RS01255	COG2188	Transcriptional regulator
KvSKV_RS01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS01285	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS01290	COG4608	Belongs to the ABC transporter superfamily
KvSKV_RS01295	COG0346	lactoylglutathione lyase activity
KvSKV_RS01300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KvSKV_RS01305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KvSKV_RS01315	COG1309	transcriptional regulator
KvSKV_RS01320	COG1764	response to oxidative stress
KvSKV_RS01350	COG4608	Belongs to the ABC transporter superfamily
KvSKV_RS01355	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS01360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS01365	COG0601	transmembrane transport
KvSKV_RS01375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KvSKV_RS01380	COG0747	negative chemotaxis
KvSKV_RS01385	COG0583	DNA-binding transcription factor activity
KvSKV_RS01390	COG1802	Transcriptional regulator
KvSKV_RS01395	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KvSKV_RS01410	COG0765	amino acid transport
KvSKV_RS01415	COG1126	abc transporter atp-binding protein
KvSKV_RS01425	COG1063	alcohol dehydrogenase
KvSKV_RS01440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KvSKV_RS01445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KvSKV_RS01450	COG2814	Major facilitator Superfamily
KvSKV_RS01455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KvSKV_RS01460	COG0142	geranyltranstransferase activity
KvSKV_RS01465	COG1722	exodeoxyribonuclease VII activity
KvSKV_RS01470	COG2835	tetraacyldisaccharide 4'-kinase activity
KvSKV_RS01495	COG1999	signal sequence binding
KvSKV_RS01510	COG1858	cytochrome C peroxidase
KvSKV_RS01555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KvSKV_RS01595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KvSKV_RS01605	COG1132	(ABC) transporter
KvSKV_RS01620	COG1294	oxidase, subunit
KvSKV_RS01630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KvSKV_RS01635	COG4988	ABC transporter
KvSKV_RS01645	COG2814	Major facilitator Superfamily
KvSKV_RS01650	COG0640	Transcriptional regulator
KvSKV_RS01655	COG0789	Transcriptional regulator
KvSKV_RS01675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KvSKV_RS01675	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KvSKV_RS01685	COG0521	Mo-molybdopterin cofactor biosynthetic process
KvSKV_RS01690	COG1573	uracil-dna glycosylase
KvSKV_RS01715	COG0469	pyruvate kinase activity
KvSKV_RS01725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KvSKV_RS01730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KvSKV_RS01740	COG0072	phenylalanine-tRNA ligase activity
KvSKV_RS01740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KvSKV_RS01745	COG0625	glutathione transferase activity
KvSKV_RS01785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KvSKV_RS01800	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KvSKV_RS01805	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KvSKV_RS01825	COG2943	transferase activity, transferring hexosyl groups
KvSKV_RS01835	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KvSKV_RS01845	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KvSKV_RS01855	COG0778	Nitroreductase
KvSKV_RS01860	COG1872	DUF167
KvSKV_RS01870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KvSKV_RS01880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KvSKV_RS01890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KvSKV_RS01895	COG0792	nuclease activity
KvSKV_RS01905	COG0606	chelatase, subunit chli
KvSKV_RS01915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KvSKV_RS01920	COG0756	dUTP diphosphatase activity
KvSKV_RS01925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KvSKV_RS01930	COG0339	signal peptide processing
KvSKV_RS01935	COG0765	amino acid transport
KvSKV_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KvSKV_RS01945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KvSKV_RS01960	COG1079	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS01965	COG4603	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS01980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KvSKV_RS02020	COG1120	ATPase activity
KvSKV_RS02025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KvSKV_RS02040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KvSKV_RS02070	COG1309	transcriptional regulator
KvSKV_RS02095	COG0587	DNA-directed DNA polymerase activity
KvSKV_RS02120	COG0673	inositol 2-dehydrogenase activity
KvSKV_RS02130	COG1609	Transcriptional regulator
KvSKV_RS02140	COG1172	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS02150	COG1879	ABC-type sugar transport system periplasmic component
KvSKV_RS02165	COG0012	GTP binding
KvSKV_RS02170	COG1252	NADH dehydrogenase
KvSKV_RS02180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KvSKV_RS02185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KvSKV_RS02205	COG0288	reversible hydration of carbon dioxide
KvSKV_RS02215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KvSKV_RS02220	COG0791	NLP P60 protein
KvSKV_RS02240	COG0679	Auxin Efflux Carrier
KvSKV_RS02245	COG1671	Belongs to the UPF0178 family
KvSKV_RS02250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KvSKV_RS02265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KvSKV_RS02275	COG0129	dihydroxy-acid dehydratase activity
KvSKV_RS02290	COG0024	Methionine aminopeptidase
KvSKV_RS02295	COG1546	Belongs to the CinA family
KvSKV_RS02295	COG1058	Belongs to the CinA family
KvSKV_RS02310	COG0742	ribosomal rna small subunit methyltransferase
KvSKV_RS02320	COG0678	peroxiredoxin activity
KvSKV_RS02325	COG2154	pterin-4-alpha-carbinolamine dehydratase
KvSKV_RS02335	COG0251	oxidation-reduction process
KvSKV_RS02345	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KvSKV_RS02355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KvSKV_RS02360	COG0347	Belongs to the P(II) protein family
KvSKV_RS02365	COG0004	ammonium transporteR
KvSKV_RS02375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KvSKV_RS02380	COG3474	cytochrome
KvSKV_RS02385	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KvSKV_RS02400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KvSKV_RS02405	COG0741	lytic transglycosylase activity
KvSKV_RS02410	COG1959	2 iron, 2 sulfur cluster binding
KvSKV_RS02420	COG1609	Transcriptional regulator
KvSKV_RS02435	COG0395	ABC-type sugar transport system, permease component
KvSKV_RS02445	COG3842	ATPase activity
KvSKV_RS02480	COG1522	sequence-specific DNA binding
KvSKV_RS02500	COG1305	Transglutaminase-like
KvSKV_RS02505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KvSKV_RS02520	COG2814	Major facilitator Superfamily
KvSKV_RS02535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KvSKV_RS02540	COG1116	anion transmembrane transporter activity
KvSKV_RS02550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KvSKV_RS02565	COG0252	asparaginase activity
KvSKV_RS02570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KvSKV_RS02575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KvSKV_RS02580	COG4208	sulfate ABC transporter
KvSKV_RS02595	COG2937	Belongs to the GPAT DAPAT family
KvSKV_RS02600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KvSKV_RS02605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KvSKV_RS02610	COG1131	(ABC) transporter
KvSKV_RS02615	COG0842	Transport permease protein
KvSKV_RS02630	COG0322	excinuclease ABC activity
KvSKV_RS02635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KvSKV_RS02645	COG0314	molybdopterin synthase activity
KvSKV_RS02655	COG0697	spore germination
KvSKV_RS02665	COG2264	protein methyltransferase activity
KvSKV_RS02670	COG0142	geranyltranstransferase activity
KvSKV_RS02675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KvSKV_RS02690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KvSKV_RS02715	COG0009	L-threonylcarbamoyladenylate synthase
KvSKV_RS02725	COG2885	chlorophyll binding
KvSKV_RS02735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KvSKV_RS02750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KvSKV_RS02760	COG0540	Belongs to the ATCase OTCase family
KvSKV_RS02770	COG0825	malonyl-CoA metabolic process
KvSKV_RS02775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KvSKV_RS02790	COG2884	Cell division ATP-binding protein ftsE
KvSKV_RS02805	COG0019	diaminopimelate decarboxylase activity
KvSKV_RS02815	COG0165	Argininosuccinate lyase
