locus-tag	class	description
AOZ06_RS00005	COG0592	DNA-directed DNA polymerase activity
AOZ06_RS00010	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AOZ06_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOZ06_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AOZ06_RS00025	COG0187	DNA topoisomerase II activity
AOZ06_RS00050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ06_RS00065	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AOZ06_RS00080	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOZ06_RS00085	COG2186	Transcriptional regulator
AOZ06_RS00090	COG2259	Doxx family
AOZ06_RS00125	COG3764	Sortase (surface protein transpeptidase)
AOZ06_RS00155	COG0515	serine threonine protein kinase
AOZ06_RS00160	COG0768	penicillin binding
AOZ06_RS00175	COG1716	ATPase activity
AOZ06_RS00180	COG1716	ATPase activity
AOZ06_RS00210	COG1309	transcriptional regulator
AOZ06_RS00215	COG2723	6-phospho-beta-galactosidase activity
AOZ06_RS00220	COG2211	Major facilitator Superfamily
AOZ06_RS00325	COG4176	ABC-type proline glycine betaine transport system permease component
AOZ06_RS00330	COG0517	IMP dehydrogenase activity
AOZ06_RS00330	COG4175	Glycine betaine
AOZ06_RS00360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ06_RS00365	COG4638	Rieske (2fe-2S)
AOZ06_RS00375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOZ06_RS00380	COG0667	Aldo Keto reductase
AOZ06_RS00385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOZ06_RS00395	COG1131	(ABC) transporter
AOZ06_RS00405	COG1725	Transcriptional regulator
AOZ06_RS00410	COG1131	(ABC) transporter
AOZ06_RS00420	COG2226	methyltransferase
AOZ06_RS00425	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS00470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOZ06_RS00480	COG1556	Lactate utilization protein
AOZ06_RS00485	COG1139	Iron-sulfur cluster binding protein
AOZ06_RS00490	COG0247	lactate metabolic process
AOZ06_RS00495	COG3275	phosphorelay sensor kinase activity
AOZ06_RS00515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS00525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS00530	COG0425	Belongs to the sulfur carrier protein TusA family
AOZ06_RS00530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOZ06_RS00540	COG4585	Histidine kinase
AOZ06_RS00545	COG2197	response regulator
AOZ06_RS00565	COG0683	leucine binding
AOZ06_RS00580	COG1022	Amp-dependent synthetase and ligase
AOZ06_RS00605	COG0653	protein targeting
AOZ06_RS00615	COG1595	DNA-templated transcription, initiation
AOZ06_RS00625	COG1528	Iron-storage protein
AOZ06_RS00635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS00665	COG0789	Transcriptional regulator
AOZ06_RS00685	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AOZ06_RS00690	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AOZ06_RS00695	COG0714	Associated with various cellular activities
AOZ06_RS00740	COG1271	oxidase subunit
AOZ06_RS00745	COG1294	oxidase, subunit
AOZ06_RS00750	COG4988	ABC transporter
AOZ06_RS00765	COG1072	(Pantothenic acid kinase))
AOZ06_RS00770	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AOZ06_RS00795	COG1376	ErfK ybiS ycfS ynhG family protein
AOZ06_RS00805	COG2197	response regulator
AOZ06_RS00810	COG4585	Histidine kinase
AOZ06_RS00830	COG1690	Belongs to the RtcB family
AOZ06_RS00835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AOZ06_RS00845	COG0754	glutathionylspermidine amidase activity
AOZ06_RS00870	COG0579	oxidoreductase
AOZ06_RS00875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOZ06_RS00905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOZ06_RS00915	COG0546	phosphoglycolate phosphatase activity
AOZ06_RS00925	COG0463	Glycosyl transferase, family 2
AOZ06_RS00930	COG0561	phosphatase activity
AOZ06_RS00950	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOZ06_RS00985	COG1216	Glycosyl transferase, family 2
AOZ06_RS01000	COG0515	serine threonine protein kinase
AOZ06_RS01005	COG1216	Glycosyl transferase, family 2
AOZ06_RS01035	COG1063	alcohol dehydrogenase
AOZ06_RS01045	COG2234	aminopeptidase activity
AOZ06_RS01070	COG0737	Belongs to the 5'-nucleotidase family
AOZ06_RS01100	COG0142	geranyltranstransferase activity
AOZ06_RS01115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ06_RS01125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ06_RS01160	COG1216	Glycosyl transferase, family 2
AOZ06_RS01200	COG3559	Exporter of polyketide antibiotics
AOZ06_RS01205	COG1131	(ABC) transporter
AOZ06_RS01245	COG0287	Prephenate dehydrogenase
AOZ06_RS01250	COG1473	amidohydrolase
AOZ06_RS01260	COG0590	tRNA wobble adenosine to inosine editing
AOZ06_RS01315	COG0698	ribose 5-phosphate isomerase
AOZ06_RS01330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ06_RS01340	COG2304	oxidoreductase activity
AOZ06_RS01350	COG0583	DNA-binding transcription factor activity
AOZ06_RS01355	COG4608	Belongs to the ABC transporter superfamily
AOZ06_RS01370	COG0747	negative chemotaxis
AOZ06_RS01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS01380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOZ06_RS01380	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOZ06_RS01385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOZ06_RS01390	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AOZ06_RS01400	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOZ06_RS01450	COG0657	acetylesterase activity
AOZ06_RS01455	COG0431	NADPH-dependent FMN reductase
AOZ06_RS01460	COG1764	response to oxidative stress
AOZ06_RS01555	COG1051	belongs to the nudix hydrolase family
AOZ06_RS01620	COG1408	metallophosphoesterase
AOZ06_RS01630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOZ06_RS01685	COG0592	DNA-directed DNA polymerase activity
AOZ06_RS01720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOZ06_RS01735	COG0596	Alpha beta hydrolase
AOZ06_RS01745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOZ06_RS01775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ06_RS01800	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOZ06_RS01805	COG1737	Transcriptional regulator
AOZ06_RS01810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOZ06_RS01815	COG3876	Protein conserved in bacteria
AOZ06_RS01820	COG1472	Belongs to the glycosyl hydrolase 3 family
AOZ06_RS01870	COG1205	dead DEAH box helicase
AOZ06_RS01870	COG1111	helicase
AOZ06_RS01875	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AOZ06_RS01895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOZ06_RS01895	COG1754	DNA topoisomerase type I activity
AOZ06_RS01910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOZ06_RS01915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOZ06_RS02035	COG2124	cytochrome p450
AOZ06_RS02045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AOZ06_RS02070	COG3706	GGDEF domain
AOZ06_RS02095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOZ06_RS02105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOZ06_RS02120	COG1940	carbohydrate kinase activity
AOZ06_RS02130	COG0601	transmembrane transport
AOZ06_RS02135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS02165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOZ06_RS02170	COG2027	D-alanyl-D-alanine carboxypeptidase
AOZ06_RS02180	COG0037	tRNA processing
AOZ06_RS02190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOZ06_RS02200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOZ06_RS02235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOZ06_RS02240	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOZ06_RS02245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AOZ06_RS02255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOZ06_RS02265	COG1120	ATPase activity
AOZ06_RS02295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOZ06_RS02320	COG1194	a g-specific adenine glycosylase
AOZ06_RS02335	COG1609	Transcriptional regulator
AOZ06_RS02340	COG3842	ATPase activity
AOZ06_RS02350	COG1121	(ABC) transporter
AOZ06_RS02355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOZ06_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS02395	COG0215	cysteine-tRNA ligase activity
AOZ06_RS02410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOZ06_RS02415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOZ06_RS02420	COG1329	Transcriptional regulator
AOZ06_RS02425	COG2847	Copper chaperone PCu(A)C
AOZ06_RS02430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOZ06_RS02440	COG1595	DNA-templated transcription, initiation
AOZ06_RS02450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOZ06_RS02470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOZ06_RS02475	COG0243	molybdopterin cofactor binding
AOZ06_RS02490	COG4399	Belongs to the UPF0754 family
AOZ06_RS02505	COG0667	Aldo Keto reductase
AOZ06_RS02510	COG0456	acetyltransferase
AOZ06_RS02515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOZ06_RS02520	COG1917	Cupin 2, conserved barrel domain protein
AOZ06_RS02525	COG5285	phytanoyl-CoA dioxygenase
AOZ06_RS02530	COG3903	Transcriptional regulator
AOZ06_RS02530	COG3629	intracellular signal transduction
AOZ06_RS02570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOZ06_RS02575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOZ06_RS02580	COG2188	Transcriptional regulator
AOZ06_RS02600	COG0352	thiamine-phosphate diphosphorylase activity
AOZ06_RS02605	COG2022	thiamine diphosphate biosynthetic process
AOZ06_RS02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOZ06_RS02615	COG2022	thiamine diphosphate biosynthetic process
AOZ06_RS02635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOZ06_RS02640	COG0351	phosphomethylpyrimidine kinase
AOZ06_RS02645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AOZ06_RS02655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS02685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOZ06_RS02690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOZ06_RS02695	COG2814	Major facilitator Superfamily
AOZ06_RS02715	COG0688	phosphatidylethanolamine metabolic process
AOZ06_RS02735	COG0459	protein refolding
AOZ06_RS02740	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS02745	COG1309	transcriptional regulator
AOZ06_RS02850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ06_RS02855	COG1116	anion transmembrane transporter activity
AOZ06_RS02860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS02870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOZ06_RS02880	COG2018	Roadblock/LC7 domain
AOZ06_RS02935	COG1388	LysM domain
AOZ06_RS02945	COG2267	carboxylic ester hydrolase activity
AOZ06_RS02950	COG1309	transcriptional regulator
AOZ06_RS02955	COG0477	Major facilitator Superfamily
AOZ06_RS02960	COG1846	Transcriptional regulator
AOZ06_RS02965	COG3585	molybdate ion transport
AOZ06_RS02990	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS03015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOZ06_RS03025	COG0546	phosphoglycolate phosphatase activity
AOZ06_RS03035	COG1278	Cold shock
AOZ06_RS03045	COG2814	Major facilitator Superfamily
AOZ06_RS03075	COG2252	PERMEase
AOZ06_RS03085	COG2814	Major facilitator Superfamily
AOZ06_RS03105	COG5398	heme oxygenase
AOZ06_RS03120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ06_RS03170	COG3237	CsbD-like
AOZ06_RS03175	COG1132	(ABC) transporter
AOZ06_RS03180	COG1132	(ABC) transporter
AOZ06_RS03205	COG2205	protein histidine kinase activity
AOZ06_RS03210	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS03225	COG0577	efflux transmembrane transporter activity
AOZ06_RS03225	COG1136	(ABC) transporter
AOZ06_RS03230	COG0577	efflux transmembrane transporter activity
AOZ06_RS03235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS03255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AOZ06_RS03260	COG2197	response regulator
AOZ06_RS03265	COG4585	Histidine kinase
AOZ06_RS03270	COG0842	Transport permease protein
AOZ06_RS03275	COG1131	(ABC) transporter
AOZ06_RS03295	COG0831	urea catabolic process
AOZ06_RS03300	COG0832	Belongs to the urease beta subunit family
AOZ06_RS03305	COG0804	urea catabolic process
AOZ06_RS03315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AOZ06_RS03320	COG0829	nickel cation binding
AOZ06_RS03325	COG0259	pyridoxamine-phosphate oxidase activity
AOZ06_RS03330	COG0477	Major facilitator Superfamily
AOZ06_RS03335	COG0531	amino acid
AOZ06_RS03345	COG1309	transcriptional regulator
AOZ06_RS03355	COG2017	converts alpha-aldose to the beta-anomer
AOZ06_RS03385	COG1228	amidohydrolase
AOZ06_RS03390	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS03395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS03405	COG0415	Belongs to the DNA photolyase family
AOZ06_RS03410	COG1668	transmembrane transport
AOZ06_RS03415	COG4152	abc transporter atp-binding protein
AOZ06_RS03430	COG0277	FAD linked oxidase domain protein
AOZ06_RS03455	COG1733	regulation of RNA biosynthetic process
AOZ06_RS03460	COG0702	epimerase
AOZ06_RS03485	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS03495	COG1169	isochorismate synthase
AOZ06_RS03535	COG0252	asparaginase activity
AOZ06_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS03550	COG1131	(ABC) transporter
AOZ06_RS03560	COG4585	Histidine kinase
AOZ06_RS03565	COG2197	response regulator
AOZ06_RS03570	COG2186	Transcriptional regulator
AOZ06_RS03575	COG0747	negative chemotaxis
AOZ06_RS03585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS03590	COG0444	Belongs to the ABC transporter superfamily
AOZ06_RS03600	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS03610	COG0154	amidase activity
AOZ06_RS03620	COG4585	Histidine kinase
AOZ06_RS03625	COG2197	response regulator
AOZ06_RS03645	COG4585	Histidine kinase
AOZ06_RS03650	COG2197	response regulator
AOZ06_RS03660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOZ06_RS03680	COG3629	intracellular signal transduction
AOZ06_RS03680	COG3903	Transcriptional regulator
AOZ06_RS03690	COG1609	Transcriptional regulator
AOZ06_RS03700	COG2183	response to ionizing radiation
AOZ06_RS03705	COG1073	alpha beta
AOZ06_RS03710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS03740	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS03760	COG1660	Displays ATPase and GTPase activities
AOZ06_RS03805	COG0477	Major facilitator Superfamily
AOZ06_RS03830	COG0789	Transcriptional regulator
AOZ06_RS03840	COG0477	Major facilitator Superfamily
AOZ06_RS03845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOZ06_RS03880	COG0477	Major facilitator Superfamily
AOZ06_RS03930	COG1657	PFAM Prenyltransferase squalene oxidase
AOZ06_RS03945	COG5002	protein histidine kinase activity
AOZ06_RS03950	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS04040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOZ06_RS04070	COG2963	transposase activity
AOZ06_RS04145	COG1132	(ABC) transporter
AOZ06_RS04190	COG4974	Belongs to the 'phage' integrase family
AOZ06_RS04320	COG3842	ATPase activity
AOZ06_RS04365	COG2815	serine threonine protein kinase
AOZ06_RS04365	COG0515	serine threonine protein kinase
AOZ06_RS04385	COG1222	aaa ATPase
AOZ06_RS04390	COG0025	NhaP-type Na H and K H
AOZ06_RS04410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS04410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS04605	COG1595	DNA-templated transcription, initiation
AOZ06_RS04655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOZ06_RS04680	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOZ06_RS04780	COG3706	GGDEF domain
AOZ06_RS04800	COG4974	Belongs to the 'phage' integrase family
AOZ06_RS04835	COG3629	intracellular signal transduction
AOZ06_RS04835	COG3903	Transcriptional regulator
AOZ06_RS04880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS04950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOZ06_RS04990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOZ06_RS05025	COG3883	PFAM NLP P60 protein
AOZ06_RS05025	COG0791	NLP P60 protein
AOZ06_RS05060	COG3903	Transcriptional regulator
AOZ06_RS05060	COG3629	intracellular signal transduction
AOZ06_RS05065	COG3706	GGDEF domain
AOZ06_RS05075	COG2124	cytochrome p450
AOZ06_RS05125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOZ06_RS05175	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOZ06_RS05190	COG3706	GGDEF domain
AOZ06_RS05295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOZ06_RS05350	COG2197	response regulator
AOZ06_RS05360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOZ06_RS05365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOZ06_RS05370	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOZ06_RS05395	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS05415	COG1522	sequence-specific DNA binding
AOZ06_RS05420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ06_RS05440	COG3345	alpha-galactosidase
AOZ06_RS05445	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS05455	COG1653	transport
AOZ06_RS05460	COG1349	DNA-binding transcription factor activity
AOZ06_RS05470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOZ06_RS05505	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS05510	COG5002	protein histidine kinase activity
AOZ06_RS05515	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOZ06_RS05515	COG0315	cyclic pyranopterin monophosphate synthase activity
AOZ06_RS05550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOZ06_RS05555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOZ06_RS05565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ06_RS05615	COG1674	ftsk spoiiie
AOZ06_RS05640	COG2367	Beta-lactamase
AOZ06_RS05650	COG1309	transcriptional regulator
AOZ06_RS05670	COG5002	protein histidine kinase activity
AOZ06_RS05675	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS05690	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS05710	COG0515	serine threonine protein kinase
AOZ06_RS05730	COG1162	GTPase activity
AOZ06_RS05735	COG0842	Transport permease protein
AOZ06_RS05750	COG0084	hydrolase, TatD family'
AOZ06_RS05755	COG3583	domain protein
AOZ06_RS05760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOZ06_RS05765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOZ06_RS05770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOZ06_RS05775	COG0488	(ABC) transporter
AOZ06_RS05780	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS05785	COG2319	Wd-40 repeat
AOZ06_RS05785	COG5635	Nacht domain
AOZ06_RS05790	COG0193	aminoacyl-tRNA hydrolase activity
AOZ06_RS05820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOZ06_RS05840	COG1309	transcriptional regulator
AOZ06_RS05860	COG2133	pyrroloquinoline quinone binding
AOZ06_RS05865	COG1024	Enoyl-CoA hydratase
AOZ06_RS05900	COG4946	Tricorn protease homolog
AOZ06_RS05900	COG0793	Belongs to the peptidase S41A family
AOZ06_RS05935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOZ06_RS05950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOZ06_RS05965	COG0148	phosphopyruvate hydratase activity
AOZ06_RS05990	COG0747	negative chemotaxis
AOZ06_RS05995	COG0601	transmembrane transport
AOZ06_RS06000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS06010	COG4608	Belongs to the ABC transporter superfamily
AOZ06_RS06050	COG0714	Associated with various cellular activities
AOZ06_RS06085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOZ06_RS06105	COG0789	Transcriptional regulator
AOZ06_RS06120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOZ06_RS06155	COG1595	DNA-templated transcription, initiation
AOZ06_RS06185	COG0183	Belongs to the thiolase family
AOZ06_RS06190	COG2755	lipolytic protein G-D-S-L family
AOZ06_RS06200	COG1473	amidohydrolase
AOZ06_RS06245	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AOZ06_RS06260	COG1522	sequence-specific DNA binding
AOZ06_RS06265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOZ06_RS06275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOZ06_RS06285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOZ06_RS06295	COG1331	Highly conserved protein containing a thioredoxin domain
AOZ06_RS06350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOZ06_RS06355	COG1793	dna ligase
AOZ06_RS06375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS06390	COG0114	fumarate hydratase activity
AOZ06_RS06395	COG0492	ferredoxin-NADP+ reductase activity
AOZ06_RS06405	COG3467	pyridoxamine 5'-phosphate
AOZ06_RS06445	COG1722	exodeoxyribonuclease VII activity
AOZ06_RS06455	COG1570	exodeoxyribonuclease VII activity
AOZ06_RS06465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOZ06_RS06480	COG0420	3'-5' exonuclease activity
AOZ06_RS06485	COG0419	ATPase involved in DNA repair
AOZ06_RS06490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOZ06_RS06490	COG2169	Transcriptional regulator
AOZ06_RS06500	COG0012	GTP binding
AOZ06_RS06510	COG2234	aminopeptidase activity
AOZ06_RS06515	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOZ06_RS06530	COG3842	ATPase activity
AOZ06_RS06540	COG1131	(ABC) transporter
AOZ06_RS06550	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS06570	COG1309	transcriptional regulator
AOZ06_RS06580	COG0180	Tryptophanyl-tRNA synthetase
AOZ06_RS06595	COG1217	gtp-binding protein TYPA
AOZ06_RS06605	COG0747	negative chemotaxis
AOZ06_RS06615	COG0601	transmembrane transport
AOZ06_RS06630	COG4608	Belongs to the ABC transporter superfamily
AOZ06_RS06635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOZ06_RS06690	COG1611	Belongs to the LOG family
AOZ06_RS06705	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS06705	COG0204	Acyl-transferase
AOZ06_RS06710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOZ06_RS06715	COG0463	Glycosyl transferase, family 2
AOZ06_RS06730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOZ06_RS06755	COG0535	radical SAM domain protein
AOZ06_RS06780	COG2818	Glycosylase
AOZ06_RS06785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOZ06_RS06790	COG0583	DNA-binding transcription factor activity
AOZ06_RS06795	COG2814	Major facilitator Superfamily
AOZ06_RS06800	COG0297	glycogen (starch) synthase activity
AOZ06_RS06805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOZ06_RS06815	COG4122	O-methyltransferase activity
AOZ06_RS06830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOZ06_RS06835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOZ06_RS06865	COG2239	Acts as a magnesium transporter
AOZ06_RS06965	COG0598	Magnesium transport protein CorA
AOZ06_RS06980	COG0406	alpha-ribazole phosphatase activity
AOZ06_RS06980	COG0494	nUDIX hydrolase
AOZ06_RS07005	COG2095	MarC family integral membrane protein
AOZ06_RS07020	COG0702	epimerase
AOZ06_RS07050	COG0513	Belongs to the DEAD box helicase family
AOZ06_RS07085	COG1309	transcriptional regulator
AOZ06_RS07090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ06_RS07090	COG0596	Alpha beta hydrolase
AOZ06_RS07120	COG0243	molybdopterin cofactor binding
AOZ06_RS07125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ06_RS07130	COG2223	nitrite transmembrane transporter activity
AOZ06_RS07135	COG2146	nitrite reductase [NAD(P)H] activity
AOZ06_RS07135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ06_RS07170	COG2197	response regulator
