locus-tag	class	description
KVU_0001	COG1120	ATPase activity
KVU_0002	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KVU_0003	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KVU_0005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KVU_0014	COG0587	DNA-directed DNA polymerase activity
KVU_0019	COG0673	inositol 2-dehydrogenase activity
KVU_0021	COG1609	Transcriptional regulator
KVU_0024	COG0012	GTP binding
KVU_0025	COG1252	NADH dehydrogenase
KVU_0027	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KVU_0028	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KVU_0032	COG0288	reversible hydration of carbon dioxide
KVU_0034	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KVU_0036	COG0791	NLP P60 protein
KVU_0039	COG0679	Auxin Efflux Carrier
KVU_0040	COG1671	Belongs to the UPF0178 family
KVU_0041	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KVU_0044	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KVU_0046	COG0129	dihydroxy-acid dehydratase activity
KVU_0050	COG1546	Belongs to the CinA family
KVU_0050	COG1058	Belongs to the CinA family
KVU_0052	COG0742	ribosomal rna small subunit methyltransferase
KVU_0055	COG0678	peroxiredoxin activity
KVU_0056	COG2154	pterin-4-alpha-carbinolamine dehydratase
KVU_0058	COG0251	oxidation-reduction process
KVU_0061	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KVU_0063	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KVU_0065	COG0004	ammonium transporteR
KVU_0067	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KVU_0068	COG3474	cytochrome
KVU_0069	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KVU_0072	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KVU_0073	COG0741	lytic transglycosylase activity
KVU_0074	COG1959	2 iron, 2 sulfur cluster binding
KVU_0075	COG1609	Transcriptional regulator
KVU_0078	COG0395	ABC-type sugar transport system, permease component
KVU_0080	COG3842	ATPase activity
KVU_0085	COG1522	sequence-specific DNA binding
KVU_0089	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVU_0090	COG1305	Transglutaminase-like
KVU_0093	COG2814	Major facilitator Superfamily
KVU_0096	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVU_0097	COG1116	anion transmembrane transporter activity
KVU_0098	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KVU_0102	COG0252	asparaginase activity
KVU_0103	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KVU_0104	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KVU_0105	COG4208	sulfate ABC transporter
KVU_0108	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KVU_0109	COG2937	Belongs to the GPAT DAPAT family
KVU_0110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KVU_0111	COG1131	(ABC) transporter
KVU_0112	COG0842	Transport permease protein
KVU_0115	COG0322	excinuclease ABC activity
KVU_0116	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KVU_0118	COG0314	molybdopterin synthase activity
KVU_0120	COG0697	spore germination
KVU_0122	COG2264	protein methyltransferase activity
KVU_0123	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KVU_0124	COG0142	geranyltranstransferase activity
KVU_0127	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KVU_0133	COG0009	L-threonylcarbamoyladenylate synthase
KVU_0134	COG2885	chlorophyll binding
KVU_0136	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KVU_0139	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KVU_0141	COG0540	Belongs to the ATCase OTCase family
KVU_0146	COG2884	Cell division ATP-binding protein ftsE
KVU_0149	COG0019	diaminopimelate decarboxylase activity
KVU_0151	COG0165	Argininosuccinate lyase
KVU_0152	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KVU_0154	COG1381	Involved in DNA repair and RecF pathway recombination
KVU_0155	COG1678	Uncharacterized ACR, COG1678
KVU_0157	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KVU_0158	COG0571	ribonuclease III activity
KVU_0159	COG0681	Belongs to the peptidase S26 family
KVU_0160	COG0736	holo-[acyl-carrier-protein] synthase activity
KVU_0161	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KVU_0164	COG1758	RNA polymerase activity
KVU_0166	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KVU_0167	COG0328	RNA-DNA hybrid ribonuclease activity
KVU_0169	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KVU_0171	COG0242	peptide deformylase activity
KVU_0172	COG0242	peptide deformylase activity
KVU_0173	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KVU_0176	COG0435	Glutathione S-transferase
KVU_0177	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KVU_0181	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KVU_0182	COG0799	negative regulation of ribosome biogenesis
KVU_0184	COG0473	3-isopropylmalate dehydrogenase activity
KVU_0185	COG0697	spore germination
KVU_0188	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KVU_0190	COG3616	Alanine racemase, N-terminal domain
KVU_0192	COG0789	Transcriptional regulator
KVU_0195	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_0197	COG4989	oxidoreductase activity
KVU_0199	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KVU_0199	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KVU_0200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KVU_0204	COG0667	Aldo Keto reductase
KVU_0205	COG0628	permease
KVU_0209	COG1609	Transcriptional regulator
KVU_0210	COG1177	transmembrane transport
KVU_0211	COG3842	ATPase activity
KVU_0212	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KVU_0213	COG1177	transmembrane transport
KVU_0217	COG0803	Belongs to the bacterial solute-binding protein 9 family
KVU_0220	COG0251	oxidation-reduction process
KVU_0221	COG4172	Belongs to the ABC transporter superfamily
KVU_0222	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0224	COG0747	negative chemotaxis
KVU_0225	COG1802	Transcriptional regulator
KVU_0226	COG4993	Dehydrogenase
KVU_0229	COG2010	Cytochrome c
KVU_0229	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KVU_0230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KVU_0234	COG2267	carboxylic ester hydrolase activity
KVU_0238	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KVU_0239	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KVU_0255	COG1215	transferase activity, transferring glycosyl groups
KVU_0258	COG2223	nitrite transmembrane transporter activity
KVU_0259	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KVU_0261	COG4139	cobalamin transport
KVU_0265	COG0539	negative regulation of cytoplasmic translation
KVU_0266	COG0776	regulation of translation
KVU_0268	COG0135	phosphoribosylanthranilate isomerase activity
KVU_0270	COG0133	tryptophan synthase activity
KVU_0272	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KVU_0274	COG0159	tryptophan synthase activity
KVU_0275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KVU_0277	COG4172	Belongs to the ABC transporter superfamily
KVU_0278	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0279	COG0601	transmembrane transport
KVU_0280	COG0747	negative chemotaxis
KVU_0281	COG0277	FAD linked oxidase domain protein
KVU_0284	COG1702	phosphate starvation-inducible protein PhoH
KVU_0285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KVU_0286	COG4535	Mg2 and Co2 transporter CorC
KVU_0287	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KVU_0288	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KVU_0290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVU_0291	COG0174	glutamine synthetase
KVU_0292	COG0519	Catalyzes the synthesis of GMP from XMP
KVU_0292	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KVU_0293	COG0174	glutamine synthetase
KVU_0294	COG4160	amino acid transport
KVU_0295	COG4215	(ABC) transporter
KVU_0298	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KVU_0299	COG0504	CTP synthase activity
KVU_0302	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KVU_0303	COG0151	Belongs to the GarS family
KVU_0305	COG1570	exodeoxyribonuclease VII activity
KVU_0306	COG0312	modulator of DNA gyrase
KVU_0308	COG0109	protoheme IX farnesyltransferase activity
KVU_0310	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KVU_0314	COG0612	Peptidase, M16
KVU_0315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KVU_0316	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KVU_0318	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KVU_0320	COG0747	negative chemotaxis