KvSKV_RS02820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KvSKV_RS02830	COG1678	Uncharacterized ACR, COG1678
KvSKV_RS02835	COG1381	Involved in DNA repair and RecF pathway recombination
KvSKV_RS02845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KvSKV_RS02850	COG0571	ribonuclease III activity
KvSKV_RS02855	COG0681	Belongs to the peptidase S26 family
KvSKV_RS02860	COG0736	holo-[acyl-carrier-protein] synthase activity
KvSKV_RS02865	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KvSKV_RS02880	COG1758	RNA polymerase activity
KvSKV_RS02890	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KvSKV_RS02895	COG0328	RNA-DNA hybrid ribonuclease activity
KvSKV_RS02910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KvSKV_RS02915	COG0242	peptide deformylase activity
KvSKV_RS02920	COG0242	peptide deformylase activity
KvSKV_RS02925	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KvSKV_RS02940	COG0435	Glutathione S-transferase
KvSKV_RS02945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KvSKV_RS02965	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KvSKV_RS02970	COG0799	negative regulation of ribosome biogenesis
KvSKV_RS02975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KvSKV_RS02980	COG0066	3-isopropylmalate dehydratase activity
KvSKV_RS02990	COG0473	3-isopropylmalate dehydrogenase activity
KvSKV_RS02995	COG0697	spore germination
KvSKV_RS03015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KvSKV_RS03035	COG3616	Alanine racemase, N-terminal domain
KvSKV_RS03045	COG0789	Transcriptional regulator
KvSKV_RS03065	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS03070	COG4989	oxidoreductase activity
KvSKV_RS03080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KvSKV_RS03080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KvSKV_RS03085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KvSKV_RS03090	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KvSKV_RS03105	COG0667	Aldo Keto reductase
KvSKV_RS03110	COG0628	permease
KvSKV_RS03130	COG1609	Transcriptional regulator
KvSKV_RS03140	COG3842	ATPase activity
KvSKV_RS03145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KvSKV_RS03150	COG1177	transmembrane transport
KvSKV_RS03170	COG0803	Belongs to the bacterial solute-binding protein 9 family
KvSKV_RS03185	COG0251	oxidation-reduction process
KvSKV_RS03190	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS03195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS03205	COG0747	negative chemotaxis
KvSKV_RS03210	COG1802	Transcriptional regulator
KvSKV_RS03215	COG4993	Dehydrogenase
KvSKV_RS03240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KvSKV_RS03260	COG2267	carboxylic ester hydrolase activity
KvSKV_RS03275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KvSKV_RS03280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KvSKV_RS03425	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KvSKV_RS03445	COG0539	negative regulation of cytoplasmic translation
KvSKV_RS03450	COG0776	regulation of translation
KvSKV_RS03460	COG0135	phosphoribosylanthranilate isomerase activity
KvSKV_RS03470	COG0133	tryptophan synthase activity
KvSKV_RS03480	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KvSKV_RS03490	COG0159	tryptophan synthase activity
KvSKV_RS03500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KvSKV_RS03510	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS03515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS03520	COG0601	transmembrane transport
KvSKV_RS03525	COG0747	negative chemotaxis
KvSKV_RS03530	COG0277	FAD linked oxidase domain protein
KvSKV_RS03545	COG1702	phosphate starvation-inducible protein PhoH
KvSKV_RS03550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KvSKV_RS03555	COG4535	Mg2 and Co2 transporter CorC
KvSKV_RS03560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KvSKV_RS03565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KvSKV_RS03575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KvSKV_RS03580	COG0174	glutamine synthetase
KvSKV_RS03585	COG0519	Catalyzes the synthesis of GMP from XMP
KvSKV_RS03585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KvSKV_RS03590	COG0174	glutamine synthetase
KvSKV_RS03595	COG4160	amino acid transport
KvSKV_RS03600	COG4215	(ABC) transporter
KvSKV_RS03615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KvSKV_RS03620	COG0504	CTP synthase activity
KvSKV_RS03630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KvSKV_RS03650	COG1570	exodeoxyribonuclease VII activity
KvSKV_RS03655	COG0312	modulator of DNA gyrase
KvSKV_RS03665	COG0109	protoheme IX farnesyltransferase activity
KvSKV_RS03675	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KvSKV_RS03695	COG0612	Peptidase, M16
KvSKV_RS03700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KvSKV_RS03710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KvSKV_RS03715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KvSKV_RS03725	COG0747	negative chemotaxis
KvSKV_RS03730	COG0601	transmembrane transport
KvSKV_RS03735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS03740	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS03765	COG1278	Cold shock
KvSKV_RS03775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KvSKV_RS03790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KvSKV_RS03800	COG0772	Belongs to the SEDS family
KvSKV_RS03805	COG0768	penicillin binding
KvSKV_RS03840	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KvSKV_RS03845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KvSKV_RS03875	COG0564	pseudouridine synthase activity
KvSKV_RS03890	COG1072	(Pantothenic acid kinase))
KvSKV_RS03915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KvSKV_RS03920	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KvSKV_RS03925	COG1329	Transcriptional regulator
KvSKV_RS03930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KvSKV_RS03940	COG0330	HflC and HflK could
KvSKV_RS03945	COG0330	HflC and HflK could
KvSKV_RS03950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KvSKV_RS03980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KvSKV_RS03985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KvSKV_RS04005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KvSKV_RS04015	COG1435	thymidine kinase activity
KvSKV_RS04020	COG2010	Cytochrome c
KvSKV_RS04025	COG1136	(ABC) transporter
KvSKV_RS04035	COG0442	prolyl-tRNA aminoacylation
KvSKV_RS04040	COG0628	permease
KvSKV_RS04050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KvSKV_RS04055	COG0248	Ppx GppA phosphatase
KvSKV_RS04070	COG0180	Tryptophanyl-tRNA synthetase
KvSKV_RS04085	COG0730	response to heat
KvSKV_RS04100	COG4603	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS04105	COG3845	ABC transporter
KvSKV_RS04110	COG1744	ABC transporter substrate-binding protein PnrA-like
KvSKV_RS04120	COG1214	PFAM Peptidase M22, glycoprotease
KvSKV_RS04125	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KvSKV_RS04140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KvSKV_RS04145	COG1278	Cold shock
KvSKV_RS04155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KvSKV_RS04170	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KvSKV_RS04180	COG0829	nickel cation binding
KvSKV_RS04185	COG0831	urea catabolic process
KvSKV_RS04190	COG0832	Belongs to the urease beta subunit family
KvSKV_RS04195	COG0804	urea catabolic process
KvSKV_RS04200	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KvSKV_RS04210	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KvSKV_RS04225	COG2514	catechol 2,3-dioxygenase activity
KvSKV_RS04230	COG0435	Glutathione S-transferase
KvSKV_RS04235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KvSKV_RS04240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KvSKV_RS04250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KvSKV_RS04255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KvSKV_RS04260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KvSKV_RS04270	COG0456	acetyltransferase
KvSKV_RS04285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KvSKV_RS04300	COG0077	Prephenate dehydratase
KvSKV_RS04300	COG1605	Chorismate mutase
KvSKV_RS04310	COG4166	transmembrane transport
KvSKV_RS04315	COG4174	ABC transporter (Permease)
KvSKV_RS04320	COG4239	(ABC) transporter, permease
KvSKV_RS04325	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS04330	COG1686	Belongs to the peptidase S11 family
KvSKV_RS04340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KvSKV_RS04345	COG2813	Specifically methylates the guanine in position
