locus-tag	class	description
AM345_RS00010	COG1566	PFAM secretion protein HlyD family protein
AM345_RS00030	COG3722	fumarate hydratase activity
AM345_RS00050	COG2186	Transcriptional regulator
AM345_RS00060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM345_RS00085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM345_RS00090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM345_RS00100	COG4942	peptidase
AM345_RS00105	COG2861	carbohydrate metabolic process
AM345_RS00110	COG0463	Glycosyl transferase, family 2
AM345_RS00125	COG0156	8-amino-7-oxononanoate synthase activity
AM345_RS00140	COG0859	PFAM glycosyl transferase family 9
AM345_RS00145	COG0859	PFAM glycosyl transferase family 9
AM345_RS00150	COG0438	transferase activity, transferring glycosyl groups
AM345_RS00165	COG1216	Glycosyl transferase, family 2
AM345_RS00180	COG1519	Transferase
AM345_RS00205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM345_RS00215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM345_RS00240	COG1561	YicC-like family, N-terminal region
AM345_RS00245	COG2860	membrane
AM345_RS00250	COG2194	sulfuric ester hydrolase activity
AM345_RS00260	COG0194	GDP metabolic process
AM345_RS00270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM345_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM345_RS00280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM345_RS00285	COG1494	fructose-1,6-bisphosphatase
AM345_RS00295	COG3152	Membrane
AM345_RS00320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM345_RS00325	COG3074	FtsZ-dependent cytokinesis
AM345_RS00340	COG0786	glutamate:sodium symporter activity
AM345_RS00345	COG2233	PERMEase
AM345_RS00350	COG2982	Protein involved in outer membrane biogenesis
AM345_RS00355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS00355	COG1263	PTS System
AM345_RS00360	COG1486	melibiose metabolic process
AM345_RS00380	COG1940	carbohydrate kinase activity
AM345_RS00385	COG0191	fructose-bisphosphate aldolase activity
AM345_RS00395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS00395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS00400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS00405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS00405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS00405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS00410	COG3711	transcriptional antiterminator
AM345_RS00415	COG1501	Belongs to the glycosyl hydrolase 31 family
AM345_RS00420	COG2211	Major facilitator Superfamily
AM345_RS00465	COG1064	alcohol dehydrogenase
AM345_RS00475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM345_RS00485	COG1464	Belongs to the NlpA lipoprotein family
AM345_RS00490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS00490	COG1263	PTS System
AM345_RS00505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM345_RS00555	COG0697	spore germination
AM345_RS00565	COG1609	Transcriptional regulator
AM345_RS00575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM345_RS00575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM345_RS00580	COG4580	involved in the transport of maltose and maltodextrins
AM345_RS00610	COG2188	Transcriptional regulator
AM345_RS00645	COG2271	Major facilitator Superfamily
AM345_RS00655	COG2197	response regulator
AM345_RS00660	COG0440	acetolactate synthase activity
AM345_RS00665	COG0028	Belongs to the TPP enzyme family
AM345_RS00690	COG2814	Major facilitator Superfamily
AM345_RS00695	COG0583	DNA-binding transcription factor activity
AM345_RS00700	COG2610	gluconate transmembrane transporter activity
AM345_RS00720	COG2149	membrane
AM345_RS00735	COG2188	Transcriptional regulator
AM345_RS00755	COG5645	(Lipo)protein
AM345_RS00760	COG0823	Involved in the tonB-independent uptake of proteins
AM345_RS00765	COG2271	Major facilitator Superfamily
AM345_RS00775	COG0800	Aldolase
AM345_RS00780	COG3734	2-keto-3-deoxy-galactonokinase
AM345_RS00785	COG2186	Transcriptional regulator
AM345_RS00800	COG0561	phosphatase activity
AM345_RS00805	COG0187	DNA topoisomerase II activity
AM345_RS00815	COG0592	DNA-directed DNA polymerase activity
AM345_RS00825	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM345_RS00835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM345_RS00870	COG2091	lysine biosynthetic process via aminoadipic acid
AM345_RS00875	COG0431	NADPH-dependent FMN reductase
AM345_RS00880	COG2252	PERMEase
AM345_RS00890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM345_RS00895	COG0363	glucosamine-6-phosphate deaminase activity
AM345_RS00900	COG2382	esterase
AM345_RS00915	COG0704	Plays a role in the regulation of phosphate uptake
AM345_RS00925	COG0581	inorganic phosphate transmembrane transporter activity
AM345_RS00930	COG0573	inorganic phosphate transmembrane transporter activity
AM345_RS00935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM345_RS00945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM345_RS00955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM345_RS00960	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM345_RS00995	COG3312	ion transport
AM345_RS01010	COG0716	FMN binding
AM345_RS01015	COG1522	sequence-specific DNA binding
AM345_RS01045	COG1129	ABC transporter
AM345_RS01050	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS01060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM345_RS01065	COG1609	Transcriptional regulator
AM345_RS01070	COG0477	Major facilitator Superfamily
AM345_RS01075	COG2186	Transcriptional regulator
AM345_RS01125	COG3085	chromosome segregation
AM345_RS01130	COG0606	chelatase, subunit chli
AM345_RS01145	COG3978	acetolactate synthase activity
AM345_RS01150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM345_RS01160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM345_RS01165	COG0583	DNA-binding transcription factor activity
AM345_RS01175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM345_RS01180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM345_RS01190	COG1811	Na channel or pump
AM345_RS01200	COG0583	DNA-binding transcription factor activity
AM345_RS01215	COG3118	belongs to the thioredoxin family
AM345_RS01225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM345_RS01230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM345_RS01240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM345_RS01245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM345_RS01250	COG1088	dTDP-glucose 4,6-dehydratase activity
AM345_RS01255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM345_RS01260	COG0456	acetyltransferase
AM345_RS01265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM345_RS01270	COG2244	polysaccharide biosynthetic process
AM345_RS01320	COG3071	HemY protein
AM345_RS01325	COG2959	enzyme of heme biosynthesis
AM345_RS01330	COG1587	Uroporphyrinogen-III synthase
AM345_RS01340	COG3072	Adenylate cyclase
AM345_RS01365	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM345_RS01370	COG1011	Hydrolase
AM345_RS01375	COG0210	DNA helicase
AM345_RS01390	COG2050	protein possibly involved in aromatic compounds catabolism
AM345_RS01405	COG1280	lysine exporter protein (LysE YggA)
AM345_RS01415	COG1280	lysine exporter protein (LysE YggA)
AM345_RS01420	COG2267	carboxylic ester hydrolase activity
AM345_RS01425	COG0561	phosphatase activity
AM345_RS01430	COG0697	spore germination
AM345_RS01435	COG0583	DNA-binding transcription factor activity
AM345_RS01465	COG3165	ubiquinone biosynthetic process from chorismate
AM345_RS01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM345_RS01485	COG0805	protein transport
AM345_RS01530	COG1739	Uncharacterized protein family UPF0029
AM345_RS01540	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM345_RS01570	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM345_RS01580	COG3084	Protein conserved in bacteria
AM345_RS01585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM345_RS01595	COG0204	Acyl-transferase
AM345_RS01630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM345_RS01640	COG3852	Histidine kinase
AM345_RS01660	COG1011	Hydrolase
AM345_RS01675	COG0456	acetyltransferase
AM345_RS01680	COG0657	acetylesterase activity
AM345_RS01690	COG2864	formate dehydrogenase
AM345_RS01695	COG0437	4 iron, 4 sulfur cluster binding
AM345_RS01720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM345_RS01730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM345_RS01735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM345_RS01740	COG2731	YhcH YjgK YiaL family protein
AM345_RS01745	COG2271	Major facilitator Superfamily
AM345_RS01755	COG1454	alcohol dehydrogenase
AM345_RS01795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM345_RS01800	COG2258	MOSC domain
AM345_RS01805	COG2205	protein histidine kinase activity
AM345_RS01810	COG0745	RESPONSE REGULATOR receiver
AM345_RS01815	COG3678	ATP-independent chaperone mediated protein folding
AM345_RS01820	COG4974	Belongs to the 'phage' integrase family
AM345_RS01880	COG4695	Portal protein
AM345_RS02035	COG1575	Belongs to the MenA family. Type 1 subfamily
AM345_RS02050	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM345_RS02055	COG1609	Transcriptional regulator
AM345_RS02060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM345_RS02075	COG0626	cystathionine gamma-synthase activity
AM345_RS02080	COG0460	homoserine dehydrogenase
AM345_RS02080	COG0527	aspartate kinase activity
AM345_RS02090	COG0697	spore germination
AM345_RS02095	COG0371	Dehydrogenase
AM345_RS02105	COG2207	Transcriptional regulator
AM345_RS02110	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM345_RS02125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM345_RS02150	COG0583	DNA-binding transcription factor activity
AM345_RS02260	COG0250	Participates in transcription elongation, termination and antitermination
AM345_RS02300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM345_RS02305	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM345_RS02315	COG3706	GGDEF domain
AM345_RS02335	COG2104	thiamine diphosphate biosynthetic process
AM345_RS02340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM345_RS02355	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM345_RS02395	COG4191	Histidine kinase
AM345_RS02405	COG0151	Belongs to the GarS family
AM345_RS02460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM345_RS02480	COG0646	methionine synthase
AM345_RS02480	COG1410	methionine synthase
AM345_RS02485	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM345_RS02500	COG1187	pseudouridine synthase activity
AM345_RS02515	COG4650	regulator
AM345_RS02530	COG1690	Belongs to the RtcB family
AM345_RS02535	COG3541	Predicted nucleotidyltransferase
AM345_RS02540	COG0527	aspartate kinase activity
AM345_RS02555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM345_RS02560	COG0251	oxidation-reduction process
AM345_RS02610	COG4580	involved in the transport of maltose and maltodextrins
AM345_RS02635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM345_RS02645	COG0534	Mate efflux family protein
AM345_RS02650	COG3237	CsbD-like
AM345_RS02655	COG0735	belongs to the Fur family
AM345_RS02665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM345_RS02680	COG0305	Participates in initiation and elongation during chromosome replication
AM345_RS02685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM345_RS02690	COG1448	Aminotransferase
AM345_RS02700	COG0432	Pfam Uncharacterised protein family UPF0047
AM345_RS02705	COG2315	Protein conserved in bacteria
AM345_RS02720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM345_RS02735	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM345_RS02750	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM345_RS02760	COG0789	Transcriptional regulator
AM345_RS02765	COG0625	glutathione transferase activity
AM345_RS02775	COG2252	PERMEase
AM345_RS02780	COG0025	NhaP-type Na H and K H
AM345_RS02785	COG0583	DNA-binding transcription factor activity
AM345_RS02795	COG1346	cytolysis
AM345_RS02800	COG3539	Fimbrial protein
AM345_RS02815	COG3539	Fimbrial protein
AM345_RS02820	COG3539	Fimbrial protein
AM345_RS02830	COG3162	membrane
AM345_RS02835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM345_RS02845	COG1301	dicarboxylic acid transport
AM345_RS02850	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM345_RS02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS02880	COG1129	ABC transporter
AM345_RS02885	COG0784	Response regulator, receiver
AM345_RS02885	COG4191	Histidine kinase
AM345_RS02895	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM345_RS02905	COG3454	Phosphonate metabolism
AM345_RS02910	COG4778	phosphonate C-P lyase system protein PhnL
AM345_RS02915	COG4107	phosphonate C-P lyase system protein PhnK
AM345_RS02920	COG3627	carbon phosphorus lyase activity
AM345_RS02925	COG3626	phosphonate metabolism
AM345_RS02930	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM345_RS02935	COG3624	Phosphonate C-P lyase system protein PhnG
AM345_RS02940	COG2188	Transcriptional regulator
AM345_RS02945	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM345_RS02950	COG2824	Alkylphosphonate utilization operon protein PhnA
AM345_RS02965	COG2169	Transcriptional regulator
AM345_RS02975	COG1486	melibiose metabolic process
AM345_RS03010	COG0861	Integral membrane protein TerC family
AM345_RS03025	COG1215	transferase activity, transferring glycosyl groups
AM345_RS03030	COG0726	polysaccharide deacetylase
AM345_RS03030	COG1649	PFAM Uncharacterised BCR, COG1649
AM345_RS03035	COG0457	Tetratricopeptide repeat
AM345_RS03075	COG1309	transcriptional regulator
AM345_RS03090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM345_RS03095	COG1027	Aspartate ammonia-lyase
AM345_RS03105	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM345_RS03110	COG0531	amino acid
AM345_RS03120	COG0459	protein refolding
AM345_RS03175	COG1509	lysine 2,3-aminomutase activity
AM345_RS03190	COG5510	response to toxic substance
AM345_RS03195	COG2076	Multidrug Resistance protein
AM345_RS03215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM345_RS03220	COG1053	succinate dehydrogenase
AM345_RS03235	COG1511	domain protein
AM345_RS03235	COG3264	Mechanosensitive ion channel
AM345_RS03255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM345_RS03260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS03280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM345_RS03285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM345_RS03285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM345_RS03290	COG0802	atpase or kinase
AM345_RS03295	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM345_RS03315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM345_RS03320	COG0330	HflC and HflK could
AM345_RS03325	COG0330	HflC and HflK could
AM345_RS03335	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM345_RS03350	COG0557	exoribonuclease II activity
AM345_RS03355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM345_RS03360	COG0477	Major facilitator Superfamily
AM345_RS03365	COG1960	acyl-CoA dehydrogenase activity
AM345_RS03375	COG3650	response to hydrogen peroxide
AM345_RS03380	COG1073	alpha beta
AM345_RS03440	COG2965	DNA replication, synthesis of RNA primer
AM345_RS03445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM345_RS03450	COG0359	binds to the 23S rRNA
AM345_RS03460	COG3061	Opacity-associated protein A
AM345_RS03465	COG0545	Peptidyl-prolyl cis-trans isomerase
AM345_RS03470	COG1113	amino acid transport
AM345_RS03480	COG0697	spore germination
AM345_RS03490	COG0702	epimerase
AM345_RS03495	COG1733	regulation of RNA biosynthetic process
AM345_RS03510	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM345_RS03520	COG1253	flavin adenine dinucleotide binding
AM345_RS03530	COG0729	surface antigen
AM345_RS03535	COG2911	Protein conserved in bacteria
AM345_RS03540	COG2105	PFAM AIG2 family protein
AM345_RS03550	COG1879	ABC-type sugar transport system periplasmic component
AM345_RS03555	COG1129	ABC transporter
AM345_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS03575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM345_RS03590	COG0312	modulator of DNA gyrase
