locus-tag	class	description
F8267_RS00010	COG1276	copper resistance
F8267_RS00015	COG2372	response to copper ion
F8267_RS00025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F8267_RS00030	COG1770	oligopeptidase
F8267_RS00035	COG2979	Protein of unknown function (DUF533)
F8267_RS00040	COG3141	response to X-ray
F8267_RS00050	COG0800	Aldolase
F8267_RS00055	COG0129	dihydroxy-acid dehydratase activity
F8267_RS00060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F8267_RS00065	COG1737	Transcriptional regulator
F8267_RS00075	COG1560	Kdo2-lipid A biosynthetic process
F8267_RS00080	COG0739	heme binding
F8267_RS00085	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F8267_RS00095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F8267_RS00120	COG0494	nUDIX hydrolase
F8267_RS00130	COG1335	isochorismatase
F8267_RS00135	COG1801	Protein of unknown function DUF72
F8267_RS00140	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F8267_RS00160	COG3102	Protein conserved in bacteria
F8267_RS00170	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F8267_RS00195	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS00205	COG1879	ABC-type sugar transport system periplasmic component
F8267_RS00210	COG1528	Iron-storage protein
F8267_RS00220	COG0477	Major facilitator Superfamily
F8267_RS00230	COG1528	Iron-storage protein
F8267_RS00240	COG0814	amino acid
F8267_RS00245	COG3012	SEC-C Motif Domain Protein
F8267_RS00245	COG3318	Belongs to the UPF0149 family
F8267_RS00250	COG3152	Membrane
F8267_RS00255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F8267_RS00285	COG2197	response regulator
F8267_RS00295	COG2197	response regulator
F8267_RS00300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F8267_RS00325	COG0366	Alpha amylase catalytic
F8267_RS00355	COG5475	Uncharacterized small protein (DUF2158)
F8267_RS00360	COG2354	Protein conserved in bacteria
F8267_RS00365	COG0697	spore germination
F8267_RS00370	COG3727	T/G mismatch-specific endonuclease activity
F8267_RS00375	COG0270	DNA (cytosine-5-)-methyltransferase activity
F8267_RS00380	COG1418	mRNA catabolic process
F8267_RS00390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F8267_RS00410	COG1376	ErfK ybiS ycfS ynhG family protein
F8267_RS00430	COG2977	Belongs to the P-Pant transferase superfamily
F8267_RS00450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F8267_RS00460	COG1181	Belongs to the D-alanine--D-alanine ligase family
F8267_RS00490	COG1725	Transcriptional regulator
F8267_RS00500	COG0534	Mate efflux family protein
F8267_RS00530	COG3615	Tellurite resistance protein tehB
F8267_RS00535	COG5001	Diguanylate cyclase
F8267_RS00535	COG3300	MHYT domain
F8267_RS00545	COG0477	Major facilitator Superfamily
F8267_RS00550	COG0095	Lipoate-protein ligase
F8267_RS00560	COG1082	Xylose isomerase domain protein TIM barrel
F8267_RS00565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS00565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS00570	COG0673	inositol 2-dehydrogenase activity
F8267_RS00575	COG2814	Major facilitator Superfamily
F8267_RS00585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F8267_RS00610	COG1289	transmembrane transporter activity
F8267_RS00620	COG1686	Belongs to the peptidase S11 family
F8267_RS00625	COG2925	Exonuclease
F8267_RS00630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F8267_RS00635	COG0640	Transcriptional regulator
F8267_RS00640	COG0531	amino acid
F8267_RS00650	COG0583	DNA-binding transcription factor activity
F8267_RS00655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F8267_RS00670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F8267_RS00685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F8267_RS00710	COG0438	transferase activity, transferring glycosyl groups
F8267_RS00720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F8267_RS00765	COG0438	transferase activity, transferring glycosyl groups
F8267_RS00800	COG2244	polysaccharide biosynthetic process
F8267_RS00805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F8267_RS00850	COG1253	flavin adenine dinucleotide binding
F8267_RS00855	COG2982	Protein involved in outer membrane biogenesis
F8267_RS00870	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F8267_RS00875	COG0443	Heat shock 70 kDa protein
F8267_RS00905	COG2205	protein histidine kinase activity
F8267_RS00910	COG0745	RESPONSE REGULATOR receiver
F8267_RS00930	COG1070	Carbohydrate kinase
F8267_RS00940	COG2390	Transcriptional regulator
F8267_RS00965	COG1830	Aldolase
F8267_RS00970	COG0351	phosphomethylpyrimidine kinase
F8267_RS00990	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F8267_RS01000	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F8267_RS01010	COG0583	DNA-binding transcription factor activity
F8267_RS01020	COG2252	PERMEase
F8267_RS01025	COG0583	DNA-binding transcription factor activity
F8267_RS01030	COG5455	response to cobalt ion
F8267_RS01040	COG0489	protein tyrosine kinase activity
F8267_RS01050	COG4808	Protein conserved in bacteria
F8267_RS01055	COG4807	Protein conserved in bacteria
F8267_RS01065	COG3275	phosphorelay sensor kinase activity
F8267_RS01070	COG0789	Transcriptional regulator
F8267_RS01080	COG1174	glycine betaine transport
F8267_RS01085	COG1125	glycine betaine transport
F8267_RS01090	COG1174	glycine betaine transport
F8267_RS01095	COG1732	Glycine betaine
F8267_RS01100	COG1472	Belongs to the glycosyl hydrolase 3 family
F8267_RS01105	COG0277	FAD linked oxidase domain protein
F8267_RS01115	COG1686	Belongs to the peptidase S11 family
F8267_RS01125	COG0586	Pfam SNARE associated Golgi protein
F8267_RS01130	COG1538	Outer membrane efflux protein
F8267_RS01135	COG2226	methyltransferase
F8267_RS01140	COG2723	6-phospho-beta-galactosidase activity
F8267_RS01155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F8267_RS01160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F8267_RS01165	COG0625	glutathione transferase activity
F8267_RS01180	COG2271	Major facilitator Superfamily
F8267_RS01185	COG0583	DNA-binding transcription factor activity
F8267_RS01195	COG1346	cytolysis
F8267_RS01205	COG2949	membrane
F8267_RS01215	COG1129	ABC transporter
F8267_RS01230	COG2311	Membrane
F8267_RS01255	COG1393	Belongs to the ArsC family
F8267_RS01260	COG4771	TonB-dependent receptor
F8267_RS01265	COG0833	amino acid
F8267_RS01270	COG0583	DNA-binding transcription factor activity
F8267_RS01275	COG2855	membrane
F8267_RS01285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS01285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS01285	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F8267_RS01290	COG1105	Belongs to the carbohydrate kinase PfkB family
F8267_RS01315	COG1312	Catalyzes the dehydration of D-mannonate
F8267_RS01320	COG0246	Mannitol dehydrogenase
F8267_RS01325	COG0523	cobalamin synthesis protein
F8267_RS01330	COG0671	phosphoesterase, PA-phosphatase related
F8267_RS01335	COG0791	NLP P60 protein
F8267_RS01340	COG2200	EAL domain
F8267_RS01345	COG4166	transmembrane transport
F8267_RS01350	COG4174	ABC transporter (Permease)
F8267_RS01355	COG4239	(ABC) transporter, permease
F8267_RS01360	COG4172	Belongs to the ABC transporter superfamily
F8267_RS01370	COG2814	Major facilitator Superfamily
F8267_RS01375	COG1187	pseudouridine synthase activity
F8267_RS01380	COG1061	Type III restriction enzyme res subunit
F8267_RS01400	COG0494	nUDIX hydrolase
F8267_RS01405	COG1349	DNA-binding transcription factor activity
F8267_RS01430	COG0628	permease
F8267_RS01445	COG0659	secondary active sulfate transmembrane transporter activity
F8267_RS01450	COG2239	Acts as a magnesium transporter
F8267_RS01455	COG4615	Cyclic peptide transporter
F8267_RS01465	COG2169	Transcriptional regulator
F8267_RS01465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F8267_RS01480	COG0642	Histidine kinase
F8267_RS01480	COG2198	Histidine kinase
F8267_RS01515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F8267_RS01525	COG2271	Major facilitator Superfamily
F8267_RS01530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F8267_RS01540	COG0247	lactate metabolic process
F8267_RS01560	COG0642	Histidine kinase
F8267_RS01585	COG0318	PFAM AMP-dependent synthetase and ligase
F8267_RS01610	COG1169	isochorismate synthase
F8267_RS01615	COG2153	protein acetylation
F8267_RS01630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F8267_RS01635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F8267_RS01645	COG0839	Belongs to the complex I subunit 6 family
F8267_RS01695	COG0583	DNA-binding transcription factor activity
F8267_RS01700	COG0436	Aminotransferase
F8267_RS01710	COG0490	domain, Protein
F8267_RS01710	COG0471	metal ion transport
F8267_RS01715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F8267_RS01745	COG0622	Phosphoesterase
F8267_RS01750	COG0625	glutathione transferase activity
F8267_RS01755	COG0625	glutathione transferase activity
F8267_RS01760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F8267_RS01765	COG1090	epimerase
F8267_RS01785	COG4598	ABC transporter
F8267_RS01790	COG4160	amino acid transport
F8267_RS01805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS01815	COG0163	prenyltransferase activity
F8267_RS01820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F8267_RS01825	COG1286	toxin biosynthetic process
F8267_RS01830	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F8267_RS01835	COG0285	dihydrofolate synthase activity
F8267_RS01845	COG0586	Pfam SNARE associated Golgi protein
F8267_RS01855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F8267_RS01870	COG2814	Major facilitator Superfamily
F8267_RS01875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F8267_RS01890	COG3101	peptidyl-lysine hydroxylation
F8267_RS01895	COG0730	response to heat
F8267_RS01920	COG2062	phosphohistidine phosphatase, SixA
F8267_RS01935	COG3691	Protein conserved in bacteria
F8267_RS01945	COG2853	Lipoprotein
F8267_RS01950	COG2116	formate transmembrane transporter activity
F8267_RS01975	COG0590	tRNA wobble adenosine to inosine editing
F8267_RS01980	COG2807	transmembrane transport
F8267_RS01990	COG0436	Aminotransferase
F8267_RS01995	COG3275	phosphorelay sensor kinase activity
F8267_RS02000	COG3279	Response regulator of the LytR AlgR family
F8267_RS02015	COG3961	Belongs to the TPP enzyme family
F8267_RS02020	COG0667	Aldo Keto reductase
F8267_RS02035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F8267_RS02040	COG2199	diguanylate cyclase activity
F8267_RS02040	COG2200	EAL domain
F8267_RS02055	COG3415	Transposase
F8267_RS02060	COG3415	Transposase
F8267_RS02100	COG0583	DNA-binding transcription factor activity
F8267_RS02105	COG0385	Bile acid
F8267_RS02110	COG3530	Putative quorum-sensing-regulated virulence factor
F8267_RS02135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS02175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F8267_RS02180	COG4208	sulfate ABC transporter
F8267_RS02185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F8267_RS02190	COG4150	thiosulfate binding
F8267_RS02195	COG2837	iron assimilation
F8267_RS02215	COG0860	N-Acetylmuramoyl-L-alanine amidase
F8267_RS02235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F8267_RS02240	COG5342	invasion associated locus B
F8267_RS02250	COG0493	'glutamate synthase
F8267_RS02250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS02255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F8267_RS02265	COG1393	Belongs to the ArsC family
F8267_RS02280	COG0400	carboxylic ester hydrolase activity
F8267_RS02290	COG2321	neutral zinc metallopeptidase
F8267_RS02300	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F8267_RS02310	COG2716	regulation of RNA biosynthetic process
F8267_RS02315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F8267_RS02320	COG0628	permease
F8267_RS02325	COG4783	chaperone-mediated protein folding
F8267_RS02330	COG1393	Belongs to the ArsC family
F8267_RS02345	COG2233	PERMEase
F8267_RS02355	COG2723	6-phospho-beta-galactosidase activity
F8267_RS02365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F8267_RS02375	COG2211	Major facilitator Superfamily
F8267_RS02380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F8267_RS02395	COG0248	Ppx GppA phosphatase
F8267_RS02400	COG2200	EAL domain
F8267_RS02435	COG0516	GMP reductase activity
F8267_RS02435	COG0517	IMP dehydrogenase activity
F8267_RS02455	COG1645	bacterial-type flagellum-dependent swarming motility
F8267_RS02470	COG2976	Protein conserved in bacteria
F8267_RS02500	COG4953	penicillin-binding protein 1C
F8267_RS02505	COG2373	Large extracellular alpha-helical protein
F8267_RS02510	COG2897	thiosulfate sulfurtransferase activity
F8267_RS02525	COG2975	iron-sulfur cluster assembly
F8267_RS02530	COG0633	Ferredoxin
F8267_RS02550	COG0822	iron-sulfur transferase activity
F8267_RS02575	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F8267_RS02580	COG3683	transport system, periplasmic component
F8267_RS02585	COG3711	transcriptional antiterminator
F8267_RS02590	COG2814	Major facilitator Superfamily
F8267_RS02595	COG2259	Doxx family
F8267_RS02605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F8267_RS02605	COG1017	nitric oxide dioxygenase activity
F8267_RS02610	COG0347	Belongs to the P(II) protein family
F8267_RS02615	COG2204	response regulator
F8267_RS02620	COG3170	Tfp pilus assembly protein FimV
F8267_RS02625	COG2205	protein histidine kinase activity
F8267_RS02630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F8267_RS02630	COG0047	phosphoribosylformylglycinamidine synthase activity
F8267_RS02645	COG0560	Phosphoserine phosphatase
F8267_RS02650	COG1737	Transcriptional regulator
F8267_RS02655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS02665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F8267_RS02685	COG0681	Belongs to the peptidase S26 family
F8267_RS02695	COG3086	response to oxidative stress
F8267_RS02700	COG3026	antisigma factor binding
F8267_RS02705	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
F8267_RS02720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F8267_RS02730	COG0513	Belongs to the DEAD box helicase family
F8267_RS02745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F8267_RS02750	COG3118	belongs to the thioredoxin family
F8267_RS02765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F8267_RS02770	COG5544	Lipoprotein
F8267_RS02775	COG0477	Major facilitator Superfamily
F8267_RS02800	COG0542	response to heat
F8267_RS02815	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F8267_RS02820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F8267_RS02830	COG1605	Chorismate mutase
F8267_RS02830	COG0077	Prephenate dehydratase
F8267_RS02840	COG1605	Chorismate mutase
F8267_RS02840	COG0287	Prephenate dehydrogenase
F8267_RS02845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F8267_RS02855	COG2199	diguanylate cyclase activity
F8267_RS02860	COG2885	chlorophyll binding
F8267_RS02900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F8267_RS02905	COG4137	Cytochrome C assembly protein
F8267_RS02910	COG4536	flavin adenine dinucleotide binding
F8267_RS02925	COG0497	DNA recombination
F8267_RS02945	COG2867	negative regulation of translational initiation
F8267_RS02975	COG5290	Psort location Cytoplasmic, score
F8267_RS03010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F8267_RS03020	COG2169	Transcriptional regulator
F8267_RS03025	COG3813	Protein conserved in bacteria
F8267_RS03035	COG0243	molybdopterin cofactor binding
F8267_RS03040	COG3005	denitrification pathway
F8267_RS03045	COG3088	subunit of a heme lyase
F8267_RS03045	COG4235	cytochrome complex assembly
F8267_RS03050	COG4235	cytochrome complex assembly
F8267_RS03050	COG3088	subunit of a heme lyase
F8267_RS03055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F8267_RS03060	COG1138	Cytochrome C-type biogenesis protein
F8267_RS03070	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F8267_RS03075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F8267_RS03080	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F8267_RS03085	COG4133	protoheme IX ABC transporter activity