AOZ06_RS07175	COG0596	Alpha beta hydrolase
AOZ06_RS07185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOZ06_RS07200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOZ06_RS07205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOZ06_RS07245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOZ06_RS07245	COG0475	glutathione-regulated potassium exporter activity
AOZ06_RS07250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOZ06_RS07280	COG0612	Peptidase, M16
AOZ06_RS07295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOZ06_RS07335	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AOZ06_RS07355	COG3001	Fructosamine kinase
AOZ06_RS07370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOZ06_RS07385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS07405	COG0431	NADPH-dependent FMN reductase
AOZ06_RS07415	COG1733	regulation of RNA biosynthetic process
AOZ06_RS07480	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS07485	COG3795	YCII-related domain
AOZ06_RS07495	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AOZ06_RS07505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOZ06_RS07515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOZ06_RS07520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOZ06_RS07520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOZ06_RS07545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOZ06_RS07545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOZ06_RS07550	COG0653	protein targeting
AOZ06_RS07575	COG0477	Major facilitator Superfamily
AOZ06_RS07585	COG4977	sequence-specific DNA binding
AOZ06_RS07695	COG2197	response regulator
AOZ06_RS07935	COG0174	glutamine synthetase
AOZ06_RS07945	COG1595	DNA-templated transcription, initiation
AOZ06_RS07995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOZ06_RS08020	COG4585	Histidine kinase
AOZ06_RS08070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOZ06_RS08090	COG3480	Lon protease (S16) C-terminal proteolytic domain
AOZ06_RS08100	COG1615	UPF0182 protein
AOZ06_RS08110	COG4977	sequence-specific DNA binding
AOZ06_RS08130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOZ06_RS08135	COG2884	Cell division ATP-binding protein ftsE
AOZ06_RS08140	COG2177	Part of the ABC transporter FtsEX involved in
AOZ06_RS08145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AOZ06_RS08170	COG0604	alcohol dehydrogenase
AOZ06_RS08185	COG0789	Transcriptional regulator
AOZ06_RS08235	COG1643	Atp-dependent helicase
AOZ06_RS08250	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AOZ06_RS08335	COG0823	Involved in the tonB-independent uptake of proteins
AOZ06_RS08335	COG4946	Tricorn protease homolog
AOZ06_RS08335	COG1506	peptidase
AOZ06_RS08345	COG4974	Belongs to the 'phage' integrase family
AOZ06_RS08350	COG0270	DNA (cytosine-5-)-methyltransferase activity
AOZ06_RS08475	COG1857	crispr-associated protein
AOZ06_RS08560	COG0693	protein deglycase activity
AOZ06_RS08560	COG0753	catalase activity
AOZ06_RS08575	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS08630	COG0596	Alpha beta hydrolase
AOZ06_RS08635	COG2770	Histidine kinase
AOZ06_RS08635	COG2208	phosphoserine phosphatase activity
AOZ06_RS08680	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOZ06_RS08685	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AOZ06_RS08695	COG2205	protein histidine kinase activity
AOZ06_RS08715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOZ06_RS08720	COG1335	isochorismatase
AOZ06_RS08735	COG0076	glutamate decarboxylase activity
AOZ06_RS08740	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOZ06_RS08740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOZ06_RS08790	COG0183	Belongs to the thiolase family
AOZ06_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS08810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ06_RS08815	COG0028	Belongs to the TPP enzyme family
AOZ06_RS08825	COG1309	transcriptional regulator
AOZ06_RS08840	COG1404	Belongs to the peptidase S8 family
AOZ06_RS08860	COG0488	(ABC) transporter
AOZ06_RS08875	COG0515	serine threonine protein kinase
AOZ06_RS08875	COG2815	serine threonine protein kinase
AOZ06_RS08885	COG0714	Associated with various cellular activities
AOZ06_RS08920	COG0542	response to heat
AOZ06_RS08935	COG2391	methyltransferase activity
AOZ06_RS08990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOZ06_RS08995	COG0326	Molecular chaperone. Has ATPase activity
AOZ06_RS09045	COG2255	four-way junction helicase activity
AOZ06_RS09060	COG3629	intracellular signal transduction
AOZ06_RS09060	COG3903	Transcriptional regulator
AOZ06_RS09080	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS09095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOZ06_RS09115	COG3285	dna ligase
AOZ06_RS09115	COG1793	dna ligase
AOZ06_RS09120	COG0673	inositol 2-dehydrogenase activity
AOZ06_RS09125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOZ06_RS09130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOZ06_RS09170	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS09175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS09210	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS09210	COG1672	PFAM Archaeal ATPase
AOZ06_RS09230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS09275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS09305	COG5001	Diguanylate cyclase
AOZ06_RS09305	COG3300	MHYT domain
AOZ06_RS09315	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AOZ06_RS09320	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AOZ06_RS09335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOZ06_RS09340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS09345	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS09350	COG2814	Major facilitator Superfamily
AOZ06_RS09355	COG0154	amidase activity
AOZ06_RS09380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOZ06_RS09410	COG3938	Belongs to the proline racemase family
AOZ06_RS09415	COG1122	ATPase activity
AOZ06_RS09430	COG0310	cobalt ion transport
AOZ06_RS09445	COG1309	transcriptional regulator
AOZ06_RS09455	COG0183	Belongs to the thiolase family
AOZ06_RS09475	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS09475	COG2030	dehydratase
AOZ06_RS09480	COG3396	Phenylacetate-CoA oxygenase
AOZ06_RS09485	COG3460	Phenylacetate-CoA oxygenase
AOZ06_RS09490	COG3396	Phenylacetate-CoA oxygenase
AOZ06_RS09495	COG2151	metal-sulfur cluster biosynthetic enzyme
AOZ06_RS09500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOZ06_RS09515	COG3706	GGDEF domain
AOZ06_RS09530	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS09535	COG0823	Involved in the tonB-independent uptake of proteins
AOZ06_RS09540	COG1063	alcohol dehydrogenase
AOZ06_RS09545	COG0156	8-amino-7-oxononanoate synthase activity
AOZ06_RS09560	COG0477	Major facilitator Superfamily
AOZ06_RS09565	COG0406	alpha-ribazole phosphatase activity
AOZ06_RS09570	COG2197	response regulator
AOZ06_RS09575	COG4585	Histidine kinase
AOZ06_RS09585	COG0542	response to heat
AOZ06_RS09620	COG2197	response regulator
AOZ06_RS09660	COG1131	(ABC) transporter
AOZ06_RS09690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOZ06_RS09735	COG1335	isochorismatase
AOZ06_RS09740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOZ06_RS09745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOZ06_RS09755	COG3191	aminopeptidase activity
AOZ06_RS09775	COG3386	PFAM SMP-30 Gluconolaconase
AOZ06_RS09780	COG0705	Rhomboid family
AOZ06_RS09790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOZ06_RS09795	COG1234	tRNA 3'-trailer cleavage
AOZ06_RS09800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AOZ06_RS09890	COG1309	transcriptional regulator
AOZ06_RS09905	COG1316	TRANSCRIPTIONal
AOZ06_RS09915	COG3629	intracellular signal transduction
AOZ06_RS09915	COG3903	Transcriptional regulator
AOZ06_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS09970	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ06_RS09985	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOZ06_RS09990	COG0488	(ABC) transporter
AOZ06_RS10000	COG1672	PFAM Archaeal ATPase
AOZ06_RS10000	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS10020	COG4585	Histidine kinase
AOZ06_RS10030	COG1403	HNH endonuclease
AOZ06_RS10065	COG1349	DNA-binding transcription factor activity
AOZ06_RS10085	COG2197	response regulator
AOZ06_RS10165	COG1472	Belongs to the glycosyl hydrolase 3 family
AOZ06_RS10175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOZ06_RS10180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOZ06_RS10185	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS10200	COG1793	dna ligase
AOZ06_RS10215	COG2608	mercury ion transmembrane transporter activity
AOZ06_RS10225	COG1316	TRANSCRIPTIONal
AOZ06_RS10230	COG0726	polysaccharide deacetylase
AOZ06_RS10240	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS10245	COG2205	protein histidine kinase activity
AOZ06_RS10270	COG2267	carboxylic ester hydrolase activity
AOZ06_RS10285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOZ06_RS10300	COG2124	cytochrome p450
AOZ06_RS10325	COG1116	anion transmembrane transporter activity
AOZ06_RS10330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS10340	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS10340	COG3848	Pyruvate phosphate dikinase
AOZ06_RS10345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOZ06_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS10390	COG0529	Catalyzes the synthesis of activated sulfate
AOZ06_RS10410	COG4977	sequence-specific DNA binding
AOZ06_RS10425	COG1136	(ABC) transporter
AOZ06_RS10460	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS10470	COG1376	ErfK ybiS ycfS ynhG family protein
AOZ06_RS10490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOZ06_RS10495	COG0433	COG0433 Predicted ATPase
AOZ06_RS10505	COG2124	cytochrome p450
AOZ06_RS10540	COG2814	Major facilitator Superfamily
AOZ06_RS10545	COG1846	Transcriptional regulator
AOZ06_RS10550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOZ06_RS10600	COG3639	organic phosphonate transmembrane transporter activity
AOZ06_RS10605	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AOZ06_RS10615	COG3573	Dehydrogenase
AOZ06_RS10620	COG2188	Transcriptional regulator
AOZ06_RS10635	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS10655	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS10695	COG3835	regulator
AOZ06_RS10710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOZ06_RS10725	COG4251	negative regulation of phosphorylation
AOZ06_RS10725	COG2203	Gaf domain
AOZ06_RS10725	COG3706	GGDEF domain
AOZ06_RS10725	COG5001	Diguanylate cyclase
AOZ06_RS10735	COG0492	ferredoxin-NADP+ reductase activity
AOZ06_RS10750	COG0076	glutamate decarboxylase activity
AOZ06_RS10805	COG1609	Transcriptional regulator
AOZ06_RS10810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS10820	COG1116	anion transmembrane transporter activity
AOZ06_RS10840	COG0386	Belongs to the glutathione peroxidase family
AOZ06_RS10845	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS10930	COG0673	inositol 2-dehydrogenase activity
AOZ06_RS10940	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS11020	COG4221	oxidoreductase activity
AOZ06_RS11025	COG2267	carboxylic ester hydrolase activity
AOZ06_RS11055	COG2188	Transcriptional regulator
AOZ06_RS11070	COG1609	Transcriptional regulator
AOZ06_RS11075	COG0583	DNA-binding transcription factor activity
AOZ06_RS11080	COG2814	Major facilitator Superfamily
AOZ06_RS11085	COG2267	carboxylic ester hydrolase activity
AOZ06_RS11090	COG1309	transcriptional regulator
AOZ06_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS11115	COG0714	Associated with various cellular activities
AOZ06_RS11120	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AOZ06_RS11140	COG1609	Transcriptional regulator
AOZ06_RS11170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOZ06_RS11175	COG1309	transcriptional regulator
AOZ06_RS11220	COG0583	DNA-binding transcription factor activity
AOZ06_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS11245	COG3336	cytochrome c oxidase
AOZ06_RS11265	COG2902	Dehydrogenase
AOZ06_RS11285	COG0366	Alpha amylase catalytic
AOZ06_RS11295	COG0668	transmembrane transport
AOZ06_RS11310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AOZ06_RS11320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOZ06_RS11340	COG0698	ribose 5-phosphate isomerase
AOZ06_RS11360	COG4552	Acetyltransferase involved in intracellular survival and related
AOZ06_RS11460	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOZ06_RS11465	COG0740	serine-type endopeptidase activity
AOZ06_RS11470	COG0740	serine-type endopeptidase activity
AOZ06_RS11475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOZ06_RS11485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOZ06_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS11535	COG0577	efflux transmembrane transporter activity
AOZ06_RS11535	COG1136	(ABC) transporter
AOZ06_RS11540	COG0577	efflux transmembrane transporter activity
AOZ06_RS11540	COG1136	(ABC) transporter
AOZ06_RS11550	COG0525	valine-tRNA ligase activity
AOZ06_RS11575	COG2205	protein histidine kinase activity
AOZ06_RS11580	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS11600	COG0285	dihydrofolate synthase activity
AOZ06_RS11615	COG0105	UTP biosynthetic process
AOZ06_RS11625	COG1131	(ABC) transporter
AOZ06_RS11645	COG1131	(ABC) transporter
AOZ06_RS11650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS11675	COG1530	ribonuclease E activity
AOZ06_RS11675	COG1530	ribonuclease E activity
AOZ06_RS11680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOZ06_RS11685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AOZ06_RS11690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOZ06_RS11700	COG0477	Major facilitator Superfamily
AOZ06_RS11730	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AOZ06_RS11730	COG0778	Nitroreductase
AOZ06_RS11735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOZ06_RS11740	COG0799	negative regulation of ribosome biogenesis
AOZ06_RS11745	COG0406	alpha-ribazole phosphatase activity
AOZ06_RS11750	COG2755	lipolytic protein G-D-S-L family
AOZ06_RS11755	COG1307	EDD domain protein, DegV family
AOZ06_RS11760	COG1596	polysaccharide export
AOZ06_RS11760	COG1555	photosystem II stabilization
AOZ06_RS11770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS11780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOZ06_RS11800	COG0268	Binds directly to 16S ribosomal RNA
AOZ06_RS11835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOZ06_RS11875	COG0604	alcohol dehydrogenase
AOZ06_RS11910	COG1024	Enoyl-CoA hydratase
AOZ06_RS11925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS11950	COG0175	sulfate reduction
AOZ06_RS11960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOZ06_RS11970	COG1309	transcriptional regulator
AOZ06_RS11985	COG1620	l-lactate permease
AOZ06_RS11990	COG1414	Transcriptional regulator
AOZ06_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS12005	COG2856	Zn peptidase
AOZ06_RS12020	COG0484	heat shock protein binding
AOZ06_RS12030	COG2197	response regulator
AOZ06_RS12050	COG0537	adenosine 5'-monophosphoramidase activity
AOZ06_RS12060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOZ06_RS12075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOZ06_RS12090	COG1381	Involved in DNA repair and RecF pathway recombination
AOZ06_RS12100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOZ06_RS12110	COG0701	Predicted permease
AOZ06_RS12140	COG0423	glycine-tRNA ligase activity
AOZ06_RS12165	COG1131	(ABC) transporter
AOZ06_RS12175	COG4585	Histidine kinase
AOZ06_RS12180	COG2197	response regulator
AOZ06_RS12190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOZ06_RS12205	COG1595	DNA-templated transcription, initiation
AOZ06_RS12210	COG0358	DNA primase activity
AOZ06_RS12220	COG4106	trans-aconitate 2-methyltransferase activity
AOZ06_RS12255	COG0626	cystathionine gamma-synthase activity
AOZ06_RS12300	COG0187	DNA topoisomerase II activity
AOZ06_RS12305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOZ06_RS12340	COG1070	Carbohydrate kinase
AOZ06_RS12360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOZ06_RS12380	COG0028	Belongs to the TPP enzyme family
AOZ06_RS12390	COG0765	amino acid transport
AOZ06_RS12395	COG1126	abc transporter atp-binding protein
AOZ06_RS12400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS12410	COG0277	FAD linked oxidase domain protein
AOZ06_RS12480	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AOZ06_RS12490	COG1335	isochorismatase
AOZ06_RS12495	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS12500	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS12505	COG3845	ABC transporter
AOZ06_RS12520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOZ06_RS12525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ06_RS12540	COG1252	NADH dehydrogenase
AOZ06_RS12545	COG3201	nicotinamide mononucleotide transporter
AOZ06_RS12875	COG4974	Belongs to the 'phage' integrase family
AOZ06_RS13195	COG4974	Belongs to the 'phage' integrase family
AOZ06_RS13215	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOZ06_RS13220	COG0477	Major facilitator Superfamily
AOZ06_RS13230	COG2197	response regulator
AOZ06_RS13235	COG0443	Heat shock 70 kDa protein
AOZ06_RS13280	COG1404	Belongs to the peptidase S8 family
AOZ06_RS13280	COG4412	M6 family metalloprotease domain protein
AOZ06_RS13295	COG0586	Pfam SNARE associated Golgi protein
AOZ06_RS13300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOZ06_RS13315	COG2866	Carboxypeptidase
AOZ06_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS13340	COG1090	epimerase
AOZ06_RS13350	COG0321	lipoyl(octanoyl) transferase activity
AOZ06_RS13360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOZ06_RS13365	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ06_RS13380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOZ06_RS13390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOZ06_RS13420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AOZ06_RS13430	COG0667	Aldo Keto reductase
AOZ06_RS13450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS13455	COG3608	succinylglutamate desuccinylase aspartoacylase
AOZ06_RS13455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AOZ06_RS13470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOZ06_RS13480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOZ06_RS13490	COG1845	cytochrome c oxidase, subunit III
AOZ06_RS13495	COG2010	Cytochrome c
AOZ06_RS13505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOZ06_RS13510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOZ06_RS13520	COG0662	Cupin 2, conserved barrel domain protein
AOZ06_RS13550	COG3345	alpha-galactosidase
AOZ06_RS13555	COG0366	Alpha amylase catalytic
AOZ06_RS13560	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS13565	COG1175	transmembrane transport
AOZ06_RS13580	COG1876	peptidase activity
AOZ06_RS13585	COG3973	AAA domain
AOZ06_RS13605	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS13610	COG1940	carbohydrate kinase activity
AOZ06_RS13695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOZ06_RS13695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOZ06_RS13700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOZ06_RS13710	COG1846	Transcriptional regulator
AOZ06_RS13715	COG0697	spore germination
AOZ06_RS13750	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOZ06_RS13755	COG2815	serine threonine protein kinase
AOZ06_RS13755	COG0515	serine threonine protein kinase
AOZ06_RS13780	COG0142	geranyltranstransferase activity
AOZ06_RS13800	COG1309	transcriptional regulator
AOZ06_RS13805	COG0667	Aldo Keto reductase
AOZ06_RS13840	COG2807	transmembrane transport
AOZ06_RS13845	COG0242	peptide deformylase activity
AOZ06_RS13870	COG0302	gtp cyclohydrolase
AOZ06_RS13880	COG3250	beta-galactosidase activity
AOZ06_RS13905	COG1201	RNA secondary structure unwinding
AOZ06_RS13910	COG2197	response regulator
AOZ06_RS13915	COG4585	Histidine kinase
AOZ06_RS13940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ06_RS13945	COG1349	DNA-binding transcription factor activity
AOZ06_RS13950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOZ06_RS13960	COG0443	Heat shock 70 kDa protein
AOZ06_RS13980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOZ06_RS13985	COG2137	regulation of response to DNA damage stimulus
AOZ06_RS13990	COG0800	Aldolase
AOZ06_RS14035	COG0765	amino acid transport
AOZ06_RS14040	COG0765	amino acid transport
AOZ06_RS14050	COG1126	abc transporter atp-binding protein
AOZ06_RS14055	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS14060	COG0642	Histidine kinase
AOZ06_RS14070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOZ06_RS14130	COG1196	nuclear chromosome segregation
AOZ06_RS14140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOZ06_RS14155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOZ06_RS14165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOZ06_RS14170	COG1388	LysM domain
AOZ06_RS14175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOZ06_RS14180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOZ06_RS14185	COG1595	DNA-templated transcription, initiation
AOZ06_RS14190	COG1846	Transcriptional regulator
AOZ06_RS14215	COG3795	YCII-related domain
AOZ06_RS14225	COG2124	cytochrome p450
AOZ06_RS14240	COG2321	neutral zinc metallopeptidase
AOZ06_RS14245	COG1505	serine-type exopeptidase activity
AOZ06_RS14260	COG0517	IMP dehydrogenase activity
AOZ06_RS14260	COG0516	GMP reductase activity
AOZ06_RS14295	COG2304	oxidoreductase activity
AOZ06_RS14300	COG0631	protein serine/threonine phosphatase activity
AOZ06_RS14315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS14325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOZ06_RS14335	COG2936	dipeptidyl-peptidase activity
AOZ06_RS14345	COG3345	alpha-galactosidase
AOZ06_RS14365	COG1940	carbohydrate kinase activity
AOZ06_RS14365	COG1846	Transcriptional regulator
AOZ06_RS14385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOZ06_RS14390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOZ06_RS14410	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOZ06_RS14425	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOZ06_RS14430	COG1215	transferase activity, transferring glycosyl groups
AOZ06_RS14435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOZ06_RS14440	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS14445	COG2205	protein histidine kinase activity
AOZ06_RS14470	COG1653	transport
AOZ06_RS14475	COG1175	transmembrane transport
AOZ06_RS14485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOZ06_RS14490	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS14510	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
AOZ06_RS14525	COG1490	D-aminoacyl-tRNA deacylase activity
AOZ06_RS14545	COG2313	pseudouridylate synthase activity
AOZ06_RS14560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOZ06_RS14580	COG4213	ABC transporter substrate-binding protein