KvSKV_RS04355	COG0408	coproporphyrinogen oxidase activity
KvSKV_RS04360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KvSKV_RS04365	COG0181	hydroxymethylbilane synthase activity
KvSKV_RS04370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KvSKV_RS04375	COG0287	Prephenate dehydrogenase
KvSKV_RS04395	COG2862	Uncharacterized protein family, UPF0114
KvSKV_RS04400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KvSKV_RS04405	COG2226	methyltransferase
KvSKV_RS04415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KvSKV_RS04425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KvSKV_RS04430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KvSKV_RS04435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KvSKV_RS04440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KvSKV_RS04445	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KvSKV_RS04465	COG2983	Belongs to the UPF0260 family
KvSKV_RS04470	COG0196	riboflavin kinase activity
KvSKV_RS04480	COG1227	inorganic diphosphatase activity
KvSKV_RS04490	COG0459	protein refolding
KvSKV_RS04495	COG0346	lactoylglutathione lyase activity
KvSKV_RS04505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KvSKV_RS04515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KvSKV_RS04520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KvSKV_RS04530	COG0071	Belongs to the small heat shock protein (HSP20) family
KvSKV_RS04545	COG0492	ferredoxin-NADP+ reductase activity
KvSKV_RS04550	COG1522	sequence-specific DNA binding
KvSKV_RS04555	COG1496	oxidoreductase activity
KvSKV_RS04565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KvSKV_RS04575	COG0735	belongs to the Fur family
KvSKV_RS04595	COG0463	Glycosyl transferase, family 2
KvSKV_RS04600	COG4604	ABC transporter, ATP-binding protein
KvSKV_RS04605	COG4605	iron ion homeostasis
KvSKV_RS04610	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KvSKV_RS04615	COG4607	ABC-type enterochelin transport system periplasmic component
KvSKV_RS04630	COG4214	carbohydrate transport
KvSKV_RS04635	COG1129	ABC transporter
KvSKV_RS04650	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KvSKV_RS04665	COG2351	hydroxyisourate hydrolase activity
KvSKV_RS04670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KvSKV_RS04675	COG2217	Heavy metal translocating P-type atpase
KvSKV_RS04680	COG2111	Na H antiporter
KvSKV_RS04680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KvSKV_RS04685	COG1006	Multisubunit Na H antiporter MnhC subunit
KvSKV_RS04690	COG0651	ATP synthesis coupled electron transport
KvSKV_RS04695	COG1863	multisubunit Na H antiporter MnhE subunit
KvSKV_RS04700	COG2212	antiporter activity
KvSKV_RS04705	COG1320	monovalent cation:proton antiporter activity
KvSKV_RS04725	COG0574	Belongs to the PEP-utilizing enzyme family
KvSKV_RS04725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KvSKV_RS04730	COG3773	Cell wall hydrolase
KvSKV_RS04730	COG3409	Peptidoglycan-binding domain 1 protein
KvSKV_RS04735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KvSKV_RS04760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KvSKV_RS04770	COG1802	Transcriptional regulator
KvSKV_RS04780	COG0505	Belongs to the CarA family
KvSKV_RS04790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KvSKV_RS04795	COG1309	transcriptional regulator
KvSKV_RS04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS04825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS04835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KvSKV_RS04840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KvSKV_RS04855	COG0789	Transcriptional regulator
KvSKV_RS04860	COG1122	ATPase activity
KvSKV_RS04870	COG1268	BioY protein
KvSKV_RS04885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KvSKV_RS04890	COG0667	Aldo Keto reductase
KvSKV_RS04935	COG0552	protein localization to endoplasmic reticulum
KvSKV_RS04940	COG2917	probably involved in intracellular septation
KvSKV_RS04955	COG1609	Transcriptional regulator
KvSKV_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS05000	COG0251	oxidation-reduction process
KvSKV_RS05005	COG3964	amidohydrolase
KvSKV_RS05010	COG3142	Participates in the control of copper homeostasis
KvSKV_RS05020	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS05025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS05030	COG0601	transmembrane transport
KvSKV_RS05040	COG0747	negative chemotaxis
KvSKV_RS05055	COG0295	cytidine deaminase activity
KvSKV_RS05060	COG0402	S-adenosylhomocysteine deaminase activity
KvSKV_RS05075	COG3845	ABC transporter
KvSKV_RS05080	COG4603	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS05085	COG1079	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS05110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KvSKV_RS05115	COG0215	cysteine-tRNA ligase activity
KvSKV_RS05130	COG2989	Protein conserved in bacteria
KvSKV_RS05135	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KvSKV_RS05145	COG0433	COG0433 Predicted ATPase
KvSKV_RS05150	COG4974	Belongs to the 'phage' integrase family
KvSKV_RS05165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KvSKV_RS05170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KvSKV_RS05180	COG0629	single-stranded DNA binding
KvSKV_RS05185	COG0741	lytic transglycosylase activity
KvSKV_RS05200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KvSKV_RS05205	COG0528	UMP kinase activity
KvSKV_RS05210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KvSKV_RS05215	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KvSKV_RS05220	COG0047	phosphoribosylformylglycinamidine synthase activity
KvSKV_RS05230	COG2204	response regulator
KvSKV_RS05240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KvSKV_RS05245	COG0303	'Molybdopterin
KvSKV_RS05250	COG0315	cyclic pyranopterin monophosphate synthase activity
KvSKV_RS05260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KvSKV_RS05265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KvSKV_RS05280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KvSKV_RS05295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KvSKV_RS05300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KvSKV_RS05310	COG1278	Cold shock
KvSKV_RS05330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KvSKV_RS05345	COG0556	nucleotide-excision repair
KvSKV_RS05380	COG1131	(ABC) transporter
KvSKV_RS05410	COG0544	peptidyl-prolyl cis-trans isomerase activity
KvSKV_RS05415	COG0737	Belongs to the 5'-nucleotidase family
KvSKV_RS05420	COG0359	binds to the 23S rRNA
KvSKV_RS05425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KvSKV_RS05430	COG0360	Binds together with S18 to 16S ribosomal RNA
KvSKV_RS05440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KvSKV_RS05450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KvSKV_RS05460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KvSKV_RS05465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KvSKV_RS05480	COG4695	Portal protein
KvSKV_RS05565	COG0508	dehydrogenase complex catalyzes the overall conversion of
KvSKV_RS05570	COG0022	dehydrogenase e1 component
KvSKV_RS05570	COG0508	dehydrogenase complex catalyzes the overall conversion of
KvSKV_RS05575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KvSKV_RS05585	COG1830	Aldolase
KvSKV_RS05590	COG0126	phosphoglycerate kinase activity
KvSKV_RS05605	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KvSKV_RS05615	COG0440	acetolactate synthase activity
KvSKV_RS05620	COG0028	Belongs to the TPP enzyme family
KvSKV_RS05625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KvSKV_RS05630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KvSKV_RS05635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KvSKV_RS05655	COG0534	Mate efflux family protein
KvSKV_RS05660	COG0586	Pfam SNARE associated Golgi protein
KvSKV_RS05690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KvSKV_RS05700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KvSKV_RS05715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KvSKV_RS05720	COG0156	8-amino-7-oxononanoate synthase activity
KvSKV_RS05725	COG1426	Protein conserved in bacteria
KvSKV_RS05730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KvSKV_RS05740	COG0436	Aminotransferase
KvSKV_RS05745	COG0860	N-Acetylmuramoyl-L-alanine amidase
KvSKV_RS05750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KvSKV_RS05755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KvSKV_RS05830	COG3750	Belongs to the UPF0335 family