AM345_RS03625	COG3964	amidohydrolase
AM345_RS03640	COG2706	6-phosphogluconolactonase activity
AM345_RS03645	COG3711	transcriptional antiterminator
AM345_RS03645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS03650	COG0602	queuosine metabolic process
AM345_RS03675	COG1486	melibiose metabolic process
AM345_RS03680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM345_RS03685	COG0366	Alpha amylase catalytic
AM345_RS03690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS03690	COG1263	PTS System
AM345_RS03695	COG1609	Transcriptional regulator
AM345_RS03710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM345_RS03715	COG0251	oxidation-reduction process
AM345_RS03735	COG2731	YhcH YjgK YiaL family protein
AM345_RS03740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM345_RS03760	COG0525	valine-tRNA ligase activity
AM345_RS03765	COG2927	DNA polymerase III (CHI subunit)
AM345_RS03780	COG0795	lipopolysaccharide-transporting ATPase activity
AM345_RS03785	COG0795	lipopolysaccharide-transporting ATPase activity
AM345_RS03795	COG0433	COG0433 Predicted ATPase
AM345_RS03810	COG3718	enzyme involved in inositol metabolism
AM345_RS03815	COG0837	glucose binding
AM345_RS03815	COG1737	Transcriptional regulator
AM345_RS03820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM345_RS03825	COG3962	Belongs to the TPP enzyme family
AM345_RS03835	COG1082	Xylose isomerase domain protein TIM barrel
AM345_RS03845	COG2814	Major facilitator Superfamily
AM345_RS03855	COG3842	ATPase activity
AM345_RS03860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM345_RS03865	COG0395	ABC-type sugar transport system, permease component
AM345_RS03870	COG1175	transmembrane transport
AM345_RS03875	COG1064	alcohol dehydrogenase
AM345_RS03880	COG0659	secondary active sulfate transmembrane transporter activity
AM345_RS03885	COG0288	reversible hydration of carbon dioxide
AM345_RS03900	COG1401	restriction endodeoxyribonuclease activity
AM345_RS03915	COG1196	nuclear chromosome segregation
AM345_RS03940	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AM345_RS03980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM345_RS03985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS03990	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS03995	COG1538	Outer membrane efflux protein
AM345_RS04005	COG0745	RESPONSE REGULATOR receiver
AM345_RS04010	COG5002	protein histidine kinase activity
AM345_RS04015	COG2850	peptidyl-arginine hydroxylation
AM345_RS04045	COG0842	Transport permease protein
AM345_RS04050	COG1129	ABC transporter
AM345_RS04050	COG0842	Transport permease protein
AM345_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS04065	COG3706	GGDEF domain
AM345_RS04090	COG4869	propanediol catabolic process
AM345_RS04100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM345_RS04105	COG1882	Formate acetyltransferase
AM345_RS04120	COG1454	alcohol dehydrogenase
AM345_RS04120	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS04165	COG3716	PTS system mannose fructose sorbose family IID component
AM345_RS04170	COG3715	PTS system
AM345_RS04175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS04175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS04195	COG0531	amino acid
AM345_RS04205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM345_RS04210	COG5457	Domain of unknown function (DUF1127)
AM345_RS04220	COG1566	PFAM secretion protein HlyD family protein
AM345_RS04235	COG3366	ferrous iron transmembrane transporter activity
AM345_RS04240	COG0700	Nucleoside recognition
AM345_RS04245	COG1473	amidohydrolase
AM345_RS04255	COG1924	4 iron, 4 sulfur cluster binding
AM345_RS04260	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM345_RS04270	COG2814	Major facilitator Superfamily
AM345_RS04275	COG2733	membrane
AM345_RS04285	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS04290	COG0523	cobalamin synthesis protein
AM345_RS04295	COG2879	small protein
AM345_RS04300	COG1966	Carbon starvation protein
AM345_RS04305	COG2831	hemolysin activation secretion protein
AM345_RS04310	COG3210	domain, Protein
AM345_RS04340	COG3210	domain, Protein
AM345_RS04345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM345_RS04350	COG2368	4-hydroxyphenylacetate
AM345_RS04370	COG3971	2-oxopent-4-enoate hydratase activity
AM345_RS04380	COG3384	dioxygenase
AM345_RS04385	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS04395	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM345_RS04405	COG1846	Transcriptional regulator
AM345_RS04410	COG2271	Major facilitator Superfamily
AM345_RS04415	COG1802	Transcriptional regulator
AM345_RS04420	COG1063	alcohol dehydrogenase
AM345_RS04445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AM345_RS04460	COG3734	2-keto-3-deoxy-galactonokinase
AM345_RS04465	COG0800	Aldolase
AM345_RS04470	COG0837	glucose binding
AM345_RS04470	COG1737	Transcriptional regulator
AM345_RS04495	COG1484	DNA-dependent DNA replication
AM345_RS04510	COG2966	Psort location CytoplasmicMembrane, score
AM345_RS04525	COG2197	response regulator
AM345_RS04530	COG2197	response regulator
AM345_RS04535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM345_RS04540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM345_RS04545	COG4114	ferric iron reductase
AM345_RS04550	COG3706	GGDEF domain
AM345_RS04580	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM345_RS04585	COG0456	acetyltransferase
AM345_RS04590	COG1011	Hydrolase
AM345_RS04600	COG2823	Periplasmic or secreted lipoprotein
AM345_RS04605	COG5487	UPF0391 membrane protein
AM345_RS04610	COG4667	esterase of the alpha-beta hydrolase superfamily
AM345_RS04615	COG0084	hydrolase, TatD family'
AM345_RS04645	COG3726	membrane protein affecting hemolysin expression
AM345_RS04655	COG0560	Phosphoserine phosphatase
AM345_RS04660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM345_RS04670	COG0488	(ABC) transporter
AM345_RS04680	COG0741	lytic transglycosylase activity
AM345_RS04700	COG2207	Transcriptional regulator
AM345_RS04700	COG3708	Transcriptional regulator
AM345_RS04705	COG3045	CreA protein
AM345_RS04710	COG0745	RESPONSE REGULATOR receiver
AM345_RS04715	COG2205	protein histidine kinase activity
AM345_RS04720	COG4452	Inner membrane protein CreD
AM345_RS04725	COG0745	RESPONSE REGULATOR receiver
AM345_RS04740	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM345_RS04750	COG0460	homoserine dehydrogenase
AM345_RS04750	COG0527	aspartate kinase activity
AM345_RS04760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM345_RS04770	COG1115	amino acid carrier protein
AM345_RS04775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM345_RS04780	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM345_RS04785	COG0477	Major facilitator Superfamily
AM345_RS04790	COG1584	GPR1 FUN34 yaaH family protein
AM345_RS04805	COG0583	DNA-binding transcription factor activity
AM345_RS04840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM345_RS04845	COG3539	Fimbrial protein
AM345_RS04855	COG3188	usher protein
AM345_RS04870	COG3539	Fimbrial protein
AM345_RS04875	COG3121	Chaperone
AM345_RS04895	COG0583	DNA-binding transcription factor activity
AM345_RS04910	COG0196	riboflavin kinase activity
AM345_RS04920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM345_RS04925	COG1047	Peptidyl-prolyl cis-trans
AM345_RS04940	COG0583	DNA-binding transcription factor activity
AM345_RS04950	COG2828	Protein conserved in bacteria
AM345_RS04955	COG0471	metal ion transport
AM345_RS04960	COG0471	metal ion transport
AM345_RS04965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM345_RS04975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM345_RS05050	COG0505	Belongs to the CarA family
AM345_RS05105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM345_RS05115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM345_RS05120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM345_RS05135	COG3493	citrate carrier protein
AM345_RS05145	COG0564	pseudouridine synthase activity
AM345_RS05155	COG0417	DNA replication proofreading
AM345_RS05165	COG0235	Class ii aldolase
AM345_RS05185	COG0586	Pfam SNARE associated Golgi protein
AM345_RS05195	COG1178	ABC-type Fe3 transport system permease component
AM345_RS05215	COG2814	Major facilitator Superfamily
AM345_RS05220	COG2271	Major facilitator Superfamily
AM345_RS05225	COG0583	DNA-binding transcription factor activity
AM345_RS05235	COG0738	Major facilitator superfamily
AM345_RS05285	COG0028	Belongs to the TPP enzyme family
AM345_RS05315	COG0768	penicillin binding
AM345_RS05320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM345_RS05325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM345_RS05340	COG0772	Belongs to the SEDS family
AM345_RS05355	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM345_RS05365	COG0849	cell division
AM345_RS05370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM345_RS05390	COG0494	nUDIX hydrolase
AM345_RS05415	COG1459	type II secretion system
AM345_RS05420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM345_RS05425	COG4969	Belongs to the N-Me-Phe pilin family
AM345_RS05440	COG3725	Membrane protein required for beta-lactamase induction
AM345_RS05445	COG3940	Belongs to the glycosyl hydrolase 43 family
AM345_RS05450	COG2211	Major facilitator Superfamily
AM345_RS05455	COG1113	amino acid transport
AM345_RS05460	COG2186	Transcriptional regulator
AM345_RS05465	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM345_RS05470	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM345_RS05475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM345_RS05490	COG3064	Membrane
AM345_RS05495	COG1049	propionate catabolic process, 2-methylcitrate cycle
AM345_RS05515	COG0545	Peptidyl-prolyl cis-trans isomerase
AM345_RS05530	COG2132	Multicopper oxidase
AM345_RS05535	COG4993	Dehydrogenase
AM345_RS05545	COG0288	reversible hydration of carbon dioxide
AM345_RS05555	COG1131	(ABC) transporter
AM345_RS05560	COG0842	Transport permease protein
AM345_RS05565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS05570	COG0726	polysaccharide deacetylase
AM345_RS05575	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM345_RS05590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM345_RS05615	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM345_RS05620	COG1643	Atp-dependent helicase
AM345_RS05630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM345_RS05635	COG4774	siderophore transport
AM345_RS05640	COG1120	ATPase activity
AM345_RS05645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM345_RS05650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS05670	COG2860	membrane
AM345_RS05675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM345_RS05695	COG3835	regulator
AM345_RS05715	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM345_RS05720	COG0024	Methionine aminopeptidase
AM345_RS05745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM345_RS05760	COG0575	Belongs to the CDS family
AM345_RS05765	COG0750	zinc metalloprotease
AM345_RS05820	COG1982	Orn Lys Arg decarboxylase major
AM345_RS05825	COG0346	lactoylglutathione lyase activity
AM345_RS05830	COG0037	tRNA processing
AM345_RS05835	COG4568	rho-dependent transcription termination
AM345_RS05850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM345_RS05855	COG3015	lipoprotein NlpE involved in copper resistance
AM345_RS05865	COG1720	tRNA m6t6A37 methyltransferase activity
AM345_RS05875	COG1464	Belongs to the NlpA lipoprotein family
AM345_RS05880	COG2011	ABC-type metal ion transport system permease component
AM345_RS05890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM345_RS05925	COG0656	L-ascorbic acid biosynthetic process
AM345_RS05930	COG0583	DNA-binding transcription factor activity
AM345_RS05935	COG2814	Major facilitator Superfamily
AM345_RS05945	COG2226	methyltransferase
AM345_RS05950	COG1388	LysM domain
AM345_RS05950	COG0741	lytic transglycosylase activity
AM345_RS05960	COG2226	methyltransferase
AM345_RS05970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM345_RS05980	COG0583	DNA-binding transcription factor activity
AM345_RS05990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM345_RS05995	COG1960	acyl-CoA dehydrogenase activity
AM345_RS06005	COG0121	glutamine amidotransferase
AM345_RS06010	COG3034	peptidoglycan biosynthetic process
AM345_RS06030	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM345_RS06035	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM345_RS06050	COG2991	Protein conserved in bacteria
AM345_RS06065	COG0454	-acetyltransferase
AM345_RS06080	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM345_RS06100	COG1045	serine acetyltransferase
AM345_RS06115	COG0438	transferase activity, transferring glycosyl groups
AM345_RS06115	COG0297	glycogen (starch) synthase activity
AM345_RS06120	COG0438	transferase activity, transferring glycosyl groups
AM345_RS06125	COG0463	Glycosyl transferase, family 2
AM345_RS06145	COG1596	polysaccharide export
AM345_RS06155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM345_RS06170	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS06180	COG0583	DNA-binding transcription factor activity
AM345_RS06195	COG1802	Transcriptional regulator
AM345_RS06200	COG1113	amino acid transport
AM345_RS06205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM345_RS06210	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS06215	COG0579	oxidoreductase
AM345_RS06235	COG3188	usher protein
AM345_RS06240	COG3121	Chaperone
AM345_RS06300	COG0791	NLP P60 protein
AM345_RS06320	COG3639	organic phosphonate transmembrane transporter activity
AM345_RS06330	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM345_RS06355	COG3188	usher protein
AM345_RS06375	COG2271	Major facilitator Superfamily
AM345_RS06380	COG0583	DNA-binding transcription factor activity
AM345_RS06385	COG0765	amino acid transport
AM345_RS06390	COG0765	amino acid transport
AM345_RS06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS06415	COG0833	amino acid
AM345_RS06420	COG2040	homocysteine
AM345_RS06425	COG4521	taurine ABC transporter
AM345_RS06430	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM345_RS06435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM345_RS06440	COG2175	clavaminate synthase activity
AM345_RS06455	COG1943	Transposase
AM345_RS06460	COG0113	porphobilinogen synthase activity
AM345_RS06465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM345_RS06475	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM345_RS06510	COG1785	Belongs to the alkaline phosphatase family
AM345_RS06520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM345_RS06530	COG3416	Protein conserved in bacteria
AM345_RS06535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM345_RS06545	COG4126	flavin adenine dinucleotide binding
AM345_RS06560	COG1940	carbohydrate kinase activity
AM345_RS06565	COG0419	ATPase involved in DNA repair
AM345_RS06570	COG0420	3'-5' exonuclease activity
AM345_RS06595	COG0366	Alpha amylase catalytic
AM345_RS06600	COG0583	DNA-binding transcription factor activity
AM345_RS06605	COG1335	isochorismatase
AM345_RS06615	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AM345_RS06620	COG0450	alkyl hydroperoxide reductase
AM345_RS06640	COG1862	Preprotein translocase
AM345_RS06650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM345_RS06665	COG3248	Nucleoside-binding outer membrane protein
AM345_RS06670	COG4238	major outer membrane lipoprotein
AM345_RS06680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM345_RS06680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM345_RS06695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM345_RS06700	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM345_RS06705	COG0667	Aldo Keto reductase
AM345_RS06715	COG0142	geranyltranstransferase activity
AM345_RS06740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM345_RS06755	COG2831	hemolysin activation secretion protein
AM345_RS06760	COG0736	holo-[acyl-carrier-protein] synthase activity