AOZ06_RS14590	COG4214	carbohydrate transport
AOZ06_RS14595	COG1940	carbohydrate kinase activity
AOZ06_RS14620	COG0483	inositol monophosphate 1-phosphatase activity
AOZ06_RS14640	COG0756	dUTP diphosphatase activity
AOZ06_RS14690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ06_RS14700	COG0569	domain protein
AOZ06_RS14705	COG0531	amino acid
AOZ06_RS14710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOZ06_RS14715	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS14730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOZ06_RS14735	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS14740	COG2205	protein histidine kinase activity
AOZ06_RS14765	COG0515	serine threonine protein kinase
AOZ06_RS14780	COG1024	Enoyl-CoA hydratase
AOZ06_RS14780	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ06_RS14785	COG0183	Belongs to the thiolase family
AOZ06_RS14815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOZ06_RS14820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOZ06_RS14845	COG3253	May function as heme-dependent peroxidase
AOZ06_RS14865	COG1404	Belongs to the peptidase S8 family
AOZ06_RS14880	COG3220	belongs to the UPF0276 family
AOZ06_RS14900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOZ06_RS14910	COG0124	histidyl-tRNA synthetase
AOZ06_RS14940	COG4106	trans-aconitate 2-methyltransferase activity
AOZ06_RS14945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOZ06_RS14945	COG1796	DNA polymerase
AOZ06_RS14970	COG5006	permease, DMT superfamily
AOZ06_RS14985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS14990	COG1793	dna ligase
AOZ06_RS15050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOZ06_RS15055	COG2326	polyphosphate kinase activity
AOZ06_RS15065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOZ06_RS15075	COG1953	Uracil, thiamine, allantoin
AOZ06_RS15095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOZ06_RS15105	COG0750	zinc metalloprotease
AOZ06_RS15115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOZ06_RS15130	COG0076	glutamate decarboxylase activity
AOZ06_RS15135	COG2850	peptidyl-arginine hydroxylation
AOZ06_RS15145	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS15155	COG1309	transcriptional regulator
AOZ06_RS15160	COG0539	negative regulation of cytoplasmic translation
AOZ06_RS15180	COG0183	Belongs to the thiolase family
AOZ06_RS15185	COG1024	Enoyl-CoA hydratase
AOZ06_RS15185	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ06_RS15220	COG2172	sigma factor antagonist activity
AOZ06_RS15235	COG1793	dna ligase
AOZ06_RS15235	COG3285	dna ligase
AOZ06_RS15265	COG1131	(ABC) transporter
AOZ06_RS15275	COG1476	TRANSCRIPTIONal
AOZ06_RS15285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOZ06_RS15290	COG0484	heat shock protein binding
AOZ06_RS15330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOZ06_RS15335	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOZ06_RS15340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOZ06_RS15345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOZ06_RS15350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOZ06_RS15360	COG0165	Argininosuccinate lyase
AOZ06_RS15370	COG2094	Belongs to the DNA glycosylase MPG family
AOZ06_RS15375	COG2124	cytochrome p450
AOZ06_RS15380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOZ06_RS15405	COG0647	UMP catabolic process
AOZ06_RS15420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOZ06_RS15440	COG0504	CTP synthase activity
AOZ06_RS15445	COG0494	nUDIX hydrolase
AOZ06_RS15465	COG1024	Enoyl-CoA hydratase
AOZ06_RS15490	COG0531	amino acid
AOZ06_RS15500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AOZ06_RS15505	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS15560	COG1733	regulation of RNA biosynthetic process
AOZ06_RS15565	COG2197	response regulator
AOZ06_RS15570	COG4585	Histidine kinase
AOZ06_RS15575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOZ06_RS15580	COG1760	l-serine dehydratase
AOZ06_RS15585	COG2186	Transcriptional regulator
AOZ06_RS15615	COG2205	protein histidine kinase activity
AOZ06_RS15620	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS15630	COG0129	dihydroxy-acid dehydratase activity
AOZ06_RS15675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOZ06_RS15680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOZ06_RS15690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOZ06_RS15710	COG3629	intracellular signal transduction
AOZ06_RS15710	COG3903	Transcriptional regulator
AOZ06_RS15715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOZ06_RS15735	COG1160	GTP binding
AOZ06_RS15760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOZ06_RS15775	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AOZ06_RS15800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOZ06_RS15865	COG2826	transposase and inactivated derivatives, IS30 family
AOZ06_RS15880	COG3903	Transcriptional regulator
AOZ06_RS15880	COG3629	intracellular signal transduction
AOZ06_RS15915	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS15915	COG2319	Wd-40 repeat
AOZ06_RS15955	COG0222	ribosome binding
AOZ06_RS16010	COG2801	Transposase and inactivated derivatives
AOZ06_RS16040	COG2205	protein histidine kinase activity
AOZ06_RS16055	COG1136	(ABC) transporter
AOZ06_RS16055	COG0577	efflux transmembrane transporter activity
AOZ06_RS16060	COG0577	efflux transmembrane transporter activity
AOZ06_RS16060	COG1136	(ABC) transporter
AOZ06_RS16120	COG1228	amidohydrolase
AOZ06_RS16200	COG0583	DNA-binding transcription factor activity
AOZ06_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS16240	COG2378	regulation of single-species biofilm formation
AOZ06_RS16255	COG0583	DNA-binding transcription factor activity
AOZ06_RS16305	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOZ06_RS16360	COG0596	Alpha beta hydrolase
AOZ06_RS16390	COG1132	(ABC) transporter
AOZ06_RS16400	COG0598	Magnesium transport protein CorA
AOZ06_RS16420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS16430	COG2226	methyltransferase
AOZ06_RS16505	COG3321	synthase
AOZ06_RS16505	COG0604	alcohol dehydrogenase
AOZ06_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS16510	COG3629	intracellular signal transduction
AOZ06_RS16510	COG3903	Transcriptional regulator
AOZ06_RS16575	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS16575	COG2319	Wd-40 repeat
AOZ06_RS16675	COG0596	Alpha beta hydrolase
AOZ06_RS16700	COG0154	amidase activity
AOZ06_RS16750	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS16750	COG2319	Wd-40 repeat
AOZ06_RS16800	COG1366	Belongs to the anti-sigma-factor antagonist family
AOZ06_RS16805	COG1366	Belongs to the anti-sigma-factor antagonist family
AOZ06_RS16810	COG2172	sigma factor antagonist activity
AOZ06_RS16835	COG2326	polyphosphate kinase activity
AOZ06_RS16840	COG3647	Membrane
AOZ06_RS16845	COG2197	response regulator
AOZ06_RS16850	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS16850	COG2319	Wd-40 repeat
AOZ06_RS16870	COG0495	leucyl-tRNA aminoacylation
AOZ06_RS16875	COG1131	(ABC) transporter
AOZ06_RS16885	COG2124	cytochrome p450
AOZ06_RS16960	COG0667	Aldo Keto reductase
AOZ06_RS16980	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS16985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOZ06_RS16985	COG2070	2-Nitropropane dioxygenase
AOZ06_RS16990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS16990	COG4221	oxidoreductase activity
AOZ06_RS16990	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS16990	COG3321	synthase
AOZ06_RS16995	COG1509	lysine 2,3-aminomutase activity
AOZ06_RS17030	COG0583	DNA-binding transcription factor activity
AOZ06_RS17130	COG1309	transcriptional regulator
AOZ06_RS17140	COG2226	methyltransferase
AOZ06_RS17165	COG0154	amidase activity
AOZ06_RS17170	COG1309	transcriptional regulator
AOZ06_RS17245	COG0477	Major facilitator Superfamily
AOZ06_RS17260	COG0596	Alpha beta hydrolase
AOZ06_RS17270	COG0604	alcohol dehydrogenase
AOZ06_RS17270	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS17270	COG3321	synthase
AOZ06_RS17300	COG1309	transcriptional regulator
AOZ06_RS17305	COG3629	intracellular signal transduction
AOZ06_RS17310	COG0443	Heat shock 70 kDa protein
AOZ06_RS17315	COG2197	response regulator
AOZ06_RS17320	COG1126	abc transporter atp-binding protein
AOZ06_RS17330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS17350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS17385	COG0667	Aldo Keto reductase
AOZ06_RS17410	COG0596	Alpha beta hydrolase
AOZ06_RS17445	COG2124	cytochrome p450
AOZ06_RS17450	COG1280	lysine exporter protein (LysE YggA)
AOZ06_RS17465	COG0583	DNA-binding transcription factor activity
AOZ06_RS17545	COG1136	(ABC) transporter
AOZ06_RS17550	COG0577	efflux transmembrane transporter activity
AOZ06_RS17570	COG0740	serine-type endopeptidase activity
AOZ06_RS17575	COG0740	serine-type endopeptidase activity
AOZ06_RS17580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS17590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOZ06_RS17605	COG1725	Transcriptional regulator
AOZ06_RS17610	COG0442	prolyl-tRNA aminoacylation
AOZ06_RS17675	COG0596	Alpha beta hydrolase
AOZ06_RS17700	COG2132	Multicopper oxidase
AOZ06_RS17740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS17750	COG1120	ATPase activity
AOZ06_RS17840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AOZ06_RS17850	COG2746	aminoglycoside 3-N-acetyltransferase activity
AOZ06_RS17855	COG3226	Transcriptional regulator
AOZ06_RS17875	COG0726	polysaccharide deacetylase
AOZ06_RS17915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS17920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS17945	COG0583	DNA-binding transcription factor activity
AOZ06_RS17950	COG1271	oxidase subunit
AOZ06_RS17960	COG4988	ABC transporter
AOZ06_RS17965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOZ06_RS17985	COG2814	Major facilitator Superfamily
AOZ06_RS18005	COG0590	tRNA wobble adenosine to inosine editing
AOZ06_RS18025	COG0477	Major facilitator Superfamily
AOZ06_RS18040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS18045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOZ06_RS18060	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS18065	COG1535	isochorismatase
AOZ06_RS18065	COG3433	isochorismatase activity
AOZ06_RS18075	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS18110	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS18110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOZ06_RS18125	COG2072	flavoprotein involved in K transport
AOZ06_RS18130	COG2264	protein methyltransferase activity
AOZ06_RS18135	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS18145	COG2409	Drug exporters of the RND superfamily
AOZ06_RS18150	COG2130	NADP-dependent
AOZ06_RS18195	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOZ06_RS18200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS18220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOZ06_RS18225	COG2375	cellular response to nickel ion
AOZ06_RS18230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS18235	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS18240	COG1120	ATPase activity
AOZ06_RS18255	COG1132	(ABC) transporter
AOZ06_RS18260	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS18265	COG1169	isochorismate synthase
AOZ06_RS18270	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOZ06_RS18275	COG3433	isochorismatase activity
AOZ06_RS18275	COG1535	isochorismatase
AOZ06_RS18280	COG1535	isochorismatase
AOZ06_RS18280	COG3433	isochorismatase activity
AOZ06_RS18285	COG0076	glutamate decarboxylase activity
AOZ06_RS18295	COG4977	sequence-specific DNA binding
AOZ06_RS18340	COG1140	nitrate reductase beta subunit
AOZ06_RS18355	COG2197	response regulator
AOZ06_RS18360	COG3851	Histidine kinase
AOZ06_RS18380	COG4977	sequence-specific DNA binding
AOZ06_RS18405	COG2267	carboxylic ester hydrolase activity
AOZ06_RS18425	COG1476	TRANSCRIPTIONal
AOZ06_RS18470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOZ06_RS18480	COG3511	phospholipase C
AOZ06_RS18485	COG1501	Belongs to the glycosyl hydrolase 31 family
AOZ06_RS18495	COG0737	Belongs to the 5'-nucleotidase family
AOZ06_RS18530	COG0596	Alpha beta hydrolase
AOZ06_RS18550	COG0277	FAD linked oxidase domain protein
AOZ06_RS18565	COG0367	asparagine synthase
AOZ06_RS18585	COG0587	DNA-directed DNA polymerase activity
AOZ06_RS18600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS18605	COG0515	serine threonine protein kinase
AOZ06_RS18690	COG0022	dehydrogenase e1 component
AOZ06_RS18695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOZ06_RS18700	COG4585	Histidine kinase
AOZ06_RS18705	COG2197	response regulator
AOZ06_RS18710	COG0825	malonyl-CoA metabolic process
AOZ06_RS18710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AOZ06_RS18715	COG0511	ligase activity, forming carbon-carbon bonds
AOZ06_RS18720	COG0439	Biotin carboxylase
AOZ06_RS18725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOZ06_RS18735	COG0662	Cupin 2, conserved barrel domain protein
AOZ06_RS18745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOZ06_RS18790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS18815	COG2084	Dehydrogenase
AOZ06_RS18835	COG2197	response regulator
AOZ06_RS18850	COG4585	Histidine kinase
AOZ06_RS18855	COG2197	response regulator
AOZ06_RS18870	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOZ06_RS18875	COG0512	Glutamine amidotransferase of anthranilate synthase
AOZ06_RS18875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOZ06_RS18880	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS18890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ06_RS18915	COG2318	DinB family
AOZ06_RS18920	COG2813	Specifically methylates the guanine in position
AOZ06_RS18935	COG2271	Major facilitator Superfamily
AOZ06_RS18970	COG4977	sequence-specific DNA binding
AOZ06_RS18980	COG0583	DNA-binding transcription factor activity
AOZ06_RS19000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOZ06_RS19060	COG2197	response regulator
AOZ06_RS19080	COG0586	Pfam SNARE associated Golgi protein
AOZ06_RS19110	COG0252	asparaginase activity
AOZ06_RS19130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOZ06_RS19145	COG3629	intracellular signal transduction
AOZ06_RS19145	COG3903	Transcriptional regulator
AOZ06_RS19175	COG0277	FAD linked oxidase domain protein
AOZ06_RS19175	COG0247	lactate metabolic process
AOZ06_RS19215	COG0435	Glutathione S-transferase
AOZ06_RS19270	COG0667	Aldo Keto reductase
AOZ06_RS19335	COG3033	Beta-eliminating lyase
AOZ06_RS19380	COG2755	lipolytic protein G-D-S-L family
AOZ06_RS19425	COG3629	intracellular signal transduction
AOZ06_RS19425	COG3903	Transcriptional regulator
AOZ06_RS19475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOZ06_RS19485	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS19490	COG1024	Enoyl-CoA hydratase
AOZ06_RS19495	COG1309	transcriptional regulator
AOZ06_RS19505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOZ06_RS19525	COG2197	response regulator
AOZ06_RS19545	COG2172	sigma factor antagonist activity
AOZ06_RS19560	COG0583	DNA-binding transcription factor activity
AOZ06_RS19575	COG0475	glutathione-regulated potassium exporter activity
AOZ06_RS19600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOZ06_RS19650	COG4585	Histidine kinase
AOZ06_RS19655	COG2197	response regulator
AOZ06_RS19680	COG0702	epimerase
AOZ06_RS19705	COG1011	Hydrolase
AOZ06_RS19740	COG1595	DNA-templated transcription, initiation
AOZ06_RS19775	COG4585	Histidine kinase
AOZ06_RS19815	COG1137	ATPase activity
AOZ06_RS19840	COG4266	Belongs to the allantoicase family
AOZ06_RS19850	COG2252	PERMEase
AOZ06_RS19855	COG0590	tRNA wobble adenosine to inosine editing
AOZ06_RS19860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOZ06_RS19880	COG2351	hydroxyisourate hydrolase activity
AOZ06_RS19890	COG3835	regulator
AOZ06_RS19900	COG1309	transcriptional regulator
AOZ06_RS19905	COG3903	Transcriptional regulator
AOZ06_RS19905	COG3629	intracellular signal transduction
AOZ06_RS19910	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS19925	COG1733	regulation of RNA biosynthetic process
AOZ06_RS19955	COG2197	response regulator
AOZ06_RS19965	COG2124	cytochrome p450
AOZ06_RS19975	COG1228	amidohydrolase
AOZ06_RS19995	COG3250	beta-galactosidase activity
AOZ06_RS20005	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS20020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOZ06_RS20030	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AOZ06_RS20045	COG1522	sequence-specific DNA binding
AOZ06_RS20055	COG1309	transcriptional regulator
AOZ06_RS20060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOZ06_RS20070	COG1309	transcriptional regulator
AOZ06_RS20080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOZ06_RS20090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS20105	COG3883	PFAM NLP P60 protein
AOZ06_RS20105	COG0791	NLP P60 protein
AOZ06_RS20110	COG2130	NADP-dependent
AOZ06_RS20115	COG0583	DNA-binding transcription factor activity
AOZ06_RS20140	COG0657	acetylesterase activity
AOZ06_RS20150	COG0714	Associated with various cellular activities
AOZ06_RS20180	COG2205	protein histidine kinase activity
AOZ06_RS20185	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS20190	COG0577	efflux transmembrane transporter activity
AOZ06_RS20200	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOZ06_RS20210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOZ06_RS20230	COG1175	transmembrane transport
AOZ06_RS20235	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS20240	COG1486	melibiose metabolic process
AOZ06_RS20265	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AOZ06_RS20280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS20295	COG2936	dipeptidyl-peptidase activity
AOZ06_RS20300	COG4221	oxidoreductase activity
AOZ06_RS20310	COG0215	cysteine-tRNA ligase activity
AOZ06_RS20325	COG0140	phosphoribosyl-ATP diphosphatase activity
AOZ06_RS20330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOZ06_RS20345	COG0517	IMP dehydrogenase activity
AOZ06_RS20345	COG1994	Peptidase M50
AOZ06_RS20380	COG1222	aaa ATPase
AOZ06_RS20415	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOZ06_RS20420	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOZ06_RS20425	COG1674	ftsk spoiiie
AOZ06_RS20430	COG1597	lipid kinase activity
AOZ06_RS20435	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOZ06_RS20445	COG2378	regulation of single-species biofilm formation
AOZ06_RS20480	COG4552	Acetyltransferase involved in intracellular survival and related
AOZ06_RS20525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOZ06_RS20550	COG2233	PERMEase
AOZ06_RS20610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOZ06_RS20615	COG3706	GGDEF domain
AOZ06_RS20635	COG2186	Transcriptional regulator
AOZ06_RS20655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOZ06_RS20660	COG4585	Histidine kinase
AOZ06_RS20665	COG2197	response regulator
AOZ06_RS20670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS20685	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOZ06_RS20705	COG0488	(ABC) transporter
AOZ06_RS20720	COG1132	(ABC) transporter
AOZ06_RS20725	COG4821	SIS domain
AOZ06_RS20730	COG0596	Alpha beta hydrolase
AOZ06_RS20740	COG1316	TRANSCRIPTIONal
AOZ06_RS20760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOZ06_RS20770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOZ06_RS20775	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AOZ06_RS20780	COG0693	protein deglycase activity
AOZ06_RS20795	COG1366	Belongs to the anti-sigma-factor antagonist family
AOZ06_RS20815	COG1733	regulation of RNA biosynthetic process
AOZ06_RS20870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOZ06_RS20880	COG1070	Carbohydrate kinase
AOZ06_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS20885	COG3347	Dehydrogenase
AOZ06_RS20890	COG4952	isomerase
AOZ06_RS20895	COG1609	Transcriptional regulator
AOZ06_RS20915	COG4585	Histidine kinase
AOZ06_RS20920	COG2197	response regulator
AOZ06_RS20945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ06_RS20960	COG3321	synthase
AOZ06_RS20960	COG0604	alcohol dehydrogenase
AOZ06_RS20960	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS20965	COG3321	synthase
AOZ06_RS20965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS21005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ06_RS21010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS21025	COG2018	Roadblock/LC7 domain
AOZ06_RS21045	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS21060	COG2188	Transcriptional regulator
AOZ06_RS21130	COG0300	oxidoreductase activity
AOZ06_RS21170	COG1940	carbohydrate kinase activity
AOZ06_RS21175	COG2115	Belongs to the xylose isomerase family
AOZ06_RS21185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOZ06_RS21195	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AOZ06_RS21195	COG0493	'glutamate synthase
AOZ06_RS21200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOZ06_RS21230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOZ06_RS21240	COG2217	Heavy metal translocating P-type atpase
AOZ06_RS21245	COG1309	transcriptional regulator
AOZ06_RS21260	COG3104	oligopeptide transport
AOZ06_RS21265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOZ06_RS21270	COG1278	Cold shock
AOZ06_RS21285	COG3759	membrane
AOZ06_RS21300	COG3959	Transketolase, thiamine diphosphate binding domain
AOZ06_RS21305	COG3958	Transketolase
AOZ06_RS21345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AOZ06_RS21350	COG2207	Transcriptional regulator
AOZ06_RS21365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS21370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS21375	COG2226	methyltransferase
AOZ06_RS21385	COG0242	peptide deformylase activity
AOZ06_RS21395	COG3845	ABC transporter
AOZ06_RS21430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AOZ06_RS21440	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS21445	COG1024	Enoyl-CoA hydratase
AOZ06_RS21460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOZ06_RS21470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOZ06_RS21480	COG0525	valine-tRNA ligase activity
AOZ06_RS21495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOZ06_RS21500	COG0704	Plays a role in the regulation of phosphate uptake
AOZ06_RS21515	COG2080	2 iron, 2 sulfur cluster binding
AOZ06_RS21520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AOZ06_RS21525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOZ06_RS21530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOZ06_RS21530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOZ06_RS21550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOZ06_RS21560	COG1942	4-Oxalocrotonate Tautomerase
AOZ06_RS21565	COG1595	DNA-templated transcription, initiation
AOZ06_RS21585	COG0596	Alpha beta hydrolase
AOZ06_RS21600	COG2226	methyltransferase