KvSKV_RS05855	COG3237	CsbD-like
KvSKV_RS06050	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
KvSKV_RS06075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KvSKV_RS06080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KvSKV_RS06085	COG4592	Periplasmic binding protein
KvSKV_RS06095	COG1120	ATPase activity
KvSKV_RS06105	COG4774	siderophore transport
KvSKV_RS06105	COG1629	transport
KvSKV_RS06180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KvSKV_RS06185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KvSKV_RS06190	COG2166	iron-sulfur cluster assembly
KvSKV_RS06200	COG1802	Transcriptional regulator
KvSKV_RS06215	COG0840	transmembrane signaling receptor activity
KvSKV_RS06240	COG0517	IMP dehydrogenase activity
KvSKV_RS06240	COG0516	GMP reductase activity
KvSKV_RS06250	COG1546	Belongs to the CinA family
KvSKV_RS06260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KvSKV_RS06260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KvSKV_RS06270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KvSKV_RS06275	COG3852	Histidine kinase
KvSKV_RS06280	COG2204	response regulator
KvSKV_RS06285	COG5000	phosphorelay sensor kinase activity
KvSKV_RS06290	COG2204	response regulator
KvSKV_RS06310	COG0583	DNA-binding transcription factor activity
KvSKV_RS06320	COG0477	Major facilitator Superfamily
KvSKV_RS06365	COG4771	TonB-dependent receptor
KvSKV_RS06370	COG4178	(ABC) transporter
KvSKV_RS06380	COG2375	cellular response to nickel ion
KvSKV_RS06385	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KvSKV_RS06405	COG3842	ATPase activity
KvSKV_RS06410	COG1177	transmembrane transport
KvSKV_RS06415	COG1176	ABC-type spermidine putrescine transport system, permease component I
KvSKV_RS06425	COG1999	signal sequence binding
KvSKV_RS06435	COG2059	Chromate
KvSKV_RS06495	COG2084	Dehydrogenase
KvSKV_RS06525	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KvSKV_RS06535	COG0194	GDP metabolic process
KvSKV_RS06565	COG5265	(ABC) transporter
KvSKV_RS06580	COG1160	GTP binding
KvSKV_RS06585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KvSKV_RS06595	COG1862	Preprotein translocase
KvSKV_RS06600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KvSKV_RS06610	COG4133	protoheme IX ABC transporter activity
KvSKV_RS06615	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KvSKV_RS06620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KvSKV_RS06630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KvSKV_RS06665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KvSKV_RS06670	COG0416	fatty acid biosynthetic process
KvSKV_RS06675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KvSKV_RS06690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KvSKV_RS06700	COG0488	(ABC) transporter
KvSKV_RS06710	COG3956	TIGRFAM MazG family protein
KvSKV_RS06715	COG1473	amidohydrolase
KvSKV_RS06720	COG0010	Belongs to the arginase family
KvSKV_RS06725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KvSKV_RS06730	COG0305	Participates in initiation and elongation during chromosome replication
KvSKV_RS06735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KvSKV_RS06740	COG0418	dihydroorotase activity
KvSKV_RS06750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KvSKV_RS06765	COG0149	triose-phosphate isomerase activity
KvSKV_RS06770	COG0316	Belongs to the HesB IscA family
KvSKV_RS06775	COG2151	metal-sulfur cluster biosynthetic enzyme
KvSKV_RS06780	COG0343	queuine tRNA-ribosyltransferase activity
KvSKV_RS06785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KvSKV_RS06790	COG1923	regulation of RNA biosynthetic process
KvSKV_RS06795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KvSKV_RS06800	COG2814	Major facilitator Superfamily
KvSKV_RS06810	COG4166	transmembrane transport
KvSKV_RS06815	COG2313	pseudouridylate synthase activity
KvSKV_RS06825	COG0052	Belongs to the universal ribosomal protein uS2 family
KvSKV_RS06830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KvSKV_RS06855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS06870	COG4771	TonB-dependent receptor
KvSKV_RS06880	COG4558	Periplasmic binding protein
KvSKV_RS06890	COG1522	sequence-specific DNA binding
KvSKV_RS06900	COG1268	BioY protein
KvSKV_RS06910	COG0673	inositol 2-dehydrogenase activity
KvSKV_RS06915	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS06925	COG1940	carbohydrate kinase activity
KvSKV_RS06930	COG0747	negative chemotaxis
KvSKV_RS06940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS06945	COG1940	carbohydrate kinase activity
KvSKV_RS06950	COG3142	Participates in the control of copper homeostasis
KvSKV_RS06970	COG0154	amidase activity
KvSKV_RS06975	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS06980	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS06990	COG0601	transmembrane transport
KvSKV_RS07005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KvSKV_RS07020	COG3191	aminopeptidase activity
KvSKV_RS07035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KvSKV_RS07040	COG0719	Fe-S assembly protein
KvSKV_RS07045	COG0396	ATPase activity
KvSKV_RS07055	COG0719	Fe-S assembly protein
KvSKV_RS07070	COG2945	thiolester hydrolase activity
KvSKV_RS07090	COG2076	Multidrug Resistance protein
KvSKV_RS07095	COG1217	gtp-binding protein TYPA
KvSKV_RS07105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KvSKV_RS07135	COG4608	Belongs to the ABC transporter superfamily
KvSKV_RS07140	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS07150	COG0601	transmembrane transport
KvSKV_RS07155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS07165	COG2267	carboxylic ester hydrolase activity
KvSKV_RS07200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS07230	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS07235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS07240	COG0601	transmembrane transport
KvSKV_RS07250	COG0778	Nitroreductase
KvSKV_RS07295	COG2315	Protein conserved in bacteria
KvSKV_RS07305	COG1473	amidohydrolase
KvSKV_RS07310	COG0747	negative chemotaxis
KvSKV_RS07315	COG0601	transmembrane transport
KvSKV_RS07325	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS07330	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KvSKV_RS07340	COG0488	(ABC) transporter
KvSKV_RS07350	COG0402	S-adenosylhomocysteine deaminase activity
KvSKV_RS07355	COG1733	regulation of RNA biosynthetic process
KvSKV_RS07360	COG3447	MASE1 domain protein
KvSKV_RS07360	COG5001	Diguanylate cyclase
KvSKV_RS07360	COG5002	protein histidine kinase activity
KvSKV_RS07380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KvSKV_RS07395	COG1278	Cold shock
KvSKV_RS07435	COG2321	neutral zinc metallopeptidase
KvSKV_RS07440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KvSKV_RS07460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KvSKV_RS07465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KvSKV_RS07480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KvSKV_RS07485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KvSKV_RS07500	COG0482	sulfurtransferase activity
KvSKV_RS07505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KvSKV_RS07515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KvSKV_RS07520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KvSKV_RS07530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KvSKV_RS07535	COG0750	zinc metalloprotease
KvSKV_RS07540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KvSKV_RS07550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KvSKV_RS07555	COG0233	cytoplasmic translational termination
KvSKV_RS07590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KvSKV_RS07590	COG1116	anion transmembrane transporter activity
KvSKV_RS07600	COG1473	amidohydrolase
KvSKV_RS07605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KvSKV_RS07635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KvSKV_RS07645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS07655	COG0747	negative chemotaxis
KvSKV_RS07665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KvSKV_RS07675	COG1464	Belongs to the NlpA lipoprotein family
KvSKV_RS07690	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KvSKV_RS07695	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KvSKV_RS07700	COG1473	amidohydrolase
KvSKV_RS07710	COG3842	ATPase activity
KvSKV_RS07715	COG1177	transmembrane transport
KvSKV_RS07735	COG0300	oxidoreductase activity
KvSKV_RS07740	COG3806	Anti-sigma factor