AM345_RS06770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM345_RS06775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM345_RS06785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM345_RS06800	COG1136	(ABC) transporter
AM345_RS06810	COG2177	Part of the ABC transporter FtsEX involved in
AM345_RS06840	COG2814	Major facilitator Superfamily
AM345_RS06855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM345_RS06860	COG1845	cytochrome c oxidase, subunit III
AM345_RS06865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM345_RS06870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM345_RS06875	COG2223	nitrite transmembrane transporter activity
AM345_RS06880	COG3056	Lipoprotein
AM345_RS06890	COG0271	Belongs to the BolA IbaG family
AM345_RS06920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM345_RS06925	COG0776	regulation of translation
AM345_RS06930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM345_RS06940	COG1555	photosystem II stabilization
AM345_RS06945	COG0824	Thioesterase
AM345_RS06955	COG4533	DNA binding
AM345_RS06970	COG1522	sequence-specific DNA binding
AM345_RS06975	COG1132	(ABC) transporter
AM345_RS06980	COG1132	(ABC) transporter
AM345_RS06985	COG0347	Belongs to the P(II) protein family
AM345_RS06990	COG0004	ammonium transporteR
AM345_RS06995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM345_RS07000	COG0583	DNA-binding transcription factor activity
AM345_RS07005	COG1946	Acyl-CoA thioesterase
AM345_RS07010	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM345_RS07015	COG3695	enzyme binding
AM345_RS07045	COG2364	Membrane
AM345_RS07050	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM345_RS07055	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM345_RS07065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM345_RS07085	COG0110	maltose O-acetyltransferase activity
AM345_RS07100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM345_RS07105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS07110	COG1309	transcriptional regulator
AM345_RS07115	COG3264	Mechanosensitive ion channel
AM345_RS07115	COG1196	nuclear chromosome segregation
AM345_RS07125	COG3923	Primosomal replication protein n
AM345_RS07130	COG2832	Protein of unknown function (DUF454)
AM345_RS07170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM345_RS07175	COG4651	solute:proton antiporter activity
AM345_RS07175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM345_RS07180	COG2223	nitrite transmembrane transporter activity
AM345_RS07190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM345_RS07195	COG3735	TraB family
AM345_RS07210	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM345_RS07215	COG0330	HflC and HflK could
AM345_RS07220	COG4619	ABC transporter
AM345_RS07225	COG0390	transport system, permease component
AM345_RS07230	COG3118	belongs to the thioredoxin family
AM345_RS07235	COG0300	oxidoreductase activity
AM345_RS07240	COG2755	lipolytic protein G-D-S-L family
AM345_RS07245	COG4181	ATPase activity
AM345_RS07250	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM345_RS07265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM345_RS07270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM345_RS07285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM345_RS07295	COG2501	S4 domain
AM345_RS07335	COG0583	DNA-binding transcription factor activity
AM345_RS07350	COG1560	Kdo2-lipid A biosynthetic process
AM345_RS07360	COG1902	pentaerythritol trinitrate reductase activity
AM345_RS07365	COG3710	Transcriptional regulator
AM345_RS07375	COG0531	amino acid
AM345_RS07380	COG1982	Orn Lys Arg decarboxylase major
AM345_RS07385	COG3104	oligopeptide transport
AM345_RS07395	COG0402	S-adenosylhomocysteine deaminase activity
AM345_RS07400	COG0549	Belongs to the carbamate kinase family
AM345_RS07405	COG1304	FMN binding
AM345_RS07410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM345_RS07420	COG0666	response to abiotic stimulus
AM345_RS07430	COG0583	DNA-binding transcription factor activity
AM345_RS07445	COG1566	PFAM secretion protein HlyD family protein
AM345_RS07465	COG1473	amidohydrolase
AM345_RS07470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS07475	COG0667	Aldo Keto reductase
AM345_RS07520	COG0531	amino acid
AM345_RS07530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM345_RS07535	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS07545	COG1252	NADH dehydrogenase
AM345_RS07560	COG1113	amino acid transport
AM345_RS07565	COG0668	transmembrane transport
AM345_RS07570	COG0477	Major facilitator Superfamily
AM345_RS07585	COG0778	Nitroreductase
AM345_RS07590	COG2315	Protein conserved in bacteria
AM345_RS07620	COG3698	Phosphodiester glycosidase
AM345_RS07650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM345_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS07680	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS07685	COG1129	ABC transporter
AM345_RS07695	COG1879	ABC-type sugar transport system periplasmic component
AM345_RS07700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM345_RS07705	COG2390	Transcriptional regulator
AM345_RS07715	COG3959	Transketolase, thiamine diphosphate binding domain
AM345_RS07720	COG3958	Transketolase
AM345_RS07725	COG4771	TonB-dependent receptor
AM345_RS07735	COG2382	esterase
AM345_RS07740	COG3251	PFAM MbtH domain protein
AM345_RS07745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM345_RS07745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM345_RS07750	COG1120	ATPase activity
AM345_RS07755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS07760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS07775	COG4592	Periplasmic binding protein
AM345_RS07780	COG1169	isochorismate synthase
AM345_RS07785	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM345_RS07790	COG3433	isochorismatase activity
AM345_RS07790	COG1535	isochorismatase
AM345_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS07805	COG1966	Carbon starvation protein
AM345_RS07810	COG2879	small protein
AM345_RS07830	COG1129	ABC transporter
AM345_RS07835	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS07860	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AM345_RS07870	COG0436	Aminotransferase
AM345_RS07875	COG1475	DNA binding
AM345_RS07880	COG3969	phosphoadenosine phosphosulfate
AM345_RS07885	COG0583	DNA-binding transcription factor activity
AM345_RS07895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM345_RS07905	COG3634	alkyl hydroperoxide reductase activity
AM345_RS07915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM345_RS07920	COG3719	Belongs to the RNase T2 family
AM345_RS07925	COG3069	C4-dicarboxylate transmembrane transporter activity
AM345_RS07945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM345_RS07960	COG0583	DNA-binding transcription factor activity
AM345_RS07975	COG1686	Belongs to the peptidase S11 family
AM345_RS07980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM345_RS07985	COG0772	Belongs to the SEDS family
AM345_RS07990	COG0768	penicillin binding
AM345_RS08000	COG0799	negative regulation of ribosome biogenesis
AM345_RS08005	COG0406	alpha-ribazole phosphatase activity
AM345_RS08015	COG1466	dna polymerase III delta subunit
AM345_RS08030	COG2888	peptidyl-tyrosine sulfation
AM345_RS08040	COG2831	hemolysin activation secretion protein
AM345_RS08045	COG1126	abc transporter atp-binding protein
AM345_RS08050	COG0765	amino acid transport
AM345_RS08055	COG0765	amino acid transport
AM345_RS08085	COG1702	phosphate starvation-inducible protein PhoH
AM345_RS08095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM345_RS08135	COG0367	asparagine synthase
AM345_RS08140	COG0647	UMP catabolic process
AM345_RS08145	COG1846	Transcriptional regulator
AM345_RS08145	COG1940	carbohydrate kinase activity
AM345_RS08150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM345_RS08195	COG1053	succinate dehydrogenase
AM345_RS08200	COG0583	DNA-binding transcription factor activity
AM345_RS08205	COG0735	belongs to the Fur family
AM345_RS08220	COG0596	Alpha beta hydrolase
AM345_RS08230	COG0033	Phosphoglucomutase
AM345_RS08235	COG0745	RESPONSE REGULATOR receiver
AM345_RS08240	COG2205	protein histidine kinase activity
AM345_RS08270	COG0415	Belongs to the DNA photolyase family
AM345_RS08280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM345_RS08285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM345_RS08290	COG1984	allophanate hydrolase subunit 2
AM345_RS08320	COG0372	Belongs to the citrate synthase family
AM345_RS08335	COG2009	succinate dehydrogenase
AM345_RS08340	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM345_RS08345	COG1053	succinate dehydrogenase
AM345_RS08350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM345_RS08355	COG0567	Dehydrogenase, E1 component
AM345_RS08360	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM345_RS08375	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM345_RS08385	COG1271	oxidase subunit
AM345_RS08390	COG1294	oxidase, subunit
AM345_RS08395	COG4890	Cyd operon protein YbgT
AM345_RS08400	COG3790	cyd operon protein YbgE
AM345_RS08405	COG0824	Thioesterase
AM345_RS08410	COG0811	peptide transport
AM345_RS08415	COG0848	biopolymer transport protein
AM345_RS08420	COG3064	Membrane
AM345_RS08430	COG2885	chlorophyll binding
AM345_RS08435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM345_RS08475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM345_RS08485	COG1230	cation diffusion facilitator family transporter
AM345_RS08495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM345_RS08510	COG2017	converts alpha-aldose to the beta-anomer
AM345_RS08520	COG1085	galactose-1-phosphate uridylyltransferase
AM345_RS08525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM345_RS08530	COG1119	ATPase activity
AM345_RS08535	COG2005	Transcriptional regulator
AM345_RS08535	COG3585	molybdate ion transport
AM345_RS08545	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM345_RS08550	COG4149	molybdate abc transporter
AM345_RS08560	COG0561	phosphatase activity
AM345_RS08585	COG2200	EAL domain
AM345_RS08590	COG0789	Transcriptional regulator
AM345_RS08615	COG1595	DNA-templated transcription, initiation
AM345_RS08625	COG4677	pectinesterase activity
AM345_RS08665	COG1881	PFAM PEBP family protein
AM345_RS08670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM345_RS08685	COG2226	methyltransferase
AM345_RS08710	COG0745	RESPONSE REGULATOR receiver
AM345_RS08735	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM345_RS08745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM345_RS08750	COG0314	molybdopterin synthase activity
AM345_RS08755	COG0670	Belongs to the BI1 family
AM345_RS08760	COG0392	lysyltransferase activity
AM345_RS08765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM345_RS08770	COG3568	Endonuclease Exonuclease Phosphatase
AM345_RS08780	COG0842	Transport permease protein
AM345_RS08785	COG0842	Transport permease protein
AM345_RS08790	COG1131	(ABC) transporter
AM345_RS08800	COG1309	transcriptional regulator
AM345_RS08805	COG0513	Belongs to the DEAD box helicase family
AM345_RS08815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM345_RS08825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM345_RS08835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM345_RS08845	COG0668	transmembrane transport
AM345_RS08850	COG1126	abc transporter atp-binding protein
AM345_RS08855	COG0765	amino acid transport
AM345_RS08860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS08875	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM345_RS08880	COG2194	sulfuric ester hydrolase activity
AM345_RS08890	COG1321	iron dependent repressor
AM345_RS08895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM345_RS08900	COG0667	Aldo Keto reductase
AM345_RS08905	COG2723	6-phospho-beta-galactosidase activity
AM345_RS08910	COG2188	Transcriptional regulator
AM345_RS08915	COG1376	ErfK ybiS ycfS ynhG family protein
AM345_RS08925	COG0488	(ABC) transporter
AM345_RS08940	COG2271	Major facilitator Superfamily
AM345_RS08945	COG1609	Transcriptional regulator
AM345_RS08955	COG0561	phosphatase activity
AM345_RS08960	COG1882	Formate acetyltransferase
AM345_RS08965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM345_RS08970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM345_RS08975	COG0303	'Molybdopterin
AM345_RS08985	COG1446	asparaginase
AM345_RS08995	COG0747	negative chemotaxis
AM345_RS09020	COG2133	pyrroloquinoline quinone binding
AM345_RS09025	COG0625	glutathione transferase activity
AM345_RS09030	COG1686	Belongs to the peptidase S11 family
AM345_RS09035	COG1349	DNA-binding transcription factor activity
AM345_RS09040	COG0671	phosphoesterase, PA-phosphatase related
AM345_RS09050	COG2814	Major facilitator Superfamily
AM345_RS09055	COG0561	phosphatase activity
AM345_RS09060	COG0738	Major facilitator superfamily
AM345_RS09065	COG3226	Transcriptional regulator
AM345_RS09070	COG0300	oxidoreductase activity
AM345_RS09110	COG0778	Nitroreductase
AM345_RS09125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM345_RS09130	COG3842	ATPase activity
AM345_RS09135	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM345_RS09140	COG1177	transmembrane transport
AM345_RS09150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM345_RS09155	COG0745	RESPONSE REGULATOR receiver
AM345_RS09160	COG5002	protein histidine kinase activity
AM345_RS09165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS09170	COG4160	amino acid transport
AM345_RS09175	COG4215	(ABC) transporter
AM345_RS09180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS09185	COG1126	abc transporter atp-binding protein
AM345_RS09195	COG2067	long-chain fatty acid transport protein
AM345_RS09205	COG4251	negative regulation of phosphorylation
AM345_RS09205	COG3706	GGDEF domain
AM345_RS09205	COG2203	Gaf domain
AM345_RS09205	COG5001	Diguanylate cyclase
AM345_RS09210	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM345_RS09215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM345_RS09220	COG0702	epimerase
AM345_RS09225	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM345_RS09230	COG0028	Belongs to the TPP enzyme family
AM345_RS09250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM345_RS09260	COG2431	L-lysine efflux transmembrane transporter activity
AM345_RS09270	COG3593	DNA synthesis involved in DNA repair
AM345_RS09275	COG2990	Protein conserved in bacteria
AM345_RS09280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS09290	COG1278	Cold shock
AM345_RS09300	COG0542	response to heat
AM345_RS09320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM345_RS09325	COG4988	ABC transporter
AM345_RS09330	COG0492	ferredoxin-NADP+ reductase activity
AM345_RS09355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM345_RS09365	COG0243	molybdopterin cofactor binding
AM345_RS09370	COG0437	4 iron, 4 sulfur cluster binding
AM345_RS09375	COG3302	dmso reductase anchor subunit
AM345_RS09380	COG0477	Major facilitator Superfamily
AM345_RS09385	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM345_RS09390	COG1882	Formate acetyltransferase
AM345_RS09395	COG2116	formate transmembrane transporter activity
AM345_RS09400	COG1944	ATP diphosphatase activity
AM345_RS09425	COG0539	negative regulation of cytoplasmic translation
AM345_RS09435	COG0658	competence protein
AM345_RS09435	COG2333	competence protein COMEC
AM345_RS09440	COG1132	(ABC) transporter
AM345_RS09450	COG3214	Protein conserved in bacteria
AM345_RS09455	COG2835	tetraacyldisaccharide 4'-kinase activity
AM345_RS09465	COG3173	Aminoglycoside phosphotransferase
AM345_RS09470	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM345_RS09475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM345_RS09485	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM345_RS09495	COG2989	Protein conserved in bacteria
AM345_RS09505	COG3108	Peptidase M15
AM345_RS09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM345_RS09515	COG1448	Aminotransferase
AM345_RS09520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM345_RS09540	COG0308	aminopeptidase N