AOZ06_RS21635	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOZ06_RS21645	COG2814	Major facilitator Superfamily
AOZ06_RS21660	COG0656	L-ascorbic acid biosynthetic process
AOZ06_RS21665	COG0435	Glutathione S-transferase
AOZ06_RS21675	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOZ06_RS21680	COG0159	tryptophan synthase activity
AOZ06_RS21685	COG0133	tryptophan synthase activity
AOZ06_RS21690	COG0134	indole-3-glycerol-phosphate synthase activity
AOZ06_RS21695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOZ06_RS21700	COG0512	Glutamine amidotransferase of anthranilate synthase
AOZ06_RS21700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOZ06_RS21705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOZ06_RS21710	COG2124	cytochrome p450
AOZ06_RS21725	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS21730	COG0662	Cupin 2, conserved barrel domain protein
AOZ06_RS21745	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AOZ06_RS21770	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AOZ06_RS21785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOZ06_RS21810	COG0492	ferredoxin-NADP+ reductase activity
AOZ06_RS21820	COG0028	Belongs to the TPP enzyme family
AOZ06_RS21840	COG2770	Histidine kinase
AOZ06_RS21840	COG2208	phosphoserine phosphatase activity
AOZ06_RS21870	COG2205	protein histidine kinase activity
AOZ06_RS21875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOZ06_RS21890	COG1573	uracil-dna glycosylase
AOZ06_RS21915	COG0477	Major facilitator Superfamily
AOZ06_RS21920	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS21920	COG2319	Wd-40 repeat
AOZ06_RS21930	COG2367	Beta-lactamase
AOZ06_RS21950	COG3971	2-oxopent-4-enoate hydratase activity
AOZ06_RS21965	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOZ06_RS22000	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS22030	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOZ06_RS22045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS22080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AOZ06_RS22085	COG0134	indole-3-glycerol-phosphate synthase activity
AOZ06_RS22090	COG0135	phosphoribosylanthranilate isomerase activity
AOZ06_RS22095	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AOZ06_RS22105	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS22110	COG0662	Cupin 2, conserved barrel domain protein
AOZ06_RS22115	COG0159	tryptophan synthase activity
AOZ06_RS22140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS22150	COG2234	aminopeptidase activity
AOZ06_RS22155	COG2234	aminopeptidase activity
AOZ06_RS22160	COG2234	aminopeptidase activity
AOZ06_RS22245	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS22250	COG1175	transmembrane transport
AOZ06_RS22315	COG0477	Major facilitator Superfamily
AOZ06_RS22325	COG1169	isochorismate synthase
AOZ06_RS22330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOZ06_RS22390	COG3835	regulator
AOZ06_RS22465	COG4585	Histidine kinase
AOZ06_RS22470	COG2197	response regulator
AOZ06_RS22475	COG3629	intracellular signal transduction
AOZ06_RS22505	COG2130	NADP-dependent
AOZ06_RS22510	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS22530	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS22570	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AOZ06_RS22595	COG0477	Major facilitator Superfamily
AOZ06_RS22615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOZ06_RS22620	COG0142	geranyltranstransferase activity
AOZ06_RS22625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOZ06_RS22630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOZ06_RS22650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AOZ06_RS22655	COG2197	response regulator
AOZ06_RS22665	COG4585	Histidine kinase
AOZ06_RS22675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOZ06_RS22700	COG1132	(ABC) transporter
AOZ06_RS22735	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS22745	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AOZ06_RS22750	COG0531	amino acid
AOZ06_RS22765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOZ06_RS22790	COG0372	Belongs to the citrate synthase family
AOZ06_RS22800	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS22805	COG2814	Major facilitator Superfamily
AOZ06_RS22830	COG0657	acetylesterase activity
AOZ06_RS22835	COG2375	cellular response to nickel ion
AOZ06_RS22835	COG1132	(ABC) transporter
AOZ06_RS22840	COG1132	(ABC) transporter
AOZ06_RS22850	COG1104	cysteine desulfurase activity
AOZ06_RS22870	COG1404	Belongs to the peptidase S8 family
AOZ06_RS22880	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS22880	COG2319	Wd-40 repeat
AOZ06_RS22895	COG1309	transcriptional regulator
AOZ06_RS22905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOZ06_RS22910	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AOZ06_RS22915	COG2080	2 iron, 2 sulfur cluster binding
AOZ06_RS22930	COG1573	uracil-dna glycosylase
AOZ06_RS22980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS22985	COG1024	Enoyl-CoA hydratase
AOZ06_RS23000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOZ06_RS23030	COG2124	cytochrome p450
AOZ06_RS23050	COG0628	permease
AOZ06_RS23070	COG0531	amino acid
AOZ06_RS23085	COG3387	PFAM Glycoside hydrolase 15-related
AOZ06_RS23095	COG1121	(ABC) transporter
AOZ06_RS23100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOZ06_RS23105	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS23110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ06_RS23205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOZ06_RS23225	COG2226	methyltransferase
AOZ06_RS23230	COG2205	protein histidine kinase activity
AOZ06_RS23235	COG2828	Protein conserved in bacteria
AOZ06_RS23300	COG1819	glycosyl
AOZ06_RS23330	COG0667	Aldo Keto reductase
AOZ06_RS23405	COG1228	amidohydrolase
AOZ06_RS23445	COG3976	FMN-binding domain protein
AOZ06_RS23445	COG1053	succinate dehydrogenase
AOZ06_RS23445	COG0431	NADPH-dependent FMN reductase
AOZ06_RS23470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOZ06_RS23500	COG2319	Wd-40 repeat
AOZ06_RS23500	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS23505	COG2814	Major facilitator Superfamily
AOZ06_RS23560	COG2208	phosphoserine phosphatase activity
AOZ06_RS23565	COG0248	Ppx GppA phosphatase
AOZ06_RS23580	COG2319	Wd-40 repeat
AOZ06_RS23580	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS23590	COG0387	Pfam Sodium calcium exchanger
AOZ06_RS23600	COG3540	Alkaline phosphatase
AOZ06_RS23610	COG3903	Transcriptional regulator
AOZ06_RS23610	COG3629	intracellular signal transduction
AOZ06_RS23690	COG4106	trans-aconitate 2-methyltransferase activity
AOZ06_RS23715	COG1309	transcriptional regulator
AOZ06_RS23745	COG2124	cytochrome p450
AOZ06_RS23800	COG4585	Histidine kinase
AOZ06_RS23805	COG2197	response regulator
AOZ06_RS23815	COG2226	methyltransferase
AOZ06_RS23820	COG1309	transcriptional regulator
AOZ06_RS23830	COG0531	amino acid
AOZ06_RS23845	COG2201	protein-glutamate methylesterase activity
AOZ06_RS23870	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS23945	COG1309	transcriptional regulator
AOZ06_RS23985	COG1113	amino acid transport
AOZ06_RS23995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOZ06_RS24050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOZ06_RS24080	COG1295	ribonuclease BN
AOZ06_RS24120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS24140	COG2197	response regulator
AOZ06_RS24145	COG4585	Histidine kinase
AOZ06_RS24175	COG2201	protein-glutamate methylesterase activity
AOZ06_RS24210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS24215	COG0583	DNA-binding transcription factor activity
AOZ06_RS24240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOZ06_RS24245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOZ06_RS24325	COG0596	Alpha beta hydrolase
AOZ06_RS24330	COG0583	DNA-binding transcription factor activity
AOZ06_RS24355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ06_RS24395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOZ06_RS24400	COG2261	transglycosylase associated protein
AOZ06_RS24410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS24425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOZ06_RS24485	COG0673	inositol 2-dehydrogenase activity
AOZ06_RS24500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOZ06_RS24520	COG1609	Transcriptional regulator
AOZ06_RS24525	COG1879	ABC-type sugar transport system periplasmic component
AOZ06_RS24530	COG1129	ABC transporter
AOZ06_RS24535	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS24540	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS24585	COG2130	NADP-dependent
AOZ06_RS24600	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOZ06_RS24600	COG1902	pentaerythritol trinitrate reductase activity
AOZ06_RS24615	COG2197	response regulator
AOZ06_RS24620	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOZ06_RS24630	COG1045	serine acetyltransferase
AOZ06_RS24635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ06_RS24640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOZ06_RS24640	COG0515	serine threonine protein kinase
AOZ06_RS24650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOZ06_RS24695	COG3118	belongs to the thioredoxin family
AOZ06_RS24705	COG0583	DNA-binding transcription factor activity
AOZ06_RS24730	COG2072	flavoprotein involved in K transport
AOZ06_RS24850	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS24850	COG1672	PFAM Archaeal ATPase
AOZ06_RS24855	COG0028	Belongs to the TPP enzyme family
AOZ06_RS24860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS24865	COG1231	oxidoreductase activity
AOZ06_RS24870	COG0667	Aldo Keto reductase
AOZ06_RS24890	COG1063	alcohol dehydrogenase
AOZ06_RS24900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOZ06_RS24905	COG1228	amidohydrolase
AOZ06_RS24920	COG0443	Heat shock 70 kDa protein
AOZ06_RS24930	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOZ06_RS24950	COG0702	epimerase
AOZ06_RS24960	COG0492	ferredoxin-NADP+ reductase activity
AOZ06_RS24980	COG2326	polyphosphate kinase activity
AOZ06_RS25040	COG1309	transcriptional regulator
AOZ06_RS25060	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS25080	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS25095	COG0604	alcohol dehydrogenase
AOZ06_RS25120	COG1733	regulation of RNA biosynthetic process
AOZ06_RS25135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOZ06_RS25155	COG3629	intracellular signal transduction
AOZ06_RS25155	COG3903	Transcriptional regulator
AOZ06_RS25160	COG3903	Transcriptional regulator
AOZ06_RS25160	COG3629	intracellular signal transduction
AOZ06_RS25190	COG0456	acetyltransferase
AOZ06_RS25220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS25225	COG0583	DNA-binding transcription factor activity
AOZ06_RS25260	COG1309	transcriptional regulator
AOZ06_RS25330	COG1672	PFAM Archaeal ATPase
AOZ06_RS25330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS25340	COG0653	protein targeting
AOZ06_RS25345	COG2814	Major facilitator Superfamily
AOZ06_RS25365	COG1063	alcohol dehydrogenase
AOZ06_RS25370	COG1228	amidohydrolase
AOZ06_RS25375	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS25395	COG0601	transmembrane transport
AOZ06_RS25400	COG0444	Belongs to the ABC transporter superfamily
AOZ06_RS25405	COG4172	Belongs to the ABC transporter superfamily
AOZ06_RS25420	COG2197	response regulator
AOZ06_RS25425	COG4585	Histidine kinase
AOZ06_RS25450	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS25460	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AOZ06_RS25470	COG2814	Major facilitator Superfamily
AOZ06_RS25480	COG0477	Major facilitator Superfamily
AOZ06_RS25485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS25525	COG2197	response regulator
AOZ06_RS25530	COG4585	Histidine kinase
AOZ06_RS25570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS25580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AOZ06_RS25595	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS25605	COG2271	Major facilitator Superfamily
AOZ06_RS25635	COG0444	Belongs to the ABC transporter superfamily
AOZ06_RS25640	COG4608	Belongs to the ABC transporter superfamily
AOZ06_RS25670	COG5006	permease, DMT superfamily
AOZ06_RS25675	COG0583	DNA-binding transcription factor activity
AOZ06_RS25705	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ06_RS25725	COG0477	Major facilitator Superfamily
AOZ06_RS25745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOZ06_RS25750	COG0436	Aminotransferase
AOZ06_RS25775	COG0300	oxidoreductase activity
AOZ06_RS25810	COG0640	Transcriptional regulator
AOZ06_RS25820	COG2226	methyltransferase
AOZ06_RS25825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS25835	COG0583	DNA-binding transcription factor activity
AOZ06_RS25855	COG1834	amidinotransferase
AOZ06_RS25890	COG2814	Major facilitator Superfamily
AOZ06_RS25915	COG0477	Major facilitator Superfamily
AOZ06_RS25975	COG1733	regulation of RNA biosynthetic process
AOZ06_RS25985	COG0714	Associated with various cellular activities
AOZ06_RS26000	COG3321	synthase
AOZ06_RS26000	COG0604	alcohol dehydrogenase
AOZ06_RS26005	COG3321	synthase
AOZ06_RS26005	COG0604	alcohol dehydrogenase
AOZ06_RS26005	COG3321	synthase
AOZ06_RS26005	COG0604	alcohol dehydrogenase
AOZ06_RS26030	COG0148	phosphopyruvate hydratase activity
AOZ06_RS26035	COG0302	gtp cyclohydrolase
AOZ06_RS26040	COG0602	queuosine metabolic process
AOZ06_RS26075	COG3424	synthase
AOZ06_RS26080	COG2124	cytochrome p450
AOZ06_RS26100	COG2124	cytochrome p450
AOZ06_RS26110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS26120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS26125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS26130	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOZ06_RS26155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS26170	COG0444	Belongs to the ABC transporter superfamily
AOZ06_RS26175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS26185	COG0747	negative chemotaxis
AOZ06_RS26200	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS26260	COG1755	Isoprenylcysteine carboxyl methyltransferase
AOZ06_RS26295	COG3546	catalase activity
AOZ06_RS26300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOZ06_RS26340	COG1595	DNA-templated transcription, initiation
AOZ06_RS26365	COG1302	Protein conserved in bacteria
AOZ06_RS26385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS26400	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS26425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOZ06_RS26445	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS26465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOZ06_RS26470	COG0646	methionine synthase
AOZ06_RS26470	COG1410	methionine synthase
AOZ06_RS26475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS26480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOZ06_RS26490	COG1595	DNA-templated transcription, initiation
AOZ06_RS26500	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS26520	COG5297	Belongs to the glycosyl hydrolase family 6
AOZ06_RS26545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ06_RS26560	COG0367	asparagine synthase
AOZ06_RS26580	COG0454	-acetyltransferase
AOZ06_RS26585	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS26585	COG3848	Pyruvate phosphate dikinase
AOZ06_RS26620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS26625	COG0596	Alpha beta hydrolase
AOZ06_RS26650	COG0527	aspartate kinase activity
AOZ06_RS26660	COG3119	arylsulfatase activity
AOZ06_RS26670	COG0789	Transcriptional regulator
AOZ06_RS26675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOZ06_RS26690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS26695	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS26695	COG3321	synthase
AOZ06_RS26695	COG0604	alcohol dehydrogenase
AOZ06_RS26705	COG2172	sigma factor antagonist activity
AOZ06_RS26710	COG3707	response regulator
AOZ06_RS26725	COG3293	Transposase
AOZ06_RS26730	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS26745	COG1404	Belongs to the peptidase S8 family
AOZ06_RS26750	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS26750	COG1672	PFAM Archaeal ATPase
AOZ06_RS26755	COG0604	alcohol dehydrogenase
AOZ06_RS26760	COG1476	TRANSCRIPTIONal
AOZ06_RS26770	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOZ06_RS26825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOZ06_RS26825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOZ06_RS26840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOZ06_RS26865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS26875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS26885	COG0515	serine threonine protein kinase
AOZ06_RS26915	COG3903	Transcriptional regulator
AOZ06_RS26915	COG3629	intracellular signal transduction
AOZ06_RS26925	COG1309	transcriptional regulator
AOZ06_RS26950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOZ06_RS26970	COG0667	Aldo Keto reductase
AOZ06_RS26975	COG1968	undecaprenyl-diphosphatase activity
AOZ06_RS27010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS27025	COG1309	transcriptional regulator
AOZ06_RS27030	COG2264	protein methyltransferase activity
AOZ06_RS27035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOZ06_RS27045	COG5504	Zn-dependent protease
AOZ06_RS27050	COG0300	oxidoreductase activity
AOZ06_RS27100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOZ06_RS27165	COG0583	DNA-binding transcription factor activity
AOZ06_RS27180	COG0596	Alpha beta hydrolase
AOZ06_RS27215	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS27230	COG1357	PFAM Pentapeptide repeats (8 copies)
AOZ06_RS27250	COG3620	sequence-specific DNA binding
AOZ06_RS27275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOZ06_RS27310	COG0667	Aldo Keto reductase
AOZ06_RS27345	COG1522	sequence-specific DNA binding
AOZ06_RS27365	COG0596	Alpha beta hydrolase
AOZ06_RS27395	COG0789	Transcriptional regulator
AOZ06_RS27400	COG3321	synthase
AOZ06_RS27400	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS27400	COG0604	alcohol dehydrogenase
AOZ06_RS27425	COG2205	protein histidine kinase activity
AOZ06_RS27465	COG0583	DNA-binding transcription factor activity
AOZ06_RS27475	COG1819	glycosyl
AOZ06_RS27485	COG0346	lactoylglutathione lyase activity
AOZ06_RS27495	COG0596	Alpha beta hydrolase
AOZ06_RS27505	COG1522	sequence-specific DNA binding
AOZ06_RS27535	COG1595	DNA-templated transcription, initiation
AOZ06_RS27550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOZ06_RS27570	COG1073	alpha beta
AOZ06_RS27575	COG1349	DNA-binding transcription factor activity
AOZ06_RS27580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOZ06_RS27590	COG1105	Belongs to the carbohydrate kinase PfkB family
AOZ06_RS27600	COG2409	Drug exporters of the RND superfamily
AOZ06_RS27615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AOZ06_RS27630	COG0596	Alpha beta hydrolase
AOZ06_RS27665	COG1366	Belongs to the anti-sigma-factor antagonist family
AOZ06_RS27675	COG2816	NAD+ diphosphatase activity
AOZ06_RS27715	COG0494	nUDIX hydrolase
AOZ06_RS27725	COG0406	alpha-ribazole phosphatase activity
AOZ06_RS27760	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOZ06_RS27785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS27795	COG4166	transmembrane transport
AOZ06_RS27805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ06_RS27820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS27840	COG3842	ATPase activity
AOZ06_RS27845	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS27850	COG3833	ABC-type maltose transport systems, permease component
AOZ06_RS27900	COG0584	glycerophosphoryl diester phosphodiesterase
AOZ06_RS27920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ06_RS27925	COG0463	Glycosyl transferase, family 2
AOZ06_RS27980	COG1607	acyl-coa hydrolase
AOZ06_RS27985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOZ06_RS27990	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOZ06_RS27995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOZ06_RS28000	COG0604	alcohol dehydrogenase
AOZ06_RS28030	COG0702	epimerase
AOZ06_RS28035	COG1733	regulation of RNA biosynthetic process
AOZ06_RS28040	COG0789	Transcriptional regulator
AOZ06_RS28050	COG1668	transmembrane transport
AOZ06_RS28055	COG4152	abc transporter atp-binding protein
AOZ06_RS28060	COG2197	response regulator
AOZ06_RS28065	COG4585	Histidine kinase
AOZ06_RS28070	COG2855	membrane
AOZ06_RS28085	COG3903	Transcriptional regulator
AOZ06_RS28085	COG3629	intracellular signal transduction
AOZ06_RS28105	COG1131	(ABC) transporter
AOZ06_RS28110	COG1725	Transcriptional regulator
AOZ06_RS28125	COG0477	Major facilitator Superfamily
AOZ06_RS28140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS28145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS28195	COG0471	metal ion transport
AOZ06_RS28225	COG1404	Belongs to the peptidase S8 family
AOZ06_RS28250	COG0640	Transcriptional regulator
AOZ06_RS28275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS28295	COG0477	Major facilitator Superfamily
AOZ06_RS28305	COG2197	response regulator
AOZ06_RS28325	COG0443	Heat shock 70 kDa protein
AOZ06_RS28360	COG0583	DNA-binding transcription factor activity
AOZ06_RS28365	COG1505	serine-type exopeptidase activity
AOZ06_RS28370	COG1309	transcriptional regulator
AOZ06_RS28390	COG0702	epimerase
AOZ06_RS28405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOZ06_RS28415	COG0667	Aldo Keto reductase
AOZ06_RS28440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOZ06_RS28445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOZ06_RS28455	COG1414	Transcriptional regulator
AOZ06_RS28460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOZ06_RS28475	COG0583	DNA-binding transcription factor activity
AOZ06_RS28485	COG1024	Enoyl-CoA hydratase
AOZ06_RS28495	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ06_RS28500	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS28515	COG2207	Transcriptional regulator
AOZ06_RS28520	COG0667	Aldo Keto reductase
AOZ06_RS28525	COG0477	Major facilitator Superfamily
AOZ06_RS28530	COG1802	Transcriptional regulator
AOZ06_RS28535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ06_RS28550	COG1674	ftsk spoiiie
AOZ06_RS28650	COG2301	Belongs to the HpcH HpaI aldolase family
AOZ06_RS28665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS28690	COG2197	response regulator
AOZ06_RS28725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS28740	COG0683	leucine binding
AOZ06_RS28760	COG0484	heat shock protein binding
AOZ06_RS28805	COG3266	domain, Protein
AOZ06_RS28815	COG1674	ftsk spoiiie
AOZ06_RS28820	COG1404	Belongs to the peptidase S8 family
AOZ06_RS28830	COG0464	growth
AOZ06_RS28865	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOZ06_RS28870	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AOZ06_RS28905	COG0596	Alpha beta hydrolase
AOZ06_RS28935	COG3631	Ketosteroid isomerase-related protein
AOZ06_RS28940	COG0702	epimerase
AOZ06_RS28995	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOZ06_RS29015	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS29025	COG0667	Aldo Keto reductase