F8267_RS03090	COG0477	Major facilitator Superfamily
F8267_RS03095	COG0583	DNA-binding transcription factor activity
F8267_RS03100	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F8267_RS03105	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS03130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
F8267_RS03135	COG0747	negative chemotaxis
F8267_RS03140	COG0601	transmembrane transport
F8267_RS03145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F8267_RS03150	COG0444	Belongs to the ABC transporter superfamily
F8267_RS03155	COG4608	Belongs to the ABC transporter superfamily
F8267_RS03160	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS03165	COG3284	Transcriptional regulator
F8267_RS03170	COG0671	phosphoesterase, PA-phosphatase related
F8267_RS03175	COG0583	DNA-binding transcription factor activity
F8267_RS03185	COG0640	Transcriptional regulator
F8267_RS03190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F8267_RS03220	COG4575	ribosome binding
F8267_RS03230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F8267_RS03235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F8267_RS03245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F8267_RS03250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F8267_RS03260	COG4176	ABC-type proline glycine betaine transport system permease component
F8267_RS03275	COG1846	Transcriptional regulator
F8267_RS03285	COG1566	PFAM secretion protein HlyD family protein
F8267_RS03290	COG2814	Major facilitator Superfamily
F8267_RS03295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F8267_RS03315	COG1238	metal cluster binding
F8267_RS03320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F8267_RS03325	COG2823	Periplasmic or secreted lipoprotein
F8267_RS03355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F8267_RS03375	COG1546	Belongs to the CinA family
F8267_RS03380	COG0803	Belongs to the bacterial solute-binding protein 9 family
F8267_RS03385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F8267_RS03395	COG2951	lytic endotransglycosylase activity
F8267_RS03400	COG3730	PTS system glucitol sorbitol-specific
F8267_RS03405	COG3732	PTS system glucitol sorbitol-specific
F8267_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS03420	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS03425	COG1349	DNA-binding transcription factor activity
F8267_RS03450	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F8267_RS03455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F8267_RS03460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS03465	COG1609	Transcriptional regulator
F8267_RS03470	COG1263	PTS System
F8267_RS03470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS03475	COG2723	6-phospho-beta-galactosidase activity
F8267_RS03480	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F8267_RS03490	COG3260	NADH ubiquinone oxidoreductase 20
F8267_RS03495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F8267_RS03500	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F8267_RS03500	COG3261	NADH dehydrogenase
F8267_RS03505	COG0650	Formate hydrogenlyase subunit 4
F8267_RS03510	COG0651	ATP synthesis coupled electron transport
F8267_RS03515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS03530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F8267_RS03535	COG0298	carbon dioxide binding
F8267_RS03540	COG0409	Hydrogenase expression formation protein
F8267_RS03545	COG0309	Hydrogenase expression formation protein (HypE)
F8267_RS03560	COG1121	(ABC) transporter
F8267_RS03565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F8267_RS03570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F8267_RS03580	COG0583	DNA-binding transcription factor activity
F8267_RS03585	COG0679	Auxin Efflux Carrier
F8267_RS03605	COG3720	iron ion transport
F8267_RS03610	COG4558	Periplasmic binding protein
F8267_RS03615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS03650	COG3121	Chaperone
F8267_RS03665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F8267_RS03670	COG0163	prenyltransferase activity
F8267_RS03690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F8267_RS03695	COG4942	peptidase
F8267_RS03695	COG1388	LysM domain
F8267_RS03725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F8267_RS03755	COG2234	aminopeptidase activity
F8267_RS03775	COG0720	synthase
F8267_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS03785	COG0602	queuosine metabolic process
F8267_RS03805	COG3956	TIGRFAM MazG family protein
F8267_RS03810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F8267_RS03820	COG3850	Histidine kinase
F8267_RS03820	COG4999	Histidine kinase
F8267_RS03820	COG2205	protein histidine kinase activity
F8267_RS03820	COG3437	response regulator, receiver
F8267_RS03825	COG1929	Belongs to the glycerate kinase type-1 family
F8267_RS03830	COG4948	Mandelate Racemase Muconate Lactonizing
F8267_RS03835	COG4948	Mandelate Racemase Muconate Lactonizing
F8267_RS03840	COG2271	Major facilitator Superfamily
F8267_RS03845	COG0716	FMN binding
F8267_RS03850	COG0564	pseudouridine synthase activity
F8267_RS03855	COG3098	single-species biofilm formation
F8267_RS03870	COG1611	Belongs to the LOG family
F8267_RS03875	COG0814	amino acid
F8267_RS03880	COG1760	l-serine dehydratase
F8267_RS03895	COG2363	Small membrane protein
F8267_RS03900	COG0583	DNA-binding transcription factor activity
F8267_RS03905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F8267_RS03910	COG2166	iron-sulfur cluster assembly
F8267_RS03915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F8267_RS03920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F8267_RS03940	COG0860	N-Acetylmuramoyl-L-alanine amidase
F8267_RS03945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F8267_RS03945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F8267_RS03950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F8267_RS03960	COG1025	Belongs to the peptidase M16 family
F8267_RS03965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F8267_RS03980	COG4795	General secretion pathway protein
F8267_RS03985	COG2165	general secretion pathway protein
F8267_RS04015	COG0861	Integral membrane protein TerC family
F8267_RS04025	COG0667	Aldo Keto reductase
F8267_RS04040	COG1609	Transcriptional regulator
F8267_RS04050	COG1609	Transcriptional regulator
F8267_RS04060	COG0583	DNA-binding transcription factor activity
F8267_RS04065	COG1794	racemase activity, acting on amino acids and derivatives
F8267_RS04090	COG2814	Major facilitator Superfamily
F8267_RS04095	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS04100	COG0183	Belongs to the thiolase family
F8267_RS04105	COG0583	DNA-binding transcription factor activity
F8267_RS04115	COG0814	amino acid
F8267_RS04120	COG0667	Aldo Keto reductase
F8267_RS04135	COG0640	Transcriptional regulator
F8267_RS04150	COG0697	spore germination
F8267_RS04155	COG1846	Transcriptional regulator
F8267_RS04165	COG0154	amidase activity
F8267_RS04170	COG1960	acyl-CoA dehydrogenase activity
F8267_RS04180	COG4638	Rieske (2fe-2S)
F8267_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS04200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F8267_RS04215	COG3188	usher protein
F8267_RS04220	COG3121	Chaperone
F8267_RS04225	COG3539	Fimbrial protein
F8267_RS04245	COG0582	viral genome integration into host DNA
F8267_RS04250	COG4974	Belongs to the 'phage' integrase family
F8267_RS04260	COG3539	Fimbrial protein
F8267_RS04265	COG3121	Chaperone
F8267_RS04270	COG3188	usher protein
F8267_RS04275	COG3539	Fimbrial protein
F8267_RS04280	COG3539	Fimbrial protein
F8267_RS04285	COG3539	Fimbrial protein
F8267_RS04295	COG2388	GCN5-related N-acetyl-transferase
F8267_RS04300	COG3592	Divergent 4Fe-4S mono-cluster
F8267_RS04315	COG1289	transmembrane transporter activity
F8267_RS04320	COG1538	Outer membrane efflux protein
F8267_RS04325	COG3104	oligopeptide transport
F8267_RS04335	COG1982	Orn Lys Arg decarboxylase major
F8267_RS04340	COG0531	amino acid
F8267_RS04355	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F8267_RS04375	COG2271	Major facilitator Superfamily
F8267_RS04380	COG0483	inositol monophosphate 1-phosphatase activity
F8267_RS04385	COG1609	Transcriptional regulator
F8267_RS04390	COG0753	catalase activity
F8267_RS04400	COG0531	amino acid
F8267_RS04410	COG0124	histidyl-tRNA synthetase
F8267_RS04415	COG0124	histidyl-tRNA synthetase
F8267_RS04430	COG3539	Fimbrial protein
F8267_RS04440	COG3121	Chaperone
F8267_RS04445	COG3188	usher protein
F8267_RS04455	COG3539	Fimbrial protein
F8267_RS04490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F8267_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS04500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F8267_RS04505	COG3775	system Galactitol-specific IIC component
F8267_RS04510	COG3414	Phosphotransferase system galactitol-specific IIB component
F8267_RS04515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS04520	COG1349	DNA-binding transcription factor activity
F8267_RS04525	COG0698	ribose 5-phosphate isomerase
F8267_RS04530	COG3775	system Galactitol-specific IIC component
F8267_RS04535	COG3414	Phosphotransferase system galactitol-specific IIB component
F8267_RS04540	COG2213	PTS system mannitol-specific
F8267_RS04540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS04545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F8267_RS04590	COG4942	peptidase
F8267_RS04610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F8267_RS04620	COG4974	Belongs to the 'phage' integrase family
F8267_RS04625	COG0716	FMN binding
F8267_RS04635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F8267_RS04645	COG1272	protein, Hemolysin III
F8267_RS04655	COG1737	Transcriptional regulator
F8267_RS04660	COG2723	6-phospho-beta-galactosidase activity
F8267_RS04680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F8267_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS04705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F8267_RS04710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F8267_RS04715	COG0006	proline dipeptidase activity
F8267_RS04735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F8267_RS04740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F8267_RS04755	COG2968	Membrane
F8267_RS04760	COG1279	arginine transmembrane transporter activity
F8267_RS04765	COG0668	transmembrane transport
F8267_RS04770	COG0191	fructose-bisphosphate aldolase activity
F8267_RS04785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F8267_RS04790	COG0501	Belongs to the peptidase M48B family
F8267_RS04810	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
F8267_RS04815	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS04845	COG1414	Transcriptional regulator
F8267_RS04850	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS04865	COG2146	nitrite reductase [NAD(P)H] activity
F8267_RS04905	COG2814	Major facilitator Superfamily
F8267_RS04915	COG2356	endonuclease I
F8267_RS04920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F8267_RS04925	COG0189	ligase activity
F8267_RS04940	COG2197	response regulator
F8267_RS04945	COG2805	Type II/IV secretion system protein
F8267_RS04950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F8267_RS04955	COG0762	integral membrane protein
F8267_RS04970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F8267_RS04985	COG4214	carbohydrate transport
F8267_RS04995	COG3171	Protein conserved in bacteria
F8267_RS05005	COG1194	a g-specific adenine glycosylase
F8267_RS05020	COG2211	Major facilitator Superfamily
F8267_RS05025	COG1982	Orn Lys Arg decarboxylase major
F8267_RS05030	COG1811	Na channel or pump
F8267_RS05050	COG2731	YhcH YjgK YiaL family protein
F8267_RS05075	COG2186	Transcriptional regulator
F8267_RS05090	COG2382	esterase
F8267_RS05100	COG4771	TonB-dependent receptor
F8267_RS05110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F8267_RS05125	COG1917	Cupin 2, conserved barrel domain protein
F8267_RS05125	COG4977	sequence-specific DNA binding
F8267_RS05130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F8267_RS05135	COG3753	Protein conserved in bacteria
F8267_RS05140	COG1652	LysM domain
F8267_RS05145	COG0583	DNA-binding transcription factor activity
F8267_RS05155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F8267_RS05160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F8267_RS05175	COG2072	flavoprotein involved in K transport
F8267_RS05180	COG0583	DNA-binding transcription factor activity
F8267_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS05205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F8267_RS05210	COG0754	glutathionylspermidine amidase activity
F8267_RS05220	COG0625	glutathione transferase activity
F8267_RS05230	COG0848	biopolymer transport protein
F8267_RS05240	COG0626	cystathionine gamma-synthase activity
F8267_RS05245	COG0586	Pfam SNARE associated Golgi protein
F8267_RS05250	COG2207	Transcriptional regulator
F8267_RS05255	COG1979	alcohol dehydrogenase
F8267_RS05260	COG0656	L-ascorbic acid biosynthetic process
F8267_RS05270	COG1032	radical SAM domain protein
F8267_RS05280	COG0204	Acyl-transferase
F8267_RS05290	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F8267_RS05295	COG3111	PFAM Bacterial OB fold (BOF) protein
F8267_RS05305	COG0642	Histidine kinase
F8267_RS05310	COG2249	NAD(P)H dehydrogenase (quinone) activity
F8267_RS05315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F8267_RS05320	COG0187	DNA topoisomerase II activity
F8267_RS05325	COG3150	esterase
F8267_RS05330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F8267_RS05335	COG3151	Protein conserved in bacteria
F8267_RS05340	COG0494	nUDIX hydrolase
F8267_RS05355	COG0754	glutathionylspermidine amidase activity
F8267_RS05360	COG3384	dioxygenase
F8267_RS05370	COG2960	long-chain fatty acid transporting porin activity
F8267_RS05395	COG3025	triphosphatase activity
F8267_RS05400	COG4991	sh3 domain protein
F8267_RS05415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F8267_RS05425	COG0477	Major facilitator Superfamily
F8267_RS05435	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F8267_RS05440	COG0358	DNA primase activity
F8267_RS05450	COG3663	DNA glycosylase
F8267_RS05490	COG3119	arylsulfatase activity
F8267_RS05495	COG0641	radical SAM
F8267_RS05500	COG0714	Associated with various cellular activities
F8267_RS05535	COG0641	radical SAM
F8267_RS05560	COG2376	Dihydroxyacetone kinase
F8267_RS05565	COG1461	Dihydroxyacetone kinase
F8267_RS05580	COG2375	cellular response to nickel ion
F8267_RS05585	COG1695	Transcriptional regulator
F8267_RS05595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F8267_RS05600	COG1609	Transcriptional regulator
F8267_RS05605	COG3250	beta-galactosidase activity
F8267_RS05610	COG2731	YhcH YjgK YiaL family protein
F8267_RS05615	COG0531	amino acid
F8267_RS05620	COG0531	amino acid
F8267_RS05630	COG3408	Glycogen debranching enzyme
F8267_RS05630	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F8267_RS05675	COG1902	pentaerythritol trinitrate reductase activity
F8267_RS05675	COG0446	pyridine nucleotide-disulphide oxidoreductase
F8267_RS05685	COG1451	nucleotide metabolic process
F8267_RS05690	COG0673	inositol 2-dehydrogenase activity
F8267_RS05695	COG0861	Integral membrane protein TerC family
F8267_RS05705	COG2721	sulfolactate sulfo-lyase activity
F8267_RS05715	COG2271	Major facilitator Superfamily
F8267_RS05720	COG2186	Transcriptional regulator
F8267_RS05725	COG0586	Pfam SNARE associated Golgi protein
F8267_RS05735	COG1422	Protein of unknown function (DUF1090)
F8267_RS05740	COG4575	ribosome binding
F8267_RS05745	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F8267_RS05760	COG2259	Doxx family
F8267_RS05765	COG0435	Glutathione S-transferase
F8267_RS05770	COG3152	Membrane
F8267_RS05775	COG0583	DNA-binding transcription factor activity
F8267_RS05780	COG1741	Belongs to the pirin family
F8267_RS05790	COG0668	transmembrane transport
F8267_RS05800	COG1929	Belongs to the glycerate kinase type-1 family
F8267_RS05805	COG2084	Dehydrogenase
F8267_RS05815	COG2721	sulfolactate sulfo-lyase activity