AM345_RS09550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM345_RS09555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS09560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM345_RS09565	COG0431	NADPH-dependent FMN reductase
AM345_RS09580	COG3217	Mosc domain protein beta barrel domain protein
AM345_RS09580	COG0633	Ferredoxin
AM345_RS09590	COG0488	(ABC) transporter
AM345_RS09595	COG2995	paraquat-inducible protein a
AM345_RS09600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM345_RS09600	COG3008	intermembrane lipid transfer
AM345_RS09605	COG3009	Protein conserved in bacteria
AM345_RS09615	COG3130	regulation of translation
AM345_RS09625	COG1067	ATP-dependent peptidase activity
AM345_RS09645	COG3070	regulator of competence-specific genes
AM345_RS09650	COG1289	transmembrane transporter activity
AM345_RS09655	COG3304	Inner membrane component domain
AM345_RS09660	COG0210	DNA helicase
AM345_RS09670	COG1832	CoA-binding protein
AM345_RS09685	COG2274	protein secretion by the type I secretion system
AM345_RS09690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS09695	COG0438	transferase activity, transferring glycosyl groups
AM345_RS09725	COG0670	Belongs to the BI1 family
AM345_RS09740	COG0583	DNA-binding transcription factor activity
AM345_RS09755	COG0583	DNA-binding transcription factor activity
AM345_RS09810	COG0643	Histidine kinase
AM345_RS09810	COG2198	Histidine kinase
AM345_RS09815	COG0835	chemotaxis
AM345_RS09820	COG0840	transmembrane signaling receptor activity
AM345_RS09825	COG0840	transmembrane signaling receptor activity
AM345_RS09830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM345_RS09840	COG0745	RESPONSE REGULATOR receiver
AM345_RS09845	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AM345_RS09850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM345_RS09855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM345_RS09865	COG3418	PFAM FlgN family protein
AM345_RS09870	COG2747	anti-sigma28 factor FlgM
AM345_RS09880	COG1815	bacterial-type flagellum-dependent cell motility
AM345_RS09885	COG1558	bacterial-type flagellum-dependent cell motility
AM345_RS09890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM345_RS09905	COG4786	Flagellar basal body rod
AM345_RS09925	COG1256	bacterial-type flagellum assembly
AM345_RS09965	COG2814	Major facilitator Superfamily
AM345_RS09975	COG1414	Transcriptional regulator
AM345_RS09980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM345_RS09985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM345_RS10060	COG2882	bacterial-type flagellum organization
AM345_RS10065	COG1157	protein secretion by the type III secretion system
AM345_RS10075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM345_RS10085	COG1677	Flagellar hook-basal body complex protein FliE
AM345_RS10130	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AM345_RS10145	COG1191	sigma factor activity
AM345_RS10185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM345_RS10190	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS10195	COG4638	Rieske (2fe-2S)
AM345_RS10200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM345_RS10205	COG0473	3-isopropylmalate dehydrogenase activity
AM345_RS10210	COG0583	DNA-binding transcription factor activity
AM345_RS10215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM345_RS10220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM345_RS10225	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS10230	COG1917	Cupin 2, conserved barrel domain protein
AM345_RS10230	COG1396	sequence-specific DNA binding
AM345_RS10235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM345_RS10240	COG0174	glutamine synthetase
AM345_RS10250	COG0531	amino acid
AM345_RS10320	COG3729	General stress protein
AM345_RS10330	COG2233	PERMEase
AM345_RS10365	COG1309	transcriptional regulator
AM345_RS10380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM345_RS10385	COG0628	permease
AM345_RS10395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM345_RS10405	COG2822	iron ion transport
AM345_RS10415	COG1702	phosphate starvation-inducible protein PhoH
AM345_RS10435	COG1335	isochorismatase
AM345_RS10445	COG0583	DNA-binding transcription factor activity
AM345_RS10470	COG3381	protein complex oligomerization
AM345_RS10510	COG5645	(Lipo)protein
AM345_RS10525	COG1560	Kdo2-lipid A biosynthetic process
AM345_RS10570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM345_RS10580	COG0673	inositol 2-dehydrogenase activity
AM345_RS10590	COG2814	Major facilitator Superfamily
AM345_RS10595	COG0583	DNA-binding transcription factor activity
AM345_RS10600	COG1530	ribonuclease E activity
AM345_RS10620	COG1399	metal-binding, possibly nucleic acid-binding protein
AM345_RS10640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM345_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS10655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM345_RS10660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM345_RS10665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM345_RS10675	COG0470	DNA polymerase III
AM345_RS10680	COG0084	hydrolase, TatD family'
AM345_RS10685	COG1263	PTS System
AM345_RS10685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS10690	COG0537	adenosine 5'-monophosphoramidase activity
AM345_RS10695	COG5633	Lipoprotein
AM345_RS10730	COG1252	NADH dehydrogenase
AM345_RS10735	COG3134	Outer membrane lipoprotein
AM345_RS10745	COG1309	transcriptional regulator
AM345_RS10755	COG1376	ErfK ybiS ycfS ynhG family protein
AM345_RS10755	COG1388	LysM domain
AM345_RS10760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM345_RS10765	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM345_RS10770	COG1136	(ABC) transporter
AM345_RS10775	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM345_RS10785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM345_RS10790	COG0318	PFAM AMP-dependent synthetase and ligase
AM345_RS10800	COG1177	transmembrane transport
AM345_RS10820	COG1943	Transposase
AM345_RS10830	COG2850	peptidyl-arginine hydroxylation
AM345_RS10845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM345_RS10865	COG1187	pseudouridine synthase activity
AM345_RS10870	COG0538	isocitrate dehydrogenase activity
AM345_RS10880	COG1403	HNH endonuclease
AM345_RS10885	COG3272	Protein of unknown function (DUF1722)
AM345_RS10890	COG0789	Transcriptional regulator
AM345_RS10900	COG4977	sequence-specific DNA binding
AM345_RS10905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS10930	COG3122	Protein conserved in bacteria
AM345_RS10945	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM345_RS10950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS10955	COG3477	response to acidic pH
AM345_RS10960	COG0012	GTP binding
AM345_RS10975	COG0659	secondary active sulfate transmembrane transporter activity
AM345_RS11010	COG2890	protein-(glutamine-N5) methyltransferase activity
AM345_RS11030	COG0387	Pfam Sodium calcium exchanger
AM345_RS11035	COG4572	Cation transport regulator
AM345_RS11040	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM345_RS11050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM345_RS11055	COG3707	response regulator
AM345_RS11060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM345_RS11070	COG1116	anion transmembrane transporter activity
AM345_RS11075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM345_RS11075	COG2146	nitrite reductase [NAD(P)H] activity
AM345_RS11080	COG0243	molybdopterin cofactor binding
AM345_RS11085	COG4932	domain protein
AM345_RS11090	COG2197	response regulator
AM345_RS11095	COG3850	Histidine kinase
AM345_RS11100	COG2223	nitrite transmembrane transporter activity
AM345_RS11105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM345_RS11110	COG1140	nitrate reductase beta subunit
AM345_RS11115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM345_RS11120	COG2181	nitrate reductase activity
AM345_RS11130	COG1522	sequence-specific DNA binding
AM345_RS11175	COG0788	formyltetrahydrofolate deformylase activity
AM345_RS11185	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM345_RS11190	COG0745	RESPONSE REGULATOR receiver
AM345_RS11195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM345_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS11210	COG1454	alcohol dehydrogenase
AM345_RS11215	COG2095	MarC family integral membrane protein
AM345_RS11225	COG0601	transmembrane transport
AM345_RS11230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM345_RS11235	COG0444	Belongs to the ABC transporter superfamily
AM345_RS11245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM345_RS11270	COG1917	Cupin 2, conserved barrel domain protein
AM345_RS11275	COG0823	Involved in the tonB-independent uptake of proteins
AM345_RS11315	COG2135	peptidase activity
AM345_RS11320	COG2350	Protein conserved in bacteria
AM345_RS11325	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM345_RS11330	COG3001	Fructosamine kinase
AM345_RS11340	COG1105	Belongs to the carbohydrate kinase PfkB family
AM345_RS11345	COG3137	Salt-induced outer membrane protein
AM345_RS11380	COG2135	peptidase activity
AM345_RS11400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM345_RS11410	COG0072	phenylalanine-tRNA ligase activity
AM345_RS11410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM345_RS11430	COG0583	DNA-binding transcription factor activity
AM345_RS11450	COG0386	Belongs to the glutathione peroxidase family
AM345_RS11460	COG0791	NLP P60 protein
AM345_RS11470	COG4256	Hemin uptake protein
AM345_RS11475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM345_RS11490	COG0574	Belongs to the PEP-utilizing enzyme family
AM345_RS11490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM345_RS11500	COG0628	permease
AM345_RS11505	COG0247	lactate metabolic process
AM345_RS11505	COG0277	FAD linked oxidase domain protein
AM345_RS11510	COG2050	protein possibly involved in aromatic compounds catabolism
AM345_RS11515	COG3422	double-strand break repair
AM345_RS11520	COG2261	transglycosylase associated protein
AM345_RS11535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM345_RS11540	COG0316	Belongs to the HesB IscA family
AM345_RS11545	COG0719	Fe-S assembly protein
AM345_RS11550	COG0396	ATPase activity
AM345_RS11555	COG0719	Fe-S assembly protein
AM345_RS11570	COG1376	ErfK ybiS ycfS ynhG family protein
AM345_RS11595	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM345_RS11595	COG1082	Xylose isomerase domain protein TIM barrel
AM345_RS11600	COG2271	Major facilitator Superfamily
AM345_RS11605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM345_RS11615	COG1120	ATPase activity
AM345_RS11620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS11625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM345_RS11650	COG0583	DNA-binding transcription factor activity
AM345_RS11655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS11675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM345_RS11680	COG1116	anion transmembrane transporter activity
AM345_RS11690	COG4774	siderophore transport
AM345_RS11695	COG1120	ATPase activity
AM345_RS11700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS11705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS11725	COG0765	amino acid transport
AM345_RS11730	COG1126	abc transporter atp-binding protein
AM345_RS11740	COG1473	amidohydrolase
AM345_RS11745	COG1683	Conserved Protein
AM345_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS11775	COG2378	regulation of single-species biofilm formation
AM345_RS11795	COG1280	lysine exporter protein (LysE YggA)
AM345_RS11805	COG3590	peptidase
AM345_RS11815	COG2207	Transcriptional regulator
AM345_RS11825	COG0251	oxidation-reduction process
AM345_RS11830	COG1309	transcriptional regulator
AM345_RS11850	COG0406	alpha-ribazole phosphatase activity
AM345_RS11855	COG1396	sequence-specific DNA binding
AM345_RS11860	COG0456	acetyltransferase
AM345_RS11880	COG3383	formate dehydrogenase (NAD+) activity
AM345_RS11885	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM345_RS11905	COG1175	transmembrane transport
AM345_RS11935	COG1138	Cytochrome C-type biogenesis protein
AM345_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS11965	COG2610	gluconate transmembrane transporter activity
AM345_RS11970	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM345_RS11980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM345_RS11990	COG0583	DNA-binding transcription factor activity
AM345_RS12005	COG4993	Dehydrogenase
AM345_RS12015	COG4608	Belongs to the ABC transporter superfamily
AM345_RS12020	COG0444	Belongs to the ABC transporter superfamily
AM345_RS12045	COG0346	lactoylglutathione lyase activity
AM345_RS12050	COG1349	DNA-binding transcription factor activity
AM345_RS12080	COG2233	PERMEase
AM345_RS12085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS12085	COG0493	'glutamate synthase
AM345_RS12090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS12095	COG0402	S-adenosylhomocysteine deaminase activity
AM345_RS12100	COG0493	'glutamate synthase
AM345_RS12100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS12105	COG2068	MobA-Related Protein
AM345_RS12110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM345_RS12115	COG3608	succinylglutamate desuccinylase aspartoacylase
AM345_RS12115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM345_RS12120	COG0549	Belongs to the carbamate kinase family
AM345_RS12130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM345_RS12135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM345_RS12140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM345_RS12145	COG3829	transcription factor binding
AM345_RS12155	COG2223	nitrite transmembrane transporter activity
AM345_RS12215	COG0534	Mate efflux family protein
AM345_RS12220	COG0307	riboflavin synthase, alpha
AM345_RS12225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM345_RS12230	COG2814	Major facilitator Superfamily
AM345_RS12235	COG0583	DNA-binding transcription factor activity
AM345_RS12250	COG2814	Major facilitator Superfamily
AM345_RS12260	COG2207	Transcriptional regulator
AM345_RS12260	COG3708	Transcriptional regulator
AM345_RS12265	COG0791	NLP P60 protein
AM345_RS12270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM345_RS12280	COG0346	lactoylglutathione lyase activity
AM345_RS12285	COG1902	pentaerythritol trinitrate reductase activity
AM345_RS12290	COG1309	transcriptional regulator
AM345_RS12295	COG3313	Fe-S protein
AM345_RS12300	COG4989	oxidoreductase activity
AM345_RS12305	COG2032	superoxide dismutase activity
AM345_RS12310	COG1289	transmembrane transporter activity
AM345_RS12315	COG1566	PFAM secretion protein HlyD family protein
AM345_RS12330	COG3706	GGDEF domain
AM345_RS12345	COG3895	Periplasmic Protein
AM345_RS12360	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM345_RS12365	COG0625	glutathione transferase activity
AM345_RS12380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM345_RS12390	COG4659	FMN binding
AM345_RS12425	COG2723	6-phospho-beta-galactosidase activity
AM345_RS12435	COG0673	inositol 2-dehydrogenase activity
AM345_RS12445	COG5562	phage envelope protein
AM345_RS12455	COG0789	Transcriptional regulator
AM345_RS12465	COG0425	Belongs to the sulfur carrier protein TusA family
AM345_RS12470	COG2391	methyltransferase activity
AM345_RS12480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM345_RS12485	COG1263	PTS System
AM345_RS12485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS12490	COG1609	Transcriptional regulator
AM345_RS12495	COG5339	Protein conserved in bacteria
AM345_RS12500	COG1482	cell wall glycoprotein biosynthetic process
AM345_RS12505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM345_RS12505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM345_RS12520	COG2205	protein histidine kinase activity
AM345_RS12530	COG0745	RESPONSE REGULATOR receiver
AM345_RS12535	COG3136	membrane protein required for alginate biosynthesis
AM345_RS12545	COG0531	amino acid