KvSKV_RS07745	COG1595	DNA-templated transcription, initiation
KvSKV_RS07765	COG0415	Belongs to the DNA photolyase family
KvSKV_RS07780	COG0251	oxidation-reduction process
KvSKV_RS07785	COG0785	Cytochrome C biogenesis protein
KvSKV_RS07805	COG1780	Probably involved in ribonucleotide reductase function
KvSKV_RS07810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KvSKV_RS07815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KvSKV_RS07825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KvSKV_RS07830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KvSKV_RS07835	COG0509	glycine decarboxylation via glycine cleavage system
KvSKV_RS07865	COG1522	sequence-specific DNA binding
KvSKV_RS07870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KvSKV_RS07885	COG4208	sulfate ABC transporter
KvSKV_RS07890	COG3264	Mechanosensitive ion channel
KvSKV_RS07890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KvSKV_RS07905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KvSKV_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS07935	COG0114	fumarate hydratase activity
KvSKV_RS07960	COG0166	Belongs to the GPI family
KvSKV_RS07970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KvSKV_RS07995	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KvSKV_RS08000	COG0105	UTP biosynthetic process
KvSKV_RS08005	COG0488	(ABC) transporter
KvSKV_RS08010	COG3300	MHYT domain
KvSKV_RS08010	COG5001	Diguanylate cyclase
KvSKV_RS08015	COG2095	MarC family integral membrane protein
KvSKV_RS08020	COG3577	Aspartyl protease
KvSKV_RS08045	COG0434	BtpA family
KvSKV_RS08070	COG1349	DNA-binding transcription factor activity
KvSKV_RS08085	COG0307	riboflavin synthase, alpha
KvSKV_RS08095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KvSKV_RS08100	COG0795	lipopolysaccharide-transporting ATPase activity
KvSKV_RS08120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KvSKV_RS08125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KvSKV_RS08135	COG2890	protein-(glutamine-N5) methyltransferase activity
KvSKV_RS08140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KvSKV_RS08150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KvSKV_RS08155	COG1309	transcriptional regulator
KvSKV_RS08160	COG3842	ATPase activity
KvSKV_RS08170	COG1176	ABC-type spermidine putrescine transport system, permease component I
KvSKV_RS08180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KvSKV_RS08185	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KvSKV_RS08190	COG1612	heme a metabolic process
KvSKV_RS08205	COG2867	negative regulation of translational initiation
KvSKV_RS08210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KvSKV_RS08230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KvSKV_RS08230	COG0519	Catalyzes the synthesis of GMP from XMP
KvSKV_RS08240	COG4235	cytochrome complex assembly
KvSKV_RS08245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KvSKV_RS08250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KvSKV_RS08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS08285	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KvSKV_RS08295	COG0248	Ppx GppA phosphatase
KvSKV_RS08300	COG0837	glucose binding
KvSKV_RS08315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KvSKV_RS08340	COG2308	Evidence 4 Homologs of previously reported genes of
KvSKV_RS08350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KvSKV_RS08360	COG1519	Transferase
KvSKV_RS08365	COG0438	transferase activity, transferring glycosyl groups
KvSKV_RS08370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KvSKV_RS08380	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KvSKV_RS08390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KvSKV_RS08395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KvSKV_RS08400	COG0308	aminopeptidase N
KvSKV_RS08410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KvSKV_RS08440	COG1733	regulation of RNA biosynthetic process
KvSKV_RS08455	COG0511	ligase activity, forming carbon-carbon bonds
KvSKV_RS08460	COG0439	Biotin carboxylase
KvSKV_RS08465	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KvSKV_RS08480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KvSKV_RS08485	COG0740	serine-type endopeptidase activity
KvSKV_RS08505	COG1295	ribonuclease BN
KvSKV_RS08510	COG0033	Phosphoglucomutase
KvSKV_RS08525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KvSKV_RS08535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KvSKV_RS08540	COG0358	DNA primase activity
KvSKV_RS08545	COG1253	flavin adenine dinucleotide binding
KvSKV_RS08550	COG3622	Belongs to the hyi family
KvSKV_RS08570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KvSKV_RS08575	COG3768	UPF0283 membrane protein
KvSKV_RS08580	COG3106	COG3106 Predicted ATPase
KvSKV_RS08585	COG0101	tRNA pseudouridine synthase activity
KvSKV_RS08590	COG0729	surface antigen
KvSKV_RS08600	COG0758	DNA mediated transformation
KvSKV_RS08605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KvSKV_RS08605	COG1754	DNA topoisomerase type I activity
KvSKV_RS08610	COG0840	transmembrane signaling receptor activity
KvSKV_RS08620	COG2201	protein-glutamate methylesterase activity
KvSKV_RS08630	COG0745	RESPONSE REGULATOR receiver
KvSKV_RS08645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KvSKV_RS08650	COG0745	RESPONSE REGULATOR receiver
KvSKV_RS08660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KvSKV_RS08670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KvSKV_RS08675	COG4608	Belongs to the ABC transporter superfamily
KvSKV_RS08680	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS08685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS08690	COG0601	transmembrane transport
KvSKV_RS08720	COG0006	proline dipeptidase activity
KvSKV_RS08725	COG0583	DNA-binding transcription factor activity
KvSKV_RS08730	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
KvSKV_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS08740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KvSKV_RS08745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KvSKV_RS08750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KvSKV_RS08750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KvSKV_RS08780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KvSKV_RS08785	COG2186	Transcriptional regulator
KvSKV_RS08790	COG2079	MmgE PrpD family protein
KvSKV_RS08815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KvSKV_RS08860	COG0306	phosphate transporter
KvSKV_RS08870	COG2204	response regulator
KvSKV_RS08875	COG4191	Histidine kinase
KvSKV_RS08880	COG1301	dicarboxylic acid transport
KvSKV_RS08885	COG2814	Major facilitator Superfamily
KvSKV_RS08890	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KvSKV_RS08920	COG0300	oxidoreductase activity
KvSKV_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS08930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KvSKV_RS08935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KvSKV_RS08950	COG0438	transferase activity, transferring glycosyl groups
KvSKV_RS08965	COG0438	transferase activity, transferring glycosyl groups
KvSKV_RS08985	COG0730	response to heat
KvSKV_RS09000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KvSKV_RS09005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS09015	COG2186	Transcriptional regulator
KvSKV_RS09025	COG3842	ATPase activity
KvSKV_RS09030	COG0366	Alpha amylase catalytic
KvSKV_RS09035	COG0395	ABC-type sugar transport system, permease component
KvSKV_RS09040	COG1175	transmembrane transport
KvSKV_RS09045	COG1653	transport
KvSKV_RS09055	COG2723	6-phospho-beta-galactosidase activity
KvSKV_RS09065	COG1794	racemase activity, acting on amino acids and derivatives
KvSKV_RS09090	COG0659	secondary active sulfate transmembrane transporter activity
KvSKV_RS09095	COG4221	oxidoreductase activity
KvSKV_RS09100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KvSKV_RS09115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KvSKV_RS09125	COG0511	ligase activity, forming carbon-carbon bonds
KvSKV_RS09140	COG0436	Aminotransferase
KvSKV_RS09145	COG1609	Transcriptional regulator
KvSKV_RS09150	COG3265	gluconokinase activity
KvSKV_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS09160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KvSKV_RS09165	COG1063	alcohol dehydrogenase
KvSKV_RS09170	COG0583	DNA-binding transcription factor activity
KvSKV_RS09200	COG3842	ATPase activity
KvSKV_RS09205	COG1840	ABC-type Fe3 transport system, periplasmic component