AOZ06_RS29030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOZ06_RS29085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOZ06_RS29115	COG0583	DNA-binding transcription factor activity
AOZ06_RS29120	COG1228	amidohydrolase
AOZ06_RS29130	COG0277	FAD linked oxidase domain protein
AOZ06_RS29150	COG2814	Major facilitator Superfamily
AOZ06_RS29160	COG0789	Transcriptional regulator
AOZ06_RS29190	COG0583	DNA-binding transcription factor activity
AOZ06_RS29215	COG1846	Transcriptional regulator
AOZ06_RS29220	COG2226	methyltransferase
AOZ06_RS29250	COG0736	holo-[acyl-carrier-protein] synthase activity
AOZ06_RS29285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ06_RS29300	COG1672	PFAM Archaeal ATPase
AOZ06_RS29300	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS29315	COG0515	serine threonine protein kinase
AOZ06_RS29320	COG1942	4-Oxalocrotonate Tautomerase
AOZ06_RS29365	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS29370	COG1175	transmembrane transport
AOZ06_RS29380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS29400	COG2226	methyltransferase
AOZ06_RS29405	COG0640	Transcriptional regulator
AOZ06_RS29410	COG0798	PFAM Bile acid sodium symporter
AOZ06_RS29415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOZ06_RS29445	COG4585	Histidine kinase
AOZ06_RS29450	COG2197	response regulator
AOZ06_RS29515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ06_RS29585	COG1914	H( )-stimulated, divalent metal cation uptake system
AOZ06_RS29590	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AOZ06_RS29590	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AOZ06_RS29595	COG0300	oxidoreductase activity
AOZ06_RS29600	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AOZ06_RS29600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AOZ06_RS29605	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AOZ06_RS29610	COG0297	glycogen (starch) synthase activity
AOZ06_RS29620	COG0859	PFAM glycosyl transferase family 9
AOZ06_RS29630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOZ06_RS29645	COG2192	nodulation
AOZ06_RS29715	COG2197	response regulator
AOZ06_RS29725	COG2197	response regulator
AOZ06_RS29765	COG3903	Transcriptional regulator
AOZ06_RS29765	COG3629	intracellular signal transduction
AOZ06_RS29790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AOZ06_RS29795	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS29810	COG0019	diaminopimelate decarboxylase activity
AOZ06_RS29815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ06_RS29865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS29880	COG0006	proline dipeptidase activity
AOZ06_RS29885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOZ06_RS29940	COG2197	response regulator
AOZ06_RS29950	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS29955	COG0477	Major facilitator Superfamily
AOZ06_RS29985	COG2208	phosphoserine phosphatase activity
AOZ06_RS29995	COG0500	methyltransferase
AOZ06_RS30000	COG1131	(ABC) transporter
AOZ06_RS30005	COG2197	response regulator
AOZ06_RS30015	COG1733	regulation of RNA biosynthetic process
AOZ06_RS30040	COG2124	cytochrome p450
AOZ06_RS30045	COG2124	cytochrome p450
AOZ06_RS30050	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS30050	COG2319	Wd-40 repeat
AOZ06_RS30070	COG2319	Wd-40 repeat
AOZ06_RS30070	COG4249	Peptidase C14 caspase catalytic subunit p20
AOZ06_RS30095	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOZ06_RS30110	COG1733	regulation of RNA biosynthetic process
AOZ06_RS30115	COG2197	response regulator
AOZ06_RS30140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOZ06_RS30170	COG3291	Pkd domain containing protein
AOZ06_RS30190	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS30195	COG2205	protein histidine kinase activity
AOZ06_RS30220	COG0583	DNA-binding transcription factor activity
AOZ06_RS30230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOZ06_RS30250	COG3842	ATPase activity
AOZ06_RS30255	COG1177	transmembrane transport
AOZ06_RS30260	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOZ06_RS30270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ06_RS30275	COG0596	Alpha beta hydrolase
AOZ06_RS30280	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS30290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ06_RS30310	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS30320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOZ06_RS30325	COG1335	isochorismatase
AOZ06_RS30350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOZ06_RS30390	COG0747	negative chemotaxis
AOZ06_RS30420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOZ06_RS30430	COG2226	methyltransferase
AOZ06_RS30435	COG0477	Major facilitator Superfamily
AOZ06_RS30445	COG0604	alcohol dehydrogenase
AOZ06_RS30455	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS30460	COG1175	transmembrane transport
AOZ06_RS30475	COG1595	DNA-templated transcription, initiation
AOZ06_RS30485	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AOZ06_RS30485	COG3291	Pkd domain containing protein
AOZ06_RS30495	COG2124	cytochrome p450
AOZ06_RS30540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS30545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS30580	COG2814	Major facilitator Superfamily
AOZ06_RS30585	COG1609	Transcriptional regulator
AOZ06_RS30595	COG0709	Synthesizes selenophosphate from selenide and ATP
AOZ06_RS30605	COG1921	L-seryl-tRNASec selenium transferase activity
AOZ06_RS30635	COG2226	methyltransferase
AOZ06_RS30645	COG1063	alcohol dehydrogenase
AOZ06_RS30650	COG1414	Transcriptional regulator
AOZ06_RS30655	COG1486	melibiose metabolic process
AOZ06_RS30730	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS30740	COG0477	Major facilitator Superfamily
AOZ06_RS30745	COG2409	Drug exporters of the RND superfamily
AOZ06_RS30775	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ06_RS30795	COG3386	PFAM SMP-30 Gluconolaconase
AOZ06_RS30800	COG1522	sequence-specific DNA binding
AOZ06_RS30810	COG2175	clavaminate synthase activity
AOZ06_RS30815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AOZ06_RS30820	COG4521	taurine ABC transporter
AOZ06_RS30830	COG1794	racemase activity, acting on amino acids and derivatives
AOZ06_RS30855	COG2197	response regulator
AOZ06_RS30860	COG4585	Histidine kinase
AOZ06_RS30895	COG3540	Alkaline phosphatase
AOZ06_RS30910	COG0405	Gamma-glutamyltransferase
AOZ06_RS30925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS30945	COG0135	phosphoribosylanthranilate isomerase activity
AOZ06_RS30970	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS30995	COG2132	Multicopper oxidase
AOZ06_RS31000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOZ06_RS31025	COG2124	cytochrome p450
AOZ06_RS31050	COG0604	alcohol dehydrogenase
AOZ06_RS31050	COG3321	synthase
AOZ06_RS31070	COG0477	Major facilitator Superfamily
AOZ06_RS31095	COG0596	Alpha beta hydrolase
AOZ06_RS31100	COG0477	Major facilitator Superfamily
AOZ06_RS31110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ06_RS31130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOZ06_RS31170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS31200	COG4977	sequence-specific DNA binding
AOZ06_RS31200	COG1917	Cupin 2, conserved barrel domain protein
AOZ06_RS31260	COG1024	Enoyl-CoA hydratase
AOZ06_RS31260	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ06_RS31265	COG0488	(ABC) transporter
AOZ06_RS31290	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AOZ06_RS31300	COG0183	Belongs to the thiolase family
AOZ06_RS31310	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS31320	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS31330	COG1129	ABC transporter
AOZ06_RS31340	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS31395	COG0154	amidase activity
AOZ06_RS31425	COG0531	amino acid
AOZ06_RS31440	COG2207	Transcriptional regulator
AOZ06_RS31445	COG2223	nitrite transmembrane transporter activity
AOZ06_RS31485	COG0346	lactoylglutathione lyase activity
AOZ06_RS31490	COG0400	carboxylic ester hydrolase activity
AOZ06_RS31505	COG1136	(ABC) transporter
AOZ06_RS31505	COG0577	efflux transmembrane transporter activity
AOZ06_RS31510	COG0577	efflux transmembrane transporter activity
AOZ06_RS31510	COG1136	(ABC) transporter
AOZ06_RS31515	COG4585	Histidine kinase
AOZ06_RS31520	COG2197	response regulator
AOZ06_RS31535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS31540	COG2364	Membrane
AOZ06_RS31560	COG0277	FAD linked oxidase domain protein
AOZ06_RS31595	COG1653	transport
AOZ06_RS31630	COG3012	SEC-C Motif Domain Protein
AOZ06_RS31660	COG2755	lipolytic protein G-D-S-L family
AOZ06_RS31660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOZ06_RS31685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ06_RS31690	COG1215	transferase activity, transferring glycosyl groups
AOZ06_RS31695	COG2124	cytochrome p450
AOZ06_RS31700	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS31705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOZ06_RS31755	COG2205	protein histidine kinase activity
AOZ06_RS31755	COG0784	Response regulator, receiver
AOZ06_RS31755	COG5002	protein histidine kinase activity
AOZ06_RS31775	COG0259	pyridoxamine-phosphate oxidase activity
AOZ06_RS31785	COG2207	Transcriptional regulator
AOZ06_RS31810	COG4977	sequence-specific DNA binding
AOZ06_RS31825	COG1937	Protein conserved in bacteria
AOZ06_RS31840	COG0588	phosphoglycerate mutase activity
AOZ06_RS31850	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS31855	COG3795	YCII-related domain
AOZ06_RS31870	COG2124	cytochrome p450
AOZ06_RS31875	COG1132	(ABC) transporter
AOZ06_RS31885	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS31895	COG2197	response regulator
AOZ06_RS31900	COG4585	Histidine kinase
AOZ06_RS31940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOZ06_RS31950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOZ06_RS31975	COG1253	flavin adenine dinucleotide binding
AOZ06_RS31980	COG0596	Alpha beta hydrolase
AOZ06_RS31985	COG1388	LysM domain
AOZ06_RS31985	COG3942	CHAP domain
AOZ06_RS31990	COG2132	Multicopper oxidase
AOZ06_RS32000	COG2409	Drug exporters of the RND superfamily
AOZ06_RS32005	COG3629	intracellular signal transduction
AOZ06_RS32010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOZ06_RS32015	COG1846	Transcriptional regulator
AOZ06_RS32020	COG2345	Transcriptional regulator
AOZ06_RS32030	COG4585	Histidine kinase
AOZ06_RS32035	COG2197	response regulator
AOZ06_RS32040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS32050	COG3104	oligopeptide transport
AOZ06_RS32055	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS32060	COG2329	Antibiotic biosynthesis monooxygenase
AOZ06_RS32110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOZ06_RS32115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOZ06_RS32130	COG2084	Dehydrogenase
AOZ06_RS32165	COG2226	methyltransferase
AOZ06_RS32165	COG2867	negative regulation of translational initiation
AOZ06_RS32170	COG0367	asparagine synthase
AOZ06_RS32175	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS32230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS32260	COG2124	cytochrome p450
AOZ06_RS32275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOZ06_RS32280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOZ06_RS32305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOZ06_RS32310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOZ06_RS32345	COG1742	UPF0060 membrane protein
AOZ06_RS32365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOZ06_RS32385	COG0564	pseudouridine synthase activity
AOZ06_RS32390	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS32465	COG1120	ATPase activity
AOZ06_RS32480	COG0484	heat shock protein binding
AOZ06_RS32515	COG3321	synthase
AOZ06_RS32515	COG0604	alcohol dehydrogenase
AOZ06_RS32520	COG0427	acetyl-CoA hydrolase
AOZ06_RS32530	COG0477	Major facilitator Superfamily
AOZ06_RS32545	COG1653	transport
AOZ06_RS32570	COG2197	response regulator
AOZ06_RS32580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOZ06_RS32585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS32590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS32645	COG2226	methyltransferase
AOZ06_RS32655	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AOZ06_RS32660	COG0028	Belongs to the TPP enzyme family
AOZ06_RS32665	COG0300	oxidoreductase activity
AOZ06_RS32685	COG2124	cytochrome p450
AOZ06_RS32690	COG1309	transcriptional regulator
AOZ06_RS32700	COG1309	transcriptional regulator
AOZ06_RS32730	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS32735	COG4566	intracellular signal transduction
AOZ06_RS32750	COG0243	molybdopterin cofactor binding
AOZ06_RS32825	COG0242	peptide deformylase activity
AOZ06_RS32830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ06_RS32840	COG0656	L-ascorbic acid biosynthetic process
AOZ06_RS32855	COG0596	Alpha beta hydrolase
AOZ06_RS32860	COG4977	sequence-specific DNA binding
AOZ06_RS32880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOZ06_RS32880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOZ06_RS32900	COG1716	ATPase activity
AOZ06_RS32905	COG0509	glycine decarboxylation via glycine cleavage system
AOZ06_RS32920	COG2814	Major facilitator Superfamily
AOZ06_RS32930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOZ06_RS32935	COG1024	Enoyl-CoA hydratase
AOZ06_RS32940	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOZ06_RS32950	COG1595	DNA-templated transcription, initiation
AOZ06_RS32995	COG0109	protoheme IX farnesyltransferase activity
AOZ06_RS33010	COG0673	inositol 2-dehydrogenase activity
AOZ06_RS33015	COG1879	ABC-type sugar transport system periplasmic component
AOZ06_RS33020	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS33025	COG1129	ABC transporter
AOZ06_RS33075	COG1940	carbohydrate kinase activity
AOZ06_RS33085	COG0492	ferredoxin-NADP+ reductase activity
AOZ06_RS33090	COG1396	sequence-specific DNA binding
AOZ06_RS33115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOZ06_RS33140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOZ06_RS33190	COG1024	Enoyl-CoA hydratase
AOZ06_RS33235	COG3537	Alpha-1,2-mannosidase
AOZ06_RS33240	COG1492	cobalamin metabolic process
AOZ06_RS33250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOZ06_RS33260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS33265	COG1695	Transcriptional regulator
AOZ06_RS33285	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS33315	COG3629	intracellular signal transduction
AOZ06_RS33315	COG3903	Transcriptional regulator
AOZ06_RS33330	COG1674	ftsk spoiiie
AOZ06_RS33365	COG3030	protein affecting phage T7 exclusion by the F plasmid
AOZ06_RS33385	COG2197	response regulator
AOZ06_RS33395	COG2409	Drug exporters of the RND superfamily
AOZ06_RS33400	COG2197	response regulator
AOZ06_RS33405	COG3851	Histidine kinase
AOZ06_RS33415	COG2234	aminopeptidase activity
AOZ06_RS33415	COG4935	Belongs to the peptidase S8 family
AOZ06_RS33460	COG1295	ribonuclease BN
AOZ06_RS33470	COG2208	phosphoserine phosphatase activity
AOZ06_RS33475	COG0784	Response regulator, receiver
AOZ06_RS33475	COG5002	protein histidine kinase activity
AOZ06_RS33500	COG1686	Belongs to the peptidase S11 family
AOZ06_RS33515	COG2409	Drug exporters of the RND superfamily
AOZ06_RS33525	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOZ06_RS33535	COG3226	Transcriptional regulator
AOZ06_RS33550	COG2815	serine threonine protein kinase
AOZ06_RS33550	COG0515	serine threonine protein kinase
AOZ06_RS33580	COG0018	arginyl-trna synthetase
AOZ06_RS33585	COG1397	ADP-ribosylglycohydrolase
AOZ06_RS33590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS33610	COG0577	efflux transmembrane transporter activity
AOZ06_RS33610	COG1136	(ABC) transporter
AOZ06_RS33615	COG0577	efflux transmembrane transporter activity
AOZ06_RS33615	COG1136	(ABC) transporter
AOZ06_RS33625	COG3250	beta-galactosidase activity
AOZ06_RS33630	COG0070	glutamate synthase
AOZ06_RS33630	COG0067	glutamate synthase
AOZ06_RS33630	COG0069	glutamate synthase activity
AOZ06_RS33655	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS33730	COG0045	succinate-CoA ligase (ADP-forming) activity
AOZ06_RS33775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ06_RS33795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOZ06_RS33820	COG0515	serine threonine protein kinase
AOZ06_RS33820	COG2815	serine threonine protein kinase
AOZ06_RS33855	COG0346	lactoylglutathione lyase activity
AOZ06_RS33865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOZ06_RS33875	COG0649	NAD binding
AOZ06_RS33880	COG1404	Belongs to the peptidase S8 family
AOZ06_RS33890	COG1007	ATP synthesis coupled electron transport
AOZ06_RS33900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOZ06_RS33905	COG0713	ATP synthesis coupled electron transport
AOZ06_RS33915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS33920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AOZ06_RS33925	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS33930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS33935	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS33945	COG3795	YCII-related domain
AOZ06_RS33955	COG3960	tartronate-semialdehyde synthase activity
AOZ06_RS33960	COG2084	Dehydrogenase
AOZ06_RS33965	COG3622	Belongs to the hyi family
AOZ06_RS33975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOZ06_RS33975	COG0723	plastoquinol--plastocyanin reductase activity
AOZ06_RS33980	COG2318	DinB family
AOZ06_RS34015	COG0706	membrane insertase activity
AOZ06_RS34030	COG1609	Transcriptional regulator
AOZ06_RS34060	COG0583	DNA-binding transcription factor activity
AOZ06_RS34070	COG0473	3-isopropylmalate dehydrogenase activity
AOZ06_RS34075	COG0583	DNA-binding transcription factor activity
AOZ06_RS34100	COG1609	Transcriptional regulator
AOZ06_RS34115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS34120	COG0626	cystathionine gamma-synthase activity
AOZ06_RS34125	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS34140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ06_RS34170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOZ06_RS34175	COG2807	transmembrane transport
AOZ06_RS34180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOZ06_RS34215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS34215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS34230	COG1408	metallophosphoesterase
AOZ06_RS34235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOZ06_RS34240	COG2226	methyltransferase
AOZ06_RS34250	COG2890	protein-(glutamine-N5) methyltransferase activity
AOZ06_RS34270	COG2124	cytochrome p450
AOZ06_RS34285	COG1280	lysine exporter protein (LysE YggA)
AOZ06_RS34290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS34295	COG1957	nucleoside hydrolase
AOZ06_RS34305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOZ06_RS34320	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS34350	COG2197	response regulator
AOZ06_RS34370	COG2814	Major facilitator Superfamily
AOZ06_RS34380	COG1522	sequence-specific DNA binding
AOZ06_RS34400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ06_RS34410	COG1120	ATPase activity
AOZ06_RS34415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS34420	COG2226	methyltransferase
AOZ06_RS34465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOZ06_RS34510	COG4608	Belongs to the ABC transporter superfamily
AOZ06_RS34525	COG4166	transmembrane transport
AOZ06_RS34530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS34555	COG1408	metallophosphoesterase
AOZ06_RS34580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOZ06_RS34595	COG3629	intracellular signal transduction
AOZ06_RS34595	COG3903	Transcriptional regulator
AOZ06_RS34600	COG1129	ABC transporter
AOZ06_RS34605	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS34655	COG2226	methyltransferase
AOZ06_RS34685	COG2814	Major facilitator Superfamily
AOZ06_RS34690	COG1733	regulation of RNA biosynthetic process
AOZ06_RS34705	COG3383	formate dehydrogenase (NAD+) activity
AOZ06_RS34705	COG0243	molybdopterin cofactor binding
AOZ06_RS34710	COG3383	formate dehydrogenase (NAD+) activity
AOZ06_RS34710	COG0243	molybdopterin cofactor binding
AOZ06_RS34715	COG0437	4 iron, 4 sulfur cluster binding
AOZ06_RS34725	COG0028	Belongs to the TPP enzyme family
AOZ06_RS34735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS34810	COG1660	Displays ATPase and GTPase activities
AOZ06_RS34820	COG1316	TRANSCRIPTIONal
AOZ06_RS34830	COG5416	Lipopolysaccharide assembly protein A domain
AOZ06_RS34840	COG0640	Transcriptional regulator
AOZ06_RS34860	COG4585	Histidine kinase
AOZ06_RS34865	COG2197	response regulator
AOZ06_RS34875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOZ06_RS34895	COG3550	peptidyl-serine autophosphorylation
AOZ06_RS34905	COG1522	sequence-specific DNA binding
AOZ06_RS34910	COG1404	Belongs to the peptidase S8 family
AOZ06_RS34930	COG1309	transcriptional regulator
AOZ06_RS34945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOZ06_RS34960	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS34980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AOZ06_RS34985	COG0784	Response regulator, receiver
AOZ06_RS34990	COG4251	negative regulation of phosphorylation
AOZ06_RS34995	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS35050	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOZ06_RS35075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOZ06_RS35080	COG2963	transposase activity
AOZ06_RS35085	COG2801	Transposase and inactivated derivatives
AOZ06_RS35145	COG4585	Histidine kinase
AOZ06_RS35150	COG2197	response regulator
AOZ06_RS35155	COG0596	Alpha beta hydrolase
AOZ06_RS35165	COG1846	Transcriptional regulator
AOZ06_RS35195	COG1921	L-seryl-tRNASec selenium transferase activity
AOZ06_RS35225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ06_RS35230	COG1349	DNA-binding transcription factor activity
AOZ06_RS35235	COG1105	Belongs to the carbohydrate kinase PfkB family
AOZ06_RS35250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ06_RS35250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ06_RS35255	COG1063	alcohol dehydrogenase
AOZ06_RS35265	COG0656	L-ascorbic acid biosynthetic process
AOZ06_RS35300	COG1959	2 iron, 2 sulfur cluster binding
AOZ06_RS35315	COG0714	Associated with various cellular activities
AOZ06_RS35395	COG0583	DNA-binding transcription factor activity
AOZ06_RS35415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOZ06_RS35485	COG2814	Major facilitator Superfamily
AOZ06_RS35500	COG3254	rhamnose metabolic process
AOZ06_RS35505	COG4214	carbohydrate transport
AOZ06_RS35510	COG1129	ABC transporter
AOZ06_RS35520	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS35525	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS35555	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AOZ06_RS35580	COG1703	isobutyryl-CoA mutase activity