F8267_RS05820	COG1349	DNA-binding transcription factor activity
F8267_RS05830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS05840	COG3716	PTS system mannose fructose sorbose family IID component
F8267_RS05845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS05850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F8267_RS05855	COG2222	sugar isomerase
F8267_RS05870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F8267_RS05890	COG2823	Periplasmic or secreted lipoprotein
F8267_RS05895	COG0701	Predicted permease
F8267_RS05900	COG0702	epimerase
F8267_RS05905	COG0693	protein deglycase activity
F8267_RS05920	COG3153	acetyltransferase
F8267_RS05925	COG3154	lipid carrier protein
F8267_RS05930	COG0826	peptidase U32
F8267_RS05935	COG0826	peptidase U32
F8267_RS05940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS05945	COG0814	amino acid
F8267_RS05990	COG0195	Participates in both transcription termination and antitermination
F8267_RS06035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F8267_RS06045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F8267_RS06050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F8267_RS06060	COG1534	Rna-binding protein
F8267_RS06070	COG2027	D-alanyl-D-alanine carboxypeptidase
F8267_RS06080	COG0697	spore germination
F8267_RS06095	COG0142	geranyltranstransferase activity
F8267_RS06100	COG3423	Transcriptional regulator
F8267_RS06110	COG5007	Belongs to the BolA IbaG family
F8267_RS06115	COG3113	response to antibiotic
F8267_RS06120	COG2854	intermembrane phospholipid transfer
F8267_RS06125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F8267_RS06130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F8267_RS06135	COG1127	ABC transporter
F8267_RS06140	COG0530	calcium, potassium:sodium antiporter activity
F8267_RS06150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F8267_RS06155	COG3117	lipopolysaccharide transmembrane transporter activity
F8267_RS06160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F8267_RS06165	COG1137	ATPase activity
F8267_RS06170	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F8267_RS06175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F8267_RS06180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS06190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS06195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F8267_RS06200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F8267_RS06205	COG5002	protein histidine kinase activity
F8267_RS06205	COG0784	Response regulator, receiver
F8267_RS06205	COG2198	Histidine kinase
F8267_RS06210	COG1242	4 iron, 4 sulfur cluster binding
F8267_RS06215	COG0067	glutamate synthase
F8267_RS06215	COG0070	glutamate synthase
F8267_RS06215	COG0069	glutamate synthase activity
F8267_RS06220	COG0493	'glutamate synthase
F8267_RS06225	COG2969	positive regulation of protein catabolic process
F8267_RS06230	COG0625	glutathione transferase activity
F8267_RS06245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F8267_RS06250	COG3105	Protein conserved in bacteria
F8267_RS06255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F8267_RS06260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F8267_RS06295	COG2732	(Barnase) inhibitor
F8267_RS06300	COG1289	transmembrane transporter activity
F8267_RS06315	COG0583	DNA-binding transcription factor activity
F8267_RS06320	COG0312	modulator of DNA gyrase
F8267_RS06325	COG3164	Protein of unknown function
F8267_RS06330	COG1530	ribonuclease E activity
F8267_RS06340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F8267_RS06345	COG1792	Involved in formation and maintenance of cell shape
F8267_RS06350	COG1077	Cell shape determining protein MreB Mrl
F8267_RS06355	COG2199	diguanylate cyclase activity
F8267_RS06355	COG2200	EAL domain
F8267_RS06360	COG0604	alcohol dehydrogenase
F8267_RS06375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F8267_RS06380	COG0511	ligase activity, forming carbon-carbon bonds
F8267_RS06385	COG0439	Biotin carboxylase
F8267_RS06390	COG3924	membrane
F8267_RS06395	COG4145	pantothenate transmembrane transporter activity
F8267_RS06415	COG1309	transcriptional regulator
F8267_RS06420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS06425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F8267_RS06465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F8267_RS06485	COG0551	DNA topoisomerase type I activity
F8267_RS06495	COG0758	DNA mediated transformation
F8267_RS06525	COG3036	rescue of stalled ribosome
F8267_RS06530	COG0789	Transcriptional regulator
F8267_RS06555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F8267_RS06570	COG0201	protein transport
F8267_RS06635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F8267_RS06650	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F8267_RS06675	COG0051	transcription antitermination factor activity, RNA binding
F8267_RS06730	COG2964	Protein conserved in bacteria
F8267_RS06735	COG0545	Peptidyl-prolyl cis-trans isomerase
F8267_RS06745	COG1047	Peptidyl-prolyl cis-trans
F8267_RS06750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F8267_RS06765	COG0488	(ABC) transporter
F8267_RS06775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F8267_RS06785	COG0429	hydrolase of the alpha beta-hydrolase fold
F8267_RS06795	COG3954	Phosphoribulokinase
F8267_RS06800	COG1765	OsmC-like protein
F8267_RS06810	COG1289	transmembrane transporter activity
F8267_RS06815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F8267_RS06825	COG2184	nucleotidyltransferase activity
F8267_RS06840	COG0738	Major facilitator superfamily
F8267_RS06845	COG0402	S-adenosylhomocysteine deaminase activity
F8267_RS06850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F8267_RS06855	COG2146	nitrite reductase [NAD(P)H] activity
F8267_RS06875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F8267_RS06880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F8267_RS06885	COG3266	domain, Protein
F8267_RS06900	COG4796	Type ii and iii secretion system protein
F8267_RS06925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F8267_RS06930	COG0494	nUDIX hydrolase
F8267_RS06940	COG1011	Hydrolase
F8267_RS06945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F8267_RS06965	COG0745	RESPONSE REGULATOR receiver
F8267_RS06970	COG0738	Major facilitator superfamily
F8267_RS06975	COG3254	rhamnose metabolic process
F8267_RS06990	COG4948	Mandelate Racemase Muconate Lactonizing
F8267_RS06995	COG0179	Fumarylacetoacetate (FAA) hydrolase
F8267_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS07010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F8267_RS07015	COG2183	response to ionizing radiation
F8267_RS07020	COG1918	ferrous iron import across plasma membrane
F8267_RS07045	COG1040	competence protein
F8267_RS07055	COG2610	gluconate transmembrane transporter activity
F8267_RS07060	COG1640	4-alpha-glucanotransferase
F8267_RS07065	COG0058	SHG alpha-glucan phosphorylase activity
F8267_RS07075	COG1349	DNA-binding transcription factor activity
F8267_RS07090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F8267_RS07095	COG0058	SHG alpha-glucan phosphorylase activity
F8267_RS07120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F8267_RS07125	COG2610	gluconate transmembrane transporter activity
F8267_RS07130	COG3265	gluconokinase activity
F8267_RS07135	COG1609	Transcriptional regulator
F8267_RS07140	COG1741	Belongs to the pirin family
F8267_RS07145	COG0673	inositol 2-dehydrogenase activity
F8267_RS07155	COG1247	-acetyltransferase
F8267_RS07160	COG0405	Gamma-glutamyltransferase
F8267_RS07170	COG0584	glycerophosphoryl diester phosphodiesterase
F8267_RS07210	COG0411	ABC transporter
F8267_RS07220	COG0559	Belongs to the binding-protein-dependent transport system permease family
F8267_RS07225	COG0683	leucine binding
F8267_RS07235	COG0683	leucine binding
F8267_RS07245	COG2177	Part of the ABC transporter FtsEX involved in
F8267_RS07250	COG2884	Cell division ATP-binding protein ftsE
F8267_RS07255	COG0552	protein localization to endoplasmic reticulum
F8267_RS07260	COG0742	ribosomal rna small subunit methyltransferase
F8267_RS07265	COG3776	membrane
F8267_RS07275	COG3714	YhhN family
F8267_RS07290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F8267_RS07300	COG0477	Major facilitator Superfamily
F8267_RS07320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F8267_RS07330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F8267_RS07330	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F8267_RS07365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F8267_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS07380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F8267_RS07385	COG2091	lysine biosynthetic process via aminoadipic acid
F8267_RS07425	COG3479	Phenolic acid decarboxylase
F8267_RS07435	COG0747	negative chemotaxis
F8267_RS07440	COG0601	transmembrane transport
F8267_RS07445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F8267_RS07475	COG2239	Acts as a magnesium transporter
F8267_RS07480	COG2081	HI0933 family
F8267_RS07485	COG0306	phosphate transporter
F8267_RS07495	COG0589	response to stress
F8267_RS07515	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F8267_RS07520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F8267_RS07530	COG2610	gluconate transmembrane transporter activity
F8267_RS07535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F8267_RS07540	COG1609	Transcriptional regulator
F8267_RS07545	COG0625	glutathione transferase activity
F8267_RS07550	COG1454	alcohol dehydrogenase
F8267_RS07560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F8267_RS07570	COG2197	response regulator
F8267_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS07580	COG0583	DNA-binding transcription factor activity
F8267_RS07585	COG1295	ribonuclease BN
F8267_RS07590	COG0477	Major facilitator Superfamily
F8267_RS07595	COG2982	Protein involved in outer membrane biogenesis
F8267_RS07605	COG0612	Peptidase, M16
F8267_RS07615	COG2200	EAL domain
F8267_RS07615	COG2199	diguanylate cyclase activity
F8267_RS07620	COG0457	Tetratricopeptide repeat
F8267_RS07620	COG3118	belongs to the thioredoxin family
F8267_RS07625	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F8267_RS07630	COG1215	transferase activity, transferring glycosyl groups
F8267_RS07660	COG2194	sulfuric ester hydrolase activity
F8267_RS07680	COG4608	Belongs to the ABC transporter superfamily
F8267_RS07685	COG0444	Belongs to the ABC transporter superfamily
F8267_RS07690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F8267_RS07695	COG0601	transmembrane transport
F8267_RS07700	COG0747	negative chemotaxis
F8267_RS07715	COG2223	nitrite transmembrane transporter activity
F8267_RS07720	COG5571	outer membrane autotransporter
F8267_RS07725	COG2818	Glycosylase
F8267_RS07730	COG0456	acetyltransferase
F8267_RS07735	COG0243	molybdopterin cofactor binding
F8267_RS07740	COG2885	chlorophyll binding
F8267_RS07745	COG1609	Transcriptional regulator
F8267_RS07755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F8267_RS07775	COG2814	Major facilitator Superfamily
F8267_RS07780	COG2944	sequence-specific DNA binding
F8267_RS07785	COG1278	Cold shock
F8267_RS07790	COG0488	(ABC) transporter
F8267_RS07810	COG3274	enterobacterial common antigen metabolic process
F8267_RS07815	COG4682	membrane
F8267_RS07820	COG1070	Carbohydrate kinase
F8267_RS07830	COG4213	ABC transporter substrate-binding protein
F8267_RS07840	COG4214	carbohydrate transport
F8267_RS07845	COG2207	Transcriptional regulator
F8267_RS07845	COG1609	Transcriptional regulator
F8267_RS07850	COG2992	FlgJ-related protein
F8267_RS07855	COG0366	Alpha amylase catalytic
F8267_RS07860	COG3977	Valine--pyruvate aminotransferase
F8267_RS07865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS07870	COG1454	alcohol dehydrogenase
F8267_RS07875	COG3276	selenocysteine insertion sequence binding
F8267_RS07885	COG0625	glutathione transferase activity
F8267_RS07890	COG1566	PFAM secretion protein HlyD family protein
F8267_RS07910	COG3722	fumarate hydratase activity
F8267_RS07930	COG2186	Transcriptional regulator
F8267_RS07940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F8267_RS07960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F8267_RS07965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F8267_RS07975	COG4942	peptidase
F8267_RS07980	COG2861	carbohydrate metabolic process
F8267_RS07985	COG0463	Glycosyl transferase, family 2
F8267_RS08000	COG0156	8-amino-7-oxononanoate synthase activity
F8267_RS08015	COG0859	PFAM glycosyl transferase family 9
F8267_RS08020	COG0859	PFAM glycosyl transferase family 9
F8267_RS08025	COG0438	transferase activity, transferring glycosyl groups
F8267_RS08040	COG1216	Glycosyl transferase, family 2
F8267_RS08055	COG1519	Transferase
F8267_RS08080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F8267_RS08090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F8267_RS08115	COG1561	YicC-like family, N-terminal region
F8267_RS08120	COG2860	membrane
F8267_RS08125	COG2194	sulfuric ester hydrolase activity
F8267_RS08135	COG0194	GDP metabolic process
F8267_RS08145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F8267_RS08150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F8267_RS08155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F8267_RS08160	COG1494	fructose-1,6-bisphosphatase
F8267_RS08170	COG3152	Membrane
F8267_RS08195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F8267_RS08200	COG3074	FtsZ-dependent cytokinesis
F8267_RS08215	COG0786	glutamate:sodium symporter activity
F8267_RS08220	COG2233	PERMEase
F8267_RS08225	COG2982	Protein involved in outer membrane biogenesis
F8267_RS08230	COG1263	PTS System
F8267_RS08230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS08235	COG1486	melibiose metabolic process
F8267_RS08250	COG1940	carbohydrate kinase activity
F8267_RS08255	COG0191	fructose-bisphosphate aldolase activity
F8267_RS08265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS08265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS08270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS08275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS08275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS08275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS08280	COG3711	transcriptional antiterminator
F8267_RS08285	COG1501	Belongs to the glycosyl hydrolase 31 family
F8267_RS08290	COG2211	Major facilitator Superfamily
F8267_RS08335	COG1064	alcohol dehydrogenase
F8267_RS08345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F8267_RS08355	COG1464	Belongs to the NlpA lipoprotein family
F8267_RS08360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS08360	COG1263	PTS System
F8267_RS08375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F8267_RS08425	COG0697	spore germination
F8267_RS08435	COG1609	Transcriptional regulator
F8267_RS08445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F8267_RS08445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F8267_RS08450	COG4580	involved in the transport of maltose and maltodextrins
F8267_RS08475	COG2188	Transcriptional regulator
F8267_RS08505	COG2271	Major facilitator Superfamily
F8267_RS08515	COG2197	response regulator
F8267_RS08520	COG0440	acetolactate synthase activity
F8267_RS08525	COG0028	Belongs to the TPP enzyme family
F8267_RS08555	COG2814	Major facilitator Superfamily
F8267_RS08560	COG0583	DNA-binding transcription factor activity
F8267_RS08565	COG2610	gluconate transmembrane transporter activity
F8267_RS08585	COG2149	membrane
F8267_RS08600	COG2188	Transcriptional regulator
F8267_RS08620	COG5645	(Lipo)protein
F8267_RS08625	COG0823	Involved in the tonB-independent uptake of proteins
F8267_RS08630	COG2271	Major facilitator Superfamily
F8267_RS08640	COG0800	Aldolase
F8267_RS08645	COG3734	2-keto-3-deoxy-galactonokinase
F8267_RS08650	COG2186	Transcriptional regulator
F8267_RS08665	COG0561	phosphatase activity
F8267_RS08670	COG0187	DNA topoisomerase II activity
F8267_RS08680	COG0592	DNA-directed DNA polymerase activity