AM345_RS12565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM345_RS12570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM345_RS12585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM345_RS12590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM345_RS12605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM345_RS12610	COG1473	amidohydrolase
AM345_RS12620	COG0583	DNA-binding transcription factor activity
AM345_RS12625	COG2840	Smr protein MutS2
AM345_RS12630	COG1414	Transcriptional regulator
AM345_RS12640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM345_RS12645	COG0183	Belongs to the thiolase family
AM345_RS12655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM345_RS12660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM345_RS12695	COG4565	transcriptional regulatory protein
AM345_RS12700	COG3290	protein histidine kinase activity
AM345_RS12705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM345_RS12720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM345_RS12730	COG0679	Auxin Efflux Carrier
AM345_RS12760	COG0628	permease
AM345_RS12780	COG5001	Diguanylate cyclase
AM345_RS12780	COG3300	MHYT domain
AM345_RS12785	COG3591	Belongs to the peptidase S1B family
AM345_RS12805	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM345_RS12810	COG2814	Major facilitator Superfamily
AM345_RS12815	COG0583	DNA-binding transcription factor activity
AM345_RS12820	COG1940	carbohydrate kinase activity
AM345_RS12825	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM345_RS12840	COG3302	dmso reductase anchor subunit
AM345_RS12845	COG0437	4 iron, 4 sulfur cluster binding
AM345_RS12850	COG0243	molybdopterin cofactor binding
AM345_RS12865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM345_RS12880	COG2271	Major facilitator Superfamily
AM345_RS12885	COG4948	Mandelate Racemase Muconate Lactonizing
AM345_RS12890	COG1063	alcohol dehydrogenase
AM345_RS12895	COG0477	Major facilitator Superfamily
AM345_RS12900	COG0246	Mannitol dehydrogenase
AM345_RS12910	COG1802	Transcriptional regulator
AM345_RS12915	COG4221	oxidoreductase activity
AM345_RS12930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM345_RS12935	COG2223	nitrite transmembrane transporter activity
AM345_RS12955	COG2199	diguanylate cyclase activity
AM345_RS12955	COG2203	Gaf domain
AM345_RS12965	COG0583	DNA-binding transcription factor activity
AM345_RS12990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM345_RS13000	COG2814	Major facilitator Superfamily
AM345_RS13005	COG0697	spore germination
AM345_RS13020	COG1846	Transcriptional regulator
AM345_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS13060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM345_RS13070	COG3395	kinase activity
AM345_RS13075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM345_RS13080	COG1349	DNA-binding transcription factor activity
AM345_RS13085	COG0583	DNA-binding transcription factor activity
AM345_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS13105	COG2199	diguanylate cyclase activity
AM345_RS13130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM345_RS13135	COG2271	Major facilitator Superfamily
AM345_RS13140	COG3622	Belongs to the hyi family
AM345_RS13145	COG0235	Class ii aldolase
AM345_RS13150	COG3395	kinase activity
AM345_RS13155	COG1349	DNA-binding transcription factor activity
AM345_RS13185	COG0697	spore germination
AM345_RS13190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM345_RS13195	COG0477	Major facilitator Superfamily
AM345_RS13205	COG2070	2-Nitropropane dioxygenase
AM345_RS13210	COG2011	ABC-type metal ion transport system permease component
AM345_RS13230	COG4628	conserved protein (DUF2132)
AM345_RS13235	COG2207	Transcriptional regulator
AM345_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS13265	COG3729	General stress protein
AM345_RS13270	COG3685	Protein conserved in bacteria
AM345_RS13280	COG3685	Protein conserved in bacteria
AM345_RS13285	COG1271	oxidase subunit
AM345_RS13290	COG1294	oxidase, subunit
AM345_RS13315	COG2323	membrane
AM345_RS13325	COG3111	PFAM Bacterial OB fold (BOF) protein
AM345_RS13335	COG0626	cystathionine gamma-synthase activity
AM345_RS13355	COG2610	gluconate transmembrane transporter activity
AM345_RS13360	COG1312	Catalyzes the dehydration of D-mannonate
AM345_RS13365	COG0401	homolog of Blt101
AM345_RS13375	COG4529	Protein conserved in bacteria
AM345_RS13390	COG2814	Major facilitator Superfamily
AM345_RS13405	COG0745	RESPONSE REGULATOR receiver
AM345_RS13405	COG4191	Histidine kinase
AM345_RS13405	COG2205	protein histidine kinase activity
AM345_RS13415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM345_RS13420	COG0588	phosphoglycerate mutase activity
AM345_RS13470	COG2814	Major facilitator Superfamily
AM345_RS13480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM345_RS13490	COG0765	amino acid transport
AM345_RS13550	COG1953	Uracil, thiamine, allantoin
AM345_RS13555	COG0402	S-adenosylhomocysteine deaminase activity
AM345_RS13560	COG2351	hydroxyisourate hydrolase activity
AM345_RS13570	COG2233	PERMEase
AM345_RS13575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM345_RS13605	COG0454	-acetyltransferase
AM345_RS13610	COG0668	transmembrane transport
AM345_RS13705	COG2815	serine threonine protein kinase
AM345_RS13705	COG0515	serine threonine protein kinase
AM345_RS13840	COG1649	PFAM Uncharacterised BCR, COG1649
AM345_RS13845	COG2070	2-Nitropropane dioxygenase
AM345_RS13850	COG0583	DNA-binding transcription factor activity
AM345_RS13885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM345_RS13890	COG1116	anion transmembrane transporter activity
AM345_RS13895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM345_RS13900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM345_RS13905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM345_RS13910	COG0076	glutamate decarboxylase activity
AM345_RS13920	COG2205	protein histidine kinase activity
AM345_RS13990	COG0583	DNA-binding transcription factor activity
AM345_RS14000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM345_RS14005	COG1309	transcriptional regulator
AM345_RS14030	COG2814	Major facilitator Superfamily
AM345_RS14040	COG0583	DNA-binding transcription factor activity
AM345_RS14050	COG0243	molybdopterin cofactor binding
AM345_RS14055	COG1271	oxidase subunit
AM345_RS14060	COG1294	oxidase, subunit
AM345_RS14070	COG3781	membrane
AM345_RS14075	COG2837	iron assimilation
AM345_RS14090	COG1764	response to oxidative stress
AM345_RS14115	COG1609	Transcriptional regulator
AM345_RS14135	COG0488	(ABC) transporter
AM345_RS14145	COG1064	alcohol dehydrogenase
AM345_RS14150	COG0747	negative chemotaxis
AM345_RS14160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM345_RS14170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS14180	COG2814	Major facilitator Superfamily
AM345_RS14240	COG2864	formate dehydrogenase
AM345_RS14245	COG0437	4 iron, 4 sulfur cluster binding
AM345_RS14255	COG0697	spore germination
AM345_RS14270	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM345_RS14280	COG3485	protocatechuate 3,4-dioxygenase
AM345_RS14285	COG4829	muconolactone delta-isomerase
AM345_RS14290	COG4948	Mandelate Racemase Muconate Lactonizing
AM345_RS14300	COG1414	Transcriptional regulator
AM345_RS14320	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM345_RS14325	COG1140	nitrate reductase beta subunit
AM345_RS14330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM345_RS14335	COG2181	nitrate reductase activity
AM345_RS14340	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM345_RS14345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM345_RS14370	COG0625	glutathione transferase activity
AM345_RS14380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS14385	COG1126	abc transporter atp-binding protein
AM345_RS14400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS14405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS14410	COG1473	amidohydrolase
AM345_RS14415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS14445	COG4772	TonB-dependent receptor
AM345_RS14450	COG3691	Protein conserved in bacteria
AM345_RS14455	COG2130	NADP-dependent
AM345_RS14465	COG1247	-acetyltransferase
AM345_RS14470	COG3238	Protein conserved in bacteria
AM345_RS14480	COG0747	negative chemotaxis
AM345_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS14490	COG2267	carboxylic ester hydrolase activity
AM345_RS14510	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS14515	COG1177	transmembrane transport
AM345_RS14520	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM345_RS14525	COG3842	ATPase activity
AM345_RS14530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM345_RS14535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM345_RS14545	COG1271	oxidase subunit
AM345_RS14550	COG1294	oxidase, subunit
AM345_RS14565	COG0826	peptidase U32
AM345_RS14570	COG1396	sequence-specific DNA binding
AM345_RS14575	COG3135	benzoate transporter
AM345_RS14580	COG2207	Transcriptional regulator
AM345_RS14580	COG3708	Transcriptional regulator
AM345_RS14585	COG0697	spore germination
AM345_RS14595	COG0747	negative chemotaxis
AM345_RS14600	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM345_RS14605	COG0500	methyltransferase
AM345_RS14610	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM345_RS14615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM345_RS14620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM345_RS14640	COG0436	Aminotransferase
AM345_RS14645	COG1823	symporter activity
AM345_RS14650	COG1335	isochorismatase
AM345_RS14655	COG0583	DNA-binding transcription factor activity
AM345_RS14660	COG2272	Belongs to the type-B carboxylesterase lipase family
AM345_RS14665	COG5383	Protein conserved in bacteria
AM345_RS14670	COG3485	protocatechuate 3,4-dioxygenase
AM345_RS14675	COG3485	protocatechuate 3,4-dioxygenase
AM345_RS14680	COG0583	DNA-binding transcription factor activity
AM345_RS14720	COG3038	cytochrome b561
AM345_RS14755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM345_RS14760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM345_RS14765	COG1113	amino acid transport
AM345_RS14770	COG2988	succinylglutamate desuccinylase activity
AM345_RS14775	COG3724	N-succinylarginine dihydrolase activity
AM345_RS14780	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS14785	COG3138	arginine N-succinyltransferase
AM345_RS14790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM345_RS14795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM345_RS14820	COG4122	O-methyltransferase activity
AM345_RS14825	COG1643	Atp-dependent helicase
AM345_RS14840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM345_RS14845	COG3327	negative regulation of DNA-templated transcription, initiation
AM345_RS14850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM345_RS14855	COG0183	Belongs to the thiolase family
AM345_RS14860	COG2050	protein possibly involved in aromatic compounds catabolism
AM345_RS14865	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM345_RS14870	COG1024	Enoyl-CoA hydratase
AM345_RS14875	COG1024	Enoyl-CoA hydratase
AM345_RS14880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM345_RS14885	COG2151	metal-sulfur cluster biosynthetic enzyme
AM345_RS14890	COG3396	Phenylacetate-CoA oxygenase
AM345_RS14895	COG3460	Phenylacetate-CoA oxygenase
AM345_RS14900	COG3396	Phenylacetate-CoA oxygenase
AM345_RS14905	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS14905	COG2030	dehydratase
AM345_RS14920	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS14925	COG2207	Transcriptional regulator
AM345_RS14930	COG3784	Protein of unknown function (DUF1318)
AM345_RS14940	COG2911	Protein conserved in bacteria
AM345_RS14945	COG0586	Pfam SNARE associated Golgi protein
AM345_RS14950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM345_RS14955	COG3187	Heat shock protein
AM345_RS14960	COG3042	response to heat
AM345_RS14965	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM345_RS14965	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM345_RS14965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM345_RS14965	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM345_RS14970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM345_RS14975	COG0589	response to stress
AM345_RS14980	COG3549	Plasmid maintenance system killer
AM345_RS14985	COG3093	addiction module antidote protein HigA
AM345_RS15000	COG0513	Belongs to the DEAD box helicase family
AM345_RS15015	COG0456	acetyltransferase
AM345_RS15025	COG1940	carbohydrate kinase activity
AM345_RS15030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM345_RS15055	COG4172	Belongs to the ABC transporter superfamily
AM345_RS15060	COG1349	DNA-binding transcription factor activity
AM345_RS15065	COG0673	inositol 2-dehydrogenase activity
AM345_RS15075	COG0693	protein deglycase activity
AM345_RS15115	COG4580	involved in the transport of maltose and maltodextrins
AM345_RS15120	COG2211	Major facilitator Superfamily
AM345_RS15125	COG3507	Belongs to the glycosyl hydrolase 43 family
AM345_RS15130	COG0656	L-ascorbic acid biosynthetic process
AM345_RS15145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS15155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM345_RS15170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS15180	COG4166	transmembrane transport
AM345_RS15185	COG2866	Carboxypeptidase
AM345_RS15190	COG4948	Mandelate Racemase Muconate Lactonizing
AM345_RS15195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM345_RS15200	COG3180	Ammonia monooxygenase
AM345_RS15225	COG3106	COG3106 Predicted ATPase
AM345_RS15235	COG1983	PspC domain protein
AM345_RS15245	COG1842	Phage shock protein A
AM345_RS15250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM345_RS15260	COG1473	amidohydrolase
AM345_RS15285	COG2135	peptidase activity
AM345_RS15295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM345_RS15425	COG5410	chromosome segregation
AM345_RS15430	COG3728	DNA packaging
AM345_RS15430	COG5484	DNA packaging
AM345_RS15490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM345_RS15655	COG4171	peptide transport system, permease
AM345_RS15665	COG4172	Belongs to the ABC transporter superfamily
AM345_RS15670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM345_RS15680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM345_RS15685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM345_RS15685	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM345_RS15700	COG1349	DNA-binding transcription factor activity
AM345_RS15710	COG0023	Translation Initiation Factor
AM345_RS15720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM345_RS15725	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM345_RS15730	COG0671	phosphoesterase, PA-phosphatase related
AM345_RS15740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM345_RS15775	COG0616	signal peptide processing
AM345_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS15785	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM345_RS15790	COG2207	Transcriptional regulator
AM345_RS15795	COG1472	Belongs to the glycosyl hydrolase 3 family
AM345_RS15800	COG2211	Major facilitator Superfamily
AM345_RS15810	COG5001	Diguanylate cyclase
AM345_RS15810	COG1716	ATPase activity
AM345_RS15815	COG1716	ATPase activity
AM345_RS15815	COG5001	Diguanylate cyclase
AM345_RS15820	COG0009	L-threonylcarbamoyladenylate synthase
AM345_RS15830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM345_RS15835	COG0512	Glutamine amidotransferase of anthranilate synthase
AM345_RS15835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM345_RS15840	COG0135	phosphoribosylanthranilate isomerase activity
AM345_RS15840	COG0134	indole-3-glycerol-phosphate synthase activity
AM345_RS15860	COG1063	alcohol dehydrogenase
AM345_RS15865	COG1566	PFAM secretion protein HlyD family protein
AM345_RS15880	COG0583	DNA-binding transcription factor activity
AM345_RS15885	COG3047	cAMP biosynthetic process
AM345_RS15890	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM345_RS15915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM345_RS15920	COG1988	membrane-bound metal-dependent