AOZ06_RS35580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOZ06_RS35580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOZ06_RS35595	COG4279	zinc finger
AOZ06_RS35600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOZ06_RS35635	COG1136	(ABC) transporter
AOZ06_RS35670	COG1846	Transcriptional regulator
AOZ06_RS35680	COG3469	chitinase activity
AOZ06_RS35690	COG1309	transcriptional regulator
AOZ06_RS35735	COG0174	glutamine synthetase
AOZ06_RS35740	COG4689	acetoacetate decarboxylase
AOZ06_RS35755	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOZ06_RS35765	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS35770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AOZ06_RS35780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AOZ06_RS35790	COG0463	Glycosyl transferase, family 2
AOZ06_RS35795	COG2205	protein histidine kinase activity
AOZ06_RS35800	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS35830	COG0459	protein refolding
AOZ06_RS35855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOZ06_RS35880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS35895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS35905	COG4166	transmembrane transport
AOZ06_RS35910	COG0601	transmembrane transport
AOZ06_RS35915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS35925	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS35930	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS35935	COG3845	ABC transporter
AOZ06_RS35970	COG3629	intracellular signal transduction
AOZ06_RS35970	COG3903	Transcriptional regulator
AOZ06_RS36000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS36010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS36020	COG3279	Response regulator of the LytR AlgR family
AOZ06_RS36025	COG3275	phosphorelay sensor kinase activity
AOZ06_RS36035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOZ06_RS36040	COG1401	restriction endodeoxyribonuclease activity
AOZ06_RS36050	COG0017	Asparaginyl-tRNA synthetase
AOZ06_RS36075	COG0506	proline dehydrogenase activity
AOZ06_RS36080	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS36095	COG2188	Transcriptional regulator
AOZ06_RS36120	COG1309	transcriptional regulator
AOZ06_RS36140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ06_RS36155	COG2151	metal-sulfur cluster biosynthetic enzyme
AOZ06_RS36160	COG0822	iron-sulfur transferase activity
AOZ06_RS36170	COG0396	ATPase activity
AOZ06_RS36220	COG1522	sequence-specific DNA binding
AOZ06_RS36230	COG1131	(ABC) transporter
AOZ06_RS36250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOZ06_RS36290	COG2133	pyrroloquinoline quinone binding
AOZ06_RS36295	COG0109	protoheme IX farnesyltransferase activity
AOZ06_RS36305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOZ06_RS36335	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS36360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOZ06_RS36365	COG0542	response to heat
AOZ06_RS36370	COG0252	asparaginase activity
AOZ06_RS36375	COG0363	glucosamine-6-phosphate deaminase activity
AOZ06_RS36380	COG0515	serine threonine protein kinase
AOZ06_RS36380	COG2815	serine threonine protein kinase
AOZ06_RS36385	COG0584	glycerophosphoryl diester phosphodiesterase
AOZ06_RS36415	COG1132	(ABC) transporter
AOZ06_RS36435	COG0149	triose-phosphate isomerase activity
AOZ06_RS36440	COG0126	phosphoglycerate kinase activity
AOZ06_RS36465	COG1481	regulation of sporulation
AOZ06_RS36475	COG1660	Displays ATPase and GTPase activities
AOZ06_RS36480	COG0322	excinuclease ABC activity
AOZ06_RS36515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOZ06_RS36520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOZ06_RS36520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOZ06_RS36560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOZ06_RS36565	COG0242	peptide deformylase activity
AOZ06_RS36595	COG0405	Gamma-glutamyltransferase
AOZ06_RS36600	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS36605	COG0028	Belongs to the TPP enzyme family
AOZ06_RS36615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS36655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOZ06_RS36660	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOZ06_RS36670	COG1758	RNA polymerase activity
AOZ06_RS36685	COG0284	orotidine-5'-phosphate decarboxylase activity
AOZ06_RS36695	COG0505	Belongs to the CarA family
AOZ06_RS36710	COG0540	Belongs to the ATCase OTCase family
AOZ06_RS36715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AOZ06_RS36730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOZ06_RS36735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOZ06_RS36740	COG0006	proline dipeptidase activity
AOZ06_RS36760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOZ06_RS36765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOZ06_RS36770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOZ06_RS36775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOZ06_RS36800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS36810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOZ06_RS36815	COG1263	PTS System
AOZ06_RS36830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOZ06_RS36845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOZ06_RS36905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOZ06_RS36920	COG1126	abc transporter atp-binding protein
AOZ06_RS36925	COG0765	amino acid transport
AOZ06_RS36970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOZ06_RS36990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOZ06_RS36995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOZ06_RS37000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOZ06_RS37015	COG2255	four-way junction helicase activity
AOZ06_RS37020	COG0632	four-way junction helicase activity
AOZ06_RS37035	COG0475	glutathione-regulated potassium exporter activity
AOZ06_RS37050	COG2072	flavoprotein involved in K transport
AOZ06_RS37060	COG0217	transcriptional regulatory protein
AOZ06_RS37075	COG1309	transcriptional regulator
AOZ06_RS37085	COG3629	intracellular signal transduction
AOZ06_RS37085	COG3903	Transcriptional regulator
AOZ06_RS37095	COG1309	transcriptional regulator
AOZ06_RS37100	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AOZ06_RS37110	COG1051	belongs to the nudix hydrolase family
AOZ06_RS37115	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS37125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOZ06_RS37145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOZ06_RS37165	COG1131	(ABC) transporter
AOZ06_RS37200	COG1733	regulation of RNA biosynthetic process
AOZ06_RS37270	COG0640	Transcriptional regulator
AOZ06_RS37300	COG1609	Transcriptional regulator
AOZ06_RS37315	COG0559	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS37380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ06_RS37390	COG0702	epimerase
AOZ06_RS37395	COG3304	Inner membrane component domain
AOZ06_RS37405	COG2124	cytochrome p450
AOZ06_RS37430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ06_RS37440	COG2264	protein methyltransferase activity
AOZ06_RS37445	COG1366	Belongs to the anti-sigma-factor antagonist family
AOZ06_RS37450	COG1366	Belongs to the anti-sigma-factor antagonist family
AOZ06_RS37455	COG2172	sigma factor antagonist activity
AOZ06_RS37465	COG2208	phosphoserine phosphatase activity
AOZ06_RS37475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOZ06_RS37480	COG2011	ABC-type metal ion transport system permease component
AOZ06_RS37490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ06_RS37500	COG1252	NADH dehydrogenase
AOZ06_RS37505	COG1595	DNA-templated transcription, initiation
AOZ06_RS37550	COG2197	response regulator
AOZ06_RS37565	COG0667	Aldo Keto reductase
AOZ06_RS37575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AOZ06_RS37595	COG2814	Major facilitator Superfamily
AOZ06_RS37630	COG2375	cellular response to nickel ion
AOZ06_RS37650	COG3629	intracellular signal transduction
AOZ06_RS37650	COG3903	Transcriptional regulator
AOZ06_RS37655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOZ06_RS37685	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOZ06_RS37690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS37705	COG1309	transcriptional regulator
AOZ06_RS37765	COG0515	serine threonine protein kinase
AOZ06_RS37785	COG1174	glycine betaine transport
AOZ06_RS37795	COG1174	glycine betaine transport
AOZ06_RS37810	COG1129	ABC transporter
AOZ06_RS37845	COG3903	Transcriptional regulator
AOZ06_RS37845	COG3629	intracellular signal transduction
AOZ06_RS37855	COG0488	(ABC) transporter
AOZ06_RS37870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS37915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOZ06_RS37945	COG1073	alpha beta
AOZ06_RS37965	COG2801	Transposase and inactivated derivatives
AOZ06_RS37965	COG3415	Transposase
AOZ06_RS37980	COG0702	epimerase
AOZ06_RS37985	COG1793	dna ligase
AOZ06_RS37985	COG3285	dna ligase
AOZ06_RS37995	COG1309	transcriptional regulator
AOZ06_RS38005	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS38030	COG0596	Alpha beta hydrolase
AOZ06_RS38035	COG0439	Biotin carboxylase
AOZ06_RS38040	COG3979	chitinase
AOZ06_RS38065	COG2366	antibiotic biosynthetic process
AOZ06_RS38080	COG4585	Histidine kinase
AOZ06_RS38085	COG2197	response regulator
AOZ06_RS38115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS38120	COG0154	amidase activity
AOZ06_RS38130	COG1609	Transcriptional regulator
AOZ06_RS38135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOZ06_RS38150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS38190	COG2226	methyltransferase
AOZ06_RS38200	COG3903	Transcriptional regulator
AOZ06_RS38200	COG3629	intracellular signal transduction
AOZ06_RS38230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOZ06_RS38275	COG3250	beta-galactosidase activity
AOZ06_RS38295	COG0702	epimerase
AOZ06_RS38305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOZ06_RS38310	COG3250	beta-galactosidase activity
AOZ06_RS38350	COG2814	Major facilitator Superfamily
AOZ06_RS38355	COG1595	DNA-templated transcription, initiation
AOZ06_RS38360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ06_RS38365	COG0583	DNA-binding transcription factor activity
AOZ06_RS38380	COG1228	amidohydrolase
AOZ06_RS38390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ06_RS38400	COG2133	pyrroloquinoline quinone binding
AOZ06_RS38400	COG5183	chlorophyll binding
AOZ06_RS38415	COG2409	Drug exporters of the RND superfamily
AOZ06_RS38450	COG1404	Belongs to the peptidase S8 family
AOZ06_RS38495	COG2197	response regulator
AOZ06_RS38505	COG0604	alcohol dehydrogenase
AOZ06_RS38535	COG0402	S-adenosylhomocysteine deaminase activity
AOZ06_RS38540	COG2271	Major facilitator Superfamily
AOZ06_RS38560	COG4948	Mandelate Racemase Muconate Lactonizing
AOZ06_RS38570	COG3835	regulator
AOZ06_RS38605	COG0277	FAD linked oxidase domain protein
AOZ06_RS38625	COG3629	intracellular signal transduction
AOZ06_RS38630	COG3629	intracellular signal transduction
AOZ06_RS38630	COG3903	Transcriptional regulator
AOZ06_RS38635	COG2197	response regulator
AOZ06_RS38655	COG0484	heat shock protein binding
AOZ06_RS38670	COG0464	growth
AOZ06_RS38690	COG1674	ftsk spoiiie
AOZ06_RS38720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOZ06_RS38755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ06_RS38765	COG3226	Transcriptional regulator
AOZ06_RS38775	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ06_RS38785	COG2197	response regulator
AOZ06_RS38790	COG4585	Histidine kinase
AOZ06_RS38805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOZ06_RS38815	COG0596	Alpha beta hydrolase
AOZ06_RS38845	COG3903	Transcriptional regulator
AOZ06_RS38845	COG3629	intracellular signal transduction
AOZ06_RS38875	COG1022	Amp-dependent synthetase and ligase
AOZ06_RS38905	COG0477	Major facilitator Superfamily
AOZ06_RS38910	COG1234	tRNA 3'-trailer cleavage
AOZ06_RS38925	COG2807	transmembrane transport
AOZ06_RS39005	COG4585	Histidine kinase
AOZ06_RS39010	COG2197	response regulator
AOZ06_RS39020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOZ06_RS39045	COG1278	Cold shock
AOZ06_RS39070	COG0583	DNA-binding transcription factor activity
AOZ06_RS39115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS39160	COG1595	DNA-templated transcription, initiation
AOZ06_RS39230	COG0577	efflux transmembrane transporter activity
AOZ06_RS39230	COG1136	(ABC) transporter
AOZ06_RS39280	COG0515	serine threonine protein kinase
AOZ06_RS39315	COG2201	protein-glutamate methylesterase activity
AOZ06_RS39325	COG2201	protein-glutamate methylesterase activity
AOZ06_RS39330	COG0753	catalase activity
AOZ06_RS39330	COG0693	protein deglycase activity
AOZ06_RS39340	COG4106	trans-aconitate 2-methyltransferase activity
AOZ06_RS39350	COG3263	regulation of cellular component size
AOZ06_RS39380	COG1732	Glycine betaine
AOZ06_RS39385	COG1174	glycine betaine transport
AOZ06_RS39400	COG0477	Major facilitator Superfamily
AOZ06_RS39425	COG0714	Associated with various cellular activities
AOZ06_RS39430	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AOZ06_RS39450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOZ06_RS39455	COG2124	cytochrome p450
AOZ06_RS39460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS39470	COG0515	serine threonine protein kinase
AOZ06_RS39470	COG2815	serine threonine protein kinase
AOZ06_RS39505	COG2814	Major facilitator Superfamily
AOZ06_RS39520	COG3629	intracellular signal transduction
AOZ06_RS39520	COG3903	Transcriptional regulator
AOZ06_RS39525	COG0596	Alpha beta hydrolase
AOZ06_RS39555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS39570	COG2226	methyltransferase
AOZ06_RS39575	COG1309	transcriptional regulator
AOZ06_RS39580	COG2267	carboxylic ester hydrolase activity
AOZ06_RS39595	COG0583	DNA-binding transcription factor activity
AOZ06_RS39640	COG3321	synthase
AOZ06_RS39640	COG0604	alcohol dehydrogenase
AOZ06_RS39655	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ06_RS39665	COG3629	intracellular signal transduction
AOZ06_RS39665	COG3903	Transcriptional regulator
AOZ06_RS39680	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS39740	COG2936	dipeptidyl-peptidase activity
AOZ06_RS39745	COG2205	protein histidine kinase activity
AOZ06_RS39750	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS39765	COG1136	(ABC) transporter
AOZ06_RS39765	COG0577	efflux transmembrane transporter activity
AOZ06_RS39770	COG0577	efflux transmembrane transporter activity
AOZ06_RS39770	COG1136	(ABC) transporter
AOZ06_RS39780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ06_RS39825	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOZ06_RS39865	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS39870	COG1175	transmembrane transport
AOZ06_RS39875	COG3345	alpha-galactosidase
AOZ06_RS39880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AOZ06_RS39885	COG0457	Tetratricopeptide repeat
AOZ06_RS39890	COG2207	Transcriptional regulator
AOZ06_RS39915	COG3842	ATPase activity
AOZ06_RS39930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ06_RS39960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOZ06_RS39965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOZ06_RS39970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOZ06_RS39970	COG0473	3-isopropylmalate dehydrogenase activity
AOZ06_RS39975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOZ06_RS39980	COG3384	dioxygenase
AOZ06_RS39985	COG2159	amidohydrolase
AOZ06_RS39990	COG2368	4-hydroxyphenylacetate
AOZ06_RS40005	COG2186	Transcriptional regulator
AOZ06_RS40010	COG2807	transmembrane transport
AOZ06_RS40035	COG3706	GGDEF domain
AOZ06_RS40195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AOZ06_RS40260	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS40265	COG2205	protein histidine kinase activity
AOZ06_RS40290	COG0583	DNA-binding transcription factor activity
AOZ06_RS40310	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS40335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS40335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS40340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOZ06_RS40360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOZ06_RS40390	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS40410	COG1309	transcriptional regulator
AOZ06_RS40415	COG1595	DNA-templated transcription, initiation
AOZ06_RS40425	COG1131	(ABC) transporter
AOZ06_RS40450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOZ06_RS40450	COG0072	phenylalanine-tRNA ligase activity
AOZ06_RS40455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOZ06_RS40460	COG0326	Molecular chaperone. Has ATPase activity
AOZ06_RS40485	COG1404	Belongs to the peptidase S8 family
AOZ06_RS40490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ06_RS40495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOZ06_RS40500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AOZ06_RS40535	COG1414	Transcriptional regulator
AOZ06_RS40540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS40555	COG1414	Transcriptional regulator
AOZ06_RS40570	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AOZ06_RS40575	COG0800	Aldolase
AOZ06_RS40580	COG2610	gluconate transmembrane transporter activity
AOZ06_RS40585	COG2706	6-phosphogluconolactonase activity
AOZ06_RS40595	COG1175	transmembrane transport
AOZ06_RS40600	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS40605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AOZ06_RS40610	COG4565	transcriptional regulatory protein
AOZ06_RS40615	COG3290	protein histidine kinase activity
AOZ06_RS40620	COG1301	dicarboxylic acid transport
AOZ06_RS40625	COG3903	Transcriptional regulator
AOZ06_RS40625	COG3629	intracellular signal transduction
AOZ06_RS40630	COG1053	succinate dehydrogenase
AOZ06_RS40630	COG3976	FMN-binding domain protein
AOZ06_RS40630	COG0431	NADPH-dependent FMN reductase
AOZ06_RS40650	COG1492	cobalamin metabolic process
AOZ06_RS40665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS40690	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AOZ06_RS40695	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AOZ06_RS40735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOZ06_RS40785	COG1487	ribonuclease activity
AOZ06_RS40840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS40885	COG2318	DinB family
AOZ06_RS40895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS40905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS40910	COG0328	RNA-DNA hybrid ribonuclease activity
AOZ06_RS40915	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS40940	COG0583	DNA-binding transcription factor activity
AOZ06_RS40965	COG2267	carboxylic ester hydrolase activity
AOZ06_RS40970	COG0583	DNA-binding transcription factor activity
AOZ06_RS40975	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS41020	COG0477	Major facilitator Superfamily
AOZ06_RS41035	COG0297	glycogen (starch) synthase activity
AOZ06_RS41055	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOZ06_RS41075	COG1070	Carbohydrate kinase
AOZ06_RS41085	COG1609	Transcriptional regulator
AOZ06_RS41095	COG1879	ABC-type sugar transport system periplasmic component
AOZ06_RS41100	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS41105	COG1129	ABC transporter
AOZ06_RS41125	COG4946	Tricorn protease homolog
AOZ06_RS41125	COG1506	peptidase
AOZ06_RS41125	COG0823	Involved in the tonB-independent uptake of proteins
AOZ06_RS41135	COG1131	(ABC) transporter
AOZ06_RS41150	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AOZ06_RS41180	COG1595	DNA-templated transcription, initiation
AOZ06_RS41185	COG0702	epimerase
AOZ06_RS41200	COG0137	argininosuccinate synthase activity
AOZ06_RS41235	COG2182	Extracellular solute-binding protein
AOZ06_RS41240	COG1175	transmembrane transport
AOZ06_RS41245	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS41250	COG1472	Belongs to the glycosyl hydrolase 3 family
AOZ06_RS41255	COG0237	dephospho-CoA kinase activity
AOZ06_RS41255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOZ06_RS41270	COG0539	negative regulation of cytoplasmic translation
AOZ06_RS41275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS41290	COG2197	response regulator
AOZ06_RS41295	COG4585	Histidine kinase
AOZ06_RS41310	COG3706	GGDEF domain
AOZ06_RS41325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOZ06_RS41330	COG1511	domain protein
AOZ06_RS41350	COG0778	Nitroreductase
AOZ06_RS41385	COG2050	protein possibly involved in aromatic compounds catabolism
AOZ06_RS41390	COG0583	DNA-binding transcription factor activity
AOZ06_RS41475	COG2801	Transposase and inactivated derivatives
AOZ06_RS41500	COG3903	Transcriptional regulator
AOZ06_RS41500	COG3629	intracellular signal transduction
AOZ06_RS41505	COG3629	intracellular signal transduction
AOZ06_RS41505	COG3903	Transcriptional regulator
AOZ06_RS41550	COG2986	histidine ammonia-lyase
AOZ06_RS41575	COG2175	clavaminate synthase activity
AOZ06_RS41585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS41595	COG4566	intracellular signal transduction
AOZ06_RS41620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOZ06_RS41620	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AOZ06_RS41635	COG3226	Transcriptional regulator
AOZ06_RS41640	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS41685	COG0235	Class ii aldolase
AOZ06_RS41690	COG3395	kinase activity
AOZ06_RS41700	COG3622	Belongs to the hyi family
AOZ06_RS41705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOZ06_RS41770	COG1124	(ABC) transporter
AOZ06_RS41775	COG0444	Belongs to the ABC transporter superfamily
AOZ06_RS41780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS41785	COG0601	transmembrane transport
AOZ06_RS41795	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AOZ06_RS41830	COG3629	intracellular signal transduction
AOZ06_RS41830	COG3903	Transcriptional regulator
AOZ06_RS41835	COG3629	intracellular signal transduction
AOZ06_RS41835	COG3903	Transcriptional regulator
AOZ06_RS41855	COG2826	transposase and inactivated derivatives, IS30 family
AOZ06_RS41895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOZ06_RS41900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ06_RS41920	COG2814	Major facilitator Superfamily
AOZ06_RS41925	COG0640	Transcriptional regulator
AOZ06_RS41930	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS41945	COG3903	Transcriptional regulator
AOZ06_RS41945	COG3629	intracellular signal transduction
AOZ06_RS41950	COG2197	response regulator
AOZ06_RS41960	COG2188	Transcriptional regulator
AOZ06_RS41985	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS42000	COG0009	L-threonylcarbamoyladenylate synthase
AOZ06_RS42005	COG2132	Multicopper oxidase
AOZ06_RS42050	COG0134	indole-3-glycerol-phosphate synthase activity
AOZ06_RS42055	COG0135	phosphoribosylanthranilate isomerase activity
AOZ06_RS42060	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42065	COG0662	Cupin 2, conserved barrel domain protein
AOZ06_RS42070	COG0159	tryptophan synthase activity