F8267_RS08690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F8267_RS08700	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F8267_RS08725	COG2091	lysine biosynthetic process via aminoadipic acid
F8267_RS08730	COG0431	NADPH-dependent FMN reductase
F8267_RS08735	COG2252	PERMEase
F8267_RS08745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F8267_RS08750	COG0363	glucosamine-6-phosphate deaminase activity
F8267_RS08755	COG2382	esterase
F8267_RS08765	COG0704	Plays a role in the regulation of phosphate uptake
F8267_RS08775	COG0581	inorganic phosphate transmembrane transporter activity
F8267_RS08780	COG0573	inorganic phosphate transmembrane transporter activity
F8267_RS08785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F8267_RS08795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F8267_RS08805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F8267_RS08810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F8267_RS08845	COG3312	ion transport
F8267_RS08860	COG0716	FMN binding
F8267_RS08865	COG1522	sequence-specific DNA binding
F8267_RS08895	COG1129	ABC transporter
F8267_RS08900	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS08910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F8267_RS08915	COG1609	Transcriptional regulator
F8267_RS08920	COG0477	Major facilitator Superfamily
F8267_RS08925	COG2186	Transcriptional regulator
F8267_RS08970	COG3085	chromosome segregation
F8267_RS08975	COG0606	chelatase, subunit chli
F8267_RS08990	COG3978	acetolactate synthase activity
F8267_RS08995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F8267_RS09005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F8267_RS09010	COG0583	DNA-binding transcription factor activity
F8267_RS09020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F8267_RS09025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F8267_RS09035	COG1811	Na channel or pump
F8267_RS09045	COG0583	DNA-binding transcription factor activity
F8267_RS09060	COG3118	belongs to the thioredoxin family
F8267_RS09065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F8267_RS09070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F8267_RS09080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F8267_RS09085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F8267_RS09090	COG1088	dTDP-glucose 4,6-dehydratase activity
F8267_RS09095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F8267_RS09100	COG0456	acetyltransferase
F8267_RS09105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F8267_RS09110	COG2244	polysaccharide biosynthetic process
F8267_RS09160	COG3071	HemY protein
F8267_RS09165	COG2959	enzyme of heme biosynthesis
F8267_RS09170	COG1587	Uroporphyrinogen-III synthase
F8267_RS09180	COG3072	Adenylate cyclase
F8267_RS09205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F8267_RS09210	COG1011	Hydrolase
F8267_RS09215	COG0210	DNA helicase
F8267_RS09230	COG2050	protein possibly involved in aromatic compounds catabolism
F8267_RS09245	COG1280	lysine exporter protein (LysE YggA)
F8267_RS09255	COG1280	lysine exporter protein (LysE YggA)
F8267_RS09260	COG2267	carboxylic ester hydrolase activity
F8267_RS09265	COG0561	phosphatase activity
F8267_RS09270	COG0697	spore germination
F8267_RS09275	COG0583	DNA-binding transcription factor activity
F8267_RS09305	COG3165	ubiquinone biosynthetic process from chorismate
F8267_RS09315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F8267_RS09325	COG0805	protein transport
F8267_RS09365	COG1739	Uncharacterized protein family UPF0029
F8267_RS09375	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
F8267_RS09400	COG1763	Mo-molybdopterin cofactor biosynthetic process
F8267_RS09410	COG3084	Protein conserved in bacteria
F8267_RS09415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F8267_RS09425	COG0204	Acyl-transferase
F8267_RS09445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F8267_RS09455	COG3852	Histidine kinase
F8267_RS09470	COG1011	Hydrolase
F8267_RS09485	COG0456	acetyltransferase
F8267_RS09490	COG0657	acetylesterase activity
F8267_RS09500	COG2864	formate dehydrogenase
F8267_RS09505	COG0437	4 iron, 4 sulfur cluster binding
F8267_RS09530	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F8267_RS09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F8267_RS09545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F8267_RS09550	COG2731	YhcH YjgK YiaL family protein
F8267_RS09555	COG2271	Major facilitator Superfamily
F8267_RS09565	COG1454	alcohol dehydrogenase
F8267_RS09600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F8267_RS09605	COG2258	MOSC domain
F8267_RS09610	COG2205	protein histidine kinase activity
F8267_RS09615	COG0745	RESPONSE REGULATOR receiver
F8267_RS09620	COG3678	ATP-independent chaperone mediated protein folding
F8267_RS09640	COG1575	Belongs to the MenA family. Type 1 subfamily
F8267_RS09655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F8267_RS09660	COG1609	Transcriptional regulator
F8267_RS09665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F8267_RS09680	COG0626	cystathionine gamma-synthase activity
F8267_RS09685	COG0527	aspartate kinase activity
F8267_RS09685	COG0460	homoserine dehydrogenase
F8267_RS09695	COG0697	spore germination
F8267_RS09700	COG0371	Dehydrogenase
F8267_RS09710	COG2207	Transcriptional regulator
F8267_RS09715	COG3443	Belongs to the bacterial solute-binding protein 9 family
F8267_RS09730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F8267_RS09745	COG0583	DNA-binding transcription factor activity
F8267_RS09850	COG0250	Participates in transcription elongation, termination and antitermination
F8267_RS09885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F8267_RS09890	COG1447	Phosphotransferase system cellobiose-specific component IIA
F8267_RS09900	COG3706	GGDEF domain
F8267_RS09915	COG2104	thiamine diphosphate biosynthetic process
F8267_RS09920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F8267_RS09935	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F8267_RS09975	COG4191	Histidine kinase
F8267_RS09985	COG0151	Belongs to the GarS family
F8267_RS10025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F8267_RS10045	COG1410	methionine synthase
F8267_RS10045	COG0646	methionine synthase
F8267_RS10050	COG1283	sodium-dependent phosphate transmembrane transporter activity
F8267_RS10065	COG1187	pseudouridine synthase activity
F8267_RS10080	COG4650	regulator
F8267_RS10090	COG1690	Belongs to the RtcB family
F8267_RS10095	COG3541	Predicted nucleotidyltransferase
F8267_RS10100	COG0527	aspartate kinase activity
F8267_RS10110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F8267_RS10115	COG0251	oxidation-reduction process
F8267_RS10160	COG4580	involved in the transport of maltose and maltodextrins
F8267_RS10185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F8267_RS10195	COG0534	Mate efflux family protein
F8267_RS10200	COG3237	CsbD-like
F8267_RS10205	COG0735	belongs to the Fur family
F8267_RS10215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F8267_RS10230	COG0305	Participates in initiation and elongation during chromosome replication
F8267_RS10235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F8267_RS10240	COG1448	Aminotransferase
F8267_RS10250	COG0432	Pfam Uncharacterised protein family UPF0047
F8267_RS10255	COG2315	Protein conserved in bacteria
F8267_RS10270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F8267_RS10295	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F8267_RS10310	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F8267_RS10320	COG0789	Transcriptional regulator
F8267_RS10325	COG0625	glutathione transferase activity
F8267_RS10330	COG2252	PERMEase
F8267_RS10335	COG0025	NhaP-type Na H and K H
F8267_RS10340	COG0583	DNA-binding transcription factor activity
F8267_RS10350	COG1346	cytolysis
F8267_RS10360	COG3539	Fimbrial protein
F8267_RS10375	COG3539	Fimbrial protein
F8267_RS10380	COG3539	Fimbrial protein
F8267_RS10390	COG3162	membrane
F8267_RS10395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F8267_RS10400	COG1301	dicarboxylic acid transport
F8267_RS10405	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F8267_RS10430	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS10435	COG1129	ABC transporter
F8267_RS10440	COG4191	Histidine kinase
F8267_RS10440	COG0784	Response regulator, receiver
F8267_RS10450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F8267_RS10460	COG3454	Phosphonate metabolism
F8267_RS10465	COG4778	phosphonate C-P lyase system protein PhnL
F8267_RS10470	COG4107	phosphonate C-P lyase system protein PhnK
F8267_RS10475	COG3627	carbon phosphorus lyase activity
F8267_RS10480	COG3626	phosphonate metabolism
F8267_RS10485	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F8267_RS10490	COG3624	Phosphonate C-P lyase system protein PhnG
F8267_RS10495	COG2188	Transcriptional regulator
F8267_RS10500	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F8267_RS10505	COG2824	Alkylphosphonate utilization operon protein PhnA
F8267_RS10515	COG2169	Transcriptional regulator
F8267_RS10520	COG1486	melibiose metabolic process
F8267_RS10550	COG0861	Integral membrane protein TerC family
F8267_RS10565	COG1215	transferase activity, transferring glycosyl groups
F8267_RS10570	COG0726	polysaccharide deacetylase
F8267_RS10570	COG1649	PFAM Uncharacterised BCR, COG1649
F8267_RS10575	COG0457	Tetratricopeptide repeat
F8267_RS10610	COG1309	transcriptional regulator
F8267_RS10625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F8267_RS10630	COG1027	Aspartate ammonia-lyase
F8267_RS10635	COG3030	protein affecting phage T7 exclusion by the F plasmid
F8267_RS10640	COG0531	amino acid
F8267_RS10650	COG0459	protein refolding
F8267_RS10705	COG1509	lysine 2,3-aminomutase activity
F8267_RS10720	COG5510	response to toxic substance
F8267_RS10725	COG2076	Multidrug Resistance protein
F8267_RS10745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F8267_RS10750	COG1053	succinate dehydrogenase
F8267_RS10765	COG1511	domain protein
F8267_RS10765	COG3264	Mechanosensitive ion channel
F8267_RS10780	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F8267_RS10785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS10805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F8267_RS10810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F8267_RS10810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F8267_RS10815	COG0802	atpase or kinase
F8267_RS10820	COG0860	N-Acetylmuramoyl-L-alanine amidase
F8267_RS10840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F8267_RS10845	COG0330	HflC and HflK could
F8267_RS10850	COG0330	HflC and HflK could
F8267_RS10855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F8267_RS10870	COG0557	exoribonuclease II activity
F8267_RS10875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F8267_RS10880	COG0477	Major facilitator Superfamily
F8267_RS10885	COG1960	acyl-CoA dehydrogenase activity
F8267_RS10895	COG3650	response to hydrogen peroxide
F8267_RS10900	COG1073	alpha beta
F8267_RS10960	COG2965	DNA replication, synthesis of RNA primer
F8267_RS10965	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F8267_RS10970	COG0359	binds to the 23S rRNA
F8267_RS10980	COG3061	Opacity-associated protein A
F8267_RS10985	COG0545	Peptidyl-prolyl cis-trans isomerase
F8267_RS10990	COG1113	amino acid transport
F8267_RS11000	COG0697	spore germination
F8267_RS11010	COG0702	epimerase
F8267_RS11015	COG1733	regulation of RNA biosynthetic process
F8267_RS11030	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F8267_RS11040	COG1253	flavin adenine dinucleotide binding
F8267_RS11050	COG0729	surface antigen
F8267_RS11055	COG2911	Protein conserved in bacteria
F8267_RS11060	COG2105	PFAM AIG2 family protein
F8267_RS11070	COG1879	ABC-type sugar transport system periplasmic component
F8267_RS11075	COG1129	ABC transporter
F8267_RS11080	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS11085	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS11095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F8267_RS11110	COG0312	modulator of DNA gyrase
F8267_RS11145	COG3964	amidohydrolase
F8267_RS11160	COG2706	6-phosphogluconolactonase activity
F8267_RS11165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS11165	COG3711	transcriptional antiterminator
F8267_RS11170	COG0602	queuosine metabolic process
F8267_RS11190	COG1486	melibiose metabolic process
F8267_RS11195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F8267_RS11200	COG0366	Alpha amylase catalytic
F8267_RS11205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS11205	COG1263	PTS System
F8267_RS11220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F8267_RS11225	COG0251	oxidation-reduction process
F8267_RS11245	COG2731	YhcH YjgK YiaL family protein
F8267_RS11250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F8267_RS11270	COG0525	valine-tRNA ligase activity
F8267_RS11275	COG2927	DNA polymerase III (CHI subunit)
F8267_RS11285	COG0795	lipopolysaccharide-transporting ATPase activity
F8267_RS11290	COG0795	lipopolysaccharide-transporting ATPase activity
F8267_RS11300	COG0433	COG0433 Predicted ATPase
F8267_RS11315	COG3718	enzyme involved in inositol metabolism
F8267_RS11320	COG0837	glucose binding
F8267_RS11320	COG1737	Transcriptional regulator
F8267_RS11325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F8267_RS11330	COG3962	Belongs to the TPP enzyme family
F8267_RS11340	COG1082	Xylose isomerase domain protein TIM barrel
F8267_RS11350	COG2814	Major facilitator Superfamily
F8267_RS11360	COG3842	ATPase activity
F8267_RS11365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F8267_RS11370	COG0395	ABC-type sugar transport system, permease component
F8267_RS11375	COG1175	transmembrane transport
F8267_RS11380	COG1064	alcohol dehydrogenase
F8267_RS11385	COG0659	secondary active sulfate transmembrane transporter activity
F8267_RS11390	COG0288	reversible hydration of carbon dioxide
F8267_RS11405	COG1401	restriction endodeoxyribonuclease activity
F8267_RS11415	COG1196	nuclear chromosome segregation
F8267_RS11440	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
F8267_RS11470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F8267_RS11475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS11480	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS11485	COG1538	Outer membrane efflux protein
F8267_RS11490	COG0745	RESPONSE REGULATOR receiver
F8267_RS11495	COG5002	protein histidine kinase activity
F8267_RS11500	COG2850	peptidyl-arginine hydroxylation
F8267_RS11530	COG0842	Transport permease protein
F8267_RS11535	COG0842	Transport permease protein
F8267_RS11535	COG1129	ABC transporter
F8267_RS11540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS11545	COG3706	GGDEF domain
F8267_RS11570	COG4869	propanediol catabolic process
F8267_RS11580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F8267_RS11585	COG1882	Formate acetyltransferase
F8267_RS11600	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS11600	COG1454	alcohol dehydrogenase
F8267_RS11645	COG3716	PTS system mannose fructose sorbose family IID component
F8267_RS11650	COG3715	PTS system
F8267_RS11655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS11655	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS11675	COG0531	amino acid
F8267_RS11685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F8267_RS11690	COG5457	Domain of unknown function (DUF1127)
F8267_RS11700	COG1566	PFAM secretion protein HlyD family protein
F8267_RS11715	COG0700	Nucleoside recognition
F8267_RS11720	COG1473	amidohydrolase
F8267_RS11730	COG1924	4 iron, 4 sulfur cluster binding
F8267_RS11735	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
F8267_RS11745	COG2814	Major facilitator Superfamily
F8267_RS11750	COG2733	membrane
F8267_RS11760	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS11765	COG0523	cobalamin synthesis protein
F8267_RS11770	COG2879	small protein
F8267_RS11775	COG1966	Carbon starvation protein
F8267_RS11780	COG2831	hemolysin activation secretion protein