KvSKV_RS09210	COG3842	ATPase activity
KvSKV_RS09215	COG1177	transmembrane transport
KvSKV_RS09220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KvSKV_RS09225	COG0583	DNA-binding transcription factor activity
KvSKV_RS09260	COG1518	maintenance of DNA repeat elements
KvSKV_RS09265	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KvSKV_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
KvSKV_RS09275	COG0410	ABC transporter
KvSKV_RS09305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KvSKV_RS09325	COG0477	Major facilitator Superfamily
KvSKV_RS09330	COG0154	amidase activity
KvSKV_RS09340	COG1653	transport
KvSKV_RS09355	COG0395	ABC-type sugar transport system, permease component
KvSKV_RS09380	COG1335	isochorismatase
KvSKV_RS09425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KvSKV_RS09430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS09435	COG0601	transmembrane transport
KvSKV_RS09470	COG2094	Belongs to the DNA glycosylase MPG family
KvSKV_RS09485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KvSKV_RS09500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KvSKV_RS09505	COG0297	glycogen (starch) synthase activity
KvSKV_RS09510	COG3386	PFAM SMP-30 Gluconolaconase
KvSKV_RS09520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KvSKV_RS09525	COG3387	PFAM Glycoside hydrolase 15-related
KvSKV_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS09560	COG2814	Major facilitator Superfamily
KvSKV_RS09565	COG1414	Transcriptional regulator
KvSKV_RS09570	COG0444	Belongs to the ABC transporter superfamily
KvSKV_RS09575	COG4608	Belongs to the ABC transporter superfamily
KvSKV_RS09590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS09595	COG0402	S-adenosylhomocysteine deaminase activity
KvSKV_RS09615	COG1476	TRANSCRIPTIONal
KvSKV_RS09630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KvSKV_RS09680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KvSKV_RS09685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KvSKV_RS09700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KvSKV_RS09715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KvSKV_RS09725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KvSKV_RS09735	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KvSKV_RS09745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KvSKV_RS09750	COG0739	heme binding
KvSKV_RS09765	COG3453	Protein conserved in bacteria
KvSKV_RS09765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KvSKV_RS09775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KvSKV_RS09790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KvSKV_RS09800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KvSKV_RS09815	COG0275	rRNA processing
KvSKV_RS09820	COG2001	Belongs to the MraZ family
KvSKV_RS09830	COG0489	protein tyrosine kinase activity
KvSKV_RS09845	COG3135	benzoate transporter
KvSKV_RS09855	COG0210	DNA helicase
KvSKV_RS09860	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KvSKV_RS09865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KvSKV_RS09875	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KvSKV_RS09885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KvSKV_RS09890	COG0849	cell division
KvSKV_RS09900	COG1181	Belongs to the D-alanine--D-alanine ligase family
KvSKV_RS09905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KvSKV_RS09910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KvSKV_RS09915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KvSKV_RS09930	COG2081	HI0933 family
KvSKV_RS09935	COG3750	Belongs to the UPF0335 family
KvSKV_RS09955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KvSKV_RS10000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KvSKV_RS10005	COG0714	Associated with various cellular activities
KvSKV_RS10035	COG0071	Belongs to the small heat shock protein (HSP20) family
KvSKV_RS10045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KvSKV_RS10045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KvSKV_RS10070	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KvSKV_RS10085	COG0805	protein transport
KvSKV_RS10090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KvSKV_RS10095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KvSKV_RS10110	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KvSKV_RS10120	COG3720	iron ion transport
KvSKV_RS10125	COG4558	Periplasmic binding protein
KvSKV_RS10130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KvSKV_RS10135	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KvSKV_RS10145	COG0573	inorganic phosphate transmembrane transporter activity
KvSKV_RS10155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KvSKV_RS10160	COG0704	Plays a role in the regulation of phosphate uptake
KvSKV_RS10165	COG0745	RESPONSE REGULATOR receiver
KvSKV_RS10200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS10210	COG1116	anion transmembrane transporter activity
KvSKV_RS10215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KvSKV_RS10240	COG0500	methyltransferase
KvSKV_RS10320	COG0110	maltose O-acetyltransferase activity
KvSKV_RS10435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KvSKV_RS10440	COG0784	Response regulator, receiver
KvSKV_RS10440	COG4191	Histidine kinase
KvSKV_RS10480	COG3750	Belongs to the UPF0335 family
KvSKV_RS10525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KvSKV_RS10540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KvSKV_RS10555	COG0629	single-stranded DNA binding
KvSKV_RS10570	COG4974	Belongs to the 'phage' integrase family
KvSKV_RS10590	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KvSKV_RS10600	COG3088	subunit of a heme lyase
KvSKV_RS10605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KvSKV_RS10610	COG0424	maF-like protein
KvSKV_RS10615	COG1530	ribonuclease E activity
KvSKV_RS10620	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KvSKV_RS10630	COG1132	(ABC) transporter
KvSKV_RS10645	COG0752	glycyl-tRNA synthetase alpha subunit
KvSKV_RS10655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KvSKV_RS10665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KvSKV_RS10670	COG0019	diaminopimelate decarboxylase activity
KvSKV_RS10690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KvSKV_RS10690	COG0116	Belongs to the methyltransferase superfamily
KvSKV_RS10695	COG0251	oxidation-reduction process
KvSKV_RS10705	COG0402	S-adenosylhomocysteine deaminase activity
KvSKV_RS10715	COG2249	NAD(P)H dehydrogenase (quinone) activity
KvSKV_RS10725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS10735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KvSKV_RS10745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KvSKV_RS10770	COG2182	Extracellular solute-binding protein
KvSKV_RS10775	COG1175	transmembrane transport
KvSKV_RS10780	COG0395	ABC-type sugar transport system, permease component
KvSKV_RS10785	COG0165	Argininosuccinate lyase
KvSKV_RS10790	COG3842	ATPase activity
KvSKV_RS10795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KvSKV_RS10800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KvSKV_RS10805	COG0569	domain protein
KvSKV_RS10835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KvSKV_RS10845	COG0697	spore germination
KvSKV_RS10850	COG0148	phosphopyruvate hydratase activity
KvSKV_RS10865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KvSKV_RS10870	COG0372	Belongs to the citrate synthase family
KvSKV_RS10875	COG3088	subunit of a heme lyase
KvSKV_RS10880	COG1138	Cytochrome C-type biogenesis protein
KvSKV_RS10885	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KvSKV_RS10890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KvSKV_RS10895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KvSKV_RS10900	COG0583	DNA-binding transcription factor activity
KvSKV_RS10905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KvSKV_RS10910	COG0271	Belongs to the BolA IbaG family
KvSKV_RS10915	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KvSKV_RS10930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KvSKV_RS10950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KvSKV_RS10960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KvSKV_RS10965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KvSKV_RS10985	COG0590	tRNA wobble adenosine to inosine editing
KvSKV_RS10990	COG1187	pseudouridine synthase activity
KvSKV_RS11010	COG4260	virion core protein, lumpy skin disease virus
KvSKV_RS11025	COG1490	D-aminoacyl-tRNA deacylase activity