AM345_RS15925	COG1823	symporter activity
AM345_RS15935	COG0753	catalase activity
AM345_RS15945	COG1486	melibiose metabolic process
AM345_RS15950	COG1917	Cupin 2, conserved barrel domain protein
AM345_RS15950	COG2169	Transcriptional regulator
AM345_RS15955	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM345_RS15960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM345_RS15965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM345_RS15970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM345_RS15980	COG0322	excinuclease ABC activity
AM345_RS15985	COG3678	ATP-independent chaperone mediated protein folding
AM345_RS16005	COG3138	arginine N-succinyltransferase
AM345_RS16020	COG0708	Exodeoxyribonuclease III
AM345_RS16025	COG0398	Pfam SNARE associated Golgi protein
AM345_RS16030	COG0398	Pfam SNARE associated Golgi protein
AM345_RS16035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM345_RS16040	COG4134	Bacterial extracellular solute-binding protein
AM345_RS16045	COG4135	transport system, permease component
AM345_RS16050	COG4136	ATPase activity
AM345_RS16055	COG2897	thiosulfate sulfurtransferase activity
AM345_RS16060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM345_RS16065	COG0494	nUDIX hydrolase
AM345_RS16075	COG0604	alcohol dehydrogenase
AM345_RS16075	COG3321	synthase
AM345_RS16075	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS16085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM345_RS16090	COG0709	Synthesizes selenophosphate from selenide and ATP
AM345_RS16105	COG0778	Nitroreductase
AM345_RS16110	COG0616	signal peptide processing
AM345_RS16115	COG0252	asparaginase activity
AM345_RS16120	COG1335	isochorismatase
AM345_RS16130	COG3139	Protein of unknown function (DUF1315)
AM345_RS16150	COG3713	MltA-interacting MipA family protein
AM345_RS16155	COG2766	serine protein kinase
AM345_RS16170	COG2199	diguanylate cyclase activity
AM345_RS16175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM345_RS16185	COG2207	Transcriptional regulator
AM345_RS16190	COG2807	transmembrane transport
AM345_RS16195	COG0504	CTP synthase activity
AM345_RS16200	COG3189	MarR family transcriptional regulator
AM345_RS16205	COG3042	response to heat
AM345_RS16210	COG2199	diguanylate cyclase activity
AM345_RS16210	COG2203	Gaf domain
AM345_RS16230	COG3182	Iron-regulated membrane protein
AM345_RS16240	COG1560	Kdo2-lipid A biosynthetic process
AM345_RS16245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AM345_RS16250	COG3706	GGDEF domain
AM345_RS16315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM345_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS16430	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM345_RS16450	COG1760	l-serine dehydratase
AM345_RS16455	COG1882	Formate acetyltransferase
AM345_RS16460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM345_RS16475	COG0583	DNA-binding transcription factor activity
AM345_RS16480	COG2814	Major facilitator Superfamily
AM345_RS16495	COG4774	siderophore transport
AM345_RS16505	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM345_RS16525	COG2719	SpoVR family
AM345_RS16555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM345_RS16555	COG2755	lipolytic protein G-D-S-L family
AM345_RS16570	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM345_RS16585	COG2894	cell division
AM345_RS16595	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM345_RS16605	COG3065	identical protein binding
AM345_RS16615	COG1199	ATP-dependent helicase activity
AM345_RS16620	COG0251	oxidation-reduction process
AM345_RS16640	COG1760	l-serine dehydratase
AM345_RS16645	COG2200	EAL domain
AM345_RS16650	COG1253	flavin adenine dinucleotide binding
AM345_RS16655	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS16655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS16660	COG3715	PTS system
AM345_RS16665	COG3716	PTS system mannose fructose sorbose family IID component
AM345_RS16680	COG2226	methyltransferase
AM345_RS16685	COG0768	penicillin binding
AM345_RS16720	COG1414	Transcriptional regulator
AM345_RS16725	COG2814	Major facilitator Superfamily
AM345_RS16745	COG1956	GAF domain-containing protein
AM345_RS16750	COG2995	paraquat-inducible protein a
AM345_RS16755	COG3008	intermembrane lipid transfer
AM345_RS16780	COG2990	Protein conserved in bacteria
AM345_RS16820	COG1276	copper resistance
AM345_RS16825	COG2372	response to copper ion
AM345_RS16835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM345_RS16840	COG1770	oligopeptidase
AM345_RS16845	COG2979	Protein of unknown function (DUF533)
AM345_RS16850	COG3141	response to X-ray
AM345_RS16860	COG0800	Aldolase
AM345_RS16865	COG0129	dihydroxy-acid dehydratase activity
AM345_RS16870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM345_RS16880	COG1737	Transcriptional regulator
AM345_RS16890	COG1560	Kdo2-lipid A biosynthetic process
AM345_RS16895	COG0739	heme binding
AM345_RS16900	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM345_RS16910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM345_RS16935	COG0494	nUDIX hydrolase
AM345_RS16945	COG1335	isochorismatase
AM345_RS16950	COG1801	Protein of unknown function DUF72
AM345_RS16955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM345_RS16975	COG3102	Protein conserved in bacteria
AM345_RS16985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM345_RS17015	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM345_RS17025	COG1879	ABC-type sugar transport system periplasmic component
AM345_RS17030	COG1528	Iron-storage protein
AM345_RS17040	COG0477	Major facilitator Superfamily
AM345_RS17050	COG1528	Iron-storage protein
AM345_RS17060	COG0814	amino acid
AM345_RS17065	COG3318	Belongs to the UPF0149 family
AM345_RS17065	COG3012	SEC-C Motif Domain Protein
AM345_RS17070	COG3152	Membrane
AM345_RS17075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM345_RS17105	COG2197	response regulator
AM345_RS17115	COG2197	response regulator
AM345_RS17120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM345_RS17125	COG1126	abc transporter atp-binding protein
AM345_RS17130	COG0765	amino acid transport
AM345_RS17140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS17145	COG0366	Alpha amylase catalytic
AM345_RS17175	COG5475	Uncharacterized small protein (DUF2158)
AM345_RS17180	COG2354	Protein conserved in bacteria
AM345_RS17185	COG0697	spore germination
AM345_RS17190	COG3727	T/G mismatch-specific endonuclease activity
AM345_RS17195	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM345_RS17200	COG1418	mRNA catabolic process
AM345_RS17210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM345_RS17230	COG1376	ErfK ybiS ycfS ynhG family protein
AM345_RS17250	COG2977	Belongs to the P-Pant transferase superfamily
AM345_RS17270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM345_RS17280	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM345_RS17310	COG1725	Transcriptional regulator
AM345_RS17320	COG0534	Mate efflux family protein
AM345_RS17350	COG3615	Tellurite resistance protein tehB
AM345_RS17355	COG5001	Diguanylate cyclase
AM345_RS17355	COG3300	MHYT domain
AM345_RS17365	COG0477	Major facilitator Superfamily
AM345_RS17370	COG0095	Lipoate-protein ligase
AM345_RS17380	COG1082	Xylose isomerase domain protein TIM barrel
AM345_RS17385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS17385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS17390	COG0673	inositol 2-dehydrogenase activity
AM345_RS17395	COG2814	Major facilitator Superfamily
AM345_RS17405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM345_RS17430	COG1289	transmembrane transporter activity
AM345_RS17440	COG1686	Belongs to the peptidase S11 family
AM345_RS17445	COG2925	Exonuclease
AM345_RS17450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM345_RS17455	COG0640	Transcriptional regulator
AM345_RS17460	COG0531	amino acid
AM345_RS17470	COG0583	DNA-binding transcription factor activity
AM345_RS17475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM345_RS17490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM345_RS17505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM345_RS17530	COG0438	transferase activity, transferring glycosyl groups
AM345_RS17540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM345_RS17585	COG0438	transferase activity, transferring glycosyl groups
AM345_RS17620	COG2244	polysaccharide biosynthetic process
AM345_RS17625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM345_RS17665	COG1253	flavin adenine dinucleotide binding
AM345_RS17670	COG2982	Protein involved in outer membrane biogenesis
AM345_RS17685	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM345_RS17690	COG0443	Heat shock 70 kDa protein
AM345_RS17715	COG2205	protein histidine kinase activity
AM345_RS17720	COG0745	RESPONSE REGULATOR receiver
AM345_RS17725	COG0826	peptidase U32
AM345_RS17740	COG1070	Carbohydrate kinase
AM345_RS17750	COG2390	Transcriptional regulator
AM345_RS17775	COG1830	Aldolase
AM345_RS17780	COG0351	phosphomethylpyrimidine kinase
AM345_RS17805	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM345_RS17815	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM345_RS17825	COG0583	DNA-binding transcription factor activity
AM345_RS17835	COG2252	PERMEase
AM345_RS17840	COG0583	DNA-binding transcription factor activity
AM345_RS17845	COG5455	response to cobalt ion
AM345_RS17855	COG0489	protein tyrosine kinase activity
AM345_RS17870	COG4808	Protein conserved in bacteria
AM345_RS17875	COG4807	Protein conserved in bacteria
AM345_RS17885	COG3275	phosphorelay sensor kinase activity
AM345_RS17890	COG0789	Transcriptional regulator
AM345_RS17900	COG1174	glycine betaine transport
AM345_RS17905	COG1125	glycine betaine transport
AM345_RS17910	COG1174	glycine betaine transport
AM345_RS17915	COG1732	Glycine betaine
AM345_RS17920	COG1472	Belongs to the glycosyl hydrolase 3 family
AM345_RS17925	COG0277	FAD linked oxidase domain protein
AM345_RS17935	COG1686	Belongs to the peptidase S11 family
AM345_RS17945	COG0586	Pfam SNARE associated Golgi protein
AM345_RS17950	COG1538	Outer membrane efflux protein
AM345_RS17955	COG2226	methyltransferase
AM345_RS17960	COG2723	6-phospho-beta-galactosidase activity
AM345_RS17975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM345_RS17980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM345_RS17985	COG0625	glutathione transferase activity
AM345_RS18000	COG2271	Major facilitator Superfamily
AM345_RS18005	COG0583	DNA-binding transcription factor activity
AM345_RS18015	COG1346	cytolysis
AM345_RS18025	COG2949	membrane
AM345_RS18035	COG1129	ABC transporter
AM345_RS18055	COG2311	Membrane
AM345_RS18085	COG1393	Belongs to the ArsC family
AM345_RS18090	COG4771	TonB-dependent receptor
AM345_RS18095	COG0833	amino acid
AM345_RS18100	COG0583	DNA-binding transcription factor activity
AM345_RS18105	COG2855	membrane
AM345_RS18115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS18115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM345_RS18115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM345_RS18120	COG1105	Belongs to the carbohydrate kinase PfkB family
AM345_RS18150	COG1312	Catalyzes the dehydration of D-mannonate
AM345_RS18155	COG0246	Mannitol dehydrogenase
AM345_RS18160	COG0523	cobalamin synthesis protein
AM345_RS18165	COG0671	phosphoesterase, PA-phosphatase related
AM345_RS18170	COG0791	NLP P60 protein
AM345_RS18175	COG2200	EAL domain
AM345_RS18180	COG4166	transmembrane transport
AM345_RS18185	COG4174	ABC transporter (Permease)
AM345_RS18190	COG4239	(ABC) transporter, permease
AM345_RS18195	COG4172	Belongs to the ABC transporter superfamily
AM345_RS18210	COG2814	Major facilitator Superfamily
AM345_RS18215	COG1187	pseudouridine synthase activity
AM345_RS18220	COG1061	Type III restriction enzyme res subunit
AM345_RS18240	COG0494	nUDIX hydrolase
AM345_RS18245	COG1349	DNA-binding transcription factor activity
AM345_RS18270	COG0628	permease
AM345_RS18285	COG0659	secondary active sulfate transmembrane transporter activity
AM345_RS18290	COG2239	Acts as a magnesium transporter
AM345_RS18295	COG4615	Cyclic peptide transporter
AM345_RS18305	COG2169	Transcriptional regulator
AM345_RS18305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM345_RS18325	COG2198	Histidine kinase
AM345_RS18325	COG0642	Histidine kinase
AM345_RS18365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM345_RS18370	COG0584	glycerophosphoryl diester phosphodiesterase
AM345_RS18375	COG2271	Major facilitator Superfamily
AM345_RS18380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM345_RS18390	COG0247	lactate metabolic process
AM345_RS18415	COG0642	Histidine kinase
AM345_RS18440	COG0318	PFAM AMP-dependent synthetase and ligase
AM345_RS18465	COG1169	isochorismate synthase
AM345_RS18470	COG2153	protein acetylation
AM345_RS18485	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM345_RS18490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM345_RS18500	COG0839	Belongs to the complex I subunit 6 family
AM345_RS18555	COG0583	DNA-binding transcription factor activity
AM345_RS18560	COG0436	Aminotransferase
AM345_RS18570	COG0471	metal ion transport
AM345_RS18570	COG0490	domain, Protein
AM345_RS18575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM345_RS18605	COG0622	Phosphoesterase
AM345_RS18610	COG0625	glutathione transferase activity
AM345_RS18615	COG0625	glutathione transferase activity
AM345_RS18620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM345_RS18625	COG1090	epimerase
AM345_RS18645	COG4598	ABC transporter
AM345_RS18650	COG4160	amino acid transport
AM345_RS18665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM345_RS18675	COG0163	prenyltransferase activity
AM345_RS18680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM345_RS18685	COG1286	toxin biosynthetic process
AM345_RS18690	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM345_RS18695	COG0285	dihydrofolate synthase activity
AM345_RS18705	COG0586	Pfam SNARE associated Golgi protein
AM345_RS18715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM345_RS18730	COG2814	Major facilitator Superfamily
AM345_RS18735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM345_RS18750	COG3101	peptidyl-lysine hydroxylation
AM345_RS18755	COG0730	response to heat
AM345_RS18780	COG2062	phosphohistidine phosphatase, SixA
AM345_RS18795	COG3691	Protein conserved in bacteria
AM345_RS18805	COG2853	Lipoprotein
AM345_RS18810	COG2116	formate transmembrane transporter activity
AM345_RS18835	COG0590	tRNA wobble adenosine to inosine editing
AM345_RS18840	COG2807	transmembrane transport
AM345_RS18850	COG0436	Aminotransferase
AM345_RS18855	COG3275	phosphorelay sensor kinase activity
AM345_RS18860	COG3279	Response regulator of the LytR AlgR family
AM345_RS18875	COG3961	Belongs to the TPP enzyme family
AM345_RS18880	COG0667	Aldo Keto reductase
AM345_RS18895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM345_RS18900	COG2199	diguanylate cyclase activity
AM345_RS18900	COG2200	EAL domain
AM345_RS18915	COG3415	Transposase
AM345_RS18920	COG3415	Transposase
AM345_RS18960	COG0583	DNA-binding transcription factor activity
AM345_RS18965	COG0385	Bile acid
AM345_RS18970	COG3530	Putative quorum-sensing-regulated virulence factor
AM345_RS18995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS19035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM345_RS19040	COG4208	sulfate ABC transporter
AM345_RS19045	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM345_RS19050	COG4150	thiosulfate binding
AM345_RS19055	COG2837	iron assimilation
AM345_RS19075	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM345_RS19095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM345_RS19100	COG5342	invasion associated locus B
AM345_RS19110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS19110	COG0493	'glutamate synthase
AM345_RS19115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM345_RS19125	COG1393	Belongs to the ArsC family
AM345_RS19140	COG0400	carboxylic ester hydrolase activity