F8267_RS11785	COG3210	domain, Protein
F8267_RS11795	COG3210	domain, Protein
F8267_RS11815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F8267_RS11820	COG2368	4-hydroxyphenylacetate
F8267_RS11840	COG3971	2-oxopent-4-enoate hydratase activity
F8267_RS11850	COG3384	dioxygenase
F8267_RS11855	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS11865	COG0179	Fumarylacetoacetate (FAA) hydrolase
F8267_RS11875	COG1846	Transcriptional regulator
F8267_RS11880	COG2271	Major facilitator Superfamily
F8267_RS11885	COG1802	Transcriptional regulator
F8267_RS11890	COG1063	alcohol dehydrogenase
F8267_RS11910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F8267_RS11925	COG3734	2-keto-3-deoxy-galactonokinase
F8267_RS11930	COG0800	Aldolase
F8267_RS11935	COG1737	Transcriptional regulator
F8267_RS11935	COG0837	glucose binding
F8267_RS11960	COG1484	DNA-dependent DNA replication
F8267_RS11975	COG2966	Psort location CytoplasmicMembrane, score
F8267_RS11990	COG2197	response regulator
F8267_RS11995	COG2197	response regulator
F8267_RS12000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F8267_RS12005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F8267_RS12010	COG4114	ferric iron reductase
F8267_RS12015	COG3706	GGDEF domain
F8267_RS12045	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F8267_RS12050	COG0456	acetyltransferase
F8267_RS12055	COG1011	Hydrolase
F8267_RS12065	COG2823	Periplasmic or secreted lipoprotein
F8267_RS12070	COG5487	UPF0391 membrane protein
F8267_RS12075	COG4667	esterase of the alpha-beta hydrolase superfamily
F8267_RS12080	COG0084	hydrolase, TatD family'
F8267_RS12110	COG3726	membrane protein affecting hemolysin expression
F8267_RS12115	COG0560	Phosphoserine phosphatase
F8267_RS12120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F8267_RS12130	COG0488	(ABC) transporter
F8267_RS12135	COG0741	lytic transglycosylase activity
F8267_RS12155	COG2207	Transcriptional regulator
F8267_RS12155	COG3708	Transcriptional regulator
F8267_RS12160	COG3045	CreA protein
F8267_RS12165	COG0745	RESPONSE REGULATOR receiver
F8267_RS12170	COG2205	protein histidine kinase activity
F8267_RS12175	COG4452	Inner membrane protein CreD
F8267_RS12180	COG0745	RESPONSE REGULATOR receiver
F8267_RS12190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F8267_RS12200	COG0460	homoserine dehydrogenase
F8267_RS12200	COG0527	aspartate kinase activity
F8267_RS12210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F8267_RS12220	COG1115	amino acid carrier protein
F8267_RS12225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F8267_RS12230	COG0521	Mo-molybdopterin cofactor biosynthetic process
F8267_RS12235	COG0477	Major facilitator Superfamily
F8267_RS12240	COG1584	GPR1 FUN34 yaaH family protein
F8267_RS12255	COG0583	DNA-binding transcription factor activity
F8267_RS12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F8267_RS12290	COG3539	Fimbrial protein
F8267_RS12300	COG3188	usher protein
F8267_RS12315	COG3539	Fimbrial protein
F8267_RS12320	COG3121	Chaperone
F8267_RS12340	COG0583	DNA-binding transcription factor activity
F8267_RS12355	COG0196	riboflavin kinase activity
F8267_RS12365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F8267_RS12370	COG1047	Peptidyl-prolyl cis-trans
F8267_RS12385	COG0583	DNA-binding transcription factor activity
F8267_RS12390	COG2828	Protein conserved in bacteria
F8267_RS12395	COG0471	metal ion transport
F8267_RS12400	COG0471	metal ion transport
F8267_RS12405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F8267_RS12415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F8267_RS12480	COG0505	Belongs to the CarA family
F8267_RS12530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F8267_RS12540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F8267_RS12545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F8267_RS12560	COG3493	citrate carrier protein
F8267_RS12570	COG0564	pseudouridine synthase activity
F8267_RS12580	COG0417	DNA replication proofreading
F8267_RS12585	COG0235	Class ii aldolase
F8267_RS12605	COG0586	Pfam SNARE associated Golgi protein
F8267_RS12615	COG1178	ABC-type Fe3 transport system permease component
F8267_RS12635	COG2814	Major facilitator Superfamily
F8267_RS12640	COG2271	Major facilitator Superfamily
F8267_RS12645	COG0583	DNA-binding transcription factor activity
F8267_RS12655	COG0738	Major facilitator superfamily
F8267_RS12700	COG0028	Belongs to the TPP enzyme family
F8267_RS12730	COG0768	penicillin binding
F8267_RS12735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F8267_RS12740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F8267_RS12755	COG0772	Belongs to the SEDS family
F8267_RS12770	COG1181	Belongs to the D-alanine--D-alanine ligase family
F8267_RS12780	COG0849	cell division
F8267_RS12785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F8267_RS12805	COG0494	nUDIX hydrolase
F8267_RS12830	COG1459	type II secretion system
F8267_RS12835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F8267_RS12840	COG4969	Belongs to the N-Me-Phe pilin family
F8267_RS12855	COG3725	Membrane protein required for beta-lactamase induction
F8267_RS12860	COG3940	Belongs to the glycosyl hydrolase 43 family
F8267_RS12865	COG2211	Major facilitator Superfamily
F8267_RS12870	COG1113	amino acid transport
F8267_RS12875	COG2186	Transcriptional regulator
F8267_RS12880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F8267_RS12885	COG0508	dehydrogenase complex catalyzes the overall conversion of
F8267_RS12890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F8267_RS12905	COG3064	Membrane
F8267_RS12910	COG1049	propionate catabolic process, 2-methylcitrate cycle
F8267_RS12930	COG0545	Peptidyl-prolyl cis-trans isomerase
F8267_RS12945	COG2132	Multicopper oxidase
F8267_RS12950	COG4993	Dehydrogenase
F8267_RS12960	COG0288	reversible hydration of carbon dioxide
F8267_RS12965	COG1131	(ABC) transporter
F8267_RS12970	COG0842	Transport permease protein
F8267_RS12975	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS12980	COG0726	polysaccharide deacetylase
F8267_RS12985	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F8267_RS13000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F8267_RS13025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F8267_RS13030	COG1643	Atp-dependent helicase
F8267_RS13035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F8267_RS13040	COG4774	siderophore transport
F8267_RS13045	COG1120	ATPase activity
F8267_RS13050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F8267_RS13055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS13075	COG2860	membrane
F8267_RS13080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F8267_RS13100	COG3835	regulator
F8267_RS13120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F8267_RS13125	COG0024	Methionine aminopeptidase
F8267_RS13150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F8267_RS13160	COG0575	Belongs to the CDS family
F8267_RS13165	COG0750	zinc metalloprotease
F8267_RS13225	COG0346	lactoylglutathione lyase activity
F8267_RS13230	COG0037	tRNA processing
F8267_RS13235	COG4568	rho-dependent transcription termination
F8267_RS13250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F8267_RS13255	COG3015	lipoprotein NlpE involved in copper resistance
F8267_RS13265	COG1720	tRNA m6t6A37 methyltransferase activity
F8267_RS13275	COG1464	Belongs to the NlpA lipoprotein family
F8267_RS13280	COG2011	ABC-type metal ion transport system permease component
F8267_RS13290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F8267_RS13325	COG0656	L-ascorbic acid biosynthetic process
F8267_RS13330	COG0583	DNA-binding transcription factor activity
F8267_RS13335	COG2814	Major facilitator Superfamily
F8267_RS13345	COG2226	methyltransferase
F8267_RS13350	COG1388	LysM domain
F8267_RS13350	COG0741	lytic transglycosylase activity
F8267_RS13360	COG2226	methyltransferase
F8267_RS13370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F8267_RS13380	COG0583	DNA-binding transcription factor activity
F8267_RS13390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F8267_RS13395	COG1960	acyl-CoA dehydrogenase activity
F8267_RS13405	COG0121	glutamine amidotransferase
F8267_RS13410	COG3034	peptidoglycan biosynthetic process
F8267_RS13425	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F8267_RS13430	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F8267_RS13445	COG2991	Protein conserved in bacteria
F8267_RS13460	COG0454	-acetyltransferase
F8267_RS13465	COG2195	Cleaves the N-terminal amino acid of tripeptides
F8267_RS13485	COG1045	serine acetyltransferase
F8267_RS13500	COG0297	glycogen (starch) synthase activity
F8267_RS13500	COG0438	transferase activity, transferring glycosyl groups
F8267_RS13505	COG0438	transferase activity, transferring glycosyl groups
F8267_RS13510	COG0463	Glycosyl transferase, family 2
F8267_RS13530	COG1596	polysaccharide export
F8267_RS13540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F8267_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS13565	COG0583	DNA-binding transcription factor activity
F8267_RS13575	COG1802	Transcriptional regulator
F8267_RS13580	COG1113	amino acid transport
F8267_RS13585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F8267_RS13590	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS13595	COG0579	oxidoreductase
F8267_RS13615	COG3188	usher protein
F8267_RS13620	COG3121	Chaperone
F8267_RS13695	COG0791	NLP P60 protein
F8267_RS13715	COG3639	organic phosphonate transmembrane transporter activity
F8267_RS13725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F8267_RS13750	COG3188	usher protein
F8267_RS13770	COG2271	Major facilitator Superfamily
F8267_RS13775	COG0583	DNA-binding transcription factor activity
F8267_RS13780	COG0765	amino acid transport
F8267_RS13785	COG0765	amino acid transport
F8267_RS13795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS13800	COG0833	amino acid
F8267_RS13805	COG2040	homocysteine
F8267_RS13810	COG4521	taurine ABC transporter
F8267_RS13815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F8267_RS13820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F8267_RS13825	COG2175	clavaminate synthase activity
F8267_RS13840	COG1943	Transposase
F8267_RS13845	COG0113	porphobilinogen synthase activity
F8267_RS13850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F8267_RS13860	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F8267_RS13895	COG1785	Belongs to the alkaline phosphatase family
F8267_RS13905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F8267_RS13915	COG3416	Protein conserved in bacteria
F8267_RS13920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F8267_RS13930	COG4126	flavin adenine dinucleotide binding
F8267_RS13945	COG1940	carbohydrate kinase activity
F8267_RS13950	COG0419	ATPase involved in DNA repair
F8267_RS13955	COG0420	3'-5' exonuclease activity
F8267_RS13980	COG0366	Alpha amylase catalytic
F8267_RS13985	COG0583	DNA-binding transcription factor activity
F8267_RS13990	COG1335	isochorismatase
F8267_RS14000	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F8267_RS14005	COG0450	alkyl hydroperoxide reductase
F8267_RS14025	COG1862	Preprotein translocase
F8267_RS14035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F8267_RS14050	COG3248	Nucleoside-binding outer membrane protein
F8267_RS14055	COG4238	major outer membrane lipoprotein
F8267_RS14065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F8267_RS14065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F8267_RS14080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F8267_RS14085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F8267_RS14090	COG0667	Aldo Keto reductase
F8267_RS14100	COG0142	geranyltranstransferase activity
F8267_RS14125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F8267_RS14140	COG2831	hemolysin activation secretion protein
F8267_RS14145	COG0736	holo-[acyl-carrier-protein] synthase activity
F8267_RS14155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F8267_RS14160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F8267_RS14170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F8267_RS14185	COG1136	(ABC) transporter
F8267_RS14195	COG2177	Part of the ABC transporter FtsEX involved in
F8267_RS14225	COG2814	Major facilitator Superfamily
F8267_RS14240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F8267_RS14245	COG1845	cytochrome c oxidase, subunit III
F8267_RS14250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F8267_RS14255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F8267_RS14260	COG2223	nitrite transmembrane transporter activity
F8267_RS14265	COG3056	Lipoprotein
F8267_RS14270	COG0271	Belongs to the BolA IbaG family
F8267_RS14290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F8267_RS14295	COG0776	regulation of translation
F8267_RS14300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F8267_RS14305	COG1555	photosystem II stabilization
F8267_RS14310	COG0824	Thioesterase
F8267_RS14320	COG4533	DNA binding
F8267_RS14335	COG1522	sequence-specific DNA binding
F8267_RS14340	COG1132	(ABC) transporter
F8267_RS14345	COG1132	(ABC) transporter
F8267_RS14350	COG0347	Belongs to the P(II) protein family
F8267_RS14355	COG0004	ammonium transporteR
F8267_RS14360	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F8267_RS14365	COG0583	DNA-binding transcription factor activity
F8267_RS14370	COG1946	Acyl-CoA thioesterase
F8267_RS14375	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F8267_RS14380	COG3695	enzyme binding
F8267_RS14410	COG2364	Membrane
F8267_RS14415	COG5507	3-demethylubiquinone-9 3-methyltransferase
F8267_RS14420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F8267_RS14430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F8267_RS14450	COG0110	maltose O-acetyltransferase activity
F8267_RS14465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F8267_RS14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS14475	COG1309	transcriptional regulator
F8267_RS14480	COG1196	nuclear chromosome segregation
F8267_RS14480	COG3264	Mechanosensitive ion channel
F8267_RS14490	COG3923	Primosomal replication protein n
F8267_RS14495	COG2832	Protein of unknown function (DUF454)
F8267_RS14535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F8267_RS14540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F8267_RS14540	COG4651	solute:proton antiporter activity
F8267_RS14545	COG2223	nitrite transmembrane transporter activity
F8267_RS14555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F8267_RS14560	COG3735	TraB family
F8267_RS14575	COG1585	Membrane protein implicated in regulation of membrane protease activity
F8267_RS14580	COG0330	HflC and HflK could
F8267_RS14585	COG4619	ABC transporter
F8267_RS14590	COG0390	transport system, permease component
F8267_RS14595	COG3118	belongs to the thioredoxin family
F8267_RS14600	COG0300	oxidoreductase activity
F8267_RS14605	COG2755	lipolytic protein G-D-S-L family
F8267_RS14610	COG4181	ATPase activity
F8267_RS14615	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F8267_RS14630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F8267_RS14635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F8267_RS14645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F8267_RS14655	COG2501	S4 domain
F8267_RS14695	COG0583	DNA-binding transcription factor activity
F8267_RS14710	COG1560	Kdo2-lipid A biosynthetic process
F8267_RS14720	COG1902	pentaerythritol trinitrate reductase activity
F8267_RS14725	COG3710	Transcriptional regulator
F8267_RS14730	COG0531	amino acid
F8267_RS14735	COG1982	Orn Lys Arg decarboxylase major
F8267_RS14740	COG3104	oligopeptide transport
F8267_RS14750	COG0402	S-adenosylhomocysteine deaminase activity
F8267_RS14755	COG0549	Belongs to the carbamate kinase family
F8267_RS14760	COG1304	FMN binding
F8267_RS14765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F8267_RS14775	COG0666	response to abiotic stimulus
F8267_RS14785	COG0583	DNA-binding transcription factor activity
F8267_RS14800	COG1566	PFAM secretion protein HlyD family protein