AOZ06_RS42075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOZ06_RS42095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOZ06_RS42100	COG3903	Transcriptional regulator
AOZ06_RS42100	COG3629	intracellular signal transduction
AOZ06_RS42105	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS42110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOZ06_RS42120	COG2072	flavoprotein involved in K transport
AOZ06_RS42140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOZ06_RS42150	COG4585	Histidine kinase
AOZ06_RS42155	COG2197	response regulator
AOZ06_RS42170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOZ06_RS42175	COG0156	8-amino-7-oxononanoate synthase activity
AOZ06_RS42180	COG0514	ATP-dependent DNA helicase (RecQ)
AOZ06_RS42190	COG2133	pyrroloquinoline quinone binding
AOZ06_RS42200	COG2267	carboxylic ester hydrolase activity
AOZ06_RS42235	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOZ06_RS42240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOZ06_RS42250	COG2723	6-phospho-beta-galactosidase activity
AOZ06_RS42260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS42265	COG0601	transmembrane transport
AOZ06_RS42275	COG0747	negative chemotaxis
AOZ06_RS42280	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS42295	COG1940	carbohydrate kinase activity
AOZ06_RS42300	COG1940	carbohydrate kinase activity
AOZ06_RS42300	COG1846	Transcriptional regulator
AOZ06_RS42330	COG1132	(ABC) transporter
AOZ06_RS42335	COG1132	(ABC) transporter
AOZ06_RS42340	COG0515	serine threonine protein kinase
AOZ06_RS42345	COG4106	trans-aconitate 2-methyltransferase activity
AOZ06_RS42350	COG1846	Transcriptional regulator
AOZ06_RS42355	COG1764	response to oxidative stress
AOZ06_RS42360	COG0277	FAD linked oxidase domain protein
AOZ06_RS42365	COG3485	protocatechuate 3,4-dioxygenase
AOZ06_RS42370	COG3485	protocatechuate 3,4-dioxygenase
AOZ06_RS42380	COG1414	Transcriptional regulator
AOZ06_RS42385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOZ06_RS42390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOZ06_RS42400	COG1414	Transcriptional regulator
AOZ06_RS42445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOZ06_RS42465	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42470	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42480	COG2070	2-Nitropropane dioxygenase
AOZ06_RS42490	COG1024	Enoyl-CoA hydratase
AOZ06_RS42515	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS42520	COG2124	cytochrome p450
AOZ06_RS42525	COG0183	Belongs to the thiolase family
AOZ06_RS42535	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS42595	COG3385	transposase activity
AOZ06_RS42660	COG3629	intracellular signal transduction
AOZ06_RS42660	COG3903	Transcriptional regulator
AOZ06_RS42685	COG0183	Belongs to the thiolase family
AOZ06_RS42690	COG1309	transcriptional regulator
AOZ06_RS42700	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42705	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS42710	COG1024	Enoyl-CoA hydratase
AOZ06_RS42715	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42720	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ06_RS42765	COG0515	serine threonine protein kinase
AOZ06_RS42765	COG2815	serine threonine protein kinase
AOZ06_RS42770	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOZ06_RS42780	COG0346	lactoylglutathione lyase activity
AOZ06_RS42785	COG2267	carboxylic ester hydrolase activity
AOZ06_RS42790	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42800	COG2181	nitrate reductase activity
AOZ06_RS42800	COG0247	lactate metabolic process
AOZ06_RS42810	COG2409	Drug exporters of the RND superfamily
AOZ06_RS42820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ06_RS42825	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AOZ06_RS42830	COG3971	2-oxopent-4-enoate hydratase activity
AOZ06_RS42840	COG1053	succinate dehydrogenase
AOZ06_RS42860	COG2030	dehydratase
AOZ06_RS42885	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42890	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42895	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42900	COG1309	transcriptional regulator
AOZ06_RS42905	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS42930	COG2301	Belongs to the HpcH HpaI aldolase family
AOZ06_RS42935	COG2301	Belongs to the HpcH HpaI aldolase family
AOZ06_RS42945	COG1446	asparaginase
AOZ06_RS42975	COG2018	Roadblock/LC7 domain
AOZ06_RS42990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOZ06_RS43000	COG2211	Major facilitator Superfamily
AOZ06_RS43005	COG0431	NADPH-dependent FMN reductase
AOZ06_RS43025	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AOZ06_RS43115	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS43140	COG2197	response regulator
AOZ06_RS43180	COG1136	(ABC) transporter
AOZ06_RS43185	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS43185	COG1672	PFAM Archaeal ATPase
AOZ06_RS43210	COG0288	reversible hydration of carbon dioxide
AOZ06_RS43215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOZ06_RS43220	COG1946	Acyl-CoA thioesterase
AOZ06_RS43265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOZ06_RS43280	COG2986	histidine ammonia-lyase
AOZ06_RS43290	COG0070	glutamate synthase
AOZ06_RS43290	COG0069	glutamate synthase activity
AOZ06_RS43290	COG0067	glutamate synthase
AOZ06_RS43295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOZ06_RS43300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOZ06_RS43305	COG1120	ATPase activity
AOZ06_RS43330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOZ06_RS43335	COG0159	tryptophan synthase activity
AOZ06_RS43340	COG0133	tryptophan synthase activity
AOZ06_RS43345	COG0134	indole-3-glycerol-phosphate synthase activity
AOZ06_RS43355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOZ06_RS43380	COG0107	imidazoleglycerol-phosphate synthase activity
AOZ06_RS43405	COG1131	(ABC) transporter
AOZ06_RS43415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOZ06_RS43425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOZ06_RS43440	COG0131	Imidazoleglycerol-phosphate dehydratase
AOZ06_RS43445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOZ06_RS43450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOZ06_RS43465	COG0640	Transcriptional regulator
AOZ06_RS43470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOZ06_RS43475	COG0747	negative chemotaxis
AOZ06_RS43485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOZ06_RS43490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOZ06_RS43510	COG0477	Major facilitator Superfamily
AOZ06_RS43530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOZ06_RS43535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AOZ06_RS43540	COG1609	Transcriptional regulator
AOZ06_RS43545	COG0673	inositol 2-dehydrogenase activity
AOZ06_RS43560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ06_RS43580	COG3979	chitinase
AOZ06_RS43585	COG3842	ATPase activity
AOZ06_RS43590	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS43600	COG2182	Extracellular solute-binding protein
AOZ06_RS43635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOZ06_RS43645	COG1872	DUF167
AOZ06_RS43660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOZ06_RS43670	COG3599	regulation of cell shape
AOZ06_RS43680	COG1799	cell septum assembly
AOZ06_RS43685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOZ06_RS43700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOZ06_RS43705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOZ06_RS43710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOZ06_RS43720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOZ06_RS43725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOZ06_RS43750	COG0275	rRNA processing
AOZ06_RS43755	COG2001	Belongs to the MraZ family
AOZ06_RS43760	COG0714	Associated with various cellular activities
AOZ06_RS43770	COG1305	Transglutaminase-like
AOZ06_RS43785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS43800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOZ06_RS43820	COG1192	Involved in chromosome partitioning
AOZ06_RS43825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOZ06_RS43830	COG0167	dihydroorotate dehydrogenase activity
AOZ06_RS43835	COG2233	PERMEase
AOZ06_RS43845	COG1842	Phage shock protein A
AOZ06_RS43850	COG1396	sequence-specific DNA binding
AOZ06_RS43855	COG1058	Belongs to the CinA family
AOZ06_RS43855	COG1546	Belongs to the CinA family
AOZ06_RS43865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOZ06_RS43870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AOZ06_RS43945	COG3451	type IV secretory pathway VirB4
AOZ06_RS43955	COG1674	ftsk spoiiie
AOZ06_RS43985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOZ06_RS43990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOZ06_RS44000	COG0515	serine threonine protein kinase
AOZ06_RS44005	COG0515	serine threonine protein kinase
AOZ06_RS44015	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AOZ06_RS44030	COG3214	Protein conserved in bacteria
AOZ06_RS44035	COG1247	-acetyltransferase
AOZ06_RS44045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS44050	COG0697	spore germination
AOZ06_RS44075	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS44080	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS44085	COG1129	ABC transporter
AOZ06_RS44090	COG1879	ABC-type sugar transport system periplasmic component
AOZ06_RS44095	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS44100	COG2205	protein histidine kinase activity
AOZ06_RS44140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOZ06_RS44150	COG1185	polyribonucleotide nucleotidyltransferase activity
AOZ06_RS44155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AOZ06_RS44165	COG4585	Histidine kinase
AOZ06_RS44170	COG2197	response regulator
AOZ06_RS44190	COG0702	epimerase
AOZ06_RS44215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOZ06_RS44240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AOZ06_RS44250	COG0640	Transcriptional regulator
AOZ06_RS44255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOZ06_RS44260	COG0346	lactoylglutathione lyase activity
AOZ06_RS44265	COG1132	(ABC) transporter
AOZ06_RS44275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AOZ06_RS44295	COG0779	Required for maturation of 30S ribosomal subunits
AOZ06_RS44320	COG0432	Pfam Uncharacterised protein family UPF0047
AOZ06_RS44350	COG0442	prolyl-tRNA aminoacylation
AOZ06_RS44355	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS44355	COG3347	Dehydrogenase
AOZ06_RS44360	COG0235	Class ii aldolase
AOZ06_RS44360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AOZ06_RS44370	COG3022	response to hydroperoxide
AOZ06_RS44375	COG0513	Belongs to the DEAD box helicase family
AOZ06_RS44380	COG1648	precorrin-2 dehydrogenase activity
AOZ06_RS44380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOZ06_RS44400	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS44410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOZ06_RS44420	COG0156	8-amino-7-oxononanoate synthase activity
AOZ06_RS44445	COG1881	PFAM PEBP family protein
AOZ06_RS44455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOZ06_RS44470	COG1643	Atp-dependent helicase
AOZ06_RS44475	COG2186	Transcriptional regulator
AOZ06_RS44500	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOZ06_RS44510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOZ06_RS44545	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOZ06_RS44580	COG1136	(ABC) transporter
AOZ06_RS44580	COG0577	efflux transmembrane transporter activity
AOZ06_RS44585	COG1136	(ABC) transporter
AOZ06_RS44585	COG0577	efflux transmembrane transporter activity
AOZ06_RS44600	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS44605	COG2205	protein histidine kinase activity
AOZ06_RS44610	COG1695	Transcriptional regulator
AOZ06_RS44630	COG0575	Belongs to the CDS family
AOZ06_RS44640	COG0528	UMP kinase activity
AOZ06_RS44645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AOZ06_RS44650	COG0052	Belongs to the universal ribosomal protein uS2 family
AOZ06_RS44660	COG1309	transcriptional regulator
AOZ06_RS44670	COG1191	sigma factor activity
AOZ06_RS44710	COG0792	nuclease activity
AOZ06_RS44715	COG0596	Alpha beta hydrolase
AOZ06_RS44725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOZ06_RS44735	COG0335	large ribosomal subunit rRNA binding
AOZ06_RS44740	COG0336	Belongs to the RNA methyltransferase TrmD family
AOZ06_RS44745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOZ06_RS44760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOZ06_RS44790	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AOZ06_RS44805	COG2226	methyltransferase
AOZ06_RS44820	COG1832	CoA-binding protein
AOZ06_RS44830	COG4266	Belongs to the allantoicase family
AOZ06_RS44835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOZ06_RS44870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOZ06_RS44880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOZ06_RS44885	COG1414	Transcriptional regulator
AOZ06_RS44910	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOZ06_RS44925	COG2353	YceI-like domain
AOZ06_RS44950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS44955	COG0596	Alpha beta hydrolase
AOZ06_RS44975	COG1254	Belongs to the acylphosphatase family
AOZ06_RS45015	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AOZ06_RS45020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOZ06_RS45025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOZ06_RS45035	COG0367	asparagine synthase
AOZ06_RS45050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOZ06_RS45055	COG0571	ribonuclease III activity
AOZ06_RS45060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOZ06_RS45090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOZ06_RS45095	COG0742	ribosomal rna small subunit methyltransferase
AOZ06_RS45105	COG3973	AAA domain
AOZ06_RS45115	COG0010	Belongs to the arginase family
AOZ06_RS45145	COG1461	Dihydroxyacetone kinase
AOZ06_RS45150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOZ06_RS45160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOZ06_RS45165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AOZ06_RS45170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOZ06_RS45195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS45210	COG0626	cystathionine gamma-synthase activity
AOZ06_RS45215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOZ06_RS45225	COG1920	GTP binding
AOZ06_RS45235	COG0494	nUDIX hydrolase
AOZ06_RS45235	COG0406	alpha-ribazole phosphatase activity
AOZ06_RS45245	COG0066	3-isopropylmalate dehydratase activity
AOZ06_RS45250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOZ06_RS45270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOZ06_RS45280	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOZ06_RS45305	COG2936	dipeptidyl-peptidase activity
AOZ06_RS45310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ06_RS45315	COG0473	3-isopropylmalate dehydrogenase activity
AOZ06_RS45320	COG1404	Belongs to the peptidase S8 family
AOZ06_RS45335	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOZ06_RS45340	COG0440	acetolactate synthase activity
AOZ06_RS45355	COG0129	dihydroxy-acid dehydratase activity
AOZ06_RS45370	COG2259	Doxx family
AOZ06_RS45380	COG0596	Alpha beta hydrolase
AOZ06_RS45425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOZ06_RS45435	COG0154	amidase activity
AOZ06_RS45440	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOZ06_RS45465	COG0463	Glycosyl transferase, family 2
AOZ06_RS45495	COG1024	Enoyl-CoA hydratase
AOZ06_RS45500	COG1309	transcriptional regulator
AOZ06_RS45505	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS45520	COG0477	Major facilitator Superfamily
AOZ06_RS45545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOZ06_RS45550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOZ06_RS45555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOZ06_RS45605	COG0395	ABC-type sugar transport system, permease component
AOZ06_RS45610	COG1175	transmembrane transport
AOZ06_RS45620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS45625	COG1349	DNA-binding transcription factor activity
AOZ06_RS45630	COG1486	melibiose metabolic process
AOZ06_RS45650	COG1053	succinate dehydrogenase
AOZ06_RS45655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOZ06_RS45700	COG0154	amidase activity
AOZ06_RS45725	COG0604	alcohol dehydrogenase
AOZ06_RS45730	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS45735	COG0482	sulfurtransferase activity
AOZ06_RS45760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOZ06_RS45770	COG1307	EDD domain protein, DegV family
AOZ06_RS45780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS45795	COG0110	maltose O-acetyltransferase activity
AOZ06_RS45825	COG2226	methyltransferase
AOZ06_RS45835	COG1119	ATPase activity
AOZ06_RS45865	COG0058	SHG alpha-glucan phosphorylase activity
AOZ06_RS45885	COG0366	Alpha amylase catalytic
AOZ06_RS45900	COG0366	Alpha amylase catalytic
AOZ06_RS45910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOZ06_RS45920	COG2321	neutral zinc metallopeptidase
AOZ06_RS45930	COG2318	DinB family
AOZ06_RS45935	COG1846	Transcriptional regulator
AOZ06_RS45960	COG1950	PFAM Membrane protein of
AOZ06_RS45970	COG0842	Transport permease protein
AOZ06_RS45975	COG1131	(ABC) transporter
AOZ06_RS45980	COG3537	Alpha-1,2-mannosidase
AOZ06_RS45985	COG1609	Transcriptional regulator
AOZ06_RS46000	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS46075	COG2197	response regulator
AOZ06_RS46080	COG4585	Histidine kinase
AOZ06_RS46085	COG1136	(ABC) transporter
AOZ06_RS46100	COG0183	Belongs to the thiolase family
AOZ06_RS46105	COG0346	lactoylglutathione lyase activity
AOZ06_RS46130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS46140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOZ06_RS46175	COG2376	Dihydroxyacetone kinase
AOZ06_RS46180	COG1461	Dihydroxyacetone kinase
AOZ06_RS46185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOZ06_RS46195	COG3409	Peptidoglycan-binding domain 1 protein
AOZ06_RS46195	COG3757	hydrolase, family 25
AOZ06_RS46200	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AOZ06_RS46215	COG1024	Enoyl-CoA hydratase
AOZ06_RS46225	COG1126	abc transporter atp-binding protein
AOZ06_RS46230	COG0765	amino acid transport
AOZ06_RS46235	COG0765	amino acid transport
AOZ06_RS46245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOZ06_RS46245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AOZ06_RS46260	COG2186	Transcriptional regulator
AOZ06_RS46285	COG1595	DNA-templated transcription, initiation
AOZ06_RS46300	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOZ06_RS46325	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AOZ06_RS46340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOZ06_RS46375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOZ06_RS46380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AOZ06_RS46385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AOZ06_RS46390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOZ06_RS46395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOZ06_RS46400	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOZ06_RS46405	COG0356	it plays a direct role in the translocation of protons across the membrane
AOZ06_RS46415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOZ06_RS46420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOZ06_RS46430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS46435	COG3629	intracellular signal transduction
AOZ06_RS46435	COG3903	Transcriptional regulator
AOZ06_RS46450	COG1129	ABC transporter
AOZ06_RS46455	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS46460	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS46465	COG3903	Transcriptional regulator
AOZ06_RS46465	COG3629	intracellular signal transduction
AOZ06_RS46470	COG2890	protein-(glutamine-N5) methyltransferase activity
AOZ06_RS46475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AOZ06_RS46480	COG0254	rRNA binding
AOZ06_RS46490	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOZ06_RS46495	COG0083	homoserine kinase activity
AOZ06_RS46500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOZ06_RS46505	COG0460	homoserine dehydrogenase
AOZ06_RS46510	COG0019	diaminopimelate decarboxylase activity
AOZ06_RS46515	COG0018	arginyl-trna synthetase
AOZ06_RS46535	COG1940	carbohydrate kinase activity
AOZ06_RS46555	COG2124	cytochrome p450
AOZ06_RS46560	COG0076	glutamate decarboxylase activity
AOZ06_RS46570	COG0494	nUDIX hydrolase
AOZ06_RS46590	COG1982	Orn Lys Arg decarboxylase major
AOZ06_RS46605	COG0640	Transcriptional regulator
AOZ06_RS46640	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOZ06_RS46650	COG0529	Catalyzes the synthesis of activated sulfate
AOZ06_RS46705	COG3848	Pyruvate phosphate dikinase
AOZ06_RS46705	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS46710	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS46710	COG3848	Pyruvate phosphate dikinase
AOZ06_RS46715	COG3848	Pyruvate phosphate dikinase
AOZ06_RS46715	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS46720	COG3848	Pyruvate phosphate dikinase
AOZ06_RS46720	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS46765	COG4585	Histidine kinase
AOZ06_RS46770	COG2197	response regulator
AOZ06_RS46775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOZ06_RS46790	COG1649	PFAM Uncharacterised BCR, COG1649
AOZ06_RS46820	COG2197	response regulator
AOZ06_RS46825	COG4585	Histidine kinase
AOZ06_RS46835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOZ06_RS46845	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOZ06_RS46860	COG1929	Belongs to the glycerate kinase type-1 family
AOZ06_RS46865	COG2084	Dehydrogenase
AOZ06_RS46870	COG0277	FAD linked oxidase domain protein
AOZ06_RS46870	COG0247	lactate metabolic process
AOZ06_RS46875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOZ06_RS46895	COG2814	Major facilitator Superfamily
AOZ06_RS46915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS46920	COG2319	Wd-40 repeat
AOZ06_RS46920	COG5635	Nacht domain
AOZ06_RS46950	COG0574	Belongs to the PEP-utilizing enzyme family
AOZ06_RS46950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOZ06_RS46960	COG2197	response regulator
AOZ06_RS46970	COG2226	methyltransferase
AOZ06_RS46975	COG2124	cytochrome p450
AOZ06_RS46980	COG3864	Putative metallopeptidase domain
AOZ06_RS47010	COG0577	efflux transmembrane transporter activity
AOZ06_RS47015	COG1136	(ABC) transporter
AOZ06_RS47015	COG0577	efflux transmembrane transporter activity
AOZ06_RS47030	COG2226	methyltransferase
AOZ06_RS47035	COG4585	Histidine kinase
AOZ06_RS47050	COG2197	response regulator
AOZ06_RS47055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ06_RS47060	COG1073	alpha beta
AOZ06_RS47065	COG2226	methyltransferase
AOZ06_RS47135	COG1733	regulation of RNA biosynthetic process
AOZ06_RS47140	COG3629	intracellular signal transduction
AOZ06_RS47140	COG3903	Transcriptional regulator
AOZ06_RS47145	COG1278	Cold shock