KvSKV_RS11030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KvSKV_RS11035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KvSKV_RS11040	COG0037	tRNA processing
KvSKV_RS11050	COG2885	chlorophyll binding
KvSKV_RS11055	COG0823	Involved in the tonB-independent uptake of proteins
KvSKV_RS11075	COG0824	Thioesterase
KvSKV_RS11085	COG2255	four-way junction helicase activity
KvSKV_RS11090	COG0632	four-way junction helicase activity
KvSKV_RS11105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KvSKV_RS11110	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KvSKV_RS11115	COG0124	histidyl-tRNA synthetase
KvSKV_RS11130	COG5507	3-demethylubiquinone-9 3-methyltransferase
KvSKV_RS11145	COG3895	Periplasmic Protein
KvSKV_RS11150	COG0737	Belongs to the 5'-nucleotidase family
KvSKV_RS11160	COG0167	dihydroorotate dehydrogenase activity
KvSKV_RS11195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KvSKV_RS11200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KvSKV_RS11205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KvSKV_RS11210	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KvSKV_RS11225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KvSKV_RS11230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KvSKV_RS11240	COG2267	carboxylic ester hydrolase activity
KvSKV_RS11245	COG0481	GTPase activity
KvSKV_RS11260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KvSKV_RS11270	COG1643	Atp-dependent helicase
KvSKV_RS11280	COG3932	Exopolysaccharide synthesis, ExoD
KvSKV_RS11285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KvSKV_RS11290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KvSKV_RS11305	COG1464	Belongs to the NlpA lipoprotein family
KvSKV_RS11310	COG3237	CsbD-like
KvSKV_RS11320	COG1027	Aspartate ammonia-lyase
KvSKV_RS11345	COG0848	biopolymer transport protein
KvSKV_RS11355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KvSKV_RS11370	COG1522	sequence-specific DNA binding
KvSKV_RS11375	COG0506	proline dehydrogenase activity
KvSKV_RS11375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KvSKV_RS11375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KvSKV_RS11380	COG0483	inositol monophosphate 1-phosphatase activity
KvSKV_RS11400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KvSKV_RS11405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KvSKV_RS11420	COG1132	(ABC) transporter
KvSKV_RS11425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KvSKV_RS11435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KvSKV_RS11465	COG0625	glutathione transferase activity
KvSKV_RS11470	COG0187	DNA topoisomerase II activity
KvSKV_RS11480	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KvSKV_RS11495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KvSKV_RS11525	COG0217	transcriptional regulatory protein
KvSKV_RS11530	COG1692	metallophosphoesterase
KvSKV_RS11540	COG2239	Acts as a magnesium transporter
KvSKV_RS11545	COG0402	S-adenosylhomocysteine deaminase activity
KvSKV_RS11550	COG1522	sequence-specific DNA binding
KvSKV_RS11555	COG2814	Major facilitator Superfamily
KvSKV_RS11560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KvSKV_RS11565	COG0483	inositol monophosphate 1-phosphatase activity
KvSKV_RS11575	COG0583	DNA-binding transcription factor activity
KvSKV_RS11585	COG0670	Belongs to the BI1 family
KvSKV_RS11615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KvSKV_RS11635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KvSKV_RS11640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KvSKV_RS11645	COG1472	Belongs to the glycosyl hydrolase 3 family
KvSKV_RS11655	COG0018	arginyl-trna synthetase
KvSKV_RS11680	COG1007	ATP synthesis coupled electron transport
KvSKV_RS11695	COG0713	ATP synthesis coupled electron transport
KvSKV_RS11705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KvSKV_RS11710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KvSKV_RS11745	COG0649	NAD binding
KvSKV_RS11755	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KvSKV_RS11765	COG0546	phosphoglycolate phosphatase activity
KvSKV_RS11770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KvSKV_RS11800	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KvSKV_RS11810	COG4771	TonB-dependent receptor
KvSKV_RS11820	COG1464	Belongs to the NlpA lipoprotein family
KvSKV_RS11830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KvSKV_RS11835	COG2011	ABC-type metal ion transport system permease component
KvSKV_RS11855	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS11865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS11870	COG0601	transmembrane transport
KvSKV_RS11915	COG1802	Transcriptional regulator
KvSKV_RS11930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KvSKV_RS11935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KvSKV_RS11940	COG1012	belongs to the aldehyde dehydrogenase family
KvSKV_RS11955	COG2995	paraquat-inducible protein a
KvSKV_RS11965	COG0131	Imidazoleglycerol-phosphate dehydratase
KvSKV_RS11970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KvSKV_RS11975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KvSKV_RS11980	COG0107	imidazoleglycerol-phosphate synthase activity
KvSKV_RS11985	COG0140	phosphoribosyl-ATP diphosphatase activity
KvSKV_RS11995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KvSKV_RS12005	COG0697	spore germination
KvSKV_RS12015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KvSKV_RS12020	COG1335	isochorismatase
KvSKV_RS12025	COG0251	oxidation-reduction process
KvSKV_RS12030	COG2267	carboxylic ester hydrolase activity
KvSKV_RS12045	COG0848	biopolymer transport protein
KvSKV_RS12060	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KvSKV_RS12065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KvSKV_RS12080	COG1957	nucleoside hydrolase
KvSKV_RS12095	COG1172	Belongs to the binding-protein-dependent transport system permease family
KvSKV_RS12110	COG2514	catechol 2,3-dioxygenase activity
KvSKV_RS12125	COG0725	ABC transporter, periplasmic molybdate-binding protein
KvSKV_RS12130	COG4149	molybdate abc transporter
KvSKV_RS12135	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KvSKV_RS12150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KvSKV_RS12180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KvSKV_RS12185	COG0612	Peptidase, M16
KvSKV_RS12190	COG0612	Peptidase, M16
KvSKV_RS12205	COG0138	bifunctional purine biosynthesis protein purh
KvSKV_RS12230	COG0346	lactoylglutathione lyase activity
KvSKV_RS12240	COG0450	alkyl hydroperoxide reductase
KvSKV_RS12245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KvSKV_RS12255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KvSKV_RS12260	COG0268	Binds directly to 16S ribosomal RNA
KvSKV_RS12270	COG2226	methyltransferase
KvSKV_RS12280	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KvSKV_RS12310	COG5443	negative regulation of bacterial-type flagellum assembly
KvSKV_RS12325	COG1815	bacterial-type flagellum-dependent cell motility
KvSKV_RS12330	COG1558	bacterial-type flagellum-dependent cell motility
KvSKV_RS12335	COG1677	Flagellar hook-basal body complex protein FliE
KvSKV_RS12340	COG1987	bacterial-type flagellum assembly
KvSKV_RS12345	COG4786	Flagellar basal body rod
KvSKV_RS12350	COG4786	Flagellar basal body rod
KvSKV_RS12360	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KvSKV_RS12375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KvSKV_RS12385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KvSKV_RS12405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KvSKV_RS12435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KvSKV_RS12440	COG1338	Plays a role in the flagellum-specific transport system
KvSKV_RS12445	COG1706	bacterial-type flagellum-dependent cell motility
KvSKV_RS12460	COG1749	Flagellar hook protein flgE
KvSKV_RS12465	COG1360	Flagellar Motor Protein
KvSKV_RS12510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KvSKV_RS12515	COG0154	amidase activity
KvSKV_RS12530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KvSKV_RS12550	COG1686	Belongs to the peptidase S11 family
KvSKV_RS12555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KvSKV_RS12565	COG0084	hydrolase, TatD family'
KvSKV_RS12570	COG0321	lipoyl(octanoyl) transferase activity
KvSKV_RS12570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KvSKV_RS12635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KvSKV_RS12660	COG4166	transmembrane transport