F8267_RS14820	COG1473	amidohydrolase
F8267_RS14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS14830	COG0667	Aldo Keto reductase
F8267_RS14875	COG0531	amino acid
F8267_RS14885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F8267_RS14890	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS14895	COG1252	NADH dehydrogenase
F8267_RS14910	COG1113	amino acid transport
F8267_RS14915	COG0668	transmembrane transport
F8267_RS14920	COG0477	Major facilitator Superfamily
F8267_RS14935	COG0778	Nitroreductase
F8267_RS14940	COG2315	Protein conserved in bacteria
F8267_RS14970	COG3698	Phosphodiester glycosidase
F8267_RS14995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F8267_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS15025	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS15030	COG1129	ABC transporter
F8267_RS15040	COG1879	ABC-type sugar transport system periplasmic component
F8267_RS15045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F8267_RS15050	COG2390	Transcriptional regulator
F8267_RS15055	COG3959	Transketolase, thiamine diphosphate binding domain
F8267_RS15060	COG3958	Transketolase
F8267_RS15065	COG4771	TonB-dependent receptor
F8267_RS15070	COG2382	esterase
F8267_RS15075	COG3251	PFAM MbtH domain protein
F8267_RS15080	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F8267_RS15080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F8267_RS15085	COG1120	ATPase activity
F8267_RS15090	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS15095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS15110	COG4592	Periplasmic binding protein
F8267_RS15115	COG1169	isochorismate synthase
F8267_RS15120	COG1021	2,3-dihydroxybenzoate-AMP ligase
F8267_RS15125	COG3433	isochorismatase activity
F8267_RS15125	COG1535	isochorismatase
F8267_RS15130	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS15140	COG1966	Carbon starvation protein
F8267_RS15145	COG2879	small protein
F8267_RS15165	COG1129	ABC transporter
F8267_RS15170	COG1172	Belongs to the binding-protein-dependent transport system permease family
F8267_RS15195	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
F8267_RS15205	COG0436	Aminotransferase
F8267_RS15210	COG1475	DNA binding
F8267_RS15215	COG3969	phosphoadenosine phosphosulfate
F8267_RS15220	COG0583	DNA-binding transcription factor activity
F8267_RS15225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F8267_RS15235	COG3634	alkyl hydroperoxide reductase activity
F8267_RS15245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F8267_RS15250	COG3719	Belongs to the RNase T2 family
F8267_RS15255	COG3069	C4-dicarboxylate transmembrane transporter activity
F8267_RS15275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F8267_RS15290	COG0583	DNA-binding transcription factor activity
F8267_RS15305	COG1686	Belongs to the peptidase S11 family
F8267_RS15310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F8267_RS15315	COG0772	Belongs to the SEDS family
F8267_RS15320	COG0768	penicillin binding
F8267_RS15330	COG0799	negative regulation of ribosome biogenesis
F8267_RS15335	COG0406	alpha-ribazole phosphatase activity
F8267_RS15345	COG1466	dna polymerase III delta subunit
F8267_RS15360	COG2888	peptidyl-tyrosine sulfation
F8267_RS15370	COG2831	hemolysin activation secretion protein
F8267_RS15375	COG1126	abc transporter atp-binding protein
F8267_RS15380	COG0765	amino acid transport
F8267_RS15385	COG0765	amino acid transport
F8267_RS15410	COG1702	phosphate starvation-inducible protein PhoH
F8267_RS15420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F8267_RS15460	COG0367	asparagine synthase
F8267_RS15465	COG0647	UMP catabolic process
F8267_RS15470	COG1846	Transcriptional regulator
F8267_RS15470	COG1940	carbohydrate kinase activity
F8267_RS15475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F8267_RS15520	COG1053	succinate dehydrogenase
F8267_RS15525	COG0583	DNA-binding transcription factor activity
F8267_RS15530	COG0735	belongs to the Fur family
F8267_RS15545	COG0596	Alpha beta hydrolase
F8267_RS15555	COG0033	Phosphoglucomutase
F8267_RS15560	COG0745	RESPONSE REGULATOR receiver
F8267_RS15565	COG2205	protein histidine kinase activity
F8267_RS15595	COG0415	Belongs to the DNA photolyase family
F8267_RS15605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F8267_RS15610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F8267_RS15615	COG1984	allophanate hydrolase subunit 2
F8267_RS15645	COG0372	Belongs to the citrate synthase family
F8267_RS15650	COG2009	succinate dehydrogenase
F8267_RS15655	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F8267_RS15660	COG1053	succinate dehydrogenase
F8267_RS15665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F8267_RS15670	COG0567	Dehydrogenase, E1 component
F8267_RS15675	COG0508	dehydrogenase complex catalyzes the overall conversion of
F8267_RS15685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F8267_RS15690	COG1271	oxidase subunit
F8267_RS15695	COG1294	oxidase, subunit
F8267_RS15700	COG4890	Cyd operon protein YbgT
F8267_RS15705	COG3790	cyd operon protein YbgE
F8267_RS15710	COG0824	Thioesterase
F8267_RS15715	COG0811	peptide transport
F8267_RS15720	COG0848	biopolymer transport protein
F8267_RS15725	COG3064	Membrane
F8267_RS15735	COG2885	chlorophyll binding
F8267_RS15740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F8267_RS15780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F8267_RS15790	COG1230	cation diffusion facilitator family transporter
F8267_RS15800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F8267_RS15810	COG2017	converts alpha-aldose to the beta-anomer
F8267_RS15820	COG1085	galactose-1-phosphate uridylyltransferase
F8267_RS15825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F8267_RS15830	COG1119	ATPase activity
F8267_RS15835	COG3585	molybdate ion transport
F8267_RS15835	COG2005	Transcriptional regulator
F8267_RS15845	COG0725	ABC transporter, periplasmic molybdate-binding protein
F8267_RS15850	COG4149	molybdate abc transporter
F8267_RS15860	COG0561	phosphatase activity
F8267_RS15885	COG2200	EAL domain
F8267_RS15890	COG0789	Transcriptional regulator
F8267_RS15915	COG1595	DNA-templated transcription, initiation
F8267_RS15925	COG4677	pectinesterase activity
F8267_RS15965	COG1881	PFAM PEBP family protein
F8267_RS15970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F8267_RS15985	COG2226	methyltransferase
F8267_RS16000	COG0642	Histidine kinase
F8267_RS16005	COG0745	RESPONSE REGULATOR receiver
F8267_RS16025	COG0521	Mo-molybdopterin cofactor biosynthetic process
F8267_RS16035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F8267_RS16040	COG0314	molybdopterin synthase activity
F8267_RS16045	COG0670	Belongs to the BI1 family
F8267_RS16050	COG0392	lysyltransferase activity
F8267_RS16055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F8267_RS16060	COG3568	Endonuclease Exonuclease Phosphatase
F8267_RS16070	COG0842	Transport permease protein
F8267_RS16075	COG0842	Transport permease protein
F8267_RS16080	COG1131	(ABC) transporter
F8267_RS16090	COG1309	transcriptional regulator
F8267_RS16095	COG0513	Belongs to the DEAD box helicase family
F8267_RS16110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F8267_RS16120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F8267_RS16130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F8267_RS16140	COG0668	transmembrane transport
F8267_RS16145	COG1126	abc transporter atp-binding protein
F8267_RS16150	COG0765	amino acid transport
F8267_RS16155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS16170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F8267_RS16175	COG2194	sulfuric ester hydrolase activity
F8267_RS16185	COG1321	iron dependent repressor
F8267_RS16190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F8267_RS16195	COG0667	Aldo Keto reductase
F8267_RS16200	COG2723	6-phospho-beta-galactosidase activity
F8267_RS16205	COG2188	Transcriptional regulator
F8267_RS16210	COG1376	ErfK ybiS ycfS ynhG family protein
F8267_RS16220	COG0488	(ABC) transporter
F8267_RS16230	COG2271	Major facilitator Superfamily
F8267_RS16235	COG1609	Transcriptional regulator
F8267_RS16245	COG0561	phosphatase activity
F8267_RS16250	COG1882	Formate acetyltransferase
F8267_RS16255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F8267_RS16260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F8267_RS16265	COG0303	'Molybdopterin
F8267_RS16270	COG1446	asparaginase
F8267_RS16280	COG0747	negative chemotaxis
F8267_RS16305	COG2133	pyrroloquinoline quinone binding
F8267_RS16310	COG0625	glutathione transferase activity
F8267_RS16315	COG1686	Belongs to the peptidase S11 family
F8267_RS16320	COG1349	DNA-binding transcription factor activity
F8267_RS16325	COG0671	phosphoesterase, PA-phosphatase related
F8267_RS16330	COG2814	Major facilitator Superfamily
F8267_RS16335	COG0561	phosphatase activity
F8267_RS16340	COG0738	Major facilitator superfamily
F8267_RS16345	COG3226	Transcriptional regulator
F8267_RS16350	COG0300	oxidoreductase activity
F8267_RS16390	COG0778	Nitroreductase
F8267_RS16405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F8267_RS16410	COG3842	ATPase activity
F8267_RS16415	COG1176	ABC-type spermidine putrescine transport system, permease component I
F8267_RS16420	COG1177	transmembrane transport
F8267_RS16430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F8267_RS16435	COG0745	RESPONSE REGULATOR receiver
F8267_RS16440	COG5002	protein histidine kinase activity
F8267_RS16445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS16450	COG4160	amino acid transport
F8267_RS16455	COG4215	(ABC) transporter
F8267_RS16460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F8267_RS16465	COG1126	abc transporter atp-binding protein
F8267_RS16475	COG2067	long-chain fatty acid transport protein
F8267_RS16485	COG5001	Diguanylate cyclase
F8267_RS16485	COG4251	negative regulation of phosphorylation
F8267_RS16485	COG3706	GGDEF domain
F8267_RS16485	COG2203	Gaf domain
F8267_RS16490	COG3023	N-Acetylmuramoyl-L-alanine amidase
F8267_RS16495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F8267_RS16500	COG0702	epimerase
F8267_RS16505	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F8267_RS16510	COG0028	Belongs to the TPP enzyme family
F8267_RS16520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F8267_RS16530	COG2431	L-lysine efflux transmembrane transporter activity
F8267_RS16540	COG3593	DNA synthesis involved in DNA repair
F8267_RS16545	COG2990	Protein conserved in bacteria
F8267_RS16550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS16560	COG1278	Cold shock
F8267_RS16570	COG0542	response to heat
F8267_RS16590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F8267_RS16595	COG4988	ABC transporter
F8267_RS16600	COG0492	ferredoxin-NADP+ reductase activity
F8267_RS16620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F8267_RS16630	COG0243	molybdopterin cofactor binding
F8267_RS16635	COG0437	4 iron, 4 sulfur cluster binding
F8267_RS16640	COG3302	dmso reductase anchor subunit
F8267_RS16645	COG0477	Major facilitator Superfamily
F8267_RS16650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F8267_RS16655	COG1882	Formate acetyltransferase
F8267_RS16660	COG2116	formate transmembrane transporter activity
F8267_RS16665	COG1944	ATP diphosphatase activity
F8267_RS16690	COG0539	negative regulation of cytoplasmic translation
F8267_RS16700	COG0658	competence protein
F8267_RS16700	COG2333	competence protein COMEC
F8267_RS16705	COG1132	(ABC) transporter
F8267_RS16715	COG3214	Protein conserved in bacteria
F8267_RS16720	COG2835	tetraacyldisaccharide 4'-kinase activity
F8267_RS16730	COG3173	Aminoglycoside phosphotransferase
F8267_RS16735	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F8267_RS16740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F8267_RS16750	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F8267_RS16760	COG2989	Protein conserved in bacteria
F8267_RS16765	COG3108	Peptidase M15
F8267_RS16770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F8267_RS16775	COG1448	Aminotransferase
F8267_RS16780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F8267_RS16795	COG0308	aminopeptidase N
F8267_RS16805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F8267_RS16810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS16815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F8267_RS16820	COG0431	NADPH-dependent FMN reductase
F8267_RS16835	COG3217	Mosc domain protein beta barrel domain protein
F8267_RS16835	COG0633	Ferredoxin
F8267_RS16845	COG0488	(ABC) transporter
F8267_RS16850	COG2995	paraquat-inducible protein a
F8267_RS16855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F8267_RS16855	COG3008	intermembrane lipid transfer
F8267_RS16860	COG3009	Protein conserved in bacteria
F8267_RS16865	COG3130	regulation of translation
F8267_RS16875	COG1067	ATP-dependent peptidase activity
F8267_RS16895	COG3070	regulator of competence-specific genes
F8267_RS16900	COG1289	transmembrane transporter activity
F8267_RS16905	COG3304	Inner membrane component domain
F8267_RS16910	COG0210	DNA helicase
F8267_RS16920	COG1832	CoA-binding protein
F8267_RS16935	COG2274	protein secretion by the type I secretion system
F8267_RS16940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS16945	COG0438	transferase activity, transferring glycosyl groups
F8267_RS16975	COG0670	Belongs to the BI1 family
F8267_RS16990	COG0583	DNA-binding transcription factor activity
F8267_RS17005	COG0583	DNA-binding transcription factor activity
F8267_RS17060	COG2198	Histidine kinase
F8267_RS17060	COG0643	Histidine kinase
F8267_RS17065	COG0835	chemotaxis
F8267_RS17070	COG0840	transmembrane signaling receptor activity
F8267_RS17075	COG0840	transmembrane signaling receptor activity
F8267_RS17080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F8267_RS17090	COG0745	RESPONSE REGULATOR receiver
F8267_RS17095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F8267_RS17100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F8267_RS17105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F8267_RS17115	COG3418	PFAM FlgN family protein
F8267_RS17120	COG2747	anti-sigma28 factor FlgM
F8267_RS17130	COG1815	bacterial-type flagellum-dependent cell motility
F8267_RS17135	COG1558	bacterial-type flagellum-dependent cell motility
F8267_RS17140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F8267_RS17155	COG4786	Flagellar basal body rod
F8267_RS17175	COG1256	bacterial-type flagellum assembly
F8267_RS17210	COG2814	Major facilitator Superfamily
F8267_RS17220	COG1414	Transcriptional regulator
F8267_RS17225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F8267_RS17230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F8267_RS17295	COG2882	bacterial-type flagellum organization
F8267_RS17300	COG1157	protein secretion by the type III secretion system
F8267_RS17310	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F8267_RS17320	COG1677	Flagellar hook-basal body complex protein FliE
F8267_RS17360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F8267_RS17375	COG1191	sigma factor activity
F8267_RS17415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F8267_RS17420	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS17425	COG4638	Rieske (2fe-2S)
F8267_RS17430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F8267_RS17435	COG0473	3-isopropylmalate dehydrogenase activity
F8267_RS17440	COG0583	DNA-binding transcription factor activity
F8267_RS17445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F8267_RS17450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F8267_RS17455	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS17460	COG1396	sequence-specific DNA binding
F8267_RS17460	COG1917	Cupin 2, conserved barrel domain protein
F8267_RS17465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F8267_RS17470	COG0174	glutamine synthetase
F8267_RS17475	COG0531	amino acid
F8267_RS17540	COG3729	General stress protein
F8267_RS17550	COG2233	PERMEase