KVU_0321	COG0601	transmembrane transport
KVU_0322	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0323	COG0444	Belongs to the ABC transporter superfamily
KVU_0326	COG1278	Cold shock
KVU_0328	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KVU_0330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KVU_0332	COG0772	Belongs to the SEDS family
KVU_0333	COG0768	penicillin binding
KVU_0339	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KVU_0340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KVU_0345	COG0564	pseudouridine synthase activity
KVU_0348	COG1072	(Pantothenic acid kinase))
KVU_0353	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KVU_0354	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KVU_0355	COG1329	Transcriptional regulator
KVU_0356	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KVU_0358	COG0330	HflC and HflK could
KVU_0359	COG0330	HflC and HflK could
KVU_0360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KVU_0365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KVU_0366	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KVU_0370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KVU_0371	COG1435	thymidine kinase activity
KVU_0373	COG2010	Cytochrome c
KVU_0374	COG1136	(ABC) transporter
KVU_0376	COG0442	prolyl-tRNA aminoacylation
KVU_0377	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KVU_0378	COG0248	Ppx GppA phosphatase
KVU_0381	COG0180	Tryptophanyl-tRNA synthetase
KVU_0384	COG0730	response to heat
KVU_0386	COG1079	Belongs to the binding-protein-dependent transport system permease family
KVU_0387	COG4603	Belongs to the binding-protein-dependent transport system permease family
KVU_0388	COG3845	ABC transporter
KVU_0389	COG1744	ABC transporter substrate-binding protein PnrA-like
KVU_0391	COG1214	PFAM Peptidase M22, glycoprotease
KVU_0392	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KVU_0395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KVU_0396	COG1278	Cold shock
KVU_0397	COG0488	(ABC) transporter
KVU_0398	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KVU_0400	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KVU_0402	COG0829	nickel cation binding
KVU_0403	COG0831	urea catabolic process
KVU_0404	COG0832	Belongs to the urease beta subunit family
KVU_0405	COG0804	urea catabolic process
KVU_0406	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KVU_0408	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KVU_0411	COG2514	catechol 2,3-dioxygenase activity
KVU_0412	COG0435	Glutathione S-transferase
KVU_0413	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KVU_0416	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KVU_0417	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KVU_0418	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KVU_0420	COG0456	acetyltransferase
KVU_0422	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KVU_0426	COG0077	Prephenate dehydratase
KVU_0426	COG1605	Chorismate mutase
KVU_0428	COG4166	transmembrane transport
KVU_0429	COG4174	ABC transporter (Permease)
KVU_0430	COG4239	(ABC) transporter, permease
KVU_0431	COG4172	Belongs to the ABC transporter superfamily
KVU_0432	COG1686	Belongs to the peptidase S11 family
KVU_0434	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KVU_0435	COG2813	Specifically methylates the guanine in position
KVU_0437	COG0408	coproporphyrinogen oxidase activity
KVU_0440	COG0181	hydroxymethylbilane synthase activity
KVU_0441	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KVU_0442	COG0287	Prephenate dehydrogenase
KVU_0446	COG2862	Uncharacterized protein family, UPF0114
KVU_0447	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KVU_0448	COG2226	methyltransferase
KVU_0450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KVU_0452	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KVU_0453	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KVU_0454	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KVU_0455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KVU_0456	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KVU_0459	COG2983	Belongs to the UPF0260 family
KVU_0460	COG0196	riboflavin kinase activity
KVU_0462	COG1227	inorganic diphosphatase activity
KVU_0465	COG0346	lactoylglutathione lyase activity
KVU_0466	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KVU_0469	COG0071	Belongs to the small heat shock protein (HSP20) family
KVU_0472	COG0492	ferredoxin-NADP+ reductase activity
KVU_0473	COG1522	sequence-specific DNA binding
KVU_0474	COG1496	oxidoreductase activity
KVU_0476	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KVU_0478	COG0735	belongs to the Fur family
KVU_0482	COG4604	ABC transporter, ATP-binding protein
KVU_0483	COG0463	Glycosyl transferase, family 2
KVU_0484	COG4607	ABC-type enterochelin transport system periplasmic component
KVU_0487	COG4214	carbohydrate transport
KVU_0488	COG1129	ABC transporter
KVU_0491	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KVU_0492	COG3257	ureidoglycine aminohydrolase activity
KVU_0494	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KVU_0495	COG2351	hydroxyisourate hydrolase activity
KVU_0496	COG2217	Heavy metal translocating P-type atpase
KVU_0497	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KVU_0497	COG2111	Na H antiporter
KVU_0498	COG1006	Multisubunit Na H antiporter MnhC subunit
KVU_0499	COG1863	multisubunit Na H antiporter MnhE subunit
KVU_0500	COG2212	antiporter activity
KVU_0501	COG1320	monovalent cation:proton antiporter activity
KVU_0505	COG0574	Belongs to the PEP-utilizing enzyme family
KVU_0505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KVU_0506	COG3409	Peptidoglycan-binding domain 1 protein
KVU_0506	COG3773	Cell wall hydrolase
KVU_0507	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KVU_0511	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KVU_0514	COG1802	Transcriptional regulator
KVU_0516	COG0505	Belongs to the CarA family
KVU_0518	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVU_0519	COG1309	transcriptional regulator
KVU_0524	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_0525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_0527	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KVU_0529	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KVU_0531	COG0789	Transcriptional regulator
KVU_0532	COG1122	ATPase activity
KVU_0534	COG1268	BioY protein
KVU_0537	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KVU_0539	COG0667	Aldo Keto reductase
KVU_0547	COG0552	protein localization to endoplasmic reticulum
KVU_0548	COG2917	probably involved in intracellular septation
KVU_0551	COG1609	Transcriptional regulator
KVU_0555	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_0558	COG0251	oxidation-reduction process
KVU_0559	COG3964	amidohydrolase
KVU_0561	COG3142	Participates in the control of copper homeostasis
KVU_0562	COG0444	Belongs to the ABC transporter superfamily
KVU_0563	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0564	COG0601	transmembrane transport
KVU_0566	COG0747	negative chemotaxis
KVU_0569	COG0295	cytidine deaminase activity
KVU_0570	COG0402	S-adenosylhomocysteine deaminase activity
KVU_0573	COG3845	ABC transporter
KVU_0574	COG4603	Belongs to the binding-protein-dependent transport system permease family
KVU_0575	COG1079	Belongs to the binding-protein-dependent transport system permease family
KVU_0580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KVU_0581	COG0215	cysteine-tRNA ligase activity
KVU_0584	COG2989	Protein conserved in bacteria
KVU_0585	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVU_0587	COG0433	COG0433 Predicted ATPase
KVU_0588	COG4974	Belongs to the 'phage' integrase family
KVU_0592	COG0629	single-stranded DNA binding
KVU_0594	COG0741	lytic transglycosylase activity
KVU_0596	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KVU_0597	COG0528	UMP kinase activity
KVU_0598	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KVU_0599	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KVU_0600	COG0047	phosphoribosylformylglycinamidine synthase activity
KVU_0602	COG2204	response regulator
KVU_0603	COG1530	ribonuclease E activity