KvSKV_RS12665	COG0601	transmembrane transport
KvSKV_RS12670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS12675	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS12685	COG0754	glutathionylspermidine amidase activity
KvSKV_RS12690	COG5463	Belongs to the UPF0441 family
KvSKV_RS12695	COG1509	lysine 2,3-aminomutase activity
KvSKV_RS12705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KvSKV_RS12715	COG0175	sulfate reduction
KvSKV_RS12720	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KvSKV_RS12735	COG0395	ABC-type sugar transport system, permease component
KvSKV_RS12840	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KvSKV_RS12840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KvSKV_RS12855	COG3781	membrane
KvSKV_RS12860	COG0535	radical SAM domain protein
KvSKV_RS12865	COG0535	radical SAM domain protein
KvSKV_RS12870	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KvSKV_RS12875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KvSKV_RS12930	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KvSKV_RS12940	COG4770	biotin carboxylase activity
KvSKV_RS12945	COG1984	allophanate hydrolase subunit 2
KvSKV_RS12960	COG2205	protein histidine kinase activity
KvSKV_RS12985	COG0024	Methionine aminopeptidase
KvSKV_RS12990	COG2832	Protein of unknown function (DUF454)
KvSKV_RS12995	COG1733	regulation of RNA biosynthetic process
KvSKV_RS13000	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KvSKV_RS13015	COG2169	Transcriptional regulator
KvSKV_RS13015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KvSKV_RS13030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KvSKV_RS13035	COG0594	ribonuclease P activity
KvSKV_RS13040	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KvSKV_RS13045	COG0037	tRNA processing
KvSKV_RS13050	COG0706	membrane insertase activity
KvSKV_RS13065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KvSKV_RS13080	COG1126	abc transporter atp-binding protein
KvSKV_RS13085	COG0765	amino acid transport
KvSKV_RS13090	COG4597	amino acid ABC transporter
KvSKV_RS13095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KvSKV_RS13105	COG0546	phosphoglycolate phosphatase activity
KvSKV_RS13115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KvSKV_RS13140	COG0203	ribosomal protein L17
KvSKV_RS13145	COG0202	RNA polymerase activity
KvSKV_RS13150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KvSKV_RS13155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KvSKV_RS13160	COG0563	adenylate kinase activity
KvSKV_RS13165	COG0201	protein transport
KvSKV_RS13170	COG0200	Binds to the 23S rRNA
KvSKV_RS13175	COG1841	ribosomal large subunit assembly
KvSKV_RS13180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KvSKV_RS13185	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KvSKV_RS13195	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KvSKV_RS13200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KvSKV_RS13205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KvSKV_RS13210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KvSKV_RS13225	COG0255	Belongs to the universal ribosomal protein uL29 family
KvSKV_RS13230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KvSKV_RS13235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KvSKV_RS13240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KvSKV_RS13245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KvSKV_RS13250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KvSKV_RS13255	COG0089	rRNA binding
KvSKV_RS13260	COG0088	Forms part of the polypeptide exit tunnel
KvSKV_RS13265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KvSKV_RS13270	COG0051	transcription antitermination factor activity, RNA binding
KvSKV_RS13275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KvSKV_RS13290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KvSKV_RS13295	COG0697	spore germination
KvSKV_RS13305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KvSKV_RS13315	COG0222	ribosome binding
KvSKV_RS13320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KvSKV_RS13325	COG0081	regulation of translation
KvSKV_RS13330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KvSKV_RS13335	COG0250	Participates in transcription elongation, termination and antitermination
KvSKV_RS13340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KvSKV_RS13365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KvSKV_RS13370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KvSKV_RS13385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KvSKV_RS13395	COG0793	Belongs to the peptidase S41A family
KvSKV_RS13400	COG0494	nUDIX hydrolase
KvSKV_RS13405	COG0557	exoribonuclease II activity
KvSKV_RS13410	COG1028	Short-chain dehydrogenase reductase Sdr
KvSKV_RS13435	COG2171	N-acyltransferase activity
KvSKV_RS13445	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KvSKV_RS13490	COG0714	Associated with various cellular activities
KvSKV_RS13505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KvSKV_RS13530	COG2309	aminopeptidase activity
KvSKV_RS13545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KvSKV_RS13550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KvSKV_RS13555	COG1121	(ABC) transporter
KvSKV_RS13580	COG3842	ATPase activity
KvSKV_RS13585	COG0395	ABC-type sugar transport system, permease component
KvSKV_RS13590	COG1175	transmembrane transport
KvSKV_RS13600	COG0584	glycerophosphoryl diester phosphodiesterase
KvSKV_RS13610	COG1253	flavin adenine dinucleotide binding
KvSKV_RS13615	COG1247	-acetyltransferase
KvSKV_RS13625	COG1088	dTDP-glucose 4,6-dehydratase activity
KvSKV_RS13635	COG0747	negative chemotaxis
KvSKV_RS13640	COG0601	transmembrane transport
KvSKV_RS13645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KvSKV_RS13650	COG4172	Belongs to the ABC transporter superfamily
KvSKV_RS13655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KvSKV_RS13685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KvSKV_RS13690	COG2350	Protein conserved in bacteria
KvSKV_RS13700	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KvSKV_RS13715	COG1137	ATPase activity
KvSKV_RS13720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KvSKV_RS13725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KvSKV_RS13740	COG0534	Mate efflux family protein
KvSKV_RS13770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KvSKV_RS13775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KvSKV_RS13795	COG2003	Belongs to the UPF0758 family
KvSKV_RS13810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KvSKV_RS13815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KvSKV_RS13820	COG0494	nUDIX hydrolase
KvSKV_RS13825	COG1902	pentaerythritol trinitrate reductase activity
KvSKV_RS13840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KvSKV_RS13845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KvSKV_RS13850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KvSKV_RS13865	COG0779	Required for maturation of 30S ribosomal subunits
KvSKV_RS13890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KvSKV_RS13895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KvSKV_RS13900	COG1040	competence protein
KvSKV_RS13925	COG3034	peptidoglycan biosynthetic process
KvSKV_RS13935	COG0617	tRNA 3'-terminal CCA addition
KvSKV_RS13945	COG0494	nUDIX hydrolase
KvSKV_RS13955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KvSKV_RS13960	COG0137	argininosuccinate synthase activity
KvSKV_RS13985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KvSKV_RS13990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KvSKV_RS13995	COG1420	regulation of RNA biosynthetic process
KvSKV_RS14000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KvSKV_RS14005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KvSKV_RS14010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KvSKV_RS14030	COG0445	tRNA wobble uridine modification
KvSKV_RS14035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KvSKV_RS14040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KvSKV_RS14400	COG0564	pseudouridine synthase activity
KvSKV_RS14505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KvSKV_RS14625	COG0542	response to heat
KvSKV_RS14925	COG1410	methionine synthase
KvSKV_RS14925	COG0646	methionine synthase
KvSKV_RS14970	COG0336	Belongs to the RNA methyltransferase TrmD family
KvSKV_RS14990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KvSKV_RS15275	COG0747	negative chemotaxis