F8267_RS17585	COG1309	transcriptional regulator
F8267_RS17600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F8267_RS17605	COG0628	permease
F8267_RS17615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F8267_RS17625	COG2822	iron ion transport
F8267_RS17635	COG1702	phosphate starvation-inducible protein PhoH
F8267_RS17650	COG1335	isochorismatase
F8267_RS17660	COG0583	DNA-binding transcription factor activity
F8267_RS17680	COG3381	protein complex oligomerization
F8267_RS17720	COG5645	(Lipo)protein
F8267_RS17735	COG1560	Kdo2-lipid A biosynthetic process
F8267_RS17780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F8267_RS17790	COG0673	inositol 2-dehydrogenase activity
F8267_RS17800	COG2814	Major facilitator Superfamily
F8267_RS17805	COG0583	DNA-binding transcription factor activity
F8267_RS17825	COG1399	metal-binding, possibly nucleic acid-binding protein
F8267_RS17845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F8267_RS17850	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS17860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F8267_RS17865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F8267_RS17870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F8267_RS17880	COG0470	DNA polymerase III
F8267_RS17885	COG0084	hydrolase, TatD family'
F8267_RS17890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS17890	COG1263	PTS System
F8267_RS17895	COG0537	adenosine 5'-monophosphoramidase activity
F8267_RS17900	COG5633	Lipoprotein
F8267_RS17925	COG1252	NADH dehydrogenase
F8267_RS17930	COG3134	Outer membrane lipoprotein
F8267_RS17940	COG1309	transcriptional regulator
F8267_RS17950	COG1376	ErfK ybiS ycfS ynhG family protein
F8267_RS17950	COG1388	LysM domain
F8267_RS17955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F8267_RS17960	COG4591	ABC-type transport system involved in lipoprotein release permease component
F8267_RS17965	COG1136	(ABC) transporter
F8267_RS17970	COG4591	ABC-type transport system involved in lipoprotein release permease component
F8267_RS17980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F8267_RS17985	COG0318	PFAM AMP-dependent synthetase and ligase
F8267_RS17995	COG1177	transmembrane transport
F8267_RS18015	COG1943	Transposase
F8267_RS18020	COG2850	peptidyl-arginine hydroxylation
F8267_RS18035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F8267_RS18055	COG1187	pseudouridine synthase activity
F8267_RS18060	COG0538	isocitrate dehydrogenase activity
F8267_RS18070	COG1403	HNH endonuclease
F8267_RS18075	COG3272	Protein of unknown function (DUF1722)
F8267_RS18080	COG0789	Transcriptional regulator
F8267_RS18090	COG4977	sequence-specific DNA binding
F8267_RS18095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F8267_RS18120	COG3122	Protein conserved in bacteria
F8267_RS18130	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F8267_RS18135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS18140	COG3477	response to acidic pH
F8267_RS18145	COG0012	GTP binding
F8267_RS18160	COG0659	secondary active sulfate transmembrane transporter activity
F8267_RS18190	COG2890	protein-(glutamine-N5) methyltransferase activity
F8267_RS18210	COG0387	Pfam Sodium calcium exchanger
F8267_RS18215	COG4572	Cation transport regulator
F8267_RS18220	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F8267_RS18230	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F8267_RS18235	COG3707	response regulator
F8267_RS18240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F8267_RS18250	COG1116	anion transmembrane transporter activity
F8267_RS18260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F8267_RS18260	COG2146	nitrite reductase [NAD(P)H] activity
F8267_RS18265	COG0243	molybdopterin cofactor binding
F8267_RS18270	COG4932	domain protein
F8267_RS18275	COG2197	response regulator
F8267_RS18280	COG3850	Histidine kinase
F8267_RS18285	COG2223	nitrite transmembrane transporter activity
F8267_RS18290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F8267_RS18295	COG1140	nitrate reductase beta subunit
F8267_RS18300	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F8267_RS18305	COG2181	nitrate reductase activity
F8267_RS18315	COG1522	sequence-specific DNA binding
F8267_RS18355	COG0788	formyltetrahydrofolate deformylase activity
F8267_RS18365	COG1752	Esterase of the alpha-beta hydrolase superfamily
F8267_RS18370	COG0745	RESPONSE REGULATOR receiver
F8267_RS18375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F8267_RS18390	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS18390	COG1454	alcohol dehydrogenase
F8267_RS18395	COG2095	MarC family integral membrane protein
F8267_RS18405	COG0601	transmembrane transport
F8267_RS18410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F8267_RS18415	COG0444	Belongs to the ABC transporter superfamily
F8267_RS18425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F8267_RS18450	COG1917	Cupin 2, conserved barrel domain protein
F8267_RS18455	COG0823	Involved in the tonB-independent uptake of proteins
F8267_RS18495	COG2135	peptidase activity
F8267_RS18500	COG2350	Protein conserved in bacteria
F8267_RS18505	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F8267_RS18510	COG3001	Fructosamine kinase
F8267_RS18520	COG1105	Belongs to the carbohydrate kinase PfkB family
F8267_RS18525	COG3137	Salt-induced outer membrane protein
F8267_RS18580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F8267_RS18590	COG0072	phenylalanine-tRNA ligase activity
F8267_RS18590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F8267_RS18610	COG0583	DNA-binding transcription factor activity
F8267_RS18630	COG0386	Belongs to the glutathione peroxidase family
F8267_RS18640	COG0791	NLP P60 protein
F8267_RS18650	COG4256	Hemin uptake protein
F8267_RS18655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F8267_RS18665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F8267_RS18665	COG0574	Belongs to the PEP-utilizing enzyme family
F8267_RS18675	COG0628	permease
F8267_RS18680	COG0277	FAD linked oxidase domain protein
F8267_RS18680	COG0247	lactate metabolic process
F8267_RS18685	COG2050	protein possibly involved in aromatic compounds catabolism
F8267_RS18690	COG3422	double-strand break repair
F8267_RS18695	COG2261	transglycosylase associated protein
F8267_RS18705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F8267_RS18710	COG0316	Belongs to the HesB IscA family
F8267_RS18715	COG0719	Fe-S assembly protein
F8267_RS18720	COG0396	ATPase activity
F8267_RS18725	COG0719	Fe-S assembly protein
F8267_RS18740	COG1376	ErfK ybiS ycfS ynhG family protein
F8267_RS18775	COG2271	Major facilitator Superfamily
F8267_RS18780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F8267_RS18825	COG0583	DNA-binding transcription factor activity
F8267_RS18830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS18850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F8267_RS18855	COG1116	anion transmembrane transporter activity
F8267_RS18860	COG4774	siderophore transport
F8267_RS18865	COG1120	ATPase activity
F8267_RS18870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS18875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS18895	COG0765	amino acid transport
F8267_RS18900	COG1126	abc transporter atp-binding protein
F8267_RS18920	COG1683	Conserved Protein
F8267_RS18945	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS18950	COG2378	regulation of single-species biofilm formation
F8267_RS18970	COG1280	lysine exporter protein (LysE YggA)
F8267_RS18980	COG3590	peptidase
F8267_RS18990	COG2207	Transcriptional regulator
F8267_RS19000	COG0251	oxidation-reduction process
F8267_RS19005	COG1309	transcriptional regulator
F8267_RS19025	COG0406	alpha-ribazole phosphatase activity
F8267_RS19030	COG1396	sequence-specific DNA binding
F8267_RS19035	COG0456	acetyltransferase
F8267_RS19050	COG3383	formate dehydrogenase (NAD+) activity
F8267_RS19055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F8267_RS19070	COG1175	transmembrane transport
F8267_RS19100	COG1138	Cytochrome C-type biogenesis protein
F8267_RS19125	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS19130	COG2610	gluconate transmembrane transporter activity
F8267_RS19135	COG1250	3-hydroxyacyl-CoA dehydrogenase
F8267_RS19145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F8267_RS19155	COG0583	DNA-binding transcription factor activity
F8267_RS19165	COG4993	Dehydrogenase
F8267_RS19175	COG4608	Belongs to the ABC transporter superfamily
F8267_RS19180	COG0444	Belongs to the ABC transporter superfamily
F8267_RS19205	COG0346	lactoylglutathione lyase activity
F8267_RS19210	COG1349	DNA-binding transcription factor activity
F8267_RS19230	COG2233	PERMEase
F8267_RS19240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS19245	COG0402	S-adenosylhomocysteine deaminase activity
F8267_RS19250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F8267_RS19250	COG0493	'glutamate synthase
F8267_RS19255	COG2068	MobA-Related Protein
F8267_RS19260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F8267_RS19265	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F8267_RS19265	COG3608	succinylglutamate desuccinylase aspartoacylase
F8267_RS19270	COG0549	Belongs to the carbamate kinase family
F8267_RS19280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F8267_RS19285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F8267_RS19290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F8267_RS19300	COG2223	nitrite transmembrane transporter activity
F8267_RS19360	COG0534	Mate efflux family protein
F8267_RS19365	COG0307	riboflavin synthase, alpha
F8267_RS19370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F8267_RS19375	COG2814	Major facilitator Superfamily
F8267_RS19380	COG0583	DNA-binding transcription factor activity
F8267_RS19395	COG2814	Major facilitator Superfamily
F8267_RS19405	COG3708	Transcriptional regulator
F8267_RS19405	COG2207	Transcriptional regulator
F8267_RS19410	COG0791	NLP P60 protein
F8267_RS19415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F8267_RS19425	COG0346	lactoylglutathione lyase activity
F8267_RS19430	COG1902	pentaerythritol trinitrate reductase activity
F8267_RS19435	COG1309	transcriptional regulator
F8267_RS19440	COG3313	Fe-S protein
F8267_RS19445	COG4989	oxidoreductase activity
F8267_RS19450	COG2032	superoxide dismutase activity
F8267_RS19455	COG1289	transmembrane transporter activity
F8267_RS19460	COG1566	PFAM secretion protein HlyD family protein
F8267_RS19475	COG3706	GGDEF domain
F8267_RS19490	COG3895	Periplasmic Protein
F8267_RS19505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F8267_RS19510	COG0625	glutathione transferase activity
F8267_RS19520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F8267_RS19530	COG4659	FMN binding
F8267_RS19565	COG2723	6-phospho-beta-galactosidase activity
F8267_RS19575	COG0673	inositol 2-dehydrogenase activity
F8267_RS19585	COG5562	phage envelope protein
F8267_RS19595	COG0789	Transcriptional regulator
F8267_RS19605	COG0425	Belongs to the sulfur carrier protein TusA family
F8267_RS19610	COG2391	methyltransferase activity
F8267_RS19620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F8267_RS19625	COG1263	PTS System
F8267_RS19625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS19630	COG1609	Transcriptional regulator
F8267_RS19635	COG5339	Protein conserved in bacteria
F8267_RS19640	COG1482	cell wall glycoprotein biosynthetic process
F8267_RS19645	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F8267_RS19645	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F8267_RS19660	COG2205	protein histidine kinase activity
F8267_RS19670	COG0745	RESPONSE REGULATOR receiver
F8267_RS19675	COG3136	membrane protein required for alginate biosynthesis
F8267_RS19685	COG0531	amino acid
F8267_RS19700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F8267_RS19705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F8267_RS19720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F8267_RS19725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F8267_RS19730	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F8267_RS19735	COG1473	amidohydrolase
F8267_RS19745	COG0583	DNA-binding transcription factor activity
F8267_RS19750	COG2840	Smr protein MutS2
F8267_RS19755	COG1414	Transcriptional regulator
F8267_RS19765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F8267_RS19770	COG0183	Belongs to the thiolase family
F8267_RS19780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F8267_RS19785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F8267_RS19815	COG4565	transcriptional regulatory protein
F8267_RS19820	COG3290	protein histidine kinase activity
F8267_RS19825	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F8267_RS19840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F8267_RS19850	COG0679	Auxin Efflux Carrier
F8267_RS19880	COG0628	permease
F8267_RS19895	COG3300	MHYT domain
F8267_RS19895	COG5001	Diguanylate cyclase
F8267_RS19900	COG3591	Belongs to the peptidase S1B family
F8267_RS19915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F8267_RS19920	COG2814	Major facilitator Superfamily
F8267_RS19925	COG0583	DNA-binding transcription factor activity
F8267_RS19930	COG1940	carbohydrate kinase activity
F8267_RS19935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F8267_RS19950	COG3302	dmso reductase anchor subunit
F8267_RS19955	COG0437	4 iron, 4 sulfur cluster binding
F8267_RS19960	COG0243	molybdopterin cofactor binding
F8267_RS19975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F8267_RS19990	COG2271	Major facilitator Superfamily
F8267_RS19995	COG4948	Mandelate Racemase Muconate Lactonizing
F8267_RS20000	COG1063	alcohol dehydrogenase
F8267_RS20005	COG0477	Major facilitator Superfamily
F8267_RS20010	COG0246	Mannitol dehydrogenase
F8267_RS20020	COG1802	Transcriptional regulator
F8267_RS20025	COG4221	oxidoreductase activity
F8267_RS20040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F8267_RS20045	COG2223	nitrite transmembrane transporter activity
F8267_RS20070	COG2203	Gaf domain
F8267_RS20070	COG2199	diguanylate cyclase activity
F8267_RS20080	COG0583	DNA-binding transcription factor activity
F8267_RS20105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F8267_RS20115	COG2814	Major facilitator Superfamily
F8267_RS20120	COG0697	spore germination
F8267_RS20135	COG1846	Transcriptional regulator
F8267_RS20155	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS20175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F8267_RS20185	COG3395	kinase activity
F8267_RS20190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F8267_RS20195	COG1349	DNA-binding transcription factor activity
F8267_RS20200	COG0583	DNA-binding transcription factor activity
F8267_RS20205	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS20220	COG2199	diguanylate cyclase activity
F8267_RS20240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F8267_RS20245	COG2271	Major facilitator Superfamily
F8267_RS20250	COG3622	Belongs to the hyi family
F8267_RS20255	COG0235	Class ii aldolase
F8267_RS20260	COG3395	kinase activity
F8267_RS20265	COG1349	DNA-binding transcription factor activity
F8267_RS20295	COG0697	spore germination
F8267_RS20300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F8267_RS20305	COG0477	Major facilitator Superfamily
F8267_RS20315	COG2070	2-Nitropropane dioxygenase
F8267_RS20320	COG2011	ABC-type metal ion transport system permease component
F8267_RS20340	COG4628	conserved protein (DUF2132)
F8267_RS20345	COG2207	Transcriptional regulator
F8267_RS20370	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS20375	COG3729	General stress protein
F8267_RS20380	COG3685	Protein conserved in bacteria
F8267_RS20390	COG3685	Protein conserved in bacteria
F8267_RS20395	COG1271	oxidase subunit
F8267_RS20400	COG1294	oxidase, subunit
F8267_RS20420	COG2323	membrane
F8267_RS20430	COG3111	PFAM Bacterial OB fold (BOF) protein
F8267_RS20435	COG0626	cystathionine gamma-synthase activity
F8267_RS20450	COG2610	gluconate transmembrane transporter activity