KVU_0604	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KVU_0605	COG0303	'Molybdopterin
KVU_0606	COG0315	cyclic pyranopterin monophosphate synthase activity
KVU_0608	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KVU_0609	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KVU_0612	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KVU_0616	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KVU_0617	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KVU_0619	COG1278	Cold shock
KVU_0622	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KVU_0625	COG0556	nucleotide-excision repair
KVU_0631	COG1131	(ABC) transporter
KVU_0637	COG0544	peptidyl-prolyl cis-trans isomerase activity
KVU_0638	COG0737	Belongs to the 5'-nucleotidase family
KVU_0639	COG0359	binds to the 23S rRNA
KVU_0640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KVU_0641	COG0360	Binds together with S18 to 16S ribosomal RNA
KVU_0643	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KVU_0645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KVU_0647	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KVU_0648	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KVU_0650	COG4695	Portal protein
KVU_0667	COG0508	dehydrogenase complex catalyzes the overall conversion of
KVU_0668	COG0508	dehydrogenase complex catalyzes the overall conversion of
KVU_0668	COG0022	dehydrogenase e1 component
KVU_0669	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KVU_0671	COG1830	Aldolase
KVU_0672	COG0126	phosphoglycerate kinase activity
KVU_0675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KVU_0677	COG0440	acetolactate synthase activity
KVU_0678	COG0028	Belongs to the TPP enzyme family
KVU_0679	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KVU_0680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KVU_0681	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KVU_0683	COG0534	Mate efflux family protein
KVU_0684	COG0586	Pfam SNARE associated Golgi protein
KVU_0690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KVU_0692	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KVU_0695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KVU_0696	COG0156	8-amino-7-oxononanoate synthase activity
KVU_0697	COG1426	Protein conserved in bacteria
KVU_0698	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KVU_0700	COG0436	Aminotransferase
KVU_0701	COG0860	N-Acetylmuramoyl-L-alanine amidase
KVU_0702	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KVU_0703	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KVU_0717	COG3750	Belongs to the UPF0335 family
KVU_0722	COG3237	CsbD-like
KVU_0760	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
KVU_0765	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KVU_0766	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KVU_0767	COG4592	Periplasmic binding protein
KVU_0770	COG1120	ATPase activity
KVU_0771	COG1629	transport
KVU_0771	COG4774	siderophore transport
KVU_0783	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KVU_0785	COG2166	iron-sulfur cluster assembly
KVU_0786	COG1802	Transcriptional regulator
KVU_0789	COG0840	transmembrane signaling receptor activity
KVU_0794	COG0517	IMP dehydrogenase activity
KVU_0794	COG0516	GMP reductase activity
KVU_0796	COG1546	Belongs to the CinA family
KVU_0798	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KVU_0798	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KVU_0800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KVU_0801	COG3852	Histidine kinase
KVU_0802	COG2204	response regulator
KVU_0803	COG5000	phosphorelay sensor kinase activity
KVU_0804	COG2204	response regulator
KVU_0806	COG0583	DNA-binding transcription factor activity
KVU_0809	COG0477	Major facilitator Superfamily
KVU_0814	COG0745	RESPONSE REGULATOR receiver
KVU_0818	COG4771	TonB-dependent receptor
KVU_0820	COG4178	(ABC) transporter
KVU_0821	COG2375	cellular response to nickel ion
KVU_0822	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KVU_0826	COG3842	ATPase activity
KVU_0827	COG1177	transmembrane transport
KVU_0828	COG1176	ABC-type spermidine putrescine transport system, permease component I
KVU_0830	COG1999	signal sequence binding
KVU_0832	COG2059	Chromate
KVU_0843	COG2084	Dehydrogenase
KVU_0849	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KVU_0851	COG0194	GDP metabolic process
KVU_0857	COG5265	(ABC) transporter
KVU_0860	COG1160	GTP binding
KVU_0861	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KVU_0863	COG1862	Preprotein translocase
KVU_0864	COG4133	protoheme IX ABC transporter activity
KVU_0865	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KVU_0866	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KVU_0868	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KVU_0874	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KVU_0875	COG0416	fatty acid biosynthetic process
KVU_0876	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KVU_0879	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KVU_0881	COG0488	(ABC) transporter
KVU_0883	COG3956	TIGRFAM MazG family protein
KVU_0884	COG1473	amidohydrolase
KVU_0885	COG0010	Belongs to the arginase family
KVU_0886	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KVU_0887	COG0305	Participates in initiation and elongation during chromosome replication
KVU_0888	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KVU_0889	COG0418	dihydroorotase activity
KVU_0891	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KVU_0894	COG0149	triose-phosphate isomerase activity
KVU_0895	COG0316	Belongs to the HesB IscA family
KVU_0896	COG2151	metal-sulfur cluster biosynthetic enzyme
KVU_0897	COG0343	queuine tRNA-ribosyltransferase activity
KVU_0898	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KVU_0899	COG1923	regulation of RNA biosynthetic process
KVU_0900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KVU_0901	COG2814	Major facilitator Superfamily
KVU_0903	COG4166	transmembrane transport
KVU_0904	COG2313	pseudouridylate synthase activity
KVU_0911	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_0914	COG4771	TonB-dependent receptor
KVU_0917	COG4558	Periplasmic binding protein
KVU_0918	COG1522	sequence-specific DNA binding
KVU_0920	COG1268	BioY protein
KVU_0921	COG0673	inositol 2-dehydrogenase activity
KVU_0923	COG4172	Belongs to the ABC transporter superfamily
KVU_0925	COG1940	carbohydrate kinase activity
KVU_0926	COG0747	negative chemotaxis
KVU_0928	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0929	COG1940	carbohydrate kinase activity
KVU_0930	COG3142	Participates in the control of copper homeostasis
KVU_0934	COG0154	amidase activity
KVU_0935	COG4172	Belongs to the ABC transporter superfamily
KVU_0936	COG0444	Belongs to the ABC transporter superfamily
KVU_0937	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0938	COG0601	transmembrane transport
KVU_0941	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KVU_0944	COG3191	aminopeptidase activity
KVU_0946	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KVU_0947	COG0719	Fe-S assembly protein
KVU_0948	COG0396	ATPase activity
KVU_0950	COG0719	Fe-S assembly protein
KVU_0951	COG1104	cysteine desulfurase activity
KVU_0953	COG2945	thiolester hydrolase activity
KVU_0957	COG2076	Multidrug Resistance protein
KVU_0958	COG1217	gtp-binding protein TYPA
KVU_0960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KVU_0964	COG4608	Belongs to the ABC transporter superfamily
KVU_0965	COG0444	Belongs to the ABC transporter superfamily
KVU_0967	COG0601	transmembrane transport
KVU_0968	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0970	COG2267	carboxylic ester hydrolase activity
KVU_0977	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0983	COG0444	Belongs to the ABC transporter superfamily
KVU_0984	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_0985	COG0601	transmembrane transport
KVU_0987	COG0778	Nitroreductase
KVU_0996	COG2315	Protein conserved in bacteria
KVU_0998	COG1473	amidohydrolase
KVU_0999	COG0747	negative chemotaxis
KVU_1000	COG0601	transmembrane transport
KVU_1002	COG4172	Belongs to the ABC transporter superfamily
KVU_1003	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KVU_1006	COG0488	(ABC) transporter
KVU_1007	COG0402	S-adenosylhomocysteine deaminase activity