AM345_RS19150	COG2321	neutral zinc metallopeptidase
AM345_RS19160	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM345_RS19170	COG2716	regulation of RNA biosynthetic process
AM345_RS19175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM345_RS19180	COG0628	permease
AM345_RS19185	COG4783	chaperone-mediated protein folding
AM345_RS19190	COG1393	Belongs to the ArsC family
AM345_RS19205	COG2233	PERMEase
AM345_RS19215	COG2723	6-phospho-beta-galactosidase activity
AM345_RS19230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM345_RS19240	COG2211	Major facilitator Superfamily
AM345_RS19245	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM345_RS19260	COG0248	Ppx GppA phosphatase
AM345_RS19265	COG2200	EAL domain
AM345_RS19300	COG0516	GMP reductase activity
AM345_RS19300	COG0517	IMP dehydrogenase activity
AM345_RS19320	COG1645	bacterial-type flagellum-dependent swarming motility
AM345_RS19335	COG2976	Protein conserved in bacteria
AM345_RS19365	COG4953	penicillin-binding protein 1C
AM345_RS19370	COG2373	Large extracellular alpha-helical protein
AM345_RS19375	COG2897	thiosulfate sulfurtransferase activity
AM345_RS19390	COG2975	iron-sulfur cluster assembly
AM345_RS19395	COG0633	Ferredoxin
AM345_RS19415	COG0822	iron-sulfur transferase activity
AM345_RS19440	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM345_RS19445	COG3683	transport system, periplasmic component
AM345_RS19450	COG3711	transcriptional antiterminator
AM345_RS19455	COG2814	Major facilitator Superfamily
AM345_RS19460	COG2259	Doxx family
AM345_RS19470	COG1017	nitric oxide dioxygenase activity
AM345_RS19470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM345_RS19480	COG0347	Belongs to the P(II) protein family
AM345_RS19485	COG2204	response regulator
AM345_RS19490	COG3170	Tfp pilus assembly protein FimV
AM345_RS19495	COG2205	protein histidine kinase activity
AM345_RS19500	COG0047	phosphoribosylformylglycinamidine synthase activity
AM345_RS19500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM345_RS19520	COG0560	Phosphoserine phosphatase
AM345_RS19530	COG1737	Transcriptional regulator
AM345_RS19535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS19545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM345_RS19565	COG0681	Belongs to the peptidase S26 family
AM345_RS19575	COG3086	response to oxidative stress
AM345_RS19580	COG3026	antisigma factor binding
AM345_RS19585	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM345_RS19595	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM345_RS19605	COG0513	Belongs to the DEAD box helicase family
AM345_RS19620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM345_RS19625	COG3118	belongs to the thioredoxin family
AM345_RS19630	COG3148	PFAM DTW domain containing protein
AM345_RS19640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM345_RS19645	COG5544	Lipoprotein
AM345_RS19650	COG0477	Major facilitator Superfamily
AM345_RS19680	COG0542	response to heat
AM345_RS19695	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM345_RS19700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM345_RS19710	COG1605	Chorismate mutase
AM345_RS19710	COG0077	Prephenate dehydratase
AM345_RS19720	COG0287	Prephenate dehydrogenase
AM345_RS19720	COG1605	Chorismate mutase
AM345_RS19725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM345_RS19735	COG2199	diguanylate cyclase activity
AM345_RS19740	COG2885	chlorophyll binding
AM345_RS19775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM345_RS19780	COG4137	Cytochrome C assembly protein
AM345_RS19785	COG4536	flavin adenine dinucleotide binding
AM345_RS19800	COG0497	DNA recombination
AM345_RS19815	COG2867	negative regulation of translational initiation
AM345_RS19835	COG2135	peptidase activity
AM345_RS19840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM345_RS20005	COG3179	chitinase
AM345_RS20050	COG1403	HNH endonuclease
AM345_RS20060	COG4725	Belongs to the MT-A70-like family
AM345_RS20065	COG4626	Terminase
AM345_RS20065	COG1802	Transcriptional regulator
AM345_RS20095	COG1396	sequence-specific DNA binding
AM345_RS20110	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM345_RS20160	COG0582	viral genome integration into host DNA
AM345_RS20165	COG0582	viral genome integration into host DNA
AM345_RS20175	COG5290	Psort location Cytoplasmic, score
AM345_RS20215	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM345_RS20225	COG2169	Transcriptional regulator
AM345_RS20230	COG3813	Protein conserved in bacteria
AM345_RS20240	COG0243	molybdopterin cofactor binding
AM345_RS20245	COG3005	denitrification pathway
AM345_RS20250	COG3088	subunit of a heme lyase
AM345_RS20250	COG4235	cytochrome complex assembly
AM345_RS20255	COG4235	cytochrome complex assembly
AM345_RS20255	COG3088	subunit of a heme lyase
AM345_RS20260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM345_RS20265	COG1138	Cytochrome C-type biogenesis protein
AM345_RS20275	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM345_RS20280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM345_RS20285	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM345_RS20290	COG4133	protoheme IX ABC transporter activity
AM345_RS20295	COG0477	Major facilitator Superfamily
AM345_RS20300	COG0583	DNA-binding transcription factor activity
AM345_RS20305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM345_RS20310	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS20340	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM345_RS20345	COG0747	negative chemotaxis
AM345_RS20350	COG0601	transmembrane transport
AM345_RS20355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM345_RS20360	COG0444	Belongs to the ABC transporter superfamily
AM345_RS20365	COG4608	Belongs to the ABC transporter superfamily
AM345_RS20380	COG3284	Transcriptional regulator
AM345_RS20385	COG0671	phosphoesterase, PA-phosphatase related
AM345_RS20390	COG0583	DNA-binding transcription factor activity
AM345_RS20400	COG0640	Transcriptional regulator
AM345_RS20405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM345_RS20440	COG4575	ribosome binding
AM345_RS20450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM345_RS20455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM345_RS20465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM345_RS20470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM345_RS20480	COG4176	ABC-type proline glycine betaine transport system permease component
AM345_RS20490	COG1846	Transcriptional regulator
AM345_RS20495	COG1566	PFAM secretion protein HlyD family protein
AM345_RS20500	COG2814	Major facilitator Superfamily
AM345_RS20505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM345_RS20525	COG1238	metal cluster binding
AM345_RS20530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM345_RS20535	COG2823	Periplasmic or secreted lipoprotein
AM345_RS20565	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM345_RS20590	COG1546	Belongs to the CinA family
AM345_RS20595	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM345_RS20600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM345_RS20615	COG2951	lytic endotransglycosylase activity
AM345_RS20620	COG3730	PTS system glucitol sorbitol-specific
AM345_RS20625	COG3732	PTS system glucitol sorbitol-specific
AM345_RS20635	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS20640	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS20645	COG1349	DNA-binding transcription factor activity
AM345_RS20670	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AM345_RS20675	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM345_RS20680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS20685	COG1609	Transcriptional regulator
AM345_RS20690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS20690	COG1263	PTS System
AM345_RS20695	COG2723	6-phospho-beta-galactosidase activity
AM345_RS20705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM345_RS20715	COG3260	NADH ubiquinone oxidoreductase 20
AM345_RS20720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM345_RS20725	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM345_RS20725	COG3261	NADH dehydrogenase
AM345_RS20730	COG0650	Formate hydrogenlyase subunit 4
AM345_RS20735	COG0651	ATP synthesis coupled electron transport
AM345_RS20740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS20755	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM345_RS20760	COG0298	carbon dioxide binding
AM345_RS20765	COG0409	Hydrogenase expression formation protein
AM345_RS20770	COG0309	Hydrogenase expression formation protein (HypE)
AM345_RS20785	COG1121	(ABC) transporter
AM345_RS20790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM345_RS20795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM345_RS20810	COG0583	DNA-binding transcription factor activity
AM345_RS20815	COG0679	Auxin Efflux Carrier
AM345_RS20835	COG3720	iron ion transport
AM345_RS20840	COG4558	Periplasmic binding protein
AM345_RS20845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM345_RS20880	COG3121	Chaperone
AM345_RS20895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM345_RS20900	COG0163	prenyltransferase activity
AM345_RS20920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM345_RS20925	COG4942	peptidase
AM345_RS20925	COG1388	LysM domain
AM345_RS20955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM345_RS20985	COG2234	aminopeptidase activity
AM345_RS21010	COG0720	synthase
AM345_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS21020	COG0602	queuosine metabolic process
AM345_RS21040	COG3956	TIGRFAM MazG family protein
AM345_RS21045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM345_RS21055	COG3437	response regulator, receiver
AM345_RS21055	COG4999	Histidine kinase
AM345_RS21055	COG2205	protein histidine kinase activity
AM345_RS21055	COG3850	Histidine kinase
AM345_RS21060	COG1929	Belongs to the glycerate kinase type-1 family
AM345_RS21065	COG4948	Mandelate Racemase Muconate Lactonizing
AM345_RS21070	COG4948	Mandelate Racemase Muconate Lactonizing
AM345_RS21075	COG2271	Major facilitator Superfamily
AM345_RS21085	COG0716	FMN binding
AM345_RS21090	COG0564	pseudouridine synthase activity
AM345_RS21095	COG3098	single-species biofilm formation
AM345_RS21110	COG1611	Belongs to the LOG family
AM345_RS21115	COG0814	amino acid
AM345_RS21120	COG1760	l-serine dehydratase
AM345_RS21135	COG2363	Small membrane protein
AM345_RS21140	COG0583	DNA-binding transcription factor activity
AM345_RS21145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM345_RS21150	COG2166	iron-sulfur cluster assembly
AM345_RS21155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM345_RS21160	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM345_RS21180	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM345_RS21185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM345_RS21185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM345_RS21190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM345_RS21195	COG1074	ATP-dependent DNA helicase activity
AM345_RS21200	COG1025	Belongs to the peptidase M16 family
AM345_RS21205	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM345_RS21220	COG4795	General secretion pathway protein
AM345_RS21225	COG2165	general secretion pathway protein
AM345_RS21265	COG0861	Integral membrane protein TerC family
AM345_RS21275	COG0667	Aldo Keto reductase
AM345_RS21300	COG1609	Transcriptional regulator
AM345_RS21310	COG1609	Transcriptional regulator
AM345_RS21320	COG0583	DNA-binding transcription factor activity
AM345_RS21325	COG1794	racemase activity, acting on amino acids and derivatives
AM345_RS21350	COG2814	Major facilitator Superfamily
AM345_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS21360	COG0183	Belongs to the thiolase family
AM345_RS21365	COG0583	DNA-binding transcription factor activity
AM345_RS21375	COG0814	amino acid
AM345_RS21380	COG0667	Aldo Keto reductase
AM345_RS21395	COG0640	Transcriptional regulator
AM345_RS21410	COG0697	spore germination
AM345_RS21415	COG1846	Transcriptional regulator
AM345_RS21425	COG0154	amidase activity
AM345_RS21430	COG1960	acyl-CoA dehydrogenase activity
AM345_RS21440	COG4638	Rieske (2fe-2S)
AM345_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS21460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM345_RS21475	COG3188	usher protein
AM345_RS21480	COG3121	Chaperone
AM345_RS21485	COG3539	Fimbrial protein
AM345_RS21510	COG0582	viral genome integration into host DNA
AM345_RS21515	COG4974	Belongs to the 'phage' integrase family
AM345_RS21530	COG3539	Fimbrial protein
AM345_RS21535	COG3121	Chaperone
AM345_RS21540	COG3188	usher protein
AM345_RS21545	COG3539	Fimbrial protein
AM345_RS21550	COG3539	Fimbrial protein
AM345_RS21555	COG3539	Fimbrial protein
AM345_RS21565	COG2388	GCN5-related N-acetyl-transferase
AM345_RS21570	COG3592	Divergent 4Fe-4S mono-cluster
AM345_RS21585	COG1289	transmembrane transporter activity
AM345_RS21590	COG1538	Outer membrane efflux protein
AM345_RS21600	COG1982	Orn Lys Arg decarboxylase major
AM345_RS21605	COG0531	amino acid
AM345_RS21620	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM345_RS21645	COG2271	Major facilitator Superfamily
AM345_RS21650	COG0483	inositol monophosphate 1-phosphatase activity
AM345_RS21655	COG1609	Transcriptional regulator
AM345_RS21660	COG0753	catalase activity
AM345_RS21670	COG0531	amino acid
AM345_RS21680	COG0124	histidyl-tRNA synthetase
AM345_RS21685	COG0124	histidyl-tRNA synthetase
AM345_RS21700	COG3539	Fimbrial protein
AM345_RS21710	COG3121	Chaperone
AM345_RS21715	COG3188	usher protein
AM345_RS21725	COG3539	Fimbrial protein
AM345_RS21755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM345_RS21765	COG4942	peptidase
AM345_RS21785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM345_RS21795	COG4974	Belongs to the 'phage' integrase family
AM345_RS21800	COG0716	FMN binding
AM345_RS21810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM345_RS21820	COG1272	protein, Hemolysin III
AM345_RS21830	COG1737	Transcriptional regulator
AM345_RS21835	COG2723	6-phospho-beta-galactosidase activity
AM345_RS21855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM345_RS21860	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS21880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM345_RS21885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM345_RS21890	COG0006	proline dipeptidase activity
AM345_RS21910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM345_RS21915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM345_RS21930	COG2968	Membrane
AM345_RS21935	COG1279	arginine transmembrane transporter activity
AM345_RS21940	COG0668	transmembrane transport
AM345_RS21945	COG0191	fructose-bisphosphate aldolase activity
AM345_RS21960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM345_RS21965	COG0501	Belongs to the peptidase M48B family
AM345_RS21985	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM345_RS21990	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS22020	COG1414	Transcriptional regulator
AM345_RS22025	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS22040	COG2146	nitrite reductase [NAD(P)H] activity
AM345_RS22085	COG2814	Major facilitator Superfamily
AM345_RS22095	COG2356	endonuclease I
AM345_RS22100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM345_RS22105	COG0189	ligase activity
AM345_RS22120	COG2197	response regulator
AM345_RS22125	COG2805	Type II/IV secretion system protein
AM345_RS22130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM345_RS22135	COG0762	integral membrane protein
AM345_RS22150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM345_RS22165	COG4214	carbohydrate transport
AM345_RS22175	COG3171	Protein conserved in bacteria
AM345_RS22185	COG1194	a g-specific adenine glycosylase
AM345_RS22200	COG2211	Major facilitator Superfamily
AM345_RS22210	COG1982	Orn Lys Arg decarboxylase major
AM345_RS22220	COG1811	Na channel or pump
AM345_RS22255	COG2731	YhcH YjgK YiaL family protein
AM345_RS22280	COG2186	Transcriptional regulator
AM345_RS22300	COG2382	esterase