AOZ06_RS47175	COG0210	DNA helicase
AOZ06_RS47250	COG4941	Belongs to the sigma-70 factor family
AOZ06_RS47270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOZ06_RS47280	COG4585	Histidine kinase
AOZ06_RS47285	COG2197	response regulator
AOZ06_RS47295	COG0747	negative chemotaxis
AOZ06_RS47300	COG0601	transmembrane transport
AOZ06_RS47305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOZ06_RS47310	COG2197	response regulator
AOZ06_RS47325	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOZ06_RS47325	COG1672	PFAM Archaeal ATPase
AOZ06_RS47330	COG1404	Belongs to the peptidase S8 family
AOZ06_RS47335	COG1404	Belongs to the peptidase S8 family
AOZ06_RS47345	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS47355	COG1802	Transcriptional regulator
AOZ06_RS47365	COG0515	serine threonine protein kinase
AOZ06_RS47365	COG2815	serine threonine protein kinase
AOZ06_RS47410	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AOZ06_RS47415	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AOZ06_RS47425	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AOZ06_RS47450	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AOZ06_RS47505	COG3250	beta-galactosidase activity
AOZ06_RS47515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS47520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOZ06_RS47550	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS47560	COG1053	succinate dehydrogenase
AOZ06_RS47565	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOZ06_RS47570	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS47585	COG0596	Alpha beta hydrolase
AOZ06_RS47595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOZ06_RS47600	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS47610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOZ06_RS47640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOZ06_RS47665	COG0346	lactoylglutathione lyase activity
AOZ06_RS47670	COG1695	Transcriptional regulator
AOZ06_RS47680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AOZ06_RS47680	COG2508	Transcriptional regulator
AOZ06_RS47685	COG0686	Belongs to the AlaDH PNT family
AOZ06_RS47705	COG1132	(ABC) transporter
AOZ06_RS47725	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ06_RS47725	COG0567	Dehydrogenase, E1 component
AOZ06_RS47765	COG1228	amidohydrolase
AOZ06_RS47780	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AOZ06_RS47785	COG2986	histidine ammonia-lyase
AOZ06_RS47805	COG1174	glycine betaine transport
AOZ06_RS47810	COG1174	glycine betaine transport
AOZ06_RS47815	COG0517	IMP dehydrogenase activity
AOZ06_RS47815	COG1125	glycine betaine transport
AOZ06_RS47830	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AOZ06_RS47895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOZ06_RS47930	COG1597	lipid kinase activity
AOZ06_RS47945	COG5662	AntiSigma factor
AOZ06_RS47950	COG1595	DNA-templated transcription, initiation
AOZ06_RS47965	COG2135	peptidase activity
AOZ06_RS47970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOZ06_RS47975	COG1162	GTPase activity
AOZ06_RS47985	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS48000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ06_RS48010	COG0653	protein targeting
AOZ06_RS48015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOZ06_RS48025	COG5401	PFAM Sporulation and spore germination
AOZ06_RS48030	COG5000	phosphorelay sensor kinase activity
AOZ06_RS48030	COG5002	protein histidine kinase activity
AOZ06_RS48035	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS48055	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOZ06_RS48075	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOZ06_RS48085	COG0531	amino acid
AOZ06_RS48095	COG1482	cell wall glycoprotein biosynthetic process
AOZ06_RS48105	COG2835	tetraacyldisaccharide 4'-kinase activity
AOZ06_RS48110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOZ06_RS48135	COG1994	Peptidase M50
AOZ06_RS48145	COG4221	oxidoreductase activity
AOZ06_RS48150	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOZ06_RS48155	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AOZ06_RS48155	COG0778	Nitroreductase
AOZ06_RS48190	COG0297	glycogen (starch) synthase activity
AOZ06_RS48230	COG1316	TRANSCRIPTIONal
AOZ06_RS48235	COG1316	TRANSCRIPTIONal
AOZ06_RS48250	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS48270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOZ06_RS48310	COG2205	protein histidine kinase activity
AOZ06_RS48320	COG0483	inositol monophosphate 1-phosphatase activity
AOZ06_RS48350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOZ06_RS48365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOZ06_RS48375	COG2936	dipeptidyl-peptidase activity
AOZ06_RS48405	COG0424	maF-like protein
AOZ06_RS48410	COG1301	dicarboxylic acid transport
AOZ06_RS48420	COG4770	biotin carboxylase activity
AOZ06_RS48435	COG1136	(ABC) transporter
AOZ06_RS48435	COG0577	efflux transmembrane transporter activity
AOZ06_RS48440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOZ06_RS48470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOZ06_RS48475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOZ06_RS48480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOZ06_RS48515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS48540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOZ06_RS48540	COG1473	amidohydrolase
AOZ06_RS48565	COG2815	serine threonine protein kinase
AOZ06_RS48565	COG0515	serine threonine protein kinase
AOZ06_RS48590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOZ06_RS48605	COG1404	Belongs to the peptidase S8 family
AOZ06_RS48615	COG0667	Aldo Keto reductase
AOZ06_RS48625	COG3654	unkown
AOZ06_RS48640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOZ06_RS48650	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOZ06_RS48655	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS48660	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS48680	COG0791	NLP P60 protein
AOZ06_RS48680	COG3883	PFAM NLP P60 protein
AOZ06_RS48695	COG1522	sequence-specific DNA binding
AOZ06_RS48700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOZ06_RS48720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOZ06_RS48745	COG0671	phosphoesterase, PA-phosphatase related
AOZ06_RS48765	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOZ06_RS48775	COG3845	ABC transporter
AOZ06_RS48780	COG1744	ABC transporter substrate-binding protein PnrA-like
AOZ06_RS48810	COG2009	succinate dehydrogenase
AOZ06_RS48825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOZ06_RS48855	COG1686	Belongs to the peptidase S11 family
AOZ06_RS48860	COG1686	Belongs to the peptidase S11 family
AOZ06_RS48865	COG1295	ribonuclease BN
AOZ06_RS48870	COG0180	Tryptophanyl-tRNA synthetase
AOZ06_RS48880	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOZ06_RS48885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOZ06_RS48925	COG2814	Major facilitator Superfamily
AOZ06_RS48935	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS48940	COG5002	protein histidine kinase activity
AOZ06_RS48955	COG0039	L-malate dehydrogenase activity
AOZ06_RS48970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOZ06_RS49000	COG0587	DNA-directed DNA polymerase activity
AOZ06_RS49015	COG4946	Tricorn protease homolog
AOZ06_RS49015	COG1506	peptidase
AOZ06_RS49015	COG0823	Involved in the tonB-independent uptake of proteins
AOZ06_RS49020	COG0789	Transcriptional regulator
AOZ06_RS49025	COG1522	sequence-specific DNA binding
AOZ06_RS49030	COG0667	Aldo Keto reductase
AOZ06_RS49070	COG2814	Major facilitator Superfamily
AOZ06_RS49110	COG0045	succinate-CoA ligase (ADP-forming) activity
AOZ06_RS49140	COG0586	Pfam SNARE associated Golgi protein
AOZ06_RS49165	COG0515	serine threonine protein kinase
AOZ06_RS49175	COG0583	DNA-binding transcription factor activity
AOZ06_RS49180	COG0697	spore germination
AOZ06_RS49210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOZ06_RS49210	COG0519	Catalyzes the synthesis of GMP from XMP
AOZ06_RS49215	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS49230	COG0277	FAD linked oxidase domain protein
AOZ06_RS49255	COG0516	GMP reductase activity
AOZ06_RS49310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOZ06_RS49315	COG0459	protein refolding
AOZ06_RS49340	COG4977	sequence-specific DNA binding
AOZ06_RS49345	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS49355	COG0583	DNA-binding transcription factor activity
AOZ06_RS49375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOZ06_RS49395	COG0477	Major facilitator Superfamily
AOZ06_RS49400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AOZ06_RS49400	COG0825	malonyl-CoA metabolic process
AOZ06_RS49405	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS49415	COG1309	transcriptional regulator
AOZ06_RS49420	COG3118	belongs to the thioredoxin family
AOZ06_RS49430	COG0456	acetyltransferase
AOZ06_RS49430	COG1214	PFAM Peptidase M22, glycoprotease
AOZ06_RS49435	COG0456	acetyltransferase
AOZ06_RS49440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AOZ06_RS49450	COG3540	Alkaline phosphatase
AOZ06_RS49495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOZ06_RS49500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOZ06_RS49505	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AOZ06_RS49540	COG2197	response regulator
AOZ06_RS49545	COG4585	Histidine kinase
AOZ06_RS49555	COG1404	Belongs to the peptidase S8 family
AOZ06_RS49565	COG1674	ftsk spoiiie
AOZ06_RS49600	COG0203	ribosomal protein L17
AOZ06_RS49605	COG0202	RNA polymerase activity
AOZ06_RS49610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOZ06_RS49615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOZ06_RS49620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOZ06_RS49625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOZ06_RS49630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOZ06_RS49660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AOZ06_RS49690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AOZ06_RS49695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOZ06_RS49700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AOZ06_RS49705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOZ06_RS49715	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOZ06_RS49720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AOZ06_RS49725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AOZ06_RS49730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOZ06_RS49735	COG0255	Belongs to the universal ribosomal protein uL29 family
AOZ06_RS49745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOZ06_RS49750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AOZ06_RS49755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOZ06_RS49760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOZ06_RS49765	COG0089	rRNA binding
AOZ06_RS49770	COG0088	Forms part of the polypeptide exit tunnel
AOZ06_RS49775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOZ06_RS49780	COG0051	transcription antitermination factor activity, RNA binding
AOZ06_RS49785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOZ06_RS49790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOZ06_RS49795	COG0049	tRNA binding
AOZ06_RS49800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOZ06_RS49840	COG2197	response regulator
AOZ06_RS49845	COG4585	Histidine kinase
AOZ06_RS49875	COG2272	Belongs to the type-B carboxylesterase lipase family
AOZ06_RS49880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOZ06_RS49885	COG0085	RNA polymerase activity
AOZ06_RS49920	COG3903	Transcriptional regulator
AOZ06_RS49920	COG3629	intracellular signal transduction
AOZ06_RS49965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOZ06_RS50015	COG0222	ribosome binding
AOZ06_RS50040	COG0081	regulation of translation
AOZ06_RS50045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOZ06_RS50065	COG0436	Aminotransferase
AOZ06_RS50075	COG2030	dehydratase
AOZ06_RS50110	COG0501	Belongs to the peptidase M48B family
AOZ06_RS50115	COG1595	DNA-templated transcription, initiation
AOZ06_RS50125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AOZ06_RS50130	COG1666	GTP binding
AOZ06_RS50140	COG1819	glycosyl
AOZ06_RS50145	COG3973	AAA domain
AOZ06_RS50160	COG1834	amidinotransferase
AOZ06_RS50165	COG1522	sequence-specific DNA binding
AOZ06_RS50175	COG0674	pyruvate-flavodoxin oxidoreductase activity
AOZ06_RS50175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AOZ06_RS50180	COG1013	pyruvate-flavodoxin oxidoreductase activity
AOZ06_RS50195	COG3706	GGDEF domain
AOZ06_RS50205	COG0142	geranyltranstransferase activity
AOZ06_RS50210	COG1007	ATP synthesis coupled electron transport
AOZ06_RS50225	COG0713	ATP synthesis coupled electron transport
AOZ06_RS50230	COG0839	Belongs to the complex I subunit 6 family
AOZ06_RS50235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS50240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AOZ06_RS50245	COG1034	ATP synthesis coupled electron transport
AOZ06_RS50260	COG0649	NAD binding
AOZ06_RS50265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS50270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOZ06_RS50280	COG0644	oxidoreductase
AOZ06_RS50290	COG2226	methyltransferase
AOZ06_RS50295	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS50330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOZ06_RS50385	COG1522	sequence-specific DNA binding
AOZ06_RS50405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOZ06_RS50415	COG0785	Cytochrome C biogenesis protein
AOZ06_RS50420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOZ06_RS50425	COG0406	alpha-ribazole phosphatase activity
AOZ06_RS50430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOZ06_RS50440	COG1136	(ABC) transporter
AOZ06_RS50440	COG0577	efflux transmembrane transporter activity
AOZ06_RS50445	COG1136	(ABC) transporter
AOZ06_RS50475	COG0113	porphobilinogen synthase activity
AOZ06_RS50485	COG0181	hydroxymethylbilane synthase activity
AOZ06_RS50490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOZ06_RS50495	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AOZ06_RS50510	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS50545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOZ06_RS50555	COG0506	proline dehydrogenase activity
AOZ06_RS50580	COG5002	protein histidine kinase activity
AOZ06_RS50595	COG0588	phosphoglycerate mutase activity
AOZ06_RS50610	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS50615	COG2267	carboxylic ester hydrolase activity
AOZ06_RS50625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOZ06_RS50660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOZ06_RS50700	COG2130	NADP-dependent
AOZ06_RS50715	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS50725	COG2197	response regulator
AOZ06_RS50740	COG0110	maltose O-acetyltransferase activity
AOZ06_RS50755	COG2733	membrane
AOZ06_RS50805	COG3469	chitinase activity
AOZ06_RS50825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOZ06_RS50865	COG2244	polysaccharide biosynthetic process
AOZ06_RS50870	COG0596	Alpha beta hydrolase
AOZ06_RS50895	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS50910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOZ06_RS50925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOZ06_RS50935	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS50965	COG0438	transferase activity, transferring glycosyl groups
AOZ06_RS51000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOZ06_RS51010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOZ06_RS51045	COG1278	Cold shock
AOZ06_RS51050	COG1376	ErfK ybiS ycfS ynhG family protein
AOZ06_RS51055	COG2409	Drug exporters of the RND superfamily
AOZ06_RS51060	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS51065	COG2205	protein histidine kinase activity
AOZ06_RS51080	COG0515	serine threonine protein kinase
AOZ06_RS51085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS51120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOZ06_RS51155	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS51170	COG2197	response regulator
AOZ06_RS51175	COG4585	Histidine kinase
AOZ06_RS51210	COG3629	intracellular signal transduction
AOZ06_RS51210	COG3903	Transcriptional regulator
AOZ06_RS51215	COG1957	nucleoside hydrolase
AOZ06_RS51255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOZ06_RS51265	COG2378	regulation of single-species biofilm formation
AOZ06_RS51280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AOZ06_RS51290	COG1733	regulation of RNA biosynthetic process
AOZ06_RS51385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOZ06_RS51410	COG0745	RESPONSE REGULATOR receiver
AOZ06_RS51445	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AOZ06_RS51455	COG1984	allophanate hydrolase subunit 2
AOZ06_RS51485	COG3246	L-lysine catabolic process to acetate
AOZ06_RS51505	COG3962	Belongs to the TPP enzyme family
AOZ06_RS51510	COG3718	enzyme involved in inositol metabolism
AOZ06_RS51520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS51540	COG1082	Xylose isomerase domain protein TIM barrel
AOZ06_RS51575	COG4257	antibiotic catabolic process
AOZ06_RS51600	COG3290	protein histidine kinase activity
AOZ06_RS51605	COG4565	transcriptional regulatory protein
AOZ06_RS51620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOZ06_RS51670	COG0583	DNA-binding transcription factor activity
AOZ06_RS51675	COG0667	Aldo Keto reductase
AOZ06_RS51695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOZ06_RS51700	COG0047	phosphoribosylformylglycinamidine synthase activity
AOZ06_RS51705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOZ06_RS51710	COG1012	belongs to the aldehyde dehydrogenase family
AOZ06_RS51725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOZ06_RS51735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AOZ06_RS51745	COG1132	(ABC) transporter
AOZ06_RS51770	COG0633	Ferredoxin
AOZ06_RS51770	COG3217	Mosc domain protein beta barrel domain protein
AOZ06_RS51775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOZ06_RS51800	COG1595	DNA-templated transcription, initiation
AOZ06_RS51815	COG0436	Aminotransferase
AOZ06_RS51825	COG5280	Phage tail tape measure protein TP901
AOZ06_RS51825	COG3953	SLT domain
AOZ06_RS51855	COG0151	Belongs to the GarS family
AOZ06_RS51870	COG0584	glycerophosphoryl diester phosphodiesterase
AOZ06_RS51885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOZ06_RS51890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOZ06_RS51895	COG1116	anion transmembrane transporter activity
AOZ06_RS51900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOZ06_RS51905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOZ06_RS51915	COG3321	synthase
AOZ06_RS51915	COG0604	alcohol dehydrogenase
AOZ06_RS51945	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOZ06_RS51960	COG0300	oxidoreductase activity
AOZ06_RS51995	COG0277	FAD linked oxidase domain protein
AOZ06_RS52000	COG0657	acetylesterase activity
AOZ06_RS52015	COG0586	Pfam SNARE associated Golgi protein
AOZ06_RS52020	COG0346	lactoylglutathione lyase activity
AOZ06_RS52030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS52050	COG1609	Transcriptional regulator
AOZ06_RS52055	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS52065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOZ06_RS52085	COG0300	oxidoreductase activity
AOZ06_RS52095	COG0542	response to heat
AOZ06_RS52120	COG0789	Transcriptional regulator
AOZ06_RS52125	COG0484	heat shock protein binding
AOZ06_RS52130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOZ06_RS52135	COG0443	Heat shock 70 kDa protein
AOZ06_RS52170	COG0247	lactate metabolic process
AOZ06_RS52170	COG2181	nitrate reductase activity
AOZ06_RS52185	COG2267	carboxylic ester hydrolase activity
AOZ06_RS52190	COG1802	Transcriptional regulator
AOZ06_RS52215	COG0318	PFAM AMP-dependent synthetase and ligase
AOZ06_RS52220	COG1028	Short-chain dehydrogenase reductase Sdr
AOZ06_RS52250	COG0546	phosphoglycolate phosphatase activity
AOZ06_RS52310	COG2197	response regulator
AOZ06_RS52315	COG1960	acyl-CoA dehydrogenase activity
AOZ06_RS52325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOZ06_RS52360	COG1126	abc transporter atp-binding protein
AOZ06_RS52365	COG0765	amino acid transport
AOZ06_RS52370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOZ06_RS52385	COG1515	deoxyribonuclease V activity
AOZ06_RS52400	COG0022	dehydrogenase e1 component
AOZ06_RS52405	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOZ06_RS52420	COG0667	Aldo Keto reductase
AOZ06_RS52425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS52440	COG1309	transcriptional regulator
AOZ06_RS52455	COG0183	Belongs to the thiolase family
AOZ06_RS52465	COG1940	carbohydrate kinase activity
AOZ06_RS52470	COG0456	acetyltransferase
AOZ06_RS52470	COG1846	Transcriptional regulator
AOZ06_RS52500	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AOZ06_RS52505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOZ06_RS52510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOZ06_RS52525	COG4585	Histidine kinase
AOZ06_RS52530	COG2197	response regulator
AOZ06_RS52550	COG1131	(ABC) transporter
AOZ06_RS52565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOZ06_RS52570	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOZ06_RS52575	COG0402	S-adenosylhomocysteine deaminase activity
AOZ06_RS52590	COG0758	DNA mediated transformation
AOZ06_RS52590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOZ06_RS52625	COG1260	myo-inositol-1-phosphate synthase
AOZ06_RS52630	COG1695	Transcriptional regulator
AOZ06_RS52640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOZ06_RS52670	COG0360	Binds together with S18 to 16S ribosomal RNA
AOZ06_RS52675	COG0629	single-stranded DNA binding
AOZ06_RS52680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOZ06_RS52685	COG0359	binds to the 23S rRNA
AOZ06_RS52710	COG0477	Major facilitator Superfamily
AOZ06_RS52715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOZ06_RS52735	COG3384	dioxygenase
AOZ06_RS52775	COG2197	response regulator
AOZ06_RS52785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOZ06_RS52790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOZ06_RS52810	COG0495	leucyl-tRNA aminoacylation
AOZ06_RS52825	COG1678	Uncharacterized ACR, COG1678
AOZ06_RS52835	COG0617	tRNA 3'-terminal CCA addition
AOZ06_RS52860	COG1595	DNA-templated transcription, initiation
AOZ06_RS52875	COG3118	belongs to the thioredoxin family
AOZ06_RS52875	COG0492	ferredoxin-NADP+ reductase activity
AOZ06_RS52880	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOZ06_RS52880	COG3409	Peptidoglycan-binding domain 1 protein
AOZ06_RS52890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOZ06_RS52905	COG1192	Involved in chromosome partitioning
AOZ06_RS52910	COG0357	Ribosomal RNA small subunit methyltransferase G
AOZ06_RS52920	COG0706	membrane insertase activity
AOZ06_RS52925	COG0594	ribonuclease P activity