KVU_1008	COG1733	regulation of RNA biosynthetic process
KVU_1009	COG5002	protein histidine kinase activity
KVU_1009	COG5001	Diguanylate cyclase
KVU_1009	COG3447	MASE1 domain protein
KVU_1013	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KVU_1017	COG1278	Cold shock
KVU_1025	COG2321	neutral zinc metallopeptidase
KVU_1026	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KVU_1030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KVU_1031	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KVU_1034	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KVU_1035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KVU_1038	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVU_1039	COG0482	sulfurtransferase activity
KVU_1041	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVU_1042	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KVU_1044	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KVU_1045	COG0750	zinc metalloprotease
KVU_1046	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KVU_1048	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KVU_1049	COG0233	cytoplasmic translational termination
KVU_1056	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVU_1056	COG1116	anion transmembrane transporter activity
KVU_1058	COG1473	amidohydrolase
KVU_1059	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVU_1063	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVU_1065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1067	COG0747	negative chemotaxis
KVU_1069	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KVU_1070	COG2011	ABC-type metal ion transport system permease component
KVU_1071	COG1464	Belongs to the NlpA lipoprotein family
KVU_1074	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KVU_1075	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KVU_1077	COG1473	amidohydrolase
KVU_1078	COG3842	ATPase activity
KVU_1080	COG0300	oxidoreductase activity
KVU_1081	COG3806	Anti-sigma factor
KVU_1082	COG1595	DNA-templated transcription, initiation
KVU_1083	COG0415	Belongs to the DNA photolyase family
KVU_1087	COG0251	oxidation-reduction process
KVU_1088	COG0785	Cytochrome C biogenesis protein
KVU_1092	COG1780	Probably involved in ribonucleotide reductase function
KVU_1093	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KVU_1094	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KVU_1095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVU_1097	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KVU_1098	COG0509	glycine decarboxylation via glycine cleavage system
KVU_1104	COG1522	sequence-specific DNA binding
KVU_1105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KVU_1108	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KVU_1108	COG3264	Mechanosensitive ion channel
KVU_1109	COG4208	sulfate ABC transporter
KVU_1112	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KVU_1115	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_1117	COG0114	fumarate hydratase activity
KVU_1122	COG0166	Belongs to the GPI family
KVU_1124	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KVU_1127	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KVU_1128	COG0105	UTP biosynthetic process
KVU_1129	COG0488	(ABC) transporter
KVU_1130	COG5001	Diguanylate cyclase
KVU_1130	COG3300	MHYT domain
KVU_1131	COG2095	MarC family integral membrane protein
KVU_1132	COG3577	Aspartyl protease
KVU_1137	COG0434	BtpA family
KVU_1142	COG1349	DNA-binding transcription factor activity
KVU_1145	COG0307	riboflavin synthase, alpha
KVU_1146	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KVU_1147	COG0795	lipopolysaccharide-transporting ATPase activity
KVU_1151	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KVU_1152	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KVU_1154	COG2890	protein-(glutamine-N5) methyltransferase activity
KVU_1155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KVU_1157	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KVU_1158	COG3842	ATPase activity
KVU_1159	COG1309	transcriptional regulator
KVU_1161	COG1176	ABC-type spermidine putrescine transport system, permease component I
KVU_1163	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KVU_1164	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KVU_1165	COG1612	heme a metabolic process
KVU_1167	COG2867	negative regulation of translational initiation
KVU_1169	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KVU_1173	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KVU_1173	COG0519	Catalyzes the synthesis of GMP from XMP
KVU_1175	COG4235	cytochrome complex assembly
KVU_1176	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KVU_1177	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KVU_1182	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1186	COG0248	Ppx GppA phosphatase
KVU_1187	COG0837	glucose binding
KVU_1188	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVU_1193	COG2308	Evidence 4 Homologs of previously reported genes of
KVU_1195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KVU_1197	COG1519	Transferase
KVU_1198	COG0438	transferase activity, transferring glycosyl groups
KVU_1199	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVU_1201	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KVU_1203	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KVU_1204	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KVU_1205	COG0308	aminopeptidase N
KVU_1207	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KVU_1213	COG1733	regulation of RNA biosynthetic process
KVU_1216	COG0511	ligase activity, forming carbon-carbon bonds
KVU_1217	COG0439	Biotin carboxylase
KVU_1219	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KVU_1221	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KVU_1222	COG0740	serine-type endopeptidase activity
KVU_1226	COG1295	ribonuclease BN
KVU_1227	COG0033	Phosphoglucomutase
KVU_1229	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KVU_1232	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KVU_1233	COG0358	DNA primase activity
KVU_1234	COG1253	flavin adenine dinucleotide binding
KVU_1235	COG3622	Belongs to the hyi family
KVU_1239	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KVU_1240	COG3768	UPF0283 membrane protein
KVU_1241	COG3106	COG3106 Predicted ATPase
KVU_1242	COG0101	tRNA pseudouridine synthase activity
KVU_1243	COG0729	surface antigen
KVU_1246	COG0758	DNA mediated transformation
KVU_1247	COG1754	DNA topoisomerase type I activity
KVU_1247	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KVU_1248	COG0840	transmembrane signaling receptor activity
KVU_1250	COG2201	protein-glutamate methylesterase activity
KVU_1252	COG0745	RESPONSE REGULATOR receiver
KVU_1255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KVU_1256	COG0745	RESPONSE REGULATOR receiver
KVU_1258	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KVU_1260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KVU_1261	COG4608	Belongs to the ABC transporter superfamily
KVU_1262	COG0444	Belongs to the ABC transporter superfamily
KVU_1263	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1264	COG0601	transmembrane transport
KVU_1270	COG0583	DNA-binding transcription factor activity
KVU_1271	COG0006	proline dipeptidase activity
KVU_1272	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
KVU_1273	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_1274	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KVU_1275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVU_1276	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KVU_1276	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KVU_1282	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KVU_1283	COG2186	Transcriptional regulator
KVU_1284	COG2079	MmgE PrpD family protein
KVU_1289	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KVU_1292	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_1298	COG0306	phosphate transporter
KVU_1300	COG2204	response regulator
KVU_1301	COG4191	Histidine kinase
KVU_1302	COG1301	dicarboxylic acid transport
KVU_1303	COG2814	Major facilitator Superfamily
KVU_1304	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KVU_1310	COG0300	oxidoreductase activity