F8267_RS20455	COG1312	Catalyzes the dehydration of D-mannonate
F8267_RS20460	COG0401	homolog of Blt101
F8267_RS20470	COG4529	Protein conserved in bacteria
F8267_RS20485	COG2814	Major facilitator Superfamily
F8267_RS20500	COG4191	Histidine kinase
F8267_RS20500	COG2205	protein histidine kinase activity
F8267_RS20500	COG0745	RESPONSE REGULATOR receiver
F8267_RS20510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F8267_RS20515	COG0588	phosphoglycerate mutase activity
F8267_RS20665	COG0583	DNA-binding transcription factor activity
F8267_RS20670	COG2814	Major facilitator Superfamily
F8267_RS20680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F8267_RS20745	COG1953	Uracil, thiamine, allantoin
F8267_RS20750	COG0402	S-adenosylhomocysteine deaminase activity
F8267_RS20755	COG2351	hydroxyisourate hydrolase activity
F8267_RS20765	COG2233	PERMEase
F8267_RS20770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F8267_RS20800	COG0454	-acetyltransferase
F8267_RS20805	COG0668	transmembrane transport
F8267_RS20885	COG3501	Rhs element vgr protein
F8267_RS20900	COG0515	serine threonine protein kinase
F8267_RS20900	COG2815	serine threonine protein kinase
F8267_RS21040	COG2070	2-Nitropropane dioxygenase
F8267_RS21045	COG0583	DNA-binding transcription factor activity
F8267_RS21080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F8267_RS21085	COG1116	anion transmembrane transporter activity
F8267_RS21090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F8267_RS21095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F8267_RS21100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F8267_RS21105	COG0076	glutamate decarboxylase activity
F8267_RS21115	COG2205	protein histidine kinase activity
F8267_RS21120	COG0745	RESPONSE REGULATOR receiver
F8267_RS21185	COG0583	DNA-binding transcription factor activity
F8267_RS21195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F8267_RS21200	COG1309	transcriptional regulator
F8267_RS21225	COG2814	Major facilitator Superfamily
F8267_RS21235	COG0583	DNA-binding transcription factor activity
F8267_RS21245	COG0243	molybdopterin cofactor binding
F8267_RS21250	COG1271	oxidase subunit
F8267_RS21255	COG1294	oxidase, subunit
F8267_RS21265	COG3781	membrane
F8267_RS21270	COG2837	iron assimilation
F8267_RS21285	COG1764	response to oxidative stress
F8267_RS21310	COG1609	Transcriptional regulator
F8267_RS21330	COG0488	(ABC) transporter
F8267_RS21340	COG1064	alcohol dehydrogenase
F8267_RS21345	COG0747	negative chemotaxis
F8267_RS21365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS21375	COG2814	Major facilitator Superfamily
F8267_RS21435	COG2864	formate dehydrogenase
F8267_RS21440	COG0437	4 iron, 4 sulfur cluster binding
F8267_RS21450	COG0697	spore germination
F8267_RS21465	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F8267_RS21475	COG3485	protocatechuate 3,4-dioxygenase
F8267_RS21480	COG4829	muconolactone delta-isomerase
F8267_RS21485	COG4948	Mandelate Racemase Muconate Lactonizing
F8267_RS21490	COG1414	Transcriptional regulator
F8267_RS21510	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F8267_RS21515	COG1140	nitrate reductase beta subunit
F8267_RS21520	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F8267_RS21525	COG2181	nitrate reductase activity
F8267_RS21530	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F8267_RS21535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F8267_RS21555	COG0625	glutathione transferase activity
F8267_RS21560	COG3619	membrane
F8267_RS21570	COG1126	abc transporter atp-binding protein
F8267_RS21590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS21595	COG1473	amidohydrolase
F8267_RS21600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F8267_RS21630	COG4772	TonB-dependent receptor
F8267_RS21635	COG3691	Protein conserved in bacteria
F8267_RS21640	COG2130	NADP-dependent
F8267_RS21650	COG1247	-acetyltransferase
F8267_RS21655	COG3238	Protein conserved in bacteria
F8267_RS21665	COG0747	negative chemotaxis
F8267_RS21670	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS21675	COG2267	carboxylic ester hydrolase activity
F8267_RS21695	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS21700	COG1177	transmembrane transport
F8267_RS21705	COG1176	ABC-type spermidine putrescine transport system, permease component I
F8267_RS21710	COG3842	ATPase activity
F8267_RS21715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F8267_RS21720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F8267_RS21725	COG1271	oxidase subunit
F8267_RS21730	COG1294	oxidase, subunit
F8267_RS21750	COG1396	sequence-specific DNA binding
F8267_RS21755	COG3135	benzoate transporter
F8267_RS21760	COG2207	Transcriptional regulator
F8267_RS21760	COG3708	Transcriptional regulator
F8267_RS21765	COG0697	spore germination
F8267_RS21775	COG0747	negative chemotaxis
F8267_RS21780	COG2195	Cleaves the N-terminal amino acid of tripeptides
F8267_RS21785	COG0500	methyltransferase
F8267_RS21790	COG1275	C4-dicarboxylate transporter malic acid transport protein
F8267_RS21795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F8267_RS21800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F8267_RS21825	COG0436	Aminotransferase
F8267_RS21835	COG1335	isochorismatase
F8267_RS21840	COG0583	DNA-binding transcription factor activity
F8267_RS21845	COG2272	Belongs to the type-B carboxylesterase lipase family
F8267_RS21850	COG5383	Protein conserved in bacteria
F8267_RS21855	COG3485	protocatechuate 3,4-dioxygenase
F8267_RS21860	COG3485	protocatechuate 3,4-dioxygenase
F8267_RS21865	COG0583	DNA-binding transcription factor activity
F8267_RS21905	COG3038	cytochrome b561
F8267_RS21915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F8267_RS21920	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F8267_RS21925	COG1113	amino acid transport
F8267_RS21930	COG2988	succinylglutamate desuccinylase activity
F8267_RS21935	COG3724	N-succinylarginine dihydrolase activity
F8267_RS21940	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS21945	COG3138	arginine N-succinyltransferase
F8267_RS21950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F8267_RS21955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F8267_RS21980	COG4122	O-methyltransferase activity
F8267_RS21985	COG1643	Atp-dependent helicase
F8267_RS22000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F8267_RS22005	COG3327	negative regulation of DNA-templated transcription, initiation
F8267_RS22010	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F8267_RS22015	COG0183	Belongs to the thiolase family
F8267_RS22020	COG2050	protein possibly involved in aromatic compounds catabolism
F8267_RS22025	COG1250	3-hydroxyacyl-CoA dehydrogenase
F8267_RS22030	COG1024	Enoyl-CoA hydratase
F8267_RS22035	COG1024	Enoyl-CoA hydratase
F8267_RS22040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F8267_RS22045	COG2151	metal-sulfur cluster biosynthetic enzyme
F8267_RS22050	COG3396	Phenylacetate-CoA oxygenase
F8267_RS22055	COG3460	Phenylacetate-CoA oxygenase
F8267_RS22060	COG3396	Phenylacetate-CoA oxygenase
F8267_RS22065	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS22065	COG2030	dehydratase
F8267_RS22080	COG1012	belongs to the aldehyde dehydrogenase family
F8267_RS22085	COG2207	Transcriptional regulator
F8267_RS22090	COG3784	Protein of unknown function (DUF1318)
F8267_RS22100	COG2911	Protein conserved in bacteria
F8267_RS22105	COG0586	Pfam SNARE associated Golgi protein
F8267_RS22110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F8267_RS22115	COG3187	Heat shock protein
F8267_RS22120	COG3042	response to heat
F8267_RS22130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F8267_RS22135	COG0589	response to stress
F8267_RS22140	COG3549	Plasmid maintenance system killer
F8267_RS22145	COG3093	addiction module antidote protein HigA
F8267_RS22160	COG0513	Belongs to the DEAD box helicase family
F8267_RS22170	COG0456	acetyltransferase
F8267_RS22175	COG1940	carbohydrate kinase activity
F8267_RS22195	COG1940	carbohydrate kinase activity
F8267_RS22205	COG4172	Belongs to the ABC transporter superfamily
F8267_RS22210	COG1349	DNA-binding transcription factor activity
F8267_RS22215	COG0673	inositol 2-dehydrogenase activity
F8267_RS22225	COG0693	protein deglycase activity
F8267_RS22265	COG4580	involved in the transport of maltose and maltodextrins
F8267_RS22270	COG2211	Major facilitator Superfamily
F8267_RS22275	COG3507	Belongs to the glycosyl hydrolase 43 family
F8267_RS22280	COG0656	L-ascorbic acid biosynthetic process
F8267_RS22290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F8267_RS22300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F8267_RS22315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS22325	COG4166	transmembrane transport
F8267_RS22330	COG2866	Carboxypeptidase
F8267_RS22335	COG4948	Mandelate Racemase Muconate Lactonizing
F8267_RS22340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F8267_RS22345	COG3180	Ammonia monooxygenase
F8267_RS22360	COG3106	COG3106 Predicted ATPase
F8267_RS22370	COG1983	PspC domain protein
F8267_RS22380	COG1842	Phage shock protein A
F8267_RS22385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F8267_RS22395	COG1473	amidohydrolase
F8267_RS22430	COG1278	Cold shock
F8267_RS22440	COG3459	Glycosyltransferase 36 associated
F8267_RS22455	COG1560	Kdo2-lipid A biosynthetic process
F8267_RS22490	COG1196	nuclear chromosome segregation
F8267_RS22490	COG1196	nuclear chromosome segregation
F8267_RS22745	COG4712	double-strand break repair protein
F8267_RS22750	COG0629	single-stranded DNA binding
F8267_RS22800	COG4171	peptide transport system, permease
F8267_RS22810	COG4172	Belongs to the ABC transporter superfamily
F8267_RS22815	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F8267_RS22825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F8267_RS22830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F8267_RS22830	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F8267_RS22845	COG1349	DNA-binding transcription factor activity
F8267_RS22855	COG0023	Translation Initiation Factor
F8267_RS22865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F8267_RS22870	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F8267_RS22875	COG0671	phosphoesterase, PA-phosphatase related
F8267_RS22885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F8267_RS22910	COG0616	signal peptide processing
F8267_RS22915	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS22920	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F8267_RS22925	COG2207	Transcriptional regulator
F8267_RS22930	COG1472	Belongs to the glycosyl hydrolase 3 family
F8267_RS22935	COG2211	Major facilitator Superfamily
F8267_RS22945	COG1716	ATPase activity
F8267_RS22945	COG5001	Diguanylate cyclase
F8267_RS22950	COG1716	ATPase activity
F8267_RS22950	COG5001	Diguanylate cyclase
F8267_RS22955	COG0009	L-threonylcarbamoyladenylate synthase
F8267_RS22965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F8267_RS22970	COG0512	Glutamine amidotransferase of anthranilate synthase
F8267_RS22970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F8267_RS22975	COG0135	phosphoribosylanthranilate isomerase activity
F8267_RS22975	COG0134	indole-3-glycerol-phosphate synthase activity
F8267_RS22995	COG1063	alcohol dehydrogenase
F8267_RS23000	COG1566	PFAM secretion protein HlyD family protein
F8267_RS23015	COG0583	DNA-binding transcription factor activity
F8267_RS23020	COG3047	cAMP biosynthetic process
F8267_RS23025	COG0727	PFAM Uncharacterised protein family (UPF0153)
F8267_RS23050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F8267_RS23055	COG1988	membrane-bound metal-dependent
F8267_RS23070	COG0753	catalase activity
F8267_RS23080	COG1486	melibiose metabolic process
F8267_RS23085	COG1917	Cupin 2, conserved barrel domain protein
F8267_RS23085	COG2169	Transcriptional regulator
F8267_RS23090	COG1447	Phosphotransferase system cellobiose-specific component IIA
F8267_RS23095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F8267_RS23100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F8267_RS23105	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F8267_RS23115	COG0322	excinuclease ABC activity
F8267_RS23120	COG3678	ATP-independent chaperone mediated protein folding
F8267_RS23135	COG3138	arginine N-succinyltransferase
F8267_RS23145	COG0708	Exodeoxyribonuclease III
F8267_RS23150	COG0398	Pfam SNARE associated Golgi protein
F8267_RS23155	COG0398	Pfam SNARE associated Golgi protein
F8267_RS23160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F8267_RS23165	COG4134	Bacterial extracellular solute-binding protein
F8267_RS23170	COG4135	transport system, permease component
F8267_RS23175	COG4136	ATPase activity
F8267_RS23180	COG2897	thiosulfate sulfurtransferase activity
F8267_RS23185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F8267_RS23190	COG0494	nUDIX hydrolase
F8267_RS23200	COG3321	synthase
F8267_RS23200	COG0604	alcohol dehydrogenase
F8267_RS23200	COG1028	Short-chain dehydrogenase reductase Sdr
F8267_RS23215	COG0709	Synthesizes selenophosphate from selenide and ATP
F8267_RS23225	COG0778	Nitroreductase
F8267_RS23230	COG0616	signal peptide processing
F8267_RS23235	COG0252	asparaginase activity
F8267_RS23240	COG1335	isochorismatase
F8267_RS23250	COG3139	Protein of unknown function (DUF1315)
F8267_RS23270	COG3713	MltA-interacting MipA family protein
F8267_RS23275	COG2766	serine protein kinase
F8267_RS23290	COG2199	diguanylate cyclase activity
F8267_RS23295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F8267_RS23305	COG2207	Transcriptional regulator
F8267_RS23310	COG2807	transmembrane transport
F8267_RS23315	COG0504	CTP synthase activity
F8267_RS23320	COG3189	MarR family transcriptional regulator
F8267_RS23325	COG3042	response to heat
F8267_RS23330	COG2203	Gaf domain
F8267_RS23330	COG2199	diguanylate cyclase activity
F8267_RS23350	COG3182	Iron-regulated membrane protein
F8267_RS23360	COG1560	Kdo2-lipid A biosynthetic process
F8267_RS23365	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F8267_RS23370	COG3706	GGDEF domain
F8267_RS23400	COG3209	COG3209 Rhs family protein
F8267_RS23440	COG3209	COG3209 Rhs family protein
F8267_RS23450	COG3209	COG3209 Rhs family protein
F8267_RS23460	COG3501	Rhs element vgr protein
F8267_RS23470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F8267_RS23555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F8267_RS23565	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F8267_RS23585	COG1760	l-serine dehydratase
F8267_RS23590	COG1882	Formate acetyltransferase
F8267_RS23595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F8267_RS23610	COG0583	DNA-binding transcription factor activity
F8267_RS23615	COG2814	Major facilitator Superfamily
F8267_RS23630	COG4774	siderophore transport
F8267_RS23640	COG1619	proteins homologs of microcin C7 resistance protein MccF
F8267_RS23660	COG2719	SpoVR family
F8267_RS23690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F8267_RS23690	COG2755	lipolytic protein G-D-S-L family
F8267_RS23700	COG0179	Fumarylacetoacetate (FAA) hydrolase
F8267_RS23715	COG2894	cell division
F8267_RS23725	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F8267_RS23735	COG3065	identical protein binding
F8267_RS23745	COG1199	ATP-dependent helicase activity
F8267_RS23750	COG0251	oxidation-reduction process
F8267_RS23770	COG1760	l-serine dehydratase
F8267_RS23775	COG2200	EAL domain
F8267_RS23780	COG1253	flavin adenine dinucleotide binding
F8267_RS23785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F8267_RS23785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F8267_RS23790	COG3715	PTS system
F8267_RS23795	COG3716	PTS system mannose fructose sorbose family IID component
F8267_RS23810	COG2226	methyltransferase
F8267_RS23815	COG0768	penicillin binding
F8267_RS23845	COG1414	Transcriptional regulator
F8267_RS23850	COG2814	Major facilitator Superfamily
F8267_RS23875	COG2995	paraquat-inducible protein a
F8267_RS23880	COG3008	intermembrane lipid transfer
F8267_RS23905	COG2990	Protein conserved in bacteria