AM345_RS22310	COG4771	TonB-dependent receptor
AM345_RS22320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM345_RS22335	COG4977	sequence-specific DNA binding
AM345_RS22335	COG1917	Cupin 2, conserved barrel domain protein
AM345_RS22340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM345_RS22345	COG3753	Protein conserved in bacteria
AM345_RS22350	COG1652	LysM domain
AM345_RS22355	COG0583	DNA-binding transcription factor activity
AM345_RS22365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM345_RS22370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM345_RS22385	COG2072	flavoprotein involved in K transport
AM345_RS22395	COG0583	DNA-binding transcription factor activity
AM345_RS22405	COG1012	belongs to the aldehyde dehydrogenase family
AM345_RS22425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM345_RS22430	COG0754	glutathionylspermidine amidase activity
AM345_RS22440	COG0625	glutathione transferase activity
AM345_RS22450	COG0848	biopolymer transport protein
AM345_RS22465	COG0626	cystathionine gamma-synthase activity
AM345_RS22470	COG0586	Pfam SNARE associated Golgi protein
AM345_RS22475	COG2207	Transcriptional regulator
AM345_RS22485	COG1979	alcohol dehydrogenase
AM345_RS22490	COG0656	L-ascorbic acid biosynthetic process
AM345_RS22500	COG1032	radical SAM domain protein
AM345_RS22510	COG0204	Acyl-transferase
AM345_RS22520	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM345_RS22525	COG3111	PFAM Bacterial OB fold (BOF) protein
AM345_RS22535	COG0642	Histidine kinase
AM345_RS22540	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM345_RS22545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM345_RS22550	COG0187	DNA topoisomerase II activity
AM345_RS22555	COG3150	esterase
AM345_RS22560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM345_RS22565	COG3151	Protein conserved in bacteria
AM345_RS22570	COG0494	nUDIX hydrolase
AM345_RS22585	COG0754	glutathionylspermidine amidase activity
AM345_RS22590	COG3384	dioxygenase
AM345_RS22600	COG2960	long-chain fatty acid transporting porin activity
AM345_RS22620	COG3025	triphosphatase activity
AM345_RS22625	COG4991	sh3 domain protein
AM345_RS22640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM345_RS22650	COG0477	Major facilitator Superfamily
AM345_RS22660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM345_RS22665	COG0358	DNA primase activity
AM345_RS22675	COG3663	DNA glycosylase
AM345_RS22715	COG3119	arylsulfatase activity
AM345_RS22720	COG0641	radical SAM
AM345_RS22725	COG0714	Associated with various cellular activities
AM345_RS22760	COG0641	radical SAM
AM345_RS22785	COG2376	Dihydroxyacetone kinase
AM345_RS22790	COG1461	Dihydroxyacetone kinase
AM345_RS22805	COG2375	cellular response to nickel ion
AM345_RS22810	COG1695	Transcriptional regulator
AM345_RS22820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM345_RS22825	COG1609	Transcriptional regulator
AM345_RS22830	COG3250	beta-galactosidase activity
AM345_RS22835	COG2731	YhcH YjgK YiaL family protein
AM345_RS22840	COG0531	amino acid
AM345_RS22845	COG0531	amino acid
AM345_RS22855	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM345_RS22855	COG3408	Glycogen debranching enzyme
AM345_RS22900	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM345_RS22900	COG1902	pentaerythritol trinitrate reductase activity
AM345_RS22910	COG1451	nucleotide metabolic process
AM345_RS22915	COG0673	inositol 2-dehydrogenase activity
AM345_RS22920	COG0861	Integral membrane protein TerC family
AM345_RS22935	COG2721	sulfolactate sulfo-lyase activity
AM345_RS22945	COG2271	Major facilitator Superfamily
AM345_RS22950	COG2186	Transcriptional regulator
AM345_RS22955	COG0586	Pfam SNARE associated Golgi protein
AM345_RS22965	COG1422	Protein of unknown function (DUF1090)
AM345_RS22970	COG4575	ribosome binding
AM345_RS22975	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM345_RS22990	COG2259	Doxx family
AM345_RS22995	COG0435	Glutathione S-transferase
AM345_RS23000	COG3152	Membrane
AM345_RS23005	COG0583	DNA-binding transcription factor activity
AM345_RS23010	COG1741	Belongs to the pirin family
AM345_RS23025	COG0668	transmembrane transport
AM345_RS23040	COG1929	Belongs to the glycerate kinase type-1 family
AM345_RS23045	COG2084	Dehydrogenase
AM345_RS23055	COG2721	sulfolactate sulfo-lyase activity
AM345_RS23060	COG1349	DNA-binding transcription factor activity
AM345_RS23070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM345_RS23080	COG3716	PTS system mannose fructose sorbose family IID component
AM345_RS23085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS23090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM345_RS23095	COG2222	sugar isomerase
AM345_RS23110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM345_RS23130	COG2823	Periplasmic or secreted lipoprotein
AM345_RS23140	COG0701	Predicted permease
AM345_RS23145	COG0702	epimerase
AM345_RS23150	COG0693	protein deglycase activity
AM345_RS23165	COG3153	acetyltransferase
AM345_RS23170	COG3154	lipid carrier protein
AM345_RS23175	COG0826	peptidase U32
AM345_RS23180	COG0826	peptidase U32
AM345_RS23185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM345_RS23190	COG0814	amino acid
AM345_RS23240	COG0195	Participates in both transcription termination and antitermination
AM345_RS23280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM345_RS23290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM345_RS23295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM345_RS23305	COG1534	Rna-binding protein
AM345_RS23315	COG2027	D-alanyl-D-alanine carboxypeptidase
AM345_RS23325	COG0697	spore germination
AM345_RS23340	COG0142	geranyltranstransferase activity
AM345_RS23345	COG3423	Transcriptional regulator
AM345_RS23355	COG5007	Belongs to the BolA IbaG family
AM345_RS23360	COG3113	response to antibiotic
AM345_RS23365	COG2854	intermembrane phospholipid transfer
AM345_RS23370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM345_RS23375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM345_RS23380	COG1127	ABC transporter
AM345_RS23390	COG0530	calcium, potassium:sodium antiporter activity
AM345_RS23400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM345_RS23405	COG3117	lipopolysaccharide transmembrane transporter activity
AM345_RS23410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM345_RS23415	COG1137	ATPase activity
AM345_RS23420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM345_RS23425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM345_RS23430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS23440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM345_RS23445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM345_RS23450	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM345_RS23455	COG5002	protein histidine kinase activity
AM345_RS23455	COG0784	Response regulator, receiver
AM345_RS23455	COG2198	Histidine kinase
AM345_RS23460	COG1242	4 iron, 4 sulfur cluster binding
AM345_RS23470	COG0067	glutamate synthase
AM345_RS23470	COG0069	glutamate synthase activity
AM345_RS23470	COG0070	glutamate synthase
AM345_RS23475	COG0493	'glutamate synthase
AM345_RS23480	COG2969	positive regulation of protein catabolic process
AM345_RS23485	COG0625	glutathione transferase activity
AM345_RS23505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM345_RS23510	COG3105	Protein conserved in bacteria
AM345_RS23515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM345_RS23520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM345_RS23555	COG2732	(Barnase) inhibitor
AM345_RS23560	COG1289	transmembrane transporter activity
AM345_RS23575	COG0583	DNA-binding transcription factor activity
AM345_RS23580	COG0312	modulator of DNA gyrase
AM345_RS23585	COG3164	Protein of unknown function
AM345_RS23600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM345_RS23605	COG1792	Involved in formation and maintenance of cell shape
AM345_RS23610	COG1077	Cell shape determining protein MreB Mrl
AM345_RS23620	COG2200	EAL domain
AM345_RS23620	COG2199	diguanylate cyclase activity
AM345_RS23625	COG0604	alcohol dehydrogenase
AM345_RS23640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM345_RS23650	COG0511	ligase activity, forming carbon-carbon bonds
AM345_RS23655	COG0439	Biotin carboxylase
AM345_RS23660	COG3924	membrane
AM345_RS23665	COG4145	pantothenate transmembrane transporter activity
AM345_RS23685	COG1309	transcriptional regulator
AM345_RS23690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM345_RS23695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM345_RS23735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM345_RS23755	COG0551	DNA topoisomerase type I activity
AM345_RS23765	COG0758	DNA mediated transformation
AM345_RS23795	COG3036	rescue of stalled ribosome
AM345_RS23800	COG0789	Transcriptional regulator
AM345_RS23825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM345_RS23840	COG0201	protein transport
AM345_RS23905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM345_RS23920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM345_RS23945	COG0051	transcription antitermination factor activity, RNA binding
AM345_RS24000	COG2964	Protein conserved in bacteria
AM345_RS24010	COG0545	Peptidyl-prolyl cis-trans isomerase
AM345_RS24020	COG1047	Peptidyl-prolyl cis-trans
AM345_RS24025	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM345_RS24040	COG0488	(ABC) transporter
AM345_RS24050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM345_RS24060	COG0429	hydrolase of the alpha beta-hydrolase fold
AM345_RS24070	COG3954	Phosphoribulokinase
AM345_RS24075	COG1765	OsmC-like protein
AM345_RS24085	COG1289	transmembrane transporter activity
AM345_RS24090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM345_RS24100	COG2184	nucleotidyltransferase activity
AM345_RS24115	COG0738	Major facilitator superfamily
AM345_RS24120	COG0402	S-adenosylhomocysteine deaminase activity
AM345_RS24125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM345_RS24130	COG2146	nitrite reductase [NAD(P)H] activity
AM345_RS24150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM345_RS24155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM345_RS24160	COG3266	domain, Protein
AM345_RS24180	COG4796	Type ii and iii secretion system protein
AM345_RS24205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM345_RS24215	COG0494	nUDIX hydrolase
AM345_RS24225	COG1011	Hydrolase
AM345_RS24230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM345_RS24255	COG0738	Major facilitator superfamily
AM345_RS24260	COG3254	rhamnose metabolic process
AM345_RS24275	COG4948	Mandelate Racemase Muconate Lactonizing
AM345_RS24280	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM345_RS24285	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS24295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM345_RS24300	COG2183	response to ionizing radiation
AM345_RS24305	COG1918	ferrous iron import across plasma membrane
AM345_RS24330	COG1040	competence protein
AM345_RS24340	COG2610	gluconate transmembrane transporter activity
AM345_RS24345	COG1640	4-alpha-glucanotransferase
AM345_RS24350	COG0058	SHG alpha-glucan phosphorylase activity
AM345_RS24360	COG1349	DNA-binding transcription factor activity
AM345_RS24375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM345_RS24380	COG0058	SHG alpha-glucan phosphorylase activity
AM345_RS24405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM345_RS24415	COG2610	gluconate transmembrane transporter activity
AM345_RS24420	COG3265	gluconokinase activity
AM345_RS24425	COG1609	Transcriptional regulator
AM345_RS24430	COG1741	Belongs to the pirin family
AM345_RS24435	COG0673	inositol 2-dehydrogenase activity
AM345_RS24445	COG1247	-acetyltransferase
AM345_RS24450	COG0405	Gamma-glutamyltransferase
AM345_RS24460	COG0584	glycerophosphoryl diester phosphodiesterase
AM345_RS24500	COG0411	ABC transporter
AM345_RS24510	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM345_RS24515	COG0683	leucine binding
AM345_RS24530	COG0683	leucine binding
AM345_RS24540	COG2177	Part of the ABC transporter FtsEX involved in
AM345_RS24545	COG2884	Cell division ATP-binding protein ftsE
AM345_RS24550	COG0552	protein localization to endoplasmic reticulum
AM345_RS24555	COG0742	ribosomal rna small subunit methyltransferase
AM345_RS24560	COG3776	membrane
AM345_RS24570	COG3714	YhhN family
AM345_RS24585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM345_RS24595	COG0477	Major facilitator Superfamily
AM345_RS24615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM345_RS24625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM345_RS24625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM345_RS24660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM345_RS24670	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS24675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM345_RS24680	COG2091	lysine biosynthetic process via aminoadipic acid
AM345_RS24720	COG3479	Phenolic acid decarboxylase
AM345_RS24730	COG0747	negative chemotaxis
AM345_RS24735	COG0601	transmembrane transport
AM345_RS24740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM345_RS24770	COG2239	Acts as a magnesium transporter
AM345_RS24775	COG2081	HI0933 family
AM345_RS24780	COG0306	phosphate transporter
AM345_RS24790	COG0589	response to stress
AM345_RS24810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM345_RS24815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM345_RS24825	COG2610	gluconate transmembrane transporter activity
AM345_RS24830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM345_RS24835	COG1609	Transcriptional regulator
AM345_RS24840	COG0625	glutathione transferase activity
AM345_RS24845	COG1454	alcohol dehydrogenase
AM345_RS24855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM345_RS24865	COG2197	response regulator
AM345_RS24870	COG1028	Short-chain dehydrogenase reductase Sdr
AM345_RS24875	COG0583	DNA-binding transcription factor activity
AM345_RS24880	COG1295	ribonuclease BN
AM345_RS24885	COG0477	Major facilitator Superfamily
AM345_RS24890	COG2982	Protein involved in outer membrane biogenesis
AM345_RS24905	COG0612	Peptidase, M16
AM345_RS24915	COG2200	EAL domain
AM345_RS24915	COG2199	diguanylate cyclase activity
AM345_RS24920	COG0457	Tetratricopeptide repeat
AM345_RS24920	COG3118	belongs to the thioredoxin family
AM345_RS24925	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM345_RS24930	COG1215	transferase activity, transferring glycosyl groups
AM345_RS24960	COG2194	sulfuric ester hydrolase activity
AM345_RS24985	COG4608	Belongs to the ABC transporter superfamily
AM345_RS24990	COG0444	Belongs to the ABC transporter superfamily
AM345_RS24995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM345_RS25000	COG0601	transmembrane transport
AM345_RS25005	COG0747	negative chemotaxis
AM345_RS25025	COG2223	nitrite transmembrane transporter activity
AM345_RS25035	COG5571	outer membrane autotransporter
AM345_RS25040	COG2818	Glycosylase
AM345_RS25045	COG0456	acetyltransferase
AM345_RS25050	COG0243	molybdopterin cofactor binding
AM345_RS25055	COG2885	chlorophyll binding
AM345_RS25060	COG1609	Transcriptional regulator
AM345_RS25070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM345_RS25090	COG2814	Major facilitator Superfamily
AM345_RS25095	COG2944	sequence-specific DNA binding
AM345_RS25100	COG1278	Cold shock
AM345_RS25125	COG3274	enterobacterial common antigen metabolic process
AM345_RS25130	COG4682	membrane
AM345_RS25135	COG1070	Carbohydrate kinase
AM345_RS25150	COG4213	ABC transporter substrate-binding protein
AM345_RS25160	COG4214	carbohydrate transport
AM345_RS25165	COG2207	Transcriptional regulator
AM345_RS25165	COG1609	Transcriptional regulator
AM345_RS25170	COG2992	FlgJ-related protein
AM345_RS25180	COG0366	Alpha amylase catalytic
AM345_RS25185	COG3977	Valine--pyruvate aminotransferase
AM345_RS25190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM345_RS25195	COG1454	alcohol dehydrogenase
AM345_RS25200	COG3276	selenocysteine insertion sequence binding