KVU_1311	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_1312	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KVU_1314	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KVU_1319	COG0730	response to heat
KVU_1322	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KVU_1323	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_1325	COG2186	Transcriptional regulator
KVU_1327	COG3842	ATPase activity
KVU_1328	COG0366	Alpha amylase catalytic
KVU_1329	COG0395	ABC-type sugar transport system, permease component
KVU_1330	COG1175	transmembrane transport
KVU_1331	COG1653	transport
KVU_1332	COG1609	Transcriptional regulator
KVU_1334	COG2723	6-phospho-beta-galactosidase activity
KVU_1335	COG1794	racemase activity, acting on amino acids and derivatives
KVU_1340	COG0659	secondary active sulfate transmembrane transporter activity
KVU_1341	COG4221	oxidoreductase activity
KVU_1342	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KVU_1345	COG0511	ligase activity, forming carbon-carbon bonds
KVU_1348	COG1609	Transcriptional regulator
KVU_1349	COG0436	Aminotransferase
KVU_1350	COG3265	gluconokinase activity
KVU_1351	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_1352	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KVU_1353	COG1063	alcohol dehydrogenase
KVU_1354	COG0583	DNA-binding transcription factor activity
KVU_1360	COG3842	ATPase activity
KVU_1361	COG1840	ABC-type Fe3 transport system, periplasmic component
KVU_1362	COG3842	ATPase activity
KVU_1363	COG1177	transmembrane transport
KVU_1364	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KVU_1365	COG0583	DNA-binding transcription factor activity
KVU_1371	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KVU_1372	COG1012	belongs to the aldehyde dehydrogenase family
KVU_1373	COG0410	ABC transporter
KVU_1379	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KVU_1384	COG0477	Major facilitator Superfamily
KVU_1385	COG0154	amidase activity
KVU_1388	COG0395	ABC-type sugar transport system, permease component
KVU_1393	COG1335	isochorismatase
KVU_1400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KVU_1401	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1402	COG0601	transmembrane transport
KVU_1408	COG2094	Belongs to the DNA glycosylase MPG family
KVU_1411	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVU_1414	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KVU_1415	COG0297	glycogen (starch) synthase activity
KVU_1416	COG3386	PFAM SMP-30 Gluconolaconase
KVU_1418	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KVU_1419	COG3387	PFAM Glycoside hydrolase 15-related
KVU_1420	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_1426	COG2814	Major facilitator Superfamily
KVU_1427	COG1414	Transcriptional regulator
KVU_1428	COG0444	Belongs to the ABC transporter superfamily
KVU_1429	COG4608	Belongs to the ABC transporter superfamily
KVU_1432	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1433	COG0402	S-adenosylhomocysteine deaminase activity
KVU_1437	COG1476	TRANSCRIPTIONal
KVU_1440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KVU_1444	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KVU_1445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KVU_1446	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KVU_1448	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KVU_1451	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KVU_1453	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KVU_1455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KVU_1457	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KVU_1458	COG0739	heme binding
KVU_1461	COG3453	Protein conserved in bacteria
KVU_1461	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KVU_1463	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KVU_1466	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KVU_1468	COG0275	rRNA processing
KVU_1469	COG2001	Belongs to the MraZ family
KVU_1471	COG0489	protein tyrosine kinase activity
KVU_1473	COG3135	benzoate transporter
KVU_1475	COG0210	DNA helicase
KVU_1476	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KVU_1477	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KVU_1479	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KVU_1480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KVU_1481	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KVU_1482	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KVU_1483	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KVU_1486	COG2081	HI0933 family
KVU_1487	COG3750	Belongs to the UPF0335 family
KVU_1491	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KVU_1500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KVU_1501	COG0714	Associated with various cellular activities
KVU_1507	COG0071	Belongs to the small heat shock protein (HSP20) family
KVU_1509	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KVU_1509	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KVU_1514	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KVU_1515	COG1971	Probably functions as a manganese efflux pump
KVU_1517	COG0805	protein transport
KVU_1518	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KVU_1519	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KVU_1522	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KVU_1525	COG0573	inorganic phosphate transmembrane transporter activity
KVU_1526	COG0581	inorganic phosphate transmembrane transporter activity
KVU_1527	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KVU_1528	COG0704	Plays a role in the regulation of phosphate uptake
KVU_1529	COG0745	RESPONSE REGULATOR receiver
KVU_1534	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_1535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_1536	COG1116	anion transmembrane transporter activity
KVU_1537	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVU_1543	COG0500	methyltransferase
KVU_1559	COG0110	maltose O-acetyltransferase activity
KVU_1580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KVU_1581	COG4191	Histidine kinase
KVU_1581	COG0784	Response regulator, receiver
KVU_1588	COG3750	Belongs to the UPF0335 family
KVU_1596	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KVU_1599	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KVU_1602	COG0629	single-stranded DNA binding
KVU_1604	COG4974	Belongs to the 'phage' integrase family
KVU_1607	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KVU_1608	COG5328	Belongs to the UPF0262 family
KVU_1609	COG3088	subunit of a heme lyase
KVU_1610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KVU_1611	COG0424	maF-like protein
KVU_1612	COG1530	ribonuclease E activity
KVU_1613	COG0318	PFAM AMP-dependent synthetase and ligase
KVU_1614	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KVU_1615	COG1132	(ABC) transporter
KVU_1618	COG0752	glycyl-tRNA synthetase alpha subunit
KVU_1620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KVU_1622	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KVU_1623	COG0019	diaminopimelate decarboxylase activity
KVU_1627	COG0116	Belongs to the methyltransferase superfamily
KVU_1627	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KVU_1628	COG0251	oxidation-reduction process
KVU_1630	COG0402	S-adenosylhomocysteine deaminase activity
KVU_1632	COG2249	NAD(P)H dehydrogenase (quinone) activity
KVU_1634	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVU_1640	COG2182	Extracellular solute-binding protein
KVU_1641	COG1175	transmembrane transport
KVU_1642	COG0395	ABC-type sugar transport system, permease component
KVU_1643	COG0165	Argininosuccinate lyase
KVU_1644	COG3842	ATPase activity
KVU_1645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KVU_1646	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KVU_1647	COG0569	domain protein
KVU_1652	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KVU_1654	COG0697	spore germination
KVU_1655	COG0148	phosphopyruvate hydratase activity
KVU_1658	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KVU_1659	COG0372	Belongs to the citrate synthase family
KVU_1660	COG3088	subunit of a heme lyase
KVU_1661	COG1138	Cytochrome C-type biogenesis protein
KVU_1662	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KVU_1663	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KVU_1664	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KVU_1665	COG0583	DNA-binding transcription factor activity
KVU_1666	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KVU_1667	COG0271	Belongs to the BolA IbaG family
KVU_1668	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KVU_1671	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KVU_1672	COG2354	Protein conserved in bacteria
KVU_1675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KVU_1677	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KVU_1678	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KVU_1682	COG0590	tRNA wobble adenosine to inosine editing
KVU_1683	COG1187	pseudouridine synthase activity
KVU_1690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KVU_1691	COG1490	D-aminoacyl-tRNA deacylase activity
KVU_1692	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KVU_1693	COG0037	tRNA processing
KVU_1695	COG2885	chlorophyll binding
KVU_1696	COG0823	Involved in the tonB-independent uptake of proteins
KVU_1700	COG0824	Thioesterase
KVU_1702	COG2255	four-way junction helicase activity
KVU_1703	COG0632	four-way junction helicase activity
KVU_1706	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KVU_1707	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KVU_1708	COG0124	histidyl-tRNA synthetase
KVU_1711	COG5507	3-demethylubiquinone-9 3-methyltransferase
KVU_1713	COG3895	Periplasmic Protein
KVU_1714	COG0737	Belongs to the 5'-nucleotidase family
KVU_1716	COG0167	dihydroorotate dehydrogenase activity
KVU_1721	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KVU_1722	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KVU_1723	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KVU_1725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KVU_1727	COG2267	carboxylic ester hydrolase activity
KVU_1728	COG0481	GTPase activity
KVU_1734	COG3932	Exopolysaccharide synthesis, ExoD
KVU_1735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KVU_1736	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KVU_1738	COG1464	Belongs to the NlpA lipoprotein family
KVU_1739	COG3237	CsbD-like
KVU_1741	COG1027	Aspartate ammonia-lyase
KVU_1745	COG0848	biopolymer transport protein
KVU_1747	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KVU_1750	COG1522	sequence-specific DNA binding
KVU_1751	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KVU_1751	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KVU_1751	COG0506	proline dehydrogenase activity
KVU_1753	COG0583	DNA-binding transcription factor activity
KVU_1756	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KVU_1757	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KVU_1760	COG1132	(ABC) transporter
KVU_1762	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KVU_1763	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KVU_1768	COG0625	glutathione transferase activity
KVU_1769	COG0187	DNA topoisomerase II activity
KVU_1771	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KVU_1774	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KVU_1780	COG0217	transcriptional regulatory protein
KVU_1781	COG1692	metallophosphoesterase
KVU_1783	COG2239	Acts as a magnesium transporter
KVU_1785	COG1522	sequence-specific DNA binding
KVU_1786	COG2814	Major facilitator Superfamily
KVU_1787	COG0483	inositol monophosphate 1-phosphatase activity
KVU_1788	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KVU_1792	COG0670	Belongs to the BI1 family
KVU_1797	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KVU_1801	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KVU_1802	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KVU_1803	COG1472	Belongs to the glycosyl hydrolase 3 family
KVU_1805	COG0018	arginyl-trna synthetase
KVU_1810	COG1007	ATP synthesis coupled electron transport
KVU_1813	COG0713	ATP synthesis coupled electron transport
KVU_1815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KVU_1816	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KVU_1823	COG0649	NAD binding
KVU_1825	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KVU_1827	COG0546	phosphoglycolate phosphatase activity
KVU_1828	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KVU_1833	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KVU_1835	COG4771	TonB-dependent receptor
KVU_1837	COG1464	Belongs to the NlpA lipoprotein family
KVU_1839	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KVU_1840	COG2011	ABC-type metal ion transport system permease component
KVU_1844	COG4172	Belongs to the ABC transporter superfamily
KVU_1846	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1847	COG0601	transmembrane transport
KVU_1855	COG1802	Transcriptional regulator
KVU_1858	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KVU_1859	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KVU_1860	COG1012	belongs to the aldehyde dehydrogenase family
KVU_1862	COG3008	intermembrane lipid transfer
KVU_1862	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KVU_1863	COG0131	Imidazoleglycerol-phosphate dehydratase
KVU_1864	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KVU_1865	COG0107	imidazoleglycerol-phosphate synthase activity
KVU_1866	COG0140	phosphoribosyl-ATP diphosphatase activity
KVU_1868	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KVU_1870	COG0697	spore germination
KVU_1872	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVU_1873	COG1335	isochorismatase
KVU_1874	COG0251	oxidation-reduction process
KVU_1876	COG2267	carboxylic ester hydrolase activity
KVU_1877	COG0848	biopolymer transport protein
KVU_1879	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KVU_1881	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KVU_1884	COG1957	nucleoside hydrolase
KVU_1887	COG1172	Belongs to the binding-protein-dependent transport system permease family
KVU_1889	COG2514	catechol 2,3-dioxygenase activity
KVU_1893	COG0725	ABC transporter, periplasmic molybdate-binding protein
KVU_1894	COG4149	molybdate abc transporter
KVU_1895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KVU_1902	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KVU_1903	COG0612	Peptidase, M16
KVU_1904	COG0612	Peptidase, M16
KVU_1907	COG0138	bifunctional purine biosynthesis protein purh
KVU_1912	COG0346	lactoylglutathione lyase activity
KVU_1914	COG0450	alkyl hydroperoxide reductase
KVU_1915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KVU_1917	COG0268	Binds directly to 16S ribosomal RNA
KVU_1919	COG2226	methyltransferase
KVU_1920	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KVU_1927	COG5443	negative regulation of bacterial-type flagellum assembly
KVU_1930	COG1815	bacterial-type flagellum-dependent cell motility
KVU_1931	COG1558	bacterial-type flagellum-dependent cell motility
KVU_1932	COG1677	Flagellar hook-basal body complex protein FliE
KVU_1933	COG1987	bacterial-type flagellum assembly
KVU_1934	COG4786	Flagellar basal body rod
KVU_1935	COG4786	Flagellar basal body rod
KVU_1937	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KVU_1940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KVU_1942	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KVU_1944	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KVU_1950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KVU_1951	COG1338	Plays a role in the flagellum-specific transport system
KVU_1952	COG1706	bacterial-type flagellum-dependent cell motility
KVU_1955	COG1749	Flagellar hook protein flgE
KVU_1956	COG1360	Flagellar Motor Protein
KVU_1966	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KVU_1970	COG1686	Belongs to the peptidase S11 family
KVU_1971	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KVU_1973	COG0084	hydrolase, TatD family'
KVU_1974	COG0321	lipoyl(octanoyl) transferase activity
KVU_1974	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KVU_1986	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KVU_1989	COG4166	transmembrane transport
KVU_1990	COG0601	transmembrane transport
KVU_1991	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_1992	COG4172	Belongs to the ABC transporter superfamily
KVU_1994	COG0754	glutathionylspermidine amidase activity
KVU_1995	COG5463	Belongs to the UPF0441 family
KVU_1996	COG1509	lysine 2,3-aminomutase activity
KVU_1998	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KVU_2000	COG0175	sulfate reduction
KVU_2001	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KVU_2004	COG0395	ABC-type sugar transport system, permease component
KVU_2009	COG2188	Transcriptional regulator
KVU_2024	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVU_2024	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KVU_2026	COG3781	membrane
KVU_2027	COG0535	radical SAM domain protein
KVU_2028	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KVU_2039	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KVU_2041	COG1984	allophanate hydrolase subunit 2
KVU_2048	COG0024	Methionine aminopeptidase
KVU_2049	COG2832	Protein of unknown function (DUF454)
KVU_2050	COG1733	regulation of RNA biosynthetic process
KVU_2051	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KVU_2053	COG2169	Transcriptional regulator
KVU_2053	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KVU_2056	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KVU_2057	COG0594	ribonuclease P activity
KVU_2058	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KVU_2059	COG0037	tRNA processing
KVU_2060	COG0706	membrane insertase activity
KVU_2062	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KVU_2063	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KVU_2065	COG1126	abc transporter atp-binding protein
KVU_2067	COG0765	amino acid transport
KVU_2068	COG4597	amino acid ABC transporter
KVU_2069	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KVU_2071	COG0546	phosphoglycolate phosphatase activity
KVU_2073	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KVU_2074	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KVU_2078	COG0203	ribosomal protein L17
KVU_2079	COG0202	RNA polymerase activity
KVU_2080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KVU_2081	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KVU_2082	COG0563	adenylate kinase activity
KVU_2083	COG0201	protein transport
KVU_2084	COG0200	Binds to the 23S rRNA
KVU_2085	COG1841	ribosomal large subunit assembly
KVU_2086	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KVU_2087	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KVU_2089	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KVU_2090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KVU_2091	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KVU_2092	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KVU_2095	COG0255	Belongs to the universal ribosomal protein uL29 family
KVU_2096	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KVU_2097	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KVU_2098	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KVU_2099	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KVU_2100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KVU_2101	COG0089	rRNA binding
KVU_2102	COG0088	Forms part of the polypeptide exit tunnel
KVU_2103	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KVU_2104	COG0051	transcription antitermination factor activity, RNA binding
KVU_2105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KVU_2108	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KVU_2109	COG0697	spore germination
KVU_2111	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KVU_2112	COG0085	RNA polymerase activity
KVU_2113	COG0222	ribosome binding
KVU_2114	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KVU_2115	COG0081	regulation of translation
KVU_2116	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KVU_2117	COG0250	Participates in transcription elongation, termination and antitermination
KVU_2118	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KVU_2122	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KVU_2123	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KVU_2126	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KVU_2128	COG0793	Belongs to the peptidase S41A family
KVU_2129	COG0494	nUDIX hydrolase
KVU_2130	COG0557	exoribonuclease II activity
KVU_2131	COG1028	Short-chain dehydrogenase reductase Sdr
KVU_2132	COG2951	lytic endotransglycosylase activity
KVU_2133	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KVU_2136	COG2171	N-acyltransferase activity
KVU_2138	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KVU_2147	COG0714	Associated with various cellular activities
KVU_2152	COG2309	aminopeptidase activity
KVU_2155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KVU_2156	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KVU_2157	COG1121	(ABC) transporter
KVU_2162	COG3842	ATPase activity
KVU_2163	COG0395	ABC-type sugar transport system, permease component
KVU_2164	COG1175	transmembrane transport
KVU_2166	COG0584	glycerophosphoryl diester phosphodiesterase
KVU_2169	COG1253	flavin adenine dinucleotide binding
KVU_2170	COG1247	-acetyltransferase
KVU_2172	COG1088	dTDP-glucose 4,6-dehydratase activity
KVU_2174	COG0747	negative chemotaxis
KVU_2175	COG0601	transmembrane transport
KVU_2176	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_2177	COG4172	Belongs to the ABC transporter superfamily
KVU_2178	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVU_2183	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KVU_2184	COG2350	Protein conserved in bacteria
KVU_2186	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KVU_2189	COG1137	ATPase activity
KVU_2190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KVU_2192	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KVU_2193	COG0534	Mate efflux family protein
KVU_2198	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KVU_2199	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KVU_2204	COG2003	Belongs to the UPF0758 family
KVU_2206	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KVU_2207	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KVU_2208	COG0494	nUDIX hydrolase
KVU_2209	COG1902	pentaerythritol trinitrate reductase activity
KVU_2212	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVU_2213	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KVU_2214	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KVU_2217	COG0779	Required for maturation of 30S ribosomal subunits
KVU_2222	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KVU_2223	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KVU_2224	COG1040	competence protein
KVU_2229	COG3034	peptidoglycan biosynthetic process
KVU_2231	COG0617	tRNA 3'-terminal CCA addition
KVU_2233	COG0494	nUDIX hydrolase
KVU_2235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KVU_2236	COG0137	argininosuccinate synthase activity
KVU_2239	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KVU_2240	COG1420	regulation of RNA biosynthetic process
KVU_2242	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KVU_2244	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KVU_2247	COG0445	tRNA wobble uridine modification
KVU_2248	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KVU_2249	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KVU_2250	COG0237	dephospho-CoA kinase activity
KVU_2251	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KVU_2252	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KVU_2257	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KVU_2258	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KVU_2261	COG1074	ATP-dependent DNA helicase activity
KVU_2262	COG2887	Belongs to the helicase family. UvrD subfamily
KVU_2263	COG0802	atpase or kinase
KVU_2266	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KVU_2267	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KVU_2273	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KVU_2274	COG1846	Transcriptional regulator
KVU_2275	COG0745	RESPONSE REGULATOR receiver
KVU_2276	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KVU_2278	COG0154	amidase activity
KVU_2279	COG0436	Aminotransferase
KVU_2280	COG1674	ftsk spoiiie
KVU_2286	COG3842	ATPase activity
KVU_2289	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KVU_2290	COG1609	Transcriptional regulator
KVU_2294	COG1194	a g-specific adenine glycosylase
KVU_2296	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KVU_2298	COG1663	tetraacyldisaccharide 4'-kinase activity
KVU_2299	COG1519	Transferase
KVU_2300	COG0312	modulator of DNA gyrase
KVU_2302	COG2081	HI0933 family
KVU_2303	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KVU_2308	COG0495	leucyl-tRNA aminoacylation
KVU_2313	COG0745	RESPONSE REGULATOR receiver
KVU_2315	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KVU_2318	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KVU_2320	COG4143	(ABC) transporter
KVU_2323	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KVU_2324	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KVU_2325	COG0564	pseudouridine synthase activity
KVU_2327	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KVU_2329	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KVU_2331	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KVU_2332	COG1185	polyribonucleotide nucleotidyltransferase activity
KVU_2337	COG1054	Belongs to the UPF0176 family
KVU_2338	COG1335	isochorismatase
KVU_2339	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KVU_2343	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KVU_2345	COG0514	ATP-dependent DNA helicase (RecQ)
KVU_2346	COG3022	response to hydroperoxide
KVU_2348	COG1132	(ABC) transporter
KVU_2349	COG0560	Phosphoserine phosphatase
KVU_2349	COG3830	Belongs to the UPF0237 family
KVU_2350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KVU_2351	COG0702	epimerase
KVU_2352	COG0402	S-adenosylhomocysteine deaminase activity
KVU_2353	COG1733	regulation of RNA biosynthetic process
KVU_2355	COG1253	flavin adenine dinucleotide binding
KVU_2358	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KVU_2359	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KVU_2360	COG3813	Protein conserved in bacteria
KVU_2362	COG0284	orotidine-5'-phosphate decarboxylase activity
KVU_2365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KVU_2366	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KVU_2369	COG3754	Rhamnan synthesis protein F
KVU_2371	COG1132	(ABC) transporter
KVU_2372	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KVU_2375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KVU_2376	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KVU_2376	COG1082	Xylose isomerase domain protein TIM barrel
KVU_2377	COG1802	Transcriptional regulator
KVU_2378	COG1802	Transcriptional regulator
KVU_2379	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVU_2381	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KVU_2382	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KVU_2384	COG0583	DNA-binding transcription factor activity
KVU_2385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVU_2387	COG1785	Belongs to the alkaline phosphatase family
KVU_2391	COG0714	Associated with various cellular activities
KVU_2394	COG0523	cobalamin synthesis protein
KVU_2400	COG1122	ATPase activity
KVU_2401	COG0390	transport system, permease component
KVU_2403	COG1091	dTDP-4-dehydrorhamnose reductase activity
KVU_2406	COG2072	flavoprotein involved in K transport
KVU_2412	COG4208	sulfate ABC transporter
KVU_2413	COG2897	thiosulfate sulfurtransferase activity
KVU_2414	COG2391	methyltransferase activity
KVU_2417	COG0489	protein tyrosine kinase activity
KVU_2417	COG2151	metal-sulfur cluster biosynthetic enzyme
KVU_2420	COG0513	Belongs to the DEAD box helicase family
KVU_2422	COG1742	UPF0060 membrane protein
KVU_2424	COG0335	large ribosomal subunit rRNA binding
KVU_2426	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KVU_2427	COG0228	four-way junction DNA binding
KVU_2431	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KVU_2432	COG0640	Transcriptional regulator
KVU_2435	COG0356	it plays a direct role in the translocation of protons across the membrane
KVU_2437	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KVU_2438	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KVU_2442	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KVU_2444	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KVU_2445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KVU_2446	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KVU_2449	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KVU_2454	COG0508	dehydrogenase complex catalyzes the overall conversion of
KVU_2455	COG0567	Dehydrogenase, E1 component
KVU_2457	COG0045	succinate-CoA ligase (ADP-forming) activity
KVU_2458	COG0039	L-malate dehydrogenase activity
KVU_2470	COG2188	Transcriptional regulator
KVU_2474	COG0346	lactoylglutathione lyase activity
KVU_2475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KVU_2476	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KVU_2478	COG1309	transcriptional regulator
KVU_2479	COG1764	response to oxidative stress
KVU_2485	COG4608	Belongs to the ABC transporter superfamily
KVU_2486	COG0444	Belongs to the ABC transporter superfamily
KVU_2487	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KVU_2488	COG0601	transmembrane transport
KVU_2490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVU_2491	COG0747	negative chemotaxis
KVU_2492	COG0583	DNA-binding transcription factor activity
KVU_2493	COG1802	Transcriptional regulator
KVU_2495	COG0765	amino acid transport
KVU_2496	COG1126	abc transporter atp-binding protein
KVU_2498	COG1063	alcohol dehydrogenase
KVU_2500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KVU_2501	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KVU_2502	COG2814	Major facilitator Superfamily
KVU_2503	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KVU_2504	COG0142	geranyltranstransferase activity
KVU_2505	COG1722	exodeoxyribonuclease VII activity
KVU_2506	COG2835	tetraacyldisaccharide 4'-kinase activity
KVU_2508	COG1999	signal sequence binding
KVU_2511	COG1858	cytochrome C peroxidase
KVU_2520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KVU_2526	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVU_2528	COG1132	(ABC) transporter
KVU_2531	COG1294	oxidase, subunit
KVU_2533	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KVU_2534	COG4988	ABC transporter
KVU_2536	COG2814	Major facilitator Superfamily
KVU_2537	COG0640	Transcriptional regulator
KVU_2538	COG0789	Transcriptional regulator
KVU_2542	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVU_2542	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KVU_2543	COG0521	Mo-molybdopterin cofactor biosynthetic process
KVU_2545	COG1573	uracil-dna glycosylase
KVU_2550	COG0469	pyruvate kinase activity
KVU_2552	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KVU_2553	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KVU_2554	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KVU_2555	COG0072	phenylalanine-tRNA ligase activity
KVU_2555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KVU_2556	COG0625	glutathione transferase activity
KVU_2563	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KVU_2566	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KVU_2567	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KVU_2571	COG2943	transferase activity, transferring hexosyl groups
KVU_2573	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KVU_2575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KVU_2577	COG0778	Nitroreductase
KVU_2578	COG1872	DUF167
KVU_2580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KVU_2582	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KVU_2583	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KVU_2584	COG0792	nuclease activity
KVU_2585	COG0606	chelatase, subunit chli
KVU_2588	COG0339	signal peptide processing
KVU_2589	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KVU_2590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KVU_2593	COG1079	Belongs to the binding-protein-dependent transport system permease family
KVU_2594	COG4603	Belongs to the binding-protein-dependent transport system permease family
KVU_2595	COG3845	ABC transporter
KVU_PA0030	COG0587	DNA-directed DNA polymerase activity
KVU_PA0031	COG0587	DNA-directed DNA polymerase activity
KVU_PA0044	COG1129	ABC transporter
KVU_PA0146	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KVU_PB0016	COG0587	DNA-directed DNA polymerase activity
KVU_PB0052	COG0024	Methionine aminopeptidase
KVU_PB0063	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KVU_PB0068	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KVU_PB0074	COG1175	transmembrane transport
KVU_PB0080	COG3842	ATPase activity